{ "directed": true, "multigraph": false, "graph": {}, "nodes": [ { "id": "reaction_10087663", "map_id": "none", "name": "Y693-STAT4 dimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087657", "map_id": "none", "name": "p-Y693-STAT4 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N0R2", "map_id": "F1N0R2", "name": "phospho-STAT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030584", "map_id": "ENSBTAT00000030584", "name": "phospho-STAT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087661", "map_id": "none", "name": "Y963-STAT4 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087795", "map_id": "none", "name": "p-Y693-STAT4 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087655", "map_id": "F1N0R2", "name": "phospho-STAT4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10087650", "map_id": "none", "name": "IL12B translocates from the cytosol to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087648", "map_id": "A0A3Q1LXM0", "name": "IL12B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000077926", "map_id": "ENSBTAT00000077926", "name": "IL12B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049902", "map_id": "A0A3Q1LXM0", "name": "IL12B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10087732", "map_id": "none", "name": "IL12B:IL12B translocates from ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10087728", "map_id": "none", "name": "2xIL12B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A3Q1LXM0", "map_id": "A0A3Q1LXM0", "name": "IL12B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087730", "map_id": "none", "name": "2xIL12B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10088519", "map_id": "none", "name": "p-Y693-STAT4 dissociates after IL12:IL12R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10088517", "map_id": "none", "name": "2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MX29", "map_id": "G3MX29", "name": "IL12RB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064950", "map_id": "ENSBTAT00000064950", "name": "IL12RB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCX4", "map_id": "F1MCX4", "name": "phospho-TYK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015532", "map_id": "ENSBTAT00000015532", "name": "phospho-TYK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0D6", "map_id": "F1N0D6", "name": "phospho-JAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004101", "map_id": "ENSBTAT00000004101", "name": "phospho-JAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCP6", "map_id": "E1BCP6", "name": "phospho-JAK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015986", "map_id": "ENSBTAT00000015986", "name": "phospho-JAK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045423", "map_id": "none", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_374935", "map_id": "CHEBI:18357", "name": "NAd", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_209789", "map_id": "CHEBI:18357", "name": "NAd", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045416", "map_id": "none", "name": "SLC22A1,SLC22A2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BHW6", "map_id": "E1BHW6", "name": "SLC22A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012607", "map_id": "ENSBTAT00000012607", "name": "SLC22A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046151", "map_id": "none", "name": "MAOA:FAD deaminates DA to DOPAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29356", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29368", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_159362", "map_id": "CHEBI:18243", "name": "DA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9677997", "map_id": "CHEBI:41941", "name": "DOPAC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29382", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29408", "map_id": "CHEBI:16240", "name": "H2O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037997", "map_id": "none", "name": "MAOA:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P21398", "map_id": "P21398", "name": "MAOA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021570", "map_id": "ENSBTAT00000021570", "name": "MAOA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113596", "map_id": "CHEBI:16238", "name": "FAD", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10046153", "map_id": "none", "name": "MAOA:FAD deaminates 3MT to HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8954997", "map_id": "CHEBI:1582", "name": "3MT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9677992", "map_id": "CHEBI:545959", "name": "HVA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10088657", "map_id": "none", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71284", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71285", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088654", "map_id": "F1MCR3", "name": "TOMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000003905", "map_id": "ENSBTAT00000003905", "name": "TOMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046552", "map_id": "none", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113526", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_380598", "map_id": "CHEBI:50157", "name": "HIALD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113529", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_380593", "map_id": "CHEBI:27823", "name": "HIAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29362", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10034212", "map_id": "none", "name": "ALDH2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P20000", "map_id": "P20000", "name": "ALDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011521", "map_id": "ENSBTAT00000011521", "name": "ALDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038000", "map_id": "none", "name": "MAOA:FAD oxidatively deaminates of 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209914", "map_id": "CHEBI:28790", "name": "5HT", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_500604", "map_id": "CHEBI:50157", "name": "5HIALD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10078658", "map_id": "none", "name": "BTG2 binds CCR4-NOT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10078654", "map_id": "none", "name": "CCR4-NOT Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N4H7", "map_id": "A0A3Q1N4H7", "name": "TNKS1BP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087280", "map_id": "ENSBTAT00000087280", "name": "TNKS1BP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5L7", "map_id": "A0A3Q1M5L7", "name": "CNOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071934", "map_id": "ENSBTAT00000071934", "name": "CNOT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJH0", "map_id": "E1BJH0", "name": "CNOT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016027", "map_id": "ENSBTAT00000016027", "name": "CNOT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC01", "map_id": "Q3ZC01", "name": "CNOT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024009", "map_id": "ENSBTAT00000024009", "name": "CNOT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB47", "map_id": "A7MB47", "name": "CNOT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004955", "map_id": "ENSBTAT00000004955", "name": "CNOT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCS1", "map_id": "E1BCS1", "name": "CNOT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019836", "map_id": "ENSBTAT00000019836", "name": "CNOT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QR51", "map_id": "A6QR51", "name": "CNOT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023088", "map_id": "ENSBTAT00000023088", "name": "CNOT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ME75", "map_id": "A0A3Q1ME75", "name": "CNOT6L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075104", "map_id": "ENSBTAT00000075104", "name": "CNOT6L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHL0", "map_id": "E1BHL0", "name": "CNOT11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010879", "map_id": "ENSBTAT00000010879", "name": "CNOT11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N546", "map_id": "A0A3Q1N546", "name": "CNOT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071100", "map_id": "ENSBTAT00000071100", "name": "CNOT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078604", "map_id": "F1MNK6", "name": "BTG2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020860", "map_id": "ENSBTAT00000020860", "name": "BTG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078656", "map_id": "none", "name": "BTG2:CCR4-NOT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MNK6", "map_id": "F1MNK6", "name": "BTG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081380", "map_id": "none", "name": "PLK2 phosphorylates NPM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113592", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10081359", "map_id": "none", "name": "Homologues of NPM1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LXL7", "map_id": "A0A3Q1LXL7", "name": "LOC511386", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054559", "map_id": "ENSBTAT00000054559", "name": "LOC511386", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCL3", "map_id": "E1BCL3", "name": "NPM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053056", "map_id": "ENSBTAT00000053056", "name": "NPM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTV9", "map_id": "F1MTV9", "name": "NPM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LR94", "map_id": "A0A3Q1LR94", "name": "NPM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29370", "map_id": "CHEBI:456216", "name": "ADP", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10081373", "map_id": "none", "name": "Homologues of p-S4-NPM1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081377", "map_id": "E1BP17", "name": "PLK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022307", "map_id": "ENSBTAT00000022307", "name": "PLK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081499", "map_id": "none", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037648", "map_id": "Q0VC36", "name": "SFN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000012154", "map_id": "ENSBTAT00000012154", "name": "SFN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037650", "map_id": "none", "name": "SFN dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC36", "map_id": "Q0VC36", "name": "SFN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078349", "map_id": "none", "name": "GADD45A binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077951", "map_id": "Q3ZBN6", "name": "GADD45A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000033450", "map_id": "ENSBTAT00000033450", "name": "GADD45A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078345", "map_id": "Q2TA06", "name": "AURKA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000044590", "map_id": "ENSBTAT00000044590", "name": "AURKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078347", "map_id": "none", "name": "GADD45A:AURKA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2TA06", "map_id": "Q2TA06", "name": "AURKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBN6", "map_id": "Q3ZBN6", "name": "GADD45A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077955", "map_id": "none", "name": "GADD45A binds PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10039892", "map_id": "none", "name": "PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3ZBW4", "map_id": "Q3ZBW4", "name": "PCNA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007967", "map_id": "ENSBTAT00000007967", "name": "PCNA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077953", "map_id": "none", "name": "GADD45A:PCNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10088542", "map_id": "none", "name": "E2F7 binds E2F8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088530", "map_id": "A0A452DIR4", "name": "E2F7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000022518", "map_id": "ENSBTAT00000022518", "name": "E2F7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088538", "map_id": "A0A3Q1M173", "name": "E2F8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000086675", "map_id": "ENSBTAT00000086675", "name": "E2F8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088540", "map_id": "none", "name": "E2F7:E2F8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M173", "map_id": "A0A3Q1M173", "name": "E2F8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIR4", "map_id": "A0A452DIR4", "name": "E2F7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088546", "map_id": "none", "name": "E2F8 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088544", "map_id": "none", "name": "E2F8 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10088534", "map_id": "none", "name": "E2F7 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088532", "map_id": "none", "name": "E2F7 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10041386", "map_id": "none", "name": "CYP21A2 21-hydroxylates PROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193055", "map_id": "CHEBI:17026", "name": "P4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_70106", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29364", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_194037", "map_id": "CHEBI:16973", "name": "11DCORST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29366", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041383", "map_id": "G3X6I9", "name": "CYP21A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000007353", "map_id": "ENSBTAT00000007353", "name": "CYP21A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041393", "map_id": "none", "name": "CYP11B2 oxidises 18HCORST to ALDO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_194012", "map_id": "CHEBI:16485", "name": "18HCORST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113533", "map_id": "CHEBI:15379", "name": "O2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_113600", "map_id": "CHEBI:16474", "name": "NADPH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193982", "map_id": "CHEBI:27584", "name": "ALDO", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_113563", "map_id": "CHEBI:18009", "name": "NADP+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113521", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10041390", "map_id": "F1MWH3", "name": "CYP11B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000055451", "map_id": "ENSBTAT00000055451", "name": "CYP11B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041269", "map_id": "none", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196344", "map_id": "CHEBI:63837", "name": "pregn-5-ene-3,20-dione", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041253", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P14893", "map_id": "P14893", "name": "HSD3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087114", "map_id": "ENSBTAT00000087114", "name": "HSD3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041267", "map_id": "none", "name": "glyco-Lutropin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P01217", "map_id": "P01217", "name": "CGA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078886", "map_id": "ENSBTAT00000078886", "name": "CGA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04651", "map_id": "P04651", "name": "LHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057054", "map_id": "ENSBTAT00000057054", "name": "LHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041397", "map_id": "none", "name": "CYP11B2 18-hydroxylates CORST to 18HCORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_194005", "map_id": "CHEBI:16827", "name": "CORST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041719", "map_id": "none", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193103", "map_id": "CHEBI:16581", "name": "PREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29360", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73473", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041415", "map_id": "none", "name": "CYP11B2 oxidises 11DCORST to CORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193988", "map_id": "CHEBI:16973", "name": "11DCORST", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10076281", "map_id": "none", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193132", "map_id": "CHEBI:16469", "name": "EST17b", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193066", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076278", "map_id": "Q2KIS5", "name": "HSD17B11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008272", "map_id": "ENSBTAT00000008272", "name": "HSD17B11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077113", "map_id": "none", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696835", "map_id": "CHEBI:16469", "name": "EST17b", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5696848", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10077110", "map_id": "F1N678", "name": "AKR1B10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000002073", "map_id": "ENSBTAT00000002073", "name": "AKR1B10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041277", "map_id": "none", "name": "CYP19A1 hydroxylates ANDST to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193079", "map_id": "CHEBI:16422", "name": "ANDST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29460", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041274", "map_id": "F2Z4F2", "name": "CYP19A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000019823", "map_id": "ENSBTAT00000019823", "name": "CYP19A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051676", "map_id": "none", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051673", "map_id": "none", "name": "HSD17B1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1JQD0", "map_id": "Q1JQD0", "name": "HSD17B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064720", "map_id": "ENSBTAT00000064720", "name": "HSD17B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041299", "map_id": "none", "name": "CYP19A1 hydroxylates TEST to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193057", "map_id": "CHEBI:17347", "name": "TEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10084679", "map_id": "none", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176619", "map_id": "CHEBI:16469", "name": "E2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084676", "map_id": "Q0PHW6", "name": "HSD17B2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000004193", "map_id": "ENSBTAT00000004193", "name": "HSD17B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041692", "map_id": "none", "name": "Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10041690", "map_id": "none", "name": "STAR:CHOL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q28918", "map_id": "Q28918", "name": "STAR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047426", "map_id": "ENSBTAT00000047426", "name": "STAR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193840", "map_id": "CHEBI:16113", "name": "CHOL", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_193156", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10041688", "map_id": "Q28918", "name": "STAR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10041716", "map_id": "none", "name": "CHOL translocates from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10041714", "map_id": "none", "name": "STARD3:STARD3NL, STARD4,6:CHOL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BKK4", "map_id": "E1BKK4", "name": "STARD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015578", "map_id": "ENSBTAT00000015578", "name": "STARD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCL2", "map_id": "Q0VCL2", "name": "STARD3NL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057451", "map_id": "ENSBTAT00000057451", "name": "STARD3NL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041712", "map_id": "none", "name": "STARD3:STARD3NL, STARD4,6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041684", "map_id": "none", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196095", "map_id": "CHEBI:17998", "name": "ISCAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196066", "map_id": "CHEBI:63910", "name": "MePeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041681", "map_id": "none", "name": "Homologues of AKR1B1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M9Q1", "map_id": "A0A3Q1M9Q1", "name": "AKR1B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078546", "map_id": "ENSBTAT00000078546", "name": "AKR1B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBL5", "map_id": "A0A3Q1MBL5", "name": "AKR1B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041290", "map_id": "none", "name": "CYP17A1 cleaves 17aHPREG to DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193124", "map_id": "CHEBI:28750", "name": "17aHPREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29510", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176626", "map_id": "CHEBI:28689", "name": "DHEA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041281", "map_id": "F1MJA7", "name": "CYP17A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000074189", "map_id": "ENSBTAT00000074189", "name": "CYP17A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041288", "map_id": "P01190", "name": "POMC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010386", "map_id": "ENSBTAT00000010386", "name": "POMC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050650", "map_id": "none", "name": "SRD5A1 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_469662", "map_id": "CHEBI:16330", "name": "DHTEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050647", "map_id": "A5PJS2", "name": "SRD5A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000020570", "map_id": "ENSBTAT00000020570", "name": "SRD5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041293", "map_id": "none", "name": "CYP17A1 17-hydroxylates P4 to 17aHPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193092", "map_id": "CHEBI:17252", "name": "17aHPROG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041295", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10092062", "map_id": "none", "name": "SRD5A2 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092059", "map_id": "E1BJY8", "name": "SRD5A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000004043", "map_id": "ENSBTAT00000004043", "name": "SRD5A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041297", "map_id": "none", "name": "CYP17A1 cleaves 17aHPROG to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10092065", "map_id": "none", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069495", "map_id": "E1BCQ0", "name": "SRD5A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000019855", "map_id": "ENSBTAT00000019855", "name": "SRD5A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041284", "map_id": "none", "name": "CYP17A1 17-hydroxylates PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041721", "map_id": "none", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196366", "map_id": "CHEBI:63843", "name": "pregn-5-ene-3,20-dione-17-ol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10057880", "map_id": "none", "name": "Corticosteroids bind to CBG in blood", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_1449707", "map_id": "none", "name": "Corticosteroids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_194011", "map_id": "CHEBI:17650", "name": "CORT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10057876", "map_id": "E1BF81", "name": "SERPINA6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000023402", "map_id": "ENSBTAT00000023402", "name": "SERPINA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057878", "map_id": "none", "name": "CBG:Corticosteroids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BF81", "map_id": "E1BF81", "name": "SERPINA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041424", "map_id": "none", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_193977", "map_id": "CHEBI:17650", "name": "CORT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_194035", "map_id": "CHEBI:16962", "name": "COR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041421", "map_id": "none", "name": "HSD11B1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F6PTG3", "map_id": "F6PTG3", "name": "HSD11B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020078", "map_id": "ENSBTAT00000020078", "name": "HSD11B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041379", "map_id": "none", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041395", "map_id": "none", "name": "CYP21A2 oxidises 17HPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193966", "map_id": "CHEBI:28324", "name": "11-deoxycortisol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041412", "map_id": "none", "name": "CYP11B1 oxidises 11DCORT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193998", "map_id": "CHEBI:28324", "name": "11DCORT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10041409", "map_id": "none", "name": "Cytochrome P450 (CYP11B1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "F1MG97", "map_id": "F1MG97", "name": "CYP11B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MU47", "map_id": "F1MU47", "name": "LOC112449566", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006034", "map_id": "ENSBTAT00000006034", "name": "LOC112449566", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWH3", "map_id": "F1MWH3", "name": "CYP11B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034240", "map_id": "none", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29398", "map_id": "CHEBI:15361", "name": "PYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29708", "map_id": "CHEBI:422", "name": "LACT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033668", "map_id": "none", "name": "LDH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P19858", "map_id": "P19858", "name": "LDHA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056276", "map_id": "ENSBTAT00000056276", "name": "LDHA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4R3", "map_id": "A0A3Q1M4R3", "name": "LDHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045699", "map_id": "ENSBTAT00000045699", "name": "LDHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNS9", "map_id": "E1BNS9", "name": "LDHC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003234", "map_id": "ENSBTAT00000003234", "name": "LDHC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089721", "map_id": "none", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10089717", "map_id": "F6Q200", "name": "PDK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000011523", "map_id": "ENSBTAT00000011523", "name": "PDK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9010792", "map_id": "none", "name": "DCA", "type": "inhibitor", "sub_type": "other", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10089719", "map_id": "none", "name": "DCA:PDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F6Q200", "map_id": "F6Q200", "name": "PDK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089728", "map_id": "none", "name": "GSTZ1 dimer dehalogenates DCA to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_904849", "map_id": "CHEBI:16891", "name": "glyoxylate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_3301973", "map_id": "CHEBI:17883", "name": "HCl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10089725", "map_id": "none", "name": "GSTZ1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MEZ2", "map_id": "A0A3Q1MEZ2", "name": "GSTZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075831", "map_id": "ENSBTAT00000075831", "name": "GSTZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29450", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1655887", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10076468", "map_id": "none", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694074", "map_id": "CHEBI:17158", "name": "MGXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5694130", "map_id": "CHEBI:15694", "name": "(R)-S-LGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076465", "map_id": "none", "name": "GLO1 dimer:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_29426", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "A4FUZ1", "map_id": "A4FUZ1", "name": "GLO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016884", "map_id": "ENSBTAT00000016884", "name": "GLO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033671", "map_id": "none", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10051980", "map_id": "none", "name": "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_880013", "map_id": "CHEBI:32797", "name": "2HG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113594", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_31649", "map_id": "CHEBI:17877", "name": "FADH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10051977", "map_id": "A7MBI3", "name": "L2HGDH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000020226", "map_id": "ENSBTAT00000020226", "name": "L2HGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051973", "map_id": "none", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_879997", "map_id": "CHEBI:32796", "name": "2HG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10051970", "map_id": "Q1JPD3", "name": "D2HGDH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000081426", "map_id": "ENSBTAT00000081426", "name": "D2HGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_880069", "map_id": "CHEBI:27638", "name": "Co2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_880067", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113527", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10033868", "map_id": "none", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113559", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113587", "map_id": "CHEBI:30744", "name": "OAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29374", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29654", "map_id": "CHEBI:30769", "name": "CIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033865", "map_id": "none", "name": "CS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q29RK1", "map_id": "Q29RK1", "name": "CS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005730", "map_id": "ENSBTAT00000005730", "name": "CS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050446", "map_id": "none", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29938", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29376", "map_id": "CHEBI:16526", "name": "CO2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10050443", "map_id": "none", "name": "IDH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q04467", "map_id": "Q04467", "name": "IDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018741", "map_id": "ENSBTAT00000018741", "name": "IDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089808", "map_id": "none", "name": "ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113544", "map_id": "CHEBI:30797", "name": "MAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113557", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10089805", "map_id": "none", "name": "ME3:Mg2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_29926", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q0VCX7", "map_id": "Q0VCX7", "name": "ME3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000306", "map_id": "ENSBTAT00000000306", "name": "ME3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089795", "map_id": "none", "name": "ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10089792", "map_id": "none", "name": "ME2:Mg2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MWG7", "map_id": "A0A3Q1MWG7", "name": "ME2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074198", "map_id": "ENSBTAT00000074198", "name": "ME2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113588", "map_id": "CHEBI:18012", "name": "FUMA", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113593", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10050437", "map_id": "none", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5462", "compartment_display": "mitochondrion" }, { "id": "species_10050434", "map_id": "none", "name": "NNT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P11024", "map_id": "P11024", "name": "NNT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080867", "map_id": "ENSBTAT00000080867", "name": "NNT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089782", "map_id": "none", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10089779", "map_id": "none", "name": "FAHD1:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q2HJ98", "map_id": "Q2HJ98", "name": "FAHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046873", "map_id": "ENSBTAT00000046873", "name": "FAHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073835", "map_id": "none", "name": "Rheb in the MTORC1 complex hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039125", "map_id": "none", "name": "Active mTORC1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "A0A3Q1LSR3", "map_id": "A0A3Q1LSR3", "name": "RHEB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073291", "map_id": "ENSBTAT00000073291", "name": "RHEB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29438", "map_id": "CHEBI:15996", "name": "GTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "F1MG06", "map_id": "F1MG06", "name": "RPTOR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003739", "map_id": "ENSBTAT00000003739", "name": "RPTOR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QU5", "map_id": "Q17QU5", "name": "MLST8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053181", "map_id": "ENSBTAT00000053181", "name": "MLST8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29420", "map_id": "CHEBI:17552", "name": "GDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "A0A3Q1MVT8", "map_id": "A0A3Q1MVT8", "name": "RRAGD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075507", "map_id": "ENSBTAT00000075507", "name": "RRAGD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VD29", "map_id": "Q0VD29", "name": "RRAGC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012331", "map_id": "ENSBTAT00000012331", "name": "RRAGC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX43", "map_id": "Q3SX43", "name": "RRAGA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031476", "map_id": "ENSBTAT00000031476", "name": "RRAGA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T132", "map_id": "Q3T132", "name": "LAMTOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048084", "map_id": "ENSBTAT00000048084", "name": "LAMTOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QQ1", "map_id": "Q17QQ1", "name": "LAMTOR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047833", "map_id": "ENSBTAT00000047833", "name": "LAMTOR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2M2U3", "map_id": "Q2M2U3", "name": "LAMTOR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019980", "map_id": "ENSBTAT00000019980", "name": "LAMTOR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ68", "map_id": "Q3SZ68", "name": "LAMTOR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019928", "map_id": "ENSBTAT00000019928", "name": "LAMTOR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYC8", "map_id": "A0A3Q1LYC8", "name": "SLC38A9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084666", "map_id": "ENSBTAT00000084666", "name": "SLC38A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046585", "map_id": "none", "name": "mTORC1:Ragulator:Rag:GNP:RHEB:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10074507", "map_id": "none", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10074495", "map_id": "none", "name": "LC3:PE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "A7MB94", "map_id": "A7MB94", "name": "MAP1LC3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083637", "map_id": "ENSBTAT00000083637", "name": "MAP1LC3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9GJW7", "map_id": "Q9GJW7", "name": "GABARAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019814", "map_id": "ENSBTAT00000019814", "name": "GABARAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O41515", "map_id": "O41515", "name": "MAP1LC3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015449", "map_id": "ENSBTAT00000015449", "name": "MAP1LC3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1602375", "map_id": "CHEBI:16038", "name": "PE", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10074505", "map_id": "none", "name": "LC3:PE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "species_10052773", "map_id": "none", "name": "ESCRT-III", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3T0U5", "map_id": "Q3T0U5", "name": "CHMP2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018429", "map_id": "ENSBTAT00000018429", "name": "CHMP2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX42", "map_id": "Q3SX42", "name": "CHMP2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010436", "map_id": "ENSBTAT00000010436", "name": "CHMP2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJ35", "map_id": "Q2HJ35", "name": "CHMP4C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006291", "map_id": "ENSBTAT00000006291", "name": "CHMP4C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDY3", "map_id": "A2VDY3", "name": "CHMP4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008352", "map_id": "ENSBTAT00000008352", "name": "CHMP4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E32", "map_id": "Q08E32", "name": "CHMP4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017812", "map_id": "ENSBTAT00000017812", "name": "CHMP4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58CS7", "map_id": "Q58CS7", "name": "CHMP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018071", "map_id": "ENSBTAT00000018071", "name": "CHMP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148L0", "map_id": "Q148L0", "name": "CHMP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018623", "map_id": "ENSBTAT00000018623", "name": "CHMP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H704", "map_id": "A6H704", "name": "CHMP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017987", "map_id": "ENSBTAT00000017987", "name": "CHMP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074365", "map_id": "none", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5676030", "map_id": "CHEBI:26034", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_426639", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10074362", "map_id": "none", "name": "MTMR3,MTMR14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LMW0", "map_id": "A0A3Q1LMW0", "name": "MTMR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074360", "map_id": "ENSBTAT00000074360", "name": "MTMR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZ59", "map_id": "A0A3Q1LZ59", "name": "MTMR14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084980", "map_id": "ENSBTAT00000084980", "name": "MTMR14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074381", "map_id": "none", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074371", "map_id": "F1MZE2", "name": "ATG12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023301", "map_id": "ENSBTAT00000023301", "name": "ATG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074377", "map_id": "none", "name": "ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LXA9", "map_id": "A0A3Q1LXA9", "name": "ATG7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077815", "map_id": "ENSBTAT00000077815", "name": "ATG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074379", "map_id": "none", "name": "ATG12:ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZE2", "map_id": "F1MZE2", "name": "ATG12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074415", "map_id": "none", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074399", "map_id": "none", "name": "LC3 family", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10074413", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10074142", "map_id": "none", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073828", "map_id": "none", "name": "MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "E1BH45", "map_id": "E1BH45", "name": "RB1CC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076195", "map_id": "ENSBTAT00000076195", "name": "RB1CC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJE0", "map_id": "Q2HJE0", "name": "ATG101", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000651", "map_id": "ENSBTAT00000000651", "name": "ATG101", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074140", "map_id": "none", "name": "MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10046570", "map_id": "none", "name": "p-AMPK heterotrimer:AMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_76577", "map_id": "CHEBI:16027", "name": "AMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "F1MQV7", "map_id": "F1MQV7", "name": "phospho-PRKAA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024965", "map_id": "ENSBTAT00000024965", "name": "phospho-PRKAA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBG5", "map_id": "F1MBG5", "name": "phospho-PRKAA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000017", "map_id": "ENSBTAT00000000017", "name": "phospho-PRKAA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5BIS9", "map_id": "Q5BIS9", "name": "PRKAB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007798", "map_id": "ENSBTAT00000007798", "name": "PRKAB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B986", "map_id": "E1B986", "name": "PRKAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080624", "map_id": "ENSBTAT00000080624", "name": "PRKAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSS5", "map_id": "A0A3Q1MSS5", "name": "PRKAG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086099", "map_id": "ENSBTAT00000086099", "name": "PRKAG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074302", "map_id": "none", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5693050", "map_id": "CHEBI:17283", "name": "PI3P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10074298", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MUP4", "map_id": "A0A3Q1MUP4", "name": "WIPI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066992", "map_id": "ENSBTAT00000066992", "name": "WIPI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJ60", "map_id": "Q2KJ60", "name": "WIPI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016002", "map_id": "ENSBTAT00000016002", "name": "WIPI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074300", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B):PI3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "reaction_10090398", "map_id": "none", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074653", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10074659", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074655", "map_id": "A4FUE9", "name": "ATG10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083652", "map_id": "ENSBTAT00000083652", "name": "ATG10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074657", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7:ATG10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A4FUE9", "map_id": "A4FUE9", "name": "ATG10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070265", "map_id": "none", "name": "Pink1 is cleaved on healthy mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10070226", "map_id": "A5PJP5", "name": "PINK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "ENSBTAT00000029455", "map_id": "ENSBTAT00000029455", "name": "PINK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070263", "map_id": "A5PJP5", "name": "PINK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10070218", "map_id": "none", "name": "p62 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070214", "map_id": "O41515", "name": "MAP1LC3B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10070210", "map_id": "none", "name": "K48polyUB Mitophagy Substrates:SQSTM1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "D7GLD0", "map_id": "D7GLD0", "name": "MFN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080672", "map_id": "ENSBTAT00000080672", "name": "MFN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVE4", "map_id": "A0A3Q1LVE4", "name": "SQSTM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075019", "map_id": "ENSBTAT00000075019", "name": "SQSTM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1LZE3", "map_id": "Q1LZE3", "name": "MTERF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001994", "map_id": "ENSBTAT00000001994", "name": "MTERF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPL1", "map_id": "F1MPL1", "name": "MFN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013860", "map_id": "ENSBTAT00000013860", "name": "MFN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070216", "map_id": "none", "name": "LC3:K48polyUB Mitophagy Substrates:SQSTM1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070259", "map_id": "none", "name": "Pink1 is recruited from the cytoplasm to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070224", "map_id": "A5PJP5", "name": "PINK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10070256", "map_id": "none", "name": "TOMM40 Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "A6QPI6", "map_id": "A6QPI6", "name": "TOMM22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013405", "map_id": "ENSBTAT00000013405", "name": "TOMM22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI08", "map_id": "Q2KI08", "name": "TOMM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070920", "map_id": "ENSBTAT00000070920", "name": "TOMM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1LZB5", "map_id": "Q1LZB5", "name": "TOMM40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032251", "map_id": "ENSBTAT00000032251", "name": "TOMM40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E34", "map_id": "Q08E34", "name": "TOMM70", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019001", "map_id": "ENSBTAT00000019001", "name": "TOMM70", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A8YXZ8", "map_id": "A8YXZ8", "name": "TOMM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046547", "map_id": "ENSBTAT00000046547", "name": "TOMM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7B1", "map_id": "A6H7B1", "name": "TOMM20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000733", "map_id": "ENSBTAT00000000733", "name": "TOMM20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JY4", "map_id": "Q56JY4", "name": "TOMM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011817", "map_id": "ENSBTAT00000011817", "name": "TOMM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070261", "map_id": "none", "name": "Uncleaved Pink1 accumulates in damaged mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10070222", "map_id": "A5PJP5", "name": "PINK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10088891", "map_id": "none", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087624", "map_id": "F1N5S9", "name": "phospho-FUNDC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000002144", "map_id": "ENSBTAT00000002144", "name": "phospho-FUNDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088889", "map_id": "none", "name": "p-S17-FUNDC1:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "F1N5S9", "map_id": "F1N5S9", "name": "phospho-FUNDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087615", "map_id": "none", "name": "p-S13-FUNDC1 is dephosphorylated by PGAM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087608", "map_id": "F1N5S9", "name": "phospho-FUNDC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10087605", "map_id": "F1N5S9", "name": "FUNDC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10087612", "map_id": "E1BIE7", "name": "PGAM5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000009887", "map_id": "ENSBTAT00000009887", "name": "PGAM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087621", "map_id": "none", "name": "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087618", "map_id": "F1N5S9", "name": "phospho-FUNDC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10040957", "map_id": "E1BIM8", "name": "SRC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000011767", "map_id": "ENSBTAT00000011767", "name": "SRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073831", "map_id": "none", "name": "Active MTORC1 phosphorylates ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10073822", "map_id": "none", "name": "MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10050514", "map_id": "none", "name": "kainate receptor binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_210382", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10050510", "map_id": "none", "name": "Kainate Receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A2VE57", "map_id": "A2VE57", "name": "GRIK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070796", "map_id": "ENSBTAT00000070796", "name": "GRIK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_352022", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "Q2HJD2", "map_id": "Q2HJD2", "name": "GRIK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015567", "map_id": "ENSBTAT00000015567", "name": "GRIK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M9Y0", "map_id": "A0A3Q1M9Y0", "name": "GRIK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073656", "map_id": "ENSBTAT00000073656", "name": "GRIK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MM66", "map_id": "F1MM66", "name": "DLG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003326", "map_id": "ENSBTAT00000003326", "name": "DLG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MR28", "map_id": "A0A3Q1MR28", "name": "CALM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044622", "map_id": "ENSBTAT00000044622", "name": "CALM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBH0", "map_id": "A0A3Q1MBH0", "name": "DLG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084144", "map_id": "ENSBTAT00000084144", "name": "DLG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61602", "map_id": "P61602", "name": "NCALD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068404", "map_id": "ENSBTAT00000068404", "name": "NCALD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFJ1", "map_id": "A0A3Q1MFJ1", "name": "DLG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077778", "map_id": "ENSBTAT00000077778", "name": "DLG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCW8", "map_id": "F1MCW8", "name": "GRIK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022788", "map_id": "ENSBTAT00000022788", "name": "GRIK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050512", "map_id": "none", "name": "Kainate receptor-glutamate complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050517", "map_id": "none", "name": "Activation of Ca-permeable Kainate receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_74112", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_74016", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10045419", "map_id": "none", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10045421", "map_id": "none", "name": "Metabolism of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5279533", "map_id": "CHEBI:27852", "name": "3,4-dihydroxyphenylglycolaldehyde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_459", "compartment_display": "cytoplasm", "complex": "false" }, { "id": "reaction_10039481", "map_id": "none", "name": "TRAF6 binds MEKK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039473", "map_id": "Q3ZCC3", "name": "TRAF6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000021630", "map_id": "ENSBTAT00000021630", "name": "TRAF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039469", "map_id": "E1B847", "name": "MAP3K1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000018325", "map_id": "ENSBTAT00000018325", "name": "MAP3K1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039475", "map_id": "none", "name": "MEKK1:activated TRAF6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B847", "map_id": "E1B847", "name": "MAP3K1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZCC3", "map_id": "Q3ZCC3", "name": "TRAF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039479", "map_id": "Q3SX05", "name": "ECSIT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020029", "map_id": "ENSBTAT00000020029", "name": "ECSIT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050256", "map_id": "none", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039518", "map_id": "none", "name": "p-MAPK8,9,10", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LWJ8", "map_id": "A0A3Q1LWJ8", "name": "phospho-MAPK8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087439", "map_id": "ENSBTAT00000087439", "name": "phospho-MAPK8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJU7", "map_id": "A0A3Q1LJU7", "name": "phospho-MAPK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082454", "map_id": "ENSBTAT00000082454", "name": "phospho-MAPK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039505", "map_id": "none", "name": "p-MAPK8,9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10042826", "map_id": "none", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113518", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10041947", "map_id": "none", "name": "p-T1218, Y220 MAPK7 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A5PKJ4", "map_id": "A5PKJ4", "name": "MAPK7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001347", "map_id": "ENSBTAT00000001347", "name": "MAPK7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113550", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10042805", "map_id": "none", "name": "MAPK7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10042823", "map_id": "none", "name": "PP2A-ABdeltaC complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N1S8", "map_id": "F1N1S8", "name": "PPP2R5D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007277", "map_id": "ENSBTAT00000007277", "name": "PPP2R5D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043488", "map_id": "none", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10043479", "map_id": "none", "name": "ERK-specific DUSP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2T9T7", "map_id": "Q2T9T7", "name": "DUSP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078874", "map_id": "ENSBTAT00000078874", "name": "DUSP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MM08", "map_id": "F1MM08", "name": "DUSP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061049", "map_id": "ENSBTAT00000061049", "name": "DUSP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLS1", "map_id": "A6QLS1", "name": "DUSP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029212", "map_id": "ENSBTAT00000029212", "name": "DUSP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJ36", "map_id": "Q2KJ36", "name": "DUSP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006022", "map_id": "ENSBTAT00000006022", "name": "DUSP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043486", "map_id": "none", "name": "VRK3:DUSP3", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2YDN8", "map_id": "Q2YDN8", "name": "VRK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007054", "map_id": "ENSBTAT00000007054", "name": "VRK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041950", "map_id": "none", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_29358", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10041927", "map_id": "none", "name": "Ribosomal protein S6 kinase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MLN6", "map_id": "A0A3Q1MLN6", "name": "RPS6KA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073341", "map_id": "ENSBTAT00000073341", "name": "RPS6KA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNQ6", "map_id": "A0A3Q1LNQ6", "name": "RPS6KA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080174", "map_id": "ENSBTAT00000080174", "name": "RPS6KA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113582", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10041945", "map_id": "none", "name": "Phospho-Ribosomal protein S6 kinase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10050208", "map_id": "none", "name": "Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10039493", "map_id": "Q08DH1", "name": "phospho-JUN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000005279", "map_id": "ENSBTAT00000005279", "name": "phospho-JUN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050204", "map_id": "O77628", "name": "phospho-FOS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000005660", "map_id": "ENSBTAT00000005660", "name": "phospho-FOS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050206", "map_id": "none", "name": "p-2S-cJUN:p-2S,2T-cFOS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O77628", "map_id": "O77628", "name": "phospho-FOS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DH1", "map_id": "Q08DH1", "name": "phospho-JUN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039508", "map_id": "none", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10039489", "map_id": "Q08DH1", "name": "JUN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10050218", "map_id": "none", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050214", "map_id": "A0A3Q1MNG1", "name": "phospho-MAP2K3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081307", "map_id": "ENSBTAT00000081307", "name": "MAP2K3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050216", "map_id": "A0A3Q1MNG1", "name": "phospho-MAP2K3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10050254", "map_id": "none", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050233", "map_id": "A0A3Q1MNG1", "name": "MAP2K3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050251", "map_id": "none", "name": "K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B7Z0", "map_id": "E1B7Z0", "name": "TAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077920", "map_id": "ENSBTAT00000077920", "name": "TAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7T8", "map_id": "A0A3Q1M7T8", "name": "TAB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082809", "map_id": "ENSBTAT00000082809", "name": "TAB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LT51", "map_id": "A0A3Q1LT51", "name": "TAB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068866", "map_id": "ENSBTAT00000068866", "name": "TAB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CG53", "map_id": "P0CG53", "name": "UBB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022919", "map_id": "ENSBTAT00000022919", "name": "UBB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LU30", "map_id": "A0A3Q1LU30", "name": "RPS27A(1-76)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087088", "map_id": "ENSBTAT00000087088", "name": "RPS27A(1-76)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P63048", "map_id": "P63048", "name": "UBA52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010176", "map_id": "ENSBTAT00000010176", "name": "UBA52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050192", "map_id": "none", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050185", "map_id": "none", "name": "p-p38 MAPK: MAPKAPK2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M614", "map_id": "A0A3Q1M614", "name": "phospho-MAPKAPK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084476", "map_id": "ENSBTAT00000084476", "name": "phospho-MAPKAPK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X793", "map_id": "G3X793", "name": "phospho-MAPK11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022358", "map_id": "ENSBTAT00000022358", "name": "phospho-MAPK11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTT9", "map_id": "A0A3Q1LTT9", "name": "phospho-MAPK14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073013", "map_id": "ENSBTAT00000073013", "name": "phospho-MAPK14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050189", "map_id": "none", "name": "p-p38 MAPK:p-MAPKAPK2/3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10050196", "map_id": "none", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050194", "map_id": "none", "name": "p-p38 MAPK: p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050231", "map_id": "none", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050228", "map_id": "none", "name": "p38 MAPK:MAPKAPK2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10069253", "map_id": "none", "name": "NGEF exchanges GTP for GDP on RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037313", "map_id": "none", "name": "RHOA:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P61585", "map_id": "P61585", "name": "RHOA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005600", "map_id": "ENSBTAT00000005600", "name": "RHOA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037315", "map_id": "none", "name": "RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069250", "map_id": "none", "name": "EFNAs:p-EPHAs:SFKs:p-Y179-NGEF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7MB57", "map_id": "A7MB57", "name": "YES1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070883", "map_id": "ENSBTAT00000070883", "name": "YES1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIM8", "map_id": "E1BIM8", "name": "SRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0JNB0", "map_id": "A0JNB0", "name": "phospho-FYN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015730", "map_id": "ENSBTAT00000015730", "name": "phospho-FYN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N261", "map_id": "F1N261", "name": "LYN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075171", "map_id": "ENSBTAT00000075171", "name": "LYN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLY0", "map_id": "A6QLY0", "name": "EFNA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033972", "map_id": "ENSBTAT00000033972", "name": "EFNA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC64", "map_id": "Q3ZC64", "name": "EFNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004007", "map_id": "ENSBTAT00000004007", "name": "EFNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17R05", "map_id": "Q17R05", "name": "EFNA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080646", "map_id": "ENSBTAT00000080646", "name": "EFNA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7J8", "map_id": "A5D7J8", "name": "EFNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053096", "map_id": "ENSBTAT00000053096", "name": "EFNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N163", "map_id": "F1N163", "name": "EFNA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026958", "map_id": "ENSBTAT00000026958", "name": "EFNA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6H6", "map_id": "F1N6H6", "name": "EPHA10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033263", "map_id": "ENSBTAT00000033263", "name": "EPHA10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTB6", "map_id": "A0A3Q1MTB6", "name": "EPHA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067384", "map_id": "ENSBTAT00000067384", "name": "EPHA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJS9", "map_id": "E1BJS9", "name": "EPHA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008955", "map_id": "ENSBTAT00000008955", "name": "EPHA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKR1", "map_id": "F1MKR1", "name": "EPHA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037789", "map_id": "ENSBTAT00000037789", "name": "EPHA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BER5", "map_id": "E1BER5", "name": "EPHA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013238", "map_id": "ENSBTAT00000013238", "name": "EPHA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAA9", "map_id": "A0A3Q1MAA9", "name": "EPHA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083978", "map_id": "ENSBTAT00000083978", "name": "EPHA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJW2", "map_id": "A0A3Q1MJW2", "name": "EPHA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075696", "map_id": "ENSBTAT00000075696", "name": "EPHA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DA6", "map_id": "Q08DA6", "name": "NGEF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011773", "map_id": "ENSBTAT00000011773", "name": "NGEF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077455", "map_id": "none", "name": "JAKs bind LIFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10077414", "map_id": "E1BAT3", "name": "LIFR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000076709", "map_id": "ENSBTAT00000076709", "name": "LIFR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049952", "map_id": "none", "name": "JAK1, JAK2, (TYK2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10077416", "map_id": "none", "name": "JAKs:LIFR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BAT3", "map_id": "E1BAT3", "name": "LIFR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077422", "map_id": "none", "name": "OSM,LIF,CTF1 receptor complex binds gp130", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049956", "map_id": "E1BD36", "name": "IL6ST", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000023595", "map_id": "ENSBTAT00000023595", "name": "phospho-IL6ST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077418", "map_id": "none", "name": "OSM:OSMR,LIFR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N366", "map_id": "F1N366", "name": "OSM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021515", "map_id": "ENSBTAT00000021515", "name": "OSM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077420", "map_id": "none", "name": "LIF,OSM receptor complex:gp130", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BD36", "map_id": "E1BD36", "name": "phospho-IL6ST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077424", "map_id": "none", "name": "OSM binds LIFR:JAKs,OSMR:JAKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10077410", "map_id": "F1N366", "name": "OSM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10065517", "map_id": "none", "name": "PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_179856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_179838", "map_id": "CHEBI:16618", "name": "PI(3,4,5)P3", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10065514", "map_id": "none", "name": "DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MHG9", "map_id": "A0A3Q1MHG9", "name": "SYK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075168", "map_id": "ENSBTAT00000075168", "name": "SYK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MI53", "map_id": "F1MI53", "name": "KLRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074586", "map_id": "ENSBTAT00000074586", "name": "KLRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NAW3", "map_id": "A0A3Q1NAW3", "name": "TREM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070846", "map_id": "ENSBTAT00000070846", "name": "TREM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A2Z2AM52", "map_id": "A0A2Z2AM52", "name": "KLRC1-4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080723", "map_id": "ENSBTAT00000080723", "name": "KLRC1-4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A3R3B5", "map_id": "A3R3B5", "name": "NKG2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077363", "map_id": "ENSBTAT00000077363", "name": "NKG2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7L0", "map_id": "A0A3Q1M7L0", "name": "KLRC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075285", "map_id": "ENSBTAT00000075285", "name": "KLRC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A8E4Q0", "map_id": "A8E4Q0", "name": "KLRC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031648", "map_id": "ENSBTAT00000031648", "name": "KLRC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NM98", "map_id": "A0A3Q1NM98", "name": "LOC100140174", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071353", "map_id": "ENSBTAT00000071353", "name": "LOC100140174", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHY4", "map_id": "F1MHY4", "name": "LOC513869", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006472", "map_id": "ENSBTAT00000006472", "name": "LOC513869", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A3R3B4", "map_id": "A3R3B4", "name": "NKG2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPK9", "map_id": "F1MPK9", "name": "NKG2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055860", "map_id": "ENSBTAT00000055860", "name": "NKG2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A140T8B5", "map_id": "A0A140T8B5", "name": "KLRD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037859", "map_id": "ENSBTAT00000037859", "name": "KLRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N4Y9", "map_id": "A0A3Q1N4Y9", "name": "LOC618565", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068807", "map_id": "ENSBTAT00000068807", "name": "LOC618565", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MU93", "map_id": "A0A3Q1MU93", "name": "B2M(21-119)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086688", "map_id": "ENSBTAT00000086688", "name": "B2M(21-119)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01888", "map_id": "P01888", "name": "B2M", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016359", "map_id": "ENSBTAT00000016359", "name": "B2M", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32871", "map_id": "P32871", "name": "PIK3CA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072391", "map_id": "ENSBTAT00000072391", "name": "PIK3CA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYM3", "map_id": "F1MYM3", "name": "PIK3CB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009083", "map_id": "ENSBTAT00000009083", "name": "PIK3CB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23726", "map_id": "P23726", "name": "PIK3R2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003033", "map_id": "ENSBTAT00000003033", "name": "PIK3R2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065491", "map_id": "none", "name": "SOS mediated nucleotide exchange of RAS (SHC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040312", "map_id": "none", "name": "p21 RAS:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LKB7", "map_id": "A0A3Q1LKB7", "name": "HRAS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071009", "map_id": "ENSBTAT00000071009", "name": "HRAS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7R9", "map_id": "A5D7R9", "name": "NRAS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012897", "map_id": "ENSBTAT00000012897", "name": "NRAS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039728", "map_id": "none", "name": "p21 RAS:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10065488", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0IIE2", "map_id": "Q0IIE2", "name": "SHC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075224", "map_id": "ENSBTAT00000075224", "name": "SHC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7C3", "map_id": "F1N7C3", "name": "SOS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015471", "map_id": "ENSBTAT00000015471", "name": "SOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0F9", "map_id": "Q3T0F9", "name": "GRB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006216", "map_id": "ENSBTAT00000006216", "name": "GRB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040851", "map_id": "none", "name": "Connexin oligomerization in endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10040846", "map_id": "O18968", "name": "GJB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000027331", "map_id": "ENSBTAT00000027331", "name": "GJB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040848", "map_id": "none", "name": "Connexin 32 connexon", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O18968", "map_id": "O18968", "name": "GJB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049067", "map_id": "none", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane" }, { "id": "species_114565", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "false" }, { "id": "species_10049064", "map_id": "F1MUC1", "name": "LOC515333", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane", "complex": "false" }, { "id": "ENSBTAT00000013298", "map_id": "ENSBTAT00000013298", "name": "LOC515333", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051002", "map_id": "none", "name": "Release of platelet secretory granule components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10050998", "map_id": "G3X6N3", "name": "TF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "ENSBTAT00000009564", "map_id": "ENSBTAT00000009564", "name": "TF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051000", "map_id": "G3X6N3", "name": "TF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10050924", "map_id": "none", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050904", "map_id": "none", "name": "Platelet dense granule content", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "true" }, { "id": "A7E3W2", "map_id": "A7E3W2", "name": "LGALS3BP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001802", "map_id": "ENSBTAT00000001802", "name": "LGALS3BP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RS5", "map_id": "Q29RS5", "name": "RARRES2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084323", "map_id": "ENSBTAT00000084323", "name": "RARRES2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5Q6", "map_id": "A0A3Q1M5Q6", "name": "ECM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076112", "map_id": "ENSBTAT00000076112", "name": "ECM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKI3", "map_id": "A5PKI3", "name": "FAM3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073296", "map_id": "ENSBTAT00000073296", "name": "FAM3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29372", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "A0A452DIU4", "map_id": "A0A452DIU4", "name": "CLEC3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024391", "map_id": "ENSBTAT00000024391", "name": "CLEC3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTE4", "map_id": "A0A3Q1LTE4", "name": "CTSW", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080253", "map_id": "ENSBTAT00000080253", "name": "CTSW", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q27967", "map_id": "Q27967", "name": "phospho-SPP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002631", "map_id": "ENSBTAT00000002631", "name": "phospho-SPP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_111294", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "A6H754", "map_id": "A6H754", "name": "CDC37L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022777", "map_id": "ENSBTAT00000022777", "name": "CDC37L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050922", "map_id": "none", "name": "Platelet dense granule content", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10050994", "map_id": "none", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050980", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114510", "compartment_display": "platelet alpha granule membrane", "complex": "true" }, { "id": "F1MTN1", "map_id": "F1MTN1", "name": "phospho-ITGB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013173", "map_id": "ENSBTAT00000013173", "name": "phospho-ITGB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGZ4", "map_id": "F1MGZ4", "name": "ITGA2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010738", "map_id": "ENSBTAT00000010738", "name": "ITGA2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LI93", "map_id": "A0A3Q1LI93", "name": "CD109", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075662", "map_id": "ENSBTAT00000075662", "name": "CD109", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P26201", "map_id": "P26201", "name": "CD36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080828", "map_id": "ENSBTAT00000080828", "name": "CD36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MHJ9", "map_id": "A0A3Q1MHJ9", "name": "PECAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086833", "map_id": "ENSBTAT00000086833", "name": "PECAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PK28", "map_id": "A5PK28", "name": "LHFPL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067657", "map_id": "ENSBTAT00000067657", "name": "LHFPL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LEU1", "map_id": "A0A3Q1LEU1", "name": "phospho-APLP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081148", "map_id": "ENSBTAT00000081148", "name": "phospho-APLP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LN74", "map_id": "A0A3Q1LN74", "name": "SYTL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074339", "map_id": "ENSBTAT00000074339", "name": "SYTL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A1L6ZA12", "map_id": "A0A1L6ZA12", "name": "ly6g6f", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087233", "map_id": "ENSBTAT00000087233", "name": "ly6g6f", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050992", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050948", "map_id": "none", "name": "Surface deployment of platelet dense granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050938", "map_id": "none", "name": "Platelet dense granule membrane components", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane", "complex": "true" }, { "id": "Q8HZJ5", "map_id": "Q8HZJ5", "name": "RAB27B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078091", "map_id": "ENSBTAT00000078091", "name": "RAB27B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N8P4", "map_id": "A0A3Q1N8P4", "name": "LAMP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066443", "map_id": "ENSBTAT00000066443", "name": "LAMP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9XSK2", "map_id": "Q9XSK2", "name": "CD63", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015829", "map_id": "ENSBTAT00000015829", "name": "CD63", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050946", "map_id": "none", "name": "Platelet dense granule membrane components", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050870", "map_id": "none", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050802", "map_id": "none", "name": "Platelet alpha granule contents", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114506", "compartment_display": "platelet alpha granule lumen", "complex": "true" }, { "id": "A0A452DIX0", "map_id": "A0A452DIX0", "name": "PCYOX1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026577", "map_id": "ENSBTAT00000026577", "name": "PCYOX1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17697", "map_id": "P17697", "name": "CLU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007324", "map_id": "ENSBTAT00000007324", "name": "CLU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IF69", "map_id": "A4IF69", "name": "NHLRC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004806", "map_id": "ENSBTAT00000004806", "name": "NHLRC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MY12", "map_id": "F1MY12", "name": "phospho-LOC112442231", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016092", "map_id": "ENSBTAT00000016092", "name": "phospho-LOC112442231", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A140T8C8", "map_id": "A0A140T8C8", "name": "phospho-KNG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053071", "map_id": "ENSBTAT00000053071", "name": "phospho-KNG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A0A0MP92", "map_id": "A0A0A0MP92", "name": "SERPINA3-7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011576", "map_id": "ENSBTAT00000011576", "name": "SERPINA3-7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C4PU73", "map_id": "C4PU73", "name": "LOC286871", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009718", "map_id": "ENSBTAT00000009718", "name": "LOC286871", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A0A0MPA0", "map_id": "A0A0A0MPA0", "name": "LOC784932", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038516", "map_id": "ENSBTAT00000038516", "name": "LOC784932", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N1U4", "map_id": "G3N1U4", "name": "SERPINA3-3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064475", "map_id": "ENSBTAT00000064475", "name": "SERPINA3-3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGZ6", "map_id": "A0A3Q1MGZ6", "name": "LOC112445741", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077453", "map_id": "ENSBTAT00000077453", "name": "LOC112445741", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A0A0MP89", "map_id": "A0A0A0MP89", "name": "SERPINA3-8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009261", "map_id": "ENSBTAT00000009261", "name": "SERPINA3-8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJK6", "map_id": "A0A452DJK6", "name": "SERPINA3-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064935", "map_id": "ENSBTAT00000064935", "name": "SERPINA3-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMJ0", "map_id": "E1BMJ0", "name": "SERPING1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021638", "map_id": "ENSBTAT00000021638", "name": "SERPING1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9XS50", "map_id": "Q9XS50", "name": "VEGFC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019613", "map_id": "ENSBTAT00000019613", "name": "VEGFC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N9Y5", "map_id": "A0A3Q1N9Y5", "name": "phospho-QSOX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085713", "map_id": "ENSBTAT00000085713", "name": "phospho-QSOX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28800", "map_id": "P28800", "name": "SERPINF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027793", "map_id": "ENSBTAT00000027793", "name": "SERPINF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34955", "map_id": "P34955", "name": "phospho-SERPINA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072441", "map_id": "ENSBTAT00000072441", "name": "phospho-SERPINA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0A3", "map_id": "Q3T0A3", "name": "CFD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063284", "map_id": "ENSBTAT00000063284", "name": "CFD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP91", "map_id": "A6QP91", "name": "TGFB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015925", "map_id": "ENSBTAT00000015925", "name": "TGFB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBY0", "map_id": "E1BBY0", "name": "LEFTY2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000051964", "map_id": "ENSBTAT00000051964", "name": "LEFTY2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B726", "map_id": "E1B726", "name": "PLG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001674", "map_id": "ENSBTAT00000001674", "name": "PLG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIJ9", "map_id": "A0A452DIJ9", "name": "SERPINE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019232", "map_id": "ENSBTAT00000019232", "name": "SERPINE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7J5", "map_id": "G3X7J5", "name": "TOR4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032623", "map_id": "ENSBTAT00000032623", "name": "TOR4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MD83", "map_id": "F1MD83", "name": "PPBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015874", "map_id": "ENSBTAT00000015874", "name": "PPBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5GN72", "map_id": "Q5GN72", "name": "agp", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022991", "map_id": "ENSBTAT00000022991", "name": "agp", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2H1", "map_id": "A0A3Q1M2H1", "name": "MMRN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067311", "map_id": "ENSBTAT00000067311", "name": "MMRN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QL4", "map_id": "Q17QL4", "name": "MAGED2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007016", "map_id": "ENSBTAT00000007016", "name": "MAGED2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFA6", "map_id": "A4IFA6", "name": "ISLR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007913", "map_id": "ENSBTAT00000007913", "name": "ISLR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0I3", "map_id": "F1N0I3", "name": "phospho-F5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023573", "map_id": "ENSBTAT00000023573", "name": "phospho-F5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPG8", "map_id": "A0A3Q1LPG8", "name": "TEX264", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083114", "map_id": "ENSBTAT00000083114", "name": "TEX264", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5W1", "map_id": "G5E5W1", "name": "F8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036726", "map_id": "ENSBTAT00000036726", "name": "F8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P12763", "map_id": "P12763", "name": "phospho-AHSG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000673", "map_id": "ENSBTAT00000000673", "name": "phospho-AHSG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX05", "map_id": "F1MX05", "name": "SCCPDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004949", "map_id": "ENSBTAT00000004949", "name": "SCCPDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G8JKY5", "map_id": "G8JKY5", "name": "TMSB4X", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024387", "map_id": "ENSBTAT00000024387", "name": "TMSB4X", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMG1", "map_id": "A0A3Q1LMG1", "name": "ALDOA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083687", "map_id": "ENSBTAT00000083687", "name": "ALDOA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJ33", "map_id": "Q2HJ33", "name": "OLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009160", "map_id": "ENSBTAT00000009160", "name": "OLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07455", "map_id": "P07455", "name": "IGF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014713", "map_id": "ENSBTAT00000014713", "name": "IGF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050868", "map_id": "none", "name": "Platelet alpha granule contents", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10051062", "map_id": "none", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051036", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MHC2", "map_id": "F1MHC2", "name": "STXBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012094", "map_id": "ENSBTAT00000012094", "name": "STXBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P80513", "map_id": "P80513", "name": "MANF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045083", "map_id": "ENSBTAT00000045083", "name": "MANF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P63258", "map_id": "P63258", "name": "ACTG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008132", "map_id": "ENSBTAT00000008132", "name": "ACTG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRZ8", "map_id": "F1MRZ8", "name": "PLEK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012724", "map_id": "ENSBTAT00000012724", "name": "PLEK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MLQ7", "map_id": "A0A3Q1MLQ7", "name": "TLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074863", "map_id": "ENSBTAT00000074863", "name": "TLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YY77", "map_id": "A7YY77", "name": "ENDOD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034535", "map_id": "ENSBTAT00000034535", "name": "ENDOD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MNQ4", "map_id": "F1MNQ4", "name": "2xHC-SOD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039344", "map_id": "ENSBTAT00000039344", "name": "2xHC-SOD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LP13", "map_id": "A0A3Q1LP13", "name": "ANXA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075491", "map_id": "ENSBTAT00000075491", "name": "ANXA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8Z0", "map_id": "E1B8Z0", "name": "BRPF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079099", "map_id": "ENSBTAT00000079099", "name": "BRPF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9F5", "map_id": "Q5E9F5", "name": "TAGLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080925", "map_id": "ENSBTAT00000080925", "name": "TAGLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051060", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090306", "map_id": "none", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090272", "map_id": "none", "name": "RHOU:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5D7J5", "map_id": "A5D7J5", "name": "RHOU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024876", "map_id": "ENSBTAT00000024876", "name": "RHOU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090302", "map_id": "none", "name": "RHOU effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MWY5", "map_id": "F1MWY5", "name": "ARHGAP30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023764", "map_id": "ENSBTAT00000023764", "name": "ARHGAP30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H720", "map_id": "A6H720", "name": "NCK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069542", "map_id": "ENSBTAT00000069542", "name": "NCK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E52", "map_id": "Q08E52", "name": "PAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080749", "map_id": "ENSBTAT00000080749", "name": "PAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QZ0", "map_id": "Q17QZ0", "name": "PAK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086158", "map_id": "ENSBTAT00000086158", "name": "PAK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090304", "map_id": "none", "name": "RHOU:GTP:RHOU effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090311", "map_id": "none", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090308", "map_id": "none", "name": "RHOU:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10081497", "map_id": "none", "name": "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803743", "map_id": "CHEBI:88130", "name": "GlcNGc-6-P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_193473", "map_id": "CHEBI:16359", "name": "CCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449701", "map_id": "CHEBI:15873", "name": "GlcN6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10081494", "map_id": "A7MBC0", "name": "AMDHD2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000074115", "map_id": "ENSBTAT00000074115", "name": "AMDHD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050153", "map_id": "none", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29512", "map_id": "CHEBI:57634", "name": "Fru(6)P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29472", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29404", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050150", "map_id": "none", "name": "GFPT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZY2", "map_id": "F1MZY2", "name": "GFPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023441", "map_id": "ENSBTAT00000023441", "name": "GFPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHW0", "map_id": "A0A452DHW0", "name": "GFPT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002867", "map_id": "ENSBTAT00000002867", "name": "GFPT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081490", "map_id": "none", "name": "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803785", "map_id": "none", "name": "GlcNAc, GlcNGc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:27459", "map_id": "CHEBI:27459", "name": "CHEBI:27459", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1678743", "map_id": "CHEBI:17411", "name": "GlcNAc", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_6803738", "map_id": "none", "name": "GlcNAc-6-P, GlcNGc-6-P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_449703", "map_id": "CHEBI:15784", "name": "AcGlcN6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10081487", "map_id": "none", "name": "NAGK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DJF8", "map_id": "A0A452DJF8", "name": "NAGK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019528", "map_id": "ENSBTAT00000019528", "name": "NAGK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049778", "map_id": "none", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532204", "map_id": "CHEBI:7125", "name": "AcGlcN1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049775", "map_id": "A0A3Q1LP83", "name": "PGM3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000086526", "map_id": "ENSBTAT00000086526", "name": "PGM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069593", "map_id": "none", "name": "SMURF1/2 ubiquitinates PRICKLE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033408", "map_id": "none", "name": "Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10069585", "map_id": "A0A3Q1LMK1", "name": "PRICKLE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072372", "map_id": "ENSBTAT00000072372", "name": "PRICKLE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069588", "map_id": "A0A3Q1LMK1", "name": "PRICKLE1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069590", "map_id": "none", "name": "PARD6A:pp-DVL2:SMURF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6RHP0", "map_id": "F6RHP0", "name": "PARD6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032504", "map_id": "ENSBTAT00000032504", "name": "PARD6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSZ4", "map_id": "A0A3Q1MSZ4", "name": "phospho-DVL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078307", "map_id": "ENSBTAT00000078307", "name": "phospho-DVL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLS5", "map_id": "F1MLS5", "name": "SMURF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043725", "map_id": "ENSBTAT00000043725", "name": "SMURF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069595", "map_id": "none", "name": "SMURF1/2 are recruited to the DVL2:PARD6A complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069581", "map_id": "none", "name": "PARD6A:pp-DVL2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10042973", "map_id": "F1MLS5", "name": "SMURF1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10069872", "map_id": "none", "name": "WNT5A binding to FZD promotes PRICKLE1 degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069868", "map_id": "none", "name": "WNT5A-binding FZDs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MGM1", "map_id": "F1MGM1", "name": "FZD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027911", "map_id": "ENSBTAT00000027911", "name": "FZD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067196", "map_id": "E1BDG5", "name": "WNT5A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000026930", "map_id": "ENSBTAT00000026930", "name": "WNT5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069870", "map_id": "none", "name": "WNT5A:FZD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BDG5", "map_id": "E1BDG5", "name": "WNT5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044480", "map_id": "none", "name": "CYP4F3 20-hydroxylates LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_113534", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_156540", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_215557", "map_id": "CHEBI:15647", "name": "LTB4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113601", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113519", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113564", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_571314", "map_id": "CHEBI:15646", "name": "20OH-LTB4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044148", "map_id": "none", "name": "Cytochrome P450 (CYP4F2/4F3 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "M0QW30", "map_id": "M0QW30", "name": "CYP4F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072981", "map_id": "ENSBTAT00000072981", "name": "CYP4F2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCJ2", "map_id": "A0A3Q1MCJ2", "name": "LOC100295883", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073532", "map_id": "ENSBTAT00000073532", "name": "LOC100295883", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MU89", "map_id": "A0A3Q1MU89", "name": "CYP4F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCD3", "map_id": "F1MCD3", "name": "LOC509506", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036364", "map_id": "ENSBTAT00000036364", "name": "LOC509506", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071909", "map_id": "none", "name": "CYP4F22 20-hydroxylates TrXA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142713", "map_id": "CHEBI:15630", "name": "TrXA3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5602281", "map_id": "CHEBI:83782", "name": "20OH-TrXA3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035953", "map_id": "G3MZK4", "name": "LOC534967", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000066325", "map_id": "ENSBTAT00000066325", "name": "LOC534967", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044151", "map_id": "none", "name": "CYP4F2, 4F3 20-hydroxylate LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_266056", "map_id": "CHEBI:15647", "name": "LTB4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2161636", "map_id": "CHEBI:15646", "name": "20OH-LTB4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10073037", "map_id": "none", "name": "Activated FGFR4:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10035491", "map_id": "none", "name": "GRB2-1:SOS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073033", "map_id": "none", "name": "Activated FGFR4:pY-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N4S9", "map_id": "F1N4S9", "name": "KLB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019297", "map_id": "ENSBTAT00000019297", "name": "KLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN51", "map_id": "F1MN51", "name": "FGFR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013942", "map_id": "ENSBTAT00000013942", "name": "FGFR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFP8", "map_id": "E1BFP8", "name": "FGF19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022973", "map_id": "ENSBTAT00000022973", "name": "FGF19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_190915", "map_id": "CHEBI:28815", "name": "HS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "D8KXU9", "map_id": "D8KXU9", "name": "FGF9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064356", "map_id": "ENSBTAT00000064356", "name": "FGF9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03968", "map_id": "P03968", "name": "FGF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078959", "map_id": "ENSBTAT00000078959", "name": "FGF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3XGD3", "map_id": "G3XGD3", "name": "Fgf4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029946", "map_id": "ENSBTAT00000029946", "name": "Fgf4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXR4", "map_id": "G3MXR4", "name": "FGF17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065993", "map_id": "ENSBTAT00000065993", "name": "FGF17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHC1", "map_id": "E1BHC1", "name": "FGF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016675", "map_id": "ENSBTAT00000016675", "name": "FGF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BP37", "map_id": "E1BP37", "name": "FGF20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061318", "map_id": "ENSBTAT00000061318", "name": "FGF20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJU2", "map_id": "E1BJU2", "name": "FGF23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008940", "map_id": "ENSBTAT00000008940", "name": "FGF23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6G8", "map_id": "F1N6G8", "name": "FGF8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002001", "map_id": "ENSBTAT00000002001", "name": "FGF8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHC6", "map_id": "F1MHC6", "name": "FGF16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008839", "map_id": "ENSBTAT00000008839", "name": "FGF16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073035", "map_id": "none", "name": "Activated FGFR4:pY-SHC1:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073041", "map_id": "none", "name": "Activated FGFR4 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072995", "map_id": "Q0IIE2", "name": "SHC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065241", "map_id": "none", "name": "Activated FGFR4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073039", "map_id": "none", "name": "Activated FGFR4:SHC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073044", "map_id": "none", "name": "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073047", "map_id": "none", "name": "Activated FGFR4 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10076847", "map_id": "none", "name": "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_29870", "map_id": "CHEBI:15372", "name": "BH4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5696122", "map_id": "CHEBI:52575", "name": "alkylglycerol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1497857", "map_id": "CHEBI:15375", "name": "BH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76116", "map_id": "CHEBI:17754", "name": "Glycerol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5696116", "map_id": "CHEBI:35746", "name": "fatty aldehyde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076844", "map_id": "A0A3Q1NEB5", "name": "AGMO", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000069764", "map_id": "ENSBTAT00000069764", "name": "AGMO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035838", "map_id": "none", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75967", "map_id": "CHEBI:37554", "name": "FACoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76103", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_549167", "map_id": "CHEBI:17855", "name": "TAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76194", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035835", "map_id": "none", "name": "DGAT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MIW3", "map_id": "F1MIW3", "name": "DGAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037423", "map_id": "ENSBTAT00000037423", "name": "DGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035795", "map_id": "none", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76114", "map_id": "CHEBI:15978", "name": "G3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035790", "map_id": "Q0IID9", "name": "GK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000030932", "map_id": "ENSBTAT00000030932", "name": "GK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035829", "map_id": "none", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76108", "map_id": "CHEBI:29089", "name": "1,2-daG3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035826", "map_id": "none", "name": "LPIN1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LKP8", "map_id": "A0A3Q1LKP8", "name": "LPIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083005", "map_id": "ENSBTAT00000083005", "name": "LPIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV95", "map_id": "A0A3Q1LV95", "name": "LPIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067199", "map_id": "ENSBTAT00000067199", "name": "LPIN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080887", "map_id": "none", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6800352", "map_id": "CHEBI:17389", "name": "2AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1500578", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10080884", "map_id": "none", "name": "MOGAT1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q70VZ7", "map_id": "Q70VZ7", "name": "MOGAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011091", "map_id": "ENSBTAT00000011091", "name": "MOGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLQ3", "map_id": "F1MLQ3", "name": "MOGAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010395", "map_id": "ENSBTAT00000010395", "name": "MOGAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MYF6", "map_id": "G3MYF6", "name": "MOGAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064201", "map_id": "ENSBTAT00000064201", "name": "MOGAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090409", "map_id": "none", "name": "PRKCI phosphorylates ELF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090404", "map_id": "A5PJQ8", "name": "ELF3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000011536", "map_id": "ENSBTAT00000011536", "name": "ELF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090406", "map_id": "F1MQ96", "name": "PRKCI", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000061563", "map_id": "ENSBTAT00000061563", "name": "PRKCI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044826", "map_id": "none", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044815", "map_id": "none", "name": "Arf1-GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P84080", "map_id": "P84080", "name": "ARF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010159", "map_id": "ENSBTAT00000010159", "name": "ARF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044819", "map_id": "none", "name": "Arf1-GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10044823", "map_id": "E1BMC4", "name": "GBF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000061619", "map_id": "ENSBTAT00000061619", "name": "GBF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045538", "map_id": "none", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10045527", "map_id": "A0A452DIB2", "name": "STX4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000009899", "map_id": "ENSBTAT00000009899", "name": "STX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045525", "map_id": "A0A3Q1MED5", "name": "SNAP23", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000085048", "map_id": "ENSBTAT00000085048", "name": "SNAP23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045531", "map_id": "Q3T0Y8", "name": "VAMP8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "ENSBTAT00000033040", "map_id": "ENSBTAT00000033040", "name": "VAMP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045533", "map_id": "Q3T0Y8", "name": "VAMP8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10045535", "map_id": "none", "name": "Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T0Y8", "map_id": "Q3T0Y8", "name": "VAMP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MED5", "map_id": "A0A3Q1MED5", "name": "SNAP23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIB2", "map_id": "A0A452DIB2", "name": "STX4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034921", "map_id": "none", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111628", "map_id": "CHEBI:15859", "name": "N-carb-L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76630", "map_id": "CHEBI:17025", "name": "(S)-DHO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034918", "map_id": "none", "name": "CAD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MVC0", "map_id": "F1MVC0", "name": "CAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023783", "map_id": "ENSBTAT00000023783", "name": "CAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034924", "map_id": "none", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111647", "map_id": "CHEBI:17672", "name": "CAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29448", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10034927", "map_id": "none", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111627", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10048761", "map_id": "none", "name": "SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_109277", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_74113", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_83910", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048758", "map_id": "A0A3Q1MQ71", "name": "SLC34A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000084837", "map_id": "ENSBTAT00000084837", "name": "SLC34A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048754", "map_id": "none", "name": "SLC34A3 cotransports Pi, 2Na+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048751", "map_id": "A0A3Q1N3R7", "name": "SLC34A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000069253", "map_id": "ENSBTAT00000069253", "name": "SLC34A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065819", "map_id": "none", "name": "DCN (decorin) degradation by MMP2, MMP3, MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065294", "map_id": "P21793", "name": "DCN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000004562", "map_id": "ENSBTAT00000004562", "name": "DCN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065814", "map_id": "P21793", "name": "DCN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10065812", "map_id": "P21793", "name": "DCN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10065816", "map_id": "none", "name": "MMP2, MMP3, MMP7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MU56", "map_id": "F1MU56", "name": "MMP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006029", "map_id": "ENSBTAT00000006029", "name": "MMP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTX6", "map_id": "F1MTX6", "name": "MMP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013124", "map_id": "ENSBTAT00000013124", "name": "MMP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059674", "map_id": "none", "name": "Elastin degradation by elastin-degrading extracellular proteinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059657", "map_id": "none", "name": "Elastin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1MEV3", "map_id": "A0A3Q1MEV3", "name": "ELN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068399", "map_id": "ENSBTAT00000068399", "name": "ELN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10059665", "map_id": "none", "name": "Cleaved elastin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10059671", "map_id": "none", "name": "Elastin-degrading extracellular proteinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M4A6", "map_id": "A0A3Q1M4A6", "name": "MMP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081947", "map_id": "ENSBTAT00000081947", "name": "MMP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWP1", "map_id": "G3MWP1", "name": "ELANE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064480", "map_id": "ENSBTAT00000064480", "name": "ELANE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087324", "map_id": "none", "name": "MMP7 cleaves OPTC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10087311", "map_id": "P58874", "name": "OPTC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000018286", "map_id": "ENSBTAT00000018286", "name": "OPTC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087319", "map_id": "P58874", "name": "OPTC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10087317", "map_id": "P58874", "name": "OPTC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10087315", "map_id": "P58874", "name": "OPTC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10087321", "map_id": "P58874", "name": "OPTC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10058184", "map_id": "F1MU56", "name": "MMP7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10064649", "map_id": "none", "name": "Collagen type XIII ectodomain shedding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10064303", "map_id": "none", "name": "Collagen type XIII", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6RND5", "map_id": "F6RND5", "name": "COL13A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039811", "map_id": "ENSBTAT00000039811", "name": "COL13A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064625", "map_id": "F6RND5", "name": "COL13A1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10064623", "map_id": "none", "name": "Cleaved collagen type XIII", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10076984", "map_id": "none", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696409", "map_id": "CHEBI:16752", "name": "5PHL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113548", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693978", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113556", "map_id": "CHEBI:17917", "name": "2AMAS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076981", "map_id": "none", "name": "PXLP-K278-PHYKPL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1B8R9", "map_id": "E1B8R9", "name": "PHYKPL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018115", "map_id": "ENSBTAT00000018115", "name": "PHYKPL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059533", "map_id": "none", "name": "Collagen type IV degradation by MMP2,3,4,9,10,12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059526", "map_id": "none", "name": "Collagen type IV alpha1.alpha2.alpha5.alpha6 network", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LLV2", "map_id": "A0A3Q1LLV2", "name": "COL4A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083510", "map_id": "ENSBTAT00000083510", "name": "COL4A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NK51", "map_id": "A0A3Q1NK51", "name": "COL4A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083333", "map_id": "ENSBTAT00000083333", "name": "COL4A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M970", "map_id": "A0A3Q1M970", "name": "COL4A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070553", "map_id": "ENSBTAT00000070553", "name": "COL4A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10058166", "map_id": "none", "name": "Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10059530", "map_id": "none", "name": "MMP2,3,4,9,10,12", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10059598", "map_id": "none", "name": "Collagen type V degradation by MMP2,9,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058699", "map_id": "none", "name": "Collagen V", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "G3MZI7", "map_id": "G3MZI7", "name": "COL5A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063052", "map_id": "ENSBTAT00000063052", "name": "COL5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDT9", "map_id": "A0A3Q1MDT9", "name": "COL5A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084344", "map_id": "ENSBTAT00000084344", "name": "COL5A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJQ6", "map_id": "F1MJQ6", "name": "COL5A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013440", "map_id": "ENSBTAT00000013440", "name": "COL5A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10059595", "map_id": "none", "name": "Cleaved collagen type V fibril", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10059528", "map_id": "F1MTX6", "name": "MMP3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10058561", "map_id": "none", "name": "Collagen type II degradation by MMP1,3,8,13,PRSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058552", "map_id": "none", "name": "Collagen type II fibril", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P02459", "map_id": "P02459", "name": "COL2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017505", "map_id": "ENSBTAT00000017505", "name": "COL2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057938", "map_id": "none", "name": "Cleaved collagen type II fibril", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10058558", "map_id": "none", "name": "MMP1,3,8,13, PRSS2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MT97", "map_id": "F1MT97", "name": "MMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021014", "map_id": "ENSBTAT00000021014", "name": "MMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N0J0", "map_id": "G3N0J0", "name": "MMP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063400", "map_id": "ENSBTAT00000063400", "name": "MMP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWU9", "map_id": "A7YWU9", "name": "PRSS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028731", "map_id": "ENSBTAT00000028731", "name": "PRSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059441", "map_id": "none", "name": "Collagen type VI degradation by MMP2,9,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059282", "map_id": "none", "name": "Collagen type VI fibril", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BI98", "map_id": "E1BI98", "name": "COL6A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015668", "map_id": "ENSBTAT00000015668", "name": "COL6A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKG2", "map_id": "F1MKG2", "name": "COL6A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025663", "map_id": "ENSBTAT00000025663", "name": "COL6A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB91", "map_id": "E1BB91", "name": "COL6A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018479", "map_id": "ENSBTAT00000018479", "name": "COL6A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10059434", "map_id": "none", "name": "Cleaved collagen type VI fibril", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10059438", "map_id": "F1MMD4", "name": "MMP11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000008025", "map_id": "ENSBTAT00000008025", "name": "MMP11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064705", "map_id": "none", "name": "Collagen type XV restin release", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064651", "map_id": "none", "name": "Collagen type XV multimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M0N0", "map_id": "A0A3Q1M0N0", "name": "COL15A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072268", "map_id": "ENSBTAT00000072268", "name": "COL15A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064677", "map_id": "A0A3Q1M0N0", "name": "COL15A1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10064703", "map_id": "none", "name": "Cleaved collagen type XV multimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10058193", "map_id": "none", "name": "Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058168", "map_id": "none", "name": "Cleaved collagen fibrils", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A7E303", "map_id": "A7E303", "name": "COL8A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018159", "map_id": "ENSBTAT00000018159", "name": "COL8A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJR6", "map_id": "F1MJR6", "name": "COL8A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083731", "map_id": "ENSBTAT00000083731", "name": "COL8A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10058190", "map_id": "none", "name": "MMP1-3, 7-9, 12, 13", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10059651", "map_id": "none", "name": "Collagen type VIII degradation by MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059648", "map_id": "none", "name": "Collagen type VIII fibril", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10058052", "map_id": "none", "name": "Cleaved collagen type VIII fibril", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10058172", "map_id": "F1MT97", "name": "MMP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10059689", "map_id": "none", "name": "Full activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059684", "map_id": "F1MT97", "name": "MMP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059686", "map_id": "none", "name": "MMP2,3,7,10,11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MMD4", "map_id": "F1MMD4", "name": "MMP11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059913", "map_id": "none", "name": "Initial activation of proMMP7 by trypsin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059733", "map_id": "F1MU56", "name": "MMP7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059908", "map_id": "F1MU56", "name": "MMP7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059906", "map_id": "F1MU56", "name": "MMP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059910", "map_id": "none", "name": "MMP7 initial activators", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10059787", "map_id": "none", "name": "Initial activation of proMMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059746", "map_id": "F1MTX6", "name": "MMP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059750", "map_id": "F1MTX6", "name": "MMP3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059748", "map_id": "F1MTX6", "name": "MMP3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059784", "map_id": "none", "name": "proMMP3 initial activators", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q2KJ63", "map_id": "Q2KJ63", "name": "KLKB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012503", "map_id": "ENSBTAT00000012503", "name": "KLKB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJB8", "map_id": "A5PJB8", "name": "CTRB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053990", "map_id": "ENSBTAT00000053990", "name": "CTRB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWU6", "map_id": "A7YWU6", "name": "CTRB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWD8", "map_id": "A0A3Q1LWD8", "name": "LOC100848132", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076474", "map_id": "ENSBTAT00000076474", "name": "LOC100848132", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059869", "map_id": "none", "name": "Activation of proMMP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059862", "map_id": "F1MTX6", "name": "MMP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059866", "map_id": "none", "name": "proMMP10 activators", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10059804", "map_id": "none", "name": "Activation of proMMP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059793", "map_id": "G3N0J0", "name": "MMP8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10058188", "map_id": "G3N0J0", "name": "MMP8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059801", "map_id": "none", "name": "proMMP8 initial activators", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q6H320", "map_id": "Q6H320", "name": "KLK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024677", "map_id": "ENSBTAT00000024677", "name": "KLK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059902", "map_id": "none", "name": "Autocatalytic activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059706", "map_id": "F1MT97", "name": "MMP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059899", "map_id": "F1MT97", "name": "MMP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10059918", "map_id": "none", "name": "Autocatalytic activation of MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058180", "map_id": "F1MTX6", "name": "MMP3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059915", "map_id": "F1MTX6", "name": "MMP3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10059744", "map_id": "none", "name": "Activation of proMMP7 by MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059735", "map_id": "F1MU56", "name": "MMP7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059741", "map_id": "none", "name": "MMP3, CTSK, CTSL2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P25975", "map_id": "P25975", "name": "CTSL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036427", "map_id": "ENSBTAT00000036427", "name": "CTSL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059731", "map_id": "none", "name": "Initial activation of proMMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059704", "map_id": "F1MT97", "name": "MMP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059708", "map_id": "F1MT97", "name": "MMP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059728", "map_id": "none", "name": "proMMP1 initial activators", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A6QPI9", "map_id": "A6QPI9", "name": "TPSB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009636", "map_id": "ENSBTAT00000009636", "name": "TPSB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAD2", "map_id": "E1BAD2", "name": "LOC505658", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054741", "map_id": "ENSBTAT00000054741", "name": "LOC505658", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8U1", "map_id": "E1B8U1", "name": "LOC100139881", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052512", "map_id": "ENSBTAT00000052512", "name": "LOC100139881", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIP7", "map_id": "E1BIP7", "name": "LOC540321", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011737", "map_id": "ENSBTAT00000011737", "name": "LOC540321", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059923", "map_id": "none", "name": "Autocatalytic activation of MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059920", "map_id": "F1MU56", "name": "MMP7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_1604783", "map_id": "none", "name": "Highly sulphated glycosaminoglycans", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:24505", "map_id": "CHEBI:24505", "name": "CHEBI:24505", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_444761", "map_id": "CHEBI:37397", "name": "CHS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10060003", "map_id": "none", "name": "MT-MMPs are sorted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10059897", "map_id": "none", "name": "MT-MMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "F1N797", "map_id": "F1N797", "name": "MMP16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061368", "map_id": "ENSBTAT00000061368", "name": "MMP16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060001", "map_id": "none", "name": "MT-MMPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10068885", "map_id": "none", "name": "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059693", "map_id": "F1MER7", "name": "HSPG2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000022744", "map_id": "ENSBTAT00000022744", "name": "HSPG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068874", "map_id": "F1MER7", "name": "HSPG2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10068872", "map_id": "F1MER7", "name": "HSPG2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10068882", "map_id": "none", "name": "BMP1, TLL1, TLL2, Cathepsin L1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MF35", "map_id": "F1MF35", "name": "TLL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015593", "map_id": "ENSBTAT00000015593", "name": "TLL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEV7", "map_id": "E1BEV7", "name": "BMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001218", "map_id": "ENSBTAT00000001218", "name": "BMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DK38", "map_id": "A0A452DK38", "name": "CTSL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0X6", "map_id": "F1N0X6", "name": "TLL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007834", "map_id": "ENSBTAT00000007834", "name": "TLL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065751", "map_id": "none", "name": "Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10063837", "map_id": "none", "name": "Fibrillin 1,2,(3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MTZ4", "map_id": "F1MTZ4", "name": "FBN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020360", "map_id": "ENSBTAT00000020360", "name": "FBN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065748", "map_id": "none", "name": "Cleaved fibrillin 1,2,(3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10058176", "map_id": "A0A3Q1M4A6", "name": "MMP12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10087543", "map_id": "none", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10087535", "map_id": "A0A3Q1MG91", "name": "SCUBE3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068477", "map_id": "ENSBTAT00000068477", "name": "SCUBE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087541", "map_id": "none", "name": "SCUBE3 polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MG91", "map_id": "A0A3Q1MG91", "name": "SCUBE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059702", "map_id": "none", "name": "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059697", "map_id": "F1MER7", "name": "HSPG2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059695", "map_id": "F1MER7", "name": "HSPG2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10059699", "map_id": "none", "name": "MMP3, plasmin, (MMP12)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10061174", "map_id": "none", "name": "Cross-linking of FCGRIIA with IgG-coated Ag", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061170", "map_id": "F1MHH9", "name": "FCGR2B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000029116", "map_id": "ENSBTAT00000029116", "name": "FCGR2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039426", "map_id": "none", "name": "Antigen:IgG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N0V0", "map_id": "G3N0V0", "name": "IGHG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066155", "map_id": "ENSBTAT00000066155", "name": "IGHG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0K3", "map_id": "A0A3Q1M0K3", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085031", "map_id": "ENSBTAT00000085031", "name": "Ig heavy chain V-II region ARH-77", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M458", "map_id": "A0A3Q1M458", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M667", "map_id": "A0A3Q1M667", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFI7", "map_id": "A0A3Q1MFI7", "name": "LOC104968484", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081783", "map_id": "ENSBTAT00000081783", "name": "LOC104968484", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LKV0", "map_id": "A0A3Q1LKV0", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LLT0", "map_id": "A0A3Q1LLT0", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N188", "map_id": "G3N188", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N1H5", "map_id": "G3N1H5", "name": "LOC100300716", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064325", "map_id": "ENSBTAT00000064325", "name": "LOC100300716", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N3Q3", "map_id": "G3N3Q3", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MI29", "map_id": "A0A3Q1MI29", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ML26", "map_id": "A0A3Q1ML26", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXG6", "map_id": "G3MXG6", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N148", "map_id": "G3N148", "name": "Ig heavy chain V-II region ARH-77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10061172", "map_id": "none", "name": "IgG-Ag:FCGRIIA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MHH9", "map_id": "F1MHH9", "name": "FCGR2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033690", "map_id": "none", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113552", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_30471", "map_id": "CHEBI:17533", "name": "NAcGlu", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033687", "map_id": "E1BMR7", "name": "NAGS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000021616", "map_id": "ENSBTAT00000021616", "name": "NAGS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_374064", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10033706", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29468", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29514", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29498", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033703", "map_id": "none", "name": "ARG1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2KJ64", "map_id": "Q2KJ64", "name": "ARG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016461", "map_id": "ENSBTAT00000016461", "name": "ARG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033770", "map_id": "none", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113567", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113585", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29968", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033767", "map_id": "none", "name": "Mitochondrial ornithine transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q2KHW4", "map_id": "Q2KHW4", "name": "SLC25A15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015468", "map_id": "ENSBTAT00000015468", "name": "SLC25A15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1S4", "map_id": "A0A3Q1N1S4", "name": "SLC25A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015847", "map_id": "ENSBTAT00000015847", "name": "SLC25A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033697", "map_id": "none", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113561", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29896", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113581", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29676", "map_id": "CHEBI:17672", "name": "CAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033694", "map_id": "F1ML89", "name": "CPS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000022158", "map_id": "ENSBTAT00000022158", "name": "CPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084008", "map_id": "none", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083994", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA6 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2TA10", "map_id": "Q2TA10", "name": "UBE2D1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055368", "map_id": "ENSBTAT00000055368", "name": "UBE2D1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5N0", "map_id": "A0A3Q1M5N0", "name": "UBE2D3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066609", "map_id": "ENSBTAT00000066609", "name": "UBE2D3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083992", "map_id": "none", "name": "Ub-Cys625-UBA6:ubiquitin adenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1ME38", "map_id": "F1ME38", "name": "UBA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008985", "map_id": "ENSBTAT00000008985", "name": "UBA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084006", "map_id": "none", "name": "Ub:E2 (UBA6 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10083996", "map_id": "none", "name": "UBA6:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084122", "map_id": "none", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084119", "map_id": "P0CG53", "name": "UBB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033406", "map_id": "P0CG53", "name": "UBB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033404", "map_id": "P0CG53", "name": "UBB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033402", "map_id": "P0CG53", "name": "UBB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075812", "map_id": "F1N3P2", "name": "USP5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026356", "map_id": "ENSBTAT00000026356", "name": "USP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084113", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033394", "map_id": "A0A3Q1LU30", "name": "RPS27A(1-76)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034499", "map_id": "A0A3Q1LU30", "name": "RPS27A(77-156)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084110", "map_id": "none", "name": "UCHL3,USP7,USP9X", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N556", "map_id": "F1N556", "name": "USP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007177", "map_id": "ENSBTAT00000007177", "name": "USP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E630", "map_id": "G5E630", "name": "USP9X", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050390", "map_id": "ENSBTAT00000050390", "name": "USP9X", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084117", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084115", "map_id": "P63048", "name": "UBA52", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033398", "map_id": "P63048", "name": "UBA52", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034743", "map_id": "P63048", "name": "UBA52", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10086702", "map_id": "none", "name": "RNF181 binds BCL10 and Ubiquitin:E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_459", "compartment_display": "cytoplasm" }, { "id": "species_10086688", "map_id": "Q3T0W3", "name": "RNF181", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_459", "compartment_display": "cytoplasm", "complex": "false" }, { "id": "ENSBTAT00000024336", "map_id": "ENSBTAT00000024336", "name": "RNF181", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086698", "map_id": "none", "name": "Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1RMX2", "map_id": "Q1RMX2", "name": "UBE2D2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055723", "map_id": "ENSBTAT00000055723", "name": "UBE2D2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAR8", "map_id": "A0A3Q1MAR8", "name": "UBE2E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084854", "map_id": "ENSBTAT00000084854", "name": "UBE2E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043291", "map_id": "Q17QJ6", "name": "BCL10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000018398", "map_id": "ENSBTAT00000018398", "name": "BCL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086700", "map_id": "none", "name": "RNF181:BCL10:Ub:E2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_459", "compartment_display": "cytoplasm", "complex": "true" }, { "id": "Q17QJ6", "map_id": "Q17QJ6", "name": "BCL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0W3", "map_id": "Q3T0W3", "name": "RNF181", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086710", "map_id": "none", "name": "RNF181 polyubiquinates BCL10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_459", "compartment_display": "cytoplasm" }, { "id": "species_10086707", "map_id": "none", "name": "UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2N", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10086705", "map_id": "Q17QJ6", "name": "BCL10", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10047210", "map_id": "none", "name": "CHRM1,3,5 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045758", "map_id": "none", "name": "CHRM1,3,5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCK3", "map_id": "F1MCK3", "name": "CHRM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055896", "map_id": "ENSBTAT00000055896", "name": "CHRM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI80", "map_id": "A0A452DI80", "name": "CHRM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010601", "map_id": "ENSBTAT00000010601", "name": "CHRM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5C5", "map_id": "F1N5C5", "name": "CHRM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015383", "map_id": "ENSBTAT00000015383", "name": "CHRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_372533", "map_id": "CHEBI:15355", "name": "AcCho", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045760", "map_id": "none", "name": "CHRM1,3,5:AcCho", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047214", "map_id": "none", "name": "CHRM2,4 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046209", "map_id": "P41985", "name": "CHRM2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019534", "map_id": "ENSBTAT00000019534", "name": "CHRM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046211", "map_id": "none", "name": "CHRM2,CHRM4:AcCho", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P41985", "map_id": "P41985", "name": "CHRM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047224", "map_id": "none", "name": "D2D3,4 bind to DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_380873", "map_id": "CHEBI:18243", "name": "DA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046197", "map_id": "F1N454", "name": "DRD3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000002768", "map_id": "ENSBTAT00000002768", "name": "DRD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046199", "map_id": "none", "name": "DRD3,4:DA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N454", "map_id": "F1N454", "name": "DRD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091556", "map_id": "none", "name": "DRD2 binds DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10091552", "map_id": "F1N4I3", "name": "DRD2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014422", "map_id": "ENSBTAT00000014422", "name": "DRD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091554", "map_id": "none", "name": "DRD2:DA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N4I3", "map_id": "F1N4I3", "name": "DRD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047222", "map_id": "none", "name": "DRD1,5 bind DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047218", "map_id": "Q95136", "name": "DRD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000062955", "map_id": "ENSBTAT00000062955", "name": "DRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047220", "map_id": "none", "name": "DRD1,5:DA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q95136", "map_id": "Q95136", "name": "DRD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091929", "map_id": "none", "name": "HTR1A binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10091925", "map_id": "F6Q2H9", "name": "HTR1A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000054712", "map_id": "ENSBTAT00000054712", "name": "HTR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_114523", "map_id": "CHEBI:28790", "name": "5HT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10091927", "map_id": "none", "name": "HTR1A:5HT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6Q2H9", "map_id": "F6Q2H9", "name": "HTR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047256", "map_id": "none", "name": "5-HT4, 6 and 7 receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047252", "map_id": "none", "name": "HTR4,6,7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MLD1", "map_id": "A0A3Q1MLD1", "name": "HTR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067375", "map_id": "ENSBTAT00000067375", "name": "HTR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BE22", "map_id": "E1BE22", "name": "HTR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010513", "map_id": "ENSBTAT00000010513", "name": "HTR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD86", "map_id": "E1BD86", "name": "HTR7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011575", "map_id": "ENSBTAT00000011575", "name": "HTR7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047254", "map_id": "none", "name": "HTR4,6,7:5HT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047236", "map_id": "none", "name": "HTR1 and 5A receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046185", "map_id": "none", "name": "HTR1B,D,E,F,HTR5A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MMU1", "map_id": "F1MMU1", "name": "HTR1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054307", "map_id": "ENSBTAT00000054307", "name": "HTR1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MB93", "map_id": "F1MB93", "name": "HTR1E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037840", "map_id": "ENSBTAT00000037840", "name": "HTR1E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6R5F6", "map_id": "F6R5F6", "name": "HTR1F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052346", "map_id": "ENSBTAT00000052346", "name": "HTR1F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGM3", "map_id": "F1MGM3", "name": "HTR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061041", "map_id": "ENSBTAT00000061041", "name": "HTR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGY8", "map_id": "E1BGY8", "name": "HTR5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003759", "map_id": "ENSBTAT00000003759", "name": "HTR5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046187", "map_id": "none", "name": "HTR1B,D,E,F,HTR5A:5HT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047238", "map_id": "none", "name": "5-HT2 receptor can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045782", "map_id": "none", "name": "HTR2A-C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DIJ2", "map_id": "A0A452DIJ2", "name": "HTR2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017943", "map_id": "ENSBTAT00000017943", "name": "HTR2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QI78", "map_id": "F6QI78", "name": "HTR2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052796", "map_id": "ENSBTAT00000052796", "name": "HTR2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045784", "map_id": "none", "name": "HTR2A-C:5HT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047226", "map_id": "none", "name": "HRH4 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046191", "map_id": "E1BBS2", "name": "HRH4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000048201", "map_id": "ENSBTAT00000048201", "name": "HRH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_390899", "map_id": "CHEBI:18295", "name": "Hist", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046193", "map_id": "none", "name": "HRH4:Hist", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BBS2", "map_id": "E1BBS2", "name": "HRH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091825", "map_id": "none", "name": "HRH3 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10091821", "map_id": "F1MML8", "name": "HRH3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000020802", "map_id": "ENSBTAT00000020802", "name": "HRH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091823", "map_id": "none", "name": "HRH3:Hist", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MML8", "map_id": "F1MML8", "name": "HRH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047234", "map_id": "none", "name": "HRH2 binds hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047230", "map_id": "E1BK27", "name": "HRH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000061359", "map_id": "ENSBTAT00000061359", "name": "HRH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047232", "map_id": "none", "name": "HRH2:histamine", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BK27", "map_id": "E1BK27", "name": "HRH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090968", "map_id": "none", "name": "ADRB3 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_390627", "map_id": "none", "name": "ADR, NAd", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:28918", "map_id": "CHEBI:28918", "name": "CHEBI:28918", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051599", "map_id": "A0A3Q1MQZ8", "name": "ADRB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000085511", "map_id": "ENSBTAT00000085511", "name": "ADRB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051601", "map_id": "none", "name": "ADRB3:ADR,NAd", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MQZ8", "map_id": "A0A3Q1MQZ8", "name": "ADRB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090958", "map_id": "none", "name": "\u03b23-agonists:ADBR3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090923", "map_id": "none", "name": "ADRB1,2,3:\u03b2-blockers", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q28044", "map_id": "Q28044", "name": "phospho-ADRB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002779", "map_id": "ENSBTAT00000002779", "name": "phospho-ADRB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090925", "map_id": "none", "name": "-blockers bind ADRB1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9609307", "map_id": "none", "name": "\u03b2-blockers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10090921", "map_id": "none", "name": "ADRB1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047212", "map_id": "none", "name": "ADRA2A,B,C bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046203", "map_id": "A0A3Q1LQ48", "name": "ADRA2C", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065216", "map_id": "ENSBTAT00000065216", "name": "ADRA2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046205", "map_id": "none", "name": "ADRA2A,B,C:ADR,NAd", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LQ48", "map_id": "A0A3Q1LQ48", "name": "ADRA2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090960", "map_id": "none", "name": "3-agonists bind ADRB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9611836", "map_id": "none", "name": "\u03b23-agonists", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10090964", "map_id": "none", "name": "ADRB2 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10051593", "map_id": "Q28044", "name": "ADRB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10051595", "map_id": "none", "name": "ADRB2:ADR,NAd", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090962", "map_id": "none", "name": "\u03b21,2-agonists:ADBR1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047206", "map_id": "none", "name": "ADRA1A,B,D bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045770", "map_id": "none", "name": "ADRA1A,B,D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B7W0", "map_id": "E1B7W0", "name": "ADRA1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025981", "map_id": "ENSBTAT00000025981", "name": "ADRA1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGA6", "map_id": "F1MGA6", "name": "ADRA1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055443", "map_id": "ENSBTAT00000055443", "name": "ADRA1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045772", "map_id": "none", "name": "ADRA1A,B,D:ADR,NAd", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047204", "map_id": "none", "name": "\u03b11-agonists:ADRA1A,B,D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047202", "map_id": "none", "name": "\u03b11-antagonists:ADRA1A,B,D", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047332", "map_id": "none", "name": "Trace amine-associated receptors can bind trace amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047328", "map_id": "none", "name": "Trace amine-associated receptor", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N0G5", "map_id": "F1N0G5", "name": "TAAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054907", "map_id": "ENSBTAT00000054907", "name": "TAAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_391200", "map_id": "CHEBI:18397", "name": "PEA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10047330", "map_id": "none", "name": "Trace amine-associated receptor:PEA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083878", "map_id": "none", "name": "GPR143 binds L-Dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_8851314", "map_id": "CHEBI:15765", "name": "L-Dopa", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046122", "map_id": "G5E581", "name": "GPR143", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008485", "map_id": "ENSBTAT00000008485", "name": "GPR143", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046124", "map_id": "none", "name": "GPR143:L-Dopa", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E581", "map_id": "G5E581", "name": "GPR143", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038450", "map_id": "none", "name": "p-S295-PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30389", "map_id": "CHEBI:17489", "name": "cAMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10038447", "map_id": "E1BN64", "name": "phospho-PDE3B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000006874", "map_id": "ENSBTAT00000006874", "name": "phospho-PDE3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036570", "map_id": "none", "name": "PI3K-containing complexes phosphorylate PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036567", "map_id": "none", "name": "PI3K-containing complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MYE0", "map_id": "F1MYE0", "name": "phospho-IRS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028392", "map_id": "ENSBTAT00000028392", "name": "phospho-IRS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJE0", "map_id": "F1MJE0", "name": "IRS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015938", "map_id": "ENSBTAT00000015938", "name": "IRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VE24", "map_id": "A2VE24", "name": "FLT3LG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006962", "map_id": "ENSBTAT00000006962", "name": "FLT3LG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRU0", "map_id": "F1MRU0", "name": "phospho-FLT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024717", "map_id": "ENSBTAT00000024717", "name": "phospho-FLT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M864", "map_id": "A0A3Q1M864", "name": "phospho-GAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084533", "map_id": "ENSBTAT00000084533", "name": "phospho-GAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7I9", "map_id": "E1B7I9", "name": "FRS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025495", "map_id": "ENSBTAT00000025495", "name": "FRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPT9", "map_id": "A0A3Q1MPT9", "name": "FGFR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086336", "map_id": "ENSBTAT00000086336", "name": "FGFR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGY3", "map_id": "E1BGY3", "name": "FGF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011373", "map_id": "ENSBTAT00000011373", "name": "FGF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NAV6", "map_id": "A0A3Q1NAV6", "name": "FGF10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086367", "map_id": "ENSBTAT00000086367", "name": "FGF10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NNL0", "map_id": "A0A3Q1NNL0", "name": "FGF22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086016", "map_id": "ENSBTAT00000086016", "name": "FGF22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LUE0", "map_id": "A0A3Q1LUE0", "name": "FGFR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083788", "map_id": "ENSBTAT00000083788", "name": "FGFR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRU7", "map_id": "A0A3Q1LRU7", "name": "FGFR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072473", "map_id": "ENSBTAT00000072473", "name": "FGFR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAI2", "map_id": "E1BAI2", "name": "KL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018586", "map_id": "ENSBTAT00000018586", "name": "KL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3Q3", "map_id": "A0A3Q1M3Q3", "name": "FGF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073054", "map_id": "ENSBTAT00000073054", "name": "FGF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N339", "map_id": "F1N339", "name": "PTPN11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002653", "map_id": "ENSBTAT00000002653", "name": "PTPN11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036607", "map_id": "none", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036588", "map_id": "none", "name": "AKT2:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NH21", "map_id": "A0A3Q1NH21", "name": "phospho-AKT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076493", "map_id": "ENSBTAT00000076493", "name": "phospho-AKT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036604", "map_id": "none", "name": "p-T309,S474-AKT2:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036596", "map_id": "none", "name": "PDPK1:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MQJ7", "map_id": "F1MQJ7", "name": "PDPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039221", "map_id": "ENSBTAT00000039221", "name": "PDPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036590", "map_id": "none", "name": "AKT2 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036586", "map_id": "none", "name": "AKT2:THEM4,TRIB3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BA10", "map_id": "E1BA10", "name": "THEM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000020594", "map_id": "ENSBTAP00000020594", "name": "THEM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCE3", "map_id": "Q0VCE3", "name": "TRIB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022616", "map_id": "ENSBTAT00000022616", "name": "TRIB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036580", "map_id": "none", "name": "THEM4,TRIB3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10036598", "map_id": "none", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036594", "map_id": "F1MQJ7", "name": "PDPK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10035507", "map_id": "none", "name": "GRB2-1:SOS1 binds p-IRS1,p-IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035503", "map_id": "none", "name": "p-Y-IRS1,p-Y-IRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10035505", "map_id": "none", "name": "GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10035527", "map_id": "none", "name": "p-Y-IRS1,p-Y-IRS2 bind PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035523", "map_id": "none", "name": "PI3K", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10035525", "map_id": "none", "name": "p-Y-IRS1,p-Y-IRS2:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055817", "map_id": "none", "name": "Budding of COPII coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10055815", "map_id": "none", "name": "COPII vesicle with MHC class I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q3ZCC9", "map_id": "Q3ZCC9", "name": "SEC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023702", "map_id": "ENSBTAT00000023702", "name": "SEC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUW6", "map_id": "A0A3Q1MUW6", "name": "HLA class I histocompatibility antigen, alpha chain F precursor", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080813", "map_id": "ENSBTAT00000080813", "name": "HLA class I histocompatibility antigen, alpha chain F precursor", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BI37", "map_id": "E1BI37", "name": "BOLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035878", "map_id": "ENSBTAT00000035878", "name": "BOLA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZQ5", "map_id": "F1MZQ5", "name": "BOLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4Y5", "map_id": "F1N4Y5", "name": "BOLA-NC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021451", "map_id": "ENSBTAT00000021451", "name": "BOLA-NC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRW6", "map_id": "A0A3Q1LRW6", "name": "BOLA-A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080603", "map_id": "ENSBTAT00000080603", "name": "BOLA-A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MD45", "map_id": "A0A3Q1MD45", "name": "HLA class I histocompatibility antigen, alpha chain F precursor", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MG36", "map_id": "A0A3Q1MG36", "name": "JSP.1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082227", "map_id": "ENSBTAT00000082227", "name": "JSP.1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MIV3", "map_id": "A0A3Q1MIV3", "name": "LOC616942", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081596", "map_id": "ENSBTAT00000081596", "name": "LOC616942", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59080", "map_id": "CHEBI:59080", "name": "CHEBI:59080", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1236727", "map_id": "CHEBI:25676", "name": "Antigen peptide", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q3T0T7", "map_id": "Q3T0T7", "name": "SAR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028280", "map_id": "ENSBTAT00000028280", "name": "SAR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNT8", "map_id": "A6QNT8", "name": "SEC24A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043111", "map_id": "ENSBTAT00000043111", "name": "SEC24A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MV07", "map_id": "F1MV07", "name": "SEC24D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004721", "map_id": "ENSBTAT00000004721", "name": "SEC24D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVW5", "map_id": "F1MVW5", "name": "SEC23A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004831", "map_id": "ENSBTAT00000004831", "name": "SEC23A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055805", "map_id": "none", "name": "COPII vesicle with MHC class I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "reaction_10043659", "map_id": "none", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043655", "map_id": "none", "name": "SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043580", "map_id": "none", "name": "SAR1B:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10043657", "map_id": "none", "name": "SAR1B:GTP:SEC23:SEC24", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10055819", "map_id": "none", "name": "Capturing cargo and formation of prebudding complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10054858", "map_id": "none", "name": "Peptide bound class I MHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10055813", "map_id": "none", "name": "Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10055821", "map_id": "none", "name": "Expression of peptide bound class I MHC on cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10055781", "map_id": "none", "name": "Antigen peptide bound class I MHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10042061", "map_id": "none", "name": "Antigen peptide bound class I MHC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087807", "map_id": "none", "name": "Loading of antigenic peptides on to class I MHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane" }, { "id": "species_10055472", "map_id": "none", "name": "MHC:B2M peptide loading complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2NL04", "map_id": "Q2NL04", "name": "TAPBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022386", "map_id": "ENSBTAT00000022386", "name": "TAPBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9F1", "map_id": "Q5E9F1", "name": "BCAP31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068015", "map_id": "ENSBTAT00000068015", "name": "BCAP31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7J6", "map_id": "A5D7J6", "name": "CALR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020111", "map_id": "ENSBTAT00000020111", "name": "CALR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVY8", "map_id": "F1MVY8", "name": "TAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011787", "map_id": "ENSBTAT00000011787", "name": "TAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJS0", "map_id": "E1BJS0", "name": "TAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080751", "map_id": "ENSBTAT00000080751", "name": "TAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_983033", "map_id": "CHEBI:25676", "name": "Antigen peptide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10055474", "map_id": "none", "name": "Antigenic peptide:MHC:B2M peptide loading complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10054866", "map_id": "none", "name": "Transport of MHC heterotrimer to ER exit site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane" }, { "id": "species_10054864", "map_id": "none", "name": "Antigen peptide bound class I MHC:BAP31 oligomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10054862", "map_id": "none", "name": "BAP31 oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10055444", "map_id": "none", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_983032", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (8-16aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_983034", "map_id": "CHEBI:25676", "name": "oligopeptide fragment", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10055441", "map_id": "none", "name": "TAP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10055460", "map_id": "none", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_8943716", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10055457", "map_id": "F1MU34", "name": "ERAP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000078466", "map_id": "ENSBTAT00000078466", "name": "ERAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055783", "map_id": "none", "name": "Journey of cargo through Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane" }, { "id": "species_10055715", "map_id": "none", "name": "Antigen peptide bound class I MHC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "reaction_10039485", "map_id": "none", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10036954", "map_id": "none", "name": "G protein alpha:GTP complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N2V3", "map_id": "F1N2V3", "name": "GNA15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026624", "map_id": "ENSBTAT00000026624", "name": "GNA15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BA29", "map_id": "E1BA29", "name": "GNAQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016160", "map_id": "ENSBTAT00000016160", "name": "GNAQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037043", "map_id": "none", "name": "G-protein alpha:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036952", "map_id": "none", "name": "G-protein alpha (q/11/14/15)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037641", "map_id": "none", "name": "Caspase-8 activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037609", "map_id": "Q17QH5", "name": "BID", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000042737", "map_id": "ENSBTAT00000042737", "name": "BID", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037611", "map_id": "Q17QH5", "name": "BID", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037638", "map_id": "none", "name": "active caspase-8 ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2LGB8", "map_id": "Q2LGB8", "name": "CASP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075852", "map_id": "ENSBTAT00000075852", "name": "CASP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037731", "map_id": "none", "name": "Translocation of tBID to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037729", "map_id": "Q17QH5", "name": "BID", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037269", "map_id": "Q17QH5", "name": "BID", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10037618", "map_id": "none", "name": "Granzyme-B activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037615", "map_id": "F1MTF4", "name": "LOC508646", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000013262", "map_id": "ENSBTAT00000013262", "name": "LOC508646", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038007", "map_id": "none", "name": "Myristoylation of tBID by NMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038004", "map_id": "F1MZK0", "name": "NMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000007950", "map_id": "ENSBTAT00000007950", "name": "NMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049615", "map_id": "none", "name": "Receptor FFAR2 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046048", "map_id": "B9VJV9", "name": "GPR43", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008619", "map_id": "ENSBTAT00000008619", "name": "GPR43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_444210", "map_id": "none", "name": "FFAR2 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17120", "map_id": "CHEBI:17120", "name": "CHEBI:17120", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:31011", "map_id": "CHEBI:31011", "name": "CHEBI:31011", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_76179", "map_id": "CHEBI:30772", "name": "BUT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2022890", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "CHEBI:30768", "map_id": "CHEBI:30768", "name": "CHEBI:30768", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046050", "map_id": "none", "name": "FFAR2:FFAR2 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B9VJV9", "map_id": "B9VJV9", "name": "GPR43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049617", "map_id": "none", "name": "Receptor FFAR1 binds free fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_400427", "map_id": "none", "name": "FFAR1 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_426576", "map_id": "CHEBI:15756", "name": "PALM", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:50122", "map_id": "CHEBI:50122", "name": "CHEBI:50122", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_33549", "map_id": "CHEBI:30805", "name": "DDCX", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:16196", "map_id": "CHEBI:16196", "name": "CHEBI:16196", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:42504", "map_id": "CHEBI:42504", "name": "CHEBI:42504", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046042", "map_id": "G3MZT6", "name": "FFAR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000063172", "map_id": "ENSBTAT00000063172", "name": "FFAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046044", "map_id": "none", "name": "FFAR1:FFAR1 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MZT6", "map_id": "G3MZT6", "name": "FFAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049585", "map_id": "none", "name": "Receptor FFAR3 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046054", "map_id": "B9VJW0", "name": "GPR41", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000053502", "map_id": "ENSBTAT00000053502", "name": "GPR41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_444074", "map_id": "none", "name": "FFAR3 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10046056", "map_id": "none", "name": "FFAR3:FFAR3 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B9VJW0", "map_id": "B9VJW0", "name": "GPR41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067360", "map_id": "none", "name": "GPR31 is a receptor for 12(S)-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_3296298", "map_id": "CHEBI:34146", "name": "12(S)-HETE", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046489", "map_id": "F1N1J4", "name": "GPR31", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019274", "map_id": "ENSBTAT00000019274", "name": "GPR31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046491", "map_id": "none", "name": "GPR31:12(S)-HETE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N1J4", "map_id": "F1N1J4", "name": "GPR31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041453", "map_id": "none", "name": "VEGF-C,D bind to VEGFR3 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10041447", "map_id": "F1MHP5", "name": "FLT4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000040219", "map_id": "ENSBTAT00000040219", "name": "FLT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041443", "map_id": "none", "name": "VEGFC dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10041451", "map_id": "none", "name": "VEGFR3 dimer:VEGFC, VEGFD dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MHP5", "map_id": "F1MHP5", "name": "FLT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041463", "map_id": "none", "name": "VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10041457", "map_id": "F1MWF1", "name": "KDR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001038", "map_id": "ENSBTAT00000001038", "name": "KDR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041461", "map_id": "none", "name": "VEGFR2:VEGFA,C,D", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MWF1", "map_id": "F1MWF1", "name": "KDR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040328", "map_id": "none", "name": "Activation of SHP2 through the binding to phospho-Gab1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040231", "map_id": "F1N339", "name": "PTPN11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040245", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BBE2", "map_id": "E1BBE2", "name": "EREG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013571", "map_id": "ENSBTAT00000013571", "name": "EREG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7J4", "map_id": "A0A3Q1M7J4", "name": "TGFA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085129", "map_id": "ENSBTAT00000085129", "name": "TGFA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIN8", "map_id": "E1BIN8", "name": "HBEGF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029015", "map_id": "ENSBTAT00000029015", "name": "HBEGF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEV4", "map_id": "F1MEV4", "name": "AREG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024140", "map_id": "ENSBTAT00000024140", "name": "AREG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDM2", "map_id": "E1BDM2", "name": "EPGN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005295", "map_id": "ENSBTAT00000005295", "name": "EPGN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MHB0", "map_id": "A0A3Q1MHB0", "name": "phospho-EGFR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067365", "map_id": "ENSBTAT00000067365", "name": "phospho-EGFR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040247", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040299", "map_id": "none", "name": "SHP2 dephosphorylates Tyr 992 on EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040297", "map_id": "none", "name": "EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040267", "map_id": "none", "name": "Dephosphorylation of PAG by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040263", "map_id": "F1MQC1", "name": "phospho-PAG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000067689", "map_id": "ENSBTAT00000067689", "name": "PAG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040265", "map_id": "F1MQC1", "name": "PAG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10040254", "map_id": "none", "name": "Dephosphorylation of Gab1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040251", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040277", "map_id": "none", "name": "GAB1 phosphorylation by EGFR kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040271", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:GRB2:GAB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043129", "map_id": "none", "name": "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043120", "map_id": "none", "name": "WNT:FZD:LRP5/6:DVL:AXIN:GSK3B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BEN9", "map_id": "E1BEN9", "name": "WNT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020414", "map_id": "ENSBTAT00000020414", "name": "WNT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKL2", "map_id": "E1BKL2", "name": "WNT8A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035270", "map_id": "ENSBTAT00000035270", "name": "WNT8A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHG3", "map_id": "F1MHG3", "name": "WNT8B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017163", "map_id": "ENSBTAT00000017163", "name": "WNT8B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB15", "map_id": "A7MB15", "name": "FZD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002720", "map_id": "ENSBTAT00000002720", "name": "FZD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2W8", "map_id": "G3N2W8", "name": "FZD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027434", "map_id": "ENSBTAT00000027434", "name": "FZD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMW6", "map_id": "F1MMW6", "name": "phospho-DVL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025757", "map_id": "ENSBTAT00000025757", "name": "phospho-DVL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6M9", "map_id": "F1N6M9", "name": "phospho-DVL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014152", "map_id": "ENSBTAT00000014152", "name": "phospho-DVL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M5FK80", "map_id": "M5FK80", "name": "phospho-AXIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087508", "map_id": "ENSBTAT00000087508", "name": "phospho-AXIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIC3", "map_id": "F1MIC3", "name": "GSK3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056446", "map_id": "ENSBTAT00000056446", "name": "GSK3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043126", "map_id": "none", "name": "WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N1K8", "map_id": "F1N1K8", "name": "phospho-LRP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007756", "map_id": "ENSBTAT00000007756", "name": "phospho-LRP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071320", "map_id": "none", "name": "FRAT proteins bind GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041574", "map_id": "F1MIC3", "name": "GSK3B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041625", "map_id": "none", "name": "FRAT1,2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N174", "map_id": "G3N174", "name": "FRAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066153", "map_id": "ENSBTAT00000066153", "name": "FRAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNA0", "map_id": "E1BNA0", "name": "FRAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010458", "map_id": "ENSBTAT00000010458", "name": "FRAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041627", "map_id": "none", "name": "FRAT1,2:GSK3beta", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10059152", "map_id": "none", "name": "DVL recruits GSK3beta:AXIN1 to the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043061", "map_id": "none", "name": "GSK3B:AXIN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043118", "map_id": "none", "name": "WNT:FZD:LRP5/6:DVL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083835", "map_id": "none", "name": "KLK5 cleaves and activates KLK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_109276", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083828", "map_id": "E1BKC5", "name": "KLK8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000020127", "map_id": "ENSBTAT00000020127", "name": "KLK8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083830", "map_id": "E1BKC5", "name": "KLK8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083832", "map_id": "E1BKC5", "name": "KLK8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083733", "map_id": "E1BGD9", "name": "KLK5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000070524", "map_id": "ENSBTAT00000070524", "name": "KLK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083741", "map_id": "none", "name": "Dissociation of the SPINK5:KLK5 complex at low pH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083739", "map_id": "none", "name": "KLK5:SPINK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MJH0", "map_id": "F1MJH0", "name": "SPINK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025479", "map_id": "ENSBTAT00000025479", "name": "SPINK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGD9", "map_id": "E1BGD9", "name": "KLK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083737", "map_id": "F1MJH0", "name": "SPINK5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351626", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10083743", "map_id": "none", "name": "SPINK5(490-624) binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10083824", "map_id": "none", "name": "SPINK9 binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083820", "map_id": "A0A3Q1NK79", "name": "SPINK9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000081553", "map_id": "ENSBTAT00000081553", "name": "SPINK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083822", "map_id": "none", "name": "KLK5:SPINK9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1NK79", "map_id": "A0A3Q1NK79", "name": "SPINK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077943", "map_id": "none", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_171126", "map_id": "CHEBI:17855", "name": "TAGs", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_174675", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_6789319", "map_id": "CHEBI:33575", "name": "RCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10077940", "map_id": "none", "name": "keratinocyte LIPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BA50", "map_id": "E1BA50", "name": "LIPM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017778", "map_id": "ENSBTAT00000017778", "name": "LIPM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MVZ9", "map_id": "G3MVZ9", "name": "LIPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034704", "map_id": "ENSBTAT00000034704", "name": "LIPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084466", "map_id": "none", "name": "LINC01139 facilitates PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084458", "map_id": "none", "name": "HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BPU0", "map_id": "E1BPU0", "name": "LRRK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061570", "map_id": "ENSBTAT00000061570", "name": "LRRK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNA8", "map_id": "E1BNA8", "name": "PTK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061122", "map_id": "ENSBTAT00000061122", "name": "PTK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084463", "map_id": "none", "name": "HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090009", "map_id": "none", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090005", "map_id": "none", "name": "RHOD endosome effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MD15", "map_id": "A0A3Q1MD15", "name": "ANKFY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079650", "map_id": "ENSBTAT00000079650", "name": "ANKFY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089989", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "F1N7C7", "map_id": "F1N7C7", "name": "RHOD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027446", "map_id": "ENSBTAT00000027446", "name": "RHOD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090007", "map_id": "none", "name": "RHOD:GTP:RHOD endosome effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10091896", "map_id": "none", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10091892", "map_id": "none", "name": "RHOD mitochondrial outer membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MY55", "map_id": "F1MY55", "name": "PAK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023513", "map_id": "ENSBTAT00000023513", "name": "PAK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091882", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10091894", "map_id": "none", "name": "RHOD:GTP:RHOD mitochondrial outer membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10090011", "map_id": "none", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089969", "map_id": "none", "name": "RHOD:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091884", "map_id": "none", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091916", "map_id": "none", "name": "RHOD binds effectors at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10091900", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10091912", "map_id": "none", "name": "RHOD Golgi membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MZP2", "map_id": "A0A3Q1MZP2", "name": "FILIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081390", "map_id": "ENSBTAT00000081390", "name": "FILIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091914", "map_id": "none", "name": "RHOD:GTP:RHOD Golgi membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10091902", "map_id": "none", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10089985", "map_id": "none", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089965", "map_id": "none", "name": "RHOD:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10089982", "map_id": "none", "name": "RHOD GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6RWK1", "map_id": "F6RWK1", "name": "ARHGAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043933", "map_id": "ENSBTAT00000043933", "name": "ARHGAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B801", "map_id": "E1B801", "name": "ARHGAP35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085833", "map_id": "ENSBTAT00000085833", "name": "ARHGAP35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWV5", "map_id": "A0A3Q1LWV5", "name": "ARHGAP26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075058", "map_id": "ENSBTAT00000075058", "name": "ARHGAP26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089972", "map_id": "none", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091878", "map_id": "none", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091874", "map_id": "none", "name": "RHOD plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BAJ4", "map_id": "E1BAJ4", "name": "STBD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013713", "map_id": "ENSBTAT00000013713", "name": "STBD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7A0", "map_id": "A5D7A0", "name": "EFHD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044780", "map_id": "ENSBTAT00000044780", "name": "EFHD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79132", "map_id": "P79132", "name": "CAV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023751", "map_id": "ENSBTAT00000023751", "name": "CAV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNG7", "map_id": "A0A3Q1LNG7", "name": "LMNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075973", "map_id": "ENSBTAT00000075973", "name": "LMNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LR88", "map_id": "A0A3Q1LR88", "name": "CAPZB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066654", "map_id": "ENSBTAT00000066654", "name": "CAPZB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0JN43", "map_id": "A0JN43", "name": "ESYT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044160", "map_id": "ENSBTAT00000044160", "name": "ESYT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMN2", "map_id": "E1BMN2", "name": "DIAPH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061079", "map_id": "ENSBTAT00000061079", "name": "DIAPH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPT9", "map_id": "A0A3Q1LPT9", "name": "STEAP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077862", "map_id": "ENSBTAT00000077862", "name": "STEAP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NDE1", "map_id": "A0A3Q1NDE1", "name": "ADD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086993", "map_id": "ENSBTAT00000086993", "name": "ADD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSB2", "map_id": "A0A3Q1MSB2", "name": "AKAP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070687", "map_id": "ENSBTAT00000070687", "name": "AKAP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNB6", "map_id": "A0A3Q1LNB6", "name": "ARHGAP39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070608", "map_id": "ENSBTAT00000070608", "name": "ARHGAP39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHQ9", "map_id": "E1BHQ9", "name": "MCAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047009", "map_id": "ENSBTAT00000047009", "name": "MCAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091876", "map_id": "none", "name": "RHOD:GTP:RHOD plasma membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057177", "map_id": "none", "name": "SHC1 binds P-ERBB4 isoform dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057163", "map_id": "none", "name": "p-ERBB4 homodimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MKB4", "map_id": "A0A3Q1MKB4", "name": "phospho-ERBB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084727", "map_id": "ENSBTAT00000084727", "name": "phospho-ERBB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035544", "map_id": "Q0IIE2", "name": "SHC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057170", "map_id": "none", "name": "SHC1:p-ERBB4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057188", "map_id": "none", "name": "Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057172", "map_id": "none", "name": "p-Y349,350-SHC1:p-ERBB4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057186", "map_id": "none", "name": "GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057175", "map_id": "none", "name": "Phosphorylation of SHC1 by ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10057191", "map_id": "none", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10083712", "map_id": "none", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_548819", "map_id": "CHEBI:15514", "name": "AA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848483", "map_id": "CHEBI:17504", "name": "2-lysophosphatidylcholine", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_429785", "map_id": "CHEBI:16110", "name": "PC", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10083709", "map_id": "G5E5P6", "name": "AGPAT3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000087371", "map_id": "ENSBTAT00000087371", "name": "AGPAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083004", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10082997", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MWA3", "map_id": "A0A3Q1MWA3", "name": "RAB1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083281", "map_id": "ENSBTAT00000083281", "name": "RAB1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMC4", "map_id": "E1BMC4", "name": "GBF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV05", "map_id": "A0A3Q1LV05", "name": "ARF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074696", "map_id": "ENSBTAT00000074696", "name": "ARF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083001", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10083006", "map_id": "none", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10082022", "map_id": "E1BMC4", "name": "GBF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10082993", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10082995", "map_id": "none", "name": "RAB1:GTP:GBF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10082999", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10082034", "map_id": "none", "name": "ARF:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10049867", "map_id": "none", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_162860", "map_id": "CHEBI:15820", "name": "GDP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449293", "map_id": "CHEBI:18341", "name": "N,N'-DCDOLDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449283", "map_id": "CHEBI:18396", "name": "MDCDD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049864", "map_id": "F1N2J7", "name": "ALG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000002836", "map_id": "ENSBTAT00000002836", "name": "ALG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049851", "map_id": "none", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449737", "map_id": "CHEBI:59085", "name": "(GlcNAc)2 (Man)2 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049848", "map_id": "A4FUG6", "name": "ALG2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000003187", "map_id": "ENSBTAT00000003187", "name": "ALG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049789", "map_id": "none", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449229", "map_id": "CHEBI:15809", "name": "DOLP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449298", "map_id": "CHEBI:53022", "name": "(GlcNAc)2 (Man)5 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449311", "map_id": "CHEBI:16214", "name": "DOLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449315", "map_id": "CHEBI:53023", "name": "(GlcNAc)2 (Man)6 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049782", "map_id": "F6QW25", "name": "ALG3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000032212", "map_id": "ENSBTAT00000032212", "name": "ALG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049787", "map_id": "Q148D6", "name": "MPDU1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000000147", "map_id": "ENSBTAT00000000147", "name": "MPDU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049811", "map_id": "none", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449312", "map_id": "CHEBI:59088", "name": "(GlcNAc)2 (Man)7 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449365", "map_id": "CHEBI:59091", "name": "(GlcNAc)2 (Man)8 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049808", "map_id": "A5PJJ2", "name": "ALG12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000064352", "map_id": "ENSBTAT00000064352", "name": "ALG12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049858", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10049855", "map_id": "E1BA58", "name": "ALG9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000052671", "map_id": "ENSBTAT00000052671", "name": "ALG9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082941", "map_id": "none", "name": "NUDT14 hydrolyses UDP-Glc to G1P and UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29410", "map_id": "CHEBI:18066", "name": "UDP-Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29548", "map_id": "CHEBI:16077", "name": "G1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109402", "map_id": "CHEBI:16695", "name": "UMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10082938", "map_id": "Q05B60", "name": "NUDT14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000063951", "map_id": "ENSBTAT00000063951", "name": "NUDT14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077816", "map_id": "none", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787618", "map_id": "CHEBI:16955", "name": "GDP-DHDMan", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787646", "map_id": "CHEBI:86476", "name": "GDP-KDGal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077813", "map_id": "none", "name": "TSTA3 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M2A1", "map_id": "A0A3Q1M2A1", "name": "GFUS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082106", "map_id": "ENSBTAT00000082106", "name": "GFUS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077800", "map_id": "none", "name": "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787542", "map_id": "CHEBI:12387", "name": "Fuc1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_742368", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077797", "map_id": "E1B9U5", "name": "FPGT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000055149", "map_id": "ENSBTAT00000055149", "name": "FPGT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077823", "map_id": "none", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077820", "map_id": "Q3ZBY8", "name": "GMDS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000015992", "map_id": "ENSBTAT00000015992", "name": "GMDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077807", "map_id": "none", "name": "FUK phosphorylates beta-Fuc to Fuc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787678", "map_id": "CHEBI:42589", "name": "beta-Fuc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077804", "map_id": "A0A3Q1M4E5", "name": "FCSK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000085459", "map_id": "ENSBTAT00000085459", "name": "FCSK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077826", "map_id": "none", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10049831", "map_id": "none", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532562", "map_id": "CHEBI:17369", "name": "Man6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_532531", "map_id": "CHEBI:35374", "name": "Man1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049828", "map_id": "none", "name": "PMM1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC17", "map_id": "Q0VC17", "name": "PMM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076692", "map_id": "ENSBTAT00000076692", "name": "PMM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZJ9", "map_id": "Q3SZJ9", "name": "PMM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001888", "map_id": "ENSBTAT00000001888", "name": "PMM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069368", "map_id": "none", "name": "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_162756", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_110096", "map_id": "CHEBI:17659", "name": "UDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4085214", "map_id": "CHEBI:17122", "name": "ManNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069365", "map_id": "none", "name": "GNE hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MIL9", "map_id": "F1MIL9", "name": "GNE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001520", "map_id": "ENSBTAT00000001520", "name": "GNE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069320", "map_id": "none", "name": "NANS converts ManNAc-6-P to Neu5Ac-9-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_4085225", "map_id": "CHEBI:28273", "name": "ManNAc-6-P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29492", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4085390", "map_id": "CHEBI:27438", "name": "Neu5Ac-9-P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069317", "map_id": "Q1RMX7", "name": "NANS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025318", "map_id": "ENSBTAT00000025318", "name": "NANS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069371", "map_id": "none", "name": "GNE phosphorylates ManNAc to ManNAc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10069357", "map_id": "none", "name": "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428633", "map_id": "CHEBI:17012", "name": "Neu5Ac", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069354", "map_id": "none", "name": "NANP:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7YWM8", "map_id": "A7YWM8", "name": "NANP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000918", "map_id": "ENSBTAT00000000918", "name": "NANP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069373", "map_id": "none", "name": "NEU2 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_4088202", "map_id": "none", "name": "glycoconjugates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_4086294", "map_id": "CHEBI:75129", "name": "Neu5Ac-2,6-Gal-R", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4086341", "map_id": "CHEBI:62634", "name": "Neu5Ac-2,6-GalNAc-R", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4087982", "map_id": "CHEBI:75130", "name": "Neu5Ac-2,8-Neu5Ac-R", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4086277", "map_id": "CHEBI:75127", "name": "Neu5Ac-2,3-Gal-R", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4088123", "map_id": "none", "name": "Gal-R,GalNAc-R,Neu5Ac-R", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_4088006", "map_id": "CHEBI:75133", "name": "Neu5Ac-R", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4086285", "map_id": "CHEBI:61248", "name": "Gal-R", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_4086301", "map_id": "CHEBI:21507", "name": "GalNAc-R", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10059958", "map_id": "G5E5Q1", "name": "NEU2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000027552", "map_id": "ENSBTAT00000027552", "name": "NEU2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069359", "map_id": "none", "name": "NEU3 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_4088088", "map_id": "none", "name": "NEU3 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_4088103", "map_id": "none", "name": "Gal-R, Neu5Ac-R", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10059981", "map_id": "F1MRJ3", "name": "NEU3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000036738", "map_id": "ENSBTAT00000036738", "name": "NEU3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048958", "map_id": "none", "name": "SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_428040", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_428639", "map_id": "CHEBI:17012", "name": "Neu5Ac", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10048955", "map_id": "E1B7R3", "name": "SLC17A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "ENSBTAT00000061225", "map_id": "ENSBTAT00000061225", "name": "SLC17A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069329", "map_id": "none", "name": "ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_727815", "map_id": "CHEBI:16556", "name": "CMP-Neu5Ac", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_727810", "map_id": "CHEBI:17361", "name": "CMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10069326", "map_id": "none", "name": "ST8SIA1-6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1N8K2", "map_id": "A0A3Q1N8K2", "name": "ST8SIA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074715", "map_id": "ENSBTAT00000074715", "name": "ST8SIA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LM08", "map_id": "A0A3Q1LM08", "name": "ST8SIA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077891", "map_id": "ENSBTAT00000077891", "name": "ST8SIA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZS9", "map_id": "A0A3Q1LZS9", "name": "ST8SIA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068182", "map_id": "ENSBTAT00000068182", "name": "ST8SIA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051554", "map_id": "none", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_4085435", "map_id": "CHEBI:16556", "name": "CMP-Neu5Ac", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109395", "map_id": "CHEBI:17361", "name": "CMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051551", "map_id": "Q3SZP1", "name": "SLC35A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000018680", "map_id": "ENSBTAT00000018680", "name": "SLC35A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069346", "map_id": "none", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10069343", "map_id": "none", "name": "ST6GALNAC1-6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1MXN8", "map_id": "F1MXN8", "name": "ST6GALNAC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009616", "map_id": "ENSBTAT00000009616", "name": "ST6GALNAC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N3B2", "map_id": "G3N3B2", "name": "ST6GALNAC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063122", "map_id": "ENSBTAT00000063122", "name": "ST6GALNAC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJH9", "map_id": "A0A452DJH9", "name": "ST6GALNAC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061027", "map_id": "ENSBTAT00000061027", "name": "ST6GALNAC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRX1", "map_id": "A0A3Q1LRX1", "name": "ST6GALNAC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078008", "map_id": "ENSBTAT00000078008", "name": "ST6GALNAC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6V7", "map_id": "F1N6V7", "name": "ST6GALNAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034693", "map_id": "ENSBTAT00000034693", "name": "ST6GALNAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069348", "map_id": "none", "name": "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10054719", "map_id": "none", "name": "ST3GAL1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1LUC6", "map_id": "A0A3Q1LUC6", "name": "ST3GAL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078218", "map_id": "ENSBTAT00000078218", "name": "ST3GAL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGH3", "map_id": "A0A3Q1MGH3", "name": "ST3GAL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075324", "map_id": "ENSBTAT00000075324", "name": "ST3GAL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D960", "map_id": "A5D960", "name": "ST3GAL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001538", "map_id": "ENSBTAT00000001538", "name": "ST3GAL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6H8M9", "map_id": "Q6H8M9", "name": "siat4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086395", "map_id": "ENSBTAT00000086395", "name": "siat4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069382", "map_id": "none", "name": "ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10069379", "map_id": "none", "name": "ST6GAL1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1M347", "map_id": "A0A3Q1M347", "name": "ST6GAL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083430", "map_id": "ENSBTAT00000083430", "name": "ST6GAL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7T4", "map_id": "A5D7T4", "name": "ST6GAL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070130", "map_id": "ENSBTAT00000070130", "name": "ST6GAL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069498", "map_id": "none", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419981", "map_id": "CHEBI:67132", "name": "pPNOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449221", "map_id": "CHEBI:16091", "name": "DCHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10049818", "map_id": "none", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449744", "map_id": "CHEBI:15750", "name": "DOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449299", "map_id": "CHEBI:16214", "name": "DOLP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049815", "map_id": "F1MW49", "name": "DOLPP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000023834", "map_id": "ENSBTAT00000023834", "name": "DOLPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049804", "map_id": "none", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_110614", "map_id": "CHEBI:17677", "name": "CTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_110094", "map_id": "CHEBI:17239", "name": "CDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10049801", "map_id": "Q58CR4", "name": "DOLK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000014016", "map_id": "ENSBTAT00000014016", "name": "DOLK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040933", "map_id": "none", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191403", "map_id": "CHEBI:15899", "name": "MVA5PP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113528", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191362", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040930", "map_id": "none", "name": "MVD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0P570", "map_id": "Q0P570", "name": "MVD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015994", "map_id": "ENSBTAT00000015994", "name": "MVD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049797", "map_id": "none", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449222", "map_id": "CHEBI:18278", "name": "GlcNAcDOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10049794", "map_id": "A0A3Q1NJ62", "name": "DPAGT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000070574", "map_id": "ENSBTAT00000070574", "name": "DPAGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049844", "map_id": "none", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10049841", "map_id": "none", "name": "ALG13:ALG14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MU60", "map_id": "F1MU60", "name": "LOC107132045", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006020", "map_id": "ENSBTAT00000006020", "name": "LOC107132045", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MW72", "map_id": "A0A3Q1MW72", "name": "ALG14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076761", "map_id": "ENSBTAT00000076761", "name": "ALG14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049860", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449371", "map_id": "CHEBI:37637", "name": "(GlcNAc)2 (Man)9 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10056074", "map_id": "none", "name": "ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_975925", "map_id": "CHEBI:17012", "name": "Neu5Ac", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_975910", "map_id": "CHEBI:59520", "name": "NGP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_981615", "map_id": "none", "name": "Glycoprotein-Neu5Ac", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10056071", "map_id": "none", "name": "ST8SIA2,3,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10056061", "map_id": "none", "name": "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10054717", "map_id": "A0A3Q1MGH3", "name": "ST3GAL4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10054431", "map_id": "none", "name": "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_914003", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_981616", "map_id": "none", "name": "Glycoprotein with GlcNAc in position 4", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054428", "map_id": "none", "name": "MGAT4s", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BNB2", "map_id": "E1BNB2", "name": "MGAT4C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014809", "map_id": "ENSBTAT00000014809", "name": "MGAT4C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQ63", "map_id": "A6QQ63", "name": "MGAT4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049734", "map_id": "ENSBTAT00000049734", "name": "MGAT4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054467", "map_id": "none", "name": "Addition of galactose by beta 4-galactosyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_735682", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_981618", "map_id": "none", "name": "Glycoprotein with galactose", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054464", "map_id": "none", "name": "B4GALT1-6 homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F6RH18", "map_id": "F6RH18", "name": "B4GALT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047259", "map_id": "ENSBTAT00000047259", "name": "B4GALT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08037", "map_id": "P08037", "name": "B4GALT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020286", "map_id": "ENSBTAT00000020286", "name": "B4GALT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCQ2", "map_id": "E1BCQ2", "name": "B4GALT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061252", "map_id": "ENSBTAT00000061252", "name": "B4GALT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RJ53", "map_id": "F6RJ53", "name": "B4GALT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015761", "map_id": "ENSBTAT00000015761", "name": "B4GALT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054418", "map_id": "none", "name": "ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10054415", "map_id": "A0A3Q1M347", "name": "ST6GAL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10054438", "map_id": "none", "name": "Addition of GlcNAc to position 5 by MGAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_981617", "map_id": "none", "name": "Glycoprotein with GlcNAc in position 5", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054435", "map_id": "A0A3Q1LV92", "name": "MGAT5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000084669", "map_id": "ENSBTAT00000084669", "name": "MGAT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054474", "map_id": "none", "name": "Addition of a bifurcating GlcNAc to the N-glycan by MGAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_981613", "map_id": "none", "name": "Glycoprotein with bifurcating GlcNAc in position 3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054471", "map_id": "E1BJA5", "name": "MGAT3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000016591", "map_id": "ENSBTAT00000016591", "name": "MGAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054411", "map_id": "none", "name": "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_975819", "map_id": "CHEBI:60615", "name": "(GlcNAc)3 (Man)3 (Asn)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_205687", "map_id": "CHEBI:17659", "name": "UDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_975822", "map_id": "CHEBI:60651", "name": "(GlcNAc)4 (Man)3 (Asn)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054408", "map_id": "E1BB36", "name": "MGAT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000048092", "map_id": "ENSBTAT00000048092", "name": "MGAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076415", "map_id": "none", "name": "FUCA1 hydrolyses NGP:1,6-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1605715", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6784247", "map_id": "none", "name": "NGP:1,6-GlcNAc", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6784248", "map_id": "CHEBI:59520", "name": "NGP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6784249", "map_id": "CHEBI:2181", "name": "L-fucose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10076412", "map_id": "none", "name": "FUCA1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "Q2KIM0", "map_id": "Q2KIM0", "name": "FUCA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042970", "map_id": "ENSBTAT00000042970", "name": "FUCA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077710", "map_id": "none", "name": "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_741440", "map_id": "CHEBI:17980", "name": "PAPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10077694", "map_id": "none", "name": "glyco-Lutropin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10077703", "map_id": "none", "name": "S-glyco-Lutropin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_742343", "map_id": "CHEBI:17985", "name": "PAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10077707", "map_id": "C0LMH8", "name": "CHST8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000064164", "map_id": "ENSBTAT00000064164", "name": "CHST8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077717", "map_id": "none", "name": "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_6786371", "map_id": "CHEBI:86336", "name": "HNK1 carbohydrate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_6786380", "map_id": "CHEBI:86335", "name": "S-HNK1 carbohydrate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10077714", "map_id": "A0A3Q1M1B8", "name": "CHST10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000082120", "map_id": "ENSBTAT00000082120", "name": "CHST10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076422", "map_id": "none", "name": "FUT3 transfers L-fucose to Gal1,3GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_5693930", "map_id": "CHEBI:18915", "name": "Gal1,3GlcNAc group", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_205683", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_5693933", "map_id": "CHEBI:18914", "name": "Gal1,3Fuc1,4GlcNAc group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_205689", "map_id": "CHEBI:17552", "name": "GDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10076419", "map_id": "F1MBS8", "name": "FUT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000000529", "map_id": "ENSBTAT00000000529", "name": "FUT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076696", "map_id": "none", "name": "MIA2 binds PREB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10076692", "map_id": "A0A3Q1LM15", "name": "MIA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000078548", "map_id": "ENSBTAT00000078548", "name": "MIA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043646", "map_id": "E1BL12", "name": "PREB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000009307", "map_id": "ENSBTAT00000009307", "name": "PREB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076694", "map_id": "none", "name": "MIA2:PREB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BL12", "map_id": "E1BL12", "name": "PREB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LM15", "map_id": "A0A3Q1LM15", "name": "MIA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076586", "map_id": "none", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043590", "map_id": "none", "name": "GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1NDZ1", "map_id": "A0A3Q1NDZ1", "name": "GOSR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083081", "map_id": "ENSBTAT00000083081", "name": "GOSR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DB5", "map_id": "Q08DB5", "name": "STX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046561", "map_id": "ENSBTAT00000046561", "name": "STX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043594", "map_id": "F1MVW5", "name": "SEC23A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043592", "map_id": "F1MV07", "name": "SEC24D", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043596", "map_id": "none", "name": "SEC23A:SEC24C,D:GOSR2,STX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10076590", "map_id": "none", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043539", "map_id": "A0A3Q1MMA1", "name": "SEC22B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000066705", "map_id": "ENSBTAT00000066705", "name": "SEC22B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043651", "map_id": "A6QNT8", "name": "SEC24A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076588", "map_id": "none", "name": "SEC24A,B:SEC23A:SEC22B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MMA1", "map_id": "A0A3Q1MMA1", "name": "SEC22B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076706", "map_id": "none", "name": "CNIH2,3 bind GRIA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043622", "map_id": "G0T3G6", "name": "GRIA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000082647", "map_id": "ENSBTAT00000082647", "name": "GRIA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043618", "map_id": "none", "name": "CNIH2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LUP7", "map_id": "A0A3Q1LUP7", "name": "CNIH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076684", "map_id": "ENSBTAT00000076684", "name": "CNIH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N355", "map_id": "A0A3Q1N355", "name": "CNIH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081836", "map_id": "ENSBTAT00000081836", "name": "CNIH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043624", "map_id": "none", "name": "CNIH2,3:GRIA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G0T3G6", "map_id": "G0T3G6", "name": "GRIA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076708", "map_id": "none", "name": "CNIH1 binds TFGA and AREG precursors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043606", "map_id": "none", "name": "TFGA, AREG precursors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10043600", "map_id": "Q5BIN6", "name": "CNIH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000025975", "map_id": "ENSBTAT00000025975", "name": "CNIH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043608", "map_id": "none", "name": "CNIH1:TFGA,AREG precursors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q5BIN6", "map_id": "Q5BIN6", "name": "CNIH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076775", "map_id": "none", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10043626", "map_id": "none", "name": "COPII cargo:receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10043628", "map_id": "none", "name": "COPII cargo receptors:SAR1B:GTP:SEC23:SEC24", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10076584", "map_id": "none", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10076577", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "E1BKW5", "map_id": "E1BKW5", "name": "SEC23IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009785", "map_id": "ENSBTAT00000009785", "name": "SEC23IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N147", "map_id": "A0A3Q1N147", "name": "RAB1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070415", "map_id": "ENSBTAT00000070415", "name": "RAB1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T086", "map_id": "Q3T086", "name": "TRAPPC6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009288", "map_id": "ENSBTAT00000009288", "name": "TRAPPC6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MRB3", "map_id": "A0A3Q1MRB3", "name": "TRAPPC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079685", "map_id": "ENSBTAT00000079685", "name": "TRAPPC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QI1", "map_id": "Q17QI1", "name": "TRAPPC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065281", "map_id": "ENSBTAT00000065281", "name": "TRAPPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32L78", "map_id": "Q32L78", "name": "TRAPPC6B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019999", "map_id": "ENSBTAT00000019999", "name": "TRAPPC6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBL9", "map_id": "Q2TBL9", "name": "TRAPPC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010619", "map_id": "ENSBTAT00000010619", "name": "TRAPPC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4U3", "map_id": "A0A3Q1M4U3", "name": "TRAPPC10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087207", "map_id": "ENSBTAT00000087207", "name": "TRAPPC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSD6", "map_id": "F1MSD6", "name": "TRAPPC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005590", "map_id": "ENSBTAT00000005590", "name": "TRAPPC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0F2", "map_id": "Q3T0F2", "name": "TRAPPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014509", "map_id": "ENSBTAT00000014509", "name": "TRAPPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076581", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "reaction_10076635", "map_id": "none", "name": "PP6 dephosphorylates SEC24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10076618", "map_id": "none", "name": "p-SEC24", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043653", "map_id": "none", "name": "SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10076632", "map_id": "none", "name": "PP6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BN43", "map_id": "E1BN43", "name": "ANKRD28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034553", "map_id": "ENSBTAT00000034553", "name": "ANKRD28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIC7", "map_id": "Q2KIC7", "name": "PPP6C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010568", "map_id": "ENSBTAT00000010568", "name": "PPP6C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N214", "map_id": "G3N214", "name": "PPP6R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066016", "map_id": "ENSBTAT00000066016", "name": "PPP6R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076778", "map_id": "none", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043642", "map_id": "none", "name": "SAR1B:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076698", "map_id": "none", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10076575", "map_id": "none", "name": "TRAPPCII", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10076493", "map_id": "none", "name": "RAB1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10076537", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "reaction_10043649", "map_id": "none", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10083377", "map_id": "none", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10082020", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10083373", "map_id": "Q2T9Q1", "name": "TBC1D20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "ENSBTAT00000017725", "map_id": "ENSBTAT00000017725", "name": "TBC1D20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083375", "map_id": "none", "name": "RAB1:GTP:TBC1D20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "Q2T9Q1", "map_id": "Q2T9Q1", "name": "TBC1D20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076736", "map_id": "none", "name": "BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10076704", "map_id": "none", "name": "COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "P41541", "map_id": "P41541", "name": "USO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022642", "map_id": "ENSBTAT00000022642", "name": "USO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTM9", "map_id": "A0A3Q1LTM9", "name": "GOLGA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084718", "map_id": "ENSBTAT00000084718", "name": "GOLGA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M072", "map_id": "A0A3Q1M072", "name": "GORASP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084758", "map_id": "ENSBTAT00000084758", "name": "GORASP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076667", "map_id": "none", "name": "BET1:GOSR2:STX5:SCFD1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "A0A3Q1MJE3", "map_id": "A0A3Q1MJE3", "name": "BET1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082298", "map_id": "ENSBTAT00000082298", "name": "BET1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG76", "map_id": "E1BG76", "name": "SCFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046085", "map_id": "ENSBTAT00000046085", "name": "SCFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076596", "map_id": "none", "name": "GOLGA2:GORASP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10076677", "map_id": "none", "name": "cis-SNARE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10076734", "map_id": "none", "name": "COPII cargo:receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10076602", "map_id": "none", "name": "USO1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076610", "map_id": "none", "name": "RAB1:GTP binds USO1 and GORASP1:GOLGA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10076608", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10083380", "map_id": "none", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "reaction_10082026", "map_id": "none", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10082024", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10082045", "map_id": "none", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10082036", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10082042", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10082038", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "reaction_10053337", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_964831", "map_id": "none", "name": "(GlcNAc)2 (Man)8 glycans", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "CHEBI:60629", "map_id": "CHEBI:60629", "name": "CHEBI:60629", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60628", "map_id": "CHEBI:60628", "name": "CHEBI:60628", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60627", "map_id": "CHEBI:60627", "name": "CHEBI:60627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_964752", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_964740", "map_id": "CHEBI:59087", "name": "(GlcNAc)2 (Man)5 (Asn)1", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10053314", "map_id": "none", "name": "MAN1A1/A2/C1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BNG2", "map_id": "E1BNG2", "name": "MAN1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061143", "map_id": "ENSBTAT00000061143", "name": "MAN1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKX0", "map_id": "A0A3Q1MKX0", "name": "MAN1A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072527", "map_id": "ENSBTAT00000072527", "name": "MAN1A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7B0", "map_id": "E1B7B0", "name": "MAN1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061594", "map_id": "ENSBTAT00000061594", "name": "MAN1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053339", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_964828", "map_id": "CHEBI:60637", "name": "(GlcNAc)2 (Man)7bc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10053317", "map_id": "none", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_915149", "map_id": "CHEBI:59092", "name": "(GlcNAc)2 (Man)9", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10053324", "map_id": "none", "name": "Alternative endo-mannosidase I route", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_964754", "map_id": "CHEBI:59084", "name": "(Glc)3 (GlcNAc)2 (Man)9 (Asn)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_964744", "map_id": "CHEBI:59089", "name": "(GlcNAc)2 (Man)8 (Asn)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_964746", "map_id": "CHEBI:17925", "name": "Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10053321", "map_id": "F1ML11", "name": "MANEA", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000006614", "map_id": "ENSBTAT00000006614", "name": "MANEA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053331", "map_id": "none", "name": "Addition of GlcNAc to the glycan on the A arm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_964837", "map_id": "CHEBI:60625", "name": "(GlcNAc)3 (Man)5 (Asn)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10053328", "map_id": "Q5E9I4", "name": "MGAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "ENSBTAT00000066191", "map_id": "ENSBTAT00000066191", "name": "MGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084373", "map_id": "none", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8855720", "map_id": "CHEBI:37396", "name": "proteoglycan", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10084369", "map_id": "none", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q32KM0", "map_id": "Q32KM0", "name": "ASGR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016010", "map_id": "ENSBTAT00000016010", "name": "ASGR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ME82", "map_id": "F1ME82", "name": "ASGR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035098", "map_id": "ENSBTAT00000035098", "name": "ASGR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084371", "map_id": "none", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2:proteoglycan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056058", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056054", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_927893", "compartment_display": "endoplasmic reticulum quality control compartment", "complex": "true" }, { "id": "species_10056056", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089391", "map_id": "none", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10089384", "map_id": "none", "name": "Mitochondrial targeting peptides (from inner membrane proteins)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q02372", "map_id": "Q02372", "name": "NDUFB8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000100", "map_id": "ENSBTAT00000000100", "name": "NDUFB8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089388", "map_id": "F1MFA3", "name": "PITRM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000046212", "map_id": "ENSBTAT00000046212", "name": "PITRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056912", "map_id": "none", "name": "Movement of clathrin coated vesicles into early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane" }, { "id": "species_10056833", "map_id": "none", "name": "MR:soluble antigen", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "species_1236715", "map_id": "CHEBI:16670", "name": "Exogenous soluble antigen", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "E1BB51", "map_id": "E1BB51", "name": "CD207", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005993", "map_id": "ENSBTAT00000005993", "name": "CD207", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZP99", "map_id": "A0A3S5ZP99", "name": "FCGR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011333", "map_id": "ENSBTAT00000011333", "name": "FCGR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056803", "map_id": "none", "name": "MR:soluble antigen", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "reaction_10056835", "map_id": "none", "name": "Internalization of receptor bound antigen into clathrin coted vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane" }, { "id": "species_10056819", "map_id": "none", "name": "MR:soluble antigen", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056805", "map_id": "none", "name": "Exogenous soluble antigen targeted to more stable early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171043", "compartment_display": "early endosome lumen" }, { "id": "species_10056801", "map_id": "none", "name": "MR/other probable receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "reaction_10087823", "map_id": "none", "name": "CALR, TAP, TAPBP dissociate from SEC22B:STX4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10084863", "map_id": "none", "name": "CALR:SEC22B:STX4:TAP:TAPBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "species_10087813", "map_id": "none", "name": "SEC22B:STX4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "species_10087809", "map_id": "A5D7J6", "name": "CALR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "false" }, { "id": "species_10087821", "map_id": "Q2NL04", "name": "TAPBP", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "false" }, { "id": "species_10087819", "map_id": "none", "name": "TAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10084865", "map_id": "none", "name": "SEC22B, CALR, STX4, TAP and TAPBP bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10084853", "map_id": "A0A452DIB2", "name": "STX4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "false" }, { "id": "species_10084851", "map_id": "A5D7J6", "name": "CALR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "species_10084861", "map_id": "Q2NL04", "name": "TAPBP", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "species_10076669", "map_id": "A0A3Q1MMA1", "name": "SEC22B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "species_10084859", "map_id": "none", "name": "TAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10084867", "map_id": "none", "name": "Transport of SEC22B, TAP and PLC from ER to ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10055470", "map_id": "A5D7J6", "name": "CALR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10055468", "map_id": "Q2NL04", "name": "TAPBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10056982", "map_id": "none", "name": "Export of peptide loaded MHC class I complex to PM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_10056980", "map_id": "none", "name": "Ag peptide bound class I MHC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10056910", "map_id": "none", "name": "Trimming of peptides by IRAP in endocytic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1236722", "map_id": "CHEBI:25676", "name": "precursor peptide fragment (>16 aa)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_8943711", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_10056907", "map_id": "none", "name": "IRAP in complex with MHC class I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "A0A3Q1MAQ4", "map_id": "A0A3Q1MAQ4", "name": "LNPEP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080071", "map_id": "ENSBTAT00000080071", "name": "LNPEP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056914", "map_id": "none", "name": "Translocation of peptide bound MHC class I complex to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056901", "map_id": "none", "name": "Antigen peptide bound class I MHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "reaction_10056903", "map_id": "none", "name": "Loading of antigen peptide onto MHC class I molecule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171043", "compartment_display": "early endosome lumen" }, { "id": "species_10056899", "map_id": "none", "name": "Class I MHC:B2M", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "reaction_10057004", "map_id": "none", "name": "Alkalization of the phagosomal lumen by NOX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263698", "compartment_display": "phagolysosome" }, { "id": "species_1236709", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_263698", "compartment_display": "phagolysosome", "complex": "false" }, { "id": "species_2000347", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_263698", "compartment_display": "phagolysosome", "complex": "false" }, { "id": "species_2000345", "map_id": "CHEBI:18421", "name": "O2.-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_263698", "compartment_display": "phagolysosome", "complex": "false" }, { "id": "species_2000349", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_263698", "compartment_display": "phagolysosome", "complex": "false" }, { "id": "species_2000348", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_263698", "compartment_display": "phagolysosome", "complex": "false" }, { "id": "species_10057001", "map_id": "none", "name": "NOX2 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "O46521", "map_id": "O46521", "name": "CYBA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067849", "map_id": "ENSBTAT00000067849", "name": "CYBA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHY1", "map_id": "A0A452DHY1", "name": "phospho-NCF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004279", "map_id": "ENSBTAT00000004279", "name": "phospho-NCF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKI4", "map_id": "A0A3Q1MKI4", "name": "phospho-NCF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084691", "map_id": "ENSBTAT00000084691", "name": "phospho-NCF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTW8", "map_id": "A0A3Q1MTW8", "name": "phospho-NCF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076657", "map_id": "ENSBTAT00000076657", "name": "phospho-NCF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041962", "map_id": "none", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_198852", "map_id": "CHEBI:58539", "name": "DeHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_198827", "map_id": "CHEBI:58539", "name": "DeHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041959", "map_id": "A2VDL2", "name": "SLC2A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000042889", "map_id": "ENSBTAT00000042889", "name": "SLC2A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041955", "map_id": "none", "name": "GSTO dimers reduce DeHA to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_198816", "map_id": "CHEBI:38290", "name": "AscH-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111745", "map_id": "CHEBI:17858", "name": "GSSG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041952", "map_id": "none", "name": "GSTO dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BED9", "map_id": "E1BED9", "name": "GSTO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005211", "map_id": "ENSBTAT00000005211", "name": "GSTO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041975", "map_id": "none", "name": "SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_198836", "map_id": "CHEBI:38290", "name": "AscH-", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10041972", "map_id": "none", "name": "SLC23A1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BI45", "map_id": "E1BI45", "name": "SLC23A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010823", "map_id": "ENSBTAT00000010823", "name": "SLC23A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BP61", "map_id": "E1BP61", "name": "SLC23A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083275", "map_id": "ENSBTAT00000083275", "name": "SLC23A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083656", "map_id": "none", "name": "PTK6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083480", "map_id": "E1BNA8", "name": "phospho-PTK6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083654", "map_id": "E1BNA8", "name": "phospho-PTK6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10083672", "map_id": "none", "name": "PTK6 phosphorylates KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10083662", "map_id": "none", "name": "p-Y342-PTK6:KHDRBS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q29RQ2", "map_id": "Q29RQ2", "name": "KHDRBS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016581", "map_id": "ENSBTAT00000016581", "name": "KHDRBS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083669", "map_id": "Q29RQ2", "name": "phospho-KHDRBS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10083676", "map_id": "none", "name": "Phosphorylated KHDRBS1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10083674", "map_id": "Q29RQ2", "name": "phospho-KHDRBS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083664", "map_id": "none", "name": "PTK6 binds KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10083660", "map_id": "Q29RQ2", "name": "KHDRBS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10037748", "map_id": "none", "name": "Arachidonic acid is oxidised to PGG2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_140356", "map_id": "CHEBI:15843", "name": "ARA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_140357", "map_id": "CHEBI:27647", "name": "PGG2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10037745", "map_id": "none", "name": "PTGS1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A452DI94", "map_id": "A0A452DI94", "name": "PTGS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008833", "map_id": "ENSBTAT00000008833", "name": "PTGS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:26355", "map_id": "CHEBI:26355", "name": "CHEBI:26355", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037751", "map_id": "none", "name": "PGG2 is reduced to PGH2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_76342", "map_id": "CHEBI:10545", "name": "e-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_30138", "map_id": "CHEBI:15554", "name": "PGH2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063448", "map_id": "none", "name": "Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046066", "map_id": "CHEBI:15531", "name": "Malonyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046060", "map_id": "CHEBI:63544", "name": "DTA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046048", "map_id": "CHEBI:63548", "name": "TTA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_162743", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_159751", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10051239", "map_id": "A4FUF2", "name": "ELOVL2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000074314", "map_id": "ENSBTAT00000074314", "name": "ELOVL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063450", "map_id": "none", "name": "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_194697", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046063", "map_id": "CHEBI:15530", "name": "LA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_194653", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046042", "map_id": "CHEBI:15508", "name": "GLA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10063417", "map_id": "A4FV48", "name": "FADS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000020610", "map_id": "ENSBTAT00000020610", "name": "FADS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063452", "map_id": "none", "name": "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046050", "map_id": "CHEBI:63546", "name": "TPA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063454", "map_id": "none", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211579", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046044", "map_id": "CHEBI:17351", "name": "LINA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_2046064", "map_id": "CHEBI:16027", "name": "adenosine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046049", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10063422", "map_id": "none", "name": "ACSL1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LWT4", "map_id": "A0A3Q1LWT4", "name": "ACSL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078831", "map_id": "ENSBTAT00000078831", "name": "ACSL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063442", "map_id": "none", "name": "Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046045", "map_id": "CHEBI:27979", "name": "DGL-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046053", "map_id": "CHEBI:15514", "name": "AA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10063434", "map_id": "A0A3Q1MF38", "name": "FADS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000082100", "map_id": "ENSBTAT00000082100", "name": "FADS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063413", "map_id": "none", "name": "Elongation of arachidonyl-CoA to docosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10063410", "map_id": "none", "name": "ELOVL5/ELOVL2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2KJD9", "map_id": "Q2KJD9", "name": "ELOVL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004358", "map_id": "ENSBTAT00000004358", "name": "ELOVL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FUF2", "map_id": "A4FUF2", "name": "ELOVL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063444", "map_id": "none", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5228339", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_2046055", "map_id": "CHEBI:63546", "name": "TPA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_211606", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10046702", "map_id": "Q2KJ57", "name": "ABCD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "ENSBTAT00000027382", "map_id": "ENSBTAT00000027382", "name": "ABCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063446", "map_id": "none", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10051249", "map_id": "none", "name": "ELOVL1,2,3,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BBR7", "map_id": "E1BBR7", "name": "ELOVL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020842", "map_id": "ENSBTAT00000020842", "name": "ELOVL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063437", "map_id": "none", "name": "Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046051", "map_id": "CHEBI:63542", "name": "ETA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046059", "map_id": "CHEBI:63539", "name": "EPA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063420", "map_id": "none", "name": "Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2046062", "map_id": "CHEBI:51985", "name": "ALA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046052", "map_id": "CHEBI:63545", "name": "SDA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063425", "map_id": "none", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2046056", "map_id": "CHEBI:27432", "name": "ALA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10063456", "map_id": "none", "name": "Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2046057", "map_id": "CHEBI:63541", "name": "DPA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063440", "map_id": "none", "name": "Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046065", "map_id": "CHEBI:63543", "name": "TPA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10063570", "map_id": "none", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_141343", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_2066765", "map_id": "CHEBI:65132", "name": "DHA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193514", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_2066763", "map_id": "CHEBI:28125", "name": "DHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10041305", "map_id": "A0A3Q1N6L4", "name": "ACOT8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000074004", "map_id": "ENSBTAT00000074004", "name": "ACOT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063573", "map_id": "none", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_2066762", "map_id": "CHEBI:65131", "name": "1-3-oxo-THA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_353123", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10047050", "map_id": "Q3ZC41", "name": "ACAA1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000024335", "map_id": "ENSBTAT00000024335", "name": "ACAA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063428", "map_id": "none", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2046054", "map_id": "CHEBI:63540", "name": "THA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2046047", "map_id": "CHEBI:63540", "name": "THA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10063430", "map_id": "none", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10033912", "map_id": "none", "name": "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70843", "map_id": "CHEBI:15539", "name": "PROP-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_71019", "map_id": "CHEBI:15466", "name": "MEMA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033909", "map_id": "none", "name": "6x(Btn-PCCA:PCCB)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1N969", "map_id": "A0A3Q1N969", "name": "PCCA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086761", "map_id": "ENSBTAT00000086761", "name": "PCCA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIR0", "map_id": "A0A452DIR0", "name": "PCCB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020252", "map_id": "ENSBTAT00000020252", "name": "PCCB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033896", "map_id": "none", "name": "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_71009", "map_id": "CHEBI:15465", "name": "L-MM-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033893", "map_id": "A0A452DJE5", "name": "MCEE", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000049741", "map_id": "ENSBTAT00000049741", "name": "MCEE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033889", "map_id": "none", "name": "MUT isomerises L-MM-CoA to SUCC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70958", "map_id": "CHEBI:57292", "name": "SUCC-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033884", "map_id": "none", "name": "2xMMAA:2xMUT:AdoCbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_3159297", "map_id": "CHEBI:18408", "name": "AdoCbl", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q0III1", "map_id": "Q0III1", "name": "MMUT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076678", "map_id": "ENSBTAT00000076678", "name": "MMUT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQI8", "map_id": "A6QQI8", "name": "MMAA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029806", "map_id": "ENSBTAT00000029806", "name": "MMAA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075631", "map_id": "none", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5690540", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33184", "map_id": "CHEBI:33184", "name": "CHEBI:33184", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:61907", "map_id": "CHEBI:61907", "name": "CHEBI:61907", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5690519", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_30495", "map_id": "CHEBI:15904", "name": "LCFA", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:59554", "map_id": "CHEBI:59554", "name": "CHEBI:59554", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075628", "map_id": "none", "name": "ACOT2,9, THEM4,5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A6QQA9", "map_id": "A6QQA9", "name": "ACOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074250", "map_id": "ENSBTAT00000074250", "name": "ACOT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N234", "map_id": "F1N234", "name": "ACOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAC0", "map_id": "E1BAC0", "name": "THEM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000922", "map_id": "ENSBTAT00000000922", "name": "THEM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036029", "map_id": "none", "name": "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77330", "map_id": "CHEBI:28632", "name": "(S)-Hydroxyoctanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77328", "map_id": "CHEBI:28264", "name": "3-Oxooctanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10036009", "map_id": "none", "name": "HADH dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LS03", "map_id": "A0A3Q1LS03", "name": "HADH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054475", "map_id": "ENSBTAT00000054475", "name": "HADH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036038", "map_id": "none", "name": "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77337", "map_id": "CHEBI:15533", "name": "Octanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77332", "map_id": "CHEBI:27537", "name": "trans-Oct-2-enoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10036035", "map_id": "none", "name": "ACADM tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q3SZB4", "map_id": "Q3SZB4", "name": "ACADM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033470", "map_id": "ENSBTAT00000033470", "name": "ACADM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036027", "map_id": "none", "name": "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77322", "map_id": "CHEBI:28276", "name": "(S)-Hydroxyhexanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77320", "map_id": "CHEBI:27648", "name": "3-Oxohexanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036040", "map_id": "none", "name": "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77341", "map_id": "CHEBI:28325", "name": "(S)-Hydroxydecanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77339", "map_id": "CHEBI:28528", "name": "3-Oxodecanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036042", "map_id": "none", "name": "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77308", "map_id": "CHEBI:28493", "name": "DEC-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77343", "map_id": "CHEBI:10723", "name": "tdec2-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036012", "map_id": "none", "name": "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77252", "map_id": "CHEBI:27668", "name": "(S)-3-Hydroxydodecanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77253", "map_id": "CHEBI:27868", "name": "3-Oxododecanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036021", "map_id": "none", "name": "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77261", "map_id": "CHEBI:15521", "name": "LAU-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77255", "map_id": "CHEBI:15471", "name": "2-trans-Dodecenoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10036018", "map_id": "none", "name": "ACADL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q08D92", "map_id": "Q08D92", "name": "ACADL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013988", "map_id": "ENSBTAT00000013988", "name": "ACADL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036025", "map_id": "none", "name": "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77251", "map_id": "CHEBI:15453", "name": "3HB-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_73871", "map_id": "CHEBI:15345", "name": "ACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036023", "map_id": "none", "name": "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77272", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77273", "map_id": "CHEBI:27721", "name": "trans-Tetradec-2-enoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10086403", "map_id": "none", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_977314", "map_id": "CHEBI:15531", "name": "Malonyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10086393", "map_id": "G3X6L0", "name": "phospho-NDUFAB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000008382", "map_id": "ENSBTAT00000008382", "name": "phospho-NDUFAB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086396", "map_id": "G3X6L0", "name": "phospho-NDUFAB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10086400", "map_id": "E1BPG0", "name": "MCAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000003130", "map_id": "ENSBTAT00000003130", "name": "MCAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036664", "map_id": "none", "name": "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_109994", "map_id": "CHEBI:29126", "name": "3-trans-decenoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10036215", "map_id": "none", "name": "DCI dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F1MTT7", "map_id": "F1MTT7", "name": "ECI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013144", "map_id": "ENSBTAT00000013144", "name": "ECI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036218", "map_id": "none", "name": "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77358", "map_id": "CHEBI:28002", "name": "cis,cis-3,6-Dodecadienoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77360", "map_id": "CHEBI:28387", "name": "trans,cis-Lauro-2,6-dienoyl-CoA ", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10036220", "map_id": "none", "name": "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_109986", "map_id": "CHEBI:29140", "name": "4-cis-decenoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_109990", "map_id": "CHEBI:29119", "name": "2-trans-4-cis-decadienoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10075607", "map_id": "none", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5690044", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5690064", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075600", "map_id": "none", "name": "Cytosolic ACOTs, THEM4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6QGE6", "map_id": "F6QGE6", "name": "ACOT13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021731", "map_id": "ENSBTAT00000021731", "name": "ACOT13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MI69", "map_id": "A0A3Q1MI69", "name": "ACOT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075163", "map_id": "ENSBTAT00000075163", "name": "ACOT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNW7", "map_id": "E1BNW7", "name": "ACOT12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014753", "map_id": "ENSBTAT00000014753", "name": "ACOT12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075605", "map_id": "P02720", "name": "PCTP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024898", "map_id": "ENSBTAT00000024898", "name": "PCTP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076806", "map_id": "none", "name": "ACAD10 dehydrogenates S-2MPDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5695946", "map_id": "CHEBI:85944", "name": "S-2MPDA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5695949", "map_id": "CHEBI:85945", "name": "S-2MDPDA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076803", "map_id": "A0A3Q1M516", "name": "LOC513508", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000080862", "map_id": "ENSBTAT00000080862", "name": "LOC513508", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042860", "map_id": "none", "name": "CPT1A,B transfers PALM to CAR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_549207", "map_id": "CHEBI:17126", "name": "CAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_200993", "map_id": "CHEBI:15525", "name": "PALM-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_201034", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10042857", "map_id": "none", "name": "CPT1A,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "A0A3Q1LMV3", "map_id": "A0A3Q1LMV3", "name": "CPT1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069870", "map_id": "ENSBTAT00000069870", "name": "CPT1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DK1", "map_id": "Q58DK1", "name": "CPT1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021357", "map_id": "ENSBTAT00000021357", "name": "CPT1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29508", "map_id": "CHEBI:15531", "name": "Mal-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10042897", "map_id": "none", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_201023", "map_id": "CHEBI:17126", "name": "CAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_201050", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10042894", "map_id": "Q3SZA4", "name": "SLC25A20", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000000217", "map_id": "ENSBTAT00000000217", "name": "SLC25A20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085185", "map_id": "none", "name": "MID1IP1 binds THRSP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085181", "map_id": "A0A3S5ZPK2", "name": "THRSP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000015490", "map_id": "ENSBTAT00000015490", "name": "THRSP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085177", "map_id": "Q08E46", "name": "MID1IP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000015231", "map_id": "ENSBTAT00000015231", "name": "MID1IP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085183", "map_id": "none", "name": "MID1IP1:THRSP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08E46", "map_id": "Q08E46", "name": "MID1IP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPK2", "map_id": "A0A3S5ZPK2", "name": "THRSP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077001", "map_id": "none", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_192172", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5696426", "map_id": "CHEBI:75627", "name": "ARACOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5696412", "map_id": "CHEBI:10036", "name": "arachidyl ester", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10076998", "map_id": "F1MVD1", "name": "AWAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000025081", "map_id": "ENSBTAT00000025081", "name": "AWAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044657", "map_id": "none", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266013", "map_id": "CHEBI:16978", "name": "LTC4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_266074", "map_id": "CHEBI:28666", "name": "LTD4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10044654", "map_id": "none", "name": "GGT1, 5 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MYJ3", "map_id": "F1MYJ3", "name": "GGT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023658", "map_id": "ENSBTAT00000023658", "name": "GGT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2D8", "map_id": "G3N2D8", "name": "GGT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063999", "map_id": "ENSBTAT00000063999", "name": "GGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064482", "map_id": "none", "name": "20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142740", "map_id": "CHEBI:63979", "name": "20cho-LTB4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064581", "map_id": "none", "name": "LTA4 is converted to EXA4 by ALOX15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265281", "map_id": "CHEBI:15651", "name": "LTA4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142772", "map_id": "CHEBI:63983", "name": "EXA4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064560", "map_id": "none", "name": "ALOX15:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27479", "map_id": "P27479", "name": "ALOX15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015911", "map_id": "ENSBTAT00000015911", "name": "ALOX15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_71067", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064503", "map_id": "none", "name": "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2161582", "map_id": "CHEBI:27562", "name": "20cooh-LTB4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064578", "map_id": "none", "name": "Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29768", "map_id": "CHEBI:15843", "name": "AA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142718", "map_id": "CHEBI:15628", "name": "15S-HpETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064575", "map_id": "none", "name": "ALOX15/15B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MXW0", "map_id": "F1MXW0", "name": "ALOX15B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011570", "map_id": "ENSBTAT00000011570", "name": "ALOX15B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064546", "map_id": "none", "name": "Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142738", "map_id": "CHEBI:63989", "name": "15R-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064543", "map_id": "none", "name": "Ac-PTGS2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MNI5", "map_id": "F1MNI5", "name": "PTGS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018774", "map_id": "ENSBTAT00000018774", "name": "PTGS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064554", "map_id": "none", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142790", "map_id": "CHEBI:34145", "name": "12R-HpETE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142716", "map_id": "CHEBI:34144", "name": "12R-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064551", "map_id": "Q9N2J2", "name": "GPX4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070793", "map_id": "ENSBTAT00000070793", "name": "GPX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064565", "map_id": "none", "name": "Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142811", "map_id": "CHEBI:15626", "name": "12S-HpETE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064562", "map_id": "none", "name": "ALOX12/15", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MFA8", "map_id": "F1MFA8", "name": "ALOX12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029240", "map_id": "ENSBTAT00000029240", "name": "ALOX12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064567", "map_id": "none", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142678", "map_id": "CHEBI:34146", "name": "12S-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064534", "map_id": "none", "name": "Arachidonic acid is converted to 12-oxoETE by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142745", "map_id": "CHEBI:34151", "name": "12-oxoETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064488", "map_id": "none", "name": "ALOX12:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076382", "map_id": "none", "name": "FAAH hydrolyses AEA to AA and ETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5693754", "map_id": "CHEBI:2700", "name": "AEA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_1498751", "map_id": "CHEBI:16000", "name": "ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076379", "map_id": "A0A3Q1MIZ4", "name": "FAAH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000071864", "map_id": "ENSBTAT00000071864", "name": "FAAH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064506", "map_id": "none", "name": "Arachidonic acid is converted to HXA3/B3 by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2162031", "map_id": "none", "name": "HXA3/B3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:36190", "map_id": "CHEBI:36190", "name": "CHEBI:36190", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34784", "map_id": "CHEBI:34784", "name": "CHEBI:34784", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086336", "map_id": "none", "name": "PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8932801", "map_id": "CHEBI:132873", "name": "5-HETEL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8932804", "map_id": "CHEBI:60943", "name": "5-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10086333", "map_id": "none", "name": "PON1,2,3:2xCa2+ dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q1JQD3", "map_id": "Q1JQD3", "name": "PON3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049076", "map_id": "ENSBTAT00000049076", "name": "PON3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIW1", "map_id": "Q2KIW1", "name": "PON1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020790", "map_id": "ENSBTAT00000020790", "name": "PON1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064521", "map_id": "none", "name": "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142739", "map_id": "CHEBI:34450", "name": "5,6-EET", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10064518", "map_id": "none", "name": "CYP(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MM10", "map_id": "F1MM10", "name": "CYP1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061300", "map_id": "ENSBTAT00000061300", "name": "CYP1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHN9", "map_id": "F1MHN9", "name": "CYP1A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000094", "map_id": "ENSBTAT00000000094", "name": "CYP1A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MNG1", "map_id": "F1MNG1", "name": "CYP1B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075887", "map_id": "ENSBTAT00000075887", "name": "CYP1B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3N3", "map_id": "F1N3N3", "name": "LOC530929", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000051914", "map_id": "ENSBTAT00000051914", "name": "LOC530929", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QW09", "map_id": "M0QW09", "name": "LOC107132327", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018202", "map_id": "ENSBTAT00000018202", "name": "LOC107132327", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064526", "map_id": "none", "name": "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2161753", "map_id": "none", "name": "8,9/11,12/14,15-EET", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:34130", "map_id": "CHEBI:34130", "name": "CHEBI:34130", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34490", "map_id": "CHEBI:34490", "name": "CHEBI:34490", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:34157", "map_id": "CHEBI:34157", "name": "CHEBI:34157", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064523", "map_id": "none", "name": "CYP(5)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3S5ZP79", "map_id": "A0A3S5ZP79", "name": "CYP2C87", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027159", "map_id": "ENSBTAT00000027159", "name": "CYP2C87", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEU8", "map_id": "F1MEU8", "name": "LOC540627", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008918", "map_id": "ENSBTAT00000008918", "name": "LOC540627", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065210", "map_id": "none", "name": "PGG2 is reduced to PGH2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10065205", "map_id": "none", "name": "PTGS2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_549282", "map_id": "CHEBI:16797", "name": "MNA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10065208", "map_id": "none", "name": "PTGS2 dimer:PTGS2 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064442", "map_id": "none", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265283", "map_id": "CHEBI:15554", "name": "PGH2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_879535", "map_id": "CHEBI:15553", "name": "PGF2a", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10041165", "map_id": "none", "name": "Homologues of AKR1C1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BP71", "map_id": "E1BP71", "name": "LOC782884", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039350", "map_id": "ENSBTAT00000039350", "name": "LOC782884", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QW21", "map_id": "M0QW21", "name": "AKR1C3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028488", "map_id": "ENSBTAT00000028488", "name": "AKR1C3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG58", "map_id": "E1BG58", "name": "LOC538060", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038997", "map_id": "ENSBTAT00000038997", "name": "LOC538060", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QW25", "map_id": "M0QW25", "name": "LOC527068", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030566", "map_id": "ENSBTAT00000030566", "name": "LOC527068", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QW04", "map_id": "M0QW04", "name": "LOC538060", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QW14", "map_id": "M0QW14", "name": "LOC782061", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023326", "map_id": "ENSBTAT00000023326", "name": "LOC782061", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MT58", "map_id": "F1MT58", "name": "LOC785762", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055749", "map_id": "ENSBTAT00000055749", "name": "LOC785762", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBG2", "map_id": "Q3ZBG2", "name": "AKR1C4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023297", "map_id": "ENSBTAT00000023297", "name": "AKR1C4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X704", "map_id": "G3X704", "name": "LOC782061", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MK69", "map_id": "F1MK69", "name": "20ALPHA-HSD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056823", "map_id": "ENSBTAT00000056823", "name": "20ALPHA-HSD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52897", "map_id": "P52897", "name": "AKR1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024086", "map_id": "ENSBTAT00000024086", "name": "AKR1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MNC0", "map_id": "F1MNC0", "name": "LOC506594", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039362", "map_id": "ENSBTAT00000039362", "name": "LOC506594", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P52898", "map_id": "P52898", "name": "AKR1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064474", "map_id": "none", "name": "PGH2 is isomerised to PGE2 by PTGES", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_265287", "map_id": "CHEBI:15551", "name": "PGE2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10064471", "map_id": "none", "name": "PTGES trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q95L14", "map_id": "Q95L14", "name": "PTGES", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025912", "map_id": "ENSBTAT00000025912", "name": "PTGES", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065213", "map_id": "none", "name": "PTGS2 dimer binds PTGS2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9716714", "map_id": "none", "name": "PTGS2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064445", "map_id": "none", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_879629", "map_id": "CHEBI:15555", "name": "PGD2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142710", "map_id": "CHEBI:27595", "name": "11epi-PGF2a", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064479", "map_id": "none", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10064476", "map_id": "none", "name": "HPGDS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MGZ9", "map_id": "F1MGZ9", "name": "HPGDS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022700", "map_id": "ENSBTAT00000022700", "name": "HPGDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064465", "map_id": "none", "name": "PGE2 is converted to PGF2a by CBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10064462", "map_id": "none", "name": "Homologues of CBR1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NG39", "map_id": "A0A3Q1NG39", "name": "LOC112441473", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084736", "map_id": "ENSBTAT00000084736", "name": "LOC112441473", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0T9", "map_id": "Q3T0T9", "name": "MGC127133", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043292", "map_id": "ENSBTAT00000043292", "name": "MGC127133", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044599", "map_id": "none", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044596", "map_id": "none", "name": "PTGES2(88-377), PTGES3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LFK5", "map_id": "A0A3Q1LFK5", "name": "PTGES2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071669", "map_id": "ENSBTAT00000071669", "name": "PTGES2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIU3", "map_id": "A0A452DIU3", "name": "PTGES3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023908", "map_id": "ENSBTAT00000023908", "name": "PTGES3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065225", "map_id": "none", "name": "Aspirin acetylates PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2314693", "map_id": "CHEBI:13719", "name": "acetylsalicylate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2314690", "map_id": "CHEBI:30762", "name": "salicylate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065216", "map_id": "none", "name": "Arachidonic acid is oxidised to PGG2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10064452", "map_id": "none", "name": "PGH2 is isomerised to PGD2 by PTGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2161634", "map_id": "CHEBI:15555", "name": "PGD2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10064449", "map_id": "O02853", "name": "PTGDS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000020065", "map_id": "ENSBTAT00000020065", "name": "PTGDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065223", "map_id": "none", "name": "Aspirin acetylates PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065221", "map_id": "none", "name": "Ac-PTGS1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064511", "map_id": "none", "name": "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2161639", "map_id": "none", "name": "16/17/18-HETE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:63995", "map_id": "CHEBI:63995", "name": "CHEBI:63995", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63994", "map_id": "CHEBI:63994", "name": "CHEBI:63994", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63579", "map_id": "CHEBI:63579", "name": "CHEBI:63579", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064508", "map_id": "none", "name": "CYP(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064531", "map_id": "none", "name": "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142780", "map_id": "CHEBI:34306", "name": "20-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10064528", "map_id": "none", "name": "CYP(3)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1N3I8", "map_id": "F1N3I8", "name": "LOC784417", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021785", "map_id": "ENSBTAT00000021785", "name": "LOC784417", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFI9", "map_id": "F1MFI9", "name": "CYP2U1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017246", "map_id": "ENSBTAT00000017246", "name": "CYP2U1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064516", "map_id": "none", "name": "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2142836", "map_id": "CHEBI:63998", "name": "19-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10064513", "map_id": "none", "name": "CYP(2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10047033", "map_id": "none", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_113535", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389893", "map_id": "CHEBI:64039", "name": "(2S) Pristanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_113575", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389894", "map_id": "CHEBI:63803", "name": "trans-2,3-dehydropristanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10047030", "map_id": "none", "name": "ACOX2:FAD, ACOXL:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "A0A3Q1LWZ7", "map_id": "A0A3Q1LWZ7", "name": "ACOXL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082299", "map_id": "ENSBTAT00000082299", "name": "ACOXL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRF5", "map_id": "F1MRF5", "name": "ACOX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005472", "map_id": "ENSBTAT00000005472", "name": "ACOX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047056", "map_id": "none", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390305", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10047042", "map_id": "none", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_10047039", "map_id": "none", "name": "ACOX3:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "A4IFA4", "map_id": "A4IFA4", "name": "ACOX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044120", "map_id": "ENSBTAT00000044120", "name": "ACOX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047044", "map_id": "none", "name": "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389569", "map_id": "CHEBI:51341", "name": "(2R) Pristanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10041183", "map_id": "F1MCN8", "name": "AMACR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000029075", "map_id": "ENSBTAT00000029075", "name": "AMACR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077835", "map_id": "none", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6787810", "map_id": "CHEBI:65101", "name": "2OH-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6787814", "map_id": "CHEBI:86988", "name": "2oxo-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10077832", "map_id": "none", "name": "HAO2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "Q3ZBW2", "map_id": "Q3ZBW2", "name": "HAO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000134", "map_id": "ENSBTAT00000000134", "name": "HAO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077784", "map_id": "none", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193465", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6786723", "map_id": "CHEBI:83727", "name": "LCtE-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_113602", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6786715", "map_id": "CHEBI:27700", "name": "t3enoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389556", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10077781", "map_id": "A0A3Q1LRU3", "name": "DECR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "ENSBTAT00000072961", "map_id": "ENSBTAT00000072961", "name": "DECR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075576", "map_id": "none", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_5690520", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "species_5690539", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "species_10075573", "map_id": "none", "name": "ACOT4,6,8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "A0A3Q1N6L4", "map_id": "A0A3Q1N6L4", "name": "ACOT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPS3", "map_id": "A0A3S5ZPS3", "name": "ACOT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003683", "map_id": "ENSBTAT00000003683", "name": "ACOT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBG0", "map_id": "E1BBG0", "name": "LOC512541", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013568", "map_id": "ENSBTAT00000013568", "name": "LOC512541", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047053", "map_id": "none", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_390241", "map_id": "CHEBI:52977", "name": "3-ketohexacosanoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_390246", "map_id": "CHEBI:52974", "name": "tetracosanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10082880", "map_id": "none", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6809801", "map_id": "CHEBI:85939", "name": "3Z-octenoyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6809800", "map_id": "CHEBI:27537", "name": "2E-octenoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10082877", "map_id": "none", "name": "ECI2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "A0A3Q1LP28", "map_id": "A0A3Q1LP28", "name": "ECI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083505", "map_id": "ENSBTAT00000083505", "name": "ECI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054592", "map_id": "none", "name": "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_977323", "map_id": "CHEBI:15531", "name": "Malonyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389536", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10054589", "map_id": "A5PJC5", "name": "MLYCD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000005562", "map_id": "ENSBTAT00000005562", "name": "MLYCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047058", "map_id": "none", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_390394", "map_id": "CHEBI:52966", "name": "C26:0 CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_390260", "map_id": "CHEBI:52966", "name": "C26:0 CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10046704", "map_id": "none", "name": "ABCD1 homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "Q2KJ57", "map_id": "Q2KJ57", "name": "ABCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082889", "map_id": "none", "name": "PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_6809811", "map_id": "none", "name": "2E-phytenoyl-CoA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389615", "map_id": "CHEBI:15538", "name": "Phytanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10082886", "map_id": "none", "name": "PECR tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "G3X6L7", "map_id": "G3X6L7", "name": "PECR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008962", "map_id": "ENSBTAT00000008962", "name": "PECR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047001", "map_id": "none", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389537", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389594", "map_id": "CHEBI:15475", "name": "3S2HPhy-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389583", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10046998", "map_id": "none", "name": "PHYH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "O18778", "map_id": "O18778", "name": "PHYH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010126", "map_id": "ENSBTAT00000010126", "name": "PHYH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046984", "map_id": "none", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389636", "map_id": "CHEBI:49189", "name": "Pristanal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192307", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6811612", "map_id": "CHEBI:77268", "name": "pristanate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192305", "map_id": "CHEBI:57945", "name": "NADH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10046981", "map_id": "none", "name": "ALDH3A2-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "A0A3Q1LJ52", "map_id": "A0A3Q1LJ52", "name": "ALDH3A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070862", "map_id": "ENSBTAT00000070862", "name": "ALDH3A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046989", "map_id": "none", "name": "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389596", "map_id": "CHEBI:16285", "name": "Phytanate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389573", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389593", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389620", "map_id": "CHEBI:16027", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10046986", "map_id": "A0A3Q1M4C7", "name": "SLC27A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "ENSBTAT00000078122", "map_id": "ENSBTAT00000078122", "name": "SLC27A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046992", "map_id": "none", "name": "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "reaction_10083389", "map_id": "none", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_428139", "map_id": "CHEBI:15541", "name": "ST-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4085415", "map_id": "CHEBI:16518", "name": "Fe(2+)Cb5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4085425", "map_id": "CHEBI:18097", "name": "Fe(3+)Cb5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5690558", "map_id": "CHEBI:15534", "name": "OLE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083386", "map_id": "none", "name": "SCD5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2KIA4", "map_id": "Q2KIA4", "name": "SCD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025820", "map_id": "ENSBTAT00000025820", "name": "SCD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051261", "map_id": "none", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548812", "map_id": "CHEBI:50571", "name": "3OOD-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051258", "map_id": "none", "name": "ELOVL3,6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A6QNQ7", "map_id": "A6QNQ7", "name": "ELOVL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067475", "map_id": "ENSBTAT00000067475", "name": "ELOVL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042961", "map_id": "none", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3632881", "map_id": "CHEBI:15756", "name": "PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10042958", "map_id": "none", "name": "ACSL1,3,5,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q1LZF6", "map_id": "Q1LZF6", "name": "ACSL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064114", "map_id": "ENSBTAT00000064114", "name": "ACSL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPX2", "map_id": "A0A3Q1LPX2", "name": "ACSL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080693", "map_id": "ENSBTAT00000080693", "name": "ACSL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEX9", "map_id": "F1MEX9", "name": "ACSL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022939", "map_id": "ENSBTAT00000022939", "name": "ACSL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074353", "map_id": "none", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5676631", "map_id": "CHEBI:15456", "name": "VLC3HA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5676634", "map_id": "CHEBI:50998", "name": "2,3-TE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10074350", "map_id": "none", "name": "PTPLs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MXJ1", "map_id": "F1MXJ1", "name": "HACD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046976", "map_id": "ENSBTAT00000046976", "name": "HACD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051252", "map_id": "none", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548816", "map_id": "CHEBI:63821", "name": "3ODCT-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044985", "map_id": "none", "name": "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352186", "map_id": "none", "name": "ligands of SLC38A3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_352036", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_29612", "map_id": "CHEBI:32513", "name": "L-His", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29642", "map_id": "CHEBI:58048", "name": "L-Asn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_352169", "map_id": "none", "name": "ligands of SLC38A3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044982", "map_id": "F1MXZ5", "name": "SLC38A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000011214", "map_id": "ENSBTAT00000011214", "name": "SLC38A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044955", "map_id": "none", "name": "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352101", "map_id": "none", "name": "ligands of SLC43A1 and SLC43A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:58045", "map_id": "CHEBI:58045", "name": "CHEBI:58045", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:57427", "map_id": "CHEBI:57427", "name": "CHEBI:57427", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_174390", "map_id": "CHEBI:57844", "name": "L-Met", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_351993", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_29702", "map_id": "CHEBI:57762", "name": "L-Val", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_352114", "map_id": "none", "name": "ligands of SLC43A1 and SLC43A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044952", "map_id": "A0A3Q1MUY6", "name": "SLC43A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000072259", "map_id": "ENSBTAT00000072259", "name": "SLC43A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045501", "map_id": "none", "name": "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375765", "map_id": "none", "name": "L-Arg, L-Lys, L-Orn", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32551", "map_id": "CHEBI:32551", "name": "CHEBI:32551", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113530", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_375781", "map_id": "none", "name": "L-Arg, L-Lys, L-Orn", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10045498", "map_id": "F1N5P6", "name": "SLC7A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019060", "map_id": "ENSBTAT00000019060", "name": "SLC7A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044978", "map_id": "none", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352161", "map_id": "none", "name": "ligands of SLC16A10", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_352006", "map_id": "CHEBI:57912", "name": "L-Trp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352030", "map_id": "CHEBI:58315", "name": "L-Tyr", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352139", "map_id": "none", "name": "ligands of SLC16A10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044975", "map_id": "F1MEU4", "name": "SLC16A10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000012176", "map_id": "ENSBTAT00000012176", "name": "SLC16A10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044948", "map_id": "none", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352051", "map_id": "none", "name": "ligands of SLC6A15", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_379717", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_351990", "map_id": "CHEBI:57926", "name": "L-Thr", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111707", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_379732", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "CHEBI:18240", "map_id": "CHEBI:18240", "name": "CHEBI:18240", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_352048", "map_id": "none", "name": "ligands of SLC6A15", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044945", "map_id": "Q9XS59", "name": "SLC6A15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000076418", "map_id": "ENSBTAT00000076418", "name": "SLC6A15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045494", "map_id": "none", "name": "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045491", "map_id": "F1MUG8", "name": "SLC7A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000009736", "map_id": "ENSBTAT00000009736", "name": "SLC7A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088905", "map_id": "none", "name": "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8959777", "map_id": "none", "name": "SLC25A29 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28229", "map_id": "CHEBI:28229", "name": "CHEBI:28229", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113586", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "CHEBI:27747", "map_id": "CHEBI:27747", "name": "CHEBI:27747", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8959775", "map_id": "none", "name": "SLC25A29 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10088902", "map_id": "Q08DK7", "name": "SLC25A29", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000018163", "map_id": "ENSBTAT00000018163", "name": "SLC25A29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085384", "map_id": "none", "name": "SLC36A4 transports extracellular L-Pro to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352033", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_113538", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10085378", "map_id": "G3X6P9", "name": "SLC36A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000011246", "map_id": "ENSBTAT00000011246", "name": "SLC36A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045480", "map_id": "none", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375458", "map_id": "none", "name": "neutral amino acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_29424", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_375481", "map_id": "none", "name": "neutral amino acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10045477", "map_id": "G5E6L1", "name": "SLC6A19", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064818", "map_id": "ENSBTAT00000064818", "name": "SLC6A19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044971", "map_id": "none", "name": "SLC38A4 (ATA3)-mediated uptake of arginine and lysine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352128", "map_id": "none", "name": "ligands of SLC38A4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_352135", "map_id": "none", "name": "ligands of SLC38A4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044968", "map_id": "F1MM24", "name": "SLC38A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000070473", "map_id": "ENSBTAT00000070473", "name": "SLC38A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044941", "map_id": "none", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_188972", "map_id": "CHEBI:17996", "name": "Cl-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352007", "map_id": "none", "name": "ligands of SLC6A12 (BGT-1)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_73590", "map_id": "CHEBI:16958", "name": "b-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428571", "map_id": "CHEBI:59888", "name": "GABA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_352015", "map_id": "CHEBI:17750", "name": "BET", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:48950", "map_id": "CHEBI:48950", "name": "CHEBI:48950", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_351982", "map_id": "none", "name": "ligands of SLC6A12 (BGT-1)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044938", "map_id": "A0A3Q1LJ84", "name": "SLC6A12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000067153", "map_id": "ENSBTAT00000067153", "name": "SLC6A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045487", "map_id": "none", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375468", "map_id": "none", "name": "SLC6A14 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_375459", "map_id": "none", "name": "SLC6A14 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10045484", "map_id": "A0A3Q1MNF2", "name": "SLC6A14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000083685", "map_id": "ENSBTAT00000083685", "name": "SLC6A14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045473", "map_id": "none", "name": "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_375409", "map_id": "none", "name": "Gly, L-Pro", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_375414", "map_id": "none", "name": "Gly, L-Pro", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10045470", "map_id": "E1BGG5", "name": "SLC36A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000027731", "map_id": "ENSBTAT00000027731", "name": "SLC36A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044962", "map_id": "none", "name": "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044959", "map_id": "Q0VCM6", "name": "SLC43A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000015260", "map_id": "ENSBTAT00000015260", "name": "SLC43A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044964", "map_id": "none", "name": "SLC38A2 (ATA2)-mediated uptake of neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_352091", "map_id": "none", "name": "ligands of SLC38A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_352088", "map_id": "none", "name": "ligands of SLC38A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044458", "map_id": "A2VE31", "name": "SLC38A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014749", "map_id": "ENSBTAT00000014749", "name": "SLC38A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044934", "map_id": "none", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266029", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10044931", "map_id": "E1BHC0", "name": "SLC6A18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000016676", "map_id": "ENSBTAT00000016676", "name": "SLC6A18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039272", "map_id": "none", "name": "beta-NGF dimer binds to TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10039264", "map_id": "none", "name": "mature beta-NGF homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LP06", "map_id": "A0A3Q1LP06", "name": "NGF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076924", "map_id": "ENSBTAT00000076924", "name": "NGF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039258", "map_id": "A0A3Q1MJ18", "name": "NTRK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000067057", "map_id": "ENSBTAT00000067057", "name": "phospho-NTRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039266", "map_id": "none", "name": "beta-NGF dimer:TrkA receptor", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MJ18", "map_id": "A0A3Q1MJ18", "name": "phospho-NTRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040684", "map_id": "none", "name": "Activated TrkA receptor internalizes to endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039569", "map_id": "none", "name": "Activated TrkA receptor complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10039684", "map_id": "none", "name": "Activated TrkA receptor complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10039270", "map_id": "none", "name": "The bound receptor dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039268", "map_id": "none", "name": "beta-NGF dimer:TrkA receptor dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10088473", "map_id": "none", "name": "FAM20C phosphorylates FAM20C substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10088246", "map_id": "none", "name": "FAM20C:FAM20C substrates", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A3Q1N5X6", "map_id": "A0A3Q1N5X6", "name": "FAM20C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080120", "map_id": "ENSBTAT00000080120", "name": "FAM20C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11116", "map_id": "P11116", "name": "phospho-LGALS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020080", "map_id": "ENSBTAT00000020080", "name": "phospho-LGALS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP39", "map_id": "A6QP39", "name": "phospho-MSLN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000202", "map_id": "ENSBTAT00000000202", "name": "phospho-MSLN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG36", "map_id": "E1BG36", "name": "phospho-MEPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009958", "map_id": "ENSBTAT00000009958", "name": "phospho-MEPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG25", "map_id": "E1BG25", "name": "phospho-MELTF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046533", "map_id": "ENSBTAT00000046533", "name": "phospho-MELTF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FUZ9", "map_id": "A4FUZ9", "name": "phospho-APOA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026336", "map_id": "ENSBTAT00000026336", "name": "phospho-APOA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MS36", "map_id": "A0A3Q1MS36", "name": "phospho-NOTUM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076629", "map_id": "ENSBTAT00000076629", "name": "phospho-NOTUM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DII7", "map_id": "A0A452DII7", "name": "phospho-MXRA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016252", "map_id": "ENSBTAT00000016252", "name": "phospho-MXRA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5H2", "map_id": "F1N5H2", "name": "phospho-FUCA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002297", "map_id": "ENSBTAT00000002297", "name": "phospho-FUCA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKR5", "map_id": "F1MKR5", "name": "phospho-ENAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013661", "map_id": "ENSBTAT00000013661", "name": "phospho-ENAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N3Y2", "map_id": "A0A3Q1N3Y2", "name": "phospho-HRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073105", "map_id": "ENSBTAT00000073105", "name": "phospho-HRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBZ6", "map_id": "Q3ZBZ6", "name": "GPC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027192", "map_id": "ENSBTAT00000027192", "name": "GPC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLA8", "map_id": "E1BLA8", "name": "phospho-GOLM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044756", "map_id": "ENSBTAT00000044756", "name": "phospho-GOLM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05717", "map_id": "Q05717", "name": "phospho-IGFBP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078855", "map_id": "ENSBTAT00000078855", "name": "phospho-IGFBP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P20959", "map_id": "P20959", "name": "phospho-IGFBP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053426", "map_id": "ENSBTAT00000053426", "name": "phospho-IGFBP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P24591", "map_id": "P24591", "name": "phospho-IGFBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064194", "map_id": "ENSBTAT00000064194", "name": "phospho-IGFBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q95M18", "map_id": "Q95M18", "name": "phospho-HSP90B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004364", "map_id": "ENSBTAT00000004364", "name": "phospho-HSP90B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P26892", "map_id": "P26892", "name": "phospho-IL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019865", "map_id": "ENSBTAT00000019865", "name": "phospho-IL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPP2", "map_id": "F1MPP2", "name": "phospho-IGFBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025803", "map_id": "ENSBTAT00000025803", "name": "phospho-IGFBP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MI67", "map_id": "F1MI67", "name": "phospho-BPIFB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025557", "map_id": "ENSBTAT00000025557", "name": "phospho-BPIFB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RJ01", "map_id": "F6RJ01", "name": "phospho-p-TGOLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027753", "map_id": "ENSBTAT00000027753", "name": "phospho-p-TGOLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJH1", "map_id": "Q2KJH1", "name": "phospho-BMP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004992", "map_id": "ENSBTAT00000004992", "name": "phospho-BMP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X6N3", "map_id": "G3X6N3", "name": "TF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6PX77", "map_id": "Q6PX77", "name": "phospho-BMP15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064918", "map_id": "ENSBTAT00000064918", "name": "phospho-BMP15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8P3", "map_id": "E1B8P3", "name": "phospho-STC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002384", "map_id": "ENSBTAT00000002384", "name": "phospho-STC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ03", "map_id": "A0A452DJ03", "name": "phospho-VWA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028372", "map_id": "ENSBTAT00000028372", "name": "phospho-VWA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A5H1ZRH6", "map_id": "A0A5H1ZRH6", "name": "phospho-CDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028238", "map_id": "ENSBTAT00000028238", "name": "phospho-CDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BH06", "map_id": "E1BH06", "name": "C4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009019", "map_id": "ENSBTAT00000009019", "name": "C4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVK1", "map_id": "F1MVK1", "name": "LOC107131209", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045468", "map_id": "ENSBTAT00000045468", "name": "LOC107131209", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEA1", "map_id": "F1MEA1", "name": "phospho-TMEM132A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024433", "map_id": "ENSBTAT00000024433", "name": "phospho-TMEM132A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMK4", "map_id": "A0A3Q1LMK4", "name": "phospho-CSF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076179", "map_id": "ENSBTAT00000076179", "name": "phospho-CSF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N348", "map_id": "G3N348", "name": "phospho-WFS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082028", "map_id": "ENSBTAT00000082028", "name": "phospho-WFS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ME65", "map_id": "F1ME65", "name": "CKAP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015804", "map_id": "ENSBTAT00000015804", "name": "CKAP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MAZ4", "map_id": "F1MAZ4", "name": "phospho-CHRDL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005810", "map_id": "ENSBTAT00000005810", "name": "phospho-CHRDL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRR3", "map_id": "A0A3Q1LRR3", "name": "phospho-CCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074422", "map_id": "ENSBTAT00000074422", "name": "phospho-CCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01035", "map_id": "P01035", "name": "phospho-CST3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000790", "map_id": "ENSBTAT00000000790", "name": "phospho-CST3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QH94", "map_id": "F6QH94", "name": "phospho-PDIA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002508", "map_id": "ENSBTAT00000002508", "name": "phospho-PDIA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHZ5", "map_id": "A0A452DHZ5", "name": "phospho-NUCB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003073", "map_id": "ENSBTAT00000003073", "name": "phospho-NUCB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1LZE9", "map_id": "Q1LZE9", "name": "phospho-PRSS23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020194", "map_id": "ENSBTAT00000020194", "name": "phospho-PRSS23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01211", "map_id": "P01211", "name": "phospho-PENK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087134", "map_id": "ENSBTAT00000087134", "name": "phospho-PENK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NJR8", "map_id": "A0A3Q1NJR8", "name": "phospho-SERPINC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071014", "map_id": "ENSBTAT00000071014", "name": "phospho-SERPINC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2L2", "map_id": "G3N2L2", "name": "phospho-RCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063521", "map_id": "ENSBTAT00000063521", "name": "phospho-RCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MEX5", "map_id": "A0A3Q1MEX5", "name": "phospho-LOC531557", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072231", "map_id": "ENSBTAT00000072231", "name": "phospho-LOC531557", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QPR4", "map_id": "A6QPR4", "name": "phospho-APOL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044682", "map_id": "ENSBTAT00000044682", "name": "phospho-APOL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2W6", "map_id": "G3N2W6", "name": "phospho-p-APOL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065790", "map_id": "ENSBTAT00000065790", "name": "phospho-p-APOL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NAS1", "map_id": "A0A3Q1NAS1", "name": "phospho-LOC788334", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074235", "map_id": "ENSBTAT00000074235", "name": "phospho-LOC788334", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQR3", "map_id": "A6QQR3", "name": "phospho-APOL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X724", "map_id": "G3X724", "name": "phospho-p-APOL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NIX0", "map_id": "A0A3Q1NIX0", "name": "phospho-LOC786352", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078756", "map_id": "ENSBTAT00000078756", "name": "phospho-LOC786352", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHJ7", "map_id": "E1BHJ7", "name": "phospho-LOC112446726", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016190", "map_id": "ENSBTAT00000016190", "name": "phospho-LOC112446726", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MB94", "map_id": "A0A3Q1MB94", "name": "phospho-LOC518495", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069263", "map_id": "ENSBTAT00000069263", "name": "phospho-LOC518495", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP86", "map_id": "A6QP86", "name": "phospho-LOC510193", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054074", "map_id": "ENSBTAT00000054074", "name": "phospho-LOC510193", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QSG5", "map_id": "F6QSG5", "name": "phospho-LOC515697", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056456", "map_id": "ENSBTAT00000056456", "name": "phospho-LOC515697", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LIS3", "map_id": "A0A3Q1LIS3", "name": "phospho-SPARCL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085388", "map_id": "ENSBTAT00000085388", "name": "phospho-SPARCL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P81644", "map_id": "P81644", "name": "phospho-APOA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012138", "map_id": "ENSBTAT00000012138", "name": "phospho-APOA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MD94", "map_id": "F1MD94", "name": "phospho-MATN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027836", "map_id": "ENSBTAT00000027836", "name": "phospho-MATN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVS2", "map_id": "A0A3Q1LVS2", "name": "KTN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069650", "map_id": "ENSBTAT00000069650", "name": "KTN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MY30", "map_id": "A0A3Q1MY30", "name": "phospho-LAMB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082437", "map_id": "ENSBTAT00000082437", "name": "phospho-LAMB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P02817", "map_id": "P02817", "name": "phospho-AMELX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016034", "map_id": "ENSBTAT00000016034", "name": "phospho-AMELX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDK6", "map_id": "E1BDK6", "name": "phospho-LAMB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057452", "map_id": "ENSBTAT00000057452", "name": "phospho-LAMB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJF8", "map_id": "E1BJF8", "name": "ANO8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022706", "map_id": "ENSBTAT00000022706", "name": "ANO8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MD77", "map_id": "F1MD77", "name": "phospho-LAMC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015881", "map_id": "ENSBTAT00000015881", "name": "phospho-LAMC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8931885", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10088464", "map_id": "none", "name": "FAM20C:Phosphorylated FAM20C substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_8931884", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10088471", "map_id": "none", "name": "FAM20C:FAM20A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1MJW4", "map_id": "F1MJW4", "name": "FAM20A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001439", "map_id": "ENSBTAT00000001439", "name": "FAM20A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046621", "map_id": "none", "name": "IGFBP1 binds IGF forming IGF:IGFBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046613", "map_id": "P07455", "name": "IGF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046617", "map_id": "P24591", "name": "IGFBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046619", "map_id": "none", "name": "IGF:IGFBP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10068959", "map_id": "none", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068951", "map_id": "G3N0Y4", "name": "UBN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000064363", "map_id": "ENSBTAT00000064363", "name": "UBN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068947", "map_id": "A0A3Q1NMK6", "name": "HIRA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000074434", "map_id": "ENSBTAT00000074434", "name": "HIRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068943", "map_id": "Q2KIG1", "name": "ASF1A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000002664", "map_id": "ENSBTAT00000002664", "name": "ASF1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068955", "map_id": "G3X746", "name": "CABIN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000018360", "map_id": "ENSBTAT00000018360", "name": "CABIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068957", "map_id": "none", "name": "HIRA:ASF1A:UBN1:CABIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3X746", "map_id": "G3X746", "name": "CABIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIG1", "map_id": "Q2KIG1", "name": "ASF1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NMK6", "map_id": "A0A3Q1NMK6", "name": "HIRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N0Y4", "map_id": "G3N0Y4", "name": "UBN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061480", "map_id": "none", "name": "Trans-autophosphorylation of ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061477", "map_id": "none", "name": "NRGs/EGFLs:ERBB4:ERBB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCQ7", "map_id": "F1MCQ7", "name": "phospho-ERBB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029056", "map_id": "ENSBTAT00000029056", "name": "phospho-ERBB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057121", "map_id": "none", "name": "NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10061469", "map_id": "none", "name": "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061466", "map_id": "none", "name": "NRGs/EGFLs:ERBB4:p-Y877-ERBB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057130", "map_id": "none", "name": "NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057692", "map_id": "none", "name": "GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057688", "map_id": "none", "name": "Phosphorylated ERBB2:ERBB4 heterodimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057690", "map_id": "none", "name": "NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057695", "map_id": "none", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10086415", "map_id": "none", "name": "SHC1 binds PTPN12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084846", "map_id": "A0A3Q1M0B4", "name": "PTPN12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000068950", "map_id": "ENSBTAT00000068950", "name": "PTPN12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086408", "map_id": "Q0IIE2", "name": "phospho-SHC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086413", "map_id": "none", "name": "p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2:PTPN12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M0B4", "map_id": "A0A3Q1M0B4", "name": "PTPN12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057139", "map_id": "none", "name": "SHC1 phosphorylation by ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057134", "map_id": "none", "name": "SHC1:Phosphorylated ERBB2 heterodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057136", "map_id": "none", "name": "p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083483", "map_id": "none", "name": "ERBB2 promotes PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083475", "map_id": "none", "name": "p-ERBB2 heterodimers:PTK6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057132", "map_id": "none", "name": "p-ERBB2 heterodimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083477", "map_id": "none", "name": "Activated ERBB2 binds PTK6 (BRK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083473", "map_id": "E1BNA8", "name": "PTK6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10057700", "map_id": "none", "name": "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057697", "map_id": "none", "name": "NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077601", "map_id": "none", "name": "Phosphorylated ERBB2 heterodimers bind MEMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077597", "map_id": "A0A3Q1N5P3", "name": "MEMO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000085928", "map_id": "ENSBTAT00000085928", "name": "MEMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077599", "map_id": "none", "name": "p-ERBB2 heterodimers:MEMO1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N5P3", "map_id": "A0A3Q1N5P3", "name": "MEMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077605", "map_id": "none", "name": "MEMO1 binds RHOA:GTP:DIAPH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073537", "map_id": "none", "name": "RHOA:GTP:DIAPH1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LUD9", "map_id": "A0A3Q1LUD9", "name": "DIAPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083004", "map_id": "ENSBTAT00000083004", "name": "DIAPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077603", "map_id": "none", "name": "p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084849", "map_id": "none", "name": "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084842", "map_id": "none", "name": "Heterodimers of p-ERBB2 dephosphorylated at Y1248", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10061458", "map_id": "none", "name": "MATK (CSK homologous kinase) binds phosphorylated ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061454", "map_id": "Q58D16", "name": "MATK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000069379", "map_id": "ENSBTAT00000069379", "name": "MATK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10061456", "map_id": "none", "name": "p-ERBB2 heterodimers:MATK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q58D16", "map_id": "Q58D16", "name": "MATK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057740", "map_id": "none", "name": "Deubiquitination of RNF41 by P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057737", "map_id": "none", "name": "Ub-RNF41:p-USP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2KI91", "map_id": "Q2KI91", "name": "RNF41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087037", "map_id": "ENSBTAT00000087037", "name": "RNF41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0IIM6", "map_id": "Q0IIM6", "name": "phospho-USP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033814", "map_id": "ENSBTAT00000033814", "name": "phospho-USP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055232", "map_id": "Q2KI91", "name": "RNF41", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057726", "map_id": "Q0IIM6", "name": "phospho-USP8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10057742", "map_id": "none", "name": "Ubiquitinated RNF41 binds P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057709", "map_id": "none", "name": "Ub-RNF41", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10057744", "map_id": "none", "name": "ERBB3 binds RNF41 ubiquitin ligase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057066", "map_id": "A6QR62", "name": "ERBB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000013790", "map_id": "ENSBTAT00000013790", "name": "ERBB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057714", "map_id": "none", "name": "ERBB3:RNF41", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QR62", "map_id": "A6QR62", "name": "ERBB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057712", "map_id": "none", "name": "Self-ubiquitination of RNF41", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10057719", "map_id": "none", "name": "RNF41 ubiquitinates ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057716", "map_id": "none", "name": "Ub-ERBB3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057735", "map_id": "none", "name": "RNF41 ubiquitinates activated ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057730", "map_id": "none", "name": "NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057732", "map_id": "none", "name": "NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10061492", "map_id": "none", "name": "SRC family kinases phosphorylate ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061489", "map_id": "none", "name": "p-Y419/420/426-N-myristoyl-SRC/FYN/YES1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066602", "map_id": "none", "name": "SLC52A1,2,3 transport RIB from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3165253", "map_id": "CHEBI:17015", "name": "RIB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_196931", "map_id": "CHEBI:17015", "name": "RIB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066599", "map_id": "none", "name": "SLC52A1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N6I5", "map_id": "A0A3Q1N6I5", "name": "SLC52A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083852", "map_id": "ENSBTAT00000083852", "name": "SLC52A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9R1", "map_id": "Q5E9R1", "name": "SLC52A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084768", "map_id": "ENSBTAT00000084768", "name": "SLC52A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_73524", "map_id": "CHEBI:17621", "name": "FMN", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29386", "map_id": "CHEBI:16238", "name": "FAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041772", "map_id": "none", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041769", "map_id": "A0A3Q1MPJ2", "name": "FLAD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081315", "map_id": "ENSBTAT00000081315", "name": "FLAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041790", "map_id": "none", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041787", "map_id": "none", "name": "2xENPP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MNS5", "map_id": "F1MNS5", "name": "ENPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061365", "map_id": "ENSBTAT00000061365", "name": "ENPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041781", "map_id": "none", "name": "2xTRAP hydrolyzes FMN to RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041778", "map_id": "none", "name": "2xTRAP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B8A0", "map_id": "E1B8A0", "name": "ACP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006339", "map_id": "ENSBTAT00000006339", "name": "ACP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041799", "map_id": "none", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041796", "map_id": "none", "name": "RFK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6R223", "map_id": "F6R223", "name": "RFK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025762", "map_id": "ENSBTAT00000025762", "name": "RFK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056185", "map_id": "none", "name": "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056174", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1ME65", "map_id": "A0A3Q1ME65", "name": "STAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084342", "map_id": "ENSBTAT00000084342", "name": "STAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJQ3", "map_id": "E1BJQ3", "name": "IL6R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024587", "map_id": "ENSBTAT00000024587", "name": "IL6R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056180", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056183", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9BEG9", "map_id": "Q9BEG9", "name": "SOCS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011106", "map_id": "ENSBTAT00000011106", "name": "SOCS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056123", "map_id": "none", "name": "Assembly of hexameric IL-6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056119", "map_id": "none", "name": "IL6 receptor trimer:JAKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056121", "map_id": "none", "name": "IL6 receptor hexamer:JAKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056188", "map_id": "none", "name": "Phosphorylated STATs are released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056166", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051764", "map_id": "A0A3Q1ME65", "name": "phospho-STAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056127", "map_id": "none", "name": "IL6 binds IL6R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056113", "map_id": "E1BJQ3", "name": "IL6R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10056094", "map_id": "P26892", "name": "IL6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10056115", "map_id": "none", "name": "IL6:IL6R", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056125", "map_id": "none", "name": "IL6R:IL6R inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056176", "map_id": "none", "name": "Tyrosine phosphorylated IL6ST binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046556", "map_id": "A0A3Q1ME65", "name": "STAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056178", "map_id": "none", "name": "STAT1 and STAT3 dimers translocate to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051766", "map_id": "none", "name": "p-Y701-STAT1-1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052345", "map_id": "none", "name": "p-Y701-STAT1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056201", "map_id": "none", "name": "PTPN11 binds p-Y759-IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056190", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056168", "map_id": "none", "name": "IL6ST is tyrosine phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056149", "map_id": "none", "name": "IL6 receptor hexamer:Activated JAKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056170", "map_id": "none", "name": "JAK activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10056205", "map_id": "none", "name": "Serine phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056203", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056172", "map_id": "none", "name": "Phosphorylated STAT1, STAT3 form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10056207", "map_id": "none", "name": "SOCS3 binds IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051731", "map_id": "Q9BEG9", "name": "SOCS3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056110", "map_id": "none", "name": "IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049958", "map_id": "none", "name": "IL6ST:JAK1, JAK2, (TYK2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056100", "map_id": "none", "name": "IL6:IL6R-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10056104", "map_id": "none", "name": "IL6:sIL6R:IL6RB:JAKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056108", "map_id": "none", "name": "IL6:IL6R-2:IL6ST-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10091747", "map_id": "none", "name": "IL6R binds IL6R inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9715042", "map_id": "none", "name": "IL6R inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10056130", "map_id": "none", "name": "IL6:IL6R-2 binds IL6ST-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10056106", "map_id": "E1BD36", "name": "IL6ST", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10056194", "map_id": "none", "name": "PTPN11 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040359", "map_id": "A0A3Q1LN00", "name": "CBL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072559", "map_id": "ENSBTAT00000072559", "name": "phospho-CBL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056192", "map_id": "none", "name": "Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11:CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LN00", "map_id": "A0A3Q1LN00", "name": "phospho-CBL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056132", "map_id": "none", "name": "IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056117", "map_id": "none", "name": "IL6:IL6RA:IL6RB:JAKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056199", "map_id": "none", "name": "PTPN11 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056196", "map_id": "none", "name": "IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056102", "map_id": "none", "name": "IL6 binds IL6R-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10056098", "map_id": "E1BJQ3", "name": "IL6R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10087338", "map_id": "none", "name": "IL36RN, IL1F10 bind IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10087334", "map_id": "none", "name": "IL36RN, IL1F10", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MWT5", "map_id": "F1MWT5", "name": "IL36RN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023970", "map_id": "ENSBTAT00000023970", "name": "IL36RN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD32", "map_id": "E1BD32", "name": "IL1F10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023975", "map_id": "ENSBTAT00000023975", "name": "IL1F10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083514", "map_id": "F1N3K3", "name": "IL1RL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000007489", "map_id": "ENSBTAT00000007489", "name": "IL1RL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087336", "map_id": "none", "name": "IL36RN,IL1F10:IL1RL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N3K3", "map_id": "F1N3K3", "name": "IL1RL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083522", "map_id": "none", "name": "IL36 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083510", "map_id": "none", "name": "IL36A,IL36B,IL36G", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "G3MX81", "map_id": "G3MX81", "name": "IL36A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065203", "map_id": "ENSBTAT00000065203", "name": "IL36A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2N4", "map_id": "F1N2N4", "name": "IL36B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002696", "map_id": "ENSBTAT00000002696", "name": "IL36B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYY4", "map_id": "F1MYY4", "name": "IL36G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045402", "map_id": "ENSBTAT00000045402", "name": "IL36G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083516", "map_id": "none", "name": "IL36:IL1RL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10083520", "map_id": "F1MWT5", "name": "IL36RN", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10050024", "map_id": "none", "name": "CTSG cleaves CASP1(1-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050013", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072083", "map_id": "ENSBTAT00000072083", "name": "CASP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050007", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050005", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050017", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050015", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050021", "map_id": "E1BAD2", "name": "LOC505658", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10050011", "map_id": "none", "name": "Formation of caspase-1 p10/p20 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050009", "map_id": "none", "name": "CASP1(120-197):CASP1(317-404)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MFA5", "map_id": "A0A3Q1MFA5", "name": "CASP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050028", "map_id": "none", "name": "Caspase-1 active tetramer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050026", "map_id": "none", "name": "Caspase-1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089595", "map_id": "none", "name": "IL1F10 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10087332", "map_id": "E1BD32", "name": "IL1F10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10089593", "map_id": "none", "name": "IL1F10:IL1RL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089597", "map_id": "none", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037699", "map_id": "A0A3Q1LWJ8", "name": "MAPK8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039514", "map_id": "A0A3Q1LWJ8", "name": "phospho-MAPK8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089591", "map_id": "none", "name": "IL1F10 is cleaved", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10089589", "map_id": "E1BD32", "name": "IL1F10", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10089587", "map_id": "E1BD32", "name": "IL1F10", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10089625", "map_id": "none", "name": "IL37(?-218) translocates from the cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089617", "map_id": "E1BLE5", "name": "IL37", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000029311", "map_id": "ENSBTAT00000029311", "name": "IL37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089623", "map_id": "E1BLE5", "name": "IL37", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10089819", "map_id": "none", "name": "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089810", "map_id": "none", "name": "IL37:2x(CASP1(120-197):CASP1(317-404))", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BLE5", "map_id": "E1BLE5", "name": "IL37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089816", "map_id": "none", "name": "IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089615", "map_id": "none", "name": "TBK1 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053189", "map_id": "E1BKP4", "name": "TBK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023134", "map_id": "ENSBTAT00000023134", "name": "phospho-TBK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089613", "map_id": "E1BKP4", "name": "phospho-TBK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083537", "map_id": "none", "name": "IL37 binds IL18R1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083527", "map_id": "F1MJ29", "name": "IL18R1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001371", "map_id": "ENSBTAT00000001371", "name": "IL18R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083531", "map_id": "E1BLE5", "name": "IL37", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083535", "map_id": "none", "name": "IL18R1:IL37,IL37(?-218)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MJ29", "map_id": "F1MJ29", "name": "IL18R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089843", "map_id": "none", "name": "IL37(1-?) and IL37 (?-) dissocates from IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089814", "map_id": "E1BLE5", "name": "IL37", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089621", "map_id": "none", "name": "IL37, IL37(?-218) translocates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089619", "map_id": "E1BLE5", "name": "IL37", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089812", "map_id": "none", "name": "IL37 binds 2x(CASP1(120-197):CASP1(317-404))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10049721", "map_id": "none", "name": "IL1 receptor antagonist protein binds Interleukin 1 receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049717", "map_id": "A0A3Q1MKE9", "name": "IL1RN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000087066", "map_id": "ENSBTAT00000087066", "name": "IL1RN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049713", "map_id": "none", "name": "IL1R1:IL1R2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1ML75", "map_id": "F1ML75", "name": "IL1R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006938", "map_id": "ENSBTAT00000006938", "name": "IL1R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIE7", "map_id": "Q2KIE7", "name": "IL1R2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008322", "map_id": "ENSBTAT00000008322", "name": "IL1R2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049719", "map_id": "none", "name": "IL1R1:IL1R2:IL1RN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MKE9", "map_id": "A0A3Q1MKE9", "name": "IL1RN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043867", "map_id": "none", "name": "IKBA is phosphorylated by Phospho IKKB kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043854", "map_id": "Q8WNW7", "name": "NFKBIA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022183", "map_id": "ENSBTAT00000022183", "name": "phospho-NFKBIA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043858", "map_id": "Q8WNW7", "name": "phospho-NFKBIA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043864", "map_id": "Q95KV0", "name": "phospho-IKBKB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009995", "map_id": "ENSBTAT00000009995", "name": "phospho-IKBKB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091757", "map_id": "none", "name": "IL1R1 binds IL1R1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9681804", "map_id": "none", "name": "IL1R1 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049707", "map_id": "F1ML75", "name": "IL1R1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10091755", "map_id": "none", "name": "IL1R1:IL1R1 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050428", "map_id": "none", "name": "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050418", "map_id": "none", "name": "IRAK4: Pellino-1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1RMT8", "map_id": "Q1RMT8", "name": "IRAK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028115", "map_id": "ENSBTAT00000028115", "name": "IRAK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQ14", "map_id": "A0A3Q1LQ14", "name": "phospho-PELI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067567", "map_id": "ENSBTAT00000067567", "name": "phospho-PELI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050425", "map_id": "none", "name": "IRAK4: p-Pellino-1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050420", "map_id": "none", "name": "hp-IRAK1,hp-IRAK4 bind Pellino1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050416", "map_id": "A0A3Q1LQ14", "name": "PELI2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050412", "map_id": "Q1RMT8", "name": "IRAK4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10051095", "map_id": "none", "name": "p62:MEKK3 binds to TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051091", "map_id": "none", "name": "MAP3K3:SQSTM1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LPF2", "map_id": "A0A3Q1LPF2", "name": "MAP3K3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081015", "map_id": "ENSBTAT00000081015", "name": "MAP3K3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051093", "map_id": "none", "name": "MAP3K3:SQSTM1:TRAF6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10085017", "map_id": "none", "name": "BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084951", "map_id": "F1MTQ0", "name": "BRWD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000018087", "map_id": "ENSBTAT00000018087", "name": "BRWD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085013", "map_id": "none", "name": "AcK(9,14,18,79)-p(S10,T11)-histone H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P68432", "map_id": "P68432", "name": "MeK10-HIST1H3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087179", "map_id": "ENSBTAT00000087179", "name": "MeK10-HIST1H3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P84227", "map_id": "P84227", "name": "MeK-HIST2H3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079615", "map_id": "ENSBTAT00000079615", "name": "MeK-HIST2H3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085015", "map_id": "none", "name": "BRWD1:AcK(9,14,18,79)-p(S10,T11)-histone H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MTQ0", "map_id": "F1MTQ0", "name": "BRWD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091731", "map_id": "none", "name": "JAK3 binds JAK3 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050577", "map_id": "E1BEL4", "name": "JAK3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000027857", "map_id": "ENSBTAT00000027857", "name": "JAK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9678772", "map_id": "none", "name": "JAK3 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091729", "map_id": "none", "name": "JAK3:JAK3 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BEL4", "map_id": "E1BEL4", "name": "JAK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089251", "map_id": "none", "name": "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089244", "map_id": "none", "name": "IL7R:TSLP:CRLF2:STAT3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BPM3", "map_id": "E1BPM3", "name": "IL7R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026608", "map_id": "ENSBTAT00000026608", "name": "IL7R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7G0", "map_id": "G3X7G0", "name": "LOC529792", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026955", "map_id": "ENSBTAT00000026955", "name": "LOC529792", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5G1", "map_id": "A0A3Q1M5G1", "name": "TSLP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072042", "map_id": "ENSBTAT00000072042", "name": "TSLP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089248", "map_id": "none", "name": "IL7R:TSLP:CRLF2:p-STAT3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089253", "map_id": "none", "name": "TSLP binds CRLF2:IL7R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10089234", "map_id": "A0A3Q1M5G1", "name": "TSLP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10089240", "map_id": "none", "name": "CRLF2:IL7R", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089242", "map_id": "none", "name": "IL7R:TSLP:CRLF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087787", "map_id": "none", "name": "CRLF1:IL27 translocates to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087772", "map_id": "none", "name": "CRLF1:IL27", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MQM6", "map_id": "A0A3Q1MQM6", "name": "CRLF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074594", "map_id": "ENSBTAT00000074594", "name": "CRLF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LK84", "map_id": "A0A3Q1LK84", "name": "IL27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083936", "map_id": "ENSBTAT00000083936", "name": "IL27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087785", "map_id": "none", "name": "CRLF1:IL27", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10049946", "map_id": "none", "name": "Interleukin-27 translocates from the ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049938", "map_id": "none", "name": "IL27:EBI3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A6QPV0", "map_id": "A6QPV0", "name": "EBI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017046", "map_id": "ENSBTAT00000017046", "name": "EBI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049944", "map_id": "none", "name": "IL27:EBI3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10087726", "map_id": "none", "name": "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10087711", "map_id": "none", "name": "IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5D7S4", "map_id": "A5D7S4", "name": "IL27RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022524", "map_id": "ENSBTAT00000022524", "name": "IL27RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087723", "map_id": "none", "name": "IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087774", "map_id": "none", "name": "IL27 binds CRLF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087770", "map_id": "A0A3Q1LK84", "name": "IL27", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10087768", "map_id": "A0A3Q1MQM6", "name": "CRLF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10087793", "map_id": "none", "name": "IL27RA dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049962", "map_id": "A5D7S4", "name": "IL27RA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10087791", "map_id": "none", "name": "2xIL27RA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049970", "map_id": "none", "name": "Interleukin-27 binds Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049964", "map_id": "none", "name": "IL27RA:JAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049966", "map_id": "none", "name": "IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049968", "map_id": "A5D7S4", "name": "IL27RA", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10087671", "map_id": "none", "name": "Interleukin-27 dissociates from Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049940", "map_id": "A0A3Q1LK84", "name": "IL27", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10087783", "map_id": "none", "name": "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10087766", "map_id": "none", "name": "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087736", "map_id": "none", "name": "IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10087734", "map_id": "none", "name": "p-Y701-STAT1:p-Y705-STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089321", "map_id": "none", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089313", "map_id": "none", "name": "IL-35:(IL6ST:JAK1:JAK2) dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089319", "map_id": "none", "name": "IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089329", "map_id": "none", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089325", "map_id": "none", "name": "IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089327", "map_id": "none", "name": "IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089331", "map_id": "none", "name": "STAT1 associates with IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089323", "map_id": "none", "name": "IL-35:(IL6ST:p-JAK1:p-JAK2) dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087763", "map_id": "none", "name": "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087752", "map_id": "none", "name": "IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10087760", "map_id": "none", "name": "IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089333", "map_id": "none", "name": "p-STAT1 dissociates from IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10087758", "map_id": "A0A3Q1ME65", "name": "phospho-STAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10087780", "map_id": "none", "name": "p-STAT1:p-STAT4 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087776", "map_id": "none", "name": "p-STAT1:p-STAT4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087778", "map_id": "none", "name": "p-Y693-STAT4:p-Y701-STAT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10049928", "map_id": "none", "name": "Interleukin-23 binds interleukin-23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049924", "map_id": "none", "name": "IL23R:JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MZJ0", "map_id": "F1MZJ0", "name": "phospho-IL23R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019945", "map_id": "ENSBTAT00000019945", "name": "phospho-IL23R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049904", "map_id": "none", "name": "IL12B:IL23A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MSN4", "map_id": "F1MSN4", "name": "IL23A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005745", "map_id": "ENSBTAT00000005745", "name": "IL23A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049914", "map_id": "none", "name": "IL12RB1:TYK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049926", "map_id": "none", "name": "IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087789", "map_id": "none", "name": "IL12B:IL23A translocates from ER lumen to extracellular space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10087669", "map_id": "none", "name": "IL12B:IL23A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087697", "map_id": "none", "name": "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087690", "map_id": "none", "name": "IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3:STAT4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10087694", "map_id": "none", "name": "IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:p-Y705-STAT3:p-Y693-STAT4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10088498", "map_id": "none", "name": "STAT4 binds p-Y-IL23R in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087674", "map_id": "F1N0R2", "name": "STAT4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10087688", "map_id": "none", "name": "IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051194", "map_id": "none", "name": "PTK2B is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051187", "map_id": "none", "name": "JAK3:PYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LVP1", "map_id": "A0A3Q1LVP1", "name": "phospho-PTK2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084967", "map_id": "ENSBTAT00000084967", "name": "phospho-PTK2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051192", "map_id": "none", "name": "JAK3:p-PYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051196", "map_id": "none", "name": "PTK2B binds JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047260", "map_id": "A0A3Q1LVP1", "name": "PTK2B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10050527", "map_id": "none", "name": "IL2RB binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050134", "map_id": "A0A3Q1LQZ1", "name": "IL2RB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000074166", "map_id": "ENSBTAT00000074166", "name": "phospho-IL2RB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049950", "map_id": "F1N0D6", "name": "JAK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050136", "map_id": "none", "name": "IL2RB:JAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LQZ1", "map_id": "A0A3Q1LQZ1", "name": "phospho-IL2RB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089736", "map_id": "none", "name": "IL9R binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089732", "map_id": "F1MTF9", "name": "IL9R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000009944", "map_id": "ENSBTAT00000009944", "name": "IL9R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089734", "map_id": "none", "name": "IL9R:JAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MTF9", "map_id": "F1MTF9", "name": "IL9R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089363", "map_id": "none", "name": "p-Y701-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089359", "map_id": "A0A3Q1ME65", "name": "phospho-STAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089361", "map_id": "none", "name": "p-Y-STAT1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050619", "map_id": "none", "name": "Phosphorylated SHC1 recruits GRB2:GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050571", "map_id": "none", "name": "GRB2:GAB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10050569", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MXH7", "map_id": "F1MXH7", "name": "phospho-CSF2RB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011947", "map_id": "ENSBTAT00000011947", "name": "phospho-CSF2RB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LK34", "map_id": "A0A3Q1LK34", "name": "IL3RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085850", "map_id": "ENSBTAT00000085850", "name": "IL3RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MB14", "map_id": "A0A3Q1MB14", "name": "CSF2RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040022", "map_id": "ENSBTAT00000040022", "name": "CSF2RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11052", "map_id": "P11052", "name": "CSF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002054", "map_id": "ENSBTAT00000002054", "name": "CSF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050617", "map_id": "none", "name": "Interleukin receptor compexes with activated Shc:GRB2:GAB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A2VE30", "map_id": "A2VE30", "name": "IL2RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054113", "map_id": "ENSBTAT00000054113", "name": "IL2RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050623", "map_id": "none", "name": "Phosphorylated SHC recruits GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050621", "map_id": "none", "name": "Interleukin receptor complexes with activated SHC1:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052254", "map_id": "none", "name": "SHC1 mediates cytokine-induced phosphorylation of GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10052252", "map_id": "none", "name": "Interleukin receptor complexes with activated Shc:GRB2:p-GAB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052337", "map_id": "none", "name": "Phosphorylated SHC1 recruits SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052333", "map_id": "none", "name": "SHIP1,2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BBJ7", "map_id": "E1BBJ7", "name": "INPPL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025510", "map_id": "ENSBTAT00000025510", "name": "INPPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJT8", "map_id": "A0A3Q1LJT8", "name": "INPP5D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077857", "map_id": "ENSBTAT00000077857", "name": "INPP5D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052335", "map_id": "none", "name": "Interleukin receptor complexes with activated SHC1:SHIP1,2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052343", "map_id": "none", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052339", "map_id": "none", "name": "Interleukin receptor complexes with activated SHC1:SHIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M739", "map_id": "A0A3Q1M739", "name": "PTPN6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077529", "map_id": "ENSBTAT00000077529", "name": "PTPN6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035485", "map_id": "Q3T0F9", "name": "GRB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10052341", "map_id": "none", "name": "Interleukin receptor complexes with activated SHC1:SHIP:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089291", "map_id": "none", "name": "IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "species_10089255", "map_id": "none", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q28028", "map_id": "Q28028", "name": "IL15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084366", "map_id": "ENSBTAT00000084366", "name": "IL15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M783", "map_id": "A0A3Q1M783", "name": "IL15RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083836", "map_id": "ENSBTAT00000083836", "name": "IL15RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089289", "map_id": "none", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17940", "compartment_display": "endosome", "complex": "true" }, { "id": "reaction_10089311", "map_id": "none", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089307", "map_id": "none", "name": "SOS1, SOS2", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089305", "map_id": "none", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089309", "map_id": "none", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:SOS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089267", "map_id": "none", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089264", "map_id": "none", "name": "IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089269", "map_id": "none", "name": "IL15 binds IL15RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10050128", "map_id": "A0A3Q1M783", "name": "IL15RA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10050124", "map_id": "Q28028", "name": "IL15", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10050130", "map_id": "none", "name": "IL15:IL15RA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089689", "map_id": "none", "name": "IL34:CSF1 binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10089685", "map_id": "none", "name": "IL34:CSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A6QL48", "map_id": "A6QL48", "name": "IL34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076664", "map_id": "ENSBTAT00000076664", "name": "IL34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077839", "map_id": "A7Z067", "name": "CSF1R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000016977", "map_id": "ENSBTAT00000016977", "name": "CSF1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089687", "map_id": "none", "name": "IL34:CSF1:CSF1R", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7Z067", "map_id": "A7Z067", "name": "CSF1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089691", "map_id": "none", "name": "IL34 binds CSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10089683", "map_id": "A0A3Q1LMK4", "name": "CSF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049979", "map_id": "A6QL48", "name": "IL34", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10090027", "map_id": "none", "name": "TXLNA (IL14) binds syntaxin3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10090023", "map_id": "A0A3Q1LYB4", "name": "STX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000069233", "map_id": "ENSBTAT00000069233", "name": "STX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050140", "map_id": "E1BGS4", "name": "TXLNA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000017100", "map_id": "ENSBTAT00000017100", "name": "TXLNA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090025", "map_id": "none", "name": "TXLNA:STX3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BGS4", "map_id": "E1BGS4", "name": "TXLNA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYB4", "map_id": "A0A3Q1LYB4", "name": "STX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049983", "map_id": "none", "name": "IL34 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049981", "map_id": "none", "name": "IL34 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090031", "map_id": "none", "name": "TXLNA (IL14) binds syntaxin4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10090029", "map_id": "none", "name": "TXLNA:STX4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077843", "map_id": "none", "name": "IL34 dimer binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10077841", "map_id": "none", "name": "CSF1R:IL34 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077945", "map_id": "none", "name": "Expression of HSP90B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060767", "map_id": "Q95M18", "name": "HSP90B1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10077723", "map_id": "none", "name": "p-Y705-STAT3, p-Y641-STAT6 dimerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077719", "map_id": "F1MGJ4", "name": "phospho-STAT6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008311", "map_id": "ENSBTAT00000008311", "name": "phospho-STAT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077721", "map_id": "none", "name": "p-Y641-STAT6 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MGJ4", "map_id": "F1MGJ4", "name": "phospho-STAT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077870", "map_id": "none", "name": "p-Y-STATs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077866", "map_id": "none", "name": "p-Y701-STAT1,p-Y705-STAT3,p-Y641-STAT6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10077868", "map_id": "none", "name": "p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y641-STAT6 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077633", "map_id": "none", "name": "IL13RA1 binds TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049908", "map_id": "F1MCX4", "name": "TYK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077629", "map_id": "G3X7E9", "name": "IL13RA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000025754", "map_id": "ENSBTAT00000025754", "name": "IL13RA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077631", "map_id": "none", "name": "IL13RA1:TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3X7E9", "map_id": "G3X7E9", "name": "IL13RA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077874", "map_id": "none", "name": "p-Y-STATs translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077872", "map_id": "none", "name": "p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y641-STAT6 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077764", "map_id": "none", "name": "p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077762", "map_id": "none", "name": "p-Y641-STAT6 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10052302", "map_id": "none", "name": "CBL:CRKL binds RAPGEF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052298", "map_id": "none", "name": "p(Y700,731,774)-CBL:CRK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N016", "map_id": "G3N016", "name": "CRKL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066024", "map_id": "ENSBTAT00000066024", "name": "CRKL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BQ32", "map_id": "E1BQ32", "name": "CRK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007443", "map_id": "ENSBTAT00000007443", "name": "CRK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039707", "map_id": "A0A3Q1LXN8", "name": "RAPGEF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000066818", "map_id": "ENSBTAT00000066818", "name": "RAPGEF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052300", "map_id": "none", "name": "p(Y700,731,774)-CBL:CRK:RAPGEF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LXN8", "map_id": "A0A3Q1LXN8", "name": "RAPGEF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052323", "map_id": "none", "name": "CBL binds CRK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052267", "map_id": "A0A3Q1LN00", "name": "phospho-CBL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10052296", "map_id": "none", "name": "CRK, CRKL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10052294", "map_id": "none", "name": "CBL ubiquitinates PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052288", "map_id": "none", "name": "K48polyUb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052269", "map_id": "none", "name": "FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052292", "map_id": "none", "name": "FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051962", "map_id": "none", "name": "Recruitment of SHC1 is mediated by Y593 of the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051923", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051960", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051949", "map_id": "none", "name": "Activation of STAT5a/b by JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051942", "map_id": "none", "name": "High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051946", "map_id": "none", "name": "High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052735", "map_id": "none", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10052238", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10052732", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051966", "map_id": "none", "name": "The receptor is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051964", "map_id": "none", "name": "High affinity binding complexes of interleukin receptors using the Common beta chain", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051921", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052321", "map_id": "none", "name": "p-S585-IL3RB binds 14-3-3 proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037660", "map_id": "P63103", "name": "YWHAZ", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000000289", "map_id": "ENSBTAT00000000289", "name": "YWHAZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052317", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10052319", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P63103", "map_id": "P63103", "name": "YWHAZ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051936", "map_id": "none", "name": "Tyrosine kinases phosphorylate the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051933", "map_id": "none", "name": "Tyrosine kinases that phosphorylate the Common beta chain", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052240", "map_id": "none", "name": "SHP1 and SHP2 bind the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047046", "map_id": "none", "name": "PTPN6,PTPN11", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051954", "map_id": "none", "name": "JAK2 is phosphorylated, activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051951", "map_id": "none", "name": "High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052325", "map_id": "none", "name": "GM-CSF receptor alpha subunit binds GM-CSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10050559", "map_id": "P11052", "name": "CSF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10050555", "map_id": "A0A3Q1MB14", "name": "CSF2RA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10050561", "map_id": "none", "name": "GM-CSF:GM-CSF receptor alpha subunit", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052327", "map_id": "none", "name": "GM-CSF receptor alpha:GM-CSF binds Bc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051911", "map_id": "none", "name": "IL3RB:JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051917", "map_id": "none", "name": "GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089466", "map_id": "none", "name": "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089459", "map_id": "none", "name": "IL19:IL20RA:JAK1:IL20RB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M5P5", "map_id": "A0A3Q1M5P5", "name": "IL20RA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066507", "map_id": "ENSBTAT00000066507", "name": "IL20RA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNP0", "map_id": "A6QNP0", "name": "IL20RB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010919", "map_id": "ENSBTAT00000010919", "name": "IL20RB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089463", "map_id": "none", "name": "IL19:IL20RA:p-JAK1:IL20RB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089530", "map_id": "none", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089527", "map_id": "none", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MZC4", "map_id": "G3MZC4", "name": "IFNL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063825", "map_id": "ENSBTAT00000063825", "name": "IFNL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7G0", "map_id": "E1B7G0", "name": "phospho-IFNLR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001456", "map_id": "ENSBTAT00000001456", "name": "phospho-IFNLR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089450", "map_id": "none", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089523", "map_id": "none", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089520", "map_id": "none", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089490", "map_id": "none", "name": "IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089427", "map_id": "none", "name": "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_459", "compartment_display": "cytoplasm" }, { "id": "species_10089417", "map_id": "none", "name": "IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B8Z4", "map_id": "E1B8Z4", "name": "STAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005749", "map_id": "ENSBTAT00000005749", "name": "STAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089424", "map_id": "none", "name": "IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089431", "map_id": "none", "name": "p-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089429", "map_id": "none", "name": "2 x p-STAT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089480", "map_id": "none", "name": "IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089476", "map_id": "none", "name": "IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089478", "map_id": "none", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089453", "map_id": "none", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089413", "map_id": "none", "name": "IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089516", "map_id": "none", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089513", "map_id": "none", "name": "IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1,p-STAT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089455", "map_id": "none", "name": "IL22RA1 binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050036", "map_id": "F1MJR4", "name": "IL22RA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001455", "map_id": "ENSBTAT00000001455", "name": "IL22RA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050038", "map_id": "none", "name": "IL22RA1:JAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MJR4", "map_id": "F1MJR4", "name": "IL22RA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089536", "map_id": "none", "name": "p-STAT1 dimer translocates from the cytosol to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089534", "map_id": "none", "name": "2 x p-STAT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089538", "map_id": "none", "name": "IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089518", "map_id": "none", "name": "JAK2, JAK3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089484", "map_id": "none", "name": "IL20:IL20RA:JAK1:IL20RB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089442", "map_id": "none", "name": "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089435", "map_id": "none", "name": "IL24:IL22RA1:JAK1:IL20RB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089439", "map_id": "none", "name": "IL24:IL22RA1:p-JAK1:IL20RB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089506", "map_id": "none", "name": "JAK1 binds IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049999", "map_id": "E1B7G0", "name": "IFNLR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10050001", "map_id": "none", "name": "IFNLR1:JAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089540", "map_id": "none", "name": "IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089415", "map_id": "none", "name": "STAT1, STAT2, STAT3, STAT4, STAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089444", "map_id": "none", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089422", "map_id": "none", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4,p-STAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089511", "map_id": "none", "name": "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089508", "map_id": "none", "name": "IL24:IL20RA:JAK1:IL20RB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089446", "map_id": "none", "name": "JAK1 binds IL20RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050044", "map_id": "A0A3Q1M5P5", "name": "IL20RA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10050046", "map_id": "none", "name": "IL20RA:JAK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050054", "map_id": "none", "name": "IL20RA binds IL20RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10050032", "map_id": "A6QNP0", "name": "IL20RB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10050048", "map_id": "none", "name": "IL20RA:JAK1:IL20RB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089542", "map_id": "none", "name": "p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061449", "map_id": "none", "name": "Mature NOTCH heterodimer traffics to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10061434", "map_id": "none", "name": "NOTCH4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "G3X812", "map_id": "G3X812", "name": "phospho-NOTCH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050083", "map_id": "ENSBTAT00000050083", "name": "phospho-NOTCH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10061443", "map_id": "none", "name": "NOTCH4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10061447", "map_id": "A0A3Q1MFR6", "name": "TMED2", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "ENSBTAT00000084118", "map_id": "ENSBTAT00000084118", "name": "TMED2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090834", "map_id": "none", "name": "NICD4 traffics to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10090824", "map_id": "G3X812", "name": "NOTCH4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044414", "map_id": "G3X812", "name": "NOTCH4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10090832", "map_id": "none", "name": "p-4S-NICD4:YWHAZ dimer", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10078393", "map_id": "none", "name": "LIPT2 transfers octanoyl group to GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10078383", "map_id": "none", "name": "octanoyl:NDUFAB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:25650", "map_id": "CHEBI:25650", "name": "CHEBI:25650", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X6L0", "map_id": "G3X6L0", "name": "phospho-NDUFAB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076429", "map_id": "P20821", "name": "GCSH", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000008936", "map_id": "ENSBTAT00000008936", "name": "GCSH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038774", "map_id": "G3X6L0", "name": "NDUFAB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10078386", "map_id": "P20821", "name": "GCSH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078390", "map_id": "E1BI46", "name": "LIPT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000010820", "map_id": "ENSBTAT00000010820", "name": "LIPT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052056", "map_id": "none", "name": "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_379697", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159549", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10052053", "map_id": "none", "name": "AGXT2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F1MLG7", "map_id": "F1MLG7", "name": "AGXT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010113", "map_id": "ENSBTAT00000010113", "name": "AGXT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047019", "map_id": "none", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389822", "map_id": "CHEBI:29805", "name": "glycolate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389678", "map_id": "CHEBI:16891", "name": "glyoxylate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10047016", "map_id": "none", "name": "HAO1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "E1BC79", "map_id": "E1BC79", "name": "HAO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061291", "map_id": "ENSBTAT00000061291", "name": "HAO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078701", "map_id": "none", "name": "GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5359017", "map_id": "CHEBI:15611", "name": "SARC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10078698", "map_id": "none", "name": "GNMT tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LMP5", "map_id": "A0A3Q1LMP5", "name": "GNMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079667", "map_id": "ENSBTAT00000079667", "name": "GNMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M678", "map_id": "A0A3Q1M678", "name": "LOC112443696", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080669", "map_id": "ENSBTAT00000080669", "name": "LOC112443696", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047022", "map_id": "none", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389819", "map_id": "CHEBI:16995", "name": "OX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10078366", "map_id": "none", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10078353", "map_id": "A0A3Q1M6S6", "name": "DHTKD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000079686", "map_id": "ENSBTAT00000079686", "name": "DHTKD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076427", "map_id": "P20821", "name": "GCSH", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078359", "map_id": "A0A3Q1M6S6", "name": "DHTKD1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078363", "map_id": "O46419", "name": "LIPT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000005171", "map_id": "ENSBTAT00000005171", "name": "LIPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077458", "map_id": "none", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784236", "map_id": "CHEBI:32812", "name": "4-OH-L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6784229", "map_id": "CHEBI:17742", "name": "HOG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113553", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033725", "map_id": "none", "name": "GOT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P12344", "map_id": "P12344", "name": "GOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009440", "map_id": "ENSBTAT00000009440", "name": "GOT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078402", "map_id": "none", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6793610", "map_id": "CHEBI:26833", "name": "S", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162265", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379705", "map_id": "CHEBI:57844", "name": "L-Met", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6793613", "map_id": "CHEBI:17319", "name": "5dAde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078399", "map_id": "none", "name": "LIAS:2(4Fe-4S)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q5BIP7", "map_id": "Q5BIP7", "name": "LIAS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019299", "map_id": "ENSBTAT00000019299", "name": "LIAS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:49883", "map_id": "CHEBI:49883", "name": "CHEBI:49883", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076441", "map_id": "none", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10076431", "map_id": "none", "name": "GCSH:SAMDLL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P20821", "map_id": "P20821", "name": "GCSH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:14949", "map_id": "CHEBI:14949", "name": "CHEBI:14949", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076438", "map_id": "none", "name": "PXLP-K754-GLDC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BJQ1", "map_id": "E1BJQ1", "name": "GLDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036700", "map_id": "ENSBTAT00000036700", "name": "GLDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076459", "map_id": "none", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10076443", "map_id": "none", "name": "GCSH:DHLL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:50746", "map_id": "CHEBI:50746", "name": "CHEBI:50746", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076456", "map_id": "none", "name": "DLD dimer:2xFAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F1N206", "map_id": "F1N206", "name": "DLD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033787", "map_id": "ENSBTAT00000033787", "name": "DLD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076450", "map_id": "none", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_200671", "map_id": "CHEBI:15635", "name": "THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693984", "map_id": "CHEBI:12071", "name": "5,10-methylene-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076447", "map_id": "P25285", "name": "AMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000002992", "map_id": "ENSBTAT00000002992", "name": "AMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051737", "map_id": "none", "name": "Transphosphorylation of JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051716", "map_id": "none", "name": "IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LLQ7", "map_id": "A0A3Q1LLQ7", "name": "IFNGR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066996", "map_id": "ENSBTAT00000066996", "name": "IFNGR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07353", "map_id": "P07353", "name": "IFNG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016634", "map_id": "ENSBTAT00000016634", "name": "IFNG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051722", "map_id": "none", "name": "IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043836", "map_id": "A0A3Q1M739", "name": "PTPN6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051735", "map_id": "none", "name": "IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MSN0", "map_id": "F1MSN0", "name": "SOCS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005753", "map_id": "ENSBTAT00000005753", "name": "SOCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091723", "map_id": "none", "name": "IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678984", "map_id": "none", "name": "JAK1,2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051743", "map_id": "none", "name": "IFNGR1:JAK1:INFGR2:JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051778", "map_id": "none", "name": "IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051771", "map_id": "none", "name": "Phosphorylation of STAT1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051760", "map_id": "none", "name": "STAT1 bound to p-IFNGR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051768", "map_id": "none", "name": "p-STAT1(Y701) bound to p-IFNGR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051786", "map_id": "none", "name": "Release of STAT1 dimer from active receptor unit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051784", "map_id": "none", "name": "p-STAT1 dimer bound to p-IFNGR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051756", "map_id": "none", "name": "IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051690", "map_id": "none", "name": "IFNG-activated factor (GAF)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051774", "map_id": "none", "name": "Phosphorylation of IFNGR1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10051696", "map_id": "none", "name": "Translocation of STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10051694", "map_id": "none", "name": "IFNG-activated factor (GAF)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10052067", "map_id": "none", "name": "Phosphorylation of STAT1 at Ser727", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052064", "map_id": "none", "name": "CaMKII and PKC-delta", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MRR6", "map_id": "A0A3Q1MRR6", "name": "phospho-PRKCD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078659", "map_id": "ENSBTAT00000078659", "name": "phospho-PRKCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKC7", "map_id": "A0A3Q1MKC7", "name": "phospho-CAMK2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073084", "map_id": "ENSBTAT00000073084", "name": "phospho-CAMK2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M066", "map_id": "A0A3Q1M066", "name": "phospho-CAMK2G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071596", "map_id": "ENSBTAT00000071596", "name": "phospho-CAMK2G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051762", "map_id": "none", "name": "Binding of STAT1 to p-IFNGR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051758", "map_id": "A0A3Q1ME65", "name": "STAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10051818", "map_id": "none", "name": "PIAS1 binds p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10051814", "map_id": "none", "name": "Homologues of SUMO1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M137", "map_id": "A0A3Q1M137", "name": "SUMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084456", "map_id": "ENSBTAT00000084456", "name": "SUMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2W5", "map_id": "A0A3Q1M2W5", "name": "SUMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4Y4", "map_id": "A0A3Q1M4Y4", "name": "SUMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MRS5", "map_id": "A0A3Q1MRS5", "name": "SUMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051796", "map_id": "A0A3Q1ML58", "name": "PIAS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000083334", "map_id": "ENSBTAT00000083334", "name": "PIAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051816", "map_id": "none", "name": "p-STAT1 dimer:PIAS:SUMO1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1ML58", "map_id": "A0A3Q1ML58", "name": "PIAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055967", "map_id": "none", "name": "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055960", "map_id": "A0A3Q1ME65", "name": "STAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10055964", "map_id": "A0A3Q1MPM2", "name": "PTPN2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000074168", "map_id": "ENSBTAT00000074168", "name": "PTPN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051792", "map_id": "none", "name": "SOCS-1 and SOCS-3 binds to p-JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051733", "map_id": "none", "name": "SOCS-1 and SOCS-3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051780", "map_id": "none", "name": "IFNG dimer binds IFNGR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10051702", "map_id": "none", "name": "IFNG dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10051745", "map_id": "none", "name": "IFNG:IFNGR1:JAK1:IFNGR2:JAK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051776", "map_id": "none", "name": "IFNG dimer:IFNG inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10051748", "map_id": "none", "name": "Phosphorylation of JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10078682", "map_id": "none", "name": "PRTPRF, PTPRS, PTPRD bind LRRC4B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078678", "map_id": "E1BPK8", "name": "LRRC4B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000043330", "map_id": "ENSBTAT00000043330", "name": "LRRC4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046864", "map_id": "none", "name": "PTPRF, PTPRS, PTPRD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M422", "map_id": "A0A3Q1M422", "name": "PTPRD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066459", "map_id": "ENSBTAT00000066459", "name": "PTPRD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MZF8", "map_id": "A0A3Q1MZF8", "name": "PTPRS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074444", "map_id": "ENSBTAT00000074444", "name": "PTPRS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078680", "map_id": "none", "name": "LRRC4B:PTPRF,PTPRS,PTPRD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BPK8", "map_id": "E1BPK8", "name": "LRRC4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078674", "map_id": "none", "name": "PTPRS binds NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046862", "map_id": "A0A3Q1MZF8", "name": "PTPRS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10078670", "map_id": "G3N3T6", "name": "NTRK3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064547", "map_id": "ENSBTAT00000064547", "name": "phospho-NTRK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078672", "map_id": "none", "name": "PTPRS:NTRK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N3T6", "map_id": "G3N3T6", "name": "phospho-NTRK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046868", "map_id": "none", "name": "PTPRF, PTPRS, PTPRD bind Liprins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046854", "map_id": "none", "name": "Liprins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MBH3", "map_id": "A0A3Q1MBH3", "name": "PPFIA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073078", "map_id": "ENSBTAT00000073078", "name": "PPFIA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5L6", "map_id": "A0A3Q1M5L6", "name": "PPFIA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081984", "map_id": "ENSBTAT00000081984", "name": "PPFIA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQ22", "map_id": "A0A3Q1LQ22", "name": "PPFIA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075872", "map_id": "ENSBTAT00000075872", "name": "PPFIA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5X2", "map_id": "A0A3Q1M5X2", "name": "PPFIBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069454", "map_id": "ENSBTAT00000069454", "name": "PPFIBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046866", "map_id": "none", "name": "LAR,PTPRS,PTPRD:Liprins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078566", "map_id": "none", "name": "PTPRD binds SLITRK1-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078562", "map_id": "none", "name": "SLITRK1-6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N5L8", "map_id": "F1N5L8", "name": "SLITRK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015639", "map_id": "ENSBTAT00000015639", "name": "SLITRK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJJ9", "map_id": "F1MJJ9", "name": "SLITRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054494", "map_id": "ENSBTAT00000054494", "name": "SLITRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8X9", "map_id": "E1B8X9", "name": "SLITRK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013364", "map_id": "ENSBTAT00000013364", "name": "SLITRK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2N1", "map_id": "G3N2N1", "name": "SLITRK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072588", "map_id": "ENSBTAT00000072588", "name": "SLITRK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSM8", "map_id": "F1MSM8", "name": "SLITRK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005757", "map_id": "ENSBTAT00000005757", "name": "SLITRK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N513", "map_id": "F1N513", "name": "SLITRK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022827", "map_id": "ENSBTAT00000022827", "name": "SLITRK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046858", "map_id": "A0A3Q1M422", "name": "PTPRD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10078564", "map_id": "none", "name": "SLITRK1-6:PTPRD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10034944", "map_id": "none", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73578", "map_id": "CHEBI:78679", "name": "R5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73566", "map_id": "CHEBI:17111", "name": "PRPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034941", "map_id": "none", "name": "PRPS2 dimer, PRPS1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2HJ58", "map_id": "Q2HJ58", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026261", "map_id": "ENSBTAT00000026261", "name": "PRPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036903", "map_id": "none", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_110644", "map_id": "CHEBI:16284", "name": "dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109386", "map_id": "CHEBI:17713", "name": "2'-deoxyadenosine 5'-monophosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10034933", "map_id": "none", "name": "PRPS1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076792", "map_id": "none", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694568", "map_id": "CHEBI:61232", "name": "NAPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694580", "map_id": "CHEBI:52571", "name": "GPAEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694567", "map_id": "CHEBI:22221", "name": "acyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10076789", "map_id": "A0A452DIS9", "name": "ABHD4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000022154", "map_id": "ENSBTAT00000022154", "name": "ABHD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059002", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500581", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498738", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524021", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10058940", "map_id": "none", "name": "PLA2(9)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NMD6", "map_id": "A0A3Q1NMD6", "name": "PLA2G16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078451", "map_id": "ENSBTAT00000078451", "name": "PLA2G16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LR65", "map_id": "A0A3Q1LR65", "name": "PLA2G4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067227", "map_id": "ENSBTAT00000067227", "name": "PLA2G4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYR5", "map_id": "A0A3Q1LYR5", "name": "PLA2G4E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078489", "map_id": "ENSBTAT00000078489", "name": "PLA2G4E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MG30", "map_id": "F1MG30", "name": "PLA2G4D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003576", "map_id": "ENSBTAT00000003576", "name": "PLA2G4D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MNU5", "map_id": "F1MNU5", "name": "PLA2G4F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006775", "map_id": "ENSBTAT00000006775", "name": "PLA2G4F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059853", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_1602372", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602366", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10059844", "map_id": "none", "name": "PLA2(16)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MSG5", "map_id": "F1MSG5", "name": "PLA2G2E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005791", "map_id": "ENSBTAT00000005791", "name": "PLA2G2E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGU4", "map_id": "E1BGU4", "name": "PLA2G10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028684", "map_id": "ENSBTAT00000028684", "name": "PLA2G10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JZ2", "map_id": "Q56JZ2", "name": "PLA2G2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007570", "map_id": "ENSBTAT00000007570", "name": "PLA2G2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFE1", "map_id": "A0A3Q1MFE1", "name": "PLA2G2F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078105", "map_id": "ENSBTAT00000078105", "name": "PLA2G2F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7L0", "map_id": "A5D7L0", "name": "PLA2G12A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020263", "map_id": "ENSBTAT00000020263", "name": "PLA2G12A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MNU5", "map_id": "A0A3Q1MNU5", "name": "LOC112443425", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080344", "map_id": "ENSBTAT00000080344", "name": "LOC112443425", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5P6", "map_id": "A0A3Q1M5P6", "name": "PLA2G5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077544", "map_id": "ENSBTAT00000077544", "name": "PLA2G5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059004", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058967", "map_id": "none", "name": "PLA2(6)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BE78", "map_id": "E1BE78", "name": "PNPLA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017658", "map_id": "ENSBTAT00000017658", "name": "PNPLA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084526", "map_id": "none", "name": "HRASLS transfer acyl group from PC to PE to form NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426925", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6814253", "map_id": "CHEBI:58168", "name": "LysoPtdCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10084523", "map_id": "none", "name": "HRASLS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10058899", "map_id": "none", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058882", "map_id": "none", "name": "LPEAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G8JL05", "map_id": "G8JL05", "name": "LPCAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054491", "map_id": "ENSBTAT00000054491", "name": "LPCAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MH02", "map_id": "F1MH02", "name": "MBOAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010729", "map_id": "ENSBTAT00000010729", "name": "MBOAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058885", "map_id": "none", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498729", "map_id": "CHEBI:28936", "name": "2-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058980", "map_id": "none", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058977", "map_id": "none", "name": "PLA2(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10046888", "map_id": "none", "name": "PD-1 binds B7DC and B7H1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046882", "map_id": "none", "name": "B7-DC,B7-H1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M2W6", "map_id": "A0A3Q1M2W6", "name": "PDCD1LG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083184", "map_id": "ENSBTAT00000083184", "name": "PDCD1LG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C5NU11", "map_id": "C5NU11", "name": "CD274", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008067", "map_id": "ENSBTAT00000008067", "name": "CD274", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046872", "map_id": "A0A3Q1MQR6", "name": "PDCD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000079165", "map_id": "ENSBTAT00000079165", "name": "PDCD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046884", "map_id": "none", "name": "PDCD1:B7-DC,B7-H1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MQR6", "map_id": "A0A3Q1MQR6", "name": "PDCD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046886", "map_id": "none", "name": "PDCD1:PDCD1 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091743", "map_id": "none", "name": "PDCD1 binds PDCD1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9679406", "map_id": "none", "name": "PDCD1 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10064439", "map_id": "none", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2161525", "map_id": "none", "name": "abacavir", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2161185", "map_id": "none", "name": "abacavir", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051266", "map_id": "none", "name": "OCT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7MBE0", "map_id": "A7MBE0", "name": "SLC22A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004059", "map_id": "ENSBTAT00000004059", "name": "SLC22A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064584", "map_id": "none", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2162081", "map_id": "CHEBI:64192", "name": "abacavir 5'-carboxylic acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034181", "map_id": "none", "name": "ADH1A:2Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZP8", "map_id": "F1MZP8", "name": "ADH1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009185", "map_id": "ENSBTAT00000009185", "name": "ADH1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075063", "map_id": "none", "name": "GRB2-1:SOS1 binds p-3Y-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050549", "map_id": "Q0IIE2", "name": "phospho-SHC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075061", "map_id": "none", "name": "GRB2-1:SOS1:p-3Y-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10086241", "map_id": "none", "name": "RUNX3 binds the NOTCH1 coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084943", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000070567", "map_id": "ENSBTAT00000070567", "name": "RUNX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086237", "map_id": "none", "name": "NOTCH1 Coactivator Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MF28", "map_id": "A0A3Q1MF28", "name": "MAML1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078064", "map_id": "ENSBTAT00000078064", "name": "MAML1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQE0", "map_id": "Q1JQE0", "name": "SNW1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010697", "map_id": "ENSBTAT00000010697", "name": "SNW1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ41", "map_id": "Q3SZ41", "name": "RBPJ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004696", "map_id": "ENSBTAT00000004696", "name": "RBPJ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8D6", "map_id": "E1B8D6", "name": "EP300", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021556", "map_id": "ENSBTAT00000021556", "name": "EP300", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MLT2", "map_id": "A0A3Q1MLT2", "name": "KAT2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075969", "map_id": "ENSBTAT00000075969", "name": "KAT2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MD32", "map_id": "F1MD32", "name": "CREBBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005092", "map_id": "ENSBTAT00000005092", "name": "CREBBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086239", "map_id": "none", "name": "RUNX3:NOTCH1 Coactivator Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MYL2", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072913", "map_id": "none", "name": "p-4Y-PLCG1 dissociates from activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072911", "map_id": "none", "name": "activated FGFR3:p-4Y-PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MYF9", "map_id": "F1MYF9", "name": "PLCG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023383", "map_id": "ENSBTAT00000023383", "name": "PLCG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043237", "map_id": "F1MYF9", "name": "phospho-PLCG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10065265", "map_id": "none", "name": "Activated FGFR3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072944", "map_id": "none", "name": "Activated FGFR3 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072941", "map_id": "none", "name": "activated FGFR3:PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072946", "map_id": "none", "name": "Activated FGFR3 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061098", "map_id": "F1MYF9", "name": "PLCG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10073152", "map_id": "none", "name": "Activated FGFR3 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073138", "map_id": "none", "name": "Activated FGFR3:SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073149", "map_id": "none", "name": "Activated FGFR3:pY-SHC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073140", "map_id": "none", "name": "Activated FGFR3 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073156", "map_id": "none", "name": "Activated FGFR3:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073154", "map_id": "none", "name": "Activated FGFR3:pY-SHC1:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073159", "map_id": "none", "name": "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073234", "map_id": "none", "name": "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065273", "map_id": "none", "name": "Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073145", "map_id": "none", "name": "Activated FGFR3 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073142", "map_id": "none", "name": "Activated FGFR3:p-FRS:PTPN11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10065269", "map_id": "none", "name": "Activated FGFR3:p-FRS2:p-PTPN11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073019", "map_id": "none", "name": "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073016", "map_id": "none", "name": "Activated FGFR3:p-FRS:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073147", "map_id": "none", "name": "Activated FGFR3:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065267", "map_id": "none", "name": "Activated FGFR3:p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073021", "map_id": "none", "name": "Activated FGFR3:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10087376", "map_id": "none", "name": "Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073011", "map_id": "none", "name": "Activated FGFR3 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073006", "map_id": "none", "name": "Activated FGFR3:FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073009", "map_id": "none", "name": "Activated FGFR3:p-8T-FRS2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073014", "map_id": "none", "name": "Activated FGFR3 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072959", "map_id": "E1B7I9", "name": "FRS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10062984", "map_id": "none", "name": "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10062948", "map_id": "none", "name": "Heparan(4)-PGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "F1MZX8", "map_id": "F1MZX8", "name": "GPC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011475", "map_id": "ENSBTAT00000011475", "name": "GPC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MER7", "map_id": "F1MER7", "name": "HSPG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N5R3", "map_id": "A0A3Q1N5R3", "name": "SDC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082452", "map_id": "ENSBTAT00000082452", "name": "SDC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTY7", "map_id": "A0A3Q1LTY7", "name": "AGRN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085269", "map_id": "ENSBTAT00000085269", "name": "AGRN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZ29", "map_id": "A0A3Q1LZ29", "name": "GPC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082766", "map_id": "ENSBTAT00000082766", "name": "GPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKS1", "map_id": "E1BKS1", "name": "SDC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020125", "map_id": "ENSBTAT00000020125", "name": "SDC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062971", "map_id": "none", "name": "HS(1)-PGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062981", "map_id": "none", "name": "NDSTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A8E4L2", "map_id": "A8E4L2", "name": "NDST2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080227", "map_id": "ENSBTAT00000080227", "name": "NDST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063610", "map_id": "none", "name": "HS2ST1 sulfates IdoA at C2 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063045", "map_id": "none", "name": "HS(2)-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063068", "map_id": "none", "name": "HS(3)-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063607", "map_id": "A0A3Q1M8D2", "name": "HS2ST1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000086518", "map_id": "ENSBTAT00000086518", "name": "HS2ST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063633", "map_id": "none", "name": "HS3STs sulfate GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063091", "map_id": "none", "name": "HS(4)-PGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063630", "map_id": "none", "name": "HS3STs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q0VD21", "map_id": "Q0VD21", "name": "HS3ST5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085321", "map_id": "ENSBTAT00000085321", "name": "HS3ST5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B729", "map_id": "E1B729", "name": "HS3ST6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025630", "map_id": "ENSBTAT00000025630", "name": "HS3ST6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKQ1", "map_id": "E1BKQ1", "name": "HS3ST2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023123", "map_id": "ENSBTAT00000023123", "name": "HS3ST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNJ7", "map_id": "E1BNJ7", "name": "HS3ST3A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044024", "map_id": "ENSBTAT00000044024", "name": "HS3ST3A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BP03", "map_id": "E1BP03", "name": "HS3ST3B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010350", "map_id": "ENSBTAT00000010350", "name": "HS3ST3B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063216", "map_id": "none", "name": "Some HSPGs are secreted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10063132", "map_id": "none", "name": "HSPGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063214", "map_id": "none", "name": "HSPGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10063603", "map_id": "none", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063114", "map_id": "none", "name": "HS(5)-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063130", "map_id": "none", "name": "HS/HPIN-PGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063600", "map_id": "none", "name": "HS6STs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1LS54", "map_id": "A0A3Q1LS54", "name": "HS6ST2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078465", "map_id": "ENSBTAT00000078465", "name": "HS6ST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTK3", "map_id": "A0A3Q1LTK3", "name": "HS6ST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075020", "map_id": "ENSBTAT00000075020", "name": "HS6ST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063010", "map_id": "none", "name": "NDST1-4 N-deacetylates GlcNAc residues in heparan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_2022884", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10063007", "map_id": "none", "name": "Heparan(3)-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063586", "map_id": "none", "name": "HS3ST1 sulfates GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10063583", "map_id": "none", "name": "HS3ST sulfotransferases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "Q0VCB5", "map_id": "Q0VCB5", "name": "HS3ST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009799", "map_id": "ENSBTAT00000009799", "name": "HS3ST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051589", "map_id": "none", "name": "SLC35D2 exchanges UDP-sugars for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_744229", "map_id": "none", "name": "UDP-GlcNAc, UDP-Glc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_735698", "map_id": "CHEBI:16695", "name": "uridine 5'-monophosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_744234", "map_id": "none", "name": "UDP-GlcNAc, UDP-Glc", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10051584", "map_id": "E1BM02", "name": "SLC35D2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000026562", "map_id": "ENSBTAT00000026562", "name": "SLC35D2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084090", "map_id": "none", "name": "PHLDA1 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084086", "map_id": "Q2TA06", "name": "AURKA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084084", "map_id": "F6Q0F9", "name": "PHLDA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000011655", "map_id": "ENSBTAT00000011655", "name": "phospho-PHLDA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084088", "map_id": "none", "name": "AURKA:PHLDA1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6Q0F9", "map_id": "F6Q0F9", "name": "phospho-PHLDA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084096", "map_id": "none", "name": "AURKA phosphorylates PHLDA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084093", "map_id": "F6Q0F9", "name": "phospho-PHLDA1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10076112", "map_id": "none", "name": "MYSM1 deubiquitinates Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076107", "map_id": "none", "name": "MYSM1:EP300:KAT2B:Ub-histone H2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MUE2", "map_id": "A0A3Q1MUE2", "name": "MYSM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080652", "map_id": "ENSBTAT00000080652", "name": "MYSM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036828", "map_id": "none", "name": "Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10076109", "map_id": "none", "name": "MYSM1:EP300:KAT2B:Histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076119", "map_id": "none", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039539", "map_id": "none", "name": "K63polyUb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039537", "map_id": "none", "name": "K63-Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10076116", "map_id": "Q17QP9", "name": "PSMD14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000046166", "map_id": "ENSBTAT00000046166", "name": "PSMD14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089947", "map_id": "none", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089943", "map_id": "none", "name": "RHOC effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LHF1", "map_id": "A0A3Q1LHF1", "name": "DAAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075877", "map_id": "ENSBTAT00000075877", "name": "DAAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSX9", "map_id": "A0A3Q1LSX9", "name": "FMNL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073284", "map_id": "ENSBTAT00000073284", "name": "FMNL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LM61", "map_id": "A0A3Q1LM61", "name": "PKN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075730", "map_id": "ENSBTAT00000075730", "name": "PKN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV55", "map_id": "A0A3Q1LV55", "name": "CIT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079495", "map_id": "ENSBTAT00000079495", "name": "CIT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073483", "map_id": "none", "name": "RHOC:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q1RMJ6", "map_id": "Q1RMJ6", "name": "RHOC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018998", "map_id": "ENSBTAT00000018998", "name": "RHOC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089945", "map_id": "none", "name": "RHOC:GTP:RHOC effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092364", "map_id": "none", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092362", "map_id": "none", "name": "RHOC:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10089937", "map_id": "none", "name": "RHOC GEFs activate RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089932", "map_id": "none", "name": "RHOC:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089934", "map_id": "none", "name": "RHOC GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LUW4", "map_id": "A0A3Q1LUW4", "name": "AKAP13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069851", "map_id": "ENSBTAT00000069851", "name": "AKAP13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N6F4", "map_id": "A0A3Q1N6F4", "name": "ARHGEF25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072165", "map_id": "ENSBTAT00000072165", "name": "ARHGEF25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQP9", "map_id": "A0A3Q1MQP9", "name": "VAV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086853", "map_id": "ENSBTAT00000086853", "name": "VAV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MRV3", "map_id": "A0A3Q1MRV3", "name": "LOC112445816", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083879", "map_id": "ENSBTAT00000083879", "name": "LOC112445816", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LFQ5", "map_id": "A0A3Q1LFQ5", "name": "ARHGEF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066417", "map_id": "ENSBTAT00000066417", "name": "ARHGEF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MN47", "map_id": "A0A3Q1MN47", "name": "ARHGEF12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081099", "map_id": "ENSBTAT00000081099", "name": "ARHGEF12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LKT3", "map_id": "A0A3Q1LKT3", "name": "ARHGEF28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074225", "map_id": "ENSBTAT00000074225", "name": "ARHGEF28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNE2", "map_id": "A0A3Q1LNE2", "name": "ARHGEF11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077218", "map_id": "ENSBTAT00000077218", "name": "ARHGEF11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQ45", "map_id": "A0A3Q1LQ45", "name": "MCF2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078928", "map_id": "ENSBTAT00000078928", "name": "MCF2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2G5", "map_id": "F1N2G5", "name": "ARHGEF5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002373", "map_id": "ENSBTAT00000002373", "name": "ARHGEF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MB21", "map_id": "F1MB21", "name": "ARHGEF40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017829", "map_id": "ENSBTAT00000017829", "name": "ARHGEF40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089952", "map_id": "none", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089949", "map_id": "none", "name": "RHOC GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BM23", "map_id": "E1BM23", "name": "ARHGAP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038690", "map_id": "ENSBTAT00000038690", "name": "ARHGAP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092392", "map_id": "none", "name": "RAC3 binds ER effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10092388", "map_id": "none", "name": "RAC3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A5PK69", "map_id": "A5PK69", "name": "RAC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079280", "map_id": "ENSBTAT00000079280", "name": "RAC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092384", "map_id": "none", "name": "RAC3 endoplasmic reticulum effectors", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10092390", "map_id": "none", "name": "RAC3:GTP:RAC3 endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10090330", "map_id": "none", "name": "RAC3 GEFs activate RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090323", "map_id": "none", "name": "RAC3:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090325", "map_id": "none", "name": "RAC3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090327", "map_id": "none", "name": "RAC3 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MLS2", "map_id": "F1MLS2", "name": "TRIO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061086", "map_id": "ENSBTAT00000061086", "name": "TRIO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092394", "map_id": "none", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10090349", "map_id": "none", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090341", "map_id": "none", "name": "RAC3 GDIs", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090347", "map_id": "none", "name": "RAC3:GDP:RAC3 GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090339", "map_id": "none", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090336", "map_id": "none", "name": "RAC3 GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N6V1", "map_id": "F1N6V1", "name": "ARHGAP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003400", "map_id": "ENSBTAT00000003400", "name": "ARHGAP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IF90", "map_id": "A4IF90", "name": "ARHGAP15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061453", "map_id": "ENSBTAT00000061453", "name": "ARHGAP15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089930", "map_id": "none", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089926", "map_id": "none", "name": "RHOA plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MFP5", "map_id": "A0A3Q1MFP5", "name": "PLD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068010", "map_id": "ENSBTAT00000068010", "name": "PLD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJH7", "map_id": "A0A3Q1LJH7", "name": "RHPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073587", "map_id": "ENSBTAT00000073587", "name": "RHPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X696", "map_id": "G3X696", "name": "SLK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001346", "map_id": "ENSBTAT00000001346", "name": "SLK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBT6", "map_id": "F1MBT6", "name": "ANLN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046371", "map_id": "ENSBTAT00000046371", "name": "ANLN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089928", "map_id": "none", "name": "RHOA:GTP:cytosolic RHOA effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089149", "map_id": "none", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089146", "map_id": "none", "name": "RHOA GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DB1", "map_id": "Q08DB1", "name": "TAGAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039899", "map_id": "ENSBTAT00000039899", "name": "TAGAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGB9", "map_id": "F1MGB9", "name": "ARHGAP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052139", "map_id": "ENSBTAT00000052139", "name": "ARHGAP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2Q1", "map_id": "A0A3Q1M2Q1", "name": "ARHGAP20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076617", "map_id": "ENSBTAT00000076617", "name": "ARHGAP20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BI70", "map_id": "E1BI70", "name": "ARHGAP45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027682", "map_id": "ENSBTAT00000027682", "name": "ARHGAP45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYQ4", "map_id": "F1MYQ4", "name": "ARHGAP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011665", "map_id": "ENSBTAT00000011665", "name": "ARHGAP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXE8", "map_id": "G3MXE8", "name": "MYO9A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066138", "map_id": "ENSBTAT00000066138", "name": "MYO9A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIM3", "map_id": "E1BIM3", "name": "ARHGAP11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035838", "map_id": "ENSBTAT00000035838", "name": "ARHGAP11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FV18", "map_id": "A4FV18", "name": "GMIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020147", "map_id": "ENSBTAT00000020147", "name": "GMIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LGT5", "map_id": "A0A3Q1LGT5", "name": "ARHGAP28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075956", "map_id": "ENSBTAT00000075956", "name": "ARHGAP28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089888", "map_id": "none", "name": "RHOA binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10089862", "map_id": "none", "name": "RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10089884", "map_id": "none", "name": "RHOA endoplasmic reticulum effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10089886", "map_id": "none", "name": "RHOA:GTP:RHOA endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10089011", "map_id": "none", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089008", "map_id": "none", "name": "RHOA GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BH51", "map_id": "E1BH51", "name": "PLEKHG6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005514", "map_id": "ENSBTAT00000005514", "name": "PLEKHG6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BQ24", "map_id": "E1BQ24", "name": "ARHGEF19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007450", "map_id": "ENSBTAT00000007450", "name": "ARHGEF19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8D9", "map_id": "A0A3Q1M8D9", "name": "ARHGEF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071999", "map_id": "ENSBTAT00000071999", "name": "ARHGEF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDY4", "map_id": "E1BDY4", "name": "ARHGEF15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082024", "map_id": "ENSBTAT00000082024", "name": "ARHGEF15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJS1", "map_id": "A0A3Q1LJS1", "name": "ECT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068893", "map_id": "ENSBTAT00000068893", "name": "ECT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N5A2", "map_id": "A0A3Q1N5A2", "name": "NET1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067575", "map_id": "ENSBTAT00000067575", "name": "NET1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MA88", "map_id": "A0A3Q1MA88", "name": "ARHGEF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069507", "map_id": "ENSBTAT00000069507", "name": "ARHGEF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MD11", "map_id": "A0A3Q1MD11", "name": "RASGRF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081804", "map_id": "ENSBTAT00000081804", "name": "RASGRF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089890", "map_id": "none", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10089860", "map_id": "none", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089854", "map_id": "A0A452DIS6", "name": "ARHGDIB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000007933", "map_id": "ENSBTAT00000007933", "name": "ARHGDIB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089858", "map_id": "none", "name": "RHOA GDIs:RHOA:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIS6", "map_id": "A0A452DIS6", "name": "ARHGDIB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090125", "map_id": "none", "name": "GDIs block activation of RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090093", "map_id": "none", "name": "RHOG:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q1RMI2", "map_id": "Q1RMI2", "name": "RHOG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000453", "map_id": "ENSBTAT00000000453", "name": "RHOG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090123", "map_id": "none", "name": "RHOG GDIs:RHOG:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090145", "map_id": "none", "name": "RHOG binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10090117", "map_id": "none", "name": "RHOG:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10090141", "map_id": "none", "name": "RHOG endoplasmic reticulum effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10090143", "map_id": "none", "name": "RHOG:GTP:RHOG endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10090115", "map_id": "none", "name": "RHOG binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090111", "map_id": "none", "name": "RHOG plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LX25", "map_id": "A0A3Q1LX25", "name": "PLEKHG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069555", "map_id": "ENSBTAT00000069555", "name": "PLEKHG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWX5", "map_id": "A0A3Q1LWX5", "name": "DOCK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081739", "map_id": "ENSBTAT00000081739", "name": "DOCK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT94", "map_id": "A0A3Q1MT94", "name": "DOCK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085032", "map_id": "ENSBTAT00000085032", "name": "DOCK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTR1", "map_id": "F1MTR1", "name": "IQGAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001190", "map_id": "ENSBTAT00000001190", "name": "IQGAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NNR4", "map_id": "A0A3Q1NNR4", "name": "DOCK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083570", "map_id": "ENSBTAT00000083570", "name": "DOCK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037305", "map_id": "none", "name": "RHOG:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090113", "map_id": "none", "name": "RHOG:GTP:RHOG plasma membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090098", "map_id": "none", "name": "RHOG GEFs activate RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090095", "map_id": "none", "name": "RHOG GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090103", "map_id": "none", "name": "RHOG GAPs stimulate RHOG GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090100", "map_id": "none", "name": "RHOG GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090119", "map_id": "none", "name": "RHOG translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10090089", "map_id": "none", "name": "RAC2 translocates to the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037299", "map_id": "none", "name": "RAC2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9TU25", "map_id": "Q9TU25", "name": "RAC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014666", "map_id": "ENSBTAT00000014666", "name": "RAC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073712", "map_id": "none", "name": "RAC2:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10090091", "map_id": "none", "name": "RAC2 binds effectors at the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_10073714", "map_id": "none", "name": "NOX2 complex:RAC2:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10090077", "map_id": "none", "name": "RAC2 binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090073", "map_id": "none", "name": "RAC2 plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MFB9", "map_id": "A0A3Q1MFB9", "name": "PLD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080368", "map_id": "ENSBTAT00000080368", "name": "PLD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090075", "map_id": "none", "name": "RAC2:GTP:RAC2 cytosolic effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092380", "map_id": "none", "name": "RAC2 binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10092374", "map_id": "none", "name": "RAC2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10092376", "map_id": "none", "name": "RAC2 endoplasmic reticulum effectors", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10092378", "map_id": "none", "name": "RAC2:GTP:RAC2 endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10092382", "map_id": "none", "name": "RAC2 translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10090082", "map_id": "none", "name": "RAC2 GAPs stimulate RAC2 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090033", "map_id": "none", "name": "RAC2:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090079", "map_id": "none", "name": "RAC2 GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10092370", "map_id": "none", "name": "RAC2 translocates to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092368", "map_id": "none", "name": "RAC2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10090087", "map_id": "none", "name": "RAC2 GEFs activate RAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090084", "map_id": "none", "name": "RAC2 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4M7", "map_id": "A0A3Q1M4M7", "name": "BCR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071096", "map_id": "ENSBTAT00000071096", "name": "BCR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKN5", "map_id": "A0A3Q1MKN5", "name": "DEF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080659", "map_id": "ENSBTAT00000080659", "name": "DEF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090203", "map_id": "none", "name": "RHOJ GEFs activate RHOJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090193", "map_id": "none", "name": "RHOJ:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4FV20", "map_id": "A4FV20", "name": "RHOJ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022858", "map_id": "ENSBTAT00000022858", "name": "RHOJ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090191", "map_id": "none", "name": "RHOJ:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090200", "map_id": "none", "name": "RHOJ GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BNA6", "map_id": "E1BNA6", "name": "DOCK8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002840", "map_id": "ENSBTAT00000002840", "name": "DOCK8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090198", "map_id": "none", "name": "RHOJ GAPs stimulate RHOJ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090195", "map_id": "none", "name": "RHOJ GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091994", "map_id": "none", "name": "RND2 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091990", "map_id": "none", "name": "RND2 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BLB2", "map_id": "E1BLB2", "name": "TNFAIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010671", "map_id": "ENSBTAT00000010671", "name": "TNFAIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPM3", "map_id": "A0A3Q1LPM3", "name": "FNBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068488", "map_id": "ENSBTAT00000068488", "name": "FNBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4C5", "map_id": "F1N4C5", "name": "PLXND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002375", "map_id": "ENSBTAT00000002375", "name": "PLXND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6F8", "map_id": "A0A3Q1M6F8", "name": "UBXN11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077393", "map_id": "ENSBTAT00000077393", "name": "UBXN11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091948", "map_id": "none", "name": "RND2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MUP6", "map_id": "F1MUP6", "name": "RND2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009719", "map_id": "ENSBTAT00000009719", "name": "RND2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091992", "map_id": "none", "name": "RND2:GTP:RND2 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092022", "map_id": "none", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091946", "map_id": "F1MUP6", "name": "RND2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10091832", "map_id": "none", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091827", "map_id": "none", "name": "RHOF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3SZA1", "map_id": "Q3SZA1", "name": "RHOF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046161", "map_id": "ENSBTAT00000046161", "name": "RHOF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091829", "map_id": "none", "name": "RHOF:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091864", "map_id": "none", "name": "RHOF binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091860", "map_id": "none", "name": "RHOF effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIN5", "map_id": "A0A452DIN5", "name": "BAIAP2L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020331", "map_id": "ENSBTAT00000020331", "name": "BAIAP2L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXR0", "map_id": "F1MXR0", "name": "BAIAP2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030984", "map_id": "ENSBTAT00000030984", "name": "BAIAP2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFC6", "map_id": "F1MFC6", "name": "FARP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072393", "map_id": "ENSBTAT00000072393", "name": "FARP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091862", "map_id": "none", "name": "RHOF:GTP:RHOF effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091921", "map_id": "none", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091918", "map_id": "none", "name": "RHOF GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090266", "map_id": "none", "name": "RHOQ binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090262", "map_id": "none", "name": "RHOQ effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MPX4", "map_id": "A0A3Q1MPX4", "name": "CDC42EP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082212", "map_id": "ENSBTAT00000082212", "name": "CDC42EP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MS60", "map_id": "F1MS60", "name": "ARHGAP33", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012813", "map_id": "ENSBTAT00000012813", "name": "ARHGAP33", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI46", "map_id": "Q2KI46", "name": "CDC42EP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032505", "map_id": "ENSBTAT00000032505", "name": "CDC42EP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDU0", "map_id": "A2VDU0", "name": "TRIP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018391", "map_id": "ENSBTAT00000018391", "name": "TRIP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090239", "map_id": "none", "name": "RHOQ:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MK42", "map_id": "F1MK42", "name": "RHOQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018269", "map_id": "ENSBTAT00000018269", "name": "RHOQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090264", "map_id": "none", "name": "RHOQ:GTP:RHOQ effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090369", "map_id": "none", "name": "RHOQ translocates to the Golgi-associated vesicle membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090367", "map_id": "none", "name": "RHOQ:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "reaction_10090246", "map_id": "none", "name": "RHOQ GAPs stimulate RHOQ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090241", "map_id": "none", "name": "RHOQ:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090243", "map_id": "none", "name": "RHOQ GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10092002", "map_id": "none", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091998", "map_id": "A5PKJ7", "name": "RND3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000045869", "map_id": "ENSBTAT00000045869", "name": "RND3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092000", "map_id": "none", "name": "RND3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5PKJ7", "map_id": "A5PKJ7", "name": "RND3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092020", "map_id": "none", "name": "RND3 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092016", "map_id": "none", "name": "RND3 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10092018", "map_id": "none", "name": "RND3:GTP:RND3 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10063353", "map_id": "none", "name": "PAK1 phosphorylates LIMK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047757", "map_id": "E1BC64", "name": "LIMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000061497", "map_id": "ENSBTAT00000061497", "name": "phospho-LIMK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047760", "map_id": "E1BC64", "name": "phospho-LIMK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047644", "map_id": "Q08E52", "name": "phospho-PAK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10073755", "map_id": "none", "name": "NOX3 complex:RAC1:GTP generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_352327", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_3299686", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10073752", "map_id": "none", "name": "NOX3 complex:RAC1:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BFF3", "map_id": "E1BFF3", "name": "NOX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018021", "map_id": "ENSBTAT00000018021", "name": "NOX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091180", "map_id": "none", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091177", "map_id": "none", "name": "NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091162", "map_id": "none", "name": "p-S-345-NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10040565", "map_id": "none", "name": "p-p38 MAPK alpha/beta", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091169", "map_id": "none", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091164", "map_id": "Q5BIN5", "name": "PIN1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022592", "map_id": "ENSBTAT00000022592", "name": "PIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091166", "map_id": "none", "name": "PIN1:p-S-345-NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q5BIN5", "map_id": "Q5BIN5", "name": "PIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073731", "map_id": "none", "name": "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263698", "compartment_display": "phagolysosome" }, { "id": "species_10073729", "map_id": "none", "name": "NOX2 complex:S100A8:S100A9:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "P28782", "map_id": "P28782", "name": "S100A8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066555", "map_id": "ENSBTAT00000066555", "name": "S100A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1629751", "map_id": "CHEBI:17283", "name": "PI3P", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10073716", "map_id": "none", "name": "RAC2:GTP binds NOX2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "reaction_10091175", "map_id": "none", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091173", "map_id": "none", "name": "PIN1:p-S-6S-NCF1:NCF2:NCF4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10070605", "map_id": "none", "name": "p-PKCA,p-PKCB,p-PKCZ,p-PKCD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MSP9", "map_id": "A0A3Q1MSP9", "name": "phospho-PRKCZ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070692", "map_id": "ENSBTAT00000070692", "name": "phospho-PRKCZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063374", "map_id": "none", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043441", "map_id": "none", "name": "G-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10063372", "map_id": "none", "name": "Mother filament:ARP2/3:actin:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M5Y2", "map_id": "A0A3Q1M5Y2", "name": "ACTR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084883", "map_id": "ENSBTAT00000084883", "name": "ACTR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148J6", "map_id": "Q148J6", "name": "ARPC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070990", "map_id": "ENSBTAT00000070990", "name": "ARPC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHR7", "map_id": "Q3MHR7", "name": "ARPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070600", "map_id": "ENSBTAT00000070600", "name": "ARPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXC8", "map_id": "G3MXC8", "name": "ARPC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064442", "map_id": "ENSBTAT00000064442", "name": "ARPC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NMB5", "map_id": "A0A3Q1NMB5", "name": "ARPC1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082840", "map_id": "ENSBTAT00000082840", "name": "ARPC1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58CQ2", "map_id": "Q58CQ2", "name": "ARPC1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064158", "map_id": "ENSBTAT00000064158", "name": "ARPC1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10061166", "map_id": "none", "name": "Mother filament:branching complex:daughter filament", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073577", "map_id": "none", "name": "RHOA:GTP binds RHPN1 or RHPN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073573", "map_id": "A0A3Q1LJH7", "name": "RHPN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10073575", "map_id": "none", "name": "RHOA:GTP:RHPN1,RHPN2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072515", "map_id": "none", "name": "Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072511", "map_id": "none", "name": "KTN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10072505", "map_id": "none", "name": "RHOA,RHOG,RAC1,CDC42:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10072513", "map_id": "none", "name": "RHOA,RHOG,RAC1,CDC42:GTP:KTN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10073842", "map_id": "none", "name": "KTN1 binds Kinesin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055513", "map_id": "none", "name": "Kinesin-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DH4", "map_id": "Q08DH4", "name": "KLC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025752", "map_id": "ENSBTAT00000025752", "name": "KLC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7H2", "map_id": "A6H7H2", "name": "KLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023001", "map_id": "ENSBTAT00000023001", "name": "KLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MWH8", "map_id": "A0A3Q1MWH8", "name": "KIF5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071358", "map_id": "ENSBTAT00000071358", "name": "KIF5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073840", "map_id": "none", "name": "RHOA,RHOG,RAC1,CDC42:GTP:KTN1:Kinesin-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10073806", "map_id": "none", "name": "CIT-3 binds DLG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073802", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:CIT-3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10050472", "map_id": "F1MM66", "name": "DLG4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10073804", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073796", "map_id": "none", "name": "Activated CIT binds KIF14 and PRC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073792", "map_id": "Q2T9P1", "name": "PRC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000076885", "map_id": "ENSBTAT00000076885", "name": "PRC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073788", "map_id": "G5E5S3", "name": "KIF14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000029161", "map_id": "ENSBTAT00000029161", "name": "KIF14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073784", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:CIT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073794", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E5S3", "map_id": "G5E5S3", "name": "KIF14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2T9P1", "map_id": "Q2T9P1", "name": "PRC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073561", "map_id": "none", "name": "Profilin:G-actin binds MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073541", "map_id": "A0A3Q1LLJ2", "name": "MRTFA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070929", "map_id": "ENSBTAT00000070929", "name": "MRTFA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043459", "map_id": "none", "name": "Profilin:G-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073543", "map_id": "none", "name": "Profilin:G-actin:MKL1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LLJ2", "map_id": "A0A3Q1LLJ2", "name": "MRTFA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073503", "map_id": "none", "name": "FMNL3 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073499", "map_id": "none", "name": "FMNL3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B718", "map_id": "E1B718", "name": "FMNL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022075", "map_id": "ENSBTAT00000022075", "name": "FMNL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073501", "map_id": "none", "name": "RHOC:GTP:FMNL3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073525", "map_id": "none", "name": "SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073521", "map_id": "A0A3Q1LMM5", "name": "SRGAP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000068363", "map_id": "ENSBTAT00000068363", "name": "SRGAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073517", "map_id": "none", "name": "RAC1:GTP:FMNL1:Profilin:G-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M6W5", "map_id": "A0A3Q1M6W5", "name": "FMNL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078036", "map_id": "ENSBTAT00000078036", "name": "FMNL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073523", "map_id": "none", "name": "SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LMM5", "map_id": "A0A3Q1LMM5", "name": "SRGAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073493", "map_id": "none", "name": "FMNL2 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073489", "map_id": "none", "name": "FMNL2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073491", "map_id": "none", "name": "RHOC:GTP:FMNL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073557", "map_id": "none", "name": "MKL1 binds SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068967", "map_id": "A0A3Q1LLJ2", "name": "MRTFA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10073553", "map_id": "E1BJP4", "name": "SRF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000016981", "map_id": "ENSBTAT00000016981", "name": "SRF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073555", "map_id": "none", "name": "SRF:MKL1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BJP4", "map_id": "E1BJP4", "name": "SRF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073559", "map_id": "none", "name": "MKL1 translocates from cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073547", "map_id": "none", "name": "RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073539", "map_id": "none", "name": "EVL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MSR1", "map_id": "A0A3Q1MSR1", "name": "EVL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069763", "map_id": "ENSBTAT00000069763", "name": "EVL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073545", "map_id": "none", "name": "RHOA:GTP:DIAPH1:EVL:Profilin:G-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10068939", "map_id": "none", "name": "DAAM1 recruits GTP-bound RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068935", "map_id": "none", "name": "RHOA:GTP:Mg2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068931", "map_id": "none", "name": "ppDVL:DAAM1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068937", "map_id": "none", "name": "ppDVL:DAAM1:RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073549", "map_id": "none", "name": "DIAPH1 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073535", "map_id": "none", "name": "DIAPH1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073569", "map_id": "none", "name": "SCAI binds SRF:MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073565", "map_id": "A0A3Q1M5I0", "name": "SCAI", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000072829", "map_id": "ENSBTAT00000072829", "name": "SCAI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073567", "map_id": "none", "name": "SRF:MKL1:SCAI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M5I0", "map_id": "A0A3Q1M5I0", "name": "SCAI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073507", "map_id": "none", "name": "Activated FMNL3 binds G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073505", "map_id": "none", "name": "RHOC:GTP:FMNL3:G-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043461", "map_id": "none", "name": "Association of profilin with monomeric actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043457", "map_id": "none", "name": "PFN", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10068933", "map_id": "none", "name": "ppDVL binds DAAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068929", "map_id": "none", "name": "pp-DVL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068927", "map_id": "A0A3Q1LHF1", "name": "DAAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10092203", "map_id": "none", "name": "RHOBTB3 binds interacting proteins at trans-Golgi network", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10092199", "map_id": "none", "name": "RHOBTB3 interacting proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DW1", "map_id": "Q08DW1", "name": "RAB9A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014511", "map_id": "ENSBTAT00000014511", "name": "RAB9A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX32", "map_id": "Q3SX32", "name": "PLIN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015669", "map_id": "ENSBTAT00000015669", "name": "PLIN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCB4", "map_id": "Q0VCB4", "name": "RAB9B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026403", "map_id": "ENSBTAT00000026403", "name": "RAB9B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2Y1", "map_id": "G3N2Y1", "name": "LRRC41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064452", "map_id": "ENSBTAT00000064452", "name": "LRRC41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BL53", "map_id": "E1BL53", "name": "VHL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030804", "map_id": "ENSBTAT00000030804", "name": "VHL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083329", "map_id": "none", "name": "RHOBTB3:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "A0A3Q1M2K6", "map_id": "A0A3Q1M2K6", "name": "RHOBTB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080085", "map_id": "ENSBTAT00000080085", "name": "RHOBTB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092201", "map_id": "none", "name": "RHOBTB3:ATP:RHOBTB3 interacting proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10092205", "map_id": "none", "name": "RHOBTB3 binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10083327", "map_id": "A0A3Q1M2K6", "name": "RHOBTB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "reaction_10092208", "map_id": "none", "name": "RHOBTB3 hydrolyzes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10083335", "map_id": "none", "name": "RHOBTB3:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10071262", "map_id": "none", "name": "ATP1B4 binds SNW1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10044442", "map_id": "Q1JQE0", "name": "SNW1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071258", "map_id": "A7MB71", "name": "ATP1B4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "ENSBTAT00000011740", "map_id": "ENSBTAT00000011740", "name": "ATP1B4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071260", "map_id": "none", "name": "ATP1B4:SNW1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A7MB71", "map_id": "A7MB71", "name": "ATP1B4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064933", "map_id": "none", "name": "Degradation of ubiquitinated SKI/SKIL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10064931", "map_id": "none", "name": "Ub-SKI/Ub-SKIL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N727", "map_id": "F1N727", "name": "SKI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060953", "map_id": "ENSBTAT00000060953", "name": "SKI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJ37", "map_id": "E1BJ37", "name": "SKIL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005438", "map_id": "ENSBTAT00000005438", "name": "SKIL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043311", "map_id": "none", "name": "Formation of a heteromeric BMP receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042988", "map_id": "none", "name": "BMPRI dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LSA1", "map_id": "A0A3Q1LSA1", "name": "BMPR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078787", "map_id": "ENSBTAT00000078787", "name": "BMPR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCE7", "map_id": "F1MCE7", "name": "BMPR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000282", "map_id": "ENSBTAT00000000282", "name": "BMPR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043000", "map_id": "none", "name": "BMPRII dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MGJ6", "map_id": "A0A3Q1MGJ6", "name": "ACVR2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077971", "map_id": "ENSBTAT00000077971", "name": "ACVR2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LP90", "map_id": "A0A3Q1LP90", "name": "BMPR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073964", "map_id": "ENSBTAT00000073964", "name": "BMPR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043002", "map_id": "none", "name": "BMPRII:BMPRI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084542", "map_id": "none", "name": "AMHR2 binds AMH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10084532", "map_id": "none", "name": "AMH dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MZL1", "map_id": "F1MZL1", "name": "AMH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019912", "map_id": "ENSBTAT00000019912", "name": "AMH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084538", "map_id": "none", "name": "AMHR2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BHR7", "map_id": "E1BHR7", "name": "AMHR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024657", "map_id": "ENSBTAT00000024657", "name": "AMHR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084540", "map_id": "none", "name": "AMH dimer:AMHR2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10042976", "map_id": "none", "name": "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10042969", "map_id": "A0A3Q1M3K3", "name": "SMAD5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072746", "map_id": "ENSBTAT00000072746", "name": "SMAD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056354", "map_id": "none", "name": "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056341", "map_id": "none", "name": "Activin A,AB,B:ACVR2A,B:ACVR1B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P07995", "map_id": "P07995", "name": "INHBA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066382", "map_id": "ENSBTAT00000066382", "name": "INHBA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSQ2", "map_id": "F1MSQ2", "name": "ACVR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046665", "map_id": "ENSBTAT00000046665", "name": "ACVR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056351", "map_id": "none", "name": "Activin A,AB,B:ACVR2A,B:p-ACVR1B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056356", "map_id": "none", "name": "Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056339", "map_id": "F1MSQ2", "name": "ACVR1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10042992", "map_id": "A0A3Q1MGJ6", "name": "ACVR2B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10045724", "map_id": "none", "name": "INHBA dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10068704", "map_id": "none", "name": "Phosphorylated DVL recruits PIP5K1B to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060420", "map_id": "F1N7M1", "name": "PIP5K1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000080996", "map_id": "ENSBTAT00000080996", "name": "PIP5K1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043116", "map_id": "none", "name": "pp-DVL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068702", "map_id": "none", "name": "ppDVL:PIP5K1B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N7M1", "map_id": "F1N7M1", "name": "PIP5K1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068707", "map_id": "none", "name": "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_392417", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10067694", "map_id": "none", "name": "XIAP monoubiquinates TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10067672", "map_id": "none", "name": "TLE:XIAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LJY1", "map_id": "A0A3Q1LJY1", "name": "TLE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079758", "map_id": "ENSBTAT00000079758", "name": "TLE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTE2", "map_id": "A0A3Q1LTE2", "name": "TLE4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069289", "map_id": "ENSBTAT00000069289", "name": "TLE4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3K5", "map_id": "A0A3Q1M3K5", "name": "TLE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073140", "map_id": "ENSBTAT00000073140", "name": "TLE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWG5", "map_id": "G3MWG5", "name": "XIAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067597", "map_id": "ENSBTAT00000067597", "name": "XIAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067691", "map_id": "none", "name": "ub-TLE:XIAP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10067696", "map_id": "none", "name": "XIAP binds TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10067670", "map_id": "G3MWG5", "name": "XIAP", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10067668", "map_id": "none", "name": "TLE tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10067698", "map_id": "none", "name": "XIAP dissociates from ub-TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10067689", "map_id": "none", "name": "ub-TLE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10068095", "map_id": "none", "name": "USP34 deubiquitinates AXIN1,AXIN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068083", "map_id": "none", "name": "Ub-RibC-AXIN:TNKS:RNF146", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M230", "map_id": "A0A3Q1M230", "name": "TNKS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085809", "map_id": "ENSBTAT00000085809", "name": "TNKS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8R5", "map_id": "E1B8R5", "name": "TNKS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001917", "map_id": "ENSBTAT00000001917", "name": "TNKS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T139", "map_id": "Q3T139", "name": "RNF146B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038099", "map_id": "ENSBTAT00000038099", "name": "RNF146B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068071", "map_id": "none", "name": "RibC-AXIN:TNKS:RNF146", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068092", "map_id": "A0A3Q1MDV7", "name": "USP34", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000078346", "map_id": "ENSBTAT00000078346", "name": "USP34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068073", "map_id": "none", "name": "RNF146 binds RibC-AXIN:TNKS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068054", "map_id": "Q3T139", "name": "RNF146B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10068069", "map_id": "none", "name": "RibC-AXIN:TNKS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068088", "map_id": "none", "name": "Tankyrase binds AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041524", "map_id": "M5FK80", "name": "AXIN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10068067", "map_id": "none", "name": "TNKS1/2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068075", "map_id": "none", "name": "AXIN:TNKS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068078", "map_id": "none", "name": "Tankyrase ADP-ribosylates AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197277", "map_id": "CHEBI:17154", "name": "NAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10068086", "map_id": "none", "name": "RNF146 ubiquitinates ADP-ribosylated AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10067879", "map_id": "none", "name": "SET1 complex trimethylates H3K4 at the MYC gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_77087", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10067848", "map_id": "none", "name": "MYC gene: H2B K121ub nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P62803", "map_id": "P62803", "name": "Histone H4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072717", "map_id": "ENSBTAT00000072717", "name": "Histone H4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMV7", "map_id": "A0A3Q1LMV7", "name": "LOC107131556", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085055", "map_id": "ENSBTAT00000085055", "name": "LOC107131556", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_77502", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10067852", "map_id": "none", "name": "MYC gene:H2B K121ub H3K4me3 nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10067876", "map_id": "none", "name": "TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MHP8", "map_id": "F1MHP8", "name": "PYGO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012057", "map_id": "ENSBTAT00000012057", "name": "PYGO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEP4", "map_id": "E1BEP4", "name": "ASH2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001294", "map_id": "ENSBTAT00000001294", "name": "ASH2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MZ99", "map_id": "A0A3Q1MZ99", "name": "LEF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068676", "map_id": "ENSBTAT00000068676", "name": "LEF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAN6", "map_id": "A0A3Q1MAN6", "name": "TCF7L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079320", "map_id": "ENSBTAT00000079320", "name": "TCF7L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FUE3", "map_id": "A4FUE3", "name": "RBBP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021204", "map_id": "ENSBTAT00000021204", "name": "RBBP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPF3", "map_id": "E1BPF3", "name": "BCL9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080372", "map_id": "ENSBTAT00000080372", "name": "BCL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6V2", "map_id": "A0A3Q1M6V2", "name": "BCL9L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067448", "map_id": "ENSBTAT00000067448", "name": "BCL9L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N7T9", "map_id": "A0A3Q1N7T9", "name": "KMT2D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083957", "map_id": "ENSBTAT00000083957", "name": "KMT2D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071330", "map_id": "none", "name": "Canonical WNT signaling through the atypical receptor RYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10071326", "map_id": "none", "name": "RYK-binding WNTs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1N5R1", "map_id": "F1N5R1", "name": "WNT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021312", "map_id": "ENSBTAT00000021312", "name": "WNT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071324", "map_id": "A0A3Q1N0Q2", "name": "RYK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071795", "map_id": "ENSBTAT00000071795", "name": "RYK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071328", "map_id": "none", "name": "RYK:WNTs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N0Q2", "map_id": "A0A3Q1N0Q2", "name": "RYK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069645", "map_id": "none", "name": "RSPO:LGR binds ZNRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069631", "map_id": "none", "name": "RSPO:LGR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MH47", "map_id": "F1MH47", "name": "RSPO4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029170", "map_id": "ENSBTAT00000029170", "name": "RSPO4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ME23", "map_id": "F1ME23", "name": "RSPO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078037", "map_id": "ENSBTAT00000078037", "name": "RSPO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RLD1", "map_id": "F6RLD1", "name": "RSPO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018083", "map_id": "ENSBTAT00000018083", "name": "RSPO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIK6", "map_id": "A0A452DIK6", "name": "LGR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017631", "map_id": "ENSBTAT00000017631", "name": "LGR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLJ7", "map_id": "F1MLJ7", "name": "SLIT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061059", "map_id": "ENSBTAT00000061059", "name": "SLIT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069641", "map_id": "none", "name": "ZNRF3,RNF43", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MCX1", "map_id": "A0A3Q1MCX1", "name": "ZNRF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083590", "map_id": "ENSBTAT00000083590", "name": "ZNRF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNT4", "map_id": "E1BNT4", "name": "RNF43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026797", "map_id": "ENSBTAT00000026797", "name": "RNF43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069643", "map_id": "none", "name": "RSPO:LGR:ZNRF3,RNF43", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069647", "map_id": "none", "name": "RSPOs bind LGRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069615", "map_id": "none", "name": "LGR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069629", "map_id": "none", "name": "RSPO", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10069664", "map_id": "none", "name": "ZNRF3 autoubiquitinates to promote its internalization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069661", "map_id": "none", "name": "RSPO:LGR:ub-ZNRF3,RNF43", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069607", "map_id": "none", "name": "DACT1 binds DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069603", "map_id": "F1MP88", "name": "DACT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025871", "map_id": "ENSBTAT00000025871", "name": "DACT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043149", "map_id": "A0A3Q1MSZ4", "name": "DVL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069605", "map_id": "none", "name": "DVL2:DACT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MP88", "map_id": "F1MP88", "name": "DACT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068923", "map_id": "none", "name": "DVL is recruited to the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10068919", "map_id": "none", "name": "p-DVL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068917", "map_id": "none", "name": "WNT:FZD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N4K7", "map_id": "F1N4K7", "name": "FZD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002946", "map_id": "ENSBTAT00000002946", "name": "FZD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4C0", "map_id": "F1N4C0", "name": "WNT11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014355", "map_id": "ENSBTAT00000014355", "name": "WNT11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068921", "map_id": "none", "name": "WNT:FZD:pDVL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069896", "map_id": "none", "name": "WNT5A binds FZD and ROR receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069892", "map_id": "none", "name": "FZD2/FZD5/ROR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BC57", "map_id": "E1BC57", "name": "ROR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061589", "map_id": "ENSBTAT00000061589", "name": "ROR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069894", "map_id": "none", "name": "WNT5A:FZDs/ROR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069882", "map_id": "none", "name": "WNT5A-FZD4 recruits DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069874", "map_id": "none", "name": "N4GlycoAsn-PalmS-WNT5A:FZD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MLJ8", "map_id": "F1MLJ8", "name": "FZD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061370", "map_id": "ENSBTAT00000061370", "name": "FZD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069878", "map_id": "none", "name": "WNT5A:FZD4:DVL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069876", "map_id": "none", "name": "WNT5A binds FZD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069862", "map_id": "F1MLJ8", "name": "FZD4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10069299", "map_id": "none", "name": "DAAM1 recruits PFN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043451", "map_id": "none", "name": "Homologues of PFN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P02584", "map_id": "P02584", "name": "PFN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024367", "map_id": "ENSBTAT00000024367", "name": "PFN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHJ0", "map_id": "E1BHJ0", "name": "PFN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069297", "map_id": "none", "name": "ppDVL:DAAM1:PFN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10069448", "map_id": "none", "name": "Dissociation of CaM and CAMK2 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069445", "map_id": "none", "name": "p-T286 CAMK2:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10069441", "map_id": "none", "name": "p-T286,T305,T306-CAMK2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10037002", "map_id": "none", "name": "CALM1:4xCa2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10069456", "map_id": "none", "name": "Active calmodulin binds CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069452", "map_id": "none", "name": "CAMK2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10069454", "map_id": "none", "name": "CAMK2:CaM", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10069459", "map_id": "none", "name": "Autophosphorylation and activation of CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10067128", "map_id": "none", "name": "WLS binds WNT ligands in the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10067122", "map_id": "none", "name": "palmitoleyl-N-glycosylated WNTs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "A0A3Q1LVG1", "map_id": "A0A3Q1LVG1", "name": "WNT5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068978", "map_id": "ENSBTAT00000068978", "name": "WNT5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN70", "map_id": "F1MN70", "name": "WNT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018592", "map_id": "ENSBTAT00000018592", "name": "WNT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6L8", "map_id": "F1N6L8", "name": "WNT7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002188", "map_id": "ENSBTAT00000002188", "name": "WNT7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQ82", "map_id": "A0A3Q1MQ82", "name": "WNT7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083229", "map_id": "ENSBTAT00000083229", "name": "WNT7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJR6", "map_id": "A0A3Q1MJR6", "name": "WNT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085976", "map_id": "ENSBTAT00000085976", "name": "WNT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066990", "map_id": "A0A3Q1MGH5", "name": "WLS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000077814", "map_id": "ENSBTAT00000077814", "name": "WLS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067126", "map_id": "none", "name": "WLS:WNT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MGH5", "map_id": "A0A3Q1MGH5", "name": "WLS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067200", "map_id": "none", "name": "secretion of WNT ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10067168", "map_id": "none", "name": "WLS:WNT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10067198", "map_id": "none", "name": "WNTs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M1A0", "map_id": "A0A3Q1M1A0", "name": "WNT9B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086580", "map_id": "ENSBTAT00000086580", "name": "WNT9B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H6X8", "map_id": "A6H6X8", "name": "WNT2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018985", "map_id": "ENSBTAT00000018985", "name": "WNT2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPF5", "map_id": "A0A3Q1MPF5", "name": "WNT9A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081055", "map_id": "ENSBTAT00000081055", "name": "WNT9A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4D7S0", "map_id": "A4D7S0", "name": "WNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010650", "map_id": "ENSBTAT00000010650", "name": "WNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEW8", "map_id": "F1MEW8", "name": "WNT10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012148", "map_id": "ENSBTAT00000012148", "name": "WNT10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MK64", "map_id": "F1MK64", "name": "WNT10B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020402", "map_id": "ENSBTAT00000020402", "name": "WNT10B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067130", "map_id": "A0A3Q1MGH5", "name": "WLS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10067202", "map_id": "none", "name": "WNT ligands traffic to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10066994", "map_id": "none", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10066988", "map_id": "none", "name": "WLS:retromer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "Q1RMH8", "map_id": "Q1RMH8", "name": "SNX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025026", "map_id": "ENSBTAT00000025026", "name": "SNX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VD53", "map_id": "Q0VD53", "name": "VPS26A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022455", "map_id": "ENSBTAT00000022455", "name": "VPS26A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJG5", "map_id": "Q2HJG5", "name": "VPS35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003239", "map_id": "ENSBTAT00000003239", "name": "VPS35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066992", "map_id": "none", "name": "WLS:retromer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10068837", "map_id": "none", "name": "WNTs are secreted in exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_383505", "compartment_display": "extracellular exosome" }, { "id": "species_10068795", "map_id": "none", "name": "WLS:WNT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_3828050", "compartment_display": "multivesicular body, internal vesicle", "complex": "true" }, { "id": "species_10068835", "map_id": "none", "name": "WLS:WNT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_383505", "compartment_display": "extracellular exosome", "complex": "true" }, { "id": "reaction_10067124", "map_id": "none", "name": "WNT ligands traffic to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10067086", "map_id": "none", "name": "palmitoleyl-N-glycosylated WNTs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10067204", "map_id": "none", "name": "WLS is endocytosed to the early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10066982", "map_id": "A0A3Q1MGH5", "name": "WLS", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10068839", "map_id": "none", "name": "WLS:WNT complex is internalized for maturation into exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10041640", "map_id": "none", "name": "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041614", "map_id": "none", "name": "p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LMC7", "map_id": "A0A3Q1LMC7", "name": "APC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086393", "map_id": "ENSBTAT00000086393", "name": "APC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEW4", "map_id": "E1BEW4", "name": "LOC613515", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057200", "map_id": "ENSBTAT00000057200", "name": "LOC613515", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35507", "map_id": "P35507", "name": "CSNK1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030064", "map_id": "ENSBTAT00000030064", "name": "CSNK1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MI36", "map_id": "A0A3Q1MI36", "name": "CSNK1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064284", "map_id": "ENSBTAT00000064284", "name": "CSNK1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NFM1", "map_id": "A0A3Q1NFM1", "name": "LOC100138998", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052805", "map_id": "ENSBTAT00000052805", "name": "LOC100138998", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BL05", "map_id": "E1BL05", "name": "AMER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011639", "map_id": "ENSBTAT00000011639", "name": "AMER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041594", "map_id": "none", "name": "p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041629", "map_id": "none", "name": "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041610", "map_id": "none", "name": "p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041647", "map_id": "none", "name": "Phosphorylation of beta-catenin at Ser45 by CK1 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041644", "map_id": "none", "name": "CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10041634", "map_id": "none", "name": "p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041637", "map_id": "none", "name": "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10063849", "map_id": "none", "name": "Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063841", "map_id": "none", "name": "RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZCF3", "map_id": "Q3ZCF3", "name": "SKP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035306", "map_id": "ENSBTAT00000035306", "name": "SKP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNF8", "map_id": "A0A3Q1LNF8", "name": "LOC780968", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075328", "map_id": "ENSBTAT00000075328", "name": "LOC780968", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYD0", "map_id": "F1MYD0", "name": "CUL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068449", "map_id": "ENSBTAT00000068449", "name": "CUL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063845", "map_id": "none", "name": "ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10087597", "map_id": "none", "name": "TLE tetramers bind TCF/LEF at WNT promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087593", "map_id": "none", "name": "'canonical' WNT target genes:TCF/LEF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10087595", "map_id": "none", "name": "'canonical' WNT target gene:TCF/LEF:TLE tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071356", "map_id": "none", "name": "TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071346", "map_id": "none", "name": "TCF7L2/TCF7L1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10071352", "map_id": "none", "name": "CTBPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M504", "map_id": "A0A3Q1M504", "name": "CTBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066753", "map_id": "ENSBTAT00000066753", "name": "CTBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071354", "map_id": "none", "name": "TCF7L2/TCF7L1:CTBPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10069651", "map_id": "none", "name": "TLE oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069649", "map_id": "none", "name": "TLE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10041583", "map_id": "none", "name": "Assembly of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041570", "map_id": "E1BL05", "name": "AMER1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041520", "map_id": "none", "name": "Homologues of CSNK1A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10041566", "map_id": "none", "name": "PP2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041579", "map_id": "A0A3Q1LMC7", "name": "APC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041581", "map_id": "none", "name": "AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070931", "map_id": "none", "name": "AXIN is phosphorylated in the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041590", "map_id": "none", "name": "p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063843", "map_id": "none", "name": "Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043873", "map_id": "none", "name": "BTRC:CUL1:RBX1:SKP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10041599", "map_id": "none", "name": "p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041604", "map_id": "none", "name": "Phosphorylation of APC component of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041606", "map_id": "none", "name": "Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10060556", "map_id": "none", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060426", "map_id": "none", "name": "PIP5K1A-C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MBL1", "map_id": "A0A3Q1MBL1", "name": "PIP5K1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076329", "map_id": "ENSBTAT00000076329", "name": "PIP5K1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLC5", "map_id": "A6QLC5", "name": "PIP5K1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008015", "map_id": "ENSBTAT00000008015", "name": "PIP5K1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060448", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806240", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10060445", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MHR4", "map_id": "F1MHR4", "name": "PIP4K2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024007", "map_id": "ENSBTAT00000024007", "name": "PIP4K2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHT2", "map_id": "F1MHT2", "name": "PIP4K2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008517", "map_id": "ENSBTAT00000008517", "name": "PIP4K2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087531", "map_id": "none", "name": "MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087525", "map_id": "none", "name": "MECOM:PTEN gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MWB8", "map_id": "A0A3Q1MWB8", "name": "MECOM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079180", "map_id": "ENSBTAT00000079180", "name": "MECOM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087523", "map_id": "none", "name": "PRC1.4,PRC2 (EZH2) core", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10087529", "map_id": "none", "name": "MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10065099", "map_id": "none", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043178", "map_id": "F1MQJ7", "name": "PDPK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065097", "map_id": "none", "name": "PDPK1:PIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_6810412", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10065227", "map_id": "none", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10036981", "map_id": "none", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036972", "map_id": "none", "name": "p-T200-CAMK4:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M5T5", "map_id": "A0A3Q1M5T5", "name": "phospho-CAMK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086155", "map_id": "ENSBTAT00000086155", "name": "phospho-CAMK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036978", "map_id": "none", "name": "p-S12.S13,T200-CAMK4:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10049478", "map_id": "none", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049470", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BIP3", "map_id": "E1BIP3", "name": "phospho-CAMKK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009431", "map_id": "ENSBTAT00000009431", "name": "phospho-CAMKK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049475", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10037022", "map_id": "none", "name": "cAMP hydrolysis by Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037019", "map_id": "none", "name": "activated PDE1 dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MCV4", "map_id": "A0A3Q1MCV4", "name": "PDE1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066843", "map_id": "ENSBTAT00000066843", "name": "PDE1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P14100", "map_id": "P14100", "name": "PDE1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052318", "map_id": "ENSBTAT00000052318", "name": "PDE1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037024", "map_id": "none", "name": "Calmodulin activates Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10037004", "map_id": "none", "name": "Adenylate cyclase produces cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036997", "map_id": "none", "name": "Adenylate cyclase (Mg2+ cofactor)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MA58", "map_id": "A0A3Q1MA58", "name": "ADCY4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080069", "map_id": "ENSBTAT00000080069", "name": "ADCY4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9K3", "map_id": "E1B9K3", "name": "ADCY6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069484", "map_id": "ENSBTAT00000069484", "name": "ADCY6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BM79", "map_id": "E1BM79", "name": "ADCY9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073752", "map_id": "ENSBTAT00000073752", "name": "ADCY9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041863", "map_id": "none", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10041855", "map_id": "A0A3Q1MRR6", "name": "PRKCD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041860", "map_id": "A0A3Q1MRR6", "name": "phospho-PRKCD", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_112275", "map_id": "CHEBI:18035", "name": "DAGs", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10063544", "map_id": "none", "name": "Translocation of YAP1:ZO-2 (TJP2) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063538", "map_id": "none", "name": "YAP1:TJP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MK73", "map_id": "F1MK73", "name": "YAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006112", "map_id": "ENSBTAT00000006112", "name": "YAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MEH9", "map_id": "A0A3Q1MEH9", "name": "TJP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069935", "map_id": "ENSBTAT00000069935", "name": "TJP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063542", "map_id": "none", "name": "YAP1:TJP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10063550", "map_id": "none", "name": "WWTR1 (TAZ) binds ZO-1 (TJP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063333", "map_id": "A0A3Q1NBB6", "name": "WWTR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000084991", "map_id": "ENSBTAT00000084991", "name": "WWTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063546", "map_id": "F1N2D3", "name": "TJP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000038824", "map_id": "ENSBTAT00000038824", "name": "TJP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063548", "map_id": "none", "name": "WWTR1:TJP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N2D3", "map_id": "F1N2D3", "name": "TJP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NBB6", "map_id": "A0A3Q1NBB6", "name": "WWTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063408", "map_id": "none", "name": "KIBRA (WWC1) binds LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063404", "map_id": "F1N3I6", "name": "WWC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000019472", "map_id": "ENSBTAT00000019472", "name": "WWC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063259", "map_id": "none", "name": "LATS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B9F9", "map_id": "E1B9F9", "name": "phospho-LATS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019161", "map_id": "ENSBTAT00000019161", "name": "phospho-LATS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCH5", "map_id": "E1BCH5", "name": "LATS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020062", "map_id": "ENSBTAT00000020062", "name": "LATS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063406", "map_id": "none", "name": "KIBRA:LATS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N3I6", "map_id": "F1N3I6", "name": "WWC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063568", "map_id": "none", "name": "DVL2 binds phosphorylated WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063336", "map_id": "A0A3Q1NBB6", "name": "phospho-WWTR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10063566", "map_id": "none", "name": "p-WWTR1:DVL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063346", "map_id": "none", "name": "AMOT proteins bind WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063303", "map_id": "none", "name": "AMOT proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4X1", "map_id": "A0A3Q1M4X1", "name": "AMOT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077481", "map_id": "ENSBTAT00000077481", "name": "AMOT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIV8", "map_id": "A0A452DIV8", "name": "AMOTL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025212", "map_id": "ENSBTAT00000025212", "name": "AMOTL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063344", "map_id": "none", "name": "AMOT:WWTR1 (TAZ)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063317", "map_id": "none", "name": "Phosphorylation of YAP by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057276", "map_id": "F1MK73", "name": "YAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10063312", "map_id": "F1MK73", "name": "phospho-YAP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10063314", "map_id": "none", "name": "p-LATS1:p-MOB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4W1", "map_id": "A0A3Q1M4W1", "name": "phospho-MOB1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081411", "map_id": "ENSBTAT00000081411", "name": "phospho-MOB1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBK1", "map_id": "A0A3Q1MBK1", "name": "phospho-MOB1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081480", "map_id": "ENSBTAT00000081480", "name": "phospho-MOB1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063380", "map_id": "none", "name": "Translocation of WWTR1 (TAZ) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063378", "map_id": "A0A3Q1NBB6", "name": "WWTR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10063319", "map_id": "none", "name": "Phosphorylated MOB1A proteins associate with LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063273", "map_id": "none", "name": "p-MOB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10063275", "map_id": "none", "name": "LATS:p-MOB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063382", "map_id": "none", "name": "Translocation of YAP1 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057280", "map_id": "F1MK73", "name": "YAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10063305", "map_id": "none", "name": "Phosphorylation of YAP by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063290", "map_id": "F1MK73", "name": "phospho-YAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10063292", "map_id": "none", "name": "p-LATS2:p-MOB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063338", "map_id": "none", "name": "Phosphorylation of WWTR1 (TAZ) by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10063342", "map_id": "none", "name": "AMOT proteins bind YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063340", "map_id": "none", "name": "AMOT:YAP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063534", "map_id": "none", "name": "Phosphorylation of WWTR1 (TAZ) by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10063329", "map_id": "none", "name": "YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037668", "map_id": "none", "name": "YWHAB dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A140T894", "map_id": "A0A140T894", "name": "YWHAB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022411", "map_id": "ENSBTAT00000022411", "name": "YWHAB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063327", "map_id": "none", "name": "p-YAP1:YWHAB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063554", "map_id": "none", "name": "WWTR1 (TAZ) binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10063536", "map_id": "A0A3Q1MEH9", "name": "TJP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10063552", "map_id": "none", "name": "WWTR1:TJP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063556", "map_id": "none", "name": "YAP1 binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10043753", "map_id": "none", "name": "JNK phosphorylates BIM, BAD and other targets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037714", "map_id": "A0A3Q1NJ55", "name": "BCL2L11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000078264", "map_id": "ENSBTAT00000078264", "name": "phospho-BCL2L11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037676", "map_id": "F1MUT9", "name": "BAD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000016610", "map_id": "ENSBTAT00000016610", "name": "phospho-BAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043750", "map_id": "A0A3Q1NJ55", "name": "phospho-BCL2L11", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043747", "map_id": "F1MUT9", "name": "phospho-BAD", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041333", "map_id": "none", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10039497", "map_id": "A0A3Q1LWJ8", "name": "phospho-MAPK8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10043739", "map_id": "none", "name": "Polyubiquitinated NRIF migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10043729", "map_id": "none", "name": "Ubiquitinated NRIF:Sequestosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M6A8", "map_id": "A0A3Q1M6A8", "name": "ITGB3BP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083119", "map_id": "ENSBTAT00000083119", "name": "ITGB3BP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043737", "map_id": "none", "name": "Ubiquitinated NRIF:Sequestosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10043744", "map_id": "none", "name": "Polyubiquitinated NRIF binds to p62 (Sequestosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043741", "map_id": "none", "name": "Ubiquitinated NRIF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043723", "map_id": "A0A3Q1LVE4", "name": "SQSTM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10043778", "map_id": "none", "name": "TRAF6 polyubiquitinates NRIF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043719", "map_id": "none", "name": "K63 linked polyubiquitin chain", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043727", "map_id": "A0A3Q1M6A8", "name": "ITGB3BP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043761", "map_id": "none", "name": "TRAF6 homotrimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10043877", "map_id": "none", "name": "IkB is ubiquitinated and degraded", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043875", "map_id": "none", "name": "Ubiquitinated phospho-IkB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8WNW7", "map_id": "Q8WNW7", "name": "phospho-NFKBIA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041470", "map_id": "none", "name": "RhoA is activated by nucleotide exchange and inhibits axonal growth", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10041467", "map_id": "A0A3Q1MRV3", "name": "LOC112445816", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071524", "map_id": "none", "name": "BIRC(cIAP1/2) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071516", "map_id": "none", "name": "TNF-alpha:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3SYW8", "map_id": "Q3SYW8", "name": "BIRC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034719", "map_id": "ENSBTAT00000034719", "name": "BIRC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT71", "map_id": "A0A3Q1MT71", "name": "BIRC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070103", "map_id": "ENSBTAT00000070103", "name": "BIRC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZK6", "map_id": "Q3SZK6", "name": "phospho-RIPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008367", "map_id": "ENSBTAT00000008367", "name": "phospho-RIPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI74", "map_id": "Q2KI74", "name": "TRADD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016776", "map_id": "ENSBTAT00000016776", "name": "TRADD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9D9", "map_id": "E1B9D9", "name": "TRAF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013869", "map_id": "ENSBTAT00000013869", "name": "TRAF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071521", "map_id": "none", "name": "TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071556", "map_id": "none", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071552", "map_id": "none", "name": "LUBAC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BMK3", "map_id": "E1BMK3", "name": "RNF31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061147", "map_id": "ENSBTAT00000061147", "name": "RNF31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JPC8", "map_id": "Q1JPC8", "name": "RBCK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022612", "map_id": "ENSBTAT00000022612", "name": "RBCK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDF2", "map_id": "E1BDF2", "name": "SHARPIN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049670", "map_id": "ENSBTAT00000049670", "name": "SHARPIN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071554", "map_id": "none", "name": "TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071526", "map_id": "none", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036142", "map_id": "none", "name": "TNF-alpha:TNFR1:TRADD:RIPK1:TRAF2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10071514", "map_id": "none", "name": "BIRC2,3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10037964", "map_id": "none", "name": "TRADD:TRAF2:RIP1 complex binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035378", "map_id": "Q645M6", "name": "FADD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024322", "map_id": "ENSBTAT00000024322", "name": "FADD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036144", "map_id": "none", "name": "TRAF2:TRADD:RIPK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10037952", "map_id": "none", "name": "TRADD:TRAF2:RIPK1:FADD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q645M6", "map_id": "Q645M6", "name": "FADD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037962", "map_id": "none", "name": "RIPK1 deubiquitinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NKI9", "map_id": "A0A3Q1NKI9", "name": "TNFAIP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069028", "map_id": "ENSBTAT00000069028", "name": "TNFAIP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067908", "map_id": "none", "name": "TNF-alpha is cleaved by ADAM17 (TACE)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10036154", "map_id": "none", "name": "TNF(1-233) trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DJ61", "map_id": "A0A452DJ61", "name": "TNF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035815", "map_id": "ENSBTAT00000035815", "name": "TNF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067885", "map_id": "none", "name": "TNF-alpha trimer, soluble form", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10067899", "map_id": "none", "name": "TNF(1-76) trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10067905", "map_id": "none", "name": "ADAM17", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B867", "map_id": "E1B867", "name": "ADAM17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001519", "map_id": "ENSBTAT00000001519", "name": "ADAM17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092026", "map_id": "none", "name": "Caspase-8 and FLIP(L) processing at TNFR signaling complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067893", "map_id": "none", "name": "TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MLX3", "map_id": "A0A3Q1MLX3", "name": "CFLAR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085853", "map_id": "ENSBTAT00000085853", "name": "CFLAR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092024", "map_id": "none", "name": "TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10068040", "map_id": "A0A3Q1MLX3", "name": "CFLAR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10092031", "map_id": "none", "name": "RIPK1 is cleaved by CASP8:FLIP(L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092028", "map_id": "none", "name": "TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10071528", "map_id": "Q3SZK6", "name": "RIPK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071534", "map_id": "none", "name": "RIPK1 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071532", "map_id": "none", "name": "TRAF2:TRADD:RIPK1(325-671):FADD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084723", "map_id": "none", "name": "SPPL2a/b cleaves TNF(1-76)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084710", "map_id": "A0A452DJ61", "name": "TNF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10084708", "map_id": "A0A452DJ61", "name": "TNF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084720", "map_id": "none", "name": "SPPL2A,SPPL2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MBP7", "map_id": "A0A3Q1MBP7", "name": "SPPL2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077127", "map_id": "ENSBTAT00000077127", "name": "SPPL2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKF8", "map_id": "E1BKF8", "name": "SPPL2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035792", "map_id": "ENSBTAT00000035792", "name": "SPPL2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071541", "map_id": "none", "name": "RIPK1 is deubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071539", "map_id": "E1BAL0", "name": "CLIP3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026221", "map_id": "ENSBTAT00000026221", "name": "CLIP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067895", "map_id": "none", "name": "FLIP(L) and procaspase-8 form heterodimer in TNF signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067887", "map_id": "A0A3Q1MLX3", "name": "CFLAR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035384", "map_id": "Q2LGB8", "name": "CASP8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035726", "map_id": "none", "name": "FASL binds FAS Receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10033920", "map_id": "A5D7R0", "name": "FAS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014282", "map_id": "ENSBTAT00000014282", "name": "FAS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033916", "map_id": "A6H6Z6", "name": "FASLG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000046575", "map_id": "ENSBTAT00000046575", "name": "FASLG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033922", "map_id": "none", "name": "FASL:FAS Receptor monomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6H6Z6", "map_id": "A6H6Z6", "name": "FASLG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7R0", "map_id": "A5D7R0", "name": "FAS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036146", "map_id": "none", "name": "FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10035380", "map_id": "none", "name": "FASL:FAS Receptor Trimer:FADD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10035386", "map_id": "none", "name": "FASL:FAS trimer:FADD:CASP8(1-479)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10036148", "map_id": "none", "name": "FasL:Fas binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10033924", "map_id": "none", "name": "FASL:FAS Receptor Trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10033926", "map_id": "none", "name": "Trimerization of the FASL:FAS receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10045016", "map_id": "none", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10045007", "map_id": "none", "name": "RAP1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P61223", "map_id": "P61223", "name": "RAP1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019575", "map_id": "ENSBTAT00000019575", "name": "RAP1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P62833", "map_id": "P62833", "name": "RAP1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068678", "map_id": "ENSBTAT00000068678", "name": "RAP1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045005", "map_id": "none", "name": "RAP1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10045013", "map_id": "none", "name": "CalDAG-GEFs:DAG:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_6797635", "map_id": "CHEBI:17815", "name": "1,2-DAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "E1BG59", "map_id": "E1BG59", "name": "phospho-RASGRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029159", "map_id": "ENSBTAT00000029159", "name": "phospho-RASGRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053213", "map_id": "none", "name": "Activation of Rap1 by membrane-associated GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047532", "map_id": "none", "name": "Rap1 cAMP-GEFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BPX7", "map_id": "E1BPX7", "name": "RAPGEF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061074", "map_id": "ENSBTAT00000061074", "name": "RAPGEF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LHN3", "map_id": "A0A3Q1LHN3", "name": "RAPGEF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085533", "map_id": "ENSBTAT00000085533", "name": "RAPGEF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049279", "map_id": "none", "name": "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037443", "map_id": "none", "name": "Integrin alpha2bbeta3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049276", "map_id": "none", "name": "Integrin alpha IIb p(T779)-beta 3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049506", "map_id": "none", "name": "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049502", "map_id": "none", "name": "Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049504", "map_id": "none", "name": "Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071673", "map_id": "none", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975599", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_975622", "map_id": "CHEBI:17898", "name": "atRAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071670", "map_id": "none", "name": "ADH1A,1C,4 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MFZ4", "map_id": "F1MFZ4", "name": "ADH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003769", "map_id": "ENSBTAT00000003769", "name": "ADH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076840", "map_id": "none", "name": "ALDH8A1 oxidises 9cRAL to 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5362565", "map_id": "CHEBI:78273", "name": "9cRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5362520", "map_id": "CHEBI:50648", "name": "9cRA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10076837", "map_id": "A0A140T874", "name": "ALDH8A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010485", "map_id": "ENSBTAT00000010485", "name": "ALDH8A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071691", "map_id": "none", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071688", "map_id": "none", "name": "RDH11,14,DHRS3,DHRS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MZD5", "map_id": "F1MZD5", "name": "DHRS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023493", "map_id": "ENSBTAT00000023493", "name": "DHRS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BM93", "map_id": "E1BM93", "name": "RDH11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002535", "map_id": "ENSBTAT00000002535", "name": "RDH11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QW3", "map_id": "Q17QW3", "name": "RDH14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006933", "map_id": "ENSBTAT00000006933", "name": "RDH14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071659", "map_id": "none", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5334816", "map_id": "CHEBI:15367", "name": "atRA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071656", "map_id": "none", "name": "ALDH1A1,2,3 tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P48644", "map_id": "P48644", "name": "ALDH1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010661", "map_id": "ENSBTAT00000010661", "name": "ALDH1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHR3", "map_id": "F1MHR3", "name": "ALDH1A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012030", "map_id": "ENSBTAT00000012030", "name": "ALDH1A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072397", "map_id": "none", "name": "CRABP1 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071664", "map_id": "P62964", "name": "CRABP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000017158", "map_id": "ENSBTAT00000017158", "name": "CRABP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071666", "map_id": "none", "name": "SUMO-CRABP1:atRA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_215573", "map_id": "CHEBI:15367", "name": "atRA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "P62964", "map_id": "P62964", "name": "CRABP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071678", "map_id": "none", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30927", "map_id": "CHEBI:16302", "name": "11cROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_32737", "map_id": "CHEBI:16066", "name": "11cRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071675", "map_id": "none", "name": "RDH5(24-318), RDH11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q27979", "map_id": "Q27979", "name": "RDH5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065932", "map_id": "ENSBTAT00000065932", "name": "RDH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072433", "map_id": "none", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_5623644", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623648", "map_id": "CHEBI:17898", "name": "atRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_163953", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623650", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5623649", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10072430", "map_id": "Q17QC2", "name": "RDH13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000029403", "map_id": "ENSBTAT00000029403", "name": "RDH13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072225", "map_id": "none", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10071648", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071645", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q8HYR6", "map_id": "Q8HYR6", "name": "DHRS9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005986", "map_id": "ENSBTAT00000005986", "name": "DHRS9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0V8D0", "map_id": "Q0V8D0", "name": "RDH16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001829", "map_id": "ENSBTAT00000001829", "name": "RDH16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8HZT6", "map_id": "Q8HZT6", "name": "RDH10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026830", "map_id": "ENSBTAT00000026830", "name": "RDH10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044211", "map_id": "none", "name": "CYP26C1 4-hydroxylates 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5362524", "map_id": "CHEBI:63802", "name": "4OH-9cRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044208", "map_id": "E1BDT5", "name": "CYP26C1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000056396", "map_id": "ENSBTAT00000056396", "name": "CYP26C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071668", "map_id": "none", "name": "CYP26A1,B1,C1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5362521", "map_id": "CHEBI:63795", "name": "4OH-atRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044290", "map_id": "none", "name": "CYP26A1,B1,C1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MZS4", "map_id": "F1MZS4", "name": "CYP26A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028140", "map_id": "ENSBTAT00000028140", "name": "CYP26A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHJ4", "map_id": "E1BHJ4", "name": "CYP26B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016198", "map_id": "ENSBTAT00000016198", "name": "CYP26B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDT5", "map_id": "E1BDT5", "name": "CYP26C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071407", "map_id": "none", "name": "RAR:RXR binds SUMO-CRABP2:atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071399", "map_id": "none", "name": "RARB:RXRB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3X6X1", "map_id": "G3X6X1", "name": "RARB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015305", "map_id": "ENSBTAT00000015305", "name": "RARB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7I6", "map_id": "A6H7I6", "name": "RXRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000860", "map_id": "ENSBTAT00000000860", "name": "RXRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071403", "map_id": "none", "name": "SUMO-K102-CRABP2:atRA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LX32", "map_id": "A0A3Q1LX32", "name": "CRABP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087158", "map_id": "ENSBTAT00000087158", "name": "CRABP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071405", "map_id": "none", "name": "SUMO-CRABP2:atRA:RAR:RXR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071397", "map_id": "none", "name": "SUMO-CRABP2 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071393", "map_id": "A0A3Q1LX32", "name": "CRABP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071395", "map_id": "none", "name": "SUMO-K102-CRABP2:atRA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072628", "map_id": "none", "name": "SUMO-CRABP2 dissociates from atRA:RAR:RXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072626", "map_id": "none", "name": "atRA:RAR:RXR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10071401", "map_id": "A0A3Q1LX32", "name": "CRABP2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10072630", "map_id": "none", "name": "SUMO-CRABP2:atRA translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090456", "map_id": "none", "name": "Co-repressor complex dissociates from the transcription unit of the ABCA1 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090450", "map_id": "none", "name": "ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q5E9B6", "map_id": "Q5E9B6", "name": "NR1H3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071739", "map_id": "ENSBTAT00000071739", "name": "NR1H3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPA7", "map_id": "F1MPA7", "name": "GPS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013888", "map_id": "ENSBTAT00000013888", "name": "GPS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "B7TCI5", "map_id": "B7TCI5", "name": "TBL1X", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084466", "map_id": "ENSBTAT00000084466", "name": "TBL1X", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSZ9", "map_id": "A0A3Q1MSZ9", "name": "TBL1XR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087441", "map_id": "ENSBTAT00000087441", "name": "TBL1XR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0W0", "map_id": "F1N0W0", "name": "HDAC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023086", "map_id": "ENSBTAT00000023086", "name": "HDAC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGM4", "map_id": "F1MGM4", "name": "NCOR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061343", "map_id": "ENSBTAT00000061343", "name": "NCOR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MY21", "map_id": "A0A3Q1MY21", "name": "NCOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086068", "map_id": "ENSBTAT00000086068", "name": "NCOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_192060", "map_id": "CHEBI:34310", "name": "24OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "CHEBI:67237", "map_id": "CHEBI:67237", "name": "CHEBI:67237", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9024328", "map_id": "CHEBI:76591", "name": "27-OH-CHOL", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:41633", "map_id": "CHEBI:41633", "name": "CHEBI:41633", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090454", "map_id": "none", "name": "ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10090444", "map_id": "none", "name": "NCOR:GPS2:TBL1:HDAC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090559", "map_id": "none", "name": "NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10047785", "map_id": "G3N0C2", "name": "NCOA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000064008", "map_id": "ENSBTAT00000064008", "name": "NCOA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090557", "map_id": "none", "name": "NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3N0C2", "map_id": "G3N0C2", "name": "NCOA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090563", "map_id": "none", "name": "NCOA1 recruits EP300 to the ABCA1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10053052", "map_id": "E1B8D6", "name": "EP300", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10090561", "map_id": "none", "name": "EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090452", "map_id": "none", "name": "Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090448", "map_id": "none", "name": "ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_9024383", "map_id": "none", "name": "NR1H3, NR1H2 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090555", "map_id": "none", "name": "Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090551", "map_id": "none", "name": "UGT1A3 gene:NR1H2,3:RXR:NCOR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10090553", "map_id": "none", "name": "UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090571", "map_id": "none", "name": "NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090565", "map_id": "none", "name": "UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10090569", "map_id": "none", "name": "UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090567", "map_id": "none", "name": "Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044694", "map_id": "none", "name": "NCOR1, NCOR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090712", "map_id": "none", "name": "27-hydroxysterol binds ESR1, ESR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10045570", "map_id": "Q9XSB5", "name": "ESR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000005899", "map_id": "ENSBTAT00000005899", "name": "ESR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090710", "map_id": "none", "name": "27-OH-CHOL:ESR1,2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9XSB5", "map_id": "Q9XSB5", "name": "ESR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092314", "map_id": "none", "name": "ESTG binds ESR2:chaperone complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086682", "map_id": "none", "name": "ESR2:chaperone complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P26882", "map_id": "P26882", "name": "PPID", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022180", "map_id": "ENSBTAT00000022180", "name": "PPID", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1254400", "map_id": "CHEBI:50114", "name": "ESTG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10086684", "map_id": "none", "name": "ESTG:ESR2:chaperone complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089761", "map_id": "none", "name": "EP300 is recruited to MYC and BCL2 genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089757", "map_id": "none", "name": "MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2HJ27", "map_id": "Q2HJ27", "name": "MYC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076263", "map_id": "ENSBTAT00000076263", "name": "MYC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F2Z4J1", "map_id": "F2Z4J1", "name": "H2AC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056983", "map_id": "ENSBTAT00000056983", "name": "H2AC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9F8", "map_id": "Q5E9F8", "name": "H3-3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034695", "map_id": "ENSBTAT00000034695", "name": "H3-3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089759", "map_id": "none", "name": "MYC gene, BCL2 gene:HIST1H2AC nuclesome:ESR1:ESTG:EP300", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10091115", "map_id": "none", "name": "MMPs cleave HB-EGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091106", "map_id": "E1BIN8", "name": "HBEGF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10091108", "map_id": "E1BIN8", "name": "HBEGF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10040221", "map_id": "E1BIN8", "name": "HBEGF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10091110", "map_id": "none", "name": "MMP2,3,7,9", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10091113", "map_id": "none", "name": "S1P:S1PR3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QR17", "map_id": "A6QR17", "name": "S1PR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015111", "map_id": "ENSBTAT00000015111", "name": "S1PR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_419305", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10091275", "map_id": "none", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091269", "map_id": "none", "name": "PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091273", "map_id": "none", "name": "PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091260", "map_id": "none", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091252", "map_id": "none", "name": "PDPK1:PIP3:p-T410-PRKCZ", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091257", "map_id": "none", "name": "PDPK1:PIP3:pS, p-T410 PRKCZ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091271", "map_id": "none", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091151", "map_id": "none", "name": "PTK2 binds activated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040243", "map_id": "none", "name": "EGF-like ligands:p-6Y EGFR dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043033", "map_id": "A0A3Q1N508", "name": "PTK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000085237", "map_id": "ENSBTAT00000085237", "name": "phospho-PTK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091149", "map_id": "none", "name": "EGF-like ligands:p-6Y EGFR:PTK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N508", "map_id": "A0A3Q1N508", "name": "phospho-PTK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091156", "map_id": "none", "name": "PTK2 autophosphorylates downstream of EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091153", "map_id": "none", "name": "EGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091118", "map_id": "none", "name": "AKT-phosphorylated FOXO3 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10042685", "map_id": "F1N4K5", "name": "phospho-FOXO3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000014920", "map_id": "ENSBTAT00000014920", "name": "phospho-FOXO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091011", "map_id": "F1N4K5", "name": "phospho-FOXO3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091267", "map_id": "none", "name": "p-S10 CDKN1B translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091263", "map_id": "A6QLS3", "name": "phospho-CDKN1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000024297", "map_id": "ENSBTAT00000024297", "name": "phospho-CDKN1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091265", "map_id": "A6QLS3", "name": "phospho-CDKN1B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050265", "map_id": "E1BE98", "name": "XPO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000017629", "map_id": "ENSBTAT00000017629", "name": "XPO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091158", "map_id": "none", "name": "S1P binds S1PR3 in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5218688", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10046309", "map_id": "A6QR17", "name": "S1PR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10086662", "map_id": "none", "name": "ESR dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086658", "map_id": "none", "name": "ESR2:ESTG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086660", "map_id": "none", "name": "ESR2 dimer:ESTG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086575", "map_id": "none", "name": "CRHR2-2 binds CRH,UCN,UCN2,UCN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048262", "map_id": "A0A3Q1N5S8", "name": "CRHR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000081022", "map_id": "ENSBTAT00000081022", "name": "CRHR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086571", "map_id": "none", "name": "CRH,UCN,UCN2,UCN3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MKP4", "map_id": "F1MKP4", "name": "UCN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025398", "map_id": "ENSBTAT00000025398", "name": "UCN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q95MI6", "map_id": "Q95MI6", "name": "CRH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047063", "map_id": "ENSBTAT00000047063", "name": "CRH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086573", "map_id": "none", "name": "CRHR2-2:CRH,UCN,UCN2,UCN3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N5S8", "map_id": "A0A3Q1N5S8", "name": "CRHR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048270", "map_id": "none", "name": "CRHR1,CRHR2-1 binds CRH,UCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048266", "map_id": "Q95MI6", "name": "CRH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048268", "map_id": "none", "name": "CRHR1,CRHR2-1:CRH,UCN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049681", "map_id": "none", "name": "EGF-TM7 receptors bind chondroitin sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049677", "map_id": "none", "name": "EGF-7TMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M8L4", "map_id": "A0A3Q1M8L4", "name": "LOC112447333", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082095", "map_id": "ENSBTAT00000082095", "name": "LOC112447333", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0R0", "map_id": "A0A3Q1M0R0", "name": "ADGRE5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081916", "map_id": "ENSBTAT00000081916", "name": "ADGRE5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049679", "map_id": "none", "name": "EGF-7TMs:CHS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051907", "map_id": "none", "name": "CD97 binds CD55", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049671", "map_id": "A0A3Q1M0R0", "name": "ADGRE5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10051903", "map_id": "A0A3Q1LQX2", "name": "CD55", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000078403", "map_id": "ENSBTAT00000078403", "name": "CD55", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051905", "map_id": "none", "name": "CD55:CD97", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LQX2", "map_id": "A0A3Q1LQX2", "name": "CD55", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086565", "map_id": "none", "name": "CRHBP binds CRH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10086561", "map_id": "A7MBA3", "name": "CRHBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000026905", "map_id": "ENSBTAT00000026905", "name": "CRHBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086563", "map_id": "none", "name": "CRHBP:CRH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A7MBA3", "map_id": "A7MBA3", "name": "CRHBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048248", "map_id": "none", "name": "Glucagon-like receptor 2 binds GLP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048244", "map_id": "P01272", "name": "GCG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000000972", "map_id": "ENSBTAT00000000972", "name": "GCG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048242", "map_id": "E1BAY1", "name": "GLP2R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000006662", "map_id": "ENSBTAT00000006662", "name": "GLP2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048246", "map_id": "none", "name": "GLP2R:GCG(146-178)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BAY1", "map_id": "E1BAY1", "name": "GLP2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01272", "map_id": "P01272", "name": "GCG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048282", "map_id": "none", "name": "Secretin receptor binds secretin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048278", "map_id": "A0A3Q1M5G0", "name": "SCTR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071185", "map_id": "ENSBTAT00000071185", "name": "SCTR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048274", "map_id": "A0A3Q1MB83", "name": "SCT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000079270", "map_id": "ENSBTAT00000079270", "name": "SCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048280", "map_id": "none", "name": "SCTR:SCT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MB83", "map_id": "A0A3Q1MB83", "name": "SCT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5G0", "map_id": "A0A3Q1M5G0", "name": "SCTR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048304", "map_id": "none", "name": "VIP receptors bind VIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048290", "map_id": "P81401", "name": "VIP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000017827", "map_id": "ENSBTAT00000017827", "name": "VIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048300", "map_id": "none", "name": "VIPR1,VIPR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MIT6", "map_id": "F1MIT6", "name": "VIPR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047461", "map_id": "ENSBTAT00000047461", "name": "VIPR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MF07", "map_id": "F1MF07", "name": "VIPR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008625", "map_id": "ENSBTAT00000008625", "name": "VIPR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048302", "map_id": "none", "name": "VIPR1,VIPR2:VIP(125-152)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P81401", "map_id": "P81401", "name": "VIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038918", "map_id": "none", "name": "Glucagon binds to Glucagon receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038912", "map_id": "A7MBH4", "name": "CYSLTR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000023275", "map_id": "ENSBTAT00000023275", "name": "CYSLTR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038908", "map_id": "P01272", "name": "GCG", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038916", "map_id": "none", "name": "GCGR:GCG(53-81)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7MBH4", "map_id": "A7MBH4", "name": "CYSLTR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048326", "map_id": "none", "name": "Parathyroid hormone receptor can bind parathyroid hormone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10048322", "map_id": "none", "name": "PTH1R,PTH2R ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P58073", "map_id": "P58073", "name": "PTHLH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043154", "map_id": "ENSBTAT00000043154", "name": "PTHLH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9U9", "map_id": "E1B9U9", "name": "PTH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001408", "map_id": "ENSBTAT00000001408", "name": "PTH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048312", "map_id": "E1B7Q8", "name": "PTH2R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000061196", "map_id": "ENSBTAT00000061196", "name": "PTH2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048324", "map_id": "none", "name": "PTH1R,PTH2R:PTH1R,PTH2R ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B7Q8", "map_id": "E1B7Q8", "name": "PTH2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091763", "map_id": "none", "name": "CYSLTR1 binds CYSLTR1 antagonists", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045862", "map_id": "A5PKG3", "name": "CYSLTR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000034352", "map_id": "ENSBTAT00000034352", "name": "CYSLTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9684615", "map_id": "none", "name": "CYSLTR1 antagonists", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10091761", "map_id": "none", "name": "CYSLTR1:CYSLTR1 antagonists", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5PKG3", "map_id": "A5PKG3", "name": "CYSLTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047378", "map_id": "none", "name": "UDP/CysLT receptor can bind cysteinyl leukotrienes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045892", "map_id": "A2VEA2", "name": "GPR17", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008214", "map_id": "ENSBTAT00000008214", "name": "GPR17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_416372", "map_id": "none", "name": "LTC4,LTD4,LTE4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:15650", "map_id": "CHEBI:15650", "name": "CHEBI:15650", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046259", "map_id": "none", "name": "GPR17:Cysteinyl leukotrienes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A2VEA2", "map_id": "A2VEA2", "name": "GPR17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047396", "map_id": "none", "name": "BLT receptors can bind LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045934", "map_id": "none", "name": "LTB4R,LTB4R2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T181", "map_id": "Q3T181", "name": "LTB4R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036478", "map_id": "ENSBTAT00000036478", "name": "LTB4R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRY8", "map_id": "F1MRY8", "name": "LTB4R2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054992", "map_id": "ENSBTAT00000054992", "name": "LTB4R2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_416436", "map_id": "CHEBI:15647", "name": "LTB4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045936", "map_id": "none", "name": "LTB4R,LTB4R2:LTB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091812", "map_id": "none", "name": "CYSLTR1 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045864", "map_id": "none", "name": "CYSLTR1:LTC4,LTD4,LTE4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047398", "map_id": "none", "name": "CYSLT2 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038914", "map_id": "A7MBH4", "name": "CYSLTR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10045866", "map_id": "none", "name": "CYSLTR2:LTC4,LTD4,LTE4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047374", "map_id": "none", "name": "DP1 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_416911", "map_id": "CHEBI:15555", "name": "PGD2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10047370", "map_id": "A0A452DI56", "name": "PTGDR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008808", "map_id": "ENSBTAT00000008808", "name": "PTGDR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047372", "map_id": "none", "name": "PTGDR:PGD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DI56", "map_id": "A0A452DI56", "name": "PTGDR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047376", "map_id": "none", "name": "EP1 receptor can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_391930", "map_id": "CHEBI:15551", "name": "PGE2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045990", "map_id": "F1MUY4", "name": "PTGER1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000046806", "map_id": "ENSBTAT00000046806", "name": "PTGER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045992", "map_id": "none", "name": "PTGER1:PGE2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MUY4", "map_id": "F1MUY4", "name": "PTGER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047394", "map_id": "none", "name": "EP2 and EP4 receptors can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047390", "map_id": "none", "name": "PTGER2,PTGER4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N2L8", "map_id": "F1N2L8", "name": "PTGER2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002800", "map_id": "ENSBTAT00000002800", "name": "PTGER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZJ8", "map_id": "F1MZJ8", "name": "PTGER4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019930", "map_id": "ENSBTAT00000019930", "name": "PTGER4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047392", "map_id": "none", "name": "PTGER2,PTGER4:PGE2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047380", "map_id": "none", "name": "TP receptor can bind thromboxane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_391932", "map_id": "CHEBI:15627", "name": "TXA2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045856", "map_id": "Q95125", "name": "TBXA2R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019892", "map_id": "ENSBTAT00000019892", "name": "TBXA2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045858", "map_id": "none", "name": "TBXA2R:TXA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q95125", "map_id": "Q95125", "name": "TBXA2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047366", "map_id": "none", "name": "DP2 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046263", "map_id": "A0A3Q1N2W9", "name": "PTGDR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000066986", "map_id": "ENSBTAT00000066986", "name": "PTGDR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046265", "map_id": "none", "name": "PTGDR2:PGD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N2W9", "map_id": "A0A3Q1N2W9", "name": "PTGDR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047364", "map_id": "none", "name": "Oxoeicosanoid receptor can bind oxoeicosanoid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_416428", "map_id": "CHEBI:52449", "name": "5-oxoETE", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046299", "map_id": "F1MCJ0", "name": "OXER1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005326", "map_id": "ENSBTAT00000005326", "name": "OXER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046301", "map_id": "none", "name": "OXER1:5-oxoETE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCJ0", "map_id": "F1MCJ0", "name": "OXER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049657", "map_id": "none", "name": "G-protein coupled bile acid receptor binds lithocholic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_444840", "map_id": "none", "name": "Bile acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_5357505", "map_id": "CHEBI:28834", "name": "DCA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_193451", "map_id": "CHEBI:16359", "name": "cholate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_176655", "map_id": "CHEBI:16325", "name": "LCA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:16755", "map_id": "CHEBI:16755", "name": "CHEBI:16755", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049653", "map_id": "Q862A9", "name": "GPBAR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005120", "map_id": "ENSBTAT00000005120", "name": "GPBAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049655", "map_id": "none", "name": "GPBAR1: Bile acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q862A9", "map_id": "Q862A9", "name": "GPBAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047354", "map_id": "none", "name": "Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047350", "map_id": "none", "name": "Thyrotropin, Thyrostimulin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P01223", "map_id": "P01223", "name": "TSHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008264", "map_id": "ENSBTAT00000008264", "name": "TSHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD70", "map_id": "E1BD70", "name": "GPHA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009286", "map_id": "ENSBTAT00000009286", "name": "GPHA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A0F7RPV8", "map_id": "A0A0F7RPV8", "name": "GPB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075524", "map_id": "ENSBTAT00000075524", "name": "GPB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047338", "map_id": "F1N4F6", "name": "TSHR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000052615", "map_id": "ENSBTAT00000052615", "name": "TSHR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047352", "map_id": "none", "name": "TSHR:Thyrotropin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N4F6", "map_id": "F1N4F6", "name": "TSHR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047362", "map_id": "none", "name": "Luteinizing hormone receptor can bind LH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047358", "map_id": "A0A140T893", "name": "LHCGR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000022047", "map_id": "ENSBTAT00000022047", "name": "LHCGR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047360", "map_id": "none", "name": "LH receptor:LH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A140T893", "map_id": "A0A140T893", "name": "LHCGR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047334", "map_id": "none", "name": "Gonadotropin-releasing hormone receptors can bind GNRH I and II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045798", "map_id": "none", "name": "GNRH ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q0VBW7", "map_id": "Q0VBW7", "name": "GNRH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000188", "map_id": "ENSBTAT00000000188", "name": "GNRH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7J7", "map_id": "A0A3Q1M7J7", "name": "GNRH2(24-33)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069568", "map_id": "ENSBTAT00000069568", "name": "GNRH2(24-33)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045788", "map_id": "P32236", "name": "GNRHR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000000559", "map_id": "ENSBTAT00000000559", "name": "GNRHR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045800", "map_id": "none", "name": "GnRH receptor:GNRH ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P32236", "map_id": "P32236", "name": "GNRHR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049659", "map_id": "none", "name": "HCAR2 binds HCAR2 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_3296262", "map_id": "none", "name": "HCAR2 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:20067", "map_id": "CHEBI:20067", "name": "CHEBI:20067", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_197230", "map_id": "CHEBI:15940", "name": "NCA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046459", "map_id": "G3N168", "name": "LOC527744", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065393", "map_id": "ENSBTAT00000065393", "name": "LOC527744", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046461", "map_id": "none", "name": "HCAR2:HCAR2 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N168", "map_id": "G3N168", "name": "LOC527744", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048208", "map_id": "none", "name": "Light stimulates opsin receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_419777", "map_id": "CHEBI:30212", "name": "Photon", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048204", "map_id": "none", "name": "Light-sensing opsins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "Q9BGI7", "map_id": "Q9BGI7", "name": "OPN1LW", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027054", "map_id": "ENSBTAT00000027054", "name": "OPN1LW", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P02699", "map_id": "P02699", "name": "RHO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001730", "map_id": "ENSBTAT00000001730", "name": "RHO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P51490", "map_id": "P51490", "name": "OPN1SW", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021912", "map_id": "ENSBTAT00000021912", "name": "OPN1SW", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048206", "map_id": "none", "name": "Opsins:photon", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "reaction_10048214", "map_id": "none", "name": "Melanospin is stimulated by light", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045850", "map_id": "E1BEK2", "name": "OPN4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "ENSBTAT00000040059", "map_id": "ENSBTAT00000040059", "name": "OPN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045852", "map_id": "none", "name": "Melanospin:photon", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "E1BEK2", "map_id": "E1BEK2", "name": "OPN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045180", "map_id": "none", "name": "Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045172", "map_id": "E1BH62", "name": "XCL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000013116", "map_id": "ENSBTAT00000013116", "name": "XCL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045176", "map_id": "F1N2D2", "name": "XCR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000026663", "map_id": "ENSBTAT00000026663", "name": "XCR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045178", "map_id": "none", "name": "XCR1:XCL1,XCL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N2D2", "map_id": "F1N2D2", "name": "XCR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BH62", "map_id": "E1BH62", "name": "XCL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067358", "map_id": "none", "name": "CCRL2 binds CCL19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049514", "map_id": "Q3ZBN3", "name": "CCL19", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000016850", "map_id": "ENSBTAT00000016850", "name": "CCL19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067354", "map_id": "Q0II78", "name": "CCRL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008096", "map_id": "ENSBTAT00000008096", "name": "CCRL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067356", "map_id": "none", "name": "CCRL2:CCL19", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0II78", "map_id": "Q0II78", "name": "CCRL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBN3", "map_id": "Q3ZBN3", "name": "CCL19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045168", "map_id": "none", "name": "Receptor CCR6 binds CCL20 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045164", "map_id": "Q8SQB1", "name": "CCL20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000028430", "map_id": "ENSBTAT00000028430", "name": "CCL20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045160", "map_id": "F1MT56", "name": "CCR6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000037034", "map_id": "ENSBTAT00000037034", "name": "CCR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045166", "map_id": "none", "name": "CCR6:CCL20", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MT56", "map_id": "F1MT56", "name": "CCR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8SQB1", "map_id": "Q8SQB1", "name": "CCL20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045072", "map_id": "none", "name": "Receptors CCR3, 4 and 5 bind CCL5 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045054", "map_id": "O97919", "name": "CCL5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000082438", "map_id": "ENSBTAT00000082438", "name": "CCL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045068", "map_id": "none", "name": "CCR3,4,5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q2HJ17", "map_id": "Q2HJ17", "name": "CCR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010652", "map_id": "ENSBTAT00000010652", "name": "CCR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MP16", "map_id": "F1MP16", "name": "CCR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001762", "map_id": "ENSBTAT00000001762", "name": "CCR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLA5", "map_id": "A6QLA5", "name": "CCR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049352", "map_id": "ENSBTAT00000049352", "name": "CCR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045070", "map_id": "none", "name": "CCR3,4,5:CCL5(24-91)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O97919", "map_id": "O97919", "name": "CCL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049520", "map_id": "none", "name": "Receptor CCR11 binds CCL19, CCL21 & CCL25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049510", "map_id": "P35350", "name": "ACKR4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000026082", "map_id": "ENSBTAT00000026082", "name": "ACKR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049516", "map_id": "none", "name": "CCL19, CCL21, CCL25", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q1RMQ0", "map_id": "Q1RMQ0", "name": "CCL25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007331", "map_id": "ENSBTAT00000007331", "name": "CCL25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049518", "map_id": "none", "name": "CCR11:CCL19,21,25", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P35350", "map_id": "P35350", "name": "ACKR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045106", "map_id": "none", "name": "Receptor CCR9 binds CCL25 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045102", "map_id": "A4IF92", "name": "CCR9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000078248", "map_id": "ENSBTAT00000078248", "name": "CCR9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045098", "map_id": "Q1RMQ0", "name": "CCL25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045104", "map_id": "none", "name": "CCR9:CCL25", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4IF92", "map_id": "A4IF92", "name": "CCR9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045268", "map_id": "none", "name": "Receptors CXCR4 and 7 bind CXCL12 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045264", "map_id": "A0A3Q1M085", "name": "CXCL12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000077980", "map_id": "ENSBTAT00000077980", "name": "CXCL12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045260", "map_id": "none", "name": "CXCR4,7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P25930", "map_id": "P25930", "name": "CXCR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001406", "map_id": "ENSBTAT00000001406", "name": "CXCR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IF77", "map_id": "A4IF77", "name": "ACKR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024512", "map_id": "ENSBTAT00000024512", "name": "ACKR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045266", "map_id": "none", "name": "CXCR4,7:CXCL12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M085", "map_id": "A0A3Q1M085", "name": "CXCL12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083880", "map_id": "none", "name": "CCR8 binds CCL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046469", "map_id": "E1BAG6", "name": "CCL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000047653", "map_id": "ENSBTAT00000047653", "name": "CCL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045080", "map_id": "F6RDR3", "name": "CCR8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000020577", "map_id": "ENSBTAT00000020577", "name": "CCR8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046471", "map_id": "none", "name": "CCR8:CCL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6RDR3", "map_id": "F6RDR3", "name": "CCR8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAG6", "map_id": "E1BAG6", "name": "CCL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045196", "map_id": "none", "name": "Receptor CXCR6 binds CXCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045188", "map_id": "Q5EA94", "name": "CXCR6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000020855", "map_id": "ENSBTAT00000020855", "name": "CXCR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045192", "map_id": "Q29RT9", "name": "CXCL16", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000024371", "map_id": "ENSBTAT00000024371", "name": "CXCL16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045194", "map_id": "none", "name": "CXCR6:CXCL16", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q29RT9", "map_id": "Q29RT9", "name": "CXCL16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA94", "map_id": "Q5EA94", "name": "CXCR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045280", "map_id": "none", "name": "Receptor CXCR3 binds ligands CXCL9 to 11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045276", "map_id": "Q5MD61", "name": "CXCR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019690", "map_id": "ENSBTAT00000019690", "name": "CXCR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045272", "map_id": "A9QWP9", "name": "CXCL9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000075648", "map_id": "ENSBTAT00000075648", "name": "CXCL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045278", "map_id": "none", "name": "CXCR3:CXCR3 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A9QWP9", "map_id": "A9QWP9", "name": "CXCL9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5MD61", "map_id": "Q5MD61", "name": "CXCR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049570", "map_id": "none", "name": "Receptor ACKR2 binds most inflammatory CC chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049524", "map_id": "A0A3Q1LTZ4", "name": "ACKR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068509", "map_id": "ENSBTAT00000068509", "name": "ACKR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049566", "map_id": "none", "name": "CCBP2 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P28291", "map_id": "P28291", "name": "CCL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013146", "map_id": "ENSBTAT00000013146", "name": "CCL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKF1", "map_id": "A5PKF1", "name": "CCL22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023564", "map_id": "ENSBTAT00000023564", "name": "CCL22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QA1", "map_id": "Q17QA1", "name": "CCL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009446", "map_id": "ENSBTAT00000009446", "name": "CCL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGB8", "map_id": "E1BGB8", "name": "LOC616364", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004257", "map_id": "ENSBTAT00000004257", "name": "LOC616364", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P82943", "map_id": "P82943", "name": "CCL3L1(26-93)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013399", "map_id": "ENSBTAT00000013399", "name": "CCL3L1(26-93)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTV3", "map_id": "A0A3Q1LTV3", "name": "LOC508666", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071668", "map_id": "ENSBTAT00000071668", "name": "LOC508666", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NB11", "map_id": "A0A3Q1NB11", "name": "LOC100297044", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085385", "map_id": "ENSBTAT00000085385", "name": "LOC100297044", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYS4", "map_id": "F1MYS4", "name": "CCL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035430", "map_id": "ENSBTAT00000035430", "name": "CCL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9TTS6", "map_id": "Q9TTS6", "name": "CCL11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005406", "map_id": "ENSBTAT00000005406", "name": "CCL11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIF0", "map_id": "F1MIF0", "name": "CCL17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001579", "map_id": "ENSBTAT00000001579", "name": "CCL17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049568", "map_id": "none", "name": "ACKR2:CCBP2 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LTZ4", "map_id": "A0A3Q1LTZ4", "name": "ACKR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045156", "map_id": "none", "name": "Receptor CCR10 binds CCL27 and 28 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045142", "map_id": "D9ZDE4", "name": "CCR10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000025420", "map_id": "ENSBTAT00000025420", "name": "CCR10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045152", "map_id": "none", "name": "CCL27,28", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MZ86", "map_id": "F1MZ86", "name": "CCL27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019846", "map_id": "ENSBTAT00000019846", "name": "CCL27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6YT15", "map_id": "A6YT15", "name": "CCL28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002036", "map_id": "ENSBTAT00000002036", "name": "CCL28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045154", "map_id": "none", "name": "CCR10:CCL27,28", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "D9ZDE4", "map_id": "D9ZDE4", "name": "CCR10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049639", "map_id": "none", "name": "CXCR5 binds CXCL13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046161", "map_id": "Q56JW7", "name": "CXCL13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000011164", "map_id": "ENSBTAT00000011164", "name": "CXCL13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046157", "map_id": "G3N3U0", "name": "CXCR5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000063808", "map_id": "ENSBTAT00000063808", "name": "CXCR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046163", "map_id": "none", "name": "CXCR5:CXCL13", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N3U0", "map_id": "G3N3U0", "name": "CXCR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JW7", "map_id": "Q56JW7", "name": "CXCL13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045094", "map_id": "none", "name": "Receptors CCR1, 2 and 8 bind CCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045090", "map_id": "A0A3Q1M976", "name": "CCL16", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000079349", "map_id": "ENSBTAT00000079349", "name": "CCL16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045086", "map_id": "none", "name": "CCR1,2,8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3S5ZP45", "map_id": "A0A3S5ZP45", "name": "CCR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018066", "map_id": "ENSBTAT00000018066", "name": "CCR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0JN72", "map_id": "A0JN72", "name": "CCR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025880", "map_id": "ENSBTAT00000025880", "name": "CCR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045092", "map_id": "none", "name": "CCR1,2,8:CCL16", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M976", "map_id": "A0A3Q1M976", "name": "CCL16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091037", "map_id": "none", "name": "ARBs bind AGRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9615246", "map_id": "none", "name": "ARBs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045250", "map_id": "P25104", "name": "AGTR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000063575", "map_id": "ENSBTAT00000063575", "name": "AGTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091035", "map_id": "none", "name": "ARBs:AGTR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P25104", "map_id": "P25104", "name": "AGTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046731", "map_id": "none", "name": "AVP(20-28) binds AVPR1A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045814", "map_id": "A0A3Q1LXY0", "name": "AVP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000076190", "map_id": "ENSBTAT00000076190", "name": "AVP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045810", "map_id": "none", "name": "AVPR1A,B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6PV87", "map_id": "F6PV87", "name": "AVPR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009443", "map_id": "ENSBTAT00000009443", "name": "AVPR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ME85", "map_id": "F1ME85", "name": "AVPR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022994", "map_id": "ENSBTAT00000022994", "name": "AVPR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045816", "map_id": "none", "name": "AVPR1A,B:AVP(20-28)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LXY0", "map_id": "A0A3Q1LXY0", "name": "AVP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047483", "map_id": "none", "name": "AVP(20-28) binds AVPR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047479", "map_id": "P48044", "name": "AVPR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065044", "map_id": "ENSBTAT00000065044", "name": "phospho-AVPR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047481", "map_id": "none", "name": "AVPR2:AVP(20-28)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P48044", "map_id": "P48044", "name": "phospho-AVPR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046733", "map_id": "none", "name": "Oxytocin receptor bind oxytocin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045970", "map_id": "P56449", "name": "OXTR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000026346", "map_id": "ENSBTAT00000026346", "name": "OXTR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045966", "map_id": "P01175", "name": "OXT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000010554", "map_id": "ENSBTAT00000010554", "name": "OXT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045972", "map_id": "none", "name": "OXTR:OXT(20-28)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P01175", "map_id": "P01175", "name": "OXT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56449", "map_id": "P56449", "name": "OXTR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049661", "map_id": "none", "name": "Prokineticin receptors bind prokineticin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046036", "map_id": "F1MN36", "name": "PROK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000013959", "map_id": "ENSBTAT00000013959", "name": "PROK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046032", "map_id": "Q8SPN1", "name": "PROKR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021097", "map_id": "ENSBTAT00000021097", "name": "PROKR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046038", "map_id": "none", "name": "PROKR1,PROKR2:PROK1,PROK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8SPN1", "map_id": "Q8SPN1", "name": "PROKR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN36", "map_id": "F1MN36", "name": "PROK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046729", "map_id": "none", "name": "Tachykinin receptor 3 (NK3) binds to neurokinin B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045940", "map_id": "P08858", "name": "TAC3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000029067", "map_id": "ENSBTAT00000029067", "name": "TAC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045944", "map_id": "F1N2X0", "name": "TACR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021612", "map_id": "ENSBTAT00000021612", "name": "TACR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045946", "map_id": "none", "name": "TACR3:TAC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N2X0", "map_id": "F1N2X0", "name": "TACR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08858", "map_id": "P08858", "name": "TAC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045406", "map_id": "none", "name": "GPCR neuropeptide receptor binds neuropeptides B and W", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045398", "map_id": "none", "name": "Neuropeptides B/W", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q8MJV4", "map_id": "Q8MJV4", "name": "NPB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018455", "map_id": "ENSBTAT00000018455", "name": "NPB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTH9", "map_id": "A0A3Q1LTH9", "name": "NPW(33-55)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078382", "map_id": "ENSBTAT00000078382", "name": "NPW(33-55)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045402", "map_id": "G5E5J0", "name": "NPBWR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021510", "map_id": "ENSBTAT00000021510", "name": "NPBWR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045404", "map_id": "none", "name": "Neuropeptides B/W receptor:neuropeptides B/W", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E5J0", "map_id": "G5E5J0", "name": "NPBWR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045362", "map_id": "none", "name": "Nociceptin receptor binds to nociceptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045358", "map_id": "A0A3Q1LWC2", "name": "OPRL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000084136", "map_id": "ENSBTAT00000084136", "name": "OPRL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045354", "map_id": "O62647", "name": "PNOC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000000695", "map_id": "ENSBTAT00000000695", "name": "PNOC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045360", "map_id": "none", "name": "Nociceptin receptor:Nociceptin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O62647", "map_id": "O62647", "name": "PNOC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWC2", "map_id": "A0A3Q1LWC2", "name": "OPRL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046773", "map_id": "none", "name": "POMC(138-176) binds MC2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046769", "map_id": "P01190", "name": "POMC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046767", "map_id": "P34974", "name": "MC2R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014661", "map_id": "ENSBTAT00000014661", "name": "MC2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046771", "map_id": "none", "name": "POMC(138-176):MC2R", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P34974", "map_id": "P34974", "name": "MC2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01190", "map_id": "P01190", "name": "POMC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045332", "map_id": "none", "name": "Bradykinin receptors B1 and B2 bind to bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038198", "map_id": "A0A140T8C8", "name": "KNG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045328", "map_id": "A0A3Q1MXN7", "name": "BDKRB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000078035", "map_id": "ENSBTAT00000078035", "name": "BDKRB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045330", "map_id": "none", "name": "Bradykinin receptor:Bradykinin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MXN7", "map_id": "A0A3Q1MXN7", "name": "BDKRB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053335", "map_id": "none", "name": "Neuromedin-U receptors bind neuromedins U, S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046114", "map_id": "E1BP23", "name": "NMU", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000061371", "map_id": "ENSBTAT00000061371", "name": "NMU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046110", "map_id": "none", "name": "NMUR1,NMUR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MY53", "map_id": "F1MY53", "name": "NMUR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023519", "map_id": "ENSBTAT00000023519", "name": "NMUR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DII4", "map_id": "A0A452DII4", "name": "NMUR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014782", "map_id": "ENSBTAT00000014782", "name": "NMUR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046116", "map_id": "none", "name": "NMUR1,NMUR2:NMU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BP23", "map_id": "E1BP23", "name": "NMU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054775", "map_id": "none", "name": "NMUR2 binds neuromedin-S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046102", "map_id": "A0A452DKE4", "name": "NMS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000048447", "map_id": "ENSBTAT00000048447", "name": "NMS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046098", "map_id": "A0A452DII4", "name": "NMUR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10046104", "map_id": "none", "name": "NMUR2:NMS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DKE4", "map_id": "A0A452DKE4", "name": "NMS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046953", "map_id": "none", "name": "Proteinase-activated receptors can bind thrombin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045984", "map_id": "none", "name": "Proteinase-activated receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCC4", "map_id": "F1MCC4", "name": "F2RL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012283", "map_id": "ENSBTAT00000012283", "name": "F2RL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4J9", "map_id": "F1N4J9", "name": "F2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026902", "map_id": "ENSBTAT00000026902", "name": "F2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFB7", "map_id": "A4IFB7", "name": "F2RL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001191", "map_id": "ENSBTAT00000001191", "name": "F2RL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037577", "map_id": "none", "name": "activated thrombin (factor IIa)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A452DI66", "map_id": "A0A452DI66", "name": "F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009406", "map_id": "ENSBTAT00000009406", "name": "F2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045986", "map_id": "none", "name": "Thrombin:Proteinase-activated receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10045384", "map_id": "none", "name": "Somatostatin receptors bind somatostatin and cortistatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045366", "map_id": "G3N364", "name": "CORT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000063299", "map_id": "ENSBTAT00000063299", "name": "CORT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045380", "map_id": "none", "name": "Somatostatin receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BFV6", "map_id": "E1BFV6", "name": "SSTR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008645", "map_id": "ENSBTAT00000008645", "name": "SSTR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWT4", "map_id": "G3MWT4", "name": "SSTR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011728", "map_id": "ENSBTAT00000011728", "name": "SSTR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MV99", "map_id": "F1MV99", "name": "SSTR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052225", "map_id": "ENSBTAT00000052225", "name": "SSTR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045382", "map_id": "none", "name": "Somatostatin receptor:somatostatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N364", "map_id": "G3N364", "name": "CORT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046763", "map_id": "none", "name": "Melanocortin receptors bind melanocortins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046759", "map_id": "none", "name": "Melanocortin receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P47798", "map_id": "P47798", "name": "MC1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032494", "map_id": "ENSBTAT00000032494", "name": "MC1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8V8", "map_id": "E1B8V8", "name": "MC3R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006185", "map_id": "ENSBTAT00000006185", "name": "MC3R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9GLJ8", "map_id": "Q9GLJ8", "name": "MC4R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026223", "map_id": "ENSBTAT00000026223", "name": "MC4R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56451", "map_id": "P56451", "name": "MC5R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012049", "map_id": "ENSBTAT00000012049", "name": "MC5R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046737", "map_id": "P01190", "name": "POMC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046761", "map_id": "none", "name": "MSH:Melanocortin receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049645", "map_id": "none", "name": "Neuropeptide S receptor binds neuropeptide S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046022", "map_id": "A0A3Q1MSN3", "name": "NPS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000067360", "map_id": "ENSBTAT00000067360", "name": "NPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046026", "map_id": "F1MJZ0", "name": "NPSR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000018290", "map_id": "ENSBTAT00000018290", "name": "NPSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046028", "map_id": "none", "name": "NPSR1:NPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MJZ0", "map_id": "F1MJZ0", "name": "NPSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSN3", "map_id": "A0A3Q1MSN3", "name": "NPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049699", "map_id": "none", "name": "Relaxin receptor 2 binds relaxin 2 and INSL3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10049687", "map_id": "E1BKC2", "name": "RXFP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000020135", "map_id": "ENSBTAT00000020135", "name": "RXFP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049695", "map_id": "none", "name": "Insulin-like peptide 3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "O77801", "map_id": "O77801", "name": "INSL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027848", "map_id": "ENSBTAT00000027848", "name": "INSL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049697", "map_id": "none", "name": "RXFP2:RXFP2 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BKC2", "map_id": "E1BKC2", "name": "RXFP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049683", "map_id": "none", "name": "Relaxin 3 receptor 1 binds relaxin 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046333", "map_id": "F1MSU3", "name": "RXFP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000055041", "map_id": "ENSBTAT00000055041", "name": "RXFP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046329", "map_id": "none", "name": "Relaxin-3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MEV7", "map_id": "F1MEV7", "name": "RLN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036249", "map_id": "ENSBTAT00000036249", "name": "RLN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046335", "map_id": "none", "name": "RXFP3:Relaxin-3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MSU3", "map_id": "F1MSU3", "name": "RXFP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045292", "map_id": "none", "name": "DARC is a non-specific receptor for many chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045284", "map_id": "F1N018", "name": "ACKR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000004179", "map_id": "ENSBTAT00000004179", "name": "ACKR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045288", "map_id": "P79255", "name": "CXCL8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000026275", "map_id": "ENSBTAT00000026275", "name": "CXCL8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045290", "map_id": "none", "name": "DARC:IL8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P79255", "map_id": "P79255", "name": "CXCL8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N018", "map_id": "F1N018", "name": "ACKR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045324", "map_id": "none", "name": "Opioid receptors bind opioid peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045302", "map_id": "none", "name": "Opioid receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N083", "map_id": "F1N083", "name": "OPRD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004157", "map_id": "ENSBTAT00000004157", "name": "OPRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIP6", "map_id": "Q2KIP6", "name": "OPRK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001209", "map_id": "ENSBTAT00000001209", "name": "OPRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045320", "map_id": "none", "name": "Opioid ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10045322", "map_id": "none", "name": "Opioid receptor:opioid ligand", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046735", "map_id": "none", "name": "Endothelin receptors bind endothelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045876", "map_id": "none", "name": "Endothelin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P17322", "map_id": "P17322", "name": "EDN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010649", "map_id": "ENSBTAT00000010649", "name": "EDN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q867A9", "map_id": "Q867A9", "name": "EDN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028571", "map_id": "ENSBTAT00000028571", "name": "EDN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045886", "map_id": "none", "name": "EDNRA,EDNRB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P21450", "map_id": "P21450", "name": "EDNRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018173", "map_id": "ENSBTAT00000018173", "name": "EDNRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28088", "map_id": "P28088", "name": "EDNRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070002", "map_id": "ENSBTAT00000070002", "name": "EDNRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045888", "map_id": "none", "name": "EDNRA,EDNRB:Endothelin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046915", "map_id": "none", "name": "Neuropeptide Y receptors can bind neuropeptide Y-related peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046293", "map_id": "none", "name": "Neuropeptide Y receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B1H0W3", "map_id": "B1H0W3", "name": "NPY2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022125", "map_id": "ENSBTAT00000022125", "name": "NPY2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKB6", "map_id": "F1MKB6", "name": "PPYR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006247", "map_id": "ENSBTAT00000006247", "name": "PPYR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQX6", "map_id": "A6QQX6", "name": "NPY5R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057526", "map_id": "ENSBTAT00000057526", "name": "NPY5R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMU8", "map_id": "Q1RMU8", "name": "NPY1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087149", "map_id": "ENSBTAT00000087149", "name": "NPY1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046275", "map_id": "P51694", "name": "PYY", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000062944", "map_id": "ENSBTAT00000062944", "name": "PYY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046295", "map_id": "none", "name": "Neuropeptide Y receptors:NPY receptor ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P51694", "map_id": "P51694", "name": "PYY", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046917", "map_id": "none", "name": "Neurotensin receptors can bind neurotensins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045950", "map_id": "P01156", "name": "NTS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000006980", "map_id": "ENSBTAT00000006980", "name": "NTS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045960", "map_id": "none", "name": "NTSR1,NTSR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MWG2", "map_id": "F1MWG2", "name": "NTSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028963", "map_id": "ENSBTAT00000028963", "name": "NTSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCZ7", "map_id": "E1BCZ7", "name": "NTSR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004808", "map_id": "ENSBTAT00000004808", "name": "NTSR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045962", "map_id": "none", "name": "NTSR1,NTSR2:NTS(151-163)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P01156", "map_id": "P01156", "name": "NTS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049637", "map_id": "none", "name": "Thyrotropin-releasing hormone receptor binds thyrotropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046006", "map_id": "A6QM11", "name": "TRH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000006982", "map_id": "ENSBTAT00000006982", "name": "TRH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046002", "map_id": "O46639", "name": "TRHR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000026634", "map_id": "ENSBTAT00000026634", "name": "TRHR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046018", "map_id": "none", "name": "TRH:TRHR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O46639", "map_id": "O46639", "name": "TRHR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QM11", "map_id": "A6QM11", "name": "TRH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046919", "map_id": "none", "name": "The Kiss receptor GPR54 binds kisspeptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045902", "map_id": "E1BFS5", "name": "KISS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000028248", "map_id": "ENSBTAT00000028248", "name": "KISS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045898", "map_id": "A0A3Q1MXY0", "name": "KISS1R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000073562", "map_id": "ENSBTAT00000073562", "name": "KISS1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045904", "map_id": "none", "name": "KISS1R:KISS1(68-121)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MXY0", "map_id": "A0A3Q1MXY0", "name": "KISS1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFS5", "map_id": "E1BFS5", "name": "KISS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045350", "map_id": "none", "name": "Apelin receptor binds to apelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045346", "map_id": "A6QL98", "name": "APLNR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000039541", "map_id": "ENSBTAT00000039541", "name": "APLNR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045336", "map_id": "A0A452DJT3", "name": "APLN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000026630", "map_id": "ENSBTAT00000026630", "name": "APLN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045348", "map_id": "none", "name": "APLNR:Apelin peptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DJT3", "map_id": "A0A452DJT3", "name": "APLN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QL98", "map_id": "A6QL98", "name": "APLNR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047864", "map_id": "none", "name": "P2Y5 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045826", "map_id": "A6QL49", "name": "LPAR6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000008730", "map_id": "ENSBTAT00000008730", "name": "LPAR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_417891", "map_id": "CHEBI:52288", "name": "LPA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045828", "map_id": "none", "name": "P2RY5:LPA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QL49", "map_id": "A6QL49", "name": "LPAR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047851", "map_id": "none", "name": "P2Y9 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045838", "map_id": "A4IFV1", "name": "LPAR4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000004269", "map_id": "ENSBTAT00000004269", "name": "LPAR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045840", "map_id": "none", "name": "P2RY9:LPA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4IFV1", "map_id": "A4IFV1", "name": "LPAR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047866", "map_id": "none", "name": "P2Y6 receptor can bind to UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_417888", "map_id": "CHEBI:17659", "name": "UDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045832", "map_id": "F1MTB2", "name": "P2RY6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000057184", "map_id": "ENSBTAT00000057184", "name": "P2RY6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045834", "map_id": "none", "name": "P2RY6:UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MTB2", "map_id": "F1MTB2", "name": "P2RY6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047853", "map_id": "none", "name": "P2Y11 receptor can bind to ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_114570", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045976", "map_id": "F1MU50", "name": "P2RY11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000018000", "map_id": "ENSBTAT00000018000", "name": "P2RY11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045978", "map_id": "none", "name": "P2RY11 :ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MU50", "map_id": "F1MU50", "name": "P2RY11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047868", "map_id": "none", "name": "P2Y4 receptor can bind to UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046215", "map_id": "F1MDW9", "name": "P2RY4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000054975", "map_id": "ENSBTAT00000054975", "name": "P2RY4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_417877", "map_id": "CHEBI:15713", "name": "UTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046217", "map_id": "none", "name": "P2RY4:UTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_29494", "map_id": "CHEBI:15713", "name": "UTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "F1MDW9", "map_id": "F1MDW9", "name": "P2RY4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090956", "map_id": "none", "name": "P2RY12 antagonists bind P2RY12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9611319", "map_id": "none", "name": "P2RY12 antagonists", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046221", "map_id": "Q0IIL0", "name": "P2RY12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064076", "map_id": "ENSBTAT00000064076", "name": "P2RY12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047855", "map_id": "none", "name": "P2RY12:P2RY12 antagonists", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0IIL0", "map_id": "Q0IIL0", "name": "P2RY12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047870", "map_id": "none", "name": "P2RY1 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_114564", "map_id": "CHEBI:456216", "name": "ADP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045820", "map_id": "P48042", "name": "P2RY1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001919", "map_id": "ENSBTAT00000001919", "name": "P2RY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045822", "map_id": "none", "name": "P2RY1:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P48042", "map_id": "P48042", "name": "P2RY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047857", "map_id": "none", "name": "P2RY12 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046223", "map_id": "none", "name": "P2RY12:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047989", "map_id": "none", "name": "The UDP/CysLT (P2Y17) receptor can bind UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045894", "map_id": "none", "name": "GPR17:UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047860", "map_id": "none", "name": "P2Y10 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045844", "map_id": "G3X6Q0", "name": "P2RY10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000011278", "map_id": "ENSBTAT00000011278", "name": "P2RY10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045846", "map_id": "none", "name": "P2RY10:LPA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3X6Q0", "map_id": "G3X6Q0", "name": "P2RY10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047862", "map_id": "none", "name": "P2Y14 receptor can bind to UDP-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046227", "map_id": "Q3SX17", "name": "P2RY14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000027950", "map_id": "ENSBTAT00000027950", "name": "P2RY14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_417855", "map_id": "CHEBI:18066", "name": "UDP-Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046229", "map_id": "none", "name": "P2RY14:UDP-Glc", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3SX17", "map_id": "Q3SX17", "name": "P2RY14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047987", "map_id": "none", "name": "A1 and A3 receptors bind adenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046239", "map_id": "none", "name": "ADORA1,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0VC81", "map_id": "Q0VC81", "name": "ADORA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010057", "map_id": "ENSBTAT00000010057", "name": "ADORA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28190", "map_id": "P28190", "name": "ADORA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072690", "map_id": "ENSBTAT00000072690", "name": "ADORA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_83908", "map_id": "CHEBI:16335", "name": "Ade-Rib", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046241", "map_id": "none", "name": "ADORA1,3:Ade-Rib", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_83909", "map_id": "CHEBI:16335", "name": "Ade-Rib", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10048003", "map_id": "none", "name": "ADORA2A,B bind Ade-Rib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047999", "map_id": "none", "name": "ADORA2A,B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q1LZD0", "map_id": "Q1LZD0", "name": "ADORA2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009974", "map_id": "ENSBTAT00000009974", "name": "ADORA2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKU0", "map_id": "E1BKU0", "name": "ADORA2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077466", "map_id": "ENSBTAT00000077466", "name": "ADORA2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048001", "map_id": "none", "name": "ADORA2A,B:Ade-Rib", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078536", "map_id": "none", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078533", "map_id": "F1MJ26", "name": "PLPPR4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000025329", "map_id": "ENSBTAT00000025329", "name": "PLPPR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048176", "map_id": "none", "name": "LPA-binding receptors bind LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045922", "map_id": "none", "name": "LPAR1,2,3,5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BLD8", "map_id": "E1BLD8", "name": "LPAR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071208", "map_id": "ENSBTAT00000071208", "name": "LPAR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX11", "map_id": "F1MX11", "name": "LPAR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004931", "map_id": "ENSBTAT00000004931", "name": "LPAR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC80", "map_id": "Q3ZC80", "name": "LPAR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005968", "map_id": "ENSBTAT00000005968", "name": "LPAR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M9C6", "map_id": "A0A3Q1M9C6", "name": "LPAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087152", "map_id": "ENSBTAT00000087152", "name": "LPAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045924", "map_id": "none", "name": "LPAR1,2,3,5:LPA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048180", "map_id": "none", "name": "S1PR2-5 bind S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046319", "map_id": "none", "name": "S1PR2-5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1ME98", "map_id": "F1ME98", "name": "S1PR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000492", "map_id": "ENSBTAT00000000492", "name": "S1PR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MV28", "map_id": "F1MV28", "name": "S1PR5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004608", "map_id": "ENSBTAT00000004608", "name": "S1PR5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDV6", "map_id": "A2VDV6", "name": "S1PR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003550", "map_id": "ENSBTAT00000003550", "name": "S1PR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046321", "map_id": "none", "name": "S1PR2-5:S1P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049663", "map_id": "none", "name": "GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046074", "map_id": "none", "name": "pH sensing receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3X6J0", "map_id": "G3X6J0", "name": "GPR132", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007420", "map_id": "ENSBTAT00000007420", "name": "GPR132", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQB3", "map_id": "Q1JQB3", "name": "GPR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024480", "map_id": "ENSBTAT00000024480", "name": "GPR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB13", "map_id": "A7MB13", "name": "GPR65", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016931", "map_id": "ENSBTAT00000016931", "name": "GPR65", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O46685", "map_id": "O46685", "name": "GPR68", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008858", "map_id": "ENSBTAT00000008858", "name": "GPR68", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046076", "map_id": "none", "name": "pH sensing receptors:H+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084702", "map_id": "none", "name": "CMKLR1 binds Resolvin E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9023982", "map_id": "none", "name": "18(S)-RvE1, 18(R)-RvE1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:81559", "map_id": "CHEBI:81559", "name": "CHEBI:81559", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9022660", "map_id": "CHEBI:137038", "name": "18(S)-RvE1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084698", "map_id": "B9VR26", "name": "CMLKR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000029488", "map_id": "ENSBTAT00000029488", "name": "CMLKR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084700", "map_id": "none", "name": "Resolvin E1:CMKLR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B9VR26", "map_id": "B9VR26", "name": "CMLKR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051217", "map_id": "none", "name": "N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_517533", "map_id": "CHEBI:58961", "name": "NAGLY", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046339", "map_id": "Q3T0E9", "name": "GPR18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000007469", "map_id": "ENSBTAT00000007469", "name": "GPR18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046341", "map_id": "none", "name": "GPR18:NAGLY", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T0E9", "map_id": "Q3T0E9", "name": "GPR18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048178", "map_id": "none", "name": "Cannabinoid receptors can bind cannabinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_444560", "map_id": "none", "name": "Cannabinoids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_426030", "map_id": "CHEBI:52392", "name": "2AG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10046255", "map_id": "none", "name": "CNRs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B9P2", "map_id": "E1B9P2", "name": "CNR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025809", "map_id": "ENSBTAT00000025809", "name": "CNR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LGC0", "map_id": "A0A3Q1LGC0", "name": "CNR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067697", "map_id": "ENSBTAT00000067697", "name": "CNR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046257", "map_id": "none", "name": "CNRs:Cannabinoids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10053333", "map_id": "none", "name": "OXGR1 binds 2OG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_561075", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046447", "map_id": "F1MYN3", "name": "OXGR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000035454", "map_id": "ENSBTAT00000035454", "name": "OXGR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046449", "map_id": "none", "name": "OXGR1:2OG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MYN3", "map_id": "F1MYN3", "name": "OXGR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067350", "map_id": "none", "name": "SUCNR1 binds SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_433123", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046441", "map_id": "A0A3Q1M1U4", "name": "SUCNR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068791", "map_id": "ENSBTAT00000068791", "name": "SUCNR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046443", "map_id": "none", "name": "SUCNR1:SUCCA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M1U4", "map_id": "A0A3Q1M1U4", "name": "SUCNR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113536", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10049641", "map_id": "none", "name": "Zinc is an agonist of GPR39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046134", "map_id": "G3MWJ9", "name": "GPR39", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065884", "map_id": "ENSBTAT00000065884", "name": "GPR39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_158417", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046136", "map_id": "none", "name": "GPR39:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MWJ9", "map_id": "G3MWJ9", "name": "GPR39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048172", "map_id": "none", "name": "Melatonin receptors can bind melatonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_419339", "map_id": "CHEBI:16796", "name": "MLT", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046269", "map_id": "A0A3Q1MJK4", "name": "MTNR1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068939", "map_id": "ENSBTAT00000068939", "name": "MTNR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046271", "map_id": "none", "name": "Melatonin receptors:melatonin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MJK4", "map_id": "A0A3Q1MJK4", "name": "MTNR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081580", "map_id": "none", "name": "GPR35 binds kynurenic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_6805204", "map_id": "CHEBI:18344", "name": "Kynurenic acid", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10081576", "map_id": "F1N600", "name": "GPR35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021281", "map_id": "ENSBTAT00000021281", "name": "GPR35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081578", "map_id": "none", "name": "GPR35:Kynurenic acid", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N600", "map_id": "F1N600", "name": "GPR35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067362", "map_id": "none", "name": "HCAR3 binds HCAR3 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_3296330", "map_id": "none", "name": "HCAR3 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:37098", "map_id": "CHEBI:37098", "name": "CHEBI:37098", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046463", "map_id": "G3N168", "name": "LOC527744", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10046465", "map_id": "none", "name": "HCAR3:HCAR3 ligands", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10067364", "map_id": "none", "name": "HCAR1 binds LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046453", "map_id": "B9UM28", "name": "HCAR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001202", "map_id": "ENSBTAT00000001202", "name": "HCAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_373863", "map_id": "CHEBI:422", "name": "LACT", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10046455", "map_id": "none", "name": "HCAR1:LACT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B9UM28", "map_id": "B9UM28", "name": "HCAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048174", "map_id": "none", "name": "PAF receptor binds platelet activating factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_419375", "map_id": "CHEBI:52450", "name": "PAF", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10045996", "map_id": "Q9TTY5", "name": "PTAFR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000038757", "map_id": "ENSBTAT00000038757", "name": "PTAFR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045998", "map_id": "none", "name": "PAF receptor:PAF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9TTY5", "map_id": "Q9TTY5", "name": "PTAFR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083937", "map_id": "none", "name": "GPR183 binds 7alpha,25-dihydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8851675", "map_id": "CHEBI:37623", "name": "7alpha,25-dihydroxycholesterol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046483", "map_id": "Q1RMI1", "name": "GPR183", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000007471", "map_id": "ENSBTAT00000007471", "name": "GPR183", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046485", "map_id": "none", "name": "GPR183:7alpha,25-dihydroxycholesterol", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q1RMI1", "map_id": "Q1RMI1", "name": "GPR183", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_192184", "map_id": "CHEBI:37623", "name": "CHOL3b,7a,25TRIOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10049643", "map_id": "none", "name": "T1R2/T1R3 dimer is a sweet taste receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046501", "map_id": "none", "name": "TAS1R2:TAS1R3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N5V2", "map_id": "F1N5V2", "name": "TAS1R2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038240", "map_id": "ENSBTAT00000038240", "name": "TAS1R2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NND8", "map_id": "A0A3Q1NND8", "name": "TAS1R3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084207", "map_id": "ENSBTAT00000084207", "name": "TAS1R3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_444679", "map_id": "none", "name": "Sweet taste compounds", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32111", "map_id": "CHEBI:32111", "name": "CHEBI:32111", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_188980", "map_id": "CHEBI:17992", "name": "Suc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5696361", "map_id": "CHEBI:2877", "name": "aspartame", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:16296", "map_id": "CHEBI:16296", "name": "CHEBI:16296", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046503", "map_id": "none", "name": "TAS1R2:TAS1R3:Sweet taste compounds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10045138", "map_id": "none", "name": "Metabotropic glutamate receptors bind glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045134", "map_id": "none", "name": "GRM1-8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BAB4", "map_id": "E1BAB4", "name": "GRM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001415", "map_id": "ENSBTAT00000001415", "name": "GRM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJN2", "map_id": "A0A3Q1LJN2", "name": "GRM8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072365", "map_id": "ENSBTAT00000072365", "name": "GRM8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7D8", "map_id": "A5D7D8", "name": "GRM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025275", "map_id": "ENSBTAT00000025275", "name": "GRM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B965", "map_id": "E1B965", "name": "GRM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018119", "map_id": "ENSBTAT00000018119", "name": "GRM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLE8", "map_id": "E1BLE8", "name": "GRM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017342", "map_id": "ENSBTAT00000017342", "name": "GRM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDE0", "map_id": "F1MDE0", "name": "GRM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085376", "map_id": "ENSBTAT00000085376", "name": "GRM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045136", "map_id": "none", "name": "GRM1-8:L-Glu", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10067348", "map_id": "none", "name": "T2Rs bind bitter-tasting compounds", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046435", "map_id": "none", "name": "TAS2Rs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MVK0", "map_id": "F1MVK0", "name": "TAS2R16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045470", "map_id": "ENSBTAT00000045470", "name": "TAS2R16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N090", "map_id": "A0A3Q1N090", "name": "TAS2R60", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071230", "map_id": "ENSBTAT00000071230", "name": "TAS2R60", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MP17", "map_id": "F1MP17", "name": "LOC782957", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001761", "map_id": "ENSBTAT00000001761", "name": "LOC782957", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABB3", "map_id": "Q2ABB3", "name": "TAS2R46", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043009", "map_id": "ENSBTAT00000043009", "name": "TAS2R46", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRA2", "map_id": "A0A3Q1LRA2", "name": "TAS2R30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079249", "map_id": "ENSBTAT00000079249", "name": "TAS2R30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0Q7", "map_id": "A0A3Q1N0Q7", "name": "TAS2R7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082851", "map_id": "ENSBTAT00000082851", "name": "TAS2R7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZD2", "map_id": "F1MZD2", "name": "TAS2R38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033179", "map_id": "ENSBTAT00000033179", "name": "TAS2R38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ML22", "map_id": "A0A3Q1ML22", "name": "TAS2R13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071900", "map_id": "ENSBTAT00000071900", "name": "TAS2R13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2G6", "map_id": "F1N2G6", "name": "TAS2R42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043010", "map_id": "ENSBTAT00000043010", "name": "TAS2R42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABB1", "map_id": "Q2ABB1", "name": "T2R65A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031637", "map_id": "ENSBTAT00000031637", "name": "T2R65A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABC5", "map_id": "Q2ABC5", "name": "TAS2R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046105", "map_id": "ENSBTAT00000046105", "name": "TAS2R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8B7", "map_id": "E1B8B7", "name": "TAS2R40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055191", "map_id": "ENSBTAT00000055191", "name": "TAS2R40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABC4", "map_id": "Q2ABC4", "name": "TAS2R3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022454", "map_id": "ENSBTAT00000022454", "name": "TAS2R3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABC0", "map_id": "Q2ABC0", "name": "T2R10C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042999", "map_id": "ENSBTAT00000042999", "name": "T2R10C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZA1", "map_id": "A0A3Q1LZA1", "name": "TAS2R8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076866", "map_id": "ENSBTAT00000076866", "name": "TAS2R8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MIP5", "map_id": "A0A3Q1MIP5", "name": "TAS2R39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071184", "map_id": "ENSBTAT00000071184", "name": "TAS2R39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2ABC3", "map_id": "Q2ABC3", "name": "TAS2R4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024537", "map_id": "ENSBTAT00000024537", "name": "TAS2R4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3296423", "map_id": "none", "name": "Bitter-tasting compounds", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:3193", "map_id": "CHEBI:3193", "name": "CHEBI:3193", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_76328", "map_id": "CHEBI:28794", "name": "COUM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "CHEBI:3768", "map_id": "CHEBI:3768", "name": "CHEBI:3768", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:10093", "map_id": "CHEBI:10093", "name": "CHEBI:10093", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17814", "map_id": "CHEBI:17814", "name": "CHEBI:17814", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_40727", "map_id": "CHEBI:27732", "name": "CAF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "CHEBI:8206", "map_id": "CHEBI:8206", "name": "CHEBI:8206", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:48923", "map_id": "CHEBI:48923", "name": "CHEBI:48923", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28973", "map_id": "CHEBI:28973", "name": "CHEBI:28973", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73228", "map_id": "CHEBI:73228", "name": "CHEBI:73228", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:23359", "map_id": "CHEBI:23359", "name": "CHEBI:23359", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28241", "map_id": "CHEBI:28241", "name": "CHEBI:28241", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73226", "map_id": "CHEBI:73226", "name": "CHEBI:73226", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73224", "map_id": "CHEBI:73224", "name": "CHEBI:73224", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:65408", "map_id": "CHEBI:65408", "name": "CHEBI:65408", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:3944", "map_id": "CHEBI:3944", "name": "CHEBI:3944", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73235", "map_id": "CHEBI:73235", "name": "CHEBI:73235", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73231", "map_id": "CHEBI:73231", "name": "CHEBI:73231", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16226", "map_id": "CHEBI:16226", "name": "CHEBI:16226", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:27613", "map_id": "CHEBI:27613", "name": "CHEBI:27613", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:5547", "map_id": "CHEBI:5547", "name": "CHEBI:5547", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2825", "map_id": "CHEBI:2825", "name": "CHEBI:2825", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73232", "map_id": "CHEBI:73232", "name": "CHEBI:73232", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:18305", "map_id": "CHEBI:18305", "name": "CHEBI:18305", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:3445", "map_id": "CHEBI:3445", "name": "CHEBI:3445", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36773", "map_id": "CHEBI:36773", "name": "CHEBI:36773", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2622", "map_id": "CHEBI:2622", "name": "CHEBI:2622", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73237", "map_id": "CHEBI:73237", "name": "CHEBI:73237", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2366", "map_id": "CHEBI:2366", "name": "CHEBI:2366", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:3941", "map_id": "CHEBI:3941", "name": "CHEBI:3941", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:7939", "map_id": "CHEBI:7939", "name": "CHEBI:7939", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:351346", "map_id": "CHEBI:351346", "name": "CHEBI:351346", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:8692", "map_id": "CHEBI:8692", "name": "CHEBI:8692", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73239", "map_id": "CHEBI:73239", "name": "CHEBI:73239", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15854", "map_id": "CHEBI:15854", "name": "CHEBI:15854", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:9162", "map_id": "CHEBI:9162", "name": "CHEBI:9162", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:26948", "map_id": "CHEBI:26948", "name": "CHEBI:26948", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:50042", "map_id": "CHEBI:50042", "name": "CHEBI:50042", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:69236", "map_id": "CHEBI:69236", "name": "CHEBI:69236", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73222", "map_id": "CHEBI:73222", "name": "CHEBI:73222", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17698", "map_id": "CHEBI:17698", "name": "CHEBI:17698", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:73236", "map_id": "CHEBI:73236", "name": "CHEBI:73236", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2853", "map_id": "CHEBI:2853", "name": "CHEBI:2853", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046437", "map_id": "none", "name": "TAS2Rs:Bitter-tasting compounds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089211", "map_id": "none", "name": "Active G alpha (i)i1/i2/i3 binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039640", "map_id": "none", "name": "G alpha (i): GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3ZCA7", "map_id": "Q3ZCA7", "name": "GNAI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017303", "map_id": "ENSBTAT00000017303", "name": "GNAI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P63097", "map_id": "P63097", "name": "GNAI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003515", "map_id": "ENSBTAT00000003515", "name": "GNAI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBH9", "map_id": "A7MBH9", "name": "GNAI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027511", "map_id": "ENSBTAT00000027511", "name": "GNAI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G1K1V2", "map_id": "G1K1V2", "name": "GNAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023234", "map_id": "ENSBTAT00000023234", "name": "GNAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089193", "map_id": "none", "name": "RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O46471", "map_id": "O46471", "name": "RGS16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005642", "map_id": "ENSBTAT00000005642", "name": "RGS16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFC7", "map_id": "A0A3Q1MFC7", "name": "RGS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075674", "map_id": "ENSBTAT00000075674", "name": "RGS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7H3", "map_id": "E1B7H3", "name": "RGS8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037643", "map_id": "ENSBTAT00000037643", "name": "RGS8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMB5", "map_id": "E1BMB5", "name": "RGS18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048654", "map_id": "ENSBTAT00000048654", "name": "RGS18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBG6", "map_id": "A7MBG6", "name": "RGS17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012221", "map_id": "ENSBTAT00000012221", "name": "RGS17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMH1", "map_id": "F1MMH1", "name": "RGS11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022048", "map_id": "ENSBTAT00000022048", "name": "RGS11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUR0", "map_id": "F1MUR0", "name": "RGS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028880", "map_id": "ENSBTAT00000028880", "name": "RGS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7R3", "map_id": "F1N7R3", "name": "RGS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005904", "map_id": "ENSBTAT00000005904", "name": "RGS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79348", "map_id": "P79348", "name": "RGS20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004487", "map_id": "ENSBTAT00000004487", "name": "RGS20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIV2", "map_id": "E1BIV2", "name": "RGS14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011200", "map_id": "ENSBTAT00000011200", "name": "RGS14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N2W6", "map_id": "A0A3Q1N2W6", "name": "RGS13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070104", "map_id": "ENSBTAT00000070104", "name": "RGS13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BH23", "map_id": "E1BH23", "name": "RGS21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054620", "map_id": "ENSBTAT00000054620", "name": "RGS21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089209", "map_id": "none", "name": "G alpha (i):GTP:RGS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089197", "map_id": "none", "name": "G alpha (i):RGS dissociates to inactive G alpha (i)i1/i2/i3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089195", "map_id": "none", "name": "G alpha (i):GDP:RGS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10039660", "map_id": "none", "name": "G-protein alpha (i):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10088940", "map_id": "none", "name": "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10088932", "map_id": "none", "name": "G alpha (i):GTP:SRC-1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10088937", "map_id": "none", "name": "G protein alpha (i):GTP:p-Y416-SRC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10088942", "map_id": "none", "name": "G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10088935", "map_id": "E1BIM8", "name": "phospho-SRC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089214", "map_id": "none", "name": "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10048370", "map_id": "none", "name": "Opsins act as GEFs for G alpha-t", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048361", "map_id": "none", "name": "G-alpha(t):GDP:G-beta-gamma:Opsins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P63212", "map_id": "P63212", "name": "GNG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003959", "map_id": "ENSBTAT00000003959", "name": "GNG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04695", "map_id": "P04695", "name": "GNAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023990", "map_id": "ENSBTAT00000023990", "name": "GNAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048367", "map_id": "none", "name": "G-alpha(t):GTP:G-beta-gamma:Opsins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037037", "map_id": "none", "name": "PDE4A,C,D hydrolyse cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037034", "map_id": "none", "name": "PDE4A,C,D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N6Q5", "map_id": "A0A3Q1N6Q5", "name": "PDE4D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072751", "map_id": "ENSBTAT00000072751", "name": "PDE4D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5T6", "map_id": "F1N5T6", "name": "PDE4C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014100", "map_id": "ENSBTAT00000014100", "name": "PDE4C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039658", "map_id": "none", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039620", "map_id": "none", "name": "G alpha-olf:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M3D6", "map_id": "A0A3Q1M3D6", "name": "GNAL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079386", "map_id": "ENSBTAT00000079386", "name": "GNAL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039655", "map_id": "none", "name": "G alpha-olf:GTP:Adenylate cyclase (active) complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039674", "map_id": "none", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039669", "map_id": "none", "name": "G alpha-olf:GDP:Adenylate cyclase (active) complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039667", "map_id": "none", "name": "Adenylate cyclase converts ATP into cyclic AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10039671", "map_id": "none", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039646", "map_id": "none", "name": "G alpha-olf:GDP complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10036959", "map_id": "none", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114520", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10036956", "map_id": "none", "name": "Activated PLC beta 1/4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LVV4", "map_id": "A0A3Q1LVV4", "name": "PLCB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074229", "map_id": "ENSBTAT00000074229", "name": "PLCB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037045", "map_id": "none", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036942", "map_id": "A0A3Q1LVV4", "name": "PLCB2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039676", "map_id": "none", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039644", "map_id": "none", "name": "(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10039662", "map_id": "none", "name": "(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039664", "map_id": "none", "name": "Dissociation of the Gi alpha:G olf complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10039651", "map_id": "none", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039648", "map_id": "none", "name": "(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039653", "map_id": "none", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039642", "map_id": "none", "name": "G-protein alpha (i):GTP:Adenylate cyclase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046534", "map_id": "none", "name": "Liganded Gi-activating GPCR acts as a GEF for Gi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10046509", "map_id": "none", "name": "Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046513", "map_id": "none", "name": "Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046532", "map_id": "none", "name": "GPSM1, GPSM3,(GPSM2, PCP2)", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MMQ2", "map_id": "A0A3Q1MMQ2", "name": "GPSM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081300", "map_id": "ENSBTAT00000081300", "name": "GPSM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKT3", "map_id": "A0A3Q1MKT3", "name": "GPSM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078547", "map_id": "ENSBTAT00000078547", "name": "GPSM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089224", "map_id": "none", "name": "G alpha (q):RGS dissociates to inactive G alpha (q)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089219", "map_id": "none", "name": "G alpha (q):GDP:RGS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N3V3", "map_id": "F1N3V3", "name": "RGS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026460", "map_id": "ENSBTAT00000026460", "name": "RGS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089199", "map_id": "none", "name": "RGS1,2,3,4,5,13,16,17,18,19,21", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037355", "map_id": "none", "name": "G-protein alpha (q/11):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047979", "map_id": "none", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047977", "map_id": "none", "name": "RGS proteins active for G alpha (q)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048632", "map_id": "none", "name": "DAG activation of TRPC channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048628", "map_id": "none", "name": "TRPC3/6/7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M4W2", "map_id": "A0A3Q1M4W2", "name": "TRPC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077611", "map_id": "ENSBTAT00000077611", "name": "TRPC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTG6", "map_id": "A0A3Q1LTG6", "name": "TRPC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070979", "map_id": "ENSBTAT00000070979", "name": "TRPC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_114519", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048630", "map_id": "none", "name": "DAG-activated TRPC3/6/7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048543", "map_id": "none", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048539", "map_id": "none", "name": "Protein kinase C, novel isoforms", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MY82", "map_id": "F1MY82", "name": "PRKCH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004240", "map_id": "ENSBTAT00000004240", "name": "PRKCH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMG4", "map_id": "E1BMG4", "name": "PRKCQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060978", "map_id": "ENSBTAT00000060978", "name": "PRKCQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048541", "map_id": "none", "name": "Protein kinase C, novel isoforms:DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048587", "map_id": "none", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_422506", "map_id": "CHEBI:15843", "name": "AA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048584", "map_id": "A0A3Q1LUK0", "name": "MGLL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000073448", "map_id": "ENSBTAT00000073448", "name": "MGLL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048580", "map_id": "none", "name": "DAG is metabolized by DAGL to 2-AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_426026", "map_id": "CHEBI:35366", "name": "Fatty Acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048577", "map_id": "none", "name": "Diacylglycerol lipase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BBV2", "map_id": "E1BBV2", "name": "DAGLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018523", "map_id": "ENSBTAT00000018523", "name": "DAGLA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RA94", "map_id": "F6RA94", "name": "DAGLB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012173", "map_id": "ENSBTAT00000012173", "name": "DAGLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076743", "map_id": "none", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5694509", "map_id": "CHEBI:75571", "name": "3AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10076740", "map_id": "Q1LZ86", "name": "ABHD6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000022100", "map_id": "ENSBTAT00000022100", "name": "ABHD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048660", "map_id": "none", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048657", "map_id": "none", "name": "Diacylglycerol kinase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCG9", "map_id": "F1MCG9", "name": "DGKK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031198", "map_id": "ENSBTAT00000031198", "name": "DGKK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NJA6", "map_id": "A0A3Q1NJA6", "name": "DGKD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066461", "map_id": "ENSBTAT00000066461", "name": "DGKD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGA9", "map_id": "E1BGA9", "name": "DGKQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022905", "map_id": "ENSBTAT00000022905", "name": "DGKQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYT4", "map_id": "A0A3Q1LYT4", "name": "DGKG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075621", "map_id": "ENSBTAT00000075621", "name": "DGKG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N4W0", "map_id": "A0A3Q1N4W0", "name": "DGKI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080144", "map_id": "ENSBTAT00000080144", "name": "DGKI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037549", "map_id": "none", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037544", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):PIP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037546", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):DAG:IP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047823", "map_id": "none", "name": "G alpha (q) binds to Trio family RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047819", "map_id": "none", "name": "TRIO family RhoGEFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10047821", "map_id": "none", "name": "G-protein alpha (q/11):Trio family RhoGEFs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10064910", "map_id": "none", "name": "Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040201", "map_id": "A0A3Q1MHB0", "name": "EGFR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10064908", "map_id": "none", "name": "HB-EGF:p-6Y-EGFR dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10064915", "map_id": "none", "name": "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10064912", "map_id": "none", "name": "GRB2:SOS1:HB-EGF:p-6Y-EGFR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10064919", "map_id": "none", "name": "GRB2:SOS1 binds to HBEGF:p-Y-EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10089203", "map_id": "none", "name": "Active G alpha (q) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089201", "map_id": "none", "name": "G alpha (q):GTP:RGS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046149", "map_id": "none", "name": "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046140", "map_id": "none", "name": "Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "B5U8Y5", "map_id": "B5U8Y5", "name": "GHSR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014446", "map_id": "ENSBTAT00000014446", "name": "GHSR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9BDJ6", "map_id": "Q9BDJ6", "name": "GHRL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016350", "map_id": "ENSBTAT00000016350", "name": "GHRL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28716", "map_id": "CHEBI:28716", "name": "CHEBI:28716", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28875", "map_id": "CHEBI:28875", "name": "CHEBI:28875", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:53460", "map_id": "CHEBI:53460", "name": "CHEBI:53460", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:27997", "map_id": "CHEBI:27997", "name": "CHEBI:27997", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9024011", "map_id": "CHEBI:28125", "name": "DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:53487", "map_id": "CHEBI:53487", "name": "CHEBI:53487", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:53486", "map_id": "CHEBI:53486", "name": "CHEBI:53486", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8934421", "map_id": "CHEBI:9254", "name": "STEA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_9608444", "map_id": "CHEBI:53488", "name": "DPAn-3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:28661", "map_id": "CHEBI:28661", "name": "CHEBI:28661", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2026977", "map_id": "CHEBI:28364", "name": "EPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "E1BKC0", "map_id": "E1BKC0", "name": "FFAR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000560", "map_id": "ENSBTAT00000000560", "name": "FFAR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046142", "map_id": "none", "name": "Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046146", "map_id": "none", "name": "LTC4:CyslTR1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089222", "map_id": "none", "name": "G alpha (q) in G (q):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10047947", "map_id": "none", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047944", "map_id": "none", "name": "cAMP PDEs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MZ56", "map_id": "A0A3Q1MZ56", "name": "PDE2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078870", "map_id": "ENSBTAT00000078870", "name": "PDE2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MW13", "map_id": "A0A3Q1MW13", "name": "PDE10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079827", "map_id": "ENSBTAT00000079827", "name": "PDE10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPD8", "map_id": "E1BPD8", "name": "PDE11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021805", "map_id": "ENSBTAT00000021805", "name": "PDE11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3R2", "map_id": "A0A3Q1M3R2", "name": "PDE8A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085287", "map_id": "ENSBTAT00000085287", "name": "PDE8A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5L1", "map_id": "A0A3Q1M5L1", "name": "PDE8B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082666", "map_id": "ENSBTAT00000082666", "name": "PDE8B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089226", "map_id": "none", "name": "ADRB2:GRK complex dissociates to Phosphorylated ADRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083948", "map_id": "none", "name": "pS-ADRB2:Catecholamine:GRK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BP29", "map_id": "E1BP29", "name": "GRK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061163", "map_id": "ENSBTAT00000061163", "name": "GRK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083941", "map_id": "E1BP29", "name": "GRK6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084012", "map_id": "none", "name": "pS-ADRB2:Catecholamine", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089228", "map_id": "none", "name": "GRKs bind ADRB2:Catecholamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083943", "map_id": "none", "name": "ADRB2:Catecholamine:GRK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091247", "map_id": "none", "name": "PDE3A hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091244", "map_id": "A0A3Q1M1E8", "name": "PDE3A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072849", "map_id": "ENSBTAT00000072849", "name": "PDE3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083951", "map_id": "none", "name": "ADRB2 in ADRB2:GRK complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10084016", "map_id": "none", "name": "ADRB2:Catecholamine binds ARRB1, ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047876", "map_id": "G3X811", "name": "ARRB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000050078", "map_id": "ENSBTAT00000050078", "name": "ARRB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084014", "map_id": "none", "name": "pS-ADRB2:Catecholamine:ARRB1,ARRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3X811", "map_id": "G3X811", "name": "ARRB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092055", "map_id": "none", "name": "PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092052", "map_id": "E1BN64", "name": "PDE3B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10047498", "map_id": "none", "name": "G beta:gamma activated PI3Kgamma converts PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047495", "map_id": "none", "name": "G-protein beta-gamma:PI3K gamma", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M2L5", "map_id": "A0A3Q1M2L5", "name": "PIK3CG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080364", "map_id": "ENSBTAT00000080364", "name": "PIK3CG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCV1", "map_id": "E1BCV1", "name": "PIK3R5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007845", "map_id": "ENSBTAT00000007845", "name": "PIK3R5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043315", "map_id": "none", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037311", "map_id": "P61585", "name": "RHOA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10043313", "map_id": "none", "name": "PIP3:RhoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10088962", "map_id": "none", "name": "PAK1 binds ARHGEF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047596", "map_id": "Q08E52", "name": "PAK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048105", "map_id": "A0A3Q1LKT5", "name": "ARHGEF6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083031", "map_id": "ENSBTAT00000083031", "name": "ARHGEF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088960", "map_id": "none", "name": "PAK1:ARHGEF6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LKT5", "map_id": "A0A3Q1LKT5", "name": "ARHGEF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051656", "map_id": "none", "name": "Liganded Gz-activating GPCR acts as a GEF for Gz", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051649", "map_id": "none", "name": "Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MM27", "map_id": "A0A3Q1MM27", "name": "GNAZ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074311", "map_id": "ENSBTAT00000074311", "name": "GNAZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051653", "map_id": "none", "name": "ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047468", "map_id": "none", "name": "G alpha (z) inhibits adenylate cyclase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047464", "map_id": "none", "name": "G-protein alpha (z):GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047466", "map_id": "none", "name": "G-protein alpha (z):GTP:Adenylate cyclase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089167", "map_id": "none", "name": "Active G alpha (z) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089163", "map_id": "none", "name": "RGS16,17,20", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089165", "map_id": "none", "name": "G alpha (z):GTP:RGS16,17,20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089217", "map_id": "none", "name": "G alpha (z) in G alpha (z):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089205", "map_id": "none", "name": "G alpha (z):GDP:RGS16,17,20", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089207", "map_id": "none", "name": "G alpha (z):RGS complex dissociates to give inactive G alpha (z)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051645", "map_id": "none", "name": "G-protein alpha (z):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048170", "map_id": "none", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047839", "map_id": "none", "name": "RhoA,B,C:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047841", "map_id": "none", "name": "RHOA/B/C:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10048167", "map_id": "none", "name": "GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B9G8", "map_id": "E1B9G8", "name": "ARHGEF18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014311", "map_id": "ENSBTAT00000014311", "name": "ARHGEF18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MA97", "map_id": "A0A3Q1MA97", "name": "ARHGEF16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081198", "map_id": "ENSBTAT00000081198", "name": "ARHGEF16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LXW7", "map_id": "A0A3Q1LXW7", "name": "TIAM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081961", "map_id": "ENSBTAT00000081961", "name": "TIAM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MA22", "map_id": "A0A3Q1MA22", "name": "ARHGEF9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069238", "map_id": "ENSBTAT00000069238", "name": "ARHGEF9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E6P3", "map_id": "G5E6P3", "name": "GNA13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000062941", "map_id": "ENSBTAT00000062941", "name": "GNA13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58CS5", "map_id": "Q58CS5", "name": "FGD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009131", "map_id": "ENSBTAT00000009131", "name": "FGD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N5H1", "map_id": "A0A3Q1N5H1", "name": "FGD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068004", "map_id": "ENSBTAT00000068004", "name": "FGD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047552", "map_id": "none", "name": "LARG activation by G alpha 12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047548", "map_id": "A0A3Q1MN47", "name": "ARHGEF12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047544", "map_id": "none", "name": "G-protein alpha (12/13):GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BIL1", "map_id": "E1BIL1", "name": "GNA12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023757", "map_id": "ENSBTAT00000023757", "name": "GNA12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047550", "map_id": "none", "name": "G-protein alpha (12/13):LARG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051667", "map_id": "none", "name": "Liganded G12/13-activating GPCR acts as a GEF for G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051664", "map_id": "none", "name": "Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive).", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051660", "map_id": "none", "name": "Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active).", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037330", "map_id": "none", "name": "p115-RhoGEF activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037327", "map_id": "none", "name": "G13-activated p115-RhoGEF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037332", "map_id": "none", "name": "G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037325", "map_id": "A0A3Q1LFQ5", "name": "ARHGEF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037321", "map_id": "none", "name": "G-protein alpha (13):GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047956", "map_id": "none", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047953", "map_id": "none", "name": "G-protein alpha (12/13):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072123", "map_id": "none", "name": "KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263228", "compartment_display": "ciliary tip" }, { "id": "species_10072119", "map_id": "A0A3Q1LM07", "name": "KIF7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5263228", "compartment_display": "ciliary tip", "complex": "false" }, { "id": "ENSBTAT00000075908", "map_id": "ENSBTAT00000075908", "name": "KIF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072115", "map_id": "none", "name": "microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_18728", "compartment_display": "axonemal microtubule", "complex": "true" }, { "id": "species_10072121", "map_id": "none", "name": "KIF7:microtubule", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263228", "compartment_display": "ciliary tip", "complex": "true" }, { "id": "A0A3Q1LM07", "map_id": "A0A3Q1LM07", "name": "KIF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072154", "map_id": "none", "name": "PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane" }, { "id": "species_10072144", "map_id": "none", "name": "SMO dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "E1BE57", "map_id": "E1BE57", "name": "SMO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017670", "map_id": "ENSBTAT00000017670", "name": "SMO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072148", "map_id": "none", "name": "SMO dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263228", "compartment_display": "ciliary tip", "complex": "true" }, { "id": "species_10072152", "map_id": "G3N1D5", "name": "PTCH1", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_261122", "compartment_display": "ciliary membrane", "complex": "false" }, { "id": "ENSBTAT00000064817", "map_id": "ENSBTAT00000064817", "name": "PTCH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072220", "map_id": "none", "name": "The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263228", "compartment_display": "ciliary tip" }, { "id": "species_10072079", "map_id": "none", "name": "GLI:SUFU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6H727", "map_id": "A6H727", "name": "GLI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008704", "map_id": "ENSBTAT00000008704", "name": "GLI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCY1", "map_id": "F1MCY1", "name": "phospho-GLI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015510", "map_id": "ENSBTAT00000015510", "name": "phospho-GLI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDV1", "map_id": "A0A3Q1MDV1", "name": "SUFU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068810", "map_id": "ENSBTAT00000068810", "name": "SUFU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072165", "map_id": "none", "name": "GLI:SUFU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263228", "compartment_display": "ciliary tip", "complex": "true" }, { "id": "species_10072218", "map_id": "none", "name": "anterograde IFT regulators of Hh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_18730", "compartment_display": "cilium", "complex": "true" }, { "id": "E1BKE3", "map_id": "E1BKE3", "name": "KIF3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035821", "map_id": "ENSBTAT00000035821", "name": "KIF3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MNB3", "map_id": "A0A3Q1MNB3", "name": "IFT88", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078675", "map_id": "ENSBTAT00000078675", "name": "IFT88", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32KR5", "map_id": "Q32KR5", "name": "IFT52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087155", "map_id": "ENSBTAT00000087155", "name": "IFT52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIR3", "map_id": "A0A452DIR3", "name": "IFT57", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007606", "map_id": "ENSBTAT00000007606", "name": "IFT57", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072197", "map_id": "none", "name": "PCP regulators of Hh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BBF8", "map_id": "E1BBF8", "name": "FUZ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025532", "map_id": "ENSBTAT00000025532", "name": "FUZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDL2", "map_id": "F1MDL2", "name": "INTU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017038", "map_id": "ENSBTAT00000017038", "name": "INTU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072183", "map_id": "none", "name": "ciliary basal body regulators of Hh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6RVK1", "map_id": "F6RVK1", "name": "MKS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049437", "map_id": "ENSBTAT00000049437", "name": "MKS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTC8", "map_id": "A0A3Q1LTC8", "name": "OFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082308", "map_id": "ENSBTAT00000082308", "name": "OFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072081", "map_id": "none", "name": "GLI proteins bind SUFU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072077", "map_id": "A0A3Q1MDV1", "name": "SUFU", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072073", "map_id": "none", "name": "GLI1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072138", "map_id": "none", "name": "SCF(beta-TrCP) ubiquitinates p-GLI1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263232", "compartment_display": "ciliary base" }, { "id": "species_10072130", "map_id": "none", "name": "pS-GLI1:SUFU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10072135", "map_id": "none", "name": "ub-pS-GLI1:SUFU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "reaction_10072199", "map_id": "none", "name": "The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263232", "compartment_display": "ciliary base" }, { "id": "species_10072173", "map_id": "none", "name": "GLI:SUFU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10072187", "map_id": "F1MG59", "name": "IFT122", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_18730", "compartment_display": "cilium", "complex": "false" }, { "id": "ENSBTAT00000036487", "map_id": "ENSBTAT00000036487", "name": "IFT122", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072713", "map_id": "none", "name": "SPOP:CUL3:RBX1 ubiquitinates GLI2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072710", "map_id": "none", "name": "2p-GLI:SPOP:CUL3:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0VCW1", "map_id": "Q0VCW1", "name": "SPOP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007660", "map_id": "ENSBTAT00000007660", "name": "SPOP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072708", "map_id": "none", "name": "ub-2p-GLI2,3:SPOP:CUL3:RBX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10072715", "map_id": "none", "name": "GLI:SUFU translocates to the ciliary tip in response to Hh signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263228", "compartment_display": "ciliary tip" }, { "id": "reaction_10072685", "map_id": "none", "name": "GLI proteins bind CDC73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072669", "map_id": "none", "name": "2p-GLI1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10072681", "map_id": "E1BPQ8", "name": "CDC73", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000022205", "map_id": "ENSBTAT00000022205", "name": "CDC73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072683", "map_id": "none", "name": "CDC73:2p-GLI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BPQ8", "map_id": "E1BPQ8", "name": "CDC73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072606", "map_id": "none", "name": "PTCH is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_261122", "compartment_display": "ciliary membrane" }, { "id": "species_10072602", "map_id": "G3N1D5", "name": "PTCH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_261122", "compartment_display": "ciliary membrane", "complex": "false" }, { "id": "species_10072604", "map_id": "G3N1D5", "name": "PTCH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "false" }, { "id": "reaction_10072720", "map_id": "none", "name": "SMURF1/2 dissociates from ub-PTCH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_261122", "compartment_display": "ciliary membrane" }, { "id": "species_10072718", "map_id": "none", "name": "ub-PTCH1:SMURF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_261122", "compartment_display": "ciliary membrane", "complex": "true" }, { "id": "G3N1D5", "map_id": "G3N1D5", "name": "PTCH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072677", "map_id": "none", "name": "GLI translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263228", "compartment_display": "ciliary tip" }, { "id": "species_10072675", "map_id": "none", "name": "p-GLI1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263228", "compartment_display": "ciliary tip", "complex": "true" }, { "id": "species_10072663", "map_id": "none", "name": "p-GLI1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074038", "map_id": "none", "name": "RAS GEFs promote RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074035", "map_id": "none", "name": "RAS GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LI10", "map_id": "A0A3Q1LI10", "name": "PTPRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073047", "map_id": "ENSBTAT00000073047", "name": "PTPRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMN5", "map_id": "E1BMN5", "name": "SPTBN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007787", "map_id": "ENSBTAT00000007787", "name": "SPTBN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKE9", "map_id": "F1MKE9", "name": "SPTB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006213", "map_id": "ENSBTAT00000006213", "name": "SPTB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMQ8", "map_id": "F1MMQ8", "name": "SPTA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061417", "map_id": "ENSBTAT00000061417", "name": "SPTA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNC8", "map_id": "A0A3Q1LNC8", "name": "SPTAN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066559", "map_id": "ENSBTAT00000066559", "name": "SPTAN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJB1", "map_id": "A0A452DJB1", "name": "RASGRP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044847", "map_id": "ENSBTAT00000044847", "name": "RASGRP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHX3", "map_id": "A0A452DHX3", "name": "KIT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003498", "map_id": "ENSBTAT00000003498", "name": "KIT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5N3", "map_id": "F1N5N3", "name": "phospho-SHC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021391", "map_id": "ENSBTAT00000021391", "name": "phospho-SHC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MP52", "map_id": "F1MP52", "name": "SHC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015112", "map_id": "ENSBTAT00000015112", "name": "SHC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6S0Q2", "map_id": "F6S0Q2", "name": "GDNF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006816", "map_id": "ENSBTAT00000006816", "name": "GDNF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKU1", "map_id": "E1BKU1", "name": "NRTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000528", "map_id": "ENSBTAT00000000528", "name": "NRTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MS00", "map_id": "F1MS00", "name": "RET", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000744", "map_id": "ENSBTAT00000000744", "name": "RET", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N8H3", "map_id": "A0A3Q1N8H3", "name": "GFRA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083411", "map_id": "ENSBTAT00000083411", "name": "GFRA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0Y1", "map_id": "A0A3Q1M0Y1", "name": "GFRA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081398", "map_id": "ENSBTAT00000081398", "name": "GFRA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD76", "map_id": "E1BD76", "name": "ARTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023553", "map_id": "ENSBTAT00000023553", "name": "ARTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCL0", "map_id": "E1BCL0", "name": "PSPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027984", "map_id": "ENSBTAT00000027984", "name": "PSPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZM3", "map_id": "G3MZM3", "name": "GFRA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066172", "map_id": "ENSBTAT00000066172", "name": "GFRA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSU3", "map_id": "A0A3Q1LSU3", "name": "phospho-RASGRP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068365", "map_id": "ENSBTAT00000068365", "name": "phospho-RASGRP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N010", "map_id": "A0A3Q1N010", "name": "RASGEF1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084300", "map_id": "ENSBTAT00000084300", "name": "RASGEF1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091515", "map_id": "none", "name": "RAS proteins are depalmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039726", "map_id": "none", "name": "mature p21 RAS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_8848337", "map_id": "CHEBI:7896", "name": "PALM(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091512", "map_id": "none", "name": "S-Farn-Me KRAS4A, HRAS, NRAS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091502", "map_id": "none", "name": "LYPLA1 dimer, ABHD17A,B,C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M5Z8", "map_id": "A0A3Q1M5Z8", "name": "LYPLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081950", "map_id": "ENSBTAT00000081950", "name": "LYPLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBG2", "map_id": "A7MBG2", "name": "ABHD17B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008957", "map_id": "ENSBTAT00000008957", "name": "ABHD17B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091504", "map_id": "none", "name": "Palmostatin B:LYPLA1 dimer, ABHD17A,B,C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091458", "map_id": "none", "name": "ICMT methylates S-Farn RAS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10091448", "map_id": "none", "name": "S-Farn-RAS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10091454", "map_id": "none", "name": "S-Farn-Me RAS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10077880", "map_id": "none", "name": "ICMT:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G3N1V4", "map_id": "G3N1V4", "name": "ICMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064297", "map_id": "ENSBTAT00000064297", "name": "ICMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091456", "map_id": "none", "name": "ICMT:Zn2+:Cysmethynil", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10091490", "map_id": "none", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10091477", "map_id": "none", "name": "S-Farn-Me PalmS KRAS4A,HRAS, NRAS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10091487", "map_id": "none", "name": "ZDHHC9:GOLGA7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q5EA55", "map_id": "Q5EA55", "name": "GOLGA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069302", "map_id": "ENSBTAT00000069302", "name": "GOLGA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DA8", "map_id": "Q58DA8", "name": "ZDHHC9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075844", "map_id": "ENSBTAT00000075844", "name": "ZDHHC9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091506", "map_id": "none", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9647934", "map_id": "none", "name": "Palmostatin B", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091479", "map_id": "none", "name": "mature RAS proteins translocate to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091527", "map_id": "none", "name": "mature p21 RAS binds GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10074088", "map_id": "none", "name": "Phosphorylation of RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074042", "map_id": "none", "name": "p21 RAS:GTP:homo/heterodimerized RAF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A452DI16", "map_id": "A0A452DI16", "name": "phospho-ARAF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006653", "map_id": "ENSBTAT00000006653", "name": "phospho-ARAF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQP3", "map_id": "A0A3Q1LQP3", "name": "phospho-KSR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074936", "map_id": "ENSBTAT00000074936", "name": "phospho-KSR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M888", "map_id": "A0A3Q1M888", "name": "MARK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079194", "map_id": "ENSBTAT00000079194", "name": "MARK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M353", "map_id": "A0A3Q1M353", "name": "BRAF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086962", "map_id": "ENSBTAT00000086962", "name": "BRAF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074065", "map_id": "none", "name": "p21 RAS:GTP:activated RAF homo/heterodimer complexes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074085", "map_id": "none", "name": "RAF activating kinases", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10073930", "map_id": "none", "name": "PP2A dephosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073919", "map_id": "none", "name": "p-S311,S406 KSR1:MARK3:YWHAB dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073927", "map_id": "none", "name": "p-S311 KSR1:MARK3:YWHAB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073917", "map_id": "none", "name": "Inactive RAFs bind YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073913", "map_id": "none", "name": "inactive RAFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073915", "map_id": "none", "name": "inactive RAFs:YWHAB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073932", "map_id": "none", "name": "YWHAB dimer dissociates from KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073925", "map_id": "none", "name": "p-S311 KSR1:MARK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091548", "map_id": "none", "name": "Raf dimer inhibitors bind RAF heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9657579", "map_id": "none", "name": "RAF dimer inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10074135", "map_id": "none", "name": "p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073921", "map_id": "none", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073869", "map_id": "none", "name": "p-S311,S406 KSR1:MARK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073904", "map_id": "none", "name": "\"Activator\" RAF:YWHAB dimer binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073896", "map_id": "none", "name": "'activator' RAF:YWHAB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073898", "map_id": "none", "name": "p21 RAS:GTP:'activator' RAF:YWHAB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073902", "map_id": "Q3T165", "name": "PHB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070853", "map_id": "ENSBTAT00000070853", "name": "PHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073872", "map_id": "none", "name": "MARK3 phosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073863", "map_id": "none", "name": "KSR1:MARK3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10074050", "map_id": "none", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074040", "map_id": "none", "name": "dephosphorylated \"receiver\" RAF/KSR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10074048", "map_id": "none", "name": "BRAP:KSR1:MARK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6H716", "map_id": "A6H716", "name": "BRAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001552", "map_id": "ENSBTAT00000001552", "name": "BRAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073940", "map_id": "none", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073938", "map_id": "none", "name": "dephosphorylated inactive RAFS:YWHAB dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073936", "map_id": "none", "name": "dephosphorylated inactive RAFs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073942", "map_id": "none", "name": "PP2A dephosphorylates inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10074184", "map_id": "none", "name": "PAQR3 binds inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10074180", "map_id": "A0A3Q1M5M4", "name": "PAQR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000071243", "map_id": "ENSBTAT00000071243", "name": "PAQR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074182", "map_id": "none", "name": "PAQR3:inactive RAFs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1M5M4", "map_id": "A0A3Q1M5M4", "name": "PAQR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074221", "map_id": "none", "name": "PEBP1 binds activated RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074213", "map_id": "none", "name": "p21RAS:GTP:activated RAF1 homo/heterodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074217", "map_id": "P13696", "name": "PEBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024107", "map_id": "ENSBTAT00000024107", "name": "PEBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074219", "map_id": "none", "name": "p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P13696", "map_id": "P13696", "name": "PEBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074156", "map_id": "none", "name": "BRAP autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074144", "map_id": "none", "name": "p21 RAS:GTP:BRAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074153", "map_id": "none", "name": "p21 RAS:GTP:ub-BRAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074238", "map_id": "none", "name": "PP5 dephosphorylates RAF1 S338", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074225", "map_id": "none", "name": "p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074235", "map_id": "F1N719", "name": "PPP5C", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010538", "map_id": "ENSBTAT00000010538", "name": "PPP5C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074146", "map_id": "none", "name": "BRAP binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074046", "map_id": "A6H716", "name": "BRAP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10074148", "map_id": "none", "name": "BRAP binds KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10074231", "map_id": "none", "name": "PP2A dephosphorylates RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074229", "map_id": "none", "name": "p21RAS:GTP:p-S621 RAF1 homo/heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091534", "map_id": "none", "name": "RAS intrinsic GTPase activity hydrolyzes GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091580", "map_id": "none", "name": "RAS:GTP binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091578", "map_id": "none", "name": "p21 RAS:GTP:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074137", "map_id": "none", "name": "RAF phosphorylates MAP2K dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074123", "map_id": "none", "name": "activated RAF:scaffold:MAP2K:MAPK complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0VD16", "map_id": "Q0VD16", "name": "MAP2K1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048212", "map_id": "ENSBTAT00000048212", "name": "MAP2K1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPX3", "map_id": "A0A3S5ZPX3", "name": "MAP2K2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011377", "map_id": "ENSBTAT00000011377", "name": "MAP2K2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074114", "map_id": "none", "name": "activated RAF:scaffold:p-2S MAP2K:MAPK complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074125", "map_id": "none", "name": "activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091576", "map_id": "none", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074118", "map_id": "none", "name": "activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_9657577", "map_id": "none", "name": "single mechanism MAPK inhibitors", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091574", "map_id": "none", "name": "activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074129", "map_id": "none", "name": "MAP2Ks phosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074127", "map_id": "none", "name": "activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074121", "map_id": "none", "name": "activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091568", "map_id": "none", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9657567", "map_id": "none", "name": "dual mechanism MAP2K1/2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10074176", "map_id": "none", "name": "MAP2Ks and MAPKs are phosphorylated at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10074172", "map_id": "none", "name": "WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "Q0VCN2", "map_id": "Q0VCN2", "name": "WDR83", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082130", "map_id": "ENSBTAT00000082130", "name": "WDR83", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074174", "map_id": "none", "name": "WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10074195", "map_id": "none", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10074190", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:MAPKs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BP15", "map_id": "E1BP15", "name": "IL17RD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060984", "map_id": "ENSBTAT00000060984", "name": "IL17RD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074192", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:p-T,Y MAPKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10091570", "map_id": "none", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9657570", "map_id": "none", "name": "dual mechanism MAPK inhibitors", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091572", "map_id": "none", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9657574", "map_id": "none", "name": "single mechanism MAP2K1/2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091595", "map_id": "none", "name": "RAS:GTP binds RAL GDS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091591", "map_id": "none", "name": "S-Farn-Me-2xPalmS HRAS:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091589", "map_id": "none", "name": "RAL GDS proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NAC7", "map_id": "A0A3Q1NAC7", "name": "RGL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076160", "map_id": "ENSBTAT00000076160", "name": "RGL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6Z6", "map_id": "A0A3Q1M6Z6", "name": "RALGDS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087412", "map_id": "ENSBTAT00000087412", "name": "RALGDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091593", "map_id": "none", "name": "S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091529", "map_id": "none", "name": "Intrinsic nucleotide exchange on RAS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10075256", "map_id": "none", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075220", "map_id": "none", "name": "p-S MAPK6,4:p-T182 MAKPAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MVV5", "map_id": "F1MVV5", "name": "MAPK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013073", "map_id": "ENSBTAT00000013073", "name": "MAPK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E577", "map_id": "G5E577", "name": "MAPK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007709", "map_id": "ENSBTAT00000007709", "name": "MAPK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MH23", "map_id": "F1MH23", "name": "phospho-MAPKAPK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012303", "map_id": "ENSBTAT00000012303", "name": "phospho-MAPKAPK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075236", "map_id": "F1MH23", "name": "phospho-MAPKAPK5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075202", "map_id": "none", "name": "p-S MAPK6,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075260", "map_id": "none", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075208", "map_id": "F1MH23", "name": "phospho-MAPKAPK5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10075258", "map_id": "F1MH23", "name": "phospho-MAPKAPK5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10075262", "map_id": "none", "name": "p-S215 FOXO3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075234", "map_id": "F1N4K5", "name": "phospho-FOXO3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075226", "map_id": "F1N4K5", "name": "phospho-FOXO3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10075251", "map_id": "none", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075241", "map_id": "none", "name": "MAPK4,6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075249", "map_id": "none", "name": "MAPK4,6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075218", "map_id": "none", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066851", "map_id": "F1MH23", "name": "MAPKAPK5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10075214", "map_id": "none", "name": "p-S MAPK6,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075216", "map_id": "none", "name": "p-S MAPK6,4:MAKPAPK5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075253", "map_id": "none", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10075223", "map_id": "none", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10075916", "map_id": "none", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075904", "map_id": "none", "name": "p-T182 MAPKAPK5:DNAJB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3MI00", "map_id": "Q3MI00", "name": "DNAJB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036270", "map_id": "ENSBTAT00000036270", "name": "DNAJB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075913", "map_id": "none", "name": "p-T182 MAPKAPK5:p-S149,S151, S171 DNAJB1 ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076193", "map_id": "none", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076189", "map_id": "A0A3Q1MTC5", "name": "CDC14B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000075652", "map_id": "ENSBTAT00000075652", "name": "CDC14B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076185", "map_id": "G5E577", "name": "phospho-MAPK6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10076191", "map_id": "none", "name": "p-3S,T MAPK6:CDC14A,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MTC5", "map_id": "A0A3Q1MTC5", "name": "CDC14B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075906", "map_id": "none", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067944", "map_id": "Q3MI00", "name": "DNAJB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10075205", "map_id": "none", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075194", "map_id": "none", "name": "MAPK6,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10047654", "map_id": "none", "name": "p-S,T-PAK1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M0G8", "map_id": "A0A3Q1M0G8", "name": "PAK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082239", "map_id": "ENSBTAT00000082239", "name": "PAK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSY0", "map_id": "A0A3Q1LSY0", "name": "PAK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085260", "map_id": "ENSBTAT00000085260", "name": "PAK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076229", "map_id": "none", "name": "p-S182 MAPKAPK5 phosphorylates FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10042661", "map_id": "A0A452DJI7", "name": "FOXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000061127", "map_id": "ENSBTAT00000061127", "name": "FOXO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076226", "map_id": "A0A452DJI7", "name": "phospho-FOXO1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066865", "map_id": "F1MH23", "name": "phospho-MAPKAPK5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10075239", "map_id": "none", "name": "p-T182 MAPKAPK5 phosphorylates FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075232", "map_id": "F1N4K5", "name": "FOXO3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10076198", "map_id": "none", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076195", "map_id": "none", "name": "MAPK6:CDC14A,B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10039690", "map_id": "none", "name": "FRS2 binds to active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10039686", "map_id": "E1B7I9", "name": "FRS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039688", "map_id": "none", "name": "Active TrkA receptor:FRS2 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10090954", "map_id": "none", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10090951", "map_id": "none", "name": "RAP1:GTP:B-Raf complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10090933", "map_id": "none", "name": "RAP1:GTP:activated BRAF dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10039711", "map_id": "none", "name": "p-FRS2:CRKL binds C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10039703", "map_id": "none", "name": "Active TrkA receptor:p-FRS2:CRKL complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10039709", "map_id": "none", "name": "Active TrkA receptor:p-FRS2:CRKL:RAPGEF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10039697", "map_id": "none", "name": "FRS2 is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10039694", "map_id": "none", "name": "Active TrkA receptor:p-FRS2 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10090944", "map_id": "none", "name": "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10090935", "map_id": "none", "name": "RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10090937", "map_id": "none", "name": "RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10090949", "map_id": "none", "name": "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090946", "map_id": "none", "name": "RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10039592", "map_id": "none", "name": "C3G stimulates nucleotide exchange on Rap1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039587", "map_id": "none", "name": "Rap1-GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039589", "map_id": "none", "name": "Rap1-GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039579", "map_id": "none", "name": "Active TrkA receptor:Phospho-ARMS:Crk complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039581", "map_id": "none", "name": "Crk's SH3 domain engages C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10039601", "map_id": "none", "name": "ARMS is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039598", "map_id": "none", "name": "Active TrkA receptor:ARMS:Crk complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074879", "map_id": "none", "name": "GRB2-1:SOS1 binds p-Y-SHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073958", "map_id": "none", "name": "p-Y-SHC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073960", "map_id": "none", "name": "GRB2-1:SOS1:p-Y-SHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10039736", "map_id": "none", "name": "Ral-GDS binds to Ras-GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039732", "map_id": "A0A3Q1M6Z6", "name": "RALGDS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039734", "map_id": "none", "name": "Ras-GTP:RalGDS complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040570", "map_id": "none", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040546", "map_id": "A0A3Q1M614", "name": "MAPKAPK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040551", "map_id": "A0A3Q1M614", "name": "phospho-MAPKAPK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040567", "map_id": "none", "name": "Phospho-MAP kinase p38 (Mg2+ cofactor)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090994", "map_id": "none", "name": "NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090982", "map_id": "Q1RMU0", "name": "NAB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000008295", "map_id": "ENSBTAT00000008295", "name": "NAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090978", "map_id": "F1N3F6", "name": "CHD4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000019612", "map_id": "ENSBTAT00000019612", "name": "CHD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090990", "map_id": "none", "name": "RRAD gene:EGR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3N0C9", "map_id": "G3N0C9", "name": "EGR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064240", "map_id": "ENSBTAT00000064240", "name": "EGR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090992", "map_id": "none", "name": "RRAD gene:EGR2:NAB2:CHD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N3F6", "map_id": "F1N3F6", "name": "CHD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMU0", "map_id": "Q1RMU0", "name": "NAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041851", "map_id": "none", "name": "PI3K produces PIP3 and other phosphatidyl inositides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10041848", "map_id": "none", "name": "Phospho-IRS1/2:PI3K(p85:p110)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10041869", "map_id": "none", "name": "Active IRS recruits PI3K to the plasma membrane and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10041865", "map_id": "none", "name": "Activated TrkA receptor:Phospho-IRS1/2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10041867", "map_id": "none", "name": "Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10041917", "map_id": "none", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10041913", "map_id": "A5PKJ4", "name": "phospho-MAPK7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041915", "map_id": "A5PKJ4", "name": "phospho-MAPK7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10040489", "map_id": "none", "name": "Part of pro-beta-NGF is processed to mature beta-NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10040476", "map_id": "none", "name": "pro-beta-NGF homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10040480", "map_id": "none", "name": "mature beta-NGF homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10040486", "map_id": "none", "name": "Subtilisin/kexin convertase (Calcium dependant)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "A0A3Q1MCD7", "map_id": "A0A3Q1MCD7", "name": "PCSK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077745", "map_id": "ENSBTAT00000077745", "name": "PCSK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040495", "map_id": "none", "name": "Pro-beta-NGF and mature beta-NGF are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040493", "map_id": "none", "name": "pro-beta-NGF homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090722", "map_id": "none", "name": "Activated NTRK3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090663", "map_id": "none", "name": "NTF3:p-5Y-NTRK3 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q08DT3", "map_id": "Q08DT3", "name": "NTF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013493", "map_id": "ENSBTAT00000013493", "name": "NTF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090411", "map_id": "E1BIM8", "name": "SRC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10090720", "map_id": "none", "name": "NTF3:p-5Y-NTKR3 homodimer:MyrG-SRC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090727", "map_id": "none", "name": "Activated NTRK3 promotes SRC autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090724", "map_id": "none", "name": "NTF3:p-5Y-NTRK3 homodimer:MyrG-p-Y419-SRC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090666", "map_id": "none", "name": "NTRK3 dimers trans-autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090654", "map_id": "none", "name": "NTF3:NTRK3 homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090675", "map_id": "none", "name": "Activated PCLG1 dissociates from NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090673", "map_id": "none", "name": "NTF3:p-5Y-NTRK3 homodimer:p-4Y-PLCG1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073244", "map_id": "none", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040423", "map_id": "none", "name": "p-Y371-CBL:GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073210", "map_id": "none", "name": "Activated FGFR3:p-FRS2:p-PTPN11:p-CBL:GRB2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073215", "map_id": "none", "name": "CBL ubiquitinates FRS2 and FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073212", "map_id": "none", "name": "Ub-Activated FGFR3 complex:Ub-p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057337", "map_id": "none", "name": "PPA2A dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057334", "map_id": "none", "name": "PPA2A (A:C):S112/S115 p-SPRY2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08E39", "map_id": "Q08E39", "name": "phospho-SPRY2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002324", "map_id": "ENSBTAT00000002324", "name": "phospho-SPRY2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJ84", "map_id": "A0A3Q1MJ84", "name": "PPP2R1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079589", "map_id": "ENSBTAT00000079589", "name": "PPP2R1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJY7", "map_id": "A0A3Q1MJY7", "name": "PPP2R1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0P594", "map_id": "Q0P594", "name": "PPP2CB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012182", "map_id": "ENSBTAT00000012182", "name": "PPP2CB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P67774", "map_id": "P67774", "name": "PPP2CA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000596", "map_id": "ENSBTAT00000000596", "name": "PPP2CA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057300", "map_id": "none", "name": "PPA2A(A:C):SPRY2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10057323", "map_id": "none", "name": "SPRY2 binds GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057316", "map_id": "none", "name": "PP2A(A:C):Y55/Y227-pSPRY2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057321", "map_id": "none", "name": "PPA2A (A:C):Y55/Y227 p-SPRY2:GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10053082", "map_id": "none", "name": "Phosphorylated SPRY2 is ubiquitinated by CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053077", "map_id": "none", "name": "Y55/Y227-pSPRY2:CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10053079", "map_id": "none", "name": "Ub:Y55/Y227-pSPRY2:CBL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057327", "map_id": "none", "name": "CBL dissociates from ubiquitinated p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057325", "map_id": "none", "name": "Ub-(Y55/Y227)p-SPRY2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057329", "map_id": "none", "name": "SPRY2 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053062", "map_id": "none", "name": "PP2A (A:C)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10057314", "map_id": "none", "name": "B-RAF dissociates from S111/S120 p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057312", "map_id": "none", "name": "S111/S120 p-SPRY2:B-RAF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10057310", "map_id": "A0A3Q1M353", "name": "BRAF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057306", "map_id": "Q08E39", "name": "phospho-SPRY2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10059156", "map_id": "none", "name": "PPTN11 dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10057302", "map_id": "none", "name": "SPRY2 translocates to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053066", "map_id": "none", "name": "PP2A(A:C):SPRY2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057318", "map_id": "none", "name": "SRC phosphorylates SPRY2 on Y55 and Y227", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040307", "map_id": "E1BIM8", "name": "SRC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10053072", "map_id": "none", "name": "PP2A(A:C):S112/S121-pSPRY2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040761", "map_id": "none", "name": "FGFR3b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040755", "map_id": "A0A3Q1MPT9", "name": "FGFR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10036461", "map_id": "none", "name": "FGFR3b-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040759", "map_id": "none", "name": "FGFR3b homodimer bound to FGF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040779", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036473", "map_id": "none", "name": "Activated FGFR3b homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083933", "map_id": "none", "name": "GALNT3 transfers GalNAc to FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_735700", "map_id": "CHEBI:16650", "name": "UDP-GalNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10083928", "map_id": "E1BJU2", "name": "FGF23", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10083930", "map_id": "E1BJU2", "name": "FGF23", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10052428", "map_id": "E1BBP1", "name": "GALNT3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000018541", "map_id": "ENSBTAT00000018541", "name": "GALNT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083935", "map_id": "none", "name": "GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10036373", "map_id": "E1BJU2", "name": "FGF23", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10040782", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR3c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040751", "map_id": "none", "name": "FGFR3c homodimer bound to FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036485", "map_id": "none", "name": "Activated FGFR3c homodimer ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040753", "map_id": "none", "name": "FGFR3c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040747", "map_id": "A0A3Q1MPT9", "name": "FGFR3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10036475", "map_id": "none", "name": "FGFR3c-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10073240", "map_id": "none", "name": "FGFR4-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065247", "map_id": "none", "name": "Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073192", "map_id": "none", "name": "Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073188", "map_id": "none", "name": "Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10035515", "map_id": "P32871", "name": "PIK3CA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10073190", "map_id": "none", "name": "Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073237", "map_id": "none", "name": "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073177", "map_id": "none", "name": "Activated FGFR4:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073168", "map_id": "none", "name": "Activated FGFR4:p-FRS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073170", "map_id": "none", "name": "Activated FGFR4:p-FRS:PTPN11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073166", "map_id": "none", "name": "Activated FGFR4 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073161", "map_id": "none", "name": "Activated FGFR4:FRS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073163", "map_id": "none", "name": "Activated FGFR4:p-FRS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073182", "map_id": "none", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073179", "map_id": "none", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073184", "map_id": "none", "name": "Activated FGFR4:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073028", "map_id": "none", "name": "Activated FGFR4 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073023", "map_id": "none", "name": "Activated FGFR4:FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10065243", "map_id": "none", "name": "Activated FGFR4:p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073026", "map_id": "none", "name": "Activated FGFR4:p-8T-FRS2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073031", "map_id": "none", "name": "Activated FGFR4 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073175", "map_id": "none", "name": "Activated FGFR4 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073172", "map_id": "none", "name": "Activated FGFR4:p-FRS:p-PTPN11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087367", "map_id": "none", "name": "Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10072939", "map_id": "none", "name": "p-4Y-PLCG1 dissociates from activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072924", "map_id": "none", "name": "activated FGFR4:p-4Y-PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072927", "map_id": "none", "name": "Activated FGFR4 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072922", "map_id": "none", "name": "activated FGFR4:PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072933", "map_id": "none", "name": "Activated FGFR4 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10073246", "map_id": "none", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073186", "map_id": "none", "name": "Activated FGFR4:p-FRS2:p-PTPN11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073217", "map_id": "none", "name": "Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073222", "map_id": "none", "name": "CBL ubiquitinates FRS2 and FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073219", "map_id": "none", "name": "Ub-Activated FGFR4 complex:Ub-p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040776", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040767", "map_id": "none", "name": "FGFR4 homodimer bound to FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036502", "map_id": "none", "name": "Activated FGFR4 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040769", "map_id": "none", "name": "FGFR4 binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10036500", "map_id": "none", "name": "FGFR4-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040763", "map_id": "F1MN51", "name": "FGFR4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10057704", "map_id": "none", "name": "FGFR4 binds HS:KLB:FGF19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036498", "map_id": "E1BFP8", "name": "FGF19", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10036506", "map_id": "F1N4S9", "name": "KLB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10057702", "map_id": "none", "name": "FGFR4:HS:KLB:FGF19", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057707", "map_id": "none", "name": "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036508", "map_id": "none", "name": "Activated FGFR4 bound to FGF19:BetaKlotho", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040720", "map_id": "none", "name": "FGFR2c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036438", "map_id": "none", "name": "FGFR2c-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040706", "map_id": "A0A3Q1LRU7", "name": "FGFR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10040718", "map_id": "none", "name": "FGFR2c homodimer bound to FGF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040788", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR2c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036459", "map_id": "none", "name": "Activated FGFR2c homodimer bound to FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040744", "map_id": "none", "name": "FGFR2b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036405", "map_id": "none", "name": "FGFR2b-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040722", "map_id": "A0A3Q1LRU7", "name": "FGFR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10040734", "map_id": "none", "name": "FGFR2b homodimer bound to FGF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040742", "map_id": "none", "name": "FGFBP:FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q9MZ06", "map_id": "Q9MZ06", "name": "FGFBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044642", "map_id": "ENSBTAT00000044642", "name": "FGFBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040785", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR2b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036432", "map_id": "none", "name": "Activated FGFR2b homodimer bound to FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073328", "map_id": "none", "name": "FGFBPs bind FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040740", "map_id": "Q9MZ06", "name": "FGFBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10040736", "map_id": "none", "name": "FGF2,7,10,22", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10072909", "map_id": "none", "name": "Activated FGFR2 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072904", "map_id": "none", "name": "activated FGFR2:PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072906", "map_id": "none", "name": "activated FGFR2:p-4Y-PLCG1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072929", "map_id": "none", "name": "p-4Y-PLCG1 dissociates from activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065255", "map_id": "none", "name": "Activated FGFR2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072931", "map_id": "none", "name": "Activated FGFR2 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10073001", "map_id": "none", "name": "Activated FGFR2:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072988", "map_id": "none", "name": "Activated FGFR2:pY-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072990", "map_id": "none", "name": "Activated FGFR2:pY-SHC1:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073004", "map_id": "none", "name": "Activated FGFR2 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072997", "map_id": "none", "name": "Activated FGFR2:SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072993", "map_id": "none", "name": "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10072999", "map_id": "none", "name": "Activated FGFR2 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073129", "map_id": "none", "name": "Activated FGFR2:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065257", "map_id": "none", "name": "Activated FGFR2:p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073124", "map_id": "none", "name": "Activated FGFR2:p-FRS:PTPN11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087370", "map_id": "none", "name": "Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065259", "map_id": "none", "name": "Activated FGFR2:p-FRS2:p-PTPN11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073133", "map_id": "none", "name": "Activated FGFR2:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073131", "map_id": "none", "name": "Activated FGFR2:p-FRS:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072976", "map_id": "none", "name": "Activated FGFR2 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072961", "map_id": "none", "name": "Activated FGFR2:FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072974", "map_id": "none", "name": "Activated FGFR2:p-8T-FRS2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073136", "map_id": "none", "name": "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10072979", "map_id": "none", "name": "Activated FGFR2 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073127", "map_id": "none", "name": "Activated FGFR2 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10073231", "map_id": "none", "name": "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065263", "map_id": "none", "name": "Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073208", "map_id": "none", "name": "CBL ubiquitinates FRS2 and FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073203", "map_id": "none", "name": "Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073205", "map_id": "none", "name": "Ub-Activated FGFR2 complex:Ub-p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073242", "map_id": "none", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073071", "map_id": "none", "name": "FGFRL1 binds SPRED1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073053", "map_id": "none", "name": "FGFRL1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MQI5", "map_id": "F1MQI5", "name": "FGFRL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039444", "map_id": "ENSBTAT00000039444", "name": "FGFRL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073067", "map_id": "none", "name": "SPRED1/2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MP99", "map_id": "A0A3Q1MP99", "name": "SPRED2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068413", "map_id": "ENSBTAT00000068413", "name": "SPRED2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MH60", "map_id": "F1MH60", "name": "SPRED1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046117", "map_id": "ENSBTAT00000046117", "name": "SPRED1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073069", "map_id": "none", "name": "FGFRL1 dimer:SPRED1/2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073077", "map_id": "none", "name": "FGFRL1 dimer binds FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073073", "map_id": "none", "name": "FGFRL1-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10073075", "map_id": "none", "name": "FGFRL1-binding FGFs:FGFRL1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073199", "map_id": "none", "name": "CBL ubiquitinates FRS2 and FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073194", "map_id": "none", "name": "Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073196", "map_id": "none", "name": "Ub-Activated FGFR1 complex:Ub-p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073201", "map_id": "none", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065249", "map_id": "none", "name": "Activated FGFR1:p-FRS2:p-PTPN11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040794", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040702", "map_id": "none", "name": "FGFR1c homodimer bound to FGF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036379", "map_id": "none", "name": "Activated FGFR1c homodimer ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040704", "map_id": "none", "name": "FGFR1c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10036375", "map_id": "none", "name": "FGFR1c-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040698", "map_id": "A0A3Q1LUE0", "name": "FGFR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10040696", "map_id": "none", "name": "FGFR1b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040690", "map_id": "A0A3Q1LUE0", "name": "FGFR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10036328", "map_id": "none", "name": "FGFR1b-binding FGFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040694", "map_id": "none", "name": "FGFR1b homodimer bound to FGF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040791", "map_id": "none", "name": "Autocatalytic phosphorylation of FGFR1b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036344", "map_id": "none", "name": "Activated FGFR1b homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040860", "map_id": "none", "name": "Autocatalytic phosphorylation of Klotho-bound FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040771", "map_id": "none", "name": "FGF23 bound to Klotho and FGFR1c", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036399", "map_id": "none", "name": "Activated FGFR1c bound to FGF23:Klotho", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040773", "map_id": "none", "name": "FGFR1c binds to Klotho-bound FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10036397", "map_id": "none", "name": "Klotho bound to FGF23", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073097", "map_id": "none", "name": "Activated FGFR1 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073094", "map_id": "none", "name": "Activated FGFR1:FRS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072950", "map_id": "none", "name": "Activated FGFR1:p-FRS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073113", "map_id": "none", "name": "Activated FGFR1:p-FRS phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073104", "map_id": "none", "name": "Activated FGFR1:p-FRS:PTPN11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073110", "map_id": "none", "name": "Activated FGFR1:p-FRS:p-PTPN11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073083", "map_id": "none", "name": "Activated FGFR1 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065233", "map_id": "none", "name": "Activated FGFR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073079", "map_id": "none", "name": "Activated FGFR1:FRS2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072957", "map_id": "none", "name": "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072954", "map_id": "none", "name": "Activated FGFR1:p-FRS2:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087373", "map_id": "none", "name": "Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073090", "map_id": "none", "name": "Activated FGFR1 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065235", "map_id": "none", "name": "Activated FGFR1:p-FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073106", "map_id": "none", "name": "Activated FGFR1:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072952", "map_id": "none", "name": "Activated FGFR1:p-FRS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073108", "map_id": "none", "name": "Activated FGFR1:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073225", "map_id": "none", "name": "FGFR1-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065239", "map_id": "none", "name": "Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073115", "map_id": "none", "name": "Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065251", "map_id": "none", "name": "Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10065253", "map_id": "none", "name": "Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073228", "map_id": "none", "name": "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073087", "map_id": "none", "name": "Activated FGFR1 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073085", "map_id": "none", "name": "Activated FGFR1:SHC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073119", "map_id": "none", "name": "Activated FGFR1:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073099", "map_id": "none", "name": "Activated FGFR1:p-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073117", "map_id": "none", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073102", "map_id": "none", "name": "Activated FGFR1 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073122", "map_id": "none", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10073326", "map_id": "none", "name": "Activated FGFR1 binds FLRT1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073322", "map_id": "none", "name": "FLRT1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N0R7", "map_id": "F1N0R7", "name": "FLRT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004298", "map_id": "ENSBTAT00000004298", "name": "FLRT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MY74", "map_id": "G3MY74", "name": "FLRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065908", "map_id": "ENSBTAT00000065908", "name": "FLRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVT1", "map_id": "F1MVT1", "name": "FLRT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028517", "map_id": "ENSBTAT00000028517", "name": "FLRT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073324", "map_id": "none", "name": "Activated FGFR1:FLRT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072937", "map_id": "none", "name": "Activated FGFR1 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072915", "map_id": "none", "name": "activated FGFR1:PLCG1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072920", "map_id": "none", "name": "Activated FGFR1 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072917", "map_id": "none", "name": "activated FGFR1:p-4Y-PLCG1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072935", "map_id": "none", "name": "p-4Y-PLCG1 dissociates from activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10091689", "map_id": "none", "name": "PDGFRs bind type II TKI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9674079", "map_id": "none", "name": "type II PDGFR-binding tyrosine kinase inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040472", "map_id": "none", "name": "PDGFRA, PDGFRB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1ME99", "map_id": "A0A3Q1ME99", "name": "PDGFRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067659", "map_id": "ENSBTAT00000067659", "name": "PDGFRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N3Z8", "map_id": "A0A3Q1N3Z8", "name": "PDGFRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086976", "map_id": "ENSBTAT00000086976", "name": "PDGFRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091687", "map_id": "none", "name": "PDGFR:type II PDGFR-binding TKIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046666", "map_id": "none", "name": "Release of novel PDGFs as latent factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046658", "map_id": "none", "name": "PDGF-C chain precursor dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BJY4", "map_id": "E1BJY4", "name": "PDGFC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061070", "map_id": "ENSBTAT00000061070", "name": "PDGFC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046664", "map_id": "none", "name": "PDGF-C chain precursor dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10046677", "map_id": "none", "name": "Extracellular processing of novel PDGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046672", "map_id": "E1BJY4", "name": "PDGFC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046670", "map_id": "none", "name": "PDGF-C chain dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10046674", "map_id": "none", "name": "serine-type endopeptidases involved in novel PDGF processing", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A452DIF6", "map_id": "A0A452DIF6", "name": "PLAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001642", "map_id": "ENSBTAT00000001642", "name": "PLAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046660", "map_id": "none", "name": "Translocation of PDGF from ER to Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10046654", "map_id": "none", "name": "PDGF-C chain precursor dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10057850", "map_id": "none", "name": "Phosphorylation of GAB2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043813", "map_id": "none", "name": "GAB2:GRB2:p-SHP2:p-KIT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057847", "map_id": "none", "name": "p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057854", "map_id": "none", "name": "Recruitment of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057840", "map_id": "none", "name": "p-JAK2:SFKs:p-KIT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057852", "map_id": "none", "name": "p-JAK2:SFKs:p-KIT complex:STATs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057872", "map_id": "none", "name": "Synthesis of PIP3 from PIP2 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057869", "map_id": "none", "name": "PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058480", "map_id": "none", "name": "Disassociation and translocation of STATs to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10058476", "map_id": "none", "name": "p-JAK2:SFKs:p-KIT complex:p-STAT dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091667", "map_id": "none", "name": "KIT binds type II TKIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043782", "map_id": "A0A452DHX3", "name": "KIT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_9669722", "map_id": "none", "name": "type II KIT binding TKIs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091665", "map_id": "none", "name": "KIT:type II TKIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057845", "map_id": "none", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043807", "map_id": "none", "name": "p-SHP2:p-KIT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043809", "map_id": "none", "name": "GRB2:p-SHP2:p-KIT complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043832", "map_id": "none", "name": "Recruitment of CBL to KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043828", "map_id": "none", "name": "Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MRH8", "map_id": "F1MRH8", "name": "SH2B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012781", "map_id": "ENSBTAT00000012781", "name": "SH2B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043830", "map_id": "none", "name": "CBL:Grb2/p-APS:p-c-Kit complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057867", "map_id": "none", "name": "Phosphorylation of APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057864", "map_id": "none", "name": "APS dimer:p-c-Kit:SFKs complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043826", "map_id": "none", "name": "p-APS dimer:p-KIT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058474", "map_id": "none", "name": "Phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10058471", "map_id": "none", "name": "p-JAK2:SFKs:p-KIT complex:p-STATs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058478", "map_id": "none", "name": "Dimerization of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10057857", "map_id": "none", "name": "Activation of RAS by p-KIT bound SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043817", "map_id": "none", "name": "GRB2:SOS1:p-KIT complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043815", "map_id": "none", "name": "Indirect recruitment of GAB2 to p-KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043811", "map_id": "A0A3Q1M864", "name": "GAB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091751", "map_id": "none", "name": "KIT binds ripretinib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9674322", "map_id": "none", "name": "ripretinib", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091749", "map_id": "none", "name": "KIT:ripretinib", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057862", "map_id": "none", "name": "Phosphorylation of SHP2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057859", "map_id": "none", "name": "SHP2:SFKs:p-KIT:sSCF dimer:p-KIT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10041657", "map_id": "none", "name": "NRP-1 forms a ternary complex with VEGF165 and VEGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10041653", "map_id": "E1BMX5", "name": "NRP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000026471", "map_id": "ENSBTAT00000026471", "name": "NRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041655", "map_id": "none", "name": "NRP1:VEGFR2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BMX5", "map_id": "E1BMX5", "name": "NRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041649", "map_id": "none", "name": "Homodimerization of VEGF proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10041441", "map_id": "Q9XS50", "name": "VEGFC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10070651", "map_id": "none", "name": "Src kinases phosphorylate VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070647", "map_id": "none", "name": "PIP3:VAV1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10070649", "map_id": "none", "name": "p-VAV family:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10070580", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BLY9", "map_id": "E1BLY9", "name": "phospho-SHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034285", "map_id": "ENSBTAT00000034285", "name": "phospho-SHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070589", "map_id": "none", "name": "SRC-1 phosphorylates p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070586", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070657", "map_id": "none", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070655", "map_id": "none", "name": "PKCA,PKCB,PKCD,PKCZ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070628", "map_id": "none", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070612", "map_id": "none", "name": "p-PKC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10070626", "map_id": "none", "name": "DAG:active PKC:Ca+2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070615", "map_id": "none", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10069535", "map_id": "none", "name": "Phosphorylation of SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069530", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7Z041", "map_id": "A7Z041", "name": "SH2D2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046702", "map_id": "ENSBTAT00000046702", "name": "SH2D2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069532", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071504", "map_id": "none", "name": "AXL autophosphorylates on Y772 and Y814", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071501", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MRN2", "map_id": "A0A3Q1MRN2", "name": "AXL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075025", "map_id": "ENSBTAT00000075025", "name": "AXL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070638", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071506", "map_id": "none", "name": "AXL binds SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071499", "map_id": "A0A3Q1MRN2", "name": "AXL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10070645", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070642", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071508", "map_id": "none", "name": "p-AXL binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070640", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070676", "map_id": "none", "name": "PAK2 binds NCK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047604", "map_id": "none", "name": "PAK2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10070672", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q1LZB2", "map_id": "Q1LZB2", "name": "NCK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024518", "map_id": "ENSBTAT00000024518", "name": "NCK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070674", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070624", "map_id": "none", "name": "FYN autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070619", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10070621", "map_id": "none", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070594", "map_id": "none", "name": "PTK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070591", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:p-SHB:PTK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10070578", "map_id": "none", "name": "VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070596", "map_id": "none", "name": "SRC-1 binds p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10056781", "map_id": "none", "name": "ERBB4 binds NRGs or EGF-like ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056771", "map_id": "none", "name": "EGF-like ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10056765", "map_id": "A0A3Q1MKB4", "name": "ERBB4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10056779", "map_id": "none", "name": "NRGs/EGF-like ligands:ERBB4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057151", "map_id": "none", "name": "Homodimerization of ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10057149", "map_id": "none", "name": "ERBB4 homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057166", "map_id": "none", "name": "Trans-autophosphorylation of ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10057184", "map_id": "none", "name": "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057181", "map_id": "none", "name": "PI3K:p-ERBB4cyt1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090971", "map_id": "none", "name": "ERBB4s80 binds to SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057248", "map_id": "E1BIM8", "name": "phospho-SRC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10057211", "map_id": "none", "name": "ERBB4s80", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10057250", "map_id": "none", "name": "ERBB4s80:MyrG-p-Y419-SRC", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057262", "map_id": "none", "name": "ERBB4 ubiquitination by WWP1/ITCH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057257", "map_id": "none", "name": "ERBB4/m80/s80:WWP1/ITCH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q32PG0", "map_id": "Q32PG0", "name": "WWP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020867", "map_id": "ENSBTAT00000020867", "name": "WWP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057259", "map_id": "none", "name": "Ub-ERBB4:WWP1/ITCH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057264", "map_id": "none", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10055126", "map_id": "Q32PG0", "name": "WWP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057255", "map_id": "none", "name": "ERBB4/ERBB4m80/ERBB4s80", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10057272", "map_id": "none", "name": "WWOX binds ERBB4s80", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057268", "map_id": "A0A3Q1LVN4", "name": "WWOX", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000086215", "map_id": "ENSBTAT00000086215", "name": "WWOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057270", "map_id": "none", "name": "ERBB4s80:WWOX", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LVN4", "map_id": "A0A3Q1LVN4", "name": "WWOX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057298", "map_id": "none", "name": "Translocation of cytosolic ERBB4s80 to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057296", "map_id": "none", "name": "ERBB4s80", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10057236", "map_id": "none", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057201", "map_id": "none", "name": "ERBB4m80", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10057233", "map_id": "none", "name": "gamma-secretase complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LNM1", "map_id": "A0A3Q1LNM1", "name": "APH1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068424", "map_id": "ENSBTAT00000068424", "name": "APH1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBH7", "map_id": "A0A3Q1MBH7", "name": "APH1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086383", "map_id": "ENSBTAT00000086383", "name": "APH1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDC6", "map_id": "A0A3Q1MDC6", "name": "NCSTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075241", "map_id": "ENSBTAT00000075241", "name": "NCSTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5G235", "map_id": "Q5G235", "name": "PSENEN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024745", "map_id": "ENSBTAT00000024745", "name": "PSENEN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057252", "map_id": "none", "name": "Translocation of ERBB4s80 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057246", "map_id": "none", "name": "ERBB4s80", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057284", "map_id": "none", "name": "Translocation of ERBB4s80:YAP1 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057278", "map_id": "none", "name": "ERBB4s80:YAP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10057282", "map_id": "none", "name": "ERBB4s80:YAP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057286", "map_id": "none", "name": "ERBB4s80 binds YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10084080", "map_id": "none", "name": "MST1R autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10084065", "map_id": "none", "name": "MST1 dimer:2xMST1R dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BCZ6", "map_id": "E1BCZ6", "name": "phospho-MST1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020028", "map_id": "ENSBTAT00000020028", "name": "phospho-MST1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDW7", "map_id": "E1BDW7", "name": "MST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030663", "map_id": "ENSBTAT00000030663", "name": "MST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084077", "map_id": "none", "name": "MST1 dimer:2x p-4Y-MST1R dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084067", "map_id": "none", "name": "MST1 dimer:MST1R dimer binds MST1R dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10080868", "map_id": "none", "name": "MST1 dimer:MST1R dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10080866", "map_id": "none", "name": "MST1R dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10080870", "map_id": "none", "name": "MST1 binds MST1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10080858", "map_id": "none", "name": "MST1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10091705", "map_id": "none", "name": "AAMP binds EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_459", "compartment_display": "cytoplasm" }, { "id": "species_10091695", "map_id": "Q3SZK1", "name": "AAMP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000005126", "map_id": "ENSBTAT00000005126", "name": "AAMP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091703", "map_id": "none", "name": "EGFR:AAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3SZK1", "map_id": "Q3SZK1", "name": "AAMP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040393", "map_id": "none", "name": "Ubiquitination of stimulated EGFR (CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040366", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:p-Y371-CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040388", "map_id": "none", "name": "EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040458", "map_id": "none", "name": "Phosphorylation of CBL (EGFR:GRB2:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040455", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:CBL:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040395", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040460", "map_id": "none", "name": "Localization of CBL:GRB2 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040449", "map_id": "none", "name": "CBL:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040447", "map_id": "none", "name": "CBL ubiquitinates Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040440", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QLQ1", "map_id": "A6QLQ1", "name": "SPRY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028307", "map_id": "ENSBTAT00000028307", "name": "SPRY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040444", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040462", "map_id": "none", "name": "CBL binds and ubiquitinates phosphorylated Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040382", "map_id": "none", "name": "SPRY1/2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040369", "map_id": "none", "name": "Phosphorylation of CBL (EGFR:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040361", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040432", "map_id": "none", "name": "Ubiquitination of stimulated EGFR (CBL:GRB2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040425", "map_id": "none", "name": "EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040430", "map_id": "F1MME1", "name": "PTPRK", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000061187", "map_id": "ENSBTAT00000061187", "name": "PTPRK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040451", "map_id": "none", "name": "CBL binds to GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040386", "map_id": "none", "name": "Sprouty lures CBL away from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040374", "map_id": "Q08E39", "name": "phospho-SPRY2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040384", "map_id": "none", "name": "CBL:SPRY1/2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040453", "map_id": "none", "name": "Binding of CBL to EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10040421", "map_id": "none", "name": "Assembly of EGFR complex in clathrin-coated vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040417", "map_id": "none", "name": "CIN85:endophilin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DX1", "map_id": "Q08DX1", "name": "SH3GL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018755", "map_id": "ENSBTAT00000018755", "name": "SH3GL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M839", "map_id": "A0A3Q1M839", "name": "SH3KBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073657", "map_id": "ENSBTAT00000073657", "name": "SH3KBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040419", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040331", "map_id": "none", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040301", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040303", "map_id": "none", "name": "GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040283", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040286", "map_id": "none", "name": "SHC1 phosphorylation by phosphorylated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040256", "map_id": "none", "name": "EGF-like ligands:p-6Y EGFR:SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040258", "map_id": "none", "name": "SHC1 binds to the phosphorylated EGF receptor:ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040289", "map_id": "none", "name": "EGFR autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040227", "map_id": "none", "name": "EGF-like ligands:EGFR dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10036616", "map_id": "none", "name": "GRB2-1 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035489", "map_id": "F1N7C3", "name": "SOS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040317", "map_id": "none", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040314", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:GRB2:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040326", "map_id": "none", "name": "GRB2:SOS1 complex binds to EGF:EGFR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040323", "map_id": "none", "name": "EGFR binds EGF ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10040223", "map_id": "none", "name": "EGF-like ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040225", "map_id": "none", "name": "EGFR:EGF-like ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040321", "map_id": "F1MZV0", "name": "LRIG1", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000030750", "map_id": "ENSBTAT00000030750", "name": "LRIG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040229", "map_id": "none", "name": "EGFR dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10044472", "map_id": "none", "name": "Active PLC-gamma1 dissociates from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044467", "map_id": "none", "name": "EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044465", "map_id": "none", "name": "Phospholipase C-gamma1 binds to the activated EGF receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043197", "map_id": "F1MYF9", "name": "PLCG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044463", "map_id": "none", "name": "EGF-like ligands:p-6Y-EGFR:PLCG1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044470", "map_id": "none", "name": "EGFR activates PLC-gamma1 by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040310", "map_id": "none", "name": "Phosphorylation of EGFR by SRC kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10035536", "map_id": "none", "name": "GRB2-1:SOS1 binds p-Y427-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035532", "map_id": "Q0IIE2", "name": "phospho-SHC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035534", "map_id": "none", "name": "GRB2-1:SOS1:p-Y427-SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075065", "map_id": "none", "name": "GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036626", "map_id": "none", "name": "GRB2-1:p-4S-SOS1:p-Y427-SHC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036624", "map_id": "none", "name": "GRB2-1:p-4S-SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075097", "map_id": "none", "name": "GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036628", "map_id": "none", "name": "GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083487", "map_id": "none", "name": "SOCS3 binds activated PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083485", "map_id": "none", "name": "p-Y342-PTK6:SOCS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083565", "map_id": "none", "name": "PTK6 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083556", "map_id": "none", "name": "p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1))", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q32KY4", "map_id": "Q32KY4", "name": "CDK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079975", "map_id": "ENSBTAT00000079975", "name": "CDK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIV3", "map_id": "A0A452DIV3", "name": "CCND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023277", "map_id": "ENSBTAT00000023277", "name": "CCND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLS3", "map_id": "A6QLS3", "name": "phospho-CDKN1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083562", "map_id": "none", "name": "p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1))", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083558", "map_id": "none", "name": "Activated PTK6 binds CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083554", "map_id": "none", "name": "CDKN1B:(CDK4:CCND1,(CDK2:CCNE1))", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083646", "map_id": "none", "name": "PTK6 binds ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083642", "map_id": "A0A3Q1M4A0", "name": "ARAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000079568", "map_id": "ENSBTAT00000079568", "name": "ARAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083644", "map_id": "none", "name": "p-Y342-PTK6:ARAP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4A0", "map_id": "A0A3Q1M4A0", "name": "ARAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083632", "map_id": "none", "name": "PTK6 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10083652", "map_id": "none", "name": "PTK6 phosphorylates ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083649", "map_id": "A0A3Q1M4A0", "name": "phospho-ARAP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083638", "map_id": "none", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083635", "map_id": "A0A3Q1LN00", "name": "phospho-CBL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083690", "map_id": "none", "name": "PTK6 phosphorylates ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083682", "map_id": "none", "name": "p-Y342-PTK6:ARHGAP35", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10083687", "map_id": "E1B801", "name": "phospho-ARHGAP35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083581", "map_id": "none", "name": "PTK6 binds PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070667", "map_id": "F1MFD1", "name": "PXN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024101", "map_id": "ENSBTAT00000024101", "name": "PXN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083579", "map_id": "none", "name": "p-Y342-PTK6:PXN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MFD1", "map_id": "F1MFD1", "name": "PXN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083629", "map_id": "none", "name": "PTK6 phosphorylates BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083620", "map_id": "none", "name": "p-Y342-PTK6:BCAR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MQ07", "map_id": "A0A3Q1MQ07", "name": "phospho-BCAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073322", "map_id": "ENSBTAT00000073322", "name": "phospho-BCAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083626", "map_id": "A0A3Q1MQ07", "name": "phospho-BCAR1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083695", "map_id": "none", "name": "ARHGAP35 stimulates RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083692", "map_id": "none", "name": "p-Y1105-ARHGAP35:RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083697", "map_id": "none", "name": "ARHGAP35 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10083588", "map_id": "none", "name": "PTK6 phosphorylates PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083585", "map_id": "F1MFD1", "name": "phospho-PXN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083684", "map_id": "none", "name": "PTK6 binds ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083680", "map_id": "E1B801", "name": "ARHGAP35", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083622", "map_id": "none", "name": "PTK6 binds BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083618", "map_id": "A0A3Q1MQ07", "name": "BCAR1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083707", "map_id": "none", "name": "SRMS phosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083700", "map_id": "E1BNA8", "name": "phospho-PTK6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083704", "map_id": "F1N1Q0", "name": "SRMS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000002574", "map_id": "ENSBTAT00000002574", "name": "SRMS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083726", "map_id": "none", "name": "PTPN1 binds PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055952", "map_id": "A6QQN2", "name": "PTPN1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008678", "map_id": "ENSBTAT00000008678", "name": "PTPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083724", "map_id": "none", "name": "p-Y342-PTK6:PTPN1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QQN2", "map_id": "A6QQN2", "name": "PTPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083729", "map_id": "none", "name": "PTPN1 dephosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090428", "map_id": "none", "name": "EPOR-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090425", "map_id": "none", "name": "PI3K bound to EPOR", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MEQ7", "map_id": "F1MEQ7", "name": "phospho-EPOR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010781", "map_id": "ENSBTAT00000010781", "name": "phospho-EPOR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089841", "map_id": "none", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047493", "map_id": "none", "name": "PI3K gamma", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10089837", "map_id": "none", "name": "EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089839", "map_id": "none", "name": "EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090501", "map_id": "none", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10090415", "map_id": "none", "name": "EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073851", "map_id": "none", "name": "mTORC1 phosphorylates AKT1S1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039143", "map_id": "none", "name": "mTORC1:p-T246-AKT1S1:YWHAB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "F1N197", "map_id": "F1N197", "name": "phospho-AKT1S1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007575", "map_id": "ENSBTAT00000007575", "name": "phospho-AKT1S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073848", "map_id": "none", "name": "mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10046572", "map_id": "none", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10042890", "map_id": "none", "name": "p-AMPK heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10046588", "map_id": "none", "name": "RHEB in mTORC1:RHEB:GTP hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10046583", "map_id": "none", "name": "AMPK is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10042880", "map_id": "none", "name": "AMPK heterotrimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10046580", "map_id": "O62829", "name": "PPM1A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024128", "map_id": "ENSBTAT00000024128", "name": "PPM1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049894", "map_id": "none", "name": "AMPK phosphorylates Raptor in the mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10039178", "map_id": "none", "name": "mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10088493", "map_id": "none", "name": "SLC38A9 binds Ragulator:Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039075", "map_id": "A0A3Q1LYC8", "name": "SLC38A9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "species_10039119", "map_id": "none", "name": "Ragulator:RagA,B:GTP:RagC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10039121", "map_id": "none", "name": "Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10073853", "map_id": "none", "name": "AKT1S1 (PRAS40) binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039145", "map_id": "F1N197", "name": "AKT1S1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039147", "map_id": "none", "name": "mTORC1:RHEB:GTP:AKT1S1", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10088496", "map_id": "none", "name": "SLC38A9 transports L-Arg from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428011", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10039059", "map_id": "none", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039055", "map_id": "none", "name": "RHEB:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10039057", "map_id": "none", "name": "RHEB:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10039209", "map_id": "none", "name": "Phosphorylation and inactivation of eEF2K by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039204", "map_id": "E1BEM1", "name": "EEF2K", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023487", "map_id": "ENSBTAT00000023487", "name": "phospho-EEF2K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039207", "map_id": "E1BEM1", "name": "phospho-EEF2K", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039168", "map_id": "F1MNP4", "name": "phospho-RPS6KB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022415", "map_id": "ENSBTAT00000022415", "name": "RPS6KB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039160", "map_id": "none", "name": "Dissociation of phosphorylated 4EBP1 from eIF4E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039133", "map_id": "none", "name": "eIF4E:4E-BP1-P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0P5A7", "map_id": "Q0P5A7", "name": "EIF4EBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039828", "map_id": "ENSBTAT00000039828", "name": "EIF4EBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NEI6", "map_id": "A0A3Q1NEI6", "name": "EIF4E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068997", "map_id": "ENSBTAT00000068997", "name": "EIF4E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034357", "map_id": "A0A3Q1NEI6", "name": "EIF4E", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039131", "map_id": "Q0P5A7", "name": "phospho-EIF4EBP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091741", "map_id": "none", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678687", "map_id": "none", "name": "sirolimus", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039151", "map_id": "P18203", "name": "FKBP1A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010928", "map_id": "ENSBTAT00000010928", "name": "FKBP1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039153", "map_id": "none", "name": "FKBP1A:sirolimus", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P18203", "map_id": "P18203", "name": "FKBP1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039180", "map_id": "none", "name": "mTORC1 phosphorylation of RPS6KB1 (S6K)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039164", "map_id": "F1MNP4", "name": "RPS6KB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039200", "map_id": "none", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034529", "map_id": "none", "name": "Homologues of RPS6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N412", "map_id": "A0A3Q1N412", "name": "RPS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019214", "map_id": "ENSBTAT00000019214", "name": "RPS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8K9", "map_id": "E1B8K9", "name": "RPS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039197", "map_id": "none", "name": "Homologues of p-5S-RPS6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10039155", "map_id": "none", "name": "Phosphorylation of 4E-BP1 by activated mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10034363", "map_id": "none", "name": "eIF4E:4E-BP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072900", "map_id": "none", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039101", "map_id": "none", "name": "RRAGA:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039115", "map_id": "none", "name": "RRAGC,RRAGD:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039117", "map_id": "none", "name": "RagA,B:GTP:RagC,D:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073844", "map_id": "none", "name": "Phosphorylated AKT1S1:mTORC1 binds YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10039141", "map_id": "none", "name": "mTORC1:RHEB:GTP:p-T246-AKT1S1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10037666", "map_id": "A0A140T894", "name": "YWHAB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039127", "map_id": "none", "name": "Formation of active mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039123", "map_id": "none", "name": "mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10072902", "map_id": "none", "name": "Ragulator binds Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039095", "map_id": "none", "name": "Ragulator", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10046602", "map_id": "none", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10046594", "map_id": "none", "name": "IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MM00", "map_id": "F1MM00", "name": "phospho-ERN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022347", "map_id": "ENSBTAT00000022347", "name": "phospho-ERN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046599", "map_id": "none", "name": "p-S724-IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10046604", "map_id": "none", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10046592", "map_id": "F1MM00", "name": "ERN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10085865", "map_id": "none", "name": "CREBRF binds CREB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10085861", "map_id": "E1BPS0", "name": "CREBRF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000065187", "map_id": "ENSBTAT00000065187", "name": "CREBRF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085857", "map_id": "Q8SQ19", "name": "CREB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000015193", "map_id": "ENSBTAT00000015193", "name": "CREB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085863", "map_id": "none", "name": "CREB3:CREBRF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q8SQ19", "map_id": "Q8SQ19", "name": "CREB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPS0", "map_id": "E1BPS0", "name": "CREBRF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060285", "map_id": "none", "name": "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2105007", "map_id": "CHEBI:63846", "name": "Gal(S)-GlcNAc(S)-Gal-GlcNAc(S)-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2104997", "map_id": "CHEBI:63850", "name": "Gal-GlcNAc(S)-Gal-GlcNAc(S)-Gal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1606845", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060282", "map_id": "none", "name": "GALNS oligomer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "F1MU84", "map_id": "F1MU84", "name": "GALNS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006001", "map_id": "ENSBTAT00000006001", "name": "GALNS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091293", "map_id": "none", "name": "HEXB cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2105012", "map_id": "CHEBI:63852", "name": "GlcNAc-Gal-GlcNAc(S)-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2105010", "map_id": "CHEBI:63853", "name": "Gal-GlcNAc(S)-Gal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605658", "map_id": "CHEBI:28037", "name": "GalNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10059946", "map_id": "none", "name": "bHEXB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "H7BWW2", "map_id": "H7BWW2", "name": "HEXB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048411", "map_id": "ENSBTAT00000048411", "name": "HEXB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060293", "map_id": "none", "name": "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2104995", "map_id": "CHEBI:63851", "name": "GlcNAc(S)-Gal-GlcNAc(S)-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060290", "map_id": "F1MXZ0", "name": "GNS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000023218", "map_id": "ENSBTAT00000023218", "name": "GNS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060295", "map_id": "none", "name": "HEXA cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10059941", "map_id": "none", "name": "HEXA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "Q0V8R6", "map_id": "Q0V8R6", "name": "HEXA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017261", "map_id": "ENSBTAT00000017261", "name": "HEXA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063510", "map_id": "none", "name": "Extracellular KSPG translocates to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10063483", "map_id": "none", "name": "KSPG(2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q05443", "map_id": "Q05443", "name": "LUM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002279", "map_id": "ENSBTAT00000002279", "name": "LUM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P13605", "map_id": "P13605", "name": "FMOD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019854", "map_id": "ENSBTAT00000019854", "name": "FMOD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060854", "map_id": "none", "name": "KSPG(2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10038201", "map_id": "none", "name": "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038157", "map_id": "none", "name": "kallikrein:kininogen:C1q binding protein tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T0B6", "map_id": "Q3T0B6", "name": "C1QBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013734", "map_id": "ENSBTAT00000013734", "name": "C1QBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038196", "map_id": "none", "name": "activated kininogen:C1q binding protein tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10038188", "map_id": "none", "name": "Plasma kallikrein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10091546", "map_id": "none", "name": "SERPING1 is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10091544", "map_id": "E1BMJ0", "name": "SERPING1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10038209", "map_id": "E1BMJ0", "name": "SERPING1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10038205", "map_id": "none", "name": "kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038143", "map_id": "none", "name": "C1q binding protein tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10038203", "map_id": "A0A140T8C8", "name": "KNG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038145", "map_id": "none", "name": "KNG:C1q binding protein tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090718", "map_id": "none", "name": "Factor IIa inhibitors (peptide) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9603327", "map_id": "none", "name": "Factor IIa inhibitors (peptide)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038217", "map_id": "none", "name": "Factor IIa inhibitors (peptide):IIa", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038129", "map_id": "none", "name": "factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037535", "map_id": "none", "name": "GPIb-IX-V", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N1G4", "map_id": "F1N1G4", "name": "GP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019525", "map_id": "ENSBTAT00000019525", "name": "GP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG29", "map_id": "E1BG29", "name": "GP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017571", "map_id": "ENSBTAT00000017571", "name": "GP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B863", "map_id": "E1B863", "name": "GP1BB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055945", "map_id": "ENSBTAT00000055945", "name": "GP1BB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038121", "map_id": "none", "name": "factor XI", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LT55", "map_id": "A0A3Q1LT55", "name": "F11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087456", "map_id": "ENSBTAT00000087456", "name": "F11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038127", "map_id": "none", "name": "factor XI:GPIb-IX-V complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091600", "map_id": "none", "name": "FVIII is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10076686", "map_id": "G5E5W1", "name": "F8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10038115", "map_id": "none", "name": "factor VIII", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10091671", "map_id": "none", "name": "Factor VIIIa dissociates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10071934", "map_id": "none", "name": "factor VIIIa", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10091669", "map_id": "none", "name": "factor VIIIa A1:A3-C1-C2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10071930", "map_id": "G5E5W1", "name": "F8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10038166", "map_id": "none", "name": "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10038147", "map_id": "none", "name": "prekallikrein:kininogen:C1q binding protein tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10038163", "map_id": "none", "name": "prolylcarboxypeptidase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MAU4", "map_id": "F1MAU4", "name": "PRCP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047906", "map_id": "ENSBTAT00000047906", "name": "PRCP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090185", "map_id": "none", "name": "Factor IIa inhibitors (compounds) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9603311", "map_id": "none", "name": "Factor IIa inhibitors (compounds)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038215", "map_id": "none", "name": "Factor IIa inhibitors (compounds):IIa", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10071946", "map_id": "none", "name": "factor VIIIa associates with cell membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038174", "map_id": "none", "name": "factor VIIIa", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10038221", "map_id": "none", "name": "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038182", "map_id": "none", "name": "factor XIa:GPIb:GPIX:GPV complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037829", "map_id": "none", "name": "thrombin:cleaved SERPINC1", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10037843", "map_id": "none", "name": "SERPINE2:GAG:activated thrombin (factor IIa)", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "CHEBI:18085", "map_id": "CHEBI:18085", "name": "CHEBI:18085", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8HZY1", "map_id": "Q8HZY1", "name": "SERPINE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011485", "map_id": "ENSBTAT00000011485", "name": "SERPINE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038219", "map_id": "none", "name": "Factor IIa inhibitors:IIa", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038149", "map_id": "none", "name": "prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10038133", "map_id": "Q2KJ63", "name": "KLKB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10038213", "map_id": "none", "name": "kallikrein binds SERPING1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038211", "map_id": "none", "name": "kallikrein:C1Inh", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10035301", "map_id": "none", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035297", "map_id": "E1B883", "name": "RRN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000006308", "map_id": "ENSBTAT00000006308", "name": "RRN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035293", "map_id": "none", "name": "RNA Polymerase I Holoenzyme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q1RMP0", "map_id": "Q1RMP0", "name": "POLR1H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045075", "map_id": "ENSBTAT00000045075", "name": "POLR1H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32P78", "map_id": "Q32P78", "name": "POLR2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043971", "map_id": "ENSBTAT00000043971", "name": "POLR2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ29", "map_id": "Q3SZ29", "name": "POLR1E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016250", "map_id": "ENSBTAT00000016250", "name": "POLR1E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWA1", "map_id": "A7YWA1", "name": "POLR1F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047621", "map_id": "ENSBTAT00000047621", "name": "POLR1F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIX2", "map_id": "E1BIX2", "name": "POLR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008496", "map_id": "ENSBTAT00000008496", "name": "POLR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBC0", "map_id": "Q3ZBC0", "name": "POLR2K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030510", "map_id": "ENSBTAT00000030510", "name": "POLR2K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QVL1", "map_id": "F6QVL1", "name": "POLR1G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032261", "map_id": "ENSBTAT00000032261", "name": "POLR1G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLS0", "map_id": "A6QLS0", "name": "POLR1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018830", "map_id": "ENSBTAT00000018830", "name": "POLR1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32L22", "map_id": "Q32L22", "name": "POLR1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025246", "map_id": "ENSBTAT00000025246", "name": "POLR1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F2Z4H3", "map_id": "F2Z4H3", "name": "POLR2H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000606", "map_id": "ENSBTAT00000000606", "name": "POLR2H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035299", "map_id": "none", "name": "Active RNA Polymerase I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B883", "map_id": "E1B883", "name": "RRN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035254", "map_id": "none", "name": "UBF-1 Binds rDNA Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_350", "compartment_display": "nucleolus" }, { "id": "species_73682", "map_id": "none", "name": "rDNA Promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035051", "map_id": "F1MCZ7", "name": "UBTF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000034806", "map_id": "ENSBTAT00000034806", "name": "UBTF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035053", "map_id": "none", "name": "UBF-1:rDNA Promoter", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MCZ7", "map_id": "F1MCZ7", "name": "UBTF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035231", "map_id": "none", "name": "Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10035252", "map_id": "none", "name": "Chromatin (H3K9me2, 5mC):MBD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G5E683", "map_id": "G5E683", "name": "MBD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053498", "map_id": "ENSBTAT00000053498", "name": "MBD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034224", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034221", "map_id": "none", "name": "PPA1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P37980", "map_id": "P37980", "name": "PPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010311", "map_id": "ENSBTAT00000010311", "name": "PPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050169", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159450", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10050166", "map_id": "none", "name": "PPA2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LXA8", "map_id": "A0A3Q1LXA8", "name": "PPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086411", "map_id": "ENSBTAT00000086411", "name": "PPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_109496", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10038107", "map_id": "none", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038103", "map_id": "Q3SYU2", "name": "EEF2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000005581", "map_id": "ENSBTAT00000005581", "name": "EEF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038105", "map_id": "none", "name": "eEF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SYU2", "map_id": "Q3SYU2", "name": "EEF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038082", "map_id": "none", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034837", "map_id": "none", "name": "60S ribosomal complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DJF6", "map_id": "A0A452DJF6", "name": "RPL17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055065", "map_id": "ENSBTAT00000055065", "name": "RPL17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9XSI3", "map_id": "Q9XSI3", "name": "RPL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020266", "map_id": "ENSBTAT00000020266", "name": "RPL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q861S4", "map_id": "Q861S4", "name": "RPL21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002160", "map_id": "ENSBTAT00000002160", "name": "RPL21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LR67", "map_id": "A0A3Q1LR67", "name": "RPL22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071569", "map_id": "ENSBTAT00000071569", "name": "RPL22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T003", "map_id": "Q3T003", "name": "RPL18A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021033", "map_id": "ENSBTAT00000021033", "name": "RPL18A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BII3", "map_id": "E1BII3", "name": "RPL23A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037203", "map_id": "ENSBTAT00000037203", "name": "RPL23A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61257", "map_id": "P61257", "name": "RPL26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016378", "map_id": "ENSBTAT00000016378", "name": "RPL26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T057", "map_id": "Q3T057", "name": "RPL23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004190", "map_id": "ENSBTAT00000004190", "name": "RPL23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61356", "map_id": "P61356", "name": "RPL27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023183", "map_id": "ENSBTAT00000023183", "name": "RPL27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q862I1", "map_id": "Q862I1", "name": "RPL24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017905", "map_id": "ENSBTAT00000017905", "name": "RPL24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P39872", "map_id": "P39872", "name": "RPL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004188", "map_id": "ENSBTAT00000004188", "name": "RPL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DT1", "map_id": "Q58DT1", "name": "RPL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026826", "map_id": "ENSBTAT00000026826", "name": "RPL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIZ2", "map_id": "A0A452DIZ2", "name": "RPL11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027850", "map_id": "ENSBTAT00000027850", "name": "RPL11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DQ3", "map_id": "Q58DQ3", "name": "RPL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033359", "map_id": "ENSBTAT00000033359", "name": "RPL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9E6", "map_id": "Q5E9E6", "name": "RPL10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025963", "map_id": "ENSBTAT00000025963", "name": "RPL10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0S6", "map_id": "Q3T0S6", "name": "RPL8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037367", "map_id": "ENSBTAT00000037367", "name": "RPL8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4M0", "map_id": "A0A3Q1M4M0", "name": "RPL13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036905", "map_id": "ENSBTAT00000036905", "name": "RPL13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBQ5", "map_id": "Q2TBQ5", "name": "RPL7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015358", "map_id": "ENSBTAT00000015358", "name": "RPL7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61284", "map_id": "P61284", "name": "RPL12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009155", "map_id": "ENSBTAT00000009155", "name": "RPL12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G8JKV5", "map_id": "G8JKV5", "name": "RPL14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084955", "map_id": "ENSBTAT00000084955", "name": "RPL14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SYR7", "map_id": "Q3SYR7", "name": "RPL9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019298", "map_id": "ENSBTAT00000019298", "name": "RPL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LH67", "map_id": "A0A3Q1LH67", "name": "RPL13A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035330", "map_id": "ENSBTAT00000035330", "name": "RPL13A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LST0", "map_id": "A0A3Q1LST0", "name": "RPL15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020729", "map_id": "ENSBTAT00000020729", "name": "RPL15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EAD6", "map_id": "Q5EAD6", "name": "RPL15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T171", "map_id": "Q3T171", "name": "RPL36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075433", "map_id": "ENSBTAT00000075433", "name": "RPL36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHM9", "map_id": "E1BHM9", "name": "RPL35A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015544", "map_id": "ENSBTAT00000015544", "name": "RPL35A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MIC0", "map_id": "Q3MIC0", "name": "RPL37A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071825", "map_id": "ENSBTAT00000071825", "name": "RPL37A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79244", "map_id": "P79244", "name": "RPL37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006781", "map_id": "ENSBTAT00000006781", "name": "RPL37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DW0", "map_id": "Q58DW0", "name": "RPL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006866", "map_id": "ENSBTAT00000006866", "name": "RPL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDN4", "map_id": "F1MDN4", "name": "RPLP0", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055086", "map_id": "ENSBTAT00000055086", "name": "RPLP0", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32PB9", "map_id": "Q32PB9", "name": "RPL38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042547", "map_id": "ENSBTAT00000042547", "name": "RPL38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DW5", "map_id": "Q58DW5", "name": "RPL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002626", "map_id": "ENSBTAT00000002626", "name": "RPL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42899", "map_id": "P42899", "name": "RPLP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002326", "map_id": "ENSBTAT00000002326", "name": "RPLP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56K14", "map_id": "Q56K14", "name": "RPLP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024376", "map_id": "ENSBTAT00000024376", "name": "RPLP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ34", "map_id": "A0A452DJ34", "name": "RPL28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031754", "map_id": "ENSBTAT00000031754", "name": "RPL28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56K03", "map_id": "Q56K03", "name": "RPL27A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066379", "map_id": "ENSBTAT00000066379", "name": "RPL27A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MG09", "map_id": "F1MG09", "name": "RPL36A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050149", "map_id": "ENSBTAT00000050149", "name": "RPL36A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ59", "map_id": "Q3SZ59", "name": "RPL36A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0D5", "map_id": "Q3T0D5", "name": "RPL30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069699", "map_id": "ENSBTAT00000069699", "name": "RPL30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DW3", "map_id": "Q58DW3", "name": "RPL29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024788", "map_id": "ENSBTAT00000024788", "name": "RPL29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZQ6", "map_id": "Q3SZQ6", "name": "RPL32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020323", "map_id": "ENSBTAT00000020323", "name": "RPL32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T051", "map_id": "Q3T051", "name": "RPL39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087168", "map_id": "ENSBTAT00000087168", "name": "RPL39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHM7", "map_id": "Q3MHM7", "name": "RPL35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004161", "map_id": "ENSBTAT00000004161", "name": "RPL35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML72", "map_id": "F1ML72", "name": "RPL34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071912", "map_id": "ENSBTAT00000071912", "name": "RPL34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038080", "map_id": "none", "name": "60s ribosomal complex lacking L13a subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10034641", "map_id": "A0A3Q1LH67", "name": "RPL13A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10034365", "map_id": "none", "name": "Release of eIF4E from the inactive eIF4E:4E-BP complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034361", "map_id": "Q0P5A7", "name": "EIF4EBP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10034855", "map_id": "none", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034839", "map_id": "none", "name": "80S ribosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3T0F4", "map_id": "Q3T0F4", "name": "RPS10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020719", "map_id": "ENSBTAT00000020719", "name": "RPS10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32PD5", "map_id": "Q32PD5", "name": "RPS19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032643", "map_id": "ENSBTAT00000032643", "name": "RPS19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHA5", "map_id": "E1BHA5", "name": "RPS19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0V4", "map_id": "Q3T0V4", "name": "RPS11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018491", "map_id": "ENSBTAT00000018491", "name": "RPS11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q76I82", "map_id": "Q76I82", "name": "RPS15A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069480", "map_id": "ENSBTAT00000069480", "name": "RPS15A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LLI8", "map_id": "A0A3Q1LLI8", "name": "RPS18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072836", "map_id": "ENSBTAT00000072836", "name": "RPS18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JV9", "map_id": "Q56JV9", "name": "RPS3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013079", "map_id": "ENSBTAT00000013079", "name": "RPS3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0X6", "map_id": "Q3T0X6", "name": "RPS16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028093", "map_id": "ENSBTAT00000028093", "name": "RPS16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P62276", "map_id": "P62276", "name": "RPS29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077396", "map_id": "ENSBTAT00000077396", "name": "RPS29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T169", "map_id": "Q3T169", "name": "RPS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003962", "map_id": "ENSBTAT00000003962", "name": "RPS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFH1", "map_id": "A0A3Q1MFH1", "name": "RPS26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084646", "map_id": "ENSBTAT00000084646", "name": "RPS26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRX4", "map_id": "A0A3Q1LRX4", "name": "RPS15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085499", "map_id": "ENSBTAT00000085499", "name": "RPS15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MIM5", "map_id": "A0A3Q1MIM5", "name": "RPS15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JX6", "map_id": "Q56JX6", "name": "RPS28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003201", "map_id": "ENSBTAT00000003201", "name": "RPS28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JU9", "map_id": "Q56JU9", "name": "RPS24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073736", "map_id": "ENSBTAT00000073736", "name": "RPS24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MR01", "map_id": "F1MR01", "name": "RPS14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075650", "map_id": "ENSBTAT00000075650", "name": "RPS14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNR2", "map_id": "A0A3Q1LNR2", "name": "RPS14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JX5", "map_id": "Q56JX5", "name": "RPS25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040046", "map_id": "ENSBTAT00000040046", "name": "RPS25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KHT7", "map_id": "Q2KHT7", "name": "RPS27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018414", "map_id": "ENSBTAT00000018414", "name": "RPS27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q56JX8", "map_id": "Q56JX8", "name": "RPS13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055693", "map_id": "ENSBTAT00000055693", "name": "RPS13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5N2", "map_id": "A0A3Q1M5N2", "name": "RPSA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085238", "map_id": "ENSBTAT00000085238", "name": "RPSA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEQ3", "map_id": "E1BEQ3", "name": "RPS23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063143", "map_id": "ENSBTAT00000063143", "name": "RPS23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T199", "map_id": "Q3T199", "name": "RPS23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32PB8", "map_id": "Q32PB8", "name": "RPS21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027713", "map_id": "ENSBTAT00000027713", "name": "RPS21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M9K1", "map_id": "A0A3Q1M9K1", "name": "RPS7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082341", "map_id": "ENSBTAT00000082341", "name": "RPS7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNI8", "map_id": "A0A3Q1LNI8", "name": "RPS7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7E5", "map_id": "E1B7E5", "name": "RPS12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080007", "map_id": "ENSBTAT00000080007", "name": "RPS12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCB7", "map_id": "E1BCB7", "name": "LOC511302", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025298", "map_id": "ENSBTAT00000025298", "name": "LOC511302", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNV2", "map_id": "A0A3Q1LNV2", "name": "RPS12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSH8", "map_id": "A0A3Q1MSH8", "name": "RPS12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VE06", "map_id": "A2VE06", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063866", "map_id": "ENSBTAT00000063866", "name": "RPS4Y1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N267", "map_id": "G3N267", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGR7", "map_id": "E1BGR7", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJH2", "map_id": "F1MJH2", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79103", "map_id": "P79103", "name": "RPS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025024", "map_id": "ENSBTAT00000025024", "name": "RPS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQD0", "map_id": "A0A3Q1LQD0", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N0K3", "map_id": "G3N0K3", "name": "RPS4Y1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBL4", "map_id": "A0A3Q1MBL4", "name": "RPS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020462", "map_id": "ENSBTAT00000020462", "name": "RPS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBH8", "map_id": "Q3ZBH8", "name": "RPS20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025484", "map_id": "ENSBTAT00000025484", "name": "RPS20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034853", "map_id": "Q32LC3", "name": "EIF1AX", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023455", "map_id": "ENSBTAT00000023455", "name": "EIF1AX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034609", "map_id": "none", "name": "40S ribosomal complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10034905", "map_id": "none", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034901", "map_id": "none", "name": "40S:eIF3:eIF1A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B7R4", "map_id": "E1B7R4", "name": "EIF3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061515", "map_id": "ENSBTAT00000061515", "name": "EIF3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLZ8", "map_id": "E1BLZ8", "name": "EIF3F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049219", "map_id": "ENSBTAT00000049219", "name": "EIF3F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB16", "map_id": "A7MB16", "name": "EIF3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084055", "map_id": "ENSBTAT00000084055", "name": "EIF3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0V3", "map_id": "Q3T0V3", "name": "EIF3K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014888", "map_id": "ENSBTAT00000014888", "name": "EIF3K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E966", "map_id": "Q5E966", "name": "EIF3I", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077067", "map_id": "ENSBTAT00000077067", "name": "EIF3I", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZCK1", "map_id": "Q3ZCK1", "name": "EIF3L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014281", "map_id": "ENSBTAT00000014281", "name": "EIF3L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T122", "map_id": "Q3T122", "name": "EIF3D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037985", "map_id": "ENSBTAT00000037985", "name": "EIF3D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SYW6", "map_id": "Q3SYW6", "name": "EIF3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023384", "map_id": "ENSBTAT00000023384", "name": "EIF3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32LC3", "map_id": "Q32LC3", "name": "EIF1AX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034385", "map_id": "none", "name": "ternary complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2KHU8", "map_id": "Q2KHU8", "name": "EIF2S3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019064", "map_id": "ENSBTAT00000019064", "name": "EIF2S3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68102", "map_id": "P68102", "name": "EIF2S1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071779", "map_id": "ENSBTAT00000071779", "name": "EIF2S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQI5", "map_id": "A0A3Q1LQI5", "name": "EIF2S2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086329", "map_id": "ENSBTAT00000086329", "name": "EIF2S2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034903", "map_id": "none", "name": "43S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10034383", "map_id": "none", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034379", "map_id": "none", "name": "EIF2S1:EIF2S2:EIF2S3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10034381", "map_id": "none", "name": "eIF2:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10034387", "map_id": "none", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_72393", "map_id": "none", "name": "Met-tRNAi", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060894", "map_id": "none", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060890", "map_id": "none", "name": "ribosome:mRNA:polypeptide+signal", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10060888", "map_id": "none", "name": "Signal Recognition Particle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2T9U1", "map_id": "Q2T9U1", "name": "SRP54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025405", "map_id": "ENSBTAT00000025405", "name": "SRP54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB38", "map_id": "E1BB38", "name": "SRP72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014015", "map_id": "ENSBTAT00000014015", "name": "SRP72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQL9", "map_id": "A6QQL9", "name": "SRP14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019085", "map_id": "ENSBTAT00000019085", "name": "SRP14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYQ7", "map_id": "A0A3Q1LYQ7", "name": "SRP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076619", "map_id": "ENSBTAT00000076619", "name": "SRP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBG7", "map_id": "Q3ZBG7", "name": "SRP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017007", "map_id": "ENSBTAT00000017007", "name": "SRP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060892", "map_id": "none", "name": "SRP:polypeptide+signal:ribosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10048380", "map_id": "none", "name": "Proglucagon translocates from the ER Lumen to secretory granules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10048376", "map_id": "P01272", "name": "GCG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048378", "map_id": "P01272", "name": "GCG", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "reaction_10046723", "map_id": "none", "name": "Glucagon-like Peptide 1 is secreted from intestinal L cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10046709", "map_id": "P01272", "name": "GCG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10046626", "map_id": "P01272", "name": "GCG", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046721", "map_id": "none", "name": "Gustducin Complex (alpha, beta, gamma subunits)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B8Q3", "map_id": "E1B8Q3", "name": "GNG13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026313", "map_id": "ENSBTAT00000026313", "name": "GNG13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NGS8", "map_id": "A0A3Q1NGS8", "name": "GNB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082648", "map_id": "ENSBTAT00000082648", "name": "GNB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046717", "map_id": "none", "name": "GPR119:monoacylglycerol", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E5H9", "map_id": "G5E5H9", "name": "GPR119", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019647", "map_id": "ENSBTAT00000019647", "name": "GPR119", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:71466", "map_id": "CHEBI:71466", "name": "CHEBI:71466", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046130", "map_id": "none", "name": "FFAR4:FFAR4 ligands", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_70115", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10045736", "map_id": "none", "name": "Follitropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045700", "map_id": "P04837", "name": "FSHB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000014462", "map_id": "ENSBTAT00000014462", "name": "FSHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041260", "map_id": "P01217", "name": "CGA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045702", "map_id": "none", "name": "Follitropin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P04837", "map_id": "P04837", "name": "FSHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045734", "map_id": "none", "name": "ACTIVIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1B7M7", "map_id": "E1B7M7", "name": "INHBC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025401", "map_id": "ENSBTAT00000025401", "name": "INHBC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFT5", "map_id": "E1BFT5", "name": "INHBE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008663", "map_id": "ENSBTAT00000008663", "name": "INHBE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045722", "map_id": "none", "name": "INHIB", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P07994", "map_id": "P07994", "name": "INHA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013154", "map_id": "ENSBTAT00000013154", "name": "INHA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045694", "map_id": "none", "name": "Thyrotropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10043952", "map_id": "P01223", "name": "TSHB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10043954", "map_id": "none", "name": "Thyrotropin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10045744", "map_id": "none", "name": "CGA and CGB3 bind to form Human chorionic gonadotropin (hCG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10045740", "map_id": "P04651", "name": "LHB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10045742", "map_id": "none", "name": "Gonadotropin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10045696", "map_id": "none", "name": "Luteinizing hormone is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10041265", "map_id": "P04651", "name": "LHB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10091056", "map_id": "none", "name": "CES1trimer hydrolyses ACEI pro-drugs to ACEIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9619052", "map_id": "none", "name": "ACEI pro-drugs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8878776", "map_id": "CHEBI:30879", "name": "Alcohol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9619021", "map_id": "none", "name": "hydrolysed ACEIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10076366", "map_id": "none", "name": "CES1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1MTP2", "map_id": "F1MTP2", "name": "LOC508916", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032461", "map_id": "ENSBTAT00000032461", "name": "LOC508916", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048461", "map_id": "none", "name": "Cleavage of the signal peptide of Preproghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10048434", "map_id": "Q9BDJ6", "name": "GHRL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048438", "map_id": "Q9BDJ6", "name": "GHRL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048458", "map_id": "none", "name": "Signal Peptidase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P67810", "map_id": "P67810", "name": "SEC11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014925", "map_id": "ENSBTAT00000014925", "name": "SEC11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI36", "map_id": "Q2KI36", "name": "SEC11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015866", "map_id": "ENSBTAT00000015866", "name": "SEC11C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MLX7", "map_id": "A0A3Q1MLX7", "name": "SPCS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083476", "map_id": "ENSBTAT00000083476", "name": "SPCS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEI2", "map_id": "E1BEI2", "name": "SPCS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008726", "map_id": "ENSBTAT00000008726", "name": "SPCS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048429", "map_id": "none", "name": "Acyl Ghrelin and C-Ghrelin are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048421", "map_id": "Q9BDJ6", "name": "GHRL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10048413", "map_id": "Q9BDJ6", "name": "GHRL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10048423", "map_id": "Q9BDJ6", "name": "GHRL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10046085", "map_id": "Q9BDJ6", "name": "GHRL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048427", "map_id": "A0A3Q1LZG1", "name": "GH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000082606", "map_id": "ENSBTAT00000082606", "name": "GH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_422024", "map_id": "CHEBI:35366", "name": "FAs", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10048465", "map_id": "none", "name": "Ghrelin O-acyltransferase octanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_422042", "map_id": "CHEBI:28837", "name": "octanoic acid", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048398", "map_id": "Q9BDJ6", "name": "GHRL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048463", "map_id": "Q9BDJ6", "name": "GHRL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048404", "map_id": "E1BAE4", "name": "MBOAT4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000000986", "map_id": "ENSBTAT00000000986", "name": "MBOAT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048407", "map_id": "none", "name": "Ghrelin O-acyltransferase decanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_422019", "map_id": "CHEBI:30813", "name": "DECA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048400", "map_id": "Q9BDJ6", "name": "GHRL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10049385", "map_id": "none", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_216785", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10049382", "map_id": "E1B955", "name": "SLC30A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "ENSBTAT00000001343", "map_id": "ENSBTAT00000001343", "name": "SLC30A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049392", "map_id": "none", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10049389", "map_id": "A0A3Q1N919", "name": "SLC30A8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "ENSBTAT00000086579", "map_id": "ENSBTAT00000086579", "name": "SLC30A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085101", "map_id": "none", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040838", "map_id": "none", "name": "Microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10085076", "map_id": "none", "name": "Polyglutamylated microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10085098", "map_id": "none", "name": "TTLLs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N2U5", "map_id": "G3N2U5", "name": "TTLL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064999", "map_id": "ENSBTAT00000064999", "name": "TTLL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7E2Z5", "map_id": "A7E2Z5", "name": "TTLL11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017043", "map_id": "ENSBTAT00000017043", "name": "TTLL11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKB4", "map_id": "E1BKB4", "name": "TTLL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069658", "map_id": "ENSBTAT00000069658", "name": "TTLL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085250", "map_id": "none", "name": "TTLL3, TTLL8, TTLL10 polyglycylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085237", "map_id": "none", "name": "Polyglycylated microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10085247", "map_id": "none", "name": "TTLL3,TTLL8,TTLL10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N325", "map_id": "F1N325", "name": "TTLL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034047", "map_id": "ENSBTAT00000034047", "name": "TTLL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N3S4", "map_id": "G3N3S4", "name": "TTLL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065735", "map_id": "ENSBTAT00000065735", "name": "TTLL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087993", "map_id": "none", "name": "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087978", "map_id": "none", "name": "NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BJ64", "map_id": "E1BJ64", "name": "NEDD8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028591", "map_id": "ENSBTAT00000028591", "name": "NEDD8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMW1", "map_id": "Q1RMW1", "name": "UBE2F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037020", "map_id": "ENSBTAT00000037020", "name": "UBE2F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTL8", "map_id": "A0A3Q1MTL8", "name": "DCUN1D1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087337", "map_id": "ENSBTAT00000087337", "name": "DCUN1D1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KII4", "map_id": "Q2KII4", "name": "ELOC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078734", "map_id": "ENSBTAT00000078734", "name": "ELOC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MXH0", "map_id": "A0A3Q1MXH0", "name": "CUL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068692", "map_id": "ENSBTAT00000068692", "name": "CUL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ32", "map_id": "Q3SZ32", "name": "TCEB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026036", "map_id": "ENSBTAT00000026036", "name": "TCEB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0P5F4", "map_id": "Q0P5F4", "name": "RNF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002831", "map_id": "ENSBTAT00000002831", "name": "RNF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHZ2", "map_id": "E1BHZ2", "name": "ASB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024202", "map_id": "ENSBTAT00000024202", "name": "ASB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHZ2", "map_id": "Q3MHZ2", "name": "SPSB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022024", "map_id": "ENSBTAT00000022024", "name": "SPSB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJT8", "map_id": "A0A3Q1MJT8", "name": "SPSB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070334", "map_id": "ENSBTAT00000070334", "name": "SPSB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWW0", "map_id": "F1MWW0", "name": "ASB6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011810", "map_id": "ENSBTAT00000011810", "name": "ASB6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5W3", "map_id": "A0A3Q1M5W3", "name": "TULP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075739", "map_id": "ENSBTAT00000075739", "name": "TULP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJ12", "map_id": "E1BJ12", "name": "ASB13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025032", "map_id": "ENSBTAT00000025032", "name": "ASB13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTH7", "map_id": "F1MTH7", "name": "NEURL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001270", "map_id": "ENSBTAT00000001270", "name": "NEURL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N349", "map_id": "F1N349", "name": "ASB18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002623", "map_id": "ENSBTAT00000002623", "name": "ASB18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKN8", "map_id": "E1BKN8", "name": "SOCS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023144", "map_id": "ENSBTAT00000023144", "name": "SOCS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBH6", "map_id": "A7MBH6", "name": "ANKRD9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044628", "map_id": "ENSBTAT00000044628", "name": "ANKRD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ71", "map_id": "A0A452DJ71", "name": "ASB11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038842", "map_id": "ENSBTAT00000038842", "name": "ASB11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "H7BWV6", "map_id": "H7BWV6", "name": "ASB12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009484", "map_id": "ENSBTAT00000009484", "name": "ASB12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJ53", "map_id": "Q2HJ53", "name": "CISH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030652", "map_id": "ENSBTAT00000030652", "name": "CISH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCM1", "map_id": "E1BCM1", "name": "SPSB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069213", "map_id": "ENSBTAT00000069213", "name": "SPSB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9S2", "map_id": "E1B9S2", "name": "ASB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013884", "map_id": "ENSBTAT00000013884", "name": "ASB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEH6", "map_id": "E1BEH6", "name": "ASB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004378", "map_id": "ENSBTAT00000004378", "name": "ASB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKE5", "map_id": "E1BKE5", "name": "ASB9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064207", "map_id": "ENSBTAT00000064207", "name": "ASB9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087990", "map_id": "none", "name": "NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087869", "map_id": "Q1RMW1", "name": "UBE2F", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10087848", "map_id": "none", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075935", "map_id": "E1BJ64", "name": "NEDD8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10087835", "map_id": "none", "name": "UBA3:NAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MJI4", "map_id": "A0A3Q1MJI4", "name": "UBA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077128", "map_id": "ENSBTAT00000077128", "name": "UBA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8X4", "map_id": "E1B8X4", "name": "NAE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013367", "map_id": "ENSBTAT00000013367", "name": "NAE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087845", "map_id": "none", "name": "NEDD8-UBA3:NAE1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10087883", "map_id": "none", "name": "Transfer of NEDD8 to AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087871", "map_id": "none", "name": "AcM-UBE2F:NEDD8-UBA3:NAE1:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087880", "map_id": "none", "name": "NEDD8-AcM-UBE2F", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10087885", "map_id": "none", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087850", "map_id": "none", "name": "NEDD8-UBA3:NAE1:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10087852", "map_id": "none", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10088734", "map_id": "none", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088730", "map_id": "A7MBJ5", "name": "CAND1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000013112", "map_id": "ENSBTAT00000013112", "name": "CAND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088728", "map_id": "none", "name": "RBX1:CUL4:DDB1:DCAFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LKZ4", "map_id": "A0A3Q1LKZ4", "name": "CUL4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072958", "map_id": "ENSBTAT00000072958", "name": "CUL4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MNL1", "map_id": "A0A3Q1MNL1", "name": "CUL4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086637", "map_id": "ENSBTAT00000086637", "name": "CUL4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ09", "map_id": "A0A452DJ09", "name": "DDB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028740", "map_id": "ENSBTAT00000028740", "name": "DDB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32L87", "map_id": "Q32L87", "name": "DCAF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004550", "map_id": "ENSBTAT00000004550", "name": "DCAF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYV7", "map_id": "F1MYV7", "name": "DCAF10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019879", "map_id": "ENSBTAT00000019879", "name": "DCAF10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVI8", "map_id": "F1MVI8", "name": "DCAF13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028594", "map_id": "ENSBTAT00000028594", "name": "DCAF13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPL4", "map_id": "A0A3Q1LPL4", "name": "WDTC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070605", "map_id": "ENSBTAT00000070605", "name": "WDTC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXE6", "map_id": "G3MXE6", "name": "DCAF16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015886", "map_id": "ENSBTAT00000015886", "name": "DCAF16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMD0", "map_id": "E1BMD0", "name": "DCAF17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010105", "map_id": "ENSBTAT00000010105", "name": "DCAF17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MY43", "map_id": "A0A3Q1MY43", "name": "DCAF5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086238", "map_id": "ENSBTAT00000086238", "name": "DCAF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LT78", "map_id": "A0A3Q1LT78", "name": "DCAF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084712", "map_id": "ENSBTAT00000084712", "name": "DCAF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9A9", "map_id": "Q5E9A9", "name": "DDA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022696", "map_id": "ENSBTAT00000022696", "name": "DDA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3H0", "map_id": "F1N3H0", "name": "DCAF8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086437", "map_id": "ENSBTAT00000086437", "name": "DCAF8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088732", "map_id": "none", "name": "CRL4 E3 ubiquitin ligase:CAND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A7MBJ5", "map_id": "A7MBJ5", "name": "CAND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087825", "map_id": "none", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075937", "map_id": "none", "name": "UCHL3,SENP8:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MIW5", "map_id": "A0A3Q1MIW5", "name": "SENP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079440", "map_id": "ENSBTAT00000079440", "name": "SENP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075927", "map_id": "A0A3Q1MIW5", "name": "SENP8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10088688", "map_id": "none", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10076087", "map_id": "A7MBJ5", "name": "CAND1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088684", "map_id": "none", "name": "CRL E3 ubiquitin ligases", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QPV4", "map_id": "A6QPV4", "name": "LRR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006480", "map_id": "ENSBTAT00000006480", "name": "LRR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RM5", "map_id": "Q29RM5", "name": "FEM1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004519", "map_id": "ENSBTAT00000004519", "name": "FEM1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N162", "map_id": "F1N162", "name": "FEM1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011028", "map_id": "ENSBTAT00000011028", "name": "FEM1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB89", "map_id": "A7MB89", "name": "FEM1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011464", "map_id": "ENSBTAT00000011464", "name": "FEM1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1L9", "map_id": "A0A3Q1N1L9", "name": "FBXL19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073772", "map_id": "ENSBTAT00000073772", "name": "FBXL19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58D00", "map_id": "Q58D00", "name": "FBXW2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085937", "map_id": "ENSBTAT00000085937", "name": "FBXW2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHW1", "map_id": "A0A452DHW1", "name": "FBXL21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003178", "map_id": "ENSBTAT00000003178", "name": "FBXL21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MN48", "map_id": "A0A3Q1MN48", "name": "FBXW5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078511", "map_id": "ENSBTAT00000078511", "name": "FBXW5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKK2", "map_id": "A5PKK2", "name": "FBXL16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052368", "map_id": "ENSBTAT00000052368", "name": "FBXL16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK68", "map_id": "E1BK68", "name": "FBXO41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016959", "map_id": "ENSBTAT00000016959", "name": "FBXO41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6PQR5", "map_id": "F6PQR5", "name": "FBXL18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046646", "map_id": "ENSBTAT00000046646", "name": "FBXL18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBH8", "map_id": "A7MBH8", "name": "FBXO44", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086266", "map_id": "ENSBTAT00000086266", "name": "FBXO44", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNU6", "map_id": "A0A3Q1LNU6", "name": "FBXL14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085125", "map_id": "ENSBTAT00000085125", "name": "FBXL14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KHT6", "map_id": "Q2KHT6", "name": "FBXO32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021554", "map_id": "ENSBTAT00000021554", "name": "FBXO32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI01", "map_id": "A0A452DI01", "name": "FBXL15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003249", "map_id": "ENSBTAT00000003249", "name": "FBXL15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N1C5", "map_id": "F1N1C5", "name": "FBXO40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019285", "map_id": "ENSBTAT00000019285", "name": "FBXO40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N019", "map_id": "F1N019", "name": "FBXL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004177", "map_id": "ENSBTAT00000004177", "name": "FBXL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDP9", "map_id": "A0A3Q1MDP9", "name": "LOC789309", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067912", "map_id": "ENSBTAT00000067912", "name": "LOC789309", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCW5", "map_id": "A0A3Q1MCW5", "name": "FBXL13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083919", "map_id": "ENSBTAT00000083919", "name": "FBXL13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQM8", "map_id": "A0A3Q1LQM8", "name": "FBXO31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080785", "map_id": "ENSBTAT00000080785", "name": "FBXO31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB09", "map_id": "A7MB09", "name": "SKP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018036", "map_id": "ENSBTAT00000018036", "name": "SKP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MLW5", "map_id": "A0A3Q1MLW5", "name": "FBXO21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080771", "map_id": "ENSBTAT00000080771", "name": "FBXO21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP22", "map_id": "A6QP22", "name": "FBXL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025095", "map_id": "ENSBTAT00000025095", "name": "FBXL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJX0", "map_id": "A5PJX0", "name": "FBXO22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003665", "map_id": "ENSBTAT00000003665", "name": "FBXO22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9Q3", "map_id": "E1B9Q3", "name": "FBXO11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001868", "map_id": "ENSBTAT00000001868", "name": "FBXO11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LFJ4", "map_id": "A0A3Q1LFJ4", "name": "LMO7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086616", "map_id": "ENSBTAT00000086616", "name": "LMO7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIC0", "map_id": "A0A452DIC0", "name": "FBXO15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012776", "map_id": "ENSBTAT00000012776", "name": "FBXO15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDA7", "map_id": "F1MDA7", "name": "FBXO7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027498", "map_id": "ENSBTAT00000027498", "name": "FBXO7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M118", "map_id": "A0A3Q1M118", "name": "FBXW11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075176", "map_id": "ENSBTAT00000075176", "name": "FBXW11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSC9", "map_id": "F1MSC9", "name": "FBXO10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082146", "map_id": "ENSBTAT00000082146", "name": "FBXO10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M680", "map_id": "A0A3Q1M680", "name": "FBXW12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080715", "map_id": "ENSBTAT00000080715", "name": "FBXW12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIA2", "map_id": "A0A452DIA2", "name": "FBXL22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011600", "map_id": "ENSBTAT00000011600", "name": "FBXL22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGE6", "map_id": "E1BGE6", "name": "FBXW8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050675", "map_id": "ENSBTAT00000050675", "name": "FBXW8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QK6", "map_id": "Q17QK6", "name": "FBXO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009501", "map_id": "ENSBTAT00000009501", "name": "FBXO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLX8", "map_id": "F1MLX8", "name": "TRIM16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003367", "map_id": "ENSBTAT00000003367", "name": "TRIM16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088686", "map_id": "none", "name": "CRL E3 ubiquitin ligase:CAND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10088787", "map_id": "none", "name": "CUL9:RBX1 ubiquitinates BIRC5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10088761", "map_id": "Q6J1J1", "name": "BIRC5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000018046", "map_id": "ENSBTAT00000018046", "name": "BIRC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088764", "map_id": "Q6J1J1", "name": "BIRC5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088774", "map_id": "none", "name": "NEDD8-CUL9:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BM39", "map_id": "E1BM39", "name": "CUL9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026522", "map_id": "ENSBTAT00000026522", "name": "CUL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088785", "map_id": "none", "name": "NEDD8-CUL9:RBX1:CUL7:CCDC8:OBSL1", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6R7X9", "map_id": "F6R7X9", "name": "CCDC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024194", "map_id": "ENSBTAT00000024194", "name": "CCDC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK00", "map_id": "E1BK00", "name": "CUL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061262", "map_id": "ENSBTAT00000061262", "name": "CUL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088807", "map_id": "none", "name": "COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10088802", "map_id": "none", "name": "NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10088804", "map_id": "none", "name": "CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10084815", "map_id": "none", "name": "COP9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1ME43", "map_id": "A0A3Q1ME43", "name": "GPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071522", "map_id": "ENSBTAT00000071522", "name": "GPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X736", "map_id": "G3X736", "name": "COPS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025677", "map_id": "ENSBTAT00000025677", "name": "COPS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QE33", "map_id": "F6QE33", "name": "COPS7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014754", "map_id": "ENSBTAT00000014754", "name": "COPS7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI56", "map_id": "Q2KI56", "name": "COPS7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069661", "map_id": "ENSBTAT00000069661", "name": "COPS7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZA0", "map_id": "Q3SZA0", "name": "COPS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009128", "map_id": "ENSBTAT00000009128", "name": "COPS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBP8", "map_id": "F1MBP8", "name": "COPS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003609", "map_id": "ENSBTAT00000003609", "name": "COPS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FV74", "map_id": "A4FV74", "name": "COPS8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007696", "map_id": "ENSBTAT00000007696", "name": "COPS8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075942", "map_id": "none", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075933", "map_id": "none", "name": "UCHL3,SENP8:NEDD8(1-88)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075939", "map_id": "E1BJ64", "name": "NEDD8(77-88)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10038457", "map_id": "none", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8855657", "map_id": "CHEBI:15935", "name": "N-acetylglucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855661", "map_id": "CHEBI:24275", "name": "glucosaminyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_29416", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10038454", "map_id": "A6QQ24", "name": "PIGL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000017653", "map_id": "ENSBTAT00000017653", "name": "PIGL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038464", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855663", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_162872", "map_id": "CHEBI:16214", "name": "dolichyl phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855667", "map_id": "CHEBI:53058", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10038461", "map_id": "E1B9Z8", "name": "PIGV", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000012921", "map_id": "ENSBTAT00000012921", "name": "PIGV", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052665", "map_id": "none", "name": "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10052629", "map_id": "none", "name": "Core 1 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "A0A3Q1M6U9", "map_id": "A0A3Q1M6U9", "name": "MUC20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075287", "map_id": "ENSBTAT00000075287", "name": "MUC20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPY0", "map_id": "A0A3Q1LPY0", "name": "MUC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066675", "map_id": "ENSBTAT00000066675", "name": "MUC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M633", "map_id": "A0A3Q1M633", "name": "MUC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072582", "map_id": "ENSBTAT00000072582", "name": "MUC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N072", "map_id": "A0A3Q1N072", "name": "Disialyl T-antigen (MUC5AC)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071114", "map_id": "ENSBTAT00000071114", "name": "Disialyl T-antigen (MUC5AC)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5A7", "map_id": "G5E5A7", "name": "Disialyl T-antigen (MUC5B)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010897", "map_id": "ENSBTAT00000010897", "name": "Disialyl T-antigen (MUC5B)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQ52", "map_id": "A0A3Q1LQ52", "name": "Disialyl T-antigen (MUC16)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085382", "map_id": "ENSBTAT00000085382", "name": "Disialyl T-antigen (MUC16)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2T0", "map_id": "A0A3Q1M2T0", "name": "MUC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083797", "map_id": "ENSBTAT00000083797", "name": "MUC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052652", "map_id": "none", "name": "Core 2 mucins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10052662", "map_id": "none", "name": "GCNTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q7YQE1", "map_id": "Q7YQE1", "name": "GCNT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079217", "map_id": "ENSBTAT00000079217", "name": "GCNT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUB2", "map_id": "A0A3Q1MUB2", "name": "GCNT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076540", "map_id": "ENSBTAT00000076540", "name": "GCNT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052521", "map_id": "none", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10052400", "map_id": "none", "name": "Tn antigens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10052519", "map_id": "none", "name": "Core 8 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10077688", "map_id": "none", "name": "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10077681", "map_id": "none", "name": "Core 2S mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10077685", "map_id": "Q1LZD4", "name": "CHST4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000022569", "map_id": "ENSBTAT00000022569", "name": "CHST4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052461", "map_id": "none", "name": "GALNTs transfer GalNAc from UDP-GalNAc to mucins to form Tn antigens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10052377", "map_id": "none", "name": "Mucins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10052458", "map_id": "none", "name": "GALNTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MQ00", "map_id": "A0A3Q1MQ00", "name": "GALNT10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071740", "map_id": "ENSBTAT00000071740", "name": "GALNT10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M986", "map_id": "A0A3Q1M986", "name": "GALNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078875", "map_id": "ENSBTAT00000078875", "name": "GALNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPR6", "map_id": "E1BPR6", "name": "GALNT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061536", "map_id": "ENSBTAT00000061536", "name": "GALNT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDW8", "map_id": "E1BDW8", "name": "GALNT11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028329", "map_id": "ENSBTAT00000028329", "name": "GALNT11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBP1", "map_id": "E1BBP1", "name": "GALNT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHN6", "map_id": "E1BHN6", "name": "GALNT15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010847", "map_id": "ENSBTAT00000010847", "name": "GALNT15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLX6", "map_id": "A6QLX6", "name": "GALNT12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077005", "map_id": "ENSBTAT00000077005", "name": "GALNT12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKQ9", "map_id": "E1BKQ9", "name": "GALNT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023104", "map_id": "ENSBTAT00000023104", "name": "GALNT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q07537", "map_id": "Q07537", "name": "GALNT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081582", "map_id": "ENSBTAT00000081582", "name": "GALNT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LM69", "map_id": "A0A3Q1LM69", "name": "GALNT14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087139", "map_id": "ENSBTAT00000087139", "name": "GALNT14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QA59", "map_id": "F6QA59", "name": "GALNT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023106", "map_id": "ENSBTAT00000023106", "name": "GALNT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052716", "map_id": "none", "name": "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10052569", "map_id": "none", "name": "Core 3 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10052713", "map_id": "none", "name": "Core 4 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10052656", "map_id": "Q7YQE1", "name": "GCNT3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10052606", "map_id": "none", "name": "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10052603", "map_id": "none", "name": "B3GNTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MPZ8", "map_id": "A0A3Q1MPZ8", "name": "B3GNT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078680", "map_id": "ENSBTAT00000078680", "name": "B3GNT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YY64", "map_id": "A7YY64", "name": "B3GNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024024", "map_id": "ENSBTAT00000024024", "name": "B3GNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGN7", "map_id": "F1MGN7", "name": "B3GNT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063600", "map_id": "ENSBTAT00000063600", "name": "B3GNT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LX89", "map_id": "A0A3Q1LX89", "name": "B3GNT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084108", "map_id": "ENSBTAT00000084108", "name": "B3GNT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVP5", "map_id": "A0A3Q1LVP5", "name": "B3GNT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079485", "map_id": "ENSBTAT00000079485", "name": "B3GNT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSS4", "map_id": "F1MSS4", "name": "B3GNT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005494", "map_id": "ENSBTAT00000005494", "name": "B3GNT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VC83", "map_id": "Q0VC83", "name": "B3GNT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021344", "map_id": "ENSBTAT00000021344", "name": "B3GNT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054575", "map_id": "none", "name": "Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10054573", "map_id": "none", "name": "Sialyl-2,6 T antigens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10054766", "map_id": "none", "name": "ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10054701", "map_id": "none", "name": "Sialyl-2,3 T antigens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10054759", "map_id": "none", "name": "Disialyl T antigens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10054763", "map_id": "G3N3B2", "name": "ST6GALNAC4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10054722", "map_id": "none", "name": "ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10054773", "map_id": "none", "name": "GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10054770", "map_id": "A0A3Q1LRX1", "name": "ST6GALNAC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10054550", "map_id": "none", "name": "Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10054548", "map_id": "none", "name": "Sialyl Tn antigens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10052496", "map_id": "none", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10052494", "map_id": "none", "name": "Core 5 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10061538", "map_id": "none", "name": "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061535", "map_id": "none", "name": "C1GALT1:C1GALT1C1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q0VC84", "map_id": "Q0VC84", "name": "C1GALT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068688", "map_id": "ENSBTAT00000068688", "name": "C1GALT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX46", "map_id": "Q3SX46", "name": "C1GALT1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028542", "map_id": "ENSBTAT00000028542", "name": "C1GALT1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052546", "map_id": "none", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10052544", "map_id": "none", "name": "Core 6 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10052690", "map_id": "none", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10052688", "map_id": "none", "name": "Core 7 mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10076773", "map_id": "none", "name": "A4GNT transfers GlcNAc to core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10076766", "map_id": "none", "name": "Core 2a mucins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10076770", "map_id": "E1B9E0", "name": "A4GNT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000001899", "map_id": "ENSBTAT00000001899", "name": "A4GNT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070145", "map_id": "none", "name": "B3GALTL transfers glucose to O-fucosyl-proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10070064", "map_id": "none", "name": "O-fuc-proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1MXR3", "map_id": "F1MXR3", "name": "ADAMTSL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081541", "map_id": "ENSBTAT00000081541", "name": "ADAMTSL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVP0", "map_id": "F1MVP0", "name": "ADAMTS13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020085", "map_id": "ENSBTAT00000020085", "name": "ADAMTS13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MX27", "map_id": "A0A3Q1MX27", "name": "ADAMTS7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086844", "map_id": "ENSBTAT00000086844", "name": "ADAMTS7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2R9", "map_id": "A0A3Q1M2R9", "name": "CFP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085538", "map_id": "ENSBTAT00000085538", "name": "CFP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK41", "map_id": "E1BK41", "name": "ADAMTSL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061071", "map_id": "ENSBTAT00000061071", "name": "ADAMTSL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_173594", "map_id": "CHEBI:18066", "name": "UDP-Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_158602", "map_id": "CHEBI:17659", "name": "UDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10070138", "map_id": "none", "name": "glc-fuc-proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10070142", "map_id": "F1MKA0", "name": "B3GLCT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000047526", "map_id": "ENSBTAT00000047526", "name": "B3GLCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077897", "map_id": "none", "name": "FN3KRP phosphorylates PsiAm, RibAm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788865", "map_id": "none", "name": "PsiAm, RibAm", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:87176", "map_id": "CHEBI:87176", "name": "CHEBI:87176", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:87177", "map_id": "CHEBI:87177", "name": "CHEBI:87177", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6788858", "map_id": "none", "name": "PsiAm3P, RibAm3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:87180", "map_id": "CHEBI:87180", "name": "CHEBI:87180", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:87179", "map_id": "CHEBI:87179", "name": "CHEBI:87179", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077894", "map_id": "Q0P592", "name": "FN3KRP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020456", "map_id": "ENSBTAT00000020456", "name": "FN3KRP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077883", "map_id": "none", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6788753", "map_id": "CHEBI:86019", "name": "S-FARN-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788758", "map_id": "CHEBI:87167", "name": "S-FARN-CME", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10038408", "map_id": "none", "name": "Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10038406", "map_id": "none", "name": "pro-factor X", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A452DIP8", "map_id": "A0A452DIP8", "name": "F10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021789", "map_id": "ENSBTAT00000021789", "name": "F10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038394", "map_id": "none", "name": "pro-factor X", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10038416", "map_id": "none", "name": "Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10038412", "map_id": "P22457", "name": "F7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000009746", "map_id": "ENSBTAT00000009746", "name": "F7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038414", "map_id": "P22457", "name": "F7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10038438", "map_id": "none", "name": "Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10038436", "map_id": "A0A452DI66", "name": "F2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10038384", "map_id": "A0A452DI66", "name": "F2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10043698", "map_id": "none", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043683", "map_id": "none", "name": "Dhp-K50-EIF5A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q6EWQ7", "map_id": "Q6EWQ7", "name": "EIF5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084447", "map_id": "ENSBTAT00000084447", "name": "EIF5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN49", "map_id": "F1MN49", "name": "EIF5A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079770", "map_id": "ENSBTAT00000079770", "name": "EIF5A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_204628", "map_id": "CHEBI:15725", "name": "1,3-diaminopropane", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_204635", "map_id": "CHEBI:16610", "name": "SPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043689", "map_id": "none", "name": "EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043695", "map_id": "none", "name": "DHPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q6EWQ6", "map_id": "Q6EWQ6", "name": "DHPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008200", "map_id": "ENSBTAT00000008200", "name": "DHPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043717", "map_id": "none", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043708", "map_id": "none", "name": "Hyp-K50-EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043714", "map_id": "none", "name": "DOHH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC53", "map_id": "Q0VC53", "name": "DOHH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006935", "map_id": "ENSBTAT00000006935", "name": "DOHH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060109", "map_id": "none", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060079", "map_id": "none", "name": "ARS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1N665", "map_id": "F1N665", "name": "ARSG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014061", "map_id": "ENSBTAT00000014061", "name": "ARSG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148F3", "map_id": "Q148F3", "name": "ARSK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026877", "map_id": "ENSBTAT00000026877", "name": "ARSK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZ44", "map_id": "A0A3Q1LZ44", "name": "STS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081469", "map_id": "ENSBTAT00000081469", "name": "STS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLZ3", "map_id": "A6QLZ3", "name": "ARSB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010988", "map_id": "ENSBTAT00000010988", "name": "ARSB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2T7", "map_id": "G3N2T7", "name": "ARSH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072310", "map_id": "ENSBTAT00000072310", "name": "ARSH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LGQ6", "map_id": "A0A3Q1LGQ6", "name": "ARSD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080500", "map_id": "ENSBTAT00000080500", "name": "ARSD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIN3", "map_id": "E1BIN3", "name": "ARSI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017050", "map_id": "ENSBTAT00000017050", "name": "ARSI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7J7", "map_id": "A5D7J7", "name": "ARSL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050377", "map_id": "ENSBTAT00000050377", "name": "ARSL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKH3", "map_id": "E1BKH3", "name": "ARSJ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023672", "map_id": "ENSBTAT00000023672", "name": "ARSJ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1663154", "map_id": "CHEBI:16136", "name": "H2S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060106", "map_id": "none", "name": "active ARS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10060045", "map_id": "Q0P5L5", "name": "SUMF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000055237", "map_id": "ENSBTAT00000055237", "name": "SUMF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091630", "map_id": "none", "name": "TPST1,2 transfer SO4(2-) from PAPS to FVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10091620", "map_id": "G5E5W1", "name": "F8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10091628", "map_id": "G5E5W1", "name": "F8", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10088614", "map_id": "Q08DH2", "name": "TPST1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000000502", "map_id": "ENSBTAT00000000502", "name": "TPST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071579", "map_id": "none", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071569", "map_id": "Q3SYU2", "name": "EEF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071572", "map_id": "Q3SYU2", "name": "EEF2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071576", "map_id": "Q5E982", "name": "DPH5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025327", "map_id": "ENSBTAT00000025327", "name": "DPH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071566", "map_id": "none", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071559", "map_id": "Q3SYU2", "name": "EEF2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31633", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071563", "map_id": "Q2HJF5", "name": "DPH6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000055382", "map_id": "ENSBTAT00000055382", "name": "DPH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066409", "map_id": "none", "name": "SENP1,2,5 proteolytically process SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066405", "map_id": "Q17QV3", "name": "SUMO3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000023029", "map_id": "ENSBTAT00000023029", "name": "SUMO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066407", "map_id": "Q17QV3", "name": "SUMO3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066369", "map_id": "none", "name": "SENP1,2,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BAI5", "map_id": "E1BAI5", "name": "SENP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002296", "map_id": "ENSBTAT00000002296", "name": "SENP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTU0", "map_id": "A0A3Q1MTU0", "name": "SENP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080821", "map_id": "ENSBTAT00000080821", "name": "SENP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFX1", "map_id": "A0A3Q1MFX1", "name": "SENP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078136", "map_id": "ENSBTAT00000078136", "name": "SENP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066380", "map_id": "none", "name": "SENP1,2,5 proteolytically process SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066376", "map_id": "A0A3Q1M927", "name": "SUMO2(1-95)", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000081472", "map_id": "ENSBTAT00000081472", "name": "SUMO2(1-95)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066378", "map_id": "A0A3Q1M927", "name": "SUMO2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10066372", "map_id": "none", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066355", "map_id": "none", "name": "Homologues of SUMO1(2-101)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077406", "map_id": "none", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056739", "map_id": "Q2TA10", "name": "UBE2D1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10077402", "map_id": "none", "name": "OTUB1,(OTUB2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3T0Y1", "map_id": "Q3T0Y1", "name": "OTUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005174", "map_id": "ENSBTAT00000005174", "name": "OTUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077404", "map_id": "none", "name": "OTUB1,(OTUB2):UBE2D1,ESR1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076001", "map_id": "none", "name": "OTUD7B,TNFAIP3 deubiquitinate TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075996", "map_id": "none", "name": "OTUD7B,TNFAIP3,ZRANB1:K48polyUb-TRAF6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B9S7", "map_id": "E1B9S7", "name": "OTUD7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021435", "map_id": "ENSBTAT00000021435", "name": "OTUD7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075998", "map_id": "none", "name": "OTUD7B,TNFAIP3,ZRANB1:TRAF6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10085345", "map_id": "none", "name": "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085342", "map_id": "none", "name": "OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075952", "map_id": "none", "name": "TNFAIP3 (A20) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075944", "map_id": "none", "name": "TNFAIP3:RIPK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075949", "map_id": "none", "name": "TNFAIP3:K48polyUb-RIPK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075984", "map_id": "none", "name": "TNIPs bind TNFAIP3 (A20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037956", "map_id": "A0A3Q1NKI9", "name": "TNFAIP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075980", "map_id": "none", "name": "TNIPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N2J6", "map_id": "G3N2J6", "name": "TNIP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064143", "map_id": "ENSBTAT00000064143", "name": "TNIP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKS3", "map_id": "E1BKS3", "name": "TNIP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020124", "map_id": "ENSBTAT00000020124", "name": "TNIP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPJ2", "map_id": "A0A3S5ZPJ2", "name": "TNIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016836", "map_id": "ENSBTAT00000016836", "name": "TNIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075982", "map_id": "none", "name": "TNFAIP3:TNIPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084931", "map_id": "none", "name": "OTUD7A hydrolyses K11diUb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075838", "map_id": "none", "name": "K11-Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10084928", "map_id": "F1MZ13", "name": "OTUD7A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009023", "map_id": "ENSBTAT00000009023", "name": "OTUD7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075970", "map_id": "none", "name": "OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075966", "map_id": "none", "name": "RNF128,TRAF3,TRAF6,RHOA,TP53", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P67939", "map_id": "P67939", "name": "TP53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001420", "map_id": "ENSBTAT00000001420", "name": "TP53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075962", "map_id": "none", "name": "OTUB1,(OTUB2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075968", "map_id": "none", "name": "OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075989", "map_id": "none", "name": "TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075986", "map_id": "none", "name": "TNFAIP3:K63polyUb-RIPK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077371", "map_id": "none", "name": "USP13 binds SIAH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077367", "map_id": "E1BMF7", "name": "USP13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000061390", "map_id": "ENSBTAT00000061390", "name": "USP13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054896", "map_id": "F1MBM6", "name": "SIAH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000044404", "map_id": "ENSBTAT00000044404", "name": "SIAH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077369", "map_id": "none", "name": "SIAH2:USP13", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MBM6", "map_id": "F1MBM6", "name": "SIAH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMF7", "map_id": "E1BMF7", "name": "USP13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077339", "map_id": "none", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077335", "map_id": "F1MUD4", "name": "USP19", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025198", "map_id": "ENSBTAT00000025198", "name": "USP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077337", "map_id": "none", "name": "USP19:HIF1A,BIRC2,BIRC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MUD4", "map_id": "F1MUD4", "name": "USP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075550", "map_id": "none", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075418", "map_id": "none", "name": "USP7:PolyUb-TP53,PolyUb-MDM2,PolyUb-MDM4,PolyUb-FOXO4,PolyUb-PTEN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6QLP0", "map_id": "A6QLP0", "name": "FOXO4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006418", "map_id": "ENSBTAT00000006418", "name": "FOXO4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075422", "map_id": "none", "name": "USP7:TP53,MDM2,MDM4,FOXO4,PTEN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075547", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075902", "map_id": "none", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075897", "map_id": "none", "name": "USP16,USP21:Ub-histone H2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MY85", "map_id": "A0A3Q1MY85", "name": "USP16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087113", "map_id": "ENSBTAT00000087113", "name": "USP16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075899", "map_id": "none", "name": "USP16,USP22:Histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077393", "map_id": "none", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077388", "map_id": "none", "name": "USP17:K63polyUb-SUDS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LQ57", "map_id": "A0A3Q1LQ57", "name": "SUDS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079478", "map_id": "ENSBTAT00000079478", "name": "SUDS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MC38", "map_id": "A0A3Q1MC38", "name": "USP17L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079399", "map_id": "ENSBTAT00000079399", "name": "USP17L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MME1", "map_id": "A0A3Q1MME1", "name": "LOC790134", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043704", "map_id": "ENSBTAT00000043704", "name": "LOC790134", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAX7", "map_id": "A0A3Q1MAX7", "name": "LOC112446467", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031172", "map_id": "ENSBTAT00000031172", "name": "LOC112446467", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075488", "map_id": "none", "name": "K63polyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10077390", "map_id": "none", "name": "USP17:SUDS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075891", "map_id": "none", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075886", "map_id": "none", "name": "USP5:PolyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N3P2", "map_id": "F1N3P2", "name": "USP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075888", "map_id": "none", "name": "USP5:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077363", "map_id": "none", "name": "USP11 deubiquitinates NFKBIA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077358", "map_id": "none", "name": "USP11:PolyUb-NFKBIA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A5PKF9", "map_id": "A5PKF9", "name": "USP11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022310", "map_id": "ENSBTAT00000022310", "name": "USP11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077360", "map_id": "none", "name": "USP11:NFKBIA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10075884", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077331", "map_id": "none", "name": "USP44 deubiquitinates CDC20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077326", "map_id": "none", "name": "USP44:PolyUb-CDC20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MRW5", "map_id": "F1MRW5", "name": "CDC20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077512", "map_id": "ENSBTAT00000077512", "name": "CDC20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLZ0", "map_id": "E1BLZ0", "name": "USP44", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026571", "map_id": "ENSBTAT00000026571", "name": "USP44", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077328", "map_id": "none", "name": "USP44:CDC20", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075561", "map_id": "none", "name": "USP10,USP24,USP42 deubiquitinate TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075556", "map_id": "none", "name": "USP10,USP24,USP42:PolyUb-TP53", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A452DHT6", "map_id": "A0A452DHT6", "name": "USP42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000967", "map_id": "ENSBTAT00000000967", "name": "USP42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075558", "map_id": "none", "name": "USP10,USP24,USP42:TP53", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077034", "map_id": "none", "name": "USP25 deubiquitinates DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077029", "map_id": "none", "name": "USP25:PolyUb-DDX58", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MMX0", "map_id": "A0A3Q1MMX0", "name": "USP25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075352", "map_id": "ENSBTAT00000075352", "name": "USP25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKU1", "map_id": "F1MKU1", "name": "DDX58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061377", "map_id": "ENSBTAT00000061377", "name": "DDX58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077031", "map_id": "none", "name": "USP25:DDX58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077292", "map_id": "none", "name": "USP30 deubiquitinates Ub-MOM proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10077171", "map_id": "none", "name": "USP30:PolyUb-MOM proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "F1MSB6", "map_id": "F1MSB6", "name": "USP30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029564", "map_id": "ENSBTAT00000029564", "name": "USP30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077189", "map_id": "none", "name": "USP30:MOM proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10077289", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10077070", "map_id": "none", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077061", "map_id": "none", "name": "USP17:PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BJZ0", "map_id": "E1BJZ0", "name": "IFIH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010703", "map_id": "ENSBTAT00000010703", "name": "IFIH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077067", "map_id": "none", "name": "USP17L1,USP17L2:RCE1, CDC25A, DDX58, IFIH1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075808", "map_id": "none", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075801", "map_id": "none", "name": "USP3,SAGA:Ub-histone H2A, Ub-histone H2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N5C0", "map_id": "A0A3Q1N5C0", "name": "USP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087295", "map_id": "ENSBTAT00000087295", "name": "USP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EAE2", "map_id": "Q5EAE2", "name": "TADA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047754", "map_id": "ENSBTAT00000047754", "name": "TADA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0C8Z3", "map_id": "P0C8Z3", "name": "USP22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011818", "map_id": "ENSBTAT00000011818", "name": "USP22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJW1", "map_id": "A5PJW1", "name": "TAF10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000926", "map_id": "ENSBTAT00000000926", "name": "TAF10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BP59", "map_id": "E1BP59", "name": "KAT2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061193", "map_id": "ENSBTAT00000061193", "name": "KAT2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKJ5", "map_id": "E1BKJ5", "name": "TRRAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009365", "map_id": "ENSBTAT00000009365", "name": "TRRAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E6P9", "map_id": "G5E6P9", "name": "TADA2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013438", "map_id": "ENSBTAT00000013438", "name": "TADA2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075805", "map_id": "none", "name": "USP3,SAGA:Histone H2A,Histone H2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077379", "map_id": "none", "name": "USP13 binds UFD1L:SKP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077375", "map_id": "none", "name": "UFD1L:SKP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N3E8", "map_id": "A0A3Q1N3E8", "name": "UFD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080740", "map_id": "ENSBTAT00000080740", "name": "UFD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077373", "map_id": "E1BMF7", "name": "USP13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10077377", "map_id": "none", "name": "USP13:UFD1L:SKP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077349", "map_id": "none", "name": "USP19 deubiquitinates RNF123", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077344", "map_id": "none", "name": "USP19:K63polyUb-RNF123", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BL26", "map_id": "E1BL26", "name": "RNF123", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045376", "map_id": "ENSBTAT00000045376", "name": "RNF123", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077346", "map_id": "none", "name": "USP19:RNF123", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077317", "map_id": "none", "name": "USP28 deubiquitinates CLSPN and MYC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077308", "map_id": "none", "name": "USP28:PolyUb-CLSPN, PolyUb-MYC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LF69", "map_id": "A0A3Q1LF69", "name": "CLSPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074281", "map_id": "ENSBTAT00000074281", "name": "CLSPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAA7", "map_id": "A0A3Q1MAA7", "name": "USP28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081720", "map_id": "ENSBTAT00000081720", "name": "USP28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077314", "map_id": "none", "name": "USP28:CLSPN,MYC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075374", "map_id": "none", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075366", "map_id": "Q29RK4", "name": "RAD23B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000002506", "map_id": "ENSBTAT00000002506", "name": "RAD23B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075370", "map_id": "A6H799", "name": "ATXN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000007611", "map_id": "ENSBTAT00000007611", "name": "ATXN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075372", "map_id": "none", "name": "ATXN3:RAD23", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6H799", "map_id": "A6H799", "name": "ATXN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RK4", "map_id": "Q29RK4", "name": "RAD23B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075397", "map_id": "none", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10075394", "map_id": "none", "name": "ATXN3,ATXN3L,JOSD1,JOSD2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MF75", "map_id": "A0A3Q1MF75", "name": "LOC512323", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067648", "map_id": "ENSBTAT00000067648", "name": "LOC512323", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4J1", "map_id": "A0A3Q1M4J1", "name": "ATXN3L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073722", "map_id": "ENSBTAT00000073722", "name": "ATXN3L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ME39", "map_id": "F1ME39", "name": "JOSD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008984", "map_id": "ENSBTAT00000008984", "name": "JOSD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086303", "map_id": "none", "name": "METTL22 transfers 3xCH3 from 3xAdoMet to KIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086293", "map_id": "E1BND1", "name": "KIN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000061405", "map_id": "ENSBTAT00000061405", "name": "KIN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086296", "map_id": "E1BND1", "name": "KIN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10086300", "map_id": "A0A3Q1MHI2", "name": "METTL22", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000084035", "map_id": "ENSBTAT00000084035", "name": "METTL22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086319", "map_id": "none", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038086", "map_id": "P68103", "name": "EEF1A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000087016", "map_id": "ENSBTAT00000087016", "name": "EEF1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086312", "map_id": "P68103", "name": "EEF1A1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086316", "map_id": "A0A3Q1MY73", "name": "EEF1AKMT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000085737", "map_id": "ENSBTAT00000085737", "name": "EEF1AKMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086286", "map_id": "none", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10086279", "map_id": "P68103", "name": "EEF1A1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086283", "map_id": "A0A3Q1MK29", "name": "EEF1AKMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000065836", "map_id": "ENSBTAT00000065836", "name": "EEF1AKMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077744", "map_id": "none", "name": "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037000", "map_id": "A0A3Q1MR28", "name": "CALM1", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077737", "map_id": "A0A3Q1MR28", "name": "Me3K115-CALM1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077741", "map_id": "A7YWN4", "name": "CAMKMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000046124", "map_id": "ENSBTAT00000046124", "name": "CAMKMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083231", "map_id": "none", "name": "PDCL promotes formation of G-beta:G-gamma heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037407", "map_id": "none", "name": "G-protein gamma subunit", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10083225", "map_id": "none", "name": "p-S18,S19,S20,S25-PDCL:G-protein beta 1-4 subunit", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2HJA9", "map_id": "Q2HJA9", "name": "phospho-PDCL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043370", "map_id": "ENSBTAT00000043370", "name": "phospho-PDCL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKD6", "map_id": "A5PKD6", "name": "GNB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083809", "map_id": "ENSBTAT00000083809", "name": "GNB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11017", "map_id": "P11017", "name": "GNB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008508", "map_id": "ENSBTAT00000008508", "name": "GNB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083229", "map_id": "none", "name": "p-S18,S19,S20,S25-PDCL:G-protein beta 1-4:gamma complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083808", "map_id": "none", "name": "G-protein alpha releases G-protein heterotrimer from PDCL ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083806", "map_id": "none", "name": "G-protein heterotrimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10083195", "map_id": "Q2HJA9", "name": "phospho-PDCL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10077947", "map_id": "none", "name": "SFTPB binds itself", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen" }, { "id": "species_10074840", "map_id": "P15781", "name": "SFTPB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "ENSBTAT00000045134", "map_id": "ENSBTAT00000045134", "name": "SFTPB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074859", "map_id": "none", "name": "SFTPB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "true" }, { "id": "P15781", "map_id": "P15781", "name": "SFTPB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088922", "map_id": "none", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10088918", "map_id": "none", "name": "SFTPD trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P35246", "map_id": "P35246", "name": "SFTPD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008579", "map_id": "ENSBTAT00000008579", "name": "SFTPD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088920", "map_id": "none", "name": "SFTPD 12mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10074686", "map_id": "none", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2133233", "compartment_display": "lamellar body membrane" }, { "id": "species_5684863", "map_id": "none", "name": "PC, PG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_1602402", "map_id": "CHEBI:17517", "name": "PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5684869", "map_id": "none", "name": "PC, PG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_80738", "compartment_display": "lamellar body", "complex": "true" }, { "id": "species_10074683", "map_id": "E1BCR1", "name": "ABCA3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2133233", "compartment_display": "lamellar body membrane", "complex": "false" }, { "id": "ENSBTAT00000019840", "map_id": "ENSBTAT00000019840", "name": "ABCA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074833", "map_id": "none", "name": "SFTPB,C, PC, PG translocate from lamellar body to extracellular region.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_80738", "compartment_display": "lamellar body" }, { "id": "species_10074821", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_80738", "compartment_display": "lamellar body", "complex": "false" }, { "id": "ENSBTAT00000016672", "map_id": "ENSBTAT00000016672", "name": "SFTPC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074817", "map_id": "none", "name": "SFTPB dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_80738", "compartment_display": "lamellar body", "complex": "true" }, { "id": "species_5686242", "map_id": "none", "name": "PC, PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10074827", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10074825", "map_id": "none", "name": "SFTPB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10074831", "map_id": "F1MV32", "name": "ADGRF5", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000035930", "map_id": "ENSBTAT00000035930", "name": "ADGRF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091120", "map_id": "none", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10075101", "map_id": "none", "name": "SFTPD 12mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10074707", "map_id": "none", "name": "CCDC59 binds TTF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074703", "map_id": "E1B9V4", "name": "TTF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000024905", "map_id": "ENSBTAT00000024905", "name": "TTF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074699", "map_id": "A5PJN1", "name": "CCDC59", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000050784", "map_id": "ENSBTAT00000050784", "name": "CCDC59", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074705", "map_id": "none", "name": "CCDC59:TTF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A5PJN1", "map_id": "A5PJN1", "name": "CCDC59", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9V4", "map_id": "E1B9V4", "name": "TTF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074869", "map_id": "none", "name": "pro-SFTPC translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10074865", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10074867", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "reaction_10075125", "map_id": "none", "name": "SFTPs translocate from extracellular region to clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10075103", "map_id": "none", "name": "CSF2RA:CSF2RB:SFTPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NJ66", "map_id": "A0A3Q1NJ66", "name": "SFTPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068360", "map_id": "ENSBTAT00000068360", "name": "SFTPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJB4", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075111", "map_id": "none", "name": "SFTPA1 18mer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "species_10075123", "map_id": "none", "name": "SFTPD 12mer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "species_10075117", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "false" }, { "id": "species_10075099", "map_id": "none", "name": "CSF2RA:CSF2RB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10075115", "map_id": "none", "name": "SFTPB dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "reaction_10091124", "map_id": "none", "name": "pro-SFTPB translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10091122", "map_id": "P15781", "name": "SFTPB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10074838", "map_id": "P15781", "name": "SFTPB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "reaction_10075095", "map_id": "none", "name": "ZDHHC2 transfers PALM from PALM-CoA to CKAP4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10075088", "map_id": "F1ME65", "name": "CKAP4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10075070", "map_id": "F1ME65", "name": "CKAP4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10075092", "map_id": "G3MXF3", "name": "ZDHHC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064000", "map_id": "ENSBTAT00000064000", "name": "ZDHHC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074857", "map_id": "none", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen" }, { "id": "species_5685882", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "species_10074844", "map_id": "P15781", "name": "SFTPB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "species_10074842", "map_id": "P15781", "name": "SFTPB", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "species_10074854", "map_id": "none", "name": "NAPSA, CTSH, PGA3-5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "true" }, { "id": "E1BJW6", "map_id": "E1BJW6", "name": "NAPSA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008917", "map_id": "ENSBTAT00000008917", "name": "NAPSA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N373", "map_id": "F1N373", "name": "PGA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019640", "map_id": "ENSBTAT00000019640", "name": "PGA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075019", "map_id": "none", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10075015", "map_id": "none", "name": "SFTPA1 18mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10075017", "map_id": "none", "name": "SFTPA1 18mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10075084", "map_id": "none", "name": "PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10075072", "map_id": "none", "name": "PALM-C100-CKAP4:SFTPAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10075082", "map_id": "none", "name": "PALM-C100-CKAP4:SFTPAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_80738", "compartment_display": "lamellar body", "complex": "true" }, { "id": "reaction_10075023", "map_id": "none", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen" }, { "id": "species_10075021", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "species_10074861", "map_id": "A0A452DJB4", "name": "SFTPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen", "complex": "false" }, { "id": "reaction_10074863", "map_id": "none", "name": "SFTPB dimer,C translocate from multivesicle body to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_3828046", "compartment_display": "multivesicular body lumen" }, { "id": "reaction_10075086", "map_id": "none", "name": "PALM-C100-CKAP4 binds SFTPAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10075105", "map_id": "none", "name": "CSF2RA:CSF2RB binds SFTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10081291", "map_id": "none", "name": "The PIDDosome activates CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081288", "map_id": "none", "name": "PIDDosome:CASP2(2-452)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G5E5N0", "map_id": "G5E5N0", "name": "PIDD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026157", "map_id": "ENSBTAT00000026157", "name": "PIDD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBQ2", "map_id": "A0A3Q1MBQ2", "name": "CRADD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071531", "map_id": "ENSBTAT00000071531", "name": "CRADD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MIB8", "map_id": "A0A3Q1MIB8", "name": "CASP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071790", "map_id": "ENSBTAT00000071790", "name": "CASP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081284", "map_id": "none", "name": "PIDDosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10043771", "map_id": "A0A3Q1MIB8", "name": "CASP2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043769", "map_id": "A0A3Q1MIB8", "name": "CASP2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081274", "map_id": "none", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081269", "map_id": "G5E5N0", "name": "PIDD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10081272", "map_id": "G5E5N0", "name": "phospho-PIDD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10074441", "map_id": "E1BEI6", "name": "phospho-ATM", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000040104", "map_id": "ENSBTAT00000040104", "name": "ATM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081293", "map_id": "none", "name": "The PIDDosome binds CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043767", "map_id": "A0A3Q1MIB8", "name": "CASP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081278", "map_id": "none", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081276", "map_id": "G5E5N0", "name": "phospho-PIDD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081286", "map_id": "none", "name": "PIDD1 associates with CRADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081282", "map_id": "A0A3Q1MBQ2", "name": "CRADD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10080457", "map_id": "none", "name": "ATM phosphorylates ZNF420", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10053725", "map_id": "none", "name": "Homologues of ZNF420", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1ML53", "map_id": "A0A3Q1ML53", "name": "ZNF607", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083153", "map_id": "ENSBTAT00000083153", "name": "ZNF607", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N3R0", "map_id": "G3N3R0", "name": "ZNF607", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MWH2", "map_id": "A0A3Q1MWH2", "name": "ZNF607", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJ74", "map_id": "F1MJ74", "name": "ZNF607", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LXQ4", "map_id": "A0A3Q1LXQ4", "name": "ZNF607", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3X9", "map_id": "F1N3X9", "name": "LOC100336984", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057355", "map_id": "ENSBTAT00000057355", "name": "LOC100336984", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080455", "map_id": "none", "name": "Homologues of p-S68-ZNF420", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10081305", "map_id": "none", "name": "STEAP3 binds BNIP3L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10081301", "map_id": "Q3T013", "name": "BNIP3L", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000033862", "map_id": "ENSBTAT00000033862", "name": "BNIP3L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052892", "map_id": "A0A3Q1LPT9", "name": "STEAP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "species_10081303", "map_id": "none", "name": "STEAP3:BNIP3L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q3T013", "map_id": "Q3T013", "name": "BNIP3L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081323", "map_id": "none", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10081319", "map_id": "none", "name": "PRELID1, PRELID3A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q32KN9", "map_id": "Q32KN9", "name": "PRELID1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006594", "map_id": "ENSBTAT00000006594", "name": "PRELID1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081309", "map_id": "Q0P5E1", "name": "TRIAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "ENSBTAT00000016994", "map_id": "ENSBTAT00000016994", "name": "TRIAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081321", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q0P5E1", "map_id": "Q0P5E1", "name": "TRIAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081326", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1500590", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_1524101", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10080738", "map_id": "none", "name": "TP53I3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10080734", "map_id": "Q0VC75", "name": "TP53I3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000004413", "map_id": "ENSBTAT00000004413", "name": "TP53I3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080736", "map_id": "none", "name": "TP53I3 Dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC75", "map_id": "Q0VC75", "name": "TP53I3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080789", "map_id": "none", "name": "TP53I3 oxidoreductase generates unstable semiquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799725", "map_id": "CHEBI:34055", "name": "1,2-Naphthoquinone", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6799726", "map_id": "CHEBI:15817", "name": "semiquinone", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056702", "map_id": "none", "name": "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29406", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056667", "map_id": "A0A3Q1MIU5", "name": "EPAS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000075132", "map_id": "ENSBTAT00000075132", "name": "EPAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29434", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056691", "map_id": "A0A3Q1MIU5", "name": "EPAS1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056699", "map_id": "none", "name": "FIH1:AscH-:Fe2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MG82", "map_id": "F1MG82", "name": "HIF1AN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000101", "map_id": "ENSBTAT00000000101", "name": "HIF1AN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056679", "map_id": "none", "name": "HIF-alpha translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056671", "map_id": "none", "name": "HIF-alpha", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MIU5", "map_id": "A0A3Q1MIU5", "name": "EPAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKG5", "map_id": "A0A3Q1MKG5", "name": "HIF3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077844", "map_id": "ENSBTAT00000077844", "name": "HIF3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056677", "map_id": "none", "name": "HIF-alpha", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056761", "map_id": "none", "name": "Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056629", "map_id": "none", "name": "hydroxyPro-HIF-alpha", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10056659", "map_id": "none", "name": "PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MBA0", "map_id": "A7MBA0", "name": "EGLN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010744", "map_id": "ENSBTAT00000010744", "name": "EGLN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2B6", "map_id": "A0A3Q1M2B6", "name": "EGLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066920", "map_id": "ENSBTAT00000066920", "name": "EGLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5X0", "map_id": "G5E5X0", "name": "LIMD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037007", "map_id": "ENSBTAT00000037007", "name": "LIMD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056685", "map_id": "none", "name": "hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056719", "map_id": "none", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056675", "map_id": "A0A3Q1MKG5", "name": "HIF3A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113671", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113685", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10056704", "map_id": "A0A3Q1MKG5", "name": "HIF3A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159942", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159939", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10056716", "map_id": "none", "name": "PHD1,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LUX2", "map_id": "A0A3Q1LUX2", "name": "EGLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072600", "map_id": "ENSBTAT00000072600", "name": "EGLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056737", "map_id": "none", "name": "Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056723", "map_id": "none", "name": "hydroxyPro-HIF-alpha", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056733", "map_id": "none", "name": "VHL:EloB,C:CUL2:RBX1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056735", "map_id": "none", "name": "hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056688", "map_id": "none", "name": "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056683", "map_id": "none", "name": "UBE2D1,2,3:Ubiquitin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10056661", "map_id": "none", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10056681", "map_id": "none", "name": "UBE2D1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056754", "map_id": "none", "name": "Nuclear VBC complex ubiquitinylates HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056747", "map_id": "none", "name": "UBE2D1,2,3:Ubiquitin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056751", "map_id": "none", "name": "ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056745", "map_id": "none", "name": "UBE2D1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056757", "map_id": "none", "name": "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056669", "map_id": "A0A3Q1MKG5", "name": "HIF3A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056627", "map_id": "A0A3Q1MKG5", "name": "HIF3A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056759", "map_id": "none", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056633", "map_id": "none", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10044776", "map_id": "none", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044772", "map_id": "none", "name": "OAZ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N021", "map_id": "F1N021", "name": "OAZ2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044965", "map_id": "ENSBTAT00000044965", "name": "OAZ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LX71", "map_id": "A0A3Q1LX71", "name": "OAZ3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079466", "map_id": "ENSBTAT00000079466", "name": "OAZ3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033775", "map_id": "P27117", "name": "ODC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000005575", "map_id": "ENSBTAT00000005575", "name": "ODC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044774", "map_id": "none", "name": "ODC:OAZ complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27117", "map_id": "P27117", "name": "ODC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044794", "map_id": "none", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044788", "map_id": "A3KMV9", "name": "AZIN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072826", "map_id": "ENSBTAT00000072826", "name": "AZIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044792", "map_id": "none", "name": "AZIN1 bound OAZ:ODC complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A3KMV9", "map_id": "A3KMV9", "name": "AZIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044784", "map_id": "none", "name": "NQO1 interaction with ODC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044780", "map_id": "A0A3Q1MK02", "name": "NQO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000079752", "map_id": "ENSBTAT00000079752", "name": "NQO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044782", "map_id": "none", "name": "ODC:NQO1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MK02", "map_id": "A0A3Q1MK02", "name": "NQO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047519", "map_id": "none", "name": "Rap1 signal termination by Rap1GAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047512", "map_id": "none", "name": "Rap1 GTPase-activating proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MI55", "map_id": "A0A3Q1MI55", "name": "SIPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066483", "map_id": "ENSBTAT00000066483", "name": "SIPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTG9", "map_id": "A0A3Q1MTG9", "name": "RAP1GAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077316", "map_id": "ENSBTAT00000077316", "name": "RAP1GAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LME0", "map_id": "A0A3Q1LME0", "name": "phospho-RAP1GAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075439", "map_id": "ENSBTAT00000075439", "name": "phospho-RAP1GAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047517", "map_id": "none", "name": "RAP1GAP2:14-3-3beta, zeta", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047536", "map_id": "none", "name": "Activation of EPACs by cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047534", "map_id": "none", "name": "Rap1 cAMP-GEFs:cAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10052466", "map_id": "none", "name": "14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047510", "map_id": "A0A3Q1LME0", "name": "RAP1GAP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047515", "map_id": "none", "name": "14-3-3 beta, zeta", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052464", "map_id": "A0A3Q1LME0", "name": "phospho-RAP1GAP2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10052471", "map_id": "none", "name": "PKA/PKG phosphorylate Rap1GAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_427893", "map_id": "P00516", "name": "cGMP-dependent protein kinase 1, alpha isozyme", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000030539", "map_id": "ENSBTAT00000030539", "name": "cGMP-dependent protein kinase 1, alpha isozyme", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071800", "map_id": "none", "name": "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29804", "map_id": "CHEBI:29103", "name": "K+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_74126", "map_id": "CHEBI:29103", "name": "K+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071797", "map_id": "none", "name": "AKAP9:KCNQ1 tetramer:KCNE dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q2KHV0", "map_id": "Q2KHV0", "name": "KCNE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001530", "map_id": "ENSBTAT00000001530", "name": "KCNE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NKS7", "map_id": "Q2NKS7", "name": "KCNE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037245", "map_id": "ENSBTAT00000037245", "name": "KCNE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT75", "map_id": "A0A3Q1MT75", "name": "KCNQ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087044", "map_id": "ENSBTAT00000087044", "name": "KCNQ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPA7", "map_id": "A0A3Q1LPA7", "name": "AKAP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069177", "map_id": "ENSBTAT00000069177", "name": "AKAP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059961", "map_id": "none", "name": "Neu5Ac is cleaved from GM3 by NEU2 to form a globoside (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1605590", "map_id": "CHEBI:15681", "name": "GM3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1605647", "map_id": "CHEBI:17950", "name": "LacCer", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071483", "map_id": "none", "name": "GLTPD1 transports C1P from plasma membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1638840", "map_id": "CHEBI:16197", "name": "C1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5339515", "map_id": "CHEBI:16197", "name": "C1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10071480", "map_id": "Q0VCQ0", "name": "CPTP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010025", "map_id": "ENSBTAT00000010025", "name": "CPTP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084410", "map_id": "none", "name": "B4GALNT1 dimer transfers GalNAc from UDP-GalNAc to GM3 and GD3 gangliosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_8856243", "map_id": "none", "name": "GD3,GM3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_1605641", "map_id": "CHEBI:15681", "name": "GM3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "CHEBI:28424", "map_id": "CHEBI:28424", "name": "CHEBI:28424", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8856242", "map_id": "none", "name": "GD2,GM2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_1605610", "map_id": "CHEBI:51013", "name": "GM2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:28648", "map_id": "CHEBI:28648", "name": "CHEBI:28648", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084407", "map_id": "none", "name": "B4GALNT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q58DI2", "map_id": "Q58DI2", "name": "B4GALNT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005893", "map_id": "ENSBTAT00000005893", "name": "B4GALNT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060316", "map_id": "none", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429776", "map_id": "CHEBI:17636", "name": "SPHM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_429807", "map_id": "CHEBI:17761", "name": "CERA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1610735", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10060313", "map_id": "F1N1R7", "name": "ENPP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000002552", "map_id": "ENSBTAT00000002552", "name": "ENPP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059984", "map_id": "none", "name": "Neu5Ac is cleaved from GM3 by NEU3 to form globoside (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1605649", "map_id": "CHEBI:15681", "name": "GM3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1605618", "map_id": "CHEBI:17950", "name": "LacCer", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10059954", "map_id": "none", "name": "Ganglioside GM2 activator presents GM2 to hexosaminidase for cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10059927", "map_id": "E1BI28", "name": "GM2A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000029099", "map_id": "ENSBTAT00000029099", "name": "GM2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10059929", "map_id": "none", "name": "GM2A:GM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "E1BI28", "map_id": "E1BI28", "name": "GM2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060021", "map_id": "none", "name": "Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1606609", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1861754", "map_id": "CHEBI:33575", "name": "RCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060018", "map_id": "none", "name": "ASAH2-like proteins", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10060309", "map_id": "none", "name": "CERK phosphorylates CERA to form C1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060306", "map_id": "G3MXL8", "name": "CERK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064397", "map_id": "ENSBTAT00000064397", "name": "CERK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059991", "map_id": "none", "name": "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1605713", "map_id": "CHEBI:17636", "name": "SPHM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605750", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605673", "map_id": "CHEBI:52639", "name": "CERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10059988", "map_id": "Q0VD19", "name": "SMPD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000020758", "map_id": "ENSBTAT00000020758", "name": "SMPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059977", "map_id": "none", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1605716", "map_id": "CHEBI:18313", "name": "Gb3Cer", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605637", "map_id": "CHEBI:28061", "name": "Gal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605601", "map_id": "CHEBI:17950", "name": "LacCer", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10059974", "map_id": "none", "name": "GLA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "E1B725", "map_id": "E1B725", "name": "GLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025636", "map_id": "ENSBTAT00000025636", "name": "GLA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060041", "map_id": "none", "name": "Steryl sulfatase hydrolyses sulfate from steroid sulfates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1609648", "map_id": "CHEBI:16814", "name": "DHEA-SO4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_1609650", "map_id": "CHEBI:28689", "name": "DHEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_1609649", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060038", "map_id": "none", "name": "active STS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10071497", "map_id": "none", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5340315", "map_id": "CHEBI:24402", "name": "GSL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5340299", "map_id": "CHEBI:24402", "name": "GSL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10071494", "map_id": "Q3MHF5", "name": "GLTP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000003355", "map_id": "ENSBTAT00000003355", "name": "GLTP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059944", "map_id": "none", "name": "Hexosaminidase A cleaves GalNAc from GM2 to form GM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10060012", "map_id": "none", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060009", "map_id": "none", "name": "SMPD2,3:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N588", "map_id": "F1N588", "name": "SMPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010706", "map_id": "ENSBTAT00000010706", "name": "SMPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059951", "map_id": "none", "name": "Both hexosaminidase A and B can cleave GalNAc from globoside", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1605608", "map_id": "CHEBI:61360", "name": "Globoside", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10059948", "map_id": "none", "name": "HEXA,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10060302", "map_id": "none", "name": "Ceramide glucosyltransferase (UGCG) catalyses the transfer of glucose to ceramide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_744227", "map_id": "CHEBI:18066", "name": "UDP-Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_428270", "map_id": "CHEBI:17761", "name": "CERA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1660674", "map_id": "CHEBI:18368", "name": "Glucosylceramide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10060299", "map_id": "Q08DR4", "name": "UGCG", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000043826", "map_id": "ENSBTAT00000043826", "name": "UGCG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059968", "map_id": "none", "name": "Neu5Ac is cleaved from GM3 by NEU1 and 4 to form a globoside (lysosomal lumen)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10059965", "map_id": "E1BMN0", "name": "NEU4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000019755", "map_id": "ENSBTAT00000019755", "name": "NEU4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048986", "map_id": "none", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428203", "map_id": "CHEBI:37550", "name": "S1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428671", "map_id": "CHEBI:17585", "name": "HD2NAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428686", "map_id": "CHEBI:17553", "name": "PETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048983", "map_id": "A0A3Q1LM94", "name": "SGPL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000080801", "map_id": "ENSBTAT00000080801", "name": "SGPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049116", "map_id": "none", "name": "CERT:ceramide [ER] => ceramide [Golgi] + CERT [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10049108", "map_id": "none", "name": "ceramide:CERT:PPM1L:VAPA/B trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A2VDZ9", "map_id": "A2VDZ9", "name": "VAPB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023164", "map_id": "ENSBTAT00000023164", "name": "VAPB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJG0", "map_id": "A0A452DJG0", "name": "PPM1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053250", "map_id": "ENSBTAT00000053250", "name": "PPM1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_428256", "map_id": "CHEBI:17761", "name": "CERA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q9GKI7", "map_id": "Q9GKI7", "name": "phospho-CERT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056797", "map_id": "ENSBTAT00000056797", "name": "phospho-CERT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049110", "map_id": "none", "name": "CERT:PPM1L:VAPA/B trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10049114", "map_id": "E1BPW1", "name": "OSBP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000027095", "map_id": "ENSBTAT00000027095", "name": "OSBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048860", "map_id": "none", "name": "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200736", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9695889", "map_id": "CHEBI:15525", "name": "PALM-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_428182", "map_id": "CHEBI:17862", "name": "3-ketosphinganine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10048843", "map_id": "none", "name": "PXLP-K-SPTLC1:PXLP-K379-SPTLC2:SPTSS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q5E978", "map_id": "Q5E978", "name": "SPTSSA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018578", "map_id": "ENSBTAT00000018578", "name": "SPTSSA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0IIK4", "map_id": "Q0IIK4", "name": "SPTSSB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085219", "map_id": "ENSBTAT00000085219", "name": "SPTSSB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHG1", "map_id": "Q3MHG1", "name": "SPTLC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002872", "map_id": "ENSBTAT00000002872", "name": "SPTLC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKM3", "map_id": "A5PKM3", "name": "SPTLC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027289", "map_id": "ENSBTAT00000027289", "name": "SPTLC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048858", "map_id": "none", "name": "ORMDL1,2,3", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q0VD15", "map_id": "Q0VD15", "name": "ORMDL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018402", "map_id": "ENSBTAT00000018402", "name": "ORMDL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RQ9", "map_id": "Q29RQ9", "name": "ORMDL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016673", "map_id": "ENSBTAT00000016673", "name": "ORMDL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E972", "map_id": "Q5E972", "name": "ORMDL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027540", "map_id": "ENSBTAT00000027540", "name": "ORMDL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048988", "map_id": "none", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428275", "map_id": "CHEBI:16893", "name": "SPAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428663", "map_id": "CHEBI:17600", "name": "HXAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10049182", "map_id": "none", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429802", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10049179", "map_id": "E1BNX6", "name": "SGMS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000072919", "map_id": "ENSBTAT00000072919", "name": "SGMS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048978", "map_id": "none", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428694", "map_id": "CHEBI:16566", "name": "SPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048975", "map_id": "none", "name": "SGPP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0JNA1", "map_id": "A0JNA1", "name": "SGPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005808", "map_id": "ENSBTAT00000005808", "name": "SGPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0W7", "map_id": "A0A3Q1N0W7", "name": "SGPP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067390", "map_id": "ENSBTAT00000067390", "name": "SGPP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048917", "map_id": "none", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025544", "map_id": "CHEBI:31998", "name": "N-acylphytosphingosine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_428237", "map_id": "CHEBI:46961", "name": "phytosphingosine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_3632878", "map_id": "CHEBI:9254", "name": "STEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048914", "map_id": "A7MBH7", "name": "ACER3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000052101", "map_id": "ENSBTAT00000052101", "name": "ACER3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049161", "map_id": "none", "name": "multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049158", "map_id": "none", "name": "multiphospho-CERT:PPM1L:VAPA/B trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10049163", "map_id": "none", "name": "multiphospho-CERT + PPM1L:VAPA/B => multiphospho-CERT:PPM1L:VAPA/B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049100", "map_id": "none", "name": "PPM1L:VAPA/B dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10049147", "map_id": "Q9GKI7", "name": "phospho-CERT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10082058", "map_id": "none", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13977", "compartment_display": "lipid droplet" }, { "id": "species_6808468", "map_id": "CHEBI:17600", "name": "HXAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_2453691", "map_id": "CHEBI:15756", "name": "PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_10082055", "map_id": "none", "name": "Homologues of ALDH3B2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "A0A3Q1M3Q4", "map_id": "A0A3Q1M3Q4", "name": "LOC508879", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085198", "map_id": "ENSBTAT00000085198", "name": "LOC508879", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JPA0", "map_id": "Q1JPA0", "name": "ALDH3B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076578", "map_id": "ENSBTAT00000076578", "name": "ALDH3B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048910", "map_id": "none", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428126", "map_id": "CHEBI:31488", "name": "DHCE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10048907", "map_id": "Q0II71", "name": "DEGS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000012243", "map_id": "ENSBTAT00000012243", "name": "DEGS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048896", "map_id": "none", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428163", "map_id": "CHEBI:16566", "name": "SPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10048893", "map_id": "A0A3Q1MBG6", "name": "SPHK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000074462", "map_id": "ENSBTAT00000074462", "name": "SPHK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049154", "map_id": "none", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049124", "map_id": "Q9GKI7", "name": "phospho-CERT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049151", "map_id": "A7MB90", "name": "CSNK1G2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022345", "map_id": "ENSBTAT00000022345", "name": "CSNK1G2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048903", "map_id": "none", "name": "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428193", "map_id": "CHEBI:16393", "name": "SPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_428198", "map_id": "CHEBI:9254", "name": "STEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17941", "compartment_display": "early endosome", "complex": "false" }, { "id": "species_10048900", "map_id": "F1MGH9", "name": "ACER1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000010648", "map_id": "ENSBTAT00000010648", "name": "ACER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048889", "map_id": "none", "name": "ceramide + H2O => stearate + sphingosine [Golgi]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_428248", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10048886", "map_id": "E1B8N2", "name": "ACER2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000014354", "map_id": "ENSBTAT00000014354", "name": "ACER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048882", "map_id": "none", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048879", "map_id": "none", "name": "LASS proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MVP2", "map_id": "A0A3Q1MVP2", "name": "CERS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082150", "map_id": "ENSBTAT00000082150", "name": "CERS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJ30", "map_id": "A0A3Q1MJ30", "name": "CERS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080491", "map_id": "ENSBTAT00000080491", "name": "CERS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FUG2", "map_id": "A4FUG2", "name": "CERS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036524", "map_id": "ENSBTAT00000036524", "name": "CERS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7K4", "map_id": "A5D7K4", "name": "CERS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052579", "map_id": "ENSBTAT00000052579", "name": "CERS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049141", "map_id": "none", "name": "PRKD1,2,3 phosphorylates COL4A3BP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049119", "map_id": "Q9GKI7", "name": "CERT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049138", "map_id": "none", "name": "PRKD1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N9F5", "map_id": "A0A3Q1N9F5", "name": "PRKD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081006", "map_id": "ENSBTAT00000081006", "name": "PRKD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIA2", "map_id": "F1MIA2", "name": "PRKD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020721", "map_id": "ENSBTAT00000020721", "name": "PRKD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7L9", "map_id": "E1B7L9", "name": "PRKD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070039", "map_id": "ENSBTAT00000070039", "name": "PRKD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049143", "map_id": "none", "name": "CERT [ER] + ceramide [ER] => CERT:ceramide [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10076151", "map_id": "none", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10076148", "map_id": "none", "name": "ALDH3A2-1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10049004", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428682", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049001", "map_id": "none", "name": "PPAP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MIK4", "map_id": "A0A3Q1MIK4", "name": "PLPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069794", "map_id": "ENSBTAT00000069794", "name": "PLPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZE3", "map_id": "Q3SZE3", "name": "PLPP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015460", "map_id": "ENSBTAT00000015460", "name": "PLPP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049007", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10049121", "map_id": "none", "name": "CERT:PPM1L:VAPA/B [ER] => CERT [cytosol] + PPM1L:VAPA/B [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10076833", "map_id": "none", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10076830", "map_id": "Q1JPA0", "name": "ALDH3B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10091936", "map_id": "none", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091933", "map_id": "F1MXM0", "name": "SPNS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000009765", "map_id": "ENSBTAT00000009765", "name": "SPNS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048995", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_428662", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048992", "map_id": "A0A3Q1MIK4", "name": "PLPP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10076389", "map_id": "none", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5693768", "map_id": "CHEBI:85781", "name": "2HCERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10076386", "map_id": "E1BGC2", "name": "FA2H", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000016212", "map_id": "ENSBTAT00000016212", "name": "FA2H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049189", "map_id": "none", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_429773", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_429789", "map_id": "CHEBI:17636", "name": "SPHM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10049186", "map_id": "F1MF31", "name": "SGMS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000082007", "map_id": "ENSBTAT00000082007", "name": "SGMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091941", "map_id": "none", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091939", "map_id": "none", "name": "SPHK2:SPHK2 inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MBG6", "map_id": "A0A3Q1MBG6", "name": "SPHK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043933", "map_id": "none", "name": "Tyrosine is hydroxylated to dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29506", "map_id": "CHEBI:58315", "name": "L-Tyr", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_209849", "map_id": "CHEBI:15765", "name": "L-Dopa", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71112", "map_id": "CHEBI:15374", "name": "4aOH-BH4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043930", "map_id": "none", "name": "TH:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MAN0", "map_id": "A0A3Q1MAN0", "name": "TH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077835", "map_id": "ENSBTAT00000077835", "name": "TH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073477", "map_id": "none", "name": "Dopachrome is transformed to DHICA by DCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5668572", "compartment_display": "melanosome lumen" }, { "id": "species_5662665", "map_id": "CHEBI:49108", "name": "Dopachrome", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5668572", "compartment_display": "melanosome lumen", "complex": "false" }, { "id": "species_5662670", "map_id": "CHEBI:2003", "name": "DHICA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5668572", "compartment_display": "melanosome lumen", "complex": "false" }, { "id": "species_10073474", "map_id": "none", "name": "DCT:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5668575", "compartment_display": "melanosome membrane", "complex": "true" }, { "id": "F1MC37", "map_id": "F1MC37", "name": "DCT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034881", "map_id": "ENSBTAT00000034881", "name": "DCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044216", "map_id": "none", "name": "CYP4B1 12-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_215075", "map_id": "CHEBI:19138", "name": "12-HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044213", "map_id": "none", "name": "Cytochrome P450 (CYP4B1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q148E6", "map_id": "Q148E6", "name": "CYP4B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015892", "map_id": "ENSBTAT00000015892", "name": "CYP4B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044195", "map_id": "none", "name": "CYP4F12 18-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_352318", "map_id": "CHEBI:63590", "name": "18OH-ARA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044192", "map_id": "none", "name": "Cytochrome P450 (CYP4F12 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10044260", "map_id": "none", "name": "CYP2J2 oxidises ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_215062", "map_id": "none", "name": "cis-EET", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10044257", "map_id": "none", "name": "Cytochrome P450 (CYP2J2 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10035958", "map_id": "none", "name": "CYP4A11 12-hydroxylates DDCX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_42373", "map_id": "CHEBI:39567", "name": "12OH-DDCX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10035955", "map_id": "none", "name": "Cytochrome P450 (CYP4A11 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10048504", "map_id": "none", "name": "SLC8A1,2,3 exchange 3Na+ for Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048501", "map_id": "none", "name": "SLC8A1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B7D0", "map_id": "E1B7D0", "name": "SLC8A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014410", "map_id": "ENSBTAT00000014410", "name": "SLC8A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LST7", "map_id": "A0A3Q1LST7", "name": "SLC8A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077819", "map_id": "ENSBTAT00000077819", "name": "SLC8A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072522", "map_id": "none", "name": "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_5626313", "map_id": "CHEBI:29103", "name": "K+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_167012", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_425958", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10072519", "map_id": "F1MIZ1", "name": "SLC24A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "ENSBTAT00000006382", "map_id": "ENSBTAT00000006382", "name": "SLC24A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048526", "map_id": "none", "name": "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048523", "map_id": "none", "name": "SLC24A1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MD60", "map_id": "F1MD60", "name": "SLC24A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008703", "map_id": "ENSBTAT00000008703", "name": "SLC24A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M073", "map_id": "A0A3Q1M073", "name": "SLC24A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074844", "map_id": "ENSBTAT00000074844", "name": "SLC24A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BM98", "map_id": "E1BM98", "name": "SLC24A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061324", "map_id": "ENSBTAT00000061324", "name": "SLC24A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGG7", "map_id": "E1BGG7", "name": "SLC24A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015768", "map_id": "ENSBTAT00000015768", "name": "SLC24A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048533", "map_id": "none", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_425815", "map_id": "CHEBI:49713", "name": "Li+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_425810", "map_id": "CHEBI:49713", "name": "Li+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10048530", "map_id": "A0A3Q1LSB1", "name": "SLC8B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000070502", "map_id": "ENSBTAT00000070502", "name": "SLC8B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038895", "map_id": "none", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_73663", "map_id": "CHEBI:46245", "name": "CoQ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_76633", "map_id": "CHEBI:17976", "name": "QH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10038882", "map_id": "none", "name": "Complex I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P23934", "map_id": "P23934", "name": "NDUFS6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013078", "map_id": "ENSBTAT00000013078", "name": "NDUFS6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04394", "map_id": "P04394", "name": "NDUFV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006405", "map_id": "ENSBTAT00000006405", "name": "NDUFV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7B1", "map_id": "A0A3Q1M7B1", "name": "NDUFV3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065530", "map_id": "ENSBTAT00000065530", "name": "NDUFV3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0E1", "map_id": "A0A3Q1N0E1", "name": "NDUFV3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15690", "map_id": "P15690", "name": "NDUFS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029301", "map_id": "ENSBTAT00000029301", "name": "NDUFS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIK0", "map_id": "A0A452DIK0", "name": "NDUFA12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019529", "map_id": "ENSBTAT00000019529", "name": "NDUFA12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MG52", "map_id": "A0A3Q1MG52", "name": "NDUFV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075840", "map_id": "ENSBTAT00000075840", "name": "NDUFV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02379", "map_id": "Q02379", "name": "NDUFS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077219", "map_id": "ENSBTAT00000077219", "name": "NDUFS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q85BD6", "map_id": "Q85BD6", "name": "ND5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060577", "map_id": "ENSBTAT00000060577", "name": "ND5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6QTH1", "map_id": "Q6QTH1", "name": "ND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060571", "map_id": "ENSBTAT00000060571", "name": "ND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42026", "map_id": "P42026", "name": "NDUFS7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053067", "map_id": "ENSBTAT00000053067", "name": "NDUFS7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P34943", "map_id": "P34943", "name": "NDUFA9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007189", "map_id": "ENSBTAT00000007189", "name": "NDUFA9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02374", "map_id": "Q02374", "name": "NDUFB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029003", "map_id": "ENSBTAT00000029003", "name": "NDUFB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LFL6", "map_id": "A0A3Q1LFL6", "name": "NDUFC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035646", "map_id": "ENSBTAT00000035646", "name": "NDUFC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFA0", "map_id": "A0A3Q1MFA0", "name": "NDUFB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071194", "map_id": "ENSBTAT00000071194", "name": "NDUFB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M144", "map_id": "A0A3Q1M144", "name": "NDUFB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02377", "map_id": "Q02377", "name": "NDUFA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007925", "map_id": "ENSBTAT00000007925", "name": "NDUFA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02365", "map_id": "Q02365", "name": "NDUFB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016957", "map_id": "ENSBTAT00000016957", "name": "NDUFB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02827", "map_id": "Q02827", "name": "NDUFC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024209", "map_id": "ENSBTAT00000024209", "name": "NDUFC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23935", "map_id": "P23935", "name": "NDUFA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012287", "map_id": "ENSBTAT00000012287", "name": "NDUFA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LW79", "map_id": "A0A3Q1LW79", "name": "NDUFA10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067852", "map_id": "ENSBTAT00000067852", "name": "NDUFA10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P42029", "map_id": "P42029", "name": "NDUFA8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005628", "map_id": "ENSBTAT00000005628", "name": "NDUFA8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02369", "map_id": "Q02369", "name": "NDUFB9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027191", "map_id": "ENSBTAT00000027191", "name": "NDUFB9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02373", "map_id": "Q02373", "name": "NDUFB10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012542", "map_id": "ENSBTAT00000012542", "name": "NDUFB10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIB4", "map_id": "A0A452DIB4", "name": "NDUFA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012512", "map_id": "ENSBTAT00000012512", "name": "NDUFA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02368", "map_id": "Q02368", "name": "NDUFB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016768", "map_id": "ENSBTAT00000016768", "name": "NDUFB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8HXG5", "map_id": "Q8HXG5", "name": "NDUFB11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070642", "map_id": "ENSBTAT00000070642", "name": "NDUFB11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05752", "map_id": "Q05752", "name": "NDUFA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077911", "map_id": "ENSBTAT00000077911", "name": "NDUFA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02370", "map_id": "Q02370", "name": "NDUFA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020018", "map_id": "ENSBTAT00000020018", "name": "NDUFA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LID6", "map_id": "A0A3Q1LID6", "name": "NDUFB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072963", "map_id": "ENSBTAT00000072963", "name": "NDUFB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q95KV7", "map_id": "Q95KV7", "name": "NDUFA13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010276", "map_id": "ENSBTAT00000010276", "name": "NDUFA13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02371", "map_id": "Q02371", "name": "NDUFA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010193", "map_id": "ENSBTAT00000010193", "name": "NDUFA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02380", "map_id": "Q02380", "name": "NDUFB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003197", "map_id": "ENSBTAT00000003197", "name": "NDUFB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8HXG6", "map_id": "Q8HXG6", "name": "NDUFA11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025322", "map_id": "ENSBTAT00000025322", "name": "NDUFA11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBM6", "map_id": "A0A3Q1MBM6", "name": "COA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084872", "map_id": "ENSBTAT00000084872", "name": "COA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6QTH0", "map_id": "Q6QTH0", "name": "ND2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060548", "map_id": "ENSBTAT00000060548", "name": "ND2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03924", "map_id": "P03924", "name": "MT-ND6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060562", "map_id": "ENSBTAT00000060562", "name": "MT-ND6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02367", "map_id": "Q02367", "name": "NDUFB6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007761", "map_id": "ENSBTAT00000007761", "name": "NDUFB6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03898", "map_id": "P03898", "name": "MT-ND3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060547", "map_id": "ENSBTAT00000060547", "name": "MT-ND3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA03", "map_id": "Q5EA03", "name": "TMEM186", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030501", "map_id": "ENSBTAT00000030501", "name": "TMEM186", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03910", "map_id": "P03910", "name": "MT-ND4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060552", "map_id": "ENSBTAT00000060552", "name": "MT-ND4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038893", "map_id": "none", "name": "COQ10A,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "F1MK72", "map_id": "F1MK72", "name": "COQ10B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006115", "map_id": "ENSBTAT00000006115", "name": "COQ10B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMM6", "map_id": "Q1RMM6", "name": "COQ10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005722", "map_id": "ENSBTAT00000005722", "name": "COQ10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080521", "map_id": "none", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10080503", "map_id": "none", "name": "370 kDa subcomplex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "A0A3Q1MP25", "map_id": "A0A3Q1MP25", "name": "ACAD9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085097", "map_id": "ENSBTAT00000085097", "name": "ACAD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX05", "map_id": "Q3SX05", "name": "ECSIT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAZ2", "map_id": "E1BAZ2", "name": "NDUFAF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074751", "map_id": "ENSBTAT00000074751", "name": "NDUFAF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCS4", "map_id": "E1BCS4", "name": "TMEM126B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027441", "map_id": "ENSBTAT00000027441", "name": "TMEM126B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080485", "map_id": "none", "name": "315kDa subcomplex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q2HJI2", "map_id": "Q2HJI2", "name": "NDUFAF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025174", "map_id": "ENSBTAT00000025174", "name": "NDUFAF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FUH5", "map_id": "A4FUH5", "name": "NDUFAF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004122", "map_id": "ENSBTAT00000004122", "name": "NDUFAF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YVD7", "map_id": "A7YVD7", "name": "NDUFAF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009959", "map_id": "ENSBTAT00000009959", "name": "NDUFAF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080505", "map_id": "none", "name": "550kDa complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10080515", "map_id": "none", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10038704", "map_id": "Q02379", "name": "NDUFS5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10080511", "map_id": "none", "name": "FP subcomplex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10080507", "map_id": "none", "name": "815kDa complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10080513", "map_id": "none", "name": "980kDa complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10080517", "map_id": "none", "name": "ND4, ND5 bind the 550kDa complex to form the 815kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10038708", "map_id": "P03910", "name": "MT-ND4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10038712", "map_id": "Q85BD6", "name": "ND5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10080519", "map_id": "none", "name": "COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10038740", "map_id": "none", "name": "TMEM186:MT-ND3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10080501", "map_id": "none", "name": "MCIA complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10038720", "map_id": "Q02367", "name": "NDUFB6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10038716", "map_id": "P03924", "name": "MT-ND6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10038730", "map_id": "none", "name": "COA1:MT-ND2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10038647", "map_id": "none", "name": "Electron transfer from reduced cytochrome c to molecular oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10038546", "map_id": "none", "name": "Cytochrome c (reduced)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38573", "map_id": "CHEBI:38573", "name": "CHEBI:38573", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P62894", "map_id": "P62894", "name": "CYCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007918", "map_id": "ENSBTAT00000007918", "name": "CYCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038548", "map_id": "none", "name": "Cytochrome c (oxidised)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38574", "map_id": "CHEBI:38574", "name": "CHEBI:38574", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038606", "map_id": "none", "name": "Cytochrome c oxidase", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "E1BH77", "map_id": "E1BH77", "name": "LOC783202", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006474", "map_id": "ENSBTAT00000006474", "name": "LOC783202", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68530", "map_id": "P68530", "name": "MT-CO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060549", "map_id": "ENSBTAT00000060549", "name": "MT-CO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LKB8", "map_id": "A0A3Q1LKB8", "name": "COX7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080485", "map_id": "ENSBTAT00000080485", "name": "COX7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6QTG5", "map_id": "Q6QTG5", "name": "COX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060566", "map_id": "ENSBTAT00000060566", "name": "COX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBD7", "map_id": "A0A3Q1MBD7", "name": "COX5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076309", "map_id": "ENSBTAT00000076309", "name": "COX5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6QTG9", "map_id": "Q6QTG9", "name": "COX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060569", "map_id": "ENSBTAT00000060569", "name": "COX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MB49", "map_id": "A0A3Q1MB49", "name": "COX6B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067651", "map_id": "ENSBTAT00000067651", "name": "COX6B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28694", "map_id": "CHEBI:28694", "name": "CHEBI:28694", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q01321", "map_id": "Q01321", "name": "NDUFA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014801", "map_id": "ENSBTAT00000014801", "name": "NDUFA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00426", "map_id": "P00426", "name": "COX5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022949", "map_id": "ENSBTAT00000022949", "name": "COX5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00430", "map_id": "P00430", "name": "COX7C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079150", "map_id": "ENSBTAT00000079150", "name": "COX7C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00423", "map_id": "P00423", "name": "COX4I1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053881", "map_id": "ENSBTAT00000053881", "name": "COX4I1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P13182", "map_id": "P13182", "name": "COX6A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071537", "map_id": "ENSBTAT00000071537", "name": "COX6A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T061", "map_id": "Q3T061", "name": "COX7A2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000943", "map_id": "ENSBTAT00000000943", "name": "COX7A2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038643", "map_id": "none", "name": "COX ancilliary proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A6H784", "map_id": "A6H784", "name": "SCO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016742", "map_id": "ENSBTAT00000016742", "name": "SCO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQS6", "map_id": "A0A3Q1MQS6", "name": "SURF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067855", "map_id": "ENSBTAT00000067855", "name": "SURF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJK7", "map_id": "E1BJK7", "name": "TACO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013031", "map_id": "ENSBTAT00000013031", "name": "TACO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPX9", "map_id": "E1BPX9", "name": "LRPPRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021773", "map_id": "ENSBTAT00000021773", "name": "LRPPRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038611", "map_id": "A8E4L1", "name": "COX19", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "ENSBTAT00000020289", "map_id": "ENSBTAT00000020289", "name": "COX19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038625", "map_id": "none", "name": "COX11,14,16,18,20", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "A0A3Q1MMW4", "map_id": "A0A3Q1MMW4", "name": "COX20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082257", "map_id": "ENSBTAT00000082257", "name": "COX20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5P2", "map_id": "F1N5P2", "name": "COX18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007094", "map_id": "ENSBTAT00000007094", "name": "COX18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMH3", "map_id": "Q1RMH3", "name": "COX14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001069", "map_id": "ENSBTAT00000001069", "name": "COX14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038645", "map_id": "none", "name": "Cytochrome c oxidase:CO", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_9709335", "map_id": "CHEBI:17245", "name": "CO", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10084313", "map_id": "none", "name": "SHC1 in the RET complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084133", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:SHC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074027", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084185", "map_id": "none", "name": "GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084177", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10084183", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084153", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074025", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10084151", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:PLCG1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085755", "map_id": "none", "name": "RET binds GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074005", "map_id": "none", "name": "GFRA1, GFRA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10084137", "map_id": "F1MS00", "name": "RET", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084157", "map_id": "none", "name": "RET:GFRA1,GFRA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084187", "map_id": "none", "name": "GDNF,NRTN bind RET:GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10073999", "map_id": "none", "name": "GDNF,NRTN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10084159", "map_id": "none", "name": "RET:GFRA1,GFRA2:GDNF,NRTN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084379", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084375", "map_id": "none", "name": "SRC-1, RAP1GAP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10084377", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085757", "map_id": "none", "name": "RET binds GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074017", "map_id": "G3MZM3", "name": "GFRA4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084161", "map_id": "none", "name": "RET:GFRA4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084190", "map_id": "none", "name": "RET tyrosine phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084167", "map_id": "none", "name": "2x RET:GFRA:GDNF complexes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084309", "map_id": "none", "name": "p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084175", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084149", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084145", "map_id": "A0A3Q1LNN8", "name": "GRB10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081071", "map_id": "ENSBTAT00000081071", "name": "GRB10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084147", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LNN8", "map_id": "A0A3Q1LNN8", "name": "GRB10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084311", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074031", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084169", "map_id": "none", "name": "RET dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084165", "map_id": "none", "name": "RET:GFRA:GDNF complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084393", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084389", "map_id": "none", "name": "RET interactors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SX40", "map_id": "Q3SX40", "name": "PDLIM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009662", "map_id": "ENSBTAT00000009662", "name": "PDLIM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084391", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:RET interactors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084330", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10084328", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:FRS2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084141", "map_id": "none", "name": "RET binds GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073976", "map_id": "A0A3Q1N8H3", "name": "GFRA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084139", "map_id": "none", "name": "RET:GFRA1,GFRA3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084352", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084348", "map_id": "none", "name": "DOK1,DOK2,DOK4,DOK5,DOK6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N3X9", "map_id": "G3N3X9", "name": "DOK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064953", "map_id": "ENSBTAT00000064953", "name": "DOK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBB8", "map_id": "A7MBB8", "name": "DOK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004337", "map_id": "ENSBTAT00000004337", "name": "DOK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFJ7", "map_id": "A4IFJ7", "name": "DOK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071968", "map_id": "ENSBTAT00000071968", "name": "DOK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCR5", "map_id": "Q0VCR5", "name": "DOK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064819", "map_id": "ENSBTAT00000064819", "name": "DOK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084350", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084131", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074029", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084194", "map_id": "none", "name": "p-5Y-RET complexes bind GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084192", "map_id": "none", "name": "p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084196", "map_id": "none", "name": "ARTN binds RET:GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10073972", "map_id": "E1BD76", "name": "ARTN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10084155", "map_id": "none", "name": "RET:GFRA1,GFRA3:ARTN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084135", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10084198", "map_id": "none", "name": "PSPN binds RET:GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10074013", "map_id": "E1BCL0", "name": "PSPN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10084163", "map_id": "none", "name": "RET:GFRA4:PSPN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084326", "map_id": "none", "name": "p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084324", "map_id": "none", "name": "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10061049", "map_id": "none", "name": "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023891", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023901", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10061028", "map_id": "F1N1W2", "name": "IPMK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000014872", "map_id": "ENSBTAT00000014872", "name": "IPMK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061017", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023922", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10060948", "map_id": "none", "name": "IP6K1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0II95", "map_id": "Q0II95", "name": "IP6K1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015405", "map_id": "ENSBTAT00000015405", "name": "IP6K1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6Q4Q6", "map_id": "F6Q4Q6", "name": "IP6K2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030644", "map_id": "ENSBTAT00000030644", "name": "IP6K2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061128", "map_id": "none", "name": "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023892", "map_id": "CHEBI:16155", "name": "I(1,3,4,6)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10061131", "map_id": "none", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023948", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10061052", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023929", "map_id": "CHEBI:17401", "name": "IP6", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023940", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10061119", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023941", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10061137", "map_id": "none", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023907", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10060993", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10060990", "map_id": "E1BGX9", "name": "IPPK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000015737", "map_id": "ENSBTAT00000015737", "name": "IPPK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061031", "map_id": "none", "name": "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023935", "map_id": "CHEBI:16067", "name": "I(1,4,5,6)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10060951", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023932", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023931", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10067955", "map_id": "none", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067950", "map_id": "none", "name": "HSP40:HSP70:ATP:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N6Q0", "map_id": "F1N6Q0", "name": "DNAJA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021199", "map_id": "ENSBTAT00000021199", "name": "DNAJA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E954", "map_id": "Q5E954", "name": "DNAJA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021637", "map_id": "ENSBTAT00000021637", "name": "DNAJA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJ94", "map_id": "Q2HJ94", "name": "DNAJA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004890", "map_id": "ENSBTAT00000004890", "name": "DNAJA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q27975", "map_id": "Q27975", "name": "HSPA1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017500", "map_id": "ENSBTAT00000017500", "name": "HSPA1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067952", "map_id": "none", "name": "HSP40:HSP70:ADP:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10067948", "map_id": "none", "name": "HSP40s", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068022", "map_id": "none", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068020", "map_id": "none", "name": "HSP70:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068018", "map_id": "none", "name": "HSP40:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065708", "map_id": "none", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065697", "map_id": "F1MW01", "name": "ESPL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000011761", "map_id": "ENSBTAT00000011761", "name": "ESPL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065705", "map_id": "none", "name": "ESPL1 Autocleaved", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MW01", "map_id": "F1MW01", "name": "ESPL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065726", "map_id": "none", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065722", "map_id": "none", "name": "Homologues of PTTG1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3N089", "map_id": "G3N089", "name": "PTTG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066220", "map_id": "ENSBTAT00000066220", "name": "PTTG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIH5", "map_id": "A0A452DIH5", "name": "PTTG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MYU8", "map_id": "G3MYU8", "name": "PTTG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065724", "map_id": "none", "name": "PTTG1:ESPL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091145", "map_id": "none", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9624879", "map_id": "none", "name": "Nuclear envelope vesicle", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10091134", "map_id": "none", "name": "RAN:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3MZP2", "map_id": "G3MZP2", "name": "RAN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033457", "map_id": "ENSBTAT00000033457", "name": "RAN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E619", "map_id": "G5E619", "name": "RAN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091143", "map_id": "none", "name": "RAN:GTP:Nuclear envelope vesicles", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10091141", "map_id": "none", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_10043519", "map_id": "none", "name": "RAN:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091138", "map_id": "A0A3Q1LX10", "name": "RCC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "false" }, { "id": "ENSBTAT00000066656", "map_id": "ENSBTAT00000066656", "name": "RCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091132", "map_id": "none", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10044128", "map_id": "E1BFV0", "name": "KPNB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008650", "map_id": "ENSBTAT00000008650", "name": "KPNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091128", "map_id": "A6QQV8", "name": "phospho-LBR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "ENSBTAT00000011125", "map_id": "ENSBTAT00000011125", "name": "LBR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091130", "map_id": "none", "name": "p-S71,S86-LBR:KPNB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "A6QQV8", "map_id": "A6QQV8", "name": "LBR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFV0", "map_id": "E1BFV0", "name": "KPNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091656", "map_id": "none", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091652", "map_id": "G3X8E2", "name": "VPS4A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000065503", "map_id": "ENSBTAT00000065503", "name": "VPS4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091648", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "F1N7R5", "map_id": "F1N7R5", "name": "CC2D1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021129", "map_id": "ENSBTAT00000021129", "name": "CC2D1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B828", "map_id": "E1B828", "name": "LEMD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020642", "map_id": "ENSBTAT00000020642", "name": "LEMD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091654", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "G3X8E2", "map_id": "G3X8E2", "name": "VPS4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091658", "map_id": "none", "name": "CHMP7 binds CC2D1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10091644", "map_id": "none", "name": "LEMD2:ESCRT-III:IST1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "species_10091640", "map_id": "F1N7R5", "name": "CC2D1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10091646", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10091661", "map_id": "none", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040834", "map_id": "none", "name": "alpha-beta tubulin dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091634", "map_id": "none", "name": "CHMP7 binds LEMD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052771", "map_id": "A6H704", "name": "CHMP7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10070769", "map_id": "E1B828", "name": "LEMD2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10091632", "map_id": "none", "name": "LEMD2:CHMP7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10091663", "map_id": "none", "name": "Formation of the CTF18 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10039904", "map_id": "F1MTU0", "name": "DSCC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000020389", "map_id": "ENSBTAT00000020389", "name": "DSCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039900", "map_id": "P0CG11", "name": "CHTF8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000002226", "map_id": "ENSBTAT00000002226", "name": "CHTF8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039896", "map_id": "E1B8Q4", "name": "CHTF18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000026311", "map_id": "ENSBTAT00000026311", "name": "CHTF18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039906", "map_id": "none", "name": "CTF18 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B8Q4", "map_id": "E1B8Q4", "name": "CHTF18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CG11", "map_id": "P0CG11", "name": "CHTF8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTU0", "map_id": "F1MTU0", "name": "DSCC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057418", "map_id": "none", "name": "KCNJs transport K+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057415", "map_id": "none", "name": "KCNJ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O19182", "map_id": "O19182", "name": "KCNJ2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010914", "map_id": "ENSBTAT00000010914", "name": "KCNJ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4V6", "map_id": "A0A3Q1M4V6", "name": "KCNJ4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078632", "map_id": "ENSBTAT00000078632", "name": "KCNJ4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCI4", "map_id": "E1BCI4", "name": "KCNJ14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000089", "map_id": "ENSBTAT00000000089", "name": "KCNJ14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064591", "map_id": "none", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_2162214", "map_id": "CHEBI:61011", "name": "all-E-10PrP2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162213", "map_id": "CHEBI:30763", "name": "PHB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162207", "map_id": "CHEBI:64136", "name": "DHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10064588", "map_id": "F1N1G6", "name": "COQ2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000007549", "map_id": "ENSBTAT00000007549", "name": "COQ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046968", "map_id": "none", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_389545", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10046965", "map_id": "none", "name": "IDH1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A140T8A5", "map_id": "A0A140T8A5", "name": "IDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027348", "map_id": "ENSBTAT00000027348", "name": "IDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058524", "map_id": "none", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1474124", "map_id": "CHEBI:18372", "name": "DHNTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1475054", "map_id": "CHEBI:15266", "name": "PPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1474179", "map_id": "CHEBI:17804", "name": "PTHP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10058521", "map_id": "none", "name": "p-PTPS hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MA59", "map_id": "A0A3Q1MA59", "name": "PTS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030411", "map_id": "ENSBTAT00000030411", "name": "PTS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058511", "map_id": "none", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058500", "map_id": "none", "name": "GCH1 decamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZ14", "map_id": "F1MZ14", "name": "GCH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009020", "map_id": "ENSBTAT00000009020", "name": "GCH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29502", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10058509", "map_id": "none", "name": "2GCHFR:GCH1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q32L41", "map_id": "Q32L41", "name": "GCHFR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017922", "map_id": "ENSBTAT00000017922", "name": "GCHFR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058785", "map_id": "none", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058778", "map_id": "none", "name": "PTPS hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10058782", "map_id": "F1MDQ6", "name": "PRKG2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000003877", "map_id": "ENSBTAT00000003877", "name": "PRKG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058514", "map_id": "none", "name": "GCHFR binds to GCH1 and negatively regulates its activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058507", "map_id": "none", "name": "GCHFR pentamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10085853", "map_id": "none", "name": "TTPA transports alpha-TOH from lysosomal membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085849", "map_id": "none", "name": "TTPA:alpha-TOH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_8874708", "map_id": "CHEBI:18145", "name": "alpha-TOH", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "F1N086", "map_id": "F1N086", "name": "TTPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030426", "map_id": "ENSBTAT00000030426", "name": "TTPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085851", "map_id": "none", "name": "TTPA:alpha-TOH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085855", "map_id": "none", "name": "TTPA binds alpha-TOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085847", "map_id": "F1N086", "name": "TTPA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081928", "map_id": "none", "name": "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_6806366", "map_id": "CHEBI:90152", "name": "MK4 epoxide", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_6806362", "map_id": "CHEBI:78277", "name": "MK4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10081925", "map_id": "G3MZM8", "name": "VKORC1L1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000064807", "map_id": "ENSBTAT00000064807", "name": "VKORC1L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038427", "map_id": "none", "name": "VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10038422", "map_id": "none", "name": "VKORC1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q6B4J2", "map_id": "Q6B4J2", "name": "VKORC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000519", "map_id": "ENSBTAT00000000519", "name": "VKORC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038425", "map_id": "none", "name": "VKORC1 inhibitors:VKORC1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10090493", "map_id": "none", "name": "VKORC1 inhibitors binds VKORC1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_9035082", "map_id": "none", "name": "VKORC1 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081935", "map_id": "none", "name": "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_6806891", "map_id": "CHEBI:28869", "name": "menadione", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_6806657", "map_id": "CHEBI:57533", "name": "GGPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_6806656", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10081932", "map_id": "F1MQC8", "name": "UBIAD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000018617", "map_id": "ENSBTAT00000018617", "name": "UBIAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054393", "map_id": "none", "name": "RDH11 reduces RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054390", "map_id": "none", "name": "RBP2:atRAL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MBG1", "map_id": "A7MBG1", "name": "RBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078995", "map_id": "ENSBTAT00000078995", "name": "RBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054388", "map_id": "none", "name": "RBP2:atROL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_975590", "map_id": "CHEBI:17336", "name": "atROL", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10035574", "map_id": "E1BM93", "name": "RDH11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10066249", "map_id": "none", "name": "atROL binds RBP1 (parenchymal cell)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2473610", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035554", "map_id": "none", "name": "Homologues of RBP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LU75", "map_id": "A0A3Q1LU75", "name": "LOC101906939", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012885", "map_id": "ENSBTAT00000012885", "name": "LOC101906939", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ95", "map_id": "A0A452DJ95", "name": "RBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015936", "map_id": "ENSBTAT00000015936", "name": "RBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065443", "map_id": "none", "name": "RBP1:atROL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10054395", "map_id": "none", "name": "atROL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054386", "map_id": "A7MBG1", "name": "RBP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10070971", "map_id": "none", "name": "APOM binds retinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10070967", "map_id": "A0A3Q1MB70", "name": "APOM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000075540", "map_id": "ENSBTAT00000075540", "name": "APOM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5246487", "map_id": "none", "name": "retinoids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10070969", "map_id": "none", "name": "APOM:retinoids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1MB70", "map_id": "A0A3Q1MB70", "name": "APOM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065437", "map_id": "none", "name": "atRAL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10069948", "map_id": "none", "name": "BCO2:Fe2+ cleaves betaC to APO10al and bION", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5164389", "map_id": "CHEBI:17579", "name": "betaC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5164390", "map_id": "CHEBI:32325", "name": "bION", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5164383", "map_id": "CHEBI:53153", "name": "APO10al", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10069945", "map_id": "none", "name": "BCO2:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F1N2Z9", "map_id": "F1N2Z9", "name": "BCO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048395", "map_id": "ENSBTAT00000048395", "name": "BCO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054382", "map_id": "none", "name": "PLB1 hydrolyses RPALM to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_975591", "map_id": "CHEBI:17616", "name": "RPALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10054379", "map_id": "A0A3Q1LP79", "name": "PLB1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000076923", "map_id": "ENSBTAT00000076923", "name": "PLB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065441", "map_id": "none", "name": "atROL binds RBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2473616", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065439", "map_id": "none", "name": "RBP1:atROL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065445", "map_id": "none", "name": "Parenchymal atROL translocates to HSCs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10054404", "map_id": "none", "name": "BCMO1:Fe2+ cleaves betaC to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975643", "map_id": "CHEBI:17579", "name": "betaC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10054401", "map_id": "none", "name": "BCMO1:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N3B7", "map_id": "F1N3B7", "name": "BCO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048748", "map_id": "ENSBTAT00000048748", "name": "BCO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054375", "map_id": "none", "name": "PNLIP:CLPS hydrolyses RPALM to atROL and PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10041236", "map_id": "none", "name": "PNLIP:CLPS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0JNQ7", "map_id": "A0JNQ7", "name": "CLPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022391", "map_id": "ENSBTAT00000022391", "name": "CLPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJQ9", "map_id": "E1BJQ9", "name": "PNLIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001012", "map_id": "ENSBTAT00000001012", "name": "PNLIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066247", "map_id": "none", "name": "AKRs reduce RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066244", "map_id": "none", "name": "AKRs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N678", "map_id": "F1N678", "name": "AKR1B10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042657", "map_id": "none", "name": "SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_199238", "map_id": "CHEBI:15956", "name": "Btn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_199207", "map_id": "CHEBI:15956", "name": "Btn", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10042645", "map_id": "none", "name": "SLC5A6:PDZD11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q32LE7", "map_id": "Q32LE7", "name": "PDZD11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017091", "map_id": "ENSBTAT00000017091", "name": "PDZD11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN65", "map_id": "F1MN65", "name": "SLC5A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032961", "map_id": "ENSBTAT00000032961", "name": "SLC5A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066401", "map_id": "none", "name": "HLCS biotinylates 6x(PCCA:PCCB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066388", "map_id": "none", "name": "6x(PCCA:PCCB)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10066394", "map_id": "none", "name": "6x(Btn-PCCA:PCCB)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10066398", "map_id": "F1MJL3", "name": "HLCS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000057284", "map_id": "ENSBTAT00000057284", "name": "HLCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067733", "map_id": "none", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10042936", "map_id": "none", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_111355", "map_id": "CHEBI:15635", "name": "THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10042933", "map_id": "G3X7X2", "name": "SLC25A32", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000048106", "map_id": "ENSBTAT00000048106", "name": "SLC25A32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081339", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6801458", "map_id": "CHEBI:15638", "name": "5,10-methenyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10081336", "map_id": "none", "name": "MTHFD2, D2L", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A452DI11", "map_id": "A0A452DI11", "name": "MTHFD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006419", "map_id": "ENSBTAT00000006419", "name": "MTHFD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNJ2", "map_id": "E1BNJ2", "name": "MTHFD2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061329", "map_id": "ENSBTAT00000061329", "name": "MTHFD2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042940", "map_id": "none", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_200716", "map_id": "CHEBI:27470", "name": "FOLA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_197965", "map_id": "CHEBI:27470", "name": "FOLA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10042919", "map_id": "Q05B81", "name": "SLC46A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000035283", "map_id": "ENSBTAT00000035283", "name": "SLC46A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082078", "map_id": "none", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111353", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197969", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10082075", "map_id": "none", "name": "ALDH1L1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BMG9", "map_id": "E1BMG9", "name": "phospho-ALDH1L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043693", "map_id": "ENSBTAT00000043693", "name": "phospho-ALDH1L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042929", "map_id": "none", "name": "SLC19A1 transports 5-methyl-THF from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_200709", "map_id": "CHEBI:15641", "name": "5-methyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_200665", "map_id": "CHEBI:15641", "name": "5-methyl-THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10042926", "map_id": "A0A3Q1MU29", "name": "SLC19A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000082124", "map_id": "ENSBTAT00000082124", "name": "SLC19A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041840", "map_id": "none", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73604", "map_id": "CHEBI:15633", "name": "DHF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041835", "map_id": "A0A140T872", "name": "DHFR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010103", "map_id": "ENSBTAT00000010103", "name": "DHFR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087442", "map_id": "none", "name": "FOLR2 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10086761", "map_id": "none", "name": "FOLR2:FOLA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0VCN9", "map_id": "Q0VCN9", "name": "FOLR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027602", "map_id": "ENSBTAT00000027602", "name": "FOLR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086759", "map_id": "Q0VCN9", "name": "FOLR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10092306", "map_id": "none", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092303", "map_id": "none", "name": "DHFR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A140T872", "map_id": "A0A140T872", "name": "DHFR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082068", "map_id": "none", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6808499", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_200679", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10082065", "map_id": "none", "name": "ADH1L2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BDG9", "map_id": "E1BDG9", "name": "phospho-ALDH1L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008298", "map_id": "ENSBTAT00000008298", "name": "phospho-ALDH1L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086763", "map_id": "none", "name": "FOLR2 binds FOLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10042922", "map_id": "none", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10041838", "map_id": "none", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10081346", "map_id": "none", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803257", "map_id": "CHEBI:63907", "name": "5-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200640", "map_id": "CHEBI:65049", "name": "5,10-methenyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10081343", "map_id": "Q1RMT3", "name": "MTHFS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026669", "map_id": "ENSBTAT00000026669", "name": "MTHFS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076485", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10076482", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q3SZ20", "map_id": "Q3SZ20", "name": "SHMT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038244", "map_id": "ENSBTAT00000038244", "name": "SHMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081349", "map_id": "none", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5389850", "map_id": "CHEBI:15637", "name": "10-formyl-THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041817", "map_id": "none", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041814", "map_id": "none", "name": "NADK:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NKT9", "map_id": "A0A3Q1NKT9", "name": "NADK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069099", "map_id": "ENSBTAT00000069099", "name": "NADK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042906", "map_id": "none", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8938083", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8938078", "map_id": "CHEBI:33019", "name": "PPi(3-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8938090", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10042903", "map_id": "none", "name": "4xNMNAT3:4xMg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1NCV5", "map_id": "A0A3Q1NCV5", "name": "NMNAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074137", "map_id": "ENSBTAT00000074137", "name": "NMNAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088666", "map_id": "none", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10088663", "map_id": "none", "name": "NADK2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LR42", "map_id": "A0A3Q1LR42", "name": "NADK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077253", "map_id": "ENSBTAT00000077253", "name": "NADK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086748", "map_id": "none", "name": "NT5E:Zn2+ hydrolyses NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_352330", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8940067", "map_id": "CHEBI:14649", "name": "NMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10036204", "map_id": "none", "name": "NT5E:Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MCG3", "map_id": "A0A3Q1MCG3", "name": "NT5E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074100", "map_id": "ENSBTAT00000074100", "name": "NT5E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086750", "map_id": "none", "name": "NT5E:Zn2+ hydrolyses NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8940077", "map_id": "CHEBI:15927", "name": "NRNAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10085374", "map_id": "none", "name": "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870342", "map_id": "CHEBI:57967", "name": "ADP-ribose", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_8870343", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10085371", "map_id": "none", "name": "BST1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MLP3", "map_id": "F1MLP3", "name": "BST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008097", "map_id": "ENSBTAT00000008097", "name": "BST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085362", "map_id": "none", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869377", "map_id": "CHEBI:15927", "name": "NR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8869353", "map_id": "CHEBI:14649", "name": "NMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10085356", "map_id": "Q3ZBX2", "name": "ITGB1BP3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000044763", "map_id": "ENSBTAT00000044763", "name": "ITGB1BP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085365", "map_id": "none", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085349", "map_id": "A0A3Q1M5Y0", "name": "NMRK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072443", "map_id": "ENSBTAT00000072443", "name": "NMRK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081977", "map_id": "none", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807473", "map_id": "CHEBI:64085", "name": "R-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6807477", "map_id": "CHEBI:64084", "name": "S-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10081974", "map_id": "none", "name": "APOA1BP dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MF13", "map_id": "A0A3Q1MF13", "name": "NAXE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080451", "map_id": "ENSBTAT00000080451", "name": "NAXE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071643", "map_id": "none", "name": "NNMT transfers CH3 from SAM to NAM to form MNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039927", "map_id": "E1BEK0", "name": "LOC511161", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000040069", "map_id": "ENSBTAT00000040069", "name": "LOC511161", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086623", "map_id": "none", "name": "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8938276", "map_id": "CHEBI:133202", "name": "(ADP-D-ribosyl)(n)-acceptor", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8938282", "map_id": "CHEBI:133203", "name": "(ADP-D-ribosyl)(n+1)-acceptor", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086620", "map_id": "none", "name": "PARPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6R6Y8", "map_id": "F6R6Y8", "name": "PARP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029045", "map_id": "ENSBTAT00000029045", "name": "PARP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0E5", "map_id": "A0A3Q1M0E5", "name": "PARP16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084343", "map_id": "ENSBTAT00000084343", "name": "PARP16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRP9", "map_id": "F1MRP9", "name": "PARP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012765", "map_id": "ENSBTAT00000012765", "name": "PARP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082143", "map_id": "none", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6809289", "map_id": "CHEBI:74452", "name": "NMNH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10082140", "map_id": "Q29RH3", "name": "NUDT12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000039965", "map_id": "ENSBTAT00000039965", "name": "NUDT12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041824", "map_id": "none", "name": "NAMPT transfers PRIB to NAM to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197220", "map_id": "CHEBI:15763", "name": "NAMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041821", "map_id": "A0A3Q1M241", "name": "NAMPT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083136", "map_id": "ENSBTAT00000083136", "name": "NAMPT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041808", "map_id": "none", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041805", "map_id": "none", "name": "NAPRT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N5S3", "map_id": "A0A3Q1N5S3", "name": "NAPRT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084634", "map_id": "ENSBTAT00000084634", "name": "NAPRT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081984", "map_id": "none", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10081981", "map_id": "E1BNQ4", "name": "NAXD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000015238", "map_id": "ENSBTAT00000015238", "name": "NAXD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088867", "map_id": "none", "name": "RNLS:FAD oxidises dh-beta-NAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8956473", "map_id": "none", "name": "dh-beta-NAD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:90174", "map_id": "CHEBI:90174", "name": "CHEBI:90174", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:90171", "map_id": "CHEBI:90171", "name": "CHEBI:90171", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_351629", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10088864", "map_id": "none", "name": "RNLS:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1NF84", "map_id": "A0A3Q1NF84", "name": "RNLS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069540", "map_id": "ENSBTAT00000069540", "name": "RNLS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049170", "map_id": "none", "name": "SLC5A8 transports monocarboxylates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429739", "map_id": "none", "name": "monocarboxylates transported by SLC5A8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32544", "map_id": "CHEBI:32544", "name": "CHEBI:32544", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429748", "map_id": "none", "name": "monocarboxylates transported by SLC5A8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10049167", "map_id": "C8KIL7", "name": "SLC5A8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000015315", "map_id": "ENSBTAT00000015315", "name": "SLC5A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085352", "map_id": "none", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869365", "map_id": "CHEBI:58527", "name": "NAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10085359", "map_id": "none", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10042915", "map_id": "none", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_200492", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_8878981", "map_id": "CHEBI:33019", "name": "PPi(3-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_200499", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10042912", "map_id": "none", "name": "6xNMNAT1:6xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0VD50", "map_id": "Q0VD50", "name": "NMNAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082151", "map_id": "ENSBTAT00000082151", "name": "NMNAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041831", "map_id": "none", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197238", "map_id": "CHEBI:29959", "name": "QUIN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041828", "map_id": "A0A3Q1M3Z8", "name": "QPRT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083204", "map_id": "ENSBTAT00000083204", "name": "QPRT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086630", "map_id": "none", "name": "CD38 hydrolyses NAD+ to NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10086627", "map_id": "A0A3Q1N5J2", "name": "CD38", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000073897", "map_id": "ENSBTAT00000073897", "name": "CD38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053298", "map_id": "none", "name": "Molybdenum ion transfer onto molybdopterin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_947561", "map_id": "CHEBI:36264", "name": "MoO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_947496", "map_id": "CHEBI:58698", "name": "MPT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_947539", "map_id": "CHEBI:25372", "name": "MoCo", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10053295", "map_id": "none", "name": "3xGPHN:3xMg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1ME13", "map_id": "A0A3Q1ME13", "name": "GPHN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081310", "map_id": "ENSBTAT00000081310", "name": "GPHN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053266", "map_id": "none", "name": "Exchange of oxygen with sulfur in MoCo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_947575", "map_id": "CHEBI:60102", "name": "sulfurated MoCo", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29432", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10053263", "map_id": "Q9N0E7", "name": "MOCOS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000065375", "map_id": "ENSBTAT00000065375", "name": "MOCOS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053287", "map_id": "none", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053272", "map_id": "none", "name": "MOCS3:Zn2+ (red.)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A1A4L8", "map_id": "A1A4L8", "name": "MOCS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070167", "map_id": "ENSBTAT00000070167", "name": "MOCS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10053277", "map_id": "none", "name": "MOCS3-S-S(1-):Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10053284", "map_id": "none", "name": "PXLP-K258-NFS1-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A5PKG4", "map_id": "A5PKG4", "name": "NFS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009149", "map_id": "ENSBTAT00000009149", "name": "NFS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053352", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965131", "map_id": "CHEBI:17310", "name": "PXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29390", "map_id": "CHEBI:18405", "name": "PXLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10053345", "map_id": "none", "name": "2xPDXK:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0II59", "map_id": "Q0II59", "name": "PDXK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024203", "map_id": "ENSBTAT00000024203", "name": "PDXK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066619", "map_id": "none", "name": "AOX1 oxidises PXL to PDXate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3204324", "map_id": "CHEBI:17405", "name": "PDXate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066616", "map_id": "none", "name": "2xAOX1:cofactors", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:33722", "map_id": "CHEBI:33722", "name": "CHEBI:33722", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:44074", "map_id": "CHEBI:44074", "name": "CHEBI:44074", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJG6", "map_id": "A0A3Q1LJG6", "name": "AOX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075745", "map_id": "ENSBTAT00000075745", "name": "AOX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053361", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964952", "map_id": "CHEBI:28803", "name": "PDXP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10053358", "map_id": "none", "name": "2xPNPO:2xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q5E9K3", "map_id": "Q5E9K3", "name": "PNPO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016263", "map_id": "ENSBTAT00000016263", "name": "PNPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053363", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965146", "map_id": "CHEBI:18335", "name": "PXAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10053348", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964945", "map_id": "CHEBI:16410", "name": "PXA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10053350", "map_id": "none", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965053", "map_id": "CHEBI:16709", "name": "PDX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041753", "map_id": "none", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196934", "map_id": "CHEBI:18385", "name": "THMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29480", "map_id": "CHEBI:58937", "name": "ThDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10041750", "map_id": "none", "name": "2xTPK1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LMH4", "map_id": "A0A3Q1LMH4", "name": "TPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085465", "map_id": "ENSBTAT00000085465", "name": "TPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042799", "map_id": "none", "name": "SLC19A2/3 transport extracellular THMN to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_199622", "map_id": "CHEBI:18385", "name": "THMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10042796", "map_id": "none", "name": "SLC19A2/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A7E352", "map_id": "A7E352", "name": "SLC19A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084175", "map_id": "ENSBTAT00000084175", "name": "SLC19A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLU2", "map_id": "E1BLU2", "name": "SLC19A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027006", "map_id": "ENSBTAT00000027006", "name": "SLC19A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066585", "map_id": "none", "name": "MMAB transfers adenosyl group from ATP to cob(I)alamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3159260", "map_id": "CHEBI:15982", "name": "cob(I)alamin", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_3159274", "map_id": "CHEBI:15266", "name": "PPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10066582", "map_id": "none", "name": "3xMMAB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1NBS4", "map_id": "A0A3Q1NBS4", "name": "MMAB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056628", "map_id": "ENSBTAT00000056628", "name": "MMAB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066587", "map_id": "none", "name": "MMAA:MUT binds AdoCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10033882", "map_id": "none", "name": "2xMMAA:2xMUT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10066458", "map_id": "none", "name": "GIF binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066454", "map_id": "E1BCN2", "name": "CBLIF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000015993", "map_id": "ENSBTAT00000015993", "name": "CBLIF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3000125", "map_id": "CHEBI:28911", "name": "Cbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10066456", "map_id": "none", "name": "GIF:Cbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_3000241", "map_id": "CHEBI:28911", "name": "Cbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "E1BCN2", "map_id": "E1BCN2", "name": "CBLIF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066461", "map_id": "none", "name": "CD320 transports extracellular TCII:Cbl to endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066428", "map_id": "none", "name": "TCII:Cbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q9XSC9", "map_id": "Q9XSC9", "name": "TCN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029446", "map_id": "ENSBTAT00000029446", "name": "TCN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066440", "map_id": "A6QNY1", "name": "CD320", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005777", "map_id": "ENSBTAT00000005777", "name": "CD320", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066438", "map_id": "none", "name": "TCII:Cbl:CD320", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "A6QNY1", "map_id": "A6QNY1", "name": "CD320", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076254", "map_id": "none", "name": "CTRC hydrolyses PRSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10076243", "map_id": "A7YWU9", "name": "PRSS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076247", "map_id": "A7YWU9", "name": "PRSS2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076245", "map_id": "A7YWU9", "name": "PRSS2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076251", "map_id": "A0A3Q1MGU3", "name": "CTRC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000071882", "map_id": "ENSBTAT00000071882", "name": "CTRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066526", "map_id": "none", "name": "Pancreatic proteases degrade TCN1:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066519", "map_id": "none", "name": "TCN1:Cbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BCU6", "map_id": "E1BCU6", "name": "TCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027423", "map_id": "ENSBTAT00000027423", "name": "TCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066523", "map_id": "none", "name": "PRSS1,3,CTRB1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10066430", "map_id": "none", "name": "TCII binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066426", "map_id": "Q9XSC9", "name": "TCN2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10066576", "map_id": "none", "name": "MMADHC targets transport of cytosolic cob(II)alamin to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066565", "map_id": "none", "name": "MMACHC:MMADHC:cob(II)alamin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M6Z9", "map_id": "A0A3Q1M6Z9", "name": "MMADHC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087246", "map_id": "ENSBTAT00000087246", "name": "MMADHC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3149479", "map_id": "CHEBI:16304", "name": "cob(II)alamin", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q5E9C8", "map_id": "Q5E9C8", "name": "MMACHC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022638", "map_id": "ENSBTAT00000022638", "name": "MMACHC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066567", "map_id": "none", "name": "MMACHC:MMADHC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_3149564", "map_id": "CHEBI:16304", "name": "cob(II)alamin", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10066450", "map_id": "none", "name": "Endosomal TCII:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "species_10066442", "map_id": "none", "name": "TCII:Cbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17940", "compartment_display": "endosome", "complex": "true" }, { "id": "species_10066448", "map_id": "none", "name": "TCII:Cbl", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10066569", "map_id": "none", "name": "cob(II)alamin dissociates from MMACHC:MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10066473", "map_id": "none", "name": "TCII:Cbl is degraded to release Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_3000239", "map_id": "CHEBI:28911", "name": "Cbl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10066571", "map_id": "none", "name": "MMACHC:cob(II)alamin binds MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066563", "map_id": "A0A3Q1M6Z9", "name": "MMADHC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066499", "map_id": "none", "name": "MMACHC:cob(II)alamin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10066444", "map_id": "none", "name": "CD320:TCII:Cbl dissociates into CD320 and TCII:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "reaction_10066574", "map_id": "none", "name": "MMACHC decyanates CNCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066497", "map_id": "Q5E9C8", "name": "MMACHC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3149505", "map_id": "CHEBI:17439", "name": "CNCbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1130611", "map_id": "CHEBI:18407", "name": "HCN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10066528", "map_id": "none", "name": "TCN1 binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066517", "map_id": "E1BCU6", "name": "TCN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_3132775", "map_id": "none", "name": "Food proteins:Cbl", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_3132772", "map_id": "none", "name": "Food proteins", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10066882", "map_id": "none", "name": "TCN1 binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10066471", "map_id": "none", "name": "Endosomal GIF:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "species_10066469", "map_id": "none", "name": "GIF:Cbl", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17940", "compartment_display": "endosome", "complex": "true" }, { "id": "species_10066465", "map_id": "none", "name": "GIF:Cbl", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10066502", "map_id": "none", "name": "MMACHC reduces Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10042648", "map_id": "none", "name": "SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_199192", "map_id": "CHEBI:7916", "name": "PanK", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_196820", "map_id": "CHEBI:7916", "name": "PanK", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10041737", "map_id": "none", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196786", "map_id": "CHEBI:15905", "name": "PPanK", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196834", "map_id": "CHEBI:15769", "name": "PPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041734", "map_id": "none", "name": "2xPPCS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3S5ZP75", "map_id": "A0A3S5ZP75", "name": "PPCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017259", "map_id": "ENSBTAT00000017259", "name": "PPCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041756", "map_id": "none", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196778", "map_id": "CHEBI:15468", "name": "DP-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041741", "map_id": "A0A3Q1MSN7", "name": "COASY", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000072656", "map_id": "ENSBTAT00000072656", "name": "COASY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042655", "map_id": "none", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10042652", "map_id": "A6QPI5", "name": "SLC25A16", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000031344", "map_id": "ENSBTAT00000031344", "name": "SLC25A16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041744", "map_id": "none", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196767", "map_id": "CHEBI:16858", "name": "PPANT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041765", "map_id": "none", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041762", "map_id": "none", "name": "3xPPCDC:3xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MNK4", "map_id": "A0A3Q1MNK4", "name": "PPCDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076608", "map_id": "ENSBTAT00000076608", "name": "PPCDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053048", "map_id": "none", "name": "Dimerization of p-IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039550", "map_id": "A0A3Q1MWF9", "name": "phospho-IRF7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000075628", "map_id": "ENSBTAT00000075628", "name": "phospho-IRF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039554", "map_id": "none", "name": "p-2S-IRF7:p-2S-IRF7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MWF9", "map_id": "A0A3Q1MWF9", "name": "phospho-IRF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053046", "map_id": "none", "name": "Translocation of p-IRF7:p-IRF7 to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10040193", "map_id": "none", "name": "2xp-S477,S479-IRF7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10037203", "map_id": "none", "name": "Formation of DSIF:NELF:early elongation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037126", "map_id": "none", "name": "NELF complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6QQS5", "map_id": "A6QQS5", "name": "NELFA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023832", "map_id": "ENSBTAT00000023832", "name": "NELFA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5S2", "map_id": "G5E5S2", "name": "NELFB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029144", "map_id": "ENSBTAT00000029144", "name": "NELFB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MW69", "map_id": "F1MW69", "name": "NELFCD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025006", "map_id": "ENSBTAT00000025006", "name": "NELFCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037171", "map_id": "none", "name": "RNA Pol II (hypophosphorylated) complex bound to DSIF protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N7E3", "map_id": "A0A3Q1N7E3", "name": "SUPT4H1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071171", "map_id": "ENSBTAT00000071171", "name": "SUPT4H1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQ76", "map_id": "A0A3Q1MQ76", "name": "phospho-SUPT5H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070366", "map_id": "ENSBTAT00000070366", "name": "phospho-SUPT5H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMM0", "map_id": "E1BMM0", "name": "NCBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061170", "map_id": "ENSBTAT00000061170", "name": "NCBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBJ1", "map_id": "Q3ZBJ1", "name": "NCBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011684", "map_id": "ENSBTAT00000011684", "name": "NCBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQ91", "map_id": "Q1JQ91", "name": "POLR2D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074897", "map_id": "ENSBTAT00000074897", "name": "POLR2D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9B8", "map_id": "Q5E9B8", "name": "POLR2G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012481", "map_id": "ENSBTAT00000012481", "name": "POLR2G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA53", "map_id": "Q5EA53", "name": "GTF2F1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027988", "map_id": "ENSBTAT00000027988", "name": "GTF2F1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2T9L9", "map_id": "Q2T9L9", "name": "GTF2F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078070", "map_id": "ENSBTAT00000078070", "name": "GTF2F2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32P79", "map_id": "Q32P79", "name": "POLR2J", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007165", "map_id": "ENSBTAT00000007165", "name": "POLR2J", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZY8", "map_id": "G3MZY8", "name": "phospho-POLR2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069267", "map_id": "ENSBTAT00000069267", "name": "phospho-POLR2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0Q3", "map_id": "Q3T0Q3", "name": "POLR2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002420", "map_id": "ENSBTAT00000002420", "name": "POLR2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MWS0", "map_id": "A0A3Q1MWS0", "name": "CTDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080412", "map_id": "ENSBTAT00000080412", "name": "CTDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30595", "map_id": "none", "name": "NTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10037173", "map_id": "none", "name": "DSIF:NELF:early elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10037205", "map_id": "none", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037169", "map_id": "none", "name": "RNA Pol II (hypophosphorylated):capped pre-mRNA complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10037137", "map_id": "none", "name": "DSIF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086136", "map_id": "none", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane" }, { "id": "species_10086105", "map_id": "none", "name": "GGC-RAB1:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MNB1", "map_id": "A0A3Q1MNB1", "name": "GDI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080327", "map_id": "ENSBTAT00000080327", "name": "GDI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPF1", "map_id": "A0A3Q1MPF1", "name": "GDI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2I0", "map_id": "F1N2I0", "name": "CHML", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014310", "map_id": "ENSBTAT00000014310", "name": "CHML", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21856", "map_id": "P21856", "name": "GDI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016093", "map_id": "ENSBTAT00000016093", "name": "GDI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MS24", "map_id": "F1MS24", "name": "CHM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012631", "map_id": "ENSBTAT00000012631", "name": "CHM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086115", "map_id": "none", "name": "GGC-RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10085883", "map_id": "none", "name": "GDIs,CHMs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10086133", "map_id": "none", "name": "TRAPPCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N5L8", "map_id": "A0A3Q1N5L8", "name": "TRAPPC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086931", "map_id": "ENSBTAT00000086931", "name": "TRAPPC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MK52", "map_id": "A0A3Q1MK52", "name": "TRAPPC12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082010", "map_id": "ENSBTAT00000082010", "name": "TRAPPC12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXL8", "map_id": "F1MXL8", "name": "TRAPPC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009769", "map_id": "ENSBTAT00000009769", "name": "TRAPPC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085932", "map_id": "none", "name": "DENND4s exchange GTP for GDP on RAB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane" }, { "id": "species_10085911", "map_id": "none", "name": "GGC-RAB10:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QLS9", "map_id": "A6QLS9", "name": "RAB10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001303", "map_id": "ENSBTAT00000001303", "name": "RAB10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085915", "map_id": "none", "name": "GGC-RAB10:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "species_10085929", "map_id": "none", "name": "DENND4s", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BJE1", "map_id": "E1BJE1", "name": "DENND4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022733", "map_id": "ENSBTAT00000022733", "name": "DENND4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N377", "map_id": "F1N377", "name": "DENND4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034026", "map_id": "ENSBTAT00000034026", "name": "DENND4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NBE4", "map_id": "A0A3Q1NBE4", "name": "DENND4C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073212", "map_id": "ENSBTAT00000073212", "name": "DENND4C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086097", "map_id": "none", "name": "RAB31 GEFs exchange GTP for GDP on RAB31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10086086", "map_id": "none", "name": "GGC-RAB31:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DC2", "map_id": "Q08DC2", "name": "RAB31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075871", "map_id": "ENSBTAT00000075871", "name": "RAB31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086090", "map_id": "none", "name": "GGC-RAB31:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_10086094", "map_id": "G5E5D0", "name": "RIN3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000013748", "map_id": "ENSBTAT00000013748", "name": "RIN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086209", "map_id": "none", "name": "DENND5A,B exchange GTP for GDP on RAB39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10086188", "map_id": "none", "name": "GGC-RAB39:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3X7D3", "map_id": "G3X7D3", "name": "RAB39A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024288", "map_id": "ENSBTAT00000024288", "name": "RAB39A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086196", "map_id": "none", "name": "GGC-RAB39:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10086206", "map_id": "none", "name": "DENND5A,B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MUN3", "map_id": "A0A3Q1MUN3", "name": "DENND5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069720", "map_id": "ENSBTAT00000069720", "name": "DENND5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQ87", "map_id": "F1MQ87", "name": "DENND5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027075", "map_id": "ENSBTAT00000027075", "name": "DENND5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086019", "map_id": "none", "name": "DENND6A,B exchange GTP for GDP on RAB14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10086008", "map_id": "none", "name": "GGC-RAB14:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZBG1", "map_id": "Q3ZBG1", "name": "RAB14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023671", "map_id": "ENSBTAT00000023671", "name": "RAB14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086012", "map_id": "none", "name": "GGC-RAB14:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "species_10086016", "map_id": "A0A3Q1M6D4", "name": "DENND6B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000067401", "map_id": "ENSBTAT00000067401", "name": "DENND6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085988", "map_id": "none", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane" }, { "id": "species_10085979", "map_id": "none", "name": "GCC-RAB12:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QPX8", "map_id": "A6QPX8", "name": "RAB12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013671", "map_id": "ENSBTAT00000013671", "name": "RAB12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085983", "map_id": "none", "name": "GGC-RAB12:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "species_10085985", "map_id": "none", "name": "DENND3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MCL3", "map_id": "A0A3Q1MCL3", "name": "phospho-DENND3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087265", "map_id": "ENSBTAT00000087265", "name": "phospho-DENND3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086054", "map_id": "none", "name": "RAB21 GEFs exchange GTP for GDP on RAB21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10086037", "map_id": "none", "name": "GGC-RAB21:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MPP1", "map_id": "F1MPP1", "name": "RAB21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025807", "map_id": "ENSBTAT00000025807", "name": "RAB21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086041", "map_id": "none", "name": "GGC-RAB21:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_10086051", "map_id": "none", "name": "RAB21 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4Y7", "map_id": "A0A3Q1M4Y7", "name": "SBF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075635", "map_id": "ENSBTAT00000075635", "name": "SBF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M373", "map_id": "A0A3Q1M373", "name": "SBF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078087", "map_id": "ENSBTAT00000078087", "name": "SBF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086182", "map_id": "none", "name": "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5668575", "compartment_display": "melanosome membrane" }, { "id": "species_10086161", "map_id": "none", "name": "RAB32,RAB38:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BA60", "map_id": "E1BA60", "name": "RAB32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012905", "map_id": "ENSBTAT00000012905", "name": "RAB32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9C0", "map_id": "E1B9C0", "name": "RAB38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020971", "map_id": "ENSBTAT00000020971", "name": "RAB38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086169", "map_id": "none", "name": "RAB32,RAB38:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5668575", "compartment_display": "melanosome membrane", "complex": "true" }, { "id": "species_10086179", "map_id": "none", "name": "HPS1:HPS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B7M9", "map_id": "E1B7M9", "name": "HPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056415", "map_id": "ENSBTAT00000056415", "name": "HPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N720", "map_id": "A0A3Q1N720", "name": "HPS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071404", "map_id": "ENSBTAT00000071404", "name": "HPS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048567", "map_id": "none", "name": "Na+/H+ exchanger transport (at cell membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048564", "map_id": "none", "name": "SLC9A1-5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BB11", "map_id": "E1BB11", "name": "SLC9A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002235", "map_id": "ENSBTAT00000002235", "name": "SLC9A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MU00", "map_id": "F1MU00", "name": "SLC9A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006073", "map_id": "ENSBTAT00000006073", "name": "SLC9A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8Y0", "map_id": "E1B8Y0", "name": "SLC9A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054801", "map_id": "ENSBTAT00000054801", "name": "SLC9A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048550", "map_id": "none", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_425978", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_425971", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_10048547", "map_id": "A0A3Q1M7D5", "name": "LOC112445029", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "ENSBTAT00000073706", "map_id": "ENSBTAT00000073706", "name": "LOC112445029", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058841", "map_id": "none", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498733", "map_id": "CHEBI:28914", "name": "1-acyl LPI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10058838", "map_id": "Q0VCY6", "name": "MBOAT7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000068283", "map_id": "ENSBTAT00000068283", "name": "MBOAT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059000", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058905", "map_id": "none", "name": "PLA2G2A:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10059851", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_426658", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602420", "map_id": "CHEBI:28914", "name": "1-acyl LPI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10058874", "map_id": "none", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498737", "map_id": "CHEBI:62746", "name": "2-acyl LPI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058975", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058972", "map_id": "none", "name": "PLA2(11)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10059026", "map_id": "none", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059023", "map_id": "none", "name": "PLA2(13)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10048682", "map_id": "none", "name": "MBD2 binds methylcytosine in chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035250", "map_id": "none", "name": "Chromatin with H3K9me2, 5mC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10035235", "map_id": "G5E683", "name": "MBD2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10048717", "map_id": "none", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10048700", "map_id": "none", "name": "Chromatin with acetylated H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427523", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_427497", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044309", "map_id": "none", "name": "Chromatin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427498", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10048714", "map_id": "none", "name": "eNoSC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BJI1", "map_id": "E1BJI1", "name": "RRP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039795", "map_id": "ENSBTAT00000039795", "name": "RRP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQB8", "map_id": "F1MQB8", "name": "SIRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018630", "map_id": "ENSBTAT00000018630", "name": "SIRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048720", "map_id": "none", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10048712", "map_id": "none", "name": "Chromatin (H3K9me2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044361", "map_id": "none", "name": "Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044357", "map_id": "none", "name": "PRC2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3SZ25", "map_id": "Q3SZ25", "name": "EED", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010324", "map_id": "ENSBTAT00000010324", "name": "EED", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSK4", "map_id": "A0A3Q1MSK4", "name": "EZH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084115", "map_id": "ENSBTAT00000084115", "name": "EZH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M792", "map_id": "A0A3Q1M792", "name": "SUZ12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077887", "map_id": "ENSBTAT00000077887", "name": "SUZ12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHL3", "map_id": "Q3MHL3", "name": "RBBP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007758", "map_id": "ENSBTAT00000007758", "name": "RBBP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPJ7", "map_id": "A0A3Q1LPJ7", "name": "MTF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083404", "map_id": "ENSBTAT00000083404", "name": "MTF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6Y2", "map_id": "F1N6Y2", "name": "PHF19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022557", "map_id": "ENSBTAT00000022557", "name": "PHF19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044359", "map_id": "none", "name": "PRC2:Chromatin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044381", "map_id": "none", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044378", "map_id": "none", "name": "PRC2:Chromatin (H3K27me3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044333", "map_id": "none", "name": "PRC2 recruits DNA methyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044307", "map_id": "none", "name": "DNMT1,3A,3B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M9H4", "map_id": "A0A3Q1M9H4", "name": "DNMT3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086443", "map_id": "ENSBTAT00000086443", "name": "DNMT3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVT5", "map_id": "A0A3Q1LVT5", "name": "DNMT3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069734", "map_id": "ENSBTAT00000069734", "name": "DNMT3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DII9", "map_id": "A0A452DII9", "name": "DNMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003549", "map_id": "ENSBTAT00000003549", "name": "DNMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044329", "map_id": "none", "name": "PRC2 Core:Chromatin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10044331", "map_id": "none", "name": "DNMT1,3A,3B:PRC2:Chromatin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044390", "map_id": "none", "name": "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044387", "map_id": "none", "name": "DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10070700", "map_id": "none", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5221062", "map_id": "none", "name": "DNA containing 5-fC", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10036698", "map_id": "A0A3Q1LSS4", "name": "TDG", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000072242", "map_id": "ENSBTAT00000072242", "name": "TDG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036706", "map_id": "none", "name": "TDG:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LSS4", "map_id": "A0A3Q1LSS4", "name": "TDG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5221065", "map_id": "CHEBI:76794", "name": "5-fC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10070702", "map_id": "none", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5220996", "map_id": "none", "name": "DNA containing 5-caC", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_5221064", "map_id": "CHEBI:76793", "name": "5-caC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10071065", "map_id": "none", "name": "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113560", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2485002", "map_id": "CHEBI:15346", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071014", "map_id": "none", "name": "Nucleosome (H3K9ac)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10071062", "map_id": "none", "name": "B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A5PJQ1", "map_id": "A5PJQ1", "name": "DEK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017097", "map_id": "ENSBTAT00000017097", "name": "DEK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B6X6", "map_id": "E1B6X6", "name": "BAZ1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072070", "map_id": "ENSBTAT00000072070", "name": "BAZ1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKX3", "map_id": "E1BKX3", "name": "MYBBP1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009771", "map_id": "ENSBTAT00000009771", "name": "MYBBP1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX61", "map_id": "F1MX61", "name": "SF3B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011734", "map_id": "ENSBTAT00000011734", "name": "SF3B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M384", "map_id": "A0A3Q1M384", "name": "SMARCA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070441", "map_id": "ENSBTAT00000070441", "name": "SMARCA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QHI8", "map_id": "F6QHI8", "name": "DDX21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019351", "map_id": "ENSBTAT00000019351", "name": "DDX21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQD6", "map_id": "Q1JQD6", "name": "TAF1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043676", "map_id": "ENSBTAT00000043676", "name": "TAF1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32LB6", "map_id": "Q32LB6", "name": "TAF1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004611", "map_id": "ENSBTAT00000004611", "name": "TAF1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUD5", "map_id": "F1MUD5", "name": "TAF1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056158", "map_id": "ENSBTAT00000056158", "name": "TAF1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065336", "map_id": "none", "name": "LTBP1, LTBP3 bind TGF-Beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065332", "map_id": "none", "name": "TGF-beta-3:LAP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10065308", "map_id": "A0A3Q1LJU9", "name": "LTBP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000075583", "map_id": "ENSBTAT00000075583", "name": "LTBP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065334", "map_id": "none", "name": "LTBP1, LTBP3:TGF betas:LAPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LJU9", "map_id": "A0A3Q1LJU9", "name": "LTBP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065435", "map_id": "none", "name": "Fibrillins bind BMPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065431", "map_id": "none", "name": "BMP2,4,7,10,GF5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MLT0", "map_id": "F1MLT0", "name": "BMP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060945", "map_id": "ENSBTAT00000060945", "name": "BMP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8X7", "map_id": "E1B8X7", "name": "BMP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001312", "map_id": "ENSBTAT00000001312", "name": "BMP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MT44", "map_id": "F1MT44", "name": "GDF5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005807", "map_id": "ENSBTAT00000005807", "name": "GDF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065433", "map_id": "none", "name": "Fibrillins:BMP2,4,7,10,GF5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10064435", "map_id": "none", "name": "Elastic fibres bind associated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064421", "map_id": "none", "name": "Elastic fibre:Fibulins:Emilins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1MN12", "map_id": "A0A3Q1MN12", "name": "EFEMP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070645", "map_id": "ENSBTAT00000070645", "name": "EFEMP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLS8", "map_id": "E1BLS8", "name": "EMILIN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015049", "map_id": "ENSBTAT00000015049", "name": "EMILIN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064431", "map_id": "none", "name": "Elastic fibre-asociated proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P55918", "map_id": "P55918", "name": "MFAP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008130", "map_id": "ENSBTAT00000008130", "name": "MFAP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA98", "map_id": "Q5EA98", "name": "MFAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022877", "map_id": "ENSBTAT00000022877", "name": "MFAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064433", "map_id": "none", "name": "Elastic fibre with associated proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10063839", "map_id": "none", "name": "Fibrillin microfibril assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10063825", "map_id": "none", "name": "Fibrillin peptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10064437", "map_id": "none", "name": "Tropoelastin forms aggregate globules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059655", "map_id": "A0A3Q1MEV3", "name": "ELN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10063809", "map_id": "none", "name": "Tropoelastin aggregate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10067346", "map_id": "none", "name": "TRPM4,5 transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067343", "map_id": "none", "name": "TRPM4,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BNX9", "map_id": "E1BNX9", "name": "TRPM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008077", "map_id": "ENSBTAT00000008077", "name": "TRPM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0Y5", "map_id": "A0A3Q1M0Y5", "name": "TRPM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075032", "map_id": "ENSBTAT00000075032", "name": "TRPM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092050", "map_id": "none", "name": "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092047", "map_id": "none", "name": "TRPA1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E522", "map_id": "G5E522", "name": "TRPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002668", "map_id": "ENSBTAT00000002668", "name": "TRPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067330", "map_id": "none", "name": "p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BKA8", "map_id": "E1BKA8", "name": "phospho-RIPK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024511", "map_id": "ENSBTAT00000024511", "name": "phospho-RIPK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGC6", "map_id": "E1BGC6", "name": "phospho-MLKL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082389", "map_id": "ENSBTAT00000082389", "name": "phospho-MLKL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067332", "map_id": "none", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067306", "map_id": "none", "name": "TRPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MY82", "map_id": "G3MY82", "name": "MCOLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065500", "map_id": "ENSBTAT00000065500", "name": "MCOLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPC8", "map_id": "E1BPC8", "name": "TRPM8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019509", "map_id": "ENSBTAT00000019509", "name": "TRPM8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2S2", "map_id": "G3N2S2", "name": "MCOLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066065", "map_id": "ENSBTAT00000066065", "name": "MCOLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA32", "map_id": "Q5EA32", "name": "TRPV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003922", "map_id": "ENSBTAT00000003922", "name": "TRPV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M893", "map_id": "A0A3Q1M893", "name": "TRPM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074148", "map_id": "ENSBTAT00000074148", "name": "TRPM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPF0", "map_id": "F1MPF0", "name": "TRPM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044081", "map_id": "ENSBTAT00000044081", "name": "TRPM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79100", "map_id": "P79100", "name": "TRPC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065392", "map_id": "ENSBTAT00000065392", "name": "TRPC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAN3", "map_id": "E1BAN3", "name": "TRPV6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033438", "map_id": "ENSBTAT00000033438", "name": "TRPV6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N232", "map_id": "F1N232", "name": "TRPC4AP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068680", "map_id": "ENSBTAT00000068680", "name": "TRPC4AP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDG0", "map_id": "E1BDG0", "name": "MCOLN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022589", "map_id": "ENSBTAT00000022589", "name": "MCOLN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCP0", "map_id": "E1BCP0", "name": "TRPV4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085000", "map_id": "ENSBTAT00000085000", "name": "TRPV4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B6Y9", "map_id": "E1B6Y9", "name": "TRPV5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002485", "map_id": "ENSBTAT00000002485", "name": "TRPV5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039604", "map_id": "none", "name": "Protons are translocated from the intermembrane space to the matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10039233", "map_id": "none", "name": "UCP dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "E1BME0", "map_id": "E1BME0", "name": "SLC25A27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021691", "map_id": "ENSBTAT00000021691", "name": "SLC25A27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIJ0", "map_id": "Q2KIJ0", "name": "SLC25A14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021633", "map_id": "ENSBTAT00000021633", "name": "SLC25A14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZI5", "map_id": "Q3SZI5", "name": "UCP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004810", "map_id": "ENSBTAT00000004810", "name": "UCP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_170037", "map_id": "none", "name": "Purine nucleotide", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10039240", "map_id": "none", "name": "FA anion flip-flops to the opposite surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10039235", "map_id": "none", "name": "FA anion:UCP dimer \"head-in\" complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_166216", "map_id": "CHEBI:28868", "name": "Fatty Acid anion \"head-out\"", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10039237", "map_id": "none", "name": "FA anion:UCP dimer \"head-out\" complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10039242", "map_id": "none", "name": "FA anion diffuses laterally to UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_166213", "map_id": "CHEBI:28868", "name": "Fatty Acid anion \"head-in\"", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10039254", "map_id": "none", "name": "The FA anion diffuses away laterally from UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "reaction_10073400", "map_id": "none", "name": "JMJD6 demethylates Me2R3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073398", "map_id": "none", "name": "Me2R3-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066894", "map_id": "none", "name": "MeR3-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_29478", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069751", "map_id": "A0A452DJR2", "name": "JMJD6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000025492", "map_id": "ENSBTAT00000025492", "name": "JMJD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066651", "map_id": "none", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066642", "map_id": "none", "name": "MeK5-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066644", "map_id": "none", "name": "Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066648", "map_id": "A0A3Q1LGR3", "name": "KDM1B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000076721", "map_id": "ENSBTAT00000076721", "name": "KDM1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073402", "map_id": "none", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069756", "map_id": "none", "name": "Me2K5-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10069754", "map_id": "none", "name": "JMJD6 demethylates MeR3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10073404", "map_id": "none", "name": "JMJD6 demethylates MeR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070273", "map_id": "none", "name": "Homologues of MeR4-HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10035060", "map_id": "none", "name": "Homologues of HIST1H4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073406", "map_id": "none", "name": "JMJD6 demethylates Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070419", "map_id": "none", "name": "Homologues of Me2sR4-HIST1H4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10069747", "map_id": "none", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069723", "map_id": "none", "name": "MeK10-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069744", "map_id": "E1BFC2", "name": "KDM3A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000080313", "map_id": "ENSBTAT00000080313", "name": "KDM3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073394", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069811", "map_id": "none", "name": "Me3K10-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069721", "map_id": "none", "name": "Me2K10-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069737", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MT70", "map_id": "A0A3Q1MT70", "name": "KDM4C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078784", "map_id": "ENSBTAT00000078784", "name": "KDM4C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB12", "map_id": "E1BB12", "name": "KDM4D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002234", "map_id": "ENSBTAT00000002234", "name": "KDM4D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPL5", "map_id": "E1BPL5", "name": "KDM4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002687", "map_id": "ENSBTAT00000002687", "name": "KDM4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MI23", "map_id": "A0A3Q1MI23", "name": "RIOX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070121", "map_id": "ENSBTAT00000070121", "name": "RIOX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073396", "map_id": "none", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072792", "map_id": "none", "name": "Me3K28-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069777", "map_id": "none", "name": "Me2K28-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069793", "map_id": "none", "name": "KDM6A,KDM6B,KDM6C,KDM7A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3N2E9", "map_id": "G3N2E9", "name": "KDM6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063826", "map_id": "ENSBTAT00000063826", "name": "KDM6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N346", "map_id": "G3N346", "name": "KDM6B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063022", "map_id": "ENSBTAT00000063022", "name": "KDM6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069719", "map_id": "none", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069712", "map_id": "none", "name": "MeK37-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10069716", "map_id": "E1BPL5", "name": "KDM4A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10069769", "map_id": "none", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069766", "map_id": "none", "name": "KDM5A-D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MZ57", "map_id": "A0A3Q1MZ57", "name": "KDM5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071767", "map_id": "ENSBTAT00000071767", "name": "KDM5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUR2", "map_id": "F1MUR2", "name": "KDM5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028871", "map_id": "ENSBTAT00000028871", "name": "KDM5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073384", "map_id": "none", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070949", "map_id": "none", "name": "Me3K5-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10069740", "map_id": "none", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10073380", "map_id": "none", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072735", "map_id": "none", "name": "Me2K37-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10069796", "map_id": "none", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069785", "map_id": "none", "name": "MeK28-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10073382", "map_id": "none", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10069937", "map_id": "none", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069934", "map_id": "none", "name": "SETD3, SETD7, WHSC1L1, Core MLL complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MUT0", "map_id": "F1MUT0", "name": "SETD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004658", "map_id": "ENSBTAT00000004658", "name": "SETD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NKU6", "map_id": "Q2NKU6", "name": "DPY30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012183", "map_id": "ENSBTAT00000012183", "name": "DPY30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLX2", "map_id": "E1BLX2", "name": "SETD1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070677", "map_id": "ENSBTAT00000070677", "name": "SETD1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHA1", "map_id": "F1MHA1", "name": "KMT2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024084", "map_id": "ENSBTAT00000024084", "name": "KMT2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072752", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069843", "map_id": "E1BM66", "name": "NSD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000034204", "map_id": "ENSBTAT00000034204", "name": "NSD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072755", "map_id": "none", "name": "PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044337", "map_id": "none", "name": "PRC2 (EZH2) Core:AEBP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10069939", "map_id": "none", "name": "ATF7IP binds SETDB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069830", "map_id": "E1BKH5", "name": "SETDB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000000107", "map_id": "ENSBTAT00000000107", "name": "SETDB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069834", "map_id": "A0A3Q1M7L9", "name": "ATF7IP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000086218", "map_id": "ENSBTAT00000086218", "name": "ATF7IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069836", "map_id": "none", "name": "ATF7IP:SETDB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M7L9", "map_id": "A0A3Q1M7L9", "name": "ATF7IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKH5", "map_id": "E1BKH5", "name": "SETDB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070962", "map_id": "none", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070959", "map_id": "none", "name": "Core MLL complex, SMYD3, PRDM9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0P5C5", "map_id": "Q0P5C5", "name": "SMYD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047138", "map_id": "ENSBTAT00000047138", "name": "SMYD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X834", "map_id": "G3X834", "name": "PRDM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056084", "map_id": "ENSBTAT00000056084", "name": "PRDM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070404", "map_id": "none", "name": "Me2aR3-histone H3, MeR3-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10072725", "map_id": "none", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072722", "map_id": "none", "name": "WHSC1L1, Core MLL complex, SMYD3, SETD3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10072788", "map_id": "none", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072771", "map_id": "none", "name": "Me2K80-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10072786", "map_id": "none", "name": "Me3K80-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10072775", "map_id": "A0A3Q1LX03", "name": "DOT1L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000082174", "map_id": "ENSBTAT00000082174", "name": "DOT1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072823", "map_id": "none", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072800", "map_id": "none", "name": "Homologues of Me2K21-HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10072821", "map_id": "none", "name": "Homologues of Me3K21-HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10072810", "map_id": "none", "name": "SUV420H1,SUV420H2,(SMYD3)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M6A7", "map_id": "A0A3Q1M6A7", "name": "KMT5C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075432", "map_id": "ENSBTAT00000075432", "name": "KMT5C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MID6", "map_id": "A0A3Q1MID6", "name": "KMT5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070396", "map_id": "ENSBTAT00000070396", "name": "KMT5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069846", "map_id": "none", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10072790", "map_id": "none", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072763", "map_id": "none", "name": "MeK80-histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10072778", "map_id": "none", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10072813", "map_id": "none", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10064889", "map_id": "none", "name": "Homologues of MeK-HIST1H4A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10072655", "map_id": "none", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072636", "map_id": "none", "name": "Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072642", "map_id": "none", "name": "MeK10-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072652", "map_id": "none", "name": "PRDM16, MECOM", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MTF1", "map_id": "F1MTF1", "name": "PRDM16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025245", "map_id": "ENSBTAT00000025245", "name": "PRDM16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069838", "map_id": "none", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069825", "map_id": "none", "name": "SUV39H1, SUV39H2, SETDB1, SETDB2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N6Y5", "map_id": "F1N6Y5", "name": "SETD1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022553", "map_id": "ENSBTAT00000022553", "name": "SETD1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXG0", "map_id": "F1MXG0", "name": "SETDB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009641", "map_id": "ENSBTAT00000009641", "name": "SETDB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ38", "map_id": "A0A452DJ38", "name": "SUV39H2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013472", "map_id": "ENSBTAT00000013472", "name": "SUV39H2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072750", "map_id": "none", "name": "SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072743", "map_id": "none", "name": "Me3K37-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10072747", "map_id": "A0A3Q1MJ95", "name": "SETD2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000084416", "map_id": "ENSBTAT00000084416", "name": "SETD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068699", "map_id": "none", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068652", "map_id": "none", "name": "Acetylated core histone octamer", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10068658", "map_id": "none", "name": "Core histone octamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5566518", "map_id": "CHEBI:30089", "name": "acetate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10068694", "map_id": "none", "name": "Sin3A complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MMC8", "map_id": "A0A3Q1MMC8", "name": "SAP18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063281", "map_id": "ENSBTAT00000063281", "name": "SAP18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B806", "map_id": "E1B806", "name": "SAP30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020692", "map_id": "ENSBTAT00000020692", "name": "SAP30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VC01", "map_id": "Q0VC01", "name": "HDAC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075111", "map_id": "ENSBTAT00000075111", "name": "HDAC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MC43", "map_id": "A0A3Q1MC43", "name": "ARID4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075576", "map_id": "ENSBTAT00000075576", "name": "ARID4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1LZE0", "map_id": "Q1LZE0", "name": "BRMS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023526", "map_id": "ENSBTAT00000023526", "name": "BRMS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGK1", "map_id": "E1BGK1", "name": "ARID4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025155", "map_id": "ENSBTAT00000025155", "name": "ARID4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFL5", "map_id": "F1MFL5", "name": "SAP30L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005222", "map_id": "ENSBTAT00000005222", "name": "SAP30L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068697", "map_id": "none", "name": "HDAC1:2-containing complex:HDAC2 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10068844", "map_id": "none", "name": "HDAC8 deacetylates histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044720", "map_id": "A0A3Q1MDJ2", "name": "HDAC8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000070733", "map_id": "ENSBTAT00000070733", "name": "HDAC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091745", "map_id": "none", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9679795", "map_id": "none", "name": "HDAC2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10068725", "map_id": "none", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068722", "map_id": "none", "name": "HDAC3-containing complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:57627", "map_id": "CHEBI:57627", "name": "CHEBI:57627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068569", "map_id": "none", "name": "EP300 acetylates histone H2A, H2B, H3, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068132", "map_id": "none", "name": "Histone H2A, H2B, H3, H4", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10068566", "map_id": "none", "name": "AcK-histone H2A, H2B, H3, H4", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10067596", "map_id": "none", "name": "MSL acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10067575", "map_id": "none", "name": "Homologues of AcK17-HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10067593", "map_id": "none", "name": "MSL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MP98", "map_id": "F1MP98", "name": "KAT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013893", "map_id": "ENSBTAT00000013893", "name": "KAT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRF9", "map_id": "F1MRF9", "name": "MSL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000991", "map_id": "ENSBTAT00000000991", "name": "MSL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFW0", "map_id": "E1BFW0", "name": "MSL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030541", "map_id": "ENSBTAT00000030541", "name": "MSL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071886", "map_id": "none", "name": "NCOA1(868-1441) binds PAX3(1-319)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071878", "map_id": "G3N0C2", "name": "NCOA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071882", "map_id": "F1MTX0", "name": "PAX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000013131", "map_id": "ENSBTAT00000013131", "name": "PAX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071884", "map_id": "none", "name": "NCOA1(868-1441):PAX3(1-319)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MTX0", "map_id": "F1MTX0", "name": "PAX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070409", "map_id": "none", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070394", "map_id": "none", "name": "MeR3-histone H3, Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070406", "map_id": "none", "name": "CARM1, PRMT6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LQR4", "map_id": "A0A3Q1LQR4", "name": "CARM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066577", "map_id": "ENSBTAT00000066577", "name": "CARM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9L5", "map_id": "Q5E9L5", "name": "PRMT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009750", "map_id": "ENSBTAT00000009750", "name": "PRMT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070377", "map_id": "none", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070328", "map_id": "none", "name": "MeR4-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070374", "map_id": "none", "name": "Me2aR4-histone H2A, MeR4-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070277", "map_id": "Q5E9L5", "name": "PRMT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10070520", "map_id": "none", "name": "DNMT3A binds Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044297", "map_id": "A0A3Q1M9H4", "name": "DNMT3A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070518", "map_id": "none", "name": "Me2R4-HIST1H4:DNMT3A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073416", "map_id": "none", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073414", "map_id": "none", "name": "Homologues of Me2aR4-HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10070279", "map_id": "none", "name": "PRMT1,PRMT6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MR38", "map_id": "A0A3Q1MR38", "name": "PRMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068896", "map_id": "ENSBTAT00000068896", "name": "PRMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070392", "map_id": "none", "name": "CARM1 methylates arginine-18 (H3R17) of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070379", "map_id": "none", "name": "MeR18-histone H3, Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070389", "map_id": "none", "name": "Me2aR18-histone H3, MeR18-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10047781", "map_id": "A0A3Q1LQR4", "name": "CARM1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10070282", "map_id": "none", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10070896", "map_id": "none", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070848", "map_id": "none", "name": "MeR30-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070894", "map_id": "none", "name": "Me2aR30-histone H2A, MeR30-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10070757", "map_id": "none", "name": "CARM1 methylates arginine-27 of histone H3 (H3R26)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070745", "map_id": "none", "name": "MeR27-histone H3, Histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070755", "map_id": "none", "name": "Me2aR27-histone H3, MeR27-histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10070516", "map_id": "none", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10070467", "map_id": "none", "name": "MeR12-histone H2A, Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10070513", "map_id": "none", "name": "Me2aR12-histone H2A, MeR12-histone H2A", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066655", "map_id": "A0A3Q1MR38", "name": "PRMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10056383", "map_id": "none", "name": "PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1183111", "map_id": "none", "name": "Protein-L-arginine", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1183191", "map_id": "none", "name": "Protein-L-citrulline", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056380", "map_id": "none", "name": "PADIs:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QLC1", "map_id": "A6QLC1", "name": "PADI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015977", "map_id": "ENSBTAT00000015977", "name": "PADI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N048", "map_id": "F1N048", "name": "PADI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004411", "map_id": "ENSBTAT00000004411", "name": "PADI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD46", "map_id": "E1BD46", "name": "PADI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015978", "map_id": "ENSBTAT00000015978", "name": "PADI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCN3", "map_id": "E1BCN3", "name": "PADI4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015991", "map_id": "ENSBTAT00000015991", "name": "PADI4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066966", "map_id": "none", "name": "PADI4 deiminates Histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066920", "map_id": "none", "name": "MeR3-replicative histone H3, MeR9-replicative histone H3, MeR18-replicative histone H3, Me27-replicatve histone H3", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066951", "map_id": "none", "name": "Cit3-replicative histone H3, Cit9-replicative histone H3, Cit18-replicative histone H3, Cit27-replicative histone H3", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_76230", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066963", "map_id": "none", "name": "PADI4,(PADI1,PADI2,PADI3, PADI6)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092108", "map_id": "none", "name": "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane" }, { "id": "species_10092095", "map_id": "none", "name": "Ub:UBE2D1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10092091", "map_id": "none", "name": "SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "P35833", "map_id": "P35833", "name": "CSF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028610", "map_id": "ENSBTAT00000028610", "name": "CSF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MYA3", "map_id": "A0A3Q1MYA3", "name": "phospho-HCK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072313", "map_id": "ENSBTAT00000072313", "name": "phospho-HCK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055212", "map_id": "Q0P5F4", "name": "RNF7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055148", "map_id": "Q3SZ32", "name": "TCEB2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055146", "map_id": "Q2KII4", "name": "ELOC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055162", "map_id": "A0A3Q1MXH0", "name": "CUL5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092105", "map_id": "none", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10092257", "map_id": "none", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane" }, { "id": "species_10092255", "map_id": "none", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10073690", "map_id": "none", "name": "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073673", "map_id": "none", "name": "Non-canonical NF-kB initiating TNFRSF memebers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BL08", "map_id": "E1BL08", "name": "MAP3K14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009316", "map_id": "ENSBTAT00000009316", "name": "MAP3K14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTC1", "map_id": "F1MTC1", "name": "TNFRSF11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009960", "map_id": "ENSBTAT00000009960", "name": "TNFRSF11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIP0", "map_id": "E1BIP0", "name": "TNFSF11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011745", "map_id": "ENSBTAT00000011745", "name": "TNFSF11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX43", "map_id": "F1MX43", "name": "TNFSF12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045584", "map_id": "ENSBTAT00000045584", "name": "TNFSF12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LHY0", "map_id": "A0A3Q1LHY0", "name": "TNFRSF12A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081383", "map_id": "ENSBTAT00000081383", "name": "TNFRSF12A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJD0", "map_id": "F1MJD0", "name": "TNFRSF13C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037660", "map_id": "ENSBTAT00000037660", "name": "TNFRSF13C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "B0LKN7", "map_id": "B0LKN7", "name": "TNFSF13B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065347", "map_id": "ENSBTAT00000065347", "name": "TNFSF13B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQ46", "map_id": "A6QQ46", "name": "LTBR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020355", "map_id": "ENSBTAT00000020355", "name": "LTBR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06600", "map_id": "Q06600", "name": "LTA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000018", "map_id": "ENSBTAT00000000018", "name": "LTA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK50", "map_id": "E1BK50", "name": "LTB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027554", "map_id": "ENSBTAT00000027554", "name": "LTB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0K4", "map_id": "F1N0K4", "name": "TNFSF14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045141", "map_id": "ENSBTAT00000045141", "name": "TNFSF14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073687", "map_id": "none", "name": "TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074280", "map_id": "none", "name": "TNFRSF6B binds TNFSF6,14,15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074276", "map_id": "none", "name": "TNFSF6,14,15", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BF06", "map_id": "E1BF06", "name": "TNFSF15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036452", "map_id": "ENSBTAT00000036452", "name": "TNFSF15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074270", "map_id": "A6QPW7", "name": "TNFRSF6B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000028109", "map_id": "ENSBTAT00000028109", "name": "TNFRSF6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074278", "map_id": "none", "name": "TNFRSF6B:TNFSF6,14,15", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QPW7", "map_id": "A6QPW7", "name": "TNFRSF6B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074266", "map_id": "none", "name": "TNFSF18 binds TNFRSF18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074262", "map_id": "Q08DT5", "name": "TNFSF18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000064406", "map_id": "ENSBTAT00000064406", "name": "TNFSF18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074258", "map_id": "A0A3Q1M9X1", "name": "TNFRSF18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000079425", "map_id": "ENSBTAT00000079425", "name": "TNFRSF18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074264", "map_id": "none", "name": "TNFSF18:TNFRSF18", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M9X1", "map_id": "A0A3Q1M9X1", "name": "TNFRSF18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DT5", "map_id": "Q08DT5", "name": "TNFSF18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076237", "map_id": "none", "name": "TNFSF15 binds TNFRSF25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074274", "map_id": "E1BF06", "name": "TNFSF15", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10076233", "map_id": "A0A3Q1LIC4", "name": "TNFRSF25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000085571", "map_id": "ENSBTAT00000085571", "name": "TNFRSF25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076235", "map_id": "none", "name": "TNFRSF25:TNFSF15", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LIC4", "map_id": "A0A3Q1LIC4", "name": "TNFRSF25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073765", "map_id": "none", "name": "TNFSF11 binds TNFRSF11A, B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073621", "map_id": "none", "name": "RANKL,sRANKL trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10073761", "map_id": "A5D7R1", "name": "TNFRSF11B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000009759", "map_id": "ENSBTAT00000009759", "name": "TNFRSF11B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073763", "map_id": "none", "name": "TNFSF11,sTNFSF11 trimer:3xTNFRSF11B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5D7R1", "map_id": "A5D7R1", "name": "TNFRSF11B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076165", "map_id": "none", "name": "OX40L binds OX40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10076161", "map_id": "none", "name": "OX40L trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BGY4", "map_id": "E1BGY4", "name": "TNFSF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003763", "map_id": "ENSBTAT00000003763", "name": "TNFSF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076155", "map_id": "A0A3Q1M5M3", "name": "TNFRSF4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000066801", "map_id": "ENSBTAT00000066801", "name": "TNFRSF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076163", "map_id": "none", "name": "3xOX40:OX40L trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M5M3", "map_id": "A0A3Q1M5M3", "name": "TNFRSF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074340", "map_id": "none", "name": "sBAFF,sAPRIL binds TACI,BCMA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074326", "map_id": "none", "name": "sBAFF,sAPRIL trimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q3ZBM0", "map_id": "Q3ZBM0", "name": "phospho-TNFSF13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000141", "map_id": "ENSBTAT00000000141", "name": "phospho-TNFSF13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074336", "map_id": "none", "name": "TAC1,BCMA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MU29", "map_id": "F1MU29", "name": "TNFRSF13B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020341", "map_id": "ENSBTAT00000020341", "name": "TNFRSF13B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M673", "map_id": "A0A3Q1M673", "name": "TNFRSF17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085489", "map_id": "ENSBTAT00000085489", "name": "TNFRSF17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074338", "map_id": "none", "name": "sBAFF,sAPRIL:3xTAC1,BCMA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074312", "map_id": "none", "name": "TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073669", "map_id": "none", "name": "3xLTBR:lymphotoxin,TNFSF14 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073585", "map_id": "none", "name": "cIAP1,2:TRAF2:TRAF3:NIK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10073671", "map_id": "none", "name": "3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074314", "map_id": "none", "name": "TRAFs bind RANK:RANKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073623", "map_id": "none", "name": "3xRANK:RANKL,sRANKL trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073625", "map_id": "none", "name": "3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10073757", "map_id": "none", "name": "TWEAK binds FN14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073601", "map_id": "A0A3Q1LHY0", "name": "TNFRSF12A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10073597", "map_id": "none", "name": "sTWEAK,TWEAK homotrimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10073603", "map_id": "none", "name": "3xFN14:sTWEAK,TWEAK homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074316", "map_id": "none", "name": "TRAF3 binds BAFFR:BAFF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073637", "map_id": "none", "name": "3xBAFFR:BAFF trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073639", "map_id": "none", "name": "3xBAFFR:BAFF trimer:TRAF3:NIK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074318", "map_id": "none", "name": "TRAF2:cIAP1/2 complex binds FN14:TWEAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073605", "map_id": "none", "name": "3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074320", "map_id": "none", "name": "sBAFF trimer binds BAFFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073635", "map_id": "none", "name": "sBAFF trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10073629", "map_id": "F1MJD0", "name": "TNFRSF13C", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10074306", "map_id": "none", "name": "RANKL,sRANKL trimer binds RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073609", "map_id": "F1MTC1", "name": "TNFRSF11A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10074304", "map_id": "none", "name": "RANK:RANKL,sRANKL trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074308", "map_id": "none", "name": "2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073667", "map_id": "none", "name": "LTBR:lymphotoxin,TNFSF14 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10073643", "map_id": "A6QQ46", "name": "LTBR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10074310", "map_id": "none", "name": "2xRANK binds RANKL,sRANKL trimer:RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10073699", "map_id": "none", "name": "K63polyUb-cIAP1,2 ubiquitinates TRAF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10073696", "map_id": "none", "name": "TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071948", "map_id": "none", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047524", "map_id": "E1BL08", "name": "MAP3K14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10073708", "map_id": "none", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073705", "map_id": "E1BL08", "name": "phospho-MAP3K14", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071982", "map_id": "none", "name": "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071979", "map_id": "none", "name": "Active NIK:p-S176,180-IKKA dimer:p100:RELB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MBB7", "map_id": "A7MBB7", "name": "NFKB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007904", "map_id": "ENSBTAT00000007904", "name": "NFKB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBB0", "map_id": "F1MBB0", "name": "RELB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055496", "map_id": "ENSBTAT00000055496", "name": "RELB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071971", "map_id": "none", "name": "Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072030", "map_id": "none", "name": "p52:RELB translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071991", "map_id": "none", "name": "p52:RELB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10072028", "map_id": "none", "name": "p52:RELB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071975", "map_id": "none", "name": "SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056243", "map_id": "none", "name": "CUL1:FBXW11:SKP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10071973", "map_id": "none", "name": "Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10057834", "map_id": "none", "name": "PRLR binds SCF beta-TrCP complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054520", "map_id": "none", "name": "PRLR ligands:p-S349-PRLR:JAK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LZG1", "map_id": "A0A3Q1LZG1", "name": "GH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P01239", "map_id": "P01239", "name": "PRL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020313", "map_id": "ENSBTAT00000020313", "name": "PRL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M283", "map_id": "A0A3Q1M283", "name": "PRLR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082398", "map_id": "ENSBTAT00000082398", "name": "PRLR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054522", "map_id": "none", "name": "PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10054524", "map_id": "none", "name": "Prolactin receptor ligands bind the prolactin receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10054501", "map_id": "none", "name": "Prolactin receptor ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10054509", "map_id": "none", "name": "PRLR:JAK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10054511", "map_id": "none", "name": "PRLR ligands:PRLR:JAK2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10060412", "map_id": "none", "name": "PRLR activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10057836", "map_id": "none", "name": "PRLR is phosphorylated at Ser-349", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10057823", "map_id": "none", "name": "PRLR:JAK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054507", "map_id": "none", "name": "PRLR:JAK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10056335", "map_id": "none", "name": "Prolactin receptor is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056333", "map_id": "none", "name": "PRLR ligands:p-S349- PRLR:JAK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "true" }, { "id": "reaction_10054791", "map_id": "none", "name": "JAK2 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054785", "map_id": "none", "name": "PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10054789", "map_id": "none", "name": "PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10054779", "map_id": "none", "name": "Growth hormone forms dimers and oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10054777", "map_id": "none", "name": "Growth hormone oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10056268", "map_id": "none", "name": "PTP1B dephosphorylates GHR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056255", "map_id": "none", "name": "Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10056265", "map_id": "none", "name": "Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090844", "map_id": "none", "name": "FLT3LG dimer:FLT3 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084303", "map_id": "none", "name": "FLT3LG dimer:FLT3 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10036552", "map_id": "none", "name": "Active FLT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090842", "map_id": "none", "name": "FLT3LG dimer:FLT3:FLT3-binding type I TKIs", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10090840", "map_id": "none", "name": "FLT3:FLT3-binding type II TKIs", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092151", "map_id": "none", "name": "Active FLT3 binds to SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037584", "map_id": "A0A3Q1MHG9", "name": "SYK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092149", "map_id": "none", "name": "active FLT3:SYK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092159", "map_id": "none", "name": "FLT3 phosphorylates GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092135", "map_id": "none", "name": "active FLT3:GRB10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10092156", "map_id": "none", "name": "active FLT3:p-Y GRB10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077790", "map_id": "none", "name": "FLT3LG dimer binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036540", "map_id": "none", "name": "FLT3LG dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10077786", "map_id": "F1MRU0", "name": "FLT3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10077788", "map_id": "none", "name": "FLT3LG dimer:FLT3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084305", "map_id": "none", "name": "FLT3LG dimer:FLT3 binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10092040", "map_id": "none", "name": "PTPRJ dephosphorylates active FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092037", "map_id": "none", "name": "p-Y768,Y969 FLT3 dimer:FLT3LG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10080697", "map_id": "A0A3Q1M6K1", "name": "PTPRJ", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000081330", "map_id": "ENSBTAT00000081330", "name": "PTPRJ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092139", "map_id": "none", "name": "Active FLT3 binds to SH2B3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10055924", "map_id": "A0A3Q1MQG1", "name": "SH2B3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000079236", "map_id": "ENSBTAT00000079236", "name": "SH2B3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092112", "map_id": "none", "name": "active FLT3:SH2B3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MQG1", "map_id": "A0A3Q1MQG1", "name": "SH2B3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092173", "map_id": "none", "name": "FLT3 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092110", "map_id": "none", "name": "active FLT3:CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10092170", "map_id": "none", "name": "active FLT3:pY-CBL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092141", "map_id": "none", "name": "Active FLT3 binds to SLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092116", "map_id": "A0A3Q1MHK8", "name": "SLA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081400", "map_id": "ENSBTAT00000081400", "name": "SLA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092118", "map_id": "none", "name": "active FLT3:SLA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MHK8", "map_id": "A0A3Q1MHK8", "name": "SLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092143", "map_id": "none", "name": "Active FLT3 binds to SLA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092122", "map_id": "Q5BIM7", "name": "SLA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026137", "map_id": "ENSBTAT00000026137", "name": "SLA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092124", "map_id": "none", "name": "active FLT3:SLA2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q5BIM7", "map_id": "Q5BIM7", "name": "SLA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092126", "map_id": "none", "name": "Active FLT3 binds to CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10092147", "map_id": "none", "name": "Active FLT3 binds to SOCS6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10087926", "map_id": "E1BKN8", "name": "SOCS6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092145", "map_id": "none", "name": "active FLT3:SOCS6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092195", "map_id": "none", "name": "Internalization of ubiquitinated FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092178", "map_id": "none", "name": "Ub-pY FLT3:FLT3LG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10092193", "map_id": "none", "name": "Ub-pY FLT3:FLT3LG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10092183", "map_id": "none", "name": "Ubiquitination of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092180", "map_id": "none", "name": "FLT3 E3 ubiquitin ligases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092137", "map_id": "none", "name": "Active FLT3 binds to GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10092043", "map_id": "none", "name": "Active FLT3 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040499", "map_id": "A6QLS3", "name": "CDKN1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083560", "map_id": "A6QLS3", "name": "phospho-CDKN1B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10092033", "map_id": "none", "name": "Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10036565", "map_id": "none", "name": "Active FLT3:GRB2:p-Y-GAB2:PIK3R1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10065275", "map_id": "none", "name": "Active FLT3:GRB2:p-Y GAB2:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092133", "map_id": "none", "name": "Active FLT3 binds to GRAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046947", "map_id": "E1BKA6", "name": "GRAP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020161", "map_id": "ENSBTAT00000020161", "name": "GRAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092131", "map_id": "none", "name": "active FLT3:GRAP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BKA6", "map_id": "E1BKA6", "name": "GRAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092165", "map_id": "none", "name": "Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10092161", "map_id": "none", "name": "active FLT3:p-Y GRB10:PIK3R1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10092163", "map_id": "none", "name": "active FLT3:p-Y GRB10:PI3K", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090916", "map_id": "none", "name": "Active FLT3:GRB2 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036554", "map_id": "none", "name": "Active FLT3: GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074033", "map_id": "none", "name": "Active FLT3:GRB2:SOS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090919", "map_id": "none", "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10052217", "map_id": "none", "name": "Phosphorylation of STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052144", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q04790", "map_id": "Q04790", "name": "IFNAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029080", "map_id": "ENSBTAT00000029080", "name": "IFNAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7E8", "map_id": "E1B7E8", "name": "LOC100335490", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053863", "map_id": "ENSBTAT00000053863", "name": "LOC100335490", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDZ1", "map_id": "E1BDZ1", "name": "LOC523244", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030158", "map_id": "ENSBTAT00000030158", "name": "LOC523244", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6A7", "map_id": "F1N6A7", "name": "IFNAC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054467", "map_id": "ENSBTAT00000054467", "name": "IFNAC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MMI8", "map_id": "A0A3Q1MMI8", "name": "IFNAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073168", "map_id": "ENSBTAT00000073168", "name": "IFNAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MYH9", "map_id": "G3MYH9", "name": "LOC618947", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064849", "map_id": "ENSBTAT00000064849", "name": "LOC618947", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPD3", "map_id": "A0A3Q1LPD3", "name": "LOC525550", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066449", "map_id": "ENSBTAT00000066449", "name": "LOC525550", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZ20", "map_id": "A0A3Q1LZ20", "name": "IFNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085216", "map_id": "ENSBTAT00000085216", "name": "IFNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052194", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052347", "map_id": "none", "name": "Translocation of p-STAT1:p-STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10052187", "map_id": "none", "name": "p-STAT1 dimer:KPNA1:KPNB1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q58DC4", "map_id": "Q58DC4", "name": "IRF9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036455", "map_id": "ENSBTAT00000036455", "name": "IRF9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052189", "map_id": "none", "name": "Translocation of ISGF3 complex to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10052169", "map_id": "none", "name": "ISGF3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052181", "map_id": "none", "name": "ISGF3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10055946", "map_id": "none", "name": "Dephosphorylation of STAT1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055943", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10055955", "map_id": "none", "name": "Dephosphorylation of TYK2 by PTP1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052222", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10055948", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10055958", "map_id": "none", "name": "Dephosphorylation of JAK1 by SHP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052206", "map_id": "none", "name": "IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052159", "map_id": "none", "name": "Recruitment of STAT2 to p-IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052140", "map_id": "E1B8Z4", "name": "STAT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10052153", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10052157", "map_id": "none", "name": "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10070719", "map_id": "none", "name": "ABCE1 binds RNASEL, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10070711", "map_id": "none", "name": "RNASEL dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A5H027", "map_id": "A5H027", "name": "RNASEL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044248", "map_id": "ENSBTAT00000044248", "name": "RNASEL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070715", "map_id": "A4IFE6", "name": "ABCE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000048747", "map_id": "ENSBTAT00000048747", "name": "ABCE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070717", "map_id": "none", "name": "ABCE1:RNASEL dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A4IFE6", "map_id": "A4IFE6", "name": "ABCE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052147", "map_id": "none", "name": "Formation of p-STAT1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10052210", "map_id": "none", "name": "Recruitment of IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10052204", "map_id": "none", "name": "IFNA/B:IFNAR2:JAK1:STAT2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10052200", "map_id": "none", "name": "IFNAR1:TYK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10052208", "map_id": "none", "name": "IFNAR1:TYK2:TYK2 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052213", "map_id": "none", "name": "Interaction of IRF9 with p-STAT2:p-STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052167", "map_id": "none", "name": "p-STAT2:p-STAT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10052163", "map_id": "Q58DC4", "name": "IRF9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10052233", "map_id": "none", "name": "Phosphorylation of INFAR1 by TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10091725", "map_id": "none", "name": "IFNAR1:TYK2 binds TYK2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678619", "map_id": "none", "name": "TYK2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10052236", "map_id": "none", "name": "Phosphorylation of STAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10052229", "map_id": "none", "name": "Activation of JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052227", "map_id": "none", "name": "p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052196", "map_id": "none", "name": "Release of p-STAT2:p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10056297", "map_id": "none", "name": "ISGylation of protein phosphatase 1 beta (PP2CB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056278", "map_id": "none", "name": "ISG15:UBCH8:ISG15 E3 ligase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O02741", "map_id": "O02741", "name": "ISG15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019573", "map_id": "ENSBTAT00000019573", "name": "ISG15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DII5", "map_id": "A0A452DII5", "name": "UBE2L6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017267", "map_id": "ENSBTAT00000017267", "name": "UBE2L6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VEA3", "map_id": "A2VEA3", "name": "ARIH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008822", "map_id": "ENSBTAT00000008822", "name": "ARIH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPN8", "map_id": "A0A3Q1LPN8", "name": "HERC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083455", "map_id": "ENSBTAT00000083455", "name": "HERC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056293", "map_id": "O62830", "name": "PPM1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000050064", "map_id": "ENSBTAT00000050064", "name": "PPM1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056295", "map_id": "none", "name": "ISGylated PP2CB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O62830", "map_id": "O62830", "name": "PPM1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056276", "map_id": "none", "name": "ISG15 E3 ligases", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10053116", "map_id": "A0A452DII5", "name": "UBE2L6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056315", "map_id": "none", "name": "ISGylation of host proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056311", "map_id": "none", "name": "ISG15 targets", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MM71", "map_id": "F1MM71", "name": "IFIT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010366", "map_id": "ENSBTAT00000010366", "name": "IFIT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056313", "map_id": "none", "name": "ISGylated host proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056283", "map_id": "none", "name": "ISGylation of IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039246", "map_id": "Q4JF28", "name": "IRF3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000031869", "map_id": "ENSBTAT00000031869", "name": "phospho-IRF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056280", "map_id": "none", "name": "ISGylated IRF3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q4JF28", "map_id": "Q4JF28", "name": "phospho-IRF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060730", "map_id": "none", "name": "Competitive inhibition of translation initiation by ISGylated 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060726", "map_id": "none", "name": "eIF4F:mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MFK0", "map_id": "A0A3Q1MFK0", "name": "EIF4E3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075646", "map_id": "ENSBTAT00000075646", "name": "EIF4E3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8U3", "map_id": "A0A3Q1M8U3", "name": "EIF4G3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086252", "map_id": "ENSBTAT00000086252", "name": "EIF4G3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NL22", "map_id": "Q2NL22", "name": "EIF4A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021327", "map_id": "ENSBTAT00000021327", "name": "EIF4A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ54", "map_id": "Q3SZ54", "name": "EIF4A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000144", "map_id": "ENSBTAT00000000144", "name": "EIF4A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060706", "map_id": "none", "name": "ISGylated 4EHP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LSC2", "map_id": "A0A3Q1LSC2", "name": "EIF4E2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086202", "map_id": "ENSBTAT00000086202", "name": "EIF4E2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MRS1", "map_id": "A0A3Q1MRS1", "name": "EIF4E2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060724", "map_id": "none", "name": "EIF4F", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10060728", "map_id": "none", "name": "ISGylated 4EHP:mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060732", "map_id": "none", "name": "ISGylation of protein translation regulator 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060704", "map_id": "none", "name": "Homologues of EIF4E2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056287", "map_id": "none", "name": "ISGylation of E2 conjugating enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055358", "map_id": "A0A3Q1MAR8", "name": "UBE2E1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056285", "map_id": "none", "name": "ISGylated E2 conjugating enzymes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056289", "map_id": "none", "name": "Interaction of E3 ligase with ISG15:E2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10056270", "map_id": "none", "name": "ISG15:UBCH8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060694", "map_id": "none", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_141681", "map_id": "none", "name": "polypeptide", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060689", "map_id": "A0A3Q1NIT7", "name": "USP18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000086230", "map_id": "ENSBTAT00000086230", "name": "USP18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089341", "map_id": "none", "name": "OASL binds DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053104", "map_id": "F1MKU1", "name": "DDX58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089337", "map_id": "F1MXX7", "name": "OASL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000004270", "map_id": "ENSBTAT00000004270", "name": "OASL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089339", "map_id": "none", "name": "OASL:DDX58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MXX7", "map_id": "F1MXX7", "name": "OASL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089696", "map_id": "none", "name": "RNASEL cleaves cellular ssRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_170292", "map_id": "none", "name": "ssRNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9009945", "map_id": "none", "name": "RNA fragment with 2'-3' cyclic phosphate ", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089693", "map_id": "none", "name": "RNASEL:2'-5' oligoadenylate", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089349", "map_id": "none", "name": "ABCE1 binds RNASEL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089345", "map_id": "A5H027", "name": "RNASEL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089343", "map_id": "A4IFE6", "name": "ABCE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089347", "map_id": "none", "name": "ABCE1:RNASEL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089703", "map_id": "none", "name": "PDE12 cleaves 2'-5' oligoadenylates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8983696", "map_id": "none", "name": "2'-5' oligoadenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10089700", "map_id": "Q08DF7", "name": "PDE12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020675", "map_id": "ENSBTAT00000020675", "name": "PDE12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057588", "map_id": "none", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057585", "map_id": "none", "name": "TREK homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LQ50", "map_id": "A0A3Q1LQ50", "name": "KCNK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074252", "map_id": "ENSBTAT00000074252", "name": "KCNK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGH7", "map_id": "E1BGH7", "name": "KCNK4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011399", "map_id": "ENSBTAT00000011399", "name": "KCNK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLI5", "map_id": "F1MLI5", "name": "KCNK10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025779", "map_id": "ENSBTAT00000025779", "name": "KCNK10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091423", "map_id": "none", "name": "GSDMD (1-275) binds bacterial cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9647661", "map_id": "CHEBI:28494", "name": "cardiolipin", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10037243", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000087110", "map_id": "ENSBTAT00000087110", "name": "GSDMD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091421", "map_id": "none", "name": "GSDMD(1-275):cardiolipin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MD51", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8954419", "map_id": "CHEBI:28494", "name": "cardiolipin", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10092350", "map_id": "none", "name": "ELANE cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091431", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092343", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092345", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092347", "map_id": "G3MWP1", "name": "ELANE", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091409", "map_id": "none", "name": "GSDMD forms ringshaped oligomers ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10081899", "map_id": "none", "name": "GSDMD oligomer:PIPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_1806180", "map_id": "CHEBI:17526", "name": "PI4P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10081901", "map_id": "none", "name": "GSDMD pore complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091407", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081905", "map_id": "none", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10044670", "map_id": "P10103", "name": "HMGB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000024094", "map_id": "ENSBTAT00000024094", "name": "HMGB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081502", "map_id": "P10103", "name": "HMGB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10081903", "map_id": "none", "name": "GSDME oligomer:PIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BFC3", "map_id": "E1BFC3", "name": "GSDME", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080428", "map_id": "ENSBTAT00000080428", "name": "GSDME", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092341", "map_id": "none", "name": "CASP4, CASP5 cleave GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091433", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10092338", "map_id": "none", "name": "activated CASP4, CASP5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O75601", "map_id": "O75601", "name": "CASP13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027820", "map_id": "ENSBTAT00000027820", "name": "CASP13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091415", "map_id": "none", "name": "GSDMD (1-275) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5620974", "map_id": "none", "name": "PI4P,PI(4,5)P2,PIP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10091413", "map_id": "none", "name": "GSDMD (1-275):PIPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091439", "map_id": "none", "name": "CASP1 cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091437", "map_id": "A0A3Q1MD51", "name": "GSDMD", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091425", "map_id": "none", "name": "GSDMD oligomerizes into arc-, slit-shaped structures", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10092352", "map_id": "none", "name": "GSDME oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091427", "map_id": "none", "name": "GSDME (1-270):PIPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037249", "map_id": "E1BFC3", "name": "GSDME", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10092354", "map_id": "none", "name": "GZMB cleaves GSDME", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091417", "map_id": "E1BFC3", "name": "GSDME", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091419", "map_id": "E1BFC3", "name": "GSDME", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091429", "map_id": "none", "name": "GSDME (1-270) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10037253", "map_id": "none", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10037239", "map_id": "P62894", "name": "CYCS", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10037211", "map_id": "P62894", "name": "CYCS", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037235", "map_id": "none", "name": "Active oligomeric BAK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q05KI7", "map_id": "Q05KI7", "name": "BAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000549", "map_id": "ENSBTAT00000000549", "name": "BAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037245", "map_id": "none", "name": "GSDMD(1-275):cardiolipin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10037251", "map_id": "none", "name": "GSDME:cardiolipin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10092356", "map_id": "none", "name": "GSDMD (1-275) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10092358", "map_id": "none", "name": "GSDME (1-270) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10091817", "map_id": "none", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678991", "map_id": "none", "name": "tacrolimus", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091815", "map_id": "none", "name": "FKBP1A:tacrolimus", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056239", "map_id": "none", "name": "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10056236", "map_id": "none", "name": "p-RASGRP1,3:DAG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044568", "map_id": "none", "name": "Caspase-mediated cleavage of Lamin A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044551", "map_id": "F1MYG5", "name": "LMNA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000023373", "map_id": "ENSBTAT00000023373", "name": "LMNA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044555", "map_id": "F1MYG5", "name": "LMNA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10044553", "map_id": "F1MYG5", "name": "LMNA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10044565", "map_id": "none", "name": "active caspase-6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3X702", "map_id": "G3X702", "name": "CASP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016642", "map_id": "ENSBTAT00000016642", "name": "CASP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090575", "map_id": "none", "name": "Caspase-6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10044753", "map_id": "none", "name": "active caspase-6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10044578", "map_id": "none", "name": "Caspase-mediated cleavage of Lamin B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044572", "map_id": "A0A3Q1LNG7", "name": "LMNB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044576", "map_id": "A0A3Q1LNG7", "name": "LMNB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10044574", "map_id": "A0A3Q1LNG7", "name": "LMNB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10036080", "map_id": "none", "name": "Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036074", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBP80:CBP20:SLBP:ZFP100 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MM18", "map_id": "A0A3Q1MM18", "name": "SNRPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086549", "map_id": "ENSBTAT00000086549", "name": "SNRPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LW50", "map_id": "A0A3Q1LW50", "name": "SNRPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076380", "map_id": "ENSBTAT00000076380", "name": "SNRPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHK8", "map_id": "E1BHK8", "name": "SNRPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N150", "map_id": "F1N150", "name": "SNRPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0Z8", "map_id": "Q3T0Z8", "name": "SNRPF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021643", "map_id": "ENSBTAT00000021643", "name": "SNRPF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFN1", "map_id": "A4IFN1", "name": "LSM10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033237", "map_id": "ENSBTAT00000033237", "name": "LSM10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBL0", "map_id": "Q3ZBL0", "name": "SNRPG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007241", "map_id": "ENSBTAT00000007241", "name": "SNRPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKH0", "map_id": "F1MKH0", "name": "LSM11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013683", "map_id": "ENSBTAT00000013683", "name": "LSM11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M973", "map_id": "A0A3Q1M973", "name": "2xMe-SNRPB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001380", "map_id": "ENSBTAT00000001380", "name": "2xMe-SNRPB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N038", "map_id": "F1N038", "name": "ZNF473", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016000", "map_id": "ENSBTAT00000016000", "name": "ZNF473", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0Z1", "map_id": "A0A3Q1N0Z1", "name": "SLBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074628", "map_id": "ENSBTAT00000074628", "name": "SLBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036078", "map_id": "none", "name": "Mature Intronless transcript derived Histone mRNA:SLBP:CBP80:CBP20", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036072", "map_id": "none", "name": "U7 snRNP:ZNF473", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036915", "map_id": "none", "name": "Cleavage of the 3'-end of the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036911", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBC:ZFP100 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036913", "map_id": "none", "name": "Mature intronless transcript derived Histone pre-mRNA:CBC complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10083967", "map_id": "none", "name": "BTNL2 binds activated T cells surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_8851965", "map_id": "none", "name": "Activated T Cell surface", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10083963", "map_id": "A6QNP4", "name": "BTNL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000049415", "map_id": "ENSBTAT00000049415", "name": "BTNL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083965", "map_id": "none", "name": "BTNL2: activated T Cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QNP4", "map_id": "A6QNP4", "name": "BTNL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083959", "map_id": "none", "name": "BTN2A2 binds T cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083955", "map_id": "F1MZI6", "name": "LOC107131749", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000045031", "map_id": "ENSBTAT00000045031", "name": "LOC107131749", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083957", "map_id": "none", "name": "BTN2A2:activated T Cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MZI6", "map_id": "F1MZI6", "name": "LOC107131749", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046811", "map_id": "none", "name": "CD28 homodimer binds B7-1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046779", "map_id": "none", "name": "CD28 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1ND77", "map_id": "A0A3Q1ND77", "name": "phospho-CD28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079588", "map_id": "ENSBTAT00000079588", "name": "phospho-CD28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046793", "map_id": "none", "name": "CD80 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3S5ZP81", "map_id": "A0A3S5ZP81", "name": "CD80", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079899", "map_id": "ENSBTAT00000079899", "name": "CD80", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046809", "map_id": "none", "name": "CD28:B7-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046907", "map_id": "none", "name": "Phosphorylation of CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037459", "map_id": "A0JNB0", "name": "FYN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10046905", "map_id": "none", "name": "CD28:B7-1,B7-2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MLL9", "map_id": "A0A3Q1MLL9", "name": "CD86", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081673", "map_id": "ENSBTAT00000081673", "name": "CD86", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046818", "map_id": "none", "name": "phospho CD28:B7-1/B7-2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043788", "map_id": "none", "name": "Src family tyrosine kinases (SFKs)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047530", "map_id": "none", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047527", "map_id": "E1BL08", "name": "phospho-MAP3K14", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047008", "map_id": "A0A3Q1LK92", "name": "phospho-MAP3K8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000080762", "map_id": "ENSBTAT00000080762", "name": "phospho-MAP3K8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046932", "map_id": "none", "name": "CD28 bound PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046929", "map_id": "none", "name": "CD28:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046787", "map_id": "none", "name": "CD28 homodimer binds B7-2 monomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046783", "map_id": "A0A3Q1MLL9", "name": "CD86", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10046785", "map_id": "none", "name": "CD28:B7-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046943", "map_id": "none", "name": "Activation of Vav1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046936", "map_id": "none", "name": "VAV1:PIP3:CD28:GRB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046940", "map_id": "none", "name": "p-Y142,160,174-VAV1:PIP3:CD28:GRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046822", "map_id": "none", "name": "Grb2 binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046820", "map_id": "none", "name": "CD28:Grb2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046951", "map_id": "none", "name": "Gads binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046949", "map_id": "none", "name": "CD28:GRAP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046834", "map_id": "none", "name": "ICOS binds ICOSL/B7-H2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046830", "map_id": "E1BCU8", "name": "ICOSLG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019810", "map_id": "ENSBTAT00000019810", "name": "ICOSLG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046826", "map_id": "Q58DF9", "name": "ICOS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000028775", "map_id": "ENSBTAT00000028775", "name": "ICOS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046832", "map_id": "none", "name": "ICOS:ICOSL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q58DF9", "map_id": "Q58DF9", "name": "ICOS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCU8", "map_id": "E1BCU8", "name": "ICOSLG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046909", "map_id": "none", "name": "Phosphorylation of CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046805", "map_id": "none", "name": "PP2A:CTLA4:B7-1/B7-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q28090", "map_id": "Q28090", "name": "phospho-CTLA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017527", "map_id": "ENSBTAT00000017527", "name": "phospho-CTLA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046899", "map_id": "none", "name": "p-Y165,Y182-CTLA-4 dimer:SFKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046959", "map_id": "none", "name": "PP2A binds CTLA4 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046801", "map_id": "none", "name": "CTLA-4 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046803", "map_id": "none", "name": "CTLA-4:PP2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046807", "map_id": "none", "name": "CTLA-4 binds B7-1/B7-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046795", "map_id": "none", "name": "B7-1 homodimer/ B7-2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046903", "map_id": "none", "name": "SHP2 phosphatase binds CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046901", "map_id": "none", "name": "pCTLA-4:Src kinases:SHP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10075923", "map_id": "none", "name": "CD22 binds itself to form homo-oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10075919", "map_id": "A0A3Q1NI55", "name": "CD22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000081458", "map_id": "ENSBTAT00000081458", "name": "CD22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075921", "map_id": "none", "name": "NAc-CD22 homo-oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NI55", "map_id": "A0A3Q1NI55", "name": "CD22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065019", "map_id": "none", "name": "Formation of nonameric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane" }, { "id": "species_10065015", "map_id": "none", "name": "alpha beta dimer:Ii trimer:calnexin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MEG8", "map_id": "A0A3Q1MEG8", "name": "CD74", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074178", "map_id": "ENSBTAT00000074178", "name": "CD74", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q30309", "map_id": "Q30309", "name": "BoLA-DRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014072", "map_id": "ENSBTAT00000014072", "name": "BoLA-DRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H6Y1", "map_id": "A6H6Y1", "name": "BOLA-DQA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019939", "map_id": "ENSBTAT00000019939", "name": "BOLA-DQA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQE7", "map_id": "A6QQE7", "name": "BOLA-DYA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003342", "map_id": "ENSBTAT00000003342", "name": "BOLA-DYA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLZ1", "map_id": "E1BLZ1", "name": "BOLA-DQA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034283", "map_id": "ENSBTAT00000034283", "name": "BOLA-DQA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0X9", "map_id": "F1N0X9", "name": "BOLA-DQA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019800", "map_id": "ENSBTAT00000019800", "name": "BOLA-DQA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N610", "map_id": "F1N610", "name": "BLA-DQB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026100", "map_id": "ENSBTAT00000026100", "name": "BLA-DQB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJU5", "map_id": "F1MJU5", "name": "BOLA-DRB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018484", "map_id": "ENSBTAT00000018484", "name": "BOLA-DRB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MI49", "map_id": "A0A3Q1MI49", "name": "HLA class II histocompatibility antigen, DR beta 4 chain", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085256", "map_id": "ENSBTAT00000085256", "name": "HLA class II histocompatibility antigen, DR beta 4 chain", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUX0", "map_id": "A0A3Q1MUX0", "name": "DSB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078884", "map_id": "ENSBTAT00000078884", "name": "DSB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML60", "map_id": "F1ML60", "name": "HLA class II histocompatibility antigen, DR beta 4 chain", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M088", "map_id": "A0A3Q1M088", "name": "BOLA-DRB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075226", "map_id": "ENSBTAT00000075226", "name": "BOLA-DRB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWT2", "map_id": "G3MWT2", "name": "BOLA-DQB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064718", "map_id": "ENSBTAT00000064718", "name": "BOLA-DQB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q70IB5", "map_id": "Q70IB5", "name": "BoLA-DIB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063954", "map_id": "ENSBTAT00000063954", "name": "BoLA-DIB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064164", "map_id": "none", "name": "MHC II alpha beta heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10065017", "map_id": "none", "name": "2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064219", "map_id": "none", "name": "Cleavage of lip22 to lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10063931", "map_id": "none", "name": "MHC II:lip22 nonamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10063937", "map_id": "none", "name": "MHC II:lip10 nonamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10064216", "map_id": "none", "name": "Cathepsin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "P25326", "map_id": "P25326", "name": "CTSS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022774", "map_id": "ENSBTAT00000022774", "name": "CTSS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065051", "map_id": "none", "name": "Loading of antigenic peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10065047", "map_id": "none", "name": "peptide free MHC II:HLA-DM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "F1MHT7", "map_id": "F1MHT7", "name": "BOLA-DOA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008504", "map_id": "ENSBTAT00000008504", "name": "BOLA-DOA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5KTP6", "map_id": "Q5KTP6", "name": "BoLA-DOB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065976", "map_id": "ENSBTAT00000065976", "name": "BoLA-DOB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLV2", "map_id": "F1MLV2", "name": "BOLA-DMA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020881", "map_id": "ENSBTAT00000020881", "name": "BOLA-DMA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DW7", "map_id": "Q58DW7", "name": "HLA-DMB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016520", "map_id": "ENSBTAT00000016520", "name": "HLA-DMB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2213226", "map_id": "none", "name": "MHC class II epitopes", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10065045", "map_id": "none", "name": "HLA-DM/HLA-DO", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10065049", "map_id": "none", "name": "peptide loaded MHC class II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10065021", "map_id": "none", "name": "Fusion of COPII vesicle with Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10064275", "map_id": "none", "name": "Nonameric complex in COPII vesicle", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "species_10064116", "map_id": "none", "name": "Nonameric complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10064225", "map_id": "none", "name": "COPII", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064221", "map_id": "none", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2213225", "map_id": "none", "name": "unfolded antigen", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10063969", "map_id": "none", "name": "Cathepsin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "Q0VCU3", "map_id": "Q0VCU3", "name": "CTSF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014587", "map_id": "ENSBTAT00000014587", "name": "CTSF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065055", "map_id": "none", "name": "Disassociation of CLIP from MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10063941", "map_id": "none", "name": "MHC II:CLIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10065053", "map_id": "A0A3Q1MEG8", "name": "CD74", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10065009", "map_id": "none", "name": "Trafficking of nonameric complex in the endocytic pathway", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane" }, { "id": "species_10065007", "map_id": "none", "name": "Nonameric complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "species_10063925", "map_id": "none", "name": "Nonameric complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10084401", "map_id": "none", "name": "LAG3 (CD233) binds MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10064210", "map_id": "none", "name": "MHC class II alpha/beta dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10084397", "map_id": "A0A3Q1LYZ8", "name": "LAG3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000077596", "map_id": "ENSBTAT00000077596", "name": "LAG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084399", "map_id": "none", "name": "LAG3:MHC II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LYZ8", "map_id": "A0A3Q1LYZ8", "name": "LAG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065011", "map_id": "none", "name": "Formation of MHC II alpha beta heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane" }, { "id": "species_10064162", "map_id": "none", "name": "HLA II beta chain", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10064138", "map_id": "none", "name": "HLA II alpha chain", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064277", "map_id": "none", "name": "Formation of COPII vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10064223", "map_id": "none", "name": "Nonameric complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10064118", "map_id": "none", "name": "Transport of MHC II:Ii complex along Golgi to TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10064020", "map_id": "none", "name": "Nonameric complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10064214", "map_id": "none", "name": "Insertion of MHC II:Ii complex in to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10064066", "map_id": "none", "name": "MHC class II alpha/beta/Ii nonamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10064212", "map_id": "none", "name": "MHC class II alpha/beta/Ii nonamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10064068", "map_id": "none", "name": "Transport of MHC II:Ii complex to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane" }, { "id": "reaction_10063972", "map_id": "none", "name": "Generation of CLIP from lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10042635", "map_id": "none", "name": "CD200 binds to CD200R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042631", "map_id": "Q3ZC60", "name": "CD200", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000027169", "map_id": "ENSBTAT00000027169", "name": "CD200", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042627", "map_id": "A5D7V5", "name": "CD200R1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001635", "map_id": "ENSBTAT00000001635", "name": "CD200R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042633", "map_id": "none", "name": "CD200 bound to CD200R", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5D7V5", "map_id": "A5D7V5", "name": "CD200R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC60", "map_id": "Q3ZC60", "name": "CD200", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042253", "map_id": "none", "name": "MADCAM1-1 binds Integrin alpha4beta7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042245", "map_id": "none", "name": "Integrin alpha4beta7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MEF6", "map_id": "F1MEF6", "name": "ITGA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012194", "map_id": "ENSBTAT00000012194", "name": "ITGA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RKH9", "map_id": "F6RKH9", "name": "ITGB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025279", "map_id": "ENSBTAT00000025279", "name": "ITGB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042249", "map_id": "A0A3Q1MBF2", "name": "MADCAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068738", "map_id": "ENSBTAT00000068738", "name": "MADCAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042251", "map_id": "none", "name": "Integrin alpha4beta7:MADCAM1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MBF2", "map_id": "A0A3Q1MBF2", "name": "MADCAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042623", "map_id": "none", "name": "CRTAM binds to NECL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042615", "map_id": "A7YWT5", "name": "CRTAM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000076490", "map_id": "ENSBTAT00000076490", "name": "CRTAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042619", "map_id": "A0A3Q1M4X8", "name": "PVR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000083396", "map_id": "ENSBTAT00000083396", "name": "PVR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042621", "map_id": "none", "name": "CRTAM bound to NECL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M4X8", "map_id": "A0A3Q1M4X8", "name": "PVR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWT5", "map_id": "A7YWT5", "name": "CRTAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042129", "map_id": "none", "name": "TCR complex interacts with peptide antigen-presenting MHC Class I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042125", "map_id": "none", "name": "T-cell receptor complex with CD8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MC47", "map_id": "F1MC47", "name": "TRAC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046313", "map_id": "ENSBTAT00000046313", "name": "TRAC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3D2", "map_id": "A0A3Q1M3D2", "name": "TCRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000064618", "map_id": "ENSBTAP00000064618", "name": "TCRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBP3", "map_id": "F1MBP3", "name": "T-cell receptor alpha chain V region PY14 precursor", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050022", "map_id": "ENSBTAT00000050022", "name": "T-cell receptor alpha chain V region PY14 precursor", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT21", "map_id": "A0A3Q1MT21", "name": "TRAV19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067721", "map_id": "ENSBTAT00000067721", "name": "TRAV19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJB8", "map_id": "F1MJB8", "name": "LOC100300510", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054092", "map_id": "ENSBTAT00000054092", "name": "LOC100300510", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLJ5", "map_id": "E1BLJ5", "name": "TCRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055909", "map_id": "ENSBTAT00000055909", "name": "TCRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MYX4", "map_id": "A0A3Q1MYX4", "name": "TRBV12-3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085379", "map_id": "ENSBTAT00000085379", "name": "TRBV12-3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCU4", "map_id": "Q0VCU4", "name": "CD247", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016878", "map_id": "ENSBTAT00000016878", "name": "CD247", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q28072", "map_id": "Q28072", "name": "CD3D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008462", "map_id": "ENSBTAT00000008462", "name": "CD3D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MAZ7", "map_id": "A7MAZ7", "name": "CD8A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028175", "map_id": "ENSBTAT00000028175", "name": "CD8A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YW30", "map_id": "A7YW30", "name": "CD8B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033046", "map_id": "ENSBTAT00000033046", "name": "CD8B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042127", "map_id": "none", "name": "TCR interacting with antigen-bearing MHC Class I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074993", "map_id": "none", "name": "Sialic acid binds SIGLEC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1006168", "map_id": "CHEBI:28879", "name": "Sialic acid", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10074989", "map_id": "none", "name": "SIGLEC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MHX4", "map_id": "A0A3Q1MHX4", "name": "SIGLEC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081728", "map_id": "ENSBTAT00000081728", "name": "SIGLEC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZR7", "map_id": "G3MZR7", "name": "LOC618268", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064604", "map_id": "ENSBTAT00000064604", "name": "LOC618268", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8E5", "map_id": "E1B8E5", "name": "LOC100138951", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052760", "map_id": "ENSBTAT00000052760", "name": "LOC100138951", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKZ8", "map_id": "E1BKZ8", "name": "SIGLEC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011656", "map_id": "ENSBTAT00000011656", "name": "SIGLEC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MST2", "map_id": "F1MST2", "name": "LOC618463", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031802", "map_id": "ENSBTAT00000031802", "name": "LOC618463", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074991", "map_id": "none", "name": "SIGLEC:sialic acid", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10075009", "map_id": "none", "name": "CLEC2B binds KLRF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074999", "map_id": "none", "name": "KLRF1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5PJG8", "map_id": "A5PJG8", "name": "KLRF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042955", "map_id": "ENSBTAT00000042955", "name": "KLRF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075005", "map_id": "none", "name": "CLEC2B dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NBN7", "map_id": "A0A3Q1NBN7", "name": "CLEC2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082969", "map_id": "ENSBTAT00000082969", "name": "CLEC2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075007", "map_id": "none", "name": "KLRF1 dimer:CLEC2B dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084672", "map_id": "none", "name": "PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084640", "map_id": "F1MJX3", "name": "PILRA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001412", "map_id": "ENSBTAT00000001412", "name": "PILRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084668", "map_id": "none", "name": "PIANP,NPDC1,CLEC4G,COLEC12 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B7F4", "map_id": "E1B7F4", "name": "CLEC4G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017867", "map_id": "ENSBTAT00000017867", "name": "CLEC4G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H6Y6", "map_id": "A6H6Y6", "name": "NPDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065575", "map_id": "ENSBTAT00000065575", "name": "NPDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084670", "map_id": "none", "name": "PILRA:PIANP,NPDC1,CLEC4G,COLEC12 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MJX3", "map_id": "F1MJX3", "name": "PILRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074899", "map_id": "none", "name": "SAP and EAT2 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074895", "map_id": "none", "name": "SLAMF6 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MLN1", "map_id": "F1MLN1", "name": "SLAMF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034482", "map_id": "ENSBTAT00000034482", "name": "SLAMF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074889", "map_id": "none", "name": "SAP,EAT2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZBB1", "map_id": "Q3ZBB1", "name": "SH2D1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036966", "map_id": "ENSBTAT00000036966", "name": "SH2D1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4F1", "map_id": "A0A3Q1M4F1", "name": "SH2D1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085516", "map_id": "ENSBTAT00000085516", "name": "SH2D1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074897", "map_id": "none", "name": "SLAMF6:SLAMF6:SAP,EAT2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10076963", "map_id": "none", "name": "TREM,CD300 binds lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5696348", "map_id": "none", "name": "CERA,PE,PS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_1500646", "map_id": "CHEBI:18303", "name": "PS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10076959", "map_id": "none", "name": "TREM, CD300", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MNL2", "map_id": "F1MNL2", "name": "TREML2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020853", "map_id": "ENSBTAT00000020853", "name": "TREML2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BI56", "map_id": "E1BI56", "name": "TREML1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008500", "map_id": "ENSBTAT00000008500", "name": "TREML1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGI2", "map_id": "F1MGI2", "name": "LOC509881", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010642", "map_id": "ENSBTAT00000010642", "name": "LOC509881", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFU3", "map_id": "E1BFU3", "name": "LOC526163", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040027", "map_id": "ENSBTAT00000040027", "name": "LOC526163", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ML46", "map_id": "A0A3Q1ML46", "name": "CD300A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071567", "map_id": "ENSBTAT00000071567", "name": "CD300A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LX01", "map_id": "A0A3Q1LX01", "name": "CD300E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070885", "map_id": "ENSBTAT00000070885", "name": "CD300E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MG16", "map_id": "F1MG16", "name": "CD300LF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003593", "map_id": "ENSBTAT00000003593", "name": "CD300LF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT87", "map_id": "A0A3Q1MT87", "name": "CD300LB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077738", "map_id": "ENSBTAT00000077738", "name": "CD300LB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076961", "map_id": "none", "name": "TRIM, CD300:lipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10042786", "map_id": "none", "name": "KIR2DL4 interacting with HLA-G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10042782", "map_id": "none", "name": "HLA-G", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10042780", "map_id": "none", "name": "Homologues of KIR2DL4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G5E5W5", "map_id": "G5E5W5", "name": "KIR2DL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011326", "map_id": "ENSBTAT00000011326", "name": "KIR2DL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8SPQ5", "map_id": "Q8SPQ5", "name": "KIR2DL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080712", "map_id": "ENSBTAT00000080712", "name": "KIR2DL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ME80", "map_id": "A0A3Q1ME80", "name": "KIR3DL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077038", "map_id": "ENSBTAT00000077038", "name": "KIR3DL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQ30", "map_id": "A0A3Q1MQ30", "name": "KIR3DL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081128", "map_id": "ENSBTAT00000081128", "name": "KIR3DL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQD8", "map_id": "F1MQD8", "name": "KIR2DS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053352", "map_id": "ENSBTAT00000053352", "name": "KIR2DS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X797", "map_id": "G3X797", "name": "KIR3DS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022538", "map_id": "ENSBTAT00000022538", "name": "KIR3DS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5B4", "map_id": "G5E5B4", "name": "KIR2DL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5G6", "map_id": "G5E5G6", "name": "LOC100852061", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018094", "map_id": "ENSBTAT00000018094", "name": "LOC100852061", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10042784", "map_id": "none", "name": "HLA-G interacting with KIR2DL4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084658", "map_id": "none", "name": "PILRA,PILRB bind CD99", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084654", "map_id": "A0A3Q1NN33", "name": "CD99", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000087222", "map_id": "ENSBTAT00000087222", "name": "CD99", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084650", "map_id": "none", "name": "PILRA,PILRB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MN37", "map_id": "A0A3Q1MN37", "name": "PILRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072757", "map_id": "ENSBTAT00000072757", "name": "PILRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084656", "map_id": "none", "name": "PILRA,PILRB:CD99", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NN33", "map_id": "A0A3Q1NN33", "name": "CD99", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074901", "map_id": "none", "name": "SLAMF6 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074893", "map_id": "F1MLN1", "name": "SLAMF6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10043241", "map_id": "none", "name": "Translocation of PLC-gamma1 to PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043234", "map_id": "F1MYF9", "name": "phospho-PLCG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043239", "map_id": "none", "name": "Activated PLC gamma1 bound to PIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043262", "map_id": "none", "name": "PLC-gamma1 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043259", "map_id": "none", "name": "p-PLCG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MMD9", "map_id": "A0A3Q1MMD9", "name": "PLCG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074574", "map_id": "ENSBTAT00000074574", "name": "PLCG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043193", "map_id": "none", "name": "Recruitment of PI3K to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043189", "map_id": "A0A3Q1MCW9", "name": "phospho-TRAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000074583", "map_id": "ENSBTAT00000074583", "name": "phospho-TRAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043191", "map_id": "none", "name": "PI3K bound to TRAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MCW9", "map_id": "A0A3Q1MCW9", "name": "phospho-TRAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043225", "map_id": "none", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043006", "map_id": "E1BMG4", "name": "PRKCQ", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043223", "map_id": "none", "name": "PKC-theta (open): DAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043219", "map_id": "none", "name": "Hydrolysis of PIP3 to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202247", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10043216", "map_id": "A0A3Q1LJT8", "name": "INPP5D", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10043252", "map_id": "none", "name": "Translocation of CARMA1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043248", "map_id": "A0A3S5ZPB2", "name": "CARD11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081933", "map_id": "ENSBTAT00000081933", "name": "CARD11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043180", "map_id": "none", "name": "PDK1:PIP2,PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_1806238", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_10043250", "map_id": "none", "name": "CARMA1 bound to PDK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3S5ZPB2", "map_id": "A0A3S5ZPB2", "name": "CARD11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043304", "map_id": "none", "name": "Oligomerization of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043279", "map_id": "Q17QJ6", "name": "phospho-BCL10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043295", "map_id": "none", "name": "Phosphorylated Bcl10 bound to CARMA1 and RIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043281", "map_id": "none", "name": "Bcl10 trimer bound to CARMA1 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043274", "map_id": "none", "name": "Oligomerization of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043267", "map_id": "none", "name": "Activated CARMA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043265", "map_id": "A0A3S5ZPB2", "name": "phospho-CARD11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043272", "map_id": "none", "name": "CARMA1 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043244", "map_id": "none", "name": "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10043212", "map_id": "none", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043202", "map_id": "none", "name": "p-Y90-PKC-theta:DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043209", "map_id": "none", "name": "Active PKC theta bound to DAG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043182", "map_id": "none", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202277", "map_id": "none", "name": "PIP3, PI(3,4)P2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043298", "map_id": "none", "name": "Phosphorylation of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043293", "map_id": "none", "name": "Bcl10 bound to CARMA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10041331", "map_id": "Q3SZJ2", "name": "RIPK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000020312", "map_id": "ENSBTAT00000020312", "name": "RIPK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043300", "map_id": "none", "name": "Interaction of Bcl10 to CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10043270", "map_id": "none", "name": "Phosphorylation of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10043302", "map_id": "none", "name": "Translocation of TRAF6 to CBM complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043287", "map_id": "none", "name": "MALT1 trimer bound to Bcl10 and CARMA1 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043289", "map_id": "none", "name": "TRAF6 trimer bound to CBM complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10055448", "map_id": "none", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055446", "map_id": "none", "name": "E3:K48-polyubiquitinated substrate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LK96", "map_id": "A0A3Q1LK96", "name": "TRIM36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068172", "map_id": "ENSBTAT00000068172", "name": "TRIM36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M231", "map_id": "A0A3Q1M231", "name": "NEDD4L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070128", "map_id": "ENSBTAT00000070128", "name": "NEDD4L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV49", "map_id": "A0A3Q1LV49", "name": "LOC509283", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082004", "map_id": "ENSBTAT00000082004", "name": "LOC509283", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMK0", "map_id": "Q1RMK0", "name": "RNF115", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010691", "map_id": "ENSBTAT00000010691", "name": "RNF115", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7A0", "map_id": "F1N7A0", "name": "HECTD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015476", "map_id": "ENSBTAT00000015476", "name": "HECTD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M5FKI3", "map_id": "M5FKI3", "name": "UNKL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070499", "map_id": "ENSBTAT00000070499", "name": "UNKL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q4U5R4", "map_id": "Q4U5R4", "name": "RNF114", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039156", "map_id": "ENSBTAT00000039156", "name": "RNF114", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7YRV4", "map_id": "Q7YRV4", "name": "TRIM21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018459", "map_id": "ENSBTAT00000018459", "name": "TRIM21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEX6", "map_id": "F1MEX6", "name": "RNF19B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010969", "map_id": "ENSBTAT00000010969", "name": "RNF19B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBI7", "map_id": "E1BBI7", "name": "RLIM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081934", "map_id": "ENSBTAT00000081934", "name": "RLIM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUP8", "map_id": "A0A3Q1MUP8", "name": "LOC112445131", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079583", "map_id": "ENSBTAT00000079583", "name": "LOC112445131", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0S2", "map_id": "F1N0S2", "name": "LOC101906182", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000291", "map_id": "ENSBTAT00000000291", "name": "LOC101906182", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7V0", "map_id": "G3X7V0", "name": "LOC101907097", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009741", "map_id": "ENSBTAT00000009741", "name": "LOC101907097", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7C1", "map_id": "F1N7C1", "name": "HERC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027362", "map_id": "ENSBTAT00000027362", "name": "HERC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5X8", "map_id": "F1N5X8", "name": "RNF217", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048180", "map_id": "ENSBTAT00000048180", "name": "RNF217", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B964", "map_id": "E1B964", "name": "LONRF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012816", "map_id": "ENSBTAT00000012816", "name": "LONRF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQD1", "map_id": "A6QQD1", "name": "MYLIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005377", "map_id": "ENSBTAT00000005377", "name": "MYLIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCZ2", "map_id": "E1BCZ2", "name": "RBBP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012423", "map_id": "ENSBTAT00000012423", "name": "RBBP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_983123", "map_id": "none", "name": "K48polyUb-antigenic substrate", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055330", "map_id": "none", "name": "E3 ligases in proteasomal degradation", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055451", "map_id": "none", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055428", "map_id": "none", "name": "E3:Ub:substrate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10055422", "map_id": "none", "name": "Ubiquitin:E2 conjugating enzymes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N1X1", "map_id": "A0A3Q1N1X1", "name": "UBE2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076465", "map_id": "ENSBTAT00000076465", "name": "UBE2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055420", "map_id": "none", "name": "E2 Ubiquitin-conjugating enzyme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055453", "map_id": "none", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983035", "map_id": "none", "name": "antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055424", "map_id": "none", "name": "Ag-substrate:E3:E2:Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055491", "map_id": "none", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983036", "map_id": "CHEBI:25676", "name": "precursor peptide fragment (>16 aa)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8942986", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055488", "map_id": "none", "name": "IFN gamma stimulated aminopeptidases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BP91", "map_id": "E1BP91", "name": "NPEPPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015199", "map_id": "ENSBTAT00000015199", "name": "NPEPPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BL29", "map_id": "E1BL29", "name": "BLMH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028490", "map_id": "ENSBTAT00000028490", "name": "BLMH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055431", "map_id": "none", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061657", "map_id": "none", "name": "Beta-defensins 4A and 103 bind CCR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061653", "map_id": "none", "name": "Beta defensins 4A,103", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q50JB9", "map_id": "Q50JB9", "name": "defb300", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072863", "map_id": "ENSBTAT00000072863", "name": "defb300", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5W5I5", "map_id": "Q5W5I5", "name": "defb402", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069740", "map_id": "ENSBTAT00000069740", "name": "defb402", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O02775", "map_id": "O02775", "name": "EBD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009756", "map_id": "ENSBTAT00000009756", "name": "EBD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25068", "map_id": "P25068", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074783", "map_id": "ENSBTAT00000074783", "name": "DEFB4A(?-64)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46165", "map_id": "P46165", "name": "DEFB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018930", "map_id": "ENSBTAT00000018930", "name": "DEFB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q28880", "map_id": "Q28880", "name": "LAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050266", "map_id": "ENSBTAT00000050266", "name": "LAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGE0", "map_id": "F1MGE0", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWU3", "map_id": "G3MWU3", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWY5", "map_id": "G3MWY5", "name": "DEFB10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064773", "map_id": "ENSBTAT00000064773", "name": "DEFB10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXI5", "map_id": "G3MXI5", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0J5", "map_id": "A0A3Q1M0J5", "name": "LOC107131528", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086067", "map_id": "ENSBTAT00000086067", "name": "LOC107131528", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ME63", "map_id": "A0A3Q1ME63", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIQ0", "map_id": "A0A452DIQ0", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHH4", "map_id": "E1BHH4", "name": "DEFB4A(?-64)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045084", "map_id": "A0A3S5ZP45", "name": "CCR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10061655", "map_id": "none", "name": "Beta defensins 4A,103:CCR2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058456", "map_id": "none", "name": "Beta-defensins bind microbial membranes causing disruption", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058452", "map_id": "none", "name": "Beta-defensins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_1462049", "map_id": "CHEBI:62643", "name": "Anionic phospholipids", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10058454", "map_id": "none", "name": "Beta-defensins:anionic phospholipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058492", "map_id": "none", "name": "Beta-defensins 1, 4A and 103 bind CCR6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058488", "map_id": "none", "name": "Beta defensins 1,4A,103", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LWB5", "map_id": "A0A3Q1LWB5", "name": "DEFB1(?-68)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078433", "map_id": "ENSBTAT00000078433", "name": "DEFB1(?-68)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5C9", "map_id": "A0A3Q1M5C9", "name": "DEFB1(?-68)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT20", "map_id": "A0A3Q1MT20", "name": "DEFB1(?-68)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10058490", "map_id": "none", "name": "Beta-defensins 1,4A,103:CCR6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10058486", "map_id": "none", "name": "Beta-defensins are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10058484", "map_id": "none", "name": "Beta-defensins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063801", "map_id": "none", "name": "IDUA hydrolyses Heparan sulfate chain(6)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2090055", "map_id": "CHEBI:63809", "name": "Heparan sulfate chain(6)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2090070", "map_id": "CHEBI:63810", "name": "Heparan sulfate chain(7)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1678617", "map_id": "CHEBI:28481", "name": "aldehydo-L-iduronic acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060675", "map_id": "A0A3Q1NAQ3", "name": "IDUA", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000075910", "map_id": "ENSBTAT00000075910", "name": "IDUA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063803", "map_id": "none", "name": "NAGLU hydrolyses heparan chain(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2090053", "map_id": "CHEBI:63645", "name": "Heparan chain(2)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2065212", "map_id": "CHEBI:63505", "name": "CS/HS precursor", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060682", "map_id": "A0A3Q1LN81", "name": "NAGLU", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000071251", "map_id": "ENSBTAT00000071251", "name": "NAGLU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060634", "map_id": "none", "name": "HGSNAT oligomer acetylates Heparan sulfate chain(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_2090040", "map_id": "CHEBI:63806", "name": "Heparan sulfate chain(3)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_76183", "map_id": "CHEBI:15351", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2090069", "map_id": "CHEBI:63807", "name": "Heparan sulfate chain(4)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060631", "map_id": "none", "name": "HGSNAT oligomer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "A0A3Q1MIE9", "map_id": "A0A3Q1MIE9", "name": "HGSNAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079230", "map_id": "ENSBTAT00000079230", "name": "HGSNAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060685", "map_id": "none", "name": "NAGLU hydrolyses Heparan sulfate chain(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2090080", "map_id": "CHEBI:63808", "name": "Heparan sulfate chain(5)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10063805", "map_id": "none", "name": "HGSNAT oligomer acetylates Heparan chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_2090045", "map_id": "CHEBI:63811", "name": "Heparan chain(1)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10060671", "map_id": "none", "name": "Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060650", "map_id": "none", "name": "HS/HPIN-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_2090023", "map_id": "CHEBI:63666", "name": "Heparan sulfate chain", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10060664", "map_id": "none", "name": "HS core proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10060668", "map_id": "A0A3Q1LRF3", "name": "HPSE2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000085333", "map_id": "ENSBTAT00000085333", "name": "HPSE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063022", "map_id": "none", "name": "HS-GAGs translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060394", "map_id": "none", "name": "HS/HPIN-PGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10060625", "map_id": "none", "name": "IDS hydrolyses Heparan sulfate chain(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10060622", "map_id": "none", "name": "IDS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "F1N2D5", "map_id": "F1N2D5", "name": "IDS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014683", "map_id": "ENSBTAT00000014683", "name": "IDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060741", "map_id": "none", "name": "GUSB tetramer hydrolyses CS/HS precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1678868", "map_id": "CHEBI:4178", "name": "GlcA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2090075", "map_id": "CHEBI:63503", "name": "linker chain(2)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060738", "map_id": "none", "name": "GUSB tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "A3KMY8", "map_id": "A3KMY8", "name": "GUSB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000941", "map_id": "ENSBTAT00000000941", "name": "GUSB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_427963", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10060678", "map_id": "none", "name": "IDUA hydrolyses Heparan sulfate chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2090033", "map_id": "CHEBI:63666", "name": "Heparan sulfate chain(1)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2090072", "map_id": "CHEBI:63805", "name": "Heparan sulfate chain(2)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10072894", "map_id": "none", "name": "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_5653871", "map_id": "CHEBI:17716", "name": "Lac", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10072891", "map_id": "none", "name": "B4GALT1:LALBA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1LYQ2", "map_id": "A0A3Q1LYQ2", "name": "LALBA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066421", "map_id": "ENSBTAT00000066421", "name": "LALBA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072898", "map_id": "none", "name": "B4GALT1 binds LALBA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10072896", "map_id": "A0A3Q1LYQ2", "name": "LALBA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054442", "map_id": "P08037", "name": "B4GALT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_5653875", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10033611", "map_id": "none", "name": "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29578", "map_id": "CHEBI:59776", "name": "GA3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29800", "map_id": "CHEBI:57604", "name": "1,3BPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033608", "map_id": "none", "name": "GAPDH tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P10096", "map_id": "P10096", "name": "GAPDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037753", "map_id": "ENSBTAT00000037753", "name": "GAPDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJE5", "map_id": "Q2KJE5", "name": "GAPDHS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021166", "map_id": "ENSBTAT00000021166", "name": "GAPDHS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080765", "map_id": "none", "name": "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10080762", "map_id": "none", "name": "GNPDA2 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIC9", "map_id": "A0A452DIC9", "name": "GNPDA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000357", "map_id": "ENSBTAT00000000357", "name": "GNPDA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033629", "map_id": "none", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30014", "map_id": "CHEBI:32966", "name": "F1,6PP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033626", "map_id": "none", "name": "phosphofructokinase, L4 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A1A4J1", "map_id": "A1A4J1", "name": "PFKL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056305", "map_id": "ENSBTAT00000056305", "name": "PFKL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30533", "map_id": "CHEBI:28602", "name": "D-Fructose 2,6-bisphosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76190", "map_id": "CHEBI:30769", "name": "CIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10034157", "map_id": "none", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034154", "map_id": "none", "name": "pyruvate kinase tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1JPG7", "map_id": "Q1JPG7", "name": "PKLR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086042", "map_id": "ENSBTAT00000086042", "name": "PKLR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D984", "map_id": "A5D984", "name": "PKM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047412", "map_id": "ENSBTAT00000047412", "name": "PKM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034140", "map_id": "none", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29728", "map_id": "CHEBI:58272", "name": "3PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30485", "map_id": "CHEBI:58289", "name": "2PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034049", "map_id": "none", "name": "phosphoglycerate mutase 1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SZ62", "map_id": "Q3SZ62", "name": "PGAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032937", "map_id": "ENSBTAT00000032937", "name": "PGAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076815", "map_id": "none", "name": "ADPGK:Mg2+ phosphorylates Glc to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_70113", "map_id": "CHEBI:17925", "name": "Glc", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30537", "map_id": "CHEBI:58225", "name": "G6P", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076812", "map_id": "none", "name": "ADPGK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A2VE47", "map_id": "A2VE47", "name": "ADPGK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002065", "map_id": "ENSBTAT00000002065", "name": "ADPGK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088737", "map_id": "none", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955759", "map_id": "CHEBI:18148", "name": "G1,6BP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033547", "map_id": "none", "name": "PGM2L1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A5PKH8", "map_id": "A5PKH8", "name": "PGM2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001019", "map_id": "ENSBTAT00000001019", "name": "PGM2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033620", "map_id": "none", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75970", "map_id": "CHEBI:57642", "name": "DHAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033617", "map_id": "none", "name": "TPI1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIX3", "map_id": "A0A452DIX3", "name": "TPI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026358", "map_id": "ENSBTAT00000026358", "name": "TPI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034071", "map_id": "none", "name": "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034066", "map_id": "none", "name": "aldolase tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3S5ZPB0", "map_id": "A0A3S5ZPB0", "name": "ALDOC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017416", "map_id": "ENSBTAT00000017416", "name": "ALDOC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078710", "map_id": "none", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6798337", "map_id": "CHEBI:19324", "name": "2,3BPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10078707", "map_id": "none", "name": "BPGM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MX69", "map_id": "F1MX69", "name": "BPGM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070308", "map_id": "ENSBTAT00000070308", "name": "BPGM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045050", "map_id": "none", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_198498", "map_id": "CHEBI:30797", "name": "MAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10045047", "map_id": "F1MBS4", "name": "SLC25A10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000000538", "map_id": "ENSBTAT00000000538", "name": "SLC25A10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033757", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10041885", "map_id": "none", "name": "Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113551", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_113782", "map_id": "CHEBI:58225", "name": "G6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10041882", "map_id": "A0A3Q1LIP1", "name": "SLC37A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000077820", "map_id": "ENSBTAT00000077820", "name": "SLC37A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045692", "map_id": "none", "name": "Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041875", "map_id": "none", "name": "SLC25A11 homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P22292", "map_id": "P22292", "name": "SLC25A11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079666", "map_id": "ENSBTAT00000079666", "name": "SLC25A11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034238", "map_id": "none", "name": "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_113780", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10034235", "map_id": "Q29RU6", "name": "G6PC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000013436", "map_id": "ENSBTAT00000013436", "name": "G6PC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045043", "map_id": "none", "name": "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113573", "map_id": "CHEBI:15996", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_372364", "map_id": "CHEBI:58702", "name": "PEP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113525", "map_id": "CHEBI:17552", "name": "GDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10045040", "map_id": "F1MDS3", "name": "PCK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000015834", "map_id": "ENSBTAT00000015834", "name": "PCK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041878", "map_id": "none", "name": "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10033718", "map_id": "none", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76213", "map_id": "CHEBI:30744", "name": "OA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033713", "map_id": "none", "name": "PXLP-K259-GOT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P33097", "map_id": "P33097", "name": "GOT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015873", "map_id": "ENSBTAT00000015873", "name": "GOT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067254", "map_id": "none", "name": "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10067251", "map_id": "F1MSR0", "name": "G6PC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000005552", "map_id": "ENSBTAT00000005552", "name": "G6PC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067240", "map_id": "none", "name": "SLC37A1, SLC37A2 exchange G6P for Pi across the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067237", "map_id": "A0A3Q1M1A8", "name": "SLC37A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000069229", "map_id": "ENSBTAT00000069229", "name": "SLC37A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067247", "map_id": "none", "name": "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10067244", "map_id": "Q148G2", "name": "G6PC3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000021621", "map_id": "ENSBTAT00000021621", "name": "G6PC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045029", "map_id": "none", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10045026", "map_id": "none", "name": "SLC25A12,13", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "A0A3Q1M9V5", "map_id": "A0A3Q1M9V5", "name": "SLC25A12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083179", "map_id": "ENSBTAT00000083179", "name": "SLC25A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LHX4", "map_id": "A0A3Q1LHX4", "name": "SLC25A13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073854", "map_id": "ENSBTAT00000073854", "name": "SLC25A13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033638", "map_id": "none", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033635", "map_id": "none", "name": "FBP1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SZB7", "map_id": "Q3SZB7", "name": "FBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012835", "map_id": "ENSBTAT00000012835", "name": "FBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033561", "map_id": "none", "name": "KHK dimer phosphorylates Fru to Fru 1-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29532", "map_id": "CHEBI:15824", "name": "Fru", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31221", "map_id": "CHEBI:18105", "name": "Fru 1-P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033558", "map_id": "none", "name": "KHK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0II75", "map_id": "Q0II75", "name": "KHK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015052", "map_id": "ENSBTAT00000015052", "name": "KHK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083115", "map_id": "none", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30393", "map_id": "CHEBI:17378", "name": "GA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6799497", "map_id": "CHEBI:32398", "name": "DGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034172", "map_id": "none", "name": "ALDH1A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10033570", "map_id": "none", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033567", "map_id": "none", "name": "TKFC:2Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MGZ4", "map_id": "A0A3Q1MGZ4", "name": "TKFC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085239", "map_id": "ENSBTAT00000085239", "name": "TKFC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072825", "map_id": "none", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5652213", "map_id": "CHEBI:17924", "name": "D-sorbitol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10063530", "map_id": "none", "name": "The keratan chain can be capped by N-acetylneuraminic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063528", "map_id": "none", "name": "Keratan(3)-PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063493", "map_id": "none", "name": "Keratan(4)-PG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063485", "map_id": "none", "name": "KSPG is secreted from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10063470", "map_id": "none", "name": "KSPG(2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063532", "map_id": "none", "name": "B4GALTs transfer Gal to a branch of keratan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063518", "map_id": "none", "name": "Keratan(2)-PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063249", "map_id": "none", "name": "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063230", "map_id": "none", "name": "Gal-glycan-protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063240", "map_id": "none", "name": "Keratan(1)-PG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063246", "map_id": "none", "name": "B3GNT1,2,3,4,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q5EA01", "map_id": "Q5EA01", "name": "B4GAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030023", "map_id": "ENSBTAT00000030023", "name": "B4GAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063232", "map_id": "none", "name": "B4GALTs transfer Gal to the N-glycan precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063222", "map_id": "none", "name": "N-glycan-protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10063520", "map_id": "none", "name": "B4GALTs transfer Gal to the keratan chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10063477", "map_id": "none", "name": "Further sulfation on galactose residues produces KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063464", "map_id": "none", "name": "KSPG(1)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10063474", "map_id": "A4IFE8", "name": "CHST1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000004844", "map_id": "ENSBTAT00000004844", "name": "CHST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063508", "map_id": "none", "name": "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10063505", "map_id": "none", "name": "CHST2,5,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BMN6", "map_id": "E1BMN6", "name": "CHST2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015389", "map_id": "ENSBTAT00000015389", "name": "CHST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK55", "map_id": "E1BK55", "name": "CHST6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056191", "map_id": "ENSBTAT00000056191", "name": "CHST6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060825", "map_id": "none", "name": "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2065213", "map_id": "CHEBI:63517", "name": "ChEBI:63517 chain", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2065269", "map_id": "CHEBI:63516", "name": "ChEBI:63516 chain", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10091289", "map_id": "none", "name": "HEXB cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2105025", "map_id": "CHEBI:63873", "name": "IdoA-GalNAc(4S)-GlcA-Gal-Gal-Xyl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10060827", "map_id": "none", "name": "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2104993", "map_id": "CHEBI:63868", "name": "CHEBI:63868 chain", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10060842", "map_id": "none", "name": "HYAL1 hydrolyses Chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2065257", "map_id": "none", "name": "Chondroitin chains", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "CHEBI:63512", "map_id": "CHEBI:63512", "name": "CHEBI:63512", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63513", "map_id": "CHEBI:63513", "name": "CHEBI:63513", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63515", "map_id": "CHEBI:63515", "name": "CHEBI:63515", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2065239", "map_id": "CHEBI:63511", "name": "Chondroitin chain", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10060839", "map_id": "none", "name": "HYAL1-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "F1MSK8", "map_id": "F1MSK8", "name": "HYAL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000611", "map_id": "ENSBTAT00000000611", "name": "HYAL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060829", "map_id": "none", "name": "ARSB hydrolyses C4S/C6S chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2065251", "map_id": "none", "name": "C4S/C6S chains", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_10060028", "map_id": "none", "name": "ARSB:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10062655", "map_id": "none", "name": "DSPG and CSPG translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10062551", "map_id": "none", "name": "DSPGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P21809", "map_id": "P21809", "name": "BGN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047242", "map_id": "ENSBTAT00000047242", "name": "BGN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MY84", "map_id": "F1MY84", "name": "CSPG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016206", "map_id": "ENSBTAT00000016206", "name": "CSPG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCM1", "map_id": "Q0VCM1", "name": "CSPG5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002979", "map_id": "ENSBTAT00000002979", "name": "CSPG5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21793", "map_id": "P21793", "name": "DCN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2Y8", "map_id": "F1N2Y8", "name": "NCAN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002312", "map_id": "ENSBTAT00000002312", "name": "NCAN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062589", "map_id": "none", "name": "CSPGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10062627", "map_id": "none", "name": "CSPGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_10062653", "map_id": "none", "name": "DSPGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10060031", "map_id": "none", "name": "ARSB hydrolyses DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2065231", "map_id": "CHEBI:63519", "name": "ChEBI:63519 chain", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10063807", "map_id": "none", "name": "HEXA cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10061642", "map_id": "none", "name": "CHPF,CHSY3 transfer GalNAc to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061629", "map_id": "none", "name": "chondroitin(2)-core proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061574", "map_id": "none", "name": "chondroitin(3)-core proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061639", "map_id": "none", "name": "CHPF,CHSY3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BMM8", "map_id": "E1BMM8", "name": "CHPF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027366", "map_id": "ENSBTAT00000027366", "name": "CHPF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N783", "map_id": "F1N783", "name": "CHSY3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019521", "map_id": "ENSBTAT00000019521", "name": "CHSY3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061612", "map_id": "none", "name": "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061591", "map_id": "none", "name": "C4S-PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061609", "map_id": "none", "name": "CHST9,11,12,13", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1N663", "map_id": "F1N663", "name": "CHST11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014069", "map_id": "ENSBTAT00000014069", "name": "CHST11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M362", "map_id": "A0A3Q1M362", "name": "CHST12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073469", "map_id": "ENSBTAT00000073469", "name": "CHST12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLZ9", "map_id": "A6QLZ9", "name": "CHST13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011567", "map_id": "ENSBTAT00000011567", "name": "CHST13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTD8", "map_id": "A0A3Q1MTD8", "name": "CHST9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068924", "map_id": "ENSBTAT00000068924", "name": "CHST9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10062463", "map_id": "none", "name": "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10062450", "map_id": "none", "name": "C6S-PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062460", "map_id": "none", "name": "CHST3,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "G3X6P1", "map_id": "G3X6P1", "name": "CHST7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010069", "map_id": "ENSBTAT00000010069", "name": "CHST7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPN4", "map_id": "E1BPN4", "name": "CHST3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074793", "map_id": "ENSBTAT00000074793", "name": "CHST3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061651", "map_id": "none", "name": "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1889970", "map_id": "CHEBI:17200", "name": "UDP-GlcA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10061557", "map_id": "none", "name": "chondroitin(1)-core proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061648", "map_id": "none", "name": "CHPF,CHPF2,CHSY3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1B9D0", "map_id": "E1B9D0", "name": "CHPF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019108", "map_id": "ENSBTAT00000019108", "name": "CHPF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063014", "map_id": "none", "name": "CSPG is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10063012", "map_id": "none", "name": "CSPGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10061402", "map_id": "none", "name": "B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061238", "map_id": "none", "name": "xylosyl-core proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061388", "map_id": "none", "name": "Gal-Xyl-proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061399", "map_id": "F6Q1U8", "name": "B4GALT7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000035663", "map_id": "ENSBTAT00000035663", "name": "B4GALT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061251", "map_id": "none", "name": "XYLTs transfer Xyl to core protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061200", "map_id": "none", "name": "GAG core proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_742361", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10061248", "map_id": "none", "name": "XYLT1, XYLT2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1N211", "map_id": "F1N211", "name": "XYLT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007264", "map_id": "ENSBTAT00000007264", "name": "XYLT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSF3", "map_id": "A0A3Q1LSF3", "name": "XYLT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070229", "map_id": "ENSBTAT00000070229", "name": "XYLT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061395", "map_id": "none", "name": "B3GALT6 transfers Gal to the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061289", "map_id": "none", "name": "Gal-Gal-Xyl-proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061392", "map_id": "F1MVH6", "name": "B3GALT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000057493", "map_id": "ENSBTAT00000057493", "name": "B3GALT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061350", "map_id": "none", "name": "B3GAT dimers transfer GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061327", "map_id": "none", "name": "GlcA-Gal-Gal-Xyl-proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10061347", "map_id": "none", "name": "B3GAT dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1M0B6", "map_id": "A0A3Q1M0B6", "name": "B3GAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083529", "map_id": "ENSBTAT00000083529", "name": "B3GAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LG25", "map_id": "A0A3Q1LG25", "name": "B3GAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080834", "map_id": "ENSBTAT00000080834", "name": "B3GAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQ60", "map_id": "F1MQ60", "name": "B3GAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070592", "map_id": "ENSBTAT00000070592", "name": "B3GAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091286", "map_id": "none", "name": "B3GAT3 dimer transfers GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10061345", "map_id": "none", "name": "B3GAT3:Mn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10062697", "map_id": "none", "name": "CHST14 transfers SO4(2-) to GalNAc in dermatan or DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10062676", "map_id": "none", "name": "CHST14 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062690", "map_id": "none", "name": "CHST14 products", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062694", "map_id": "A3KMX1", "name": "CHST14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000005795", "map_id": "ENSBTAT00000005795", "name": "CHST14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10062701", "map_id": "none", "name": "DSPGs are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10062699", "map_id": "none", "name": "DSPGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10062508", "map_id": "none", "name": "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10062465", "map_id": "none", "name": "DSE,DSEL substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062501", "map_id": "none", "name": "DSE,DSEL products", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062505", "map_id": "F1ME12", "name": "DSEL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000056960", "map_id": "ENSBTAT00000056960", "name": "DSEL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10062674", "map_id": "none", "name": "Dermatan sulfate can be further sulfated on position 2 of iduronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10062482", "map_id": "none", "name": "D4S-PGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062667", "map_id": "none", "name": "D2,4(S)2-PG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10062671", "map_id": "A0A3Q1M5X6", "name": "UST", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000068674", "map_id": "ENSBTAT00000068674", "name": "UST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039887", "map_id": "none", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174370", "map_id": "CHEBI:17709", "name": "APS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158471", "map_id": "CHEBI:17980", "name": "PAPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039884", "map_id": "none", "name": "PAPSS1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC88", "map_id": "Q0VC88", "name": "PAPSS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070040", "map_id": "ENSBTAT00000070040", "name": "PAPSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6R031", "map_id": "F6R031", "name": "PAPSS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017229", "map_id": "ENSBTAT00000017229", "name": "PAPSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039890", "map_id": "none", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174375", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10051570", "map_id": "none", "name": "SLC35B2,3 transport cytosolic PAPS to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10051567", "map_id": "Q3ZBB0", "name": "SLC35B2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000010620", "map_id": "ENSBTAT00000010620", "name": "SLC35B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048727", "map_id": "none", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_427648", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048724", "map_id": "F1N3J7", "name": "SLC26A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000019462", "map_id": "ENSBTAT00000019462", "name": "SLC26A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064353", "map_id": "none", "name": "HAS1,2,3 mediate the polymerisation of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_2142867", "map_id": "CHEBI:64024", "name": "GlcA-b1,3-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142896", "map_id": "none", "name": "HA polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_2162224", "map_id": "CHEBI:64024", "name": "GlcA-\u03b21,3-GlcNAc", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10064350", "map_id": "A0A3Q1LP80", "name": "HAS3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071722", "map_id": "ENSBTAT00000071722", "name": "HAS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064393", "map_id": "none", "name": "Receptor-mediated uptake of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10064359", "map_id": "Q8SQG8", "name": "HYAL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000070191", "map_id": "ENSBTAT00000070191", "name": "HYAL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064373", "map_id": "none", "name": "HARs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MJE8", "map_id": "A0A3Q1MJE8", "name": "HMMR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080269", "map_id": "ENSBTAT00000080269", "name": "HMMR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6UC88", "map_id": "Q6UC88", "name": "LYVE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001061", "map_id": "ENSBTAT00000001061", "name": "LYVE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYW1", "map_id": "F1MYW1", "name": "STAB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007896", "map_id": "ENSBTAT00000007896", "name": "STAB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2160848", "map_id": "none", "name": "HA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10064375", "map_id": "none", "name": "HA:HAR:HYAL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8SQG8", "map_id": "Q8SQG8", "name": "HYAL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091291", "map_id": "none", "name": "HEXB cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2162223", "map_id": "none", "name": "GlcNAc-GlcA-GlcNAc", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10064593", "map_id": "none", "name": "HEXA cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10064355", "map_id": "none", "name": "HYAL1 hydrolyses (HA)50", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2160864", "map_id": "none", "name": "(HA)50", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_2160866", "map_id": "none", "name": "(HA)2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10064595", "map_id": "none", "name": "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10064597", "map_id": "none", "name": "GUSB tetramer hydrolyses (HA)2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "reaction_10064391", "map_id": "none", "name": "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10064388", "map_id": "none", "name": "HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LS44", "map_id": "A0A3Q1LS44", "name": "phospho-p-CHP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071051", "map_id": "ENSBTAT00000071051", "name": "phospho-p-CHP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2160894", "map_id": "none", "name": "(HA)50", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10033579", "map_id": "none", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29452", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033576", "map_id": "none", "name": "GALE:NAD+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIP2", "map_id": "A0A452DIP2", "name": "GALE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006586", "map_id": "ENSBTAT00000006586", "name": "GALE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033594", "map_id": "none", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033549", "map_id": "none", "name": "PGM:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6QEU6", "map_id": "F6QEU6", "name": "PGM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007589", "map_id": "ENSBTAT00000007589", "name": "PGM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090620", "map_id": "none", "name": "ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9033793", "map_id": "CHEBI:139351", "name": "H antigen-RBC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_9033802", "map_id": "CHEBI:139352", "name": "A antigen-RBC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090617", "map_id": "none", "name": "ABO-A:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1M8N6", "map_id": "A0A3Q1M8N6", "name": "ABO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081124", "map_id": "ENSBTAT00000081124", "name": "ABO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090703", "map_id": "none", "name": "FUT2 transfers Fuc to Type 1 chains to form H antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9036984", "map_id": "CHEBI:140162", "name": "Type 1 chain", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_9037036", "map_id": "CHEBI:140180", "name": "H antigen-sec", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090700", "map_id": "F1MUS1", "name": "FUT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000028720", "map_id": "ENSBTAT00000028720", "name": "FUT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090638", "map_id": "none", "name": "sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9034101", "map_id": "CHEBI:140180", "name": "H antigen-sec", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9034046", "map_id": "CHEBI:16650", "name": "UDP-GalNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9037066", "map_id": "CHEBI:140186", "name": "A antigen-sec", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10090635", "map_id": "none", "name": "sABO-A:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090611", "map_id": "none", "name": "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9033790", "map_id": "CHEBI:139350", "name": "Type 2 chain", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090608", "map_id": "F6Q1T7", "name": "FUT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000023560", "map_id": "ENSBTAT00000023560", "name": "FUT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090645", "map_id": "none", "name": "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9034065", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9037067", "map_id": "CHEBI:140187", "name": "B antigen-sec", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10090642", "map_id": "none", "name": "sABO-B:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090631", "map_id": "none", "name": "ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9033798", "map_id": "CHEBI:139353", "name": "B antigen-RBC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090628", "map_id": "none", "name": "ABO-B:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10090856", "map_id": "none", "name": "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605649", "map_id": "CHEBI:140919", "name": "Type 1 DSGG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_9605651", "map_id": "CHEBI:140915", "name": "dsLeA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10090797", "map_id": "none", "name": "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605593", "map_id": "CHEBI:140911", "name": "LeX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090794", "map_id": "none", "name": "FUT4,5,9(10,11)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1MDG4", "map_id": "F1MDG4", "name": "FUT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056091", "map_id": "ENSBTAT00000056091", "name": "FUT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBS8", "map_id": "F1MBS8", "name": "FUT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N751", "map_id": "F1N751", "name": "FUT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010501", "map_id": "ENSBTAT00000010501", "name": "FUT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090799", "map_id": "none", "name": "FUT3 transfers Fuc to Type 1 chains to form LeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605607", "map_id": "CHEBI:140878", "name": "LeA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10090819", "map_id": "none", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9604808", "map_id": "CHEBI:140876", "name": "GlcNAc-\u03b21,3-Gal-R", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090816", "map_id": "none", "name": "B3GALTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q2HJA3", "map_id": "Q2HJA3", "name": "B3GALT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036248", "map_id": "ENSBTAT00000036248", "name": "B3GALT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSJ4", "map_id": "F1MSJ4", "name": "B3GALT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031889", "map_id": "ENSBTAT00000031889", "name": "B3GALT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0R9", "map_id": "Q3T0R9", "name": "B3GALT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022206", "map_id": "ENSBTAT00000022206", "name": "B3GALT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090851", "map_id": "none", "name": "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605685", "map_id": "CHEBI:140918", "name": "Type 2 MSGG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090848", "map_id": "none", "name": "ST3GAL3,4,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10090867", "map_id": "none", "name": "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605661", "map_id": "CHEBI:140916", "name": "sLeX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10090864", "map_id": "none", "name": "FUT3,5,6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "G3MZR2", "map_id": "G3MZR2", "name": "FUT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066072", "map_id": "ENSBTAT00000066072", "name": "FUT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090802", "map_id": "none", "name": "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605595", "map_id": "CHEBI:140917", "name": "Type 1 MSGG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10054713", "map_id": "A0A3Q1LUC6", "name": "ST3GAL3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10090772", "map_id": "none", "name": "FUT2 transfers Fuc to LeA to form LeB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605394", "map_id": "CHEBI:140910", "name": "LeB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10090774", "map_id": "none", "name": "FUT2 transfers Fuc to LeX to form LeY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605586", "map_id": "CHEBI:140912", "name": "LeY", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10090854", "map_id": "none", "name": "FUT3 transfers Fuc to Type 1 MSGG to form sLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_9605615", "map_id": "CHEBI:140914", "name": "sLeA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10090822", "map_id": "none", "name": "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10069341", "map_id": "A0A452DJH9", "name": "ST6GALNAC6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10034041", "map_id": "none", "name": "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29790", "map_id": "CHEBI:57737", "name": "XY5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29882", "map_id": "CHEBI:15721", "name": "SH7P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034038", "map_id": "none", "name": "TKT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7Z014", "map_id": "A7Z014", "name": "TKT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004892", "map_id": "ENSBTAT00000004892", "name": "TKT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033592", "map_id": "none", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31467", "map_id": "CHEBI:16938", "name": "D-Glucono-1,5-lactone 6-phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033589", "map_id": "none", "name": "G6PD dimer and tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MM55", "map_id": "A0A3Q1MM55", "name": "G6PD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067626", "map_id": "ENSBTAT00000067626", "name": "G6PD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034043", "map_id": "none", "name": "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29878", "map_id": "CHEBI:16897", "name": "E4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10034013", "map_id": "none", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29996", "map_id": "CHEBI:16863", "name": "PDG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29732", "map_id": "CHEBI:17363", "name": "RU5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034010", "map_id": "none", "name": "PGD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3S5ZPM3", "map_id": "A0A3S5ZPM3", "name": "PGD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017988", "map_id": "ENSBTAT00000017988", "name": "PGD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042801", "map_id": "none", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034029", "map_id": "none", "name": "RPE:Fe2+ dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A5D7P1", "map_id": "A5D7P1", "name": "RPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082970", "map_id": "ENSBTAT00000082970", "name": "RPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034032", "map_id": "none", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10088744", "map_id": "none", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955853", "map_id": "CHEBI:47013", "name": "D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088741", "map_id": "E1BJH7", "name": "RBKS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000044396", "map_id": "ENSBTAT00000044396", "name": "RBKS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089230", "map_id": "none", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787326", "map_id": "CHEBI:11563", "name": "dR1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787328", "map_id": "CHEBI:16132", "name": "dR5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033541", "map_id": "none", "name": "PGM2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077793", "map_id": "none", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_112016", "map_id": "CHEBI:35425", "name": "R1P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10088898", "map_id": "none", "name": "SHPK phosphorylates Sedo to Sedo7P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8959707", "map_id": "CHEBI:16802", "name": "Sedo", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088895", "map_id": "A0A3S5ZPP1", "name": "SHPK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000001095", "map_id": "ENSBTAT00000001095", "name": "SHPK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073438", "map_id": "none", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5661264", "map_id": "CHEBI:15748", "name": "D-glucuronate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5661268", "map_id": "CHEBI:13115", "name": "L-gulonate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10073435", "map_id": "Q3ZCJ2", "name": "AKR1A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000000630", "map_id": "ENSBTAT00000000630", "name": "AKR1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073431", "map_id": "none", "name": "DCXR tetramer reduces L-xylulose to xylitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5660036", "map_id": "CHEBI:17399", "name": "L-xylulose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5660033", "map_id": "CHEBI:17151", "name": "xylitol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10073428", "map_id": "none", "name": "DCXR tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5PJR3", "map_id": "A5PJR3", "name": "DCXR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085766", "map_id": "ENSBTAT00000085766", "name": "DCXR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JP75", "map_id": "Q1JP75", "name": "DCXR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080747", "map_id": "none", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799540", "map_id": "CHEBI:91284", "name": "alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429579", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6799543", "map_id": "CHEBI:91280", "name": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10080744", "map_id": "none", "name": "MAN2C1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MWT0", "map_id": "F1MWT0", "name": "MAN2C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009690", "map_id": "ENSBTAT00000009690", "name": "MAN2C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084129", "map_id": "none", "name": "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_8853396", "map_id": "CHEBI:91280", "name": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6799577", "map_id": "CHEBI:91279", "name": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6799594", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10084126", "map_id": "none", "name": "MAN2B1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "Q29451", "map_id": "Q29451", "name": "MAN2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070599", "map_id": "ENSBTAT00000070599", "name": "MAN2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080756", "map_id": "none", "name": "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_8853719", "map_id": "CHEBI:71553", "name": "GlcNAc:Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10080753", "map_id": "none", "name": "MAN2B2:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "A0A3Q1MEZ5", "map_id": "A0A3Q1MEZ5", "name": "LOC528518", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081381", "map_id": "ENSBTAT00000081381", "name": "LOC528518", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067610", "map_id": "none", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067605", "map_id": "none", "name": "oligoGlc-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MB78", "map_id": "A7MB78", "name": "GYS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007423", "map_id": "ENSBTAT00000007423", "name": "GYS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NLJ5", "map_id": "A0A3Q1NLJ5", "name": "GYG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077965", "map_id": "ENSBTAT00000077965", "name": "GYG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067607", "map_id": "none", "name": "polyGlc-GYG1:GYS1-a tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067644", "map_id": "none", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067619", "map_id": "none", "name": "oligoGlc-GYG1:GYS1-b tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10067641", "map_id": "none", "name": "polyGlc-GYG1:GYS1-b tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068748", "map_id": "none", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068745", "map_id": "none", "name": "EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VCR4", "map_id": "Q0VCR4", "name": "PPP1R3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019753", "map_id": "ENSBTAT00000019753", "name": "PPP1R3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068740", "map_id": "none", "name": "EPM2A:PPP1R3C:glycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067648", "map_id": "none", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067646", "map_id": "none", "name": "glycogen-GYG1:GYS1-b tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10067631", "map_id": "A0A3Q1MPG8", "name": "GBE1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083071", "map_id": "ENSBTAT00000083071", "name": "GBE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068752", "map_id": "none", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067627", "map_id": "none", "name": "glycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068729", "map_id": "Q0VCR4", "name": "PPP1R3C", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10068750", "map_id": "none", "name": "PPP1R3C:glycogen-GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068755", "map_id": "none", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068734", "map_id": "none", "name": "PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067634", "map_id": "none", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10067639", "map_id": "none", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067636", "map_id": "none", "name": "GYG1:GYS1-a tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067622", "map_id": "none", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067617", "map_id": "none", "name": "GYG1:GYS1-b tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090696", "map_id": "none", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10090685", "map_id": "none", "name": "glycogen-GYG1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_1605745", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10090689", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl)GYG1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_10090691", "map_id": "Q9MYM4", "name": "GAA", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000021325", "map_id": "ENSBTAT00000021325", "name": "GAA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034138", "map_id": "none", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034111", "map_id": "none", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)GYG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LZJ1", "map_id": "A0A3Q1LZJ1", "name": "GYG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085404", "map_id": "ENSBTAT00000085404", "name": "GYG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034135", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl)GYG dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10034115", "map_id": "F1MHT1", "name": "AGL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008518", "map_id": "ENSBTAT00000008518", "name": "AGL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050637", "map_id": "none", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050635", "map_id": "none", "name": "PGYM b dimer:AMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MJ28", "map_id": "F1MJ28", "name": "PYGM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001373", "map_id": "ENSBTAT00000001373", "name": "PYGM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10034078", "map_id": "none", "name": "PGYM dimer, b form", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10034118", "map_id": "none", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034099", "map_id": "none", "name": "limit dextrin-glycogenin dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10033737", "map_id": "none", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033734", "map_id": "none", "name": "ASNS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1LZA3", "map_id": "Q1LZA3", "name": "ASNS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079655", "map_id": "ENSBTAT00000079655", "name": "ASNS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078529", "map_id": "none", "name": "ASPG hydrolyses L-Asn to L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10078526", "map_id": "A0A3Q1MM30", "name": "ASPG", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000066927", "map_id": "ENSBTAT00000066927", "name": "ASPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033728", "map_id": "none", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10076130", "map_id": "none", "name": "ASPA deacetylates NAA to acetate and L-aspartate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5691492", "map_id": "CHEBI:21547", "name": "NAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076127", "map_id": "none", "name": "ASPA:Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MUZ8", "map_id": "F1MUZ8", "name": "ASPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069554", "map_id": "ENSBTAT00000069554", "name": "ASPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033716", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10076406", "map_id": "none", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5693762", "map_id": "CHEBI:76931", "name": "NAAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5693772", "map_id": "CHEBI:16953", "name": "NAASP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076403", "map_id": "none", "name": "NAALADases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MUP1", "map_id": "F1MUP1", "name": "FOLH1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009723", "map_id": "ENSBTAT00000009723", "name": "FOLH1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGS8", "map_id": "F1MGS8", "name": "NAALAD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000354", "map_id": "ENSBTAT00000000354", "name": "NAALAD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043917", "map_id": "none", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209793", "map_id": "CHEBI:17697", "name": "Ac5HT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043914", "map_id": "F1N1A1", "name": "AANAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000019543", "map_id": "ENSBTAT00000019543", "name": "AANAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043948", "map_id": "none", "name": "Tryptophan is hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29500", "map_id": "CHEBI:57912", "name": "L-Trp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_209911", "map_id": "CHEBI:17780", "name": "5HTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043945", "map_id": "none", "name": "TPH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N5Q8", "map_id": "F1N5Q8", "name": "TPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007030", "map_id": "ENSBTAT00000007030", "name": "TPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGX6", "map_id": "E1BGX6", "name": "TPH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027708", "map_id": "ENSBTAT00000027708", "name": "TPH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033681", "map_id": "none", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033678", "map_id": "none", "name": "PXLP-K314-GPT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIW8", "map_id": "A0A452DIW8", "name": "GPT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010309", "map_id": "ENSBTAT00000010309", "name": "GPT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091773", "map_id": "none", "name": "RIPK3 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070522", "map_id": "E1BKA8", "name": "RIPK3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091771", "map_id": "E1BKA8", "name": "RIPK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091769", "map_id": "E1BKA8", "name": "RIPK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10068030", "map_id": "none", "name": "FLIP(S) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035394", "map_id": "A0A3Q1MLX3", "name": "CFLAR", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10068026", "map_id": "none", "name": "DISC:procaspase-8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10068028", "map_id": "none", "name": "DISC:procaspase-8:FLIP(S)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074240", "map_id": "none", "name": "FLIP(L) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068034", "map_id": "A0A3Q1MLX3", "name": "CFLAR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10068032", "map_id": "none", "name": "DISC:procaspase-8:FLIP(L)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074254", "map_id": "none", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074251", "map_id": "none", "name": "K48pUb- BIRC2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091806", "map_id": "none", "name": "STUB1 ubiquitinates RIPK3 at K55, K363", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091797", "map_id": "none", "name": "RIPK3:STUB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B7G3", "map_id": "E1B7G3", "name": "STUB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025473", "map_id": "ENSBTAT00000025473", "name": "STUB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091803", "map_id": "none", "name": "Ub-K55,363-RIPK3:STUB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091793", "map_id": "none", "name": "O-GlcNAcylation of RIPK3 (TLR4 signaling)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091786", "map_id": "E1BKA8", "name": "RIPK3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091790", "map_id": "A0A3S5ZPK0", "name": "OGT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000045447", "map_id": "ENSBTAT00000045447", "name": "OGT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091808", "map_id": "none", "name": "MLKL binds PDCD6IP and SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072342", "map_id": "E1BKM4", "name": "PDCD6IP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023165", "map_id": "ENSBTAT00000023165", "name": "PDCD6IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045220", "map_id": "F6QH17", "name": "SDCBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026526", "map_id": "ENSBTAT00000026526", "name": "SDCBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072344", "map_id": "none", "name": "p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6QH17", "map_id": "F6QH17", "name": "SDCBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKM4", "map_id": "E1BKM4", "name": "PDCD6IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091779", "map_id": "none", "name": "ATP binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070680", "map_id": "none", "name": "(RIPK1:RIPK3)oligomer:4xMLKL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091777", "map_id": "none", "name": "(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4x(MLKL:ATP)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091810", "map_id": "none", "name": "RIPK3 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091795", "map_id": "none", "name": "STUB1:STUB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091783", "map_id": "none", "name": "MLKL binds IP4, IP5 and IP6 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994146", "map_id": "CHEBI:16155", "name": "I(1,3,4,6)P4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10070686", "map_id": "none", "name": "(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xp-T357,S358-MLKL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1629770", "map_id": "CHEBI:17401", "name": "IP6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_994141", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091781", "map_id": "none", "name": "p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10081481", "map_id": "none", "name": "NAAA hydrolyses NAEs to FAs and ethanolamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_6803725", "map_id": "none", "name": "NAEs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "CHEBI:85299", "map_id": "CHEBI:85299", "name": "CHEBI:85299", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:85263", "map_id": "CHEBI:85263", "name": "CHEBI:85263", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:71464", "map_id": "CHEBI:71464", "name": "CHEBI:71464", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:85262", "map_id": "CHEBI:85262", "name": "CHEBI:85262", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6803745", "map_id": "CHEBI:16000", "name": "ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_6803778", "map_id": "none", "name": "FAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_10081478", "map_id": "none", "name": "NAAA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "F1MN16", "map_id": "F1MN16", "name": "NAAA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025945", "map_id": "ENSBTAT00000025945", "name": "NAAA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044540", "map_id": "none", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_264618", "map_id": "CHEBI:15354", "name": "Cho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_264643", "map_id": "CHEBI:15355", "name": "AcCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044537", "map_id": "F1MLQ5", "name": "CHAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022369", "map_id": "ENSBTAT00000022369", "name": "CHAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049090", "map_id": "none", "name": "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_264638", "map_id": "CHEBI:15354", "name": "Cho", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10049087", "map_id": "Q2KI26", "name": "SLC5A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005693", "map_id": "ENSBTAT00000005693", "name": "SLC5A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071437", "map_id": "none", "name": "LIN7, CASK and APBA1 bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071423", "map_id": "A0A3Q1LPV4", "name": "CASK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000071329", "map_id": "ENSBTAT00000071329", "name": "CASK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071419", "map_id": "A0A3Q1MLH9", "name": "APBA1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000079326", "map_id": "ENSBTAT00000079326", "name": "APBA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071433", "map_id": "none", "name": "LIN7A,B,C", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q32LM6", "map_id": "Q32LM6", "name": "LIN7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070192", "map_id": "ENSBTAT00000070192", "name": "LIN7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHU4", "map_id": "A0A452DHU4", "name": "LIN7C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001914", "map_id": "ENSBTAT00000001914", "name": "LIN7C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071435", "map_id": "none", "name": "LIN7:CASK:APBA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MLH9", "map_id": "A0A3Q1MLH9", "name": "APBA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPV4", "map_id": "A0A3Q1LPV4", "name": "CASK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049583", "map_id": "none", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_352003", "map_id": "CHEBI:59888", "name": "GABA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352011", "map_id": "CHEBI:59888", "name": "GABA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049580", "map_id": "none", "name": "SLC6A GABA transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A5PJX7", "map_id": "A5PJX7", "name": "SLC6A13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019308", "map_id": "ENSBTAT00000019308", "name": "SLC6A13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPI1", "map_id": "E1BPI1", "name": "SLC6A11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038826", "map_id": "ENSBTAT00000038826", "name": "SLC6A11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052018", "map_id": "none", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052015", "map_id": "G3N354", "name": "SLC32A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_917757", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane", "complex": "false" }, { "id": "ENSBTAT00000063578", "map_id": "ENSBTAT00000063578", "name": "SLC32A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052013", "map_id": "none", "name": "Synthesis of GABA by GAD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_917757", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane" }, { "id": "species_10052010", "map_id": "none", "name": "PXLP-GAD dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_917757", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane", "complex": "true" }, { "id": "Q0VCA1", "map_id": "Q0VCA1", "name": "GAD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009547", "map_id": "ENSBTAT00000009547", "name": "GAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6X2", "map_id": "F1N6X2", "name": "GAD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010598", "map_id": "ENSBTAT00000010598", "name": "GAD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051999", "map_id": "none", "name": "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051996", "map_id": "none", "name": "PXLP-K405-GAD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_917757", "compartment_display": "clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane", "complex": "true" }, { "id": "reaction_10051989", "map_id": "none", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_880046", "map_id": "CHEBI:57706", "name": "SUCCSA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10051986", "map_id": "none", "name": "ALDH5A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BDP3", "map_id": "E1BDP3", "name": "ALDH5A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029203", "map_id": "ENSBTAT00000029203", "name": "ALDH5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033755", "map_id": "none", "name": "glutamine + H2O => glutamate + NH4+ [GLS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113522", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033752", "map_id": "none", "name": "GLS2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BHZ6", "map_id": "E1BHZ6", "name": "GLS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012233", "map_id": "ENSBTAT00000012233", "name": "GLS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044461", "map_id": "none", "name": "L-Glutamine transport into neurons", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_212615", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10044076", "map_id": "none", "name": "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10044069", "map_id": "none", "name": "SLC1A1-3,6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MJN4", "map_id": "F1MJN4", "name": "SLC1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025456", "map_id": "ENSBTAT00000025456", "name": "SLC1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H774", "map_id": "A6H774", "name": "SLC1A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017953", "map_id": "ENSBTAT00000017953", "name": "SLC1A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46411", "map_id": "P46411", "name": "SLC1A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024287", "map_id": "ENSBTAT00000024287", "name": "SLC1A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUT8", "map_id": "F1MUT8", "name": "SLC1A7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016615", "map_id": "ENSBTAT00000016615", "name": "SLC1A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MR13", "map_id": "A0A3Q1MR13", "name": "SLC1A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069455", "map_id": "ENSBTAT00000069455", "name": "SLC1A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044074", "map_id": "Q5E9M1", "name": "ARL6IP5", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000028661", "map_id": "ENSBTAT00000028661", "name": "ARL6IP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033746", "map_id": "none", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033743", "map_id": "none", "name": "GLUL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P15103", "map_id": "P15103", "name": "GLUL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074216", "map_id": "ENSBTAT00000074216", "name": "GLUL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044086", "map_id": "none", "name": "glutamate uptake by astrocytes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10044083", "map_id": "none", "name": "Astrocytic EAATs", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10054361", "map_id": "none", "name": "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054358", "map_id": "none", "name": "GABR heteropentamers:GABA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MA32", "map_id": "A0A3Q1MA32", "name": "GABRG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068615", "map_id": "ENSBTAT00000068615", "name": "GABRG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHX4", "map_id": "F1MHX4", "name": "GABRA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015688", "map_id": "ENSBTAT00000015688", "name": "GABRA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E50", "map_id": "Q08E50", "name": "GABRA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080524", "map_id": "ENSBTAT00000080524", "name": "GABRA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BE96", "map_id": "E1BE96", "name": "GABRA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017637", "map_id": "ENSBTAT00000017637", "name": "GABRA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08219", "map_id": "P08219", "name": "GABRA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009483", "map_id": "ENSBTAT00000009483", "name": "GABRA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08220", "map_id": "P08220", "name": "GABRB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023711", "map_id": "ENSBTAT00000023711", "name": "GABRB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJH4", "map_id": "E1BJH4", "name": "GABRQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060999", "map_id": "ENSBTAT00000060999", "name": "GABRQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054372", "map_id": "none", "name": "GABRR pentamers:GABA transports extracellular Cl- to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054369", "map_id": "none", "name": "GABRR pentamers:GABA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B988", "map_id": "E1B988", "name": "GABRR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001857", "map_id": "ENSBTAT00000001857", "name": "GABRR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051085", "map_id": "none", "name": "GRIK3 homomer binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10050486", "map_id": "none", "name": "GRIK 3 homomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10051083", "map_id": "none", "name": "GRIK3 homomer glutamate complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091067", "map_id": "none", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091060", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091064", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091075", "map_id": "none", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091071", "map_id": "F6RXS3", "name": "CAMK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010230", "map_id": "ENSBTAT00000010230", "name": "CAMK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091073", "map_id": "none", "name": "CAMK1:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6RXS3", "map_id": "F6RXS3", "name": "CAMK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090547", "map_id": "none", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10090537", "map_id": "none", "name": "p-S221,T359.S363,S380,T573,T732-RSK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10090545", "map_id": "none", "name": "p-S221,T359,S363,S380,T573,T732-RSK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10054318", "map_id": "none", "name": "HTR3 pentamers:5HT transport Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054315", "map_id": "none", "name": "HTR3 pentamers:5HT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N1Q1", "map_id": "G3N1Q1", "name": "HTR3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000062928", "map_id": "ENSBTAT00000062928", "name": "HTR3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4Y2", "map_id": "F1N4Y2", "name": "HTR3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014292", "map_id": "ENSBTAT00000014292", "name": "HTR3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAL4", "map_id": "E1BAL4", "name": "LOC532114", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056946", "map_id": "ENSBTAT00000056946", "name": "LOC532114", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5G0", "map_id": "F1N5G0", "name": "LOC616094", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055354", "map_id": "ENSBTAT00000055354", "name": "LOC616094", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5J6", "map_id": "G5E5J6", "name": "HTR3C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022113", "map_id": "ENSBTAT00000022113", "name": "HTR3C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091521", "map_id": "none", "name": "HTR3A pentamer:5HT transports Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091518", "map_id": "none", "name": "HTR3A pentamer:5HT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091525", "map_id": "none", "name": "HTR3A pentamer binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091523", "map_id": "none", "name": "HTR3A pentamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051521", "map_id": "none", "name": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051518", "map_id": "none", "name": "O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MDD1", "map_id": "F1MDD1", "name": "CHRNA9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039651", "map_id": "ENSBTAT00000039651", "name": "CHRNA9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MF30", "map_id": "F1MF30", "name": "CHRNB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039752", "map_id": "ENSBTAT00000039752", "name": "CHRNB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHK0", "map_id": "E1BHK0", "name": "CHRNA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022855", "map_id": "ENSBTAT00000022855", "name": "CHRNA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQ06", "map_id": "F1MQ06", "name": "CHRNA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018679", "map_id": "ENSBTAT00000018679", "name": "CHRNA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJN8", "map_id": "A0A3Q1MJN8", "name": "CHRNB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075573", "map_id": "ENSBTAT00000075573", "name": "CHRNB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QPI7", "map_id": "A6QPI7", "name": "CHRNA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020942", "map_id": "ENSBTAT00000020942", "name": "CHRNA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8SPU7", "map_id": "Q8SPU7", "name": "CHRNA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018151", "map_id": "ENSBTAT00000018151", "name": "CHRNA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4T3", "map_id": "F1N4T3", "name": "CHRNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002910", "map_id": "ENSBTAT00000002910", "name": "CHRNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051523", "map_id": "none", "name": "Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10051516", "map_id": "none", "name": "Acetylcholine receptor containing alpha7 subunit", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051498", "map_id": "none", "name": "Activation of highly calcium permeable nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051495", "map_id": "none", "name": "0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051525", "map_id": "none", "name": "Binding of acetylcholine to highly calcium permeable acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10051493", "map_id": "none", "name": "Highly calcium permeable nicotinic acetylcholine receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10065894", "map_id": "none", "name": "TIRAP binds PIP2-rich regions in the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065890", "map_id": "A0A3Q1M4J2", "name": "TIRAP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070781", "map_id": "ENSBTAT00000070781", "name": "TIRAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065892", "map_id": "none", "name": "TIRAP:PI(4,5)P2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M4J2", "map_id": "A0A3Q1M4J2", "name": "TIRAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039217", "map_id": "none", "name": "Association of LBP with LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_166005", "map_id": "CHEBI:16412", "name": "LPS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10039213", "map_id": "G3N2G9", "name": "LOC514978", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000062921", "map_id": "ENSBTAT00000062921", "name": "LOC514978", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039215", "map_id": "none", "name": "LBP:bacterial LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "G3N2G9", "map_id": "G3N2G9", "name": "LOC514978", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039560", "map_id": "none", "name": "Dimerization of phosphorylated IRF3/IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039552", "map_id": "none", "name": "p-4S,T404-IRF3,p-S477,S479-IRF7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10039558", "map_id": "none", "name": "phosphorylated IRF3 and/or IRF7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040197", "map_id": "none", "name": "Dimerized phospho-IRF3/IRF7 is transported to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040195", "map_id": "none", "name": "phosphorylated IRF3 and/or IRF7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10085369", "map_id": "none", "name": "oxPL binds LBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_2186967", "map_id": "CHEBI:60156", "name": "oxidized phospholipids", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10085367", "map_id": "none", "name": "LBP:oxPL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081506", "map_id": "none", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_181015", "map_id": "CHEBI:28640", "name": "Lipoteichoic acid", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10081504", "map_id": "none", "name": "HC23,45-HMGB1:LTA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P10103", "map_id": "P10103", "name": "HMGB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081510", "map_id": "none", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081508", "map_id": "none", "name": "HC23,45-HMGB1:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10060783", "map_id": "none", "name": "Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060771", "map_id": "none", "name": "ATP-bound Gp96 dimer:CNPY3:TLR7/8/9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MIF7", "map_id": "A0A3Q1MIF7", "name": "CNPY3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074388", "map_id": "ENSBTAT00000074388", "name": "CNPY3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MK24", "map_id": "A0A3Q1MK24", "name": "TLR7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079344", "map_id": "ENSBTAT00000079344", "name": "TLR7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060769", "map_id": "none", "name": "Apo-GP96 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10060751", "map_id": "none", "name": "FL-TLR7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10060763", "map_id": "A0A3Q1MIF7", "name": "CNPY3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10060785", "map_id": "none", "name": "Endosomal TLRs pass through the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060757", "map_id": "none", "name": "intracellular TLR:UNC93B1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BBH4", "map_id": "E1BBH4", "name": "UNC93B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001581", "map_id": "ENSBTAT00000001581", "name": "UNC93B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060781", "map_id": "none", "name": "intracellular TLR:UNC93B1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10060773", "map_id": "none", "name": "TLR folding by chaperones GP96 and CNPY3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060749", "map_id": "A0A3Q1MK24", "name": "TLR7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10060759", "map_id": "none", "name": "Full-length TLR3/7/8/9 binds to UNC93B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10060755", "map_id": "E1BBH4", "name": "UNC93B1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10091739", "map_id": "none", "name": "C-ter TLR7 dimer binds HCQ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091735", "map_id": "none", "name": "C-ter TLR7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_9678628", "map_id": "none", "name": "HCQ", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091737", "map_id": "none", "name": "C-ter TLR7 dimer:HCQ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10066168", "map_id": "none", "name": "Activation of TAK1 complex bound to pUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066165", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066059", "map_id": "none", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066057", "map_id": "none", "name": "p-5Y-PKC-theta:DAG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066141", "map_id": "none", "name": "Recruitment of TRAF6 to CBM complex by binding to MALT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066131", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:CBM oligomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10066139", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066172", "map_id": "none", "name": "Oligomerization of p-CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066124", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:p-S552,S645-CARMA1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10066109", "map_id": "A0A3S5ZPB2", "name": "phospho-CARD11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066170", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:p-S552,S645-CARMA1 oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066127", "map_id": "none", "name": "Phosphorylation of CARMA1 by PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066122", "map_id": "A0A3S5ZPB2", "name": "CARD11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10066147", "map_id": "none", "name": "Phosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065638", "map_id": "none", "name": "Allergin:p-LYN:p-FCERI:IgE aggregate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N342", "map_id": "G3N342", "name": "IGHE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065204", "map_id": "ENSBTAT00000065204", "name": "IGHE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNU1", "map_id": "E1BNU1", "name": "phospho-MS4A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026773", "map_id": "ENSBTAT00000026773", "name": "phospho-MS4A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9BDR7", "map_id": "Q9BDR7", "name": "FCER1G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034054", "map_id": "ENSBTAT00000034054", "name": "FCER1G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066180", "map_id": "none", "name": "Oligomerization of TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066178", "map_id": "none", "name": "DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066120", "map_id": "none", "name": "Autophosphorylation of LYN kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066117", "map_id": "F1N261", "name": "LYN", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10065617", "map_id": "F1N261", "name": "phospho-LYN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10066065", "map_id": "none", "name": "Phosphorylation and activation of VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066061", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10066063", "map_id": "none", "name": "p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066082", "map_id": "none", "name": "Interaction of GRB2:SOS complex with p-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065484", "map_id": "Q0IIE2", "name": "phospho-SHC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065486", "map_id": "none", "name": "p-SHC1:GRB2:SOS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10066151", "map_id": "none", "name": "Phosphorylation of SHC by SYK kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066149", "map_id": "Q0IIE2", "name": "SHC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066049", "map_id": "none", "name": "Clustered p:LYN:p-FCERI:IgE:allergin:p-6Y-SYK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066080", "map_id": "none", "name": "PI3K associates with phosphorylated GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066076", "map_id": "none", "name": "p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10066078", "map_id": "none", "name": "p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066144", "map_id": "none", "name": "Phosphorylation of PIP2 to PIP3 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10065642", "map_id": "none", "name": "Recruitment of SYK to p-FCERI gamma subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065640", "map_id": "none", "name": "Clustered p:LYN:p-FCERI:IgE:allergin:SYK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066094", "map_id": "none", "name": "Hydrolysis of PIP2 by PLCG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066091", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MSH3", "map_id": "F1MSH3", "name": "phospho-TEC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046704", "map_id": "ENSBTAT00000046704", "name": "phospho-TEC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066052", "map_id": "none", "name": "Phosphorylation of TEC kinases by p-SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066042", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10066047", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066102", "map_id": "none", "name": "Autophosphorylation of BTK/ITK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066099", "map_id": "none", "name": "p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10081085", "map_id": "none", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane" }, { "id": "species_10081071", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane", "complex": "true" }, { "id": "Q05204", "map_id": "Q05204", "name": "LAMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045121", "map_id": "ENSBTAT00000045121", "name": "LAMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4J0", "map_id": "A0A3Q1M4J0", "name": "SIRPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072837", "map_id": "ENSBTAT00000072837", "name": "SIRPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NMT9", "map_id": "A0A3Q1NMT9", "name": "SIRPB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070673", "map_id": "ENSBTAT00000070673", "name": "SIRPB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRG6", "map_id": "F1MRG6", "name": "LOC536097", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012873", "map_id": "ENSBTAT00000012873", "name": "LOC536097", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZ44", "map_id": "F1MZ44", "name": "LOC104973826", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045380", "map_id": "ENSBTAT00000045380", "name": "LOC104973826", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCF4", "map_id": "E1BCF4", "name": "TMEM179B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012484", "map_id": "ENSBTAT00000012484", "name": "TMEM179B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MS24", "map_id": "A0A3Q1MS24", "name": "ATP6V0A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075240", "map_id": "ENSBTAT00000075240", "name": "ATP6V0A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P61285", "map_id": "P61285", "name": "DYNLL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081563", "map_id": "ENSBTAT00000081563", "name": "DYNLL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWC4", "map_id": "A7YWC4", "name": "ATAD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012676", "map_id": "ENSBTAT00000012676", "name": "ATAD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N3S2", "map_id": "G3N3S2", "name": "MGAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064122", "map_id": "ENSBTAT00000064122", "name": "MGAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLZ0", "map_id": "A6QLZ0", "name": "LGALS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043753", "map_id": "ENSBTAT00000043753", "name": "LGALS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCZ8", "map_id": "A0A3Q1MCZ8", "name": "ARL8A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067584", "map_id": "ENSBTAT00000067584", "name": "ARL8A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZT3", "map_id": "A0A3Q1LZT3", "name": "ITGAX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069265", "map_id": "ENSBTAT00000069265", "name": "ITGAX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPJ1", "map_id": "A0A3S5ZPJ1", "name": "TBC1D10C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017459", "map_id": "ENSBTAT00000017459", "name": "TBC1D10C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIW8", "map_id": "F1MIW8", "name": "DSG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018382", "map_id": "ENSBTAT00000018382", "name": "DSG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGJ5", "map_id": "E1BGJ5", "name": "CD93", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005511", "map_id": "ENSBTAT00000005511", "name": "CD93", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NNM6", "map_id": "A0A3Q1NNM6", "name": "LOC112442215", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081334", "map_id": "ENSBTAT00000081334", "name": "LOC112442215", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E574", "map_id": "G5E574", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084846", "map_id": "ENSBTAT00000084846", "name": "LILRA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E671", "map_id": "G5E671", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NNG7", "map_id": "A0A3Q1NNG7", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFM6", "map_id": "E1BFM6", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNM1", "map_id": "E1BNM1", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXU0", "map_id": "G3MXU0", "name": "LOC100852077", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084657", "map_id": "ENSBTAT00000084657", "name": "LOC100852077", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M953", "map_id": "A0A3Q1M953", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MX09", "map_id": "A0A3Q1MX09", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1V7", "map_id": "A0A3Q1N1V7", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NNA9", "map_id": "A0A3Q1NNA9", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LN32", "map_id": "A0A3Q1LN32", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWA7", "map_id": "A0A3Q1LWA7", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1J2", "map_id": "A0A3Q1M1J2", "name": "LOC100139209", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074686", "map_id": "ENSBTAT00000074686", "name": "LOC100139209", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M411", "map_id": "A0A3Q1M411", "name": "LILRA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9MYM4", "map_id": "Q9MYM4", "name": "GAA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWC4", "map_id": "A0A3Q1LWC4", "name": "PTPRN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077476", "map_id": "ENSBTAT00000077476", "name": "PTPRN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD53", "map_id": "E1BD53", "name": "DOK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035679", "map_id": "ENSBTAT00000035679", "name": "DOK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KII9", "map_id": "Q2KII9", "name": "DYNC1LI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019566", "map_id": "ENSBTAT00000019566", "name": "DYNC1LI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0T3", "map_id": "F1N0T3", "name": "LOC617406", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023242", "map_id": "ENSBTAT00000023242", "name": "LOC617406", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6PZJ9", "map_id": "F6PZJ9", "name": "CD58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084844", "map_id": "ENSBTAT00000084844", "name": "CD58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDP5", "map_id": "A2VDP5", "name": "ENPP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004547", "map_id": "ENSBTAT00000004547", "name": "ENPP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDL2", "map_id": "A2VDL2", "name": "SLC2A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5N4", "map_id": "G5E5N4", "name": "LOC107131224", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026431", "map_id": "ENSBTAT00000026431", "name": "LOC107131224", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LL92", "map_id": "A0A3Q1LL92", "name": "LOC512863", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066802", "map_id": "ENSBTAT00000066802", "name": "LOC512863", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVA6", "map_id": "A0A3Q1LVA6", "name": "SIGLEC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066593", "map_id": "ENSBTAT00000066593", "name": "SIGLEC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B6Z4", "map_id": "E1B6Z4", "name": "LOC614923", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026429", "map_id": "ENSBTAT00000026429", "name": "LOC614923", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHT5", "map_id": "E1BHT5", "name": "UBR4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020277", "map_id": "ENSBTAT00000020277", "name": "UBR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJK0", "map_id": "A5PJK0", "name": "SERPINB10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001458", "map_id": "ENSBTAT00000001458", "name": "SERPINB10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5S0", "map_id": "G5E5S0", "name": "FCAR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028846", "map_id": "ENSBTAT00000028846", "name": "FCAR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMS1", "map_id": "Q1RMS1", "name": "TCIRG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000367", "map_id": "ENSBTAT00000000367", "name": "TCIRG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHU6", "map_id": "F1MHU6", "name": "ATP6AP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020198", "map_id": "ENSBTAT00000020198", "name": "ATP6AP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMZ3", "map_id": "A0A3Q1LMZ3", "name": "NFASC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069125", "map_id": "ENSBTAT00000069125", "name": "NFASC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0JN39", "map_id": "A0JN39", "name": "COPB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008616", "map_id": "ENSBTAT00000008616", "name": "COPB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B876", "map_id": "E1B876", "name": "NCKAP1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047448", "map_id": "ENSBTAT00000047448", "name": "NCKAP1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3LUH2", "map_id": "Q3LUH2", "name": "CLEC6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032346", "map_id": "ENSBTAT00000032346", "name": "CLEC6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NBC9", "map_id": "A0A3Q1NBC9", "name": "ATP6V0C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073497", "map_id": "ENSBTAT00000073497", "name": "ATP6V0C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ67", "map_id": "A0A452DJ67", "name": "ATP6V0C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDF5", "map_id": "E1BDF5", "name": "SERPINB12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049662", "map_id": "ENSBTAT00000049662", "name": "SERPINB12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4H1", "map_id": "F1N4H1", "name": "CLEC4D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055016", "map_id": "ENSBTAT00000055016", "name": "CLEC4D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081083", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10079949", "map_id": "none", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_10079839", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "true" }, { "id": "A7MBA7", "map_id": "A7MBA7", "name": "XRCC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013758", "map_id": "ENSBTAT00000013758", "name": "XRCC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMD5", "map_id": "F1MMD5", "name": "XRCC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008020", "map_id": "ENSBTAT00000008020", "name": "XRCC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BA23", "map_id": "E1BA23", "name": "AMPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021018", "map_id": "ENSBTAT00000021018", "name": "AMPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2HJ57", "map_id": "Q2HJ57", "name": "COTL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021704", "map_id": "ENSBTAT00000021704", "name": "COTL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI43", "map_id": "A0A452DI43", "name": "PRDX4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008107", "map_id": "ENSBTAT00000008107", "name": "PRDX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRP0", "map_id": "F1MRP0", "name": "GHDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000876", "map_id": "ENSBTAT00000000876", "name": "GHDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E987", "map_id": "Q5E987", "name": "PSMA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027507", "map_id": "ENSBTAT00000027507", "name": "PSMA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68401", "map_id": "P68401", "name": "PAFAH1B2P68402", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007398", "map_id": "ENSBTAT00000007398", "name": "PAFAH1B2P68402", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZCI9", "map_id": "Q3ZCI9", "name": "CCT8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018917", "map_id": "ENSBTAT00000018917", "name": "CCT8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79105", "map_id": "P79105", "name": "S100A12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063314", "map_id": "ENSBTAT00000063314", "name": "S100A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFC3", "map_id": "A0A3Q1MFC3", "name": "S100A11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069599", "map_id": "ENSBTAT00000069599", "name": "S100A11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PKG9", "map_id": "A5PKG9", "name": "FGR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078914", "map_id": "ENSBTAT00000078914", "name": "FGR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5I2E5", "map_id": "Q5I2E5", "name": "FCN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084171", "map_id": "ENSBTAT00000084171", "name": "FCN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QP9", "map_id": "Q17QP9", "name": "PSMD14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWU9", "map_id": "F1MWU9", "name": "HSPA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057500", "map_id": "ENSBTAT00000057500", "name": "HSPA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJ46", "map_id": "Q2KJ46", "name": "PSMD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028608", "map_id": "ENSBTAT00000028608", "name": "PSMD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMV5", "map_id": "A0A3Q1LMV5", "name": "GSTP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084460", "map_id": "ENSBTAT00000084460", "name": "GSTP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHT1", "map_id": "F1MHT1", "name": "AGL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9F9", "map_id": "Q5E9F9", "name": "PSMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065774", "map_id": "ENSBTAT00000065774", "name": "PSMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SWY3", "map_id": "Q3SWY3", "name": "IMPDH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025179", "map_id": "ENSBTAT00000025179", "name": "IMPDH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJ25", "map_id": "Q2KJ25", "name": "PSMD12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003145", "map_id": "ENSBTAT00000003145", "name": "PSMD12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJA8", "map_id": "A0A452DJA8", "name": "PNP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016346", "map_id": "ENSBTAT00000016346", "name": "PNP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LX83", "map_id": "A0A3Q1LX83", "name": "PSMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001309", "map_id": "ENSBTAT00000001309", "name": "PSMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0Y5", "map_id": "Q3T0Y5", "name": "PSMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWE0", "map_id": "F1MWE0", "name": "PSMC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028983", "map_id": "ENSBTAT00000028983", "name": "PSMC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGS0", "map_id": "A0A3Q1MGS0", "name": "CDA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074118", "map_id": "ENSBTAT00000074118", "name": "CDA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A140T831", "map_id": "A0A140T831", "name": "CSTB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000683", "map_id": "ENSBTAT00000000683", "name": "CSTB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P62935", "map_id": "P62935", "name": "PPIA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015924", "map_id": "ENSBTAT00000015924", "name": "PPIA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIT4", "map_id": "A0A452DIT4", "name": "DBNL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023325", "map_id": "ENSBTAT00000023325", "name": "DBNL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DK5", "map_id": "Q58DK5", "name": "ALAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000315", "map_id": "ENSBTAT00000000315", "name": "ALAD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68103", "map_id": "P68103", "name": "EEF1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1A3", "map_id": "A0A3Q1N1A3", "name": "DYNLT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073135", "map_id": "ENSBTAT00000073135", "name": "DYNLT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N4Z1", "map_id": "A0A3Q1N4Z1", "name": "DYNLT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NLY8", "map_id": "A0A3Q1NLY8", "name": "DYNLT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIE3", "map_id": "A0A452DIE3", "name": "APRT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000841", "map_id": "ENSBTAT00000000841", "name": "APRT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPS7", "map_id": "A0A3Q1LPS7", "name": "C7H1orf35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084564", "map_id": "ENSBTAT00000084564", "name": "C7H1orf35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10079947", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10080063", "map_id": "none", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen" }, { "id": "species_10080039", "map_id": "none", "name": "Specific granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen", "complex": "true" }, { "id": "A0A3Q1LRA9", "map_id": "A0A3Q1LRA9", "name": "SLPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080425", "map_id": "ENSBTAT00000080425", "name": "SLPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33046", "map_id": "P33046", "name": "CATHL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044788", "map_id": "ENSBTAT00000044788", "name": "CATHL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPI3", "map_id": "E1BPI3", "name": "FRK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026661", "map_id": "ENSBTAT00000026661", "name": "FRK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZCL0", "map_id": "Q3ZCL0", "name": "CRISP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076131", "map_id": "ENSBTAT00000076131", "name": "CRISP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2LGB5", "map_id": "Q2LGB5", "name": "TOLLIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010835", "map_id": "ENSBTAT00000010835", "name": "TOLLIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLB1", "map_id": "A6QLB1", "name": "RAB27A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016464", "map_id": "ENSBTAT00000016464", "name": "RAB27A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2J3", "map_id": "A0A3Q1M2J3", "name": "CANT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079464", "map_id": "ENSBTAT00000079464", "name": "CANT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8Y2", "map_id": "E1B8Y2", "name": "OSCAR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000001395", "map_id": "ENSBTAP00000001395", "name": "OSCAR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC41", "map_id": "Q3ZC41", "name": "ACAA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RMV5", "map_id": "F6RMV5", "name": "LRG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003618", "map_id": "ENSBTAT00000003618", "name": "LRG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B6Z6", "map_id": "E1B6Z6", "name": "LCN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018806", "map_id": "ENSBTAT00000018806", "name": "LCN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVJ8", "map_id": "F1MVJ8", "name": "OLFM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030920", "map_id": "ENSBTAT00000030920", "name": "OLFM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MD23", "map_id": "F1MD23", "name": "CXCL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045994", "map_id": "ENSBTAT00000045994", "name": "CXCL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O46675", "map_id": "O46675", "name": "CXCL1(35-107)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039536", "map_id": "ENSBTAT00000039536", "name": "CXCL1(35-107)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P24627", "map_id": "P24627", "name": "LTF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001704", "map_id": "ENSBTAT00000001704", "name": "LTF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWG4", "map_id": "A7YWG4", "name": "GGH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009917", "map_id": "ENSBTAT00000009917", "name": "GGH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P80189", "map_id": "P80189", "name": "LYS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038266", "map_id": "ENSBTAT00000038266", "name": "LYS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MW13", "map_id": "F1MW13", "name": "DNASE1L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009806", "map_id": "ENSBTAT00000009806", "name": "DNASE1L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHQ1", "map_id": "Q3MHQ1", "name": "AOC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007133", "map_id": "ENSBTAT00000007133", "name": "AOC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IF76", "map_id": "A4IF76", "name": "MGC140461", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074688", "map_id": "ENSBTAT00000074688", "name": "MGC140461", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080061", "map_id": "none", "name": "Specific granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10080719", "map_id": "none", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane" }, { "id": "species_10080687", "map_id": "none", "name": "Specific granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799351", "compartment_display": "specific granule membrane", "complex": "true" }, { "id": "Q29455", "map_id": "Q29455", "name": "DNAJC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070817", "map_id": "ENSBTAT00000070817", "name": "DNAJC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3T5", "map_id": "F1N3T5", "name": "SLCO4C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021761", "map_id": "ENSBTAT00000021761", "name": "SLCO4C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAL1", "map_id": "A0A3Q1MAL1", "name": "TOM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070277", "map_id": "ENSBTAT00000070277", "name": "TOM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MP64", "map_id": "A0A3Q1MP64", "name": "LAIR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068539", "map_id": "ENSBTAT00000068539", "name": "LAIR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0A2", "map_id": "A0A3Q1M0A2", "name": "MOSPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074088", "map_id": "ENSBTAT00000074088", "name": "MOSPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNV7", "map_id": "A0A3Q1LNV7", "name": "MCEMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083870", "map_id": "ENSBTAT00000083870", "name": "MCEMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H797", "map_id": "A6H797", "name": "MLEC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026715", "map_id": "ENSBTAT00000026715", "name": "MLEC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFT3", "map_id": "A0A3Q1MFT3", "name": "TSPAN14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084806", "map_id": "ENSBTAT00000084806", "name": "TSPAN14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFU2", "map_id": "A4IFU2", "name": "RAP2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083623", "map_id": "ENSBTAT00000083623", "name": "RAP2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0X5", "map_id": "A0A3Q1N0X5", "name": "RAB37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068372", "map_id": "ENSBTAT00000068372", "name": "RAB37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFE2", "map_id": "E1BFE2", "name": "PTPRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020345", "map_id": "ENSBTAT00000020345", "name": "PTPRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N1F5", "map_id": "F1N1F5", "name": "MMP25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021843", "map_id": "ENSBTAT00000021843", "name": "MMP25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q58DM3", "map_id": "Q58DM3", "name": "CD53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008479", "map_id": "ENSBTAT00000008479", "name": "CD53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNL9", "map_id": "E1BNL9", "name": "CLEC5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027255", "map_id": "ENSBTAT00000027255", "name": "CLEC5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6K1", "map_id": "A0A3Q1M6K1", "name": "PTPRJ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI97", "map_id": "Q2KI97", "name": "GPR84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020710", "map_id": "ENSBTAT00000020710", "name": "GPR84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4C7", "map_id": "A0A3Q1M4C7", "name": "SLC27A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A8E4P3", "map_id": "A8E4P3", "name": "STOM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052503", "map_id": "ENSBTAT00000052503", "name": "STOM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NF89", "map_id": "A0A3Q1NF89", "name": "HVCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076616", "map_id": "ENSBTAT00000076616", "name": "HVCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTY9", "map_id": "F1MTY9", "name": "HMOX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047056", "map_id": "ENSBTAT00000047056", "name": "HMOX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN89", "map_id": "F1MN89", "name": "ADGRG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008168", "map_id": "ENSBTAT00000008168", "name": "ADGRG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N680", "map_id": "F1N680", "name": "CMTM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026019", "map_id": "ENSBTAT00000026019", "name": "CMTM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZS9", "map_id": "F1MZS9", "name": "AGPAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035230", "map_id": "ENSBTAT00000035230", "name": "AGPAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQ27", "map_id": "A0A3Q1MQ27", "name": "CEACAM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069303", "map_id": "ENSBTAT00000069303", "name": "CEACAM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMX5", "map_id": "F1MMX5", "name": "ATP8B4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069044", "map_id": "ENSBTAT00000069044", "name": "ATP8B4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2M7", "map_id": "A0A3Q1M2M7", "name": "ANO6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073921", "map_id": "ENSBTAT00000073921", "name": "ANO6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32PA1", "map_id": "Q32PA1", "name": "CD59", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002967", "map_id": "ENSBTAT00000002967", "name": "CD59", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3R7", "map_id": "F1N3R7", "name": "MS4A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026770", "map_id": "ENSBTAT00000026770", "name": "MS4A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFF5", "map_id": "A4IFF5", "name": "C3AR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026308", "map_id": "ENSBTAT00000026308", "name": "C3AR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPK7", "map_id": "A0A3Q1LPK7", "name": "ATP6V1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075634", "map_id": "ENSBTAT00000075634", "name": "ATP6V1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSR2", "map_id": "A0A3Q1MSR2", "name": "ATP6V1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M288", "map_id": "A0A3Q1M288", "name": "ATP11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085751", "map_id": "ENSBTAT00000085751", "name": "ATP11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6QRN7", "map_id": "Q6QRN7", "name": "TMBIM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005137", "map_id": "ENSBTAT00000005137", "name": "TMBIM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPW8", "map_id": "A0A3Q1LPW8", "name": "TMC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075991", "map_id": "ENSBTAT00000075991", "name": "TMC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080717", "map_id": "none", "name": "Specific granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10079391", "map_id": "none", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen" }, { "id": "species_10079319", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen", "complex": "true" }, { "id": "Q5W1C4", "map_id": "Q5W1C4", "name": "TNFAIP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080090", "map_id": "ENSBTAT00000080090", "name": "TNFAIP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MNC0", "map_id": "A0A3Q1MNC0", "name": "FTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034356", "map_id": "ENSBTAT00000034356", "name": "FTH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NGZ9", "map_id": "A0A3Q1NGZ9", "name": "FTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUL1", "map_id": "F1MUL1", "name": "FTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHK8", "map_id": "Q3MHK8", "name": "METTL7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034879", "map_id": "ENSBTAT00000034879", "name": "METTL7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBE7", "map_id": "Q3ZBE7", "name": "YPEL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032525", "map_id": "ENSBTAT00000032525", "name": "YPEL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P02070", "map_id": "P02070", "name": "HBB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057323", "map_id": "ENSBTAT00000057323", "name": "HBB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10079389", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10079199", "map_id": "none", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10079131", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "A0A452DIB1", "map_id": "A0A452DIB1", "name": "RAB18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013018", "map_id": "ENSBTAT00000013018", "name": "RAB18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDR7", "map_id": "F1MDR7", "name": "DNAJC13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003865", "map_id": "ENSBTAT00000003865", "name": "DNAJC13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK38", "map_id": "E1BK38", "name": "ABCA13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061018", "map_id": "ENSBTAT00000061018", "name": "ABCA13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11023", "map_id": "P11023", "name": "RAB3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014062", "map_id": "ENSBTAT00000014062", "name": "RAB3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MNI4", "map_id": "F1MNI4", "name": "RAB5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018777", "map_id": "ENSBTAT00000018777", "name": "RAB5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCK4", "map_id": "F1MCK4", "name": "RAB4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054453", "map_id": "ENSBTAT00000054453", "name": "RAB4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q673L2", "map_id": "Q673L2", "name": "C5AR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027807", "map_id": "ENSBTAT00000027807", "name": "C5AR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI99", "map_id": "Q2KI99", "name": "STING1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071484", "map_id": "ENSBTAT00000071484", "name": "STING1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NDL5", "map_id": "A0A3Q1NDL5", "name": "SVIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086325", "map_id": "ENSBTAT00000086325", "name": "SVIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X6D0", "map_id": "G3X6D0", "name": "FRMPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004058", "map_id": "ENSBTAT00000004058", "name": "FRMPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBS7", "map_id": "A0A3Q1MBS7", "name": "RAB6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082349", "map_id": "ENSBTAT00000082349", "name": "RAB6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPL8", "map_id": "E1BPL8", "name": "MME", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002681", "map_id": "ENSBTAT00000002681", "name": "MME", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIE6", "map_id": "F1MIE6", "name": "IGF2R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037678", "map_id": "ENSBTAT00000037678", "name": "IGF2R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJS9", "map_id": "F1MJS9", "name": "PTPRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013320", "map_id": "ENSBTAT00000013320", "name": "PTPRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MB09", "map_id": "A0A3Q1MB09", "name": "ANPEP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068383", "map_id": "ENSBTAT00000068383", "name": "ANPEP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10079197", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078929", "map_id": "none", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane" }, { "id": "species_10078881", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane", "complex": "true" }, { "id": "Q2KIW2", "map_id": "Q2KIW2", "name": "CD68", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000146", "map_id": "ENSBTAT00000000146", "name": "CD68", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T0Q9", "map_id": "Q3T0Q9", "name": "GLIPR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015396", "map_id": "ENSBTAT00000015396", "name": "GLIPR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MY77", "map_id": "G3MY77", "name": "MAGT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065645", "map_id": "ENSBTAT00000065645", "name": "MAGT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJY9", "map_id": "A5PJY9", "name": "CPNE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020644", "map_id": "ENSBTAT00000020644", "name": "CPNE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NHB1", "map_id": "A0A3Q1NHB1", "name": "SYNGR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080189", "map_id": "ENSBTAT00000080189", "name": "SYNGR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0II86", "map_id": "Q0II86", "name": "SNAP29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027666", "map_id": "ENSBTAT00000027666", "name": "SNAP29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTK4", "map_id": "F1MTK4", "name": "LPCAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001250", "map_id": "ENSBTAT00000001250", "name": "LPCAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDS4", "map_id": "A0A3Q1MDS4", "name": "RAB3D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073232", "map_id": "ENSBTAT00000073232", "name": "RAB3D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MAZ1", "map_id": "A0A3Q1MAZ1", "name": "LOC618737", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071382", "map_id": "ENSBTAT00000071382", "name": "LOC618737", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078927", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10081265", "map_id": "none", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081245", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800405", "compartment_display": "ficolin-1-rich granule lumen", "complex": "true" }, { "id": "F1MNS8", "map_id": "F1MNS8", "name": "PDAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061310", "map_id": "ENSBTAT00000061310", "name": "PDAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N0V2", "map_id": "G3N0V2", "name": "KRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065029", "map_id": "ENSBTAT00000065029", "name": "KRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RY7", "map_id": "Q29RY7", "name": "FGL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012815", "map_id": "ENSBTAT00000012815", "name": "FGL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFQ6", "map_id": "A4IFQ6", "name": "CALML5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018403", "map_id": "ENSBTAT00000018403", "name": "CALML5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P07688", "map_id": "P07688", "name": "CTSB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036795", "map_id": "ENSBTAT00000036795", "name": "CTSB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB52", "map_id": "E1BB52", "name": "CDK13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002003", "map_id": "ENSBTAT00000002003", "name": "CDK13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ01", "map_id": "A0A452DJ01", "name": "CAPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011678", "map_id": "ENSBTAT00000011678", "name": "CAPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXZ0", "map_id": "F1MXZ0", "name": "GNS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081263", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10080435", "map_id": "none", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen" }, { "id": "species_10080307", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen", "complex": "true" }, { "id": "F1MGY9", "map_id": "F1MGY9", "name": "AGA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022716", "map_id": "ENSBTAT00000022716", "name": "AGA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPJ7", "map_id": "A0A3Q1MPJ7", "name": "CPPED1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067144", "map_id": "ENSBTAT00000067144", "name": "CPPED1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBA2", "map_id": "A7MBA2", "name": "PSMD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006754", "map_id": "ENSBTAT00000006754", "name": "PSMD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QPT4", "map_id": "A6QPT4", "name": "MPO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067752", "map_id": "ENSBTAT00000067752", "name": "MPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O77834", "map_id": "O77834", "name": "PRDX6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006383", "map_id": "ENSBTAT00000006383", "name": "PRDX6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYV0", "map_id": "A0A3Q1LYV0", "name": "NHLRC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070714", "map_id": "ENSBTAT00000070714", "name": "NHLRC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLB7", "map_id": "A6QLB7", "name": "CAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017775", "map_id": "ENSBTAT00000017775", "name": "CAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBH5", "map_id": "Q3ZBH5", "name": "PA2G4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013796", "map_id": "ENSBTAT00000013796", "name": "PA2G4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHM5", "map_id": "Q3MHM5", "name": "TUBB4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074704", "map_id": "ENSBTAT00000074704", "name": "TUBB4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LUG9", "map_id": "A0A3Q1LUG9", "name": "TXNDC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076880", "map_id": "ENSBTAT00000076880", "name": "TXNDC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O46415", "map_id": "O46415", "name": "FTL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009965", "map_id": "ENSBTAT00000009965", "name": "FTL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7I6", "map_id": "F1N7I6", "name": "GCA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024550", "map_id": "ENSBTAT00000024550", "name": "GCA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N1V6", "map_id": "F1N1V6", "name": "C9H6orf120", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005121", "map_id": "ENSBTAT00000005121", "name": "C9H6orf120", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MU24", "map_id": "F1MU24", "name": "PYGB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006069", "map_id": "ENSBTAT00000006069", "name": "PYGB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJD0", "map_id": "Q2KJD0", "name": "TUBB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009158", "map_id": "ENSBTAT00000009158", "name": "TUBB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQA6", "map_id": "A0A3Q1LQA6", "name": "HRNR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072426", "map_id": "ENSBTAT00000072426", "name": "HRNR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFP1", "map_id": "E1BFP1", "name": "HEBP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000304", "map_id": "ENSBTAT00000000304", "name": "HEBP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXK8", "map_id": "G3MXK8", "name": "PRTN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064845", "map_id": "ENSBTAT00000064845", "name": "PRTN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQ81", "map_id": "A6QQ81", "name": "DSN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034528", "map_id": "ENSBTAT00000034528", "name": "DSN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ87", "map_id": "A0A452DJ87", "name": "CTSA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039203", "map_id": "ENSBTAT00000039203", "name": "CTSA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNX2", "map_id": "A6QNX2", "name": "DPP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064726", "map_id": "ENSBTAT00000064726", "name": "DPP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NEU9", "map_id": "A0A3Q1NEU9", "name": "DYNC1H1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066561", "map_id": "ENSBTAT00000066561", "name": "DYNC1H1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LKA9", "map_id": "A0A3Q1LKA9", "name": "LOC112445470", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084208", "map_id": "ENSBTAT00000084208", "name": "LOC112445470", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1ML33", "map_id": "A0A3Q1ML33", "name": "LOC519132", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073654", "map_id": "ENSBTAT00000073654", "name": "LOC519132", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMW6", "map_id": "A0A3Q1LMW6", "name": "LOC107131803", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073103", "map_id": "ENSBTAT00000073103", "name": "LOC107131803", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8B5", "map_id": "E1B8B5", "name": "LOC511106", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053165", "map_id": "ENSBTAT00000053165", "name": "LOC511106", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTS9", "map_id": "A0A3Q1LTS9", "name": "LOC522479", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068563", "map_id": "ENSBTAT00000068563", "name": "LOC522479", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMS7", "map_id": "F1MMS7", "name": "SERPINB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065330", "map_id": "ENSBTAT00000065330", "name": "SERPINB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LY36", "map_id": "A0A3Q1LY36", "name": "LOC511695", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068245", "map_id": "ENSBTAT00000068245", "name": "LOC511695", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X8C3", "map_id": "G3X8C3", "name": "LOC786410", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055709", "map_id": "ENSBTAT00000055709", "name": "LOC786410", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LIW8", "map_id": "A0A3Q1LIW8", "name": "LOC112448555", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073870", "map_id": "ENSBTAT00000073870", "name": "LOC112448555", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79345", "map_id": "P79345", "name": "NPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029271", "map_id": "ENSBTAT00000029271", "name": "NPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUP9", "map_id": "F1MUP9", "name": "VAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009715", "map_id": "ENSBTAT00000009715", "name": "VAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGC2", "map_id": "F1MGC2", "name": "RNASE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036230", "map_id": "ENSBTAT00000036230", "name": "RNASE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2H4", "map_id": "G3N2H4", "name": "AZU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063121", "map_id": "ENSBTAT00000063121", "name": "AZU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QIT9", "map_id": "F6QIT9", "name": "RNASET2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019270", "map_id": "ENSBTAT00000019270", "name": "RNASET2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04272", "map_id": "P04272", "name": "ANXA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012655", "map_id": "ENSBTAT00000012655", "name": "ANXA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MS42", "map_id": "A0A3Q1MS42", "name": "UNC13D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074408", "map_id": "ENSBTAT00000074408", "name": "UNC13D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LGT8", "map_id": "A0A3Q1LGT8", "name": "LOC112445860", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083141", "map_id": "ENSBTAT00000083141", "name": "LOC112445860", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKA1", "map_id": "E1BKA1", "name": "LOC786350", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046857", "map_id": "ENSBTAT00000046857", "name": "LOC786350", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q28050", "map_id": "Q28050", "name": "S100A7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010838", "map_id": "ENSBTAT00000010838", "name": "S100A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080433", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10079653", "map_id": "none", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane" }, { "id": "species_10079613", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane", "complex": "true" }, { "id": "Q32LK2", "map_id": "Q32LK2", "name": "CYSTM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022077", "map_id": "ENSBTAT00000022077", "name": "CYSTM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10079651", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072392", "map_id": "none", "name": "SYK binds to p-Y65,Y76-FCER1G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072358", "map_id": "none", "name": "CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "CHEBI:28808", "map_id": "CHEBI:28808", "name": "CHEBI:28808", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072390", "map_id": "none", "name": "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072395", "map_id": "none", "name": "SYK autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072360", "map_id": "none", "name": "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084636", "map_id": "none", "name": "CLEC10A binds Tn-MUC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084632", "map_id": "none", "name": "Tn antigens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10084616", "map_id": "E1BJL5", "name": "CLEC10A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000054378", "map_id": "ENSBTAT00000054378", "name": "CLEC10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084634", "map_id": "none", "name": "CLEC10A:Tn antigens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BJL5", "map_id": "E1BJL5", "name": "CLEC10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072364", "map_id": "none", "name": "PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072362", "map_id": "none", "name": "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072008", "map_id": "A0A3Q1MMD9", "name": "phospho-PLCG2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10072383", "map_id": "none", "name": "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072378", "map_id": "none", "name": "CLEC6A:FCER1G dimer:alpha-mannan", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072380", "map_id": "none", "name": "FYN, LYN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072388", "map_id": "none", "name": "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072385", "map_id": "none", "name": "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072374", "map_id": "none", "name": "CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072370", "map_id": "none", "name": "CLEC4D:FCER1G dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_5621138", "map_id": "CHEBI:82624", "name": "TDM", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10072372", "map_id": "none", "name": "CLEC4D:FCER1G dimer:TDM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072057", "map_id": "none", "name": "CARD9 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072055", "map_id": "A0A3Q1LKU2", "name": "CARD9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000074019", "map_id": "ENSBTAT00000074019", "name": "CARD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071996", "map_id": "A0A3Q1LKU2", "name": "phospho-CARD9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10071998", "map_id": "none", "name": "p-T231-CARD9 oligomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LKU2", "map_id": "A0A3Q1LKU2", "name": "CARD9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072011", "map_id": "none", "name": "p-Y753,Y759-PLCG2 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10072045", "map_id": "none", "name": "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072038", "map_id": "none", "name": "CLEC7A:1,3-beta-D-glucan", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "CHEBI:37671", "map_id": "CHEBI:37671", "name": "CHEBI:37671", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2F3", "map_id": "F1N2F3", "name": "CLEC7A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085840", "map_id": "ENSBTAT00000085840", "name": "CLEC7A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072043", "map_id": "none", "name": "1,3-beta-D-glucan:p-Y15-CLEC7A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072061", "map_id": "none", "name": "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072059", "map_id": "A0A3Q1MMD9", "name": "phospho-PLCG2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10072015", "map_id": "none", "name": "BCL10 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072000", "map_id": "none", "name": "p-T231-CARD9 oligomer:BCL10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072013", "map_id": "none", "name": "p-T231-CARD9:BCL10 oligomers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072032", "map_id": "none", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072004", "map_id": "none", "name": "DAGs:p-T507,S645,S664-PRKCD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072019", "map_id": "none", "name": "DAGs:active p-T507,S645,S664-PRKCD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072002", "map_id": "none", "name": "BCL10 binds CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10072053", "map_id": "none", "name": "TRAF6 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072049", "map_id": "none", "name": "p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072051", "map_id": "none", "name": "p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072006", "map_id": "none", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10070610", "map_id": "A0A3Q1MRR6", "name": "phospho-PRKCD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10072022", "map_id": "none", "name": "PKC-delta phosphorylates CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072017", "map_id": "A0A3Q1LKU2", "name": "CARD9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10054649", "map_id": "none", "name": "Complement factor I binds to MCP, CR1:C4b, C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054645", "map_id": "none", "name": "CD46:Cell surface:C4b", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N570", "map_id": "A0A3Q1N570", "name": "CD46", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073079", "map_id": "ENSBTAT00000073079", "name": "CD46", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054492", "map_id": "none", "name": "CFI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1MF14", "map_id": "A0A3Q1MF14", "name": "CFI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076236", "map_id": "ENSBTAT00000076236", "name": "CFI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054647", "map_id": "none", "name": "CFI:CD46, CR1:C4b, C3b complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10054494", "map_id": "none", "name": "Complement factor I complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10054490", "map_id": "A0A3Q1MF14", "name": "CFI", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10054488", "map_id": "A0A3Q1MF14", "name": "CFI", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10066238", "map_id": "none", "name": "Hydrolysis of internal thioester in C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10039322", "map_id": "none", "name": "C4b", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10066236", "map_id": "none", "name": "C4b with hydrolysed thioester", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090400", "map_id": "none", "name": "C1-Inh binds and inactivates C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10084018", "map_id": "none", "name": "Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q2KIV9", "map_id": "Q2KIV9", "name": "C1QB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014871", "map_id": "ENSBTAT00000014871", "name": "C1QB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3B0IZF8", "map_id": "A0A3B0IZF8", "name": "C1QC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014865", "map_id": "ENSBTAT00000014865", "name": "C1QC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E9E3", "map_id": "Q5E9E3", "name": "C1QA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040146", "map_id": "ENSBTAT00000040146", "name": "C1QA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGP1", "map_id": "A0A3Q1MGP1", "name": "C1R", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073935", "map_id": "ENSBTAT00000073935", "name": "C1R", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084063", "map_id": "none", "name": "Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10055971", "map_id": "none", "name": "Factor H binds host cell surface markers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1006146", "map_id": "none", "name": "Host cell surface", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10054484", "map_id": "none", "name": "Homologues of CFH", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LSC6", "map_id": "A0A3Q1LSC6", "name": "LOC519737", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069343", "map_id": "ENSBTAT00000069343", "name": "LOC519737", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MC45", "map_id": "F1MC45", "name": "LOC100336868", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029340", "map_id": "ENSBTAT00000029340", "name": "LOC100336868", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055969", "map_id": "none", "name": "CFH:Host cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087797", "map_id": "none", "name": "CD46 binds C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054643", "map_id": "none", "name": "Cell surface:C4b", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10054624", "map_id": "A0A3Q1N570", "name": "CD46", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10084020", "map_id": "none", "name": "C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10039462", "map_id": "none", "name": "Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10054678", "map_id": "none", "name": "Factor I inactivates MCP/CR1-bound C4b/C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10054675", "map_id": "none", "name": "C4c", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10054657", "map_id": "none", "name": "C4d", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10039465", "map_id": "none", "name": "Conversion of C4 into C4a and C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10039302", "map_id": "none", "name": "Complement Factor 4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10039310", "map_id": "none", "name": "C4a", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10039778", "map_id": "none", "name": "Activation of C1r", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10039759", "map_id": "none", "name": "Antigen:IgG:C1Q:2xC1R:2xC1S", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10039765", "map_id": "none", "name": "Antigen:IgG:C1Q:2x Activated C1R:2xC1S", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10039776", "map_id": "none", "name": "C-reactive protein pentamer:phosphocholine:C1Q", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "C4T8B4", "map_id": "C4T8B4", "name": "CRP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018469", "map_id": "ENSBTAT00000018469", "name": "CRP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1524071", "map_id": "CHEBI:36700", "name": "PCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039782", "map_id": "none", "name": "Activation of C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10054736", "map_id": "none", "name": "C4b binds to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_983438", "map_id": "none", "name": "Cell surface", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10053134", "map_id": "none", "name": "NLRX1 inhibits MAVS-DDX58 interaction.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10053126", "map_id": "A0A3Q1MIH6", "name": "MAVS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000085261", "map_id": "ENSBTAT00000085261", "name": "MAVS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10053130", "map_id": "F1MUU5", "name": "NLRX1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000016601", "map_id": "ENSBTAT00000016601", "name": "NLRX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10053132", "map_id": "none", "name": "MAVS:NLRX1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "F1MUU5", "map_id": "F1MUU5", "name": "NLRX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MIH6", "map_id": "A0A3Q1MIH6", "name": "MAVS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053122", "map_id": "none", "name": "ISGylation of DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053118", "map_id": "none", "name": "ISG15:UBEIL/UbcH8:CEB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10053120", "map_id": "none", "name": "ISG15:DDX58 conjugate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10053095", "map_id": "none", "name": "Interaction of PIN1 with p-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10053091", "map_id": "none", "name": "p-IRF3:p-IRF3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10053086", "map_id": "Q5BIN5", "name": "PIN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10053093", "map_id": "none", "name": "p-IRF3 dimer:PIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056088", "map_id": "none", "name": "Formation of VAF (virus-activated factor) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056080", "map_id": "none", "name": "IRF3-P:IRF7-P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10053054", "map_id": "none", "name": "CREBBP,EP300", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056086", "map_id": "none", "name": "VAF (virus-activated factor)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10053058", "map_id": "none", "name": "p-IRF7 dimer interacts with coactivator CBP/p300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10053056", "map_id": "none", "name": "CBP/p300:pIRF7:pIRF7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092318", "map_id": "none", "name": "MAVS binds TOMM70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10070254", "map_id": "Q08E34", "name": "TOMM70", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10092316", "map_id": "none", "name": "MAVS:TOMM70", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10056090", "map_id": "none", "name": "Dimerization of Phospho IRF3 or phospho IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039556", "map_id": "none", "name": "p-T,4S-IRF3:p-T,4S-IRF3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10056078", "map_id": "none", "name": "IRF3-P:IRF7-P", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056082", "map_id": "none", "name": "Translocation of phosphorylated IRF3,IRF7 dimers into nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10040189", "map_id": "none", "name": "p-T,4S-IRF3:p-T,4S-IRF3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056084", "map_id": "none", "name": "CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056076", "map_id": "none", "name": "p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066559", "map_id": "none", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066555", "map_id": "Q05B79", "name": "DHX36", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000008082", "map_id": "ENSBTAT00000008082", "name": "DHX36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3134861", "map_id": "none", "name": "Unmethylated CpG DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066557", "map_id": "none", "name": "DHX36:CpG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q05B79", "map_id": "Q05B79", "name": "DHX36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090837", "map_id": "none", "name": "p-IRF7:p-IRF7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "reaction_10066536", "map_id": "none", "name": "STING ubiquitination by TRIM32 or TRIM56", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10061500", "map_id": "none", "name": "STING:TRIM32/TRIM56", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q0VCP5", "map_id": "Q0VCP5", "name": "TRIM32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022801", "map_id": "ENSBTAT00000022801", "name": "TRIM32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066530", "map_id": "Q2KI99", "name": "STING1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10055114", "map_id": "Q0VCP5", "name": "TRIM32", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10061502", "map_id": "none", "name": "STING binds TRIM32 or TRIM56 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10061498", "map_id": "Q2KI99", "name": "STING1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10066551", "map_id": "none", "name": "DDX41 ubiquitination by TRIM21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054900", "map_id": "Q7YRV4", "name": "TRIM21", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10066540", "map_id": "A3KN07", "name": "DDX41", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000043510", "map_id": "ENSBTAT00000043510", "name": "DDX41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066548", "map_id": "none", "name": "K48polyUb-DDX41:TRIM21", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A3KN07", "map_id": "A3KN07", "name": "DDX41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066608", "map_id": "none", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_874088", "map_id": "CHEBI:16991", "name": "Double-stranded DNA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10066604", "map_id": "E1BIN9", "name": "MRE11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000011748", "map_id": "ENSBTAT00000011748", "name": "MRE11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066606", "map_id": "none", "name": "MRE11:dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BIN9", "map_id": "E1BIN9", "name": "MRE11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065388", "map_id": "none", "name": "p-T,4S-IRF3 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039546", "map_id": "Q4JF28", "name": "phospho-IRF3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10063376", "map_id": "none", "name": "Dimerized phospho-IRF3 migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10067225", "map_id": "none", "name": "p-S407,Y641-STAT6 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067208", "map_id": "F1MGJ4", "name": "phospho-STAT6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10067210", "map_id": "none", "name": "p-S407,Y641-STAT6 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067229", "map_id": "none", "name": "STING recruits TBK1 and STAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046560", "map_id": "F1MGJ4", "name": "STAT6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065393", "map_id": "none", "name": "STING:STING", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "species_10067227", "map_id": "none", "name": "STING:TBK1:STAT6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "E1BKP4", "map_id": "E1BKP4", "name": "phospho-TBK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067231", "map_id": "none", "name": "p-S407-STAT6 is phosphorylated at Tyr641", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067220", "map_id": "F1MGJ4", "name": "phospho-STAT6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10067233", "map_id": "none", "name": "TBK1 is phosphorylated within STING:TBK1:STAT6 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067218", "map_id": "none", "name": "STING:p-S172-TBK1:STAT6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "reaction_10067216", "map_id": "none", "name": "p-S407,Y641-STAT6 dimer migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067214", "map_id": "none", "name": "p-S407,Y641-STAT6 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10067223", "map_id": "none", "name": "TBK1 phosphorylates STAT6 at Ser407", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065404", "map_id": "none", "name": "STING:p-S172-TBK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "reaction_10065402", "map_id": "none", "name": "TBK1 is phosphorylated within STING:TBK1:IRF3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065395", "map_id": "none", "name": "STING:TBK1:IRF3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "species_10065400", "map_id": "none", "name": "STING:p-S172-TBK1:IRF3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "reaction_10065407", "map_id": "none", "name": "IRF3 is phosphorylated by TBK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10066880", "map_id": "none", "name": "STING binds cyclic GMP-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_3244587", "map_id": "CHEBI:71580", "name": "c-GMP-AMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10065409", "map_id": "none", "name": "STING:STING", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10066878", "map_id": "none", "name": "STING:cGAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "reaction_10090019", "map_id": "none", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8982080", "map_id": "none", "name": "c-di-AMP, c-di-GMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_2395973", "map_id": "CHEBI:49537", "name": "c-di-GMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:47037", "map_id": "CHEBI:47037", "name": "CHEBI:47037", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090017", "map_id": "none", "name": "DDX41:c-di-AMP, c-di-GMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065413", "map_id": "none", "name": "STING binds c-di-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10065411", "map_id": "none", "name": "STING:c-di-GMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "reaction_10066532", "map_id": "none", "name": "STING dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10081432", "map_id": "none", "name": "RNASEs bind bacterial LPS, PGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081428", "map_id": "none", "name": "RNASE3,RNASE7,RNASE6,(RNASE8)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P08904", "map_id": "P08904", "name": "RNASE6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011585", "map_id": "ENSBTAT00000011585", "name": "RNASE6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZA1", "map_id": "G3MZA1", "name": "LOC538679", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065979", "map_id": "ENSBTAT00000065979", "name": "LOC538679", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6803074", "map_id": "none", "name": "LPS, PGN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "true" }, { "id": "CHEBI:55478", "map_id": "CHEBI:55478", "name": "CHEBI:55478", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6789198", "map_id": "CHEBI:55424", "name": "GlcNac-(1-->4)MurNAc-L-Ala-gamma-D-Glu-L-Lys-(D-Ala)2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10081430", "map_id": "none", "name": "RNASEs 3,6,7,(8):LPS,PGN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10082008", "map_id": "none", "name": "GNLY is transferred to the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081939", "map_id": "A0A3Q1LWA5", "name": "GNLY", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000083501", "map_id": "ENSBTAT00000083501", "name": "GNLY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082006", "map_id": "A0A3Q1LWA5", "name": "GNLY", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "reaction_10056539", "map_id": "none", "name": "Cathelicidin LL-37 binds to bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10056535", "map_id": "P33046", "name": "CATHL4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8879165", "map_id": "none", "name": "Microbial cell surface", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10056537", "map_id": "none", "name": "CAMP(134-170):microbial cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10082012", "map_id": "none", "name": "GNLY binds the bacterial cell surface in the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen" }, { "id": "species_8931784", "map_id": "none", "name": "Anionic phospholipids:microbial cell surface", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10082010", "map_id": "none", "name": "GNLY:bacterial anionic lipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "true" }, { "id": "A0A3Q1LWA5", "map_id": "A0A3Q1LWA5", "name": "GNLY", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083100", "map_id": "none", "name": "LEAP2 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083096", "map_id": "Q95JC3", "name": "LEAP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000025186", "map_id": "ENSBTAT00000025186", "name": "LEAP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083098", "map_id": "none", "name": "LEAP2:bacterial phospholipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q95JC3", "map_id": "Q95JC3", "name": "LEAP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070906", "map_id": "none", "name": "LCN2:2,5DHBA binds Fe3+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10070902", "map_id": "none", "name": "LCN2:2,5DHBA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17189", "map_id": "CHEBI:17189", "name": "CHEBI:17189", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_912516", "map_id": "CHEBI:29034", "name": "Fe3+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10070904", "map_id": "none", "name": "LCN2:2,5DHBA:Fe3+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_917966", "map_id": "CHEBI:29034", "name": "Fe3+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10056416", "map_id": "none", "name": "Lactoferrin scavenges iron ions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen" }, { "id": "species_2101051", "map_id": "CHEBI:41609", "name": "CO3(2-)", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10056412", "map_id": "P24627", "name": "LTF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_1222611", "map_id": "CHEBI:29034", "name": "Fe3+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_10056414", "map_id": "none", "name": "LTF:2xFe3+:2xCO3(2-)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "true" }, { "id": "reaction_10078759", "map_id": "none", "name": "S100A7 or S100A7A binds Zn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10078755", "map_id": "none", "name": "S100A7, S100A7A:Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10078757", "map_id": "none", "name": "S100A7, S100A7A:Ca2+:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10082004", "map_id": "none", "name": "HTN1,HTN3 or HTN5 binds the bacterial anionic surface ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081994", "map_id": "A0A3Q1LX31", "name": "HSTN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000077381", "map_id": "ENSBTAT00000077381", "name": "HSTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082002", "map_id": "none", "name": "HTN1,3,5:bacterial phospholipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LX31", "map_id": "A0A3Q1LX31", "name": "HSTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081559", "map_id": "none", "name": "INTL1 binds bacterial glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081555", "map_id": "none", "name": "ITLN1 trimer:Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "G3N3R4", "map_id": "G3N3R4", "name": "ITLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064812", "map_id": "ENSBTAT00000064812", "name": "ITLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6804535", "map_id": "none", "name": "INTL1 ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "true" }, { "id": "CHEBI:42976", "map_id": "CHEBI:42976", "name": "CHEBI:42976", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59496", "map_id": "CHEBI:59496", "name": "CHEBI:59496", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:85986", "map_id": "CHEBI:85986", "name": "CHEBI:85986", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081557", "map_id": "none", "name": "INTL1:bacterial glycan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081943", "map_id": "none", "name": "GNLY binds the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081941", "map_id": "none", "name": "GNLY:bacterial anionic lipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10082967", "map_id": "none", "name": "EPPIN protein complex binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5083403", "compartment_display": "sperm plasma membrane" }, { "id": "species_10082963", "map_id": "none", "name": "EPPIN:SEMG1:LTF:CLU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5083403", "compartment_display": "sperm plasma membrane", "complex": "true" }, { "id": "A0A3Q1ME64", "map_id": "A0A3Q1ME64", "name": "SPINLW1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078640", "map_id": "ENSBTAT00000078640", "name": "SPINLW1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082965", "map_id": "none", "name": "EPC:bacterial surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5083403", "compartment_display": "sperm plasma membrane", "complex": "true" }, { "id": "reaction_10084683", "map_id": "none", "name": "LYZ binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10079373", "map_id": "P80189", "name": "LYS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10084681", "map_id": "none", "name": "LYZ:PGN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10080842", "map_id": "none", "name": "PGLYRP2 hydrolyzes bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10080839", "map_id": "none", "name": "PGLYRP2:peptidoglycan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BH94", "map_id": "E1BH94", "name": "PGLYRP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047024", "map_id": "ENSBTAT00000047024", "name": "PGLYRP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080837", "map_id": "none", "name": "PGLYRP2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_6799970", "map_id": "none", "name": "(GlcNAc+MurNac)n", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:28881", "map_id": "CHEBI:28881", "name": "CHEBI:28881", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6799975", "map_id": "CHEBI:61626", "name": "L-Ala-gamma-D-Glu-L-Lys-D-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10080844", "map_id": "none", "name": "PGLYRP2 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10084686", "map_id": "none", "name": "LYZ hydrolyzes peptidoglycans in the bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_6788991", "map_id": "none", "name": "MurNAc:Peptide", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "true" }, { "id": "CHEBI:21615", "map_id": "CHEBI:21615", "name": "CHEBI:21615", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6788982", "map_id": "CHEBI:28009", "name": "betaGlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "false" }, { "id": "reaction_10058388", "map_id": "none", "name": "Pre-pro-defensins are cleaved to remove the signal peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10058328", "map_id": "none", "name": "Pre-pro-defensins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_10058386", "map_id": "none", "name": "Pro-defensins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10081410", "map_id": "none", "name": "REG3A,REG3G binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081389", "map_id": "P23132", "name": "PTP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000086119", "map_id": "ENSBTAT00000086119", "name": "PTP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081408", "map_id": "none", "name": "REG3A(38-175), REG3G(38-175):peptidoglycan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P23132", "map_id": "P23132", "name": "PTP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082183", "map_id": "none", "name": "BPIF binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10082179", "map_id": "none", "name": "BPIFA/BPIFB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MLW2", "map_id": "F1MLW2", "name": "BPIFB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020875", "map_id": "ENSBTAT00000020875", "name": "BPIFB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MHQ2", "map_id": "F1MHQ2", "name": "BPIFA2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012052", "map_id": "ENSBTAT00000012052", "name": "BPIFA2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RMF1", "map_id": "F6RMF1", "name": "LOC112441508", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044454", "map_id": "ENSBTAT00000044454", "name": "LOC112441508", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082181", "map_id": "none", "name": "BPIFA/BPIFB:bacterial cell", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081404", "map_id": "none", "name": "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081399", "map_id": "P23132", "name": "PTP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10081401", "map_id": "P23132", "name": "PTP", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10058556", "map_id": "A7YWU9", "name": "PRSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10080831", "map_id": "none", "name": "PGLYRP3,4 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10080827", "map_id": "none", "name": "PGLYRP3,4 dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M1U5", "map_id": "A0A3Q1M1U5", "name": "PGLYRP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078335", "map_id": "ENSBTAT00000078335", "name": "PGLYRP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080829", "map_id": "none", "name": "PGLYRP3,4 dimer:peptidoglycan", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081406", "map_id": "none", "name": "REG3A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081391", "map_id": "none", "name": "REG3A(38-175):anionic phospholipids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10087601", "map_id": "none", "name": "RNASEs bind bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10087599", "map_id": "none", "name": "RNASEs 3,6,7,(8):anionic phospholipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081397", "map_id": "none", "name": "REG3A oligomerize to form a pore complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081395", "map_id": "none", "name": "REG3A hexamer:anionic phospholipid", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081385", "map_id": "none", "name": "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10081382", "map_id": "P33046", "name": "CATHL4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10080371", "map_id": "G3MXK8", "name": "PRTN3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10082977", "map_id": "none", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_6803081", "map_id": "CHEBI:16412", "name": "LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222574", "compartment_display": "cell wall", "complex": "false" }, { "id": "species_10082971", "map_id": "A1A4Q6", "name": "PI3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000056512", "map_id": "ENSBTAT00000056512", "name": "PI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082975", "map_id": "none", "name": "PI3:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A1A4Q6", "map_id": "A1A4Q6", "name": "PI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083106", "map_id": "none", "name": "ELANE, CTSG or PRTN3 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083102", "map_id": "none", "name": "ELANE, CTSG, PRTN3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10083104", "map_id": "none", "name": "ELANE,CTSG, PRTN3:microbial cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10084706", "map_id": "none", "name": "PLA2G2A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10059808", "map_id": "none", "name": "PLA2G2A:Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10084704", "map_id": "none", "name": "PLA2G2A:phospholipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10051836", "map_id": "none", "name": "PSTPIP1 binds Pyrin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051824", "map_id": "none", "name": "Pyrin trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M2Q8", "map_id": "A0A3Q1M2Q8", "name": "MEFV", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085633", "map_id": "ENSBTAT00000085633", "name": "MEFV", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051832", "map_id": "none", "name": "PSTPIP1 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N8Q0", "map_id": "A0A3Q1N8Q0", "name": "PSTPIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066698", "map_id": "ENSBTAT00000066698", "name": "PSTPIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051834", "map_id": "none", "name": "PSTPIP1 trimer:Pyrin trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10077919", "map_id": "none", "name": "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_21994", "compartment_display": "phagocytic vesicle" }, { "id": "species_1222719", "map_id": "CHEBI:16240", "name": "H2O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_6788973", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_1470067", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_1222475", "map_id": "CHEBI:15377", "name": "H2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_6789150", "map_id": "CHEBI:24757", "name": "HOCl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_10077916", "map_id": "none", "name": "MPO:ferriheme:bacterial cell surface", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "true" }, { "id": "CHEBI:55376", "map_id": "CHEBI:55376", "name": "CHEBI:55376", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084322", "map_id": "none", "name": "Lactoperoxidase (LPO) produces OSCN-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8855492", "map_id": "CHEBI:18022", "name": "SCN(-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8855489", "map_id": "CHEBI:133907", "name": "OSCN-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10084319", "map_id": "none", "name": "LPO:ferriheme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P80025", "map_id": "P80025", "name": "LPO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016986", "map_id": "ENSBTAT00000016986", "name": "LPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086405", "map_id": "none", "name": "Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen" }, { "id": "species_6789221", "map_id": "CHEBI:16301", "name": "nitrite", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_8933637", "map_id": "CHEBI:33101", "name": "NO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_10077914", "map_id": "none", "name": "MPO:ferriheme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "true" }, { "id": "reaction_10077924", "map_id": "none", "name": "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen" }, { "id": "reaction_10077926", "map_id": "none", "name": "Myeloperoxidase (MPO) binds to the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_21994", "compartment_display": "phagocytic vesicle" }, { "id": "reaction_10077921", "map_id": "none", "name": "NOX2 generates superoxide anion from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen" }, { "id": "species_1222561", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_1222461", "map_id": "CHEBI:18421", "name": "O2.-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "reaction_10077904", "map_id": "none", "name": "HV1-mediated H+ transfer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10077901", "map_id": "none", "name": "HV1 channel", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10047907", "map_id": "none", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202124", "map_id": "CHEBI:16480", "name": "NO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047904", "map_id": "A0A3Q1M6M2", "name": "NOS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000069366", "map_id": "ENSBTAT00000069366", "name": "NOS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10056531", "map_id": "none", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_10056528", "map_id": "none", "name": "V-ATPase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "Q28029", "map_id": "Q28029", "name": "ATP6V1F", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009961", "map_id": "ENSBTAT00000009961", "name": "ATP6V1F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79251", "map_id": "P79251", "name": "ATP6V1G1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000240", "map_id": "ENSBTAT00000000240", "name": "ATP6V1G1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCV6", "map_id": "Q0VCV6", "name": "ATP6V1G2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019267", "map_id": "ENSBTAT00000019267", "name": "ATP6V1G2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMV6", "map_id": "E1BMV6", "name": "ATP6V1G3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026498", "map_id": "ENSBTAT00000026498", "name": "ATP6V1G3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31408", "map_id": "P31408", "name": "ATP6V1B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024812", "map_id": "ENSBTAT00000024812", "name": "ATP6V1B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3I3", "map_id": "A0A3Q1M3I3", "name": "ATP6V1H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073116", "map_id": "ENSBTAT00000073116", "name": "ATP6V1H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32LB7", "map_id": "Q32LB7", "name": "ATP6V1E2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018250", "map_id": "ENSBTAT00000018250", "name": "ATP6V1E2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21282", "map_id": "P21282", "name": "ATP6V1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017968", "map_id": "ENSBTAT00000017968", "name": "ATP6V1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFJ9", "map_id": "A4IFJ9", "name": "ATP6V1C2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032875", "map_id": "ENSBTAT00000032875", "name": "ATP6V1C2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P81103", "map_id": "P81103", "name": "ATP6V0E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020094", "map_id": "ENSBTAT00000020094", "name": "ATP6V0E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI38", "map_id": "A0A452DI38", "name": "ATP6V0E2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007912", "map_id": "ENSBTAT00000007912", "name": "ATP6V0E2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O97681", "map_id": "O97681", "name": "ATP6V0A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009563", "map_id": "ENSBTAT00000009563", "name": "ATP6V0A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGJ7", "map_id": "E1BGJ7", "name": "ATP6V0A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005588", "map_id": "ENSBTAT00000005588", "name": "ATP6V0A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063368", "map_id": "none", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1602448", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10063365", "map_id": "none", "name": "PLD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049304", "map_id": "none", "name": "Interaction of Plectin with Integrin beta 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043043", "map_id": "A0A3Q1MRS3", "name": "PLEC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000082561", "map_id": "ENSBTAT00000082561", "name": "PLEC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044490", "map_id": "none", "name": "Integrin alpha6beta4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MRM3", "map_id": "A0A3Q1MRM3", "name": "ITGB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075471", "map_id": "ENSBTAT00000075471", "name": "ITGB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8K4", "map_id": "A0A3Q1M8K4", "name": "ITGA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085126", "map_id": "ENSBTAT00000085126", "name": "ITGA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049302", "map_id": "none", "name": "Integrin alpha 6:beta 4:Plectin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MRS3", "map_id": "A0A3Q1MRS3", "name": "PLEC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075165", "map_id": "none", "name": "SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075149", "map_id": "none", "name": "MUS81:EME1, (MUS81:EME2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3N153", "map_id": "G3N153", "name": "EME1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065898", "map_id": "ENSBTAT00000065898", "name": "EME1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8J2", "map_id": "E1B8J2", "name": "MUS81", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053203", "map_id": "ENSBTAT00000053203", "name": "MUS81", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075161", "map_id": "none", "name": "SLX1A:SLX4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q32PI0", "map_id": "Q32PI0", "name": "SLX1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011384", "map_id": "ENSBTAT00000011384", "name": "SLX1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7Q0", "map_id": "F1N7Q0", "name": "SLX4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005923", "map_id": "ENSBTAT00000005923", "name": "SLX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075163", "map_id": "none", "name": "SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075151", "map_id": "none", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075143", "map_id": "E1B8J2", "name": "MUS81", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10075139", "map_id": "none", "name": "EME1,EME2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10050458", "map_id": "none", "name": "Microtubule-independent trafficking of connexons to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050452", "map_id": "none", "name": "Connexin 26 Connexon", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_190626", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment", "complex": "true" }, { "id": "A2VE67", "map_id": "A2VE67", "name": "GJB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023167", "map_id": "ENSBTAT00000023167", "name": "GJB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050456", "map_id": "none", "name": "Connexon 26", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040857", "map_id": "none", "name": "Budding of connexon-containing transport vesicles from the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040855", "map_id": "none", "name": "Connexin 43 connexon", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P18246", "map_id": "P18246", "name": "GJA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002398", "map_id": "ENSBTAT00000002398", "name": "GJA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040800", "map_id": "none", "name": "Connexin 43 connexon in Golgi transport vesicle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "reaction_10040842", "map_id": "none", "name": "Association of Golgi transport vesicles with microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040840", "map_id": "none", "name": "connexons in Golgi transport vesicle docked to microtubules", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10036729", "map_id": "none", "name": "Cleavage of uracil by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036724", "map_id": "none", "name": "MBD4:CpG(U:G)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MUX1", "map_id": "F1MUX1", "name": "MBD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028844", "map_id": "ENSBTAT00000028844", "name": "MBD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036726", "map_id": "none", "name": "MBD4:CpG(AP)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29554", "map_id": "CHEBI:17568", "name": "Ura", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10036716", "map_id": "none", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036713", "map_id": "none", "name": "TDG:(T:G)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29692", "map_id": "CHEBI:17821", "name": "Thy", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10036767", "map_id": "none", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036764", "map_id": "none", "name": "OGG1:FapyG-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MPV2", "map_id": "F1MPV2", "name": "OGG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010226", "map_id": "ENSBTAT00000010226", "name": "OGG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036757", "map_id": "none", "name": "OGG1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5636006", "map_id": "CHEBI:29145", "name": "FapyG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10036736", "map_id": "none", "name": "Cleavage of thymine by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036733", "map_id": "none", "name": "MBD4:CpG(T:G)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036709", "map_id": "none", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036702", "map_id": "none", "name": "TDG:(Ura:Gua)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036743", "map_id": "none", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036740", "map_id": "none", "name": "TDG:EtCYT-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110233", "map_id": "CHEBI:29147", "name": "EtCYT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10089640", "map_id": "none", "name": "PPM1D dephosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089633", "map_id": "none", "name": "p-S432-RUNX2:CBFB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B9S8", "map_id": "E1B9S8", "name": "CBFB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021434", "map_id": "ENSBTAT00000021434", "name": "CBFB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MKY5", "map_id": "A0A3Q1MKY5", "name": "RUNX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066565", "map_id": "ENSBTAT00000066565", "name": "RUNX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086640", "map_id": "none", "name": "RUNX2:CBFB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113541", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10089637", "map_id": "E1BD03", "name": "PPM1D", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000012404", "map_id": "ENSBTAT00000012404", "name": "PPM1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086716", "map_id": "none", "name": "SCF(SKP2) complex binds RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086213", "map_id": "A0A3Q1MKY5", "name": "RUNX2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10086712", "map_id": "none", "name": "SCF (SKP2) complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086714", "map_id": "none", "name": "RUNX2:SCF(SKP2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089679", "map_id": "none", "name": "STUB1 polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089672", "map_id": "none", "name": "RUNX2:STUB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10055082", "map_id": "E1B7G3", "name": "STUB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10089674", "map_id": "A0A3Q1MKY5", "name": "RUNX2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089681", "map_id": "none", "name": "RUNX2 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089668", "map_id": "A0A3Q1MKY5", "name": "RUNX2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10086724", "map_id": "none", "name": "SCF(SKP2) polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086719", "map_id": "A0A3Q1MKY5", "name": "RUNX2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10089610", "map_id": "none", "name": "CDK4 phosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089605", "map_id": "none", "name": "p-S451-RUNX2:CBFB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10089607", "map_id": "none", "name": "CCND1:CDK4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089357", "map_id": "none", "name": "RUNX2 binds SOX9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089353", "map_id": "A0A3Q1MN22", "name": "SOX9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000084141", "map_id": "ENSBTAT00000084141", "name": "SOX9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089355", "map_id": "none", "name": "RUNX2:SOX9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MN22", "map_id": "A0A3Q1MN22", "name": "SOX9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074877", "map_id": "none", "name": "CX3 complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055523", "map_id": "F1MW99", "name": "RAD51C", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000020012", "map_id": "ENSBTAT00000020012", "name": "RAD51C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074873", "map_id": "A0A452DJ33", "name": "XRCC3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000013145", "map_id": "ENSBTAT00000013145", "name": "XRCC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074875", "map_id": "none", "name": "CX3 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A452DJ33", "map_id": "A0A452DJ33", "name": "XRCC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MW99", "map_id": "F1MW99", "name": "RAD51C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065177", "map_id": "none", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10064869", "map_id": "none", "name": "Condensin II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BMZ9", "map_id": "E1BMZ9", "name": "SMC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007705", "map_id": "ENSBTAT00000007705", "name": "SMC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPS0", "map_id": "F1MPS0", "name": "phospho-NCAPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039478", "map_id": "ENSBTAT00000039478", "name": "phospho-NCAPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N535", "map_id": "F1N535", "name": "phospho-NCAPG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021476", "map_id": "ENSBTAT00000021476", "name": "phospho-NCAPG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MY41", "map_id": "F1MY41", "name": "SMC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011562", "map_id": "ENSBTAT00000011562", "name": "SMC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064891", "map_id": "none", "name": "Nucleosome with H3K4me2/3:H4K20me1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10065175", "map_id": "none", "name": "Condensin II:Nucleosome with H4K20me1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10064904", "map_id": "none", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10064897", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3:H4K20me1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10064901", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10065563", "map_id": "none", "name": "MCPH1 sequesters condensin II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10065559", "map_id": "A0A3Q1M8A5", "name": "MCPH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000068774", "map_id": "ENSBTAT00000068774", "name": "MCPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050283", "map_id": "none", "name": "Homologues of SET", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2TBR3", "map_id": "Q2TBR3", "name": "SET", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027913", "map_id": "ENSBTAT00000027913", "name": "SET", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MQB1", "map_id": "A0A3Q1MQB1", "name": "LOC782688", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030281", "map_id": "ENSBTAT00000030281", "name": "LOC782688", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065561", "map_id": "none", "name": "Condensin II:MCPH1:SET", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M8A5", "map_id": "A0A3Q1M8A5", "name": "MCPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065201", "map_id": "none", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10065186", "map_id": "none", "name": "p-T210-PLK1:Phosphorylated Condensin II:Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10065198", "map_id": "none", "name": "Hyperphosphorylated Condensin II:Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10064733", "map_id": "none", "name": "MASTL (GWL) phosphorylates ARPP19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10064715", "map_id": "none", "name": "Homologues of ARPP19", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1NDP8", "map_id": "A0A3Q1NDP8", "name": "phospho-p-S62-ARPP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075206", "map_id": "ENSBTAT00000075206", "name": "phospho-p-S62-ARPP19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3X4", "map_id": "A0A3Q1M3X4", "name": "phospho-p-S62-ARPP19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064723", "map_id": "none", "name": "Homologues of p-S62-ARPP19", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10064730", "map_id": "G5E5K2", "name": "phospho-MASTL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000022950", "map_id": "ENSBTAT00000022950", "name": "phospho-MASTL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065572", "map_id": "none", "name": "MASTL phosphorylates ENSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10065567", "map_id": "A0A140T869", "name": "ENSA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000009379", "map_id": "ENSBTAT00000009379", "name": "phospho-ENSA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065570", "map_id": "A0A140T869", "name": "phospho-ENSA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10066345", "map_id": "none", "name": "NEK9 phosphorylates NEK6/NEK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066322", "map_id": "none", "name": "p-3S,2T-NEK9:NEK6/NEK7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MM88", "map_id": "F1MM88", "name": "phospho-NEK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022098", "map_id": "ENSBTAT00000022098", "name": "phospho-NEK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7J4", "map_id": "A6H7J4", "name": "NEK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070292", "map_id": "ENSBTAT00000070292", "name": "NEK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066342", "map_id": "none", "name": "p-3S,2T-NEK9: p-S206-NEK6/ p-S195-NEK7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10066324", "map_id": "none", "name": "NEK9 binds NEK6/NEK7 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066309", "map_id": "none", "name": "NEK6/NEK7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10066320", "map_id": "none", "name": "p-3S,2T-NEK9", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070705", "map_id": "none", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_5221122", "map_id": "CHEBI:29089", "name": "1,2-diacyl-glycerol 3-phosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_5221124", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10069478", "map_id": "none", "name": "LPIN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10069491", "map_id": "none", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10069470", "map_id": "none", "name": "p-S106-LPIN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10069488", "map_id": "none", "name": "CTDNEP1:CNEP1R1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q1RMV9", "map_id": "Q1RMV9", "name": "CTDNEP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025896", "map_id": "ENSBTAT00000025896", "name": "CTDNEP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBP2", "map_id": "Q3ZBP2", "name": "CNEP1R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046962", "map_id": "ENSBTAT00000046962", "name": "CNEP1R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065095", "map_id": "none", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10065087", "map_id": "none", "name": "p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10065092", "map_id": "none", "name": "p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10038371", "map_id": "none", "name": "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159447", "map_id": "CHEBI:15515", "name": "BEZ-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159564", "map_id": "CHEBI:18089", "name": "HIPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10038368", "map_id": "none", "name": "GLYAT-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MBJ0", "map_id": "A0A3Q1MBJ0", "name": "LOC104974345", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077055", "map_id": "ENSBTAT00000077055", "name": "LOC104974345", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038354", "map_id": "none", "name": "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159446", "map_id": "CHEBI:30746", "name": "BENZA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159448", "map_id": "CHEBI:16027", "name": "adenosine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10038351", "map_id": "A7MBE6", "name": "ACSM2A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000025874", "map_id": "ENSBTAT00000025874", "name": "ACSM2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039520", "map_id": "none", "name": "tBID binds to inactive BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10037233", "map_id": "Q05KI7", "name": "BAK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10037620", "map_id": "none", "name": "tBID bound to inactive BAK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q17QH5", "map_id": "Q17QH5", "name": "BID", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037237", "map_id": "none", "name": "Oligomerization of BAK at the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "reaction_10037622", "map_id": "none", "name": "tBID activates BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "reaction_10047809", "map_id": "none", "name": "GPR40 (Free fatty acid receptor 1, FFAR1) binds fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10058908", "map_id": "none", "name": "PA is hydrolysed to 1-acyl LPA by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426755", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500604", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10077777", "map_id": "none", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1602447", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10077774", "map_id": "none", "name": "DDHD1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MMR4", "map_id": "A0A3Q1MMR4", "name": "DDHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085985", "map_id": "ENSBTAT00000085985", "name": "DDHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSS2", "map_id": "F1MSS2", "name": "DDHD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017473", "map_id": "ENSBTAT00000017473", "name": "DDHD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058896", "map_id": "none", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058855", "map_id": "none", "name": "PLA2(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10058834", "map_id": "none", "name": "1-acyl LPA is acylated to PA by AGPAT5 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1500580", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10058831", "map_id": "A0A3S5ZPU2", "name": "AGPAT5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000006476", "map_id": "ENSBTAT00000006476", "name": "AGPAT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059860", "map_id": "none", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10088649", "map_id": "none", "name": "PLD6 dimer hydrolyses cardiolipin to PA and PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_189422", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_8954401", "map_id": "CHEBI:17517", "name": "PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10088630", "map_id": "none", "name": "PLD6 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "E1BE10", "map_id": "E1BE10", "name": "PLD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010531", "map_id": "ENSBTAT00000010531", "name": "PLD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088647", "map_id": "none", "name": "MIGA complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "F1MNB3", "map_id": "F1MNB3", "name": "MIGA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043938", "map_id": "ENSBTAT00000043938", "name": "MIGA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JPG0", "map_id": "Q1JPG0", "name": "MIGA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014090", "map_id": "ENSBTAT00000014090", "name": "MIGA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086248", "map_id": "none", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8878780", "map_id": "CHEBI:7794", "name": "phosphate monoester", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10086245", "map_id": "none", "name": "ALPI:2Ca2+:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N2M5", "map_id": "F1N2M5", "name": "ALPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043359", "map_id": "ENSBTAT00000043359", "name": "ALPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058923", "map_id": "none", "name": "G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10058920", "map_id": "F1MLW9", "name": "GPAT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000015359", "map_id": "ENSBTAT00000015359", "name": "GPAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035786", "map_id": "none", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10035783", "map_id": "none", "name": "AGPAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q95JH2", "map_id": "Q95JH2", "name": "AGPAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083979", "map_id": "ENSBTAT00000083979", "name": "AGPAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7D4", "map_id": "A6H7D4", "name": "AGPAT6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007532", "map_id": "ENSBTAT00000007532", "name": "AGPAT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJ33", "map_id": "A0A3Q1LJ33", "name": "LCLAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076188", "map_id": "ENSBTAT00000076188", "name": "LCLAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5P6", "map_id": "G5E5P6", "name": "AGPAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGF8", "map_id": "E1BGF8", "name": "GPAT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023396", "map_id": "ENSBTAT00000023396", "name": "GPAT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPU2", "map_id": "A0A3S5ZPU2", "name": "AGPAT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058858", "map_id": "none", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1524103", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10059114", "map_id": "none", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059111", "map_id": "none", "name": "PLD1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10051264", "map_id": "none", "name": "G3P is acylated to 1-acyl LPA by AGPAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10035769", "map_id": "A6H7D4", "name": "AGPAT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10035812", "map_id": "none", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035809", "map_id": "none", "name": "GPD1/GPD1L homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DJJ3", "map_id": "A0A452DJJ3", "name": "GPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021683", "map_id": "ENSBTAT00000021683", "name": "GPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUU4", "map_id": "A0A3Q1MUU4", "name": "GPD1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057343", "map_id": "ENSBTAT00000057343", "name": "GPD1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044235", "map_id": "none", "name": "CYP3A43 6b-hydroxylates TEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_30321", "map_id": "CHEBI:17347", "name": "TES", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_213144", "map_id": "CHEBI:34477", "name": "6BHT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044177", "map_id": "none", "name": "Homologues of CYP3A7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LZ03", "map_id": "A0A3Q1LZ03", "name": "CYP3A24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067793", "map_id": "ENSBTAT00000067793", "name": "CYP3A24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X6I4", "map_id": "G3X6I4", "name": "CYP3A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016177", "map_id": "ENSBTAT00000016177", "name": "CYP3A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29RV2", "map_id": "Q29RV2", "name": "CYP3A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3T047", "map_id": "Q3T047", "name": "CYP3A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063483", "map_id": "ENSBTAT00000063483", "name": "CYP3A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044255", "map_id": "none", "name": "CYP2W1 oxidises INDOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_216547", "map_id": "CHEBI:16881", "name": "INDOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_216598", "map_id": "CHEBI:31697", "name": "Oxindole", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044252", "map_id": "none", "name": "Cytochrome P450 (CYP2W1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MXW1", "map_id": "F1MXW1", "name": "CYP2W1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023544", "map_id": "ENSBTAT00000023544", "name": "CYP2W1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044158", "map_id": "none", "name": "CYP2S1 4-hydroxylates atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_215584", "map_id": "CHEBI:63795", "name": "4OH-atRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044155", "map_id": "A6QLC0", "name": "CYP2S1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000024282", "map_id": "ENSBTAT00000024282", "name": "CYP2S1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044242", "map_id": "none", "name": "CYP2U1 19-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_216620", "map_id": "CHEBI:63998", "name": "19HETE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044239", "map_id": "F1MFI9", "name": "CYP2U1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10044247", "map_id": "none", "name": "CYP4F11 16-hydroxylates 3OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_216621", "map_id": "CHEBI:37248", "name": "3OH-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_216612", "map_id": "CHEBI:63904", "name": "3,16DOH-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044244", "map_id": "none", "name": "Cytochrome P450 (CYP4F11 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10078408", "map_id": "none", "name": "Ubiquitinated TP53 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066675", "map_id": "none", "name": "PolyUb-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10078406", "map_id": "none", "name": "PolyUb-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10033535", "map_id": "none", "name": "CHEK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10033519", "map_id": "none", "name": "p-S15-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10033524", "map_id": "none", "name": "p-S15,S20-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10033532", "map_id": "F6R5E4", "name": "phospho-CHEK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000006518", "map_id": "ENSBTAT00000006518", "name": "phospho-CHEK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076341", "map_id": "none", "name": "ATM phosphorylates TP53 at S15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066677", "map_id": "none", "name": "TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10081470", "map_id": "none", "name": "TP53 binds ZNF385A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081466", "map_id": "A0A3Q1M6W9", "name": "ZNF385A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000070196", "map_id": "ENSBTAT00000070196", "name": "ZNF385A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081468", "map_id": "none", "name": "p-S15,S20-TP53 Tetramer:ZNF385A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M6W9", "map_id": "A0A3Q1M6W9", "name": "ZNF385A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057800", "map_id": "none", "name": "p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10057796", "map_id": "none", "name": "Cyclin E/A:CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q5E9Y0", "map_id": "Q5E9Y0", "name": "CDK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005252", "map_id": "ENSBTAT00000005252", "name": "CDK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056559", "map_id": "none", "name": "RBL2:E2F4,E2F5:TFDP1,TFDP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MKK9", "map_id": "A0A3Q1MKK9", "name": "TFDP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076561", "map_id": "ENSBTAT00000076561", "name": "TFDP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QZ4", "map_id": "Q17QZ4", "name": "TFDP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084839", "map_id": "ENSBTAT00000084839", "name": "TFDP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1Y7", "map_id": "A0A3Q1M1Y7", "name": "phospho-RBL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084739", "map_id": "ENSBTAT00000084739", "name": "phospho-RBL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBE6", "map_id": "F1MBE6", "name": "E2F4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015999", "map_id": "ENSBTAT00000015999", "name": "E2F4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057798", "map_id": "none", "name": "RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057804", "map_id": "none", "name": "p130 (RBL2) binds Cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056543", "map_id": "A0A3Q1M1Y7", "name": "RBL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10057802", "map_id": "none", "name": "RBL2:Cyclin E/A:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057808", "map_id": "none", "name": "p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056608", "map_id": "none", "name": "RBL1:E2F4:TFDP1,TFDP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BMR3", "map_id": "E1BMR3", "name": "phospho-RBL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015333", "map_id": "ENSBTAT00000015333", "name": "phospho-RBL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057806", "map_id": "none", "name": "RBL1:E2F4:DP1/2:Cyclin E/A:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057812", "map_id": "none", "name": "p107 (RBL1) binds CyclinE/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056606", "map_id": "E1BMR3", "name": "RBL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10057810", "map_id": "none", "name": "RBL1:Cyclin E/A:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10037433", "map_id": "none", "name": "Thrombin-activated PARs activate Gq", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037427", "map_id": "none", "name": "Thrombin-activated PARs:Gq (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037431", "map_id": "none", "name": "Thrombin-activated PAR:Gq (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037342", "map_id": "none", "name": "Thrombin-activated PARs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037353", "map_id": "none", "name": "Thrombin-activated PARs activate G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037346", "map_id": "none", "name": "Thrombin activated PAR:G12/13 (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037350", "map_id": "none", "name": "Thrombin activated PAR:G12/13 (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047880", "map_id": "none", "name": "F2R binds ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047872", "map_id": "F1N4J9", "name": "F2R", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10047878", "map_id": "none", "name": "F2R:ARRB2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092299", "map_id": "none", "name": "Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10092295", "map_id": "F1N4J9", "name": "F2R", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10092297", "map_id": "F1N4J9", "name": "F2R", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10037580", "map_id": "none", "name": "Activated thrombin (factor IIa) cleaves PAR3,4, activating them", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037563", "map_id": "none", "name": "PAR3, 4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037569", "map_id": "none", "name": "PAR N-teminal fragments", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10047886", "map_id": "none", "name": "SRC-1 bound to ARRB2 is not activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047884", "map_id": "none", "name": "F2R:ARRB2:MAPKs:SRC-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10041337", "map_id": "none", "name": "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193785", "map_id": "CHEBI:63849", "name": "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193747", "map_id": "CHEBI:63824", "name": "TetraHCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10041101", "map_id": "F6QQE8", "name": "CYP27A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000017935", "map_id": "ENSBTAT00000017935", "name": "CYP27A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041339", "map_id": "none", "name": "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193708", "map_id": "CHEBI:63833", "name": "5bCHOL3a,7a,24(s),27-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193716", "map_id": "CHEBI:63848", "name": "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041341", "map_id": "none", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193762", "map_id": "CHEBI:63824", "name": "TetraHCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193741", "map_id": "CHEBI:27458", "name": "25(R) TetraHCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041314", "map_id": "A0A3Q1M4C7", "name": "SLC27A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041343", "map_id": "none", "name": "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193732", "map_id": "CHEBI:27403", "name": "3,7,24THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10041361", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193707", "map_id": "CHEBI:63830", "name": "5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193728", "map_id": "CHEBI:63834", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041167", "map_id": "none", "name": "Aldo-keto reductase family", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10041363", "map_id": "none", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193777", "map_id": "CHEBI:63834", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193782", "map_id": "CHEBI:63835", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041365", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192189", "map_id": "CHEBI:37640", "name": "CHOL7a,24(S)DIOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193724", "map_id": "CHEBI:63838", "name": "4CHOL7a,24(S)DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041201", "map_id": "Q3MHF2", "name": "HSD3B7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000003028", "map_id": "ENSBTAT00000003028", "name": "HSD3B7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041367", "map_id": "none", "name": "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193720", "map_id": "CHEBI:63831", "name": "5\u03b2-CHOL3\u03b1,7\u03b1,24(s)-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041335", "map_id": "none", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193778", "map_id": "CHEBI:48736", "name": "3,7,24THCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193739", "map_id": "CHEBI:27403", "name": "3,7,24THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10038344", "map_id": "A6QM10", "name": "SLC27A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000020170", "map_id": "ENSBTAT00000020170", "name": "SLC27A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041193", "map_id": "none", "name": "CYP46A1 24-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193384", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041190", "map_id": "Q08DD0", "name": "CYP46A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000068208", "map_id": "ENSBTAT00000068208", "name": "CYP46A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041353", "map_id": "none", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193760", "map_id": "CHEBI:63829", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_213285", "map_id": "CHEBI:63831", "name": "5beta-cholestan-3alpha,7alpha,24(S)-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041355", "map_id": "none", "name": "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193793", "map_id": "CHEBI:27458", "name": "25(R) TetraHCA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193422", "map_id": "CHEBI:52050", "name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10041357", "map_id": "none", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041359", "map_id": "none", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10041217", "map_id": "none", "name": "CYP39A1 7-hydroxylates 24OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041214", "map_id": "A6H722", "name": "CYP39A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000004736", "map_id": "ENSBTAT00000004736", "name": "CYP39A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041345", "map_id": "none", "name": "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193757", "map_id": "CHEBI:48736", "name": "3,7,24THCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041347", "map_id": "none", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041349", "map_id": "none", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041108", "map_id": "E1BBT0", "name": "AKR1D1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000002172", "map_id": "ENSBTAT00000002172", "name": "AKR1D1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041351", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193745", "map_id": "CHEBI:63839", "name": "4CHOL7a,12a,24(S)TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10047659", "map_id": "none", "name": "Autophosphorylation of PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047616", "map_id": "none", "name": "Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q5E9H3", "map_id": "Q5E9H3", "name": "FES", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003828", "map_id": "ENSBTAT00000003828", "name": "FES", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFR4", "map_id": "E1BFR4", "name": "phospho-PLXNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030589", "map_id": "ENSBTAT00000030589", "name": "phospho-PLXNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2P7", "map_id": "F1N2P7", "name": "PLXNA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019327", "map_id": "ENSBTAT00000019327", "name": "PLXNA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIH8", "map_id": "F1MIH8", "name": "PLXNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001558", "map_id": "ENSBTAT00000001558", "name": "PLXNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N173", "map_id": "F1N173", "name": "PLXNA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030185", "map_id": "ENSBTAT00000030185", "name": "PLXNA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MEW1", "map_id": "F1MEW1", "name": "SEMA3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080859", "map_id": "ENSBTAT00000080859", "name": "SEMA3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047656", "map_id": "none", "name": "Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047763", "map_id": "none", "name": "Phosphorylation of LIMK-1 by PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10047618", "map_id": "none", "name": "Activation of PAK by Rac1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047612", "map_id": "none", "name": "PAK1,2,3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10047592", "map_id": "none", "name": "Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047614", "map_id": "none", "name": "PAK1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047753", "map_id": "none", "name": "Phosphorylation of CRMPs by GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047714", "map_id": "none", "name": "Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q02399", "map_id": "Q02399", "name": "phospho-CDK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010212", "map_id": "ENSBTAT00000010212", "name": "phospho-CDK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q28199", "map_id": "Q28199", "name": "CDK5R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056064", "map_id": "ENSBTAT00000056064", "name": "CDK5R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A8E641", "map_id": "A8E641", "name": "phospho-DPYSL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085592", "map_id": "ENSBTAT00000085592", "name": "phospho-DPYSL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BER6", "map_id": "E1BER6", "name": "phospho-CRMP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005625", "map_id": "ENSBTAT00000005625", "name": "phospho-CRMP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDS7", "map_id": "A2VDS7", "name": "phospho-DPYSL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023643", "map_id": "ENSBTAT00000023643", "name": "phospho-DPYSL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047750", "map_id": "none", "name": "Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047717", "map_id": "none", "name": "Phosphorylation of CRMPs by Cdk5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047695", "map_id": "none", "name": "Sema3A:Nrp-1:PlexinA:Fyn:pCdk5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047675", "map_id": "none", "name": "CRMP's tetramers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047735", "map_id": "none", "name": "Tyrosine phosphorylation of CRMPs by Fes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047586", "map_id": "none", "name": "Sema3A:NRP-1:pPlexin-A:Fyn:Fes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047732", "map_id": "none", "name": "Sema3A:NP-1:Plexin-A:Fes:CRMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10043848", "map_id": "Q5E9H3", "name": "FES", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10045244", "map_id": "none", "name": "SEMA4D interacts with CD72", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045232", "map_id": "A0A3Q1LQU8", "name": "SEMA4D", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000083792", "map_id": "ENSBTAT00000083792", "name": "SEMA4D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045240", "map_id": "E1BPB4", "name": "CD72", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000015162", "map_id": "ENSBTAT00000015162", "name": "CD72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045242", "map_id": "none", "name": "SEMA4D:CD72", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BPB4", "map_id": "E1BPB4", "name": "CD72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQU8", "map_id": "A0A3Q1LQU8", "name": "SEMA4D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045236", "map_id": "none", "name": "SEMA4D interacts with CD45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045228", "map_id": "F1MJS9", "name": "PTPRC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10045234", "map_id": "none", "name": "SEMA4D:PTPRC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089713", "map_id": "none", "name": "SLITs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10089709", "map_id": "none", "name": "SLIT2,(SLIT3)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_2299699", "map_id": "CHEBI:60924", "name": "Keratan sulfate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10089711", "map_id": "none", "name": "SLIT2,(SLIT3):Keratan sulfate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10090179", "map_id": "none", "name": "ROBOs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10043663", "map_id": "F1N739", "name": "ROBO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000061264", "map_id": "ENSBTAT00000061264", "name": "phospho-ROBO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090177", "map_id": "none", "name": "ROBO1,ROBO2:Keratan sulfate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N739", "map_id": "F1N739", "name": "phospho-ROBO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045517", "map_id": "none", "name": "Interaction of ABL with ROBO1:SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043669", "map_id": "none", "name": "ROBO1:SLIT2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10045513", "map_id": "A0A3Q1LI98", "name": "ABL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000080797", "map_id": "ENSBTAT00000080797", "name": "ABL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045515", "map_id": "none", "name": "SLIT2:ROBO1:ABL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LI98", "map_id": "A0A3Q1LI98", "name": "ABL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049024", "map_id": "none", "name": "Phosphorylation of ROBO1 by ABL kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049021", "map_id": "none", "name": "SLIT2:p-Y1073-ROBO1:ABL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10089397", "map_id": "none", "name": "SLIT2:ROBO1 binds CXCR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10089393", "map_id": "none", "name": "CXCR4:CXCL12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10089395", "map_id": "none", "name": "CXCL12:CXCR4:ROBO1:SLIT2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048935", "map_id": "none", "name": "Glypican-1 (GPC1) binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048931", "map_id": "none", "name": "GPC1:HSPG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "CHEBI:17421", "map_id": "CHEBI:17421", "name": "CHEBI:17421", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043667", "map_id": "F1MLJ7", "name": "SLIT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048933", "map_id": "none", "name": "SLIT2,SLIT2 cleavage fragments:GPC1:HSPG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043671", "map_id": "none", "name": "ROBO1 binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10048951", "map_id": "none", "name": "Recruitment of Profilin by Ena/VASP proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048947", "map_id": "none", "name": "SLIT2:ROBO1:Ena/VASP proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N214", "map_id": "F1N214", "name": "ENAH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021544", "map_id": "ENSBTAT00000021544", "name": "ENAH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048949", "map_id": "none", "name": "SLIT2:ROBO1:Ena/VASP:PFN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047449", "map_id": "none", "name": "Recruitment of Grb2 to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047443", "map_id": "none", "name": "Multiple phosphorylated FAK bound to NCAM:pFyn", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047447", "map_id": "none", "name": "Grb2:pFAK bound to NCAM1:pFyn", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047455", "map_id": "none", "name": "SOS binds Grb2 bound to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047453", "map_id": "none", "name": "Grb2:Sos:pFAK bound to NCAM1:pFyn", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047458", "map_id": "none", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10045509", "map_id": "none", "name": "DSCAM/DSCAML1 homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045505", "map_id": "A0A3Q1MBH9", "name": "DSCAM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000082055", "map_id": "ENSBTAT00000082055", "name": "DSCAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10045507", "map_id": "none", "name": "DSCAM/DSCAML1 homodimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MBH9", "map_id": "A0A3Q1MBH9", "name": "DSCAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045224", "map_id": "none", "name": "Neurofascin interacts with syntenin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10045216", "map_id": "A0A3Q1LMZ3", "name": "NFASC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10045222", "map_id": "none", "name": "Neurofascin:Syntenin-1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069192", "map_id": "none", "name": "EFNBs bind SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069057", "map_id": "none", "name": "EPHBs:EFNBs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LXH4", "map_id": "A0A3Q1LXH4", "name": "phospho-EFNB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086732", "map_id": "ENSBTAT00000086732", "name": "phospho-EFNB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0M5", "map_id": "F1N0M5", "name": "phospho-EFNB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035350", "map_id": "ENSBTAT00000035350", "name": "phospho-EFNB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML02", "map_id": "F1ML02", "name": "EPHB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006988", "map_id": "ENSBTAT00000006988", "name": "EPHB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIE4", "map_id": "E1BIE4", "name": "EPHB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037233", "map_id": "ENSBTAT00000037233", "name": "EPHB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MII5", "map_id": "F1MII5", "name": "EPHB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020455", "map_id": "ENSBTAT00000020455", "name": "EPHB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3R6", "map_id": "F1N3R6", "name": "EPHB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026780", "map_id": "ENSBTAT00000026780", "name": "EPHB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069161", "map_id": "none", "name": "SRC,FYN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10069190", "map_id": "none", "name": "EPHBs:EFNBs:SRC,FYN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069226", "map_id": "none", "name": "PAKs phosphorylate MLC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049739", "map_id": "Q5E9E2", "name": "MYL9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000021328", "map_id": "ENSBTAT00000021328", "name": "phospho-MYL9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049762", "map_id": "Q5E9E2", "name": "phospho-MYL9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069218", "map_id": "none", "name": "EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M7Q3", "map_id": "A0A3Q1M7Q3", "name": "GIT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073530", "map_id": "ENSBTAT00000073530", "name": "GIT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069418", "map_id": "none", "name": "EFNBs bind SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069416", "map_id": "none", "name": "EPHBs:EFNBs:SDCBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069221", "map_id": "none", "name": "PAKs autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069208", "map_id": "none", "name": "EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069188", "map_id": "none", "name": "EFNB:GRB4 binds GIT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069184", "map_id": "A0A3Q1M7Q3", "name": "phospho-GIT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069179", "map_id": "none", "name": "EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069186", "map_id": "none", "name": "EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069223", "map_id": "none", "name": "p-EFNB binds GRB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10045210", "map_id": "A6H720", "name": "NCK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10069177", "map_id": "none", "name": "EPHBs:p-3Y-EFNBs:SRC,FYN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069243", "map_id": "none", "name": "EPHAs bind EFNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10068993", "map_id": "none", "name": "EFNAs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069023", "map_id": "none", "name": "EPHAs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069025", "map_id": "none", "name": "EPHAs:EFNAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069131", "map_id": "none", "name": "EPH:EFN tetramers oligomerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069127", "map_id": "none", "name": "EPH-EFN dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069129", "map_id": "none", "name": "EPHAs:EFNAs,EPHBs:EFNBs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069061", "map_id": "none", "name": "EPH-ephrin oligomers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069285", "map_id": "none", "name": "gamma-secretase cleaves EPHB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069263", "map_id": "none", "name": "EPHB C-terminal fragments (CTF)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069283", "map_id": "none", "name": "EPHB CTF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069273", "map_id": "none", "name": "EPHB CTF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10069157", "map_id": "none", "name": "SFKs phosphorylate VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069152", "map_id": "none", "name": "EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069154", "map_id": "none", "name": "EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069159", "map_id": "none", "name": "p-EPHs bind VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069150", "map_id": "none", "name": "p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10048073", "map_id": "A0A3Q1MQP9", "name": "VAV2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10069194", "map_id": "none", "name": "EPHBs bind EFNBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069055", "map_id": "none", "name": "EPHBs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069037", "map_id": "none", "name": "EFNBs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069146", "map_id": "none", "name": "EPH:EFN dimers tetramerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10069121", "map_id": "none", "name": "EPH receptors autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069118", "map_id": "none", "name": "p-EPH:ephrin oligomers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069144", "map_id": "none", "name": "p190RhoGEF exchanges GTP for GDP on RHOA, activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069141", "map_id": "none", "name": "EFNBs:p-EPHBs:p-Y397-PTK2:ARHGEF28", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069435", "map_id": "none", "name": "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069428", "map_id": "none", "name": "p-EPHBs:EFNBs:RASA1:HRAS:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069432", "map_id": "none", "name": "p-EPHBs:EFNBs:RASA1:HRAS:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10069148", "map_id": "none", "name": "Recruitment of p190RhoGEF to p-FAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10069139", "map_id": "none", "name": "EFNBs:p-EPHBs:p-Y397-PTK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10069135", "map_id": "A0A3Q1LKT3", "name": "ARHGEF28", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091007", "map_id": "none", "name": "Autocleavage of ADGRG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10090998", "map_id": "A0A3Q1MTZ4", "name": "ADGRG6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000079895", "map_id": "ENSBTAT00000079895", "name": "ADGRG6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091004", "map_id": "none", "name": "ADGRG6-CTF:ADGRG6-NTF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MTZ4", "map_id": "A0A3Q1MTZ4", "name": "ADGRG6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091009", "map_id": "none", "name": "ADGRG heterodimer translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10074603", "map_id": "none", "name": "LGI4 binds ADAM22,23,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10074599", "map_id": "A6QLD0", "name": "LGI4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000025189", "map_id": "ENSBTAT00000025189", "name": "LGI4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074595", "map_id": "none", "name": "ADAM22,11,23", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NF99", "map_id": "A0A3Q1NF99", "name": "ADAM22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081521", "map_id": "ENSBTAT00000081521", "name": "ADAM22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MVZ5", "map_id": "A0A3Q1MVZ5", "name": "ADAM23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071985", "map_id": "ENSBTAT00000071985", "name": "ADAM23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPN5", "map_id": "A0A3Q1MPN5", "name": "ADAM11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077549", "map_id": "ENSBTAT00000077549", "name": "ADAM11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074601", "map_id": "none", "name": "LGI4:ADAM22,11,23", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A6QLD0", "map_id": "A6QLD0", "name": "LGI4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074641", "map_id": "none", "name": "LGI3 binds ADAM22,23,synatxin1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10074609", "map_id": "none", "name": "ADAM22,23", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10074637", "map_id": "E1BFY8", "name": "LGI3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000006011", "map_id": "ENSBTAT00000006011", "name": "LGI3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074639", "map_id": "none", "name": "LGI3;ADAM22,23,synatxin1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BFY8", "map_id": "E1BFY8", "name": "LGI3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074613", "map_id": "none", "name": "LGI2 binds ADAM22,23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10074607", "map_id": "F1MZT1", "name": "LGI2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000023124", "map_id": "ENSBTAT00000023124", "name": "LGI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074611", "map_id": "none", "name": "LGI2:ADAM22,23", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MZT1", "map_id": "F1MZT1", "name": "LGI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081915", "map_id": "none", "name": "Keratin filament formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081911", "map_id": "none", "name": "Keratin filament units", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LZF2", "map_id": "A0A3Q1LZF2", "name": "KRT34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074051", "map_id": "ENSBTAT00000074051", "name": "KRT34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M139", "map_id": "A0A3Q1M139", "name": "KRT33B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087011", "map_id": "ENSBTAT00000087011", "name": "KRT33B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MI98", "map_id": "F1MI98", "name": "KRT36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006440", "map_id": "ENSBTAT00000006440", "name": "KRT36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148I8", "map_id": "Q148I8", "name": "KRT31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018185", "map_id": "ENSBTAT00000018185", "name": "KRT31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPF8", "map_id": "A0A3Q1MPF8", "name": "KRT33A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072411", "map_id": "ENSBTAT00000072411", "name": "KRT33A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP90", "map_id": "A6QP90", "name": "KRT32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013107", "map_id": "ENSBTAT00000013107", "name": "KRT32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV22", "map_id": "A0A3Q1LV22", "name": "KRT38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076314", "map_id": "ENSBTAT00000076314", "name": "KRT38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3T1", "map_id": "F1N3T1", "name": "KRT39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026752", "map_id": "ENSBTAT00000026752", "name": "KRT39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWM2", "map_id": "A7YWM2", "name": "KRT40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023156", "map_id": "ENSBTAT00000023156", "name": "KRT40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0P5J4", "map_id": "Q0P5J4", "name": "KRT25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043116", "map_id": "ENSBTAT00000043116", "name": "KRT25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H712", "map_id": "A6H712", "name": "KRT26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043126", "map_id": "ENSBTAT00000043126", "name": "KRT26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M4F4", "map_id": "A0A3Q1M4F4", "name": "KRT12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071728", "map_id": "ENSBTAT00000071728", "name": "KRT12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6S1Q0", "map_id": "F6S1Q0", "name": "KRT18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001988", "map_id": "ENSBTAT00000001988", "name": "KRT18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LJB2", "map_id": "A0A3Q1LJB2", "name": "KRT13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083663", "map_id": "ENSBTAT00000083663", "name": "KRT13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08728", "map_id": "P08728", "name": "KRT19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006450", "map_id": "ENSBTAT00000006450", "name": "KRT19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7W8", "map_id": "G3X7W8", "name": "KRT16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047914", "map_id": "ENSBTAT00000047914", "name": "KRT16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFW9", "map_id": "F1MFW9", "name": "KRT24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027749", "map_id": "ENSBTAT00000027749", "name": "KRT24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MX98", "map_id": "G3MX98", "name": "KRT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064531", "map_id": "ENSBTAT00000064531", "name": "KRT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QL7", "map_id": "Q17QL7", "name": "KRT15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006445", "map_id": "ENSBTAT00000006445", "name": "KRT15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A3KMY1", "map_id": "A3KMY1", "name": "KRT82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009403", "map_id": "ENSBTAT00000009403", "name": "KRT82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N362", "map_id": "F1N362", "name": "KRT84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021519", "map_id": "ENSBTAT00000021519", "name": "KRT84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0W3", "map_id": "A0A3Q1M0W3", "name": "LOC787600", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077014", "map_id": "ENSBTAT00000077014", "name": "LOC787600", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI61", "map_id": "A0A452DI61", "name": "KRT83", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008857", "map_id": "ENSBTAT00000008857", "name": "KRT83", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B898", "map_id": "E1B898", "name": "KRT86", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018307", "map_id": "ENSBTAT00000018307", "name": "KRT86", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N566", "map_id": "F1N566", "name": "LOC507184", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038457", "map_id": "ENSBTAT00000038457", "name": "LOC507184", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148H4", "map_id": "Q148H4", "name": "KRT81", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038458", "map_id": "ENSBTAT00000038458", "name": "KRT81", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP32", "map_id": "A6QP32", "name": "KRT89", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038471", "map_id": "ENSBTAT00000038471", "name": "KRT89", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148H8", "map_id": "Q148H8", "name": "KRT72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010391", "map_id": "ENSBTAT00000010391", "name": "KRT72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWK3", "map_id": "A7YWK3", "name": "KRT73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010393", "map_id": "ENSBTAT00000010393", "name": "KRT73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFP2", "map_id": "A4IFP2", "name": "KRT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016832", "map_id": "ENSBTAT00000016832", "name": "KRT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDN1", "map_id": "A0A3Q1MDN1", "name": "KRT77", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067366", "map_id": "ENSBTAT00000067366", "name": "KRT77", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKE7", "map_id": "F1MKE7", "name": "KRT6C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057443", "map_id": "ENSBTAT00000057443", "name": "KRT6C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNX5", "map_id": "A6QNX5", "name": "KRT78", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000815", "map_id": "ENSBTAT00000000815", "name": "KRT78", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZ71", "map_id": "G3MZ71", "name": "KRT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063931", "map_id": "ENSBTAT00000063931", "name": "KRT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIJ6", "map_id": "A0A452DIJ6", "name": "KRT79", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016839", "map_id": "ENSBTAT00000016839", "name": "KRT79", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MYR8", "map_id": "A0A3Q1MYR8", "name": "KRT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072474", "map_id": "ENSBTAT00000072474", "name": "KRT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUY2", "map_id": "F1MUY2", "name": "KRT6B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046815", "map_id": "ENSBTAT00000046815", "name": "KRT6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "M0QVY0", "map_id": "M0QVY0", "name": "KRT6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000396", "map_id": "ENSBTAT00000000396", "name": "KRT6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081913", "map_id": "none", "name": "Keratin filament", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10081917", "map_id": "none", "name": "Keratin tetramers bind to form unit length filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081859", "map_id": "none", "name": "Keratin tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081909", "map_id": "none", "name": "Keratin unit length filament", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10081857", "map_id": "none", "name": "Keratin type I binds keratin type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081853", "map_id": "none", "name": "Keratin type II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081739", "map_id": "none", "name": "Keratin type I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081855", "map_id": "none", "name": "Keratin heterodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10081921", "map_id": "none", "name": "Formation of tonofilament bundles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081919", "map_id": "none", "name": "Keratin tonofilament", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10081861", "map_id": "none", "name": "Keratin type I/type II heterodimers form tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10082871", "map_id": "none", "name": "Formation of hair keratin fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10082865", "map_id": "none", "name": "Keratin associated proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3MYE1", "map_id": "G3MYE1", "name": "KRTAP3-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064142", "map_id": "ENSBTAT00000064142", "name": "KRTAP3-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MX57", "map_id": "G3MX57", "name": "LOC100294937", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065975", "map_id": "ENSBTAT00000065975", "name": "LOC100294937", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q24JX9", "map_id": "Q24JX9", "name": "KRTAP3-3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064111", "map_id": "ENSBTAT00000064111", "name": "KRTAP3-3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05B46", "map_id": "Q05B46", "name": "KRTAP11-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049339", "map_id": "ENSBTAT00000049339", "name": "KRTAP11-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MWP0", "map_id": "G3MWP0", "name": "LOC782628", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063461", "map_id": "ENSBTAT00000063461", "name": "LOC782628", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2U6", "map_id": "G3N2U6", "name": "KRTAP12-3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064310", "map_id": "ENSBTAT00000064310", "name": "KRTAP12-3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05B44", "map_id": "Q05B44", "name": "KRTAP12-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024766", "map_id": "ENSBTAT00000024766", "name": "KRTAP12-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8D5", "map_id": "A0A3Q1M8D5", "name": "KRTAP13-3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000066373", "map_id": "ENSBTAP00000066373", "name": "KRTAP13-3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9G9", "map_id": "E1B9G9", "name": "KRTAP13-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000053063", "map_id": "ENSBTAP00000053063", "name": "KRTAP13-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRY2", "map_id": "A0A3Q1LRY2", "name": "LOC112442670", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071483", "map_id": "ENSBTAT00000071483", "name": "LOC112442670", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0M4", "map_id": "A0A3Q1N0M4", "name": "LOC100848850", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069096", "map_id": "ENSBTAT00000069096", "name": "LOC100848850", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LY72", "map_id": "A0A3Q1LY72", "name": "KRTAP9-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083666", "map_id": "ENSBTAT00000083666", "name": "KRTAP9-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1L4", "map_id": "A0A3Q1N1L4", "name": "KRTAP9-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084386", "map_id": "ENSBTAT00000084386", "name": "KRTAP9-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0F6", "map_id": "A0A3Q1M0F6", "name": "KRTAP9-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAH7", "map_id": "E1BAH7", "name": "KRTAP9-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MWC2", "map_id": "A0A3Q1MWC2", "name": "LOC112442671", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068881", "map_id": "ENSBTAT00000068881", "name": "LOC112442671", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3V7", "map_id": "F1N3V7", "name": "LOC100138853", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043153", "map_id": "ENSBTAT00000043153", "name": "LOC100138853", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LK19", "map_id": "A0A3Q1LK19", "name": "KRTAP10-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087153", "map_id": "ENSBTAT00000087153", "name": "KRTAP10-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MEE6", "map_id": "A0A3Q1MEE6", "name": "KRTAP10-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNZ0", "map_id": "A0A3Q1LNZ0", "name": "KRTAP10-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP35", "map_id": "A6QP35", "name": "KRTAP10-8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043652", "map_id": "ENSBTAT00000043652", "name": "KRTAP10-8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LUM3", "map_id": "A0A3Q1LUM3", "name": "LOC616413", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068312", "map_id": "ENSBTAT00000068312", "name": "LOC616413", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6RZX2", "map_id": "F6RZX2", "name": "LOC100300014", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043662", "map_id": "ENSBTAT00000043662", "name": "LOC100300014", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LYD7", "map_id": "A0A3Q1LYD7", "name": "KRTAP10-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LUR9", "map_id": "A0A3Q1LUR9", "name": "KRTAP16-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071394", "map_id": "ENSBTAT00000071394", "name": "KRTAP16-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N073", "map_id": "G3N073", "name": "KRTAP24-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063306", "map_id": "ENSBTAT00000063306", "name": "KRTAP24-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPJ2", "map_id": "A0A3Q1LPJ2", "name": "LOC788284", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084954", "map_id": "ENSBTAT00000084954", "name": "LOC788284", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MLT3", "map_id": "A0A3Q1MLT3", "name": "LOC540285", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085549", "map_id": "ENSBTAT00000085549", "name": "LOC540285", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWJ9", "map_id": "A7YWJ9", "name": "KRTAP1-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043142", "map_id": "ENSBTAT00000043142", "name": "KRTAP1-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIW5", "map_id": "E1BIW5", "name": "LOC618495", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034860", "map_id": "ENSBTAT00000034860", "name": "LOC618495", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFR3", "map_id": "A0A3Q1MFR3", "name": "LOC787051", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075891", "map_id": "ENSBTAT00000075891", "name": "LOC787051", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NF50", "map_id": "A0A3Q1NF50", "name": "LOC100848572", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082065", "map_id": "ENSBTAT00000082065", "name": "LOC100848572", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MN32", "map_id": "A0A3Q1MN32", "name": "KRTAP4-11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084052", "map_id": "ENSBTAT00000084052", "name": "KRTAP4-11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7E345", "map_id": "A7E345", "name": "KRTAP4-7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043148", "map_id": "ENSBTAT00000043148", "name": "KRTAP4-7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LFA4", "map_id": "A0A3Q1LFA4", "name": "KRTAP4-11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N1W4", "map_id": "A0A3Q1N1W4", "name": "KRTAP4-11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMY6", "map_id": "E1BMY6", "name": "LOC100848612", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043146", "map_id": "ENSBTAT00000043146", "name": "LOC100848612", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQD4", "map_id": "A0A3Q1LQD4", "name": "KRTAP4-11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N892", "map_id": "A0A3Q1N892", "name": "KRTAP4-11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMY7", "map_id": "E1BMY7", "name": "LOC104968477", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043145", "map_id": "ENSBTAT00000043145", "name": "LOC104968477", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5Z5", "map_id": "A0A3Q1M5Z5", "name": "LOC788196", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078641", "map_id": "ENSBTAT00000078641", "name": "LOC788196", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSL9", "map_id": "A0A3Q1LSL9", "name": "KRTAP27-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080742", "map_id": "ENSBTAT00000080742", "name": "KRTAP27-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NHC3", "map_id": "A0A3Q1NHC3", "name": "LOC112446984", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072065", "map_id": "ENSBTAT00000072065", "name": "LOC112446984", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N3D2", "map_id": "A0A3Q1N3D2", "name": "LOC618359", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082261", "map_id": "ENSBTAT00000082261", "name": "LOC618359", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VC31", "map_id": "Q0VC31", "name": "LOC777598", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065867", "map_id": "ENSBTAT00000065867", "name": "LOC777598", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJJ0", "map_id": "A5PJJ0", "name": "LOC618938", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056985", "map_id": "ENSBTAT00000056985", "name": "LOC618938", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJJ4", "map_id": "A5PJJ4", "name": "LOC787225", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056308", "map_id": "ENSBTAT00000056308", "name": "LOC787225", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTA9", "map_id": "F1MTA9", "name": "KRTAP8-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000021000", "map_id": "ENSBTAP00000021000", "name": "KRTAP8-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N0A2", "map_id": "A0A3Q1N0A2", "name": "KRTAP19-5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075298", "map_id": "ENSBTAT00000075298", "name": "KRTAP19-5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082869", "map_id": "none", "name": "Keratin tonofilament:Keratin associated proteins polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050085", "map_id": "none", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050064", "map_id": "none", "name": "MEF2 proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1NNL3", "map_id": "A0A3Q1NNL3", "name": "phospho-MEF2D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079928", "map_id": "ENSBTAT00000079928", "name": "phospho-MEF2D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050074", "map_id": "none", "name": "phospho-p38 alpha/beta/gamma MAPK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LJZ7", "map_id": "A0A3Q1LJZ7", "name": "MAPK12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073649", "map_id": "ENSBTAT00000073649", "name": "MAPK12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050082", "map_id": "none", "name": "phospho p38:phospho MEF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10050116", "map_id": "none", "name": "Interaction of MyoD:E protein with MEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050080", "map_id": "none", "name": "phospho-MEF2 proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10050112", "map_id": "none", "name": "Myod:phospho-E heterodimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P17667", "map_id": "P17667", "name": "MYF5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038612", "map_id": "ENSBTAT00000038612", "name": "MYF5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7YS81", "map_id": "Q7YS81", "name": "MYOG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007923", "map_id": "ENSBTAT00000007923", "name": "MYOG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQN2", "map_id": "A0A3Q1LQN2", "name": "phospho-TCF3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071565", "map_id": "ENSBTAT00000071565", "name": "phospho-TCF3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050114", "map_id": "none", "name": "MyoD:phospho-E:phospho MEF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044090", "map_id": "none", "name": "Phosphorylated FOXO1A is excluded from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10042680", "map_id": "A0A452DJI7", "name": "phospho-FOXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044088", "map_id": "A0A452DJI7", "name": "phospho-FOXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071769", "map_id": "none", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071589", "map_id": "A0A3Q1M1S8", "name": "PMS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000082240", "map_id": "ENSBTAT00000082240", "name": "PMS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071585", "map_id": "F1MPG0", "name": "MLH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000022288", "map_id": "ENSBTAT00000022288", "name": "MLH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071591", "map_id": "none", "name": "MLH1:PMS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MPG0", "map_id": "F1MPG0", "name": "MLH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1S8", "map_id": "A0A3Q1M1S8", "name": "PMS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071640", "map_id": "none", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071626", "map_id": "none", "name": "MSH2:MSH6:ADP:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3MHE4", "map_id": "Q3MHE4", "name": "MSH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003556", "map_id": "ENSBTAT00000003556", "name": "MSH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9Q4", "map_id": "E1B9Q4", "name": "MSH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001867", "map_id": "ENSBTAT00000001867", "name": "MSH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071603", "map_id": "none", "name": "MSH2:MSH6:ATP:DNA containing 1-2 base mismatch", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071628", "map_id": "none", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358514", "map_id": "none", "name": "DNA containing mismatch or 1-2 base IDL", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071624", "map_id": "none", "name": "MSH2:MSH6:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071630", "map_id": "none", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358610", "map_id": "none", "name": "DNA containing single strand nick (5' phosphate, 3' hydroxyl)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_109966", "map_id": "none", "name": "Repaired double-stranded DNA", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_164121", "map_id": "CHEBI:16027", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10033501", "map_id": "A0A3S5ZPU0", "name": "LIG1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000031920", "map_id": "ENSBTAT00000031920", "name": "LIG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071767", "map_id": "none", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071599", "map_id": "E1B9Q4", "name": "MSH6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071595", "map_id": "Q3MHE4", "name": "MSH2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10071607", "map_id": "none", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071605", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071622", "map_id": "none", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071619", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071638", "map_id": "none", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071634", "map_id": "E1BF15", "name": "EXO1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000012365", "map_id": "ENSBTAT00000012365", "name": "EXO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071636", "map_id": "none", "name": "EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BF15", "map_id": "E1BF15", "name": "EXO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071617", "map_id": "none", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358527", "map_id": "none", "name": "DNA containing IDL of 2 or more bases", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071613", "map_id": "none", "name": "MSH2:MSH3:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LUI6", "map_id": "A0A3Q1LUI6", "name": "MSH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076740", "map_id": "ENSBTAT00000076740", "name": "MSH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071615", "map_id": "none", "name": "MSH2:MSH3:ADP:DNA containing IDL of 2 bases or more", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071765", "map_id": "none", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071611", "map_id": "A0A3Q1LUI6", "name": "MSH3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10047196", "map_id": "none", "name": "Calcium Binds Troponin-C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047192", "map_id": "none", "name": "Inactive Sarcomere Protein Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M4Y0", "map_id": "A0A3Q1M4Y0", "name": "MYBPC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082241", "map_id": "ENSBTAT00000082241", "name": "MYBPC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQC6", "map_id": "A0A3Q1LQC6", "name": "MYBPC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076718", "map_id": "ENSBTAT00000076718", "name": "MYBPC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QP89", "map_id": "A6QP89", "name": "MYBPC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043649", "map_id": "ENSBTAT00000043649", "name": "MYBPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QPA6", "map_id": "A6QPA6", "name": "MYH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001120", "map_id": "ENSBTAT00000001120", "name": "MYH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2G0", "map_id": "F1N2G0", "name": "MYH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007359", "map_id": "ENSBTAT00000007359", "name": "MYH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LVZ9", "map_id": "A0A3Q1LVZ9", "name": "MYH8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085880", "map_id": "ENSBTAT00000085880", "name": "MYH8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0JNJ5", "map_id": "A0JNJ5", "name": "MYL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000054271", "map_id": "ENSBTAT00000054271", "name": "MYL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M165", "map_id": "A0A3Q1M165", "name": "MYL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075504", "map_id": "ENSBTAT00000075504", "name": "MYL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1RMM7", "map_id": "Q1RMM7", "name": "MYL4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057007", "map_id": "ENSBTAT00000057007", "name": "MYL4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O62654", "map_id": "O62654", "name": "DES", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007041", "map_id": "ENSBTAT00000007041", "name": "DES", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6T8D8", "map_id": "Q6T8D8", "name": "TCAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015579", "map_id": "ENSBTAT00000015579", "name": "TCAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48616", "map_id": "P48616", "name": "VIM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024572", "map_id": "ENSBTAT00000024572", "name": "VIM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MC60", "map_id": "A0A3Q1MC60", "name": "NEB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086078", "map_id": "ENSBTAT00000086078", "name": "NEB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5KR48", "map_id": "Q5KR48", "name": "TPM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046179", "map_id": "ENSBTAT00000046179", "name": "TPM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68138", "map_id": "P68138", "name": "ACTA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006534", "map_id": "ENSBTAT00000006534", "name": "ACTA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWR2", "map_id": "A0A3Q1LWR2", "name": "DMD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083316", "map_id": "ENSBTAT00000083316", "name": "DMD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6QIC1", "map_id": "F6QIC1", "name": "TNNI2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014452", "map_id": "ENSBTAT00000014452", "name": "TNNI2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MYN5", "map_id": "G3MYN5", "name": "TNNI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063025", "map_id": "ENSBTAT00000063025", "name": "TNNI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N264", "map_id": "G3N264", "name": "TNNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065361", "map_id": "ENSBTAT00000065361", "name": "TNNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047194", "map_id": "none", "name": "Calcium Bound Sarcomere Protein Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047198", "map_id": "none", "name": "Release Of ADP From Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047181", "map_id": "none", "name": "ADP:Calcium Bound Sarcomere Protein Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047200", "map_id": "none", "name": "Myosin Binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047177", "map_id": "none", "name": "ATP:Calcium Bound Sarcomere Protein Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10047186", "map_id": "none", "name": "ATP Hydrolysis By Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047183", "map_id": "none", "name": "Myosin Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10071824", "map_id": "none", "name": "KCNH2:KCNE transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071821", "map_id": "none", "name": "KCNH2:KCNE", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LSF6", "map_id": "A0A3Q1LSF6", "name": "KCNH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067149", "map_id": "ENSBTAT00000067149", "name": "KCNH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077468", "map_id": "none", "name": "NPPA(124-151) binds NPR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10071836", "map_id": "P07501", "name": "NPPA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000008819", "map_id": "ENSBTAT00000008819", "name": "NPPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077464", "map_id": "none", "name": "NPR1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BN71", "map_id": "E1BN71", "name": "NPR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008184", "map_id": "ENSBTAT00000008184", "name": "NPR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077466", "map_id": "none", "name": "NPPA(124-151):NPR1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P07501", "map_id": "P07501", "name": "NPPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071843", "map_id": "none", "name": "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071828", "map_id": "P07501", "name": "NPPA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071830", "map_id": "P07501", "name": "NPPA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071834", "map_id": "P07501", "name": "NPPA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071832", "map_id": "P07501", "name": "NPPA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071840", "map_id": "A0A3Q1LLW8", "name": "CORIN", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000085692", "map_id": "ENSBTAT00000085692", "name": "CORIN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071819", "map_id": "none", "name": "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071816", "map_id": "none", "name": "KCND tetramer:KCNIP tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MY95", "map_id": "F1MY95", "name": "KCND3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044879", "map_id": "ENSBTAT00000044879", "name": "KCND3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q52PG9", "map_id": "Q52PG9", "name": "KCND1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011882", "map_id": "ENSBTAT00000011882", "name": "KCND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MVI5", "map_id": "F1MVI5", "name": "KCND2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045500", "map_id": "ENSBTAT00000045500", "name": "KCND2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LV43", "map_id": "A0A3Q1LV43", "name": "KCNIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072593", "map_id": "ENSBTAT00000072593", "name": "KCNIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5I5", "map_id": "A0A3Q1M5I5", "name": "KCNIP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066696", "map_id": "ENSBTAT00000066696", "name": "KCNIP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053180", "map_id": "none", "name": "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10053175", "map_id": "none", "name": "ATP1A:ATP1B:FXYD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T0C6", "map_id": "Q3T0C6", "name": "ATP1B3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018795", "map_id": "ENSBTAT00000018795", "name": "ATP1B3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLL5", "map_id": "A6QLL5", "name": "ATP1B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018181", "map_id": "ENSBTAT00000018181", "name": "ATP1B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDL6", "map_id": "A2VDL6", "name": "ATP1A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049161", "map_id": "ENSBTAT00000049161", "name": "ATP1A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8N5", "map_id": "E1B8N5", "name": "ATP1A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013951", "map_id": "ENSBTAT00000013951", "name": "ATP1A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MJB8", "map_id": "A0A3Q1MJB8", "name": "FXYD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077228", "map_id": "ENSBTAT00000077228", "name": "FXYD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWV7", "map_id": "A0A3Q1LWV7", "name": "FXYD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073582", "map_id": "ENSBTAT00000073582", "name": "FXYD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10053178", "map_id": "none", "name": "ATP1A:ATP1B:FXYD:cardiac glycosides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091759", "map_id": "none", "name": "ATP1A:ATP1B:FXYD binds cardiac glycosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9684063", "map_id": "none", "name": "cardiac glycosides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10048787", "map_id": "none", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_111875", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10048770", "map_id": "A0A3Q1M9U0", "name": "ATP2A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000078158", "map_id": "ENSBTAT00000078158", "name": "ATP2A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048785", "map_id": "none", "name": "CAMK2 heteromer:CALM:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047893", "map_id": "none", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10047890", "map_id": "A0A3Q1ND98", "name": "ATP2B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000077323", "map_id": "ENSBTAT00000077323", "name": "ATP2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071876", "map_id": "none", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071873", "map_id": "none", "name": "KCNK dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BEH3", "map_id": "E1BEH3", "name": "KCNK15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004382", "map_id": "ENSBTAT00000004382", "name": "KCNK15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT89", "map_id": "A0A3Q1MT89", "name": "KCNK3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075452", "map_id": "ENSBTAT00000075452", "name": "KCNK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0P5A0", "map_id": "Q0P5A0", "name": "KCNK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005929", "map_id": "ENSBTAT00000005929", "name": "KCNK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX91", "map_id": "F1MX91", "name": "KCNK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032182", "map_id": "ENSBTAT00000032182", "name": "KCNK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035579", "map_id": "none", "name": "RDH10,11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10035564", "map_id": "none", "name": "RLBP1:11cROL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P10123", "map_id": "P10123", "name": "RLBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047900", "map_id": "ENSBTAT00000047900", "name": "RLBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2473611", "map_id": "CHEBI:16302", "name": "11cROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035566", "map_id": "none", "name": "RLBP1:11cRAL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10035576", "map_id": "none", "name": "RDH10,11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10065597", "map_id": "none", "name": "RDH5 oxidises 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10065594", "map_id": "none", "name": "RDH5(1-318)-like Proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10065644", "map_id": "none", "name": "11cROL binds to RLBP1 to form RLBP1:11cROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035562", "map_id": "P10123", "name": "RLBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035406", "map_id": "none", "name": "Photons induce isomerization of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane" }, { "id": "species_10035401", "map_id": "P02699", "name": "RHO", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10035404", "map_id": "P02699", "name": "RHO", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10065646", "map_id": "none", "name": "RBP3 regulates the transport of atROL from ROS to RPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2473615", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2473604", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065601", "map_id": "F1MLW4", "name": "RBP3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000006585", "map_id": "ENSBTAT00000006585", "name": "RBP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088914", "map_id": "none", "name": "RLBP1:11cRAL dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8960974", "map_id": "CHEBI:16066", "name": "11cRAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065604", "map_id": "none", "name": "RBP3 transports 11cRAL to rod photoreceptor outer segment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10077751", "map_id": "none", "name": "CYP4V2 omega-hydroxylates DHA to HDoHE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6786220", "map_id": "CHEBI:36005", "name": "DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6786225", "map_id": "CHEBI:72790", "name": "hydroxydocosahexaenoic acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10077748", "map_id": "F1N3Z7", "name": "CYP4V2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000085962", "map_id": "ENSBTAT00000085962", "name": "CYP4V2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035558", "map_id": "none", "name": "atROL binds RBP1 to form RBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035556", "map_id": "none", "name": "RBP1:atROL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065606", "map_id": "none", "name": "11cRAL binds to opsin to form 11c-retinyl:RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2565923", "map_id": "P02699", "name": "Rho", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10049433", "map_id": "none", "name": "ZIP6 and ZIP14 mediate zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049430", "map_id": "G3MYG6", "name": "SLC39A6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065246", "map_id": "ENSBTAT00000065246", "name": "SLC39A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049464", "map_id": "none", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049461", "map_id": "none", "name": "SLC39A1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3SYU3", "map_id": "Q3SYU3", "name": "SLC39A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034015", "map_id": "ENSBTAT00000034015", "name": "SLC39A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEU4", "map_id": "E1BEU4", "name": "SLC39A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001238", "map_id": "ENSBTAT00000001238", "name": "SLC39A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWM2", "map_id": "A0A3Q1LWM2", "name": "SLC39A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075196", "map_id": "ENSBTAT00000075196", "name": "SLC39A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049440", "map_id": "none", "name": "ZIP8 mediates zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049437", "map_id": "E1BQ28", "name": "SLC39A8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000007448", "map_id": "ENSBTAT00000007448", "name": "SLC39A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049447", "map_id": "none", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_442320", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10049444", "map_id": "Q0P5C9", "name": "SLC39A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000010771", "map_id": "ENSBTAT00000010771", "name": "SLC39A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071469", "map_id": "none", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071466", "map_id": "A6QR45", "name": "MRS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000006554", "map_id": "ENSBTAT00000006554", "name": "MRS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070735", "map_id": "none", "name": "ANKH transports PPi from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113542", "map_id": "CHEBI:29888", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10070732", "map_id": "F1MAW1", "name": "ANKH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000017818", "map_id": "ENSBTAT00000017818", "name": "ANKH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071280", "map_id": "none", "name": "AZGP1 binds PIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10071266", "map_id": "A0A452DK44", "name": "AZGP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000037204", "map_id": "ENSBTAT00000037204", "name": "AZGP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071276", "map_id": "none", "name": "Homologues of PIP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MCV8", "map_id": "F1MCV8", "name": "PIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008743", "map_id": "ENSBTAT00000008743", "name": "PIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N598", "map_id": "A0A3Q1N598", "name": "LOC104972276", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079328", "map_id": "ENSBTAT00000079328", "name": "LOC104972276", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071278", "map_id": "none", "name": "AZGP1:PIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A452DK44", "map_id": "A0A452DK44", "name": "AZGP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071490", "map_id": "none", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114632", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071487", "map_id": "G3MY77", "name": "MAGT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10087365", "map_id": "none", "name": "VRAC heteromer transports I-, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8941540", "map_id": "none", "name": "I-, Cl-", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_209785", "map_id": "CHEBI:16382", "name": "I-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8941541", "map_id": "none", "name": "I-, Cl-", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10087362", "map_id": "none", "name": "VRAC heteromer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4IFE5", "map_id": "A4IFE5", "name": "LRRC8D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027912", "map_id": "ENSBTAT00000027912", "name": "LRRC8D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E42", "map_id": "Q08E42", "name": "LRRC8A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084512", "map_id": "ENSBTAT00000084512", "name": "LRRC8A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6PRJ0", "map_id": "F6PRJ0", "name": "LRRC8E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005636", "map_id": "ENSBTAT00000005636", "name": "LRRC8E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PK13", "map_id": "A5PK13", "name": "LRRC8C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085971", "map_id": "ENSBTAT00000085971", "name": "LRRC8C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071476", "map_id": "none", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071473", "map_id": "F1MFE0", "name": "TUSC3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000012110", "map_id": "ENSBTAT00000012110", "name": "TUSC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086343", "map_id": "none", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932838", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_8932842", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10086340", "map_id": "F1MII2", "name": "SLC66A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "ENSBTAT00000018143", "map_id": "ENSBTAT00000018143", "name": "SLC66A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071462", "map_id": "none", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071459", "map_id": "none", "name": "NIPAs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N136", "map_id": "F1N136", "name": "NIPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002985", "map_id": "ENSBTAT00000002985", "name": "NIPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047930", "map_id": "none", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30991", "map_id": "CHEBI:16356", "name": "cGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113578", "map_id": "CHEBI:17345", "name": "GMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10047927", "map_id": "none", "name": "cGMP phosphodiesterases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N569", "map_id": "A0A3Q1N569", "name": "PDE9A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072103", "map_id": "ENSBTAT00000072103", "name": "PDE9A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065369", "map_id": "none", "name": "NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395852", "map_id": "CHEBI:63220", "name": "8-oxo-dGTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395817", "map_id": "CHEBI:63223", "name": "8-oxo-dGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065366", "map_id": "E1B7T3", "name": "NUDT15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025978", "map_id": "ENSBTAT00000025978", "name": "NUDT15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065371", "map_id": "none", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395868", "map_id": "CHEBI:65119", "name": "2-hydroxy-ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395878", "map_id": "CHEBI:65129", "name": "2-hydroxy-AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065356", "map_id": "none", "name": "NUDT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MLL8", "map_id": "F1MLL8", "name": "NUDT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003218", "map_id": "ENSBTAT00000003218", "name": "NUDT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065386", "map_id": "none", "name": "NUDT18 hydrolyses 8-OH-dADP to 8-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395963", "map_id": "CHEBI:70963", "name": "8-hydroxy-dADP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395964", "map_id": "CHEBI:70964", "name": "8-hydroxy-dAMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065375", "map_id": "F1N0N5", "name": "NUDT18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000004527", "map_id": "ENSBTAT00000004527", "name": "NUDT18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065359", "map_id": "none", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395822", "map_id": "CHEBI:63208", "name": "2-hydroxy-dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395855", "map_id": "CHEBI:63211", "name": "2-hydroxy-dAMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065760", "map_id": "none", "name": "NUDT16 hydrolyses dIDP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2509796", "map_id": "CHEBI:28823", "name": "dIDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2509805", "map_id": "CHEBI:28806", "name": "dIMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10065757", "map_id": "none", "name": "NUDT16 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A1A4Q9", "map_id": "A1A4Q9", "name": "NUDT16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053197", "map_id": "ENSBTAT00000053197", "name": "NUDT16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2509819", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10065328", "map_id": "none", "name": "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2393945", "map_id": "CHEBI:16960", "name": "ADP-Rib", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2393950", "map_id": "CHEBI:17797", "name": "R5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10065325", "map_id": "none", "name": "NUDT9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A7MBI8", "map_id": "A7MBI8", "name": "NUDT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015090", "map_id": "ENSBTAT00000015090", "name": "NUDT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065763", "map_id": "none", "name": "NUDT16 hydrolyses IDP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2509811", "map_id": "CHEBI:17808", "name": "IDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_2509792", "map_id": "CHEBI:17202", "name": "IMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10065362", "map_id": "none", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10065378", "map_id": "none", "name": "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395880", "map_id": "CHEBI:65134", "name": "8-oxo-GDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2395877", "map_id": "CHEBI:65135", "name": "8-oxo-GMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065381", "map_id": "none", "name": "NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2395883", "map_id": "CHEBI:63728", "name": "8-oxo-dGDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065383", "map_id": "none", "name": "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10065319", "map_id": "none", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1131972", "map_id": "CHEBI:16960", "name": "ADP-D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065316", "map_id": "none", "name": "NUDT5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MMR8", "map_id": "F1MMR8", "name": "NUDT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068724", "map_id": "ENSBTAT00000068724", "name": "NUDT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072489", "map_id": "none", "name": "UNC119B binds myristoylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072485", "map_id": "E1BP93", "name": "NPHP3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000007584", "map_id": "ENSBTAT00000007584", "name": "NPHP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072480", "map_id": "E1BIZ3", "name": "UNC119B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009843", "map_id": "ENSBTAT00000009843", "name": "UNC119B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072487", "map_id": "none", "name": "UNC119B:myristoylated ciliary cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BIZ3", "map_id": "E1BIZ3", "name": "UNC119B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BP93", "map_id": "E1BP93", "name": "NPHP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072497", "map_id": "none", "name": "UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_18730", "compartment_display": "cilium" }, { "id": "species_10072495", "map_id": "none", "name": "UNC119B:myristoylated ciliary cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_18730", "compartment_display": "cilium", "complex": "true" }, { "id": "reaction_10033379", "map_id": "none", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10033367", "map_id": "A0A3Q1MVB0", "name": "CDC6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000083861", "map_id": "ENSBTAT00000083861", "name": "phospho-CDC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033377", "map_id": "none", "name": "E2F1/2/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BG94", "map_id": "E1BG94", "name": "E2F1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005182", "map_id": "ENSBTAT00000005182", "name": "E2F1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BD75", "map_id": "E1BD75", "name": "E2F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023554", "map_id": "ENSBTAT00000023554", "name": "E2F2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033412", "map_id": "none", "name": "The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033390", "map_id": "none", "name": "Cdt1:geminin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q56JZ0", "map_id": "Q56JZ0", "name": "GMNN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023040", "map_id": "ENSBTAT00000023040", "name": "GMNN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LIW5", "map_id": "A0A3Q1LIW5", "name": "CDT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067336", "map_id": "ENSBTAT00000067336", "name": "CDT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033410", "map_id": "none", "name": "geminin:ubiquitin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10033388", "map_id": "A0A3Q1LIW5", "name": "CDT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10085788", "map_id": "none", "name": "PCTP binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1524163", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10085786", "map_id": "none", "name": "PCTP:PC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P02720", "map_id": "P02720", "name": "PCTP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086064", "map_id": "none", "name": "STARD7 binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10086060", "map_id": "A0A3Q1LZP9", "name": "STARD7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000071992", "map_id": "ENSBTAT00000071992", "name": "STARD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086062", "map_id": "none", "name": "STARD7:PC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LZP9", "map_id": "A0A3Q1LZP9", "name": "STARD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085808", "map_id": "none", "name": "STARD10 binds LPCAT1 and PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035781", "map_id": "F1MTK4", "name": "LPCAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10085792", "map_id": "A0A3Q1MRL1", "name": "STARD10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000071421", "map_id": "ENSBTAT00000071421", "name": "STARD10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085794", "map_id": "none", "name": "STARD10:LPCAT1:PC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MRL1", "map_id": "A0A3Q1MRL1", "name": "STARD10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085024", "map_id": "none", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8865642", "map_id": "CHEBI:64567", "name": "LPC (22:6)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8865629", "map_id": "CHEBI:64567", "name": "LPC (22:6)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10085021", "map_id": "A6QQA1", "name": "MFSD2A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000017353", "map_id": "ENSBTAT00000017353", "name": "MFSD2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059141", "map_id": "none", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500596", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10059138", "map_id": "none", "name": "LPIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BLQ9", "map_id": "E1BLQ9", "name": "LPIN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012081", "map_id": "ENSBTAT00000012081", "name": "LPIN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059063", "map_id": "none", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10059060", "map_id": "none", "name": "CHK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LRY5", "map_id": "A0A3Q1LRY5", "name": "CHKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082323", "map_id": "ENSBTAT00000082323", "name": "CHKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPV1", "map_id": "A0A3Q1MPV1", "name": "CHKB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074052", "map_id": "ENSBTAT00000074052", "name": "CHKB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085798", "map_id": "none", "name": "STARD10 transports PC from ER membrane to lamellar body membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085796", "map_id": "none", "name": "STARD10:PC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2133233", "compartment_display": "lamellar body membrane", "complex": "true" }, { "id": "reaction_10059094", "map_id": "none", "name": "PCho is dephosphorylated to Cho by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10059079", "map_id": "none", "name": "PHOSPHO1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BCN8", "map_id": "E1BCN8", "name": "PHOSPHO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000037", "map_id": "ENSBTAT00000000037", "name": "PHOSPHO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090489", "map_id": "none", "name": "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025001", "map_id": "CHEBI:132228", "name": "13(S),14(S)-epoxy-DHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9026761", "map_id": "CHEBI:138202", "name": "MCTR1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090486", "map_id": "none", "name": "LTC4S trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2NKS0", "map_id": "Q2NKS0", "name": "LTC4S", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012836", "map_id": "ENSBTAT00000012836", "name": "LTC4S", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090480", "map_id": "none", "name": "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039964", "map_id": "none", "name": "GSTM2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MUX5", "map_id": "F1MUX5", "name": "LOC100295687", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016866", "map_id": "ENSBTAT00000016866", "name": "LOC100295687", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LY34", "map_id": "A0A3Q1LY34", "name": "GSTM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075425", "map_id": "ENSBTAT00000075425", "name": "GSTM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090491", "map_id": "none", "name": "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024768", "map_id": "CHEBI:138646", "name": "7S(8)-epoxy-17(S)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9026915", "map_id": "CHEBI:140268", "name": "RCTR1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044835", "map_id": "none", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353560", "map_id": "CHEBI:15746", "name": "SPN", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_353575", "map_id": "CHEBI:17312", "name": "NASPN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044832", "map_id": "Q3T0Q0", "name": "SAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023087", "map_id": "ENSBTAT00000023087", "name": "SAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044837", "map_id": "none", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353555", "map_id": "CHEBI:17927", "name": "NASPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10076360", "map_id": "none", "name": "DUOX1,2 reduce O2 to H2O2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_351627", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351628", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076357", "map_id": "none", "name": "DUOX1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BMK1", "map_id": "E1BMK1", "name": "DUOX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021618", "map_id": "ENSBTAT00000021618", "name": "DUOX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMS3", "map_id": "E1BMS3", "name": "DUOX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021603", "map_id": "ENSBTAT00000021603", "name": "DUOX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043978", "map_id": "none", "name": "Iodide is taken up by thyroid epithelial cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_209818", "map_id": "CHEBI:16382", "name": "I-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10043975", "map_id": "F1MT46", "name": "SLC5A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021031", "map_id": "ENSBTAT00000021031", "name": "SLC5A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044828", "map_id": "none", "name": "Iodide is organified", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_351630", "map_id": "CHEBI:17606", "name": "I2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10043921", "map_id": "A0A3Q1M790", "name": "TPO", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071301", "map_id": "ENSBTAT00000071301", "name": "TPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043980", "map_id": "none", "name": "DIT and MIT combine to form triiodothyronine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_352329", "map_id": "CHEBI:15768", "name": "DIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351639", "map_id": "CHEBI:27847", "name": "MIT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352331", "map_id": "CHEBI:28774", "name": "T3", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10043986", "map_id": "none", "name": "Tyrosine is diiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10043924", "map_id": "none", "name": "Tyrosine is monoiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_622410", "map_id": "CHEBI:43451", "name": "HI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10043956", "map_id": "none", "name": "Two DITs combine to form thyroxine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_352326", "map_id": "CHEBI:18332", "name": "T4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10066745", "map_id": "none", "name": "NOC2L binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066741", "map_id": "Q3SYU1", "name": "NOC2L", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000021980", "map_id": "ENSBTAT00000021980", "name": "NOC2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066743", "map_id": "none", "name": "NOC2L:p-S15,S20-TP53", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3SYU1", "map_id": "Q3SYU1", "name": "NOC2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066712", "map_id": "none", "name": "NUAK1 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066701", "map_id": "none", "name": "TP53 Tetramer:STK11:p-T211-NUAK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B9B6", "map_id": "E1B9B6", "name": "phospho-NUAK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013805", "map_id": "ENSBTAT00000013805", "name": "phospho-NUAK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCU9", "map_id": "E1BCU9", "name": "STK11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015459", "map_id": "ENSBTAT00000015459", "name": "STK11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066709", "map_id": "none", "name": "p-S15,S392-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066690", "map_id": "E1BCU9", "name": "STK11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066699", "map_id": "E1B9B6", "name": "phospho-NUAK1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10081563", "map_id": "none", "name": "TP53 binds STK11 and NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066694", "map_id": "E1B9B6", "name": "NUAK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066696", "map_id": "none", "name": "TP53 Tetramer:STK11:NUAK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10081595", "map_id": "none", "name": "CDK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081585", "map_id": "none", "name": "p-S15,S33,S46-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10081592", "map_id": "none", "name": "p-Y15,S159-CDK5:CDK5R1 (99-307)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10080730", "map_id": "none", "name": "TP53 binds HIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10080726", "map_id": "E1BQ34", "name": "HIPK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000015051", "map_id": "ENSBTAT00000015051", "name": "HIPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080728", "map_id": "none", "name": "TP53 Tetramer:HIPK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BQ34", "map_id": "E1BQ34", "name": "HIPK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081629", "map_id": "none", "name": "TP53RK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081626", "map_id": "A5PK80", "name": "TP53RK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000039179", "map_id": "ENSBTAT00000039179", "name": "TP53RK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066704", "map_id": "none", "name": "STK11 (LKB1) phosphorylates NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10080722", "map_id": "none", "name": "HIPK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066668", "map_id": "none", "name": "TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MHM3", "map_id": "A0A3Q1MHM3", "name": "phospho-HIPK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072457", "map_id": "ENSBTAT00000072457", "name": "phospho-HIPK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBC1", "map_id": "A0A3Q1MBC1", "name": "TP53INP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084811", "map_id": "ENSBTAT00000084811", "name": "TP53INP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066659", "map_id": "A0A3Q1MBC1", "name": "TP53INP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066666", "map_id": "none", "name": "p-HIPK2:PIN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10078728", "map_id": "none", "name": "p-S15,S20,S46-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066870", "map_id": "none", "name": "MAPKAPK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066862", "map_id": "none", "name": "p-S37-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066867", "map_id": "none", "name": "phospho-p38 MAPK:p-T-182-MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10081622", "map_id": "none", "name": "AMPK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081619", "map_id": "none", "name": "Activated AMPK heterotrimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10078731", "map_id": "none", "name": "DYRK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10078718", "map_id": "E1BG90", "name": "phospho-DYRK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000009545", "map_id": "ENSBTAT00000009545", "name": "DYRK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066670", "map_id": "none", "name": "TP53INP1 and HIPK2 bind TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10078720", "map_id": "none", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10078714", "map_id": "E1BG90", "name": "DYRK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10081602", "map_id": "none", "name": "PLK3 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081599", "map_id": "Q0VCE7", "name": "PLK3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000008055", "map_id": "ENSBTAT00000008055", "name": "PLK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039801", "map_id": "none", "name": "Association of Emi1 with Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10038468", "map_id": "A0A3Q1M5V7", "name": "FBXO5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000083057", "map_id": "ENSBTAT00000083057", "name": "FBXO5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039797", "map_id": "none", "name": "Cdh1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q32L05", "map_id": "Q32L05", "name": "phospho-FZR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074490", "map_id": "ENSBTAT00000074490", "name": "phospho-FZR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039799", "map_id": "none", "name": "Emi1:Cdh1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M5V7", "map_id": "A0A3Q1M5V7", "name": "FBXO5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039852", "map_id": "none", "name": "Association of Emi1 with Cdc20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10039803", "map_id": "F1MRW5", "name": "CDC20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10039850", "map_id": "none", "name": "Emi1:Cdc20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10038033", "map_id": "none", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038023", "map_id": "F1MRW5", "name": "CDC20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10038027", "map_id": "G3MX31", "name": "MAD2L1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000065027", "map_id": "ENSBTAT00000065027", "name": "MAD2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038031", "map_id": "none", "name": "MAD2*CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3MX31", "map_id": "G3MX31", "name": "MAD2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038035", "map_id": "none", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038019", "map_id": "Q1JQB2", "name": "BUB3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000057027", "map_id": "ENSBTAT00000057027", "name": "BUB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038015", "map_id": "F1MWP1", "name": "BUB1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009521", "map_id": "ENSBTAT00000009521", "name": "BUB1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038029", "map_id": "none", "name": "hBUBR1:hBUB3:MAD2*:CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MWP1", "map_id": "F1MWP1", "name": "BUB1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQB2", "map_id": "Q1JQB2", "name": "BUB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033833", "map_id": "none", "name": "urocanate + H2O => 4-imidazolone-5-propionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30721", "map_id": "CHEBI:30817", "name": "UCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_34979", "map_id": "CHEBI:27384", "name": "4I-5PROA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033830", "map_id": "none", "name": "UROC1:NAD+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LXH7", "map_id": "A0A3Q1LXH7", "name": "UROC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083727", "map_id": "ENSBTAT00000083727", "name": "UROC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033849", "map_id": "none", "name": "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30158", "map_id": "CHEBI:18327", "name": "NF-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_70919", "map_id": "CHEBI:15639", "name": "FITHF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033846", "map_id": "none", "name": "FTCD octamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MBB6", "map_id": "A0A3Q1MBB6", "name": "FTCD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074746", "map_id": "ENSBTAT00000074746", "name": "FTCD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054585", "map_id": "none", "name": "Histidine is decarboxylated to histamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_175992", "map_id": "CHEBI:18295", "name": "Hist", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10054582", "map_id": "none", "name": "PXLP-K305-HDC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q5EA83", "map_id": "Q5EA83", "name": "HDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013083", "map_id": "ENSBTAT00000013083", "name": "HDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077758", "map_id": "none", "name": "CARNS1 transforms ATP, L-His, b-Ala to CARN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6786250", "map_id": "CHEBI:15727", "name": "CARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077755", "map_id": "F1MY45", "name": "CARNS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023529", "map_id": "ENSBTAT00000023529", "name": "CARNS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086033", "map_id": "none", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8876775", "map_id": "CHEBI:18323", "name": "Anserine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086030", "map_id": "E1BJC0", "name": "CARNMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000010790", "map_id": "ENSBTAT00000010790", "name": "CARNMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033840", "map_id": "none", "name": "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033837", "map_id": "A5PJV3", "name": "AMDHD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000021647", "map_id": "ENSBTAT00000021647", "name": "AMDHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059066", "map_id": "none", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524042", "map_id": "CHEBI:17517", "name": "PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524064", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524072", "map_id": "CHEBI:28494", "name": "cardiolipin", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524067", "map_id": "CHEBI:17361", "name": "cytidine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10058823", "map_id": "A5PJS7", "name": "CRLS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000000072", "map_id": "ENSBTAT00000000072", "name": "CRLS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10092237", "map_id": "none", "name": "Hemes bind to BACH1:MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9707575", "map_id": "none", "name": "Hemes", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10092233", "map_id": "none", "name": "BACH1:MAFK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BB01", "map_id": "E1BB01", "name": "MAFK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025702", "map_id": "ENSBTAT00000025702", "name": "MAFK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJL3", "map_id": "E1BJL3", "name": "BACH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005416", "map_id": "ENSBTAT00000005416", "name": "BACH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055987", "map_id": "E1BB01", "name": "MAFK", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10092235", "map_id": "none", "name": "BACH1:Hemes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092269", "map_id": "none", "name": "XPO1:BACH1:Hemes are transported out of the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092259", "map_id": "none", "name": "XPO1:BACH1:Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BE98", "map_id": "E1BE98", "name": "XPO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092267", "map_id": "none", "name": "XPO1:BACH1:Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10092239", "map_id": "none", "name": "BACH1 binds MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10092231", "map_id": "E1BJL3", "name": "BACH1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10092271", "map_id": "none", "name": "XPO1 (CRM1) binds to BACH1:Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10092225", "map_id": "none", "name": "Hemes bind to CLEC1B dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9707310", "map_id": "none", "name": "Hemes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_71185", "map_id": "CHEBI:17627", "name": "heme", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10092221", "map_id": "none", "name": "CLEC1B dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BLL1", "map_id": "E1BLL1", "name": "CLEC1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053034", "map_id": "ENSBTAT00000053034", "name": "CLEC1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092223", "map_id": "none", "name": "CLEC1B dimer:Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10092227", "map_id": "none", "name": "FeHM dissociates from MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064743", "map_id": "none", "name": "MetHb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "P01966", "map_id": "P01966", "name": "HBA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037545", "map_id": "ENSBTAT00000037545", "name": "HBA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_917955", "map_id": "CHEBI:36144", "name": "FeHM", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10064749", "map_id": "none", "name": "ApoHb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10052914", "map_id": "none", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9707308", "map_id": "none", "name": "Hemes", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10092214", "map_id": "none", "name": "H2O2 oxidises ferrohemoglobin to MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10092210", "map_id": "none", "name": "ferrohemoglobin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_9707624", "map_id": "CHEBI:29191", "name": "hydroxyl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9707647", "map_id": "CHEBI:16234", "name": "hydroxide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10092212", "map_id": "none", "name": "COHb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10081561", "map_id": "none", "name": "TP53 forms homotetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066422", "map_id": "P67939", "name": "TP53", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10091685", "map_id": "none", "name": "Histone H3.3 deposition at telomere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091677", "map_id": "none", "name": "Telomere:Shelterin:Nucleosome:ATRX:DAXX", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MGU0", "map_id": "F1MGU0", "name": "DAXX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036227", "map_id": "ENSBTAT00000036227", "name": "DAXX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCT3", "map_id": "Q0VCT3", "name": "TERF2IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020830", "map_id": "ENSBTAT00000020830", "name": "TERF2IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MMS4", "map_id": "F1MMS4", "name": "TERF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010016", "map_id": "ENSBTAT00000010016", "name": "TERF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A3KN17", "map_id": "A3KN17", "name": "TINF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003522", "map_id": "ENSBTAT00000003522", "name": "TINF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGK3", "map_id": "E1BGK3", "name": "POT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017541", "map_id": "ENSBTAT00000017541", "name": "POT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGN3", "map_id": "E1BGN3", "name": "HIST2H3D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033058", "map_id": "ENSBTAT00000033058", "name": "HIST2H3D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035227", "map_id": "Q5E9F8", "name": "H3-3B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10091683", "map_id": "none", "name": "Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10040161", "map_id": "E1BGN3", "name": "HIST2H3D", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10038540", "map_id": "none", "name": "Alignment Of The RNA Template On The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10038538", "map_id": "none", "name": "Telomerase RNP:G-strand telomeric chromosome end", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:15986", "map_id": "CHEBI:15986", "name": "CHEBI:15986", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N079", "map_id": "F1N079", "name": "RTEL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028108", "map_id": "ENSBTAT00000028108", "name": "RTEL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBF2", "map_id": "Q3ZBF2", "name": "NOP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036177", "map_id": "ENSBTAT00000036177", "name": "NOP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWH5", "map_id": "A7YWH5", "name": "DKC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017339", "map_id": "ENSBTAT00000017339", "name": "DKC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1J8", "map_id": "A0A3Q1M1J8", "name": "GAR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066873", "map_id": "ENSBTAT00000066873", "name": "GAR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LGY5", "map_id": "A0A3Q1LGY5", "name": "WRAP53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071579", "map_id": "ENSBTAT00000071579", "name": "WRAP53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5E950", "map_id": "Q5E950", "name": "NHP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008363", "map_id": "ENSBTAT00000008363", "name": "NHP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038529", "map_id": "none", "name": "Telomerase RNP Bound and base-paired to the Telomeric Chromosome End", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10038947", "map_id": "none", "name": "Elongation of Extended Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_30187", "map_id": "CHEBI:18077", "name": "dTTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10038531", "map_id": "none", "name": "Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30185", "map_id": "CHEBI:16311", "name": "dCTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29892", "map_id": "CHEBI:16497", "name": "dGTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29604", "map_id": "CHEBI:16284", "name": "dATP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10038542", "map_id": "none", "name": "Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10038949", "map_id": "none", "name": "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10038534", "map_id": "none", "name": "Elongation Of The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10087577", "map_id": "none", "name": "Association of procollagen type XXVII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062035", "map_id": "A0A3Q1M646", "name": "COL27A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000081723", "map_id": "ENSBTAT00000081723", "name": "COL27A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062840", "map_id": "none", "name": "C-linked procollagen type XXVII trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A3Q1M646", "map_id": "A0A3Q1M646", "name": "COL27A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087579", "map_id": "none", "name": "Association of procollagen type XXI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062810", "map_id": "none", "name": "Alpha-1(XXI) chains", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A3Q1MQC5", "map_id": "A0A3Q1MQC5", "name": "3x4Hyp-GlcGalHyl-COL21A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074238", "map_id": "ENSBTAT00000074238", "name": "3x4Hyp-GlcGalHyl-COL21A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062812", "map_id": "none", "name": "C-linked procollagen type XXI trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087581", "map_id": "none", "name": "Association of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060135", "map_id": "F1MKG2", "name": "COL6A2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060159", "map_id": "E1BB91", "name": "COL6A3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060111", "map_id": "E1BI98", "name": "COL6A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060183", "map_id": "none", "name": "Collagen type VI", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087583", "map_id": "none", "name": "Association of procollagen type XXV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062400", "map_id": "E1BKJ9", "name": "COL26A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000044319", "map_id": "ENSBTAT00000044319", "name": "COL26A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062823", "map_id": "none", "name": "C-linked procollagen type XXV trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "E1BKJ9", "map_id": "E1BKJ9", "name": "COL26A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087569", "map_id": "none", "name": "Association of procollagen type XVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062025", "map_id": "G3MXK9", "name": "COL16A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000065364", "map_id": "ENSBTAT00000065364", "name": "COL16A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062790", "map_id": "none", "name": "C-linked procollagen type XVI trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "G3MXK9", "map_id": "G3MXK9", "name": "COL16A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087571", "map_id": "none", "name": "Association of procollagen type XXIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062031", "map_id": "F1MSJ7", "name": "COL23A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000017548", "map_id": "ENSBTAT00000017548", "name": "COL23A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062821", "map_id": "none", "name": "C-linked procollagen type XXIII trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1MSJ7", "map_id": "F1MSJ7", "name": "COL23A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087573", "map_id": "none", "name": "Association of procollagen type V", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062017", "map_id": "G3MZI7", "name": "COL5A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062045", "map_id": "F1MJQ6", "name": "COL5A3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062041", "map_id": "A0A3Q1MDT9", "name": "COL5A2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062749", "map_id": "none", "name": "C-linked procollagen type V trimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10062071", "map_id": "none", "name": "Association of procollagen type XVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062037", "map_id": "A0A3Q1LYA4", "name": "COL28A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000067622", "map_id": "ENSBTAT00000067622", "name": "COL28A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062069", "map_id": "none", "name": "C-linked procollagen type XXVIII trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "A0A3Q1LYA4", "map_id": "A0A3Q1LYA4", "name": "COL28A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087563", "map_id": "none", "name": "Association of procollagen type XX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062027", "map_id": "G3N021", "name": "COL20A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000063888", "map_id": "ENSBTAT00000063888", "name": "COL20A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10062801", "map_id": "none", "name": "C-linked procollagen type XX trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "G3N021", "map_id": "G3N021", "name": "COL20A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087565", "map_id": "none", "name": "Association of procollagen type XV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062023", "map_id": "A0A3Q1M0N0", "name": "COL15A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062781", "map_id": "none", "name": "C-linked procollagen type XV trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087567", "map_id": "none", "name": "Association of procollagen type VIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062019", "map_id": "A7E303", "name": "COL8A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062043", "map_id": "F1MJR6", "name": "COL8A2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062763", "map_id": "none", "name": "C-linked procollagen type VIII trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087585", "map_id": "none", "name": "Association of procollagen type XXVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062033", "map_id": "E1BKJ9", "name": "COL26A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062832", "map_id": "none", "name": "C-linked procollagen type XXVI trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087587", "map_id": "none", "name": "Association of procollagen type XIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062021", "map_id": "F6RND5", "name": "COL13A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062772", "map_id": "none", "name": "C-linked procollagen type XIII trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087589", "map_id": "none", "name": "Association of procollagen type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062015", "map_id": "P02459", "name": "COL2A1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062709", "map_id": "none", "name": "C-linked procollagen type II trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10044446", "map_id": "none", "name": "Formation of CSL-NICD coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044438", "map_id": "F1MD32", "name": "CREBBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044434", "map_id": "none", "name": "PCAF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10044410", "map_id": "Q3SZ41", "name": "RBPJ", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044424", "map_id": "none", "name": "MAML", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10044444", "map_id": "none", "name": "CSL NICD coactivator complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044726", "map_id": "none", "name": "Formation of CSL NCOR corepressor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044722", "map_id": "none", "name": "HDAC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MXW3", "map_id": "A0A3Q1MXW3", "name": "HDAC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084577", "map_id": "ENSBTAT00000084577", "name": "HDAC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044704", "map_id": "none", "name": "TBL1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10044724", "map_id": "none", "name": "RBPJ:NCOR corepressor complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092287", "map_id": "none", "name": "FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10092281", "map_id": "none", "name": "BACH1:FBXL17:SCF (SKP2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LUD8", "map_id": "A0A3Q1LUD8", "name": "FBXL17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069043", "map_id": "ENSBTAT00000069043", "name": "FBXL17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10092277", "map_id": "A0A3Q1LUD8", "name": "FBXL17", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10092284", "map_id": "E1BJL3", "name": "BACH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10092273", "map_id": "none", "name": "BACH1 translocates from the nucleoplasm to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10092261", "map_id": "E1BJL3", "name": "BACH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3785707", "map_id": "CHEBI:26523", "name": "ROS", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10092289", "map_id": "none", "name": "BACH1:FBXL17 binds SCF(SKP2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10092279", "map_id": "none", "name": "BACH1:FBXL17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092293", "map_id": "none", "name": "FBXL17 binds BACH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10057639", "map_id": "none", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057636", "map_id": "none", "name": "TWIK channels", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B9M4", "map_id": "E1B9M4", "name": "KCNK7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014309", "map_id": "ENSBTAT00000014309", "name": "KCNK7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065673", "map_id": "none", "name": "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065666", "map_id": "none", "name": "RLBP1:11cRPALM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16254", "map_id": "CHEBI:16254", "name": "CHEBI:16254", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065670", "map_id": "A0A3Q1LSC4", "name": "AWAT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000074877", "map_id": "ENSBTAT00000074877", "name": "AWAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091560", "map_id": "none", "name": "OPN1MW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048186", "map_id": "Q9BGI7", "name": "OPN1LW", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10065649", "map_id": "Q9BGI7", "name": "OPN1LW", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10065675", "map_id": "none", "name": "OPN1LW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10065677", "map_id": "none", "name": "11cROL translocates from Muller cells to cone photoreceptor cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2473606", "map_id": "CHEBI:16302", "name": "11cROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065679", "map_id": "none", "name": "RBP3 regulates atROL taken up by Muller cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2473607", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2473617", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065664", "map_id": "none", "name": "Photons induce isomerisation of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74000", "compartment_display": "photoreceptor outer segment membrane" }, { "id": "species_10065654", "map_id": "none", "name": "11c-retinyl-cone opsins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "species_10065662", "map_id": "none", "name": "at-retinyl-cone opsins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "reaction_10065683", "map_id": "none", "name": "RLBP1 binds atROL to form RLBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065681", "map_id": "none", "name": "RLBP1:atROL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065687", "map_id": "none", "name": "at-retinyl is hydrolysed from R* to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065685", "map_id": "none", "name": "Cone apo-opsins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "reaction_10091558", "map_id": "none", "name": "OPN1SW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048190", "map_id": "P51490", "name": "OPN1SW", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10065652", "map_id": "P51490", "name": "OPN1SW", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10068899", "map_id": "none", "name": "CEBPB homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068891", "map_id": "A0A3Q1NLC4", "name": "phospho-CEBPB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000086463", "map_id": "ENSBTAT00000086463", "name": "phospho-CEBPB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10068893", "map_id": "none", "name": "p-T235,S321-CEBPB homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1NLC4", "map_id": "A0A3Q1NLC4", "name": "phospho-CEBPB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040355", "map_id": "none", "name": "Association of INK4 family proteins with CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040351", "map_id": "none", "name": "CDK4,CDK6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BC36", "map_id": "E1BC36", "name": "CDK6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068675", "map_id": "ENSBTAT00000068675", "name": "CDK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040345", "map_id": "none", "name": "INK4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LYR9", "map_id": "A0A3Q1LYR9", "name": "CDKN2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083400", "map_id": "ENSBTAT00000083400", "name": "CDKN2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBB9", "map_id": "A7MBB9", "name": "CDKN2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014685", "map_id": "ENSBTAT00000014685", "name": "CDKN2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040353", "map_id": "none", "name": "CDK4,CDK6:INK4", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10088026", "map_id": "none", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_2173763", "map_id": "CHEBI:60479", "name": "lysoPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8954142", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8952253", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10088023", "map_id": "Q8WMP9", "name": "PLA2G15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000009888", "map_id": "ENSBTAT00000009888", "name": "PLA2G15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058910", "map_id": "none", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524028", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498750", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10058868", "map_id": "none", "name": "PLA2(8)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10058871", "map_id": "none", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_975614", "map_id": "CHEBI:16728", "name": "2-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10057007", "map_id": "none", "name": "AQP1 tetramer transports CO2 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237009", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049238", "map_id": "none", "name": "AQP1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P47865", "map_id": "P47865", "name": "AQP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000993", "map_id": "ENSBTAT00000000993", "name": "AQP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081968", "map_id": "none", "name": "CYB5Rs reduce MetHb to HbA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081949", "map_id": "none", "name": "MetHb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081955", "map_id": "none", "name": "HbA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10081965", "map_id": "none", "name": "CYB5Rs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LIS5", "map_id": "A0A3Q1LIS5", "name": "CYB5RL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068812", "map_id": "ENSBTAT00000068812", "name": "CYB5RL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MXD6", "map_id": "A0A3Q1MXD6", "name": "CYB5R2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072609", "map_id": "ENSBTAT00000072609", "name": "CYB5R2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058790", "map_id": "none", "name": "CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058787", "map_id": "none", "name": "CA1:Zn2+,CA2:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1LZA1", "map_id": "Q1LZA1", "name": "CA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045723", "map_id": "ENSBTAT00000045723", "name": "CA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0H3", "map_id": "F1N0H3", "name": "CA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023581", "map_id": "ENSBTAT00000023581", "name": "CA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057062", "map_id": "none", "name": "Hemoglobin A is protonated and carbamated causing release of oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057046", "map_id": "none", "name": "OxyHbA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10057060", "map_id": "none", "name": "Protonated Carbamino DeoxyHbA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10037739", "map_id": "none", "name": "Translocation of PMAIP1 (NOXA) to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037735", "map_id": "A0A3Q1NFP6", "name": "PMAIP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000071269", "map_id": "ENSBTAT00000071269", "name": "PMAIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037737", "map_id": "A0A3Q1NFP6", "name": "PMAIP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10058985", "map_id": "none", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524083", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1498773", "map_id": "CHEBI:60430", "name": "MLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524089", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10058952", "map_id": "A0A3Q1MVZ7", "name": "TAZ", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000079163", "map_id": "ENSBTAT00000079163", "name": "TAZ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058955", "map_id": "none", "name": "MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524075", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524079", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10058993", "map_id": "none", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524069", "map_id": "CHEBI:60430", "name": "MLCL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524081", "map_id": "CHEBI:28494", "name": "CL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10035773", "map_id": "A0A3Q1LJ33", "name": "LCLAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058998", "map_id": "none", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524080", "map_id": "CHEBI:60431", "name": "DLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10045466", "map_id": "none", "name": "Connexin 36 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10045463", "map_id": "none", "name": "Connexin 36 Gap Junction Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q866T7", "map_id": "Q866T7", "name": "GJD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028966", "map_id": "ENSBTAT00000028966", "name": "GJD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045455", "map_id": "none", "name": "Connexin 62 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045452", "map_id": "none", "name": "Connexin 62 Gap Junction Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BLU3", "map_id": "E1BLU3", "name": "GJA10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015039", "map_id": "ENSBTAT00000015039", "name": "GJA10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045444", "map_id": "none", "name": "Pannexin 1/Pannexin2 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045441", "map_id": "none", "name": "Pannexin 1/Pannexin 2 Gap Junction Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "D7R519", "map_id": "D7R519", "name": "PANX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015932", "map_id": "ENSBTAT00000015932", "name": "PANX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5X7", "map_id": "G5E5X7", "name": "PANX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037612", "map_id": "ENSBTAT00000037612", "name": "PANX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084238", "map_id": "none", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane" }, { "id": "species_10084224", "map_id": "F1MB46", "name": "TBC1D10A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_19363", "compartment_display": "microvillus", "complex": "false" }, { "id": "ENSBTAT00000055485", "map_id": "ENSBTAT00000055485", "name": "TBC1D10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084234", "map_id": "none", "name": "ARF6:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "G3N3N1", "map_id": "G3N3N1", "name": "ARF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063023", "map_id": "ENSBTAT00000063023", "name": "ARF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084236", "map_id": "none", "name": "TBC1D10A:ARF6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "F1MB46", "map_id": "F1MB46", "name": "TBC1D10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084291", "map_id": "none", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10084286", "map_id": "none", "name": "RAB33:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BJA0", "map_id": "E1BJA0", "name": "RAB33A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083670", "map_id": "ENSBTAT00000083670", "name": "RAB33A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084288", "map_id": "none", "name": "RAB33:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10084272", "map_id": "E1BHZ5", "name": "TBC1D25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5683636", "compartment_display": "autophagosome", "complex": "false" }, { "id": "ENSBTAT00000012236", "map_id": "ENSBTAT00000012236", "name": "TBC1D25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084261", "map_id": "none", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10084252", "map_id": "none", "name": "RAB7:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "Q08DE8", "map_id": "Q08DE8", "name": "RAB7B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016976", "map_id": "ENSBTAT00000016976", "name": "RAB7B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084254", "map_id": "none", "name": "RAB7:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10084259", "map_id": "A0A3Q1MTW0", "name": "TBC1D15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000082752", "map_id": "ENSBTAT00000082752", "name": "TBC1D15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084228", "map_id": "none", "name": "TBC1D10A binds JFC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_19363", "compartment_display": "microvillus" }, { "id": "species_10084220", "map_id": "A0A3Q1M443", "name": "SYTL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_172780", "compartment_display": "microvillus membrane", "complex": "false" }, { "id": "ENSBTAT00000077895", "map_id": "ENSBTAT00000077895", "name": "SYTL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084226", "map_id": "none", "name": "TBC1D10A:JFC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_172780", "compartment_display": "microvillus membrane", "complex": "true" }, { "id": "A0A3Q1M443", "map_id": "A0A3Q1M443", "name": "SYTL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084276", "map_id": "none", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10084268", "map_id": "none", "name": "ATG8 homologues", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "species_10084274", "map_id": "none", "name": "TBC1D25:ATG8 homoogues", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "E1BHZ5", "map_id": "E1BHZ5", "name": "TBC1D25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084246", "map_id": "none", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10084242", "map_id": "F1N746", "name": "RABGAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000061025", "map_id": "ENSBTAT00000061025", "name": "RABGAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083720", "map_id": "none", "name": "RAB6:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10084244", "map_id": "none", "name": "RABGAP1:RAB6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1N746", "map_id": "F1N746", "name": "RABGAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044801", "map_id": "none", "name": "Agmatine + H2O <=> putrescine + urea", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_351164", "map_id": "CHEBI:17431", "name": "AGM", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29610", "map_id": "CHEBI:17148", "name": "Putrescine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044798", "map_id": "A0A3Q1N858", "name": "AGMAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5462", "compartment_display": "mitochondrion", "complex": "false" }, { "id": "ENSBTAT00000085149", "map_id": "ENSBTAT00000085149", "name": "AGMAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041177", "map_id": "none", "name": "CYP7A1 7-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192114", "map_id": "CHEBI:17500", "name": "7 alpha-hydroxycholesterol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041174", "map_id": "none", "name": "Cytochrome P450 (CYP7A1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "E1BM29", "map_id": "E1BM29", "name": "CYP7A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006957", "map_id": "ENSBTAT00000006957", "name": "CYP7A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041500", "map_id": "none", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194634", "map_id": "CHEBI:16521", "name": "LNSOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194644", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041497", "map_id": "Q4PJW3", "name": "CYP51A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000002582", "map_id": "ENSBTAT00000002582", "name": "CYP51A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041206", "map_id": "none", "name": "CYP27A1 27-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193846", "map_id": "CHEBI:17703", "name": "27OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10044232", "map_id": "none", "name": "CYP1B1 4-hydroxylates EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_211973", "map_id": "CHEBI:62845", "name": "4OH-EST17b", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044229", "map_id": "F1MNG1", "name": "CYP1B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10035975", "map_id": "none", "name": "AHR:TCDD:ARNT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1ML85", "map_id": "F1ML85", "name": "AHR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010187", "map_id": "ENSBTAT00000010187", "name": "AHR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28119", "map_id": "CHEBI:28119", "name": "CHEBI:28119", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYL2", "map_id": "F1MYL2", "name": "ARNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016391", "map_id": "ENSBTAT00000016391", "name": "ARNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041195", "map_id": "none", "name": "CYP7B1 7-hydroxylates 25OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192148", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10041094", "map_id": "none", "name": "Cytochrome P450 (CYP7B1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1NAD5", "map_id": "A0A3Q1NAD5", "name": "CYP7B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070426", "map_id": "ENSBTAT00000070426", "name": "CYP7B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043964", "map_id": "none", "name": "CYP2R1 25-hydroxylates VD3 to 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8963870", "map_id": "CHEBI:28940", "name": "VD3", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_8963879", "map_id": "CHEBI:17933", "name": "25(OH)D", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10043961", "map_id": "A0A3Q1MPH7", "name": "CYP2R1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000084891", "map_id": "ENSBTAT00000084891", "name": "CYP2R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044225", "map_id": "none", "name": "CYP24A1 24-hydroxylates CTL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_215607", "map_id": "CHEBI:17823", "name": "CTL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_215622", "map_id": "CHEBI:63911", "name": "CTLA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10043907", "map_id": "E1BKM8", "name": "CYP24A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000003588", "map_id": "ENSBTAT00000003588", "name": "CYP24A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043971", "map_id": "none", "name": "CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209804", "map_id": "CHEBI:17933", "name": "25(OH)D", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_209800", "map_id": "CHEBI:17823", "name": "1,25(OH)2D", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043968", "map_id": "E1BN35", "name": "CYP27B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000022485", "map_id": "ENSBTAT00000022485", "name": "CYP27B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044293", "map_id": "none", "name": "CYP26A1,B1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10044280", "map_id": "none", "name": "CYP2F1 dehydrogenates 3-methylindole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_213162", "map_id": "CHEBI:9171", "name": "MIND", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_213163", "map_id": "CHEBI:63905", "name": "3MEIN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044277", "map_id": "none", "name": "Cytochrome P450 (CYP2F1 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G3MYW0", "map_id": "G3MYW0", "name": "CYP2F1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063781", "map_id": "ENSBTAT00000063781", "name": "CYP2F1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044218", "map_id": "none", "name": "CYP2C19 5-hydroxylates omeprazole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211892", "map_id": "CHEBI:7772", "name": "Losec", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211944", "map_id": "CHEBI:63840", "name": "HOMZ", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044201", "map_id": "none", "name": "Cytochrome P450 (CYP2C8 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10044250", "map_id": "none", "name": "CYP2D6 4-hydroxylates debrisoquine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211993", "map_id": "CHEBI:34665", "name": "DSQ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211952", "map_id": "CHEBI:63800", "name": "HDBQ", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10035908", "map_id": "none", "name": "Cytochrome P450 (CYP2D6 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2KJJ2", "map_id": "Q2KJJ2", "name": "MGC127055", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000869", "map_id": "ENSBTAT00000000869", "name": "MGC127055", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044477", "map_id": "none", "name": "CYP3A4,5 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_156522", "map_id": "CHEBI:2504", "name": "AFB1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_156523", "map_id": "CHEBI:30725", "name": "AFXBO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044474", "map_id": "none", "name": "Cytochrome P450 (CYP3A5 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10044223", "map_id": "none", "name": "CYP3A4 can N-demethylate loperamide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_213155", "map_id": "CHEBI:6532", "name": "LPAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_213151", "map_id": "CHEBI:64043", "name": "N-demethylated loperamide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044220", "map_id": "none", "name": "Cytochrome P450 (CYPIIIA4 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10035865", "map_id": "none", "name": "N-atom dealkylation of caffeine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_143501", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_76424", "map_id": "CHEBI:25858", "name": "Paraxanthine", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10035858", "map_id": "F1MHN9", "name": "CYP1A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10035861", "map_id": "none", "name": "N-hydroxylation of 4-aminobiphenyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_47687", "map_id": "CHEBI:1784", "name": "ABPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_34889", "map_id": "CHEBI:16580", "name": "NHABP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10044275", "map_id": "none", "name": "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211939", "map_id": "CHEBI:8107", "name": "Phenytoin", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211927", "map_id": "CHEBI:63804", "name": "HPHT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044272", "map_id": "none", "name": "Cytochrome P450 (CYP2C18 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MRH2", "map_id": "F1MRH2", "name": "CYP2C18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040300", "map_id": "ENSBTAT00000040300", "name": "CYP2C18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044182", "map_id": "none", "name": "CYP3A7 can 6beta-hydroxylate testosterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10044179", "map_id": "none", "name": "Cytochrome P450 (CYP3A7 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10035977", "map_id": "none", "name": "Ethylene is oxidized to Ethylene oxide by CYP1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_38985", "map_id": "CHEBI:18153", "name": "C2H4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_38987", "map_id": "CHEBI:27561", "name": "EtO", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10035962", "map_id": "F1MM10", "name": "CYP1A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10044265", "map_id": "none", "name": "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211855", "map_id": "CHEBI:27999", "name": "TBM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211937", "map_id": "CHEBI:63799", "name": "HTOLB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044262", "map_id": "none", "name": "Cytochrome P450 (CYP2C9 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10044204", "map_id": "none", "name": "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211906", "map_id": "CHEBI:45863", "name": "PTXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211894", "map_id": "CHEBI:63859", "name": "HPTXL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10044270", "map_id": "none", "name": "Cyclophosphamide is 4-hydroxylated by CYP2B6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_211977", "map_id": "CHEBI:4026", "name": "CPM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_211967", "map_id": "CHEBI:1864", "name": "HCPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044267", "map_id": "none", "name": "Cytochrome P450 (CYP2B6 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MU42", "map_id": "A0A3Q1MU42", "name": "CYP2B6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079854", "map_id": "ENSBTAT00000079854", "name": "CYP2B6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044167", "map_id": "none", "name": "Coumarin is 7-hydroxylated by CYP2A13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_76452", "map_id": "CHEBI:27510", "name": "HCOU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044164", "map_id": "none", "name": "Cytochrome P450 (CYP2A13 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G3MYH2", "map_id": "G3MYH2", "name": "LOC540707", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065779", "map_id": "ENSBTAT00000065779", "name": "LOC540707", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035911", "map_id": "none", "name": "O-atom dealkylation of dextromethorphan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_39703", "map_id": "none", "name": "DEXM", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_76455", "map_id": "none", "name": "DEXT", "type": "product", "sub_type": "other", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10035878", "map_id": "none", "name": "Coumarin is 7-hydroxylated by CYP2A6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10035875", "map_id": "none", "name": "Cytochrome P450 (CYP2A3 based)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10059035", "map_id": "none", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500603", "map_id": "CHEBI:16732", "name": "CDP-ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10059032", "map_id": "none", "name": "EPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q17QM4", "map_id": "Q17QM4", "name": "SELENOI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010310", "map_id": "ENSBTAT00000010310", "name": "SELENOI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059082", "map_id": "none", "name": "PETA is dephosphorylated to ETA by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10059130", "map_id": "none", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059127", "map_id": "none", "name": "PCYT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MLB5", "map_id": "A0A3Q1MLB5", "name": "PCYT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070509", "map_id": "ENSBTAT00000070509", "name": "PCYT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059150", "map_id": "none", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10059147", "map_id": "none", "name": "CHK/ETNK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MRD9", "map_id": "F1MRD9", "name": "ETNK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024637", "map_id": "ENSBTAT00000024637", "name": "ETNK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076994", "map_id": "none", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696414", "map_id": "CHEBI:17553", "name": "PETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113532", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076991", "map_id": "none", "name": "PXLP-K278-ETNPPL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q5E9S4", "map_id": "Q5E9S4", "name": "ETNPPL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013587", "map_id": "ENSBTAT00000013587", "name": "ETNPPL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077004", "map_id": "none", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5696449", "map_id": "CHEBI:17408", "name": "MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6782195", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058892", "map_id": "none", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498728", "map_id": "CHEBI:17389", "name": "2-MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500594", "map_id": "CHEBI:17855", "name": "TAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10058889", "map_id": "G5E554", "name": "PNPLA3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000004368", "map_id": "ENSBTAT00000004368", "name": "PNPLA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059006", "map_id": "none", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058894", "map_id": "none", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058961", "map_id": "none", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058819", "map_id": "none", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500593", "map_id": "CHEBI:35366", "name": "fatty acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10058816", "map_id": "none", "name": "MGLL dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LUK0", "map_id": "A0A3Q1LUK0", "name": "MGLL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058948", "map_id": "none", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10083572", "map_id": "none", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10083569", "map_id": "A0A452DI75", "name": "DGAT2L6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000010259", "map_id": "ENSBTAT00000010259", "name": "DGAT2L6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038938", "map_id": "none", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10038932", "map_id": "none", "name": "AMPK heterotrimer (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10038936", "map_id": "none", "name": "AMPK heterotrimer:AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10083614", "map_id": "none", "name": "ADIPOQ trimer binds ADIPOR dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10083610", "map_id": "none", "name": "ADIPOR dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3T0U4", "map_id": "Q3T0U4", "name": "ADIPOR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040283", "map_id": "ENSBTAT00000040283", "name": "ADIPOR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32KM7", "map_id": "Q32KM7", "name": "ADIPOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011923", "map_id": "ENSBTAT00000011923", "name": "ADIPOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083594", "map_id": "none", "name": "ADIPOQ trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M564", "map_id": "A0A3Q1M564", "name": "ADIPOQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077795", "map_id": "ENSBTAT00000077795", "name": "ADIPOQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083612", "map_id": "none", "name": "ADIPOQ trimer:ADIPOR dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10060553", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806289", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806212", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_10060465", "map_id": "A0A3Q1LHW5", "name": "MTMR4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000078957", "map_id": "ENSBTAT00000078957", "name": "MTMR4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060537", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806195", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806198", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_10060489", "map_id": "none", "name": "PIK3C2A:Ca2+/Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BE68", "map_id": "E1BE68", "name": "PIK3C2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046627", "map_id": "ENSBTAT00000046627", "name": "PIK3C2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060468", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "reaction_10088526", "map_id": "none", "name": "ADPRHL2 hydrolyses poly(ADP-ribose)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8952909", "map_id": "none", "name": "poly(ADP-ribose)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_8952905", "map_id": "CHEBI:57967", "name": "ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10088523", "map_id": "F1MWJ3", "name": "ADPRS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000028950", "map_id": "ENSBTAT00000028950", "name": "ADPRS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037674", "map_id": "none", "name": "Sequestration of BAD protein by 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037670", "map_id": "none", "name": "14-3-3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M2Q2", "map_id": "A0A3Q1M2Q2", "name": "YWHAQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAP00000064310", "map_id": "ENSBTAP00000064310", "name": "YWHAQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037644", "map_id": "F1MUT9", "name": "phospho-BAD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037672", "map_id": "none", "name": "14-3-3 proteins:p-S99-BAD complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MUT9", "map_id": "F1MUT9", "name": "phospho-BAD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037678", "map_id": "none", "name": "Translocation of activated BAD protein to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037626", "map_id": "F1MUT9", "name": "BAD", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10037630", "map_id": "none", "name": "BAD displaces tBID from BCL-2 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10037275", "map_id": "none", "name": "tBID:BCL-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "F6R2C4", "map_id": "F6R2C4", "name": "BCL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025701", "map_id": "ENSBTAT00000025701", "name": "BCL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037628", "map_id": "none", "name": "BAD:BCL-2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10047900", "map_id": "none", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_114521", "compartment_display": "platelet dense tubular network membrane" }, { "id": "species_427899", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114580", "compartment_display": "platelet dense tubular network lumen", "complex": "false" }, { "id": "species_139827", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114580", "compartment_display": "platelet dense tubular network lumen", "complex": "false" }, { "id": "species_10047897", "map_id": "A0A3Q1M9U0", "name": "ATP2A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_114521", "compartment_display": "platelet dense tubular network membrane", "complex": "false" }, { "id": "reaction_10076824", "map_id": "none", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_5696066", "map_id": "none", "name": "MAG,DAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_6814795", "map_id": "CHEBI:17408", "name": "MAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5696069", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696026", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696037", "map_id": "none", "name": "LPA,PA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_10076821", "map_id": "none", "name": "AGK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "A0A3Q1MFM9", "map_id": "A0A3Q1MFM9", "name": "AGK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074114", "map_id": "ENSBTAT00000074114", "name": "AGK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085340", "map_id": "none", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085337", "map_id": "none", "name": "PITPNM1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1B9I9", "map_id": "E1B9I9", "name": "PITPNM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013851", "map_id": "ENSBTAT00000013851", "name": "PITPNM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUM3", "map_id": "A0A3Q1MUM3", "name": "PITPNM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079883", "map_id": "ENSBTAT00000079883", "name": "PITPNM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N293", "map_id": "A0A3Q1N293", "name": "PITPNM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069345", "map_id": "ENSBTAT00000069345", "name": "PITPNM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059091", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426955", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10059088", "map_id": "none", "name": "CDS1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G3MZU2", "map_id": "G3MZU2", "name": "CDS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065725", "map_id": "ENSBTAT00000065725", "name": "CDS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059044", "map_id": "none", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426910", "map_id": "CHEBI:17268", "name": "Ins", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10059041", "map_id": "none", "name": "CDIPT:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q3T103", "map_id": "Q3T103", "name": "CDIPT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010454", "map_id": "ENSBTAT00000010454", "name": "CDIPT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071344", "map_id": "none", "name": "CPNEs bind PL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10071340", "map_id": "none", "name": "CPNEs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q2KHY1", "map_id": "Q2KHY1", "name": "CPNE6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002436", "map_id": "ENSBTAT00000002436", "name": "CPNE6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_171142", "map_id": "CHEBI:16247", "name": "PL", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10071342", "map_id": "none", "name": "CPNEs:PL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10059849", "map_id": "none", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_33625", "map_id": "CHEBI:18303", "name": "PS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602419", "map_id": "CHEBI:52603", "name": "1-acyl LPS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10058943", "map_id": "none", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498724", "map_id": "CHEBI:52603", "name": "1-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10085310", "map_id": "none", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1806234", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10085307", "map_id": "none", "name": "OSBPL5,8,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MI45", "map_id": "A0A3Q1MI45", "name": "OSBPL8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070851", "map_id": "ENSBTAT00000070851", "name": "OSBPL8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFD9", "map_id": "F1MFD9", "name": "OSBPL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012114", "map_id": "ENSBTAT00000012114", "name": "OSBPL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWY5", "map_id": "A0A3Q1LWY5", "name": "OSBPL5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073265", "map_id": "ENSBTAT00000073265", "name": "OSBPL5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058945", "map_id": "none", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058880", "map_id": "none", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058800", "map_id": "G8JL05", "name": "LPCAT3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058916", "map_id": "none", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498722", "map_id": "CHEBI:37646", "name": "2-acyl LPS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10059014", "map_id": "none", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059011", "map_id": "none", "name": "PLA2(10)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10059016", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1483256", "map_id": "CHEBI:17517", "name": "PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498740", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10059018", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058826", "map_id": "none", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524047", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524038", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10059021", "map_id": "none", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498730", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10058877", "map_id": "none", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058812", "map_id": "none", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058913", "map_id": "none", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524027", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10058983", "map_id": "none", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524085", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10058931", "map_id": "none", "name": "PLA2G", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10059847", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_1602415", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10058934", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "reaction_10058809", "map_id": "none", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058806", "map_id": "none", "name": "LPCAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1MPE0", "map_id": "A0A3Q1MPE0", "name": "LPCAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079571", "map_id": "ENSBTAT00000079571", "name": "LPCAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058970", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058829", "map_id": "none", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10058990", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10058987", "map_id": "none", "name": "PLA2(5)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10059856", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_1602390", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10059858", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10085826", "map_id": "none", "name": "THEM86B hydrolyses PMCHO, PMETAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8874447", "map_id": "none", "name": "PMCHO, PMETAM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "CHEBI:17810", "map_id": "CHEBI:17810", "name": "CHEBI:17810", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17476", "map_id": "CHEBI:17476", "name": "CHEBI:17476", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8874450", "map_id": "none", "name": "GPCHO, GPETAM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "CHEBI:36313", "map_id": "CHEBI:36313", "name": "CHEBI:36313", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36314", "map_id": "CHEBI:36314", "name": "CHEBI:36314", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085823", "map_id": "Q3T0W0", "name": "TMEM86B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000076823", "map_id": "ENSBTAT00000076823", "name": "TMEM86B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058996", "map_id": "none", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10059121", "map_id": "none", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059118", "map_id": "Q2KHY9", "name": "PTDSS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000018461", "map_id": "ENSBTAT00000018461", "name": "PTDSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059073", "map_id": "none", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10059070", "map_id": "A0A3Q1MFE2", "name": "PTDSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000077015", "map_id": "ENSBTAT00000077015", "name": "PTDSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10059101", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_110577", "map_id": "CHEBI:17677", "name": "CTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10059098", "map_id": "A0JNC1", "name": "CDS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000007970", "map_id": "ENSBTAT00000007970", "name": "CDS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057390", "map_id": "none", "name": "Activation of HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057387", "map_id": "none", "name": "HCN channel bound to cAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BM97", "map_id": "E1BM97", "name": "HCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061021", "map_id": "ENSBTAT00000061021", "name": "HCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BL87", "map_id": "E1BL87", "name": "HCN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022679", "map_id": "ENSBTAT00000022679", "name": "HCN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIS4", "map_id": "E1BIS4", "name": "HCN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023219", "map_id": "ENSBTAT00000023219", "name": "HCN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057607", "map_id": "none", "name": "Binding of cAMP to HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057385", "map_id": "none", "name": "HCN channels", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049326", "map_id": "none", "name": "NACT co-transports trivalent citrate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_433138", "map_id": "CHEBI:30769", "name": "CIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049323", "map_id": "E1B8V0", "name": "SLC13A5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000006144", "map_id": "ENSBTAT00000006144", "name": "SLC13A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049333", "map_id": "none", "name": "NaS1 co-transports sulphate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049330", "map_id": "A0A3Q1LUW1", "name": "SLC13A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000078998", "map_id": "ENSBTAT00000078998", "name": "SLC13A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051305", "map_id": "none", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_561049", "map_id": "none", "name": "OAT1-3 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:104011", "map_id": "CHEBI:104011", "name": "CHEBI:104011", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_561052", "map_id": "CHEBI:2453", "name": "ACV", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_561078", "map_id": "none", "name": "OAT1-3 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051302", "map_id": "none", "name": "OAT1-3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MIJ1", "map_id": "F1MIJ1", "name": "SLC22A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018132", "map_id": "ENSBTAT00000018132", "name": "SLC22A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N1R8", "map_id": "G3N1R8", "name": "LOC519202", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064695", "map_id": "ENSBTAT00000064695", "name": "LOC519202", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MII8", "map_id": "F1MII8", "name": "SLC22A8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018139", "map_id": "ENSBTAT00000018139", "name": "SLC22A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051314", "map_id": "none", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429056", "map_id": "CHEBI:17775", "name": "urate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_30034", "map_id": "CHEBI:17775", "name": "urate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051311", "map_id": "A0A3Q1MUJ2", "name": "SLC22A12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068956", "map_id": "ENSBTAT00000068956", "name": "SLC22A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051307", "map_id": "none", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549266", "map_id": "none", "name": "OCT2 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:46020", "map_id": "CHEBI:46020", "name": "CHEBI:46020", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:6801", "map_id": "CHEBI:6801", "name": "CHEBI:6801", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16737", "map_id": "CHEBI:16737", "name": "CHEBI:16737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:65133", "map_id": "CHEBI:65133", "name": "CHEBI:65133", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:641", "map_id": "CHEBI:641", "name": "CHEBI:641", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:31941", "map_id": "CHEBI:31941", "name": "CHEBI:31941", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_549237", "map_id": "none", "name": "OCT2 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10051281", "map_id": "G3MYQ6", "name": "LOC515551", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000055483", "map_id": "ENSBTAT00000055483", "name": "LOC515551", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051325", "map_id": "none", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_597604", "map_id": "none", "name": "SLC22A18 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_597623", "map_id": "none", "name": "SLC22A18 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051322", "map_id": "F1MWZ2", "name": "SLC22A18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000016935", "map_id": "ENSBTAT00000016935", "name": "SLC22A18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051276", "map_id": "none", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549261", "map_id": "CHEBI:4828", "name": "ERGT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_549260", "map_id": "CHEBI:4828", "name": "ERGT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051273", "map_id": "E1BEU0", "name": "SLC22A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000013203", "map_id": "ENSBTAT00000013203", "name": "SLC22A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051283", "map_id": "none", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10051269", "map_id": "none", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_549264", "map_id": "none", "name": "OCT1 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:42820", "map_id": "CHEBI:42820", "name": "CHEBI:42820", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_549250", "map_id": "none", "name": "OCT1 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051286", "map_id": "none", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10067993", "map_id": "none", "name": "DBC1 binds SIRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10048710", "map_id": "F1MQB8", "name": "SIRT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10067989", "map_id": "E1B9H3", "name": "phospho-CCAR2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000007194", "map_id": "ENSBTAT00000007194", "name": "CCAR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067991", "map_id": "none", "name": "p-T454-DBC1:SIRT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B9H3", "map_id": "E1B9H3", "name": "CCAR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071241", "map_id": "none", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071123", "map_id": "none", "name": "HSP70s:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10071232", "map_id": "none", "name": "HSP70s:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10071238", "map_id": "none", "name": "DNAJB1,B6,C2,C7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1RMH9", "map_id": "Q1RMH9", "name": "DNAJC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004925", "map_id": "ENSBTAT00000004925", "name": "DNAJC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7H0", "map_id": "F1N7H0", "name": "DNAJC7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003437", "map_id": "ENSBTAT00000003437", "name": "DNAJC7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068008", "map_id": "none", "name": "DBC1 is phosphorylated by ATM/ART", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10067995", "map_id": "E1B9H3", "name": "CCAR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10068005", "map_id": "none", "name": "ATM/ATR kinase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BEI6", "map_id": "E1BEI6", "name": "ATM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8V1", "map_id": "A0A3Q1M8V1", "name": "ATR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066572", "map_id": "ENSBTAT00000066572", "name": "ATR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071208", "map_id": "none", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10071171", "map_id": "none", "name": "Hikeshi:HSP70s:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q56JY0", "map_id": "Q56JY0", "name": "HIKESHI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026632", "map_id": "ENSBTAT00000026632", "name": "HIKESHI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071169", "map_id": "Q56JY0", "name": "HIKESHI", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10071195", "map_id": "none", "name": "HSP70s:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10071205", "map_id": "none", "name": "DNAJB1,B6,C2,C7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10071313", "map_id": "none", "name": "HSP110s exchange ATP for ADP on HSP70s:ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071304", "map_id": "none", "name": "HSP70 NEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0IIM3", "map_id": "Q0IIM3", "name": "HSPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006600", "map_id": "ENSBTAT00000006600", "name": "HSPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148J7", "map_id": "Q148J7", "name": "BAG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023720", "map_id": "ENSBTAT00000023720", "name": "BAG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBG5", "map_id": "Q3ZBG5", "name": "BAG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007039", "map_id": "ENSBTAT00000007039", "name": "BAG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MIU2", "map_id": "F1MIU2", "name": "BAG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018131", "map_id": "ENSBTAT00000018131", "name": "BAG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MSS9", "map_id": "F1MSS9", "name": "BAG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017468", "map_id": "ENSBTAT00000017468", "name": "BAG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071311", "map_id": "none", "name": "ST13 tetramer", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MQM3", "map_id": "A0A3Q1MQM3", "name": "ST13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074682", "map_id": "ENSBTAT00000074682", "name": "ST13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071127", "map_id": "none", "name": "Hikeshi binds HSP70s:ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071069", "map_id": "Q56JY0", "name": "HIKESHI", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071125", "map_id": "none", "name": "Hikeshi:HSP70s:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10092312", "map_id": "none", "name": "CO binds to Cytochrome c oxidase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_9709326", "map_id": "CHEBI:17245", "name": "CO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10040636", "map_id": "none", "name": "HMOX1 dimer, HMOX2 cleave heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189385", "map_id": "CHEBI:17245", "name": "CO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189396", "map_id": "CHEBI:17033", "name": "BV", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040633", "map_id": "F1MTY9", "name": "HMOX2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10047807", "map_id": "none", "name": "Fatty acid ligands activate PPARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10047799", "map_id": "none", "name": "FABP1:ligands of PPARA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P80425", "map_id": "P80425", "name": "FABP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024032", "map_id": "ENSBTAT00000024032", "name": "FABP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047793", "map_id": "none", "name": "Coactivators of PPARalpha", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0II51", "map_id": "Q0II51", "name": "SMARCD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078286", "map_id": "ENSBTAT00000078286", "name": "SMARCD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N1K9", "map_id": "F1N1K9", "name": "TGS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007749", "map_id": "ENSBTAT00000007749", "name": "TGS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_159151", "map_id": "CHEBI:16990", "name": "BIL", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10047777", "map_id": "none", "name": "PPARA:RXRA Corepressor complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MTR3", "map_id": "F1MTR3", "name": "SIN3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013167", "map_id": "ENSBTAT00000013167", "name": "SIN3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA13", "map_id": "Q5EA13", "name": "PPARA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068423", "map_id": "ENSBTAT00000068423", "name": "PPARA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10047797", "map_id": "P80425", "name": "FABP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10047805", "map_id": "none", "name": "PPARA:RXRA Coactivator complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10047771", "map_id": "none", "name": "Corepressors of PPARalpha", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10092308", "map_id": "none", "name": "CO binds to free ferrohemoglobin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10092310", "map_id": "none", "name": "H2O2 reduces MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10067416", "map_id": "none", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067409", "map_id": "none", "name": "CCS:Zn2+:2xCu1+:SOD1:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BE86", "map_id": "E1BE86", "name": "CCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005683", "map_id": "ENSBTAT00000005683", "name": "CCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_3299744", "map_id": "CHEBI:49552", "name": "Cu1+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10067413", "map_id": "none", "name": "CCS:Zn2+:Cu1+ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10067395", "map_id": "none", "name": "2xHC-SOD1:Zn2+:Cu2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_209799", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10056408", "map_id": "none", "name": "NOX2 generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_1222424", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10056405", "map_id": "none", "name": "NOX2 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10076891", "map_id": "none", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696199", "map_id": "CHEBI:15883", "name": "GP4G", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5696194", "map_id": "CHEBI:17345", "name": "GMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076888", "map_id": "Q29RJ1", "name": "NUDT2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000045076", "map_id": "ENSBTAT00000045076", "name": "NUDT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087866", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068573", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067388", "map_id": "none", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10067385", "map_id": "none", "name": "SOD3 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F6R4N7", "map_id": "F6R4N7", "name": "SOD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018580", "map_id": "ENSBTAT00000018580", "name": "SOD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068575", "map_id": "none", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067407", "map_id": "none", "name": "SOD1:Zn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10068571", "map_id": "none", "name": "CCS:Zn2+:2xCu1+ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10069854", "map_id": "none", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10069852", "map_id": "none", "name": "SOD3 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10067731", "map_id": "none", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_1655882", "map_id": "CHEBI:17858", "name": "GSSG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10067728", "map_id": "none", "name": "GSR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BKZ1", "map_id": "E1BKZ1", "name": "GSR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009363", "map_id": "ENSBTAT00000009363", "name": "GSR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080786", "map_id": "none", "name": "GPX5,6 reduce H2O2 to H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_1247892", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_3341331", "map_id": "CHEBI:17858", "name": "GSSG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10080783", "map_id": "none", "name": "GPX5, (GPX6)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1M7E3", "map_id": "A0A3Q1M7E3", "name": "LOC112441537", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068263", "map_id": "ENSBTAT00000068263", "name": "LOC112441537", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCF5", "map_id": "F1MCF5", "name": "GPX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015939", "map_id": "ENSBTAT00000015939", "name": "GPX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067735", "map_id": "none", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_3341308", "map_id": "CHEBI:18421", "name": "O2-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189461", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "reaction_10034166", "map_id": "none", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034163", "map_id": "none", "name": "GSR-2:FAD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10067722", "map_id": "none", "name": "PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10067702", "map_id": "Q95108", "name": "TXN2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000000014", "map_id": "ENSBTAT00000000014", "name": "TXN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1614617", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10067705", "map_id": "Q95108", "name": "TXN2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10067719", "map_id": "none", "name": "PRDX3,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P35705", "map_id": "P35705", "name": "PRDX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011505", "map_id": "ENSBTAT00000011505", "name": "PRDX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9BGI1", "map_id": "Q9BGI1", "name": "PRDX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011403", "map_id": "ENSBTAT00000011403", "name": "PRDX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10068716", "map_id": "none", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189481", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10068713", "map_id": "none", "name": "SOD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "reaction_10067375", "map_id": "none", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3299683", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10067372", "map_id": "none", "name": "SOD2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1BHL1", "map_id": "E1BHL1", "name": "SOD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008569", "map_id": "ENSBTAT00000008569", "name": "SOD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067744", "map_id": "none", "name": "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067741", "map_id": "none", "name": "PRDX6:GSTP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10068578", "map_id": "none", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3697881", "map_id": "CHEBI:25941", "name": "Peroxynitrite", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_3697842", "map_id": "CHEBI:16301", "name": "Nitrite", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10067717", "map_id": "Q9BGI1", "name": "PRDX5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10067398", "map_id": "none", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10066873", "map_id": "none", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066855", "map_id": "none", "name": "phospho-p38 MAPK: MAPKAPK5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066779", "map_id": "none", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066768", "map_id": "none", "name": "CDKN2A Gene:H3K27Me3-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066770", "map_id": "none", "name": "CDKN2A Gene:Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066776", "map_id": "none", "name": "KDM6B:Fe2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066876", "map_id": "none", "name": "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044327", "map_id": "none", "name": "PRC2 (EZH2) Core", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066832", "map_id": "none", "name": "PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066828", "map_id": "none", "name": "PRC1.4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6QLQ0", "map_id": "A6QLQ0", "name": "RNF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000025", "map_id": "ENSBTAT00000000025", "name": "RNF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LR89", "map_id": "A0A3Q1LR89", "name": "RING1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086711", "map_id": "ENSBTAT00000086711", "name": "RING1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFG7", "map_id": "E1BFG7", "name": "PHC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006041", "map_id": "ENSBTAT00000006041", "name": "PHC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MBA7", "map_id": "A0A3Q1MBA7", "name": "PHC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073548", "map_id": "ENSBTAT00000073548", "name": "PHC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32KX7", "map_id": "Q32KX7", "name": "BMI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073960", "map_id": "ENSBTAT00000073960", "name": "BMI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKU2", "map_id": "F1MKU2", "name": "CBX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061326", "map_id": "ENSBTAT00000061326", "name": "CBX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MDR6", "map_id": "A0A3Q1MDR6", "name": "CBX4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076497", "map_id": "ENSBTAT00000076497", "name": "CBX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCA3", "map_id": "A0A3Q1MCA3", "name": "CBX8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074913", "map_id": "ENSBTAT00000074913", "name": "CBX8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066830", "map_id": "none", "name": "CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066857", "map_id": "none", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066853", "map_id": "none", "name": "p38 MAPK:MAPKAPK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066786", "map_id": "none", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066783", "map_id": "F1MXH6", "name": "MAP3K5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000011949", "map_id": "ENSBTAT00000011949", "name": "MAP3K5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088964", "map_id": "none", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066774", "map_id": "G3N346", "name": "KDM6B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_111793", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10076298", "map_id": "none", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074450", "map_id": "none", "name": "DNA DSBs:MRN:Ac-K3016-ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MIR9", "map_id": "A0A3Q1MIR9", "name": "KAT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083355", "map_id": "ENSBTAT00000083355", "name": "KAT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X6W2", "map_id": "G3X6W2", "name": "RAD50", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014945", "map_id": "ENSBTAT00000014945", "name": "RAD50", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6PSE2", "map_id": "F6PSE2", "name": "NBN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017598", "map_id": "ENSBTAT00000017598", "name": "NBN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076295", "map_id": "none", "name": "DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074429", "map_id": "none", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074417", "map_id": "none", "name": "Shortened telomere:MRN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074425", "map_id": "none", "name": "ATM dimer:KAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074427", "map_id": "none", "name": "Shortened telomere:MRN:ATM dimer:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074431", "map_id": "none", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035718", "map_id": "none", "name": "MRN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_3785706", "map_id": "none", "name": "Shortened telomere", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10074446", "map_id": "none", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074438", "map_id": "none", "name": "Shortened telomere:MRN:Ac-K3016-ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074443", "map_id": "none", "name": "Shortened telomere:MRN:KAT5:p-S1981,Ac-K3016-ATM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10078369", "map_id": "none", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10074453", "map_id": "none", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074448", "map_id": "none", "name": "DNA DSBs:MRN:ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10069684", "map_id": "none", "name": "EP400 binds CDKN1A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069680", "map_id": "none", "name": "p-S15-TP53 Tetramer:CDKN1A Gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10069676", "map_id": "F1MLB1", "name": "EP400", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000027216", "map_id": "ENSBTAT00000027216", "name": "EP400", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069682", "map_id": "none", "name": "EP400:p-S15-TP53 Tetramer:CDKN1A Gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MLB1", "map_id": "F1MLB1", "name": "EP400", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076343", "map_id": "none", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10068852", "map_id": "none", "name": "DNA DSBs:MRN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10068854", "map_id": "none", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_75165", "map_id": "none", "name": "DNA double-strand break ends", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10066630", "map_id": "none", "name": "Phosphorylated ERF translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066626", "map_id": "F1MET2", "name": "phospho-ERF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000000437", "map_id": "ENSBTAT00000000437", "name": "phospho-ERF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066628", "map_id": "F1MET2", "name": "phospho-ERF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091401", "map_id": "none", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091329", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10091333", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10091399", "map_id": "none", "name": "FLCN:FNIP1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3B7L5", "map_id": "Q3B7L5", "name": "FLCN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010532", "map_id": "ENSBTAT00000010532", "name": "FLCN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MS15", "map_id": "A0A3Q1MS15", "name": "FNIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083520", "map_id": "ENSBTAT00000083520", "name": "FNIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NF19", "map_id": "A0A3Q1NF19", "name": "FNIP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067422", "map_id": "ENSBTAT00000067422", "name": "FNIP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091336", "map_id": "none", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "reaction_10091354", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091344", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10091342", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10091338", "map_id": "none", "name": "SLC38A9:L-Arg", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10091356", "map_id": "none", "name": "v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091340", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10091404", "map_id": "none", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091358", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10091360", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10091365", "map_id": "none", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091362", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10091351", "map_id": "none", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10091349", "map_id": "E1BB46", "name": "SH3BP4", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000087052", "map_id": "ENSBTAT00000087052", "name": "SH3BP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073481", "map_id": "none", "name": "MT2A binds copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073456", "map_id": "none", "name": "Homologues of MT2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M6Y6", "map_id": "A0A3Q1M6Y6", "name": "MT1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069619", "map_id": "ENSBTAT00000069619", "name": "MT1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P68301", "map_id": "P68301", "name": "MT2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034373", "map_id": "ENSBTAT00000034373", "name": "MT2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073479", "map_id": "none", "name": "MT2A:10Cu1+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073464", "map_id": "none", "name": "MT3 exchanges zinc for copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073444", "map_id": "none", "name": "MT3:7Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P37359", "map_id": "P37359", "name": "MT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022460", "map_id": "ENSBTAT00000022460", "name": "MT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073462", "map_id": "none", "name": "MT3:4Zn2+:4Cu+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073468", "map_id": "none", "name": "MT3 binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073442", "map_id": "P37359", "name": "MT3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1132098", "map_id": "CHEBI:48775", "name": "Cd2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10073466", "map_id": "none", "name": "MT3:7Cd2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073460", "map_id": "none", "name": "MT2A binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10073458", "map_id": "none", "name": "MT2A:7Cd2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10073446", "map_id": "none", "name": "MT3 binds zinc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10075304", "map_id": "none", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075297", "map_id": "none", "name": "DNA DSB:MRN:RBBP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1NLY2", "map_id": "A0A3Q1NLY2", "name": "RBBP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085498", "map_id": "ENSBTAT00000085498", "name": "RBBP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075301", "map_id": "none", "name": "Microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30555", "map_id": "CHEBI:16516", "name": "dNTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10075323", "map_id": "none", "name": "MRN recruits LIG3:XRCC1 to MMEJ sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036900", "map_id": "none", "name": "LIG3:XRCC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N2F9", "map_id": "F1N2F9", "name": "XRCC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081405", "map_id": "ENSBTAT00000081405", "name": "XRCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LF81", "map_id": "A0A3Q1LF81", "name": "LIG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075817", "map_id": "ENSBTAT00000075817", "name": "LIG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075316", "map_id": "none", "name": "Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075321", "map_id": "none", "name": "Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:LIG3:XRCC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075306", "map_id": "none", "name": "MRN complex binds RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074778", "map_id": "none", "name": "RBBP8 homotetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075326", "map_id": "none", "name": "LIG3 ligates remaining SSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5687670", "map_id": "none", "name": "dsDNA with base substitutions and inter-MMEJ deletion", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10075319", "map_id": "none", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075312", "map_id": "none", "name": "Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q58DH8", "map_id": "Q58DH8", "name": "FEN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000071", "map_id": "ENSBTAT00000000071", "name": "FEN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_68454", "map_id": "none", "name": "Flap", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10036890", "map_id": "Q58DH8", "name": "FEN1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10086350", "map_id": "none", "name": "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_189227", "map_id": "none", "name": "Gal, Glc", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_188995", "map_id": "CHEBI:17118", "name": "Gal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_189254", "map_id": "none", "name": "Gal, Glc", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10086347", "map_id": "F1MD24", "name": "SLC5A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000084455", "map_id": "ENSBTAT00000084455", "name": "SLC5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057350", "map_id": "none", "name": "Activation of ATP sensitive Potassium channels in neuroendocrine cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057347", "map_id": "none", "name": "ATP sensitive K+ channels (SUR1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q2KHY6", "map_id": "Q2KHY6", "name": "KCNJ8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003307", "map_id": "ENSBTAT00000003307", "name": "KCNJ8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDS4", "map_id": "A2VDS4", "name": "KCNJ11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021523", "map_id": "ENSBTAT00000021523", "name": "KCNJ11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKR6", "map_id": "E1BKR6", "name": "ABCC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046676", "map_id": "ENSBTAT00000046676", "name": "ABCC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057399", "map_id": "none", "name": "Activation of Potassium transport channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057396", "map_id": "none", "name": "KIR 1.1 homotetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1N684", "map_id": "A0A3Q1N684", "name": "KCNJ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081253", "map_id": "ENSBTAT00000081253", "name": "KCNJ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033473", "map_id": "none", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10033469", "map_id": "A0A3Q1MVB0", "name": "phospho-CDC6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10033471", "map_id": "A0A3Q1MVB0", "name": "phospho-CDC6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10084497", "map_id": "none", "name": "RNA demethylases demethylate N6-methyladenosine RNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_8857725", "map_id": "CHEBI:21891", "name": "N6-methyladenosine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_8857850", "map_id": "CHEBI:16335", "name": "adenosine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10084494", "map_id": "none", "name": "RNA demethylases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N5P9", "map_id": "A0A3Q1N5P9", "name": "FTO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081168", "map_id": "ENSBTAT00000081168", "name": "FTO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ48", "map_id": "A0A452DJ48", "name": "ALKBH5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034976", "map_id": "ENSBTAT00000034976", "name": "ALKBH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090466", "map_id": "none", "name": "ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025155", "map_id": "CHEBI:65136", "name": "DPAn-6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9025151", "map_id": "none", "name": "17(S)-HDPAn-6, 10(S),17(S)-diHDPAn-6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138674", "map_id": "CHEBI:138674", "name": "CHEBI:138674", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138673", "map_id": "CHEBI:138673", "name": "CHEBI:138673", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064558", "map_id": "P27479", "name": "ALOX15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090468", "map_id": "none", "name": "ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025960", "map_id": "CHEBI:140218", "name": "14(S)-HDPAn-6", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090477", "map_id": "none", "name": "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9026407", "map_id": "CHEBI:91274", "name": "13(R)-HDPAn-3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090470", "map_id": "none", "name": "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9026047", "map_id": "CHEBI:140226", "name": "17(S)-Hp-DPAn-3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090472", "map_id": "none", "name": "ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9026293", "map_id": "CHEBI:140222", "name": "14(S)-Hp-DPAn-3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090474", "map_id": "none", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025012", "map_id": "CHEBI:140220", "name": "14(S)-Hp-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9026307", "map_id": "CHEBI:140200", "name": "13,14(S)-epoxy-DPAn-3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10052888", "map_id": "none", "name": "holoTF:TFRC dimer translocates from plasma membrane to endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10052876", "map_id": "none", "name": "holoTF:TFRC dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BIG6", "map_id": "E1BIG6", "name": "TFRC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046421", "map_id": "ENSBTAT00000046421", "name": "TFRC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052886", "map_id": "none", "name": "holoTF:TFRC dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10052923", "map_id": "none", "name": "MCOLN1 transports Fe2+ from endosome lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_917810", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10052920", "map_id": "G3MY82", "name": "MCOLN1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "reaction_10052907", "map_id": "none", "name": "apoTF:TFRC dimer translocates from endosome membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052903", "map_id": "none", "name": "apoTF:TFRC dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10052905", "map_id": "none", "name": "apoTF:TFRC dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052925", "map_id": "none", "name": "TFRC dimer binds 2xholoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10052874", "map_id": "none", "name": "holoTF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10052872", "map_id": "none", "name": "TFRC dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10052909", "map_id": "none", "name": "Fe3+ dissociates from holoTF:TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171907", "compartment_display": "endosome lumen" }, { "id": "reaction_10052911", "map_id": "none", "name": "apo-Transferrin dissociates from the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane" }, { "id": "reaction_10076099", "map_id": "none", "name": "HFE binds TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10076095", "map_id": "Q5EEZ1", "name": "HFE", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000017371", "map_id": "ENSBTAT00000017371", "name": "HFE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076097", "map_id": "none", "name": "HFE:TFRC dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q5EEZ1", "map_id": "Q5EEZ1", "name": "HFE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052901", "map_id": "none", "name": "STEAP3-like proteins reduce Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171907", "compartment_display": "endosome lumen" }, { "id": "species_917882", "map_id": "CHEBI:10545", "name": "e-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "species_10052898", "map_id": "none", "name": "STEAP3-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10036076", "map_id": "none", "name": "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036050", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBP80:CBP20:SLBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036052", "map_id": "none", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036048", "map_id": "A0A3Q1N0Z1", "name": "SLBP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10036044", "map_id": "none", "name": "Capped Intronless Histone pre-mRNA:CBC complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10085967", "map_id": "none", "name": "SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8876310", "map_id": "none", "name": "LACT, PYR, NCA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8876304", "map_id": "none", "name": "LACT, PYR, NCA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10085964", "map_id": "A7MBD8", "name": "SLC5A12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000029140", "map_id": "ENSBTAT00000029140", "name": "SLC5A12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048768", "map_id": "none", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_425425", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10048765", "map_id": "F1N207", "name": "SLC26A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000033777", "map_id": "ENSBTAT00000033777", "name": "SLC26A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048740", "map_id": "none", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048737", "map_id": "none", "name": "SLC26 chloride transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BD54", "map_id": "E1BD54", "name": "SLC26A7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045797", "map_id": "ENSBTAT00000045797", "name": "SLC26A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9J2", "map_id": "E1B9J2", "name": "SLC26A9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001818", "map_id": "ENSBTAT00000001818", "name": "SLC26A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052040", "map_id": "none", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_893599", "map_id": "CHEBI:29750", "name": "3IN-PYRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10052037", "map_id": "none", "name": "PXLP-KYAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6Q816", "map_id": "F6Q816", "name": "KYAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050582", "map_id": "ENSBTAT00000050582", "name": "KYAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064346", "map_id": "none", "name": "IL4I1:FAD oxidises L-Phe to kPPV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_2022135", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2160466", "map_id": "CHEBI:18005", "name": "kPPV", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10064343", "map_id": "none", "name": "IL4I1:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1N191", "map_id": "F1N191", "name": "IL4I1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007580", "map_id": "ENSBTAT00000007580", "name": "IL4I1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033935", "map_id": "none", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71129", "map_id": "CHEBI:20680", "name": "qDHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033932", "map_id": "none", "name": "PCBD1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZBD3", "map_id": "Q3ZBD3", "name": "PCBD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015750", "map_id": "ENSBTAT00000015750", "name": "PCBD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076974", "map_id": "none", "name": "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5359061", "map_id": "CHEBI:17790", "name": "MeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076971", "map_id": "none", "name": "ASRGL1 heterodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q32LE5", "map_id": "Q32LE5", "name": "ASRGL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077904", "map_id": "ENSBTAT00000077904", "name": "ASRGL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033944", "map_id": "none", "name": "homogentisate + O2 => maleylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30337", "map_id": "CHEBI:16169", "name": "HGTA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31135", "map_id": "CHEBI:17105", "name": "4MAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033941", "map_id": "none", "name": "HGD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LS65", "map_id": "A0A3Q1LS65", "name": "HGD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087453", "map_id": "ENSBTAT00000087453", "name": "HGD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033962", "map_id": "none", "name": "fumarylacetoacetate => fumarate + acetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31175", "map_id": "CHEBI:18034", "name": "4FAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29666", "map_id": "CHEBI:13705", "name": "ACA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29586", "map_id": "CHEBI:37154", "name": "FUMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033959", "map_id": "none", "name": "FAH dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MPJ4", "map_id": "A0A3Q1MPJ4", "name": "FAH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072597", "map_id": "ENSBTAT00000072597", "name": "FAH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033953", "map_id": "none", "name": "maleylacetoacetate => fumarylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033950", "map_id": "none", "name": "GSTZ1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10075181", "map_id": "none", "name": "ABL1 phosphorylates RAD52", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035844", "map_id": "none", "name": "RAD52 heptamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A2VE43", "map_id": "A2VE43", "name": "phospho-RAD52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000055617", "map_id": "ENSBTAT00000055617", "name": "phospho-RAD52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075178", "map_id": "none", "name": "p-Y104-RAD52 heptamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075170", "map_id": "A0A3Q1LI98", "name": "phospho-ABL1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10035846", "map_id": "none", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035842", "map_id": "A2VE43", "name": "RAD52", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10040183", "map_id": "none", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10040167", "map_id": "A4IFH4", "name": "GINS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000026619", "map_id": "ENSBTAT00000026619", "name": "GINS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040179", "map_id": "A2VE40", "name": "GINS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000022773", "map_id": "ENSBTAT00000022773", "name": "GINS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040175", "map_id": "Q08E12", "name": "GINS3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000012322", "map_id": "ENSBTAT00000012322", "name": "GINS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040171", "map_id": "E1BC42", "name": "GINS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000061540", "map_id": "ENSBTAT00000061540", "name": "GINS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040181", "map_id": "none", "name": "GINS complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BC42", "map_id": "E1BC42", "name": "GINS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E12", "map_id": "Q08E12", "name": "GINS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VE40", "map_id": "A2VE40", "name": "GINS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4IFH4", "map_id": "A4IFH4", "name": "GINS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033504", "map_id": "none", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_68452", "map_id": "none", "name": "Okazaki fragment", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_69172", "map_id": "none", "name": "ligated okazaki fragment", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10038904", "map_id": "none", "name": "Association of mTERF with the termination sequence", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10038900", "map_id": "G3N2I6", "name": "MTERF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000063305", "map_id": "ENSBTAT00000063305", "name": "MTERF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_164569", "map_id": "none", "name": "mitochondrial transcription termination sequence", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10038902", "map_id": "none", "name": "mTERF:mitochondrial transcription termination sequence", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "G3N2I6", "map_id": "G3N2I6", "name": "MTERF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040864", "map_id": "none", "name": "Synthesis of Cx43", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10040862", "map_id": "P18246", "name": "GJA1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10055833", "map_id": "none", "name": "Kinesin-13 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055577", "map_id": "F1N0Y3", "name": "KIF2B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023059", "map_id": "ENSBTAT00000023059", "name": "KIF2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055579", "map_id": "none", "name": "KIF2B dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N0Y3", "map_id": "F1N0Y3", "name": "KIF2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055515", "map_id": "none", "name": "Kinesin-1 is a heterotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055511", "map_id": "none", "name": "Kinesin-1 heavy chain", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10055501", "map_id": "none", "name": "KLC1,KLC2,KLC3,KLC4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055645", "map_id": "none", "name": "Kinesins move along microtubules consuming ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055643", "map_id": "none", "name": "Kinesins:microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BF29", "map_id": "E1BF29", "name": "KIF11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012347", "map_id": "ENSBTAT00000012347", "name": "KIF11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG49", "map_id": "E1BG49", "name": "CENPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011898", "map_id": "ENSBTAT00000011898", "name": "CENPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MCP5", "map_id": "F1MCP5", "name": "KIF4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076641", "map_id": "ENSBTAT00000076641", "name": "KIF4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MG61", "map_id": "A0A3Q1MG61", "name": "KIF22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076936", "map_id": "ENSBTAT00000076936", "name": "KIF22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BC41", "map_id": "E1BC41", "name": "KIF15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060943", "map_id": "ENSBTAT00000060943", "name": "KIF15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055823", "map_id": "none", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055559", "map_id": "E1BF29", "name": "KIF11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055561", "map_id": "none", "name": "Kinesin-5 homotetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055647", "map_id": "none", "name": "Kinesins bind microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055641", "map_id": "none", "name": "Kinesins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055827", "map_id": "none", "name": "Chromokinesins form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055825", "map_id": "none", "name": "Chromokinesin monomers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10055555", "map_id": "none", "name": "Chromokinesin dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055829", "map_id": "none", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055565", "map_id": "E1BG49", "name": "CENPE", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055567", "map_id": "none", "name": "CENP-E dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055831", "map_id": "none", "name": "Kinesin-3 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055533", "map_id": "E1BKE3", "name": "KIF3A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055535", "map_id": "none", "name": "KIF3A dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090460", "map_id": "none", "name": "ALOX15 oxidises 17(S)-Hp-DHA to PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024012", "map_id": "CHEBI:136113", "name": "17(S)-Hp-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024883", "map_id": "CHEBI:138653", "name": "PDX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090386", "map_id": "none", "name": "ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024522", "map_id": "CHEBI:138590", "name": "17(R)-Hp-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024893", "map_id": "CHEBI:140192", "name": "17R(16)-epoxy-DHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090708", "map_id": "none", "name": "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_9024886", "map_id": "CHEBI:138655", "name": "(N)PD1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9037755", "map_id": "CHEBI:140243", "name": "22-OH-(N)PD1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090705", "map_id": "none", "name": "CYP1A1, CYP1A2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10091753", "map_id": "none", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9648300", "map_id": "none", "name": "chlorpromazine", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084440", "map_id": "none", "name": "AP-2 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LVF9", "map_id": "A0A3Q1LVF9", "name": "AP2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074327", "map_id": "ENSBTAT00000074327", "name": "AP2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DS7", "map_id": "Q08DS7", "name": "AP2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076585", "map_id": "ENSBTAT00000076585", "name": "AP2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCG7", "map_id": "A0A3Q1MCG7", "name": "AP2M1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050604", "map_id": "ENSBTAT00000050604", "name": "AP2M1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085164", "map_id": "none", "name": "AP2:chlorpromazine", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084824", "map_id": "none", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084753", "map_id": "none", "name": "STON2,1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MWJ5", "map_id": "A0A3Q1MWJ5", "name": "STON2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082605", "map_id": "ENSBTAT00000082605", "name": "STON2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075931", "map_id": "E1BJ64", "name": "NEDD8(1-88)", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084779", "map_id": "none", "name": "NEDD8-STONs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10085116", "map_id": "none", "name": "ARRB bind GPCRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10085112", "map_id": "none", "name": "ARRB-binding GPCRs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10085114", "map_id": "none", "name": "ARRB:ARRB-binding GPCRs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085166", "map_id": "none", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10085160", "map_id": "none", "name": "AP-2 cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P11456", "map_id": "P11456", "name": "M6PR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067687", "map_id": "ENSBTAT00000067687", "name": "M6PR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK36", "map_id": "E1BK36", "name": "SLC18A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019955", "map_id": "ENSBTAT00000019955", "name": "SLC18A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJK4", "map_id": "F1MJK4", "name": "CD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037742", "map_id": "ENSBTAT00000037742", "name": "CD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32L97", "map_id": "Q32L97", "name": "VAMP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071023", "map_id": "ENSBTAT00000071023", "name": "VAMP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPN6", "map_id": "A0A3S5ZPN6", "name": "SCARB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014549", "map_id": "ENSBTAT00000014549", "name": "SCARB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085162", "map_id": "none", "name": "AP-2:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085134", "map_id": "none", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085126", "map_id": "none", "name": "UBQLN2,1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G5E628", "map_id": "G5E628", "name": "UBQLN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029117", "map_id": "ENSBTAT00000029117", "name": "UBQLN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085130", "map_id": "A0A3Q1MSK9", "name": "EPN2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000084618", "map_id": "ENSBTAT00000084618", "name": "EPN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085132", "map_id": "none", "name": "UNQLNs:UIM proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MSK9", "map_id": "A0A3Q1MSK9", "name": "EPN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085264", "map_id": "none", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10085260", "map_id": "none", "name": "PICALMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NKA6", "map_id": "A0A3Q1NKA6", "name": "PICALM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070874", "map_id": "ENSBTAT00000070874", "name": "PICALM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085262", "map_id": "none", "name": "PICALM:VAMP2,3,8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084819", "map_id": "none", "name": "NEDD8-STON binds TOR1 hexamer and COP9 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084793", "map_id": "none", "name": "TOR1 hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MQM0", "map_id": "A0A3Q1MQM0", "name": "TOR1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080374", "map_id": "ENSBTAT00000080374", "name": "TOR1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084817", "map_id": "none", "name": "NEDD8-STONs:TOR1 hexamer:COP9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084757", "map_id": "none", "name": "STON2 binds SYT proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084743", "map_id": "none", "name": "SYT dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LZP6", "map_id": "A0A3Q1LZP6", "name": "SYT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081053", "map_id": "ENSBTAT00000081053", "name": "SYT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LXE7", "map_id": "A0A3Q1LXE7", "name": "SYT9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080553", "map_id": "ENSBTAT00000080553", "name": "SYT9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084755", "map_id": "none", "name": "STON2,1:SYT dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084822", "map_id": "none", "name": "COP9 and TOR1 deneddylate STON2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10089048", "map_id": "none", "name": "Myoglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089044", "map_id": "none", "name": "MB:ferroheme b", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P02192", "map_id": "P02192", "name": "MB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084629", "map_id": "ENSBTAT00000084629", "name": "MB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089046", "map_id": "none", "name": "MB:ferroheme b:O2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089058", "map_id": "none", "name": "Neuroglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089054", "map_id": "none", "name": "NGB:ferroheme b", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q6WZ19", "map_id": "Q6WZ19", "name": "NGB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021661", "map_id": "ENSBTAT00000021661", "name": "NGB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089056", "map_id": "none", "name": "NGB:ferroheme b:O2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10089060", "map_id": "none", "name": "Neuroglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10089062", "map_id": "none", "name": "Myoglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10049869", "map_id": "none", "name": "RhCG mediates ammonium efflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_140912", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049625", "map_id": "A0A3Q1M0T1", "name": "RHCG", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000080155", "map_id": "ENSBTAT00000080155", "name": "RHCG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049628", "map_id": "none", "name": "RhCG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10049871", "map_id": "none", "name": "RhBG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049632", "map_id": "Q95M77", "name": "RHBG", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000050191", "map_id": "ENSBTAT00000050191", "name": "RHBG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049635", "map_id": "none", "name": "RhBG mediates ammonium effflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10049371", "map_id": "none", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_435347", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049368", "map_id": "A0A3Q1MRJ4", "name": "SLC11A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000068742", "map_id": "ENSBTAT00000068742", "name": "SLC11A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049402", "map_id": "none", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_437295", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049399", "map_id": "A0A3Q1MPH1", "name": "SLC31A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000072292", "map_id": "ENSBTAT00000072292", "name": "SLC31A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049378", "map_id": "none", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049375", "map_id": "E1BN60", "name": "SLC30A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014489", "map_id": "ENSBTAT00000014489", "name": "SLC30A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088912", "map_id": "none", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29418", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_266099", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10088909", "map_id": "G3X6F6", "name": "SLC30A10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005787", "map_id": "ENSBTAT00000005787", "name": "SLC30A10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049358", "map_id": "none", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_446589", "map_id": "none", "name": "MATE substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:8428", "map_id": "CHEBI:8428", "name": "CHEBI:8428", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_446597", "map_id": "none", "name": "MATE substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10049355", "map_id": "A0A3Q1MWZ9", "name": "SLC47A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000074816", "map_id": "ENSBTAT00000074816", "name": "SLC47A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049060", "map_id": "none", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429130", "map_id": "CHEBI:17268", "name": "Ins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049057", "map_id": "E1BML6", "name": "SLC2A13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000061504", "map_id": "ENSBTAT00000061504", "name": "SLC2A13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049078", "map_id": "none", "name": "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429652", "map_id": "none", "name": "Inositols transported by SMIT2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:27372", "map_id": "CHEBI:27372", "name": "CHEBI:27372", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429648", "map_id": "none", "name": "Inositols transported by SMIT2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10049075", "map_id": "A0A452DHY8", "name": "SLC5A11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000004510", "map_id": "ENSBTAT00000004510", "name": "SLC5A11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049592", "map_id": "none", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049589", "map_id": "A6QLU4", "name": "SLC6A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000035184", "map_id": "ENSBTAT00000035184", "name": "SLC6A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049613", "map_id": "none", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_444154", "map_id": "none", "name": "Biogenic amines transported by VMAT1/2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_444152", "map_id": "none", "name": "Biogenic amines transported by VMAT1/2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen", "complex": "true" }, { "id": "species_10049610", "map_id": "F1MBH3", "name": "SLC18A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_374940", "compartment_display": "clathrin-sculpted monoamine transport vesicle membrane", "complex": "false" }, { "id": "ENSBTAT00000045811", "map_id": "ENSBTAT00000045811", "name": "SLC18A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049599", "map_id": "none", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049596", "map_id": "A0A3Q1NLB0", "name": "SLC6A9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000087022", "map_id": "ENSBTAT00000087022", "name": "SLC6A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049319", "map_id": "none", "name": "SOAT can transport taurolithocholate-3-sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_433120", "map_id": "CHEBI:17864", "name": "taurolithocholate sulfate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_176483", "map_id": "CHEBI:17864", "name": "taurolithocholate sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049316", "map_id": "A0A452DJI9", "name": "SLC10A6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000066284", "map_id": "ENSBTAT00000066284", "name": "SLC10A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049606", "map_id": "none", "name": "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_432019", "map_id": "CHEBI:16199", "name": "Urea", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049603", "map_id": "E1BP25", "name": "SLC14A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000002712", "map_id": "ENSBTAT00000002712", "name": "SLC14A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049080", "map_id": "none", "name": "SLC5A6 transports vitamins from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429605", "map_id": "none", "name": "vitamins transported by SMVT", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:16494", "map_id": "CHEBI:16494", "name": "CHEBI:16494", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429627", "map_id": "none", "name": "vitamins transported by SMVT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051577", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10051574", "map_id": "E1BEH8", "name": "SLC35B4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "ENSBTAT00000004376", "map_id": "ENSBTAT00000004376", "name": "SLC35B4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051580", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_742353", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10051587", "map_id": "none", "name": "SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_744239", "map_id": "CHEBI:17345", "name": "guanosine 5'-monophosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_744233", "map_id": "CHEBI:15820", "name": "GDP-Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10039874", "map_id": "none", "name": "SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_158601", "map_id": "CHEBI:17200", "name": "UDP-GlcA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3499326", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_174384", "map_id": "CHEBI:17200", "name": "UDP-GlcA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10039871", "map_id": "none", "name": "SLC35D1 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A2VE55", "map_id": "A2VE55", "name": "SLC35D2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051899", "map_id": "none", "name": "SLCO4C1 mediates the transport of digoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_879521", "map_id": "CHEBI:4551", "name": "DIGX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_879517", "map_id": "CHEBI:4551", "name": "DIGX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10051896", "map_id": "F1N3T5", "name": "SLCO4C1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10051866", "map_id": "none", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_879603", "map_id": "none", "name": "T3,T4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_879628", "map_id": "none", "name": "T3,T4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051863", "map_id": "none", "name": "SLCOs, SLC16A2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BC23", "map_id": "E1BC23", "name": "SLCO1C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026117", "map_id": "ENSBTAT00000026117", "name": "SLCO1C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPV8", "map_id": "E1BPV8", "name": "SLCO4A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021795", "map_id": "ENSBTAT00000021795", "name": "SLCO4A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MM56", "map_id": "F1MM56", "name": "SLC16A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003345", "map_id": "ENSBTAT00000003345", "name": "SLC16A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MYV0", "map_id": "F1MYV0", "name": "SLCO1B3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030217", "map_id": "ENSBTAT00000030217", "name": "SLCO1B3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051843", "map_id": "none", "name": "SLCO2A1 transports PGT substrates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_879566", "map_id": "none", "name": "PGT substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:15544", "map_id": "CHEBI:15544", "name": "CHEBI:15544", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_879614", "map_id": "none", "name": "PGT substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051840", "map_id": "F1MQ45", "name": "SLCO2A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001747", "map_id": "ENSBTAT00000001747", "name": "SLCO2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091250", "map_id": "none", "name": "SLCO1B1 transports T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051847", "map_id": "F1MYV0", "name": "SLCO1B3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10051879", "map_id": "none", "name": "SLCO3A1 isoform 1 has abroad substrate specificity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051868", "map_id": "none", "name": "SLCO3A1 substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10051872", "map_id": "none", "name": "SLCO3A1 substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051876", "map_id": "Q8HYW2", "name": "SLCO3A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000055950", "map_id": "ENSBTAT00000055950", "name": "SLCO3A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070928", "map_id": "none", "name": "LCNs bind lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10070924", "map_id": "none", "name": "LCNs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LZ62", "map_id": "A0A3Q1LZ62", "name": "LCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084009", "map_id": "ENSBTAT00000084009", "name": "LCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9Y3", "map_id": "E1B9Y3", "name": "LCN12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032576", "map_id": "ENSBTAT00000032576", "name": "LCN12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5229279", "map_id": "CHEBI:18059", "name": "lipids", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10070926", "map_id": "none", "name": "LCNs:lipids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10051892", "map_id": "none", "name": "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_879559", "map_id": "none", "name": "LCFAs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_879544", "map_id": "none", "name": "LCFAs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051889", "map_id": "none", "name": "SLC27A1,4,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0VCQ2", "map_id": "Q0VCQ2", "name": "SLC27A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020526", "map_id": "ENSBTAT00000020526", "name": "SLC27A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQD5", "map_id": "A6QQD5", "name": "SLC27A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044112", "map_id": "ENSBTAT00000044112", "name": "SLC27A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036297", "map_id": "none", "name": "Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179740", "map_id": "none", "name": "ligands of SLC28A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17596", "map_id": "CHEBI:17596", "name": "CHEBI:17596", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16750", "map_id": "CHEBI:16750", "name": "CHEBI:16750", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16704", "map_id": "CHEBI:16704", "name": "CHEBI:16704", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_179741", "map_id": "none", "name": "ligands of SLC28A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036294", "map_id": "F1N428", "name": "SLC28A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021720", "map_id": "ENSBTAT00000021720", "name": "SLC28A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051545", "map_id": "none", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_727774", "map_id": "none", "name": "ligands of SLC29A4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_727737", "map_id": "none", "name": "ligands of SLC29A4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10051542", "map_id": "E1BPT2", "name": "SLC29A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000010219", "map_id": "ENSBTAT00000010219", "name": "SLC29A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071001", "map_id": "none", "name": "ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10070999", "map_id": "none", "name": "ARL2:GTP:ARL2BP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2TA37", "map_id": "Q2TA37", "name": "ARL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002890", "map_id": "ENSBTAT00000002890", "name": "ARL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32PC9", "map_id": "Q32PC9", "name": "ARL2BP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006363", "map_id": "ENSBTAT00000006363", "name": "ARL2BP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070983", "map_id": "none", "name": "ARL2:GTP:ARL2BP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10036283", "map_id": "none", "name": "Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179738", "map_id": "none", "name": "ligands of SLC28A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_83928", "map_id": "CHEBI:17748", "name": "Thy-dRib", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:17562", "map_id": "CHEBI:17562", "name": "CHEBI:17562", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17256", "map_id": "CHEBI:17256", "name": "CHEBI:17256", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_179739", "map_id": "none", "name": "ligands of SLC28A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036280", "map_id": "A0A3Q1LFZ9", "name": "SLC28A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000075356", "map_id": "ENSBTAT00000075356", "name": "SLC28A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051547", "map_id": "none", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10071003", "map_id": "none", "name": "ARL2:GTP binds ARL2BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070997", "map_id": "Q32PC9", "name": "ARL2BP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10070995", "map_id": "none", "name": "ARL2:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070991", "map_id": "none", "name": "ARL2:GTP:ARL2BP binds SLC25A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10070987", "map_id": "P02722", "name": "SLC25A4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000017580", "map_id": "ENSBTAT00000017580", "name": "SLC25A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070989", "map_id": "none", "name": "ARL2:GTP:ARL2BP:SLC25A4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P02722", "map_id": "P02722", "name": "SLC25A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10073838", "map_id": "none", "name": "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "reaction_10036290", "map_id": "none", "name": "Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179737", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_179743", "map_id": "none", "name": "ligands of SLC28A3 & 29A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036287", "map_id": "F1MGR1", "name": "SLC28A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000024328", "map_id": "ENSBTAT00000024328", "name": "SLC28A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036274", "map_id": "none", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179747", "map_id": "none", "name": "ligands of SLC29A2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_83956", "map_id": "CHEBI:16235", "name": "Gua", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29850", "map_id": "CHEBI:17368", "name": "Hyp", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_5635947", "map_id": "CHEBI:16708", "name": "Ade", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "CHEBI:16040", "map_id": "CHEBI:16040", "name": "CHEBI:16040", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_179742", "map_id": "none", "name": "ligands of SLC29A2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036271", "map_id": "A7YY72", "name": "SLC29A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000015948", "map_id": "ENSBTAT00000015948", "name": "SLC29A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036276", "map_id": "none", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10038660", "map_id": "none", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10038657", "map_id": "none", "name": "SLC25A6 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P32007", "map_id": "P32007", "name": "SLC25A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063682", "map_id": "ENSBTAT00000063682", "name": "SLC25A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048747", "map_id": "none", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048744", "map_id": "F1MLZ2", "name": "SLC20A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000010384", "map_id": "ENSBTAT00000010384", "name": "SLC20A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085896", "map_id": "none", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085893", "map_id": "Q08DK4", "name": "SLC25A22", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000001624", "map_id": "ENSBTAT00000001624", "name": "SLC25A22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049083", "map_id": "none", "name": "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10060218", "map_id": "none", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1614584", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10048821", "map_id": "none", "name": "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane" }, { "id": "species_428548", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20600", "compartment_display": "synaptic vesicle", "complex": "false" }, { "id": "species_428614", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20600", "compartment_display": "synaptic vesicle", "complex": "false" }, { "id": "species_10048818", "map_id": "none", "name": "SLC17A6,7,8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane", "complex": "true" }, { "id": "A4FV52", "map_id": "A4FV52", "name": "SLC17A7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009255", "map_id": "ENSBTAT00000009255", "name": "SLC17A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLI1", "map_id": "A6QLI1", "name": "SLC17A6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007935", "map_id": "ENSBTAT00000007935", "name": "SLC17A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BA07", "map_id": "E1BA07", "name": "SLC17A8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001445", "map_id": "ENSBTAT00000001445", "name": "SLC17A8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049173", "map_id": "none", "name": "Passive I- efflux mediated by SMCT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10048601", "map_id": "none", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048598", "map_id": "A0A3Q1MAS3", "name": "SLC12A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000076302", "map_id": "ENSBTAT00000076302", "name": "SLC12A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048618", "map_id": "none", "name": "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048615", "map_id": "none", "name": "SLC12A4,5,6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BCI8", "map_id": "E1BCI8", "name": "SLC12A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024019", "map_id": "ENSBTAT00000024019", "name": "SLC12A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPL9", "map_id": "A0A3S5ZPL9", "name": "SLC12A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018852", "map_id": "ENSBTAT00000018852", "name": "SLC12A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NIV4", "map_id": "A0A3Q1NIV4", "name": "SLC12A7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082311", "map_id": "ENSBTAT00000082311", "name": "SLC12A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048594", "map_id": "none", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048591", "map_id": "F1MS75", "name": "SLC12A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000046583", "map_id": "ENSBTAT00000046583", "name": "SLC12A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048795", "map_id": "none", "name": "Proton-coupled di- and tri-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_428037", "map_id": "none", "name": "Di-peptides/tri-peptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:90799", "map_id": "CHEBI:90799", "name": "CHEBI:90799", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:47923", "map_id": "CHEBI:47923", "name": "CHEBI:47923", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_428026", "map_id": "none", "name": "Di-peptides/tri-peptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10048792", "map_id": "F1MPK7", "name": "SLC15A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000001891", "map_id": "ENSBTAT00000001891", "name": "SLC15A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048802", "map_id": "none", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_427984", "map_id": "none", "name": "Histidine/di-peptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_428003", "map_id": "none", "name": "Histidine/di-peptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:46761", "map_id": "CHEBI:46761", "name": "CHEBI:46761", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048799", "map_id": "F1MYU7", "name": "SLC15A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "ENSBTAT00000030236", "map_id": "ENSBTAT00000030236", "name": "SLC15A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048965", "map_id": "none", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane" }, { "id": "species_428592", "map_id": "none", "name": "Inhibitory amino acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_428632", "map_id": "none", "name": "Inhibitory amino acids", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20600", "compartment_display": "synaptic vesicle", "complex": "true" }, { "id": "species_10048962", "map_id": "G3N354", "name": "SLC32A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_201753", "compartment_display": "synaptic vesicle membrane", "complex": "false" }, { "id": "reaction_10048804", "map_id": "none", "name": "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_428027", "map_id": "none", "name": "L-Glu,L-Asp,D-Asp", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17364", "map_id": "CHEBI:17364", "name": "CHEBI:17364", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_427997", "map_id": "none", "name": "L-Glu,L-Asp,D-Asp", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10048491", "map_id": "none", "name": "SLC4A5,7,9 cotransport Na+ with 3HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048488", "map_id": "none", "name": "SLC4A5,7,9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BBH7", "map_id": "E1BBH7", "name": "SLC4A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006425", "map_id": "ENSBTAT00000006425", "name": "SLC4A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIN2", "map_id": "E1BIN2", "name": "SLC4A9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029024", "map_id": "ENSBTAT00000029024", "name": "SLC4A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048478", "map_id": "none", "name": "SLC4A1,2,3 exchanges HCO3- for Cl-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10048475", "map_id": "none", "name": "SLC4A1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BKK3", "map_id": "E1BKK3", "name": "SLC4A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019936", "map_id": "ENSBTAT00000019936", "name": "SLC4A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M051", "map_id": "A0A3Q1M051", "name": "SLC4A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071207", "map_id": "ENSBTAT00000071207", "name": "SLC4A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049053", "map_id": "none", "name": "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049050", "map_id": "A0A3Q1MNS2", "name": "SLC2A10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000066412", "map_id": "ENSBTAT00000066412", "name": "SLC2A10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089038", "map_id": "none", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089035", "map_id": "none", "name": "GLUT4 / SLC2A4 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q27994", "map_id": "Q27994", "name": "SLC2A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012109", "map_id": "ENSBTAT00000012109", "name": "SLC2A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089024", "map_id": "none", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089021", "map_id": "none", "name": "GLUT14 / SLC2A14 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MA30", "map_id": "A0A3Q1MA30", "name": "SLC2A14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042945", "map_id": "ENSBTAT00000042945", "name": "SLC2A14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085907", "map_id": "none", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085904", "map_id": "E1BMB9", "name": "SLC45A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000010116", "map_id": "ENSBTAT00000010116", "name": "SLC45A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10089029", "map_id": "none", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10089026", "map_id": "none", "name": "GLUT3 / SLC2A3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049046", "map_id": "none", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429078", "map_id": "none", "name": "Fru,Glc,urate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_429148", "map_id": "none", "name": "Fru,Glc,urate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10049043", "map_id": "A0A3Q1MQD9", "name": "SLC2A9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000079223", "map_id": "ENSBTAT00000079223", "name": "SLC2A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037913", "map_id": "none", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037857", "map_id": "none", "name": "factor X", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10037859", "map_id": "A0A452DIP8", "name": "F10", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10037807", "map_id": "none", "name": "factor Xa", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10037910", "map_id": "none", "name": "TF:F7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P30931", "map_id": "P30931", "name": "F3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009341", "map_id": "ENSBTAT00000009341", "name": "F3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22457", "map_id": "P22457", "name": "F7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037899", "map_id": "none", "name": "sequestered tissue factor -> tissue factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037897", "map_id": "P30931", "name": "F3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10037864", "map_id": "P30931", "name": "F3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10037915", "map_id": "none", "name": "tissue factor (TF) + factor VII (F7) -> TF:F7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037903", "map_id": "none", "name": "10xCbxE-F7(61-466):Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10037887", "map_id": "none", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037884", "map_id": "none", "name": "TF:F7a", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037937", "map_id": "none", "name": "TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037931", "map_id": "A0A3Q1NLA0", "name": "TFPI", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000085417", "map_id": "ENSBTAT00000085417", "name": "TFPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037935", "map_id": "none", "name": "TFPI:TF:F7a:factor Xa", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NLA0", "map_id": "A0A3Q1NLA0", "name": "TFPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037906", "map_id": "none", "name": "factor VII -> factor VIIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037893", "map_id": "none", "name": "factor VIIa", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10037895", "map_id": "none", "name": "tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10048635", "map_id": "none", "name": "Cation influx mediated by TRPC3/6/7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_426219", "map_id": "none", "name": "Cations", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_426221", "map_id": "none", "name": "Cations", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10037607", "map_id": "none", "name": "P2X1-mediated entry of Ca++ from plasma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037604", "map_id": "none", "name": "P2X purinoreceptors:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q5E9U1", "map_id": "Q5E9U1", "name": "P2RX4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014321", "map_id": "ENSBTAT00000014321", "name": "P2RX4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUF3", "map_id": "F1MUF3", "name": "P2RX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020298", "map_id": "ENSBTAT00000020298", "name": "P2RX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B742", "map_id": "E1B742", "name": "P2RX6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025626", "map_id": "ENSBTAT00000025626", "name": "P2RX6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044680", "map_id": "none", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044676", "map_id": "none", "name": "HMGB1/HMGB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40673", "map_id": "P40673", "name": "HMGB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020096", "map_id": "ENSBTAT00000020096", "name": "HMGB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29428", "map_id": "none", "name": "DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044678", "map_id": "none", "name": "HMGB1/HMGB2- bound chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044142", "map_id": "none", "name": "Translocation of DFF to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10044132", "map_id": "none", "name": "DFF:associated with the importin-alpha:importin-beta complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC37", "map_id": "Q0VC37", "name": "DFFA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017999", "map_id": "ENSBTAT00000017999", "name": "DFFA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N2E0", "map_id": "F1N2E0", "name": "DFFB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026657", "map_id": "ENSBTAT00000026657", "name": "DFFB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044140", "map_id": "none", "name": "DFF:associated with the importin-alpha:importin-beta complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044144", "map_id": "none", "name": "Cleaved fragments of DFF45 dissociate from DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044108", "map_id": "none", "name": "caspase-3-cleaved DFFA (117,224):DFFB complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10044098", "map_id": "Q0VC37", "name": "DFFA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044094", "map_id": "F1N2E0", "name": "DFFB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044106", "map_id": "Q0VC37", "name": "DFFA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044104", "map_id": "Q0VC37", "name": "DFFA", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10044146", "map_id": "none", "name": "Association of DFF40 with DFF45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044118", "map_id": "F1N2E0", "name": "DFFB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044120", "map_id": "Q0VC37", "name": "DFFA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044122", "map_id": "none", "name": "DFFA:DFFB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10044116", "map_id": "none", "name": "Homodimerization of DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044114", "map_id": "none", "name": "DFF40 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10066489", "map_id": "none", "name": "Phosphorylated BORA binds SCF-beta-TrCp1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066480", "map_id": "F1N3C9", "name": "phospho-BORA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026496", "map_id": "ENSBTAT00000026496", "name": "phospho-BORA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066482", "map_id": "none", "name": "p-S252,S497,T501-BORA:SCF-beta-TrCp1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N3C9", "map_id": "F1N3C9", "name": "phospho-BORA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065938", "map_id": "none", "name": "Phosphorylated OPTN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065934", "map_id": "Q3ZC32", "name": "phospho-OPTN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000021808", "map_id": "ENSBTAT00000021808", "name": "phospho-OPTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065936", "map_id": "Q3ZC32", "name": "phospho-OPTN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10066487", "map_id": "none", "name": "SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066484", "map_id": "none", "name": "Ub-p-S252,S497,T501-BORA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084216", "map_id": "none", "name": "Formation of the SCF-FBXL7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054914", "map_id": "F1N019", "name": "FBXL7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039822", "map_id": "F1MYD0", "name": "CUL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043871", "map_id": "A0A3Q1LNF8", "name": "LOC780968", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039818", "map_id": "Q3ZCF3", "name": "SKP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084098", "map_id": "none", "name": "SKP1:CUL1:RBX1:FBXL7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084206", "map_id": "none", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084100", "map_id": "none", "name": "SCF-FBXL7:AURKA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10084203", "map_id": "none", "name": "SCF-FBXL7:PolyUb-AURKA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10084102", "map_id": "none", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10084214", "map_id": "none", "name": "SCF-FBXL18 ubiquitinates FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084209", "map_id": "F1N019", "name": "FBXL7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084211", "map_id": "none", "name": "SKP1:CUL1:RBX1:FBXL18", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10039612", "map_id": "none", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10039608", "map_id": "A0A3Q1MCU3", "name": "CDC25B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000075264", "map_id": "ENSBTAT00000075264", "name": "CDC25B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10039610", "map_id": "A0A3Q1MCU3", "name": "CDC25B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039614", "map_id": "none", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "reaction_10084043", "map_id": "none", "name": "GTSE1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084039", "map_id": "F6Q0H8", "name": "phospho-GTSE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009339", "map_id": "ENSBTAT00000009339", "name": "GTSE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084041", "map_id": "F6Q0H8", "name": "phospho-GTSE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10084028", "map_id": "none", "name": "GTSE1 binds microtubule lattice in interphase cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084024", "map_id": "F6Q0H8", "name": "GTSE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10084026", "map_id": "none", "name": "GTSE1:microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F6Q0H8", "map_id": "F6Q0H8", "name": "GTSE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084047", "map_id": "none", "name": "GTSE1 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084045", "map_id": "none", "name": "p-S435-GTSE1:PolyUb-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10084051", "map_id": "none", "name": "GTSE1 promotes translocation of TP53 to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084049", "map_id": "none", "name": "p-S435-GTSE1:PolyUb-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10087635", "map_id": "none", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10039037", "map_id": "none", "name": "F1Fo ATP synthase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "A0A452DII8", "map_id": "A0A452DII8", "name": "ATP5F1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017710", "map_id": "ENSBTAT00000017710", "name": "ATP5F1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05631", "map_id": "P05631", "name": "ATP5F1C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081996", "map_id": "ENSBTAT00000081996", "name": "ATP5F1C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05630", "map_id": "P05630", "name": "ATP5F1D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000721", "map_id": "ENSBTAT00000000721", "name": "ATP5F1D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05632", "map_id": "P05632", "name": "ATP5F1E", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085877", "map_id": "ENSBTAT00000085877", "name": "ATP5F1E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P03929", "map_id": "P03929", "name": "MT-ATP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060553", "map_id": "ENSBTAT00000060553", "name": "MT-ATP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MP66", "map_id": "A0A3Q1MP66", "name": "ATP5F1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072644", "map_id": "ENSBTAT00000072644", "name": "ATP5F1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00847", "map_id": "P00847", "name": "MT-ATP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060539", "map_id": "ENSBTAT00000060539", "name": "MT-ATP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC75", "map_id": "Q3ZC75", "name": "ATP5MC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003832", "map_id": "ENSBTAT00000003832", "name": "ATP5MC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P13620", "map_id": "P13620", "name": "ATP5PD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074726", "map_id": "ENSBTAT00000074726", "name": "ATP5PD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7G3", "map_id": "A0A3Q1M7G3", "name": "ATP5J2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077018", "map_id": "ENSBTAT00000077018", "name": "ATP5J2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCR1", "map_id": "A0A3Q1MCR1", "name": "ATP5J2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N4G2", "map_id": "A0A3Q1N4G2", "name": "ATP5J2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q00361", "map_id": "Q00361", "name": "ATP5ME", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023255", "map_id": "ENSBTAT00000023255", "name": "ATP5ME", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A0N4STN0", "map_id": "A0A0N4STN0", "name": "ATP5MG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009643", "map_id": "ENSBTAT00000009643", "name": "ATP5MG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI29", "map_id": "A0A452DI29", "name": "ATP5MC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007538", "map_id": "ENSBTAT00000007538", "name": "ATP5MC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32876", "map_id": "P32876", "name": "ATP5MC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024402", "map_id": "ENSBTAT00000024402", "name": "ATP5MC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P13621", "map_id": "P13621", "name": "ATP5PO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024326", "map_id": "ENSBTAT00000024326", "name": "ATP5PO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087633", "map_id": "none", "name": "F1Fo ATP synthase dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10052963", "map_id": "none", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10052929", "map_id": "E1BEK9", "name": "UPF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000027868", "map_id": "ENSBTAT00000027868", "name": "phospho-UPF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052959", "map_id": "none", "name": "Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MH45", "map_id": "A0A3Q1MH45", "name": "GSPT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017703", "map_id": "ENSBTAT00000017703", "name": "GSPT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6Q087", "map_id": "F6Q087", "name": "GSPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004656", "map_id": "ENSBTAT00000004656", "name": "GSPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10052961", "map_id": "none", "name": "UPF1:eRF3 Complex on Translated mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BEK9", "map_id": "E1BEK9", "name": "phospho-UPF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083789", "map_id": "none", "name": "SALMs 1-3 bind to PSD-95 family members", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083783", "map_id": "none", "name": "PSD-95 family", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10083785", "map_id": "none", "name": "SALM1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MZS2", "map_id": "G3MZS2", "name": "LRFN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063750", "map_id": "ENSBTAT00000063750", "name": "LRFN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDP0", "map_id": "E1BDP0", "name": "LRFN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023907", "map_id": "ENSBTAT00000023907", "name": "LRFN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJL8", "map_id": "F1MJL8", "name": "LRFN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000053062", "map_id": "ENSBTAT00000053062", "name": "LRFN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083787", "map_id": "none", "name": "SALMs 1-3:PSD-95 family", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10083793", "map_id": "none", "name": "SALMs1-3 bind each other in cis interactions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083791", "map_id": "none", "name": "SALM1,2,3 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10084356", "map_id": "none", "name": "SALM3 binds LAR-RPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10083779", "map_id": "F1MJL8", "name": "LRFN4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084354", "map_id": "none", "name": "SALM3:LAR-RPTPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10087862", "map_id": "none", "name": "RUNX3 binds TEADs and YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087858", "map_id": "none", "name": "YAP1:TEAD1,TEAD4,(TEAD2,TEAD3)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N1G2", "map_id": "A0A3Q1N1G2", "name": "TEAD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067627", "map_id": "ENSBTAT00000067627", "name": "TEAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M163", "map_id": "A0A3Q1M163", "name": "TEAD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074335", "map_id": "ENSBTAT00000074335", "name": "TEAD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10087860", "map_id": "none", "name": "RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087997", "map_id": "none", "name": "CCND1 binds RUNX3 and displaces EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087908", "map_id": "none", "name": "Ac-K94,K171-RUNX3:CBFB:EP300:BRD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q32S26", "map_id": "Q32S26", "name": "BRD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014704", "map_id": "ENSBTAT00000014704", "name": "BRD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056568", "map_id": "A0A452DIV3", "name": "CCND1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10087995", "map_id": "none", "name": "Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087900", "map_id": "none", "name": "EP300 acetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087887", "map_id": "none", "name": "RUNX3:CBFB:EP300", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10087897", "map_id": "none", "name": "Ac-K94,K171-RUNX3:CBFB:EP300", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087889", "map_id": "none", "name": "RUNX3 binds EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084945", "map_id": "none", "name": "RUNX3:CBFB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087910", "map_id": "none", "name": "Acetylated RUNX3 binds to BRD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10087906", "map_id": "none", "name": "BRD2 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10088006", "map_id": "none", "name": "HDAC4 deacetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088001", "map_id": "none", "name": "Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1:HDAC4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10088003", "map_id": "none", "name": "RUNX3:CBFB:CCND1:HDAC4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427486", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10088012", "map_id": "none", "name": "RUNX3 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088010", "map_id": "none", "name": "RUNX3:TP53 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086231", "map_id": "none", "name": "RUNX3 binds ZFHX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086227", "map_id": "E1BPV9", "name": "ZFHX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000019489", "map_id": "ENSBTAT00000019489", "name": "ZFHX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086229", "map_id": "none", "name": "RUNX3:ZFHX3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BPV9", "map_id": "E1BPV9", "name": "ZFHX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086587", "map_id": "none", "name": "SRC phosphorylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10086579", "map_id": "none", "name": "MyrG-p-Y419-SRC:RUNX3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10086584", "map_id": "A0A3Q1MYL2", "name": "phospho-RUNX3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10088490", "map_id": "none", "name": "SMURFs ubiquitinate RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088485", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10088487", "map_id": "F1MLS5", "name": "SMURF1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10086589", "map_id": "none", "name": "RUNX3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10086577", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10084947", "map_id": "none", "name": "CBFB binds RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084939", "map_id": "E1B9S8", "name": "CBFB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10088482", "map_id": "none", "name": "Polyubiquitinated RUNX3 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088478", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10088480", "map_id": "A0A3Q1MYL2", "name": "RUNX3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10086581", "map_id": "none", "name": "RUNX3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040059", "map_id": "none", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10040054", "map_id": "none", "name": "Rad17-RFC complex bound to DNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LY33", "map_id": "A0A3Q1LY33", "name": "RFC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085991", "map_id": "ENSBTAT00000085991", "name": "RFC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1J3", "map_id": "A0A3Q1M1J3", "name": "RFC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071469", "map_id": "ENSBTAT00000071469", "name": "RFC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBV1", "map_id": "Q2TBV1", "name": "RFC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014278", "map_id": "ENSBTAT00000014278", "name": "RFC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNK6", "map_id": "A6QNK6", "name": "RAD17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002682", "map_id": "ENSBTAT00000002682", "name": "RAD17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KI86", "map_id": "Q2KI86", "name": "RPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008174", "map_id": "ENSBTAT00000008174", "name": "RPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZ11", "map_id": "Q3SZ11", "name": "RPA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017525", "map_id": "ENSBTAT00000017525", "name": "RPA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040050", "map_id": "none", "name": "RAD9:HUS1:RAD1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MFW1", "map_id": "F1MFW1", "name": "RAD9B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024392", "map_id": "ENSBTAT00000024392", "name": "RAD9B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG06", "map_id": "E1BG06", "name": "HUS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017599", "map_id": "ENSBTAT00000017599", "name": "HUS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB72", "map_id": "E1BB72", "name": "RAD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025568", "map_id": "ENSBTAT00000025568", "name": "RAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040056", "map_id": "none", "name": "Rad9-Hus1-Rad1 bound to DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10040955", "map_id": "none", "name": "Phosphorylation of Cx43 by c-src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040945", "map_id": "none", "name": "Cx43:ZO-1:c-src gap junction", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10040952", "map_id": "none", "name": "phospho-Y265 Cx43:ZO-1 gap junction", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040961", "map_id": "none", "name": "c-src associates with Cx43 in gap junctions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040959", "map_id": "none", "name": "Cx43 :ZO-1 gap junction", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040967", "map_id": "none", "name": "Closure of gap junction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10040965", "map_id": "none", "name": "c-src-associated Cx43 junctional channel", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10085313", "map_id": "none", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060424", "map_id": "A0A3Q1MBL1", "name": "PIP5K1C", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083179", "map_id": "none", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10083175", "map_id": "none", "name": "TGN Golgin dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BFF9", "map_id": "E1BFF9", "name": "GOLGA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020327", "map_id": "ENSBTAT00000020327", "name": "GOLGA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJZ4", "map_id": "E1BJZ4", "name": "GCC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004036", "map_id": "ENSBTAT00000004036", "name": "GCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPM7", "map_id": "A0A3Q1MPM7", "name": "GOLGA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082501", "map_id": "ENSBTAT00000082501", "name": "GOLGA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUW6", "map_id": "F1MUW6", "name": "TMF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046850", "map_id": "ENSBTAT00000046850", "name": "TMF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083141", "map_id": "none", "name": "AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q1RMQ3", "map_id": "Q1RMQ3", "name": "SYS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006825", "map_id": "ENSBTAT00000006825", "name": "SYS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q32LJ2", "map_id": "Q32LJ2", "name": "ARFRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009858", "map_id": "ENSBTAT00000009858", "name": "ARFRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2YDM1", "map_id": "Q2YDM1", "name": "ARL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015767", "map_id": "ENSBTAT00000015767", "name": "ARL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083177", "map_id": "none", "name": "AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10083149", "map_id": "none", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10083119", "map_id": "Q1RMQ3", "name": "SYS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10083147", "map_id": "none", "name": "AcM-ARFRP1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10083128", "map_id": "none", "name": "AcM-ARFRP1:GTP:SYS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10083340", "map_id": "none", "name": "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_432051", "compartment_display": "transport vesicle" }, { "id": "species_10083331", "map_id": "none", "name": "RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "Q5EA50", "map_id": "Q5EA50", "name": "phospho-RABEPK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074576", "map_id": "ENSBTAT00000074576", "name": "phospho-RABEPK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083333", "map_id": "none", "name": "RAB9:GTP:p-RABEPK:VAMP3:late endosome-to-TGN cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "species_10083337", "map_id": "Q3SX32", "name": "PLIN3", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083342", "map_id": "none", "name": "RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10083323", "map_id": "none", "name": "RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "reaction_10083187", "map_id": "none", "name": "ARL1:GTP binds SCOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083183", "map_id": "A0A3Q1M9K7", "name": "SCOC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000065986", "map_id": "ENSBTAT00000065986", "name": "SCOC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083135", "map_id": "none", "name": "MyrG-ARL1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10083185", "map_id": "none", "name": "SCOC:MyrG-ARL1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M9K7", "map_id": "A0A3Q1M9K7", "name": "SCOC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083143", "map_id": "none", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "reaction_10083451", "map_id": "none", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10060581", "map_id": "none", "name": "ARF1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10083439", "map_id": "none", "name": "CYTH1,2,3,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LM77", "map_id": "A0A3Q1LM77", "name": "CYTH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084376", "map_id": "ENSBTAT00000084376", "name": "CYTH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M9S8", "map_id": "A0A3Q1M9S8", "name": "CYTH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086938", "map_id": "ENSBTAT00000086938", "name": "CYTH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LS50", "map_id": "A0A3Q1LS50", "name": "CYTH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086695", "map_id": "ENSBTAT00000086695", "name": "CYTH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083449", "map_id": "none", "name": "ARF1:GTP:CYTH1,2,3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10083425", "map_id": "none", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10083421", "map_id": "none", "name": "TRIP11:cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "A0A3Q1MQ84", "map_id": "A0A3Q1MQ84", "name": "TRIP11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084706", "map_id": "ENSBTAT00000084706", "name": "TRIP11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083423", "map_id": "none", "name": "ARF1:GTP:TRIP11:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10083056", "map_id": "none", "name": "The COG tethering complex interacts with numerous SNAREs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10082114", "map_id": "none", "name": "COG complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BK29", "map_id": "E1BK29", "name": "COG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007999", "map_id": "ENSBTAT00000007999", "name": "COG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MQ89", "map_id": "F1MQ89", "name": "COG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027073", "map_id": "ENSBTAT00000027073", "name": "COG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DKB6", "map_id": "A0A452DKB6", "name": "COG7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045677", "map_id": "ENSBTAT00000045677", "name": "COG7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGA6", "map_id": "E1BGA6", "name": "COG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023803", "map_id": "ENSBTAT00000023803", "name": "COG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5R4", "map_id": "F1N5R4", "name": "COG8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002179", "map_id": "ENSBTAT00000002179", "name": "COG8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3MHG0", "map_id": "Q3MHG0", "name": "COG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017269", "map_id": "ENSBTAT00000017269", "name": "COG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083052", "map_id": "none", "name": "other COG interacting snares", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "F1MDA6", "map_id": "F1MDA6", "name": "VPS45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027499", "map_id": "ENSBTAT00000027499", "name": "VPS45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIQ3", "map_id": "E1BIQ3", "name": "STX16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005055", "map_id": "ENSBTAT00000005055", "name": "STX16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTE3", "map_id": "A0A3Q1LTE3", "name": "VTI1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075149", "map_id": "ENSBTAT00000075149", "name": "VTI1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083054", "map_id": "none", "name": "COG complex:Golgi snares", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10083458", "map_id": "none", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10083455", "map_id": "none", "name": "ARF1:GDP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10083767", "map_id": "none", "name": "The COG complex binds RABs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10083763", "map_id": "none", "name": "other COG-interacting RABs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "E1BJ06", "map_id": "E1BJ06", "name": "RAB36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017437", "map_id": "ENSBTAT00000017437", "name": "RAB36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M591", "map_id": "A0A3Q1M591", "name": "RAB43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073539", "map_id": "ENSBTAT00000073539", "name": "RAB43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10083765", "map_id": "none", "name": "COG complex:RABs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10065827", "map_id": "none", "name": "SPAM1 Binds Hyaluronic Acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065823", "map_id": "F1MZM9", "name": "LOC509761", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000045309", "map_id": "ENSBTAT00000045309", "name": "LOC509761", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1297302", "map_id": "CHEBI:16336", "name": "HUA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10065825", "map_id": "none", "name": "SPAM1:Hyaluronic acid", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MZM9", "map_id": "F1MZM9", "name": "LOC509761", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10047292", "map_id": "none", "name": "SIRPA binds SFTPA oligomer, SFTPD oligomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10047270", "map_id": "none", "name": "Homologues of SIRPA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047288", "map_id": "none", "name": "SFTPA oligomer, SFTPD oligomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10047290", "map_id": "none", "name": "SIRPA:SFTPA oligomer, SFTPD oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10060207", "map_id": "none", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174369", "map_id": "CHEBI:17230", "name": "HCYS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1614518", "map_id": "CHEBI:17482", "name": "L-Cystathionine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060204", "map_id": "none", "name": "PXLP-CBS tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MEW4", "map_id": "F1MEW4", "name": "CBS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087445", "map_id": "ENSBTAT00000087445", "name": "CBS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060231", "map_id": "none", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_936714", "map_id": "CHEBI:30831", "name": "2OBUTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060225", "map_id": "none", "name": "PXLP-K212-CTH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M2L1", "map_id": "A0A3Q1M2L1", "name": "PXLP-K212-CTH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005788", "map_id": "ENSBTAT00000005788", "name": "PXLP-K212-CTH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060275", "map_id": "none", "name": "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614585", "map_id": "CHEBI:17724", "name": "DMGLY", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060272", "map_id": "none", "name": "BHMT:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DHV7", "map_id": "A0A452DHV7", "name": "BHMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002916", "map_id": "ENSBTAT00000002916", "name": "BHMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057032", "map_id": "none", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353106", "map_id": "CHEBI:17509", "name": "MTAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237165", "map_id": "CHEBI:58533", "name": "MTRIBP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_83951", "map_id": "CHEBI:16708", "name": "Ade", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057029", "map_id": "none", "name": "MTAP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3MHF7", "map_id": "Q3MHF7", "name": "MTAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048509", "map_id": "ENSBTAT00000048509", "name": "MTAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057023", "map_id": "none", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237176", "map_id": "CHEBI:58828", "name": "2,3-DMPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237155", "map_id": "CHEBI:58795", "name": "Acireductone", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057020", "map_id": "none", "name": "E1:Mg++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VD27", "map_id": "Q0VD27", "name": "ENOPH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019702", "map_id": "ENSBTAT00000019702", "name": "ENOPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057684", "map_id": "none", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237107", "map_id": "CHEBI:58548", "name": "MTRIBUP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10057011", "map_id": "A0A452DHW8", "name": "MRI1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000003273", "map_id": "ENSBTAT00000003273", "name": "MRI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090681", "map_id": "none", "name": "CysS248-MPST:TXN2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10090677", "map_id": "none", "name": "CysS248-MPST:TXN2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1M9D2", "map_id": "A0A3Q1M9D2", "name": "MPST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069079", "map_id": "ENSBTAT00000069079", "name": "MPST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q95108", "map_id": "Q95108", "name": "TXN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089847", "map_id": "A0A3Q1M9D2", "name": "MPST", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1655881", "map_id": "CHEBI:16136", "name": "H2S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10089850", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9012724", "map_id": "CHEBI:17137", "name": "HSO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9012592", "map_id": "CHEBI:16208", "name": "3MPYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1614595", "map_id": "CHEBI:16094", "name": "S2O3(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10090013", "map_id": "none", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013199", "map_id": "CHEBI:18407", "name": "HCN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013191", "map_id": "CHEBI:29200", "name": "HSCN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10060252", "map_id": "none", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614532", "map_id": "CHEBI:16136", "name": "H2S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060255", "map_id": "none", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090015", "map_id": "none", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013543", "map_id": "none", "name": "sulfanegen", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10090679", "map_id": "none", "name": "TXN2 binds CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10090669", "map_id": "A0A3Q1M9D2", "name": "MPST", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10060361", "map_id": "none", "name": "Thiosulfate can transfer its sulfur atom to glutathione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_1614538", "map_id": "CHEBI:17359", "name": "sulfite(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10060358", "map_id": "F1MW03", "name": "TSTD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000023735", "map_id": "ENSBTAT00000023735", "name": "TSTD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060216", "map_id": "none", "name": "Sulfite is oxidized to sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10060213", "map_id": "none", "name": "holo-SUOX", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q3MHX0", "map_id": "Q3MHX0", "name": "SUOX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008101", "map_id": "ENSBTAT00000008101", "name": "SUOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060250", "map_id": "none", "name": "Persulfide sulfur is dioxygenated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10060239", "map_id": "F1MKF8", "name": "SQOR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000013690", "map_id": "ENSBTAT00000013690", "name": "SQOR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060241", "map_id": "F1MKF8", "name": "SQOR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10060247", "map_id": "none", "name": "ETHE1:2Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q3T094", "map_id": "Q3T094", "name": "ETHE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005747", "map_id": "ENSBTAT00000005747", "name": "ETHE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060264", "map_id": "none", "name": "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614519", "map_id": "CHEBI:16345", "name": "3-Sulfinoalanine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060261", "map_id": "none", "name": "CDO1:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MCZ5", "map_id": "A0A3Q1MCZ5", "name": "CDO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079843", "map_id": "ENSBTAT00000079843", "name": "CDO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060234", "map_id": "none", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614582", "map_id": "CHEBI:21347", "name": "L-Lanthionine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090671", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10083204", "map_id": "none", "name": "ADO oxidises 2AET to HTAU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6814151", "map_id": "CHEBI:17141", "name": "2AET", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1655445", "map_id": "CHEBI:16668", "name": "HTAU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083201", "map_id": "none", "name": "ADO:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3MZK0", "map_id": "G3MZK0", "name": "ADO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064438", "map_id": "ENSBTAT00000064438", "name": "ADO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060228", "map_id": "none", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614594", "map_id": "CHEBI:62856", "name": "HLAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10089959", "map_id": "none", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013207", "map_id": "CHEBI:17359", "name": "SO3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10089956", "map_id": "A0A452DJ91", "name": "TST", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000043317", "map_id": "ENSBTAT00000043317", "name": "TST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077124", "map_id": "none", "name": "BHMT2 tetramer transfers CH3 group from SMM to LHCYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_4789070", "map_id": "CHEBI:17728", "name": "SMM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077121", "map_id": "none", "name": "BHMT2:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N4C6", "map_id": "F1N4C6", "name": "BHMT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048928", "map_id": "ENSBTAT00000048928", "name": "BHMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078575", "map_id": "none", "name": "SARDH:FAD oxidatively demethylates SARC to Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6797917", "map_id": "CHEBI:15611", "name": "SARC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6797920", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078572", "map_id": "none", "name": "SARDH:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MR10", "map_id": "A0A3Q1MR10", "name": "SARDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075705", "map_id": "ENSBTAT00000075705", "name": "SARDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078582", "map_id": "none", "name": "CHDH oxidises Cho to BETALD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6798162", "map_id": "CHEBI:15354", "name": "Cho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6798194", "map_id": "CHEBI:15710", "name": "BETALD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10078579", "map_id": "E1BES2", "name": "CHDH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000013227", "map_id": "ENSBTAT00000013227", "name": "CHDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044844", "map_id": "none", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353113", "map_id": "CHEBI:15625", "name": "dc-AdoMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044841", "map_id": "E1BM12", "name": "SRM", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000006978", "map_id": "ENSBTAT00000006978", "name": "SRM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044851", "map_id": "none", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044848", "map_id": "A0A3Q1LTI7", "name": "AMD1(1-67)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000054971", "map_id": "ENSBTAT00000054971", "name": "AMD1(1-67)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033778", "map_id": "none", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10033788", "map_id": "none", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_508182", "map_id": "none", "name": "Leu, Ile, Val", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_508187", "map_id": "none", "name": "KIC,KMVA,KIV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28654", "map_id": "CHEBI:28654", "name": "CHEBI:28654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17865", "map_id": "CHEBI:17865", "name": "CHEBI:17865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16530", "map_id": "CHEBI:16530", "name": "CHEBI:16530", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10033785", "map_id": "none", "name": "BCAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1ML78", "map_id": "A0A3Q1ML78", "name": "BCAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086973", "map_id": "ENSBTAT00000086973", "name": "BCAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033806", "map_id": "none", "name": "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70772", "map_id": "CHEBI:15488", "name": "bMC-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70784", "map_id": "CHEBI:15467", "name": "bHMG-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033803", "map_id": "none", "name": "AUH hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1M9N4", "map_id": "A0A3Q1M9N4", "name": "AUH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068139", "map_id": "ENSBTAT00000068139", "name": "AUH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051185", "map_id": "none", "name": "alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70836", "map_id": "CHEBI:15476", "name": "2MACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70829", "map_id": "CHEBI:15449", "name": "aMbHBUT-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033812", "map_id": "none", "name": "HSD17B10 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O02691", "map_id": "O02691", "name": "HSD17B10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023642", "map_id": "ENSBTAT00000023642", "name": "HSD17B10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033824", "map_id": "none", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10033821", "map_id": "none", "name": "ACAT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q29RZ0", "map_id": "Q29RZ0", "name": "ACAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017122", "map_id": "ENSBTAT00000017122", "name": "ACAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033797", "map_id": "none", "name": "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70715", "map_id": "CHEBI:15487", "name": "ISV-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70744", "map_id": "CHEBI:15486", "name": "bMC-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033794", "map_id": "none", "name": "IVD tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A452DI40", "map_id": "A0A452DI40", "name": "IVD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005782", "map_id": "ENSBTAT00000005782", "name": "IVD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052027", "map_id": "none", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_33179", "map_id": "CHEBI:18377", "name": "NFK", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10052024", "map_id": "none", "name": "IDO2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BPE1", "map_id": "E1BPE1", "name": "IDO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007525", "map_id": "ENSBTAT00000007525", "name": "IDO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052043", "map_id": "none", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29970", "map_id": "CHEBI:16946", "name": "L-KYN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_893615", "map_id": "CHEBI:17442", "name": "AP-DOBu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8939576", "map_id": "none", "name": "I3LACT, I3PROPA", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:55528", "map_id": "CHEBI:55528", "name": "CHEBI:55528", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:43580", "map_id": "CHEBI:43580", "name": "CHEBI:43580", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033979", "map_id": "none", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_34351", "map_id": "CHEBI:17380", "name": "3HKYN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30487", "map_id": "CHEBI:15793", "name": "3HAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033976", "map_id": "none", "name": "KYNU dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MB81", "map_id": "A0A3Q1MB81", "name": "KYNU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069075", "map_id": "ENSBTAT00000069075", "name": "KYNU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052030", "map_id": "none", "name": "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_893607", "map_id": "CHEBI:16946", "name": "L-KYN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_893617", "map_id": "CHEBI:17442", "name": "APDBA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10033856", "map_id": "none", "name": "AADAT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LKR3", "map_id": "A0A3Q1LKR3", "name": "AADAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085694", "map_id": "ENSBTAT00000085694", "name": "AADAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033969", "map_id": "none", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10033966", "map_id": "A0A3Q1M294", "name": "KMO", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000073847", "map_id": "ENSBTAT00000073847", "name": "KMO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085381", "map_id": "none", "name": "SLC36A4 transports L-Trp from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10033988", "map_id": "none", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_36027", "map_id": "CHEBI:29044", "name": "ACS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10033985", "map_id": "none", "name": "HAAO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DIN3", "map_id": "A0A452DIN3", "name": "HAAO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006132", "map_id": "ENSBTAT00000006132", "name": "HAAO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041894", "map_id": "none", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041891", "map_id": "none", "name": "IDO1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LFW8", "map_id": "A0A3Q1LFW8", "name": "IDO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070085", "map_id": "ENSBTAT00000070085", "name": "IDO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090155", "map_id": "none", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9014643", "map_id": "CHEBI:58020", "name": "2AA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090152", "map_id": "none", "name": "PXLP-K48-SDSL dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A5PKH5", "map_id": "A5PKH5", "name": "SDSL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011776", "map_id": "ENSBTAT00000011776", "name": "SDSL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090162", "map_id": "none", "name": "HRSP12 deaminates 2AA to 2OBUTA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090159", "map_id": "Q3T114", "name": "RIDA", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000016718", "map_id": "ENSBTAT00000016718", "name": "RIDA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065455", "map_id": "none", "name": "Sec is reduced to H2Se by PXLP-K259-SCLY dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5359016", "map_id": "none", "name": "reduced acceptor", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357697", "map_id": "CHEBI:16633", "name": "Sec", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357660", "map_id": "CHEBI:16503", "name": "H2Se", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5359011", "map_id": "none", "name": "acceptor", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065452", "map_id": "none", "name": "PXLP-K259-SCLY dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A2VDS1", "map_id": "A2VDS1", "name": "SCLY", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013719", "map_id": "ENSBTAT00000013719", "name": "SCLY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054601", "map_id": "none", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_936706", "map_id": "CHEBI:15811", "name": "O-P-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10054598", "map_id": "none", "name": "PSPH:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2KHU0", "map_id": "Q2KHU0", "name": "PSPH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017392", "map_id": "ENSBTAT00000017392", "name": "PSPH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10054620", "map_id": "none", "name": "PHGHD tetramer dehydrogenates 3PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_977329", "map_id": "CHEBI:30933", "name": "3POPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10054617", "map_id": "none", "name": "PHGHD tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A140T866", "map_id": "A0A140T866", "name": "PHGDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008907", "map_id": "ENSBTAT00000008907", "name": "PHGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090172", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_376186", "map_id": "CHEBI:16523", "name": "D-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090169", "map_id": "none", "name": "PXLP-K56-SRR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0JNI4", "map_id": "A0JNI4", "name": "SRR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005532", "map_id": "ENSBTAT00000005532", "name": "SRR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090175", "map_id": "none", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10054611", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10054608", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3S5ZPF7", "map_id": "A0A3S5ZPF7", "name": "PSAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018554", "map_id": "ENSBTAT00000018554", "name": "PSAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086371", "map_id": "none", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932979", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10086368", "map_id": "none", "name": "SERINC3,5,(1,2,4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4FUZ5", "map_id": "A4FUZ5", "name": "SERINC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002833", "map_id": "ENSBTAT00000002833", "name": "SERINC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LF32", "map_id": "A0A3Q1LF32", "name": "SERINC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072137", "map_id": "ENSBTAT00000072137", "name": "SERINC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090647", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10051165", "map_id": "none", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_31339", "map_id": "CHEBI:17232", "name": "L-Glu5S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10051162", "map_id": "none", "name": "P5CS dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q2KJH7", "map_id": "Q2KJH7", "name": "ALDH18A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015703", "map_id": "ENSBTAT00000015703", "name": "ALDH18A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077453", "map_id": "none", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35305", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077450", "map_id": "none", "name": "PYCRL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q58D08", "map_id": "Q58D08", "name": "PYCR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022364", "map_id": "ENSBTAT00000022364", "name": "PYCR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087455", "map_id": "none", "name": "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087452", "map_id": "none", "name": "RIMKLA, RIMKLB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VCE9", "map_id": "Q0VCE9", "name": "RIMKLB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004262", "map_id": "ENSBTAT00000004262", "name": "RIMKLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0M1", "map_id": "F1N0M1", "name": "RIMKLA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023262", "map_id": "ENSBTAT00000023262", "name": "RIMKLA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052046", "map_id": "none", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_893598", "map_id": "CHEBI:30882", "name": "2OGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10077444", "map_id": "none", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113590", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10077441", "map_id": "none", "name": "PYCR2 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q17QJ7", "map_id": "Q17QJ7", "name": "PYCR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000047", "map_id": "ENSBTAT00000000047", "name": "PYCR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077864", "map_id": "none", "name": "HYKK phosphorylates 5HLYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6788606", "map_id": "CHEBI:60175", "name": "5HLYS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10077861", "map_id": "A5PJU6", "name": "HYKK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000067508", "map_id": "ENSBTAT00000067508", "name": "HYKK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077435", "map_id": "none", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_5693325", "map_id": "CHEBI:30913", "name": "PPCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6783877", "map_id": "CHEBI:58769", "name": "P6C", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10077432", "map_id": "Q29RU9", "name": "PIPOX", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000010444", "map_id": "ENSBTAT00000010444", "name": "PIPOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10045036", "map_id": "none", "name": "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113577", "map_id": "CHEBI:15753", "name": "aKADA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_70951", "map_id": "CHEBI:15753", "name": "aKADA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10045033", "map_id": "A0A3Q1LPS4", "name": "SLC25A21", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000077809", "map_id": "ENSBTAT00000077809", "name": "SLC25A21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051198", "map_id": "none", "name": "alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_508531", "map_id": "CHEBI:17082", "name": "2AMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10076261", "map_id": "none", "name": "CRYM reduces P2C to PPCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_5693311", "map_id": "CHEBI:16187", "name": "P2C", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10076258", "map_id": "Q2KHX6", "name": "CRYM", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000012972", "map_id": "ENSBTAT00000012972", "name": "CRYM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10033997", "map_id": "none", "name": "arginine + glycine => ornithine + guanidoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_113545", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_113543", "map_id": "CHEBI:16344", "name": "GAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10033994", "map_id": "none", "name": "GATM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q2HJ74", "map_id": "Q2HJ74", "name": "GATM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007338", "map_id": "ENSBTAT00000007338", "name": "GATM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042847", "map_id": "none", "name": "creatine + ATP => phosphocreatine + ADP [CK octamer]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_29916", "map_id": "CHEBI:16919", "name": "CRET", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200351", "map_id": "CHEBI:17287", "name": "Pcr", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10042844", "map_id": "none", "name": "creatine kinase, ubiquitous, octamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q9TTK8", "map_id": "Q9TTK8", "name": "CKMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009871", "map_id": "ENSBTAT00000009871", "name": "CKMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034004", "map_id": "none", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30401", "map_id": "CHEBI:16344", "name": "GAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034001", "map_id": "Q2TBQ3", "name": "GAMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000005375", "map_id": "ENSBTAT00000005375", "name": "GAMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10042838", "map_id": "none", "name": "creatine + ATP => phosphocreatine + ADP [CKB,CKM]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10042835", "map_id": "none", "name": "creatine kinase BB dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q5EA61", "map_id": "Q5EA61", "name": "CKB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050490", "map_id": "ENSBTAT00000050490", "name": "CKB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066232", "map_id": "none", "name": "BESTs transport cytosolic HCO3- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066224", "map_id": "none", "name": "BESTs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A1A4I7", "map_id": "A1A4I7", "name": "BEST1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046067", "map_id": "ENSBTAT00000046067", "name": "BEST1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084767", "map_id": "none", "name": "ASICs bind STOML3, (STOM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065958", "map_id": "none", "name": "ASIC trimers:H+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MTH0", "map_id": "F1MTH0", "name": "ASIC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001283", "map_id": "ENSBTAT00000001283", "name": "ASIC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGK7", "map_id": "F1MGK7", "name": "ASIC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061078", "map_id": "ENSBTAT00000061078", "name": "ASIC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084763", "map_id": "none", "name": "STOML3, (STOM)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MCB3", "map_id": "F1MCB3", "name": "STOML3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024268", "map_id": "ENSBTAT00000024268", "name": "STOML3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084765", "map_id": "none", "name": "ASIC trimers:H+:STOML3,(STOM)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091583", "map_id": "none", "name": "ANO1 transports cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065970", "map_id": "A0A3Q1MCG6", "name": "ANO1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000067569", "map_id": "ENSBTAT00000067569", "name": "ANO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066206", "map_id": "none", "name": "TTYH2/3 transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066203", "map_id": "A0A3Q1M2Y5", "name": "TTYH3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000080053", "map_id": "ENSBTAT00000080053", "name": "TTYH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066270", "map_id": "none", "name": "SLC9B1/C2 exchange Na+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10066267", "map_id": "F1MFR7", "name": "SLC9B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000027774", "map_id": "ENSBTAT00000027774", "name": "SLC9B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066289", "map_id": "none", "name": "SLC9B2 exchanges Na+, Li+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_2889081", "map_id": "none", "name": "Na+/Li+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_8953505", "map_id": "CHEBI:49713", "name": "Li+", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_2889062", "map_id": "none", "name": "Na+/Li+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10066286", "map_id": "E1BFC4", "name": "SLC9B2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000085969", "map_id": "ENSBTAT00000085969", "name": "SLC9B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066227", "map_id": "none", "name": "BESTs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10066034", "map_id": "none", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2731008", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_74722", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10066031", "map_id": "none", "name": "CLCN4/5/6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "G3N3A9", "map_id": "G3N3A9", "name": "CLCN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064202", "map_id": "ENSBTAT00000064202", "name": "CLCN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BK15", "map_id": "E1BK15", "name": "CLCN6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027587", "map_id": "ENSBTAT00000027587", "name": "CLCN6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066004", "map_id": "none", "name": "TPCN1/2 transport lysosomal Ca2+ to cytosol ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1606834", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10066001", "map_id": "none", "name": "TPCN1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "A0A3Q1MQ38", "map_id": "A0A3Q1MQ38", "name": "TPCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082890", "map_id": "ENSBTAT00000082890", "name": "TPCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N2G9", "map_id": "A0A3Q1N2G9", "name": "TPCN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077727", "map_id": "ENSBTAT00000077727", "name": "TPCN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2730676", "map_id": "CHEBI:76072", "name": "NAADP", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10066199", "map_id": "none", "name": "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066196", "map_id": "none", "name": "CLCN1/2/KA/KB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BLQ0", "map_id": "E1BLQ0", "name": "CLCN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012099", "map_id": "ENSBTAT00000012099", "name": "CLCN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEP9", "map_id": "E1BEP9", "name": "BSND", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017615", "map_id": "ENSBTAT00000017615", "name": "BSND", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B792", "map_id": "E1B792", "name": "CLCNKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049019", "map_id": "ENSBTAT00000049019", "name": "CLCNKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091542", "map_id": "none", "name": "ASIC trimers bind H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10091540", "map_id": "none", "name": "ASIC trimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10066282", "map_id": "none", "name": "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2892454", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10066279", "map_id": "Q17QE9", "name": "SLC17A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000035648", "map_id": "ENSBTAT00000035648", "name": "SLC17A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065965", "map_id": "none", "name": "ASIC trimers:H+ transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2672379", "map_id": "none", "name": "amiloride", "type": "inhibitor", "sub_type": "other", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2672383", "map_id": "CHEBI:35475", "name": "NSAID", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10065963", "map_id": "E1BMN1", "name": "ASIC4", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000027364", "map_id": "ENSBTAT00000027364", "name": "ASIC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066021", "map_id": "none", "name": "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066018", "map_id": "none", "name": "NALCN:UNC79:UNC80", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LL71", "map_id": "A0A3Q1LL71", "name": "NALCN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082451", "map_id": "ENSBTAT00000082451", "name": "NALCN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N0G4", "map_id": "G3N0G4", "name": "UNC79", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065331", "map_id": "ENSBTAT00000065331", "name": "UNC79", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJ95", "map_id": "F1MJ95", "name": "UNC80", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020495", "map_id": "ENSBTAT00000020495", "name": "UNC80", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066277", "map_id": "none", "name": "SLC17A3-2 transports cytosolic urate to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10066274", "map_id": "Q17QE9", "name": "SLC17A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10065991", "map_id": "none", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065988", "map_id": "none", "name": "ANOs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MCG6", "map_id": "A0A3Q1MCG6", "name": "ANO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LNC2", "map_id": "A0A3Q1LNC2", "name": "ANO9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071379", "map_id": "ENSBTAT00000071379", "name": "ANO9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MUE0", "map_id": "A0A3Q1MUE0", "name": "ANO3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078140", "map_id": "ENSBTAT00000078140", "name": "ANO3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049035", "map_id": "none", "name": "G13 activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049028", "map_id": "none", "name": "TP receptor:Thromboxane A2:G-protein G13 (inactive)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049032", "map_id": "none", "name": "TP receptor:Thromboxane A2:G-protein G13 (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10091701", "map_id": "none", "name": "AAMP binds to TBXA2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091699", "map_id": "none", "name": "TBXA2R-alpha,TBXA2R-beta:AAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049014", "map_id": "none", "name": "Gq activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049009", "map_id": "none", "name": "TP receptor:Thromboxane A2:G-protein Gq (inactive)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10049011", "map_id": "none", "name": "TP receptor:Thromboxane A2:G-protein Gq (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10048059", "map_id": "none", "name": "Interaction of Nectins with Afadin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10048055", "map_id": "none", "name": "Nectin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MUF6", "map_id": "F1MUF6", "name": "NECTIN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032332", "map_id": "ENSBTAT00000032332", "name": "NECTIN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048049", "map_id": "A0A3Q1LN46", "name": "AFDN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000083796", "map_id": "ENSBTAT00000083796", "name": "AFDN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048057", "map_id": "none", "name": "Nectin:afadin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LN46", "map_id": "A0A3Q1LN46", "name": "AFDN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048045", "map_id": "none", "name": "Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_140648", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048041", "map_id": "none", "name": "Classic Cadherin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BIA5", "map_id": "E1BIA5", "name": "CDH10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084008", "map_id": "ENSBTAT00000084008", "name": "CDH10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BQ10", "map_id": "E1BQ10", "name": "CDH24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015083", "map_id": "ENSBTAT00000015083", "name": "CDH24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDQ6", "map_id": "A2VDQ6", "name": "CDH11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081011", "map_id": "ENSBTAT00000081011", "name": "CDH11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MW29", "map_id": "F1MW29", "name": "CDH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020042", "map_id": "ENSBTAT00000020042", "name": "CDH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MB78", "map_id": "A0A3Q1MB78", "name": "CDH15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075672", "map_id": "ENSBTAT00000075672", "name": "CDH15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BF53", "map_id": "E1BF53", "name": "CDH7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031089", "map_id": "ENSBTAT00000031089", "name": "CDH7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DJ5", "map_id": "Q08DJ5", "name": "CDH18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031090", "map_id": "ENSBTAT00000031090", "name": "CDH18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZM2", "map_id": "G3MZM2", "name": "CDH8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065042", "map_id": "ENSBTAT00000065042", "name": "CDH8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048043", "map_id": "none", "name": "Cadherin trans-homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "reaction_10048348", "map_id": "none", "name": "Transhomodimerization of Nectin-like (Necl) proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10048344", "map_id": "none", "name": "Necl-1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M7P7", "map_id": "A0A3Q1M7P7", "name": "CADM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070841", "map_id": "ENSBTAT00000070841", "name": "CADM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048346", "map_id": "none", "name": "Necl-1/Necl-2/Necl-3 trans homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "reaction_10048065", "map_id": "none", "name": "Transhomodimerization of Nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10048061", "map_id": "none", "name": "Nectin cis-homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10048063", "map_id": "none", "name": "Nectin trans homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "reaction_10048334", "map_id": "none", "name": "Necl-1:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10048053", "map_id": "F1MUF6", "name": "NECTIN3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048330", "map_id": "A0A3Q1M7P7", "name": "CADM3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10048332", "map_id": "none", "name": "Necl-1:Nectin-3 trans heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "reaction_10048352", "map_id": "none", "name": "PVR:PVRL3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10042235", "map_id": "A0A3Q1MRJ9", "name": "NECTIN2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000070790", "map_id": "ENSBTAT00000070790", "name": "NECTIN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10048350", "map_id": "none", "name": "PRV:PVRL3 trans heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "A0A3Q1MRJ9", "map_id": "A0A3Q1MRJ9", "name": "NECTIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048342", "map_id": "none", "name": "Nectin-2:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_204883", "compartment_display": "cell junction" }, { "id": "species_10048338", "map_id": "none", "name": "Nectin-2 cis homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10048336", "map_id": "none", "name": "PVRL3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10048340", "map_id": "none", "name": "Nectin-2:PVRL3 transheterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_204883", "compartment_display": "cell junction", "complex": "true" }, { "id": "reaction_10049335", "map_id": "none", "name": "Cis-homodimerization of nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10044043", "map_id": "none", "name": "Interaction of PECAM-1 and SHP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044014", "map_id": "A0A3Q1MHJ9", "name": "phospho-PECAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10044041", "map_id": "none", "name": "PECAM-1:SHP-2 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049290", "map_id": "none", "name": "Fgr may phosphorylate p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049037", "map_id": "A0A3Q1LTT9", "name": "MAPK14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040563", "map_id": "A0A3Q1LTT9", "name": "phospho-MAPK14", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049287", "map_id": "A5PKG9", "name": "FGR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10049283", "map_id": "none", "name": "PECAM-1 binds PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049281", "map_id": "none", "name": "p-PECAM:PP2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044018", "map_id": "none", "name": "Interaction of PECAM-1 and SHP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044016", "map_id": "none", "name": "PECAM-1:SHP-1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049364", "map_id": "none", "name": "PECAM1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044026", "map_id": "A0A3Q1MHJ9", "name": "PECAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10085323", "map_id": "none", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8869214", "map_id": "CHEBI:52450", "name": "PAF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8869207", "map_id": "CHEBI:91144", "name": "lyso-PAF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10085320", "map_id": "P79106", "name": "PAFAH2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000006727", "map_id": "ENSBTAT00000006727", "name": "PAFAH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10048182", "map_id": "none", "name": "Binding of ATP to P2X receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037602", "map_id": "none", "name": "P2RX receptors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10072426", "map_id": "none", "name": "ASAP1 stimulates GTPase activity of ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10072421", "map_id": "none", "name": "RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1LHY8", "map_id": "A0A3Q1LHY8", "name": "RAB11FIP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075339", "map_id": "ENSBTAT00000075339", "name": "RAB11FIP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6P5", "map_id": "A0A3Q1M6P5", "name": "RAB11A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067242", "map_id": "ENSBTAT00000067242", "name": "RAB11A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072423", "map_id": "none", "name": "RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10072399", "map_id": "none", "name": "ARF4:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072401", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072322", "map_id": "none", "name": "ARF4:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072326", "map_id": "none", "name": "ARF4:GTP binds VxPx-motifs of membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_5623403", "map_id": "P02699", "name": "Rho", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10072324", "map_id": "none", "name": "ARF4:GTP:VxPx-containing ciliary membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10072475", "map_id": "none", "name": "ARL6:GTP and the BBSome target cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_261122", "compartment_display": "ciliary membrane" }, { "id": "species_10072451", "map_id": "none", "name": "ARL6:GTP:BBSome:ciliary cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q0IIM2", "map_id": "Q0IIM2", "name": "ARL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013306", "map_id": "ENSBTAT00000013306", "name": "ARL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MU26", "map_id": "F1MU26", "name": "BBS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032389", "map_id": "ENSBTAT00000032389", "name": "BBS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BHJ5", "map_id": "E1BHJ5", "name": "BBS9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008587", "map_id": "ENSBTAT00000008587", "name": "BBS9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1JQ97", "map_id": "Q1JQ97", "name": "BBS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010013", "map_id": "ENSBTAT00000010013", "name": "BBS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4X0", "map_id": "F1N4X0", "name": "TTC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042964", "map_id": "ENSBTAT00000042964", "name": "TTC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLF9", "map_id": "A6QLF9", "name": "BBS5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014216", "map_id": "ENSBTAT00000014216", "name": "BBS5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N2W1", "map_id": "G3N2W1", "name": "BBIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064380", "map_id": "ENSBTAT00000064380", "name": "BBIP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BN34", "map_id": "E1BN34", "name": "BBS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026844", "map_id": "ENSBTAT00000026844", "name": "BBS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MB52", "map_id": "F1MB52", "name": "BBS7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006505", "map_id": "ENSBTAT00000006505", "name": "BBS7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072467", "map_id": "none", "name": "ARL6:GTP:BBSome:ciliary cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_261122", "compartment_display": "ciliary membrane", "complex": "true" }, { "id": "species_10072473", "map_id": "none", "name": "LZTFL1 oligomer:BBSome", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072435", "map_id": "none", "name": "Formation of the BBSome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072245", "map_id": "F1MB52", "name": "BBS7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072229", "map_id": "E1BN34", "name": "BBS1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072257", "map_id": "G3N2W1", "name": "BBIP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072241", "map_id": "A6QLF9", "name": "BBS5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072253", "map_id": "F1N4X0", "name": "TTC8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072237", "map_id": "Q1JQ97", "name": "BBS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072249", "map_id": "E1BHJ5", "name": "BBS9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072233", "map_id": "F1MU26", "name": "BBS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10072259", "map_id": "none", "name": "BBSome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072453", "map_id": "none", "name": "ARL6:GTP and the BBSome bind ciliary cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072449", "map_id": "none", "name": "BBSome ciliary cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072441", "map_id": "none", "name": "ARL6:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10057569", "map_id": "none", "name": "Activation of voltage gated Potassium channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057566", "map_id": "none", "name": "Octamer of Voltage gated K+ channels", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q4PJK1", "map_id": "Q4PJK1", "name": "KCNAB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024576", "map_id": "ENSBTAT00000024576", "name": "KCNAB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDT0", "map_id": "A2VDT0", "name": "KCNAB3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019888", "map_id": "ENSBTAT00000019888", "name": "KCNAB3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7K3", "map_id": "E1B7K3", "name": "KCNA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064709", "map_id": "ENSBTAT00000064709", "name": "KCNA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLD6", "map_id": "F1MLD6", "name": "KCNA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022142", "map_id": "ENSBTAT00000022142", "name": "KCNA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTJ1", "map_id": "F1MTJ1", "name": "KCNA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009938", "map_id": "ENSBTAT00000009938", "name": "KCNA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0E8", "map_id": "F1N0E8", "name": "KCNA10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010960", "map_id": "ENSBTAT00000010960", "name": "KCNA10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N1T8", "map_id": "G3N1T8", "name": "KCNA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065475", "map_id": "ENSBTAT00000065475", "name": "KCNA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKB0", "map_id": "F1MKB0", "name": "KCNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020543", "map_id": "ENSBTAT00000020543", "name": "KCNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B9N0", "map_id": "E1B9N0", "name": "KCNA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021458", "map_id": "ENSBTAT00000021458", "name": "KCNA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MFH2", "map_id": "A0A3Q1MFH2", "name": "KCNQ2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086274", "map_id": "ENSBTAT00000086274", "name": "KCNQ2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MPE6", "map_id": "A0A3Q1MPE6", "name": "KCNQ4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074581", "map_id": "ENSBTAT00000074581", "name": "KCNQ4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BDC5", "map_id": "E1BDC5", "name": "KCNB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039169", "map_id": "ENSBTAT00000039169", "name": "KCNB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML52", "map_id": "F1ML52", "name": "KCNG4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022193", "map_id": "ENSBTAT00000022193", "name": "KCNG4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MJA9", "map_id": "F1MJA9", "name": "KCNG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018162", "map_id": "ENSBTAT00000018162", "name": "KCNG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BCM0", "map_id": "E1BCM0", "name": "KCNG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004406", "map_id": "ENSBTAT00000004406", "name": "KCNG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MC54", "map_id": "F1MC54", "name": "KCNG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046307", "map_id": "ENSBTAT00000046307", "name": "KCNG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MP51", "map_id": "F1MP51", "name": "KCNH5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015122", "map_id": "ENSBTAT00000015122", "name": "KCNH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MPV7", "map_id": "F1MPV7", "name": "KCNS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010214", "map_id": "ENSBTAT00000010214", "name": "KCNS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BKI8", "map_id": "E1BKI8", "name": "KCNS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011681", "map_id": "ENSBTAT00000011681", "name": "KCNS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N553", "map_id": "F1N553", "name": "KCNC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007132", "map_id": "ENSBTAT00000007132", "name": "KCNC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M6H7", "map_id": "A0A3Q1M6H7", "name": "KCNC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071160", "map_id": "ENSBTAT00000071160", "name": "KCNC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FV89", "map_id": "A4FV89", "name": "KCNF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028357", "map_id": "ENSBTAT00000028357", "name": "KCNF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXZ4", "map_id": "F1MXZ4", "name": "KCNV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011219", "map_id": "ENSBTAT00000011219", "name": "KCNV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BII8", "map_id": "E1BII8", "name": "KCNV2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023770", "map_id": "ENSBTAT00000023770", "name": "KCNV2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B760", "map_id": "E1B760", "name": "KCNH3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025668", "map_id": "ENSBTAT00000025668", "name": "KCNH3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLH0", "map_id": "E1BLH0", "name": "KCNH4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005335", "map_id": "ENSBTAT00000005335", "name": "KCNH4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDM5", "map_id": "F1MDM5", "name": "KCNH8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017003", "map_id": "ENSBTAT00000017003", "name": "KCNH8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BMA2", "map_id": "E1BMA2", "name": "KCNH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022102", "map_id": "ENSBTAT00000022102", "name": "KCNH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057365", "map_id": "none", "name": "Activation of Ca2+ activated Potassium channels with small conductance", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057362", "map_id": "none", "name": "Small conductance Ca2+ activated potassium channel", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BGY2", "map_id": "E1BGY2", "name": "KCNN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011376", "map_id": "ENSBTAT00000011376", "name": "KCNN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N467", "map_id": "F1N467", "name": "KCNN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014706", "map_id": "ENSBTAT00000014706", "name": "KCNN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057665", "map_id": "none", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057662", "map_id": "none", "name": "TRESK homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MW24", "map_id": "F1MW24", "name": "KCNK18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020046", "map_id": "ENSBTAT00000020046", "name": "KCNK18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057656", "map_id": "none", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057653", "map_id": "none", "name": "TASK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N1D1", "map_id": "G3N1D1", "name": "KCNK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063834", "map_id": "ENSBTAT00000063834", "name": "KCNK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057682", "map_id": "none", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057679", "map_id": "none", "name": "TALK 1and 2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q8HZT2", "map_id": "Q8HZT2", "name": "KCNK17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013646", "map_id": "ENSBTAT00000013646", "name": "KCNK17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BEH1", "map_id": "E1BEH1", "name": "KCNK16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000030656", "map_id": "ENSBTAT00000030656", "name": "KCNK16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057616", "map_id": "none", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10057613", "map_id": "none", "name": "THIK1 homodimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3N1Q6", "map_id": "G3N1Q6", "name": "KCNK13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000065420", "map_id": "ENSBTAT00000065420", "name": "KCNK13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090498", "map_id": "none", "name": "CYPs hydroxylate DHA to 14(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9027049", "map_id": "CHEBI:137346", "name": "14(R)-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090495", "map_id": "none", "name": "CYP1A2,2C8,2C9,2D6,2E1,3A4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10084300", "map_id": "none", "name": "MYLIP dimer ubiquitinates VLDLR on Lys-839", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10084266", "map_id": "A0A3Q1M988", "name": "VLDLR", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071362", "map_id": "ENSBTAT00000071362", "name": "VLDLR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084295", "map_id": "A0A3Q1M988", "name": "VLDLR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10084297", "map_id": "none", "name": "MYLIP dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10045642", "map_id": "Q5E9B6", "name": "NR1H3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10083113", "map_id": "none", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_163579", "map_id": "CHEBI:17002", "name": "CHEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_8876730", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_216762", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "false" }, { "id": "species_10083110", "map_id": "Q1JQE6", "name": "NCEH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000026745", "map_id": "ENSBTAT00000026745", "name": "NCEH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085994", "map_id": "none", "name": "NPC2 binds CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10085990", "map_id": "P79345", "name": "NPC2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_8848047", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10085992", "map_id": "none", "name": "NPC2:CHOL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10086026", "map_id": "none", "name": "SOAT1,2 transfer acyl group to CHOL forming CHEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8876704", "map_id": "CHEBI:17002", "name": "CHEST", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10086023", "map_id": "Q3T0N9", "name": "SOAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000033962", "map_id": "ENSBTAT00000033962", "name": "SOAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086557", "map_id": "none", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10086554", "map_id": "F1MI11", "name": "CES3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000056670", "map_id": "ENSBTAT00000056670", "name": "CES3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086002", "map_id": "none", "name": "NPC2 transfers CHOL to NPC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10085998", "map_id": "A0A3Q1LT67", "name": "NPC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "ENSBTAT00000085568", "map_id": "ENSBTAT00000085568", "name": "NPC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086000", "map_id": "none", "name": "NPC1:CHOL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "A0A3Q1LT67", "map_id": "A0A3Q1LT67", "name": "NPC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086004", "map_id": "none", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10044020", "map_id": "none", "name": "Interaction of GPVI and FceRI gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037447", "map_id": "G3MX19", "name": "GP6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000065426", "map_id": "ENSBTAT00000065426", "name": "GP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037453", "map_id": "none", "name": "FCERIG dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037455", "map_id": "none", "name": "GP VI : FceRI gamma dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MX19", "map_id": "G3MX19", "name": "GP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049300", "map_id": "none", "name": "GPVI binds Fyn and Lyn", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037463", "map_id": "F1N261", "name": "LYN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037465", "map_id": "none", "name": "GPVI:FceRI gamma:FYN:LYN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040521", "map_id": "none", "name": "Association of Cks1 with SCF(Skp2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10040517", "map_id": "Q0P5A5", "name": "CKS1B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000033975", "map_id": "ENSBTAT00000033975", "name": "CKS1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040513", "map_id": "none", "name": "CUL1:SKP1:SKP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10040519", "map_id": "none", "name": "CUL1:SKP1:SKP2:CKS1B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0P5A5", "map_id": "Q0P5A5", "name": "CKS1B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040542", "map_id": "none", "name": "Ubiquitination of phospho-p27/p21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10040537", "map_id": "none", "name": "Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A5PKM2", "map_id": "A5PKM2", "name": "CDKN1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011001", "map_id": "ENSBTAT00000011001", "name": "CDKN1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040539", "map_id": "none", "name": "Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10040576", "map_id": "none", "name": "Translocation of p21 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10040572", "map_id": "A5PKM2", "name": "CDKN1A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040574", "map_id": "A5PKM2", "name": "CDKN1A", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10040503", "map_id": "none", "name": "Translocation of p27 to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10040501", "map_id": "A6QLS3", "name": "CDKN1B", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10033512", "map_id": "none", "name": "Cdt1 associates with geminin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10033414", "map_id": "A0A3Q1LIW5", "name": "CDT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10033508", "map_id": "Q56JZ0", "name": "GMNN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10033510", "map_id": "none", "name": "Cdt1:geminin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10033466", "map_id": "none", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10033462", "map_id": "none", "name": "DNA polymerase epsilon", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BIF0", "map_id": "E1BIF0", "name": "POLE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009882", "map_id": "ENSBTAT00000009882", "name": "POLE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZN5", "map_id": "Q3SZN5", "name": "POLE3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000316", "map_id": "ENSBTAT00000000316", "name": "POLE3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQ14", "map_id": "A6QQ14", "name": "POLE4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047798", "map_id": "ENSBTAT00000047798", "name": "POLE4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_68419", "map_id": "none", "name": "origin of replication", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10033464", "map_id": "none", "name": "DNA polymerase epsilon:origin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087385", "map_id": "none", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087381", "map_id": "none", "name": "Cyclin D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087383", "map_id": "none", "name": "CDK4,CDK6:CCND", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10056616", "map_id": "none", "name": "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056566", "map_id": "none", "name": "E2F4,E2F5:TFDP1,TFDP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10056614", "map_id": "E1BMR3", "name": "phospho-RBL1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10056599", "map_id": "none", "name": "p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10057816", "map_id": "none", "name": "Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056564", "map_id": "A0A3Q1M1Y7", "name": "phospho-RBL2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10057814", "map_id": "none", "name": "p-T401,S672,1035-RBL2:SCF(Skp2):Cks1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056602", "map_id": "none", "name": "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10057821", "map_id": "none", "name": "Ubiquitination of p130 (RBL2) by SCF (Skp2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10057818", "map_id": "none", "name": "Ub-p-T401,S672,1035-RBL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087487", "map_id": "none", "name": "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087392", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087465", "map_id": "none", "name": "CDK4/6:CCND:p-Y77-CDKN1A,p-Y88-CDKN1B,(p-Y91-CDKN1C)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087484", "map_id": "none", "name": "(p-Y342-PTK6,p-Y397-LYN,p-Y226,Y393-ABL1,p-Y419-SRC,p-5Y-JAK2)", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10087503", "map_id": "none", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10087491", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10087501", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10087394", "map_id": "none", "name": "Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10087390", "map_id": "none", "name": "CDKN1A,CDKN1B,(CDKN1C)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10065794", "map_id": "none", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065782", "map_id": "none", "name": "CK2 Phosphorylated Condensin I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N3G4", "map_id": "F1N3G4", "name": "phospho-NCAPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019603", "map_id": "ENSBTAT00000019603", "name": "phospho-NCAPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MH70", "map_id": "F1MH70", "name": "phospho-NCAPH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017174", "map_id": "ENSBTAT00000017174", "name": "phospho-NCAPH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065792", "map_id": "none", "name": "Condensin I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_2529006", "map_id": "none", "name": "Unknown Phosphatase", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035745", "map_id": "none", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10035737", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10035743", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10035747", "map_id": "none", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10035731", "map_id": "A0A452DIV3", "name": "phospho-CCND1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035739", "map_id": "A0A452DIV3", "name": "phospho-CCND1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10074692", "map_id": "none", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074688", "map_id": "F6R5E4", "name": "phospho-CHEK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10074690", "map_id": "none", "name": "p-T68-CHEK2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F6R5E4", "map_id": "F6R5E4", "name": "phospho-CHEK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074695", "map_id": "none", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10051465", "map_id": "none", "name": "Mis18 complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10051445", "map_id": "none", "name": "Mis18 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BMQ3", "map_id": "E1BMQ3", "name": "MIS18BP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003380", "map_id": "ENSBTAT00000003380", "name": "MIS18BP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D7N9", "map_id": "A5D7N9", "name": "MIS18A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022106", "map_id": "ENSBTAT00000022106", "name": "MIS18A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAL2", "map_id": "E1BAL2", "name": "OIP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014256", "map_id": "ENSBTAT00000014256", "name": "OIP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051395", "map_id": "none", "name": "CCAN:DNA:CASC5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M302", "map_id": "A0A3Q1M302", "name": "KNL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068526", "map_id": "ENSBTAT00000068526", "name": "KNL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A8WFK5", "map_id": "A8WFK5", "name": "CENPW", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000048435", "map_id": "ENSBTAT00000048435", "name": "CENPW", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MLG9", "map_id": "F1MLG9", "name": "CENPK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061053", "map_id": "ENSBTAT00000061053", "name": "CENPK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EA18", "map_id": "Q5EA18", "name": "CENPL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009094", "map_id": "ENSBTAT00000009094", "name": "CENPL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NKU0", "map_id": "Q2NKU0", "name": "CENPX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005369", "map_id": "ENSBTAT00000005369", "name": "CENPX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DW5", "map_id": "Q08DW5", "name": "CENPQ", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027600", "map_id": "ENSBTAT00000027600", "name": "CENPQ", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BAK5", "map_id": "E1BAK5", "name": "CENPC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001748", "map_id": "ENSBTAT00000001748", "name": "CENPC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MXW4", "map_id": "G3MXW4", "name": "CENPT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064627", "map_id": "ENSBTAT00000064627", "name": "CENPT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZBK8", "map_id": "Q3ZBK8", "name": "CENPO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032953", "map_id": "ENSBTAT00000032953", "name": "CENPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7YWP8", "map_id": "A7YWP8", "name": "CENPP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068875", "map_id": "ENSBTAT00000068875", "name": "CENPP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBR7", "map_id": "Q2TBR7", "name": "CENPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017996", "map_id": "ENSBTAT00000017996", "name": "CENPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LTH6", "map_id": "A0A3Q1LTH6", "name": "CENPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039939", "map_id": "ENSBTAT00000039939", "name": "CENPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051453", "map_id": "none", "name": "CCAN:DNA:CASC5:Mis18 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10051451", "map_id": "none", "name": "RSF complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10051447", "map_id": "none", "name": "CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G5E613", "map_id": "G5E613", "name": "CENPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049496", "map_id": "ENSBTAT00000049496", "name": "CENPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BB33", "map_id": "E1BB33", "name": "HJURP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042677", "map_id": "ENSBTAT00000042677", "name": "HJURP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBG8", "map_id": "A7MBG8", "name": "RUVBL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027964", "map_id": "ENSBTAT00000027964", "name": "RUVBL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051335", "map_id": "none", "name": "RSF Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LP30", "map_id": "A0A3Q1LP30", "name": "RSF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083436", "map_id": "ENSBTAT00000083436", "name": "RSF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051431", "map_id": "none", "name": "HJURP:NPM1:RBBP4:RBBP7:RUVBL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10051449", "map_id": "none", "name": "CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10051461", "map_id": "none", "name": "New CENPA-containing nucleosomes are deposited at the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035218", "map_id": "none", "name": "Histone H2B", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10051459", "map_id": "none", "name": "CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10035105", "map_id": "none", "name": "Histone H2A", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10051463", "map_id": "none", "name": "HJURP:CENPA complex localizes to the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10051457", "map_id": "none", "name": "HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10058792", "map_id": "none", "name": "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10057070", "map_id": "none", "name": "Hemoglobin A binds O2, releasing H+ and CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10063560", "map_id": "none", "name": "SREBP1A,1C,2:Importin beta-1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10043501", "map_id": "none", "name": "RAN:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10060344", "map_id": "none", "name": "SREBP1A,1C,2:Importin beta-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M285", "map_id": "A0A3Q1M285", "name": "SREBF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072870", "map_id": "ENSBTAT00000072870", "name": "SREBF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML06", "map_id": "F1ML06", "name": "SREBF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018956", "map_id": "ENSBTAT00000018956", "name": "SREBF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063558", "map_id": "none", "name": "Importin-beta:Ran GTP complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10060342", "map_id": "none", "name": "SREBP1A,1C,2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10063562", "map_id": "none", "name": "SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060328", "map_id": "none", "name": "SREBF1A,1C,2 cleaved by S2P", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10060330", "map_id": "none", "name": "SREBP1A,1C,2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060346", "map_id": "none", "name": "SREBP1A,1C,2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060332", "map_id": "none", "name": "SREBP1A,1C,2:Importin beta-1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10063564", "map_id": "none", "name": "SREBP1A,1C,2 binds Importin beta-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090604", "map_id": "none", "name": "TYSND1 cleaves TYSND1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_10090597", "map_id": "E1BF31", "name": "TYSND1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "ENSBTAT00000052816", "map_id": "ENSBTAT00000052816", "name": "TYSND1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090599", "map_id": "E1BF31", "name": "TYSND1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10090601", "map_id": "E1BF31", "name": "TYSND1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10037293", "map_id": "none", "name": "Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037287", "map_id": "none", "name": "DIABLO:XIAP:Caspase-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MD58", "map_id": "F1MD58", "name": "CASP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008706", "map_id": "ENSBTAT00000008706", "name": "CASP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NL36", "map_id": "Q2NL36", "name": "DIABLO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005496", "map_id": "ENSBTAT00000005496", "name": "DIABLO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037229", "map_id": "none", "name": "Caspase-7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10037291", "map_id": "none", "name": "DIABLO dimer:XIAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090504", "map_id": "none", "name": "PTGS2 dimer oxidises DHA to 13-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9027547", "map_id": "CHEBI:72608", "name": "13-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090506", "map_id": "none", "name": "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9027614", "map_id": "CHEBI:136352", "name": "17-HDPAn-3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090508", "map_id": "none", "name": "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9027622", "map_id": "CHEBI:72637", "name": "17-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090510", "map_id": "none", "name": "PTGS2 dimer oxidises EPA to PGH3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9028280", "map_id": "CHEBI:134407", "name": "PGH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10075037", "map_id": "none", "name": "SIRT6 deacetylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075030", "map_id": "none", "name": "Ac-K432,K526,K604-RBBP8 homotetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075034", "map_id": "A5D7K6", "name": "SIRT6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000026521", "map_id": "ENSBTAT00000026521", "name": "SIRT6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074798", "map_id": "none", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074795", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S327,T847-RBBP8:p-S1981,Ac-K3016-ATM:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074789", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S327,T847,T859-RBBP8:p-S1981,Ac-K3016-ATM:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076339", "map_id": "none", "name": "Initial resection of double-strand break ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076336", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-BRCA1-C complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075051", "map_id": "none", "name": "3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10060476", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10060456", "map_id": "F1MK34", "name": "PI4K2B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000047316", "map_id": "ENSBTAT00000047316", "name": "PI4K2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083369", "map_id": "none", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_2239407", "map_id": "CHEBI:60479", "name": "lysophosphatidylcholine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_6814794", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083366", "map_id": "F1N5C8", "name": "ENPP6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000015375", "map_id": "ENSBTAT00000015375", "name": "ENPP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083211", "map_id": "none", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10083208", "map_id": "E1BMJ5", "name": "PNPLA6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000084401", "map_id": "ENSBTAT00000084401", "name": "PNPLA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082931", "map_id": "none", "name": "TMEM55B translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_10082927", "map_id": "Q17QI9", "name": "PIP4P1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "ENSBTAT00000003561", "map_id": "ENSBTAT00000003561", "name": "PIP4P1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082929", "map_id": "Q17QI9", "name": "PIP4P1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10083092", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6810408", "map_id": "CHEBI:16500", "name": "PI5P", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10083089", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10082934", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10060569", "map_id": "none", "name": "PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060566", "map_id": "none", "name": "PIK3(2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MDQ5", "map_id": "F1MDQ5", "name": "PIK3R3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003878", "map_id": "ENSBTAT00000003878", "name": "PIK3R3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B8D1", "map_id": "E1B8D1", "name": "PIK3C2G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043102", "map_id": "ENSBTAT00000043102", "name": "PIK3C2G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBU9", "map_id": "F1MBU9", "name": "PIK3C2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017388", "map_id": "ENSBTAT00000017388", "name": "PIK3C2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060473", "map_id": "none", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060470", "map_id": "none", "name": "PIP5K1A/B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10082136", "map_id": "none", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10082132", "map_id": "A7MB43", "name": "MTMR9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000004852", "map_id": "ENSBTAT00000004852", "name": "MTMR9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082128", "map_id": "F1ME94", "name": "MTMR8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000050192", "map_id": "ENSBTAT00000050192", "name": "MTMR8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082134", "map_id": "none", "name": "MTMR8:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1ME94", "map_id": "F1ME94", "name": "MTMR8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MB43", "map_id": "A7MB43", "name": "MTMR9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060600", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806224", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10060532", "map_id": "none", "name": "MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LYK5", "map_id": "A0A3Q1LYK5", "name": "MTMR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069408", "map_id": "ENSBTAT00000069408", "name": "MTMR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085784", "map_id": "none", "name": "p-Y281,292-RUFY1 binds PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10085767", "map_id": "F6R352", "name": "phospho-RUFY1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "ENSBTAT00000000317", "map_id": "ENSBTAT00000000317", "name": "phospho-RUFY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1806200", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_10085782", "map_id": "none", "name": "p-Y281,292-RUFY1:PI3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "F6R352", "map_id": "F6R352", "name": "phospho-RUFY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060572", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806276", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10060595", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060592", "map_id": "none", "name": "INPP5(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QNM5", "map_id": "A6QNM5", "name": "INPP5K", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015257", "map_id": "ENSBTAT00000015257", "name": "INPP5K", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLB5", "map_id": "E1BLB5", "name": "INPP5J", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022635", "map_id": "ENSBTAT00000022635", "name": "INPP5J", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085780", "map_id": "none", "name": "BMX phosphorylates RUFY1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085777", "map_id": "F6R352", "name": "RUFY1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10085773", "map_id": "F6R352", "name": "phospho-RUFY1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044855", "map_id": "G3X680", "name": "BMX", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000000488", "map_id": "ENSBTAT00000000488", "name": "BMX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060535", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10082152", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10082149", "map_id": "none", "name": "MTMR6:MTMR9,MTMR8:MTMR9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10082155", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10060429", "map_id": "none", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10060461", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060458", "map_id": "none", "name": "PI4K2A/2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MK34", "map_id": "F1MK34", "name": "PI4K2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLN5", "map_id": "A6QLN5", "name": "PI4K2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002604", "map_id": "ENSBTAT00000002604", "name": "PI4K2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085775", "map_id": "none", "name": "p-Y281,292-RUFY1 translocates from cytosol to early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10060590", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060585", "map_id": "A0A3Q1LSR1", "name": "INPP4B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000079052", "map_id": "ENSBTAT00000079052", "name": "INPP4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085697", "map_id": "none", "name": "PLEKHA4,(5,6) bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10085693", "map_id": "none", "name": "PLEKHA4,(5,6)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B7V8", "map_id": "E1B7V8", "name": "PLEKHA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061135", "map_id": "ENSBTAT00000061135", "name": "PLEKHA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085695", "map_id": "none", "name": "PLEKHA4,(5,6):PI3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10060579", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060576", "map_id": "none", "name": "PIP4K2/5K1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10082147", "map_id": "none", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060526", "map_id": "A0A3Q1LYK5", "name": "MTMR6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10082145", "map_id": "none", "name": "MTMR6:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060514", "map_id": "none", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060511", "map_id": "none", "name": "INPP5(2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060550", "map_id": "none", "name": "PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10060547", "map_id": "none", "name": "PIK3C(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10083800", "map_id": "none", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8849959", "map_id": "none", "name": "PI(4,5)P2, PI(3,4)P2, PI(3,4,5)P3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_8849958", "map_id": "none", "name": "PI5P, PI3P, PI(3,5)P2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "species_1806205", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_1806259", "map_id": "CHEBI:16500", "name": "PI5P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10083797", "map_id": "F1MCQ6", "name": "INPP5F", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "ENSBTAT00000029059", "map_id": "ENSBTAT00000029059", "name": "INPP5F", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060588", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10060558", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10060574", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806199", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10060501", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10060518", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10060614", "map_id": "none", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10060611", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806230", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1806217", "map_id": "CHEBI:17526", "name": "PI4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10060608", "map_id": "none", "name": "TPTE2-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1MHQ7", "map_id": "A0A3Q1MHQ7", "name": "TPTE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081928", "map_id": "ENSBTAT00000081928", "name": "TPTE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060483", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806165", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10060480", "map_id": "E1BAU6", "name": "INPP5E", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000001784", "map_id": "ENSBTAT00000001784", "name": "INPP5E", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060498", "map_id": "none", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10060495", "map_id": "none", "name": "PIK3C2A/G", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10060597", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524146", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10060516", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806159", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10085843", "map_id": "none", "name": "TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane" }, { "id": "species_8874484", "map_id": "none", "name": "PI(4,5)P2, PI(3,4,5)P3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_437051", "compartment_display": "cytoplasmic vesicle membrane", "complex": "true" }, { "id": "species_8874460", "map_id": "none", "name": "PI(4,5)P2, PI(3,4,5)P3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10085840", "map_id": "none", "name": "TNFAIP8 proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LVF0", "map_id": "A0A3Q1LVF0", "name": "TNFAIP8L3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072298", "map_id": "ENSBTAT00000072298", "name": "TNFAIP8L3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040152", "map_id": "none", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176575", "map_id": "CHEBI:17263", "name": "E1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176501", "map_id": "CHEBI:17474", "name": "E1S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158466", "map_id": "CHEBI:17985", "name": "PAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040149", "map_id": "none", "name": "SULT1E1,2A1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZC30", "map_id": "Q3ZC30", "name": "SULT1E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015862", "map_id": "ENSBTAT00000015862", "name": "SULT1E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BG19", "map_id": "E1BG19", "name": "LOC514658", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000031917", "map_id": "ENSBTAT00000031917", "name": "LOC514658", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0S6", "map_id": "F1N0S6", "name": "SULT2A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028234", "map_id": "ENSBTAT00000028234", "name": "SULT2A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040120", "map_id": "none", "name": "lithocholate + PAPS => lithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176555", "map_id": "CHEBI:35421", "name": "lithocholate sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040087", "map_id": "none", "name": "SULT2A1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040122", "map_id": "none", "name": "taurolithocholate + PAPS => taurolithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176565", "map_id": "CHEBI:17179", "name": "taurolithocholate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040157", "map_id": "none", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176566", "map_id": "CHEBI:17931", "name": "N-hydroxy-2-acetylaminofluorene", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176500", "map_id": "CHEBI:35424", "name": "AAF-N-S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040154", "map_id": "none", "name": "SULTs active on NH2AAF", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MP36", "map_id": "A0A3Q1MP36", "name": "SULT1C4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072780", "map_id": "ENSBTAT00000072780", "name": "SULT1C4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBP4", "map_id": "F1MBP4", "name": "SULT1C2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003629", "map_id": "ENSBTAT00000003629", "name": "SULT1C2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50227", "map_id": "P50227", "name": "SULT1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011388", "map_id": "ENSBTAT00000011388", "name": "SULT1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076799", "map_id": "none", "name": "ABHD14B hydrolyses PNPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5695960", "map_id": "CHEBI:85867", "name": "PNPB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5695950", "map_id": "CHEBI:16836", "name": "PNP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076796", "map_id": "A7YY28", "name": "ABHD14B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024782", "map_id": "ENSBTAT00000024782", "name": "ABHD14B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038320", "map_id": "none", "name": "SULT1A1 dimer sulfonates NHABP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158847", "map_id": "CHEBI:16580", "name": "NHABP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158859", "map_id": "CHEBI:32701", "name": "NHABP-SO4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10038228", "map_id": "none", "name": "SULT1A1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040112", "map_id": "none", "name": "SULTs transfer (SO4)2- group to PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176665", "map_id": "CHEBI:35420", "name": "PREGS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040109", "map_id": "none", "name": "SULTs active on pregnenolone", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A1A4N6", "map_id": "A1A4N6", "name": "SULT2B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063187", "map_id": "ENSBTAT00000063187", "name": "SULT2B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040147", "map_id": "none", "name": "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176600", "map_id": "CHEBI:35422", "name": "p-nitrophenol sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040144", "map_id": "none", "name": "SULT1A1,A2,C2,4A1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040115", "map_id": "none", "name": "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176492", "map_id": "CHEBI:4866", "name": "E2-SO4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040075", "map_id": "none", "name": "SULT1E1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040117", "map_id": "none", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176667", "map_id": "CHEBI:28774", "name": "T3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176564", "map_id": "CHEBI:35432", "name": "3,5,3'-triiodothyronine 4-sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040095", "map_id": "none", "name": "SULT dimers (T2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZX9", "map_id": "F1MZX9", "name": "SULT6B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011474", "map_id": "ENSBTAT00000011474", "name": "SULT6B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038231", "map_id": "none", "name": "SULT1A1 dimer sulfonates PARA to PARA-SO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158469", "map_id": "CHEBI:46195", "name": "PARA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158472", "map_id": "CHEBI:32635", "name": "PARA-SO4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10088617", "map_id": "none", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10088606", "map_id": "E1B8G6", "name": "PODXL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "ENSBTAT00000043559", "map_id": "ENSBTAT00000043559", "name": "PODXL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088610", "map_id": "E1B8G6", "name": "PODXL2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10040136", "map_id": "none", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176496", "map_id": "CHEBI:16814", "name": "DHEA-SO4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040133", "map_id": "none", "name": "SULTs active on DHEA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040107", "map_id": "none", "name": "SULTs transfer (SO4)2- group to 27HCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176617", "map_id": "CHEBI:17703", "name": "27HCHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_176502", "map_id": "CHEBI:35419", "name": "27HCHOL3S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040104", "map_id": "none", "name": "SULT2B1-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10038318", "map_id": "none", "name": "Phenol can form a sulfate conjugate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158858", "map_id": "CHEBI:15882", "name": "PhOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158850", "map_id": "CHEBI:27905", "name": "Phenyl sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040129", "map_id": "none", "name": "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040126", "map_id": "Q3ZCK3", "name": "BPNT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000005311", "map_id": "ENSBTAT00000005311", "name": "BPNT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040131", "map_id": "none", "name": "cholesterol + PAPS => cholesterol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176478", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176618", "map_id": "CHEBI:41321", "name": "cholesterol sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040098", "map_id": "none", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176486", "map_id": "CHEBI:35430", "name": "3,3'-diiodothyronine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_176519", "map_id": "CHEBI:35431", "name": "3,3'-diiodothyronine 4-sulfate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10038340", "map_id": "none", "name": "SULT1A3,4 dimers sulfate DA to DAOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_159352", "map_id": "CHEBI:37946", "name": "DAOS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10088580", "map_id": "none", "name": "IMPAD1 hydrolyses PAP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851226", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_8953493", "map_id": "CHEBI:16027", "name": "adenosine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10088577", "map_id": "none", "name": "IMPAD1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "A0A452DIR7", "map_id": "A0A452DIR7", "name": "BPNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020766", "map_id": "ENSBTAT00000020766", "name": "BPNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050342", "map_id": "none", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_450444", "map_id": "none", "name": "mRNA Transcript Targeted by AUF1(hnRNP D0)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050336", "map_id": "none", "name": "AUF1 Dimer (isoform p37 or p40)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M8I4", "map_id": "A0A3Q1M8I4", "name": "HNRNPD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075547", "map_id": "ENSBTAT00000075547", "name": "HNRNPD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050340", "map_id": "none", "name": "AUF1 Tetramer: Destabilized mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10082923", "map_id": "none", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069400", "map_id": "G3MY31", "name": "ING2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000066213", "map_id": "ENSBTAT00000066213", "name": "ING2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10082921", "map_id": "none", "name": "ING2:PI5P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "G3MY31", "map_id": "G3MY31", "name": "ING2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086155", "map_id": "none", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086151", "map_id": "none", "name": "p-S326-PIP4K2B dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086153", "map_id": "none", "name": "p-S326-PIP4K2B dimers:PIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10083072", "map_id": "none", "name": "ING2 recruits EP300 to TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10083070", "map_id": "none", "name": "ING2:EP300:p-S15,S20-TP53 Tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10083077", "map_id": "none", "name": "ING2-bound EP300 acetylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10083074", "map_id": "none", "name": "ING2:EP300:Ac-K382,p-S15,S20-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090593", "map_id": "none", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090579", "map_id": "Q08DL6", "name": "PEX7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022338", "map_id": "ENSBTAT00000022338", "name": "PEX7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090589", "map_id": "none", "name": "Cargo proteins containing PTS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NBU3", "map_id": "A0A3Q1NBU3", "name": "AGPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081070", "map_id": "ENSBTAT00000081070", "name": "AGPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090591", "map_id": "none", "name": "PEX7:Cargo proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08DL6", "map_id": "Q08DL6", "name": "PEX7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090770", "map_id": "none", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10090766", "map_id": "none", "name": "Class I Peroxisomal Membrane Proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A4FUD4", "map_id": "A4FUD4", "name": "PEX12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026285", "map_id": "ENSBTAT00000026285", "name": "PEX12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1S5", "map_id": "A0A3Q1M1S5", "name": "PXMP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047447", "map_id": "ENSBTAT00000047447", "name": "PXMP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MTZ2", "map_id": "A0A3Q1MTZ2", "name": "PEX14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074727", "map_id": "ENSBTAT00000074727", "name": "PEX14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q148K5", "map_id": "Q148K5", "name": "PEX11B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011022", "map_id": "ENSBTAT00000011022", "name": "PEX11B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MSZ7", "map_id": "A0A3Q1MSZ7", "name": "PEX26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082884", "map_id": "ENSBTAT00000082884", "name": "PEX26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQZ0", "map_id": "A6QQZ0", "name": "GDAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016739", "map_id": "ENSBTAT00000016739", "name": "GDAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DI69", "map_id": "A0A452DI69", "name": "PXMP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009885", "map_id": "ENSBTAT00000009885", "name": "PXMP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090732", "map_id": "Q3SZD1", "name": "PEX19", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000009921", "map_id": "ENSBTAT00000009921", "name": "PEX19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10090768", "map_id": "none", "name": "PEX19:class I PMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SZD1", "map_id": "Q3SZD1", "name": "PEX19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039049", "map_id": "none", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10039039", "map_id": "none", "name": "ATPase:ADP:Pi", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10039044", "map_id": "none", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10039041", "map_id": "none", "name": "ATPase:ATP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10039047", "map_id": "none", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10035417", "map_id": "none", "name": "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10035374", "map_id": "none", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73911", "map_id": "CHEBI:17066", "name": "bHBA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_73909", "map_id": "CHEBI:15344", "name": "ACA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10035360", "map_id": "none", "name": "BDH1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q02337", "map_id": "Q02337", "name": "BDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082799", "map_id": "ENSBTAT00000082799", "name": "BDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035415", "map_id": "none", "name": "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10035412", "map_id": "none", "name": "OXCT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LIX4", "map_id": "A0A3Q1LIX4", "name": "OXCT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077723", "map_id": "ENSBTAT00000077723", "name": "OXCT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065944", "map_id": "none", "name": "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane" }, { "id": "species_10035617", "map_id": "none", "name": "p-MII:SAG", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "A0A3Q1MAN7", "map_id": "A0A3Q1MAN7", "name": "SAG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077886", "map_id": "ENSBTAT00000077886", "name": "SAG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065942", "map_id": "none", "name": "p-RHO:SAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "species_2466098", "map_id": "CHEBI:17898", "name": "atRAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10035596", "map_id": "none", "name": "GUCYs converts GTP to cGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane" }, { "id": "species_10035583", "map_id": "F1MY40", "name": "GUCY2D", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "ENSBTAT00000011564", "map_id": "ENSBTAT00000011564", "name": "GUCY2D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035592", "map_id": "P46065", "name": "GUCA1A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000087322", "map_id": "ENSBTAT00000087322", "name": "GUCA1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035594", "map_id": "none", "name": "GCAP1:Ca2+", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P46065", "map_id": "P46065", "name": "GUCA1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035590", "map_id": "none", "name": "GUCA1A:Ca2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "reaction_10065808", "map_id": "none", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10065796", "map_id": "P04695", "name": "GNAT1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2534019", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10065799", "map_id": "P04695", "name": "GNAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10065805", "map_id": "none", "name": "NMT1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9N181", "map_id": "Q9N181", "name": "NMT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000050460", "map_id": "ENSBTAT00000050460", "name": "NMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZK0", "map_id": "F1MZK0", "name": "NMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035619", "map_id": "none", "name": "PP2A dephosphorylates p-RHO to RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane" }, { "id": "species_10035601", "map_id": "P02699", "name": "phospho-RHO", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10035607", "map_id": "none", "name": "PPEF1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MBQ1", "map_id": "F1MBQ1", "name": "PPEF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068795", "map_id": "ENSBTAT00000068795", "name": "PPEF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065940", "map_id": "none", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035588", "map_id": "P46065", "name": "GUCA1A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "reaction_10078600", "map_id": "none", "name": "LRRTMs bind NRXNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078596", "map_id": "none", "name": "LRRTMs", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10078418", "map_id": "none", "name": "NRXNs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MMZ4", "map_id": "F1MMZ4", "name": "NRXN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061495", "map_id": "ENSBTAT00000061495", "name": "NRXN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N119", "map_id": "F1N119", "name": "NRXN3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026956", "map_id": "ENSBTAT00000026956", "name": "NRXN3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078598", "map_id": "none", "name": "NRXNs:LRRTMs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078488", "map_id": "none", "name": "Protein 4.1 binds CASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10078484", "map_id": "none", "name": "Protein 4.1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LWK1", "map_id": "A0A3Q1LWK1", "name": "EPB41L2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075847", "map_id": "ENSBTAT00000075847", "name": "EPB41L2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7S3", "map_id": "E1B7S3", "name": "EPB41L3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061281", "map_id": "ENSBTAT00000061281", "name": "EPB41L3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078486", "map_id": "none", "name": "CASK:Protein 4.1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10078522", "map_id": "none", "name": "NRXNs bind CASK:Protein 4.1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078444", "map_id": "none", "name": "NRXNs:NLGN dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F6Q4B1", "map_id": "F6Q4B1", "name": "NLGN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045228", "map_id": "ENSBTAT00000045228", "name": "NLGN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7N7", "map_id": "G3X7N7", "name": "NLGN4X", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000040145", "map_id": "ENSBTAT00000040145", "name": "NLGN4X", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N104", "map_id": "F1N104", "name": "NLGN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026987", "map_id": "ENSBTAT00000026987", "name": "NLGN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078520", "map_id": "none", "name": "NRXNs:NLGN dimers:CASK:Protein 4.1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078446", "map_id": "none", "name": "NRXNs bind NLGNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078442", "map_id": "none", "name": "NLGN dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078464", "map_id": "none", "name": "Homer1,2,3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078458", "map_id": "none", "name": "HOMER1,2,3:GRM1,GRM5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LHC4", "map_id": "A0A3Q1LHC4", "name": "HOMER2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083397", "map_id": "ENSBTAT00000083397", "name": "HOMER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MW19", "map_id": "F1MW19", "name": "HOMER3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001076", "map_id": "ENSBTAT00000001076", "name": "HOMER3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078456", "map_id": "none", "name": "HOMER1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10078462", "map_id": "none", "name": "2xHOMER1,2,3:GRM1,GRM5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10078466", "map_id": "none", "name": "Homer1,2,3 binds mGluR1a,5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10045110", "map_id": "F1MDE0", "name": "GRM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10078518", "map_id": "none", "name": "ABP1 binds SHANK proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10078514", "map_id": "none", "name": "NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MV08", "map_id": "A0A3Q1MV08", "name": "DLGAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084157", "map_id": "ENSBTAT00000084157", "name": "DLGAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBJ2", "map_id": "E1BBJ2", "name": "DLGAP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006420", "map_id": "ENSBTAT00000006420", "name": "DLGAP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRW9", "map_id": "A0A3Q1LRW9", "name": "SHANK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068330", "map_id": "ENSBTAT00000068330", "name": "SHANK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043423", "map_id": "A0A452DIT4", "name": "DBNL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10078516", "map_id": "none", "name": "NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:DBNL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10046648", "map_id": "none", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10046644", "map_id": "none", "name": "RAP1A:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10046646", "map_id": "none", "name": "RAP1A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10044632", "map_id": "none", "name": "RAPGEF3:cAMP complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10044626", "map_id": "none", "name": "RAPGEF4:cAMP Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046623", "map_id": "none", "name": "cAMP activates EPAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044624", "map_id": "E1BPX7", "name": "RAPGEF4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10046642", "map_id": "none", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10046640", "map_id": "none", "name": "Potassium voltage-gated channels (beta cell, open)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10046630", "map_id": "none", "name": "cAMP activates EPAC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044630", "map_id": "A0A3Q1LHN3", "name": "RAPGEF3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10043885", "map_id": "none", "name": "VD3 binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_209767", "map_id": "CHEBI:28940", "name": "VD3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10043881", "map_id": "A0A3Q1LQ02", "name": "GC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000075079", "map_id": "ENSBTAT00000075079", "name": "GC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043883", "map_id": "none", "name": "GC:VD3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LQ02", "map_id": "A0A3Q1LQ02", "name": "GC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043903", "map_id": "none", "name": "Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043895", "map_id": "none", "name": "CUBN:GC:25(OH)D", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MKV7", "map_id": "F1MKV7", "name": "CUBN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000039417", "map_id": "ENSBTAT00000039417", "name": "CUBN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043901", "map_id": "none", "name": "CUBN:GC:25(OH)D", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10088926", "map_id": "none", "name": "VD3 dissociates from GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10043984", "map_id": "none", "name": "25(OH)D binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_209906", "map_id": "CHEBI:17933", "name": "25(OH)D", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10043982", "map_id": "none", "name": "GC:25(OH)D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10088928", "map_id": "none", "name": "CUBN dissociates from 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10044728", "map_id": "none", "name": "CUBN:25(OH)D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_350136", "map_id": "CHEBI:17933", "name": "25(OH)D", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10043899", "map_id": "F1MKV7", "name": "CUBN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10044739", "map_id": "none", "name": "LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044732", "map_id": "none", "name": "CUBN:GC:25(OH)D", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10044736", "map_id": "F1N6H1", "name": "LRP2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000005988", "map_id": "ENSBTAT00000005988", "name": "LRP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044741", "map_id": "none", "name": "CUBN binds GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10044730", "map_id": "F1MKV7", "name": "CUBN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10043910", "map_id": "none", "name": "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_350159", "map_id": "CHEBI:47828", "name": "CTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040922", "map_id": "none", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191265", "map_id": "CHEBI:15442", "name": "PSQPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191269", "map_id": "CHEBI:15440", "name": "SQNE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040919", "map_id": "none", "name": "FDFT:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q6IE76", "map_id": "Q6IE76", "name": "FDFT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016504", "map_id": "ENSBTAT00000016504", "name": "FDFT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041664", "map_id": "none", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_195691", "map_id": "CHEBI:16290", "name": "CHdOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_195655", "map_id": "CHEBI:27910", "name": "7dhDESOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041661", "map_id": "A0A3Q1MF09", "name": "SC5D", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000072112", "map_id": "ENSBTAT00000072112", "name": "SC5D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041728", "map_id": "none", "name": "Reduction of desmosterol to cholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196420", "map_id": "CHEBI:17737", "name": "DESMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041725", "map_id": "A0A3Q1M7E0", "name": "DHCR24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000080856", "map_id": "ENSBTAT00000080856", "name": "DHCR24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041671", "map_id": "none", "name": "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_194691", "map_id": "CHEBI:18252", "name": "ZYMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041668", "map_id": "Q3ZBT8", "name": "EBP", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000012234", "map_id": "ENSBTAT00000012234", "name": "EBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040892", "map_id": "none", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191409", "map_id": "CHEBI:17211", "name": "GPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191385", "map_id": "CHEBI:17407", "name": "FAPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040889", "map_id": "none", "name": "6(GGPS1:3Mg2+)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P56966", "map_id": "P56966", "name": "GGPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017376", "map_id": "ENSBTAT00000017376", "name": "GGPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040924", "map_id": "none", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10040895", "map_id": "none", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191324", "map_id": "CHEBI:16057", "name": "DMAPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041502", "map_id": "none", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194657", "map_id": "CHEBI:63844", "name": "4CZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194661", "map_id": "CHEBI:52386", "name": "ZYMONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041481", "map_id": "Q3ZBE9", "name": "NSDHL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000012167", "map_id": "ENSBTAT00000012167", "name": "NSDHL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040913", "map_id": "none", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10040910", "map_id": "none", "name": "IDI1 or 2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A140T853", "map_id": "A0A140T853", "name": "IDI1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005323", "map_id": "ENSBTAT00000005323", "name": "IDI1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040881", "map_id": "none", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191309", "map_id": "CHEBI:15441", "name": "SQOX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040878", "map_id": "none", "name": "SQLE:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A5D9A8", "map_id": "A5D9A8", "name": "SQLE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007228", "map_id": "ENSBTAT00000007228", "name": "SQLE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088019", "map_id": "none", "name": "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8952135", "map_id": "CHEBI:134117", "name": "presqualene monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088016", "map_id": "Q58DI5", "name": "PLPP6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014674", "map_id": "ENSBTAT00000014674", "name": "PLPP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041493", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_194681", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194725", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194688", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194668", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194704", "map_id": "CHEBI:18364", "name": "14DMLANOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10041490", "map_id": "A6QQV8", "name": "LBR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10083496", "map_id": "none", "name": "ACAT2 condenses 2 Ac-CoA to form ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191293", "map_id": "CHEBI:15345", "name": "ACA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10083493", "map_id": "none", "name": "ACAT2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MLP4", "map_id": "A0A3Q1MLP4", "name": "ACAT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012548", "map_id": "ENSBTAT00000012548", "name": "ACAT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040904", "map_id": "none", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191374", "map_id": "CHEBI:15467", "name": "bHMG-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191424", "map_id": "CHEBI:17710", "name": "MVA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040901", "map_id": "none", "name": "HMGCR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A7Z064", "map_id": "A7Z064", "name": "HMGCR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010315", "map_id": "ENSBTAT00000010315", "name": "HMGCR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041484", "map_id": "none", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194735", "map_id": "CHEBI:63842", "name": "4C4MZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194667", "map_id": "CHEBI:50593", "name": "dh4MZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041486", "map_id": "none", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194723", "map_id": "CHEBI:63841", "name": "4MZYMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10041474", "map_id": "A6H7G3", "name": "MSMO1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000003991", "map_id": "ENSBTAT00000003991", "name": "MSMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081986", "map_id": "none", "name": "EBP isomerizes ZYMSTNL to LTHSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6807048", "map_id": "CHEBI:16608", "name": "ZYMSTNL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6807054", "map_id": "CHEBI:17168", "name": "LTHSOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10081988", "map_id": "none", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6807057", "map_id": "CHEBI:17759", "name": "7-dehydroCHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10081990", "map_id": "none", "name": "DHCR24 reduces ZYMOL to ZYMSTNL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10041477", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10038347", "map_id": "none", "name": "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194096", "map_id": "none", "name": "cholate; chenodeoxycholate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_194073", "map_id": "none", "name": "choloyl-CoA; chenodeoxycholoyl-CoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_192356", "map_id": "CHEBI:15519", "name": "choloyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "CHEBI:28701", "map_id": "CHEBI:28701", "name": "CHEBI:28701", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041437", "map_id": "none", "name": "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10041428", "map_id": "A0A452DID8", "name": "FABP6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000014054", "map_id": "ENSBTAT00000014054", "name": "FABP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_192483", "map_id": "none", "name": "bile salts and acids", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:17687", "map_id": "CHEBI:17687", "name": "CHEBI:17687", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28865", "map_id": "CHEBI:28865", "name": "CHEBI:28865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36274", "map_id": "CHEBI:36274", "name": "CHEBI:36274", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:9407", "map_id": "CHEBI:9407", "name": "CHEBI:9407", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041430", "map_id": "none", "name": "bile salts and acids:FABP6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DID8", "map_id": "A0A452DID8", "name": "FABP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16525", "map_id": "CHEBI:16525", "name": "CHEBI:16525", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041434", "map_id": "F1N5D8", "name": "SLC10A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000021363", "map_id": "ENSBTAT00000021363", "name": "SLC10A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085806", "map_id": "none", "name": "STARD5 binds DCA, LCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10085802", "map_id": "A1A4M6", "name": "STARD5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000014559", "map_id": "ENSBTAT00000014559", "name": "STARD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085804", "map_id": "none", "name": "STARD5:DCA,LCA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A1A4M6", "map_id": "A1A4M6", "name": "STARD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10085291", "map_id": "none", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8868399", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8868400", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10085288", "map_id": "none", "name": "OSBPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LYV2", "map_id": "A0A3Q1LYV2", "name": "OSBPL6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083446", "map_id": "ENSBTAT00000083446", "name": "OSBPL6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BBD8", "map_id": "E1BBD8", "name": "OSBPL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017982", "map_id": "ENSBTAT00000017982", "name": "OSBPL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BL67", "map_id": "E1BL67", "name": "OSBPL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044841", "map_id": "ENSBTAT00000044841", "name": "OSBPL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0E7", "map_id": "A0A3Q1M0E7", "name": "OSBPL1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066543", "map_id": "ENSBTAT00000066543", "name": "OSBPL1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MW81", "map_id": "A0A3Q1MW81", "name": "OSBPL1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041097", "map_id": "none", "name": "27-hydroxycholesterol is 7alpha-hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192194", "map_id": "CHEBI:18431", "name": "Cholest-5-ene-3beta,7alpha,27-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041369", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193829", "map_id": "CHEBI:48834", "name": "5beta-cholestan-7alpha,12alpha,27-triol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193843", "map_id": "CHEBI:17278", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041371", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193835", "map_id": "CHEBI:48825", "name": "4CHOL7a,27DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041373", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9617026", "map_id": "CHEBI:48833", "name": "4CHOL7a,12a,27TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041375", "map_id": "none", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193830", "map_id": "CHEBI:48778", "name": "5beta-cholestan-7alpha,27-diol-3-one", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041377", "map_id": "none", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193842", "map_id": "CHEBI:28540", "name": "5beta-cholestan-3alpha,7alpha,26-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041208", "map_id": "none", "name": "THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192013", "map_id": "CHEBI:18402", "name": "THCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192096", "map_id": "CHEBI:37642", "name": "25(R) THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041179", "map_id": "none", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_191968", "map_id": "CHEBI:16466", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_192161", "map_id": "CHEBI:18402", "name": "THCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041210", "map_id": "none", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191980", "map_id": "CHEBI:2290", "name": "5beta-cholestan-7alpha-ol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192030", "map_id": "CHEBI:28047", "name": "5beta-cholestan-3alpha,7alpha-diol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041308", "map_id": "none", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "reaction_10041310", "map_id": "none", "name": "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193436", "map_id": "CHEBI:28047", "name": "5beta-cholestan-3alpha, 7alpha-diol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193387", "map_id": "CHEBI:28540", "name": "5beta-cholestan-3alpha,7alpha,26-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041104", "map_id": "none", "name": "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_192078", "map_id": "CHEBI:16496", "name": "5bCHOL3a,7a,12a-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_192201", "map_id": "CHEBI:17278", "name": "5bCHOL3a,7a,12a,27-tetrol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041170", "map_id": "none", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192064", "map_id": "CHEBI:2288", "name": "5beta-cholesten-7alpha, 12alpha-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192087", "map_id": "CHEBI:16496", "name": "5beta-cholestan-3alpha,7alpha,12alpha-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041301", "map_id": "none", "name": "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193442", "map_id": "CHEBI:15494", "name": "25(S) DHCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193459", "map_id": "CHEBI:27393", "name": "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10041223", "map_id": "none", "name": "ACOX2:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10041204", "map_id": "none", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192136", "map_id": "CHEBI:17899", "name": "4CHOL7aOLONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041172", "map_id": "none", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10041111", "map_id": "none", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041321", "map_id": "none", "name": "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193505", "map_id": "CHEBI:16577", "name": "DHCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193457", "map_id": "CHEBI:15494", "name": "25(R) DHCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041323", "map_id": "none", "name": "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193429", "map_id": "CHEBI:15494", "name": "25(R) DHCA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10041226", "map_id": "none", "name": "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_192316", "map_id": "CHEBI:37643", "name": "25(S) THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192342", "map_id": "CHEBI:27505", "name": "THCA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10041197", "map_id": "none", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192195", "map_id": "CHEBI:28477", "name": "4CHOL7a,12aDONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10041325", "map_id": "none", "name": "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_193435", "map_id": "CHEBI:27428", "name": "3alpha,7alpha-dihydroxy-5beta-cholestan-26-al", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_193440", "map_id": "CHEBI:16577", "name": "DHCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10041327", "map_id": "none", "name": "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10041186", "map_id": "none", "name": "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_192308", "map_id": "CHEBI:37642", "name": "25(R) THCA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10041317", "map_id": "none", "name": "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10041319", "map_id": "none", "name": "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10085316", "map_id": "none", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8868393", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10076009", "map_id": "none", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069573", "map_id": "A0A3Q1LPC8", "name": "XPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000080567", "map_id": "ENSBTAT00000080567", "name": "XPC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069565", "map_id": "Q2TBN3", "name": "CETN2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000010319", "map_id": "ENSBTAT00000010319", "name": "CETN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076007", "map_id": "none", "name": "XPC:RAD23:CETN2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2TBN3", "map_id": "Q2TBN3", "name": "CETN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LPC8", "map_id": "A0A3Q1LPC8", "name": "XPC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077396", "map_id": "none", "name": "UV-DDB ubiquitinates XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076069", "map_id": "none", "name": "XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10077087", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077108", "map_id": "none", "name": "PARP1 or PARP2 PARylates DDB2 and autoPARylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077089", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10077106", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076071", "map_id": "none", "name": "XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076067", "map_id": "none", "name": "UV-DDB:COP9 Signalosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5688114", "map_id": "none", "name": "Distorted dsDNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10076065", "map_id": "none", "name": "COP9 signalosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10077016", "map_id": "none", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077009", "map_id": "none", "name": "Ub:ERCC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q1LZ75", "map_id": "Q1LZ75", "name": "ERCC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023078", "map_id": "ENSBTAT00000023078", "name": "ERCC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036653", "map_id": "Q1LZ75", "name": "ERCC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10077013", "map_id": "E1BC35", "name": "USP45", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000067380", "map_id": "ENSBTAT00000067380", "name": "USP45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036661", "map_id": "none", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036657", "map_id": "E1BKV9", "name": "ERCC4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000046336", "map_id": "ENSBTAT00000046336", "name": "ERCC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036659", "map_id": "none", "name": "ERCC1:ERCC4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BKV9", "map_id": "E1BKV9", "name": "ERCC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037517", "map_id": "none", "name": "Fyn/Lyn-mediated phosphorylation of FcR1 gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037504", "map_id": "none", "name": "GPVI:FceRI gamma:FYN:LYN:Collagen type I", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P02453", "map_id": "P02453", "name": "COL1A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017420", "map_id": "ENSBTAT00000017420", "name": "COL1A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037514", "map_id": "none", "name": "GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049071", "map_id": "none", "name": "SLP-76 stimulates PLC gamma 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049069", "map_id": "A0A3Q1MMD9", "name": "PLCG2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10037554", "map_id": "A0A3Q1MMD9", "name": "phospho-PLCG2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10049395", "map_id": "none", "name": "PI3K alpha, beta, gamma convert PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10049426", "map_id": "none", "name": "VAV2 is a GEF for Rho/Rac family kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049418", "map_id": "none", "name": "VAV2 Rho/Rac effectors:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10049420", "map_id": "none", "name": "VAV2 Rho/Rac effectors:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10049423", "map_id": "A0A3Q1MQP9", "name": "phospho-VAV2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10037557", "map_id": "none", "name": "PLC gamma 2-mediated PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10037588", "map_id": "none", "name": "Binding of Syk tyrosine kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037586", "map_id": "none", "name": "GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10050630", "map_id": "none", "name": "p-Y348-SYK dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050628", "map_id": "none", "name": "GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10050626", "map_id": "A0A3Q1MHG9", "name": "phospho-SYK", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10047475", "map_id": "none", "name": "Gi activation by P2Y purinoceptor 12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047470", "map_id": "none", "name": "ADP:P2RY12:G-protein Gi (inactive)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10047472", "map_id": "none", "name": "ADP:P2RY12:G-protein Gi (active)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10049039", "map_id": "none", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10047985", "map_id": "none", "name": "Src activation following P2Y purinoceptor activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10047983", "map_id": "E1BIM8", "name": "phospho-SRC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10037201", "map_id": "none", "name": "Formation of Elongin BC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037197", "map_id": "Q3SZ32", "name": "TCEB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10037193", "map_id": "Q2KII4", "name": "ELOC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10037199", "map_id": "none", "name": "Elongin B:C complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10037185", "map_id": "none", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037181", "map_id": "E1BNP8", "name": "SUPT16H", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000027214", "map_id": "ENSBTAT00000027214", "name": "SUPT16H", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037177", "map_id": "A6QQT5", "name": "SSRP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000073946", "map_id": "ENSBTAT00000073946", "name": "SSRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037183", "map_id": "none", "name": "FACT complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6QQT5", "map_id": "A6QQT5", "name": "SSRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNP8", "map_id": "E1BNP8", "name": "SUPT16H", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037187", "map_id": "none", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037108", "map_id": "none", "name": "CCNT1,CCNT2,CCNK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3N172", "map_id": "G3N172", "name": "CCNK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063128", "map_id": "ENSBTAT00000063128", "name": "CCNK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MA24", "map_id": "A0A3Q1MA24", "name": "CCNT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074231", "map_id": "ENSBTAT00000074231", "name": "CCNT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037098", "map_id": "Q5EAB2", "name": "CDK9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000006162", "map_id": "ENSBTAT00000006162", "name": "CDK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037110", "map_id": "none", "name": "P-TEFb complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q5EAB2", "map_id": "Q5EAB2", "name": "CDK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037189", "map_id": "none", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10037135", "map_id": "A0A3Q1MQ76", "name": "phospho-SUPT5H", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10037130", "map_id": "A0A3Q1N7E3", "name": "SUPT4H1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10037207", "map_id": "none", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10081897", "map_id": "none", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10081893", "map_id": "A0A3Q1MXU1", "name": "SEPTIN4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000086118", "map_id": "ENSBTAT00000086118", "name": "SEPTIN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081895", "map_id": "A0A3Q1MXU1", "name": "SEPTIN4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10037264", "map_id": "none", "name": "Release of SMAC (DIABLO) from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10037260", "map_id": "Q2NL36", "name": "DIABLO", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10037262", "map_id": "Q2NL36", "name": "DIABLO", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091186", "map_id": "none", "name": "SMAC (DIABLO) forms dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037285", "map_id": "none", "name": "DIABLO dimer", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10049241", "map_id": "none", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10049243", "map_id": "none", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10049262", "map_id": "none", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049259", "map_id": "none", "name": "AQP4 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O77750", "map_id": "O77750", "name": "AQP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082069", "map_id": "ENSBTAT00000082069", "name": "AQP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049253", "map_id": "none", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10049250", "map_id": "none", "name": "p-S256-AQP2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P79099", "map_id": "P79099", "name": "phospho-AQP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011024", "map_id": "ENSBTAT00000011024", "name": "phospho-AQP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049271", "map_id": "none", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_192438", "map_id": "CHEBI:17754", "name": "glycerol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049268", "map_id": "none", "name": "AQP7 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N3R5", "map_id": "F1N3R5", "name": "AQP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026782", "map_id": "ENSBTAT00000026782", "name": "AQP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051145", "map_id": "none", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051138", "map_id": "none", "name": "AQP3,7,9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MNJ1", "map_id": "F1MNJ1", "name": "AQP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006790", "map_id": "ENSBTAT00000006790", "name": "AQP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051148", "map_id": "none", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051119", "map_id": "none", "name": "AQP10 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051150", "map_id": "none", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10051136", "map_id": "none", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10051133", "map_id": "none", "name": "AQP0,1,2,3,4,5,7,8,9,10,11,12A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3S5ZPM1", "map_id": "A0A3S5ZPM1", "name": "AQP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026884", "map_id": "ENSBTAT00000026884", "name": "AQP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P06624", "map_id": "P06624", "name": "MIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013360", "map_id": "ENSBTAT00000013360", "name": "MIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LWN9", "map_id": "A0A3Q1LWN9", "name": "AQP5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085930", "map_id": "ENSBTAT00000085930", "name": "AQP5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10051141", "map_id": "none", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10051143", "map_id": "none", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10041050", "map_id": "none", "name": "snRNA Cap hypermethylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041043", "map_id": "none", "name": "Spliceosomal m7G capped snRNAs with SMN:SM protein complex bound", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BEK3", "map_id": "E1BEK3", "name": "GEMIN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027878", "map_id": "ENSBTAT00000027878", "name": "GEMIN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KHW8", "map_id": "Q2KHW8", "name": "GEMIN6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020624", "map_id": "ENSBTAT00000020624", "name": "GEMIN6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRW7", "map_id": "F1MRW7", "name": "DDX20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024914", "map_id": "ENSBTAT00000024914", "name": "DDX20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QA0", "map_id": "Q17QA0", "name": "GEMIN7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014112", "map_id": "ENSBTAT00000014112", "name": "GEMIN7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MAW0", "map_id": "F1MAW0", "name": "GEMIN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017819", "map_id": "ENSBTAT00000017819", "name": "GEMIN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O18870", "map_id": "O18870", "name": "SMN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007547", "map_id": "ENSBTAT00000007547", "name": "SMN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJG3", "map_id": "E1BJG3", "name": "GEMIN5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016037", "map_id": "ENSBTAT00000016037", "name": "GEMIN5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1LZ79", "map_id": "Q1LZ79", "name": "GEMIN8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013582", "map_id": "ENSBTAT00000013582", "name": "GEMIN8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3ZC10", "map_id": "Q3ZC10", "name": "SNRPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010912", "map_id": "ENSBTAT00000010912", "name": "SNRPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2274", "map_id": "CHEBI:2274", "name": "CHEBI:2274", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041031", "map_id": "none", "name": "Spliceosomal m3G capped snRNAs with SMN:SM protein complex bound", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:1604", "map_id": "CHEBI:1604", "name": "CHEBI:1604", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041047", "map_id": "F1N1K9", "name": "TGS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10041039", "map_id": "none", "name": "snRNP:Snurportin complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10041035", "map_id": "Q2TBK8", "name": "SNUPN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000076267", "map_id": "ENSBTAT00000076267", "name": "SNUPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10041037", "map_id": "none", "name": "Spliceosomal m3G capped snRNA:SMN:SM:Snurportin complex ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q2TBK8", "map_id": "Q2TBK8", "name": "SNUPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039916", "map_id": "none", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_174932", "map_id": "none", "name": "N-centre functional group substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_159154", "map_id": "CHEBI:41774", "name": "TAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "CHEBI:17688", "map_id": "CHEBI:17688", "name": "CHEBI:17688", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_174918", "map_id": "none", "name": "N-glucuronide", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:63860", "map_id": "CHEBI:63860", "name": "CHEBI:63860", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:32663", "map_id": "CHEBI:32663", "name": "CHEBI:32663", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038333", "map_id": "A0A3Q1M423", "name": "UGT1A6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000076879", "map_id": "ENSBTAT00000076879", "name": "UGT1A6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076785", "map_id": "none", "name": "ABHD10 hydrolyses MPAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5694574", "map_id": "CHEBI:64689", "name": "AMPAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5694569", "map_id": "CHEBI:15748", "name": "GlcA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5694565", "map_id": "CHEBI:168396", "name": "MPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10076782", "map_id": "Q5E9H9", "name": "ABHD10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000006038", "map_id": "ENSBTAT00000006038", "name": "ABHD10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038336", "map_id": "none", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_159160", "map_id": "CHEBI:16427", "name": "BMG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_159149", "map_id": "CHEBI:18392", "name": "BDG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10038338", "map_id": "none", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10039749", "map_id": "none", "name": "UDP-glucose is oxidised to UDP-glucuronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039746", "map_id": "none", "name": "6xUGDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P12378", "map_id": "P12378", "name": "UGDH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019302", "map_id": "ENSBTAT00000019302", "name": "UGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040682", "map_id": "none", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189466", "map_id": "CHEBI:356416", "name": "dALA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10040679", "map_id": "none", "name": "ALAS1 homodimer (pyridoxal phosphate cofactor)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A452DI36", "map_id": "A0A452DI36", "name": "ALAS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005380", "map_id": "ENSBTAT00000005380", "name": "ALAS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_189444", "map_id": "CHEBI:17627", "name": "heme", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10040654", "map_id": "none", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189411", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189480", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189478", "map_id": "CHEBI:15435", "name": "PPGEN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10040651", "map_id": "none", "name": "2xCPO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "E1BKY9", "map_id": "E1BKY9", "name": "CPOX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005398", "map_id": "ENSBTAT00000005398", "name": "CPOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040688", "map_id": "none", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190173", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10040669", "map_id": "none", "name": "8x(ALAD:Zn2+)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10040686", "map_id": "none", "name": "8xALAD:Pb2+:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10040672", "map_id": "none", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189489", "map_id": "CHEBI:356416", "name": "dALA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189464", "map_id": "CHEBI:58126", "name": "PBG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10066416", "map_id": "none", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162257", "map_id": "CHEBI:17407", "name": "FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2995328", "map_id": "CHEBI:24480", "name": "heme O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10066413", "map_id": "A5D7D6", "name": "COX10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "ENSBTAT00000020336", "map_id": "ENSBTAT00000020336", "name": "COX10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040645", "map_id": "none", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189449", "map_id": "CHEBI:57845", "name": "HMBL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10040642", "map_id": "none", "name": "HMBS:DIPY", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:36319", "map_id": "CHEBI:36319", "name": "CHEBI:36319", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KIN5", "map_id": "Q2KIN5", "name": "HMBS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007052", "map_id": "ENSBTAT00000007052", "name": "HMBS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040663", "map_id": "none", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189463", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10040660", "map_id": "none", "name": "2xPPOX:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "P56602", "map_id": "P56602", "name": "PPOX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061124", "map_id": "ENSBTAT00000061124", "name": "PPOX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038380", "map_id": "none", "name": "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159559", "map_id": "CHEBI:16914", "name": "SAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159557", "map_id": "CHEBI:32587", "name": "Salicylate-CoA thioester", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10038377", "map_id": "none", "name": "ACSM2B-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A7MBE6", "map_id": "A7MBE6", "name": "ACSM2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038382", "map_id": "none", "name": "salicylate-CoA + glycine => salicyluric acid + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159572", "map_id": "CHEBI:9008", "name": "SUA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10083864", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870906", "map_id": "CHEBI:16862", "name": "NDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8870962", "map_id": "CHEBI:26558", "name": "NMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10083858", "map_id": "none", "name": "NTPDase3:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LNT1", "map_id": "A0A3Q1LNT1", "name": "ENTPD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085096", "map_id": "ENSBTAT00000085096", "name": "ENTPD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083852", "map_id": "none", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936166", "map_id": "none", "name": "ATP,GTP,CTP,ITP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:16039", "map_id": "CHEBI:16039", "name": "CHEBI:16039", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8851092", "map_id": "none", "name": "ADP,GDP,CDP,IDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10083849", "map_id": "none", "name": "NTPDase2:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "G3MZH7", "map_id": "G3MZH7", "name": "ENTPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063714", "map_id": "ENSBTAT00000063714", "name": "ENTPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083873", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851224", "map_id": "none", "name": "UDP,GDP,CDP,dTDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "CHEBI:18075", "map_id": "CHEBI:18075", "name": "CHEBI:18075", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8851227", "map_id": "none", "name": "UMP,GMP,CMP,dTMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_109366", "map_id": "CHEBI:17013", "name": "TMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10083870", "map_id": "none", "name": "NTPDase4:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1M496", "map_id": "A0A3Q1M496", "name": "ENTPD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071190", "map_id": "ENSBTAT00000071190", "name": "ENTPD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083889", "map_id": "none", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8851462", "map_id": "none", "name": "CDP,GDP,IDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851461", "map_id": "none", "name": "CMP,GMP,IMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10083886", "map_id": "none", "name": "NTPDase6:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q2KJI4", "map_id": "Q2KJI4", "name": "ENTPD6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081265", "map_id": "ENSBTAT00000081265", "name": "ENTPD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083861", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870907", "map_id": "CHEBI:17326", "name": "NTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10083876", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851233", "map_id": "none", "name": "UTP,GTP,CTP,dTTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10083926", "map_id": "none", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen" }, { "id": "species_8851517", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851509", "map_id": "none", "name": "CTP,GTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851513", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851518", "map_id": "none", "name": "CDP,GDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_10083923", "map_id": "none", "name": "NTPDase7:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "G3MYV7", "map_id": "G3MYV7", "name": "ENTPD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000062934", "map_id": "ENSBTAT00000062934", "name": "ENTPD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066684", "map_id": "none", "name": "USP7 deubiquitinates TP53 and counteracts MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066681", "map_id": "F1N556", "name": "USP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10081541", "map_id": "none", "name": "RNF34 or RFFL ubiquitinates phosphorylated TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081534", "map_id": "none", "name": "PolyUb,p-S15,S20-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10081538", "map_id": "F1MII9", "name": "RFFL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000083405", "map_id": "ENSBTAT00000083405", "name": "RFFL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066737", "map_id": "none", "name": "L3MBTL1 binds TP53 monomethylated on K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066733", "map_id": "none", "name": "Me-K382,p-S15,S20-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066728", "map_id": "A0A3Q1M5Y5", "name": "L3MBTL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000069634", "map_id": "ENSBTAT00000069634", "name": "L3MBTL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066735", "map_id": "none", "name": "L3MBTL1:Me-K382,p-S-15,S20-TP53", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M5Y5", "map_id": "A0A3Q1M5Y5", "name": "L3MBTL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081877", "map_id": "none", "name": "SETD9 methylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081870", "map_id": "none", "name": "Me1-K372,p-S15,S20-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10081874", "map_id": "F1MWB0", "name": "SETD9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000052840", "map_id": "ENSBTAT00000052840", "name": "SETD9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066724", "map_id": "none", "name": "BRD7 binds TP53 and EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066720", "map_id": "A6QLF6", "name": "BRD7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000067101", "map_id": "ENSBTAT00000067101", "name": "BRD7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066722", "map_id": "none", "name": "BRD7:p-S15,S20-TP53:EP300", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A6QLF6", "map_id": "A6QLF6", "name": "BRD7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072550", "map_id": "none", "name": "BRD7 promotes EP300-mediated acetylation of TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072547", "map_id": "none", "name": "BRD7:Ac-K382,p-S15,S20-TP53:EP300", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10080811", "map_id": "none", "name": "TP53 family members bind PPP1R13B or TP53BP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10080807", "map_id": "none", "name": "PPP1R13B,TP53BP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1LWL2", "map_id": "A0A3Q1LWL2", "name": "PPP1R13B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083195", "map_id": "ENSBTAT00000083195", "name": "PPP1R13B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1NE67", "map_id": "A0A3Q1NE67", "name": "TP53BP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082457", "map_id": "ENSBTAT00000082457", "name": "TP53BP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10078666", "map_id": "none", "name": "p-S15,S20-TP53,TP63,TP73", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G3X6J7", "map_id": "G3X6J7", "name": "TP73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007643", "map_id": "ENSBTAT00000007643", "name": "TP73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080809", "map_id": "none", "name": "(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10081530", "map_id": "none", "name": "TP53 binds POU4F2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081526", "map_id": "E1BLU8", "name": "POU4F2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000007421", "map_id": "ENSBTAT00000007421", "name": "POU4F2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081528", "map_id": "none", "name": "p-S15,S20-TP53 Tetramer:POU4F2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BLU8", "map_id": "E1BLU8", "name": "POU4F2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10080797", "map_id": "none", "name": "TP53 binds PPP1R13L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10080793", "map_id": "A0A3Q1M2S9", "name": "PPP1R13L", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000070207", "map_id": "ENSBTAT00000070207", "name": "PPP1R13L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10080795", "map_id": "none", "name": "(p-S15,S20-TP53,TP63,TP73):PPP1R13L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M2S9", "map_id": "A0A3Q1M2S9", "name": "PPP1R13L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066764", "map_id": "none", "name": "PHF20 binds TP53 dimethylated on K370 and K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10066754", "map_id": "E1BMS9", "name": "PHF20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000007321", "map_id": "ENSBTAT00000007321", "name": "phospho-PHF20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066760", "map_id": "none", "name": "Me2-K370,K382-TP53 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10066762", "map_id": "none", "name": "PHF20:Me2-K370,K382-TP53 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BMS9", "map_id": "E1BMS9", "name": "phospho-PHF20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10081889", "map_id": "none", "name": "p-S291-PHF20 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081885", "map_id": "E1BMS9", "name": "phospho-PHF20", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10081887", "map_id": "E1BMS9", "name": "phospho-PHF20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10081522", "map_id": "none", "name": "TP53 binds POU4F1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10081518", "map_id": "A0A3Q1MTW2", "name": "POU4F1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000077824", "map_id": "ENSBTAT00000077824", "name": "POU4F1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10081520", "map_id": "none", "name": "p-S15,S20-TP53 Tetramer:POU4F1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MTW2", "map_id": "A0A3Q1MTW2", "name": "POU4F1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10078474", "map_id": "none", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10078470", "map_id": "E1BB52", "name": "CDK13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10037102", "map_id": "G3N172", "name": "CCNK", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10078472", "map_id": "none", "name": "CCNK:CDK13", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10072571", "map_id": "none", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072563", "map_id": "none", "name": "PRDX1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q5E947", "map_id": "Q5E947", "name": "PRDX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004751", "map_id": "ENSBTAT00000004751", "name": "PRDX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072568", "map_id": "none", "name": "HOOS-C52-PRDX1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072557", "map_id": "none", "name": "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072554", "map_id": "Q1JQA7", "name": "TIGAR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000022146", "map_id": "ENSBTAT00000022146", "name": "TIGAR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072591", "map_id": "none", "name": "SESN1,2,3 bind overoxidized PRDX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072587", "map_id": "none", "name": "SESN1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q58CN8", "map_id": "Q58CN8", "name": "SESN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042886", "map_id": "ENSBTAT00000042886", "name": "SESN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBI2", "map_id": "A7MBI2", "name": "SESN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034532", "map_id": "ENSBTAT00000034532", "name": "SESN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072589", "map_id": "none", "name": "SESN1,2,3:HOOS-C52-PRDX1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072595", "map_id": "none", "name": "SESN1,2,3 bind AMPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072593", "map_id": "none", "name": "SESN1,2,3:p-AMPK heterotrimer:AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072614", "map_id": "none", "name": "DDIT4 binds 14-3-3 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10072610", "map_id": "Q08E62", "name": "DDIT4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000000187", "map_id": "ENSBTAT00000000187", "name": "DDIT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072612", "map_id": "none", "name": "DDIT4:14-3-3 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q08E62", "map_id": "Q08E62", "name": "DDIT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053210", "map_id": "none", "name": "ATP4A/12A:ATP4B exchanges K+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10053207", "map_id": "none", "name": "ATP4A/12A:ATP4B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MXW4", "map_id": "F1MXW4", "name": "ATP4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011569", "map_id": "ENSBTAT00000011569", "name": "ATP4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M1C8", "map_id": "A0A3Q1M1C8", "name": "ATP12A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073742", "map_id": "ENSBTAT00000073742", "name": "ATP12A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BLX8", "map_id": "E1BLX8", "name": "ATP4B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026587", "map_id": "ENSBTAT00000026587", "name": "ATP4B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053258", "map_id": "none", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_947594", "map_id": "none", "name": "APLs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane", "complex": "true" }, { "id": "species_947588", "map_id": "none", "name": "APLs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane", "complex": "true" }, { "id": "species_10053255", "map_id": "none", "name": "P-type ATPases type IV", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MZ89", "map_id": "F1MZ89", "name": "ATP10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035192", "map_id": "ENSBTAT00000035192", "name": "ATP10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MCF3", "map_id": "A0A3Q1MCF3", "name": "ATP10D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082277", "map_id": "ENSBTAT00000082277", "name": "ATP10D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M082", "map_id": "A0A3Q1M082", "name": "ATP8B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075591", "map_id": "ENSBTAT00000075591", "name": "ATP8B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3G6", "map_id": "F1N3G6", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021914", "map_id": "ENSBTAT00000021914", "name": "ATP11C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076172", "map_id": "none", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1981162", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10076169", "map_id": "F1MYA8", "name": "ATP13A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000009383", "map_id": "ENSBTAT00000009383", "name": "ATP13A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076179", "map_id": "none", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692450", "map_id": "CHEBI:36916", "name": "cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692484", "map_id": "CHEBI:36916", "name": "cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10076176", "map_id": "F1MF00", "name": "ATP13A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000010946", "map_id": "ENSBTAT00000010946", "name": "ATP13A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053143", "map_id": "none", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10053140", "map_id": "none", "name": "ATP2C1/2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "A0A3Q1LYD6", "map_id": "A0A3Q1LYD6", "name": "ATP2C2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086525", "map_id": "ENSBTAT00000086525", "name": "ATP2C2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071254", "map_id": "none", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5252122", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5252016", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071251", "map_id": "none", "name": "ATP13A4, 5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N272", "map_id": "F1N272", "name": "ATP13A4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021694", "map_id": "ENSBTAT00000021694", "name": "ATP13A4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M0A4", "map_id": "A0A3Q1M0A4", "name": "ATP13A5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077002", "map_id": "ENSBTAT00000077002", "name": "ATP13A5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057787", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_379721", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10057762", "map_id": "none", "name": "2 Iron:FXN:NFS1:ISD11:ISCU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q0VCG0", "map_id": "Q0VCG0", "name": "LYRM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000044551", "map_id": "ENSBTAT00000044551", "name": "LYRM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05B87", "map_id": "Q05B87", "name": "FXN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001725", "map_id": "ENSBTAT00000001725", "name": "FXN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q17QE6", "map_id": "Q17QE6", "name": "ISCU", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015648", "map_id": "ENSBTAT00000015648", "name": "ISCU", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057776", "map_id": "none", "name": "FDX1,FDX2 (reduced)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33738", "map_id": "CHEBI:33738", "name": "CHEBI:33738", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P00257", "map_id": "P00257", "name": "FDX1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015660", "map_id": "ENSBTAT00000015660", "name": "FDX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05B51", "map_id": "Q05B51", "name": "FDX2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013630", "map_id": "ENSBTAT00000013630", "name": "FDX2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057778", "map_id": "none", "name": "FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33739", "map_id": "CHEBI:33739", "name": "CHEBI:33739", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057784", "map_id": "none", "name": "FDX1,FDX2 (oxidized)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33737", "map_id": "CHEBI:33737", "name": "CHEBI:33737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057792", "map_id": "none", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113531", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10057790", "map_id": "none", "name": "FXN:ISD11:NFS1:ISCU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10086272", "map_id": "none", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10086254", "map_id": "none", "name": "GLRX5:2Fe-2S", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A6QLZ6", "map_id": "A6QLZ6", "name": "GLRX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017860", "map_id": "ENSBTAT00000017860", "name": "GLRX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086264", "map_id": "none", "name": "ISCA1:ISCA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q3SZG8", "map_id": "Q3SZG8", "name": "ISCA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079550", "map_id": "ENSBTAT00000079550", "name": "ISCA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBG7", "map_id": "Q2TBG7", "name": "ISCA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029272", "map_id": "ENSBTAT00000029272", "name": "ISCA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086252", "map_id": "A6QLZ6", "name": "GLRX5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10086266", "map_id": "none", "name": "ISCA1:ISCA2:4Fe-4S", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10086270", "map_id": "F1MLK9", "name": "HSCB", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000044111", "map_id": "ENSBTAT00000044111", "name": "HSCB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070682", "map_id": "none", "name": "RIPK1:RIPK3 oligomer binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070678", "map_id": "E1BGC6", "name": "MLKL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10067320", "map_id": "none", "name": "p-S-RIPK1:p-S199,227-RIPK3 oligomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10072346", "map_id": "none", "name": "MLKL binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10072328", "map_id": "none", "name": "RIP1:RIP3:MLKL oligomer:PIPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10072338", "map_id": "none", "name": "p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:FLOT1:FLOT2", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q08DN8", "map_id": "Q08DN8", "name": "FLOT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013135", "map_id": "ENSBTAT00000013135", "name": "FLOT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070684", "map_id": "none", "name": "RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10067318", "map_id": "none", "name": "p-S166-RIPK1:p-S199,227-RIPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070689", "map_id": "none", "name": "RIPK3 phosphorylates MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10070531", "map_id": "none", "name": "RIPK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070524", "map_id": "none", "name": "RIPK1:RIPK3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10070526", "map_id": "none", "name": "p-S-RIPK1:RIPK3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10070529", "map_id": "none", "name": "RIPK1:RIPK3:sorafenib, ponatinib, pazopanib", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10070534", "map_id": "none", "name": "RIPK3 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061064", "map_id": "none", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629731", "map_id": "CHEBI:18169", "name": "I3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060935", "map_id": "none", "name": "IMPA1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P20456", "map_id": "P20456", "name": "IMPA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015548", "map_id": "ENSBTAT00000015548", "name": "IMPA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZI8", "map_id": "A0A3Q1LZI8", "name": "IMPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077982", "map_id": "ENSBTAT00000077982", "name": "IMPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061067", "map_id": "none", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629753", "map_id": "CHEBI:18384", "name": "I4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060986", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629739", "map_id": "CHEBI:17816", "name": "I(1,4)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10060509", "map_id": "E1BLB5", "name": "INPP5J", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060938", "map_id": "none", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_870330", "map_id": "CHEBI:18297", "name": "I1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10061134", "map_id": "none", "name": "I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994123", "map_id": "CHEBI:18228", "name": "I(1,3,4)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629746", "map_id": "CHEBI:28858", "name": "I(3,4)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10061058", "map_id": "none", "name": "INPP1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P21327", "map_id": "P21327", "name": "INPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084681", "map_id": "ENSBTAT00000084681", "name": "INPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061061", "map_id": "none", "name": "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061014", "map_id": "none", "name": "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629769", "map_id": "CHEBI:18225", "name": "I(1,3)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10061046", "map_id": "none", "name": "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10044666", "map_id": "none", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_171095", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10044663", "map_id": "none", "name": "ABCG1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M833", "map_id": "A0A3Q1M833", "name": "ABCG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085091", "map_id": "ENSBTAT00000085091", "name": "ABCG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074493", "map_id": "none", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5682283", "map_id": "CHEBI:18059", "name": "lipids", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10074490", "map_id": "G5E556", "name": "ABCA12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000004518", "map_id": "ENSBTAT00000004518", "name": "ABCA12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046707", "map_id": "none", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_382577", "map_id": "CHEBI:15904", "name": "LCFA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_382571", "map_id": "CHEBI:15904", "name": "LCFA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10058216", "map_id": "none", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1454930", "map_id": "CHEBI:25696", "name": "organic anion", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1454919", "map_id": "CHEBI:25696", "name": "organic anion", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10058213", "map_id": "none", "name": "ABCCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LZ85", "map_id": "A0A3Q1LZ85", "name": "ABCC6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076899", "map_id": "ENSBTAT00000076899", "name": "ABCC6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BNL1", "map_id": "E1BNL1", "name": "ABCC10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007685", "map_id": "ENSBTAT00000007685", "name": "ABCC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4I6", "map_id": "F1N4I6", "name": "ABCC11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014417", "map_id": "ENSBTAT00000014417", "name": "ABCC11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3Y6", "map_id": "F1N3Y6", "name": "ABCC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026744", "map_id": "ENSBTAT00000026744", "name": "ABCC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUC1", "map_id": "F1MUC1", "name": "LOC515333", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074360", "map_id": "none", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_382539", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10074357", "map_id": "E1BLT5", "name": "ABCB4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000070307", "map_id": "ENSBTAT00000070307", "name": "ABCB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070728", "map_id": "none", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5223341", "map_id": "none", "name": "23mer peptide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5223344", "map_id": "none", "name": "23mer peptide", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10070725", "map_id": "none", "name": "ABCB9 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "A0A3Q1LZ87", "map_id": "A0A3Q1LZ87", "name": "ABCB9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070992", "map_id": "ENSBTAT00000070992", "name": "ABCB9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057832", "map_id": "none", "name": "ABCB6 transports porphyrin from cytosol to mitchondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1369066", "map_id": "CHEBI:8337", "name": "porphyrin", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1369027", "map_id": "CHEBI:8337", "name": "porphyrin", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10057829", "map_id": "none", "name": "MTABC3 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "A5D7P7", "map_id": "A5D7P7", "name": "ABCB6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027459", "map_id": "ENSBTAT00000027459", "name": "ABCB6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10046698", "map_id": "none", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10046695", "map_id": "none", "name": "Heme transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "A0A3Q1MUB7", "map_id": "A0A3Q1MUB7", "name": "ABCB7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085390", "map_id": "ENSBTAT00000085390", "name": "ABCB7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058469", "map_id": "none", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1131652", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1467459", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10058466", "map_id": "none", "name": "ABCA8/B1/B5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MB23", "map_id": "A0A3Q1MB23", "name": "ABCB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080713", "map_id": "ENSBTAT00000080713", "name": "ABCB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LS24", "map_id": "A0A3Q1LS24", "name": "ABCB5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073046", "map_id": "ENSBTAT00000073046", "name": "ABCB5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10070743", "map_id": "none", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10070739", "map_id": "A0A3Q1NB13", "name": "ABCF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070886", "map_id": "ENSBTAT00000070886", "name": "ABCF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10070741", "map_id": "none", "name": "ABCF1:EIF2S1:EIF2S2:EIF2S3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NB13", "map_id": "A0A3Q1NB13", "name": "ABCF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088584", "map_id": "none", "name": "E2F6 binds TFDP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088550", "map_id": "Q08DY6", "name": "E2F6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000028703", "map_id": "ENSBTAT00000028703", "name": "E2F6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10056555", "map_id": "A0A3Q1MKK9", "name": "TFDP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10088582", "map_id": "none", "name": "E2F6:TFDP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q08DY6", "map_id": "Q08DY6", "name": "E2F6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088554", "map_id": "none", "name": "E2F6 binds TFDP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10056551", "map_id": "Q17QZ4", "name": "TFDP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10088552", "map_id": "none", "name": "E2F6:TFDP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089578", "map_id": "none", "name": "E2F6 forms the PRC1L4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089554", "map_id": "E1BJL2", "name": "PCGF6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000013026", "map_id": "ENSBTAT00000013026", "name": "PCGF6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089550", "map_id": "A6H7C4", "name": "CBX3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000076903", "map_id": "ENSBTAT00000076903", "name": "CBX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066826", "map_id": "none", "name": "RING1,RNF2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10081545", "map_id": "A0A3Q1MS74", "name": "L3MBTL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000085264", "map_id": "ENSBTAT00000085264", "name": "L3MBTL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089576", "map_id": "none", "name": "PRC1L4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MS74", "map_id": "A0A3Q1MS74", "name": "L3MBTL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6H7C4", "map_id": "A6H7C4", "name": "CBX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BJL2", "map_id": "E1BJL2", "name": "PCGF6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088564", "map_id": "none", "name": "E2F6:TFDP1 binds to MGA:MAX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088560", "map_id": "none", "name": "MGA:MAX", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BKB7", "map_id": "E1BKB7", "name": "MGA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020143", "map_id": "ENSBTAT00000020143", "name": "MGA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MV00", "map_id": "A0A3Q1MV00", "name": "MAX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069877", "map_id": "ENSBTAT00000069877", "name": "MAX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088562", "map_id": "none", "name": "E2F6:TFDP1:MGA:MAX", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10088596", "map_id": "none", "name": "E2F6 binds the PRC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088592", "map_id": "none", "name": "PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BMR4", "map_id": "E1BMR4", "name": "PCGF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077318", "map_id": "ENSBTAT00000077318", "name": "PCGF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LF83", "map_id": "A0A3Q1LF83", "name": "RYBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077335", "map_id": "ENSBTAT00000077335", "name": "RYBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10088586", "map_id": "none", "name": "E2F6:(TFDP1,TFDP2)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10088594", "map_id": "none", "name": "E2F6:(TFDP1,TFDP2):PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10089574", "map_id": "none", "name": "CBX3 and PRC1.6 associate with E2F6.com-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10089570", "map_id": "none", "name": "E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N093", "map_id": "F1N093", "name": "EHMT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016118", "map_id": "ENSBTAT00000016118", "name": "EHMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089560", "map_id": "none", "name": "PRC1.6 (PCGF6:L3MBTL2:RING1,RNF2:YAF2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0VC56", "map_id": "Q0VC56", "name": "YAF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000064422", "map_id": "ENSBTAT00000064422", "name": "YAF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10089572", "map_id": "none", "name": "E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10091049", "map_id": "none", "name": "FOXO4 binds ATXN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10042669", "map_id": "A6QLP0", "name": "FOXO4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10091047", "map_id": "none", "name": "FOXO4:ATXN3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10091096", "map_id": "none", "name": "SIRT1,SIRT3 deacetylate FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091084", "map_id": "F1N4K5", "name": "FOXO3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10042665", "map_id": "F1N4K5", "name": "FOXO3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10091093", "map_id": "none", "name": "SIRT1,SIRT3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "G5E521", "map_id": "G5E521", "name": "SIRT3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002648", "map_id": "ENSBTAT00000002648", "name": "SIRT3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091089", "map_id": "none", "name": "KAT2B,EP300 acetylate FOXO3 under oxidative stress", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091086", "map_id": "none", "name": "KAT2B,(EP300)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10091184", "map_id": "none", "name": "CREBBP binds FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091182", "map_id": "none", "name": "FOXO1:CREBBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A452DJI7", "map_id": "A0A452DJI7", "name": "FOXO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091017", "map_id": "none", "name": "AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10042696", "map_id": "none", "name": "p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N4K5", "map_id": "F1N4K5", "name": "phospho-FOXO3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091015", "map_id": "none", "name": "p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091033", "map_id": "none", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091013", "map_id": "A6QLP0", "name": "phospho-FOXO4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10037662", "map_id": "none", "name": "YWHAZ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091031", "map_id": "none", "name": "p-T32,S197,S262-FOXO4:YWHAZ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091023", "map_id": "none", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091019", "map_id": "none", "name": "YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091021", "map_id": "none", "name": "p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091029", "map_id": "none", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091025", "map_id": "none", "name": "YWHAZ dimer,YWHAQ dimer,SFN dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091027", "map_id": "none", "name": "p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10088872", "map_id": "none", "name": "ABL1 phosphorylates YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10088870", "map_id": "F1MK73", "name": "phospho-YAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10088876", "map_id": "none", "name": "YAP1 binds TP73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10078664", "map_id": "none", "name": "TP73 Tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10088874", "map_id": "none", "name": "p-Y407-YAP1:TP73 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10088887", "map_id": "none", "name": "TP73 tetramer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10088880", "map_id": "none", "name": "TP73 Tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10086458", "map_id": "none", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086449", "map_id": "none", "name": "H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N6T0", "map_id": "F1N6T0", "name": "ZFPM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047968", "map_id": "ENSBTAT00000047968", "name": "ZFPM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BI59", "map_id": "E1BI59", "name": "GATA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004135", "map_id": "ENSBTAT00000004135", "name": "GATA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086455", "map_id": "none", "name": "H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086493", "map_id": "none", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086477", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086490", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086509", "map_id": "none", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086504", "map_id": "none", "name": "H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086506", "map_id": "none", "name": "H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086525", "map_id": "none", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086520", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086522", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086541", "map_id": "none", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086536", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086538", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086502", "map_id": "none", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086497", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086499", "map_id": "none", "name": "RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086518", "map_id": "none", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086513", "map_id": "none", "name": "H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086515", "map_id": "none", "name": "H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086534", "map_id": "none", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10086529", "map_id": "none", "name": "H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10086531", "map_id": "none", "name": "H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086638", "map_id": "none", "name": "SERPINB13 binds cathepsin L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10086634", "map_id": "E1BIP8", "name": "SERPINB13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "ENSBTAT00000005068", "map_id": "ENSBTAT00000005068", "name": "SERPINB13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063945", "map_id": "A0A452DK38", "name": "CTSL", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10086636", "map_id": "none", "name": "SERPINB13:cathepsin L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "E1BIP8", "map_id": "E1BIP8", "name": "SERPINB13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084922", "map_id": "none", "name": "TFAP2B homodimer binds YEATS4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084918", "map_id": "none", "name": "TFAP2B homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M7U2", "map_id": "A0A3Q1M7U2", "name": "TFAP2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072276", "map_id": "ENSBTAT00000072276", "name": "TFAP2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084916", "map_id": "Q32LE1", "name": "YEATS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000002913", "map_id": "ENSBTAT00000002913", "name": "YEATS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084920", "map_id": "none", "name": "TFAP2B homodimer:YEATS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q32LE1", "map_id": "Q32LE1", "name": "YEATS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084911", "map_id": "none", "name": "TFAP2C translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084905", "map_id": "Q0VC14", "name": "TFAP2C", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000002671", "map_id": "ENSBTAT00000002671", "name": "TFAP2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10066845", "map_id": "Q0VC14", "name": "TFAP2C", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10084907", "map_id": "none", "name": "TFAP2C:WWOX", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC14", "map_id": "Q0VC14", "name": "TFAP2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084895", "map_id": "none", "name": "TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084879", "map_id": "none", "name": "TFAP2 homo- and heterodimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10084891", "map_id": "none", "name": "CITED2,CITED4,(CITED1)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2HJ78", "map_id": "Q2HJ78", "name": "CITED4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020109", "map_id": "ENSBTAT00000020109", "name": "CITED4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VCT9", "map_id": "Q0VCT9", "name": "CITED2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014907", "map_id": "ENSBTAT00000014907", "name": "CITED2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084893", "map_id": "none", "name": "TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10084881", "map_id": "none", "name": "AP-2 (TFAP2) transcription factors form homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084877", "map_id": "none", "name": "TFAP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10084935", "map_id": "none", "name": "TFAP2C homodimer binds MYC and KDM5B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069764", "map_id": "F1MUR2", "name": "KDM5B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10077310", "map_id": "Q2HJ27", "name": "MYC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10066847", "map_id": "none", "name": "TFAP2C homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10084933", "map_id": "none", "name": "TFAP2C homodimer:MYC:KDM5B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10084909", "map_id": "none", "name": "WWOX binds TFAP2C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10084903", "map_id": "none", "name": "KCTD1 binds TFAP2 homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10084899", "map_id": "A0A3Q1MKM9", "name": "KCTD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000068462", "map_id": "ENSBTAT00000068462", "name": "KCTD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084901", "map_id": "none", "name": "TFAP2 homo- and heterodimers:KCTD1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MKM9", "map_id": "A0A3Q1MKM9", "name": "KCTD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063400", "map_id": "none", "name": "WWTR1 (TAZ) binds TEAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10063396", "map_id": "none", "name": "TEADs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10063398", "map_id": "none", "name": "TEAD:WWTR1(TAZ)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10063390", "map_id": "none", "name": "YAP1 binds TEAD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10063386", "map_id": "A0A3Q1N1G2", "name": "TEAD1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10063388", "map_id": "none", "name": "TEAD1:YAP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10085761", "map_id": "none", "name": "YAP1 binds TEAD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10063394", "map_id": "A0A3Q1M163", "name": "TEAD4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10085759", "map_id": "none", "name": "TEAD4:YAP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10046681", "map_id": "none", "name": "Formation of NR-NCOR Corepressor Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10045690", "map_id": "none", "name": "NR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MM20", "map_id": "A0A3Q1MM20", "name": "RORC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072859", "map_id": "ENSBTAT00000072859", "name": "RORC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M5G9", "map_id": "A0A3Q1M5G9", "name": "NR5A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069224", "map_id": "ENSBTAT00000069224", "name": "NR5A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MXG9", "map_id": "F1MXG9", "name": "NR6A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052227", "map_id": "ENSBTAT00000052227", "name": "NR6A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M9Y9", "map_id": "A0A3Q1M9Y9", "name": "RORA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073553", "map_id": "ENSBTAT00000073553", "name": "RORA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1ML62", "map_id": "F1ML62", "name": "NR2E3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018926", "map_id": "ENSBTAT00000018926", "name": "NR2E3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LKK0", "map_id": "A0A3Q1LKK0", "name": "RORB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068928", "map_id": "ENSBTAT00000068928", "name": "RORB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N5N2", "map_id": "A0A3Q1N5N2", "name": "NR3C2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070997", "map_id": "ENSBTAT00000070997", "name": "NR3C2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7YRQ5", "map_id": "Q7YRQ5", "name": "HNF4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016078", "map_id": "ENSBTAT00000016078", "name": "HNF4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MGG2", "map_id": "F1MGG2", "name": "HNF4G", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010892", "map_id": "ENSBTAT00000010892", "name": "HNF4G", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3S5ZPB3", "map_id": "A0A3S5ZPB3", "name": "NR1I3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012145", "map_id": "ENSBTAT00000012145", "name": "NR1I3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q04752", "map_id": "Q04752", "name": "NR5A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011869", "map_id": "ENSBTAT00000011869", "name": "NR5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZI4", "map_id": "A0A3Q1LZI4", "name": "ESRRG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074991", "map_id": "ENSBTAT00000074991", "name": "ESRRG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G5E5I7", "map_id": "G5E5I7", "name": "NR0B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020641", "map_id": "ENSBTAT00000020641", "name": "NR0B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08E53", "map_id": "Q08E53", "name": "NR4A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004758", "map_id": "ENSBTAT00000004758", "name": "NR4A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1N8R7", "map_id": "A0A3Q1N8R7", "name": "THRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067712", "map_id": "ENSBTAT00000067712", "name": "THRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q08DY5", "map_id": "Q08DY5", "name": "NRBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024159", "map_id": "ENSBTAT00000024159", "name": "NRBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X7C1", "map_id": "G3X7C1", "name": "THRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000087040", "map_id": "ENSBTAT00000087040", "name": "THRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N3S3", "map_id": "F1N3S3", "name": "NR2F6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014791", "map_id": "ENSBTAT00000014791", "name": "NR2F6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBX3", "map_id": "F1MBX3", "name": "ESRRA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000036417", "map_id": "ENSBTAT00000036417", "name": "ESRRA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N712", "map_id": "F1N712", "name": "PGR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010545", "map_id": "ENSBTAT00000010545", "name": "PGR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M3W3", "map_id": "A0A3Q1M3W3", "name": "ESRRB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068282", "map_id": "ENSBTAT00000068282", "name": "ESRRB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWI2", "map_id": "F1MWI2", "name": "NR1D2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023994", "map_id": "ENSBTAT00000023994", "name": "NR1D2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0VC20", "map_id": "Q0VC20", "name": "RXRG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022350", "map_id": "ENSBTAT00000022350", "name": "RXRG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN19", "map_id": "F1MN19", "name": "NR3C1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077017", "map_id": "ENSBTAT00000077017", "name": "NR3C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LZU3", "map_id": "A0A3Q1LZU3", "name": "NR2C2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077868", "map_id": "ENSBTAT00000077868", "name": "NR2C2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O18971", "map_id": "O18971", "name": "PPARG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083374", "map_id": "ENSBTAT00000083374", "name": "PPARG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A2VDU4", "map_id": "A2VDU4", "name": "NR1I2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026059", "map_id": "ENSBTAT00000026059", "name": "NR1I2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BML7", "map_id": "E1BML7", "name": "NR0B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019772", "map_id": "ENSBTAT00000019772", "name": "NR0B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN68", "map_id": "F1MN68", "name": "NR2E1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018594", "map_id": "ENSBTAT00000018594", "name": "NR2E1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10046679", "map_id": "none", "name": "NR-NCOR CoRepressor Complex ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10054279", "map_id": "none", "name": "KRAB-ZNF / KAP Interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10053367", "map_id": "E1BJG5", "name": "TRIM28", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000008424", "map_id": "ENSBTAT00000008424", "name": "TRIM28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054275", "map_id": "none", "name": "KRAB-ZNF", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q17R08", "map_id": "Q17R08", "name": "ZNF45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080509", "map_id": "ENSBTAT00000080509", "name": "ZNF45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10054277", "map_id": "none", "name": "KRAB-ZNF / KAP Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BJG5", "map_id": "E1BJG5", "name": "TRIM28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065292", "map_id": "none", "name": "DDR1 binds collagen type I, II, III, IV, V, XI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065286", "map_id": "none", "name": "DDR1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BBP4", "map_id": "E1BBP4", "name": "DDR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046062", "map_id": "ENSBTAT00000046062", "name": "DDR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065288", "map_id": "none", "name": "Collagen type I, II, III, IV, V, XI fibrils", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10065290", "map_id": "none", "name": "DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10068042", "map_id": "none", "name": "Caspase-8 and FLIP(L) processing at DISC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10068038", "map_id": "none", "name": "DISC:p43/p41CASP8:p43 FLIP(L)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10068046", "map_id": "none", "name": "FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10068044", "map_id": "none", "name": "FASL:FAS Receptor Trimer:FADD:pro-Caspase-8:FLIP(L)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10067891", "map_id": "none", "name": "FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037981", "map_id": "none", "name": "TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BE56", "map_id": "E1BE56", "name": "TNFSF10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025281", "map_id": "ENSBTAT00000025281", "name": "TNFSF10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10067889", "map_id": "none", "name": "TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037985", "map_id": "none", "name": "TRAIL-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037983", "map_id": "none", "name": "TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10035396", "map_id": "none", "name": "FAS-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10035390", "map_id": "none", "name": "FASL:FAS receptor trimer:FADD:procaspase-8-dimer ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037991", "map_id": "none", "name": "TNF-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037987", "map_id": "none", "name": "TRADD:TRAF2:RIP1:FADD:CASP8(1-479)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10037989", "map_id": "none", "name": "TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10043049", "map_id": "none", "name": "Caspase-mediated cleavage of plectin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043047", "map_id": "A0A3Q1MRS3", "name": "PLEC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043045", "map_id": "A0A3Q1MRS3", "name": "PLEC", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044762", "map_id": "none", "name": "Caspase mediated cleavage of vimentin at IDVD (259)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043014", "map_id": "P48616", "name": "VIM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044758", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044760", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10043021", "map_id": "none", "name": "Caspase-mediated cleavage of vimentin at DSVD (85)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043018", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043016", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10043059", "map_id": "none", "name": "Caspase-mediated cleavage of GAS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043053", "map_id": "A8E4Q5", "name": "GAS2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000028855", "map_id": "ENSBTAT00000028855", "name": "GAS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043057", "map_id": "A8E4Q5", "name": "GAS2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043055", "map_id": "A8E4Q5", "name": "GAS2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044756", "map_id": "none", "name": "Caspase-mediated cleavage of vimentin at TNLD (429)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044743", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044745", "map_id": "P48616", "name": "VIM", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044923", "map_id": "none", "name": "Caspase-mediated cleavage of claspin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10040063", "map_id": "A0A3Q1LF69", "name": "CLSPN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044912", "map_id": "A0A3Q1LF69", "name": "CLSPN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044910", "map_id": "A0A3Q1LF69", "name": "CLSPN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044920", "map_id": "none", "name": "active caspase-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10044906", "map_id": "none", "name": "Caspase-mediated cleavage of MST3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044900", "map_id": "A2VE07", "name": "STK24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000075747", "map_id": "ENSBTAT00000075747", "name": "STK24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044902", "map_id": "A2VE07", "name": "STK24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044904", "map_id": "A2VE07", "name": "STK24", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090573", "map_id": "none", "name": "Caspase-7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10043039", "map_id": "none", "name": "Caspase-mediated cleavage of FADK 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10043037", "map_id": "A0A3Q1N508", "name": "PTK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10043035", "map_id": "A0A3Q1N508", "name": "PTK2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10044896", "map_id": "none", "name": "Caspase mediated cleavage of BAP31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10044887", "map_id": "Q5E9F1", "name": "BCAP31", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10044893", "map_id": "Q5E9F1", "name": "BCAP31", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10044891", "map_id": "Q5E9F1", "name": "BCAP31", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10044889", "map_id": "Q5E9F1", "name": "BCAP31", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10044867", "map_id": "none", "name": "active caspase-8 ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10044995", "map_id": "none", "name": "Cleavage of Satb1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10044989", "map_id": "A7MB41", "name": "SATB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000028199", "map_id": "ENSBTAT00000028199", "name": "SATB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10044993", "map_id": "A7MB41", "name": "SATB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10044991", "map_id": "A7MB41", "name": "SATB1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10044927", "map_id": "none", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10044925", "map_id": "A2VE07", "name": "STK24", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10044869", "map_id": "none", "name": "Translocation of active caspase-8 to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10037723", "map_id": "none", "name": "Phosphorylation of BIM by JNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037716", "map_id": "none", "name": "BIM sequestered to dynein (DLC1)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1NJ55", "map_id": "A0A3Q1NJ55", "name": "phospho-BCL2L11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037718", "map_id": "none", "name": "Dynein (DLC1) on microtubules", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037721", "map_id": "A0A3Q1NJ55", "name": "phospho-BCL2L11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10037727", "map_id": "none", "name": "Translocation of BIM to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037725", "map_id": "A0A3Q1NJ55", "name": "phospho-BCL2L11", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10037706", "map_id": "none", "name": "Translocation of BMF to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037695", "map_id": "Q05KI3", "name": "phospho-BMF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000077917", "map_id": "ENSBTAT00000077917", "name": "phospho-BMF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037704", "map_id": "Q05KI3", "name": "phospho-BMF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10037702", "map_id": "none", "name": "Phosphorylation of DLC2 by MAPK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037690", "map_id": "none", "name": "BMF sequestered to dynein (DLC2)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q3MHR3", "map_id": "Q3MHR3", "name": "DYNLL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000006190", "map_id": "ENSBTAT00000006190", "name": "DYNLL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q05KI3", "map_id": "Q05KI3", "name": "phospho-BMF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10037692", "map_id": "none", "name": "Dynein (DLC2) on microtubules", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10051181", "map_id": "none", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10037273", "map_id": "F6R2C4", "name": "BCL2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10051177", "map_id": "none", "name": "Bcl-2 interacting BH-3 only proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10051179", "map_id": "none", "name": "Bcl2:BH3-only protein complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10037277", "map_id": "none", "name": "Sequestration of tBID by BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "reaction_10051175", "map_id": "none", "name": "BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10051171", "map_id": "Q05KJ0", "name": "BCL2L1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000076163", "map_id": "ENSBTAT00000076163", "name": "BCL2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051167", "map_id": "none", "name": "Bcl-XL interacting BH3-only proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "A0A3Q1NFP6", "map_id": "A0A3Q1NFP6", "name": "PMAIP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051173", "map_id": "none", "name": "Bcl-XL:BH3-only protein complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q05KJ0", "map_id": "Q05KJ0", "name": "BCL2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037289", "map_id": "none", "name": "SMAC binds XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037283", "map_id": "none", "name": "XIAP:Caspase-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091191", "map_id": "none", "name": "SMAC (DIABLO) binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10037281", "map_id": "G3MWG5", "name": "XIAP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091197", "map_id": "none", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091193", "map_id": "none", "name": "SEPT4 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MXU1", "map_id": "A0A3Q1MXU1", "name": "SEPTIN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091195", "map_id": "none", "name": "SEPT4 dimer:XIAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10091188", "map_id": "none", "name": "XIAP binds CASP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10039930", "map_id": "none", "name": "NNMT transfers CH3 from AdoMet to PY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_175973", "map_id": "CHEBI:16227", "name": "PY", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_175979", "map_id": "CHEBI:15761", "name": "MP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10038238", "map_id": "none", "name": "TPMT transfers CH3 from AdoMet to 6MP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_158619", "map_id": "CHEBI:2208", "name": "6MP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158611", "map_id": "CHEBI:28279", "name": "6MMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10038235", "map_id": "Q17QQ2", "name": "TPMT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000025698", "map_id": "ENSBTAT00000025698", "name": "TPMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076898", "map_id": "none", "name": "AS3MT transfers CH3 from AdoMet to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5696224", "map_id": "CHEBI:14597", "name": "methylarsonite", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5696211", "map_id": "CHEBI:16223", "name": "dimethylarsinate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076895", "map_id": "A0A3Q1N140", "name": "AS3MT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000069974", "map_id": "ENSBTAT00000069974", "name": "AS3MT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071924", "map_id": "none", "name": "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071921", "map_id": "none", "name": "MAT2B:MAT2A:K+:2Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q29RI9", "map_id": "Q29RI9", "name": "MAT2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016399", "map_id": "ENSBTAT00000016399", "name": "MAT2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MZ37", "map_id": "A0A3Q1MZ37", "name": "MAT2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075325", "map_id": "ENSBTAT00000075325", "name": "MAT2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076900", "map_id": "none", "name": "AS3MT transfers CH3 from AdoMet to arsenite(3-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5696216", "map_id": "CHEBI:29866", "name": "arsenite(3-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5696214", "map_id": "CHEBI:16005", "name": "methylarsonate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035863", "map_id": "none", "name": "CYP1A2 S-demethylates 6MMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_76384", "map_id": "CHEBI:28279", "name": "6MMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_33153", "map_id": "CHEBI:2208", "name": "6MP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10076903", "map_id": "none", "name": "GSTO1 dimer reduces methylarsonate to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10039980", "map_id": "none", "name": "GSTO1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BJ08", "map_id": "E1BJ08", "name": "LOC785216", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017435", "map_id": "ENSBTAT00000017435", "name": "LOC785216", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10037800", "map_id": "none", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037763", "map_id": "A0A452DI66", "name": "F2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10037765", "map_id": "A0A452DI66", "name": "F2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10037795", "map_id": "none", "name": "Va:Xa", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037798", "map_id": "none", "name": "Va:Xa:Factor Xa inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037852", "map_id": "none", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037785", "map_id": "none", "name": "factor Xa", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037850", "map_id": "none", "name": "factor Xa:Factor Xa inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037948", "map_id": "none", "name": "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037921", "map_id": "none", "name": "thrombin:SERPINC1:SERPINC1 activators", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037945", "map_id": "none", "name": "thrombin:cleaved SERPINC1:SERPINC1 activators", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10037950", "map_id": "none", "name": "thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9693058", "map_id": "none", "name": "SERPINC1 activators", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10037923", "map_id": "none", "name": "activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037919", "map_id": "none", "name": "SERPINC1:SERPINC1 activators", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10071906", "map_id": "none", "name": "Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10037841", "map_id": "none", "name": "SERPINE2:GAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10037835", "map_id": "none", "name": "activated thrombin (factor IIa)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10090181", "map_id": "none", "name": "Factor Xa inhibitors binds Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9038743", "map_id": "none", "name": "Factor Xa inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10037845", "map_id": "none", "name": "factor V -> factor Va + factor V activation peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037817", "map_id": "F1N0I3", "name": "F5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10037813", "map_id": "none", "name": "factor Va", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10037819", "map_id": "F1N0I3", "name": "F5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10037815", "map_id": "none", "name": "factor Va + factor Xa -> Va:Xa complex (prothrombinase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10090183", "map_id": "none", "name": "Factor Xa inhibitors bind Va:Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10037927", "map_id": "none", "name": "SERPINC1 binds SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10037925", "map_id": "A0A3Q1NJR8", "name": "SERPINC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10055529", "map_id": "none", "name": "RAD51B:RAD51C binds single-stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_29868", "map_id": "CHEBI:9160", "name": "Single-stranded DNA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10055525", "map_id": "none", "name": "RAD51B:RAD51C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BE93", "map_id": "E1BE93", "name": "RAD51B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025252", "map_id": "ENSBTAT00000025252", "name": "RAD51B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055527", "map_id": "none", "name": "RAD51B:RAD51C:Single-stranded DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10055995", "map_id": "none", "name": "NFE2 binds the beta globin locus control region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055991", "map_id": "none", "name": "NF-E2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A7YY73", "map_id": "A7YY73", "name": "MAFF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028574", "map_id": "ENSBTAT00000028574", "name": "MAFF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5PJV0", "map_id": "A5PJV0", "name": "MAFG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000044", "map_id": "ENSBTAT00000000044", "name": "MAFG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q5EAD3", "map_id": "Q5EAD3", "name": "NFE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066479", "map_id": "ENSBTAT00000066479", "name": "NFE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1008228", "map_id": "none", "name": "Promotor region of beta-globin", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10055993", "map_id": "none", "name": "NF-E2:Promoter region of beta-globin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10055933", "map_id": "none", "name": "SH2B proteins bind JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10055926", "map_id": "none", "name": "SH2B family", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10055929", "map_id": "E1BCP6", "name": "phospho-JAK2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10055931", "map_id": "none", "name": "SH2B family:p-Y813-JAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10055870", "map_id": "none", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055855", "map_id": "F2Z4J7", "name": "CBX5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000008198", "map_id": "ENSBTAT00000008198", "name": "CBX5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055866", "map_id": "none", "name": "Histone H3 methylated at lysine-9", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10055868", "map_id": "none", "name": "HP1alpha:Histone H3 methylated at K9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F2Z4J7", "map_id": "F2Z4J7", "name": "CBX5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055649", "map_id": "none", "name": "RAD51B binds RAD51C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055519", "map_id": "E1BE93", "name": "RAD51B", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10055920", "map_id": "none", "name": "ZFPM proteins bind GATA proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10055890", "map_id": "none", "name": "ZFPM1, ZFPM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BBZ5", "map_id": "E1BBZ5", "name": "ZFPM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002161", "map_id": "ENSBTAT00000002161", "name": "ZFPM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055916", "map_id": "none", "name": "GATA proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MC01", "map_id": "A0A3Q1MC01", "name": "GATA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066877", "map_id": "ENSBTAT00000066877", "name": "GATA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N1M2", "map_id": "F1N1M2", "name": "GATA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007537", "map_id": "ENSBTAT00000007537", "name": "GATA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGB0", "map_id": "A0A3Q1MGB0", "name": "GATA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071546", "map_id": "ENSBTAT00000071546", "name": "GATA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N551", "map_id": "F1N551", "name": "GATA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007134", "map_id": "ENSBTAT00000007134", "name": "GATA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZJ5", "map_id": "Q3SZJ5", "name": "GATA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027184", "map_id": "ENSBTAT00000027184", "name": "GATA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10055918", "map_id": "none", "name": "ZFPM proteins:GATA proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10056002", "map_id": "none", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10055999", "map_id": "P08760", "name": "AK3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000022789", "map_id": "ENSBTAT00000022789", "name": "AK3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10055847", "map_id": "none", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10055843", "map_id": "none", "name": "Mitofusins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10055845", "map_id": "none", "name": "Mitofusin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10085753", "map_id": "none", "name": "PSGs bind proteoglycans and TGF-beta1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10085749", "map_id": "none", "name": "PSGs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LX90", "map_id": "A0A3Q1LX90", "name": "PSG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085051", "map_id": "ENSBTAT00000085051", "name": "PSG3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M7Z2", "map_id": "A0A3Q1M7Z2", "name": "LOC112441502", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081146", "map_id": "ENSBTAT00000081146", "name": "LOC112441502", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MS45", "map_id": "A0A3Q1MS45", "name": "PSG3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10085701", "map_id": "none", "name": "Proteoglycans,TGFB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10085751", "map_id": "none", "name": "PSGs:Proteoglycan,TGFB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043323", "map_id": "none", "name": "JAM2 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043319", "map_id": "A4IFI9", "name": "JAM2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000080737", "map_id": "ENSBTAT00000080737", "name": "JAM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043321", "map_id": "none", "name": "JAM2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A4IFI9", "map_id": "A4IFI9", "name": "JAM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043355", "map_id": "none", "name": "Heterodimerization of CEACAMs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043351", "map_id": "A0A3Q1MQ27", "name": "CEACAM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10043353", "map_id": "none", "name": "CEACAM heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043375", "map_id": "none", "name": "CD48 binds CD244", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043367", "map_id": "Q2KHZ6", "name": "CD48", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000014924", "map_id": "ENSBTAT00000014924", "name": "CD48", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043371", "map_id": "A0A3Q1LFU5", "name": "CD244", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000084280", "map_id": "ENSBTAT00000084280", "name": "CD244", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043373", "map_id": "none", "name": "CD48:CD244", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LFU5", "map_id": "A0A3Q1LFU5", "name": "CD244", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KHZ6", "map_id": "Q2KHZ6", "name": "CD48", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044024", "map_id": "none", "name": "Interaction of PECAM-1 and PLC gamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044022", "map_id": "none", "name": "PECAM-1:PLC gamma1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044030", "map_id": "none", "name": "Trans-homophilic interaction of PECAM-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10044028", "map_id": "none", "name": "PECAM1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044034", "map_id": "none", "name": "Interaction of PECAM-1 and SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044032", "map_id": "none", "name": "PECAM-1:SHIP1 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10044039", "map_id": "none", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044036", "map_id": "none", "name": "p-Y663,Y686-PECAM1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043393", "map_id": "none", "name": "P-selectin binds P-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043379", "map_id": "F1MS77", "name": "SELPLG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000029578", "map_id": "ENSBTAT00000029578", "name": "SELPLG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043389", "map_id": "none", "name": "Selectins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P98107", "map_id": "P98107", "name": "SELE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009612", "map_id": "ENSBTAT00000009612", "name": "SELE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2KJA9", "map_id": "Q2KJA9", "name": "ESAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000057091", "map_id": "ENSBTAT00000057091", "name": "ESAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043391", "map_id": "none", "name": "Selectins:2xSELPG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MS77", "map_id": "F1MS77", "name": "SELPLG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043363", "map_id": "none", "name": "JAM2 binds JAM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043359", "map_id": "A0A3Q1M4F2", "name": "JAM3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000081263", "map_id": "ENSBTAT00000081263", "name": "JAM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043361", "map_id": "none", "name": "JAM2:JAM3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1M4F2", "map_id": "A0A3Q1M4F2", "name": "JAM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043347", "map_id": "none", "name": "CD58 binds CD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043343", "map_id": "F6PZJ9", "name": "CD58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10043339", "map_id": "Q148M9", "name": "CD2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000022936", "map_id": "ENSBTAT00000022936", "name": "CD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043345", "map_id": "none", "name": "CD58:CD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q148M9", "map_id": "Q148M9", "name": "CD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10043397", "map_id": "none", "name": "JAM3 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043395", "map_id": "none", "name": "JAM3 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10043335", "map_id": "none", "name": "CD84 homodimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10043331", "map_id": "F1N7U9", "name": "CD84", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000053223", "map_id": "ENSBTAT00000053223", "name": "CD84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043333", "map_id": "none", "name": "CD84 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N7U9", "map_id": "F1N7U9", "name": "CD84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10066263", "map_id": "none", "name": "E-selectin binds E-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10066259", "map_id": "none", "name": "SELE ligands", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LL67", "map_id": "A0A3Q1LL67", "name": "GLG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083484", "map_id": "ENSBTAT00000083484", "name": "GLG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQP5", "map_id": "A6QQP5", "name": "SPN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037368", "map_id": "ENSBTAT00000037368", "name": "SPN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10043387", "map_id": "P98107", "name": "SELE", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10066261", "map_id": "none", "name": "2xSELE ligands:SELE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10038329", "map_id": "none", "name": "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038260", "map_id": "none", "name": "Plasmin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10038324", "map_id": "P28800", "name": "SERPINF2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038326", "map_id": "none", "name": "alpha-2-antiplasmin:plasmin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038285", "map_id": "none", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038272", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10038267", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10038283", "map_id": "none", "name": "ANXA2:S100A10 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane", "complex": "true" }, { "id": "P60902", "map_id": "P60902", "name": "S100A10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020150", "map_id": "ENSBTAT00000020150", "name": "S100A10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038303", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038296", "map_id": "A0A452DIJ9", "name": "SERPINE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038298", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10038300", "map_id": "none", "name": "SERPINE1-like proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038270", "map_id": "none", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038248", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038288", "map_id": "none", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038252", "map_id": "E1B726", "name": "PLG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038254", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038307", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10038305", "map_id": "none", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10038290", "map_id": "none", "name": "crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_157771", "map_id": "none", "name": "fibrin multimer, crosslinked", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10038265", "map_id": "A0A452DIF6", "name": "PLAT", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10038292", "map_id": "none", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10038263", "map_id": "none", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10057598", "map_id": "none", "name": "Association of Acrosin Heavy and Light Chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10057594", "map_id": "G5E5C6", "name": "ACR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000013434", "map_id": "ENSBTAT00000013434", "name": "ACR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10057592", "map_id": "G5E5C6", "name": "ACR", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10057596", "map_id": "none", "name": "Acrosin Heavy:light chain", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "G5E5C6", "map_id": "G5E5C6", "name": "ACR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057605", "map_id": "none", "name": "Acrosin Cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10057602", "map_id": "G5E5C6", "name": "ACR", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10091211", "map_id": "none", "name": "NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091207", "map_id": "none", "name": "Gh-Telomeric DNA:Shelterin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10091201", "map_id": "A0A3Q1M1H9", "name": "NEIL3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000084434", "map_id": "ENSBTAT00000084434", "name": "NEIL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10091209", "map_id": "none", "name": "NEIL3:Gh-Telomeric DNA:Shelterin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1M1H9", "map_id": "A0A3Q1M1H9", "name": "NEIL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091566", "map_id": "none", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091562", "map_id": "F1MPV2", "name": "OGG1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10091564", "map_id": "F1MPV2", "name": "OGG1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10035854", "map_id": "none", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_76050", "map_id": "none", "name": "DNA with RNA Polymerase III Type 1 Closed Promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035850", "map_id": "F1MUY9", "name": "GTF3A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000016732", "map_id": "ENSBTAT00000016732", "name": "GTF3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035852", "map_id": "none", "name": "TFIIIA:Type 1 Promoter complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MUY9", "map_id": "F1MUY9", "name": "GTF3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036760", "map_id": "none", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036755", "map_id": "none", "name": "OGG1:(8oxoG:Cyt)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110242", "map_id": "CHEBI:44605", "name": "8oxoG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10091240", "map_id": "none", "name": "NEIL3 cleaves spiroiminodihydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091237", "map_id": "none", "name": "NEIL3:Sp-DNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_9629439", "map_id": "CHEBI:142623", "name": "Sp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10091230", "map_id": "none", "name": "NEIL3:AP-DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036782", "map_id": "none", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036777", "map_id": "none", "name": "MUTYH:(8oxoG:Ade)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1N4K4", "map_id": "F1N4K4", "name": "MUTYH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014928", "map_id": "ENSBTAT00000014928", "name": "MUTYH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036779", "map_id": "none", "name": "MUTYH:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036798", "map_id": "none", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036795", "map_id": "none", "name": "MPG:EtAD-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MKN2", "map_id": "F1MKN2", "name": "MPG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000037548", "map_id": "ENSBTAT00000037548", "name": "MPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036788", "map_id": "none", "name": "MPG:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110249", "map_id": "CHEBI:29146", "name": "EtAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10091233", "map_id": "none", "name": "NEIL3 cleaves 5-guanidinohydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091226", "map_id": "none", "name": "NEIL3:Gh-DNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_9629218", "map_id": "CHEBI:142614", "name": "Gh", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10036805", "map_id": "none", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036802", "map_id": "none", "name": "MPG:Hyp-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036791", "map_id": "none", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036786", "map_id": "none", "name": "MPG:MADE-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30947", "map_id": "CHEBI:38635", "name": "MADE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10091222", "map_id": "none", "name": "NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10091219", "map_id": "none", "name": "NEIL3:AP-Telomeric DNA:Shelterin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10072876", "map_id": "none", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072868", "map_id": "E1BKF4", "name": "USP43", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000000131", "map_id": "ENSBTAT00000000131", "name": "USP43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072872", "map_id": "none", "name": "ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N5S1", "map_id": "A0A3Q1N5S1", "name": "RFC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076791", "map_id": "ENSBTAT00000076791", "name": "RFC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072874", "map_id": "none", "name": "USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BKF4", "map_id": "E1BKF4", "name": "USP43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10072883", "map_id": "none", "name": "USP43 deISGylates ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10072880", "map_id": "O02741", "name": "ISG15", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10072878", "map_id": "none", "name": "PCNA:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073302", "map_id": "none", "name": "KIAA0101 double monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073294", "map_id": "Q5E9B2", "name": "PCLAF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000054209", "map_id": "ENSBTAT00000054209", "name": "PCLAF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073300", "map_id": "none", "name": "MonoUb:K15,K24-KIAA0101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q5E9B2", "map_id": "Q5E9B2", "name": "PCLAF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044547", "map_id": "none", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_171149", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_194276", "map_id": "CHEBI:16110", "name": "phosphatidylcholines", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_194236", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171076", "map_id": "CHEBI:17002", "name": "CHEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10044544", "map_id": "Q2KIW4", "name": "LCAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "ENSBTAT00000024018", "map_id": "ENSBTAT00000024018", "name": "LCAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088982", "map_id": "none", "name": "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_174602", "map_id": "CHEBI:15904", "name": "LCFAs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10088979", "map_id": "none", "name": "LIPG dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1LR40", "map_id": "A0A3Q1LR40", "name": "LIPG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075023", "map_id": "ENSBTAT00000075023", "name": "LIPG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10084509", "map_id": "none", "name": "GPIHBP1 binds HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10077472", "map_id": "A0A3Q1MPP4", "name": "GPIHBP1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000071232", "map_id": "ENSBTAT00000071232", "name": "GPIHBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077480", "map_id": "none", "name": "HSPG:LPL dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_1678620", "map_id": "CHEBI:24499", "name": "HSPG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P11151", "map_id": "P11151", "name": "LPL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017086", "map_id": "ENSBTAT00000017086", "name": "LPL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077482", "map_id": "none", "name": "GPIHBP1:HSPG:LPL dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MPP4", "map_id": "A0A3Q1MPP4", "name": "GPIHBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077487", "map_id": "none", "name": "PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10077476", "map_id": "P11151", "name": "LPL", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10077484", "map_id": "A0A3Q1MCD7", "name": "PCSK5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10077489", "map_id": "none", "name": "HSPG binds LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10077478", "map_id": "none", "name": "LPL dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10077593", "map_id": "none", "name": "FANCM binds FAAP24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077506", "map_id": "A0A3Q1MT39", "name": "FANCM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000071085", "map_id": "ENSBTAT00000071085", "name": "phospho-FANCM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077502", "map_id": "Q2KHY5", "name": "FAAP24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000065656", "map_id": "ENSBTAT00000065656", "name": "FAAP24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077508", "map_id": "none", "name": "FANCM:FAAP24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q2KHY5", "map_id": "Q2KHY5", "name": "FAAP24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MT39", "map_id": "A0A3Q1MT39", "name": "phospho-FANCM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077625", "map_id": "none", "name": "DNA nucleases bind monoubiquitinated ID2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077619", "map_id": "none", "name": "DCLRE1A,DCLRE1B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BN11", "map_id": "E1BN11", "name": "DCLRE1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026896", "map_id": "ENSBTAT00000026896", "name": "DCLRE1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077582", "map_id": "none", "name": "MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BE83", "map_id": "E1BE83", "name": "phospho-FANCD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013299", "map_id": "ENSBTAT00000013299", "name": "phospho-FANCD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIP1", "map_id": "A0A452DIP1", "name": "FAAP20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018787", "map_id": "ENSBTAT00000018787", "name": "FAAP20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MWV7", "map_id": "F1MWV7", "name": "FANCF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009509", "map_id": "ENSBTAT00000009509", "name": "FANCF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B6X8", "map_id": "E1B6X8", "name": "FANCA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002478", "map_id": "ENSBTAT00000002478", "name": "FANCA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QQ29", "map_id": "A6QQ29", "name": "FANCG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056722", "map_id": "ENSBTAT00000056722", "name": "FANCG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3X787", "map_id": "G3X787", "name": "FANCB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082853", "map_id": "ENSBTAT00000082853", "name": "FANCB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2TBN8", "map_id": "Q2TBN8", "name": "FANCL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007713", "map_id": "ENSBTAT00000007713", "name": "FANCL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077609", "map_id": "A0A3Q1MJE2", "name": "FAN1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000085708", "map_id": "ENSBTAT00000085708", "name": "FAN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077623", "map_id": "none", "name": "MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MJE2", "map_id": "A0A3Q1MJE2", "name": "FAN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077591", "map_id": "none", "name": "Monoubiquitination of FANCD2:FANCI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10077569", "map_id": "none", "name": "p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MQ26", "map_id": "A0A3Q1MQ26", "name": "UBE2T", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068467", "map_id": "ENSBTAT00000068467", "name": "UBE2T", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10077588", "map_id": "none", "name": "MonoUb:K91,K182-UBE2T", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10035372", "map_id": "none", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73917", "map_id": "CHEBI:15467", "name": "HMG CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10035369", "map_id": "Q2KIE6", "name": "HMGCS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000005088", "map_id": "ENSBTAT00000005088", "name": "HMGCS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035363", "map_id": "none", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10049883", "map_id": "none", "name": "PARVA associates with Paxillin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049879", "map_id": "A0A3Q1LMM6", "name": "PARVA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000081787", "map_id": "ENSBTAT00000081787", "name": "PARVA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049875", "map_id": "F1MFD1", "name": "PXN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10049881", "map_id": "none", "name": "PARVA:Paxillin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1LMM6", "map_id": "A0A3Q1LMM6", "name": "PARVA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049312", "map_id": "none", "name": "PARVB/Affixin interacts with alpha PIX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049308", "map_id": "A0A3Q1M7B6", "name": "PARVB", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000084501", "map_id": "ENSBTAT00000084501", "name": "PARVB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049310", "map_id": "none", "name": "ParvB/Affixin:Alpha-Pix", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1M7B6", "map_id": "A0A3Q1M7B6", "name": "PARVB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049891", "map_id": "none", "name": "Association of PARVA with TESK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049887", "map_id": "A0A3Q1MET9", "name": "TESK1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000082961", "map_id": "ENSBTAT00000082961", "name": "TESK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10049889", "map_id": "none", "name": "PARVA:TESK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MET9", "map_id": "A0A3Q1MET9", "name": "TESK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038942", "map_id": "none", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035753", "map_id": "Q95JH2", "name": "AGPAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10036844", "map_id": "none", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036840", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036809", "map_id": "A0A3Q1MPW7", "name": "REV1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000066497", "map_id": "ENSBTAT00000066497", "name": "REV1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036842", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MPW7", "map_id": "A0A3Q1MPW7", "name": "REV1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036853", "map_id": "none", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036850", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073275", "map_id": "none", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073270", "map_id": "none", "name": "NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "F1MZ79", "map_id": "F1MZ79", "name": "POLH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007900", "map_id": "ENSBTAT00000007900", "name": "POLH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A5D979", "map_id": "A5D979", "name": "SPRTN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000008030", "map_id": "ENSBTAT00000008030", "name": "SPRTN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N7U2", "map_id": "F1N7U2", "name": "NPLOC4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000042613", "map_id": "ENSBTAT00000042613", "name": "NPLOC4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073272", "map_id": "none", "name": "NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036857", "map_id": "F1MZ79", "name": "POLH", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10073290", "map_id": "none", "name": "RCHY1 monoubiquitinates POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073277", "map_id": "none", "name": "POLH:RCHY1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A4IFE2", "map_id": "A4IFE2", "name": "RCHY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009461", "map_id": "ENSBTAT00000009461", "name": "RCHY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10073287", "map_id": "none", "name": "MonoUb:K682,K686,K694,K709-POLH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036867", "map_id": "A4IFE2", "name": "RCHY1", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10036879", "map_id": "none", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036863", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10036876", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073279", "map_id": "none", "name": "RCHY1 binds POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10036869", "map_id": "none", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036861", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10036886", "map_id": "none", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10036883", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10073254", "map_id": "none", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10073250", "map_id": "A5D979", "name": "SPRTN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10073252", "map_id": "none", "name": "SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10090392", "map_id": "none", "name": "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090394", "map_id": "none", "name": "ALOX15 oxidises DHA to 17(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090462", "map_id": "none", "name": "ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024873", "map_id": "CHEBI:140225", "name": "16S,17S-epoxy-DHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090384", "map_id": "none", "name": "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090464", "map_id": "none", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090458", "map_id": "none", "name": "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024764", "map_id": "CHEBI:81564", "name": "RvD1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024799", "map_id": "none", "name": "17(S)-oxo-RvD1, 8-oxo-17(S)-RvD1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:132797", "map_id": "CHEBI:132797", "name": "CHEBI:132797", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:132800", "map_id": "CHEBI:132800", "name": "CHEBI:132800", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064497", "map_id": "none", "name": "HPGD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q309F3", "map_id": "Q309F3", "name": "HPGD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027024", "map_id": "ENSBTAT00000027024", "name": "HPGD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10090390", "map_id": "none", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024815", "map_id": "CHEBI:138640", "name": "17(S)-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10090371", "map_id": "Q9N2J2", "name": "GPX4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090388", "map_id": "none", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024463", "map_id": "CHEBI:91137", "name": "17(R)-HDHA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10062377", "map_id": "none", "name": "Removal of fibrillar collagen C-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10062335", "map_id": "none", "name": "Fibrillar procollagens -N", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10058697", "map_id": "none", "name": "Tropocollagens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10062368", "map_id": "none", "name": "Procollagen C-proteinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10062375", "map_id": "none", "name": "PCOLCEs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q2HJB6", "map_id": "Q2HJB6", "name": "PCOLCE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027347", "map_id": "ENSBTAT00000027347", "name": "PCOLCE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MKP1", "map_id": "F1MKP1", "name": "PCOLCE2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021330", "map_id": "ENSBTAT00000021330", "name": "PCOLCE2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061787", "map_id": "none", "name": "Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10061734", "map_id": "none", "name": "Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:29073", "map_id": "CHEBI:29073", "name": "CHEBI:29073", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QLY3", "map_id": "A6QLY3", "name": "P3H2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027999", "map_id": "ENSBTAT00000027999", "name": "P3H2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1650779", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_1650769", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10061784", "map_id": "none", "name": "Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10060187", "map_id": "none", "name": "Dimerization of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060185", "map_id": "none", "name": "Collagen type VI dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087626", "map_id": "none", "name": "COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10061921", "map_id": "none", "name": "Lysyl hydroxylated collagen propeptides", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10061791", "map_id": "F1N0V8", "name": "COLGALT2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000050322", "map_id": "ENSBTAT00000050322", "name": "COLGALT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10061923", "map_id": "none", "name": "COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1N0V8", "map_id": "F1N0V8", "name": "COLGALT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10062058", "map_id": "none", "name": "Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_1981137", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10062055", "map_id": "none", "name": "COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10087628", "map_id": "none", "name": "COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062053", "map_id": "none", "name": "Galactosyl-hydroxylysyl collagen propeptides", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10060191", "map_id": "none", "name": "Tetramerization of procollagen VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10060189", "map_id": "none", "name": "Collagen type VI tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "reaction_10064337", "map_id": "none", "name": "Secretion of transmembrane collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10062852", "map_id": "none", "name": "Transmembrane collagens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_10064335", "map_id": "none", "name": "Transmembrane collagens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10062352", "map_id": "none", "name": "Removal of fibrillar collagen N-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10062205", "map_id": "none", "name": "Fibrillar procollagens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10062349", "map_id": "none", "name": "Procollagen N-proteinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BC50", "map_id": "E1BC50", "name": "ADAMTS3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061447", "map_id": "ENSBTAT00000061447", "name": "ADAMTS3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BFV4", "map_id": "E1BFV4", "name": "ADAMTS14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028224", "map_id": "ENSBTAT00000028224", "name": "ADAMTS14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10063799", "map_id": "none", "name": "Secretion of collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10063637", "map_id": "none", "name": "Collagens and tropocollagens:Serpin H1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "Q2KJH6", "map_id": "Q2KJH6", "name": "SERPINH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083385", "map_id": "ENSBTAT00000083385", "name": "SERPINH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10063797", "map_id": "none", "name": "Collagens and tropocollagens", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10062846", "map_id": "Q2KJH6", "name": "SERPINH1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10064491", "map_id": "none", "name": "ALOX12 oxidises LTA4 to LXA4/B4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9032038", "map_id": "CHEBI:15651", "name": "LTA4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2161856", "map_id": "none", "name": "LXA4/B4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:6499", "map_id": "CHEBI:6499", "name": "CHEBI:6499", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2161759", "map_id": "CHEBI:6498", "name": "LXA4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10064500", "map_id": "none", "name": "LXA4 is oxidised to 15k-LXA4 by HPGD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2142761", "map_id": "CHEBI:63992", "name": "15k-LXA4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065691", "map_id": "none", "name": "BGN binds Collagen types I, VI, (IX)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10062553", "map_id": "P21809", "name": "BGN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10065689", "map_id": "none", "name": "BGN:Collagen types I, VI, (IX)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10065300", "map_id": "none", "name": "DCN binds collagen I, II, III, VI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065296", "map_id": "none", "name": "Collagen type I, II, III, VI fibrils", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10065298", "map_id": "none", "name": "DCN:Collagen type I, II, III, VI fibrils", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10064953", "map_id": "none", "name": "Formation of collagen fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10058703", "map_id": "none", "name": "Collagen fibrils", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10064951", "map_id": "none", "name": "Collagen fibres", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10064959", "map_id": "none", "name": "Formation of collagen networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064955", "map_id": "none", "name": "Network forming tropocollagens", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10064957", "map_id": "none", "name": "Collagen networks", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10058705", "map_id": "none", "name": "Formation of collagen fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10065929", "map_id": "none", "name": "Collagen type IV sulfilimine cross-linking by peroxidasin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065920", "map_id": "none", "name": "Sulfilimine-containing collagen type IV alpha1.alpha2.alpha5.alpha6 network", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10065926", "map_id": "none", "name": "PXDN:Br-", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:15858", "map_id": "CHEBI:15858", "name": "CHEBI:15858", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMN6", "map_id": "A0A3Q1LMN6", "name": "PXDN", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073028", "map_id": "ENSBTAT00000073028", "name": "PXDN", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035464", "map_id": "none", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30064", "map_id": "CHEBI:17712", "name": "XAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035461", "map_id": "none", "name": "GDA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MLX9", "map_id": "F1MLX9", "name": "GDA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015339", "map_id": "ENSBTAT00000015339", "name": "GDA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10088571", "map_id": "none", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109327", "map_id": "CHEBI:16192", "name": "2'-deoxyguanosine 5'-monophosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_8953344", "map_id": "CHEBI:19569", "name": "2DORP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10088568", "map_id": "E1BM28", "name": "DNPH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026530", "map_id": "ENSBTAT00000026530", "name": "DNPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035453", "map_id": "none", "name": "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500172", "map_id": "none", "name": "Ino, dI", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28997", "map_id": "CHEBI:28997", "name": "CHEBI:28997", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113599", "map_id": "CHEBI:17368", "name": "Hyp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_500244", "map_id": "none", "name": "R1P, dRibP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28542", "map_id": "CHEBI:28542", "name": "CHEBI:28542", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035450", "map_id": "none", "name": "NP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10036207", "map_id": "none", "name": "NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_500101", "map_id": "none", "name": "AMP, dAMP, GMP, IMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_500104", "map_id": "none", "name": "Ade-Rib, dA, Gua-Rib, Ino", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10035455", "map_id": "none", "name": "(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500245", "map_id": "none", "name": "G, dG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17172", "map_id": "CHEBI:17172", "name": "CHEBI:17172", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036238", "map_id": "none", "name": "AMP + H2O => adenosine + orthophosphate [NT5C1B]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036235", "map_id": "F1ML59", "name": "NT5C1B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000006950", "map_id": "ENSBTAT00000006950", "name": "NT5C1B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036256", "map_id": "none", "name": "(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500120", "map_id": "none", "name": "(d)GMP, (d)IMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500118", "map_id": "none", "name": "Gu-Rib, dG, Ino, dI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036253", "map_id": "none", "name": "NT5C dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "G3X6X2", "map_id": "G3X6X2", "name": "NT5C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015317", "map_id": "ENSBTAT00000015317", "name": "NT5C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036231", "map_id": "none", "name": "(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500125", "map_id": "none", "name": "(d)AMP, (d)GMP, (d)IMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500124", "map_id": "none", "name": "(d)A, (d)G, (d)I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036226", "map_id": "none", "name": "NT5C1A tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BF39", "map_id": "E1BF39", "name": "NT5C1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003884", "map_id": "ENSBTAT00000003884", "name": "NT5C1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10053044", "map_id": "none", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10053039", "map_id": "none", "name": "SMG1:UPF1:EJC:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q0VC92", "map_id": "Q0VC92", "name": "MAGOHB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025615", "map_id": "ENSBTAT00000025615", "name": "MAGOHB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHY5", "map_id": "A0A452DHY5", "name": "MAGOH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004528", "map_id": "ENSBTAT00000004528", "name": "MAGOH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRF2", "map_id": "A0A3Q1LRF2", "name": "UPF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000075557", "map_id": "ENSBTAT00000075557", "name": "UPF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QR16", "map_id": "A6QR16", "name": "RNPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078713", "map_id": "ENSBTAT00000078713", "name": "RNPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MBL6", "map_id": "F1MBL6", "name": "SMG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027632", "map_id": "ENSBTAT00000027632", "name": "SMG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10053041", "map_id": "none", "name": "SMG1:Phosphorylated UPF1:EJC:Translated mRNP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10090377", "map_id": "none", "name": "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9022921", "map_id": "none", "name": "18(S)-HpEPE, 18(R)-HpEPE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_9023653", "map_id": "CHEBI:138565", "name": "18(R)-HpEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9020583", "map_id": "CHEBI:138387", "name": "18(S)-HpEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090440", "map_id": "none", "name": "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023963", "map_id": "CHEBI:131617", "name": "18-oxo-RvE1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090396", "map_id": "none", "name": "ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9020474", "map_id": "CHEBI:132801", "name": "18(S)-HEPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9022679", "map_id": "CHEBI:138477", "name": "18(S)-RvE3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090374", "map_id": "none", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10090379", "map_id": "none", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023651", "map_id": "CHEBI:81563", "name": "18(R)-HEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10090382", "map_id": "none", "name": "ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023644", "map_id": "CHEBI:138542", "name": "(18R)-resolvin E3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10065866", "map_id": "none", "name": "CatSper Channel Mediated Calcium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065861", "map_id": "none", "name": "Activated CatSper Channel", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1B9V5", "map_id": "E1B9V5", "name": "CATSPERB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024903", "map_id": "ENSBTAT00000024903", "name": "CATSPERB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHU9", "map_id": "A0A452DHU9", "name": "CATSPERD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002352", "map_id": "ENSBTAT00000002352", "name": "CATSPERD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MED0", "map_id": "F1MED0", "name": "CATSPERG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000056871", "map_id": "ENSBTAT00000056871", "name": "CATSPERG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BGU6", "map_id": "E1BGU6", "name": "CATSPER2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000045580", "map_id": "ENSBTAT00000045580", "name": "CATSPER2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N390", "map_id": "F1N390", "name": "CATSPER3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019622", "map_id": "ENSBTAT00000019622", "name": "CATSPER3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3MZP0", "map_id": "G3MZP0", "name": "CATSPER4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000063395", "map_id": "ENSBTAT00000063395", "name": "CATSPER4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N4E7", "map_id": "F1N4E7", "name": "CATSPER1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019586", "map_id": "ENSBTAT00000019586", "name": "CATSPER1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065884", "map_id": "none", "name": "Hv1 Mediated H+ Permeability", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1132304", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_459", "compartment_display": "cytoplasm", "complex": "false" }, { "id": "species_10065881", "map_id": "none", "name": "HV1 Channel", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10065886", "map_id": "none", "name": "Progesterone Activation Of CatSper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065863", "map_id": "none", "name": "CatSper Channel", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_1449667", "map_id": "CHEBI:17026", "name": "P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10065875", "map_id": "none", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065872", "map_id": "none", "name": "Slo3 Channel", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3S5ZP59", "map_id": "A0A3S5ZP59", "name": "KCNU1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038859", "map_id": "ENSBTAT00000038859", "name": "KCNU1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076856", "map_id": "none", "name": "AOC1 deaminates Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5696128", "map_id": "CHEBI:27398", "name": "I4AH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076853", "map_id": "none", "name": "AOC1 dimer:2xCu2+:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077496", "map_id": "none", "name": "BPHL hydrolyses VACV to ACV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6784964", "map_id": "CHEBI:35854", "name": "VACV", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077493", "map_id": "F1MFG7", "name": "BPHL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "ENSBTAT00000008368", "map_id": "ENSBTAT00000008368", "name": "BPHL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076475", "map_id": "none", "name": "EPHX1 hydrates BaP4,5O to BaP4,5-DHD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5694080", "map_id": "CHEBI:34560", "name": "BaP4,5O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5694091", "map_id": "CHEBI:81621", "name": "BaP4,5-DHD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076472", "map_id": "Q3ZCJ6", "name": "EPHX1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000083641", "map_id": "ENSBTAT00000083641", "name": "EPHX1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076863", "map_id": "none", "name": "AOC2 deaminates TYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5696181", "map_id": "CHEBI:15760", "name": "TYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5696178", "map_id": "CHEBI:15621", "name": "4HPAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076860", "map_id": "E1BC09", "name": "AOC2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000042833", "map_id": "ENSBTAT00000042833", "name": "AOC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076884", "map_id": "none", "name": "AOC3 deaminates BZAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5696148", "map_id": "CHEBI:40538", "name": "BZAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5696154", "map_id": "CHEBI:17169", "name": "BZAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10076881", "map_id": "none", "name": "AOC3 dimer:2xCu2+:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9TTK6", "map_id": "Q9TTK6", "name": "AOC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081083", "map_id": "ENSBTAT00000081083", "name": "AOC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DHX8", "map_id": "A0A452DHX8", "name": "LOC100138645", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001383", "map_id": "ENSBTAT00000001383", "name": "LOC100138645", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q29437", "map_id": "Q29437", "name": "AOC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076375", "map_id": "none", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_5693702", "map_id": "CHEBI:27958", "name": "COCN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5693711", "map_id": "CHEBI:17790", "name": "MeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5693712", "map_id": "CHEBI:41001", "name": "BEG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10076372", "map_id": "none", "name": "CES1 trimer, CES2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "F1MU22", "map_id": "F1MU22", "name": "CES2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000032343", "map_id": "ENSBTAT00000032343", "name": "CES2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086550", "map_id": "none", "name": "CBR3 reduces DOX to DOXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8937424", "map_id": "CHEBI:28748", "name": "DOX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8937418", "map_id": "CHEBI:133817", "name": "DOXOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086547", "map_id": "Q0VC97", "name": "CBR3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000024873", "map_id": "ENSBTAT00000024873", "name": "CBR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044524", "map_id": "none", "name": "FMO1:FAD N-oxidises TAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_217269", "map_id": "CHEBI:63825", "name": "TAMO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044521", "map_id": "none", "name": "FMO1:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1M207", "map_id": "A0A3Q1M207", "name": "FMO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079411", "map_id": "ENSBTAT00000079411", "name": "FMO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10044533", "map_id": "none", "name": "FMO2:FAD:Mg2+ S-oxidises MTZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17960", "compartment_display": "smooth endoplasmic reticulum" }, { "id": "species_217315", "map_id": "CHEBI:50673", "name": "MTZ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_217320", "map_id": "CHEBI:63828", "name": "MTZ-SOX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10044530", "map_id": "none", "name": "FMO2:FAD:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "G5E540", "map_id": "G5E540", "name": "FMO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003873", "map_id": "ENSBTAT00000003873", "name": "FMO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034175", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10034206", "map_id": "none", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30203", "map_id": "CHEBI:16236", "name": "EtOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034203", "map_id": "none", "name": "alcohol dehydrogenase complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BBW9", "map_id": "E1BBW9", "name": "ADH7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020879", "map_id": "ENSBTAT00000020879", "name": "ADH7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MZN9", "map_id": "F1MZN9", "name": "ADH6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009191", "map_id": "ENSBTAT00000009191", "name": "ADH6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050160", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113539", "map_id": "CHEBI:30089", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10050157", "map_id": "A0A3Q1MS98", "name": "ACSS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000086374", "map_id": "ENSBTAT00000086374", "name": "ACSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076144", "map_id": "none", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692221", "map_id": "CHEBI:48926", "name": "S-HMGSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692249", "map_id": "CHEBI:16225", "name": "S-FGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076141", "map_id": "none", "name": "ADH5:2xZn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3ZC42", "map_id": "Q3ZC42", "name": "ADH5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021304", "map_id": "ENSBTAT00000021304", "name": "ADH5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034215", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10034231", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034228", "map_id": "A0A3Q1MB37", "name": "ACSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000078990", "map_id": "ENSBTAT00000078990", "name": "ACSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075404", "map_id": "none", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5689006", "map_id": "CHEBI:8050", "name": "PHEN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5689001", "map_id": "CHEBI:40574", "name": "acetyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5688995", "map_id": "CHEBI:85505", "name": "4-ethoxyaniline", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10075401", "map_id": "G3X6X4", "name": "AADAC", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "ENSBTAT00000015373", "map_id": "ENSBTAT00000015373", "name": "AADAC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10086543", "map_id": "none", "name": "AHR:TCDD binds ARNT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035973", "map_id": "F1MYL2", "name": "ARNT2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035969", "map_id": "none", "name": "AHR:TCDD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10086469", "map_id": "none", "name": "NQO2:FAD dimer reduces quinones to hydroquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8936516", "map_id": "CHEBI:55458", "name": "RFDHN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8936520", "map_id": "CHEBI:36141", "name": "quinone", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8936514", "map_id": "CHEBI:15927", "name": "RFNA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8936507", "map_id": "CHEBI:17594", "name": "hydroquinone", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10086466", "map_id": "none", "name": "NQO2:FAD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SZT2", "map_id": "Q3SZT2", "name": "NQO2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072063", "map_id": "ENSBTAT00000072063", "name": "NQO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_209934", "map_id": "CHEBI:16796", "name": "MLT", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1130942", "map_id": "CHEBI:27881", "name": "resveratrol", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10077734", "map_id": "none", "name": "CMBL hydrolyses OM to OLMS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6786175", "map_id": "CHEBI:31932", "name": "OM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6786194", "map_id": "CHEBI:48416", "name": "OLMS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6786179", "map_id": "CHEBI:46640", "name": "diketone", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077731", "map_id": "A0A3Q1LGS8", "name": "CMBL", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072469", "map_id": "ENSBTAT00000072469", "name": "CMBL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10041241", "map_id": "none", "name": "Digestion of diacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10088973", "map_id": "none", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10088970", "map_id": "none", "name": "digestive LIPs", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10041239", "map_id": "none", "name": "Digestion of triacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10076274", "map_id": "none", "name": "DDAH1,2 hydrolyses ADMA to DMA and L-Cit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5693375", "map_id": "CHEBI:25682", "name": "ADMA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5693410", "map_id": "CHEBI:17170", "name": "DMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076271", "map_id": "none", "name": "DDAH1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P56965", "map_id": "P56965", "name": "DDAH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000049235", "map_id": "ENSBTAT00000049235", "name": "DDAH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SX44", "map_id": "Q3SX44", "name": "DDAH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085909", "map_id": "ENSBTAT00000085909", "name": "DDAH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040617", "map_id": "none", "name": "lactose + H2O => D-glucose + D-galactose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_188973", "map_id": "CHEBI:17716", "name": "Lac", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10040614", "map_id": "none", "name": "LCT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BK89", "map_id": "E1BK89", "name": "LCT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020185", "map_id": "ENSBTAT00000020185", "name": "LCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040872", "map_id": "none", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_191103", "map_id": "CHEBI:27931", "name": "maltotriose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_188986", "map_id": "CHEBI:17306", "name": "Mal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10040626", "map_id": "none", "name": "MGAM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10040620", "map_id": "none", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_189049", "map_id": "CHEBI:15824", "name": "Fru", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10040605", "map_id": "none", "name": "sucrase-isomaltase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BGH5", "map_id": "E1BGH5", "name": "SI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023366", "map_id": "ENSBTAT00000023366", "name": "SI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040608", "map_id": "none", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_189108", "map_id": "CHEBI:28912", "name": "limit dextrins", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10040595", "map_id": "none", "name": "Digestion of linear starch (amylose) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_189075", "map_id": "none", "name": "starch (amylose)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10040592", "map_id": "none", "name": "alpha-amylase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "F1MJQ3", "map_id": "F1MJQ3", "name": "AMY2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082976", "map_id": "ENSBTAT00000082976", "name": "AMY2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MP21", "map_id": "F1MP21", "name": "LOC539383", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060970", "map_id": "ENSBTAT00000060970", "name": "LOC539383", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LQY4", "map_id": "A0A3Q1LQY4", "name": "LOC112445748", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083621", "map_id": "ENSBTAT00000083621", "name": "LOC112445748", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040866", "map_id": "none", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10073378", "map_id": "none", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5659875", "map_id": "CHEBI:28189", "name": "iMal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10040629", "map_id": "none", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10040868", "map_id": "none", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10040870", "map_id": "none", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_189071", "map_id": "none", "name": "starch (amylopectin)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10086435", "map_id": "none", "name": "GUCY2C trimer binds GUCA2A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10086431", "map_id": "none", "name": "GUCY2C trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1N5B2", "map_id": "F1N5B2", "name": "GUCY2C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026286", "map_id": "ENSBTAT00000026286", "name": "GUCY2C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086425", "map_id": "none", "name": "GUCA2A,B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "E1BIM0", "map_id": "E1BIM0", "name": "GUCA2A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009466", "map_id": "ENSBTAT00000009466", "name": "GUCA2A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BIM1", "map_id": "E1BIM1", "name": "GUCA2B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009465", "map_id": "ENSBTAT00000009465", "name": "GUCA2B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10086433", "map_id": "none", "name": "GUCY2C trimer:GUCA2A,B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10036917", "map_id": "none", "name": "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10039865", "map_id": "none", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174393", "map_id": "CHEBI:17515", "name": "gGluCys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10039862", "map_id": "none", "name": "GCL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MN33", "map_id": "A0A3Q1MN33", "name": "GCLC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000081594", "map_id": "ENSBTAT00000081594", "name": "GCLC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2T9Y6", "map_id": "Q2T9Y6", "name": "GCLM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026855", "map_id": "ENSBTAT00000026855", "name": "GCLM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10087515", "map_id": "none", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1247934", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10071751", "map_id": "none", "name": "GGT dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10077658", "map_id": "none", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1247942", "map_id": "CHEBI:18183", "name": "OPRO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1247904", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10077655", "map_id": "none", "name": "CHAC1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6H738", "map_id": "A6H738", "name": "CHAC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013689", "map_id": "ENSBTAT00000013689", "name": "CHAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q0IIH4", "map_id": "Q0IIH4", "name": "CHAC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025922", "map_id": "ENSBTAT00000025922", "name": "CHAC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10057079", "map_id": "none", "name": "GGCT transforms gGluCys to OPRO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10057076", "map_id": "none", "name": "GGCT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q32LE4", "map_id": "Q32LE4", "name": "GGCT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014010", "map_id": "ENSBTAT00000014010", "name": "GGCT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075362", "map_id": "none", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_5688282", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10075353", "map_id": "P62894", "name": "CYCS", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5688281", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5688340", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10075359", "map_id": "none", "name": "SIRT5:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q3ZBQ0", "map_id": "Q3ZBQ0", "name": "SIRT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072664", "map_id": "ENSBTAT00000072664", "name": "SIRT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10075350", "map_id": "none", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10075337", "map_id": "none", "name": "Ack-ACCS2,AcK-GLUD,AcK-IDH2,Ack-SOD2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1MB37", "map_id": "A0A3Q1MB37", "name": "ACSS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5688337", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5688274", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10075341", "map_id": "none", "name": "ACCS2,GLUD,IDH2,SOD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10075347", "map_id": "none", "name": "SIRT3(?-399):Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10072271", "map_id": "none", "name": "TRIP11:IFT20 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10072269", "map_id": "none", "name": "IFT20:TRIP11", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q58CS6", "map_id": "Q58CS6", "name": "IFT20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084852", "map_id": "ENSBTAT00000084852", "name": "IFT20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10072263", "map_id": "Q58CS6", "name": "IFT20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10072267", "map_id": "A0A3Q1MQ84", "name": "TRIP11", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10058751", "map_id": "none", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10058748", "map_id": "none", "name": "CA1,2,3,7,13:Zinc", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MAE5", "map_id": "A0A3Q1MAE5", "name": "CA7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071702", "map_id": "ENSBTAT00000071702", "name": "CA7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q3SZX4", "map_id": "Q3SZX4", "name": "CA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020243", "map_id": "ENSBTAT00000020243", "name": "CA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058753", "map_id": "none", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10058719", "map_id": "none", "name": "CA4,9,14,12:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "A0A3Q1MI50", "map_id": "A0A3Q1MI50", "name": "CA14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000067395", "map_id": "ENSBTAT00000067395", "name": "CA14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BPA4", "map_id": "E1BPA4", "name": "CA9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015174", "map_id": "ENSBTAT00000015174", "name": "CA9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058755", "map_id": "none", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10058722", "map_id": "none", "name": "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10058772", "map_id": "none", "name": "Carbonic anhydrase dehydrates bicarbonate (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10058769", "map_id": "none", "name": "CA5A,B:Zinc", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "A0A3Q1LWK4", "map_id": "A0A3Q1LWK4", "name": "CA5A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068215", "map_id": "ENSBTAT00000068215", "name": "CA5A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N5D1", "map_id": "F1N5D1", "name": "CA5B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027210", "map_id": "ENSBTAT00000027210", "name": "CA5B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10058774", "map_id": "none", "name": "Carbonic anhydrase hydrates carbon dioxide (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10040030", "map_id": "none", "name": "GST trimers transfer GS from GSH to luminal substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_158543", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_176065", "map_id": "none", "name": "electrophilic substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "species_159211", "map_id": "CHEBI:30725", "name": "AFXBO", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:29132", "map_id": "CHEBI:29132", "name": "CHEBI:29132", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_176048", "map_id": "none", "name": "electrophilic substrate:SG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "CHEBI:32639", "map_id": "CHEBI:32639", "name": "CHEBI:32639", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2505", "map_id": "CHEBI:2505", "name": "CHEBI:2505", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:35896", "map_id": "CHEBI:35896", "name": "CHEBI:35896", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040027", "map_id": "none", "name": "MGST2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q2KJG4", "map_id": "Q2KJG4", "name": "MGST2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029028", "map_id": "ENSBTAT00000029028", "name": "MGST2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10067425", "map_id": "none", "name": "GSTK1 dimer transfers GS from GSH to CDNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3301954", "map_id": "CHEBI:34718", "name": "CDNB", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_3301969", "map_id": "CHEBI:8927", "name": "DNPSG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10067422", "map_id": "none", "name": "GSTK1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "F1MRG0", "map_id": "F1MRG0", "name": "GSTK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000012969", "map_id": "ENSBTAT00000012969", "name": "GSTK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10040021", "map_id": "none", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176070", "map_id": "none", "name": "Electrophilic substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:30614", "map_id": "CHEBI:30614", "name": "CHEBI:30614", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_176049", "map_id": "none", "name": "electrophilic substrate:SG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:34479", "map_id": "CHEBI:34479", "name": "CHEBI:34479", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10040018", "map_id": "none", "name": "GST dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BKD8", "map_id": "E1BKD8", "name": "GSTA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035828", "map_id": "ENSBTAT00000035828", "name": "GSTA5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MX44", "map_id": "F1MX44", "name": "GSTA5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O18879", "map_id": "O18879", "name": "GSTA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000046354", "map_id": "ENSBTAT00000046354", "name": "GSTA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q2NL00", "map_id": "Q2NL00", "name": "GSTT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007403", "map_id": "ENSBTAT00000007403", "name": "GSTT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A1A4L7", "map_id": "A1A4L7", "name": "GSTM4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000021896", "map_id": "ENSBTAT00000021896", "name": "GSTM4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LSN6", "map_id": "A0A3Q1LSN6", "name": "GSTM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085178", "map_id": "ENSBTAT00000085178", "name": "GSTM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10076133", "map_id": "none", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692212", "map_id": "CHEBI:81626", "name": "BaPtDHD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692216", "map_id": "CHEBI:87752", "name": "BaP-7,8-dione", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10040185", "map_id": "none", "name": "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_177153", "map_id": "CHEBI:8082", "name": "phenylacetate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_177137", "map_id": "CHEBI:15537", "name": "phenylacetyl-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10038316", "map_id": "none", "name": "The acetyl group from acetyl-CoA is transferred to the NAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038311", "map_id": "Q1JPA6", "name": "NAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000048506", "map_id": "ENSBTAT00000048506", "name": "NAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10038314", "map_id": "Q1JPA6", "name": "NAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10039918", "map_id": "none", "name": "The acetyl group from acetyl-CoA is transferred to the NAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10039921", "map_id": "none", "name": "NAT1 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174969", "map_id": "none", "name": "NAT1 substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:45373", "map_id": "CHEBI:45373", "name": "CHEBI:45373", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:30753", "map_id": "CHEBI:30753", "name": "CHEBI:30753", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:27565", "map_id": "CHEBI:27565", "name": "CHEBI:27565", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_174960", "map_id": "none", "name": "NAT1 acetylated conjugate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:63845", "map_id": "CHEBI:63845", "name": "CHEBI:63845", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16395", "map_id": "CHEBI:16395", "name": "CHEBI:16395", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63815", "map_id": "CHEBI:63815", "name": "CHEBI:63815", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:63817", "map_id": "CHEBI:63817", "name": "CHEBI:63817", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10039923", "map_id": "none", "name": "NAT2 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174971", "map_id": "none", "name": "NAT2 substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:6030", "map_id": "CHEBI:6030", "name": "CHEBI:6030", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_174958", "map_id": "none", "name": "NAT2 acetylated conjugate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:7207", "map_id": "CHEBI:7207", "name": "CHEBI:7207", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:32643", "map_id": "CHEBI:32643", "name": "CHEBI:32643", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071722", "map_id": "none", "name": "CYP3A4,5 hydroxylates AFB1 to AFQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5423605", "map_id": "CHEBI:2504", "name": "AFB1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5423660", "map_id": "CHEBI:78582", "name": "AFQ1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071719", "map_id": "none", "name": "CYP3A4,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10071754", "map_id": "none", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5490253", "map_id": "none", "name": "AFXBO-SG,AFNBO-SG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78581", "map_id": "CHEBI:78581", "name": "CHEBI:78581", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78587", "map_id": "CHEBI:78587", "name": "CHEBI:78587", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5490235", "map_id": "none", "name": "AFXBO-CG,AFNBO-CG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78579", "map_id": "CHEBI:78579", "name": "CHEBI:78579", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78584", "map_id": "CHEBI:78584", "name": "CHEBI:78584", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10038060", "map_id": "none", "name": "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10038057", "map_id": "none", "name": "CYP1A2,3A4,3A5,2A13", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10071727", "map_id": "none", "name": "CYP1A2, 3A4 oxidise AFB1 to AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5423663", "map_id": "CHEBI:78586", "name": "AFNBO", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10071724", "map_id": "none", "name": "CYP1A2,3A4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10071729", "map_id": "none", "name": "CYP1A2 hydroxylates AFB1 to AFM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5423629", "map_id": "CHEBI:78576", "name": "AFM1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10071712", "map_id": "none", "name": "AKR dimers reduce AFBDHO to AFBDOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5423727", "map_id": "CHEBI:53107", "name": "AFBDHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5423729", "map_id": "CHEBI:53108", "name": "AFBDOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10071709", "map_id": "none", "name": "AKR dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MZC0", "map_id": "F1MZC0", "name": "AKR7A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016300", "map_id": "ENSBTAT00000016300", "name": "AKR7A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6I4", "map_id": "F1N6I4", "name": "LOC788425", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000038217", "map_id": "ENSBTAT00000038217", "name": "LOC788425", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071715", "map_id": "none", "name": "CYP2A13 oxidises AFM1 to AFM1E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5423657", "map_id": "CHEBI:78577", "name": "AFM1E", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035869", "map_id": "G3MYH2", "name": "LOC540707", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10071763", "map_id": "none", "name": "ACY1:Zn2+ dimer hydrolyses mercapturic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5490236", "map_id": "none", "name": "AFXBO-NAC,AFNBO-NAC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:78580", "map_id": "CHEBI:78580", "name": "CHEBI:78580", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78585", "map_id": "CHEBI:78585", "name": "CHEBI:78585", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5490231", "map_id": "none", "name": "AFXBO-C,AFNBO-C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:78583", "map_id": "CHEBI:78583", "name": "CHEBI:78583", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78578", "map_id": "CHEBI:78578", "name": "CHEBI:78578", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071760", "map_id": "none", "name": "ACY1:Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MR63", "map_id": "F1MR63", "name": "ACY1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000024787", "map_id": "ENSBTAT00000024787", "name": "ACY1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10071717", "map_id": "none", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5423723", "map_id": "none", "name": "AFXBO,AFNBO", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5423730", "map_id": "none", "name": "AFXBO-SG,AFNBO-SG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10074761", "map_id": "none", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10074753", "map_id": "F6PSE2", "name": "NBN", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10074751", "map_id": "Q3SYV6", "name": "KPNA2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000016216", "map_id": "ENSBTAT00000016216", "name": "KPNA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074755", "map_id": "none", "name": "NBN:KPNA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SYV6", "map_id": "Q3SYV6", "name": "KPNA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035720", "map_id": "none", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035716", "map_id": "F6PSE2", "name": "NBN", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035710", "map_id": "none", "name": "RAD50:MRE11A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10035712", "map_id": "none", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035708", "map_id": "E1BIN9", "name": "MRE11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10035704", "map_id": "G3X6W2", "name": "RAD50", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10074759", "map_id": "none", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074757", "map_id": "Q3SYV6", "name": "KPNA2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10074747", "map_id": "none", "name": "APBB1 and MAPK8 bind diphosphorylated H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074743", "map_id": "A0A3Q1MU04", "name": "APBB1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000069360", "map_id": "ENSBTAT00000069360", "name": "APBB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074733", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074745", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome:APBB1:p-T,Y-MAPK8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MU04", "map_id": "A0A3Q1MU04", "name": "APBB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074558", "map_id": "none", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074548", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1B782", "map_id": "E1B782", "name": "HERC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000018496", "map_id": "ENSBTAT00000018496", "name": "HERC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1BI26", "map_id": "E1BI26", "name": "MDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000035900", "map_id": "ENSBTAT00000035900", "name": "MDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FV15", "map_id": "A4FV15", "name": "PIAS4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000001000", "map_id": "ENSBTAT00000001000", "name": "PIAS4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074555", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074736", "map_id": "none", "name": "ATM phosphorylates EYA1-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074724", "map_id": "A0A3Q1M345", "name": "EYA3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000074020", "map_id": "ENSBTAT00000074020", "name": "EYA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074727", "map_id": "A0A3Q1M345", "name": "phospho-EYA3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10074739", "map_id": "none", "name": "EYA1-4 dephosphorylates tyrosine Y142 of H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074663", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074677", "map_id": "none", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074674", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074667", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074679", "map_id": "none", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074542", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074544", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074550", "map_id": "none", "name": "HERC2 and PIAS4 are recruited to DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10069303", "map_id": "A4FV15", "name": "PIAS4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10074546", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10069553", "map_id": "E1B782", "name": "HERC2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10076329", "map_id": "none", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076288", "map_id": "none", "name": "MDC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10076290", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076332", "map_id": "none", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074530", "map_id": "none", "name": "DNA DSB:p-MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076303", "map_id": "none", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076300", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076334", "map_id": "none", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074715", "map_id": "none", "name": "p-Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10074670", "map_id": "none", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10074720", "map_id": "none", "name": "WICH phosphorylates H2AFX on Y142", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074711", "map_id": "none", "name": "H2AFX-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10074717", "map_id": "none", "name": "WICH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076293", "map_id": "none", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10074665", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075173", "map_id": "none", "name": "Activated ATM phosphorylates ABL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075167", "map_id": "A0A3Q1LI98", "name": "ABL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10049230", "map_id": "none", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_429926", "map_id": "none", "name": "capped oligoribonucleotide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_430042", "map_id": "CHEBI:17825", "name": "7MGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429925", "map_id": "none", "name": "oligoribonucleotide with a 5'-diphosphate", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049227", "map_id": "G5E535", "name": "DCPS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000003732", "map_id": "ENSBTAT00000003732", "name": "DCPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10049232", "map_id": "none", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10049219", "map_id": "none", "name": "Lsm1-7 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QQV3", "map_id": "A6QQV3", "name": "LSM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000007405", "map_id": "ENSBTAT00000007405", "name": "LSM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DIA6", "map_id": "A0A452DIA6", "name": "LSM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009684", "map_id": "ENSBTAT00000009684", "name": "LSM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N6T3", "map_id": "F1N6T3", "name": "LSM7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000005939", "map_id": "ENSBTAT00000005939", "name": "LSM7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M2U2", "map_id": "A0A3Q1M2U2", "name": "LSM5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069947", "map_id": "ENSBTAT00000069947", "name": "LSM5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LMH1", "map_id": "A0A3Q1LMH1", "name": "PATL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000072254", "map_id": "ENSBTAT00000072254", "name": "PATL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LRX5", "map_id": "A0A3Q1LRX5", "name": "LSM6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077566", "map_id": "ENSBTAT00000077566", "name": "LSM6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429974", "map_id": "none", "name": "mature mRNA (eukaryotic, capped and deadenylated)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049221", "map_id": "none", "name": "Deadenylated mRNA:Lsm1-7 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10061043", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2024002", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2024016", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10060960", "map_id": "F1N1D8", "name": "MINPP1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "ENSBTAT00000007784", "map_id": "ENSBTAT00000007784", "name": "MINPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060963", "map_id": "none", "name": "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2024008", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2024012", "map_id": "CHEBI:16067", "name": "I(1,4,5,6)P4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10061122", "map_id": "none", "name": "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_2024018", "map_id": "CHEBI:17401", "name": "IP6", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_2564836", "map_id": "CHEBI:16507", "name": "I(1,2,4,5,6)P5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "reaction_10036907", "map_id": "none", "name": "Formation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035351", "map_id": "none", "name": "PPAT dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17909", "map_id": "CHEBI:17909", "name": "CHEBI:17909", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MV22", "map_id": "F1MV22", "name": "PPAT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000052667", "map_id": "ENSBTAT00000052667", "name": "PPAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036905", "map_id": "none", "name": "PPAT tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_29602", "map_id": "CHEBI:17202", "name": "IMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035339", "map_id": "none", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111369", "map_id": "CHEBI:18413", "name": "FGAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111370", "map_id": "CHEBI:28843", "name": "AIR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035336", "map_id": "Q59A32", "name": "GART", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000012108", "map_id": "ENSBTAT00000012108", "name": "GART", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035354", "map_id": "none", "name": "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111292", "map_id": "CHEBI:17284", "name": "PRA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10036909", "map_id": "none", "name": "Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10035308", "map_id": "none", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111584", "map_id": "CHEBI:15652", "name": "XMP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035305", "map_id": "A0A3Q1LUN6", "name": "GMPS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000084984", "map_id": "ENSBTAT00000084984", "name": "GMPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10091727", "map_id": "none", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678719", "map_id": "none", "name": "IMPDH inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035314", "map_id": "none", "name": "IMPDH2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10035317", "map_id": "none", "name": "IMPDH tetramers:IMPDH inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10035342", "map_id": "none", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111338", "map_id": "CHEBI:18349", "name": "PRGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_419151", "map_id": "CHEBI:15637", "name": "10-formyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111354", "map_id": "CHEBI:18272", "name": "N-Formyl-GAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035345", "map_id": "none", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10035329", "map_id": "none", "name": "CAIR + Aspartate + ATP => SAICAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111395", "map_id": "CHEBI:28413", "name": "CAIR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111399", "map_id": "CHEBI:18319", "name": "SAICAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035326", "map_id": "none", "name": "PAICS octamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MN04", "map_id": "F1MN04", "name": "PAICS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000013985", "map_id": "ENSBTAT00000013985", "name": "PAICS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036928", "map_id": "none", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35141", "map_id": "CHEBI:15919", "name": "ADS", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10036925", "map_id": "none", "name": "adenylosuccinate synthetase holoenzyme dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MBG0", "map_id": "A7MBG0", "name": "ADSS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047061", "map_id": "ENSBTAT00000047061", "name": "ADSS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035332", "map_id": "none", "name": "AIR + CO2 => CAIR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10035319", "map_id": "none", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10076312", "map_id": "none", "name": "DNA-PKcs autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076309", "map_id": "none", "name": "PRKDC:XRCC5:XRCC6:DNA DSB ends", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "E1BLB6", "map_id": "E1BLB6", "name": "PRKDC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022631", "map_id": "ENSBTAT00000022631", "name": "PRKDC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10075286", "map_id": "none", "name": "p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:DNA DSB ends", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076347", "map_id": "none", "name": "Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076305", "map_id": "E1BLB6", "name": "PRKDC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10076345", "map_id": "none", "name": "XRCC5:XRCC6:DNA DSBs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10075295", "map_id": "none", "name": "PRKDC phosphorylates DCLRE1C at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10075288", "map_id": "none", "name": "p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S645-DCLRE1C:DNA DSB ends", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10075292", "map_id": "none", "name": "p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:DNA DSB ends", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076286", "map_id": "none", "name": "DCLRE1C (ARTEMIS) processes DNA DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076283", "map_id": "none", "name": "p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:Trimmed DNA DSB ends", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10076327", "map_id": "none", "name": "TDP1 and TDP2 process unligatable DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10076314", "map_id": "none", "name": "p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:Ligatable DNA DSB ends", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10076324", "map_id": "none", "name": "(TDP1,TDP2)", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10036649", "map_id": "none", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500759", "map_id": "none", "name": "Cyt-Rib, Ura-Rib", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500761", "map_id": "none", "name": "CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036646", "map_id": "none", "name": "UCK2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LZ00", "map_id": "A0A3Q1LZ00", "name": "UCK2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077740", "map_id": "ENSBTAT00000077740", "name": "UCK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034989", "map_id": "none", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034986", "map_id": "none", "name": "UCK1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A452DII0", "map_id": "A0A452DII0", "name": "UCK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000014316", "map_id": "ENSBTAT00000014316", "name": "UCK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035020", "map_id": "none", "name": "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035017", "map_id": "none", "name": "TK1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NEX0", "map_id": "A0A3Q1NEX0", "name": "TK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073714", "map_id": "ENSBTAT00000073714", "name": "TK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035007", "map_id": "none", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500829", "map_id": "none", "name": "Cyt-Rib, dC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:15698", "map_id": "CHEBI:15698", "name": "CHEBI:15698", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500430", "map_id": "none", "name": "(d)Ura", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16450", "map_id": "CHEBI:16450", "name": "CHEBI:16450", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035004", "map_id": "none", "name": "CDA tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10088624", "map_id": "none", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10088621", "map_id": "A0A3Q1MGP5", "name": "UCKL1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000071389", "map_id": "ENSBTAT00000071389", "name": "UCKL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034980", "map_id": "none", "name": "(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500828", "map_id": "none", "name": "(d)CMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_109378", "map_id": "CHEBI:15918", "name": "dCMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10034977", "map_id": "none", "name": "DCK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3MHR2", "map_id": "Q3MHR2", "name": "DCK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016449", "map_id": "ENSBTAT00000016449", "name": "DCK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035479", "map_id": "none", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_83962", "map_id": "CHEBI:17568", "name": "Ura", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10035476", "map_id": "none", "name": "UPP1, UPP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1N0Y0", "map_id": "F1N0Y0", "name": "UPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000011088", "map_id": "ENSBTAT00000011088", "name": "UPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1MGK3", "map_id": "A0A3Q1MGK3", "name": "UPP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000082335", "map_id": "ENSBTAT00000082335", "name": "UPP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036614", "map_id": "none", "name": "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_500822", "map_id": "none", "name": "dC, Thy-dRib, dU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_500823", "map_id": "none", "name": "dCMP, TMP, dUMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_500742", "map_id": "CHEBI:17622", "name": "dUMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10036611", "map_id": "G3N1H3", "name": "TK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000064369", "map_id": "ENSBTAT00000064369", "name": "TK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10069313", "map_id": "none", "name": "Laminins bind HSPG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10069309", "map_id": "none", "name": "Laminins with alpha-1, -2 or -5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1N3A0", "map_id": "A0A3Q1N3A0", "name": "LAMA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000073403", "map_id": "ENSBTAT00000073403", "name": "LAMA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1N0T1", "map_id": "F1N0T1", "name": "LAMC3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000023245", "map_id": "ENSBTAT00000023245", "name": "LAMC3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10069311", "map_id": "none", "name": "Laminins with alpha-1, -2 or -5:HSPG2(22-4391)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10044515", "map_id": "none", "name": "Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10044511", "map_id": "none", "name": "Laminins-332, 511, 521, (211, 221)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10044513", "map_id": "none", "name": "Integrin alpha3beta1, alpha6beta4:Laminins-332, 511, 521, (211, 221)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10065555", "map_id": "none", "name": "Laminins:Nidogens binds collagen type IV networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10065551", "map_id": "none", "name": "Laminins with gamma-1, gamma-3:Nidogens 1,2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A3Q1N9E9", "map_id": "A0A3Q1N9E9", "name": "LAMA4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069112", "map_id": "ENSBTAT00000069112", "name": "LAMA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MDD5", "map_id": "F1MDD5", "name": "LAMA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000060991", "map_id": "ENSBTAT00000060991", "name": "LAMA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6QNS6", "map_id": "A6QNS6", "name": "NID1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009531", "map_id": "ENSBTAT00000009531", "name": "NID1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065553", "map_id": "none", "name": "Laminins with gamma-1, gamma-3:Nidogens:Collagen type IV network", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10047065", "map_id": "none", "name": "FAR2 reduces PalmCoA to HXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_8848577", "map_id": "CHEBI:16125", "name": "HXOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10047062", "map_id": "Q0P5J1", "name": "FAR2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "ENSBTAT00000014725", "map_id": "ENSBTAT00000014725", "name": "FAR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083577", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_30209", "map_id": "CHEBI:17336", "name": "atROL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2534407", "map_id": "CHEBI:17616", "name": "atR-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10083575", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8848499", "map_id": "CHEBI:75584", "name": "PALM-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091611", "map_id": "none", "name": "BIL dissociates from GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091609", "map_id": "none", "name": "BIL:GSTA1, FABP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10091607", "map_id": "none", "name": "GSTA1, FABP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_189386", "map_id": "CHEBI:16990", "name": "BIL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10091613", "map_id": "none", "name": "BIL binds GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10091598", "map_id": "none", "name": "SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9661418", "map_id": "CHEBI:16990", "name": "BIL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10091605", "map_id": "none", "name": "SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10091602", "map_id": "F1MYV0", "name": "SLCO1B3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10069412", "map_id": "none", "name": "Endorepellin binds KDR (VEGFR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10069410", "map_id": "none", "name": "HSPG2(3687-4391):KDR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10074474", "map_id": "none", "name": "ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10074459", "map_id": "none", "name": "ABCA1 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "F1MG24", "map_id": "F1MG24", "name": "ABCA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000027538", "map_id": "ENSBTAT00000027538", "name": "ABCA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10074467", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10074471", "map_id": "E1B8S9", "name": "ZDHHC8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000006197", "map_id": "ENSBTAT00000006197", "name": "ZDHHC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10074486", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10074478", "map_id": "none", "name": "4xPALM-C-ABCA1 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10076091", "map_id": "none", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10076089", "map_id": "none", "name": "CANDI:CUL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10059181", "map_id": "none", "name": "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5691103", "map_id": "CHEBI:78619", "name": "Fe(3+)O(OH)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10059178", "map_id": "none", "name": "Ferritin Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10076083", "map_id": "none", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10076005", "map_id": "A0A3Q1MUL6", "name": "IREB2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000077304", "map_id": "ENSBTAT00000077304", "name": "IREB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10076074", "map_id": "A0A3Q1MUL6", "name": "IREB2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10076080", "map_id": "none", "name": "SKP1:FBXL5:CUL1:NEDD8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10052866", "map_id": "none", "name": "CYBRD1:Heme reduces Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_917828", "map_id": "CHEBI:10545", "name": "e-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10052863", "map_id": "none", "name": "CYBRD1:Heme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "F1MLZ1", "map_id": "F1MLZ1", "name": "CYBRD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000010387", "map_id": "ENSBTAT00000010387", "name": "CYBRD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10052916", "map_id": "none", "name": "apoTF binds 2Fe3+ to form holoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10087646", "map_id": "none", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_2889072", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_8949220", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8949232", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_2889083", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10087643", "map_id": "A0A3Q1LSB1", "name": "SLC8B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10061116", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629755", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10060953", "map_id": "Q0II95", "name": "IP6K1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060956", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629765", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629759", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10061040", "map_id": "none", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060977", "map_id": "none", "name": "NUDT(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A2VDV0", "map_id": "A2VDV0", "name": "NUDT4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000009797", "map_id": "ENSBTAT00000009797", "name": "NUDT4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A7MBH2", "map_id": "A7MBH2", "name": "NUDT11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085197", "map_id": "ENSBTAT00000085197", "name": "NUDT11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061011", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10061008", "map_id": "E1BGX9", "name": "IPPK", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10060980", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023968", "map_id": "none", "name": "(PP)2-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1629732", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:62924", "map_id": "CHEBI:62924", "name": "CHEBI:62924", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060983", "map_id": "none", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023943", "map_id": "none", "name": "PP-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1629736", "map_id": "CHEBI:62926", "name": "1-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:62927", "map_id": "CHEBI:62927", "name": "CHEBI:62927", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10060969", "map_id": "none", "name": "NUDT4:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10061079", "map_id": "none", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629740", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10061021", "map_id": "A0A3Q1M2A3", "name": "PPIP5K2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000072742", "map_id": "ENSBTAT00000072742", "name": "PPIP5K2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061034", "map_id": "none", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629738", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10063018", "map_id": "none", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023974", "map_id": "none", "name": "1/3-PP-IP5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:62922", "map_id": "CHEBI:62922", "name": "CHEBI:62922", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061037", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10063020", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061024", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061125", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10061113", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10061110", "map_id": "none", "name": "PLCdegh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BJE0", "map_id": "E1BJE0", "name": "PLCD3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000034821", "map_id": "ENSBTAT00000034821", "name": "PLCD3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MTE8", "map_id": "F1MTE8", "name": "PLCE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000078103", "map_id": "ENSBTAT00000078103", "name": "PLCE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M8P8", "map_id": "A0A3Q1M8P8", "name": "PLCH2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000085120", "map_id": "ENSBTAT00000085120", "name": "PLCH2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061084", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994170", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10061081", "map_id": "none", "name": "INPP5(3)/ITPK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10061006", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10061003", "map_id": "none", "name": "PLCbz", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q1RML2", "map_id": "Q1RML2", "name": "PLCZ1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017574", "map_id": "ENSBTAT00000017574", "name": "PLCZ1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10060917", "map_id": "none", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10060914", "map_id": "none", "name": "ITPKA/B/C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1LNH2", "map_id": "A0A3Q1LNH2", "name": "ITPKB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070709", "map_id": "ENSBTAT00000070709", "name": "ITPKB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MN32", "map_id": "F1MN32", "name": "ITPKC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000025930", "map_id": "ENSBTAT00000025930", "name": "ITPKC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A4FV33", "map_id": "A4FV33", "name": "ITPKA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000002194", "map_id": "ENSBTAT00000002194", "name": "ITPKA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10061076", "map_id": "none", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2023856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10061073", "map_id": "none", "name": "PLD4:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A0A3Q1LJY0", "map_id": "A0A3Q1LJY0", "name": "PLD4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000074483", "map_id": "ENSBTAT00000074483", "name": "PLD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036003", "map_id": "none", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10034244", "map_id": "Q3ZBJ1", "name": "NCBP2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10034248", "map_id": "E1BMM0", "name": "NCBP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10034250", "map_id": "none", "name": "Cap Binding Complex (CBC)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10084424", "map_id": "none", "name": "CIDEA:CIDEC binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13977", "compartment_display": "lipid droplet" }, { "id": "species_10084420", "map_id": "none", "name": "CIDEA:CIDEC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A4FUX1", "map_id": "A4FUX1", "name": "CIDEA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083406", "map_id": "ENSBTAT00000083406", "name": "CIDEA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1LUM0", "map_id": "A0A3Q1LUM0", "name": "CIDEC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000079299", "map_id": "ENSBTAT00000079299", "name": "CIDEC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8866926", "map_id": "none", "name": "lipid droplet", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "species_10084422", "map_id": "none", "name": "CIDEA:CIDEC:lipid droplet", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "reaction_10084480", "map_id": "none", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10084476", "map_id": "none", "name": "FITM1,FITM2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "A4IFN5", "map_id": "A4IFN5", "name": "FITM2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026679", "map_id": "ENSBTAT00000026679", "name": "FITM2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A452DJ11", "map_id": "A0A452DJ11", "name": "FITM1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000028518", "map_id": "ENSBTAT00000028518", "name": "FITM1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084478", "map_id": "none", "name": "(FITM1,FITM2):TAGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10084694", "map_id": "none", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10084690", "map_id": "Q29RS1", "name": "HSD17B13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000038453", "map_id": "ENSBTAT00000038453", "name": "HSD17B13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10084692", "map_id": "none", "name": "HSD17B13:lipid droplet", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "true" }, { "id": "Q29RS1", "map_id": "Q29RS1", "name": "HSD17B13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083544", "map_id": "none", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10083541", "map_id": "G3X777", "name": "PNPLA4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000021067", "map_id": "ENSBTAT00000021067", "name": "PNPLA4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10083547", "map_id": "none", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10071388", "map_id": "none", "name": "FABPs bind LCFAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10071384", "map_id": "none", "name": "FABPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MHQ4", "map_id": "F1MHQ4", "name": "FABP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000079", "map_id": "ENSBTAT00000000079", "name": "FABP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09139", "map_id": "Q09139", "name": "FABP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000017593", "map_id": "ENSBTAT00000017593", "name": "FABP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MFF7", "map_id": "F1MFF7", "name": "FABP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022662", "map_id": "ENSBTAT00000022662", "name": "FABP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MRS8", "map_id": "F1MRS8", "name": "FABP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000000867", "map_id": "ENSBTAT00000000867", "name": "FABP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10790", "map_id": "P10790", "name": "FABP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000022375", "map_id": "ENSBTAT00000022375", "name": "FABP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "G3N125", "map_id": "G3N125", "name": "FABP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000066006", "map_id": "ENSBTAT00000066006", "name": "FABP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10071386", "map_id": "none", "name": "FABPs:LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10035435", "map_id": "none", "name": "Adenine + PRPP => AMP + PPi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035432", "map_id": "none", "name": "APRT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10051215", "map_id": "none", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10051212", "map_id": "none", "name": "GMPR tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MCZ0", "map_id": "F1MCZ0", "name": "GMPR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000003519", "map_id": "ENSBTAT00000003519", "name": "GMPR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F6R1R5", "map_id": "F6R1R5", "name": "GMPR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020904", "map_id": "ENSBTAT00000020904", "name": "GMPR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036001", "map_id": "none", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035998", "map_id": "none", "name": "AMPD tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "F1MLX6", "map_id": "F1MLX6", "name": "AMPD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000015348", "map_id": "ENSBTAT00000015348", "name": "AMPD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0A3Q1M723", "map_id": "A0A3Q1M723", "name": "AMPD2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000080896", "map_id": "ENSBTAT00000080896", "name": "AMPD2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035426", "map_id": "none", "name": "dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_500224", "map_id": "none", "name": "dA, dG, dI", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_500222", "map_id": "none", "name": "dAMP, dGMP, dIMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10035423", "map_id": "none", "name": "DGUOK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q2KIN2", "map_id": "Q2KIN2", "name": "DGUOK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047239", "map_id": "ENSBTAT00000047239", "name": "DGUOK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036306", "map_id": "none", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500173", "map_id": "none", "name": "Ade-Rib, dA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500088", "map_id": "none", "name": "(d)AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036303", "map_id": "none", "name": "ADK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MB39", "map_id": "A0A3Q1MB39", "name": "ADK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000071820", "map_id": "ENSBTAT00000071820", "name": "ADK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036308", "map_id": "none", "name": "deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500201", "map_id": "none", "name": "dA, dG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500199", "map_id": "none", "name": "dAMP, dGMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10035444", "map_id": "none", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500259", "map_id": "none", "name": "Gua, Hyp", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500260", "map_id": "none", "name": "GMP, IMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10035441", "map_id": "none", "name": "HGPRT tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q3SZ18", "map_id": "Q3SZ18", "name": "HPRT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000019547", "map_id": "ENSBTAT00000019547", "name": "HPRT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050378", "map_id": "none", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050287", "map_id": "Q3ZCE2", "name": "ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "ENSBTAT00000000805", "map_id": "ENSBTAT00000000805", "name": "phospho-ELAVL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050298", "map_id": "Q3ZCE2", "name": "phospho-ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050375", "map_id": "A0A3Q1MRR6", "name": "PRKCD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10050368", "map_id": "none", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450613", "map_id": "none", "name": "mRNA Transcript Targeted by HuR with Unknown Phosphorylation", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050289", "map_id": "none", "name": "HuR with Unknown Phosphorylation: mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q3ZCE2", "map_id": "Q3ZCE2", "name": "phospho-ELAVL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050400", "map_id": "none", "name": "HuR:mRNA complex translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050304", "map_id": "none", "name": "HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P51122", "map_id": "P51122", "name": "ANP32A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000016410", "map_id": "ENSBTAT00000016410", "name": "ANP32A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MH31", "map_id": "F1MH31", "name": "NUP214", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029190", "map_id": "ENSBTAT00000029190", "name": "NUP214", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050398", "map_id": "none", "name": "HuR:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10050382", "map_id": "Q3ZBM0", "name": "phospho-TNFSF13", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10051219", "map_id": "none", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050293", "map_id": "Q3ZCE2", "name": "phospho-ELAVL1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_450605", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050295", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine158:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10050306", "map_id": "none", "name": "HuR binds the CRM1 nuclear export machinery", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10050261", "map_id": "Q3ZBM0", "name": "phospho-TNFSF13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050273", "map_id": "F1MH31", "name": "NUP214", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050302", "map_id": "none", "name": "HuR:mRNA complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10050269", "map_id": "P51122", "name": "ANP32A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10051221", "map_id": "none", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_517622", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050300", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine318:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10051066", "map_id": "none", "name": "p-S54,92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050363", "map_id": "none", "name": "Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A7MB98", "map_id": "A7MB98", "name": "phospho-ZFP36L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000084778", "map_id": "ENSBTAT00000084778", "name": "phospho-ZFP36L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10051064", "map_id": "none", "name": "Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050366", "map_id": "none", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050357", "map_id": "none", "name": "BRF1:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050318", "map_id": "none", "name": "p-S92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050314", "map_id": "none", "name": "Phosphorylated BRF1 (Ser92, Ser203):mRNA Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10050316", "map_id": "none", "name": "Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10050373", "map_id": "none", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_450523", "map_id": "none", "name": "mRNA Transcript Targeted by BRF1", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050355", "map_id": "A7MB98", "name": "ZFP36L1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10050408", "map_id": "none", "name": "p-S193-KSRP binds 14-3-3zeta in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050402", "map_id": "P63103", "name": "YWHAZ", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10050371", "map_id": "A0A3Q1N6L6", "name": "phospho-KHSRP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000070369", "map_id": "ENSBTAT00000070369", "name": "phospho-KHSRP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10050406", "map_id": "none", "name": "Phosphorylated KSRP (Ser193):14-3-3zeta Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1N6L6", "map_id": "A0A3Q1N6L6", "name": "phospho-KHSRP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10050380", "map_id": "none", "name": "KSRP binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10050322", "map_id": "A0A3Q1N6L6", "name": "KHSRP", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_450386", "map_id": "none", "name": "mRNA Transcript Targeted by KSRP", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10050324", "map_id": "none", "name": "KSRP:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10049346", "map_id": "none", "name": "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_400452", "map_id": "CHEBI:15756", "name": "PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10049343", "map_id": "P26201", "name": "CD36", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10049351", "map_id": "none", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1132084", "map_id": "CHEBI:33019", "name": "PPi(3-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10049348", "map_id": "F1MEX9", "name": "ACSL3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10044634", "map_id": "none", "name": "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10044615", "map_id": "none", "name": "KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_6790050", "map_id": "none", "name": "Mg2+:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10044619", "map_id": "none", "name": "KCNJ11:ATP tetramer:ABCC8 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10047765", "map_id": "none", "name": "Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10034971", "map_id": "none", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109382", "map_id": "CHEBI:17622", "name": "dUMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034968", "map_id": "none", "name": "DCTD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A6QQC3", "map_id": "A6QQC3", "name": "DCTD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000083533", "map_id": "ENSBTAT00000083533", "name": "DCTD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035038", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10035035", "map_id": "none", "name": "CTPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0JNE9", "map_id": "A0JNE9", "name": "CTPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000068403", "map_id": "ENSBTAT00000068403", "name": "CTPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035698", "map_id": "none", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500006", "map_id": "none", "name": "(d)CDP, UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28846", "map_id": "CHEBI:28846", "name": "CHEBI:28846", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500009", "map_id": "none", "name": "(d)CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10034909", "map_id": "A0A452DIX8", "name": "CMPK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000026582", "map_id": "ENSBTAT00000026582", "name": "CMPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035029", "map_id": "none", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_499997", "map_id": "none", "name": "dUMP, TMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_499999", "map_id": "none", "name": "dUDP, TDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28850", "map_id": "CHEBI:28850", "name": "CHEBI:28850", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10035026", "map_id": "none", "name": "DTYMK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1N7A8", "map_id": "A0A3Q1N7A8", "name": "DTYMK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000069715", "map_id": "ENSBTAT00000069715", "name": "DTYMK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036692", "map_id": "none", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036689", "map_id": "P08166", "name": "AK2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "ENSBTAT00000023406", "map_id": "ENSBTAT00000023406", "name": "AK2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10034998", "map_id": "none", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10034995", "map_id": "none", "name": "TS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1NID0", "map_id": "A0A3Q1NID0", "name": "TYMS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000077973", "map_id": "ENSBTAT00000077973", "name": "TYMS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036683", "map_id": "none", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788782", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16174", "map_id": "CHEBI:16174", "name": "CHEBI:16174", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_6788778", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10036680", "map_id": "none", "name": "AK5,7,8,9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MKM8", "map_id": "A0A3Q1MKM8", "name": "AK5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000076708", "map_id": "ENSBTAT00000076708", "name": "AK5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "E1B7Q2", "map_id": "E1B7Q2", "name": "AK7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000061550", "map_id": "ENSBTAT00000061550", "name": "AK7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "F1MUF5", "map_id": "F1MUF5", "name": "AK9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000020294", "map_id": "ENSBTAT00000020294", "name": "AK9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036938", "map_id": "none", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036935", "map_id": "G8JKV3", "name": "2xHC-GLRX", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "ENSBTAT00000001575", "map_id": "ENSBTAT00000001575", "name": "GLRX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10036932", "map_id": "G8JKV3", "name": "GLRX", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10036685", "map_id": "none", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10051075", "map_id": "none", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_482803", "map_id": "none", "name": "(d)NDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:28862", "map_id": "CHEBI:28862", "name": "CHEBI:28862", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_482807", "map_id": "none", "name": "(d)NTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_500739", "map_id": "CHEBI:17625", "name": "dUTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10051072", "map_id": "none", "name": "NME4 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "F1N6T4", "map_id": "F1N6T4", "name": "NME4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000047964", "map_id": "ENSBTAT00000047964", "name": "NME4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10077890", "map_id": "none", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6788802", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_6788801", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10077887", "map_id": "Q0VCP1", "name": "AK4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000043366", "map_id": "ENSBTAT00000043366", "name": "AK4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10082948", "map_id": "none", "name": "NUDT13 hydrolyses AP6A to AP4 and ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6810468", "map_id": "CHEBI:63689", "name": "AP6A", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6810471", "map_id": "CHEBI:58450", "name": "AP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10082945", "map_id": "Q1RMI9", "name": "NUDT13", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "ENSBTAT00000000407", "map_id": "ENSBTAT00000000407", "name": "NUDT13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035047", "map_id": "none", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10035044", "map_id": "none", "name": "DUT trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "A0A3Q1MT44", "map_id": "A0A3Q1MT44", "name": "DUT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000070515", "map_id": "ENSBTAT00000070515", "name": "DUT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10035481", "map_id": "none", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10034953", "map_id": "none", "name": "5,6-dihydrouracil + H2O => beta-ureidopropionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73584", "map_id": "CHEBI:15901", "name": "5,6-Dihydrouracil", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73588", "map_id": "CHEBI:18261", "name": "UPROP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034950", "map_id": "none", "name": "DPYS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "E1BFN6", "map_id": "E1BFN6", "name": "DPYS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000029176", "map_id": "ENSBTAT00000029176", "name": "DPYS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036267", "map_id": "none", "name": "TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_500420", "map_id": "none", "name": "TMP, UMP, dU5MP, U2MP, U3MP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:28895", "map_id": "CHEBI:28895", "name": "CHEBI:28895", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28070", "map_id": "CHEBI:28070", "name": "CHEBI:28070", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500421", "map_id": "none", "name": "Thy-dRib, Ura-Rib, dU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10036264", "map_id": "none", "name": "NT5M dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "E1B8C1", "map_id": "E1B8C1", "name": "NT5M", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000043576", "map_id": "ENSBTAT00000043576", "name": "NT5M", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036209", "map_id": "none", "name": "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_500316", "map_id": "none", "name": "CMP, TMP, UMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_500318", "map_id": "none", "name": "Cyt-Rib, Thy-dRib, Ura-Rib", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10035009", "map_id": "none", "name": "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73541", "map_id": "CHEBI:27468", "name": "5,6-Dihydrothymine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73617", "map_id": "CHEBI:1670", "name": "UIBA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10035011", "map_id": "none", "name": "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73619", "map_id": "CHEBI:16320", "name": "3AIB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10034959", "map_id": "none", "name": "UPB1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "A0A3Q1MFR9", "map_id": "A0A3Q1MFR9", "name": "UPB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000086038", "map_id": "ENSBTAT00000086038", "name": "UPB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10036258", "map_id": "none", "name": "TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500414", "map_id": "none", "name": "TMP, U2MP, U3MP, UMP, dU3MP, dUMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:46322", "map_id": "CHEBI:46322", "name": "CHEBI:46322", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500415", "map_id": "none", "name": "Thy-Rib, (d)U", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10034962", "map_id": "none", "name": "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10036229", "map_id": "none", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500347", "map_id": "none", "name": "(d)CMP, TMP, (d)UMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500346", "map_id": "none", "name": "(d)C, T, (d)U", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10036247", "map_id": "none", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10036244", "map_id": "none", "name": "NT5C3 holoenzyme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q32L46", "map_id": "Q32L46", "name": "NT5C3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000033700", "map_id": "ENSBTAT00000033700", "name": "NT5C3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10065163", "map_id": "none", "name": "Hemoglobin:Haptoglobin:CD163 is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10065129", "map_id": "none", "name": "Hemoglobin:Haptoglobin:CD163", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P85521", "map_id": "P85521", "name": "CD163", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000026215", "map_id": "ENSBTAT00000026215", "name": "CD163", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10065161", "map_id": "none", "name": "Hemoglobin:Haptoglobin:CD163", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10064765", "map_id": "none", "name": "LRP1 (CD91) binds Hemopexin:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064755", "map_id": "none", "name": "HPX:Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "A0A452DI25", "map_id": "A0A452DI25", "name": "HPX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "ENSBTAT00000004635", "map_id": "ENSBTAT00000004635", "name": "HPX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064761", "map_id": "E1BGJ0", "name": "LRP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "ENSBTAT00000017556", "map_id": "ENSBTAT00000017556", "name": "LRP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10064763", "map_id": "none", "name": "LRP1:Hemopexin:heme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "E1BGJ0", "map_id": "E1BGJ0", "name": "LRP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10064753", "map_id": "none", "name": "Ferriheme is transferred from Methemoglobin to Hemopexin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10064747", "map_id": "A0A452DI25", "name": "HPX", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10064751", "map_id": "none", "name": "HPX:ferriheme b", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10064757", "map_id": "none", "name": "Hemopexin binds Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10065173", "map_id": "none", "name": "LRP1:Hemopexin:heme is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane" }, { "id": "species_10065171", "map_id": "none", "name": "LRP1:Hemopexin:heme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" } ], "links": [ { "type": "product", "sub_type": "complex_component", "source": "reaction_10087663", "target": "species_10087661" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087657", "target": "reaction_10087663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10089415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R2", "target": "species_10089422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030584", "target": "F1N0R2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030584", "target": "species_10087655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030584", "target": "species_10087674" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087795", "target": "species_10087657" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087655", "target": "reaction_10087795" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087650", "target": "species_10049902" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087648", "target": "reaction_10087650" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077926", "target": "species_10087648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077926", "target": "species_10049902" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077926", "target": "A0A3Q1LXM0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087732", "target": "species_10087730" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087728", "target": "reaction_10087732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087730" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10049904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXM0", "target": "species_10087688" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088519", "target": "species_10087655" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088517", "target": "reaction_10088519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10049914" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX29", "target": "species_10087688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064950", "target": "G3MX29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10049914" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10087688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10077631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10089527" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10089450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10089413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10092255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCX4", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015532", "target": "F1MCX4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015532", "target": "species_10049908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10049952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10077416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10077418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10077420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10049958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10049964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10087760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089527" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10089508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10050048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051756" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10051745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10092255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10052227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0D6", "target": "species_10056313" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004101", "target": "F1N0D6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004101", "target": "species_10049950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10088517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10049952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10077416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10077418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10077420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10049958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10049924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10087688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051942" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051756" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10051745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10090415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10092255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10054789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10056265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP6", "target": "species_10055931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015986", "target": "E1BCP6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015986", "target": "species_10055929" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045423", "target": "species_209789" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_374935", "target": "reaction_10045423" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_374935", "target": "reaction_10045419" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209789", "target": "reaction_10045421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_390627" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051601" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10046205" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10045772" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10083948" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10084012" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10083943" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10084014" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051653" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10051660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_10085114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_444154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_444152" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_727774" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209789", "target": "species_727737" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045416", "target": "reaction_10045423" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045416", "target": "reaction_10045419" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045416", "target": "reaction_10051307" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045416", "target": "reaction_10051283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHW6", "target": "species_10045416" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012607", "target": "E1BHW6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046151", "target": "species_9677997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046151", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046151", "target": "species_29408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10046151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10046153" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10038000" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10045421" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10081497" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035829" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034927" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033706" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10038450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10055444" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10040299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10040267" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10040254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10089985" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10082941" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069320" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069357" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069373" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049818" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076635" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075607" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10084849" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10041790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10041781" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076792" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059002" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10089952" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10090339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10089149" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10090103" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10090082" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10090198" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10091921" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10090246" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10092208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10068095" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10037022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10071659" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10037037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036959" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10037045" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10048587" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076743" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10047947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10091247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10092055" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10091515" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10073930" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10073942" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10074238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10074231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10046583" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034224" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075942" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10038457" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076001" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10085345" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075891" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077034" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077292" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077070" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077349" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075397" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10074686" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060316" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10048978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10048917" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049161" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10082058" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10048903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10048889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049007" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076833" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10091661" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10082078" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10066619" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059000" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058975" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059026" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10056383" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10056268" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10092040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10055946" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10055955" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10055958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10089703" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10043262" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10043219" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10080765" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033638" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10080747" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10068748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10078529" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10066094" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10072011" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10063368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058908" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077777" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058858" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059114" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10069435" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065378" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065381" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065383" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059141" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059094" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033833" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065687" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058871" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10084291" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10084261" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10044801" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059082" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058819" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060553" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060468" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058945" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059014" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059018" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10059021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058970" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058990" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10085826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058996" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10071241" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076974" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033962" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10057023" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060252" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060255" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10033979" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10054601" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10085323" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10072426" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10086557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065794" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083211" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060600" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060535" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10082152" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10082155" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060590" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060514" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083800" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060588" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060558" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060574" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060483" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10040129" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10065944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035619" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10088019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049243" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049262" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10051143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10039749" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10040645" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10072557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053258" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076172" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10053143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10071254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061064" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060938" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061134" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061061" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061014" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061046" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10044666" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10074493" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10046707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10074360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10070728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10057832" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058469" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10071924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035464" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10088571" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036256" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077496" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076475" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10075404" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10077734" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10076274" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10058755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10071763" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10049230" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035007" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10060983" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10063018" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10063020" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061084" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061006" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10061076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083544" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10083547" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036001" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034971" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035038" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034953" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035009" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10035011" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036258" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10034962" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036229" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29356", "target": "reaction_10036247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10046151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10046153" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10038000" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041284" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10045421" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10044151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10076847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064482" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064503" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064565" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064506" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10083389" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10044211" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071668" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10056702" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10056757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10048910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10076389" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043933" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10054404" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10066619" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10053361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10053363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10047907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041193" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10077751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041500" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10044232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043971" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10040636" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10056408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090468" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090470" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090472" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10033944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090460" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090708" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10089048" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10089058" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10060264" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10083204" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10052027" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10033969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10033988" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10057070" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090506" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090508" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090510" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10043910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041664" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10040881" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041486" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10081988" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10041097" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090392" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090394" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090384" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10064491" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090377" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090396" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10090382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10038060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10071715" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29368", "target": "reaction_10059181" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159362", "target": "reaction_10046151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159362", "target": "reaction_10088657" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_10046199" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_10091554" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_10047220" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_444154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_444152" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_727774" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159362", "target": "species_727737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159362", "target": "reaction_10038340" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29408", "target": "reaction_10092040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29408", "target": "reaction_10067744" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29408", "target": "reaction_10072571" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037997", "target": "reaction_10046151" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037997", "target": "reaction_10046153" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037997", "target": "reaction_10038000" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037997", "target": "reaction_10045421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21398", "target": "species_10037997" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021570", "target": "P21398" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10037997" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10051980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10051973" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10036038" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10036042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10036021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10036023" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10036220" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10076806" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10047030" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10047039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10076456" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10088864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10066616" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10056405" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10067728" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10034163" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10064343" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10078572" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10078582" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113596", "target": "reaction_10033797" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10033794" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10040878" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10041223" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10040660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10044521" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10044530" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113596", "target": "species_10086466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046153", "target": "species_9677992" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046153", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046153", "target": "species_29408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8954997", "target": "reaction_10046153" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088657", "target": "species_8954997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088657", "target": "species_71285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10088657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10078701" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10091458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10077883" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10071579" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10086319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10086286" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10077744" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10071643" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10072655" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10086033" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10044851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10034004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10039930" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10038238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10076898" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71284", "target": "reaction_10076900" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088654", "target": "reaction_10088657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003905", "target": "species_10088654" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046552", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046552", "target": "species_380593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046552", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10046552" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10089795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10050437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10036029" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10036027" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10036040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10036012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10036025" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10076459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10081339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10088666" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10051989" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10051185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10035374" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10035363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10034215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113526", "target": "reaction_10075350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_380598", "target": "reaction_10046552" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041397" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041412" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10036029" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10036027" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10036040" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10036012" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10036025" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113529", "target": "species_10046076" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113529", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113529", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10038895" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10038647" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041337" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041345" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10044225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10067731" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10067375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10060361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10051185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10051165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10077444" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113529", "target": "species_10065958" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113529", "target": "species_10084765" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10066289" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10035374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041104" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10041325" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10040682" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10035363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113529", "target": "reaction_10058772" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10036029" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10036027" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10036040" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10036012" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10036025" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10038895" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10051185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10077444" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10035374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29362", "target": "reaction_10035363" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034212", "target": "reaction_10046552" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034212", "target": "reaction_10034215" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20000", "target": "species_10034212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011521", "target": "P20000" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038000", "target": "species_500604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038000", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038000", "target": "species_29408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209914", "target": "reaction_10038000" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10091927" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10047254" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10045784" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209914", "target": "reaction_10043917" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10054315" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_10091518" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_444154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_444152" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_727774" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209914", "target": "species_727737" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078658", "target": "species_10078656" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078654", "target": "reaction_10078658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4H7", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4H7", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087280", "target": "A0A3Q1N4H7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5L7", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5L7", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071934", "target": "A0A3Q1M5L7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJH0", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJH0", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016027", "target": "E1BJH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC01", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC01", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024009", "target": "Q3ZC01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB47", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB47", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004955", "target": "A7MB47" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS1", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS1", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019836", "target": "E1BCS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR51", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR51", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023088", "target": "A6QR51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME75", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME75", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075104", "target": "A0A3Q1ME75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHL0", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHL0", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010879", "target": "E1BHL0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N546", "target": "species_10078654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N546", "target": "species_10078656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071100", "target": "A0A3Q1N546" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078604", "target": "reaction_10078658" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020860", "target": "species_10078604" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020860", "target": "F1MNK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNK6", "target": "species_10078656" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081380", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081380", "target": "species_10081373" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10081380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087621" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073831" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10050254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10065517" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10050922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10081490" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073047" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10034927" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036607" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10055444" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043129" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10084466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10077807" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040933" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10082045" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10042961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061469" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057139" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083483" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057700" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061492" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056168" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056170" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056205" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056199" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089597" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089615" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10050428" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089251" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087726" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087783" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087766" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089321" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089329" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087763" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089267" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051949" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051936" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051954" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089530" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089523" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089427" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089453" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089516" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10089511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051771" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051774" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10051748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10034944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073152" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073234" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073145" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073011" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10084096" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10063353" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091175" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10043441" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10061166" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10043459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10073543" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10073517" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10073523" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10073505" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10083329" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10092201" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10092205" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10068707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041640" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041647" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041637" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070931" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041604" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10037004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10063317" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10063305" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10063338" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10063534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10086682" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10086684" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091156" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10045978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10088940" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039667" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10048660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074088" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074137" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074129" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074176" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10075916" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10075205" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10075239" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090954" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090949" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039601" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090666" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057318" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040779" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040782" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073237" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073166" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073028" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072927" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040776" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040788" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040785" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072976" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073127" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040794" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040791" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073097" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073090" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073228" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073102" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072920" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057850" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10058474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057862" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070651" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070589" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070615" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069535" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070645" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070624" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057166" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057184" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10084080" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040286" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040289" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10044470" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083565" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083632" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083652" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083690" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083588" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10083707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090428" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090501" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039209" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039200" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039155" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085101" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087848" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087852" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10077897" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071566" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074686" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052471" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060309" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10048896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049154" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049141" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091941" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10084185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10084190" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10067950" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10068020" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091661" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10058785" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066401" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10081346" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041817" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085352" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053352" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053348" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041753" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041756" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041744" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_30595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_170037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10073708" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057836" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10054791" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090844" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10092159" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10092173" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10092043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052147" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052233" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052236" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10052229" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056315" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056283" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10056287" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10089693" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_8983696" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047530" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046932" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043244" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043212" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10043270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10055451" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10055431" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10033629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10033561" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10033570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039887" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039890" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10088744" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10088898" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091779" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10091777" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10033746" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10091067" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10060771" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066168" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066059" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066127" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066147" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066120" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066144" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066052" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066102" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072383" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072388" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072045" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10072022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10067231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10067233" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10067223" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10065402" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10065407" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066345" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10065095" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041335" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041357" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041347" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047659" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047763" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047753" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047735" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049024" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069226" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069221" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10069121" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071603" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071636" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10047200" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10047177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10059063" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10077758" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10059150" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060537" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071171" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071313" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10071125" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10066786" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10055645" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10037604" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10086587" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10040955" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085313" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10083331" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090172" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10090175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087455" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10042847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10042838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10087487" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060476" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060569" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060572" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10085780" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060429" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060461" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060579" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060501" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060518" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060614" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060597" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060516" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10039041" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10038347" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041321" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041317" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10041319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10037517" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_8936166" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053258" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10076172" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10076179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070689" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10044666" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074493" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10046707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10058216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10074360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10070728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10057832" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10058469" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10037723" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10037702" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10071924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10044039" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10053044" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10034231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10039865" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035345" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035329" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10034989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035020" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10088624" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10034980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061116" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060956" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061011" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061079" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061034" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061024" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10061125" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10060917" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036306" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10050366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10049351" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10044634" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113592", "target": "species_10044619" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035038" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10035029" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036692" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036683" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113592", "target": "reaction_10036685" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081359", "target": "reaction_10081380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10081359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10081373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXL7", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054559", "target": "A0A3Q1LXL7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10081359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10081373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL3", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053056", "target": "E1BCL3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053056", "target": "F1MTV9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053056", "target": "A0A3Q1LR94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10081359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10081373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTV9", "target": "species_10051457" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10081359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10081373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR94", "target": "species_10051457" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10049067" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10083335" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10045822" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10046223" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10067952" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_170037" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10033629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10076815" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10033561" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071626" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071624" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071613" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071615" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071232" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10071195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10073838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10038660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10047472" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_8851092" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10036238" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10036231" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_10044615" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_6790050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10035698" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10035029" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10036692" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10036683" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_6788782" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29370", "target": "species_6788801" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29370", "target": "reaction_10036229" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081377", "target": "reaction_10081380" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022307", "target": "species_10081377" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081499", "target": "species_10037650" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037648", "target": "reaction_10081499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012154", "target": "species_10037648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012154", "target": "Q0VC36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10037650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10037670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10037672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10072612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10091025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC36", "target": "species_10091027" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078349", "target": "species_10078347" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077951", "target": "reaction_10078349" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077951", "target": "reaction_10077955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033450", "target": "species_10077951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033450", "target": "Q3ZBN6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078345", "target": "reaction_10078349" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044590", "target": "species_10078345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044590", "target": "Q2TA06" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044590", "target": "species_10084086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA06", "target": "species_10078347" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA06", "target": "species_10084088" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA06", "target": "species_10084100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA06", "target": "species_10084203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBN6", "target": "species_10078347" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBN6", "target": "species_10077953" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077955", "target": "species_10077953" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039892", "target": "reaction_10077955" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039892", "target": "reaction_10071607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10039892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10077953" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10071636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW4", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007967", "target": "Q3ZBW4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088542", "target": "species_10088540" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088530", "target": "reaction_10088542" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088530", "target": "reaction_10088534" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022518", "target": "species_10088530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022518", "target": "A0A452DIR4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088538", "target": "reaction_10088542" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088538", "target": "reaction_10088546" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086675", "target": "species_10088538" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086675", "target": "A0A3Q1M173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M173", "target": "species_10088540" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M173", "target": "species_10088544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR4", "target": "species_10088540" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR4", "target": "species_10088532" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088546", "target": "species_10088544" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088534", "target": "species_10088532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041386", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041386", "target": "species_194037" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041386", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193055", "target": "reaction_10041386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193055", "target": "reaction_10041293" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193055", "target": "species_1449707" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193055", "target": "species_10057878" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193055", "target": "species_10065861" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10051676" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041684" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10050650" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10092062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10092065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041284" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10034240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10050437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10044151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10034921" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10077826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064482" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064503" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064445" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10064465" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10083389" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10044985" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071691" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10072225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10044211" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071668" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10043698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10043717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10080789" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10048910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10054393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10066247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10092306" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041831" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10066574" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10066502" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10048567" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10033611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10072825" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10073438" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10073431" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10052013" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10051999" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10077904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10056531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10035812" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041193" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041353" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041349" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041351" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10077751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10057062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041500" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10044232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10043964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10043971" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10051325" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10034166" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10067398" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10090708" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10049628" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10049871" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10085896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10033969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10077453" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10066270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10066034" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10090498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10058792" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10043910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10040922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041664" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10040881" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10040904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041486" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10081988" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10081990" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041097" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041373" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041377" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041170" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041111" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10041197" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10053210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10058751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10038060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071712" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10071715" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10047065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10059181" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70106", "target": "reaction_10051215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10051676" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041684" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10050650" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10092062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10092065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041284" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10044151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10077826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10069498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064482" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064503" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064445" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10064465" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10073755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10073731" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071691" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10072225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10044211" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071668" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10080789" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10048910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10054393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10066247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10092306" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10066574" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10066502" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10072825" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10073438" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10073431" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10077921" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10047907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041193" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041353" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041349" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041351" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10077751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041500" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10044232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10043964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10043971" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10040636" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10056408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10034166" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10090708" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10033969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10077453" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10090498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10043910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10040922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041664" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10040881" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10040904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041486" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10081988" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10081990" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041097" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041373" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041377" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041170" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041111" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10041197" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10086550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10038060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071712" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10071715" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10047065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29364", "target": "reaction_10051215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10076281" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10084679" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10041424" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10046968" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10082078" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10033592" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10034013" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10035579" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10090474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10090386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10090462" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10090464" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29366", "target": "reaction_10076133" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041383", "target": "reaction_10041386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041383", "target": "reaction_10041395" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007353", "target": "species_10041383" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041393", "target": "species_193982" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041393", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041393", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194012", "target": "reaction_10041393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041397" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041412" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10038647" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10069948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041337" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041345" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113533", "target": "species_10057046" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10044225" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113533", "target": "species_10089046" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113533", "target": "species_10089056" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10060216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10060250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041104" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113533", "target": "reaction_10041325" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113533", "target": "species_10065129" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113533", "target": "species_10065161" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041397" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041412" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10050437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041337" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041359" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041345" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10044225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10067731" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10051165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041104" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113600", "target": "reaction_10041325" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193982", "target": "species_1449707" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193982", "target": "species_10057878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10077113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10050446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10089808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10082068" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113563", "target": "species_10033589" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10041172" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113563", "target": "reaction_10041327" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10089728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10033868" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10076984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10075631" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10050169" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10082068" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10076485" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10081349" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10051989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10033755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10065328" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10076994" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10088526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10058983" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10058934" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10076891" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10060216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10060250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10078575" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10033806" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10076785" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10066416" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10046698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10034215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10058774" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10082948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113521", "target": "reaction_10036267" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041390", "target": "reaction_10041393" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041390", "target": "reaction_10041397" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041390", "target": "reaction_10041415" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055451", "target": "species_10041390" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055451", "target": "F1MG97" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055451", "target": "F1MWH3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041269", "target": "species_193055" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196344", "target": "reaction_10041269" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041253", "target": "reaction_10041269" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041253", "target": "reaction_10041719" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041253", "target": "reaction_10041295" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041253", "target": "reaction_10041721" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041253", "target": "reaction_10041379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P14893", "target": "species_10041253" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087114", "target": "P14893" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041267", "target": "reaction_10041269" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041267", "target": "reaction_10047362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10041267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10077694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10077703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10047350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10047352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10047360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10045702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10043954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01217", "target": "species_10045742" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078886", "target": "P01217" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078886", "target": "species_10041260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04651", "target": "species_10041267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04651", "target": "species_10077694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04651", "target": "species_10077703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04651", "target": "species_10047360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04651", "target": "species_10045742" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057054", "target": "P04651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057054", "target": "species_10045740" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057054", "target": "species_10041265" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041397", "target": "species_194012" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041397", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041397", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194005", "target": "reaction_10041397" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041719", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041719", "target": "species_196344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041719", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193103", "target": "reaction_10041719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193103", "target": "reaction_10041284" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193103", "target": "reaction_10040112" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041295" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041721" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10033671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10064584" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10068078" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10071673" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10076840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10071659" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10071678" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10071648" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10082058" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10076151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10076833" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041817" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10086623" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10033611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10083115" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29360", "target": "species_10033576" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10065597" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29360", "target": "species_10033830" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10054620" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041502" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041484" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10041204" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10039749" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10090458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10064500" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10090440" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10034175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10034206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10076144" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29360", "target": "reaction_10035319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10034240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10043698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10043717" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10033611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10035812" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73473", "target": "reaction_10081968" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041415", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041415", "target": "species_194005" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041415", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193988", "target": "reaction_10041415" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193988", "target": "species_1449707" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193988", "target": "species_10057878" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076281", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076281", "target": "species_193066" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076281", "target": "species_29364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193132", "target": "reaction_10076281" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193132", "target": "reaction_10044232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193066", "target": "reaction_10051676" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076278", "target": "reaction_10076281" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008272", "target": "species_10076278" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077113", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077113", "target": "species_5696848" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077113", "target": "species_113600" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696835", "target": "reaction_10077113" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077110", "target": "reaction_10077113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002073", "target": "species_10077110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002073", "target": "F1N678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041277", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041277", "target": "species_193066" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041277", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041277", "target": "species_29460" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193079", "target": "reaction_10041277" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_444074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29460", "target": "species_10046142" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041274", "target": "reaction_10041277" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041274", "target": "reaction_10041299" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019823", "target": "species_10041274" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051676", "target": "species_193132" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051676", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051673", "target": "reaction_10051676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQD0", "target": "species_10051673" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064720", "target": "Q1JQD0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041299", "target": "species_193132" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041299", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041299", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041299", "target": "species_29460" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193057", "target": "reaction_10041299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193057", "target": "reaction_10050650" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193057", "target": "reaction_10092062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193057", "target": "reaction_10092065" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084679", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084679", "target": "species_193066" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084679", "target": "species_29364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176619", "target": "reaction_10084679" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176619", "target": "reaction_10040115" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10084676", "target": "reaction_10084679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004193", "target": "species_10084676" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041692", "target": "species_193156" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10041692", "target": "species_10041688" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041690", "target": "reaction_10041692" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28918", "target": "species_10041690" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047426", "target": "Q28918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047426", "target": "species_10041688" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193840", "target": "species_10041690" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193840", "target": "species_10041714" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193840", "target": "reaction_10041206" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193840", "target": "species_10085992" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193840", "target": "species_10086000" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041688", "target": "reaction_10041716" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041716", "target": "species_10041712" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041716", "target": "species_10041690" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041714", "target": "reaction_10041716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKK4", "target": "species_10041714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKK4", "target": "species_10041712" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015578", "target": "E1BKK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCL2", "target": "species_10041714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCL2", "target": "species_10041712" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057451", "target": "Q0VCL2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041684", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041684", "target": "species_196066" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196095", "target": "reaction_10041684" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041681", "target": "reaction_10041684" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041681", "target": "reaction_10072825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Q1", "target": "species_10041681" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078546", "target": "A0A3Q1M9Q1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078546", "target": "A0A3Q1MBL5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL5", "target": "species_10041681" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041290", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041290", "target": "species_29510" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041290", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041290", "target": "species_176626" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193124", "target": "reaction_10041290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193124", "target": "reaction_10041721" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29510", "target": "reaction_10034175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176626", "target": "reaction_10041295" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176626", "target": "reaction_10040136" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041281", "target": "reaction_10041290" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041281", "target": "reaction_10041293" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041281", "target": "reaction_10041297" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041281", "target": "reaction_10041284" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074189", "target": "species_10041281" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10041290" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10050650" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10041295" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10092062" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10092065" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041288", "target": "reaction_10041412" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010386", "target": "species_10041288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010386", "target": "species_10046769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010386", "target": "P01190" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010386", "target": "species_10046737" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050650", "target": "species_469662" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050650", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050647", "target": "reaction_10050650" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020570", "target": "species_10050647" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041293", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041293", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041293", "target": "species_193092" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193092", "target": "reaction_10041297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193092", "target": "reaction_10041395" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041295", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041295", "target": "species_193079" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041295", "target": "species_73473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092062", "target": "species_469662" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092062", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10092059", "target": "reaction_10092062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004043", "target": "species_10092059" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041297", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041297", "target": "species_29510" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041297", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041297", "target": "species_193079" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092065", "target": "species_469662" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092065", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069495", "target": "reaction_10092065" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069495", "target": "reaction_10069498" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019855", "target": "species_10069495" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041284", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041284", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041284", "target": "species_193124" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041721", "target": "species_196366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041721", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041721", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196366", "target": "reaction_10041379" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057880", "target": "species_10057878" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_1449707", "target": "reaction_10057880" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_194011", "target": "species_1449707" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_194011", "target": "species_10057878" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057876", "target": "reaction_10057880" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023402", "target": "species_10057876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023402", "target": "E1BF81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF81", "target": "species_10057878" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041424", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041424", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041424", "target": "species_194035" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193977", "target": "reaction_10041424" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041421", "target": "reaction_10041424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PTG3", "target": "species_10041421" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020078", "target": "F6PTG3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041379", "target": "species_193092" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041395", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041395", "target": "species_193966" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041395", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041412", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041412", "target": "species_194011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041412", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193998", "target": "reaction_10041412" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041409", "target": "reaction_10041412" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG97", "target": "species_10041409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU47", "target": "species_10041409" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006034", "target": "F1MU47" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWH3", "target": "species_10041409" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034240", "target": "species_29708" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034240", "target": "species_29360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29398", "target": "reaction_10034240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29398", "target": "reaction_10052040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29398", "target": "reaction_10052043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29398", "target": "reaction_10052046" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29708", "target": "reaction_10033671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29708", "target": "reaction_10051314" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033668", "target": "reaction_10034240" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033668", "target": "reaction_10033671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P19858", "target": "species_10033668" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056276", "target": "P19858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4R3", "target": "species_10033668" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045699", "target": "A0A3Q1M4R3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNS9", "target": "species_10033668" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003234", "target": "E1BNS9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089721", "target": "species_10089719" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089717", "target": "reaction_10089721" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011523", "target": "species_10089717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011523", "target": "F6Q200" }, { "type": "reactant", "sub_type": "other", "source": "species_9010792", "target": "reaction_10089721" }, { "type": "inhibitor", "sub_type": "other", "source": "species_9010792", "target": "reaction_10089728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q200", "target": "species_10089719" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089728", "target": "species_904849" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089728", "target": "species_3301973" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_904849", "target": "reaction_10052056" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089725", "target": "reaction_10089728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEZ2", "target": "species_10089725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEZ2", "target": "species_10033950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEZ2", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075831", "target": "A0A3Q1MEZ2" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29450", "target": "species_10089725" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10076468" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10041955" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10064554" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10064567" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29450", "target": "species_10064471" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29450", "target": "species_10064476" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090489" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090491" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10067744" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29450", "target": "species_10033950" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10076903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090388" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10090379" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10077658" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10040021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10071717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29450", "target": "reaction_10036938" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_1655887", "target": "reaction_10089728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1655887", "target": "reaction_10060361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1655887", "target": "reaction_10067425" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076468", "target": "species_5694130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5694074", "target": "reaction_10076468" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076465", "target": "reaction_10076468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10076465" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10034181" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067905" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10071670" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10046136" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10077880" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10091456" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10090951" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10090933" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10090946" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29426", "target": "reaction_10049385" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29426", "target": "reaction_10049392" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10073474" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10058521" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10041814" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10036204" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10042912" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10053272" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10053277" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10053345" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054520" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054501" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054511" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10056333" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054785" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10054789" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10080744" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10084126" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10080753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10076127" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10078757" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10086245" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10058787" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067409" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067395" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10068573" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067385" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10067407" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10068571" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10069852" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10068713" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10073444" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10073462" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29426", "target": "reaction_10073446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29426", "target": "reaction_10049378" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10060272" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10060247" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10077121" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10040669" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10040686" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10035461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10034203" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10076141" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10075359" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10075347" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10058748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10058719" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10058769" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10071760" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10035004" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10034950" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29426", "target": "species_10034959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUZ1", "target": "species_10076465" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016884", "target": "A4FUZ1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033671", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033671", "target": "species_29398" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033671", "target": "species_73473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051980", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051980", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_880013", "target": "reaction_10051980" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113594", "target": "species_10046449" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113594", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113594", "target": "species_10046513" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10033757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10045692" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10041878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10033728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10052030" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10045036" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113594", "target": "reaction_10051198" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_31649", "target": "reaction_10036038" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_31649", "target": "reaction_10036042" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_31649", "target": "reaction_10036021" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_31649", "target": "reaction_10036023" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051977", "target": "reaction_10051980" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020226", "target": "species_10051977" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051973", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051973", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_879997", "target": "reaction_10051973" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051970", "target": "reaction_10051973" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081426", "target": "species_10051970" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_880069", "target": "reaction_10051973" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_880067", "target": "reaction_10051973" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_113527", "target": "reaction_10051973" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10050443" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10033703" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10061347" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10061345" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090617" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090635" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090642" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090628" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090685" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10090689" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10034111" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10034135" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10034099" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10059032" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10059041" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10067372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10060977" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113527", "target": "species_10060969" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033868", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033868", "target": "species_29654" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113559", "target": "reaction_10033868" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113559", "target": "reaction_10033690" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113559", "target": "reaction_10035417" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113559", "target": "reaction_10035372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113587", "target": "reaction_10033868" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113587", "target": "reaction_10089782" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113587", "target": "reaction_10077458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113587", "target": "reaction_10033757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113587", "target": "reaction_10045043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10038354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10033824" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10035417" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10038380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10050160" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29374", "target": "reaction_10040185" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033865", "target": "reaction_10033868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK1", "target": "species_10033865" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005730", "target": "Q29RK1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050446", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050446", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050446", "target": "species_113600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050446", "target": "species_29376" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29938", "target": "reaction_10050446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29376", "target": "reaction_10033912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29376", "target": "reaction_10058774" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050443", "target": "reaction_10050446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04467", "target": "species_10050443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04467", "target": "species_10075337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04467", "target": "species_10075341" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018741", "target": "Q04467" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089808", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089808", "target": "species_113557" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089808", "target": "species_113600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089808", "target": "species_29376" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113544", "target": "reaction_10089808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113544", "target": "reaction_10089795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113544", "target": "reaction_10045050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113544", "target": "reaction_10041878" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113557", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113557", "target": "species_429748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113557", "target": "species_8876310" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113557", "target": "species_8876304" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089805", "target": "reaction_10089808" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10089805" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10089792" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10089779" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10069354" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10063422" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10041796" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10036903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10047466" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10040567" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10034224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10042903" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10041808" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10053295" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10041750" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10034154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10076812" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10033547" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10033635" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10033567" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10033549" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10034038" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10033541" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067605" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067607" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067619" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067641" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068745" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067646" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067627" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068750" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10068734" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067636" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10067617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10071469" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10065356" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10065325" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10065316" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10059138" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10059079" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10059032" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060489" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10076821" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10059088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10059041" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_426219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_426221" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10057020" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10054598" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10090172" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29926", "target": "reaction_10090175" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060495" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10088577" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10035607" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10040919" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10040889" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10040910" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10083858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10083849" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10083886" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10053140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10061058" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10071921" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036253" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036226" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10044530" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036925" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10034977" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060977" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10060969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036303" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10035441" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10044615" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_6790050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10034995" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29926", "target": "species_10036244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCX7", "target": "species_10089805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000306", "target": "Q0VCX7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089795", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089795", "target": "species_113557" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089795", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089795", "target": "species_29376" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089792", "target": "reaction_10089795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWG7", "target": "species_10089792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074198", "target": "A0A3Q1MWG7" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_113588", "target": "reaction_10089795" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10089795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10033697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10033912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10042906" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10088666" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10081984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10066585" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10038354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10073838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10038660" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10051165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10038380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10046698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10050160" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10040185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10036614" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10035426" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10051075" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113593", "target": "reaction_10077890" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050437", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050437", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050437", "target": "species_29362" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050434", "target": "reaction_10050437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11024", "target": "species_10050434" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080867", "target": "P11024" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089782", "target": "species_113557" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089782", "target": "species_29376" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089779", "target": "reaction_10089782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ98", "target": "species_10089779" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046873", "target": "Q2HJ98" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073835", "target": "species_10046585" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10073835" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10046588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10049894" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10073853" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10039180" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039125", "target": "reaction_10039155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSR3", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073291", "target": "A0A3Q1LSR3" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073822" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10069253" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037315" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10065491" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039728" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090272" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090304" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090311" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073044" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10044826" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10044819" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10043580" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10043657" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10036954" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089989" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091882" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091894" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091900" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091914" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10089972" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091876" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10057191" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10083004" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083001" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082993" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082995" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10077800" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10043628" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10076584" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10076581" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10043649" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082020" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083375" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082024" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10082042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10057695" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073537" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10077603" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073159" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10087376" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10089937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092388" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090330" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090325" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089862" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089886" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10089011" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090117" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090143" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037305" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090098" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037299" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073712" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090075" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092374" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092378" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090087" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090203" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090191" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091948" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091992" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10092022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10091832" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091829" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091862" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090239" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10092002" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092000" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10092018" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073752" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073575" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072505" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073802" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073804" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073784" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073794" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073501" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073517" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073523" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073491" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10068935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10068937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073505" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10045016" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10045005" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10053213" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039640" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10088937" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10048370" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039620" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10036956" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039642" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10046534" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037544" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037546" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047821" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10064915" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089201" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10046149" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10051656" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10051653" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047464" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047466" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10089165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10048170" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047841" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047544" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10051667" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10037330" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037327" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037321" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072115" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072121" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10074038" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074065" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073898" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074213" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074144" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074153" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074225" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074229" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091591" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091593" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10091529" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090951" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090933" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10090946" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10039592" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039734" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10087367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10072993" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10087370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073136" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10072957" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10087373" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10073122" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10057857" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10040331" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10040317" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083692" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039147" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10039059" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039057" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039117" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10039123" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10038107" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10038105" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10034385" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10034903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10034383" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10034381" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10034387" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10040838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10085076" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10085237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091134" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10091141" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10040834" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10058511" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_30595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086136" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10085932" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10085915" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086097" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086090" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086209" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086196" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086019" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10085988" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10085983" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086054" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086041" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10086182" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10086169" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_170037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10090919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10056239" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10064225" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10040840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10065087" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10065092" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10037433" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10037431" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10037353" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047592" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10047458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10069208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10069144" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084234" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084236" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084286" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084252" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083720" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084244" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10091362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10091351" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10070999" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10070983" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10070995" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10070989" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10084026" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083141" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083177" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083147" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083128" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083333" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083323" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083135" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083185" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10060581" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083449" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083763" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10083765" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10049035" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10049032" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10049014" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10049011" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072423" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10072401" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072322" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072324" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10072441" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10043501" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10063558" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10035596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10046648" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10046646" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10049426" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10049420" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10047475" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_10047472" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_8936166" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_8851233" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_8851509" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29438", "target": "reaction_10036928" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29438", "target": "species_482807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG06", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003739", "target": "F1MG06" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QU5", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053181", "target": "Q17QU5" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10037313" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10040312" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090308" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10044815" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29420", "target": "reaction_10039485" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10037043" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089965" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10082997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10082034" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10043642" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10076493" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089932" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090323" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090347" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090093" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090033" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090193" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091827" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10090241" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10045007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039646" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10037355" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10089205" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10051645" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10047839" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10047953" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10072115" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10072121" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29420", "target": "reaction_10091527" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039587" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039055" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039115" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039117" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10040838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10085076" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10085237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10043519" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10040834" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10086161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_170037" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10040840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10084288" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10084254" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091333" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29420", "target": "reaction_10091336" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10091362" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10084026" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10083455" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10049028" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10072399" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10046644" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10049418" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_8851092" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_8851224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_8851462" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_8851518" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_10053041" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29420", "target": "reaction_10036928" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29420", "target": "species_482803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVT8", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075507", "target": "A0A3Q1MVT8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD29", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012331", "target": "Q0VD29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039101" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX43", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031476", "target": "Q3SX43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10074174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10039095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T132", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048084", "target": "Q3T132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10074174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10039095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QQ1", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047833", "target": "Q17QQ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10039095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2M2U3", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019980", "target": "Q2M2U3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10039095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ68", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019928", "target": "Q3SZ68" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10046585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10073822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10039123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10091338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYC8", "target": "species_10091340" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084666", "target": "A0A3Q1LYC8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084666", "target": "species_10039075" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074507", "target": "species_10074505" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074495", "target": "reaction_10074507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB94", "target": "species_10074495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB94", "target": "species_10074505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB94", "target": "species_10074399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB94", "target": "species_10074413" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083637", "target": "A7MB94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10074495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10074505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10074399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10074413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10084268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GJW7", "target": "species_10084274" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019814", "target": "Q9GJW7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10074495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10074505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10074399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10074413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10070216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10088889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10084268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O41515", "target": "species_10084274" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015449", "target": "O41515" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015449", "target": "species_10070214" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_10074495" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_10074505" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1602375", "target": "reaction_10059853" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_5696348" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_10076961" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_947594" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602375", "target": "species_947588" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052773", "target": "reaction_10074507" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10052773", "target": "reaction_10091409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U5", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U5", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U5", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U5", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U5", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018429", "target": "Q3T0U5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX42", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX42", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX42", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX42", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX42", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010436", "target": "Q3SX42" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ35", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ35", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ35", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ35", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ35", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006291", "target": "Q2HJ35" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDY3", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDY3", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDY3", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDY3", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDY3", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008352", "target": "A2VDY3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E32", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E32", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E32", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E32", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E32", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017812", "target": "Q08E32" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS7", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS7", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS7", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS7", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS7", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018071", "target": "Q58CS7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148L0", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148L0", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148L0", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148L0", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148L0", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018623", "target": "Q148L0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10052773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10091646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H704", "target": "species_10091632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017987", "target": "A6H704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017987", "target": "species_10052771" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074365", "target": "species_426639" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5676030", "target": "reaction_10074365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426639", "target": "reaction_10059000" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426639", "target": "reaction_10058975" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426639", "target": "reaction_10059026" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426639", "target": "reaction_10085340" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426639", "target": "reaction_10060476" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074362", "target": "reaction_10074365" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMW0", "target": "species_10074362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMW0", "target": "species_10060532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074360", "target": "A0A3Q1LMW0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ59", "target": "species_10074362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ59", "target": "species_10060532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084980", "target": "A0A3Q1LZ59" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074381", "target": "species_10074379" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074371", "target": "reaction_10074381" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023301", "target": "species_10074371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023301", "target": "F1MZE2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074377", "target": "reaction_10074381" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074377", "target": "reaction_10074415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10074377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10074379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10074413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10074653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10074657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA9", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077815", "target": "A0A3Q1LXA9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074379", "target": "reaction_10090398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZE2", "target": "species_10074379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZE2", "target": "species_10074653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZE2", "target": "species_10074657" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074415", "target": "species_10074413" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074399", "target": "reaction_10074415" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074142", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074142", "target": "species_10074140" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073828", "target": "reaction_10074142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH45", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH45", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH45", "target": "species_10073822" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076195", "target": "E1BH45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJE0", "target": "species_10073828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJE0", "target": "species_10074140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJE0", "target": "species_10073822" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000651", "target": "Q2HJE0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046570", "target": "reaction_10074142" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046570", "target": "reaction_10049894" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046570", "target": "reaction_10072595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_10046570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10046572" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10033629" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10033638" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_10050635" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10050637" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10033737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_10038936" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_10072593" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_500101" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10036238" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_500125" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10036907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10036001" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_500088" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_76577", "target": "reaction_10036692" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_6788778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76577", "target": "species_6788802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10046570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10042890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10042880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10038932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10038936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQV7", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024965", "target": "F1MQV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBG5", "target": "species_10046570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBG5", "target": "species_10042890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBG5", "target": "species_10042880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBG5", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBG5", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000017", "target": "F1MBG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIS9", "target": "species_10046570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIS9", "target": "species_10042890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIS9", "target": "species_10042880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIS9", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIS9", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007798", "target": "Q5BIS9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10046570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10042890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10042880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10038932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10038936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B986", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080624", "target": "E1B986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10046570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10042890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10042880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10081619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10038932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10038936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSS5", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086099", "target": "A0A3Q1MSS5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074302", "target": "species_10074300" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693050", "target": "reaction_10074302" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693050", "target": "species_10074300" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693050", "target": "species_10085782" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693050", "target": "species_10085695" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693050", "target": "species_8849958" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074298", "target": "reaction_10074302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP4", "target": "species_10074298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP4", "target": "species_10074300" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066992", "target": "A0A3Q1MUP4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ60", "target": "species_10074298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ60", "target": "species_10074300" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016002", "target": "Q2KJ60" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090398", "target": "species_10074653" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074653", "target": "reaction_10074659" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074659", "target": "species_10074657" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074655", "target": "reaction_10074659" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083652", "target": "species_10074655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083652", "target": "A4FUE9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE9", "target": "species_10074657" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10070265", "target": "species_10070263" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070226", "target": "reaction_10070265" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070226", "target": "reaction_10070261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029455", "target": "species_10070226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029455", "target": "species_10070263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029455", "target": "species_10070224" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029455", "target": "species_10070222" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070218", "target": "species_10070216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070214", "target": "reaction_10070218" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070214", "target": "reaction_10088891" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070210", "target": "reaction_10070218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D7GLD0", "target": "species_10070210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D7GLD0", "target": "species_10070216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D7GLD0", "target": "species_10055843" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D7GLD0", "target": "species_10055845" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080672", "target": "D7GLD0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10070210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10070216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10051091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10051093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10043729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVE4", "target": "species_10043737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075019", "target": "A0A3Q1LVE4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075019", "target": "species_10043723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE3", "target": "species_10070210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE3", "target": "species_10070216" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001994", "target": "Q1LZE3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPL1", "target": "species_10070210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPL1", "target": "species_10070216" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013860", "target": "F1MPL1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10070259", "target": "species_10070226" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070224", "target": "reaction_10070259" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070256", "target": "reaction_10070259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPI6", "target": "species_10070256" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013405", "target": "A6QPI6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI08", "target": "species_10070256" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070920", "target": "Q2KI08" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZB5", "target": "species_10070256" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032251", "target": "Q1LZB5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E34", "target": "species_10070256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E34", "target": "species_10092316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019001", "target": "Q08E34" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019001", "target": "species_10070254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8YXZ8", "target": "species_10070256" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046547", "target": "A8YXZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7B1", "target": "species_10070256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7B1", "target": "species_10077171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7B1", "target": "species_10077189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000733", "target": "A6H7B1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JY4", "target": "species_10070256" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011817", "target": "Q56JY4" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10070261", "target": "species_10070222" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088891", "target": "species_10088889" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087624", "target": "reaction_10088891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002144", "target": "species_10087624" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002144", "target": "F1N5S9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002144", "target": "species_10087608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002144", "target": "species_10087605" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002144", "target": "species_10087618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5S9", "target": "species_10088889" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087615", "target": "species_10087605" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087608", "target": "reaction_10087615" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087608", "target": "reaction_10087621" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10087612", "target": "reaction_10087615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009887", "target": "species_10087612" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087621", "target": "species_10087618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087621", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040957", "target": "reaction_10087621" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040957", "target": "reaction_10070596" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040957", "target": "reaction_10040961" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040957", "target": "reaction_10047985" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10040957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "E1BIM8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10088935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10090411" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10040307" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10057248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011767", "target": "species_10047983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073831", "target": "species_10073828" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073831", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073822", "target": "reaction_10073831" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050514", "target": "species_10050512" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_210382", "target": "reaction_10050514" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10050512" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_210382", "target": "reaction_10045138" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_210382", "target": "reaction_10044076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_210382", "target": "reaction_10044086" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_210382", "target": "reaction_10051085" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_10051083" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_428027" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_210382", "target": "species_427997" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050510", "target": "reaction_10050514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE57", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE57", "target": "species_10050512" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070796", "target": "A2VE57" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_10050486" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_10051083" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_8941540" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352022", "target": "species_8941541" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10048618" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10091583" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10066206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10066227" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10066199" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352022", "target": "reaction_10065991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJD2", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJD2", "target": "species_10050512" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015567", "target": "Q2HJD2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y0", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y0", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y0", "target": "species_10050486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y0", "target": "species_10051083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073656", "target": "A0A3Q1M9Y0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10073804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10083783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10083787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM66", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003326", "target": "F1MM66" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003326", "target": "species_10050472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10051060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10069445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10037002" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10069454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10036972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10036978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10049470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10049475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10091060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10091064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10091073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10048785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR28", "target": "species_10060914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044622", "target": "A0A3Q1MR28" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044622", "target": "species_10037000" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044622", "target": "species_10077737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10083783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10083787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH0", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084144", "target": "A0A3Q1MBH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61602", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61602", "target": "species_10050512" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068404", "target": "P61602" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFJ1", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFJ1", "target": "species_10050512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFJ1", "target": "species_10083783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFJ1", "target": "species_10083787" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077778", "target": "A0A3Q1MFJ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCW8", "target": "species_10050510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCW8", "target": "species_10050512" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022788", "target": "F1MCW8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050512", "target": "reaction_10050517" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050517", "target": "species_74016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10050517" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10092050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10067332" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10054318" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10091521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10051521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10051498" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10037915" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10037887" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10037895" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10037607" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74112", "target": "reaction_10065866" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10086333" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10059844" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10058967" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10069445" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037002" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10069454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10036972" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10036978" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10049470" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10049475" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10045013" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037577" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10045986" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10040486" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10070628" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10070626" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10038217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10038215" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037829" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037843" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10038219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060038" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10048504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10048526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10048533" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10058905" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10056380" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060622" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060028" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10064388" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10091060" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10091064" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10091073" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10039776" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10078755" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10078757" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10081555" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10081557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10059808" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10084704" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10086245" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10047196" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10047177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10048787" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10048785" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10047893" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060489" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10047900" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10071344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037807" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037910" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037884" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037893" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_426219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_426221" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10091583" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10066206" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10066227" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10066021" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10065991" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060495" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10035594" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10035590" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10035619" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10065940" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10083858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10083849" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10083870" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10083886" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10083923" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74016", "target": "reaction_10053143" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037795" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037798" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037785" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037850" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037921" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037945" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037835" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10037813" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10076853" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10076881" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10061110" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10061003" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10060914" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74016", "target": "species_10061073" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045419", "target": "species_209789" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045421", "target": "species_5279533" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045421", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045421", "target": "species_29408" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039481", "target": "species_10039475" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10039481" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10051095" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10043302" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10066141" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10066180" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039473", "target": "reaction_10072053" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021630", "target": "species_10039473" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021630", "target": "Q3ZCC3" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039469", "target": "reaction_10039481" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018325", "target": "species_10039469" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018325", "target": "E1B847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B847", "target": "species_10039475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10039475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10051093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10043761" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10075996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10075998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10085342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10075966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10075968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10043289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10066165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10066139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10066178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10072049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC3", "target": "species_10072051" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039479", "target": "reaction_10039481" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020029", "target": "species_10039479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020029", "target": "Q3SX05" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050256", "target": "species_10039505" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039518", "target": "reaction_10050256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWJ8", "target": "species_10039518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWJ8", "target": "species_10039505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWJ8", "target": "species_10074745" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087439", "target": "A0A3Q1LWJ8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087439", "target": "species_10037699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087439", "target": "species_10039514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087439", "target": "species_10039497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJU7", "target": "species_10039518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJU7", "target": "species_10039505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082454", "target": "A0A3Q1LJU7" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039505", "target": "reaction_10039508" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042826", "target": "species_113550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042826", "target": "species_10042805" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10042826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10043488" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10055967" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10076112" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10076198" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075902" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10077393" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10077331" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075561" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10077317" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10068699" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10068844" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10068725" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10066966" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10089640" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10070705" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10069491" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10065760" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10065763" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10071208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075304" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10075319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10088006" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10076339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10082934" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10077016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10066684" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10072883" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10074739" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113518", "target": "reaction_10035047" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041947", "target": "reaction_10042826" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041947", "target": "reaction_10043488" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041947", "target": "reaction_10041950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ4", "target": "species_10041947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ4", "target": "species_10042805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ4", "target": "species_10084389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ4", "target": "species_10084391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001347", "target": "A5PKJ4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001347", "target": "species_10041913" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001347", "target": "species_10041915" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042823", "target": "reaction_10042826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1S8", "target": "species_10042823" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007277", "target": "F1N1S8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043488", "target": "species_113550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043488", "target": "species_10042805" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043479", "target": "reaction_10043488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9T7", "target": "species_10043479" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9T7", "target": "species_10043486" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078874", "target": "Q2T9T7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM08", "target": "species_10043479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061049", "target": "F1MM08" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS1", "target": "species_10043479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029212", "target": "A6QLS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ36", "target": "species_10043479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006022", "target": "Q2KJ36" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10043486", "target": "reaction_10043488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2YDN8", "target": "species_10043486" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007054", "target": "Q2YDN8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041950", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041950", "target": "species_10041945" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10041950" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10039508" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10050192" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10050231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10090409" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10083672" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10036981" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10049478" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10075223" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076229" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10081274" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10080457" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061049" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061017" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061128" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061131" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061052" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061119" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061137" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10060993" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10061031" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10060951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10042915" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10089610" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10065201" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10064733" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10065572" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10033535" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10050085" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10071640" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10071630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10066712" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10081595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10081629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10066704" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10080722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10066870" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10081622" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10078731" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10078720" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10081602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10068008" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10066873" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10066857" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10075181" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10056616" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10056602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074695" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074798" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10083092" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10088872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10073275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074558" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074736" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074677" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076332" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076303" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10074720" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10075173" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10076312" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10075295" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29358", "target": "reaction_10050378" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041927", "target": "reaction_10041950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLN6", "target": "species_10041927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLN6", "target": "species_10041945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLN6", "target": "species_10090537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLN6", "target": "species_10090545" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073341", "target": "A0A3Q1MLN6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNQ6", "target": "species_10041927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNQ6", "target": "species_10041945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNQ6", "target": "species_10090537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNQ6", "target": "species_10090545" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080174", "target": "A0A3Q1LNQ6" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113582", "target": "reaction_10071767" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113582", "target": "reaction_10071765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050208", "target": "species_10050206" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039493", "target": "reaction_10050208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005279", "target": "species_10039493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005279", "target": "Q08DH1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005279", "target": "species_10039489" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050204", "target": "reaction_10050208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005660", "target": "species_10050204" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005660", "target": "O77628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77628", "target": "species_10050206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH1", "target": "species_10050206" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039508", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039508", "target": "species_10039493" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039489", "target": "reaction_10039508" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050218", "target": "species_10050216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050214", "target": "reaction_10050218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081307", "target": "species_10050214" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081307", "target": "species_10050216" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081307", "target": "species_10050233" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050216", "target": "reaction_10050231" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050216", "target": "reaction_10066857" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050254", "target": "species_10050214" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050254", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050233", "target": "reaction_10050254" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050233", "target": "reaction_10066786" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050251", "target": "reaction_10050254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7Z0", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7Z0", "target": "species_10066165" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077920", "target": "E1B7Z0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7T8", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7T8", "target": "species_10066165" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082809", "target": "A0A3Q1M7T8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT51", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT51", "target": "species_10066165" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068866", "target": "A0A3Q1LT51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10033408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10083992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10084006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10083996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10052288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10039539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10039537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10064931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10043729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10043737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10043741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10043719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10043875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10053079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10075884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10092095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10055422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10033410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10066484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10057818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10077588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG53", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022919", "target": "P0CG53" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022919", "target": "species_10084119" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022919", "target": "species_10033406" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022919", "target": "species_10033404" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022919", "target": "species_10033402" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10033408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10083992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10084006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10083996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10052288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10039539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10039537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10064931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10043729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10043737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10043741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10043719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10043875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10053079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10075884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10092095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10055422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10033410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10066484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10057818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10077588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10073252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU30", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087088", "target": "A0A3Q1LU30" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087088", "target": "species_10033394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087088", "target": "species_10034499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10050251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10033408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10083992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10084006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10083996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10052288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10039539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10039537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10064931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10043729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10043737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10043741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10043719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10043875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10053079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10075884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10092095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10055422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10033410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10066484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10057818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10077588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10073252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63048", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010176", "target": "P63048" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010176", "target": "species_10084115" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010176", "target": "species_10033398" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010176", "target": "species_10034743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050192", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050192", "target": "species_10050189" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050185", "target": "reaction_10050192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M614", "target": "species_10050185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M614", "target": "species_10050189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M614", "target": "species_10050194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M614", "target": "species_10050228" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084476", "target": "A0A3Q1M614" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084476", "target": "species_10040546" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084476", "target": "species_10040551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050228" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10040565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10040567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10050082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10066867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10066855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X793", "target": "species_10066853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022358", "target": "G3X793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050228" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10040565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10040567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10050082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10066867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10066855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTT9", "target": "species_10066853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073013", "target": "A0A3Q1LTT9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073013", "target": "species_10049037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073013", "target": "species_10040563" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050189", "target": "reaction_10050196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050196", "target": "species_10050194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050231", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050231", "target": "species_10050185" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050228", "target": "reaction_10050231" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069253", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069253", "target": "species_10037315" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10069253" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10089011" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10089860" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10041470" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10037330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037313", "target": "reaction_10069144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10037313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10037315" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10089862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10089886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10089858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10072505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10072513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10068935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10068937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10043313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10047839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10047841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10083692" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10075966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10075968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10049418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61585", "target": "species_10049420" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005600", "target": "P61585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005600", "target": "species_10037311" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10089930" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10089149" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10089890" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10073577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10073549" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037315", "target": "reaction_10083697" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069250", "target": "reaction_10069253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10057859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10043788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10046901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB57", "target": "species_10069150" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070883", "target": "A7MB57" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10061489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10088937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10090720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10090724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10070580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10070586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10071501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10070638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10070640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10057250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10084375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10043788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10046901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10047884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10086579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10040945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10040952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM8", "target": "species_10040965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10052269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10052292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10057859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10070672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10070674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10070619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10070621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10043788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046820" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10046901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10072380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10047453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10037465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10037504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10037514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNB0", "target": "species_10050628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015730", "target": "A0JNB0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015730", "target": "species_10037459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10057859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10089837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10090415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10092255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10043788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10046901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10072380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10037465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10037504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10037514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N261", "target": "species_10050628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075171", "target": "F1N261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075171", "target": "species_10066117" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075171", "target": "species_10065617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075171", "target": "species_10037463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10068993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY0", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033972", "target": "A6QLY0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10068993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC64", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004007", "target": "Q3ZC64" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10068993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R05", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080646", "target": "Q17R05" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10068993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J8", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053096", "target": "A5D7J8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10068993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N163", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026958", "target": "F1N163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6H6", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033263", "target": "F1N6H6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTB6", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067384", "target": "A0A3Q1MTB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS9", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008955", "target": "E1BJS9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR1", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037789", "target": "F1MKR1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER5", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013238", "target": "E1BER5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA9", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083978", "target": "A0A3Q1MAA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJW2", "target": "species_10069118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075696", "target": "A0A3Q1MJW2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DA6", "target": "species_10069250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DA6", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DA6", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011773", "target": "Q08DA6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077455", "target": "species_10077416" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077414", "target": "reaction_10077455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076709", "target": "species_10077414" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076709", "target": "E1BAT3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049952", "target": "reaction_10077455" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077416", "target": "reaction_10077424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAT3", "target": "species_10077416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAT3", "target": "species_10077418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAT3", "target": "species_10077420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077422", "target": "species_10077420" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049956", "target": "reaction_10077422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023595", "target": "species_10049956" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023595", "target": "E1BD36" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023595", "target": "species_10056106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077418", "target": "reaction_10077422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N366", "target": "species_10077418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N366", "target": "species_10077420" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021515", "target": "F1N366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021515", "target": "species_10077410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10077420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10049958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10056196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10089313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10089319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10089325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10089327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10089323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD36", "target": "species_10087760" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077424", "target": "species_10077418" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077410", "target": "reaction_10077424" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065517", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065517", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10065517" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10036570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10057700" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073234" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10065099" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10036959" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10047498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10041851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073237" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10073228" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10057872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10070645" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10057184" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10090428" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10046932" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10043241" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10043262" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10043244" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10065894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10066144" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10066094" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10072011" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10060595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10060550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10049395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10037557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10061113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179856", "target": "reaction_10061006" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10036588" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10036604" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10036596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10036590" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10036598" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10072941" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10072946" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10065227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091252" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091257" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10043315" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043313" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10072922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10072933" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10072904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10072931" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10072937" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10070647" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10070649" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10081899" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10081901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10081903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_5620974" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10091427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10046940" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10043219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043180" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043295" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043281" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043267" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043272" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_202277" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043293" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043287" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10043289" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10066065" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066076" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10066099" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_179838", "target": "reaction_10060514" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_8849959" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_8874484" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_8874460" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_179838", "target": "species_10072328" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065514", "target": "reaction_10065517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10092255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10092149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10072390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10072360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10072362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10072385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHG9", "target": "species_10050628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075168", "target": "A0A3Q1MHG9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075168", "target": "species_10037584" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075168", "target": "species_10050626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI53", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074586", "target": "F1MI53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAW3", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAW3", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAW3", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070846", "target": "A0A3Q1NAW3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A2Z2AM52", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080723", "target": "A0A2Z2AM52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3R3B5", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077363", "target": "A3R3B5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077363", "target": "A3R3B4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7L0", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075285", "target": "A0A3Q1M7L0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4Q0", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031648", "target": "A8E4Q0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NM98", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071353", "target": "A0A3Q1NM98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHY4", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006472", "target": "F1MHY4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3R3B4", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPK9", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055860", "target": "F1MPK9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8B5", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037859", "target": "A0A140T8B5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4Y9", "target": "species_10065514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068807", "target": "A0A3Q1N4Y9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU93", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086688", "target": "A0A3Q1MU93" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01888", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016359", "target": "P01888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10035523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10035525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10057697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10041848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10070640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10057181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10065275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10092163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10046929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10043191" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32871", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072391", "target": "P32871" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072391", "target": "species_10035515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10035523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10035525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10041848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10070640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10043191" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYM3", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009083", "target": "F1MYM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10065514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10035523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10035525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10041848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10070640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10043191" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23726", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003033", "target": "P23726" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065491", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065491", "target": "species_10039728" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10065491" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073044" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10057191" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10057695" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073159" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073019" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10087376" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10091271" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10064915" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10074038" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10091529" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073182" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10087367" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10072993" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10087370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073136" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10072957" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10087373" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10073122" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10057857" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10040331" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10040317" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10090919" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10056239" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040312", "target": "reaction_10047458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10040312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10039728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10039726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10073898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074213" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10091593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10039734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB7", "target": "species_10069432" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071009", "target": "A0A3Q1LKB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10040312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10039728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10039726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10073898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074213" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10039734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R9", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012897", "target": "A5D7R9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039728", "target": "reaction_10073904" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039728", "target": "reaction_10074146" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039728", "target": "reaction_10091534" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039728", "target": "reaction_10091580" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039728", "target": "reaction_10039736" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065488", "target": "reaction_10065491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10065488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10057170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10057172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10086413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10057134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10057136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10075061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10035534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10036626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10084324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10065486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIE2", "target": "species_10066099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "Q0IIE2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10072995" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10035544" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10086408" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10050549" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10035532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10065484" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075224", "target": "species_10066149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10065488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10035491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10035505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10075061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10064912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10043817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10035534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10036626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10036624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10036628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10074033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10065486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10066099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C3", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015471", "target": "F1N7C3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015471", "target": "species_10035489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10035491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10035505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10050571" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10052269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10052292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10075061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10064912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10043817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10035534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10084324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10036554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10074033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10046940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10046820" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10065486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10066099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F9", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006216", "target": "Q3T0F9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006216", "target": "species_10035485" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040851", "target": "species_10040848" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040846", "target": "reaction_10040851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027331", "target": "species_10040846" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027331", "target": "O18968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18968", "target": "species_10040848" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049067", "target": "species_114565" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049064", "target": "reaction_10049067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013298", "target": "species_10049064" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013298", "target": "F1MUC1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10051002", "target": "species_10051000" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050998", "target": "reaction_10051002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009564", "target": "species_10050998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009564", "target": "species_10051000" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009564", "target": "G3X6N3" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051000", "target": "reaction_10052916" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050924", "target": "species_10050922" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050904", "target": "reaction_10050924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E3W2", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E3W2", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001802", "target": "A7E3W2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RS5", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RS5", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084323", "target": "Q29RS5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Q6", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Q6", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076112", "target": "A0A3Q1M5Q6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKI3", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKI3", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073296", "target": "A5PKI3" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29372", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29372", "target": "species_10050922" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10036903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10033611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10045050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10057032" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10066282" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29372", "target": "species_10039039" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10035453" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10035455" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10035479" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29372", "target": "reaction_10035481" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIU4", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIU4", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024391", "target": "A0A452DIU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE4", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE4", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080253", "target": "A0A3Q1LTE4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27967", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27967", "target": "species_10050922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27967", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27967", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002631", "target": "Q27967" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111294", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111294", "target": "species_10050922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111294", "target": "reaction_10034224" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_111294", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111294", "target": "reaction_10070735" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_111294", "target": "reaction_10035354" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H754", "target": "species_10050904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H754", "target": "species_10050922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022777", "target": "A6H754" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050994", "target": "species_10050992" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050980", "target": "reaction_10050994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10050992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10037443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10049276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTN1", "target": "species_10049504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013173", "target": "F1MTN1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10050992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10037443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10049276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ4", "target": "species_10049504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010738", "target": "F1MGZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI93", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI93", "target": "species_10050992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075662", "target": "A0A3Q1LI93" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26201", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26201", "target": "species_10050992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26201", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26201", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080828", "target": "P26201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080828", "target": "species_10049343" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10050992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10049281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044022" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHJ9", "target": "species_10044036" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086833", "target": "A0A3Q1MHJ9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086833", "target": "species_10044014" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086833", "target": "species_10044026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK28", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK28", "target": "species_10050992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067657", "target": "A5PK28" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LEU1", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LEU1", "target": "species_10050992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LEU1", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LEU1", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081148", "target": "A0A3Q1LEU1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN74", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN74", "target": "species_10050992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074339", "target": "A0A3Q1LN74" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A1L6ZA12", "target": "species_10050980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A1L6ZA12", "target": "species_10050992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087233", "target": "A0A1L6ZA12" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050948", "target": "species_10050946" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050938", "target": "reaction_10050948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZJ5", "target": "species_10050938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZJ5", "target": "species_10050946" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078091", "target": "Q8HZJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10050938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10050946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8P4", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066443", "target": "A0A3Q1N8P4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSK2", "target": "species_10050938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSK2", "target": "species_10050946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSK2", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSK2", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015829", "target": "Q9XSK2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050870", "target": "species_10050868" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050802", "target": "reaction_10050870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIX0", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIX0", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026577", "target": "A0A452DIX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17697", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17697", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17697", "target": "species_10082963" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17697", "target": "species_10082965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007324", "target": "P17697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF69", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF69", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004806", "target": "A4IF69" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY12", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY12", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY12", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY12", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016092", "target": "F1MY12" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10045330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10038157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10038196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10038145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8C8", "target": "species_10038147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053071", "target": "A0A140T8C8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053071", "target": "species_10038198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053071", "target": "species_10038203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP92", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011576", "target": "A0A0A0MP92" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4PU73", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009718", "target": "C4PU73" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MPA0", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038516", "target": "A0A0A0MPA0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1U4", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064475", "target": "G3N1U4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077453", "target": "A0A3Q1MGZ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0A0MP89", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009261", "target": "A0A0A0MP89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJK6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064935", "target": "A0A452DJK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMJ0", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMJ0", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMJ0", "target": "species_10038211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMJ0", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMJ0", "target": "species_10084063" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021638", "target": "E1BMJ0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021638", "target": "species_10091544" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021638", "target": "species_10038209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XS50", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XS50", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XS50", "target": "species_10041443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XS50", "target": "species_10041451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XS50", "target": "species_10041461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019613", "target": "Q9XS50" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019613", "target": "species_10041441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9Y5", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085713", "target": "A0A3Q1N9Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28800", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28800", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28800", "target": "species_10038326" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027793", "target": "P28800" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027793", "target": "species_10038324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34955", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072441", "target": "P34955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0A3", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063284", "target": "Q3T0A3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP91", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP91", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP91", "target": "species_10065332" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP91", "target": "species_10065334" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015925", "target": "A6QP91" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBY0", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBY0", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000051964", "target": "E1BBY0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10059866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10059801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10059728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10059699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10046674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10038260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10038326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10038272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B726", "target": "species_10038254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001674", "target": "E1B726" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001674", "target": "species_10038252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ9", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ9", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ9", "target": "species_10038298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ9", "target": "species_10038300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ9", "target": "species_10038305" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019232", "target": "A0A452DIJ9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019232", "target": "species_10038296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7J5", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7J5", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032623", "target": "G3X7J5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD83", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD83", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015874", "target": "F1MD83" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5GN72", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022991", "target": "Q5GN72" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2H1", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2H1", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067311", "target": "A0A3Q1M2H1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL4", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL4", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007016", "target": "Q17QL4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFA6", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFA6", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007913", "target": "A4IFA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10037795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10037798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0I3", "target": "species_10037813" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023573", "target": "F1N0I3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023573", "target": "species_10037817" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023573", "target": "species_10037819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPG8", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPG8", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083114", "target": "A0A3Q1LPG8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10038115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10071934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10091669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W1", "target": "species_10038174" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036726", "target": "G5E5W1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036726", "target": "species_10076686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036726", "target": "species_10071930" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036726", "target": "species_10091620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036726", "target": "species_10091628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12763", "target": "species_10079947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000673", "target": "P12763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX05", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX05", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004949", "target": "F1MX05" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKY5", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKY5", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024387", "target": "G8JKY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10034066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMG1", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083687", "target": "A0A3Q1LMG1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ33", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ33", "target": "species_10050868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009160", "target": "Q2HJ33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07455", "target": "species_10050802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07455", "target": "species_10050868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07455", "target": "species_10046619" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014713", "target": "P07455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014713", "target": "species_10046613" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051062", "target": "species_10051060" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051036", "target": "reaction_10051062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC2", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC2", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012094", "target": "F1MHC2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80513", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80513", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045083", "target": "P80513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10051060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10043441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10061166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10043459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10073543" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10073517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10073523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63258", "target": "species_10073505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008132", "target": "P63258" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRZ8", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRZ8", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012724", "target": "F1MRZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLQ7", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLQ7", "target": "species_10051060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLQ7", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLQ7", "target": "species_10049504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074863", "target": "A0A3Q1MLQ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY77", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY77", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034535", "target": "A7YY77" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10051060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10067409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10067395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10068573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10067407" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNQ4", "target": "species_10068713" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039344", "target": "F1MNQ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP13", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP13", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075491", "target": "A0A3Q1LP13" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z0", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z0", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079099", "target": "E1B8Z0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F5", "target": "species_10051036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F5", "target": "species_10051060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080925", "target": "Q5E9F5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090306", "target": "species_10090304" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090272", "target": "reaction_10090306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J5", "target": "species_10090272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J5", "target": "species_10090304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J5", "target": "species_10090308" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024876", "target": "A5D7J5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090302", "target": "reaction_10090306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWY5", "target": "species_10090302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWY5", "target": "species_10090304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWY5", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023764", "target": "F1MWY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10090302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10090304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10070672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10070674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10070619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10070621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H720", "target": "species_10069186" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069542", "target": "A6H720" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069542", "target": "species_10045210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10090264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10088960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10047654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10047612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10047614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E52", "target": "species_10069208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080749", "target": "Q08E52" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080749", "target": "species_10047644" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080749", "target": "species_10047596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ0", "target": "species_10090302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ0", "target": "species_10090304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ0", "target": "species_10090073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ0", "target": "species_10090075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086158", "target": "Q17QZ0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090311", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090311", "target": "species_10090272" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090308", "target": "reaction_10090311" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081497", "target": "species_193473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081497", "target": "species_449701" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6803743", "target": "reaction_10081497" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6803743", "target": "species_6803738" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449701", "target": "reaction_10080765" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081494", "target": "reaction_10081497" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074115", "target": "species_10081494" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050153", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050153", "target": "species_449701" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29512", "target": "reaction_10050153" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29512", "target": "reaction_10033629" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29512", "target": "reaction_10034043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10050153" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10034927" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352186" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352169" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29472", "target": "species_352088" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10052046" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10035354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10035308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29472", "target": "reaction_10035038" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10085101" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10045029" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10033716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10052013" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10051999" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10033746" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10085896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10048821" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10033788" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10054611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10087455" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10039865" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29404", "target": "reaction_10035354" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050150", "target": "reaction_10050153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZY2", "target": "species_10050150" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023441", "target": "F1MZY2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW0", "target": "species_10050150" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002867", "target": "A0A452DHW0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081490", "target": "species_6803738" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081490", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081490", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6803785", "target": "reaction_10081490" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27459", "target": "species_6803785" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1678743", "target": "species_6803785" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1678743", "target": "species_6799970" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_449703", "target": "species_6803738" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449703", "target": "reaction_10049778" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081487", "target": "reaction_10081490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF8", "target": "species_10081487" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019528", "target": "A0A452DJF8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049778", "target": "species_532204" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049775", "target": "reaction_10049778" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086526", "target": "species_10049775" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10069593", "target": "species_10069588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10069593" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10057712" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10057719" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10057735" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10068086" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10069664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10063849" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10043877" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10072138" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10074156" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10073215" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10053082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10073222" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10073208" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10073199" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10057262" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10040393" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10040447" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10040462" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10040432" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10083638" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10088787" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10092183" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10091806" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10066536" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10066551" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10089679" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10033412" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10066487" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10084206" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10084214" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033408", "target": "reaction_10076083" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069585", "target": "reaction_10069593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072372", "target": "species_10069585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072372", "target": "species_10069588" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069590", "target": "reaction_10069593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RHP0", "target": "species_10069590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RHP0", "target": "species_10069581" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032504", "target": "F6RHP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10069590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10069581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10043116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10069605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10068921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10069878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10069297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10063566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ4", "target": "species_10085114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078307", "target": "A0A3Q1MSZ4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078307", "target": "species_10043149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS5", "target": "species_10069590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS5", "target": "species_10072718" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043725", "target": "F1MLS5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043725", "target": "species_10042973" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043725", "target": "species_10088487" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069595", "target": "species_10069590" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069581", "target": "reaction_10069595" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042973", "target": "reaction_10069595" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042973", "target": "reaction_10042976" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069872", "target": "species_10069870" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069868", "target": "reaction_10069872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM1", "target": "species_10069868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM1", "target": "species_10069870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM1", "target": "species_10069892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM1", "target": "species_10069894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027911", "target": "F1MGM1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067196", "target": "reaction_10069872" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067196", "target": "reaction_10069896" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067196", "target": "reaction_10069876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026930", "target": "species_10067196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026930", "target": "E1BDG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10069870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10071326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10071328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10069894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10069874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10069878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10067086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG5", "target": "species_10085114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044480", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044480", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044480", "target": "species_571314" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10037748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10063450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10063452" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10063442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10063437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10063420" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10065216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10064511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10064531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10064516" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044235" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044255" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044158" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044280" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044218" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044223" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035865" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035861" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035977" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044265" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044204" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044167" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035911" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10035863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10061787" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044524" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113534", "target": "reaction_10044533" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10037751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10065210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10064511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10064531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10064516" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10081928" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10038427" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044235" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044255" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044158" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10048787" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044280" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044218" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044223" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035865" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035861" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035977" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044265" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044204" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044167" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035911" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10035863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044524" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156540", "target": "reaction_10044533" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_215557", "target": "reaction_10044480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063413" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063456" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063440" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10063430" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10064511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10064531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10064516" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044235" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044255" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044158" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044280" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044218" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044250" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044223" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035865" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035861" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035977" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044265" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044204" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044167" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035911" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10035863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044524" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113601", "target": "reaction_10044533" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10091056" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10060041" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10034238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10067254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10067247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10076375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10061043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10060963" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113519", "target": "reaction_10061122" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044148", "target": "reaction_10044480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044148", "target": "reaction_10044151" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044148", "target": "reaction_10064482" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044148", "target": "reaction_10064503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW30", "target": "species_10044148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW30", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW30", "target": "species_10044192" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072981", "target": "M0QW30" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072981", "target": "A0A3Q1MU89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCJ2", "target": "species_10044148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCJ2", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCJ2", "target": "species_10044192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCJ2", "target": "species_10044244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073532", "target": "A0A3Q1MCJ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU89", "target": "species_10044148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU89", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU89", "target": "species_10044192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCD3", "target": "species_10044148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCD3", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCD3", "target": "species_10044192" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036364", "target": "F1MCD3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071909", "target": "species_5602281" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071909", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071909", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2142713", "target": "reaction_10071909" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035953", "target": "reaction_10071909" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066325", "target": "species_10035953" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044151", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044151", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044151", "target": "species_2161636" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_266056", "target": "reaction_10044151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2161636", "target": "reaction_10064482" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073037", "target": "species_10073035" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073037" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10035507" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10057188" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10057692" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10050623" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10075063" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073156" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073021" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10064919" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10074879" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073184" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073001" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073133" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073108" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10073119" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10040303" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10040326" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10035536" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10084311" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10084131" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035491", "target": "reaction_10066082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073033", "target": "reaction_10073037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10057702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4S9", "target": "species_10036508" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019297", "target": "F1N4S9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019297", "target": "species_10036506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10057702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN51", "target": "species_10036508" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013942", "target": "F1MN51" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013942", "target": "species_10040763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10057702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP8", "target": "species_10036508" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022973", "target": "E1BFP8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022973", "target": "species_10036498" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073212" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040761" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036485" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036502" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040769" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10057704" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10057702" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040720" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036459" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040744" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073205" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10073077" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036379" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040704" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040696" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10040771" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10036399" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_190915", "target": "reaction_10040773" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190915", "target": "species_10072917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D8KXU9", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064356", "target": "D8KXU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03968", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078959", "target": "P03968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3XGD3", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029946", "target": "G3XGD3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXR4", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065993", "target": "G3MXR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHC1", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016675", "target": "E1BHC1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP37", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061318", "target": "E1BP37" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10040771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10036397" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJU2", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008940", "target": "E1BJU2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008940", "target": "species_10083928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008940", "target": "species_10083930" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008940", "target": "species_10036373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10036375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6G8", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002001", "target": "F1N6G8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10040767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHC6", "target": "species_10073205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008839", "target": "F1MHC6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073035", "target": "reaction_10073044" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073041", "target": "species_10073039" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072995", "target": "reaction_10073041" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072995", "target": "reaction_10073140" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072995", "target": "reaction_10072999" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072995", "target": "reaction_10073087" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065241", "target": "reaction_10073041" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065241", "target": "reaction_10073031" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065241", "target": "reaction_10072933" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073039", "target": "reaction_10073047" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073044", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073044", "target": "species_10039728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073047", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073047", "target": "species_10073033" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076847", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076847", "target": "species_1497857" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076847", "target": "species_76116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076847", "target": "species_5696116" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29870", "target": "reaction_10076847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29870", "target": "reaction_10043933" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29870", "target": "reaction_10058511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29870", "target": "reaction_10043948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696122", "target": "reaction_10076847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76116", "target": "reaction_10035795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76116", "target": "reaction_10049271" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76116", "target": "reaction_10051145" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076844", "target": "reaction_10076847" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069764", "target": "species_10076844" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035838", "target": "species_549167" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035838", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_75967", "target": "reaction_10035838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76103", "target": "reaction_10035838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549167", "target": "species_8866926" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549167", "target": "species_10084422" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_549167", "target": "reaction_10084480" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549167", "target": "species_10084478" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549167", "target": "species_10084692" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_549167", "target": "reaction_10083544" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10042961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10042655" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041335" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041357" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041347" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10038347" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041321" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041317" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10041319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10034231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76194", "target": "reaction_10049351" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035835", "target": "reaction_10035838" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035835", "target": "reaction_10059006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIW3", "target": "species_10035835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIW3", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIW3", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037423", "target": "F1MIW3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035795", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035795", "target": "species_76114" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76114", "target": "reaction_10058923" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76114", "target": "reaction_10051264" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035790", "target": "reaction_10035795" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030932", "target": "species_10035790" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035829", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035829", "target": "species_76103" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76108", "target": "reaction_10035829" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035826", "target": "reaction_10035829" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKP8", "target": "species_10035826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKP8", "target": "species_10069478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKP8", "target": "species_10069470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKP8", "target": "species_10059138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083005", "target": "A0A3Q1LKP8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV95", "target": "species_10035826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV95", "target": "species_10059138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067199", "target": "A0A3Q1LV95" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080887", "target": "species_76103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080887", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6800352", "target": "reaction_10080887" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10080887" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058899" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058885" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058841" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058874" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058834" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058923" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10035786" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10051264" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058993" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058998" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10059006" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10083572" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058880" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058916" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058877" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058812" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058809" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10058829" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500578", "target": "reaction_10086026" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080884", "target": "reaction_10080887" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70VZ7", "target": "species_10080884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011091", "target": "Q70VZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLQ3", "target": "species_10080884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010395", "target": "F1MLQ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYF6", "target": "species_10080884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064201", "target": "G3MYF6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090409", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090409", "target": "species_10090404" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090404", "target": "reaction_10090409" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011536", "target": "species_10090404" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090406", "target": "reaction_10090409" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061563", "target": "species_10090406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044826", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044826", "target": "species_10044819" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044815", "target": "reaction_10044826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10044815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10044819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10060581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10083449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10083423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84080", "target": "species_10083455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010159", "target": "P84080" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044823", "target": "reaction_10044826" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044823", "target": "reaction_10072401" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061619", "target": "species_10044823" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061619", "target": "E1BMC4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061619", "target": "species_10082022" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10045538", "target": "species_10045527" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10045538", "target": "species_10045525" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10045538", "target": "species_10045533" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045527", "target": "reaction_10045538" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045527", "target": "reaction_10090031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009899", "target": "species_10045527" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009899", "target": "A0A452DIB2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009899", "target": "species_10084853" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045525", "target": "reaction_10045538" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085048", "target": "species_10045525" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085048", "target": "A0A3Q1MED5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045531", "target": "reaction_10045538" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033040", "target": "species_10045531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033040", "target": "species_10045533" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033040", "target": "Q3T0Y8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045533", "target": "reaction_10085264" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045535", "target": "reaction_10045538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10045535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y8", "target": "species_10085262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MED5", "target": "species_10045535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MED5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MED5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MED5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MED5", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB2", "target": "species_10045535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB2", "target": "species_10084863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB2", "target": "species_10087813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB2", "target": "species_10090029" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034921", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034921", "target": "species_76630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111628", "target": "reaction_10034921" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034918", "target": "reaction_10034921" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034918", "target": "reaction_10034924" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034918", "target": "reaction_10034927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVC0", "target": "species_10034918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023783", "target": "F1MVC0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034924", "target": "species_111628" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034924", "target": "species_29372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111647", "target": "reaction_10034924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10034924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10033718" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10033737" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10033716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10035329" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29448", "target": "reaction_10036928" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034927", "target": "species_111647" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034927", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034927", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034927", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10034927" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10048768" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10048491" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10048478" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10066232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10058792" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111627", "target": "reaction_10058751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048761", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048761", "target": "species_83910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109277", "target": "reaction_10048761" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109277", "target": "reaction_10048754" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109277", "target": "reaction_10048747" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048761" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048754" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10041975" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044985" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10045480" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044941" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10045487" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10042657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049170" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10042648" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048567" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10067346" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049090" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049583" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044461" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10044076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10054318" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10091521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10085024" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10043978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049326" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049333" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10051276" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10086350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10085967" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049078" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049592" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049599" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049080" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10036297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10036283" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10036290" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048747" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10049083" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048601" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10048804" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10066270" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10065965" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10066021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74113", "target": "reaction_10041437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83910", "target": "reaction_10072522" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83910", "target": "reaction_10048550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83910", "target": "reaction_10053180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83910", "target": "reaction_10048491" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83910", "target": "species_426219" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83910", "target": "species_426221" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83910", "target": "species_2889081" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83910", "target": "species_2889062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83910", "target": "reaction_10066282" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048758", "target": "reaction_10048761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084837", "target": "species_10048758" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048754", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048754", "target": "species_83910" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048751", "target": "reaction_10048754" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069253", "target": "species_10048751" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065819", "target": "species_10065814" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065819", "target": "species_10065812" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065294", "target": "reaction_10065819" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065294", "target": "reaction_10065300" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004562", "target": "species_10065294" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004562", "target": "species_10065814" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004562", "target": "species_10065812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004562", "target": "P21793" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065816", "target": "reaction_10065819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU56", "target": "species_10065816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU56", "target": "species_10059671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU56", "target": "species_10059530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU56", "target": "species_10058190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU56", "target": "species_10059686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "F1MU56" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10058184" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10059733" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10059908" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10059906" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10059735" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006029", "target": "species_10059920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10065816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10059671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10059530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10058558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10058190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10059686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10059741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX6", "target": "species_10059699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "F1MTX6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059528" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059746" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059750" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059748" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10058180" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013124", "target": "species_10059915" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059674", "target": "species_10059665" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059657", "target": "reaction_10059674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEV3", "target": "species_10059657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEV3", "target": "species_10059665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEV3", "target": "species_10064421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEV3", "target": "species_10064433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEV3", "target": "species_10063809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068399", "target": "A0A3Q1MEV3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068399", "target": "species_10059655" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059671", "target": "reaction_10059674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4A6", "target": "species_10059671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4A6", "target": "species_10059530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4A6", "target": "species_10058190" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081947", "target": "A0A3Q1M4A6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081947", "target": "species_10058176" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10059671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10059801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10059728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10083102" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP1", "target": "species_10083104" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064480", "target": "G3MWP1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064480", "target": "species_10092347" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087324", "target": "species_10087319" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087324", "target": "species_10087317" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087324", "target": "species_10087315" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087324", "target": "species_10087321" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087311", "target": "reaction_10087324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018286", "target": "species_10087311" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018286", "target": "species_10087319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018286", "target": "species_10087317" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018286", "target": "species_10087315" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018286", "target": "species_10087321" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058184", "target": "reaction_10087324" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10064649", "target": "species_10064625" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064649", "target": "species_10064623" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064303", "target": "reaction_10064649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RND5", "target": "species_10064303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RND5", "target": "species_10064623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RND5", "target": "species_10062772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RND5", "target": "species_10062852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RND5", "target": "species_10064335" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039811", "target": "F6RND5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039811", "target": "species_10064625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039811", "target": "species_10062021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076984", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076984", "target": "species_5693978" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076984", "target": "species_113556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696409", "target": "reaction_10076984" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113548", "target": "reaction_10033912" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113548", "target": "reaction_10045050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113548", "target": "reaction_10039049" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076981", "target": "reaction_10076984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R9", "target": "species_10076981" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018115", "target": "E1B8R9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059533", "target": "species_10058166" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059526", "target": "reaction_10059533" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059526", "target": "reaction_10065929" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059526", "target": "reaction_10065555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLV2", "target": "species_10059526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLV2", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLV2", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLV2", "target": "species_10064957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLV2", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083510", "target": "A0A3Q1LLV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10059526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10058166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10058168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10064957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10065920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK51", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083333", "target": "A0A3Q1NK51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10059526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10058166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10058168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10064957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10065920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M970", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070553", "target": "A0A3Q1M970" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059530", "target": "reaction_10059533" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059598", "target": "species_10059595" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058699", "target": "reaction_10059598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10058699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10059595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10062749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10062335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10058697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10062205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10058703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZI7", "target": "species_10064951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063052", "target": "G3MZI7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063052", "target": "species_10062017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10058699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10059595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10062749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10062335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10058697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10062205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10058703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDT9", "target": "species_10064951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084344", "target": "A0A3Q1MDT9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084344", "target": "species_10062041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10058699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10059595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10062749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10062335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10058697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10062205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10058703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ6", "target": "species_10064951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013440", "target": "F1MJQ6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013440", "target": "species_10062045" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059528", "target": "reaction_10059598" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058561", "target": "species_10057938" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058552", "target": "reaction_10058561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10058552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10057938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10058168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10062709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10065288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10065290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10062335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10058697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10062205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10065296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10065298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10058703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02459", "target": "species_10064951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017505", "target": "P02459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017505", "target": "species_10062015" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058558", "target": "reaction_10058561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT97", "target": "species_10058558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT97", "target": "species_10058190" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "F1MT97" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10058172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10059684" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10059706" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10059899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10059704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021014", "target": "species_10059708" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10058558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10058190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0J0", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063400", "target": "G3N0J0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063400", "target": "species_10059793" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063400", "target": "species_10058188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10058558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10059910" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10059866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10059801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10059728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10066523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028731", "target": "A7YWU9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028731", "target": "species_10076243" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028731", "target": "species_10076247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028731", "target": "species_10076245" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028731", "target": "species_10058556" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059441", "target": "species_10059434" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059282", "target": "reaction_10059441" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059282", "target": "reaction_10065691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10059282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10059434" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10060183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10060185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10060189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10065689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10065296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10065298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10064955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI98", "target": "species_10064957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015668", "target": "E1BI98" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015668", "target": "species_10060111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10059282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10059434" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10060183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10060185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10060189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10065689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10065296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10065298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10064955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKG2", "target": "species_10064957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025663", "target": "F1MKG2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025663", "target": "species_10060135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10059282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10059434" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10060183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10060185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10060189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10065689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10065296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10065298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10064955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB91", "target": "species_10064957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018479", "target": "E1BB91" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018479", "target": "species_10060159" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059438", "target": "reaction_10059441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008025", "target": "species_10059438" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008025", "target": "F1MMD4" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10064705", "target": "species_10064677" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064705", "target": "species_10064703" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064651", "target": "reaction_10064705" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0N0", "target": "species_10064651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0N0", "target": "species_10064703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0N0", "target": "species_10062781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0N0", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0N0", "target": "species_10063797" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072268", "target": "A0A3Q1M0N0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072268", "target": "species_10064677" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072268", "target": "species_10062023" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058168", "target": "reaction_10058193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10058168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10059648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10058052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10062763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10064955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E303", "target": "species_10064957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018159", "target": "A7E303" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018159", "target": "species_10062019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10058168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10059648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10058052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10062763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10064955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR6", "target": "species_10064957" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083731", "target": "F1MJR6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083731", "target": "species_10062043" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058190", "target": "reaction_10058193" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059651", "target": "species_10058052" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059648", "target": "reaction_10059651" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058172", "target": "reaction_10059651" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059689", "target": "species_10058172" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059684", "target": "reaction_10059689" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059686", "target": "reaction_10059689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD4", "target": "species_10059686" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059913", "target": "species_10059908" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059913", "target": "species_10059906" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059733", "target": "reaction_10059913" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059733", "target": "reaction_10059744" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059906", "target": "reaction_10059923" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059910", "target": "reaction_10059913" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059787", "target": "species_10059750" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059787", "target": "species_10059748" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059746", "target": "reaction_10059787" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059748", "target": "reaction_10059918" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059784", "target": "reaction_10059787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10059728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10038157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10038188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10038147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ63", "target": "species_10038211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012503", "target": "Q2KJ63" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012503", "target": "species_10038133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJB8", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJB8", "target": "species_10059866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJB8", "target": "species_10066523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053990", "target": "A5PJB8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053990", "target": "A7YWU6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU6", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU6", "target": "species_10059866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWU6", "target": "species_10066523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWD8", "target": "species_10059784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWD8", "target": "species_10059866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWD8", "target": "species_10066523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076474", "target": "A0A3Q1LWD8" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059869", "target": "species_10059528" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059862", "target": "reaction_10059869" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059866", "target": "reaction_10059869" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059804", "target": "species_10058188" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059793", "target": "reaction_10059804" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059801", "target": "reaction_10059804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6H320", "target": "species_10059801" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024677", "target": "Q6H320" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059902", "target": "species_10059684" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059902", "target": "species_10059899" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059706", "target": "reaction_10059902" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059918", "target": "species_10058180" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059918", "target": "species_10059915" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059744", "target": "species_10059735" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059744", "target": "species_10058184" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059741", "target": "reaction_10059744" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25975", "target": "species_10059741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036427", "target": "P25975" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036427", "target": "A0A452DK38" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036427", "target": "species_10063945" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059731", "target": "species_10059708" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059731", "target": "species_10059706" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059704", "target": "reaction_10059731" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059728", "target": "reaction_10059731" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPI9", "target": "species_10059728" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009636", "target": "A6QPI9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAD2", "target": "species_10059728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAD2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAD2", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAD2", "target": "species_10083102" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAD2", "target": "species_10083104" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054741", "target": "E1BAD2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054741", "target": "species_10050021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8U1", "target": "species_10059728" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052512", "target": "E1B8U1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP7", "target": "species_10059728" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011737", "target": "E1BIP7" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059923", "target": "species_10059920" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059923", "target": "species_10058184" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_1604783", "target": "reaction_10059923" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:24505", "target": "species_1604783" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:24505", "target": "species_1006146" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:24505", "target": "species_10055969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_444761", "target": "species_1604783" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_444761", "target": "reaction_10049681" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_444761", "target": "species_10049679" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060003", "target": "species_10060001" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059897", "target": "reaction_10060003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N797", "target": "species_10059897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N797", "target": "species_10060001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061368", "target": "F1N797" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10068885", "target": "species_10068874" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10068885", "target": "species_10068872" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059693", "target": "reaction_10068885" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059693", "target": "reaction_10059702" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059693", "target": "reaction_10069313" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "species_10059693" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "species_10068874" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "species_10068872" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "species_10059697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "species_10059695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022744", "target": "F1MER7" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068872", "target": "reaction_10069412" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068882", "target": "reaction_10068885" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF35", "target": "species_10068882" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015593", "target": "F1MF35" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEV7", "target": "species_10068882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEV7", "target": "species_10062368" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEV7", "target": "species_10062349" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001218", "target": "E1BEV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DK38", "target": "species_10068882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DK38", "target": "species_10063969" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DK38", "target": "species_10086636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X6", "target": "species_10068882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X6", "target": "species_10062368" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007834", "target": "F1N0X6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065751", "target": "species_10065748" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063837", "target": "reaction_10065751" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063837", "target": "reaction_10065435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10063837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10065748" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10065433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10064421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10064433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTZ4", "target": "species_10063825" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020360", "target": "F1MTZ4" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058176", "target": "reaction_10065751" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087543", "target": "species_10087541" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087535", "target": "reaction_10087543" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068477", "target": "species_10087535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068477", "target": "A0A3Q1MG91" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG91", "target": "species_10087541" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059702", "target": "species_10059697" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059702", "target": "species_10059695" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059699", "target": "reaction_10059702" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061174", "target": "species_10061172" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061170", "target": "reaction_10061174" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029116", "target": "species_10061170" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029116", "target": "F1MHH9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039426", "target": "reaction_10061174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V0", "target": "species_10039765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066155", "target": "G3N0V0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0K3", "target": "species_10039765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1M0K3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1M458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1M667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1LKV0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1LLT0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "G3N188" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "G3N3Q3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1MI29" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "A0A3Q1ML26" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "G3MXG6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085031", "target": "G3N148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M458", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M667", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFI7", "target": "species_10039765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081783", "target": "A0A3Q1MFI7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKV0", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLT0", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N188", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1H5", "target": "species_10039765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064325", "target": "G3N1H5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3Q3", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI29", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML26", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXG6", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10039426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N148", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHH9", "target": "species_10061172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHH9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHH9", "target": "species_10079197" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033690", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033690", "target": "species_30471" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113552", "target": "reaction_10033690" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113552", "target": "reaction_10033757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113552", "target": "reaction_10051165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113552", "target": "reaction_10051198" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_30471", "target": "reaction_10033697" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033687", "target": "reaction_10033690" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021616", "target": "species_10033687" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_374064", "target": "reaction_10033690" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033706", "target": "species_29514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033706", "target": "species_29498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29468", "target": "reaction_10033706" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29468", "target": "reaction_10047907" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29514", "target": "reaction_10044801" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29514", "target": "reaction_10051148" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29498", "target": "reaction_10033770" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29498", "target": "reaction_10033778" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033703", "target": "reaction_10033706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ64", "target": "species_10033703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ64", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ64", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ64", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ64", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016461", "target": "Q2KJ64" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033770", "target": "species_113585" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033770", "target": "species_29968" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113567", "target": "reaction_10033770" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033767", "target": "reaction_10033770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHW4", "target": "species_10033767" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015468", "target": "Q2KHW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1S4", "target": "species_10033767" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015847", "target": "A0A3Q1N1S4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033697", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033697", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033697", "target": "species_29676" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113561", "target": "reaction_10033697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29896", "target": "reaction_10033697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29896", "target": "reaction_10058772" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113581", "target": "reaction_10033912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113581", "target": "reaction_10039049" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113581", "target": "reaction_10051075" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033694", "target": "reaction_10033697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022158", "target": "species_10033694" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084008", "target": "species_10084006" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084008", "target": "species_10083996" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083994", "target": "reaction_10084008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10083994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10084006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10086707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10077404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10056681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10056745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA10", "target": "species_10092095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055368", "target": "Q2TA10" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055368", "target": "species_10056739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10083994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10084006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10086707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10056681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10056745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N0", "target": "species_10092095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066609", "target": "A0A3Q1M5N0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083992", "target": "reaction_10084008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME38", "target": "species_10083992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME38", "target": "species_10083996" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008985", "target": "F1ME38" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084122", "target": "species_10033406" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084122", "target": "species_10033404" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084122", "target": "species_10033402" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084119", "target": "reaction_10084122" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075812", "target": "reaction_10084122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026356", "target": "species_10075812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026356", "target": "F1N3P2" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084113", "target": "species_10033394" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084113", "target": "species_10034499" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033394", "target": "reaction_10084113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084110", "target": "reaction_10084113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084110", "target": "reaction_10084117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N556", "target": "species_10084110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N556", "target": "species_10075418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N556", "target": "species_10075422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007177", "target": "F1N556" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007177", "target": "species_10066681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E630", "target": "species_10084110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050390", "target": "G5E630" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084117", "target": "species_10033398" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084117", "target": "species_10034743" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084115", "target": "reaction_10084117" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086702", "target": "species_10086700" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086688", "target": "reaction_10086702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024336", "target": "species_10086688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024336", "target": "Q3T0W3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086698", "target": "reaction_10086702" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086698", "target": "reaction_10086710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10086707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10056683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10056681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10056747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10056745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMX2", "target": "species_10092095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055723", "target": "Q1RMX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10086698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10086707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10056311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10056313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAR8", "target": "species_10056285" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084854", "target": "A0A3Q1MAR8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084854", "target": "species_10055358" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043291", "target": "reaction_10086702" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043291", "target": "reaction_10043300" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043291", "target": "reaction_10072015" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043291", "target": "reaction_10072002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018398", "target": "species_10043291" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018398", "target": "Q17QJ6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018398", "target": "species_10086705" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018398", "target": "species_10043279" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086700", "target": "reaction_10086710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10086700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10043295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10043281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10043293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10043287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10043289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10066165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10066131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10066139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10066178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10072000" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10072013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10072049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ6", "target": "species_10072051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0W3", "target": "species_10086700" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086710", "target": "species_10086707" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086710", "target": "species_10086688" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086710", "target": "species_10086705" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047210", "target": "species_10045760" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045758", "target": "reaction_10047210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK3", "target": "species_10045758" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK3", "target": "species_10045760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK3", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK3", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055896", "target": "F1MCK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI80", "target": "species_10045758" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI80", "target": "species_10045760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI80", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI80", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010601", "target": "A0A452DI80" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5C5", "target": "species_10045758" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5C5", "target": "species_10045760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5C5", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5C5", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015383", "target": "F1N5C5" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_372533", "target": "reaction_10047210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10045760" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_372533", "target": "reaction_10047214" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10046211" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10046142" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_372533", "target": "reaction_10046723" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10051518" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_372533", "target": "reaction_10051523" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_372533", "target": "species_10051495" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_372533", "target": "reaction_10051525" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047214", "target": "species_10046211" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046209", "target": "reaction_10047214" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019534", "target": "species_10046209" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019534", "target": "P41985" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41985", "target": "species_10046211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41985", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41985", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41985", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41985", "target": "species_10085114" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047224", "target": "species_10046199" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_380873", "target": "reaction_10047224" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_380873", "target": "reaction_10091556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_380873", "target": "reaction_10047222" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046197", "target": "reaction_10047224" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002768", "target": "species_10046197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002768", "target": "F1N454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N454", "target": "species_10046199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N454", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N454", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091556", "target": "species_10091554" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091552", "target": "reaction_10091556" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014422", "target": "species_10091552" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014422", "target": "F1N4I3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4I3", "target": "species_10091554" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047222", "target": "species_10047220" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047218", "target": "reaction_10047222" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062955", "target": "species_10047218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062955", "target": "Q95136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95136", "target": "species_10047220" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091929", "target": "species_10091927" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091925", "target": "reaction_10091929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054712", "target": "species_10091925" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054712", "target": "F6Q2H9" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114523", "target": "reaction_10091929" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114523", "target": "reaction_10047256" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114523", "target": "reaction_10047236" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114523", "target": "reaction_10047238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114523", "target": "reaction_10091525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q2H9", "target": "species_10091927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047256", "target": "species_10047254" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047252", "target": "reaction_10047256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLD1", "target": "species_10047252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLD1", "target": "species_10047254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067375", "target": "A0A3Q1MLD1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE22", "target": "species_10047252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE22", "target": "species_10047254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010513", "target": "E1BE22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD86", "target": "species_10047252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD86", "target": "species_10047254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD86", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD86", "target": "species_10092201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011575", "target": "E1BD86" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047236", "target": "species_10046187" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046185", "target": "reaction_10047236" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMU1", "target": "species_10046185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMU1", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMU1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMU1", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054307", "target": "F1MMU1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB93", "target": "species_10046185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB93", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB93", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB93", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037840", "target": "F1MB93" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R5F6", "target": "species_10046185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R5F6", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R5F6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R5F6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052346", "target": "F6R5F6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM3", "target": "species_10046185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM3", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM3", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061041", "target": "F1MGM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY8", "target": "species_10046185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY8", "target": "species_10046187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY8", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003759", "target": "E1BGY8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047238", "target": "species_10045784" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045782", "target": "reaction_10047238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ2", "target": "species_10045782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ2", "target": "species_10045784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ2", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017943", "target": "A0A452DIJ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QI78", "target": "species_10045782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QI78", "target": "species_10045784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QI78", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QI78", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052796", "target": "F6QI78" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047226", "target": "species_10046193" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046191", "target": "reaction_10047226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048201", "target": "species_10046191" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048201", "target": "E1BBS2" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390899", "target": "reaction_10047226" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_10046193" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390899", "target": "reaction_10091825" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_10091823" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390899", "target": "reaction_10047234" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_10047232" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_444154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_390899", "target": "species_444152" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390899", "target": "reaction_10076856" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBS2", "target": "species_10046193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBS2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBS2", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091825", "target": "species_10091823" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091821", "target": "reaction_10091825" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020802", "target": "species_10091821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020802", "target": "F1MML8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MML8", "target": "species_10091823" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047234", "target": "species_10047232" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047230", "target": "reaction_10047234" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061359", "target": "species_10047230" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061359", "target": "E1BK27" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK27", "target": "species_10047232" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090968", "target": "species_10051601" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_390627", "target": "reaction_10090968" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_390627", "target": "reaction_10047212" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_390627", "target": "reaction_10090964" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_390627", "target": "reaction_10047206" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_390627", "target": "reaction_10047765" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_390627" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051601" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10046205" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10045772" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10083948" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10084012" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10083943" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10084014" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051653" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10051660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_10085114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_444154" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_444152" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_727774" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28918", "target": "species_727737" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051599", "target": "reaction_10090968" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051599", "target": "reaction_10090960" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085511", "target": "species_10051599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085511", "target": "A0A3Q1MQZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQZ8", "target": "species_10051601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQZ8", "target": "species_10090958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQZ8", "target": "species_10090923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQZ8", "target": "species_10090921" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090958", "target": "reaction_10090968" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10090923", "target": "reaction_10090968" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10090923", "target": "reaction_10090964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10090923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10090921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10051595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10090962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10083948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10084012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10083943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10084014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28044", "target": "species_10085114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002779", "target": "Q28044" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002779", "target": "species_10051593" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090925", "target": "species_10090923" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9609307", "target": "reaction_10090925" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090921", "target": "reaction_10090925" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047212", "target": "species_10046205" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046203", "target": "reaction_10047212" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046203", "target": "reaction_10047765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065216", "target": "species_10046203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065216", "target": "A0A3Q1LQ48" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046205", "target": "reaction_10074833" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ48", "target": "species_10046205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ48", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ48", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ48", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ48", "target": "species_10051653" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090960", "target": "species_10090958" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9611836", "target": "reaction_10090960" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090964", "target": "species_10051595" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051593", "target": "reaction_10090964" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051595", "target": "reaction_10089228" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090962", "target": "reaction_10090964" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047206", "target": "species_10045772" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045770", "target": "reaction_10047206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10045770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10045772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10047204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10047202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7W0", "target": "species_10051660" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025981", "target": "E1B7W0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10045770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10045772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10047204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10047202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGA6", "target": "species_10051660" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055443", "target": "F1MGA6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047204", "target": "reaction_10047206" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10047202", "target": "reaction_10047206" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047332", "target": "species_10047330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047328", "target": "reaction_10047332" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0G5", "target": "species_10047328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0G5", "target": "species_10047330" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054907", "target": "F1N0G5" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_391200", "target": "reaction_10047332" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391200", "target": "species_10047330" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083878", "target": "species_10046124" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8851314", "target": "reaction_10083878" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8851314", "target": "species_10046124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8851314", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8851314", "target": "species_10046142" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046122", "target": "reaction_10083878" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008485", "target": "species_10046122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008485", "target": "G5E581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E581", "target": "species_10046124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E581", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E581", "target": "species_10046142" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038450", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10038450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10037022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10037037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10047947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10091247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10092055" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10047536" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30389", "target": "species_10047534" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10034157" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30389", "target": "species_10057387" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10057607" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30389", "target": "species_10044632" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30389", "target": "species_10044626" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10046623" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30389", "target": "reaction_10046630" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038447", "target": "reaction_10038450" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006874", "target": "species_10038447" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006874", "target": "species_10092052" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036570", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036570", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036567", "target": "reaction_10036570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10035503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10035505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10035525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10041848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10041865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYE0", "target": "species_10036628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028392", "target": "F1MYE0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10035503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10035505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10035525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10041848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10041865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10036628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10089837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10090415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10084389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJE0", "target": "species_10084391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015938", "target": "F1MJE0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10084303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10036552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10090842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092156" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10036540" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10077788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10036565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10065275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10092163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10036554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE24", "target": "species_10074033" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006962", "target": "A2VE24" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10084303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10036552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10090842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10090840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092156" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10077788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10036565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10065275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10092163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10036554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRU0", "target": "species_10074033" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024717", "target": "F1MRU0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024717", "target": "species_10077786" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10050571" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10084324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10036565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10065275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10066076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M864", "target": "species_10066078" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084533", "target": "A0A3Q1M864" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084533", "target": "species_10043811" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10091992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10039688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10039703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10039709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10039694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7I9", "target": "species_10084328" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025495", "target": "E1B7I9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025495", "target": "species_10072959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025495", "target": "species_10039686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10065265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10065267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10040759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10036473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10040751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPT9", "target": "species_10036485" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086336", "target": "A0A3Q1MPT9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086336", "target": "species_10040755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086336", "target": "species_10040747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10036405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10036328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY3", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011373", "target": "E1BGY3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10036405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10040742" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10040736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10036328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAV6", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086367", "target": "A0A3Q1NAV6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10036405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10040742" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10040736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10036328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL0", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086016", "target": "A0A3Q1NNL0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10040702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10036379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10040694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10036344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10040771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10036399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUE0", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083788", "target": "A0A3Q1LUE0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083788", "target": "species_10040698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083788", "target": "species_10040690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10040718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10036459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRU7", "target": "species_10073205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072473", "target": "A0A3Q1LRU7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072473", "target": "species_10040706" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072473", "target": "species_10040722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10040771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10036399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10036397" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10072950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10072954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10072952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10073324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI2", "target": "species_10072917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018586", "target": "E1BAI2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10036405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10040734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10040742" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10036432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10040736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10065255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10065257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10073131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10072974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q3", "target": "species_10073205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073054", "target": "A0A3Q1M3Q3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10036567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10056196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10047046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10073110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10065253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10057859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10084324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10046901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N339", "target": "species_10044041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002653", "target": "F1N339" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002653", "target": "species_10040231" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036607", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036607", "target": "species_10036604" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036588", "target": "reaction_10036607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NH21", "target": "species_10036588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NH21", "target": "species_10036604" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NH21", "target": "species_10036586" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076493", "target": "A0A3Q1NH21" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036596", "target": "reaction_10036607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10036596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10065097" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10091252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10091257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQJ7", "target": "species_10043289" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039221", "target": "F1MQJ7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039221", "target": "species_10036594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039221", "target": "species_10043178" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036590", "target": "species_10036580" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036590", "target": "species_10036588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036586", "target": "reaction_10036590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA10", "target": "species_10036586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA10", "target": "species_10036580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA10", "target": "species_10075628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000020594", "target": "E1BA10" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCE3", "target": "species_10036586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCE3", "target": "species_10036580" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022616", "target": "Q0VCE3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036598", "target": "species_10036596" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036594", "target": "reaction_10036598" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036594", "target": "reaction_10049279" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036594", "target": "reaction_10070657" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035507", "target": "species_10035505" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035503", "target": "reaction_10035507" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035503", "target": "reaction_10035527" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035527", "target": "species_10035525" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10035527" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10091580" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10041869" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10071508" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10043193" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035523", "target": "reaction_10066080" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055817", "target": "species_10055805" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055815", "target": "reaction_10055817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCC9", "target": "species_10064225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023702", "target": "Q3ZCC9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUW6", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080813", "target": "A0A3Q1MUW6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080813", "target": "A0A3Q1MD45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI37", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035878", "target": "E1BI37" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035878", "target": "F1MZQ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZQ5", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y5", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021451", "target": "F1N4Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW6", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080603", "target": "A0A3Q1LRW6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD45", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG36", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082227", "target": "A0A3Q1MG36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10042061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10056980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10056901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10056899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10042782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIV3", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081596", "target": "A0A3Q1MIV3" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055781" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59080", "target": "species_10055715" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10054858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236727", "target": "species_10056901" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1236727", "target": "reaction_10056903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10043580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10043657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10043642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T7", "target": "species_10064225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028280", "target": "Q3T0T7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10043655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10043657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10043653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNT8", "target": "species_10064225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043111", "target": "A6QNT8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043111", "target": "species_10043651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10043653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV07", "target": "species_10064225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004721", "target": "F1MV07" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004721", "target": "species_10043592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10055815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10055805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10043655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10043657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10055813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10043596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVW5", "target": "species_10064225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004831", "target": "F1MVW5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004831", "target": "species_10043594" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043659", "target": "species_10043657" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043655", "target": "reaction_10043659" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043655", "target": "reaction_10076775" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043580", "target": "reaction_10043659" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043580", "target": "reaction_10076775" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043657", "target": "reaction_10055819" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055819", "target": "species_10055813" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054858", "target": "reaction_10055819" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055821", "target": "species_10042061" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055781", "target": "reaction_10055821" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042061", "target": "reaction_10042129" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087807", "target": "species_10055474" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055472", "target": "reaction_10087807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL04", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL04", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL04", "target": "species_10084863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022386", "target": "Q2NL04" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022386", "target": "species_10087821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022386", "target": "species_10084861" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022386", "target": "species_10055468" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F1", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F1", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F1", "target": "species_10054864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F1", "target": "species_10054862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068015", "target": "Q5E9F1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068015", "target": "species_10044887" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068015", "target": "species_10044893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068015", "target": "species_10044891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068015", "target": "species_10044889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J6", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J6", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J6", "target": "species_10084863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020111", "target": "A5D7J6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020111", "target": "species_10087809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020111", "target": "species_10084851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020111", "target": "species_10055470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10055441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10084863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10087819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVY8", "target": "species_10084859" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011787", "target": "F1MVY8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10055472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10055474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10055441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10084863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10087819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJS0", "target": "species_10084859" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080751", "target": "E1BJS0" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_983033", "target": "reaction_10087807" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054866", "target": "species_10054862" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054866", "target": "species_10054858" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054864", "target": "reaction_10054866" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055444", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055444", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055444", "target": "species_983034" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_983032", "target": "reaction_10055444" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_983034", "target": "reaction_10055460" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10055441", "target": "reaction_10055444" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055441", "target": "reaction_10084867" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055460", "target": "species_8943716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055460", "target": "species_983033" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10055457", "target": "reaction_10055460" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078466", "target": "species_10055457" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055783", "target": "species_10055781" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055715", "target": "reaction_10055783" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039485", "target": "species_29438" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039485", "target": "species_10037043" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036954", "target": "reaction_10039485" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036954", "target": "reaction_10047979" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036954", "target": "reaction_10047823" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036954", "target": "reaction_10089203" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036954", "target": "reaction_10049039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10036954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10036952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10036956" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10047821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10089201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10083806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10037431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2V3", "target": "species_10049011" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026624", "target": "F1N2V3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10036954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10036952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10036956" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10047821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10089201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10083806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10037431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA29", "target": "species_10049011" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016160", "target": "E1BA29" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036952", "target": "reaction_10039485" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036952", "target": "reaction_10083808" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037641", "target": "species_10037611" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037609", "target": "reaction_10037641" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037609", "target": "reaction_10037618" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042737", "target": "species_10037609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042737", "target": "species_10037611" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042737", "target": "species_10037729" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042737", "target": "species_10037269" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042737", "target": "Q17QH5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037611", "target": "reaction_10038007" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10037641" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10071534" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10091773" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10068042" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10043049" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10044762" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037638", "target": "reaction_10044869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10037638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10035386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10068044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10037981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10067889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10037983" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10035390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10037987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10037989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB8", "target": "species_10044867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075852", "target": "Q2LGB8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075852", "target": "species_10035384" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037731", "target": "species_10037269" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037729", "target": "reaction_10037731" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037269", "target": "reaction_10039520" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037269", "target": "reaction_10037277" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037618", "target": "species_10037611" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037615", "target": "reaction_10037618" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037615", "target": "reaction_10092354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013262", "target": "species_10037615" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038007", "target": "species_10037729" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038004", "target": "reaction_10038007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007950", "target": "species_10038004" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007950", "target": "F1MZK0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049615", "target": "species_10046050" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046048", "target": "reaction_10049615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008619", "target": "species_10046048" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008619", "target": "B9VJV9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444210", "target": "reaction_10049615" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17120", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17120", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17120", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17120", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_444074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31011", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_444074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76179", "target": "species_429748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_444074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2022890", "target": "species_429748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_444210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_444074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30768", "target": "species_429748" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJV9", "target": "species_10046050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJV9", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJV9", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049617", "target": "species_10046044" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_400427", "target": "reaction_10049617" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_400427", "target": "reaction_10047809" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_400427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_6803778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426576", "target": "species_10047805" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50122", "target": "species_400427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50122", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50122", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50122", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_33549", "target": "species_400427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_33549", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_33549", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_33549", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_33549", "target": "reaction_10035958" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_33549", "target": "species_6803778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_400427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_6803778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_879559" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16196", "target": "species_879544" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42504", "target": "species_400427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42504", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42504", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42504", "target": "species_10046142" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046042", "target": "reaction_10049617" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046042", "target": "reaction_10047809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063172", "target": "species_10046042" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063172", "target": "G3MZT6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046044", "target": "reaction_10046723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZT6", "target": "species_10046044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZT6", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZT6", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049585", "target": "species_10046056" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046054", "target": "reaction_10049585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053502", "target": "species_10046054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053502", "target": "B9VJW0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444074", "target": "reaction_10049585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJW0", "target": "species_10046056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJW0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VJW0", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067360", "target": "species_10046491" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3296298", "target": "reaction_10067360" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3296298", "target": "species_10046491" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3296298", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3296298", "target": "species_10046513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046489", "target": "reaction_10067360" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019274", "target": "species_10046489" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019274", "target": "F1N1J4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1J4", "target": "species_10046491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1J4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1J4", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041453", "target": "species_10041451" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041447", "target": "reaction_10041453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040219", "target": "species_10041447" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040219", "target": "F1MHP5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041443", "target": "reaction_10041453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041443", "target": "reaction_10041463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHP5", "target": "species_10041451" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041463", "target": "species_10041461" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041457", "target": "reaction_10041463" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041457", "target": "reaction_10041657" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041457", "target": "reaction_10069412" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001038", "target": "species_10041457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001038", "target": "F1MWF1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10041461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10041655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10069530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10069532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10071501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10070578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWF1", "target": "species_10069410" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040328", "target": "species_10040247" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10040328" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10056201" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10073147" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10059156" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10073177" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10073129" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10073106" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10084326" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10055946" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10046903" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040231", "target": "reaction_10044043" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040245", "target": "reaction_10040328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10061477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10061466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10083475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10077599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10084842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10061456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10056771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10056779" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10057181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBE2", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013571", "target": "E1BBE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10043606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10043608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J4", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085129", "target": "A0A3Q1M7J4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10084458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10084463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10061477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10061466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10083475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10077599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10084842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10061456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10064908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10064912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10056771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10056779" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10057181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN8", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029015", "target": "E1BIN8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029015", "target": "species_10091106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029015", "target": "species_10091108" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029015", "target": "species_10040221" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10043606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10043608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV4", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024140", "target": "F1MEV4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDM2", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005295", "target": "E1BDM2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10084458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10084463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10064908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10064912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10091703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10040225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHB0", "target": "species_10044463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067365", "target": "A0A3Q1MHB0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067365", "target": "species_10040201" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040247", "target": "reaction_10040299" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040247", "target": "reaction_10040267" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040247", "target": "reaction_10040254" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040299", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040299", "target": "species_10040297" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040267", "target": "species_29372" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10040267", "target": "species_10040265" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040263", "target": "reaction_10040267" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067689", "target": "species_10040263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067689", "target": "species_10040265" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040254", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040254", "target": "species_10040251" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040277", "target": "species_10040245" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040277", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040271", "target": "reaction_10040277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043129", "target": "species_10043126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043129", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043120", "target": "reaction_10043129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10071326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10071328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10068917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10068921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEN9", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020414", "target": "E1BEN9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKL2", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKL2", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKL2", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKL2", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035270", "target": "E1BKL2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHG3", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHG3", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHG3", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHG3", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017163", "target": "F1MHG3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB15", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB15", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB15", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB15", "target": "species_10068917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB15", "target": "species_10068921" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002720", "target": "A7MB15" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W8", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W8", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W8", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W8", "target": "species_10069892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W8", "target": "species_10069894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027434", "target": "G3N2W8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMW6", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMW6", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMW6", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMW6", "target": "species_10043116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMW6", "target": "species_10068702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025757", "target": "F1MMW6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6M9", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6M9", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6M9", "target": "species_10043118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6M9", "target": "species_10043116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6M9", "target": "species_10068702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014152", "target": "F1N6M9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10043061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10068083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10068071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10068069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10068075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FK80", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087508", "target": "M5FK80" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087508", "target": "species_10041524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10043120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10043126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10043061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIC3", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056446", "target": "F1MIC3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056446", "target": "species_10041574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1K8", "target": "species_10043126" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007756", "target": "F1N1K8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071320", "target": "species_10041627" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041574", "target": "reaction_10071320" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041574", "target": "reaction_10041583" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041574", "target": "reaction_10047753" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041625", "target": "reaction_10071320" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N174", "target": "species_10041625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N174", "target": "species_10041627" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066153", "target": "G3N174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA0", "target": "species_10041625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA0", "target": "species_10041627" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010458", "target": "E1BNA0" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10041627", "target": "reaction_10041640" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10041627", "target": "reaction_10041629" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10041627", "target": "reaction_10041637" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059152", "target": "species_10043120" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043061", "target": "reaction_10059152" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043118", "target": "reaction_10059152" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083835", "target": "species_10083830" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083835", "target": "species_10083832" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083835" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10077943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10044657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10086336" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059853" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10078536" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10048995" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10054382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10054375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10086748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10086750" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10085374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10086630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10076254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10060671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10066238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10080842" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10084686" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10086248" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10088026" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059849" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10059858" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10064346" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10049241" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10049253" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10051136" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083864" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083852" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10083861" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10088982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10036207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10076856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10076863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10076884" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10041241" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10088973" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10041239" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040620" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040608" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040866" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10073378" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040868" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10040870" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10087515" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10058753" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10071754" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109276", "target": "reaction_10036209" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083828", "target": "reaction_10083835" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020127", "target": "species_10083828" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020127", "target": "species_10083830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020127", "target": "species_10083832" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083733", "target": "reaction_10083835" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083733", "target": "reaction_10083743" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083733", "target": "reaction_10083824" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070524", "target": "species_10083733" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070524", "target": "E1BGD9" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083741", "target": "species_10083733" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083741", "target": "species_10083737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083739", "target": "reaction_10083741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH0", "target": "species_10083739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025479", "target": "F1MJH0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025479", "target": "species_10083737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGD9", "target": "species_10083739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGD9", "target": "species_10083822" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083737", "target": "reaction_10083743" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10083741" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10045473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049663" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10088867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10048727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10044076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10076360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10044828" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10043986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10067388" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049869" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049635" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049358" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10049060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10048795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10048804" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10091542" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351626", "target": "reaction_10058722" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083743", "target": "species_10083739" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083824", "target": "species_10083822" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083820", "target": "reaction_10083824" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081553", "target": "species_10083820" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081553", "target": "A0A3Q1NK79" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NK79", "target": "species_10083822" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077943", "target": "species_174675" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077943", "target": "species_6789319" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171126", "target": "reaction_10077943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171126", "target": "reaction_10088982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171126", "target": "reaction_10088973" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171126", "target": "reaction_10041239" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174675", "target": "reaction_10041241" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077940", "target": "reaction_10077943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA50", "target": "species_10077940" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017778", "target": "E1BA50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MVZ9", "target": "species_10077940" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034704", "target": "G3MVZ9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084466", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084466", "target": "species_10084463" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084458", "target": "reaction_10084466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPU0", "target": "species_10084458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPU0", "target": "species_10084463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061570", "target": "E1BPU0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10084458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10084463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA8", "target": "species_10083724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061122", "target": "E1BNA8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061122", "target": "species_10083480" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061122", "target": "species_10083654" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061122", "target": "species_10083473" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061122", "target": "species_10083700" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090009", "target": "species_10090007" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090005", "target": "reaction_10090009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD15", "target": "species_10090005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD15", "target": "species_10090007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079650", "target": "A0A3Q1MD15" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089989", "target": "reaction_10090009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10089989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10090007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10091882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10091894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10089969" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10091900" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10091914" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10089965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C7", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027446", "target": "F1N7C7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091896", "target": "species_10091894" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091892", "target": "reaction_10091896" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY55", "target": "species_10091892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY55", "target": "species_10091894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023513", "target": "F1MY55" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091882", "target": "reaction_10091896" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090011", "target": "species_10089989" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089969", "target": "reaction_10090011" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089969", "target": "reaction_10091884" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089969", "target": "reaction_10091902" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089969", "target": "reaction_10089985" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089969", "target": "reaction_10091878" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091884", "target": "species_10091882" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091916", "target": "species_10091914" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091900", "target": "reaction_10091916" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091912", "target": "reaction_10091916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZP2", "target": "species_10091912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZP2", "target": "species_10091914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081390", "target": "A0A3Q1MZP2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091902", "target": "species_10091900" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089985", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089985", "target": "species_10089965" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089965", "target": "reaction_10089972" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089982", "target": "reaction_10089985" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10089982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10091876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10089949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10090336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10090079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10090195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10091918" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RWK1", "target": "species_10090243" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043933", "target": "F6RWK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10089982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10090336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10090100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10090079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10090195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10083682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B801", "target": "species_10083692" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085833", "target": "E1B801" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085833", "target": "species_10083687" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085833", "target": "species_10083680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10089982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10089949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10090336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10089146" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10090079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10090195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV5", "target": "species_10090243" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075058", "target": "A0A3Q1LWV5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089972", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089972", "target": "species_10089969" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091878", "target": "species_10091876" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091874", "target": "reaction_10091878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10091876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAJ4", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013713", "target": "E1BAJ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7A0", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7A0", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044780", "target": "A5D7A0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79132", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79132", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023751", "target": "P79132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNG7", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNG7", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075973", "target": "A0A3Q1LNG7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075973", "target": "species_10044572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075973", "target": "species_10044576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075973", "target": "species_10044574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR88", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR88", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066654", "target": "A0A3Q1LR88" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN43", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN43", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044160", "target": "A0JN43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN2", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN2", "target": "species_10091876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN2", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN2", "target": "species_10089928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061079", "target": "E1BMN2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPT9", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPT9", "target": "species_10091876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPT9", "target": "species_10081303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPT9", "target": "species_10052898" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077862", "target": "A0A3Q1LPT9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077862", "target": "species_10052892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDE1", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDE1", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086993", "target": "A0A3Q1NDE1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSB2", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSB2", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070687", "target": "A0A3Q1MSB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNB6", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNB6", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070608", "target": "A0A3Q1LNB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHQ9", "target": "species_10091874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHQ9", "target": "species_10091876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047009", "target": "E1BHQ9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057177", "target": "species_10057170" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057163", "target": "reaction_10057177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10061477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10061466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10083475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10077599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10084842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10061456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10056779" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKB4", "target": "species_10057282" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084727", "target": "A0A3Q1MKB4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084727", "target": "species_10056765" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035544", "target": "reaction_10057177" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035544", "target": "reaction_10051962" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035544", "target": "reaction_10040258" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035544", "target": "reaction_10084135" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057170", "target": "reaction_10057175" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057188", "target": "species_10057186" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057172", "target": "reaction_10057188" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057186", "target": "reaction_10057191" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057175", "target": "species_10057172" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057175", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057191", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057191", "target": "species_10039728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083712", "target": "species_429785" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083712", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_548819", "target": "reaction_10083712" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_548819", "target": "reaction_10051252" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8848483", "target": "reaction_10083712" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8848483", "target": "species_10046717" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_5684863" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_5684869" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_5686242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429785", "target": "reaction_10049189" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_10085786" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_10086062" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_10085794" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_429785", "target": "species_10085796" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083709", "target": "reaction_10083712" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087371", "target": "species_10083709" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087371", "target": "G5E5P6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083004", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083004", "target": "species_10083001" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082997", "target": "reaction_10083004" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10083001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10083375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWA3", "target": "species_10082042" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083281", "target": "A0A3Q1MWA3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10082997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10083001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10082995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10082024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMC4", "target": "species_10082042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10082997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10083001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10082034" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10082042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10072421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10072399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10072322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV05", "target": "species_10072324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074696", "target": "A0A3Q1LV05" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083006", "target": "species_10082995" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082022", "target": "reaction_10083006" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082022", "target": "reaction_10082026" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082993", "target": "reaction_10083006" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082995", "target": "reaction_10082999" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082999", "target": "species_10082997" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082034", "target": "reaction_10082999" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082034", "target": "reaction_10082038" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049867", "target": "species_29420" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049867", "target": "species_449283" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162860", "target": "reaction_10049867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162860", "target": "reaction_10049851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162860", "target": "reaction_10077823" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162860", "target": "reaction_10051587" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449293", "target": "reaction_10049867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449283", "target": "reaction_10049851" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049864", "target": "reaction_10049867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002836", "target": "species_10049864" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049851", "target": "species_449737" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049851", "target": "species_29420" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049848", "target": "reaction_10049851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003187", "target": "species_10049848" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049789", "target": "species_449311" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049789", "target": "species_449315" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449229", "target": "reaction_10049789" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449229", "target": "reaction_10049811" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449229", "target": "reaction_10049858" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449229", "target": "reaction_10049860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449229", "target": "reaction_10038464" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449298", "target": "reaction_10049789" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449315", "target": "reaction_10049858" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049782", "target": "reaction_10049789" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032212", "target": "species_10049782" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049787", "target": "reaction_10049789" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049787", "target": "reaction_10049811" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049787", "target": "reaction_10049858" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049787", "target": "reaction_10049860" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000147", "target": "species_10049787" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049811", "target": "species_449311" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049811", "target": "species_449365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449312", "target": "reaction_10049811" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449365", "target": "reaction_10049860" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049808", "target": "reaction_10049811" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064352", "target": "species_10049808" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049858", "target": "species_449311" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049858", "target": "species_449312" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049855", "target": "reaction_10049858" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049855", "target": "reaction_10049860" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052671", "target": "species_10049855" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082941", "target": "species_29548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082941", "target": "species_109402" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10082941" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29410", "target": "species_744229" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29410", "target": "species_744234" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29410", "target": "species_10046229" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29410", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29410", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10067610" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10067644" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10068755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10067639" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10067622" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29410", "target": "reaction_10039749" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29548", "target": "reaction_10033594" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_8851227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_8851461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500761" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500420" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500316" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109402", "target": "species_500347" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10082938", "target": "reaction_10082941" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063951", "target": "species_10082938" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077816", "target": "species_6787646" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787618", "target": "reaction_10077816" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787646", "target": "reaction_10077826" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077813", "target": "reaction_10077816" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077813", "target": "reaction_10077826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2A1", "target": "species_10077813" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082106", "target": "A0A3Q1M2A1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077800", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077800", "target": "species_742368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787542", "target": "reaction_10077800" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077797", "target": "reaction_10077800" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055149", "target": "species_10077797" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077823", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077823", "target": "species_6787618" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077820", "target": "reaction_10077823" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015992", "target": "species_10077820" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077807", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077807", "target": "species_6787542" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787678", "target": "reaction_10077807" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077804", "target": "reaction_10077807" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085459", "target": "species_10077804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077826", "target": "species_742368" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077826", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049831", "target": "species_532531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_532562", "target": "reaction_10049831" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049828", "target": "reaction_10049831" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC17", "target": "species_10049828" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076692", "target": "Q0VC17" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZJ9", "target": "species_10049828" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001888", "target": "Q3SZJ9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069368", "target": "species_110096" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069368", "target": "species_4085214" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10069368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10049797" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10049844" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10091793" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10051577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162756", "target": "reaction_10039874" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4085214", "target": "reaction_10069371" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069365", "target": "reaction_10069368" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069365", "target": "reaction_10069371" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIL9", "target": "species_10069365" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001520", "target": "F1MIL9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069320", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069320", "target": "species_4085390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4085225", "target": "reaction_10069320" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29492", "target": "reaction_10069320" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29492", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4085390", "target": "reaction_10069357" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069317", "target": "reaction_10069320" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025318", "target": "species_10069317" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069371", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069371", "target": "species_4085225" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069357", "target": "species_428633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069357", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069354", "target": "reaction_10069357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM8", "target": "species_10069354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000918", "target": "A7YWM8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069373", "target": "species_428633" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069373", "target": "species_4088123" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_4088202", "target": "reaction_10069373" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086294", "target": "species_4088202" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086341", "target": "species_4088202" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4087982", "target": "species_4088202" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4087982", "target": "species_4088088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086277", "target": "species_4088202" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086277", "target": "species_4088088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4088006", "target": "species_4088123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4088006", "target": "species_4088103" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4088006", "target": "reaction_10069329" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086285", "target": "species_4088123" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086285", "target": "species_4088103" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4086285", "target": "reaction_10069348" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4086285", "target": "reaction_10069382" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_4086301", "target": "species_4088123" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4086301", "target": "reaction_10069346" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059958", "target": "reaction_10069373" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059958", "target": "reaction_10059961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027552", "target": "species_10059958" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069359", "target": "species_428633" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069359", "target": "species_4088103" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_4088088", "target": "reaction_10069359" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059981", "target": "reaction_10069359" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059981", "target": "reaction_10059984" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036738", "target": "species_10059981" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048958", "target": "species_428633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048958", "target": "species_70106" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428040", "target": "reaction_10048958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428040", "target": "reaction_10048802" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428639", "target": "reaction_10048958" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048955", "target": "reaction_10048958" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061225", "target": "species_10048955" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069329", "target": "species_727810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069329", "target": "species_4087982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10069329" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10069346" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10069348" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10069382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10054575" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10054766" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10054722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10054773" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10054550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10063530" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10090851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10090802" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727815", "target": "reaction_10090822" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_727810", "target": "reaction_10051554" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_8851227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_8851461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_500761" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_500828" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_500009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_6788778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_6788802" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_500316" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_727810", "target": "species_500347" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069326", "target": "reaction_10069329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8K2", "target": "species_10069326" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074715", "target": "A0A3Q1N8K2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM08", "target": "species_10069326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM08", "target": "species_10056071" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077891", "target": "A0A3Q1LM08" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZS9", "target": "species_10069326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZS9", "target": "species_10056071" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068182", "target": "A0A3Q1LZS9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051554", "target": "species_727815" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051554", "target": "species_109395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4085435", "target": "reaction_10051554" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051551", "target": "reaction_10051554" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018680", "target": "species_10051551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069346", "target": "species_4086341" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069346", "target": "species_727810" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069343", "target": "reaction_10069346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXN8", "target": "species_10069343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009616", "target": "F1MXN8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3B2", "target": "species_10069343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063122", "target": "G3N3B2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063122", "target": "species_10054763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJH9", "target": "species_10069343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061027", "target": "A0A452DJH9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061027", "target": "species_10069341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX1", "target": "species_10069343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078008", "target": "A0A3Q1LRX1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078008", "target": "species_10054770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6V7", "target": "species_10069343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034693", "target": "F1N6V7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069348", "target": "species_4086277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069348", "target": "species_727810" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054719", "target": "reaction_10069348" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054719", "target": "reaction_10054722" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054719", "target": "reaction_10063530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUC6", "target": "species_10054719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUC6", "target": "species_10090848" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078218", "target": "A0A3Q1LUC6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078218", "target": "species_10054713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH3", "target": "species_10054719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH3", "target": "species_10090848" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075324", "target": "A0A3Q1MGH3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075324", "target": "species_10054717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D960", "target": "species_10054719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001538", "target": "A5D960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6H8M9", "target": "species_10054719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086395", "target": "Q6H8M9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069382", "target": "species_727810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069382", "target": "species_4086294" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069379", "target": "reaction_10069382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M347", "target": "species_10069379" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083430", "target": "A0A3Q1M347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083430", "target": "species_10054415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7T4", "target": "species_10069379" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070130", "target": "A5D7T4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069498", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069498", "target": "species_449221" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4419981", "target": "reaction_10069498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449221", "target": "reaction_10049804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049818", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049818", "target": "species_449299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449744", "target": "reaction_10049818" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449299", "target": "reaction_10049797" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049815", "target": "reaction_10049818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023834", "target": "species_10049815" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049804", "target": "species_110094" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049804", "target": "species_449299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_110614", "target": "reaction_10049804" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110614", "target": "species_30595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_110614", "target": "reaction_10059130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_110614", "target": "reaction_10059091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110614", "target": "species_8936166" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110614", "target": "species_8851233" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110614", "target": "species_8851509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110614", "target": "species_482807" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_8851092" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_8851224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_8851462" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_8851518" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_500006" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_6788782" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_482803" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_110094", "target": "species_6788801" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049801", "target": "reaction_10049804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014016", "target": "species_10049801" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040933", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040933", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040933", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040933", "target": "species_191362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191403", "target": "reaction_10040933" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113528", "target": "reaction_10058790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113528", "target": "reaction_10057062" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113528", "target": "reaction_10044851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113528", "target": "reaction_10058755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113528", "target": "reaction_10035332" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191362", "target": "reaction_10040892" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191362", "target": "reaction_10040895" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191362", "target": "reaction_10040913" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040930", "target": "reaction_10040933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P570", "target": "species_10040930" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015994", "target": "Q0P570" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049797", "target": "species_109402" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049797", "target": "species_449222" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_449222", "target": "reaction_10049844" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049794", "target": "reaction_10049797" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070574", "target": "species_10049794" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049844", "target": "species_449293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049844", "target": "species_110096" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049841", "target": "reaction_10049844" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU60", "target": "species_10049841" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006020", "target": "F1MU60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MW72", "target": "species_10049841" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076761", "target": "A0A3Q1MW72" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049860", "target": "species_449371" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049860", "target": "species_449311" }, { "type": "product", "sub_type": "", "source": "reaction_10056074", "target": "species_981615" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975925", "target": "reaction_10056074" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975925", "target": "reaction_10056061" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975925", "target": "reaction_10054418" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10056074" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10056061" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10054431" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10054467" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10054418" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10054438" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975910", "target": "reaction_10054474" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056071", "target": "reaction_10056074" }, { "type": "product", "sub_type": "", "source": "reaction_10056061", "target": "species_981615" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054717", "target": "reaction_10056061" }, { "type": "product", "sub_type": "", "source": "reaction_10054431", "target": "species_981616" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10054431" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10054438" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10054474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10054411" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10053331" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_914003", "target": "species_744229" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_914003", "target": "species_744234" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10052665" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10052716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10052606" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10052496" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10052546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10076773" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_914003", "target": "reaction_10063249" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054428", "target": "reaction_10054431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNB2", "target": "species_10054428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014809", "target": "E1BNB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ63", "target": "species_10054428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049734", "target": "A6QQ63" }, { "type": "product", "sub_type": "", "source": "reaction_10054467", "target": "species_981618" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10054467" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10052521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10061538" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10072894" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10072898" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10063532" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10063232" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10063520" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10061402" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10061395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10090631" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735682", "target": "reaction_10090819" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054464", "target": "reaction_10054467" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054464", "target": "reaction_10063532" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054464", "target": "reaction_10063232" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054464", "target": "reaction_10063520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RH18", "target": "species_10054464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047259", "target": "F6RH18" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10054464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10072891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08037", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020286", "target": "P08037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020286", "target": "species_10054442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCQ2", "target": "species_10054464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061252", "target": "E1BCQ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RJ53", "target": "species_10054464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015761", "target": "F6RJ53" }, { "type": "product", "sub_type": "", "source": "reaction_10054418", "target": "species_981615" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054415", "target": "reaction_10054418" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054415", "target": "reaction_10054575" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054415", "target": "reaction_10054550" }, { "type": "product", "sub_type": "", "source": "reaction_10054438", "target": "species_981617" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054435", "target": "reaction_10054438" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084669", "target": "species_10054435" }, { "type": "product", "sub_type": "", "source": "reaction_10054474", "target": "species_981613" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054471", "target": "reaction_10054474" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016591", "target": "species_10054471" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054411", "target": "species_205687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054411", "target": "species_975822" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975819", "target": "reaction_10054411" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_10045834" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_10045894" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_8851092" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_8851224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_8851462" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_8851518" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_500006" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_205687", "target": "species_482803" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054408", "target": "reaction_10054411" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048092", "target": "species_10054408" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076415", "target": "species_6784248" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076415", "target": "species_6784249" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10076415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10091293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060295" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10059991" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10059977" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10059944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10059951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10059968" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10063801" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10063803" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060685" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060625" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060741" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060678" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060825" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10091289" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060827" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060842" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060829" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10060031" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10063807" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10091291" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10064593" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10064355" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10064595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10064597" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10084129" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10080756" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10090696" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605715", "target": "reaction_10081481" }, { "type": "reactant", "sub_type": "", "source": "species_6784247", "target": "reaction_10076415" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076412", "target": "reaction_10076415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIM0", "target": "species_10076412" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIM0", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIM0", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042970", "target": "Q2KIM0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077710", "target": "species_10077703" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077710", "target": "species_742343" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10077710" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10077717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10062984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063610" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063633" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063603" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063586" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10077688" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10091630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10063508" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10061612" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10062463" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10062697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10062674" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_741440", "target": "reaction_10088617" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077694", "target": "reaction_10077710" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_742343", "target": "reaction_10088580" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077707", "target": "reaction_10077710" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064164", "target": "species_10077707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077717", "target": "species_742343" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077717", "target": "species_6786380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6786371", "target": "reaction_10077717" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077714", "target": "reaction_10077717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082120", "target": "species_10077714" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076422", "target": "species_5693933" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076422", "target": "species_205689" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693930", "target": "reaction_10076422" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10076422" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090703" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090797" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090774" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_205683", "target": "reaction_10090854" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076419", "target": "reaction_10076422" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076419", "target": "reaction_10090856" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076419", "target": "reaction_10090799" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076419", "target": "reaction_10090854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000529", "target": "species_10076419" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000529", "target": "F1MBS8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076696", "target": "species_10076694" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076692", "target": "reaction_10076696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078548", "target": "species_10076692" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078548", "target": "A0A3Q1LM15" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043646", "target": "reaction_10076696" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043646", "target": "reaction_10043649" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009307", "target": "species_10043646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009307", "target": "E1BL12" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL12", "target": "species_10076694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM15", "target": "species_10076694" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076586", "target": "species_10043596" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043590", "target": "reaction_10076586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10043590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10043596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDZ1", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083081", "target": "A0A3Q1NDZ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10043590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10043596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB5", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046561", "target": "Q08DB5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043594", "target": "reaction_10076586" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043594", "target": "reaction_10076590" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043592", "target": "reaction_10076586" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076590", "target": "species_10076588" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043539", "target": "reaction_10076590" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043539", "target": "reaction_10084867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066705", "target": "species_10043539" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066705", "target": "A0A3Q1MMA1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066705", "target": "species_10076669" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043651", "target": "reaction_10076590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10084863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMA1", "target": "species_10087813" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076706", "target": "species_10043624" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043622", "target": "reaction_10076706" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082647", "target": "species_10043622" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082647", "target": "G0T3G6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043618", "target": "reaction_10076706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10043618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10043624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUP7", "target": "species_10076608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076684", "target": "A0A3Q1LUP7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10043618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10043624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N355", "target": "species_10076608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081836", "target": "A0A3Q1N355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10043624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G0T3G6", "target": "species_10076608" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076708", "target": "species_10043608" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043606", "target": "reaction_10076708" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043600", "target": "reaction_10076708" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025975", "target": "species_10043600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025975", "target": "Q5BIN6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10043608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10043626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10043628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN6", "target": "species_10076608" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076775", "target": "species_10043628" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043626", "target": "reaction_10076775" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043628", "target": "reaction_10076778" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076584", "target": "species_10076581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076584", "target": "species_29420" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076577", "target": "reaction_10076584" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKW5", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKW5", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKW5", "target": "species_10076537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKW5", "target": "species_10076608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009785", "target": "E1BKW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10076493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10086115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10065087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N147", "target": "species_10065092" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070415", "target": "A0A3Q1N147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T086", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T086", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T086", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T086", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T086", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009288", "target": "Q3T086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRB3", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRB3", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRB3", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRB3", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRB3", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079685", "target": "A0A3Q1MRB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10086133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QI1", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065281", "target": "Q17QI1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L78", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L78", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L78", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L78", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L78", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019999", "target": "Q32L78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBL9", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBL9", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBL9", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBL9", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBL9", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010619", "target": "Q2TBL9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4U3", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4U3", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4U3", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4U3", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4U3", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087207", "target": "A0A3Q1M4U3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSD6", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSD6", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSD6", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSD6", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSD6", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005590", "target": "F1MSD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F2", "target": "species_10076577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F2", "target": "species_10076581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F2", "target": "species_10076575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F2", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F2", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014509", "target": "Q3T0F2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076581", "target": "reaction_10076610" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076635", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076635", "target": "species_10043653" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076618", "target": "reaction_10076635" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076632", "target": "reaction_10076635" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN43", "target": "species_10076632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034553", "target": "E1BN43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIC7", "target": "species_10076632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010568", "target": "Q2KIC7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N214", "target": "species_10076632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066016", "target": "G3N214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076778", "target": "species_10043655" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076778", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076778", "target": "species_10043626" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076778", "target": "species_10043642" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043642", "target": "reaction_10043649" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076698", "target": "species_10076577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076575", "target": "reaction_10076698" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076493", "target": "reaction_10076698" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076537", "target": "reaction_10076698" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043649", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043649", "target": "species_10043580" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083377", "target": "species_10083375" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082020", "target": "reaction_10083377" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082020", "target": "reaction_10082026" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083373", "target": "reaction_10083377" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017725", "target": "species_10083373" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017725", "target": "Q2T9Q1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083375", "target": "reaction_10083380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9Q1", "target": "species_10083375" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076736", "target": "species_10076596" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076736", "target": "species_10076677" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076736", "target": "species_10076734" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076736", "target": "species_10076602" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076704", "target": "reaction_10076736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10076602" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10082024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10082036" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P41541", "target": "species_10082042" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022642", "target": "P41541" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTM9", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTM9", "target": "species_10076596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTM9", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTM9", "target": "species_10065087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTM9", "target": "species_10065092" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084718", "target": "A0A3Q1LTM9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M072", "target": "species_10076704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M072", "target": "species_10076596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M072", "target": "species_10076608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M072", "target": "species_10065087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M072", "target": "species_10065092" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084758", "target": "A0A3Q1M072" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076667", "target": "reaction_10076736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE3", "target": "species_10076667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE3", "target": "species_10076677" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082298", "target": "A0A3Q1MJE3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG76", "target": "species_10076667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG76", "target": "species_10076677" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046085", "target": "E1BG76" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076596", "target": "reaction_10076610" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076602", "target": "reaction_10076610" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076602", "target": "reaction_10082026" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076610", "target": "species_10076608" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083380", "target": "species_10083373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083380", "target": "species_10076493" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082026", "target": "species_10082024" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082024", "target": "reaction_10082038" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082045", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082045", "target": "species_10082042" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082036", "target": "reaction_10082045" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082038", "target": "species_10082036" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053337", "target": "species_964752" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053337", "target": "species_964740" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_964831", "target": "reaction_10053337" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60629", "target": "species_964831" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60629", "target": "species_10056056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60628", "target": "species_964831" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60628", "target": "species_10056056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60627", "target": "species_964831" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:60627", "target": "species_10056056" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964740", "target": "reaction_10053331" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_964740", "target": "species_10056056" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053314", "target": "reaction_10053337" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053314", "target": "reaction_10053339" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053314", "target": "reaction_10053317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNG2", "target": "species_10053314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061143", "target": "E1BNG2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKX0", "target": "species_10053314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072527", "target": "A0A3Q1MKX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7B0", "target": "species_10053314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061594", "target": "E1B7B0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053339", "target": "species_964752" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053339", "target": "species_964740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964828", "target": "reaction_10053339" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053317", "target": "species_964752" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053317", "target": "species_964740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_915149", "target": "reaction_10053317" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_915149", "target": "species_10056056" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053324", "target": "species_964744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053324", "target": "species_964746" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964754", "target": "reaction_10053324" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964746", "target": "reaction_10072894" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10053321", "target": "reaction_10053324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006614", "target": "species_10053321" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053331", "target": "species_964837" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053331", "target": "species_205687" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10053328", "target": "reaction_10053331" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066191", "target": "species_10053328" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084373", "target": "species_10084371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8855720", "target": "reaction_10084373" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8855720", "target": "species_10084371" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084369", "target": "reaction_10084373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KM0", "target": "species_10084369" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KM0", "target": "species_10084371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016010", "target": "Q32KM0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME82", "target": "species_10084369" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME82", "target": "species_10084371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035098", "target": "F1ME82" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056058", "target": "species_10056056" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056054", "target": "reaction_10056058" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089384", "target": "reaction_10089391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10089384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02372", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000100", "target": "Q02372" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089388", "target": "reaction_10089391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046212", "target": "species_10089388" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056912", "target": "species_10056803" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056833", "target": "reaction_10056912" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236715", "target": "species_10056833" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236715", "target": "species_10056803" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236715", "target": "species_10056819" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1236715", "target": "species_6788991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB51", "target": "species_10056833" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB51", "target": "species_10056803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB51", "target": "species_10056819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB51", "target": "species_10056801" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005993", "target": "E1BB51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP99", "target": "species_10056833" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP99", "target": "species_10056803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP99", "target": "species_10056819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP99", "target": "species_10056801" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011333", "target": "A0A3S5ZP99" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056803", "target": "reaction_10056805" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056835", "target": "species_10056833" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056819", "target": "reaction_10056835" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056805", "target": "species_1236715" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056805", "target": "species_10056801" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087823", "target": "species_10087813" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087823", "target": "species_10087809" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087823", "target": "species_10087821" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087823", "target": "species_10087819" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084863", "target": "reaction_10087823" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084865", "target": "species_10084863" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084853", "target": "reaction_10084865" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084851", "target": "reaction_10084865" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084861", "target": "reaction_10084865" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076669", "target": "reaction_10084865" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084859", "target": "reaction_10084865" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084867", "target": "species_10084851" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084867", "target": "species_10084861" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084867", "target": "species_10076669" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084867", "target": "species_10084859" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055470", "target": "reaction_10084867" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055468", "target": "reaction_10084867" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056982", "target": "species_10042061" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056980", "target": "reaction_10056982" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056910", "target": "species_8943711" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056910", "target": "species_1236727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1236722", "target": "reaction_10056910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056907", "target": "reaction_10056910" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAQ4", "target": "species_10056907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAQ4", "target": "species_10055488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080071", "target": "A0A3Q1MAQ4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056914", "target": "species_10042061" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056901", "target": "reaction_10056914" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056903", "target": "species_10056901" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056899", "target": "reaction_10056903" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057004", "target": "species_2000345" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057004", "target": "species_2000349" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057004", "target": "species_2000348" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1236709", "target": "reaction_10057004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1236709", "target": "reaction_10073731" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2000347", "target": "reaction_10057004" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057001", "target": "reaction_10057004" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057001", "target": "reaction_10090091" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057001", "target": "reaction_10073716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10057001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10073752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46521", "target": "species_10056405" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067849", "target": "O46521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10057001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10073752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10091177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10091162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10091166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10091173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY1", "target": "species_10056405" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004279", "target": "A0A452DHY1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10057001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10091177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10091162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10091166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10091173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKI4", "target": "species_10056405" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084691", "target": "A0A3Q1MKI4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10057001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10073752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10091177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10091162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10091166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10091173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW8", "target": "species_10056405" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076657", "target": "A0A3Q1MTW8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041962", "target": "species_198827" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_198852", "target": "reaction_10041962" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_198827", "target": "reaction_10041955" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041959", "target": "reaction_10041962" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042889", "target": "species_10041959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042889", "target": "A2VDL2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041955", "target": "species_198816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041955", "target": "species_111745" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111745", "target": "reaction_10034166" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041952", "target": "reaction_10041955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BED9", "target": "species_10041952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BED9", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005211", "target": "E1BED9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041975", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041975", "target": "species_198816" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_198836", "target": "reaction_10041975" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_198836", "target": "species_10056699" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_198836", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_198836", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_198836", "target": "species_10056716" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_198836", "target": "species_10056661" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041972", "target": "reaction_10041975" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI45", "target": "species_10041972" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010823", "target": "E1BI45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP61", "target": "species_10041972" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083275", "target": "E1BP61" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083656", "target": "species_10083654" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083656" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083487" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083558" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083632" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083581" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083684" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083622" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083707" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083480", "target": "reaction_10083726" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083654", "target": "reaction_10083664" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083672", "target": "species_10083654" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083672", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083672", "target": "species_10083669" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083662", "target": "reaction_10083672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RQ2", "target": "species_10083662" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016581", "target": "Q29RQ2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016581", "target": "species_10083669" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016581", "target": "species_10083674" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016581", "target": "species_10083660" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083669", "target": "reaction_10083676" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083676", "target": "species_10083674" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083664", "target": "species_10083662" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083660", "target": "reaction_10083664" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037748", "target": "species_140357" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10037748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10065216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10064511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10064531" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10064516" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_140356", "target": "species_10073729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10044216" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10044195" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10044260" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_140356", "target": "species_6803778" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140356", "target": "reaction_10044242" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_140356", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_140356", "target": "species_10047805" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140357", "target": "reaction_10037751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140357", "target": "reaction_10065210" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037745", "target": "reaction_10037748" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037745", "target": "reaction_10037751" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037745", "target": "reaction_10065223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI94", "target": "species_10037745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI94", "target": "species_10065221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008833", "target": "A0A452DI94" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26355", "target": "species_10037745" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26355", "target": "species_10064543" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26355", "target": "species_10065205" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26355", "target": "species_10065208" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26355", "target": "species_10065221" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037751", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037751", "target": "species_30138" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76342", "target": "reaction_10037751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76342", "target": "reaction_10065210" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30138", "target": "reaction_10064452" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063448", "target": "species_2046048" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063448", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063448", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063448", "target": "species_159751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063413" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063456" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063440" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046066", "target": "reaction_10063430" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046060", "target": "reaction_10063448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046048", "target": "reaction_10063452" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162743", "target": "reaction_10063454" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_162743", "target": "reaction_10063425" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051239", "target": "reaction_10063448" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051239", "target": "reaction_10063440" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074314", "target": "species_10051239" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074314", "target": "A4FUF2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063450", "target": "species_194653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063450", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063450", "target": "species_2046042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194697", "target": "reaction_10063450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194697", "target": "reaction_10063452" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194697", "target": "reaction_10063442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194697", "target": "reaction_10063437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194697", "target": "reaction_10063420" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046063", "target": "reaction_10063450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194653", "target": "reaction_10060109" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046042", "target": "reaction_10063446" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063417", "target": "reaction_10063450" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063417", "target": "reaction_10063452" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063417", "target": "reaction_10063420" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020610", "target": "species_10063417" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063452", "target": "species_194653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063452", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063452", "target": "species_2046050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046050", "target": "reaction_10063444" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063454", "target": "species_2046064" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063454", "target": "species_2046049" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063454", "target": "species_2046063" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211579", "target": "reaction_10063454" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211579", "target": "reaction_10063444" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211579", "target": "reaction_10063425" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211579", "target": "reaction_10063428" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211579", "target": "reaction_10060773" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046044", "target": "reaction_10063454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046044", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046044", "target": "species_10047805" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063422", "target": "reaction_10063454" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063422", "target": "reaction_10063425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWT4", "target": "species_10063422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWT4", "target": "species_10042958" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078831", "target": "A0A3Q1LWT4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063442", "target": "species_194653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063442", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063442", "target": "species_2046053" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046045", "target": "reaction_10063442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046053", "target": "reaction_10063413" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063434", "target": "reaction_10063442" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063434", "target": "reaction_10063437" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082100", "target": "species_10063434" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063413", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063413", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063413", "target": "species_159751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063413", "target": "species_2046060" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063410", "target": "reaction_10063413" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063410", "target": "reaction_10063456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJD9", "target": "species_10063410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJD9", "target": "species_10051249" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004358", "target": "Q2KJD9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUF2", "target": "species_10063410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUF2", "target": "species_10051249" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063444", "target": "species_5228339" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063444", "target": "species_2046055" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063444", "target": "species_211606" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046702", "target": "reaction_10063444" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046702", "target": "reaction_10063428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027382", "target": "species_10046702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027382", "target": "Q2KJ57" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063446", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063446", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063446", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063446", "target": "species_159751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063446", "target": "species_2046045" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051249", "target": "reaction_10063446" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051249", "target": "reaction_10063430" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051249", "target": "reaction_10051252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBR7", "target": "species_10051249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBR7", "target": "species_10051258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020842", "target": "E1BBR7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063437", "target": "species_194653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063437", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063437", "target": "species_2046059" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046051", "target": "reaction_10063437" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046059", "target": "reaction_10063456" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063420", "target": "species_194653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063420", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063420", "target": "species_2046052" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046062", "target": "reaction_10063420" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046052", "target": "reaction_10063430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063425", "target": "species_2046064" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063425", "target": "species_2046049" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063425", "target": "species_2046062" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046056", "target": "reaction_10063425" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046056", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046056", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046056", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046056", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2046056", "target": "species_10047805" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063456", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063456", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063456", "target": "species_2046057" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063456", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063456", "target": "species_159751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046057", "target": "reaction_10063440" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063440", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063440", "target": "species_2046065" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063440", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063440", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063440", "target": "species_159751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063570", "target": "species_193514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063570", "target": "species_2066763" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10063570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10047056" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10075576" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10047022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10082143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10090604" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_141343", "target": "reaction_10041308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2066765", "target": "reaction_10063570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193514", "target": "reaction_10063573" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193514", "target": "reaction_10047053" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193514", "target": "reaction_10046989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193514", "target": "reaction_10046992" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041305", "target": "reaction_10063570" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041305", "target": "reaction_10047056" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041305", "target": "reaction_10041308" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074004", "target": "species_10041305" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074004", "target": "A0A3Q1N6L4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063573", "target": "species_353123" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063573", "target": "species_2066765" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2066762", "target": "reaction_10063573" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_353123", "target": "reaction_10047056" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047050", "target": "reaction_10063573" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047050", "target": "reaction_10047053" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024335", "target": "species_10047050" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024335", "target": "Q3ZC41" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063428", "target": "species_426639" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063428", "target": "species_211606" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063428", "target": "species_2046047" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2046054", "target": "reaction_10063428" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063430", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063430", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063430", "target": "species_2046051" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063430", "target": "species_162743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063430", "target": "species_159751" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_70843" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_113593" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_29376" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033912", "target": "species_71019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70843", "target": "reaction_10033912" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_71019", "target": "reaction_10033912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71019", "target": "reaction_10033896" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033909", "target": "reaction_10033912" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N969", "target": "species_10033909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N969", "target": "species_10066388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N969", "target": "species_10066394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086761", "target": "A0A3Q1N969" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR0", "target": "species_10033909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR0", "target": "species_10066388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR0", "target": "species_10066394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020252", "target": "A0A452DIR0" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033896", "target": "species_71019" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033896", "target": "species_71009" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_71009", "target": "reaction_10033896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71009", "target": "reaction_10033889" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033893", "target": "reaction_10033896" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049741", "target": "species_10033893" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033889", "target": "species_70958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70958", "target": "reaction_10035415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70958", "target": "reaction_10040682" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033884", "target": "reaction_10033889" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3159297", "target": "species_10033884" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3159297", "target": "reaction_10066587" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0III1", "target": "species_10033884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0III1", "target": "species_10033882" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076678", "target": "Q0III1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQI8", "target": "species_10033884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQI8", "target": "species_10033882" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029806", "target": "A6QQI8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075631", "target": "species_29374" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075631", "target": "species_5690519" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5690540", "target": "reaction_10075631" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33184", "target": "species_5690540" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33184", "target": "species_5690044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33184", "target": "species_5690520" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:61907", "target": "species_5690540" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:61907", "target": "species_5690044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:61907", "target": "species_5690520" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30495", "target": "species_5690519" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30495", "target": "species_5690064" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30495", "target": "species_5690539" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_30495", "target": "reaction_10039604" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59554", "target": "species_5690519" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59554", "target": "species_5690064" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59554", "target": "species_5690539" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075628", "target": "reaction_10075631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQA9", "target": "species_10075628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQA9", "target": "species_10075600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074250", "target": "A6QQA9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074250", "target": "F1N234" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N234", "target": "species_10075628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAC0", "target": "species_10075628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000922", "target": "E1BAC0" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036029", "target": "species_113526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036029", "target": "species_77330" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036029", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036029", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036029", "target": "species_77328" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77330", "target": "reaction_10036029" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77328", "target": "reaction_10036029" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036009", "target": "reaction_10036029" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036009", "target": "reaction_10036027" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036009", "target": "reaction_10036040" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036009", "target": "reaction_10036012" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036009", "target": "reaction_10036025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS03", "target": "species_10036009" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054475", "target": "A0A3Q1LS03" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036038", "target": "species_113596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036038", "target": "species_77337" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036038", "target": "species_77332" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036038", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77337", "target": "reaction_10036038" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77332", "target": "reaction_10036038" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036035", "target": "reaction_10036038" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036035", "target": "reaction_10036042" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036035", "target": "reaction_10036220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZB4", "target": "species_10036035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033470", "target": "Q3SZB4" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036027", "target": "species_77322" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036027", "target": "species_113526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036027", "target": "species_77320" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036027", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036027", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77322", "target": "reaction_10036027" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77320", "target": "reaction_10036027" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036040", "target": "species_77341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036040", "target": "species_113526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036040", "target": "species_77339" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036040", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036040", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77341", "target": "reaction_10036040" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77339", "target": "reaction_10036040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036042", "target": "species_77308" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036042", "target": "species_113596" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036042", "target": "species_77343" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036042", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77308", "target": "reaction_10036042" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77343", "target": "reaction_10036042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036012", "target": "species_113526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036012", "target": "species_77252" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036012", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036012", "target": "species_77253" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036012", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77252", "target": "reaction_10036012" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77253", "target": "reaction_10036012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036021", "target": "species_113596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036021", "target": "species_77261" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036021", "target": "species_77255" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036021", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77261", "target": "reaction_10036021" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77255", "target": "reaction_10036021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036018", "target": "reaction_10036021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036018", "target": "reaction_10036023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08D92", "target": "species_10036018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013988", "target": "Q08D92" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036025", "target": "species_113526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036025", "target": "species_77251" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036025", "target": "species_73871" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036025", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036025", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77251", "target": "reaction_10036025" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_73871", "target": "reaction_10036025" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73871", "target": "reaction_10035417" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73871", "target": "reaction_10035372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036023", "target": "species_113596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036023", "target": "species_77272" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036023", "target": "species_77273" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036023", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77272", "target": "reaction_10036023" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_77273", "target": "reaction_10036023" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086403", "target": "species_29374" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086403", "target": "species_10086396" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_977314", "target": "reaction_10086403" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086393", "target": "reaction_10086403" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008382", "target": "species_10086393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008382", "target": "species_10086396" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008382", "target": "G3X6L0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008382", "target": "species_10038774" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086400", "target": "reaction_10086403" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003130", "target": "species_10086400" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036664", "target": "species_77343" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109994", "target": "reaction_10036664" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036215", "target": "reaction_10036664" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036215", "target": "reaction_10036218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTT7", "target": "species_10036215" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013144", "target": "F1MTT7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036218", "target": "species_77360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77358", "target": "reaction_10036218" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036220", "target": "species_109990" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036220", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109986", "target": "reaction_10036220" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075607", "target": "species_5690064" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075607", "target": "species_76194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5690044", "target": "reaction_10075607" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075600", "target": "reaction_10075607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QGE6", "target": "species_10075600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021731", "target": "F6QGE6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI69", "target": "species_10075600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075163", "target": "A0A3Q1MI69" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNW7", "target": "species_10075600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014753", "target": "E1BNW7" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075605", "target": "reaction_10075607" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075605", "target": "reaction_10085788" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024898", "target": "species_10075605" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024898", "target": "P02720" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076806", "target": "species_5695949" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076806", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5695946", "target": "reaction_10076806" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076803", "target": "reaction_10076806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080862", "target": "species_10076803" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042860", "target": "species_201034" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042860", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_549207", "target": "reaction_10042860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10042860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10051261" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10091490" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10075095" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10065673" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10047065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10083577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10083575" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200993", "target": "reaction_10074474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_201034", "target": "reaction_10042897" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042857", "target": "reaction_10042860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV3", "target": "species_10042857" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069870", "target": "A0A3Q1LMV3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK1", "target": "species_10042857" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021357", "target": "Q58DK1" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29508", "target": "reaction_10042860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29508", "target": "reaction_10051261" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29508", "target": "reaction_10051252" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042897", "target": "species_549207" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042897", "target": "species_201050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_201023", "target": "reaction_10042897" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042894", "target": "reaction_10042897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000217", "target": "species_10042894" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085185", "target": "species_10085183" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085181", "target": "reaction_10085185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015490", "target": "species_10085181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015490", "target": "A0A3S5ZPK2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085177", "target": "reaction_10085185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015231", "target": "species_10085177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015231", "target": "Q08E46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E46", "target": "species_10085183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPK2", "target": "species_10085183" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077001", "target": "species_5696412" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077001", "target": "species_162743" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192172", "target": "reaction_10077001" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696426", "target": "reaction_10077001" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076998", "target": "reaction_10077001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025081", "target": "species_10076998" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044657", "target": "species_266074" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044657", "target": "species_210382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_266013", "target": "reaction_10044657" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_416372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10045864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10045866" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266013", "target": "species_10046146" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_416372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10046259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10045864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10045866" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_266074", "target": "species_10046142" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044654", "target": "reaction_10044657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYJ3", "target": "species_10044654" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023658", "target": "F1MYJ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2D8", "target": "species_10044654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2D8", "target": "species_10071751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063999", "target": "G3N2D8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064482", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064482", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064482", "target": "species_2142740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2142740", "target": "reaction_10064503" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064581", "target": "species_2142772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265281", "target": "reaction_10064581" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064560", "target": "reaction_10064581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27479", "target": "species_10064560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27479", "target": "species_10064575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27479", "target": "species_10064562" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015911", "target": "P27479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015911", "target": "species_10064558" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064560" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064575" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064562" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064488" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10046998" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10043714" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10056699" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10056716" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10043930" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10069945" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10054401" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10034029" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10043945" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064897" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10064901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10066776" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10084494" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10033941" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10060261" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10083201" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10033985" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10057762" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10061734" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10061784" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10035351" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71067", "target": "species_10036905" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71067", "target": "reaction_10059181" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064503", "target": "species_2161582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064503", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064503", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064578", "target": "species_2142718" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064565" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064506" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29768", "target": "reaction_10064526" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064575", "target": "reaction_10064578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXW0", "target": "species_10064575" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011570", "target": "F1MXW0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064546", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064546", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064546", "target": "species_2142738" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064543", "target": "reaction_10064546" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064543", "target": "reaction_10090506" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064543", "target": "reaction_10090508" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064543", "target": "reaction_10090384" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064543", "target": "reaction_10090377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNI5", "target": "species_10064543" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNI5", "target": "species_10065205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNI5", "target": "species_10065208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018774", "target": "F1MNI5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064554", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064554", "target": "species_2142716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064554", "target": "species_111745" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2142790", "target": "reaction_10064554" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064551", "target": "reaction_10064554" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064551", "target": "reaction_10064567" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070793", "target": "species_10064551" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070793", "target": "species_10090371" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064565", "target": "species_2142811" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2142811", "target": "reaction_10064567" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064562", "target": "reaction_10064565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFA8", "target": "species_10064562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFA8", "target": "species_10064488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029240", "target": "F1MFA8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064567", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064567", "target": "species_2142678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064567", "target": "species_111745" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064534", "target": "species_2142745" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10064534" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10064506" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10090468" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10090472" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10090474" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10090392" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10090464" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064488", "target": "reaction_10064491" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076382", "target": "species_1498751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076382", "target": "species_29768" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693754", "target": "reaction_10076382" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693754", "target": "species_444560" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693754", "target": "species_10046257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693754", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693754", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5693754", "target": "species_6803725" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498751", "target": "reaction_10059150" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076379", "target": "reaction_10076382" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071864", "target": "species_10076379" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064506", "target": "species_2162031" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36190", "target": "species_2162031" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34784", "target": "species_2162031" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086336", "target": "species_8932804" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8932801", "target": "reaction_10086336" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086333", "target": "reaction_10086336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQD3", "target": "species_10086333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049076", "target": "Q1JQD3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIW1", "target": "species_10086333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020790", "target": "Q2KIW1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064521", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064521", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064521", "target": "species_2142739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2142739", "target": "species_215062" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064518", "target": "reaction_10064521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10064518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10064508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10064513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM10", "target": "species_10090705" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061300", "target": "F1MM10" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061300", "target": "species_10035962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10064518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10064508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10064513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10090705" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10090495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10038057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHN9", "target": "species_10071724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000094", "target": "F1MHN9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000094", "target": "species_10035858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNG1", "target": "species_10064518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNG1", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNG1", "target": "species_10064508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNG1", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNG1", "target": "species_10064513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075887", "target": "F1MNG1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075887", "target": "species_10044229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3N3", "target": "species_10064518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3N3", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3N3", "target": "species_10044257" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000051914", "target": "F1N3N3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW09", "target": "species_10064518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW09", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW09", "target": "species_10044257" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018202", "target": "M0QW09" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064526", "target": "species_29356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064526", "target": "species_2161753" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064526", "target": "species_29366" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34130", "target": "species_2161753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34130", "target": "species_215062" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34490", "target": "species_2161753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34490", "target": "species_215062" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34157", "target": "species_2161753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34157", "target": "species_215062" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064523", "target": "reaction_10064526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP79", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP79", "target": "species_10064513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP79", "target": "species_10044201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP79", "target": "species_10044262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP79", "target": "species_10090495" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027159", "target": "A0A3S5ZP79" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEU8", "target": "species_10064523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEU8", "target": "species_10064513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEU8", "target": "species_10044201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEU8", "target": "species_10090495" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008918", "target": "F1MEU8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065210", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065210", "target": "species_30138" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10065210" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10065213" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10065225" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10065216" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10090477" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10090504" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065205", "target": "reaction_10090510" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_549282", "target": "reaction_10065210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549282", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549282", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549282", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_549282", "target": "species_549250" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10065208", "target": "reaction_10065210" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064442", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064442", "target": "species_879535" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265283", "target": "reaction_10064442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265283", "target": "reaction_10064474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265283", "target": "reaction_10064479" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265283", "target": "reaction_10044599" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_879535", "target": "species_879566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_879535", "target": "species_879614" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041165", "target": "reaction_10064442" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041165", "target": "reaction_10064445" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041165", "target": "reaction_10072225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP71", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP71", "target": "species_10066244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP71", "target": "species_10041167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039350", "target": "E1BP71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW21", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW21", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028488", "target": "M0QW21" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG58", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG58", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038997", "target": "E1BG58" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038997", "target": "M0QW04" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW25", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW25", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030566", "target": "M0QW25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW04", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW04", "target": "species_10066244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW14", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QW14", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023326", "target": "M0QW14" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023326", "target": "G3X704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT58", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT58", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055749", "target": "F1MT58" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG2", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG2", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023297", "target": "Q3ZBG2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X704", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X704", "target": "species_10066244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK69", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK69", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056823", "target": "F1MK69" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P52897", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P52897", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024086", "target": "P52897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024086", "target": "P52898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNC0", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNC0", "target": "species_10066244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039362", "target": "F1MNC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P52898", "target": "species_10041165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P52898", "target": "species_10066244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064474", "target": "species_265287" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_265287", "target": "reaction_10064465" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064471", "target": "reaction_10064474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95L14", "target": "species_10064471" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025912", "target": "Q95L14" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065213", "target": "species_10065208" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9716714", "target": "reaction_10065213" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064445", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064445", "target": "species_2142710" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_879629", "target": "reaction_10064445" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064479", "target": "species_879629" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064476", "target": "reaction_10064479" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ9", "target": "species_10064476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGZ9", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022700", "target": "F1MGZ9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064465", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064465", "target": "species_879535" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064462", "target": "reaction_10064465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NG39", "target": "species_10064462" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084736", "target": "A0A3Q1NG39" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0T9", "target": "species_10064462" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043292", "target": "Q3T0T9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044599", "target": "species_265287" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044596", "target": "reaction_10044599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFK5", "target": "species_10044596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFK5", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFK5", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071669", "target": "A0A3Q1LFK5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIU3", "target": "species_10044596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIU3", "target": "species_10086682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIU3", "target": "species_10086684" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023908", "target": "A0A452DIU3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065225", "target": "species_10064543" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065225", "target": "species_2314690" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2314693", "target": "reaction_10065225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2314693", "target": "reaction_10065223" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065216", "target": "species_140357" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064452", "target": "species_2161634" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064449", "target": "reaction_10064452" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020065", "target": "species_10064449" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065223", "target": "species_10065221" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065223", "target": "species_2314690" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064511", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064511", "target": "species_113564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064511", "target": "species_2161639" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63995", "target": "species_2161639" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63994", "target": "species_2161639" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63579", "target": "species_2161639" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064508", "target": "reaction_10064511" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064531", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064531", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064531", "target": "species_2142780" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064528", "target": "reaction_10064531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3I8", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3I8", "target": "species_10064513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3I8", "target": "species_10035955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021785", "target": "F1N3I8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFI9", "target": "species_10064528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFI9", "target": "species_10064513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017246", "target": "F1MFI9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017246", "target": "species_10044239" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064516", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064516", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064516", "target": "species_2142836" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064513", "target": "reaction_10064516" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047033", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047033", "target": "species_389894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10047033" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10047042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10077835" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10047001" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10047019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10047022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10077435" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10041301" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113535", "target": "reaction_10041226" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389893", "target": "reaction_10047033" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389893", "target": "reaction_10047042" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047030", "target": "reaction_10047033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWZ7", "target": "species_10047030" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082299", "target": "A0A3Q1LWZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRF5", "target": "species_10047030" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRF5", "target": "species_10041223" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005472", "target": "F1MRF5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047056", "target": "species_193514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047056", "target": "species_390305" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047042", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047042", "target": "species_389894" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047039", "target": "reaction_10047042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFA4", "target": "species_10047039" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044120", "target": "A4IFA4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047044", "target": "species_389893" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389569", "target": "reaction_10047044" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041183", "target": "reaction_10047044" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041183", "target": "reaction_10041343" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041183", "target": "reaction_10041355" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041183", "target": "reaction_10041323" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041183", "target": "reaction_10041186" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029075", "target": "species_10041183" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077835", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077835", "target": "species_6787814" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787810", "target": "reaction_10077835" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077832", "target": "reaction_10077835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBW2", "target": "species_10077832" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000134", "target": "Q3ZBW2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077784", "target": "species_6786715" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077784", "target": "species_389556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193465", "target": "reaction_10077784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193465", "target": "reaction_10082889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193465", "target": "reaction_10076261" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6786723", "target": "reaction_10077784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113602", "target": "reaction_10077784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113602", "target": "reaction_10082889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113602", "target": "reaction_10076261" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077781", "target": "reaction_10077784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072961", "target": "species_10077781" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075576", "target": "species_5690539" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075576", "target": "species_193514" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5690520", "target": "reaction_10075576" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075573", "target": "reaction_10075576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6L4", "target": "species_10075573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPS3", "target": "species_10075573" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003683", "target": "A0A3S5ZPS3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBG0", "target": "species_10075573" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013568", "target": "E1BBG0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047053", "target": "species_353123" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047053", "target": "species_390246" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390241", "target": "reaction_10047053" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082880", "target": "species_6809800" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6809801", "target": "reaction_10082880" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082877", "target": "reaction_10082880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP28", "target": "species_10082877" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083505", "target": "A0A3Q1LP28" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054592", "target": "species_353123" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054592", "target": "species_389536" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_977323", "target": "reaction_10054592" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054589", "target": "reaction_10054592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005562", "target": "species_10054589" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047058", "target": "species_390260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_390394", "target": "reaction_10047058" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046704", "target": "reaction_10047058" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046704", "target": "reaction_10046707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ57", "target": "species_10046704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ57", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ57", "target": "species_10090768" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082889", "target": "species_389615" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082889", "target": "species_389556" }, { "type": "reactant", "sub_type": "", "source": "species_6809811", "target": "reaction_10082889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389615", "target": "reaction_10047001" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082886", "target": "reaction_10082889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L7", "target": "species_10082886" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008962", "target": "G3X6L7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047001", "target": "species_389594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047001", "target": "species_389583" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047001", "target": "species_389536" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389537", "target": "reaction_10047001" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046998", "target": "reaction_10047001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18778", "target": "species_10046998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18778", "target": "species_10090589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18778", "target": "species_10090591" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010126", "target": "O18778" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046984", "target": "species_193465" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046984", "target": "species_6811612" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046984", "target": "species_192305" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389636", "target": "reaction_10046984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192307", "target": "reaction_10046984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6811612", "target": "reaction_10046992" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192305", "target": "reaction_10082143" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046981", "target": "reaction_10046984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJ52", "target": "species_10046981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJ52", "target": "species_10076148" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJ52", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJ52", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070862", "target": "A0A3Q1LJ52" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046989", "target": "species_389593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046989", "target": "species_389615" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046989", "target": "species_389620" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389596", "target": "reaction_10046989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389573", "target": "reaction_10046989" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389573", "target": "reaction_10046992" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389620", "target": "reaction_10082143" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046986", "target": "reaction_10046989" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046986", "target": "reaction_10046992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078122", "target": "species_10046986" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078122", "target": "A0A3Q1M4C7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078122", "target": "species_10041314" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046992", "target": "species_389593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046992", "target": "species_389569" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046992", "target": "species_389620" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083389", "target": "species_4085425" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083389", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083389", "target": "species_5690558" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428139", "target": "reaction_10083389" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428139", "target": "reaction_10048882" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4085415", "target": "reaction_10083389" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083386", "target": "reaction_10083389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIA4", "target": "species_10083386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025820", "target": "Q2KIA4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051261", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051261", "target": "species_548812" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051261", "target": "species_76194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051258", "target": "reaction_10051261" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNQ7", "target": "species_10051258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067475", "target": "A6QNQ7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042961", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042961", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042961", "target": "species_200993" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042961", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3632881", "target": "reaction_10042961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3632881", "target": "reaction_10049351" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042958", "target": "reaction_10042961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZF6", "target": "species_10042958" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064114", "target": "Q1LZF6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPX2", "target": "species_10042958" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080693", "target": "A0A3Q1LPX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEX9", "target": "species_10042958" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022939", "target": "F1MEX9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022939", "target": "species_10049348" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074353", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074353", "target": "species_5676634" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5676631", "target": "reaction_10074353" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074350", "target": "reaction_10074353" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXJ1", "target": "species_10074350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046976", "target": "F1MXJ1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051252", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051252", "target": "species_548816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051252", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044985", "target": "species_351626" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044985", "target": "species_352169" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044985", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352186", "target": "reaction_10044985" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352186" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352169" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352036", "target": "species_352088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_352186" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_352169" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_8959775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_8932838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_8932842" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29612", "target": "reaction_10054585" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29612", "target": "reaction_10077758" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_427984" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29612", "target": "species_428003" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352186" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352169" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29642", "target": "species_352088" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29642", "target": "reaction_10033737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29642", "target": "reaction_10078529" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044982", "target": "reaction_10044985" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011214", "target": "species_10044982" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044955", "target": "species_352114" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352101", "target": "reaction_10044955" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352101", "target": "reaction_10044962" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_352101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_352114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:58045", "target": "species_508182" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_352088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57427", "target": "species_508182" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_174390", "target": "species_352088" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174390", "target": "reaction_10071924" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_352101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_352114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_352161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_352139" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351993", "target": "species_375481" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351993", "target": "reaction_10064346" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_352101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_352114" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29702", "target": "species_508182" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044952", "target": "reaction_10044955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072259", "target": "species_10044952" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045501", "target": "species_375781" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_375765", "target": "reaction_10045501" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_375765", "target": "reaction_10045494" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_375765" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_375781" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_8959775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_352128" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_352135" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_8932838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32551", "target": "species_8932842" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_375765" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_375781" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_8959775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_352128" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_352135" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_8932838" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_8932842" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_10091338" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113530", "target": "species_10091340" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113530", "target": "reaction_10033997" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045498", "target": "reaction_10045501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019060", "target": "species_10045498" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044978", "target": "species_352139" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352161", "target": "reaction_10044978" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_352161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_352139" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352006", "target": "species_375459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352006", "target": "reaction_10085381" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352030", "target": "species_352161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352030", "target": "species_352139" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352030", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352030", "target": "species_375481" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352030", "target": "reaction_10043986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352030", "target": "reaction_10043924" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044975", "target": "reaction_10044978" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012176", "target": "species_10044975" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044948", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044948", "target": "species_352048" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352051", "target": "reaction_10044948" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_375409" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_375414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379717", "target": "species_352088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351990", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351990", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351990", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351990", "target": "species_352088" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351990", "target": "reaction_10090155" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_111707", "target": "species_375459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10053266" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10053287" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10041737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10060252" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10060264" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10060234" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111707", "target": "reaction_10039865" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_352048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_379732", "target": "species_352088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18240", "target": "species_352051" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18240", "target": "species_352048" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044945", "target": "reaction_10044948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076418", "target": "species_10044945" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045494", "target": "species_375781" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045491", "target": "reaction_10045494" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009736", "target": "species_10045491" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088905", "target": "species_8959775" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8959777", "target": "reaction_10088905" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28229", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28229", "target": "species_8959775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113586", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113586", "target": "species_8959775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27747", "target": "species_8959777" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27747", "target": "species_8959775" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088902", "target": "reaction_10088905" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018163", "target": "species_10088902" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085384", "target": "species_113538" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352033", "target": "reaction_10085384" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352033", "target": "reaction_10049592" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085378", "target": "reaction_10085384" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085378", "target": "reaction_10085381" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011246", "target": "species_10085378" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045480", "target": "species_375481" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045480", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_375458", "target": "reaction_10045480" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375409" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_375414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_352091" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_352088" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29424", "target": "reaction_10078701" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29424", "target": "reaction_10085250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_428592" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29424", "target": "species_428632" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29424", "target": "reaction_10035345" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045477", "target": "reaction_10045480" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064818", "target": "species_10045477" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044971", "target": "species_352135" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352128", "target": "reaction_10044971" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044968", "target": "reaction_10044971" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070473", "target": "species_10044968" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044941", "target": "species_351982" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044941", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044941", "target": "species_352022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10044941" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10045487" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10049090" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10049583" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10054361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10054372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10048768" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10048740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10049592" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10049599" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10048601" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10048594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188972", "target": "reaction_10048478" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352007", "target": "reaction_10044941" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73590", "target": "species_352007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73590", "target": "species_351982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73590", "target": "species_375468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73590", "target": "species_375459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73590", "target": "reaction_10077758" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_352007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_351982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_10054358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_10054369" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_428592" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428571", "target": "species_428632" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352015", "target": "species_352007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352015", "target": "species_351982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352015", "target": "reaction_10060275" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48950", "target": "species_352007" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48950", "target": "species_351982" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044938", "target": "reaction_10044941" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067153", "target": "species_10044938" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045487", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045487", "target": "species_375459" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045487", "target": "species_352022" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_375468", "target": "reaction_10045487" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045484", "target": "reaction_10045487" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083685", "target": "species_10045484" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045473", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045473", "target": "species_375414" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_375409", "target": "reaction_10045473" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045470", "target": "reaction_10045473" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027731", "target": "species_10045470" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044962", "target": "species_352114" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044959", "target": "reaction_10044962" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015260", "target": "species_10044959" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044964", "target": "species_352088" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044964", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_352091", "target": "reaction_10044964" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044458", "target": "reaction_10044964" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044458", "target": "reaction_10044461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014749", "target": "species_10044458" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044934", "target": "species_29424" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_266029", "target": "reaction_10044934" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_266029", "target": "reaction_10049599" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044931", "target": "reaction_10044934" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016676", "target": "species_10044931" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039272", "target": "species_10039266" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039264", "target": "reaction_10039272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10039598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10041865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10041867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10040476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10040480" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP06", "target": "species_10040493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076924", "target": "A0A3Q1LP06" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039258", "target": "reaction_10039272" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039258", "target": "reaction_10039270" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067057", "target": "species_10039258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067057", "target": "A0A3Q1MJ18" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039266", "target": "reaction_10039270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10039598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10041865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ18", "target": "species_10041867" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040684", "target": "species_10039684" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039569", "target": "reaction_10040684" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039684", "target": "reaction_10039690" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039270", "target": "species_10039268" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088473", "target": "species_10088464" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088473", "target": "species_8931884" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088246", "target": "reaction_10088473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5X6", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5X6", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5X6", "target": "species_10088471" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080120", "target": "A0A3Q1N5X6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11116", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11116", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020080", "target": "P11116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP39", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP39", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000202", "target": "A6QP39" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG36", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG36", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009958", "target": "E1BG36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG25", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG25", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046533", "target": "E1BG25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUZ9", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUZ9", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026336", "target": "A4FUZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS36", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS36", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076629", "target": "A0A3Q1MS36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII7", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII7", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016252", "target": "A0A452DII7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5H2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5H2", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5H2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5H2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002297", "target": "F1N5H2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR5", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKR5", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013661", "target": "F1MKR5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3Y2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3Y2", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073105", "target": "A0A3Q1N3Y2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBZ6", "target": "species_10061327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027192", "target": "Q3ZBZ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLA8", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLA8", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044756", "target": "E1BLA8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05717", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05717", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078855", "target": "Q05717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20959", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20959", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053426", "target": "P20959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24591", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24591", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24591", "target": "species_10046619" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064194", "target": "P24591" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064194", "target": "species_10046617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95M18", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95M18", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95M18", "target": "species_10060771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95M18", "target": "species_10060769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004364", "target": "Q95M18" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004364", "target": "species_10060767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26892", "target": "species_10056196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019865", "target": "P26892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019865", "target": "species_10056094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPP2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPP2", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025803", "target": "F1MPP2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI67", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI67", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI67", "target": "species_10082179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI67", "target": "species_10082181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025557", "target": "F1MI67" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RJ01", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RJ01", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RJ01", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RJ01", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027753", "target": "F6RJ01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH1", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH1", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH1", "target": "species_10065431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH1", "target": "species_10065433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004992", "target": "Q2KJH1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10052876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10052886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10052903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10052905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10052874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6N3", "target": "species_10085162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6PX77", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6PX77", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064918", "target": "Q6PX77" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8P3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8P3", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002384", "target": "E1B8P3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ03", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ03", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028372", "target": "A0A452DJ03" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A5H1ZRH6", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A5H1ZRH6", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A5H1ZRH6", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A5H1ZRH6", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028238", "target": "A0A5H1ZRH6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10054645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10054647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10039322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10066236" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10054643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10054675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10054657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10039302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH06", "target": "species_10039310" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009019", "target": "E1BH06" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10054645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10054647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10039322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10066236" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10054643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10054675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10054657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10039302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK1", "target": "species_10039310" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045468", "target": "F1MVK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEA1", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEA1", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024433", "target": "F1MEA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMK4", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMK4", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMK4", "target": "species_10089685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMK4", "target": "species_10089687" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076179", "target": "A0A3Q1LMK4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076179", "target": "species_10089683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N348", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N348", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082028", "target": "G3N348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10075072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10075082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME65", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015804", "target": "F1ME65" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015804", "target": "species_10075088" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015804", "target": "species_10075070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAZ4", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAZ4", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005810", "target": "F1MAZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRR3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRR3", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074422", "target": "A0A3Q1LRR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01035", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000790", "target": "P01035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH94", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH94", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002508", "target": "F6QH94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHZ5", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHZ5", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003073", "target": "A0A452DHZ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE9", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE9", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020194", "target": "Q1LZE9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10045320" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10045322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01211", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087134", "target": "P01211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10037829" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10037921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10037945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJR8", "target": "species_10037919" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071014", "target": "A0A3Q1NJR8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071014", "target": "species_10037925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2L2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2L2", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063521", "target": "G3N2L2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEX5", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEX5", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072231", "target": "A0A3Q1MEX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPR4", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPR4", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044682", "target": "A6QPR4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044682", "target": "A6QQR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W6", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W6", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065790", "target": "G3N2W6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065790", "target": "G3X724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAS1", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAS1", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074235", "target": "A0A3Q1NAS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQR3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQR3", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X724", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X724", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NIX0", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NIX0", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078756", "target": "A0A3Q1NIX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ7", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ7", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016190", "target": "E1BHJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB94", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB94", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069263", "target": "A0A3Q1MB94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP86", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP86", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054074", "target": "A6QP86" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QSG5", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QSG5", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056456", "target": "F6QSG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIS3", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIS3", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085388", "target": "A0A3Q1LIS3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81644", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81644", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012138", "target": "P81644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD94", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD94", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027836", "target": "F1MD94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10089884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10089886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10090141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10090143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10072511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10072513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVS2", "target": "species_10073840" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069650", "target": "A0A3Q1LVS2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10069309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY30", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082437", "target": "A0A3Q1MY30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02817", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02817", "target": "species_10088464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016034", "target": "P02817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10069309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDK6", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057452", "target": "E1BDK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJF8", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJF8", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJF8", "target": "species_10065988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022706", "target": "E1BJF8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10088246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10088464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10069309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD77", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015881", "target": "F1MD77" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8931885", "target": "reaction_10088473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088471", "target": "reaction_10088473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJW4", "target": "species_10088471" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001439", "target": "F1MJW4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046621", "target": "species_10046619" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046613", "target": "reaction_10046621" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046613", "target": "reaction_10048429" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046617", "target": "reaction_10046621" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068959", "target": "species_10068957" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068951", "target": "reaction_10068959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064363", "target": "species_10068951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064363", "target": "G3N0Y4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068947", "target": "reaction_10068959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074434", "target": "species_10068947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074434", "target": "A0A3Q1NMK6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068943", "target": "reaction_10068959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002664", "target": "species_10068943" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002664", "target": "Q2KIG1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068955", "target": "reaction_10068959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018360", "target": "species_10068955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018360", "target": "G3X746" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X746", "target": "species_10068957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIG1", "target": "species_10068957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMK6", "target": "species_10068957" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0Y4", "target": "species_10068957" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061480", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061480", "target": "species_10057121" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061477", "target": "reaction_10061480" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061477", "target": "reaction_10061492" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10061477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10061466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10083475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10057697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10077599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10084842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10061456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCQ7", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029056", "target": "F1MCQ7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061469", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061469", "target": "species_10057130" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061466", "target": "reaction_10061469" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057692", "target": "species_10057690" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057688", "target": "reaction_10057692" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057690", "target": "reaction_10057695" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057695", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057695", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086415", "target": "species_10086413" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084846", "target": "reaction_10086415" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10084846", "target": "reaction_10084849" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068950", "target": "species_10084846" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068950", "target": "A0A3Q1M0B4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086408", "target": "reaction_10086415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0B4", "target": "species_10086413" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057139", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057139", "target": "species_10057136" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057134", "target": "reaction_10057139" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083483", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083483", "target": "species_10057132" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083483", "target": "species_10083480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083475", "target": "reaction_10083483" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057132", "target": "reaction_10083477" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057132", "target": "reaction_10077601" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057132", "target": "reaction_10084849" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057132", "target": "reaction_10061458" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083477", "target": "species_10083475" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083473", "target": "reaction_10083477" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057700", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057700", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057697", "target": "reaction_10057700" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077601", "target": "species_10077599" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077597", "target": "reaction_10077601" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085928", "target": "species_10077597" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085928", "target": "A0A3Q1N5P3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077599", "target": "reaction_10077605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5P3", "target": "species_10077599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5P3", "target": "species_10077603" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077605", "target": "species_10077603" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073537", "target": "reaction_10077605" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073537", "target": "reaction_10073547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10073537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10077603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10089943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10091860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10091862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10073535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD9", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083004", "target": "A0A3Q1LUD9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084849", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084849", "target": "species_10084842" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061458", "target": "species_10061456" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061454", "target": "reaction_10061458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069379", "target": "species_10061454" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069379", "target": "Q58D16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D16", "target": "species_10061456" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057740", "target": "species_10033408" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057740", "target": "species_10055232" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057740", "target": "species_10057726" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057737", "target": "reaction_10057740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI91", "target": "species_10057737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI91", "target": "species_10057709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI91", "target": "species_10057714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI91", "target": "species_10057730" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087037", "target": "Q2KI91" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087037", "target": "species_10055232" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIM6", "target": "species_10057737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033814", "target": "Q0IIM6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033814", "target": "species_10057726" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055232", "target": "reaction_10057744" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10055232", "target": "reaction_10057712" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057726", "target": "reaction_10057742" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057742", "target": "species_10057737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057709", "target": "reaction_10057742" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057744", "target": "species_10057714" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057066", "target": "reaction_10057744" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013790", "target": "species_10057066" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013790", "target": "A6QR62" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057714", "target": "reaction_10057719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR62", "target": "species_10057714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR62", "target": "species_10057716" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057712", "target": "species_10057709" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057719", "target": "species_10057716" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057719", "target": "species_10055232" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057735", "target": "species_10057732" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057735", "target": "species_10055232" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057730", "target": "reaction_10057735" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061492", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061492", "target": "species_10061466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061489", "target": "reaction_10061492" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066602", "target": "species_196931" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3165253", "target": "reaction_10066602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196931", "target": "reaction_10041799" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066599", "target": "reaction_10066602" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6I5", "target": "species_10066599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083852", "target": "A0A3Q1N6I5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9R1", "target": "species_10066599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084768", "target": "Q5E9R1" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_73524", "target": "reaction_10066602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73524", "target": "reaction_10041772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73524", "target": "reaction_10041781" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10047016" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10053358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_73524", "target": "species_10041762" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29386", "target": "reaction_10066602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29386", "target": "reaction_10041790" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041772", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041772", "target": "species_29386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041769", "target": "reaction_10041772" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081315", "target": "species_10041769" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041790", "target": "species_73524" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041790", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041787", "target": "reaction_10041790" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNS5", "target": "species_10041787" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061365", "target": "F1MNS5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041781", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041781", "target": "species_196931" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041778", "target": "reaction_10041781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8A0", "target": "species_10041778" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006339", "target": "E1B8A0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041799", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041799", "target": "species_73524" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041796", "target": "reaction_10041799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R223", "target": "species_10041796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025762", "target": "F6R223" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056185", "target": "species_10056180" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056185", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056174", "target": "reaction_10056185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10087778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10077866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10077868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10077872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089429" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10089422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10051816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10052167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10056311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME65", "target": "species_10056313" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "A0A3Q1ME65" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10051764" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10046556" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10087758" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10089359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10051758" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084342", "target": "species_10055960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ3", "target": "species_10056196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024587", "target": "E1BJQ3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024587", "target": "species_10056113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024587", "target": "species_10056098" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056180", "target": "reaction_10056188" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056180", "target": "reaction_10056205" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10056183", "target": "reaction_10056185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10056183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10051733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10083485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BEG9", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011106", "target": "Q9BEG9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011106", "target": "species_10051731" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056123", "target": "species_10056121" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056119", "target": "reaction_10056123" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056121", "target": "reaction_10056170" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056188", "target": "species_10056166" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056188", "target": "species_10051764" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056166", "target": "reaction_10056176" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056166", "target": "reaction_10056201" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056166", "target": "reaction_10056207" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051764", "target": "reaction_10056172" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056127", "target": "species_10056115" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056113", "target": "reaction_10056127" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056113", "target": "reaction_10091747" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056094", "target": "reaction_10056127" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056094", "target": "reaction_10056102" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056115", "target": "reaction_10056132" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10056125", "target": "reaction_10056127" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056176", "target": "species_10056174" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046556", "target": "reaction_10056176" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046556", "target": "reaction_10089331" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046556", "target": "reaction_10089480" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046556", "target": "reaction_10057854" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056178", "target": "species_10052345" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051766", "target": "reaction_10056178" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051766", "target": "reaction_10052347" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056201", "target": "species_10056190" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056190", "target": "reaction_10056194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056190", "target": "reaction_10056199" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056168", "target": "species_10056166" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056168", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056149", "target": "reaction_10056168" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056170", "target": "species_10056149" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056170", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056205", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056205", "target": "species_10056203" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056172", "target": "species_10051766" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056207", "target": "species_10056183" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051731", "target": "reaction_10056207" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051731", "target": "reaction_10083487" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056110", "target": "species_10056104" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049958", "target": "reaction_10056110" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049958", "target": "reaction_10056132" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049958", "target": "reaction_10049970" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056100", "target": "reaction_10056110" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056100", "target": "reaction_10056130" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10056108", "target": "reaction_10056110" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091747", "target": "species_10056125" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9715042", "target": "reaction_10091747" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056130", "target": "species_10056108" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056106", "target": "reaction_10056130" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056194", "target": "species_10056192" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10056194" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10057329" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10043832" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10040451" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10040386" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10040453" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10083632" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040359", "target": "reaction_10092126" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072559", "target": "species_10040359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072559", "target": "A0A3Q1LN00" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072559", "target": "species_10052267" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072559", "target": "species_10083635" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10056192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10052298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10052300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10052269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10052292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10053077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10053079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10073196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10040419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10092110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10092170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN00", "target": "species_10092180" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056132", "target": "species_10056117" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056199", "target": "species_10056196" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056199", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056102", "target": "species_10056100" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056098", "target": "reaction_10056102" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087338", "target": "species_10087336" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087334", "target": "reaction_10087338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWT5", "target": "species_10087334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWT5", "target": "species_10087336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023970", "target": "F1MWT5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023970", "target": "species_10083520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD32", "target": "species_10087334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD32", "target": "species_10087336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD32", "target": "species_10089593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023975", "target": "E1BD32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023975", "target": "species_10087332" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023975", "target": "species_10089589" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023975", "target": "species_10089587" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083514", "target": "reaction_10087338" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083514", "target": "reaction_10083522" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083514", "target": "reaction_10089595" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007489", "target": "species_10083514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007489", "target": "F1N3K3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3K3", "target": "species_10087336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3K3", "target": "species_10083516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3K3", "target": "species_10089593" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083522", "target": "species_10083516" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083510", "target": "reaction_10083522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX81", "target": "species_10083510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX81", "target": "species_10083516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065203", "target": "G3MX81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2N4", "target": "species_10083510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2N4", "target": "species_10083516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002696", "target": "F1N2N4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYY4", "target": "species_10083510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYY4", "target": "species_10083516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045402", "target": "F1MYY4" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10083520", "target": "reaction_10083522" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050024", "target": "species_10050007" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050024", "target": "species_10050005" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050024", "target": "species_10050017" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050024", "target": "species_10050015" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050013", "target": "reaction_10050024" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "species_10050013" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "species_10050007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "species_10050005" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "species_10050017" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "species_10050015" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072083", "target": "A0A3Q1MFA5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050007", "target": "reaction_10050011" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050005", "target": "reaction_10050011" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050021", "target": "reaction_10050024" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050011", "target": "species_10050009" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050009", "target": "reaction_10050028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA5", "target": "species_10050009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA5", "target": "species_10050026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA5", "target": "species_10089810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA5", "target": "species_10089816" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050028", "target": "species_10050026" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050026", "target": "reaction_10089812" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050026", "target": "reaction_10091439" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089595", "target": "species_10089593" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087332", "target": "reaction_10089595" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087332", "target": "reaction_10089591" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089597", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089597", "target": "species_10039514" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037699", "target": "reaction_10089597" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037699", "target": "reaction_10037723" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037699", "target": "reaction_10037702" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039514", "target": "reaction_10043753" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039514", "target": "reaction_10041333" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089591", "target": "species_10089589" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089591", "target": "species_10089587" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089625", "target": "species_10089623" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089617", "target": "reaction_10089625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "species_10089617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "species_10089623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "E1BLE5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "species_10083531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "species_10089814" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029311", "target": "species_10089619" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089819", "target": "species_10089816" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089810", "target": "reaction_10089819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE5", "target": "species_10089810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE5", "target": "species_10089816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE5", "target": "species_10083535" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089816", "target": "reaction_10089843" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089615", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089615", "target": "species_10089613" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053189", "target": "reaction_10089615" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053189", "target": "reaction_10067229" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023134", "target": "species_10053189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023134", "target": "species_10089613" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023134", "target": "E1BKP4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083537", "target": "species_10083535" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083527", "target": "reaction_10083537" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001371", "target": "species_10083527" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001371", "target": "F1MJ29" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083531", "target": "reaction_10083537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ29", "target": "species_10083535" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089843", "target": "species_10089814" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089843", "target": "species_10089617" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089843", "target": "species_10050026" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089621", "target": "species_10083531" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089619", "target": "reaction_10089621" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089619", "target": "reaction_10089812" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089812", "target": "species_10089810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049721", "target": "species_10049719" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049717", "target": "reaction_10049721" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087066", "target": "species_10049717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087066", "target": "A0A3Q1MKE9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049713", "target": "reaction_10049721" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML75", "target": "species_10049713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML75", "target": "species_10049719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML75", "target": "species_10091755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006938", "target": "F1ML75" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006938", "target": "species_10049707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIE7", "target": "species_10049713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIE7", "target": "species_10049719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008322", "target": "Q2KIE7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKE9", "target": "species_10049719" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043867", "target": "species_10043858" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043867", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043854", "target": "reaction_10043867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022183", "target": "species_10043854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022183", "target": "species_10043858" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022183", "target": "Q8WNW7" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043858", "target": "reaction_10043877" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043864", "target": "reaction_10043867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009995", "target": "species_10043864" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091757", "target": "species_10091755" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9681804", "target": "reaction_10091757" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049707", "target": "reaction_10091757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050428", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050428", "target": "species_10050425" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050418", "target": "reaction_10050428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMT8", "target": "species_10050418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMT8", "target": "species_10050425" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028115", "target": "Q1RMT8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028115", "target": "species_10050412" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ14", "target": "species_10050418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ14", "target": "species_10050425" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067567", "target": "A0A3Q1LQ14" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067567", "target": "species_10050416" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050420", "target": "species_10050418" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050416", "target": "reaction_10050420" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050412", "target": "reaction_10050420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051095", "target": "species_10051093" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051091", "target": "reaction_10051095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPF2", "target": "species_10051091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPF2", "target": "species_10051093" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081015", "target": "A0A3Q1LPF2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085017", "target": "species_10085015" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084951", "target": "reaction_10085017" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018087", "target": "species_10084951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018087", "target": "F1MTQ0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085013", "target": "reaction_10085017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10085013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10085015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10035231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10035252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10035250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10048700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10048712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10071014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10066768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10066770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10055866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68432", "target": "species_10055868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087179", "target": "P68432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10085013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10085015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10035231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10035252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10035250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10048700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10048712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10071014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10066768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10066770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10055866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P84227", "target": "species_10055868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079615", "target": "P84227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTQ0", "target": "species_10085015" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091731", "target": "species_10091729" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050577", "target": "reaction_10091731" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050577", "target": "reaction_10051196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027857", "target": "species_10050577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027857", "target": "E1BEL4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9678772", "target": "reaction_10091731" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10091729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10051187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10051192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10089255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10089289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEL4", "target": "species_10089264" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089251", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089251", "target": "species_10089248" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089244", "target": "reaction_10089251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10089244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10089248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10089240" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10089242" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPM3", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026608", "target": "E1BPM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7G0", "target": "species_10089244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7G0", "target": "species_10089248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7G0", "target": "species_10089240" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7G0", "target": "species_10089242" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026955", "target": "G3X7G0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G1", "target": "species_10089244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G1", "target": "species_10089248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G1", "target": "species_10089242" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072042", "target": "A0A3Q1M5G1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072042", "target": "species_10089234" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089253", "target": "species_10089242" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089234", "target": "reaction_10089253" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089240", "target": "reaction_10089253" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087787", "target": "species_10087785" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087772", "target": "reaction_10087787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQM6", "target": "species_10087772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQM6", "target": "species_10087785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074594", "target": "A0A3Q1MQM6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074594", "target": "species_10087768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10049938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10049944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK84", "target": "species_10087734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083936", "target": "A0A3Q1LK84" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083936", "target": "species_10087770" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083936", "target": "species_10049940" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049946", "target": "species_10049944" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049938", "target": "reaction_10049946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10049938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10049944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10089313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10089319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10089325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10089327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10089323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV0", "target": "species_10087760" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017046", "target": "A6QPV0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049944", "target": "reaction_10049970" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087726", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087726", "target": "species_10087723" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087711", "target": "reaction_10087726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10087711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10087723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10087791" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10049964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10049966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10087736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7S4", "target": "species_10087734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022524", "target": "A5D7S4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022524", "target": "species_10049962" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022524", "target": "species_10049968" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087774", "target": "species_10087772" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087770", "target": "reaction_10087774" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087768", "target": "reaction_10087774" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087793", "target": "species_10087791" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049962", "target": "reaction_10087793" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049970", "target": "species_10049966" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049964", "target": "reaction_10049970" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049966", "target": "reaction_10087671" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049966", "target": "reaction_10087783" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10049968", "target": "reaction_10049970" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087671", "target": "species_10049958" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087671", "target": "species_10049964" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087671", "target": "species_10049944" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10049940", "target": "reaction_10087671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087783", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087783", "target": "species_10087711" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087766", "target": "species_10087734" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087766", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087736", "target": "reaction_10087766" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089321", "target": "species_10089319" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089321", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089313", "target": "reaction_10089321" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089329", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089329", "target": "species_10089327" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089325", "target": "reaction_10089329" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089327", "target": "reaction_10089333" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089331", "target": "species_10089325" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089323", "target": "reaction_10089331" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087763", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087763", "target": "species_10087760" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087752", "target": "reaction_10087763" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089333", "target": "species_10087758" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089333", "target": "species_10089323" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087758", "target": "reaction_10089431" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087780", "target": "species_10087778" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087776", "target": "reaction_10087780" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049928", "target": "species_10049926" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049924", "target": "reaction_10049928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ0", "target": "species_10049924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ0", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ0", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ0", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ0", "target": "species_10087688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019945", "target": "F1MZJ0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049904", "target": "reaction_10049928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10049904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10049926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10087669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10087690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10087694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN4", "target": "species_10087688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005745", "target": "F1MSN4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049914", "target": "reaction_10049928" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087789", "target": "species_10049904" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087669", "target": "reaction_10087789" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087697", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087697", "target": "species_10087694" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087690", "target": "reaction_10087697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088498", "target": "species_10087690" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087674", "target": "reaction_10088498" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087688", "target": "reaction_10088498" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051194", "target": "species_10051192" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051187", "target": "reaction_10051194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVP1", "target": "species_10051187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVP1", "target": "species_10051192" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084967", "target": "A0A3Q1LVP1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084967", "target": "species_10047260" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051196", "target": "species_10051187" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047260", "target": "reaction_10051196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050527", "target": "species_10050136" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050134", "target": "reaction_10050527" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074166", "target": "species_10050134" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074166", "target": "A0A3Q1LQZ1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049950", "target": "reaction_10050527" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049950", "target": "reaction_10089736" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049950", "target": "reaction_10089455" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049950", "target": "reaction_10089506" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049950", "target": "reaction_10089446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10050136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10089255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10089289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQZ1", "target": "species_10089264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089736", "target": "species_10089734" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089732", "target": "reaction_10089736" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009944", "target": "species_10089732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009944", "target": "F1MTF9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTF9", "target": "species_10089734" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089363", "target": "species_10089361" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089359", "target": "reaction_10089363" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050619", "target": "species_10050617" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050571", "target": "reaction_10050619" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050569", "target": "reaction_10050619" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050569", "target": "reaction_10050623" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050569", "target": "reaction_10052337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051942" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10051917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10075103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXH7", "target": "species_10075099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011947", "target": "F1MXH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10051951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK34", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085850", "target": "A0A3Q1LK34" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051942" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10050561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10051917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10075103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB14", "target": "species_10075099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040022", "target": "A0A3Q1MB14" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040022", "target": "species_10050555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10050569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10050621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051942" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10050561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10051917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11052", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002054", "target": "P11052" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002054", "target": "species_10050559" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050617", "target": "reaction_10052254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE30", "target": "species_10050617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE30", "target": "species_10052252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054113", "target": "A2VE30" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050623", "target": "species_10050621" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052254", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052254", "target": "species_10052252" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052337", "target": "species_10052335" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052333", "target": "reaction_10052337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ7", "target": "species_10052333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ7", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ7", "target": "species_10060511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ7", "target": "species_10061081" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025510", "target": "E1BBJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJT8", "target": "species_10052333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJT8", "target": "species_10052335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJT8", "target": "species_10060511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJT8", "target": "species_10044032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJT8", "target": "species_10061081" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077857", "target": "A0A3Q1LJT8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077857", "target": "species_10043216" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052343", "target": "species_10052341" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052339", "target": "reaction_10052343" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10052339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10052341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10052238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10052732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10047046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M739", "target": "species_10044016" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077529", "target": "A0A3Q1M739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077529", "target": "species_10043836" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10052343" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10057323" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10057845" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10040451" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10036616" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10084194" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10046822" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035485", "target": "reaction_10047449" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089291", "target": "species_10089289" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089255", "target": "reaction_10089291" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089255", "target": "reaction_10089267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10089255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10089289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10089264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28028", "target": "species_10050130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084366", "target": "Q28028" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084366", "target": "species_10050124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10089255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10089289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10089305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10089309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10089264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M783", "target": "species_10050130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083836", "target": "A0A3Q1M783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083836", "target": "species_10050128" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089311", "target": "species_10089309" }, { "type": "reactant", "sub_type": "", "source": "species_10089307", "target": "reaction_10089311" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089305", "target": "reaction_10089311" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089267", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089267", "target": "species_10089264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089269", "target": "species_10050130" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050128", "target": "reaction_10089269" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050124", "target": "reaction_10089269" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089689", "target": "species_10089687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089685", "target": "reaction_10089689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL48", "target": "species_10089685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL48", "target": "species_10089687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL48", "target": "species_10049981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL48", "target": "species_10077841" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076664", "target": "A6QL48" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076664", "target": "species_10049979" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077839", "target": "reaction_10089689" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077839", "target": "reaction_10077843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016977", "target": "species_10077839" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016977", "target": "A7Z067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z067", "target": "species_10089687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z067", "target": "species_10077841" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089691", "target": "species_10089685" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089683", "target": "reaction_10089691" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049979", "target": "reaction_10089691" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049979", "target": "reaction_10049983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090027", "target": "species_10090025" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090023", "target": "reaction_10090027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069233", "target": "species_10090023" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069233", "target": "A0A3Q1LYB4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050140", "target": "reaction_10090027" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050140", "target": "reaction_10090031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017100", "target": "species_10050140" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017100", "target": "E1BGS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGS4", "target": "species_10090025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGS4", "target": "species_10090029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYB4", "target": "species_10090025" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049983", "target": "species_10049981" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049981", "target": "reaction_10077843" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090031", "target": "species_10090029" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077843", "target": "species_10077841" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10077945", "target": "species_10060767" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077723", "target": "species_10077721" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077719", "target": "reaction_10077723" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008311", "target": "species_10077719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008311", "target": "F1MGJ4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008311", "target": "species_10067208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008311", "target": "species_10046560" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008311", "target": "species_10067220" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077721", "target": "reaction_10077764" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10077721" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10077866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10077868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10077872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10077762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10067210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10067227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10067218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGJ4", "target": "species_10067214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077870", "target": "species_10077868" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077866", "target": "reaction_10077870" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077868", "target": "reaction_10077874" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077633", "target": "species_10077631" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049908", "target": "reaction_10077633" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077629", "target": "reaction_10077633" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025754", "target": "species_10077629" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025754", "target": "G3X7E9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7E9", "target": "species_10077631" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077874", "target": "species_10077872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077764", "target": "species_10077762" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052302", "target": "species_10052300" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052298", "target": "reaction_10052302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N016", "target": "species_10052298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N016", "target": "species_10052300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N016", "target": "species_10052296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N016", "target": "species_10039703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N016", "target": "species_10039709" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066024", "target": "G3N016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ32", "target": "species_10052298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ32", "target": "species_10052300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ32", "target": "species_10052296" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ32", "target": "species_10039579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ32", "target": "species_10039598" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007443", "target": "E1BQ32" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039707", "target": "reaction_10052302" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039707", "target": "reaction_10039711" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066818", "target": "species_10039707" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066818", "target": "A0A3Q1LXN8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXN8", "target": "species_10052300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXN8", "target": "species_10039709" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052323", "target": "species_10052298" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052267", "target": "reaction_10052323" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10052267", "target": "reaction_10083638" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052296", "target": "reaction_10052323" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052294", "target": "species_10052292" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052288", "target": "reaction_10052294" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052288", "target": "reaction_10075952" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052288", "target": "reaction_10073699" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052288", "target": "reaction_10074254" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052269", "target": "reaction_10052294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051962", "target": "species_10051960" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051923", "target": "reaction_10051962" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051923", "target": "reaction_10052240" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051949", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051949", "target": "species_10051946" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051942", "target": "reaction_10051949" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052735", "target": "species_10052732" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052238", "target": "reaction_10052735" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051966", "target": "species_10051921" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051964", "target": "reaction_10051966" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051921", "target": "reaction_10051936" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051921", "target": "reaction_10051954" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052321", "target": "species_10052319" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037660", "target": "reaction_10052321" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000289", "target": "species_10037660" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000289", "target": "P63103" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000289", "target": "species_10050402" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052317", "target": "reaction_10052321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10052319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10090832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10047517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10047515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10037670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10037672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10072612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10037662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10091031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10091019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10091021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10091025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10091027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63103", "target": "species_10050406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051936", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051936", "target": "species_10051923" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051933", "target": "reaction_10051936" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052240", "target": "species_10052238" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047046", "target": "reaction_10052240" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10047046", "target": "reaction_10052217" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051954", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051954", "target": "species_10051951" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052325", "target": "species_10050561" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050559", "target": "reaction_10052325" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050555", "target": "reaction_10052325" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050561", "target": "reaction_10052327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052327", "target": "species_10051917" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051911", "target": "reaction_10052327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089466", "target": "species_10089463" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089466", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089459", "target": "reaction_10089466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10089508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10050046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P5", "target": "species_10050048" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066507", "target": "A0A3Q1M5P5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066507", "target": "species_10050044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10089508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP0", "target": "species_10050048" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010919", "target": "A6QNP0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010919", "target": "species_10050032" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089530", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089530", "target": "species_10089450" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089527", "target": "reaction_10089530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZC4", "target": "species_10089527" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZC4", "target": "species_10089450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZC4", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZC4", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZC4", "target": "species_10089413" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063825", "target": "G3MZC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10089527" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10089450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10089413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G0", "target": "species_10050001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001456", "target": "E1B7G0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001456", "target": "species_10049999" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089450", "target": "reaction_10089453" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089523", "target": "species_10089490" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089523", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089520", "target": "reaction_10089523" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089427", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089427", "target": "species_10089424" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089417", "target": "reaction_10089427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10089417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10089424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10089415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10089422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Z4", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005749", "target": "E1B8Z4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005749", "target": "species_10052140" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089424", "target": "reaction_10089444" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089431", "target": "species_10089429" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089429", "target": "reaction_10089536" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089480", "target": "species_10089478" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089476", "target": "reaction_10089480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089478", "target": "reaction_10089516" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089453", "target": "species_10089413" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089453", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089413", "target": "reaction_10089540" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089516", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089516", "target": "species_10089513" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089513", "target": "reaction_10089542" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089455", "target": "species_10050038" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050036", "target": "reaction_10089455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001455", "target": "species_10050036" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001455", "target": "F1MJR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR4", "target": "species_10050038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR4", "target": "species_10089435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJR4", "target": "species_10089439" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089536", "target": "species_10089534" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089538", "target": "species_10089520" }, { "type": "reactant", "sub_type": "", "source": "species_10089518", "target": "reaction_10089538" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089484", "target": "reaction_10089538" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089442", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089442", "target": "species_10089439" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089435", "target": "reaction_10089442" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089506", "target": "species_10050001" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049999", "target": "reaction_10089506" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089540", "target": "species_10089417" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089415", "target": "reaction_10089540" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089444", "target": "species_10089413" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089444", "target": "species_10089422" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089511", "target": "species_10089476" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089511", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089508", "target": "reaction_10089511" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089446", "target": "species_10050046" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050044", "target": "reaction_10089446" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050046", "target": "reaction_10050054" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050054", "target": "species_10050048" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050032", "target": "reaction_10050054" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089542", "target": "species_10089476" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089542", "target": "species_10087758" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061449", "target": "species_10061443" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061434", "target": "reaction_10061449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X812", "target": "species_10061434" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X812", "target": "species_10061443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X812", "target": "species_10090832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X812", "target": "species_10044444" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050083", "target": "G3X812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050083", "target": "species_10090824" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050083", "target": "species_10044414" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10061447", "target": "reaction_10061449" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084118", "target": "species_10061447" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090834", "target": "species_10044414" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090824", "target": "reaction_10090834" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044414", "target": "reaction_10044446" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10090832", "target": "reaction_10090834" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078393", "target": "species_10038774" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078393", "target": "species_10078386" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078383", "target": "reaction_10078393" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:25650", "target": "species_10078383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10078383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6L0", "target": "species_10080513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076429", "target": "reaction_10078393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008936", "target": "species_10076429" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008936", "target": "species_10078386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008936", "target": "species_10076427" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008936", "target": "P20821" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078386", "target": "reaction_10078402" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078390", "target": "reaction_10078393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010820", "target": "species_10078390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052056", "target": "species_159549" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052056", "target": "species_113557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_379697", "target": "reaction_10052056" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159549", "target": "reaction_10076441" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159549", "target": "reaction_10076485" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159549", "target": "reaction_10038371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159549", "target": "reaction_10040682" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159549", "target": "reaction_10038382" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052053", "target": "reaction_10052056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG7", "target": "species_10052053" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010113", "target": "F1MLG7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047019", "target": "species_389678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047019", "target": "species_113575" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389822", "target": "reaction_10047019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389678", "target": "reaction_10047022" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047016", "target": "reaction_10047019" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047016", "target": "reaction_10047022" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC79", "target": "species_10047016" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061291", "target": "E1BC79" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078701", "target": "species_5359017" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078701", "target": "species_71285" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10078698", "target": "reaction_10078701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMP5", "target": "species_10078698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079667", "target": "A0A3Q1LMP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M678", "target": "species_10078698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080669", "target": "A0A3Q1M678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047022", "target": "species_389819" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047022", "target": "species_113575" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078366", "target": "species_10078359" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078366", "target": "species_10076429" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078353", "target": "reaction_10078366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079686", "target": "species_10078353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079686", "target": "species_10078359" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076427", "target": "reaction_10078366" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076427", "target": "reaction_10076441" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078363", "target": "reaction_10078366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005171", "target": "species_10078363" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077458", "target": "species_6784229" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077458", "target": "species_113553" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6784236", "target": "reaction_10077458" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113553", "target": "reaction_10033757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113553", "target": "reaction_10045029" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113553", "target": "reaction_10033728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033725", "target": "reaction_10077458" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033725", "target": "reaction_10033757" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033725", "target": "reaction_10033728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12344", "target": "species_10033725" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009440", "target": "P12344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078402", "target": "species_379705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078402", "target": "species_6793613" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078402", "target": "species_10076427" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6793610", "target": "reaction_10078402" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2162265", "target": "reaction_10078402" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10078399", "target": "reaction_10078402" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIP7", "target": "species_10078399" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019299", "target": "Q5BIP7" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:49883", "target": "species_10078399" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:49883", "target": "species_10086266" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076441", "target": "species_10076431" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076441", "target": "species_29376" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076431", "target": "reaction_10076450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20821", "target": "species_10076431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20821", "target": "species_10076443" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:14949", "target": "species_10076431" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076438", "target": "reaction_10076441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ1", "target": "species_10076438" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036700", "target": "E1BJQ1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076459", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076459", "target": "species_29362" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076459", "target": "species_10076427" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076443", "target": "reaction_10076459" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50746", "target": "species_10076443" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076456", "target": "reaction_10076459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N206", "target": "species_10076456" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033787", "target": "F1N206" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076450", "target": "species_5693978" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076450", "target": "species_5693984" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076450", "target": "species_10076443" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200671", "target": "reaction_10076450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693984", "target": "reaction_10081339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693984", "target": "reaction_10076485" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076447", "target": "reaction_10076450" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002992", "target": "species_10076447" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051737", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051737", "target": "species_10051722" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051716", "target": "reaction_10051737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051716", "target": "reaction_10051792" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051756" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLQ7", "target": "species_10051745" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066996", "target": "A0A3Q1LLQ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051756" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07353", "target": "species_10051776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016634", "target": "P07353" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051722", "target": "reaction_10051774" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10043836", "target": "reaction_10051737" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043836", "target": "reaction_10055958" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043836", "target": "reaction_10044018" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10051735", "target": "reaction_10051737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN0", "target": "species_10051735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN0", "target": "species_10051733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN0", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSN0", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005753", "target": "F1MSN0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091723", "target": "species_10051778" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9678984", "target": "reaction_10091723" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051743", "target": "reaction_10091723" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051743", "target": "reaction_10051780" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10051778", "target": "reaction_10051780" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051771", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051771", "target": "species_10051768" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051760", "target": "reaction_10051771" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051768", "target": "reaction_10052067" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051786", "target": "species_10051756" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051786", "target": "species_10051690" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051784", "target": "reaction_10051786" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051756", "target": "reaction_10051762" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051690", "target": "reaction_10051696" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051774", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051774", "target": "species_10051756" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051696", "target": "species_10051694" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051694", "target": "reaction_10051818" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051694", "target": "reaction_10055967" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052067", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052067", "target": "species_10051784" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052064", "target": "reaction_10052067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10052064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10070605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10048539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10048541" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10070655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10070612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10070626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10072004" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRR6", "target": "species_10072019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078659", "target": "A0A3Q1MRR6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078659", "target": "species_10041855" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078659", "target": "species_10041860" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078659", "target": "species_10070610" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078659", "target": "species_10050375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10052064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10069445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10069441" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10069452" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10069454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKC7", "target": "species_10048785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073084", "target": "A0A3Q1MKC7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M066", "target": "species_10052064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M066", "target": "species_10048785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071596", "target": "A0A3Q1M066" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051762", "target": "species_10051760" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051758", "target": "reaction_10051762" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051758", "target": "reaction_10052217" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051758", "target": "reaction_10052147" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051818", "target": "species_10051816" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051814", "target": "reaction_10051818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M137", "target": "species_10051814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M137", "target": "species_10051816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M137", "target": "species_10066355" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084456", "target": "A0A3Q1M137" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084456", "target": "A0A3Q1M2W5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084456", "target": "A0A3Q1M4Y4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084456", "target": "A0A3Q1MRS5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2W5", "target": "species_10051814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2W5", "target": "species_10051816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2W5", "target": "species_10066355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y4", "target": "species_10051814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y4", "target": "species_10051816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y4", "target": "species_10066355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS5", "target": "species_10051814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS5", "target": "species_10051816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS5", "target": "species_10066355" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051796", "target": "reaction_10051818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083334", "target": "species_10051796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083334", "target": "A0A3Q1ML58" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML58", "target": "species_10051816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055967", "target": "species_113550" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10055967", "target": "species_10055960" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10055964", "target": "reaction_10055967" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074168", "target": "species_10055964" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051792", "target": "species_10051735" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051733", "target": "reaction_10051792" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051780", "target": "species_10051745" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051702", "target": "reaction_10051780" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051745", "target": "reaction_10051748" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10051776", "target": "reaction_10051780" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051748", "target": "species_10051716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051748", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078682", "target": "species_10078680" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078678", "target": "reaction_10078682" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043330", "target": "species_10078678" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043330", "target": "E1BPK8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046864", "target": "reaction_10078682" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046864", "target": "reaction_10046868" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046864", "target": "reaction_10084356" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M422", "target": "species_10046864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M422", "target": "species_10078680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M422", "target": "species_10046866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M422", "target": "species_10078564" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M422", "target": "species_10084354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066459", "target": "A0A3Q1M422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066459", "target": "species_10046858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZF8", "target": "species_10046864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZF8", "target": "species_10078680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZF8", "target": "species_10078672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZF8", "target": "species_10046866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZF8", "target": "species_10084354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074444", "target": "A0A3Q1MZF8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074444", "target": "species_10046862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPK8", "target": "species_10078680" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078674", "target": "species_10078672" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046862", "target": "reaction_10078674" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078670", "target": "reaction_10078674" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064547", "target": "species_10078670" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064547", "target": "G3N3T6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10078672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10090663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10090720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10090724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10090654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3T6", "target": "species_10090673" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046868", "target": "species_10046866" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046854", "target": "reaction_10046868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH3", "target": "species_10046854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH3", "target": "species_10046866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073078", "target": "A0A3Q1MBH3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5L6", "target": "species_10046854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5L6", "target": "species_10046866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081984", "target": "A0A3Q1M5L6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ22", "target": "species_10046854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ22", "target": "species_10046866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075872", "target": "A0A3Q1LQ22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5X2", "target": "species_10046854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5X2", "target": "species_10046866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069454", "target": "A0A3Q1M5X2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078566", "target": "species_10078564" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078562", "target": "reaction_10078566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5L8", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5L8", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015639", "target": "F1N5L8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJJ9", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJJ9", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054494", "target": "F1MJJ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X9", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X9", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013364", "target": "E1B8X9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2N1", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2N1", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072588", "target": "G3N2N1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSM8", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSM8", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005757", "target": "F1MSM8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N513", "target": "species_10078562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N513", "target": "species_10078564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022827", "target": "F1N513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046858", "target": "reaction_10078566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034944", "target": "species_73566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034944", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73578", "target": "reaction_10034944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73578", "target": "reaction_10036903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73578", "target": "reaction_10034041" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10041824" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10041808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10041831" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10035354" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10036909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10035435" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73566", "target": "reaction_10035444" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034941", "target": "reaction_10034944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ58", "target": "species_10034941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ58", "target": "species_10034933" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026261", "target": "Q2HJ58" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036903", "target": "species_73566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036903", "target": "species_109386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_110644", "target": "reaction_10036903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_500101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_500125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_500222" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_500088" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_500199" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_6788778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109386", "target": "species_6788802" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034933", "target": "reaction_10036903" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076792", "target": "species_5694580" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076792", "target": "species_5694567" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5694568", "target": "reaction_10076792" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076789", "target": "reaction_10076792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022154", "target": "species_10076789" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059002", "target": "species_1498738" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059002", "target": "species_1524021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500581", "target": "reaction_10059002" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500581", "target": "reaction_10059004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500581", "target": "reaction_10084526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500581", "target": "reaction_10058980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500581", "target": "reaction_10059073" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498738", "target": "reaction_10058899" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058940", "target": "reaction_10059002" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058940", "target": "reaction_10058943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMD6", "target": "species_10058940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMD6", "target": "species_10084523" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMD6", "target": "species_10058972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMD6", "target": "species_10058987" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078451", "target": "A0A3Q1NMD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR65", "target": "species_10058940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR65", "target": "species_10058855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR65", "target": "species_10058868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR65", "target": "species_10058931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR65", "target": "species_10058987" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067227", "target": "A0A3Q1LR65" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR5", "target": "species_10058940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR5", "target": "species_10058977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR5", "target": "species_10059023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR5", "target": "species_10058868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078489", "target": "A0A3Q1LYR5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10059023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10059011" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG30", "target": "species_10058987" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003576", "target": "F1MG30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10058940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10058977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10058972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10058868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10059011" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNU5", "target": "species_10058987" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006775", "target": "F1MNU5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059853", "target": "species_1602372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059853", "target": "species_1602366" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602366", "target": "species_10071386" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059853" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059851" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059860" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059849" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059847" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059844", "target": "reaction_10059858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSG5", "target": "species_10059844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005791", "target": "F1MSG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGU4", "target": "species_10059844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028684", "target": "E1BGU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ2", "target": "species_10059844" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ2", "target": "species_10058967" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ2", "target": "species_10058905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ2", "target": "species_10059808" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ2", "target": "species_10084704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007570", "target": "Q56JZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFE1", "target": "species_10059844" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFE1", "target": "species_10058855" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078105", "target": "A0A3Q1MFE1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7L0", "target": "species_10059844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020263", "target": "A5D7L0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNU5", "target": "species_10059844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080344", "target": "A0A3Q1MNU5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5P6", "target": "species_10059844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077544", "target": "A0A3Q1M5P6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059004", "target": "species_1498738" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059004", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058967", "target": "reaction_10059004" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058967", "target": "reaction_10058970" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE78", "target": "species_10058967" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017658", "target": "E1BE78" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084526", "target": "species_5694568" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084526", "target": "species_6814253" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10084526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10059114" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10086064" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10085808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10058970" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10058990" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10058996" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426925", "target": "reaction_10059121" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6814253", "target": "reaction_10083211" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084523", "target": "reaction_10084526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058899", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058899", "target": "species_1500581" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058882", "target": "reaction_10058899" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058882", "target": "reaction_10058885" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JL05", "target": "species_10058882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JL05", "target": "species_10058806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054491", "target": "G8JL05" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054491", "target": "species_10058800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH02", "target": "species_10058882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH02", "target": "species_10058806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010729", "target": "F1MH02" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058885", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058885", "target": "species_1500581" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498729", "target": "reaction_10058885" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058980", "target": "species_1498729" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058980", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058977", "target": "reaction_10058980" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046888", "target": "species_10046884" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046882", "target": "reaction_10046888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2W6", "target": "species_10046882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2W6", "target": "species_10046884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083184", "target": "A0A3Q1M2W6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C5NU11", "target": "species_10046882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C5NU11", "target": "species_10046884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008067", "target": "C5NU11" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046872", "target": "reaction_10046888" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046872", "target": "reaction_10091743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079165", "target": "species_10046872" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079165", "target": "A0A3Q1MQR6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQR6", "target": "species_10046884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQR6", "target": "species_10046886" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10046886", "target": "reaction_10046888" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091743", "target": "species_10046886" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9679406", "target": "reaction_10091743" }, { "type": "product", "sub_type": "other", "source": "reaction_10064439", "target": "species_2161185" }, { "type": "reactant", "sub_type": "other", "source": "species_2161525", "target": "reaction_10064439" }, { "type": "reactant", "sub_type": "other", "source": "species_2161185", "target": "reaction_10064584" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051266", "target": "reaction_10064439" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051266", "target": "reaction_10051269" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051266", "target": "reaction_10051286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBE0", "target": "species_10051266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004059", "target": "A7MBE0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064584", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064584", "target": "species_2162081" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064584", "target": "species_73473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034181", "target": "reaction_10064584" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZP8", "target": "species_10034181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZP8", "target": "species_10071670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZP8", "target": "species_10034203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009185", "target": "F1MZP8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075063", "target": "species_10075061" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050549", "target": "reaction_10075063" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086241", "target": "species_10086239" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10086241" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10087862" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10088012" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10086231" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10088490" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084943", "target": "reaction_10084947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10084943" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "A0A3Q1MYL2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10086584" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10088485" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10086577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10088478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070567", "target": "species_10088480" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086237", "target": "reaction_10086241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF28", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF28", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF28", "target": "species_10044424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF28", "target": "species_10044444" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078064", "target": "A0A3Q1MF28" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQE0", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQE0", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQE0", "target": "species_10071260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQE0", "target": "species_10044444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQE0", "target": "species_10044724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010697", "target": "Q1JQE0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010697", "target": "species_10044442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ41", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ41", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ41", "target": "species_10044444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ41", "target": "species_10044724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004696", "target": "Q3SZ41" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004696", "target": "species_10044410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10076107" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10076109" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10071062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10053054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10056086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10053056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10056076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10087908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10087887" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10087897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10083070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10083074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10066722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10072547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D6", "target": "species_10084893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021556", "target": "E1B8D6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021556", "target": "species_10053052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10076107" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10076109" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10071062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10044434" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10044444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10091086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT2", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075969", "target": "A0A3Q1MLT2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10086237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10053054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10056086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10053056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10056076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10044444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10047805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10091182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD32", "target": "species_10084893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005092", "target": "F1MD32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005092", "target": "species_10044438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10086239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10087860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10087908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10087995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10087887" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10087897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10084945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10088001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10088003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10088010" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10086229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYL2", "target": "species_10086579" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072913", "target": "species_10043237" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072913", "target": "species_10065265" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072911", "target": "reaction_10072913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10090673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10072917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10044467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10044463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10056311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10056313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10043239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10043259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10066099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10044022" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYF9", "target": "species_10061110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023383", "target": "F1MYF9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023383", "target": "species_10043237" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023383", "target": "species_10061098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023383", "target": "species_10043197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023383", "target": "species_10043234" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065265", "target": "reaction_10072946" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065265", "target": "reaction_10073140" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065265", "target": "reaction_10073014" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072944", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072944", "target": "species_10072911" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072941", "target": "reaction_10072944" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072946", "target": "species_10072941" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061098", "target": "reaction_10072946" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061098", "target": "reaction_10072933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061098", "target": "reaction_10072931" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061098", "target": "reaction_10072937" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073152", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073152", "target": "species_10073149" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073138", "target": "reaction_10073152" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073149", "target": "reaction_10073156" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073140", "target": "species_10073138" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073156", "target": "species_10073154" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073154", "target": "reaction_10073159" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073159", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073159", "target": "species_10039728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073234", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073234", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065273", "target": "reaction_10073234" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073145", "target": "species_10065269" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073145", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073142", "target": "reaction_10073145" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065269", "target": "reaction_10087376" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065269", "target": "reaction_10073244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073019", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073019", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073016", "target": "reaction_10073019" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073147", "target": "species_10073142" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065267", "target": "reaction_10073147" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065267", "target": "reaction_10073021" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073021", "target": "species_10073016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087376", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087376", "target": "species_10039728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073011", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073011", "target": "species_10065267" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073006", "target": "reaction_10073011" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10073009", "target": "reaction_10073011" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073014", "target": "species_10073006" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072959", "target": "reaction_10073014" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072959", "target": "reaction_10073031" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072959", "target": "reaction_10072979" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072959", "target": "reaction_10073083" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072959", "target": "reaction_10084330" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10062984", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062984", "target": "species_10062971" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062948", "target": "reaction_10062984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX8", "target": "species_10061327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011475", "target": "F1MZX8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MER7", "target": "species_10069410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10085701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5R3", "target": "species_10085751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082452", "target": "A0A3Q1N5R3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTY7", "target": "species_10061327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085269", "target": "A0A3Q1LTY7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10048931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10048933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10085701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ29", "target": "species_10085751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082766", "target": "A0A3Q1LZ29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10062948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10062971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10063007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10060650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10060664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10060394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10085701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS1", "target": "species_10085751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020125", "target": "E1BKS1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062981", "target": "reaction_10062984" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062981", "target": "reaction_10063010" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4L2", "target": "species_10062981" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080227", "target": "A8E4L2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063610", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063610", "target": "species_10063068" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063045", "target": "reaction_10063610" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063068", "target": "reaction_10063633" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063068", "target": "reaction_10063586" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063607", "target": "reaction_10063610" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086518", "target": "species_10063607" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063633", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063633", "target": "species_10063091" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063630", "target": "reaction_10063633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD21", "target": "species_10063630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085321", "target": "Q0VD21" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B729", "target": "species_10063630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025630", "target": "E1B729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKQ1", "target": "species_10063630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023123", "target": "E1BKQ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNJ7", "target": "species_10063630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044024", "target": "E1BNJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP03", "target": "species_10063630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010350", "target": "E1BP03" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063216", "target": "species_10063214" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063132", "target": "reaction_10063216" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063603", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063603", "target": "species_10063130" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063114", "target": "reaction_10063603" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063600", "target": "reaction_10063603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS54", "target": "species_10063600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078465", "target": "A0A3Q1LS54" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTK3", "target": "species_10063600" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075020", "target": "A0A3Q1LTK3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063010", "target": "species_10062948" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063010", "target": "species_2022890" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2022884", "target": "reaction_10063010" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2022884", "target": "reaction_10088580" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2022884", "target": "reaction_10083873" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2022884", "target": "reaction_10083876" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063007", "target": "reaction_10063010" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063586", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063586", "target": "species_10063091" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063583", "target": "reaction_10063586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCB5", "target": "species_10063583" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009799", "target": "Q0VCB5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051589", "target": "species_109402" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051589", "target": "species_744234" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_744229", "target": "reaction_10051589" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735698", "target": "reaction_10051589" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051584", "target": "reaction_10051589" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051584", "target": "reaction_10051587" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026562", "target": "species_10051584" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026562", "target": "A2VE55" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084090", "target": "species_10084088" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084086", "target": "reaction_10084090" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084086", "target": "reaction_10084102" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084084", "target": "reaction_10084090" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011655", "target": "species_10084084" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011655", "target": "F6Q0F9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011655", "target": "species_10084093" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084088", "target": "reaction_10084096" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q0F9", "target": "species_10084088" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084096", "target": "species_10084086" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084096", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084096", "target": "species_10084093" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076112", "target": "species_10036828" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076112", "target": "species_10076109" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076107", "target": "reaction_10076112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUE2", "target": "species_10076107" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUE2", "target": "species_10076109" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080652", "target": "A0A3Q1MUE2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10067694" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10072713" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10086724" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10092287" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10088490" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10040542" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10057821" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10077396" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10081541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10073302" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10077591" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036828", "target": "reaction_10073290" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076119", "target": "species_10039537" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039539", "target": "reaction_10076119" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039539", "target": "reaction_10071524" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039539", "target": "reaction_10075397" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039539", "target": "reaction_10073690" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076116", "target": "reaction_10076119" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046166", "target": "species_10076116" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046166", "target": "Q17QP9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089947", "target": "species_10089945" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089943", "target": "reaction_10089947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10089943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10068931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10068937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHF1", "target": "species_10069297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075877", "target": "A0A3Q1LHF1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075877", "target": "species_10068927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSX9", "target": "species_10089943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSX9", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSX9", "target": "species_10073489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSX9", "target": "species_10073491" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073284", "target": "A0A3Q1LSX9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM61", "target": "species_10089943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM61", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM61", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM61", "target": "species_10089928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075730", "target": "A0A3Q1LM61" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10089943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10073802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10073804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10073784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV55", "target": "species_10073794" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079495", "target": "A0A3Q1LV55" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073483", "target": "reaction_10089947" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073483", "target": "reaction_10092364" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073483", "target": "reaction_10089952" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073483", "target": "reaction_10073503" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073483", "target": "reaction_10073493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073483" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10089945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10092362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10089932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10073505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10047839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMJ6", "target": "species_10047841" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018998", "target": "Q1RMJ6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092364", "target": "species_10092362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089937", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089937", "target": "species_10073483" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089932", "target": "reaction_10089937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089934", "target": "reaction_10089937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUW4", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUW4", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUW4", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069851", "target": "A0A3Q1LUW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6F4", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6F4", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6F4", "target": "species_10047819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6F4", "target": "species_10047821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072165", "target": "A0A3Q1N6F4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10090327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10090084" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10070647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10070649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10066099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQP9", "target": "species_10069154" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086853", "target": "A0A3Q1MQP9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086853", "target": "species_10048073" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086853", "target": "species_10049423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10090327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10090095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10090084" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRV3", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083879", "target": "A0A3Q1MRV3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083879", "target": "species_10041467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFQ5", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFQ5", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFQ5", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFQ5", "target": "species_10037327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066417", "target": "A0A3Q1LFQ5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066417", "target": "species_10037325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN47", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN47", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN47", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN47", "target": "species_10047550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081099", "target": "A0A3Q1MN47" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081099", "target": "species_10047548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT3", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT3", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT3", "target": "species_10069141" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074225", "target": "A0A3Q1LKT3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074225", "target": "species_10069135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNE2", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNE2", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNE2", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077218", "target": "A0A3Q1LNE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ45", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ45", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078928", "target": "A0A3Q1LQ45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G5", "target": "species_10089934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G5", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G5", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002373", "target": "F1N2G5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB21", "target": "species_10089934" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017829", "target": "F1MB21" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089952", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089952", "target": "species_10089932" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089949", "target": "reaction_10089952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10089949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10089146" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10091992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10092016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM23", "target": "species_10092018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038690", "target": "E1BM23" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092392", "target": "species_10092390" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092388", "target": "reaction_10092392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK69", "target": "species_10092388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK69", "target": "species_10092390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK69", "target": "species_10090323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK69", "target": "species_10090325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK69", "target": "species_10090347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079280", "target": "A5PK69" }, { "type": "reactant", "sub_type": "", "source": "species_10092384", "target": "reaction_10092392" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090330", "target": "species_10090325" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090330", "target": "species_29420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090323", "target": "reaction_10090330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090323", "target": "reaction_10090349" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090325", "target": "reaction_10092394" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090325", "target": "reaction_10090339" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090327", "target": "reaction_10090330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10090327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10090095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10090084" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10047819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10047821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLS2", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061086", "target": "F1MLS2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092394", "target": "species_10092388" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090349", "target": "species_10090347" }, { "type": "reactant", "sub_type": "", "source": "species_10090341", "target": "reaction_10090349" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090339", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090339", "target": "species_10090323" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090336", "target": "reaction_10090339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6V1", "target": "species_10090336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6V1", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003400", "target": "F1N6V1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF90", "target": "species_10090336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061453", "target": "A4IF90" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089930", "target": "species_10089928" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089926", "target": "reaction_10089930" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10090113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFP5", "target": "species_10059111" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068010", "target": "A0A3Q1MFP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJH7", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJH7", "target": "species_10089928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJH7", "target": "species_10073575" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073587", "target": "A0A3Q1LJH7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073587", "target": "species_10073573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X696", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X696", "target": "species_10089928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001346", "target": "G3X696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBT6", "target": "species_10089926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBT6", "target": "species_10089928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046371", "target": "F1MBT6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089149", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089149", "target": "species_10037313" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089146", "target": "reaction_10089149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DB1", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039899", "target": "Q08DB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGB9", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052139", "target": "F1MGB9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q1", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076617", "target": "A0A3Q1M2Q1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI70", "target": "species_10089146" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI70", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI70", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI70", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI70", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027682", "target": "E1BI70" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYQ4", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011665", "target": "F1MYQ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXE8", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066138", "target": "G3MXE8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM3", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035838", "target": "E1BIM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV18", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020147", "target": "A4FV18" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGT5", "target": "species_10089146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075956", "target": "A0A3Q1LGT5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089888", "target": "species_10089886" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089862", "target": "reaction_10089888" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089884", "target": "reaction_10089888" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089011", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089011", "target": "species_10037315" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089008", "target": "reaction_10089011" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH51", "target": "species_10089008" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005514", "target": "E1BH51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ24", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ24", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007450", "target": "E1BQ24" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8D9", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8D9", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071999", "target": "A0A3Q1M8D9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDY4", "target": "species_10089008" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082024", "target": "E1BDY4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJS1", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJS1", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068893", "target": "A0A3Q1LJS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5A2", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5A2", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067575", "target": "A0A3Q1N5A2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA88", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA88", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069507", "target": "A0A3Q1MA88" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD11", "target": "species_10089008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD11", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD11", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081804", "target": "A0A3Q1MD11" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089890", "target": "species_10089862" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089860", "target": "species_10089858" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089854", "target": "reaction_10089860" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089854", "target": "reaction_10090125" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007933", "target": "species_10089854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007933", "target": "A0A452DIS6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIS6", "target": "species_10089858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIS6", "target": "species_10090123" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090125", "target": "species_10090123" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090093", "target": "reaction_10090125" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090093", "target": "reaction_10090098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10090093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10090123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10090117" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10090143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10037305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10090113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10072505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10072513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10049418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI2", "target": "species_10049420" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000453", "target": "Q1RMI2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090145", "target": "species_10090143" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090117", "target": "reaction_10090145" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090141", "target": "reaction_10090145" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090115", "target": "species_10090113" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090111", "target": "reaction_10090115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX25", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX25", "target": "species_10090113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069555", "target": "A0A3Q1LX25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWX5", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWX5", "target": "species_10090113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWX5", "target": "species_10090084" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWX5", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWX5", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081739", "target": "A0A3Q1LWX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT94", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT94", "target": "species_10090113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085032", "target": "A0A3Q1MT94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR1", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR1", "target": "species_10090113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR1", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR1", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001190", "target": "F1MTR1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNR4", "target": "species_10090111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNR4", "target": "species_10090113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083570", "target": "A0A3Q1NNR4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037305", "target": "reaction_10090115" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037305", "target": "reaction_10090103" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037305", "target": "reaction_10090119" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090098", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090098", "target": "species_10037305" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090095", "target": "reaction_10090098" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090103", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090103", "target": "species_10090093" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090100", "target": "reaction_10090103" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090119", "target": "species_10090117" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090089", "target": "species_10073712" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037299", "target": "reaction_10090089" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037299", "target": "reaction_10090077" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037299", "target": "reaction_10092382" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037299", "target": "reaction_10090082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037299", "target": "reaction_10092370" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10037299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10073712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10073714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10090075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10092374" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10092378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10090033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10092368" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TU25", "target": "species_10073729" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014666", "target": "Q9TU25" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073712", "target": "reaction_10090091" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073712", "target": "reaction_10073716" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090091", "target": "species_10073714" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073714", "target": "reaction_10073731" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073714", "target": "reaction_10077921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090077", "target": "species_10090075" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090073", "target": "reaction_10090077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFB9", "target": "species_10090073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFB9", "target": "species_10090075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFB9", "target": "species_10063365" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFB9", "target": "species_10059111" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080368", "target": "A0A3Q1MFB9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092380", "target": "species_10092378" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092374", "target": "reaction_10092380" }, { "type": "reactant", "sub_type": "", "source": "species_10092376", "target": "reaction_10092380" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092382", "target": "species_10092374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090082", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090082", "target": "species_10090033" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090033", "target": "reaction_10090087" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090079", "target": "reaction_10090082" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092370", "target": "species_10092368" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090087", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090087", "target": "species_10037299" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090084", "target": "reaction_10090087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M7", "target": "species_10090084" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071096", "target": "A0A3Q1M4M7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKN5", "target": "species_10090084" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080659", "target": "A0A3Q1MKN5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090203", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090203", "target": "species_10090191" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090193", "target": "reaction_10090203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV20", "target": "species_10090193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV20", "target": "species_10090191" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022858", "target": "A4FV20" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090191", "target": "reaction_10090198" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090200", "target": "reaction_10090203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNA6", "target": "species_10090200" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002840", "target": "E1BNA6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090198", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090198", "target": "species_10090193" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090195", "target": "reaction_10090198" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091994", "target": "species_10091992" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091990", "target": "reaction_10091994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB2", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB2", "target": "species_10091992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB2", "target": "species_10092016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB2", "target": "species_10092018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010671", "target": "E1BLB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPM3", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPM3", "target": "species_10091992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068488", "target": "A0A3Q1LPM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C5", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C5", "target": "species_10091992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002375", "target": "F1N4C5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6F8", "target": "species_10091990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6F8", "target": "species_10091992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6F8", "target": "species_10092016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6F8", "target": "species_10092018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077393", "target": "A0A3Q1M6F8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091948", "target": "reaction_10091994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUP6", "target": "species_10091948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUP6", "target": "species_10091992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009719", "target": "F1MUP6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009719", "target": "species_10091946" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092022", "target": "species_10091948" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091946", "target": "reaction_10092022" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091832", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091832", "target": "species_10091829" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091827", "target": "reaction_10091832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA1", "target": "species_10091827" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA1", "target": "species_10091829" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA1", "target": "species_10091862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA1", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA1", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046161", "target": "Q3SZA1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091829", "target": "reaction_10091864" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091829", "target": "reaction_10091921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091864", "target": "species_10091862" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091860", "target": "reaction_10091864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIN5", "target": "species_10091860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIN5", "target": "species_10091862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020331", "target": "A0A452DIN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXR0", "target": "species_10091860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXR0", "target": "species_10091862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030984", "target": "F1MXR0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFC6", "target": "species_10091860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFC6", "target": "species_10091862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072393", "target": "F1MFC6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091921", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091921", "target": "species_10091827" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091918", "target": "reaction_10091921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090266", "target": "species_10090264" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090262", "target": "reaction_10090266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPX4", "target": "species_10090262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPX4", "target": "species_10090264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082212", "target": "A0A3Q1MPX4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS60", "target": "species_10090262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS60", "target": "species_10090264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012813", "target": "F1MS60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI46", "target": "species_10090262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI46", "target": "species_10090264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032505", "target": "Q2KI46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDU0", "target": "species_10090262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDU0", "target": "species_10090264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018391", "target": "A2VDU0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090239", "target": "reaction_10090266" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090239", "target": "reaction_10090369" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090239", "target": "reaction_10090246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK42", "target": "species_10090239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK42", "target": "species_10090264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK42", "target": "species_10090367" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK42", "target": "species_10090241" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018269", "target": "F1MK42" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090369", "target": "species_10090367" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090246", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090246", "target": "species_10090241" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090243", "target": "reaction_10090246" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092002", "target": "species_10092000" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091998", "target": "reaction_10092002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045869", "target": "species_10091998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045869", "target": "A5PKJ7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092000", "target": "reaction_10092020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ7", "target": "species_10092000" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKJ7", "target": "species_10092018" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092020", "target": "species_10092018" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092016", "target": "reaction_10092020" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063353", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063353", "target": "species_10047760" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047757", "target": "reaction_10063353" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047757", "target": "reaction_10047763" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061497", "target": "species_10047757" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061497", "target": "species_10047760" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047644", "target": "reaction_10063353" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073755", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073755", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073755", "target": "species_3299686" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10073755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10088867" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10076360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10064346" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10076856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10076863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352327", "target": "reaction_10076884" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3299686", "target": "reaction_10067388" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073752", "target": "reaction_10073755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFF3", "target": "species_10073752" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018021", "target": "E1BFF3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091180", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091180", "target": "species_10091162" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091177", "target": "reaction_10091180" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091162", "target": "reaction_10091169" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040565", "target": "reaction_10091180" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091169", "target": "species_10091166" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091164", "target": "reaction_10091169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022592", "target": "species_10091164" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022592", "target": "Q5BIN5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022592", "target": "species_10053086" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091166", "target": "reaction_10091175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10091166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10091173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10053093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10066668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10066666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIN5", "target": "species_10086153" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073731", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073731", "target": "species_2000345" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073731", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073729", "target": "reaction_10073731" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28782", "target": "species_10073729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28782", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28782", "target": "species_10079947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066555", "target": "P28782" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_1629751", "target": "reaction_10073731" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073716", "target": "species_10073714" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091175", "target": "species_10091173" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091175", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070605", "target": "reaction_10091175" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070605", "target": "reaction_10070615" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10070605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10091269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10091273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10091252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10091257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10070655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10070612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSP9", "target": "species_10070626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070692", "target": "A0A3Q1MSP9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063374", "target": "species_10061166" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043441", "target": "reaction_10063374" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043441", "target": "reaction_10043461" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063372", "target": "reaction_10063374" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10061166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084883", "target": "A0A3Q1M5Y2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148J6", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148J6", "target": "species_10061166" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070990", "target": "Q148J6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHR7", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHR7", "target": "species_10061166" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070600", "target": "Q3MHR7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10061166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXC8", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064442", "target": "G3MXC8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMB5", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMB5", "target": "species_10061166" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082840", "target": "A0A3Q1NMB5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CQ2", "target": "species_10063372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CQ2", "target": "species_10061166" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064158", "target": "Q58CQ2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073577", "target": "species_10073575" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073573", "target": "reaction_10073577" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072515", "target": "species_10072513" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072511", "target": "reaction_10072515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072505", "target": "reaction_10072515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072513", "target": "reaction_10073842" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073842", "target": "species_10073840" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055513", "target": "reaction_10073842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH4", "target": "species_10055513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH4", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH4", "target": "species_10055501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH4", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DH4", "target": "species_10055641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025752", "target": "Q08DH4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7H2", "target": "species_10055513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7H2", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7H2", "target": "species_10055501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7H2", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7H2", "target": "species_10055641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023001", "target": "A6H7H2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH8", "target": "species_10055513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH8", "target": "species_10073840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH8", "target": "species_10055511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH8", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH8", "target": "species_10055641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071358", "target": "A0A3Q1MWH8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073806", "target": "species_10073804" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073802", "target": "reaction_10073806" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050472", "target": "reaction_10073806" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073796", "target": "species_10073794" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073792", "target": "reaction_10073796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076885", "target": "species_10073792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076885", "target": "Q2T9P1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073788", "target": "reaction_10073796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029161", "target": "species_10073788" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029161", "target": "G5E5S3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073784", "target": "reaction_10073796" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S3", "target": "species_10073794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9P1", "target": "species_10073794" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073561", "target": "species_10073543" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073541", "target": "reaction_10073561" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073541", "target": "reaction_10073559" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070929", "target": "species_10073541" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070929", "target": "A0A3Q1LLJ2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070929", "target": "species_10068967" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043459", "target": "reaction_10073561" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043459", "target": "reaction_10073507" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073543", "target": "reaction_10073547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLJ2", "target": "species_10073543" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLJ2", "target": "species_10073555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLJ2", "target": "species_10073567" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073503", "target": "species_10073501" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073499", "target": "reaction_10073503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B718", "target": "species_10073499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B718", "target": "species_10073501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B718", "target": "species_10073505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022075", "target": "E1B718" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073501", "target": "reaction_10073507" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073525", "target": "species_10073523" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073521", "target": "reaction_10073525" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068363", "target": "species_10073521" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068363", "target": "A0A3Q1LMM5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073517", "target": "reaction_10073525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6W5", "target": "species_10073517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6W5", "target": "species_10073523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078036", "target": "A0A3Q1M6W5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMM5", "target": "species_10073523" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073493", "target": "species_10073491" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073489", "target": "reaction_10073493" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073557", "target": "species_10073555" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068967", "target": "reaction_10073557" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073553", "target": "reaction_10073557" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016981", "target": "species_10073553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016981", "target": "E1BJP4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073555", "target": "reaction_10073569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJP4", "target": "species_10073555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJP4", "target": "species_10073567" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10073559", "target": "species_10068967" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10073547", "target": "species_10073541" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073547", "target": "species_10073545" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073539", "target": "reaction_10073547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR1", "target": "species_10073539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR1", "target": "species_10073545" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR1", "target": "species_10048947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR1", "target": "species_10048949" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069763", "target": "A0A3Q1MSR1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068939", "target": "species_10068937" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068935", "target": "reaction_10068939" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068931", "target": "reaction_10068939" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068931", "target": "reaction_10069299" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073549", "target": "species_10073537" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073535", "target": "reaction_10073549" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073569", "target": "species_10073567" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073565", "target": "reaction_10073569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072829", "target": "species_10073565" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072829", "target": "A0A3Q1M5I0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5I0", "target": "species_10073567" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073507", "target": "species_10073505" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043461", "target": "species_10043459" }, { "type": "reactant", "sub_type": "", "source": "species_10043457", "target": "reaction_10043461" }, { "type": "reactant", "sub_type": "", "source": "species_10043457", "target": "reaction_10048951" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068933", "target": "species_10068931" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068929", "target": "reaction_10068933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068927", "target": "reaction_10068933" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092203", "target": "species_10092201" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092199", "target": "reaction_10092203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW1", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW1", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW1", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW1", "target": "species_10083333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW1", "target": "species_10083323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014511", "target": "Q08DW1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX32", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX32", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX32", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX32", "target": "species_10083323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015669", "target": "Q3SX32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015669", "target": "species_10083337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCB4", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCB4", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCB4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCB4", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026403", "target": "Q0VCB4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2Y1", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064452", "target": "G3N2Y1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10092199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL53", "target": "species_10056633" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030804", "target": "E1BL53" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083329", "target": "reaction_10092203" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083329", "target": "reaction_10092208" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083329", "target": "reaction_10083342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2K6", "target": "species_10083329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2K6", "target": "species_10092201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2K6", "target": "species_10083335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2K6", "target": "species_10083331" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080085", "target": "A0A3Q1M2K6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080085", "target": "species_10083327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092205", "target": "species_10083329" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083327", "target": "reaction_10092205" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092208", "target": "species_10083335" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092208", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071262", "target": "species_10071260" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044442", "target": "reaction_10071262" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044442", "target": "reaction_10044446" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044442", "target": "reaction_10044726" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071258", "target": "reaction_10071262" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011740", "target": "species_10071258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011740", "target": "A7MB71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB71", "target": "species_10071260" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064931", "target": "reaction_10064933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N727", "target": "species_10064931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060953", "target": "F1N727" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ37", "target": "species_10064931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005438", "target": "E1BJ37" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043311", "target": "species_10043002" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042988", "target": "reaction_10043311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSA1", "target": "species_10042988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSA1", "target": "species_10043002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078787", "target": "A0A3Q1LSA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCE7", "target": "species_10042988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCE7", "target": "species_10043002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000282", "target": "F1MCE7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043000", "target": "reaction_10043311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGJ6", "target": "species_10043000" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGJ6", "target": "species_10043002" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGJ6", "target": "species_10056341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGJ6", "target": "species_10056351" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077971", "target": "A0A3Q1MGJ6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077971", "target": "species_10042992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP90", "target": "species_10043000" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP90", "target": "species_10043002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073964", "target": "A0A3Q1LP90" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084542", "target": "species_10084540" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084532", "target": "reaction_10084542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZL1", "target": "species_10084532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZL1", "target": "species_10084540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019912", "target": "F1MZL1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084538", "target": "reaction_10084542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHR7", "target": "species_10084538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHR7", "target": "species_10084540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024657", "target": "E1BHR7" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042969", "target": "reaction_10042976" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072746", "target": "species_10042969" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056354", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056354", "target": "species_10056351" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056341", "target": "reaction_10056354" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07995", "target": "species_10056341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07995", "target": "species_10056351" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07995", "target": "species_10045724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07995", "target": "species_10045734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07995", "target": "species_10045722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066382", "target": "P07995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSQ2", "target": "species_10056341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSQ2", "target": "species_10056351" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046665", "target": "F1MSQ2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046665", "target": "species_10056339" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056356", "target": "species_10056341" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056339", "target": "reaction_10056356" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042992", "target": "reaction_10056356" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045724", "target": "reaction_10056356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068704", "target": "species_10068702" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060420", "target": "reaction_10068704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080996", "target": "species_10060420" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080996", "target": "F1N7M1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043116", "target": "reaction_10068704" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068702", "target": "reaction_10068707" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7M1", "target": "species_10068702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7M1", "target": "species_10060426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7M1", "target": "species_10060470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7M1", "target": "species_10060576" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068707", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068707", "target": "species_179856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_392417", "target": "reaction_10068707" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_392417", "target": "reaction_10060556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_392417", "target": "reaction_10085310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_392417", "target": "reaction_10085313" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_392417", "target": "reaction_10060569" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067694", "target": "species_10067691" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067672", "target": "reaction_10067694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10067672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10067691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10067668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10067689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10087595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY1", "target": "species_10069649" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079758", "target": "A0A3Q1LJY1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10067672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10067691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10067668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10067689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10087595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE2", "target": "species_10069649" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069289", "target": "A0A3Q1LTE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10067672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10067691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10067668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10067689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10087595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3K5", "target": "species_10069649" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073140", "target": "A0A3Q1M3K5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10067672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10067691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10037287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10037291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10037283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWG5", "target": "species_10091195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067597", "target": "G3MWG5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067597", "target": "species_10067670" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067597", "target": "species_10037281" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067691", "target": "reaction_10067698" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067696", "target": "species_10067672" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067670", "target": "reaction_10067696" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067668", "target": "reaction_10067696" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067668", "target": "reaction_10087597" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067698", "target": "species_10067670" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067698", "target": "species_10067689" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068095", "target": "species_10068071" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068095", "target": "species_10033408" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068083", "target": "reaction_10068095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M230", "target": "species_10068083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M230", "target": "species_10068071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M230", "target": "species_10068069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M230", "target": "species_10068067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M230", "target": "species_10068075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085809", "target": "A0A3Q1M230" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R5", "target": "species_10068083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R5", "target": "species_10068071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R5", "target": "species_10068069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R5", "target": "species_10068067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8R5", "target": "species_10068075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001917", "target": "E1B8R5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T139", "target": "species_10068083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T139", "target": "species_10068071" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038099", "target": "Q3T139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038099", "target": "species_10068054" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068071", "target": "reaction_10068086" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10068092", "target": "reaction_10068095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078346", "target": "species_10068092" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068073", "target": "species_10068071" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068054", "target": "reaction_10068073" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068069", "target": "reaction_10068073" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068088", "target": "species_10068075" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041524", "target": "reaction_10068088" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041524", "target": "reaction_10041583" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068067", "target": "reaction_10068088" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068075", "target": "reaction_10068078" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068078", "target": "species_197277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068078", "target": "species_10068069" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197277", "target": "reaction_10071643" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197277", "target": "reaction_10041824" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068086", "target": "species_10068083" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067879", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067879", "target": "species_10067852" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10067879" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086303" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10048720" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10044381" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10044390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10069937" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072752" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070962" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072725" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072788" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072823" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10069846" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072778" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072813" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10069838" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10072750" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070409" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070377" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10073416" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070392" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070282" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10070516" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10066876" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10081877" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086493" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086509" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086525" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086541" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086502" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086518" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10086534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_77087", "target": "reaction_10074670" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067848", "target": "reaction_10067879" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10067848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10067852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10035231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10035252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10035250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10048700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10048712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10071014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10070273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10035060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10070419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10072800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10072821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10064889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10068658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10067575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10070518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10073414" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10064891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10064897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10064901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10065198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10066768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10066770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10051457" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10091219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62803", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072717", "target": "P62803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10067848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10067852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10035231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10035252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10035250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10048700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10048712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10071014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10070273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10035060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10070419" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10072800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10072821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10064889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10068658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10067575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10070518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10073414" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10064891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10064897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10064901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10065198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10066768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10066770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10051457" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10091219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV7", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085055", "target": "A0A3Q1LMV7" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067876", "target": "reaction_10067879" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHP8", "target": "species_10067876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012057", "target": "F1MHP8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10067876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP4", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001294", "target": "E1BEP4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ99", "target": "species_10067876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ99", "target": "species_10087593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ99", "target": "species_10087595" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068676", "target": "A0A3Q1MZ99" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN6", "target": "species_10067876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN6", "target": "species_10087593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN6", "target": "species_10087595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN6", "target": "species_10071346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN6", "target": "species_10071354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079320", "target": "A0A3Q1MAN6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10067876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUE3", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021204", "target": "A4FUE3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPF3", "target": "species_10067876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080372", "target": "E1BPF3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6V2", "target": "species_10067876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067448", "target": "A0A3Q1M6V2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10067876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7T9", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083957", "target": "A0A3Q1N7T9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071330", "target": "species_10071328" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071326", "target": "reaction_10071330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10071326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10071328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R1", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021312", "target": "F1N5R1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071324", "target": "reaction_10071330" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071795", "target": "species_10071324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071795", "target": "A0A3Q1N0Q2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Q2", "target": "species_10071328" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069645", "target": "species_10069643" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069631", "target": "reaction_10069645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH47", "target": "species_10069631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH47", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH47", "target": "species_10069629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH47", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029170", "target": "F1MH47" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME23", "target": "species_10069631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME23", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME23", "target": "species_10069629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME23", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078037", "target": "F1ME23" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RLD1", "target": "species_10069631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RLD1", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RLD1", "target": "species_10069629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RLD1", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018083", "target": "F6RLD1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK6", "target": "species_10069631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK6", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK6", "target": "species_10069615" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK6", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017631", "target": "A0A452DIK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10069631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10069615" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10069661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10089709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10089711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10043669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10045515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10049021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10089395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10048933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10048947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ7", "target": "species_10048949" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061059", "target": "F1MLJ7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061059", "target": "species_10043667" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069641", "target": "reaction_10069645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCX1", "target": "species_10069641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCX1", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCX1", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083590", "target": "A0A3Q1MCX1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNT4", "target": "species_10069641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNT4", "target": "species_10069643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNT4", "target": "species_10069661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026797", "target": "E1BNT4" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069643", "target": "reaction_10069664" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069647", "target": "species_10069631" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069615", "target": "reaction_10069647" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069629", "target": "reaction_10069647" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069664", "target": "species_10069661" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069607", "target": "species_10069605" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069603", "target": "reaction_10069607" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025871", "target": "species_10069603" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025871", "target": "F1MP88" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043149", "target": "reaction_10069607" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043149", "target": "reaction_10069882" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043149", "target": "reaction_10063568" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP88", "target": "species_10069605" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068923", "target": "species_10068921" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068919", "target": "reaction_10068923" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068917", "target": "reaction_10068923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K7", "target": "species_10068917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K7", "target": "species_10068921" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002946", "target": "F1N4K7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C0", "target": "species_10068917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C0", "target": "species_10068921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C0", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014355", "target": "F1N4C0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069896", "target": "species_10069894" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069892", "target": "reaction_10069896" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC57", "target": "species_10069892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC57", "target": "species_10069894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061589", "target": "E1BC57" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069882", "target": "species_10069878" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069874", "target": "reaction_10069882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ8", "target": "species_10069874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ8", "target": "species_10069878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ8", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLJ8", "target": "species_10085114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061370", "target": "F1MLJ8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061370", "target": "species_10069862" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069876", "target": "species_10069874" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069862", "target": "reaction_10069876" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069299", "target": "species_10069297" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043451", "target": "reaction_10069299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02584", "target": "species_10043451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02584", "target": "species_10069297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024367", "target": "P02584" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024367", "target": "E1BHJ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ0", "target": "species_10043451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ0", "target": "species_10069297" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069448", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069448", "target": "species_10069441" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069448", "target": "species_10037002" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069445", "target": "reaction_10069448" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037002", "target": "reaction_10069456" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037002", "target": "reaction_10037024" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037002", "target": "reaction_10037004" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037002", "target": "reaction_10091075" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069456", "target": "species_10069454" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069452", "target": "reaction_10069456" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069454", "target": "reaction_10069459" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069459", "target": "species_10069445" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069459", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067128", "target": "species_10067126" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067122", "target": "reaction_10067128" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVG1", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068978", "target": "A0A3Q1LVG1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN70", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018592", "target": "F1MN70" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6L8", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002188", "target": "F1N6L8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ82", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083229", "target": "A0A3Q1MQ82" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10067122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10067198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10068835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJR6", "target": "species_10067086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085976", "target": "A0A3Q1MJR6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066990", "target": "reaction_10067128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077814", "target": "species_10066990" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077814", "target": "A0A3Q1MGH5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077814", "target": "species_10067130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077814", "target": "species_10066982" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067126", "target": "reaction_10067202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10067126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10067168" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10066988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10066992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10068795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGH5", "target": "species_10068835" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067200", "target": "species_10067198" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067200", "target": "species_10067130" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067168", "target": "reaction_10067200" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067168", "target": "reaction_10068839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1A0", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086580", "target": "A0A3Q1M1A0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6X8", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018985", "target": "A6H6X8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF5", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081055", "target": "A0A3Q1MPF5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4D7S0", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010650", "target": "A4D7S0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW8", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012148", "target": "F1MEW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK64", "target": "species_10067198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020402", "target": "F1MK64" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067130", "target": "reaction_10067204" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067202", "target": "species_10067168" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066994", "target": "species_10066992" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066988", "target": "reaction_10066994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMH8", "target": "species_10066988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMH8", "target": "species_10066992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025026", "target": "Q1RMH8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD53", "target": "species_10066988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD53", "target": "species_10066992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022455", "target": "Q0VD53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJG5", "target": "species_10066988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJG5", "target": "species_10066992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003239", "target": "Q2HJG5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068837", "target": "species_10068835" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068795", "target": "reaction_10068837" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067124", "target": "species_10067122" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067086", "target": "reaction_10067124" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067204", "target": "species_10066982" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068839", "target": "species_10068795" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041640", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041640", "target": "species_10041594" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041614", "target": "reaction_10041640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMC7", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086393", "target": "A0A3Q1LMC7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086393", "target": "species_10041579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEW4", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057200", "target": "E1BEW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35507", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030064", "target": "P35507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI36", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064284", "target": "A0A3Q1MI36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFM1", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052805", "target": "A0A3Q1NFM1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041581" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041590" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL05", "target": "species_10041599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011639", "target": "E1BL05" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011639", "target": "species_10041570" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041594", "target": "reaction_10041604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041629", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041629", "target": "species_10041614" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041610", "target": "reaction_10041629" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041647", "target": "species_10041634" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041647", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041644", "target": "reaction_10041647" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041634", "target": "reaction_10041637" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041637", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041637", "target": "species_10041610" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063849", "target": "species_10063845" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063841", "target": "reaction_10063849" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10043873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10056243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10071973" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10086712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10086714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10066482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10084098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10084100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10084203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10084211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10040513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10040519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10057814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCF3", "target": "species_10076080" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035306", "target": "Q3ZCF3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035306", "target": "species_10039818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10043873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10072710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10072708" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10086712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10086714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10084098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10084100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10084203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10084211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNF8", "target": "species_10076067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075328", "target": "A0A3Q1LNF8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075328", "target": "species_10043871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10063841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10063845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10043873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10056243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10071973" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10086712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10086714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10066482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10084098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10084100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10084203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10084211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10040513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10040519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10057814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10076089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYD0", "target": "species_10076080" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068449", "target": "F1MYD0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068449", "target": "species_10039822" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087597", "target": "species_10087595" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087593", "target": "reaction_10087597" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071356", "target": "species_10071354" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071346", "target": "reaction_10071356" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071352", "target": "reaction_10071356" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M504", "target": "species_10071352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M504", "target": "species_10071354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066753", "target": "A0A3Q1M504" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069651", "target": "species_10067668" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069649", "target": "reaction_10069651" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041583", "target": "species_10041581" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041570", "target": "reaction_10041583" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041520", "target": "reaction_10041583" }, { "type": "reactant", "sub_type": "", "source": "species_10041566", "target": "reaction_10041583" }, { "type": "catalyst", "sub_type": "", "source": "species_10041566", "target": "reaction_10073930" }, { "type": "catalyst", "sub_type": "", "source": "species_10041566", "target": "reaction_10073942" }, { "type": "catalyst", "sub_type": "", "source": "species_10041566", "target": "reaction_10074231" }, { "type": "reactant", "sub_type": "", "source": "species_10041566", "target": "reaction_10046959" }, { "type": "reactant", "sub_type": "", "source": "species_10041566", "target": "reaction_10049283" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041579", "target": "reaction_10041583" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041581", "target": "reaction_10070931" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070931", "target": "species_10041590" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070931", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063843", "target": "species_10063841" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043873", "target": "reaction_10063843" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043873", "target": "reaction_10072138" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043873", "target": "reaction_10057834" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041599", "target": "reaction_10063843" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041599", "target": "reaction_10041606" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041604", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041604", "target": "species_10041599" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041606", "target": "species_10041599" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060556", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060556", "target": "species_179856" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060426", "target": "reaction_10060556" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060426", "target": "reaction_10060429" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL1", "target": "species_10060426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL1", "target": "species_10060576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076329", "target": "A0A3Q1MBL1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076329", "target": "species_10060424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLC5", "target": "species_10060426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLC5", "target": "species_10060470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLC5", "target": "species_10060576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008015", "target": "A6QLC5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060448", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060448", "target": "species_179856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806240", "target": "reaction_10060448" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060445", "target": "reaction_10060448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR4", "target": "species_10060445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR4", "target": "species_10083089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR4", "target": "species_10060576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR4", "target": "species_10086151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR4", "target": "species_10086153" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024007", "target": "F1MHR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT2", "target": "species_10060445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT2", "target": "species_10083089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT2", "target": "species_10060576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT2", "target": "species_10086151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT2", "target": "species_10086153" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008517", "target": "F1MHT2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087531", "target": "species_10087529" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087525", "target": "reaction_10087531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWB8", "target": "species_10087525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWB8", "target": "species_10087529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWB8", "target": "species_10072652" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079180", "target": "A0A3Q1MWB8" }, { "type": "reactant", "sub_type": "", "source": "species_10087523", "target": "reaction_10087531" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065099", "target": "species_10065097" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043178", "target": "reaction_10065099" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043178", "target": "reaction_10065227" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043178", "target": "reaction_10043182" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10065097" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10037544" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10081899" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10081901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10081903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_5620974" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10091413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10091427" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10043239" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10065892" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6810412", "target": "reaction_10082934" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_8849959" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_8874484" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_8874460" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6810412", "target": "species_10072328" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065227", "target": "species_10036596" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036981", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036981", "target": "species_10036978" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036972", "target": "reaction_10036981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5T5", "target": "species_10036972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5T5", "target": "species_10036978" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086155", "target": "A0A3Q1M5T5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049478", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049478", "target": "species_10049475" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049470", "target": "reaction_10049478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP3", "target": "species_10049470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP3", "target": "species_10049475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP3", "target": "species_10091060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP3", "target": "species_10091064" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009431", "target": "E1BIP3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037022", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037019", "target": "reaction_10037022" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037019", "target": "reaction_10037024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCV4", "target": "species_10037019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066843", "target": "A0A3Q1MCV4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P14100", "target": "species_10037019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P14100", "target": "species_10047944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P14100", "target": "species_10047927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052318", "target": "P14100" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037024", "target": "species_10037019" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037004", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037004", "target": "species_30389" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036997", "target": "reaction_10037004" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036997", "target": "reaction_10039658" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036997", "target": "reaction_10047468" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10036997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA58", "target": "species_10047466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080069", "target": "A0A3Q1MA58" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10036997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9K3", "target": "species_10047466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069484", "target": "E1B9K3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10036997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM79", "target": "species_10047466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073752", "target": "E1BM79" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10041863", "target": "species_10041860" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041863", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041855", "target": "reaction_10041863" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_112275", "target": "reaction_10041863" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_112275", "target": "reaction_10070628" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10070626" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_112275", "target": "reaction_10049182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_112275", "target": "reaction_10043225" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10043223" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10043202" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10043209" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066165" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066057" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066131" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066139" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066170" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10066178" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10072004" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112275", "target": "species_10072019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_112275", "target": "reaction_10072006" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063544", "target": "species_10063542" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063538", "target": "reaction_10063544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10063538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10063542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10063340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10063327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10057278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10057282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10087858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10087860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10088874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10063388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK73", "target": "species_10085759" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "F1MK73" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "species_10057276" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "species_10063312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "species_10057280" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "species_10063290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006112", "target": "species_10088870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEH9", "target": "species_10063538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEH9", "target": "species_10063542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEH9", "target": "species_10063552" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069935", "target": "A0A3Q1MEH9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069935", "target": "species_10063536" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063550", "target": "species_10063548" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063550" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063346" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063380" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063338" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063534" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063333", "target": "reaction_10063554" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084991", "target": "species_10063333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084991", "target": "A0A3Q1NBB6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084991", "target": "species_10063336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084991", "target": "species_10063378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063546", "target": "reaction_10063550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038824", "target": "species_10063546" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038824", "target": "F1N2D3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D3", "target": "species_10063548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D3", "target": "species_10040945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D3", "target": "species_10040952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D3", "target": "species_10040959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBB6", "target": "species_10063548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBB6", "target": "species_10063566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBB6", "target": "species_10063344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBB6", "target": "species_10063552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBB6", "target": "species_10063398" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063408", "target": "species_10063406" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063404", "target": "reaction_10063408" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019472", "target": "species_10063404" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019472", "target": "F1N3I6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063259", "target": "reaction_10063408" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063259", "target": "reaction_10063319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9F9", "target": "species_10063259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9F9", "target": "species_10063406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9F9", "target": "species_10063275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9F9", "target": "species_10063292" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019161", "target": "E1B9F9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCH5", "target": "species_10063259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCH5", "target": "species_10063406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCH5", "target": "species_10063314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCH5", "target": "species_10063275" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020062", "target": "E1BCH5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3I6", "target": "species_10063406" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063568", "target": "species_10063566" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063336", "target": "reaction_10063568" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063346", "target": "species_10063344" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063303", "target": "reaction_10063346" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063303", "target": "reaction_10063305" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063303", "target": "reaction_10063338" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063303", "target": "reaction_10063342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X1", "target": "species_10063303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X1", "target": "species_10063344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X1", "target": "species_10063340" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077481", "target": "A0A3Q1M4X1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV8", "target": "species_10063303" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV8", "target": "species_10063344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV8", "target": "species_10063340" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025212", "target": "A0A452DIV8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063317", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063317", "target": "species_10063312" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10063317" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10063382" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10063305" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10063342" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10063556" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057276", "target": "reaction_10057286" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063314", "target": "reaction_10063317" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063314", "target": "reaction_10063534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W1", "target": "species_10063314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W1", "target": "species_10063273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W1", "target": "species_10063275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W1", "target": "species_10063292" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081411", "target": "A0A3Q1M4W1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBK1", "target": "species_10063314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBK1", "target": "species_10063273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBK1", "target": "species_10063275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBK1", "target": "species_10063292" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081480", "target": "A0A3Q1MBK1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063380", "target": "species_10063378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063378", "target": "reaction_10063400" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063319", "target": "species_10063275" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063273", "target": "reaction_10063319" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063382", "target": "species_10057280" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057280", "target": "reaction_10088872" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057280", "target": "reaction_10063390" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057280", "target": "reaction_10085761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063305", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063305", "target": "species_10063290" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063290", "target": "reaction_10063329" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063292", "target": "reaction_10063305" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063292", "target": "reaction_10063338" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063338", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063338", "target": "species_10063336" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063342", "target": "species_10063340" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063534", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063534", "target": "species_10063336" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063329", "target": "species_10063327" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037668", "target": "reaction_10063329" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037668", "target": "reaction_10073917" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037668", "target": "reaction_10073921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10037668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10063327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073896" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074213" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10090951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10090933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10090946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10047517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10047515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10037670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10037672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10072612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10091019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10091021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10051064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T894", "target": "species_10050316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022411", "target": "A0A140T894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022411", "target": "species_10037666" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063554", "target": "species_10063552" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063536", "target": "reaction_10063554" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063536", "target": "reaction_10063556" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063556", "target": "species_10063538" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043753", "target": "species_10043750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043753", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043753", "target": "species_10043747" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037714", "target": "reaction_10043753" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078264", "target": "species_10037714" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078264", "target": "species_10043750" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078264", "target": "A0A3Q1NJ55" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078264", "target": "species_10037721" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078264", "target": "species_10037725" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037676", "target": "reaction_10043753" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037676", "target": "reaction_10037678" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016610", "target": "species_10037676" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016610", "target": "species_10043747" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016610", "target": "species_10037644" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016610", "target": "F1MUT9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016610", "target": "species_10037626" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10041333", "target": "species_10039497" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039497", "target": "reaction_10074747" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043739", "target": "species_10043737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043729", "target": "reaction_10043739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10043729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10043737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10043741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A8", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083119", "target": "A0A3Q1M6A8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083119", "target": "species_10043727" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043744", "target": "species_10043729" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043741", "target": "reaction_10043744" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043723", "target": "reaction_10043744" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043778", "target": "species_10043741" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043719", "target": "reaction_10043778" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043727", "target": "reaction_10043778" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043761", "target": "reaction_10043778" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043877", "target": "species_10043875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8WNW7", "target": "species_10043875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8WNW7", "target": "species_10077358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8WNW7", "target": "species_10077360" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041470", "target": "species_10037315" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041467", "target": "reaction_10041470" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071524", "target": "species_10071521" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071516", "target": "reaction_10071524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10071516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10071521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10071514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10077337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10073696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW8", "target": "species_10074251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034719", "target": "Q3SYW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10071516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10071521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10071514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10077337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10073696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT71", "target": "species_10074251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070103", "target": "A0A3Q1MT71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10071516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10071521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10036142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10036144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10037952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10071532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10075944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10075949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10075986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10067330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10072344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10070680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10091777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10070686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10091781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10067320" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10072328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10072338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10067318" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10070524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10070526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10070529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10037987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK6", "target": "species_10037989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008367", "target": "Q3SZK6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008367", "target": "species_10071528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10071516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10071521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10036142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10036144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10037952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10071532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10037987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI74", "target": "species_10037989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016776", "target": "Q2KI74" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10071516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10071521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10036142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10036144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10037952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10071532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10073696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10037987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D9", "target": "species_10037989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013869", "target": "E1B9D9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071521", "target": "reaction_10071556" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071521", "target": "reaction_10071541" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071556", "target": "species_10071554" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071552", "target": "reaction_10071556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMK3", "target": "species_10071552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMK3", "target": "species_10071554" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061147", "target": "E1BMK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10071552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10071554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPC8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022612", "target": "Q1JPC8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDF2", "target": "species_10071552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDF2", "target": "species_10071554" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049670", "target": "E1BDF2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071526", "target": "species_10071516" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036142", "target": "reaction_10071526" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071514", "target": "reaction_10071526" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071514", "target": "reaction_10077339" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071514", "target": "reaction_10074254" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037964", "target": "species_10037952" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035378", "target": "reaction_10037964" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035378", "target": "reaction_10036148" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024322", "target": "species_10035378" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024322", "target": "Q645M6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036144", "target": "reaction_10037964" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037952", "target": "reaction_10071534" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037952", "target": "reaction_10067895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10037952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10071532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10035380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10035386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10068044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10037981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10067889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10037983" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10035390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10037987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q645M6", "target": "species_10037989" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037962", "target": "reaction_10037964" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037962", "target": "reaction_10071541" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10037962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10085342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKI9", "target": "species_10075986" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069028", "target": "A0A3Q1NKI9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069028", "target": "species_10037956" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067908", "target": "species_10067885" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067908", "target": "species_10067899" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036154", "target": "reaction_10067908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ61", "target": "species_10036154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ61", "target": "species_10067885" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ61", "target": "species_10067899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035815", "target": "A0A452DJ61" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035815", "target": "species_10084710" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035815", "target": "species_10084708" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067899", "target": "reaction_10084723" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067905", "target": "reaction_10067908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B867", "target": "species_10067905" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001519", "target": "E1B867" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092026", "target": "species_10092024" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092026", "target": "species_10068040" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067893", "target": "reaction_10092026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10067893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10092024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10092028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10068044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX3", "target": "species_10067889" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085853", "target": "A0A3Q1MLX3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085853", "target": "species_10068040" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085853", "target": "species_10067887" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085853", "target": "species_10035394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085853", "target": "species_10068034" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092024", "target": "reaction_10092031" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092031", "target": "species_10092028" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092031", "target": "species_10071528" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071534", "target": "species_10071532" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071534", "target": "species_10071528" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084723", "target": "species_10084710" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084723", "target": "species_10084708" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084720", "target": "reaction_10084723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBP7", "target": "species_10084720" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077127", "target": "A0A3Q1MBP7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKF8", "target": "species_10084720" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035792", "target": "E1BKF8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071541", "target": "species_10033408" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071541", "target": "species_10071516" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071539", "target": "reaction_10071541" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026221", "target": "species_10071539" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067895", "target": "species_10067893" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067887", "target": "reaction_10067895" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067887", "target": "reaction_10068046" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067887", "target": "reaction_10067891" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035384", "target": "reaction_10067895" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035384", "target": "reaction_10036146" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035384", "target": "reaction_10037985" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035384", "target": "reaction_10035396" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035384", "target": "reaction_10037991" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035726", "target": "species_10033922" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033920", "target": "reaction_10035726" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014282", "target": "species_10033920" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014282", "target": "A5D7R0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033916", "target": "reaction_10035726" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046575", "target": "species_10033916" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046575", "target": "A6H6Z6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033922", "target": "reaction_10033926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10033922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10035380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10035386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10033924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10068044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Z6", "target": "species_10035390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10033922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10035380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10035386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10033924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10068026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10068028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10068032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10068038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10068044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R0", "target": "species_10035390" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036146", "target": "species_10035386" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035380", "target": "reaction_10036146" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035386", "target": "reaction_10068046" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035386", "target": "reaction_10035396" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036148", "target": "species_10035380" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033924", "target": "reaction_10036148" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033926", "target": "species_10033924" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045016", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045016", "target": "species_10045005" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045007", "target": "reaction_10045016" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045007", "target": "reaction_10053213" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10045007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10045005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61223", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019575", "target": "P61223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10045007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10045005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10049502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10049504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10090951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10090933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10090946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10039587" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10039589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10046644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62833", "target": "species_10046646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068678", "target": "P62833" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045005", "target": "reaction_10047519" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045013", "target": "reaction_10045016" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10045013" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10048630" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10048541" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10037546" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_10056236" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6797635", "target": "species_5696066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG59", "target": "species_10045013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG59", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG59", "target": "species_10056236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029159", "target": "E1BG59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053213", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053213", "target": "species_10045005" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047532", "target": "reaction_10053213" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047532", "target": "reaction_10047536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPX7", "target": "species_10047532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPX7", "target": "species_10047534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPX7", "target": "species_10044626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061074", "target": "E1BPX7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061074", "target": "species_10044624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHN3", "target": "species_10047532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHN3", "target": "species_10047534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHN3", "target": "species_10044632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085533", "target": "A0A3Q1LHN3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085533", "target": "species_10044630" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049279", "target": "species_10049276" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037443", "target": "reaction_10049279" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049506", "target": "species_10049504" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049502", "target": "reaction_10049506" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071673", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071673", "target": "species_975622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071673", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975599", "target": "reaction_10071673" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975599", "target": "reaction_10071648" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975622", "target": "reaction_10071691" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975622", "target": "reaction_10071659" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975622", "target": "reaction_10072225" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975622", "target": "species_10054390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975622", "target": "reaction_10065437" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071670", "target": "reaction_10071673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFZ4", "target": "species_10071670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFZ4", "target": "species_10034203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003769", "target": "F1MFZ4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076840", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076840", "target": "species_5362520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076840", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5362565", "target": "reaction_10076840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5362520", "target": "reaction_10044211" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5362520", "target": "species_5246487" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5362520", "target": "species_10070969" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076837", "target": "reaction_10076840" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010485", "target": "species_10076837" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071691", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071691", "target": "species_975599" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071688", "target": "reaction_10071691" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZD5", "target": "species_10071688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023493", "target": "F1MZD5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM93", "target": "species_10071688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM93", "target": "species_10071675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM93", "target": "species_10035576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002535", "target": "E1BM93" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002535", "target": "species_10035574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QW3", "target": "species_10071688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006933", "target": "Q17QW3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071659", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071659", "target": "species_5334816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071659", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5334816", "target": "reaction_10072397" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5334816", "target": "reaction_10071397" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071656", "target": "reaction_10071659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48644", "target": "species_10071656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48644", "target": "species_10034172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010661", "target": "P48644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHR3", "target": "species_10071656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012030", "target": "F1MHR3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072397", "target": "species_10071666" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071664", "target": "reaction_10072397" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017158", "target": "species_10071664" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017158", "target": "P62964" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071666", "target": "reaction_10071668" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10071666" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10071403" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10071405" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10071395" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10072626" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_5246487" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_215573", "target": "species_10070969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_215573", "target": "reaction_10044158" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_215573", "target": "reaction_10044293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62964", "target": "species_10071666" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071678", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071678", "target": "species_32737" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071678", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30927", "target": "reaction_10071678" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30927", "target": "reaction_10065644" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_32737", "target": "species_10035566" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_32737", "target": "reaction_10065606" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_32737", "target": "reaction_10091560" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_32737", "target": "reaction_10065675" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_32737", "target": "reaction_10091558" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071675", "target": "reaction_10071678" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27979", "target": "species_10071675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27979", "target": "species_10065594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065932", "target": "Q27979" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072433", "target": "species_5623650" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072433", "target": "species_5623649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5623644", "target": "reaction_10072433" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5623648", "target": "reaction_10072433" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163953", "target": "reaction_10072433" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163953", "target": "reaction_10039604" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163953", "target": "reaction_10068716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163953", "target": "reaction_10039047" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072430", "target": "reaction_10072433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029403", "target": "species_10072430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072225", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072225", "target": "species_975599" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071648", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071648", "target": "species_975622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071648", "target": "species_73473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071645", "target": "reaction_10071648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HYR6", "target": "species_10071645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005986", "target": "Q8HYR6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0V8D0", "target": "species_10071645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001829", "target": "Q0V8D0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZT6", "target": "species_10071645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZT6", "target": "species_10035576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026830", "target": "Q8HZT6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044211", "target": "species_5362524" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044211", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044211", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044208", "target": "reaction_10044211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056396", "target": "species_10044208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056396", "target": "E1BDT5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071668", "target": "species_29356" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071668", "target": "species_10071664" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071668", "target": "species_5362521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071668", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044290", "target": "reaction_10071668" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044290", "target": "reaction_10044293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZS4", "target": "species_10044290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028140", "target": "F1MZS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ4", "target": "species_10044290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016198", "target": "E1BHJ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDT5", "target": "species_10044290" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071407", "target": "species_10071405" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071399", "target": "reaction_10071407" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X1", "target": "species_10071399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X1", "target": "species_10071405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X1", "target": "species_10072626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X1", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X1", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015305", "target": "G3X6X1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10071399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10071405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10072626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10090569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7I6", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000860", "target": "A6H7I6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071403", "target": "reaction_10071407" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX32", "target": "species_10071403" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX32", "target": "species_10071405" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX32", "target": "species_10071395" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087158", "target": "A0A3Q1LX32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087158", "target": "species_10071393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087158", "target": "species_10071401" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071405", "target": "reaction_10072628" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071397", "target": "species_10071395" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071393", "target": "reaction_10071397" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071395", "target": "reaction_10072630" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072628", "target": "species_10072626" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072628", "target": "species_10071401" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072630", "target": "species_10071403" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090456", "target": "species_10090454" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090456", "target": "species_10090444" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090450", "target": "reaction_10090456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10090569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B6", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071739", "target": "Q5E9B6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071739", "target": "species_10045642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPA7", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPA7", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPA7", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPA7", "target": "species_10068722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013888", "target": "F1MPA7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10068722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10044704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10044724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B7TCI5", "target": "species_10047805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084466", "target": "B7TCI5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10068722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10044704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10044724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ9", "target": "species_10047805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087441", "target": "A0A3Q1MSZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10068722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10044722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10044724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0W0", "target": "species_10047771" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023086", "target": "F1N0W0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10090551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10044694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10068722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10044724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10047771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGM4", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061343", "target": "F1MGM4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10090444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10090448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10090551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10044694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10068722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10044724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10047771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY21", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086068", "target": "A0A3Q1MY21" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_9024383" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192060", "target": "species_10090569" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192060", "target": "reaction_10041217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_9024383" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:67237", "target": "species_10090569" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_9024383" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090569" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024328", "target": "reaction_10090712" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024328", "target": "species_10090710" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090450" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_9024383" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090553" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090565" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:41633", "target": "species_10090569" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090454", "target": "reaction_10090559" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090559", "target": "species_10090557" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047785", "target": "reaction_10090559" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047785", "target": "reaction_10090571" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064008", "target": "species_10047785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064008", "target": "G3N0C2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064008", "target": "species_10071878" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090557", "target": "reaction_10090563" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10090557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10090561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10090569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10071884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C2", "target": "species_10047805" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090563", "target": "species_10090561" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10090563" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10089761" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10068569" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10087889" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10088490" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10083072" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10066724" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053052", "target": "reaction_10084895" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090452", "target": "species_10090450" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090448", "target": "reaction_10090452" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9024383", "target": "reaction_10090452" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9024383", "target": "reaction_10090555" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090555", "target": "species_10090553" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090551", "target": "reaction_10090555" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090553", "target": "reaction_10090567" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090571", "target": "species_10090569" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090565", "target": "reaction_10090571" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090567", "target": "species_10044694" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090567", "target": "species_10090565" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044694", "target": "reaction_10044726" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044694", "target": "reaction_10046681" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090712", "target": "species_10090710" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045570", "target": "reaction_10090712" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005899", "target": "species_10045570" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005899", "target": "Q9XSB5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10090710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10086682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10086684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10086658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10086660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSB5", "target": "species_10046679" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092314", "target": "species_10086684" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086682", "target": "reaction_10092314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26882", "target": "species_10086682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P26882", "target": "species_10086684" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022180", "target": "P26882" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1254400", "target": "reaction_10092314" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1254400", "target": "species_10086684" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1254400", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1254400", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1254400", "target": "species_10086658" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1254400", "target": "species_10086660" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089761", "target": "species_10089759" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089757", "target": "reaction_10089761" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ27", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ27", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ27", "target": "species_10077308" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ27", "target": "species_10077314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ27", "target": "species_10084933" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076263", "target": "Q2HJ27" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076263", "target": "species_10077310" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4J1", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4J1", "target": "species_10089759" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056983", "target": "F2Z4J1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10089757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10089759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10035231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10035252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10035250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10048700" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10048712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10071014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10066768" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10066770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10055866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F8", "target": "species_10055868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034695", "target": "Q5E9F8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034695", "target": "species_10035227" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091115", "target": "species_10091108" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091115", "target": "species_10040221" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091106", "target": "reaction_10091115" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040221", "target": "reaction_10064910" }, { "type": "catalyst", "sub_type": "", "source": "species_10091110", "target": "reaction_10091115" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091113", "target": "reaction_10091115" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR17", "target": "species_10091113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR17", "target": "species_10046319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR17", "target": "species_10046321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR17", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR17", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015111", "target": "A6QR17" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015111", "target": "species_10046309" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419305", "target": "species_10091113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419305", "target": "reaction_10048180" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419305", "target": "species_10046321" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419305", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419305", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419305", "target": "reaction_10048995" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091275", "target": "species_10091273" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091269", "target": "reaction_10091275" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091260", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091260", "target": "species_10091257" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091252", "target": "reaction_10091260" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091257", "target": "reaction_10091271" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091271", "target": "species_10091269" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091151", "target": "species_10091149" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10091151" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10040460" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10040453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10040258" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10040326" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040243", "target": "reaction_10044465" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043033", "target": "reaction_10091151" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043033", "target": "reaction_10043039" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085237", "target": "species_10043033" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085237", "target": "A0A3Q1N508" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085237", "target": "species_10043037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085237", "target": "species_10043035" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091149", "target": "reaction_10091156" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10091149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10091153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10070580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10070586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10070591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10070578" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10047453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N508", "target": "species_10069139" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091156", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091156", "target": "species_10091153" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091118", "target": "species_10091011" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042685", "target": "reaction_10091118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10042685" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10091011" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10075234" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10075226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10075232" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10091084" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "species_10042665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014920", "target": "F1N4K5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091011", "target": "reaction_10091029" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091267", "target": "species_10091265" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091263", "target": "reaction_10091267" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "species_10091263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "species_10091265" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "A6QLS3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "species_10040499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "species_10083560" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024297", "target": "species_10040501" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050265", "target": "reaction_10091267" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050265", "target": "reaction_10075253" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050265", "target": "reaction_10092271" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050265", "target": "reaction_10050306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017629", "target": "species_10050265" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017629", "target": "E1BE98" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091158", "target": "species_10091113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5218688", "target": "reaction_10091158" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046309", "target": "reaction_10091158" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086662", "target": "species_10086660" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086658", "target": "reaction_10086662" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086575", "target": "species_10086573" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048262", "target": "reaction_10086575" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048262", "target": "reaction_10048270" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081022", "target": "species_10048262" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081022", "target": "A0A3Q1N5S8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086571", "target": "reaction_10086575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKP4", "target": "species_10086571" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKP4", "target": "species_10086573" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025398", "target": "F1MKP4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95MI6", "target": "species_10086571" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95MI6", "target": "species_10086573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95MI6", "target": "species_10048268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95MI6", "target": "species_10086563" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047063", "target": "Q95MI6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047063", "target": "species_10048266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S8", "target": "species_10086573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S8", "target": "species_10048268" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048270", "target": "species_10048268" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048266", "target": "reaction_10048270" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048266", "target": "reaction_10086565" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049681", "target": "species_10049679" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049677", "target": "reaction_10049681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8L4", "target": "species_10049677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8L4", "target": "species_10049679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082095", "target": "A0A3Q1M8L4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0R0", "target": "species_10049677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0R0", "target": "species_10049679" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0R0", "target": "species_10051905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0R0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0R0", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081916", "target": "A0A3Q1M0R0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081916", "target": "species_10049671" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051907", "target": "species_10051905" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049671", "target": "reaction_10051907" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051903", "target": "reaction_10051907" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078403", "target": "species_10051903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078403", "target": "A0A3Q1LQX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQX2", "target": "species_10051905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQX2", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQX2", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQX2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQX2", "target": "species_10079197" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086565", "target": "species_10086563" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086561", "target": "reaction_10086565" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026905", "target": "species_10086561" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026905", "target": "A7MBA3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA3", "target": "species_10086563" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048248", "target": "species_10048246" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048244", "target": "reaction_10048248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10048244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "P01272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10038908" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10048376" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10048378" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10046709" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000972", "target": "species_10046626" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048242", "target": "reaction_10048248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006662", "target": "species_10048242" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006662", "target": "E1BAY1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAY1", "target": "species_10048246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01272", "target": "species_10048246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01272", "target": "species_10038916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01272", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01272", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048282", "target": "species_10048280" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048278", "target": "reaction_10048282" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071185", "target": "species_10048278" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071185", "target": "A0A3Q1M5G0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048274", "target": "reaction_10048282" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079270", "target": "species_10048274" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079270", "target": "A0A3Q1MB83" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB83", "target": "species_10048280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G0", "target": "species_10048280" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048304", "target": "species_10048302" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048290", "target": "reaction_10048304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017827", "target": "species_10048290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017827", "target": "P81401" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048300", "target": "reaction_10048304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIT6", "target": "species_10048300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIT6", "target": "species_10048302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047461", "target": "F1MIT6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF07", "target": "species_10048300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF07", "target": "species_10048302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008625", "target": "F1MF07" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81401", "target": "species_10048302" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038918", "target": "species_10038916" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038912", "target": "reaction_10038918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023275", "target": "species_10038912" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023275", "target": "A7MBH4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023275", "target": "species_10038914" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038908", "target": "reaction_10038918" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10038908", "target": "reaction_10048429" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH4", "target": "species_10038916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH4", "target": "species_10045866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH4", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH4", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH4", "target": "species_10046146" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048326", "target": "species_10048324" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048322", "target": "reaction_10048326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P58073", "target": "species_10048322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P58073", "target": "species_10048324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043154", "target": "P58073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9U9", "target": "species_10048322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9U9", "target": "species_10048324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001408", "target": "E1B9U9" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048312", "target": "reaction_10048326" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061196", "target": "species_10048312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061196", "target": "E1B7Q8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7Q8", "target": "species_10048324" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091763", "target": "species_10091761" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045862", "target": "reaction_10091763" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045862", "target": "reaction_10091812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034352", "target": "species_10045862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034352", "target": "A5PKG3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9684615", "target": "reaction_10091763" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10091761", "target": "reaction_10091812" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG3", "target": "species_10091761" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG3", "target": "species_10045864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG3", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG3", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG3", "target": "species_10046146" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047378", "target": "species_10046259" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045892", "target": "reaction_10047378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045892", "target": "reaction_10047989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008214", "target": "species_10045892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008214", "target": "A2VEA2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_416372", "target": "reaction_10047378" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_416372", "target": "reaction_10091812" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_416372", "target": "reaction_10047398" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_416372" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10046259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10045864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10045866" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15650", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10046259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10045894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA2", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047396", "target": "species_10045936" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045934", "target": "reaction_10047396" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T181", "target": "species_10045934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T181", "target": "species_10045936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T181", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T181", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036478", "target": "Q3T181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRY8", "target": "species_10045934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRY8", "target": "species_10045936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRY8", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRY8", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054992", "target": "F1MRY8" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_416436", "target": "reaction_10047396" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416436", "target": "species_10045936" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416436", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416436", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091812", "target": "species_10045864" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047398", "target": "species_10045866" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038914", "target": "reaction_10047398" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047374", "target": "species_10047372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_416911", "target": "reaction_10047374" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_10047372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_416911", "target": "reaction_10047366" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_10046265" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_879566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416911", "target": "species_879614" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047370", "target": "reaction_10047374" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008808", "target": "species_10047370" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008808", "target": "A0A452DI56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI56", "target": "species_10047372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047376", "target": "species_10045992" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_391930", "target": "reaction_10047376" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10045992" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_391930", "target": "reaction_10047394" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10047392" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_879566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_879614" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10051868" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391930", "target": "species_10051872" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045990", "target": "reaction_10047376" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046806", "target": "species_10045990" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046806", "target": "F1MUY4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY4", "target": "species_10045992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY4", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY4", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047394", "target": "species_10047392" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047390", "target": "reaction_10047394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2L8", "target": "species_10047390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2L8", "target": "species_10047392" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002800", "target": "F1N2L8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ8", "target": "species_10047390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZJ8", "target": "species_10047392" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019930", "target": "F1MZJ8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047380", "target": "species_10045858" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_391932", "target": "reaction_10047380" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10045858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10051660" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10049028" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10049032" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_391932", "target": "reaction_10091701" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_391932", "target": "species_10049011" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045856", "target": "reaction_10047380" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045856", "target": "reaction_10091701" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019892", "target": "species_10045856" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019892", "target": "Q95125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10045858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10051664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10051660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10049028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10049032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10091699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95125", "target": "species_10049011" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047366", "target": "species_10046265" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046263", "target": "reaction_10047366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066986", "target": "species_10046263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066986", "target": "A0A3Q1N2W9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W9", "target": "species_10046265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W9", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047364", "target": "species_10046301" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_416428", "target": "reaction_10047364" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416428", "target": "species_10046301" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416428", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_416428", "target": "species_10046513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046299", "target": "reaction_10047364" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005326", "target": "species_10046299" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005326", "target": "F1MCJ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCJ0", "target": "species_10046301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCJ0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCJ0", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049657", "target": "species_10049655" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444840", "target": "reaction_10049657" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5357505", "target": "species_444840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5357505", "target": "species_10049655" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5357505", "target": "reaction_10085806" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5357505", "target": "species_10085804" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193451", "target": "species_444840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193451", "target": "species_10049655" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193451", "target": "species_194096" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193451", "target": "species_192483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_193451", "target": "species_10041430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_176655", "target": "species_444840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_176655", "target": "species_10049655" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176655", "target": "reaction_10040120" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176655", "target": "reaction_10085806" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_176655", "target": "species_10085804" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16755", "target": "species_444840" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16755", "target": "species_10049655" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16755", "target": "species_194096" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16755", "target": "species_192483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16755", "target": "species_10041430" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049653", "target": "reaction_10049657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005120", "target": "species_10049653" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005120", "target": "Q862A9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862A9", "target": "species_10049655" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047354", "target": "species_10047352" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047350", "target": "reaction_10047354" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01223", "target": "species_10047350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01223", "target": "species_10047352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01223", "target": "species_10043954" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008264", "target": "P01223" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008264", "target": "species_10043952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD70", "target": "species_10047350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD70", "target": "species_10047352" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009286", "target": "E1BD70" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0F7RPV8", "target": "species_10047350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0F7RPV8", "target": "species_10047352" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075524", "target": "A0A0F7RPV8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047338", "target": "reaction_10047354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052615", "target": "species_10047338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052615", "target": "F1N4F6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4F6", "target": "species_10047352" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047362", "target": "species_10047360" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047358", "target": "reaction_10047362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022047", "target": "species_10047358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022047", "target": "A0A140T893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T893", "target": "species_10047360" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047334", "target": "species_10045800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045798", "target": "reaction_10047334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VBW7", "target": "species_10045798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VBW7", "target": "species_10045800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VBW7", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VBW7", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000188", "target": "Q0VBW7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J7", "target": "species_10045798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J7", "target": "species_10045800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J7", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7J7", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069568", "target": "A0A3Q1M7J7" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045788", "target": "reaction_10047334" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000559", "target": "species_10045788" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000559", "target": "P32236" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32236", "target": "species_10045800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32236", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32236", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049659", "target": "species_10046461" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_3296262", "target": "reaction_10049659" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:20067", "target": "species_3296262" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:20067", "target": "species_10046461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:20067", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:20067", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_3296262" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_10046461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_3296330" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_10046465" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197230", "target": "reaction_10041808" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_429748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197230", "target": "species_8876304" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046459", "target": "reaction_10049659" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065393", "target": "species_10046459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065393", "target": "G3N168" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065393", "target": "species_10046463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N168", "target": "species_10046461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N168", "target": "species_10046465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N168", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N168", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048208", "target": "species_10048206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419777", "target": "reaction_10048208" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10048206" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419777", "target": "reaction_10048214" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10045852" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419777", "target": "species_10046142" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419777", "target": "reaction_10035406" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419777", "target": "reaction_10065664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048204", "target": "reaction_10048208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10048204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10048206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10065654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10065662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI7", "target": "species_10065685" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027054", "target": "Q9BGI7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027054", "target": "species_10048186" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027054", "target": "species_10065649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10048204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10048206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10072421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10072423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10072324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10035617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02699", "target": "species_10065942" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "P02699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "species_10035401" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "species_10035404" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "species_2565923" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "species_5623403" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001730", "target": "species_10035601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10048204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10048206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10065654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10065662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51490", "target": "species_10065685" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021912", "target": "P51490" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021912", "target": "species_10048190" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021912", "target": "species_10065652" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048206", "target": "reaction_10048370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048214", "target": "species_10045852" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045850", "target": "reaction_10048214" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040059", "target": "species_10045850" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040059", "target": "E1BEK2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK2", "target": "species_10045852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK2", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045180", "target": "species_10045178" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045172", "target": "reaction_10045180" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013116", "target": "species_10045172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013116", "target": "E1BH62" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045176", "target": "reaction_10045180" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026663", "target": "species_10045176" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026663", "target": "F1N2D2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D2", "target": "species_10045178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D2", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH62", "target": "species_10045178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH62", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH62", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067358", "target": "species_10067356" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049514", "target": "reaction_10067358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016850", "target": "species_10049514" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016850", "target": "Q3ZBN3" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067354", "target": "reaction_10067358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008096", "target": "species_10067354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008096", "target": "Q0II78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II78", "target": "species_10067356" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBN3", "target": "species_10067356" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBN3", "target": "species_10049516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBN3", "target": "species_10049518" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045168", "target": "species_10045166" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045164", "target": "reaction_10045168" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028430", "target": "species_10045164" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028430", "target": "Q8SQB1" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045160", "target": "reaction_10045168" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045160", "target": "reaction_10058492" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037034", "target": "species_10045160" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037034", "target": "F1MT56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT56", "target": "species_10045166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT56", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT56", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT56", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQB1", "target": "species_10045166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQB1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQB1", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045072", "target": "species_10045070" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045054", "target": "reaction_10045072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082438", "target": "species_10045054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082438", "target": "O97919" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045068", "target": "reaction_10045072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ17", "target": "species_10045068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ17", "target": "species_10045070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ17", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ17", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010652", "target": "Q2HJ17" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP16", "target": "species_10045068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP16", "target": "species_10045070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP16", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP16", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001762", "target": "F1MP16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLA5", "target": "species_10045068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLA5", "target": "species_10045070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLA5", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLA5", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049352", "target": "A6QLA5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97919", "target": "species_10045070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97919", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97919", "target": "species_10049568" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97919", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97919", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049520", "target": "species_10049518" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049510", "target": "reaction_10049520" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026082", "target": "species_10049510" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026082", "target": "P35350" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049516", "target": "reaction_10049520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ0", "target": "species_10049516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ0", "target": "species_10049518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ0", "target": "species_10045104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ0", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007331", "target": "Q1RMQ0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007331", "target": "species_10045098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35350", "target": "species_10049518" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045106", "target": "species_10045104" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045102", "target": "reaction_10045106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078248", "target": "species_10045102" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078248", "target": "A4IF92" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045098", "target": "reaction_10045106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF92", "target": "species_10045104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF92", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF92", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045268", "target": "species_10045266" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045264", "target": "reaction_10045268" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077980", "target": "species_10045264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077980", "target": "A0A3Q1M085" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045260", "target": "reaction_10045268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10045260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10045266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10089393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25930", "target": "species_10089395" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001406", "target": "P25930" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF77", "target": "species_10045260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF77", "target": "species_10045266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF77", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF77", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024512", "target": "A4IF77" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M085", "target": "species_10045266" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M085", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M085", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M085", "target": "species_10089393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M085", "target": "species_10089395" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083880", "target": "species_10046471" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046469", "target": "reaction_10083880" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047653", "target": "species_10046469" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047653", "target": "E1BAG6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045080", "target": "reaction_10083880" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020577", "target": "species_10045080" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020577", "target": "F6RDR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RDR3", "target": "species_10046471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RDR3", "target": "species_10045086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RDR3", "target": "species_10045092" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RDR3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RDR3", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAG6", "target": "species_10046471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAG6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAG6", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045196", "target": "species_10045194" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045188", "target": "reaction_10045196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020855", "target": "species_10045188" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020855", "target": "Q5EA94" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045192", "target": "reaction_10045196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024371", "target": "species_10045192" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024371", "target": "Q29RT9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RT9", "target": "species_10045194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RT9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RT9", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA94", "target": "species_10045194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA94", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA94", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045280", "target": "species_10045278" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045276", "target": "reaction_10045280" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019690", "target": "species_10045276" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019690", "target": "Q5MD61" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045272", "target": "reaction_10045280" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075648", "target": "species_10045272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075648", "target": "A9QWP9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A9QWP9", "target": "species_10045278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A9QWP9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A9QWP9", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5MD61", "target": "species_10045278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5MD61", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5MD61", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049570", "target": "species_10049568" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049524", "target": "reaction_10049570" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068509", "target": "species_10049524" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068509", "target": "A0A3Q1LTZ4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049566", "target": "reaction_10049570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28291", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28291", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013146", "target": "P28291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKF1", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKF1", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023564", "target": "A5PKF1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA1", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA1", "target": "species_10049568" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA1", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009446", "target": "Q17QA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGB8", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGB8", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004257", "target": "E1BGB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P82943", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P82943", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013399", "target": "P82943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTV3", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTV3", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071668", "target": "A0A3Q1LTV3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NB11", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NB11", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085385", "target": "A0A3Q1NB11" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYS4", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYS4", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035430", "target": "F1MYS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTS6", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTS6", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005406", "target": "Q9TTS6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIF0", "target": "species_10049566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIF0", "target": "species_10049568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001579", "target": "F1MIF0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTZ4", "target": "species_10049568" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045156", "target": "species_10045154" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045142", "target": "reaction_10045156" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025420", "target": "species_10045142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025420", "target": "D9ZDE4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045152", "target": "reaction_10045156" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ86", "target": "species_10045152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ86", "target": "species_10045154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ86", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ86", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019846", "target": "F1MZ86" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6YT15", "target": "species_10045152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6YT15", "target": "species_10045154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6YT15", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6YT15", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002036", "target": "A6YT15" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D9ZDE4", "target": "species_10045154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D9ZDE4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D9ZDE4", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049639", "target": "species_10046163" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046161", "target": "reaction_10049639" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011164", "target": "species_10046161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011164", "target": "Q56JW7" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046157", "target": "reaction_10049639" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063808", "target": "species_10046157" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063808", "target": "G3N3U0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3U0", "target": "species_10046163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3U0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3U0", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JW7", "target": "species_10046163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JW7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JW7", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045094", "target": "species_10045092" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045090", "target": "reaction_10045094" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079349", "target": "species_10045090" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079349", "target": "A0A3Q1M976" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045086", "target": "reaction_10045094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP45", "target": "species_10045086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP45", "target": "species_10045092" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP45", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP45", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP45", "target": "species_10061655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018066", "target": "A0A3S5ZP45" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018066", "target": "species_10045084" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN72", "target": "species_10045086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN72", "target": "species_10045092" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN72", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN72", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025880", "target": "A0JN72" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M976", "target": "species_10045092" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M976", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M976", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091037", "target": "species_10091035" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9615246", "target": "reaction_10091037" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045250", "target": "reaction_10091037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063575", "target": "species_10045250" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063575", "target": "P25104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25104", "target": "species_10091035" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046731", "target": "species_10045816" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045814", "target": "reaction_10046731" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045814", "target": "reaction_10047483" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076190", "target": "species_10045814" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076190", "target": "A0A3Q1LXY0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045810", "target": "reaction_10046731" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PV87", "target": "species_10045810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PV87", "target": "species_10045816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PV87", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PV87", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009443", "target": "F6PV87" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME85", "target": "species_10045810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME85", "target": "species_10045816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME85", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME85", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022994", "target": "F1ME85" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10045816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10047481" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10085114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10051868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXY0", "target": "species_10051872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047483", "target": "species_10047481" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047479", "target": "reaction_10047483" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065044", "target": "species_10047479" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065044", "target": "P48044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48044", "target": "species_10047481" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48044", "target": "species_10085112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48044", "target": "species_10085114" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046733", "target": "species_10045972" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045970", "target": "reaction_10046733" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026346", "target": "species_10045970" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026346", "target": "P56449" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045966", "target": "reaction_10046733" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010554", "target": "species_10045966" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010554", "target": "P01175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01175", "target": "species_10045972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01175", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01175", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56449", "target": "species_10045972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56449", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56449", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049661", "target": "species_10046038" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046036", "target": "reaction_10049661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013959", "target": "species_10046036" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013959", "target": "F1MN36" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046032", "target": "reaction_10049661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021097", "target": "species_10046032" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021097", "target": "Q8SPN1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPN1", "target": "species_10046038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPN1", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPN1", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN36", "target": "species_10046038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN36", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN36", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046729", "target": "species_10045946" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045940", "target": "reaction_10046729" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029067", "target": "species_10045940" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029067", "target": "P08858" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045944", "target": "reaction_10046729" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021612", "target": "species_10045944" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021612", "target": "F1N2X0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2X0", "target": "species_10045946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2X0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2X0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08858", "target": "species_10045946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08858", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08858", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045406", "target": "species_10045404" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045398", "target": "reaction_10045406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8MJV4", "target": "species_10045398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8MJV4", "target": "species_10045404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8MJV4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8MJV4", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018455", "target": "Q8MJV4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH9", "target": "species_10045398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH9", "target": "species_10045404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH9", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078382", "target": "A0A3Q1LTH9" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045402", "target": "reaction_10045406" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021510", "target": "species_10045402" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021510", "target": "G5E5J0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5J0", "target": "species_10045404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5J0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5J0", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045362", "target": "species_10045360" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045358", "target": "reaction_10045362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084136", "target": "species_10045358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084136", "target": "A0A3Q1LWC2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045354", "target": "reaction_10045362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000695", "target": "species_10045354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000695", "target": "O62647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62647", "target": "species_10045360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62647", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62647", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWC2", "target": "species_10045360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWC2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWC2", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046773", "target": "species_10046771" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046769", "target": "reaction_10046773" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046767", "target": "reaction_10046773" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014661", "target": "species_10046767" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014661", "target": "P34974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34974", "target": "species_10046771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10046771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10046761" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10045320" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10045322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01190", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045332", "target": "species_10045330" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038198", "target": "reaction_10045332" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045328", "target": "reaction_10045332" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078035", "target": "species_10045328" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078035", "target": "A0A3Q1MXN7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXN7", "target": "species_10045330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXN7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXN7", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXN7", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXN7", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053335", "target": "species_10046116" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046114", "target": "reaction_10053335" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061371", "target": "species_10046114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061371", "target": "E1BP23" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046110", "target": "reaction_10053335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY53", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023519", "target": "F1MY53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII4", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014782", "target": "A0A452DII4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014782", "target": "species_10046098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP23", "target": "species_10046116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP23", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP23", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP23", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP23", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054775", "target": "species_10046104" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046102", "target": "reaction_10054775" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048447", "target": "species_10046102" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048447", "target": "A0A452DKE4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046098", "target": "reaction_10054775" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKE4", "target": "species_10046104" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKE4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKE4", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKE4", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKE4", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046953", "target": "species_10045986" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045984", "target": "reaction_10046953" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10045984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10045986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037563" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCC4", "target": "species_10037569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012283", "target": "F1MCC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10045984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10045986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10047878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4J9", "target": "species_10047884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026902", "target": "F1N4J9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026902", "target": "species_10047872" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026902", "target": "species_10092295" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026902", "target": "species_10092297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10045984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10045986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037563" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFB7", "target": "species_10037569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001191", "target": "A4IFB7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10046953" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10090718" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10090185" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10038221" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10092299" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10037580" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10037923" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037577", "target": "reaction_10037845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037577" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10045986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10038217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10038215" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037829" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037843" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10038219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI66", "target": "species_10037835" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009406", "target": "A0A452DI66" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009406", "target": "species_10038436" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009406", "target": "species_10038384" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009406", "target": "species_10037763" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009406", "target": "species_10037765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045384", "target": "species_10045382" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045366", "target": "reaction_10045384" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063299", "target": "species_10045366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063299", "target": "G3N364" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045380", "target": "reaction_10045384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV6", "target": "species_10045380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV6", "target": "species_10045382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008645", "target": "E1BFV6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10045380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10045382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT4", "target": "species_10072449" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011728", "target": "G3MWT4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV99", "target": "species_10045380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV99", "target": "species_10045382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV99", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV99", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052225", "target": "F1MV99" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N364", "target": "species_10045382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N364", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N364", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046763", "target": "species_10046761" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046759", "target": "reaction_10046763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P47798", "target": "species_10046759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P47798", "target": "species_10046761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032494", "target": "P47798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8V8", "target": "species_10046759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8V8", "target": "species_10046761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006185", "target": "E1B8V8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GLJ8", "target": "species_10046759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GLJ8", "target": "species_10046761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026223", "target": "Q9GLJ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56451", "target": "species_10046759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56451", "target": "species_10046761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012049", "target": "P56451" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046737", "target": "reaction_10046763" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049645", "target": "species_10046028" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046022", "target": "reaction_10049645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067360", "target": "species_10046022" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067360", "target": "A0A3Q1MSN3" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046026", "target": "reaction_10049645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018290", "target": "species_10046026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018290", "target": "F1MJZ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJZ0", "target": "species_10046028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJZ0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJZ0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSN3", "target": "species_10046028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSN3", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSN3", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049699", "target": "species_10049697" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049687", "target": "reaction_10049699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020135", "target": "species_10049687" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020135", "target": "E1BKC2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049695", "target": "reaction_10049699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77801", "target": "species_10049695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77801", "target": "species_10049697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027848", "target": "O77801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKC2", "target": "species_10049697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049683", "target": "species_10046335" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046333", "target": "reaction_10049683" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055041", "target": "species_10046333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055041", "target": "F1MSU3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046329", "target": "reaction_10049683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV7", "target": "species_10046329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV7", "target": "species_10046335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEV7", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036249", "target": "F1MEV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSU3", "target": "species_10046335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSU3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSU3", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045292", "target": "species_10045290" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045284", "target": "reaction_10045292" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004179", "target": "species_10045284" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004179", "target": "F1N018" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045288", "target": "reaction_10045292" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026275", "target": "species_10045288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026275", "target": "P79255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79255", "target": "species_10045290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N018", "target": "species_10045290" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045324", "target": "species_10045322" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045302", "target": "reaction_10045324" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N083", "target": "species_10045302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N083", "target": "species_10045322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N083", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N083", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004157", "target": "F1N083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIP6", "target": "species_10045302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIP6", "target": "species_10045322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIP6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIP6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001209", "target": "Q2KIP6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045320", "target": "reaction_10045324" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046735", "target": "species_10045888" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045876", "target": "reaction_10046735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17322", "target": "species_10045876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17322", "target": "species_10045888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17322", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17322", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010649", "target": "P17322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q867A9", "target": "species_10045876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q867A9", "target": "species_10045888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q867A9", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q867A9", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028571", "target": "Q867A9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045886", "target": "reaction_10046735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21450", "target": "species_10045886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21450", "target": "species_10045888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21450", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21450", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018173", "target": "P21450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28088", "target": "species_10045886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28088", "target": "species_10045888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28088", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28088", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070002", "target": "P28088" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046915", "target": "species_10046295" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046293", "target": "reaction_10046915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B1H0W3", "target": "species_10046293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B1H0W3", "target": "species_10046295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B1H0W3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B1H0W3", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022125", "target": "B1H0W3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKB6", "target": "species_10046293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKB6", "target": "species_10046295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKB6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKB6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006247", "target": "F1MKB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQX6", "target": "species_10046293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQX6", "target": "species_10046295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQX6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQX6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057526", "target": "A6QQX6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMU8", "target": "species_10046293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMU8", "target": "species_10046295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMU8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMU8", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087149", "target": "Q1RMU8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046275", "target": "reaction_10046915" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062944", "target": "species_10046275" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062944", "target": "P51694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51694", "target": "species_10046295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51694", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51694", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046917", "target": "species_10045962" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045950", "target": "reaction_10046917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006980", "target": "species_10045950" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006980", "target": "P01156" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045960", "target": "reaction_10046917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWG2", "target": "species_10045960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWG2", "target": "species_10045962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWG2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWG2", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028963", "target": "F1MWG2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ7", "target": "species_10045960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ7", "target": "species_10045962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ7", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ7", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004808", "target": "E1BCZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01156", "target": "species_10045962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01156", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01156", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049637", "target": "species_10046018" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046006", "target": "reaction_10049637" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006982", "target": "species_10046006" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006982", "target": "A6QM11" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046002", "target": "reaction_10049637" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026634", "target": "species_10046002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026634", "target": "O46639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46639", "target": "species_10046018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46639", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46639", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QM11", "target": "species_10046018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QM11", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QM11", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046919", "target": "species_10045904" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045902", "target": "reaction_10046919" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028248", "target": "species_10045902" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028248", "target": "E1BFS5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045898", "target": "reaction_10046919" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073562", "target": "species_10045898" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073562", "target": "A0A3Q1MXY0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXY0", "target": "species_10045904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXY0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXY0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFS5", "target": "species_10045904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFS5", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFS5", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045350", "target": "species_10045348" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045346", "target": "reaction_10045350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039541", "target": "species_10045346" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039541", "target": "A6QL98" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045336", "target": "reaction_10045350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026630", "target": "species_10045336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026630", "target": "A0A452DJT3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJT3", "target": "species_10045348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJT3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJT3", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL98", "target": "species_10045348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL98", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL98", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047864", "target": "species_10045828" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045826", "target": "reaction_10047864" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008730", "target": "species_10045826" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008730", "target": "A6QL49" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417891", "target": "reaction_10047864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10045828" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417891", "target": "reaction_10047851" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10045840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417891", "target": "reaction_10047860" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10045846" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417891", "target": "reaction_10078536" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417891", "target": "reaction_10048176" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10045924" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_417891", "target": "species_5696037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL49", "target": "species_10045828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL49", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QL49", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047851", "target": "species_10045840" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045838", "target": "reaction_10047851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004269", "target": "species_10045838" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004269", "target": "A4IFV1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFV1", "target": "species_10045840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFV1", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFV1", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047866", "target": "species_10045834" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417888", "target": "reaction_10047866" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417888", "target": "reaction_10047989" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045832", "target": "reaction_10047866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057184", "target": "species_10045832" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057184", "target": "F1MTB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTB2", "target": "species_10045834" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTB2", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTB2", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047853", "target": "species_10045978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114570", "target": "reaction_10047853" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114570", "target": "reaction_10048182" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045976", "target": "reaction_10047853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018000", "target": "species_10045976" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018000", "target": "F1MU50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU50", "target": "species_10045978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU50", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU50", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047868", "target": "species_10046217" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046215", "target": "reaction_10047868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054975", "target": "species_10046215" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054975", "target": "F1MDW9" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417877", "target": "reaction_10047868" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_10046217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_30595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_8936166" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_8851233" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_8851509" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29494", "target": "reaction_10035038" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29494", "target": "species_482807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDW9", "target": "species_10046217" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDW9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDW9", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090956", "target": "species_10047855" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9611319", "target": "reaction_10090956" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046221", "target": "reaction_10090956" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046221", "target": "reaction_10047857" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064076", "target": "species_10046221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064076", "target": "Q0IIL0" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10047855", "target": "reaction_10047857" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10047855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10046223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIL0", "target": "species_10047472" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047870", "target": "species_10045822" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114564", "target": "reaction_10047870" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114564", "target": "reaction_10047857" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045820", "target": "reaction_10047870" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001919", "target": "species_10045820" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001919", "target": "P48042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48042", "target": "species_10045822" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48042", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48042", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047857", "target": "species_10046223" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047989", "target": "species_10045894" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047860", "target": "species_10045846" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045844", "target": "reaction_10047860" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011278", "target": "species_10045844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011278", "target": "G3X6Q0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6Q0", "target": "species_10045846" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6Q0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6Q0", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047862", "target": "species_10046229" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046227", "target": "reaction_10047862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027950", "target": "species_10046227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027950", "target": "Q3SX17" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_417855", "target": "reaction_10047862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX17", "target": "species_10046229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX17", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX17", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047987", "target": "species_10046241" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046239", "target": "reaction_10047987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC81", "target": "species_10046239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC81", "target": "species_10046241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC81", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC81", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010057", "target": "Q0VC81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28190", "target": "species_10046239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28190", "target": "species_10046241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28190", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P28190", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072690", "target": "P28190" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83908", "target": "reaction_10047987" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83908", "target": "reaction_10048003" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_10046241" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_10048001" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179741" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_727774" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_727737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179738" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_500104" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83909", "target": "species_500173" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048003", "target": "species_10048001" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047999", "target": "reaction_10048003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZD0", "target": "species_10047999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZD0", "target": "species_10048001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009974", "target": "Q1LZD0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU0", "target": "species_10047999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU0", "target": "species_10048001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077466", "target": "E1BKU0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048001", "target": "reaction_10074833" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078536", "target": "species_109277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078536", "target": "species_6797635" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078533", "target": "reaction_10078536" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025329", "target": "species_10078533" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048176", "target": "species_10045924" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045922", "target": "reaction_10048176" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10045922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10045924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLD8", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071208", "target": "E1BLD8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10045922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10045924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX11", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004931", "target": "F1MX11" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10045922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10045924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC80", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005968", "target": "Q3ZC80" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10045922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10045924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9C6", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087152", "target": "A0A3Q1M9C6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048180", "target": "species_10046321" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046319", "target": "reaction_10048180" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME98", "target": "species_10046319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME98", "target": "species_10046321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME98", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME98", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000492", "target": "F1ME98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV28", "target": "species_10046319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV28", "target": "species_10046321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV28", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV28", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004608", "target": "F1MV28" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV6", "target": "species_10046319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV6", "target": "species_10046321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003550", "target": "A2VDV6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049663", "target": "species_10046076" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046074", "target": "reaction_10049663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J0", "target": "species_10046074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J0", "target": "species_10046076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J0", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007420", "target": "G3X6J0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQB3", "target": "species_10046074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQB3", "target": "species_10046076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQB3", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQB3", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024480", "target": "Q1JQB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB13", "target": "species_10046074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB13", "target": "species_10046076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB13", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB13", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016931", "target": "A7MB13" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46685", "target": "species_10046074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46685", "target": "species_10046076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46685", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46685", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008858", "target": "O46685" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084702", "target": "species_10084700" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9023982", "target": "reaction_10084702" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:81559", "target": "species_9023982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:81559", "target": "species_10084700" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9022660", "target": "species_9023982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9022660", "target": "species_10084700" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9022660", "target": "reaction_10090440" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084698", "target": "reaction_10084702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029488", "target": "species_10084698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029488", "target": "B9VR26" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9VR26", "target": "species_10084700" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051217", "target": "species_10046341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_517533", "target": "reaction_10051217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_517533", "target": "species_10046341" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_517533", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_517533", "target": "species_10046513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046339", "target": "reaction_10051217" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007469", "target": "species_10046339" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007469", "target": "Q3T0E9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0E9", "target": "species_10046341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0E9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0E9", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048178", "target": "species_10046257" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444560", "target": "reaction_10048178" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426030", "target": "species_444560" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426030", "target": "species_10046257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426030", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426030", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426030", "target": "reaction_10048587" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046255", "target": "reaction_10048178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9P2", "target": "species_10046255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9P2", "target": "species_10046257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9P2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9P2", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025809", "target": "E1B9P2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGC0", "target": "species_10046255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGC0", "target": "species_10046257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGC0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGC0", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067697", "target": "A0A3Q1LGC0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053333", "target": "species_10046449" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_561075", "target": "reaction_10053333" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046447", "target": "reaction_10053333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035454", "target": "species_10046447" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035454", "target": "F1MYN3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYN3", "target": "species_10046449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYN3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYN3", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067350", "target": "species_10046443" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_433123", "target": "reaction_10067350" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046441", "target": "reaction_10067350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068791", "target": "species_10046441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068791", "target": "A0A3Q1M1U4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1U4", "target": "species_10046443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1U4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1U4", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113536", "target": "species_10046443" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113536", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113536", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049641", "target": "species_10046136" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046134", "target": "reaction_10049641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065884", "target": "species_10046134" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065884", "target": "G3MWJ9" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10049641" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10038205" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10078759" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10080842" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10080831" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10049433" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10049464" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10049440" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_158417", "target": "reaction_10044634" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWJ9", "target": "species_10046136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWJ9", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWJ9", "target": "species_10046142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048172", "target": "species_10046271" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419339", "target": "reaction_10048172" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419339", "target": "species_10046271" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419339", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419339", "target": "species_10046513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046269", "target": "reaction_10048172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068939", "target": "species_10046269" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068939", "target": "A0A3Q1MJK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJK4", "target": "species_10046271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJK4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJK4", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081580", "target": "species_10081578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6805204", "target": "reaction_10081580" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6805204", "target": "species_10081578" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081576", "target": "reaction_10081580" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021281", "target": "species_10081576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021281", "target": "F1N600" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N600", "target": "species_10081578" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067362", "target": "species_10046465" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_3296330", "target": "reaction_10067362" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37098", "target": "species_3296330" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37098", "target": "species_10046465" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37098", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37098", "target": "species_10046513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046463", "target": "reaction_10067362" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067364", "target": "species_10046455" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046453", "target": "reaction_10067364" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001202", "target": "species_10046453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001202", "target": "B9UM28" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_373863", "target": "reaction_10067364" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_10046455" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_429748" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_8876310" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_373863", "target": "species_8876304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9UM28", "target": "species_10046455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9UM28", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B9UM28", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048174", "target": "species_10045998" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419375", "target": "reaction_10048174" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419375", "target": "species_10045998" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419375", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_419375", "target": "species_10046142" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045996", "target": "reaction_10048174" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038757", "target": "species_10045996" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038757", "target": "Q9TTY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10045998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTY5", "target": "species_10079651" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083937", "target": "species_10046485" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8851675", "target": "reaction_10083937" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046483", "target": "reaction_10083937" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007471", "target": "species_10046483" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007471", "target": "Q1RMI1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI1", "target": "species_10046485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMI1", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192184", "target": "species_10046485" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192184", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192184", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049643", "target": "species_10046503" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046501", "target": "reaction_10049643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5V2", "target": "species_10046501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5V2", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5V2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5V2", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038240", "target": "F1N5V2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NND8", "target": "species_10046501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NND8", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NND8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NND8", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084207", "target": "A0A3Q1NND8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444679", "target": "reaction_10049643" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32111", "target": "species_444679" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32111", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32111", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32111", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188980", "target": "species_444679" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188980", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188980", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188980", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188980", "target": "reaction_10040620" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5696361", "target": "species_444679" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5696361", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5696361", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5696361", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696361", "target": "reaction_10076974" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16296", "target": "species_444679" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16296", "target": "species_10046503" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16296", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16296", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045138", "target": "species_10045136" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045134", "target": "reaction_10045138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAB4", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAB4", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAB4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAB4", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001415", "target": "E1BAB4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJN2", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJN2", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJN2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJN2", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072365", "target": "A0A3Q1LJN2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7D8", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7D8", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7D8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7D8", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025275", "target": "A5D7D8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B965", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B965", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B965", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B965", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018119", "target": "E1B965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE8", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE8", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE8", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLE8", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017342", "target": "E1BLE8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10045134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10045136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10078458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDE0", "target": "species_10078462" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085376", "target": "F1MDE0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085376", "target": "species_10045110" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067348", "target": "species_10046437" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046435", "target": "reaction_10067348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK0", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK0", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVK0", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045470", "target": "F1MVK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N090", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N090", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N090", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N090", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071230", "target": "A0A3Q1N090" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP17", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP17", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP17", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP17", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001761", "target": "F1MP17" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB3", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB3", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB3", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043009", "target": "Q2ABB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA2", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA2", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA2", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079249", "target": "A0A3Q1LRA2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Q7", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Q7", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Q7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Q7", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082851", "target": "A0A3Q1N0Q7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZD2", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZD2", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZD2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZD2", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033179", "target": "F1MZD2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML22", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML22", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML22", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML22", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071900", "target": "A0A3Q1ML22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G6", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G6", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G6", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G6", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043010", "target": "F1N2G6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB1", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB1", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABB1", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031637", "target": "Q2ABB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC5", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC5", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC5", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC5", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046105", "target": "Q2ABC5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B7", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B7", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B7", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055191", "target": "E1B8B7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC4", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC4", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC4", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC4", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022454", "target": "Q2ABC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC0", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC0", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC0", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC0", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042999", "target": "Q2ABC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZA1", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZA1", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZA1", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZA1", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076866", "target": "A0A3Q1LZA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIP5", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIP5", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIP5", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIP5", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071184", "target": "A0A3Q1MIP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC3", "target": "species_10046435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC3", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC3", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2ABC3", "target": "species_10046513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024537", "target": "Q2ABC3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_3296423", "target": "reaction_10067348" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3193", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3193", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3193", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3193", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76328", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76328", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76328", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76328", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76328", "target": "reaction_10044167" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76328", "target": "reaction_10035878" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3768", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3768", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3768", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3768", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:10093", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:10093", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:10093", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:10093", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17814", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17814", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17814", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17814", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_40727", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_40727", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_40727", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_40727", "target": "species_10046513" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_40727", "target": "reaction_10035865" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8206", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8206", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8206", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8206", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48923", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48923", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48923", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:48923", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28973", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28973", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28973", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28973", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73228", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73228", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73228", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73228", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:23359", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:23359", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:23359", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:23359", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28241", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28241", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28241", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28241", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73226", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73226", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73226", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73226", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73224", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73224", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73224", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73224", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65408", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65408", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65408", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65408", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3944", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3944", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3944", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3944", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73235", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73235", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73235", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73235", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73231", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73231", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73231", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73231", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16226", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16226", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16226", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16226", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27613", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27613", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27613", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27613", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:5547", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:5547", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:5547", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:5547", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2825", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2825", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2825", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2825", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73232", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73232", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73232", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73232", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18305", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18305", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18305", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18305", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3445", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3445", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3445", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3445", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36773", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36773", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36773", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36773", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2622", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2622", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2622", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2622", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73237", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73237", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73237", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73237", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2366", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2366", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2366", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2366", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3941", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3941", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3941", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:3941", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:7939", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:7939", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:7939", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:7939", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:351346", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:351346", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:351346", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:351346", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8692", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8692", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8692", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8692", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73239", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73239", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73239", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73239", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15854", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:9162", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:9162", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:9162", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:9162", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26948", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26948", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26948", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:26948", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50042", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50042", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50042", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:50042", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:69236", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:69236", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:69236", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:69236", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73222", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73222", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73222", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73222", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17698", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17698", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17698", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17698", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73236", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73236", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73236", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:73236", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2853", "target": "species_3296423" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2853", "target": "species_10046437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2853", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2853", "target": "species_10046513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089211", "target": "species_10089209" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039640", "target": "reaction_10089211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10088937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCA7", "target": "species_10047472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017303", "target": "Q3ZCA7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10088937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63097", "target": "species_10047472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003515", "target": "P63097" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10088937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH9", "target": "species_10047472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027511", "target": "A7MBH9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10088932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10088937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10039642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10046721" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G1K1V2", "target": "species_10047472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023234", "target": "G1K1V2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089193", "target": "reaction_10089211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46471", "target": "species_10089205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005642", "target": "O46471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFC7", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFC7", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFC7", "target": "species_10089195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075674", "target": "A0A3Q1MFC7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7H3", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7H3", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7H3", "target": "species_10089195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037643", "target": "E1B7H3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10047977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMB5", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048654", "target": "E1BMB5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG6", "target": "species_10089205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012221", "target": "A7MBG6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMH1", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMH1", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMH1", "target": "species_10089195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022048", "target": "F1MMH1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR0", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028880", "target": "F1MUR0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10047977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R3", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005904", "target": "F1N7R3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79348", "target": "species_10089205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004487", "target": "P79348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIV2", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIV2", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIV2", "target": "species_10089195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011200", "target": "E1BIV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2W6", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070104", "target": "A0A3Q1N2W6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH23", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054620", "target": "E1BH23" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089209", "target": "reaction_10089214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089197", "target": "species_10039660" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089197", "target": "species_10089193" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089195", "target": "reaction_10089197" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088940", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088940", "target": "species_10088937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088932", "target": "reaction_10088940" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088937", "target": "reaction_10088942" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088942", "target": "species_10088935" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088942", "target": "species_10039640" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089214", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089214", "target": "species_10089195" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048370", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048370", "target": "species_10048367" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048361", "target": "reaction_10048370" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10048367" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10046509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10046513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10047495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10051653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10037407" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10083229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10083806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10037427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10037431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10049028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10049032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10049009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10049011" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10047470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P63212", "target": "species_10047472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003959", "target": "P63212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04695", "target": "species_10048361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04695", "target": "species_10048367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023990", "target": "P04695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023990", "target": "species_10065796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023990", "target": "species_10065799" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037037", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037034", "target": "reaction_10037037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6Q5", "target": "species_10037034" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6Q5", "target": "species_10047944" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072751", "target": "A0A3Q1N6Q5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5T6", "target": "species_10037034" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5T6", "target": "species_10047944" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014100", "target": "F1N5T6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039658", "target": "species_10039655" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039620", "target": "reaction_10039658" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039620", "target": "reaction_10039653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039662" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D6", "target": "species_10039648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079386", "target": "A0A3Q1M3D6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039655", "target": "reaction_10039674" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039655", "target": "reaction_10039667" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039674", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039674", "target": "species_10039669" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039669", "target": "reaction_10039671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039667", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039667", "target": "species_30389" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039671", "target": "species_10036997" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039671", "target": "species_10039646" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036959", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036959", "target": "species_112275" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_114520", "target": "species_10037546" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114520", "target": "reaction_10060986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114520", "target": "reaction_10060917" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036956", "target": "reaction_10036959" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036956", "target": "reaction_10037045" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036956", "target": "reaction_10037549" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVV4", "target": "species_10036956" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVV4", "target": "species_10037544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVV4", "target": "species_10037546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVV4", "target": "species_10061003" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074229", "target": "A0A3Q1LVV4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074229", "target": "species_10036942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037045", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037045", "target": "species_10037043" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037045", "target": "species_10036942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039676", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039676", "target": "species_10039662" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039644", "target": "reaction_10039676" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039644", "target": "reaction_10039651" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039662", "target": "reaction_10039664" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039664", "target": "species_10036997" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039664", "target": "species_10039646" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039664", "target": "species_10039660" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039651", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039651", "target": "species_10039648" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039653", "target": "species_10039644" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039642", "target": "reaction_10039653" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046534", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046534", "target": "species_10046513" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046509", "target": "reaction_10046534" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10046532", "target": "reaction_10046534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMQ2", "target": "species_10046532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081300", "target": "A0A3Q1MMQ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKT3", "target": "species_10046532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078547", "target": "A0A3Q1MKT3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089224", "target": "species_10089199" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089224", "target": "species_10037355" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089219", "target": "reaction_10089224" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V3", "target": "species_10089219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V3", "target": "species_10089199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V3", "target": "species_10047977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V3", "target": "species_10089201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026460", "target": "F1N3V3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089199", "target": "reaction_10089203" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047979", "target": "species_10037355" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047977", "target": "reaction_10047979" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048632", "target": "species_10048630" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048628", "target": "reaction_10048632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W2", "target": "species_10048628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W2", "target": "species_10048630" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4W2", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077611", "target": "A0A3Q1M4W2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTG6", "target": "species_10048628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTG6", "target": "species_10048630" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTG6", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070979", "target": "A0A3Q1LTG6" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114519", "target": "reaction_10048632" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114519", "target": "reaction_10048543" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114519", "target": "reaction_10048580" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114519", "target": "reaction_10048660" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048630", "target": "reaction_10048635" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048543", "target": "species_10048541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048539", "target": "reaction_10048543" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY82", "target": "species_10048539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY82", "target": "species_10048541" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004240", "target": "F1MY82" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10048539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10048541" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10043223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10043202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10043209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG4", "target": "species_10066178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060978", "target": "E1BMG4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060978", "target": "species_10043006" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048587", "target": "species_422506" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048587", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048587", "target": "species_76116" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048584", "target": "reaction_10048587" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073448", "target": "species_10048584" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073448", "target": "A0A3Q1LUK0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048580", "target": "species_426026" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048580", "target": "species_426030" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048577", "target": "reaction_10048580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBV2", "target": "species_10048577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018523", "target": "E1BBV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RA94", "target": "species_10048577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012173", "target": "F6RA94" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076743", "target": "species_422506" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076743", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076743", "target": "species_76116" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5694509", "target": "reaction_10076743" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076740", "target": "reaction_10076743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022100", "target": "species_10076740" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048660", "target": "species_76108" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048660", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048657", "target": "reaction_10048660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCG9", "target": "species_10048657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031198", "target": "F1MCG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJA6", "target": "species_10048657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066461", "target": "A0A3Q1NJA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGA9", "target": "species_10048657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022905", "target": "E1BGA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYT4", "target": "species_10048657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075621", "target": "A0A3Q1LYT4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4W0", "target": "species_10048657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080144", "target": "A0A3Q1N4W0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037549", "target": "species_10037546" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037544", "target": "reaction_10037549" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047823", "target": "species_10047821" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047819", "target": "reaction_10047823" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064910", "target": "species_10064908" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040201", "target": "reaction_10064910" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040201", "target": "reaction_10091705" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040201", "target": "reaction_10040323" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064908", "target": "reaction_10064919" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064915", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064915", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064912", "target": "reaction_10064915" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064919", "target": "species_10064912" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089203", "target": "species_10089201" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089201", "target": "reaction_10089222" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046149", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046149", "target": "species_10046142" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046140", "target": "reaction_10046149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B5U8Y5", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B5U8Y5", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014446", "target": "B5U8Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDJ6", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDJ6", "target": "species_10046142" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "Q9BDJ6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048434" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048438" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048421" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048413" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048423" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10046085" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048398" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016350", "target": "species_10048400" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28716", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28716", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28716", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28875", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28875", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28875", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28875", "target": "species_6803778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53460", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53460", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53460", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27997", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27997", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27997", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024011", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024011", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9024011", "target": "species_10046130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090508" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090392" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090394" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024011", "target": "reaction_10090384" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53487", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53487", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53487", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53486", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53486", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:53486", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8934421", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8934421", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8934421", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8934421", "target": "species_6803778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9608444", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9608444", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9608444", "target": "species_10046130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9608444", "target": "reaction_10090477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9608444", "target": "reaction_10090470" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9608444", "target": "reaction_10090472" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9608444", "target": "reaction_10090506" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28661", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28661", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28661", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2026977", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2026977", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2026977", "target": "species_10046130" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2026977", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2026977", "target": "species_10047805" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2026977", "target": "reaction_10090510" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2026977", "target": "reaction_10090377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKC0", "target": "species_10046140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKC0", "target": "species_10046142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKC0", "target": "species_10046130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000560", "target": "E1BKC0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046146", "target": "reaction_10046149" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089222", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089222", "target": "species_10089219" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047947", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047944", "target": "reaction_10047947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ56", "target": "species_10047944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ56", "target": "species_10047927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078870", "target": "A0A3Q1MZ56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MW13", "target": "species_10047944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MW13", "target": "species_10047927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079827", "target": "A0A3Q1MW13" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPD8", "target": "species_10047944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPD8", "target": "species_10047927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021805", "target": "E1BPD8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3R2", "target": "species_10047944" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085287", "target": "A0A3Q1M3R2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5L1", "target": "species_10047944" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082666", "target": "A0A3Q1M5L1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089226", "target": "species_10083941" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089226", "target": "species_10084012" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083948", "target": "reaction_10089226" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP29", "target": "species_10083948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP29", "target": "species_10083943" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061163", "target": "E1BP29" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061163", "target": "species_10083941" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083941", "target": "reaction_10089228" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084012", "target": "reaction_10084016" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089228", "target": "species_10083943" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083943", "target": "reaction_10083951" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091247", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091244", "target": "reaction_10091247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072849", "target": "species_10091244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083951", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083951", "target": "species_10083948" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084016", "target": "species_10084014" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047876", "target": "reaction_10084016" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047876", "target": "reaction_10047880" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047876", "target": "reaction_10085116" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050078", "target": "species_10047876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050078", "target": "G3X811" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X811", "target": "species_10084014" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X811", "target": "species_10047878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X811", "target": "species_10047884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X811", "target": "species_10085114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092055", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10092052", "target": "reaction_10092055" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047498", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047498", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047495", "target": "reaction_10047498" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10047495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10047493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L5", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080364", "target": "A0A3Q1M2L5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10047495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10047493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCV1", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007845", "target": "E1BCV1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043315", "target": "species_10043313" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037311", "target": "reaction_10043315" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088962", "target": "species_10088960" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047596", "target": "reaction_10088962" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048105", "target": "reaction_10088962" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048105", "target": "reaction_10049312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083031", "target": "species_10048105" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083031", "target": "A0A3Q1LKT5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT5", "target": "species_10088960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT5", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKT5", "target": "species_10049310" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051656", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051656", "target": "species_10051653" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051649", "target": "reaction_10051656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10051649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10051653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10047464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10047466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10089165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10089205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM27", "target": "species_10051645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074311", "target": "A0A3Q1MM27" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047468", "target": "species_10047466" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047464", "target": "reaction_10047468" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047464", "target": "reaction_10089167" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089167", "target": "species_10089165" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089163", "target": "reaction_10089167" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089165", "target": "reaction_10089217" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089217", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089217", "target": "species_10089205" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089205", "target": "reaction_10089207" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089207", "target": "species_10051645" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089207", "target": "species_10089163" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048170", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048170", "target": "species_10047841" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047839", "target": "reaction_10048170" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048167", "target": "reaction_10048170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9G8", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014311", "target": "E1B9G8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA97", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081198", "target": "A0A3Q1MA97" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXW7", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081961", "target": "A0A3Q1LXW7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA22", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA22", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069238", "target": "A0A3Q1MA22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10048167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10047544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10047550" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10037327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10037321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10047953" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10049028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P3", "target": "species_10049032" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062941", "target": "G5E6P3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS5", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009131", "target": "Q58CS5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5H1", "target": "species_10048167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068004", "target": "A0A3Q1N5H1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047552", "target": "species_10047550" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047548", "target": "reaction_10047552" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047544", "target": "reaction_10047552" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047544", "target": "reaction_10047956" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIL1", "target": "species_10047544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIL1", "target": "species_10047550" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIL1", "target": "species_10047953" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023757", "target": "E1BIL1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051667", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051667", "target": "species_10051660" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051664", "target": "reaction_10051667" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037330", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037330", "target": "species_10037315" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037327", "target": "reaction_10037330" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037332", "target": "species_10037327" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037325", "target": "reaction_10037332" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037321", "target": "reaction_10037332" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047956", "target": "species_10047953" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072123", "target": "species_10072121" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072119", "target": "reaction_10072123" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072119", "target": "reaction_10072715" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075908", "target": "species_10072119" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075908", "target": "A0A3Q1LM07" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072115", "target": "reaction_10072123" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072121", "target": "reaction_10072220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM07", "target": "species_10072121" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072154", "target": "species_10072148" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072144", "target": "reaction_10072154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE57", "target": "species_10072144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE57", "target": "species_10072148" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017670", "target": "E1BE57" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10072152", "target": "reaction_10072154" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064817", "target": "species_10072152" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064817", "target": "species_10072602" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064817", "target": "species_10072604" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064817", "target": "G3N1D5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072220", "target": "species_10072165" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072079", "target": "reaction_10072220" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072079", "target": "reaction_10072715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H727", "target": "species_10072663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008704", "target": "A6H727" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072708" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCY1", "target": "species_10072663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015510", "target": "F1MCY1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDV1", "target": "species_10072079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDV1", "target": "species_10072165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDV1", "target": "species_10072130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDV1", "target": "species_10072135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDV1", "target": "species_10072173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068810", "target": "A0A3Q1MDV1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068810", "target": "species_10072077" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072165", "target": "reaction_10072199" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072218", "target": "reaction_10072220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE3", "target": "species_10072218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE3", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE3", "target": "species_10055641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE3", "target": "species_10055535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035821", "target": "E1BKE3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035821", "target": "species_10055533" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB3", "target": "species_10072218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078675", "target": "A0A3Q1MNB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KR5", "target": "species_10072218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087155", "target": "Q32KR5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR3", "target": "species_10072218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007606", "target": "A0A452DIR3" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072197", "target": "reaction_10072220" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072197", "target": "reaction_10072199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBF8", "target": "species_10072197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025532", "target": "E1BBF8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDL2", "target": "species_10072197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017038", "target": "F1MDL2" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072183", "target": "reaction_10072220" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072183", "target": "reaction_10072199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RVK1", "target": "species_10072183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049437", "target": "F6RVK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTC8", "target": "species_10072183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082308", "target": "A0A3Q1LTC8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072081", "target": "species_10072079" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072077", "target": "reaction_10072081" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072073", "target": "reaction_10072081" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072138", "target": "species_10072135" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072130", "target": "reaction_10072138" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072199", "target": "species_10072173" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072187", "target": "reaction_10072199" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036487", "target": "species_10072187" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072713", "target": "species_10072708" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072710", "target": "reaction_10072713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCW1", "target": "species_10072710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCW1", "target": "species_10072708" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007660", "target": "Q0VCW1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072715", "target": "species_10072165" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072685", "target": "species_10072683" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072669", "target": "reaction_10072685" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072681", "target": "reaction_10072685" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022205", "target": "species_10072681" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022205", "target": "E1BPQ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPQ8", "target": "species_10072683" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072606", "target": "species_10072604" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072602", "target": "reaction_10072606" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072720", "target": "species_10042973" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072720", "target": "species_10072602" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072718", "target": "reaction_10072720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1D5", "target": "species_10072718" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072677", "target": "species_10072663" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072675", "target": "reaction_10072677" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074038", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074038", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074035", "target": "reaction_10074038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI10", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI10", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI10", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI10", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073047", "target": "A0A3Q1LI10" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN5", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN5", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN5", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN5", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007787", "target": "E1BMN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE9", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE9", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE9", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE9", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006213", "target": "F1MKE9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMQ8", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMQ8", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMQ8", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMQ8", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061417", "target": "F1MMQ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10047443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10047447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC8", "target": "species_10047453" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066559", "target": "A0A3Q1LNC8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJB1", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044847", "target": "A0A452DJB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10058476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10091665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10058471" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10043817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10091749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX3", "target": "species_10057859" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003498", "target": "A0A452DHX3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003498", "target": "species_10043782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5N3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5N3", "target": "species_10073958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5N3", "target": "species_10073960" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021391", "target": "F1N5N3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP52", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP52", "target": "species_10073958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP52", "target": "species_10073960" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP52", "target": "species_10084389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP52", "target": "species_10084391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015112", "target": "F1MP52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10073999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084159" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S0Q2", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006816", "target": "F6S0Q2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10073999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084159" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKU1", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000528", "target": "E1BKU1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084159" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS00", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000744", "target": "F1MS00" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000744", "target": "species_10084137" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084159" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8H3", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083411", "target": "A0A3Q1N8H3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083411", "target": "species_10073976" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084159" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y1", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081398", "target": "A0A3Q1M0Y1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD76", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023553", "target": "E1BD76" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023553", "target": "species_10073972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCL0", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027984", "target": "E1BCL0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027984", "target": "species_10074013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10074027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10074025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084151" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10074031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10074029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM3", "target": "species_10084324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066172", "target": "G3MZM3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066172", "target": "species_10074017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSU3", "target": "species_10074035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSU3", "target": "species_10056236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068365", "target": "A0A3Q1LSU3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N010", "target": "species_10074035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084300", "target": "A0A3Q1N010" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091515", "target": "species_8848337" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091515", "target": "species_10091512" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039726", "target": "reaction_10091515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039726", "target": "reaction_10091527" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091502", "target": "reaction_10091515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091502", "target": "reaction_10091506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Z8", "target": "species_10091502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Z8", "target": "species_10091504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081950", "target": "A0A3Q1M5Z8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG2", "target": "species_10091502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG2", "target": "species_10091504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008957", "target": "A7MBG2" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10091504", "target": "reaction_10091515" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091458", "target": "species_10091454" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091458", "target": "species_71285" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091448", "target": "reaction_10091458" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091454", "target": "reaction_10091490" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077880", "target": "reaction_10091458" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077880", "target": "reaction_10077883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1V4", "target": "species_10077880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1V4", "target": "species_10091456" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064297", "target": "G3N1V4" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10091456", "target": "reaction_10091458" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091490", "target": "species_10091477" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091490", "target": "species_76194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091477", "target": "reaction_10091479" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091487", "target": "reaction_10091490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA55", "target": "species_10091487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA55", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA55", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069302", "target": "Q5EA55" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DA8", "target": "species_10091487" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075844", "target": "Q58DA8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091506", "target": "species_10091504" }, { "type": "reactant", "sub_type": "other", "source": "species_9647934", "target": "reaction_10091506" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091479", "target": "species_10039726" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091527", "target": "species_10040312" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074088", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074088", "target": "species_10074065" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074042", "target": "reaction_10074088" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074042", "target": "reaction_10091548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10073913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10073915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10074040" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10073938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10073936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI16", "target": "species_10074182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006653", "target": "A0A452DI16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10073919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10073927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10073925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10073869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10073863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074040" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQP3", "target": "species_10074121" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074936", "target": "A0A3Q1LQP3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10073919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10073927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10073925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10073869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10073863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074040" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M888", "target": "species_10074121" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079194", "target": "A0A3Q1M888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073896" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074040" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10073936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074213" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10074174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10090951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10090933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10090946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M353", "target": "species_10057312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086962", "target": "A0A3Q1M353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086962", "target": "species_10057310" }, { "type": "catalyst", "sub_type": "", "source": "species_10074085", "target": "reaction_10074088" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073930", "target": "species_10073927" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073930", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073919", "target": "reaction_10073930" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073927", "target": "reaction_10073932" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073917", "target": "species_10073915" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073913", "target": "reaction_10073917" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073913", "target": "reaction_10074184" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073915", "target": "reaction_10073942" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073932", "target": "species_10037668" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073932", "target": "species_10073925" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091548", "target": "species_10074135" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9657579", "target": "reaction_10091548" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074135", "target": "reaction_10074137" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073921", "target": "species_10073919" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073869", "target": "reaction_10073921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073904", "target": "species_10073898" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073896", "target": "reaction_10073904" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073898", "target": "reaction_10074050" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10073902", "target": "reaction_10073904" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070853", "target": "species_10073902" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073872", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073872", "target": "species_10073869" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073863", "target": "reaction_10073872" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073863", "target": "reaction_10074148" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074050", "target": "species_10074042" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074040", "target": "reaction_10074050" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074048", "target": "reaction_10074050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H716", "target": "species_10074048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H716", "target": "species_10074144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H716", "target": "species_10074153" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001552", "target": "A6H716" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001552", "target": "species_10074046" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073940", "target": "species_10037668" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073940", "target": "species_10073936" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073938", "target": "reaction_10073940" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073942", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073942", "target": "species_10073938" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074184", "target": "species_10074182" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074180", "target": "reaction_10074184" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071243", "target": "species_10074180" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071243", "target": "A0A3Q1M5M4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5M4", "target": "species_10074182" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074221", "target": "species_10074219" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074213", "target": "reaction_10074221" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074213", "target": "reaction_10074238" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074217", "target": "reaction_10074221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024107", "target": "species_10074217" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024107", "target": "P13696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13696", "target": "species_10074219" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074156", "target": "species_10074153" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074144", "target": "reaction_10074156" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074238", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074238", "target": "species_10074225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074225", "target": "reaction_10074231" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074235", "target": "reaction_10074238" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010538", "target": "species_10074235" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074146", "target": "species_10074144" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074046", "target": "reaction_10074146" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074046", "target": "reaction_10074148" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074148", "target": "species_10074048" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074231", "target": "species_10074229" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074231", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091534", "target": "species_10040312" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091580", "target": "species_10091578" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074137", "target": "species_10074114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074137", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074123", "target": "reaction_10074137" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074123", "target": "reaction_10091568" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10074192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD16", "target": "species_10090946" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048212", "target": "Q0VD16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10091574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074174" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10074192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10090935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10090937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPX3", "target": "species_10090946" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011377", "target": "A0A3S5ZPX3" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074114", "target": "reaction_10074129" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074114", "target": "reaction_10091570" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074114", "target": "reaction_10091572" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074125", "target": "reaction_10074137" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074125", "target": "reaction_10074129" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091576", "target": "species_10091574" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074118", "target": "reaction_10091576" }, { "type": "reactant", "sub_type": "", "source": "species_9657577", "target": "reaction_10091576" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074129", "target": "species_10074118" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074129", "target": "species_29370" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074127", "target": "reaction_10074129" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10074121", "target": "reaction_10074129" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091568", "target": "species_10074125" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9657567", "target": "reaction_10091568" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074176", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074176", "target": "species_10074174" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074172", "target": "reaction_10074176" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN2", "target": "species_10074172" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN2", "target": "species_10074174" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082130", "target": "Q0VCN2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074195", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074195", "target": "species_10074192" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074190", "target": "reaction_10074195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP15", "target": "species_10074190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP15", "target": "species_10074192" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060984", "target": "E1BP15" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091570", "target": "species_10074127" }, { "type": "reactant", "sub_type": "", "source": "species_9657570", "target": "reaction_10091570" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091572", "target": "species_10074121" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9657574", "target": "reaction_10091572" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091595", "target": "species_10091593" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091591", "target": "reaction_10091595" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091589", "target": "reaction_10091595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAC7", "target": "species_10091589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAC7", "target": "species_10091593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076160", "target": "A0A3Q1NAC7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Z6", "target": "species_10091589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Z6", "target": "species_10091593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Z6", "target": "species_10039734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087412", "target": "A0A3Q1M6Z6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087412", "target": "species_10039732" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091529", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091529", "target": "species_10039728" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075256", "target": "species_10075236" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075256", "target": "species_10075202" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075220", "target": "reaction_10075256" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVV5", "target": "species_10075194" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013073", "target": "F1MVV5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075202" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075214" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10076191" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10075194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E577", "target": "species_10076195" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007709", "target": "G5E577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007709", "target": "species_10076185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10075220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10075216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10075904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10075913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10066867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10066855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH23", "target": "species_10066853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "F1MH23" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "species_10075236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "species_10075208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "species_10075258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "species_10066851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012303", "target": "species_10066865" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075236", "target": "reaction_10075906" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075236", "target": "reaction_10075239" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075260", "target": "species_10075258" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075208", "target": "reaction_10075260" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075262", "target": "species_10075226" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075234", "target": "reaction_10075262" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075251", "target": "species_10075249" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075241", "target": "reaction_10075251" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075249", "target": "reaction_10075253" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075218", "target": "species_10075216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066851", "target": "reaction_10075218" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075214", "target": "reaction_10075218" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075216", "target": "reaction_10075223" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075253", "target": "species_10075241" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075223", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075223", "target": "species_10075220" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075916", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075916", "target": "species_10075913" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075904", "target": "reaction_10075916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MI00", "target": "species_10075904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MI00", "target": "species_10075913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MI00", "target": "species_10071238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MI00", "target": "species_10071205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036270", "target": "Q3MI00" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036270", "target": "species_10067944" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076193", "target": "species_10076191" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076189", "target": "reaction_10076193" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075652", "target": "species_10076189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075652", "target": "A0A3Q1MTC5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076185", "target": "reaction_10076193" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076191", "target": "reaction_10076198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTC5", "target": "species_10076191" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTC5", "target": "species_10076195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075906", "target": "species_10075904" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067944", "target": "reaction_10075906" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075205", "target": "species_10075202" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075205", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075194", "target": "reaction_10075205" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047654", "target": "reaction_10075205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047604" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10070674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0G8", "target": "species_10047614" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082239", "target": "A0A3Q1M0G8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10047654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10047612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10047614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSY0", "target": "species_10069208" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085260", "target": "A0A3Q1LSY0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076229", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076229", "target": "species_10076226" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042661", "target": "reaction_10076229" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042661", "target": "reaction_10091184" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061127", "target": "species_10042661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061127", "target": "species_10076226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061127", "target": "species_10042680" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061127", "target": "species_10044088" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061127", "target": "A0A452DJI7" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066865", "target": "reaction_10076229" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075239", "target": "species_10075234" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075239", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075232", "target": "reaction_10075239" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076198", "target": "species_113550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076198", "target": "species_10076195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039690", "target": "species_10039688" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039686", "target": "reaction_10039690" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039688", "target": "reaction_10039697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090954", "target": "species_10090933" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090954", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090951", "target": "reaction_10090954" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039711", "target": "species_10039709" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039703", "target": "reaction_10039711" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039697", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039697", "target": "species_10039694" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090944", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090944", "target": "species_10090937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090935", "target": "reaction_10090944" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090937", "target": "reaction_10090949" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090949", "target": "species_10090946" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090949", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039592", "target": "species_10039589" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039592", "target": "species_29420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039587", "target": "reaction_10039592" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039579", "target": "reaction_10039592" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039579", "target": "reaction_10039581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039581", "target": "species_10039579" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039601", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039601", "target": "species_10039579" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039598", "target": "reaction_10039601" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074879", "target": "species_10073960" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073958", "target": "reaction_10074879" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039736", "target": "species_10039734" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039732", "target": "reaction_10039736" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10040570", "target": "species_10040551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040570", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040546", "target": "reaction_10040570" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040551", "target": "reaction_10050366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040567", "target": "reaction_10040570" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090994", "target": "species_10090992" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090982", "target": "reaction_10090994" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008295", "target": "species_10090982" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008295", "target": "Q1RMU0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090978", "target": "reaction_10090994" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019612", "target": "species_10090978" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019612", "target": "F1N3F6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090990", "target": "reaction_10090994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C9", "target": "species_10090990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0C9", "target": "species_10090992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064240", "target": "G3N0C9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3F6", "target": "species_10090992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMU0", "target": "species_10090992" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041851", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041851", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041848", "target": "reaction_10041851" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041869", "target": "species_10041867" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041865", "target": "reaction_10041869" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10041917", "target": "species_10041915" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041913", "target": "reaction_10041917" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040489", "target": "species_10040480" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040476", "target": "reaction_10040489" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040476", "target": "reaction_10040495" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040480", "target": "reaction_10040495" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040486", "target": "reaction_10040489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCD7", "target": "species_10040486" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077745", "target": "A0A3Q1MCD7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077745", "target": "species_10077484" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040495", "target": "species_10039264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040495", "target": "species_10040493" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090722", "target": "species_10090720" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090663", "target": "reaction_10090722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT3", "target": "species_10090663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT3", "target": "species_10090720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT3", "target": "species_10090724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT3", "target": "species_10090654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT3", "target": "species_10090673" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013493", "target": "Q08DT3" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090411", "target": "reaction_10090722" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090720", "target": "reaction_10090727" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090727", "target": "species_10090724" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090727", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090666", "target": "species_10090663" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090666", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090654", "target": "reaction_10090666" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090675", "target": "species_10090663" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090675", "target": "species_10043237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090673", "target": "reaction_10090675" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073244", "target": "species_10073210" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040423", "target": "reaction_10073244" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040423", "target": "reaction_10073246" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040423", "target": "reaction_10073242" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040423", "target": "reaction_10073201" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073210", "target": "reaction_10073215" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073215", "target": "species_10073212" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057337", "target": "species_10057300" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057337", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057334", "target": "reaction_10057337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10053077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10053079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10057312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10053066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10053072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10040382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E39", "target": "species_10040384" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002324", "target": "Q08E39" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002324", "target": "species_10057306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002324", "target": "species_10040374" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10057334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10057300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10057316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10053062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10053066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ84", "target": "species_10053072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079589", "target": "A0A3Q1MJ84" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079589", "target": "A0A3Q1MJY7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10057334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10057300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10057316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10053062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10053066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJY7", "target": "species_10053072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10057334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10057300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10057316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10053062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10053066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P594", "target": "species_10053072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012182", "target": "Q0P594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10057334" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10057300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10057316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10057321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10053062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10053066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67774", "target": "species_10053072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000596", "target": "P67774" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057300", "target": "reaction_10057302" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057323", "target": "species_10057321" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057316", "target": "reaction_10057323" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057316", "target": "reaction_10057329" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057321", "target": "reaction_10059156" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053082", "target": "species_10053079" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053077", "target": "reaction_10053082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053079", "target": "reaction_10057327" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057327", "target": "species_10040359" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057327", "target": "species_10057325" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057329", "target": "species_10053062" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057329", "target": "species_10053077" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057314", "target": "species_10057310" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057314", "target": "species_10057306" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057312", "target": "reaction_10057314" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059156", "target": "species_10057316" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059156", "target": "species_10035485" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057302", "target": "species_10053066" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053066", "target": "reaction_10057318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057318", "target": "species_10057316" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057318", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040307", "target": "reaction_10057318" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040307", "target": "reaction_10040310" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040307", "target": "reaction_10072045" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10053072", "target": "reaction_10057318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040761", "target": "species_10040759" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040755", "target": "reaction_10040761" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036461", "target": "reaction_10040761" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040759", "target": "reaction_10040779" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040779", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040779", "target": "species_10036473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083933", "target": "species_205687" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083933", "target": "species_10083930" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10083933" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10052461" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10052690" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10084410" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10061642" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_735700", "target": "reaction_10090620" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083928", "target": "reaction_10083933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083930", "target": "reaction_10083935" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10052428", "target": "reaction_10083933" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018541", "target": "species_10052428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018541", "target": "E1BBP1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083935", "target": "species_10036373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040782", "target": "species_10036485" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040782", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040751", "target": "reaction_10040782" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040753", "target": "species_10040751" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040747", "target": "reaction_10040753" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036475", "target": "reaction_10040753" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073240", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073240", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065247", "target": "reaction_10073240" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073192", "target": "species_10073190" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073188", "target": "reaction_10073192" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035515", "target": "reaction_10073192" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035515", "target": "reaction_10073115" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035515", "target": "reaction_10092033" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035515", "target": "reaction_10092165" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073190", "target": "reaction_10073237" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073237", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073237", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073177", "target": "species_10073170" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073168", "target": "reaction_10073177" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073168", "target": "reaction_10073184" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073170", "target": "reaction_10073175" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073166", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073166", "target": "species_10073163" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073161", "target": "reaction_10073166" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073182", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073182", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073179", "target": "reaction_10073182" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073184", "target": "species_10073179" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073028", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073028", "target": "species_10065243" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073023", "target": "reaction_10073028" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10073026", "target": "reaction_10073028" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073031", "target": "species_10073023" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073175", "target": "species_10073172" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073175", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073172", "target": "reaction_10087367" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087367", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087367", "target": "species_10039728" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072939", "target": "species_10043237" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072939", "target": "species_10065241" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072924", "target": "reaction_10072939" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072927", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072927", "target": "species_10072924" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072922", "target": "reaction_10072927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072933", "target": "species_10072922" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073246", "target": "species_10073217" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073186", "target": "reaction_10073246" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073217", "target": "reaction_10073222" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073222", "target": "species_10073219" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040776", "target": "species_10036502" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040776", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040767", "target": "reaction_10040776" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040769", "target": "species_10040767" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036500", "target": "reaction_10040769" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040763", "target": "reaction_10040769" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040763", "target": "reaction_10057704" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057704", "target": "species_10057702" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036498", "target": "reaction_10057704" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036506", "target": "reaction_10057704" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057702", "target": "reaction_10057707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057707", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057707", "target": "species_10036508" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040720", "target": "species_10040718" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036438", "target": "reaction_10040720" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040706", "target": "reaction_10040720" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040718", "target": "reaction_10040788" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040788", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040788", "target": "species_10036459" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040744", "target": "species_10040734" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036405", "target": "reaction_10040744" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040722", "target": "reaction_10040744" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040734", "target": "reaction_10040785" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040742", "target": "reaction_10040744" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MZ06", "target": "species_10040742" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044642", "target": "Q9MZ06" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044642", "target": "species_10040740" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040785", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040785", "target": "species_10036432" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073328", "target": "species_10040742" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040740", "target": "reaction_10073328" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040736", "target": "reaction_10073328" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072909", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072909", "target": "species_10072906" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072904", "target": "reaction_10072909" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072906", "target": "reaction_10072929" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072929", "target": "species_10065255" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072929", "target": "species_10043237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065255", "target": "reaction_10072931" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065255", "target": "reaction_10072999" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065255", "target": "reaction_10072979" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072931", "target": "species_10072904" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073001", "target": "species_10072990" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072988", "target": "reaction_10073001" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072990", "target": "reaction_10072993" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073004", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073004", "target": "species_10072988" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072997", "target": "reaction_10073004" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072993", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072993", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072999", "target": "species_10072997" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073129", "target": "species_10073124" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065257", "target": "reaction_10073129" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065257", "target": "reaction_10073133" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073124", "target": "reaction_10073127" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087370", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087370", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065259", "target": "reaction_10087370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065259", "target": "reaction_10073242" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073133", "target": "species_10073131" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073131", "target": "reaction_10073136" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072976", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072976", "target": "species_10065257" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072961", "target": "reaction_10072976" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10072974", "target": "reaction_10072976" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073136", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073136", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072979", "target": "species_10072961" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073127", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073127", "target": "species_10065259" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073231", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073231", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065263", "target": "reaction_10073231" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073208", "target": "species_10073205" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073203", "target": "reaction_10073208" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073242", "target": "species_10073203" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073071", "target": "species_10073069" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073053", "target": "reaction_10073071" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073053", "target": "reaction_10073077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQI5", "target": "species_10073053" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQI5", "target": "species_10073069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQI5", "target": "species_10073075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039444", "target": "F1MQI5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073067", "target": "reaction_10073071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP99", "target": "species_10073067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP99", "target": "species_10073069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068413", "target": "A0A3Q1MP99" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH60", "target": "species_10073067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH60", "target": "species_10073069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046117", "target": "F1MH60" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073077", "target": "species_10073075" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073073", "target": "reaction_10073077" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073199", "target": "species_10073196" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073194", "target": "reaction_10073199" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073201", "target": "species_10073194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065249", "target": "reaction_10073201" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040794", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040794", "target": "species_10036379" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040702", "target": "reaction_10040794" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040704", "target": "species_10040702" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036375", "target": "reaction_10040704" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040698", "target": "reaction_10040704" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040698", "target": "reaction_10040773" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040696", "target": "species_10040694" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040690", "target": "reaction_10040696" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036328", "target": "reaction_10040696" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040694", "target": "reaction_10040791" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040791", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040791", "target": "species_10036344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040860", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040860", "target": "species_10036399" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040771", "target": "reaction_10040860" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040773", "target": "species_10040771" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036397", "target": "reaction_10040773" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073097", "target": "species_10072950" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073097", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073094", "target": "reaction_10073097" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073113", "target": "species_10073110" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073113", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073104", "target": "reaction_10073113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073110", "target": "reaction_10087373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073083", "target": "species_10073079" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065233", "target": "reaction_10073083" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065233", "target": "reaction_10073087" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065233", "target": "reaction_10073326" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065233", "target": "reaction_10072937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073079", "target": "reaction_10073090" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072957", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072957", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072954", "target": "reaction_10072957" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087373", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087373", "target": "species_10039728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073090", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073090", "target": "species_10065235" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073106", "target": "species_10073104" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072952", "target": "reaction_10073106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072952", "target": "reaction_10073108" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073108", "target": "species_10072954" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073225", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073225", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065239", "target": "reaction_10073225" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073115", "target": "species_10065253" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065251", "target": "reaction_10073115" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065253", "target": "reaction_10073228" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073228", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073228", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073087", "target": "species_10073085" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073085", "target": "reaction_10073102" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073119", "target": "species_10073117" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073099", "target": "reaction_10073119" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073117", "target": "reaction_10073122" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073102", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073102", "target": "species_10073099" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073122", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073122", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073326", "target": "species_10073324" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073322", "target": "reaction_10073326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R7", "target": "species_10073322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0R7", "target": "species_10073324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004298", "target": "F1N0R7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY74", "target": "species_10073322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY74", "target": "species_10073324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065908", "target": "G3MY74" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVT1", "target": "species_10073322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVT1", "target": "species_10073324" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028517", "target": "F1MVT1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072937", "target": "species_10072915" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072915", "target": "reaction_10072920" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072920", "target": "species_10072917" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072920", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072917", "target": "reaction_10072935" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072935", "target": "species_10043237" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072935", "target": "species_10065233" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091689", "target": "species_10091687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9674079", "target": "reaction_10091689" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040472", "target": "reaction_10091689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME99", "target": "species_10040472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME99", "target": "species_10091687" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067659", "target": "A0A3Q1ME99" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3Z8", "target": "species_10040472" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3Z8", "target": "species_10091687" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086976", "target": "A0A3Q1N3Z8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046666", "target": "species_10046664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046658", "target": "reaction_10046666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJY4", "target": "species_10046658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJY4", "target": "species_10046664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJY4", "target": "species_10046670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJY4", "target": "species_10046654" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061070", "target": "E1BJY4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061070", "target": "species_10046672" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046664", "target": "reaction_10046677" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10046677", "target": "species_10046672" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046677", "target": "species_10046670" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046674", "target": "reaction_10046677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10046674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIF6", "target": "species_10038305" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001642", "target": "A0A452DIF6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001642", "target": "species_10038265" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046660", "target": "species_10046658" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046654", "target": "reaction_10046660" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057850", "target": "species_10057847" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057850", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043813", "target": "reaction_10057850" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057854", "target": "species_10057852" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057840", "target": "reaction_10057854" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057852", "target": "reaction_10058474" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057872", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057872", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057869", "target": "reaction_10057872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058480", "target": "species_10057840" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058480", "target": "species_10052345" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058476", "target": "reaction_10058480" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091667", "target": "species_10091665" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043782", "target": "reaction_10091667" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043782", "target": "reaction_10091751" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9669722", "target": "reaction_10091667" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057845", "target": "species_10043809" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043807", "target": "reaction_10057845" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043809", "target": "reaction_10043815" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043832", "target": "species_10043830" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043828", "target": "reaction_10043832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10043828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10043830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10057864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10043826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10055926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH8", "target": "species_10055931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012781", "target": "F1MRH8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057867", "target": "species_10043826" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057867", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057864", "target": "reaction_10057867" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058474", "target": "species_10058471" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058474", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058471", "target": "reaction_10058478" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058478", "target": "species_10058476" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057857", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057857", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043817", "target": "reaction_10057857" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043815", "target": "species_10043813" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043811", "target": "reaction_10043815" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043811", "target": "reaction_10084309" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091751", "target": "species_10091749" }, { "type": "reactant", "sub_type": "other", "source": "species_9674322", "target": "reaction_10091751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057862", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057862", "target": "species_10043807" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057859", "target": "reaction_10057862" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041657", "target": "species_10041655" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041653", "target": "reaction_10041657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026471", "target": "species_10041653" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026471", "target": "E1BMX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10041655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMX5", "target": "species_10047732" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041649", "target": "species_10041443" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041441", "target": "reaction_10041649" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070651", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070651", "target": "species_10070649" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070647", "target": "reaction_10070651" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070580", "target": "reaction_10070651" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070580", "target": "reaction_10070589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLY9", "target": "species_10070580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLY9", "target": "species_10070586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLY9", "target": "species_10070591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLY9", "target": "species_10070578" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034285", "target": "E1BLY9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070589", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070589", "target": "species_10070586" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070657", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070657", "target": "species_10070605" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070655", "target": "reaction_10070657" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070628", "target": "species_10070626" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070612", "target": "reaction_10070628" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070615", "target": "species_10070612" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070615", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069535", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069535", "target": "species_10069532" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069530", "target": "reaction_10069535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10069530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10069532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10071501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10070638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z041", "target": "species_10070640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046702", "target": "A7Z041" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069532", "target": "reaction_10071506" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071504", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071504", "target": "species_10070638" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071501", "target": "reaction_10071504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRN2", "target": "species_10071501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRN2", "target": "species_10070638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRN2", "target": "species_10070642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRN2", "target": "species_10070640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075025", "target": "A0A3Q1MRN2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075025", "target": "species_10071499" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070638", "target": "reaction_10071508" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071506", "target": "species_10071501" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071499", "target": "reaction_10071506" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070645", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070645", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070642", "target": "reaction_10070645" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071508", "target": "species_10070640" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070676", "target": "species_10070674" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047604", "target": "reaction_10070676" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070672", "target": "reaction_10070676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZB2", "target": "species_10070672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZB2", "target": "species_10070674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZB2", "target": "species_10070619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZB2", "target": "species_10070621" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024518", "target": "Q1LZB2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070624", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070624", "target": "species_10070621" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070619", "target": "reaction_10070624" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070594", "target": "species_10070578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070594", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070591", "target": "reaction_10070594" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070578", "target": "reaction_10070596" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070596", "target": "species_10070580" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056781", "target": "species_10056779" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056771", "target": "reaction_10056781" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056765", "target": "reaction_10056781" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056779", "target": "reaction_10057151" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057151", "target": "species_10057149" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057149", "target": "reaction_10057166" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057166", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057166", "target": "species_10057163" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057184", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057184", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057181", "target": "reaction_10057184" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090971", "target": "species_10057250" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057248", "target": "reaction_10090971" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10057248", "target": "reaction_10086589" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057248", "target": "reaction_10086581" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057211", "target": "reaction_10090971" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057211", "target": "reaction_10057272" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057211", "target": "reaction_10057298" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057211", "target": "reaction_10057252" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057211", "target": "reaction_10057286" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10057250", "target": "reaction_10057252" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057262", "target": "species_10057259" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057257", "target": "reaction_10057262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PG0", "target": "species_10057257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PG0", "target": "species_10057259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020867", "target": "Q32PG0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020867", "target": "species_10055126" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057264", "target": "species_10057257" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055126", "target": "reaction_10057264" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057255", "target": "reaction_10057264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057272", "target": "species_10057270" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057268", "target": "reaction_10057272" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057268", "target": "reaction_10084909" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086215", "target": "species_10057268" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086215", "target": "A0A3Q1LVN4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVN4", "target": "species_10057270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVN4", "target": "species_10084907" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057298", "target": "species_10057296" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057236", "target": "species_10057211" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057201", "target": "reaction_10057236" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057233", "target": "reaction_10057236" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057233", "target": "reaction_10069285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNM1", "target": "species_10057233" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068424", "target": "A0A3Q1LNM1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH7", "target": "species_10057233" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086383", "target": "A0A3Q1MBH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDC6", "target": "species_10057233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDC6", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDC6", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075241", "target": "A0A3Q1MDC6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5G235", "target": "species_10057233" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024745", "target": "Q5G235" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057252", "target": "species_10057246" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057284", "target": "species_10057282" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057278", "target": "reaction_10057284" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057286", "target": "species_10057278" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084080", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084080", "target": "species_10084077" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084065", "target": "reaction_10084080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ6", "target": "species_10084065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ6", "target": "species_10084077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ6", "target": "species_10080868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ6", "target": "species_10080866" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020028", "target": "E1BCZ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDW7", "target": "species_10084065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDW7", "target": "species_10084077" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDW7", "target": "species_10080868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDW7", "target": "species_10080858" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030663", "target": "E1BDW7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084067", "target": "species_10084065" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080868", "target": "reaction_10084067" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080866", "target": "reaction_10084067" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080866", "target": "reaction_10080870" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080870", "target": "species_10080868" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080858", "target": "reaction_10080870" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091705", "target": "species_10091703" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091695", "target": "reaction_10091705" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091695", "target": "reaction_10091701" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005126", "target": "species_10091695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005126", "target": "Q3SZK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK1", "target": "species_10091703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZK1", "target": "species_10091699" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040393", "target": "species_10040388" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040366", "target": "reaction_10040393" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040366", "target": "reaction_10040462" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040458", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040458", "target": "species_10040395" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040455", "target": "reaction_10040458" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040395", "target": "reaction_10040432" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040395", "target": "reaction_10040421" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040460", "target": "species_10040455" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040449", "target": "reaction_10040460" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040447", "target": "species_10040444" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040440", "target": "reaction_10040447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ1", "target": "species_10040440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ1", "target": "species_10040444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ1", "target": "species_10040382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ1", "target": "species_10040384" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028307", "target": "A6QLQ1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040462", "target": "species_10040444" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040382", "target": "reaction_10040462" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040369", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040369", "target": "species_10040366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040361", "target": "reaction_10040369" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040432", "target": "species_10040425" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10040430", "target": "reaction_10040432" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061187", "target": "species_10040430" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040451", "target": "species_10040449" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040386", "target": "species_10040384" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040374", "target": "reaction_10040386" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040453", "target": "species_10040361" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040421", "target": "species_10040419" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040417", "target": "reaction_10040421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DX1", "target": "species_10040417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DX1", "target": "species_10040419" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018755", "target": "Q08DX1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M839", "target": "species_10040417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M839", "target": "species_10040419" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073657", "target": "A0A3Q1M839" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040331", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040331", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040301", "target": "reaction_10040331" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040303", "target": "species_10040301" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040283", "target": "reaction_10040303" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040286", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040286", "target": "species_10040283" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040256", "target": "reaction_10040286" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040258", "target": "species_10040256" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040289", "target": "species_10040243" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040289", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040227", "target": "reaction_10040289" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040227", "target": "reaction_10040310" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036616", "target": "species_10035491" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035489", "target": "reaction_10036616" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035489", "target": "reaction_10090916" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035489", "target": "reaction_10047455" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040317", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040317", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040314", "target": "reaction_10040317" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040326", "target": "species_10040314" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040323", "target": "species_10040225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040223", "target": "reaction_10040323" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040225", "target": "reaction_10040229" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10040321", "target": "reaction_10040323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030750", "target": "species_10040321" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040229", "target": "species_10040227" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044472", "target": "species_10043237" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044472", "target": "species_10040243" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044467", "target": "reaction_10044472" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044465", "target": "species_10044463" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043197", "target": "reaction_10044465" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043197", "target": "reaction_10084153" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043197", "target": "reaction_10044024" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044463", "target": "reaction_10044470" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044470", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044470", "target": "species_10044467" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040310", "target": "species_10040243" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040310", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035536", "target": "species_10035534" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035532", "target": "reaction_10035536" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075065", "target": "species_10036624" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075065", "target": "species_10035532" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036626", "target": "reaction_10075065" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075097", "target": "species_10036624" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075097", "target": "species_10035503" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036628", "target": "reaction_10075097" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083487", "target": "species_10083485" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083565", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083565", "target": "species_10083562" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083565", "target": "species_10083480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083556", "target": "reaction_10083565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10083556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10083562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10083554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10089607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10040351" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10040353" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10087383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10056599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10087392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10087465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10087491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10087501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10035737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KY4", "target": "species_10035743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079975", "target": "Q32KY4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10083556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10083562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10083554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10089607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10088001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10088003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087381" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10056599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10087501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10035737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIV3", "target": "species_10035743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023277", "target": "A0A452DIV3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023277", "target": "species_10056568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023277", "target": "species_10035731" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023277", "target": "species_10035739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10083556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10083562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10083554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10056599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10087392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10087465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10087491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10087501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS3", "target": "species_10087390" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083558", "target": "species_10083556" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083554", "target": "reaction_10083558" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083646", "target": "species_10083644" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083642", "target": "reaction_10083646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079568", "target": "species_10083642" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079568", "target": "A0A3Q1M4A0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079568", "target": "species_10083649" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083644", "target": "reaction_10083652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4A0", "target": "species_10083644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083632", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083632", "target": "species_10052267" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083652", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083652", "target": "species_10083649" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083652", "target": "species_10083480" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083638", "target": "species_10083635" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083690", "target": "species_10083687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083690", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083690", "target": "species_10083480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083682", "target": "reaction_10083690" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083687", "target": "reaction_10083697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083581", "target": "species_10083579" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070667", "target": "reaction_10083581" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024101", "target": "species_10070667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024101", "target": "F1MFD1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024101", "target": "species_10083585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024101", "target": "species_10049875" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083579", "target": "reaction_10083588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFD1", "target": "species_10083579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFD1", "target": "species_10049881" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083629", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083629", "target": "species_10083626" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083629", "target": "species_10083480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083620", "target": "reaction_10083629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ07", "target": "species_10083620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073322", "target": "A0A3Q1MQ07" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073322", "target": "species_10083626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073322", "target": "species_10083618" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083695", "target": "species_10083687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083695", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083695", "target": "species_10037313" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083692", "target": "reaction_10083695" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083697", "target": "species_10083692" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083588", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083588", "target": "species_10083585" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083588", "target": "species_10083480" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083684", "target": "species_10083682" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083680", "target": "reaction_10083684" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083622", "target": "species_10083620" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083618", "target": "reaction_10083622" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083707", "target": "species_10083700" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083707", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083704", "target": "reaction_10083707" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002574", "target": "species_10083704" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083726", "target": "species_10083724" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055952", "target": "reaction_10083726" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10055952", "target": "reaction_10055955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008678", "target": "species_10055952" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008678", "target": "A6QQN2" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083724", "target": "reaction_10083729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQN2", "target": "species_10083724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQN2", "target": "species_10056255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQN2", "target": "species_10056265" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083729", "target": "species_29372" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083729", "target": "species_10055952" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083729", "target": "species_10083473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090428", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090428", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090425", "target": "reaction_10090428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEQ7", "target": "species_10090425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEQ7", "target": "species_10089837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEQ7", "target": "species_10089839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEQ7", "target": "species_10090415" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010781", "target": "F1MEQ7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089841", "target": "species_10089839" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047493", "target": "reaction_10089841" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047493", "target": "reaction_10049395" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089837", "target": "reaction_10089841" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090501", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090501", "target": "species_10089837" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090415", "target": "reaction_10090501" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073851", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073851", "target": "species_10073848" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039143", "target": "reaction_10073851" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039143", "target": "reaction_10039180" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039143", "target": "reaction_10039155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N197", "target": "species_10039143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N197", "target": "species_10073848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N197", "target": "species_10039147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N197", "target": "species_10039141" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007575", "target": "F1N197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007575", "target": "species_10039145" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046572", "target": "species_10046570" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042890", "target": "reaction_10046572" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042890", "target": "reaction_10046583" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046588", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046588", "target": "species_10046585" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046583", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046583", "target": "species_10042880" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10046580", "target": "reaction_10046583" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024128", "target": "species_10046580" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049894", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049894", "target": "species_10039178" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10039178", "target": "reaction_10039180" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088493", "target": "species_10039121" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039075", "target": "reaction_10088493" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039119", "target": "reaction_10088493" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039121", "target": "reaction_10088496" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073853", "target": "species_10039147" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039145", "target": "reaction_10073853" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10039147", "target": "reaction_10039155" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088496", "target": "species_29468" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428011", "target": "reaction_10088496" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039059", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039059", "target": "species_10039057" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039055", "target": "reaction_10039059" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039057", "target": "reaction_10039127" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039057", "target": "reaction_10091404" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039209", "target": "species_10039207" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039209", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039204", "target": "reaction_10039209" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023487", "target": "species_10039204" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023487", "target": "species_10039207" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039168", "target": "reaction_10039209" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039168", "target": "reaction_10039200" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022415", "target": "species_10039168" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022415", "target": "species_10039164" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039160", "target": "species_10034357" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039160", "target": "species_10039131" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039133", "target": "reaction_10039160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A7", "target": "species_10039133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A7", "target": "species_10034363" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039828", "target": "Q0P5A7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039828", "target": "species_10039131" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039828", "target": "species_10034361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEI6", "target": "species_10039133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEI6", "target": "species_10034363" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEI6", "target": "species_10060726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEI6", "target": "species_10060724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068997", "target": "A0A3Q1NEI6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068997", "target": "species_10034357" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091741", "target": "species_10039153" }, { "type": "reactant", "sub_type": "other", "source": "species_9678687", "target": "reaction_10091741" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039151", "target": "reaction_10091741" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039151", "target": "reaction_10091817" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010928", "target": "species_10039151" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010928", "target": "P18203" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10039153", "target": "reaction_10039180" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10039153", "target": "reaction_10039155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18203", "target": "species_10039153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18203", "target": "species_10091815" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039180", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039180", "target": "species_10039168" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039164", "target": "reaction_10039180" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039200", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039200", "target": "species_10039197" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034529", "target": "reaction_10039200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10034529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10039197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N412", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019214", "target": "A0A3Q1N412" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019214", "target": "E1B8K9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10034529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10039197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8K9", "target": "species_10053041" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039155", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039155", "target": "species_10039133" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034363", "target": "reaction_10039155" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034363", "target": "reaction_10034365" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072900", "target": "species_10039117" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039101", "target": "reaction_10072900" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039115", "target": "reaction_10072900" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039117", "target": "reaction_10072902" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073844", "target": "species_10039143" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039141", "target": "reaction_10073844" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037666", "target": "reaction_10073844" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037666", "target": "reaction_10051066" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037666", "target": "reaction_10050318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039127", "target": "species_10039125" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039123", "target": "reaction_10039127" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072902", "target": "species_10039119" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039095", "target": "reaction_10072902" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046602", "target": "species_10046599" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046602", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046594", "target": "reaction_10046602" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM00", "target": "species_10046594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM00", "target": "species_10046599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022347", "target": "F1MM00" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022347", "target": "species_10046592" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046604", "target": "species_10046594" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046592", "target": "reaction_10046604" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085865", "target": "species_10085863" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085861", "target": "reaction_10085865" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065187", "target": "species_10085861" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065187", "target": "E1BPS0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085857", "target": "reaction_10085865" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015193", "target": "species_10085857" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015193", "target": "Q8SQ19" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQ19", "target": "species_10085863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPS0", "target": "species_10085863" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060285", "target": "species_2104997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060285", "target": "species_1606845" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2105007", "target": "reaction_10060285" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060282", "target": "reaction_10060285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU84", "target": "species_10060282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU84", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU84", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006001", "target": "F1MU84" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091293", "target": "species_2105010" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091293", "target": "species_1605658" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2105012", "target": "reaction_10091293" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2105012", "target": "reaction_10060295" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059946", "target": "reaction_10091293" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059946", "target": "reaction_10091289" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059946", "target": "reaction_10091291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWW2", "target": "species_10059946" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWW2", "target": "species_10059941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWW2", "target": "species_10059948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWW2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWW2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048411", "target": "H7BWW2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060293", "target": "species_1606845" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060293", "target": "species_2105012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2104995", "target": "reaction_10060293" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060290", "target": "reaction_10060293" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023218", "target": "species_10060290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023218", "target": "F1MXZ0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060295", "target": "species_2105010" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060295", "target": "species_1605658" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059941", "target": "reaction_10060295" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059941", "target": "reaction_10059944" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059941", "target": "reaction_10063807" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059941", "target": "reaction_10064593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0V8R6", "target": "species_10059941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0V8R6", "target": "species_10059948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017261", "target": "Q0V8R6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063510", "target": "species_10060854" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063483", "target": "reaction_10063510" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063483" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10060854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063230" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063240" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05443", "target": "species_10063464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002279", "target": "Q05443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063483" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10060854" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063230" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063240" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13605", "target": "species_10063464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019854", "target": "P13605" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038201", "target": "species_10038198" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038201", "target": "species_10038196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038201", "target": "species_10038188" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038157", "target": "reaction_10038201" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0B6", "target": "species_10038157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0B6", "target": "species_10038196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0B6", "target": "species_10038143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0B6", "target": "species_10038145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0B6", "target": "species_10038147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013734", "target": "Q3T0B6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038188", "target": "reaction_10038213" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091546", "target": "species_10038209" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091544", "target": "reaction_10091546" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038209", "target": "reaction_10038213" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038209", "target": "reaction_10084020" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038205", "target": "species_10038145" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038143", "target": "reaction_10038205" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038203", "target": "reaction_10038205" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038145", "target": "reaction_10038149" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090718", "target": "species_10038217" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9603327", "target": "reaction_10090718" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038129", "target": "species_10038127" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037535", "target": "reaction_10038129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1G4", "target": "species_10037535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1G4", "target": "species_10038127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1G4", "target": "species_10038182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019525", "target": "F1N1G4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG29", "target": "species_10037535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG29", "target": "species_10038127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG29", "target": "species_10038182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017571", "target": "E1BG29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B863", "target": "species_10037535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B863", "target": "species_10038127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B863", "target": "species_10038182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055945", "target": "E1B863" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038121", "target": "reaction_10038129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT55", "target": "species_10038121" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT55", "target": "species_10038127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT55", "target": "species_10038182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087456", "target": "A0A3Q1LT55" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038127", "target": "reaction_10038221" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091600", "target": "species_10038115" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076686", "target": "reaction_10091600" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091671", "target": "species_10091669" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091671", "target": "species_10071930" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071934", "target": "reaction_10091671" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071934", "target": "reaction_10071946" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038166", "target": "species_10038157" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038147", "target": "reaction_10038166" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038163", "target": "reaction_10038166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAU4", "target": "species_10038163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAU4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAU4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAU4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAU4", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047906", "target": "F1MAU4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090185", "target": "species_10038215" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9603311", "target": "reaction_10090185" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071946", "target": "species_10038174" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038221", "target": "species_10038182" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037829", "target": "reaction_10038221" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037829", "target": "reaction_10037845" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037843", "target": "reaction_10038221" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037843", "target": "reaction_10037845" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18085", "target": "species_10037843" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18085", "target": "species_10037841" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZY1", "target": "species_10037843" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZY1", "target": "species_10037841" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011485", "target": "Q8HZY1" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10038219", "target": "reaction_10038221" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038149", "target": "species_10038147" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038133", "target": "reaction_10038149" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038213", "target": "species_10038211" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035301", "target": "species_10035299" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035297", "target": "reaction_10035301" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006308", "target": "species_10035297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006308", "target": "E1B883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035293", "target": "reaction_10035301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMP0", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMP0", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMP0", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045075", "target": "Q1RMP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10037169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P78", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043971", "target": "Q32P78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ29", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ29", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ29", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016250", "target": "Q3SZ29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWA1", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWA1", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWA1", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047621", "target": "A7YWA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIX2", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIX2", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIX2", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008496", "target": "E1BIX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10037169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBC0", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030510", "target": "Q3ZBC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QVL1", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QVL1", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QVL1", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032261", "target": "F6QVL1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS0", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS0", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS0", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018830", "target": "A6QLS0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L22", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L22", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L22", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025246", "target": "Q32L22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10035293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10035299" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10037169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4H3", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000606", "target": "F2Z4H3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B883", "target": "species_10035299" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035254", "target": "species_10035053" }, { "type": "reactant", "sub_type": "", "source": "species_73682", "target": "reaction_10035254" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035051", "target": "reaction_10035254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034806", "target": "species_10035051" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034806", "target": "F1MCZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCZ7", "target": "species_10035053" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035231", "target": "reaction_10035254" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035231", "target": "reaction_10071065" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035252", "target": "reaction_10035254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E683", "target": "species_10035252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053498", "target": "G5E683" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053498", "target": "species_10035235" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034224", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034221", "target": "reaction_10034224" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P37980", "target": "species_10034221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010311", "target": "P37980" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050169", "target": "species_113548" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159450", "target": "reaction_10050169" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050166", "target": "reaction_10050169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXA8", "target": "species_10050166" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086411", "target": "A0A3Q1LXA8" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_109496", "target": "reaction_10050169" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038107", "target": "species_10038105" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038103", "target": "reaction_10038107" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005581", "target": "species_10038103" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005581", "target": "Q3SYU2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005581", "target": "species_10071569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005581", "target": "species_10071572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005581", "target": "species_10071559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU2", "target": "species_10038105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU2", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU2", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU2", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU2", "target": "species_10081263" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038082", "target": "species_10038080" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038082", "target": "species_10034641" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034837", "target": "reaction_10038082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJF6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055065", "target": "A0A452DJF6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSI3", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020266", "target": "Q9XSI3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q861S4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002160", "target": "Q861S4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR67", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071569", "target": "A0A3Q1LR67" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T003", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021033", "target": "Q3T003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII3", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037203", "target": "E1BII3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61257", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016378", "target": "P61257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T057", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004190", "target": "Q3T057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61356", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023183", "target": "P61356" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q862I1", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017905", "target": "Q862I1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P39872", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004188", "target": "P39872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DT1", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026826", "target": "Q58DT1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIZ2", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027850", "target": "A0A452DIZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DQ3", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033359", "target": "Q58DQ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025963", "target": "Q5E9E6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0S6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037367", "target": "Q3T0S6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4M0", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036905", "target": "A0A3Q1M4M0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBQ5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015358", "target": "Q2TBQ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61284", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009155", "target": "P61284" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G8JKV5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084955", "target": "G8JKV5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYR7", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019298", "target": "Q3SYR7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LH67", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035330", "target": "A0A3Q1LH67" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035330", "target": "species_10034641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST0", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020729", "target": "A0A3Q1LST0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020729", "target": "Q5EAD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD6", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T171", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075433", "target": "Q3T171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHM9", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015544", "target": "E1BHM9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MIC0", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071825", "target": "Q3MIC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79244", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006781", "target": "P79244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW0", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006866", "target": "Q58DW0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDN4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055086", "target": "F1MDN4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB9", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042547", "target": "Q32PB9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002626", "target": "Q58DW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42899", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002326", "target": "P42899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K14", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024376", "target": "Q56K14" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ34", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031754", "target": "A0A452DJ34" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56K03", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066379", "target": "Q56K03" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG09", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050149", "target": "F1MG09" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050149", "target": "Q3SZ59" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ59", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0D5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069699", "target": "Q3T0D5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW3", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024788", "target": "Q58DW3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZQ6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020323", "target": "Q3SZQ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T051", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087168", "target": "Q3T051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM7", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004161", "target": "Q3MHM7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10034837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10038080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML72", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071912", "target": "F1ML72" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10034365", "target": "species_10034357" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10034365", "target": "species_10034361" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10034855", "target": "species_10034853" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034855", "target": "species_10034837" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034855", "target": "species_10034609" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034839", "target": "reaction_10034855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0F4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020719", "target": "Q3T0F4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PD5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032643", "target": "Q32PD5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032643", "target": "E1BHA5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHA5", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018491", "target": "Q3T0V4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q76I82", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069480", "target": "Q76I82" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LLI8", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072836", "target": "A0A3Q1LLI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JV9", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013079", "target": "Q56JV9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0X6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028093", "target": "Q3T0X6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62276", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077396", "target": "P62276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T169", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003962", "target": "Q3T169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH1", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084646", "target": "A0A3Q1MFH1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085499", "target": "A0A3Q1LRX4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085499", "target": "A0A3Q1MIM5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIM5", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003201", "target": "Q56JX6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JU9", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073736", "target": "Q56JU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR01", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075650", "target": "F1MR01" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075650", "target": "A0A3Q1LNR2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNR2", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040046", "target": "Q56JX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT7", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018414", "target": "Q2KHT7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JX8", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055693", "target": "Q56JX8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5N2", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085238", "target": "A0A3Q1M5N2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEQ3", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063143", "target": "E1BEQ3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063143", "target": "Q3T199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T199", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PB8", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027713", "target": "Q32PB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K1", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082341", "target": "A0A3Q1M9K1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082341", "target": "A0A3Q1LNI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNI8", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080007", "target": "E1B7E5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080007", "target": "A0A3Q1LNV2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080007", "target": "A0A3Q1MSH8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCB7", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025298", "target": "E1BCB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV2", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSH8", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE06", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "A2VE06" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "G3N267" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "E1BGR7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "F1MJH2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "A0A3Q1LQD0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063866", "target": "G3N0K3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N267", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGR7", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJH2", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79103", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025024", "target": "P79103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD0", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0K3", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBL4", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020462", "target": "A0A3Q1MBL4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10034839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10034609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10060890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH8", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025484", "target": "Q3ZBH8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10034853", "target": "reaction_10034855" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023455", "target": "species_10034853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023455", "target": "Q32LC3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034905", "target": "species_10034903" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034901", "target": "reaction_10034905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7R4", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7R4", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061515", "target": "E1B7R4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ8", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ8", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049219", "target": "E1BLZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB16", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB16", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084055", "target": "A7MB16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V3", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0V3", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014888", "target": "Q3T0V3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E966", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E966", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077067", "target": "Q5E966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCK1", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCK1", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014281", "target": "Q3ZCK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T122", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T122", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037985", "target": "Q3T122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW6", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYW6", "target": "species_10034903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023384", "target": "Q3SYW6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LC3", "target": "species_10034901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LC3", "target": "species_10034903" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034385", "target": "reaction_10034905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU8", "target": "species_10034385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU8", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU8", "target": "species_10034379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU8", "target": "species_10034381" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU8", "target": "species_10070741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019064", "target": "Q2KHU8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68102", "target": "species_10034385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68102", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68102", "target": "species_10034379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68102", "target": "species_10034381" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68102", "target": "species_10070741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071779", "target": "P68102" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQI5", "target": "species_10034385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQI5", "target": "species_10034903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQI5", "target": "species_10034379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQI5", "target": "species_10034381" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQI5", "target": "species_10070741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086329", "target": "A0A3Q1LQI5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034383", "target": "species_10034381" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034379", "target": "reaction_10034383" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034379", "target": "reaction_10070743" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034381", "target": "reaction_10034387" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034387", "target": "species_10034385" }, { "type": "reactant", "sub_type": "", "source": "species_72393", "target": "reaction_10034387" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060894", "target": "species_10060892" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060890", "target": "reaction_10060894" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060888", "target": "reaction_10060894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9U1", "target": "species_10060888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9U1", "target": "species_10060892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025405", "target": "Q2T9U1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB38", "target": "species_10060888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB38", "target": "species_10060892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014015", "target": "E1BB38" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10060888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10060892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQL9", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019085", "target": "A6QQL9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYQ7", "target": "species_10060888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYQ7", "target": "species_10060892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076619", "target": "A0A3Q1LYQ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG7", "target": "species_10060888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG7", "target": "species_10060892" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017007", "target": "Q3ZBG7" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048380", "target": "species_10048378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048376", "target": "reaction_10048380" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10046723", "target": "species_10046626" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046709", "target": "reaction_10046723" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046721", "target": "reaction_10046723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Q3", "target": "species_10046721" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026313", "target": "E1B8Q3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGS8", "target": "species_10046721" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGS8", "target": "species_10083225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGS8", "target": "species_10083229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGS8", "target": "species_10083806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082648", "target": "A0A3Q1NGS8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046717", "target": "reaction_10046723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5H9", "target": "species_10046717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019647", "target": "G5E5H9" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:71466", "target": "species_10046717" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:71466", "target": "species_6803725" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046130", "target": "reaction_10046723" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10046723" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10048429" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10049053" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10089038" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10089024" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10085907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70115", "target": "reaction_10089029" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045736", "target": "species_10045702" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045700", "target": "reaction_10045736" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014462", "target": "species_10045700" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014462", "target": "P04837" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041260", "target": "reaction_10045736" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041260", "target": "reaction_10045694" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041260", "target": "reaction_10045744" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041260", "target": "reaction_10045696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04837", "target": "species_10045702" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045734", "target": "reaction_10045736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7M7", "target": "species_10045734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7M7", "target": "species_10045722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025401", "target": "E1B7M7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFT5", "target": "species_10045734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFT5", "target": "species_10045722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008663", "target": "E1BFT5" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10045722", "target": "reaction_10045736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07994", "target": "species_10045722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013154", "target": "P07994" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045694", "target": "species_10043954" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043952", "target": "reaction_10045694" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043954", "target": "reaction_10043980" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043954", "target": "reaction_10043956" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045744", "target": "species_10045742" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045740", "target": "reaction_10045744" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045696", "target": "species_10041267" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041265", "target": "reaction_10045696" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091056", "target": "species_8878776" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091056", "target": "species_9619021" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9619052", "target": "reaction_10091056" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076366", "target": "reaction_10091056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTP2", "target": "species_10076366" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTP2", "target": "species_10076372" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032461", "target": "F1MTP2" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048461", "target": "species_10048438" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048434", "target": "reaction_10048461" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048458", "target": "reaction_10048461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67810", "target": "species_10048458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014925", "target": "P67810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI36", "target": "species_10048458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015866", "target": "Q2KI36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLX7", "target": "species_10048458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083476", "target": "A0A3Q1MLX7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI2", "target": "species_10048458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008726", "target": "E1BEI2" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048429", "target": "species_10048423" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048429", "target": "species_10046085" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048421", "target": "reaction_10048429" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048413", "target": "reaction_10048429" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10048427", "target": "reaction_10048429" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048427", "target": "reaction_10054779" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082606", "target": "species_10048427" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082606", "target": "A0A3Q1LZG1" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_422024", "target": "reaction_10048429" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048465", "target": "species_10048463" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_422042", "target": "reaction_10048465" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048398", "target": "reaction_10048465" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048398", "target": "reaction_10048407" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048404", "target": "reaction_10048465" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048404", "target": "reaction_10048407" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000986", "target": "species_10048404" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10048407", "target": "species_10048400" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_422019", "target": "reaction_10048407" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049385", "target": "species_216785" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049382", "target": "reaction_10049385" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001343", "target": "species_10049382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049392", "target": "species_216785" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049389", "target": "reaction_10049392" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086579", "target": "species_10049389" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085101", "target": "species_10085076" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085101", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085101", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10085101" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10085250" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10091661" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10040842" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10055647" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040838", "target": "reaction_10084028" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085098", "target": "reaction_10085101" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2U5", "target": "species_10085098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064999", "target": "G3N2U5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E2Z5", "target": "species_10085098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017043", "target": "A7E2Z5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKB4", "target": "species_10085098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069658", "target": "E1BKB4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085250", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085250", "target": "species_10085237" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085250", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085247", "target": "reaction_10085250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N325", "target": "species_10085247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034047", "target": "F1N325" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S4", "target": "species_10085247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065735", "target": "G3N3S4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087993", "target": "species_10087990" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087993", "target": "species_10087869" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087978", "target": "reaction_10087993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10087850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10075937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10088774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10088785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10075933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ64", "target": "species_10076080" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028591", "target": "E1BJ64" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028591", "target": "species_10075935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028591", "target": "species_10075939" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028591", "target": "species_10075931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMW1", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMW1", "target": "species_10087871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMW1", "target": "species_10087880" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037020", "target": "Q1RMW1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037020", "target": "species_10087869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTL8", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTL8", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTL8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTL8", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087337", "target": "A0A3Q1MTL8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII4", "target": "species_10037199" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078734", "target": "Q2KII4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078734", "target": "species_10055146" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078734", "target": "species_10037193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXH0", "target": "species_10092091" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068692", "target": "A0A3Q1MXH0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068692", "target": "species_10055162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ32", "target": "species_10037199" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026036", "target": "Q3SZ32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026036", "target": "species_10055148" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026036", "target": "species_10037197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5F4", "target": "species_10092091" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002831", "target": "Q0P5F4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002831", "target": "species_10055212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ2", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024202", "target": "E1BHZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHZ2", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022024", "target": "Q3MHZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJT8", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070334", "target": "A0A3Q1MJT8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWW0", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011810", "target": "F1MWW0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5W3", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075739", "target": "A0A3Q1M5W3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ12", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025032", "target": "E1BJ12" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH7", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001270", "target": "F1MTH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N349", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002623", "target": "F1N349" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10088804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKN8", "target": "species_10092145" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023144", "target": "E1BKN8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023144", "target": "species_10087926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH6", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044628", "target": "A7MBH6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ71", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038842", "target": "A0A452DJ71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "H7BWV6", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009484", "target": "H7BWV6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ53", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030652", "target": "Q2HJ53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM1", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069213", "target": "E1BCM1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S2", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013884", "target": "E1B9S2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH6", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004378", "target": "E1BEH6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10087978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10087990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKE5", "target": "species_10088804" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064207", "target": "E1BKE5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087869", "target": "reaction_10087885" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087848", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087848", "target": "species_10087845" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087848", "target": "species_76577" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075935", "target": "reaction_10087848" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075935", "target": "reaction_10087852" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087835", "target": "reaction_10087848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJI4", "target": "species_10087835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJI4", "target": "species_10087845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJI4", "target": "species_10087871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJI4", "target": "species_10087850" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077128", "target": "A0A3Q1MJI4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X4", "target": "species_10087835" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X4", "target": "species_10087845" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X4", "target": "species_10087871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X4", "target": "species_10087850" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013367", "target": "E1B8X4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087845", "target": "reaction_10087852" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087883", "target": "species_10087845" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087883", "target": "species_10087880" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087871", "target": "reaction_10087883" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087885", "target": "species_10087871" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087850", "target": "reaction_10087885" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087852", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087852", "target": "species_10087850" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087852", "target": "species_76577" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088734", "target": "species_10088732" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088730", "target": "reaction_10088734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013112", "target": "species_10088730" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013112", "target": "A7MBJ5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013112", "target": "species_10076087" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088728", "target": "reaction_10088734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKZ4", "target": "species_10076067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072958", "target": "A0A3Q1LKZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNL1", "target": "species_10076067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086637", "target": "A0A3Q1MNL1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ09", "target": "species_10076067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028740", "target": "A0A452DJ09" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L87", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L87", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004550", "target": "Q32L87" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYV7", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYV7", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019879", "target": "F1MYV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVI8", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVI8", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028594", "target": "F1MVI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPL4", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPL4", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070605", "target": "A0A3Q1LPL4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXE6", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXE6", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015886", "target": "G3MXE6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMD0", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMD0", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010105", "target": "E1BMD0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY43", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY43", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086238", "target": "A0A3Q1MY43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT78", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT78", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084712", "target": "A0A3Q1LT78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9A9", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9A9", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022696", "target": "Q5E9A9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3H0", "target": "species_10088728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3H0", "target": "species_10088732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086437", "target": "F1N3H0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10088732" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBJ5", "target": "species_10076089" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087825", "target": "species_10075927" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087825", "target": "species_10075935" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075937", "target": "reaction_10087825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIW5", "target": "species_10075937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIW5", "target": "species_10075933" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079440", "target": "A0A3Q1MIW5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079440", "target": "species_10075927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088688", "target": "species_10088686" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076087", "target": "reaction_10088688" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076087", "target": "reaction_10076091" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088684", "target": "reaction_10088688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV4", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPV4", "target": "species_10088686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006480", "target": "A6QPV4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RM5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RM5", "target": "species_10088686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004519", "target": "Q29RM5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N162", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N162", "target": "species_10088686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011028", "target": "F1N162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB89", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB89", "target": "species_10088686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011464", "target": "A7MB89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L9", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073772", "target": "A0A3Q1N1L9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D00", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085937", "target": "Q58D00" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHW1", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003178", "target": "A0A452DHW1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN48", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078511", "target": "A0A3Q1MN48" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKK2", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052368", "target": "A5PKK2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK68", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016959", "target": "E1BK68" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PQR5", "target": "species_10084211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046646", "target": "F6PQR5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086266", "target": "A7MBH8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNU6", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085125", "target": "A0A3Q1LNU6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHT6", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021554", "target": "Q2KHT6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI01", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003249", "target": "A0A452DI01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1C5", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019285", "target": "F1N1C5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10084098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10084100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N019", "target": "species_10084203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004177", "target": "F1N019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004177", "target": "species_10054914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004177", "target": "species_10084209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDP9", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067912", "target": "A0A3Q1MDP9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW5", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083919", "target": "A0A3Q1MCW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQM8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080785", "target": "A0A3Q1LQM8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10077375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10077377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10086712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10086714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10040513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10040519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB09", "target": "species_10057814" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018036", "target": "A7MB09" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLW5", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080771", "target": "A0A3Q1MLW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP22", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025095", "target": "A6QP22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX0", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003665", "target": "A5PJX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q3", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001868", "target": "E1B9Q3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFJ4", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086616", "target": "A0A3Q1LFJ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC0", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012776", "target": "A0A452DIC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA7", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027498", "target": "F1MDA7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10056243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10071973" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M118", "target": "species_10066482" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075176", "target": "A0A3Q1M118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSC9", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082146", "target": "F1MSC9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M680", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080715", "target": "A0A3Q1M680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA2", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011600", "target": "A0A452DIA2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGE6", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050675", "target": "E1BGE6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QK6", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009501", "target": "Q17QK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10088684" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10088686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10088802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003367", "target": "F1MLX8" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088787", "target": "species_10088764" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088761", "target": "reaction_10088787" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018046", "target": "species_10088761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018046", "target": "species_10088764" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088774", "target": "reaction_10088787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM39", "target": "species_10088774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM39", "target": "species_10088785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026522", "target": "E1BM39" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10088785", "target": "reaction_10088787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R7X9", "target": "species_10088785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024194", "target": "F6R7X9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK00", "target": "species_10088785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061262", "target": "E1BK00" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088807", "target": "species_10088804" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088807", "target": "species_10075935" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088802", "target": "reaction_10088807" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084815", "target": "reaction_10088807" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084815", "target": "reaction_10084819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME43", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME43", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME43", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME43", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071522", "target": "A0A3Q1ME43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X736", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X736", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X736", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X736", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025677", "target": "G3X736" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QE33", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QE33", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QE33", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QE33", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014754", "target": "F6QE33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI56", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI56", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI56", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI56", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069661", "target": "Q2KI56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA0", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA0", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA0", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZA0", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009128", "target": "Q3SZA0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP8", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP8", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP8", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP8", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003609", "target": "F1MBP8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV74", "target": "species_10084815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV74", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV74", "target": "species_10076067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV74", "target": "species_10076065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007696", "target": "A4FV74" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075942", "target": "species_10075939" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075942", "target": "species_10075937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075933", "target": "reaction_10075942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038457", "target": "species_8855661" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038457", "target": "species_29416" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8855657", "target": "reaction_10038457" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29416", "target": "reaction_10034231" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038454", "target": "reaction_10038457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017653", "target": "species_10038454" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038464", "target": "species_162872" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038464", "target": "species_8855667" }, { "type": "reactant", "sub_type": "", "source": "species_8855663", "target": "reaction_10038464" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038461", "target": "reaction_10038464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012921", "target": "species_10038461" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052665", "target": "species_10052652" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052665", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052629", "target": "reaction_10052665" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052629", "target": "reaction_10054575" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052629", "target": "reaction_10054722" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052629", "target": "reaction_10054773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6U9", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075287", "target": "A0A3Q1M6U9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPY0", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066675", "target": "A0A3Q1LPY0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M633", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072582", "target": "A0A3Q1M633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N072", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071114", "target": "A0A3Q1N072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5A7", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010897", "target": "G5E5A7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ52", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085382", "target": "A0A3Q1LQ52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052652" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10077681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10054573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10054701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10054759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10054548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052494" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10052688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10076766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10084632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2T0", "target": "species_10084634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083797", "target": "A0A3Q1M2T0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052652", "target": "reaction_10077688" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052652", "target": "reaction_10076773" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052662", "target": "reaction_10052665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YQE1", "target": "species_10052662" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079217", "target": "Q7YQE1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079217", "target": "species_10052656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUB2", "target": "species_10052662" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076540", "target": "A0A3Q1MUB2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052521", "target": "species_10052519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052521", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10052521" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10052606" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10054550" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10052496" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10061538" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10052546" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052400", "target": "reaction_10052690" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077688", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077688", "target": "species_10077681" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077685", "target": "reaction_10077688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022569", "target": "species_10077685" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052461", "target": "species_10052400" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052461", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052377", "target": "reaction_10052461" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052458", "target": "reaction_10052461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ00", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071740", "target": "A0A3Q1MQ00" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M986", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078875", "target": "A0A3Q1M986" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPR6", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061536", "target": "E1BPR6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDW8", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028329", "target": "E1BDW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBP1", "target": "species_10052458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHN6", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010847", "target": "E1BHN6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLX6", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077005", "target": "A6QLX6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKQ9", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023104", "target": "E1BKQ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q07537", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081582", "target": "Q07537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM69", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087139", "target": "A0A3Q1LM69" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QA59", "target": "species_10052458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023106", "target": "F6QA59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052716", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052716", "target": "species_10052713" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052569", "target": "reaction_10052716" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10052656", "target": "reaction_10052716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052606", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052606", "target": "species_10052569" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052603", "target": "reaction_10052606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPZ8", "target": "species_10052603" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078680", "target": "A0A3Q1MPZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY64", "target": "species_10052603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY64", "target": "species_10063246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024024", "target": "A7YY64" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGN7", "target": "species_10052603" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063600", "target": "F1MGN7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX89", "target": "species_10052603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX89", "target": "species_10063246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084108", "target": "A0A3Q1LX89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVP5", "target": "species_10052603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVP5", "target": "species_10063246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079485", "target": "A0A3Q1LVP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSS4", "target": "species_10052603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSS4", "target": "species_10063246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005494", "target": "F1MSS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC83", "target": "species_10052603" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021344", "target": "Q0VC83" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054575", "target": "species_727810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054575", "target": "species_10054573" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054766", "target": "species_10054759" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054766", "target": "species_727810" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054701", "target": "reaction_10054766" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054763", "target": "reaction_10054766" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054722", "target": "species_727810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054722", "target": "species_10054701" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054773", "target": "species_727810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054773", "target": "species_10054573" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054770", "target": "reaction_10054773" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054550", "target": "species_10054548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054550", "target": "species_727810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052496", "target": "species_10052494" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052496", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061538", "target": "species_10052629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061538", "target": "species_205687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061535", "target": "reaction_10061538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC84", "target": "species_10061535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068688", "target": "Q0VC84" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX46", "target": "species_10061535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028542", "target": "Q3SX46" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052546", "target": "species_10052544" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052546", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052690", "target": "species_10052688" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052690", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076773", "target": "species_10076766" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076773", "target": "species_205687" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076770", "target": "reaction_10076773" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001899", "target": "species_10076770" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070145", "target": "species_158602" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070145", "target": "species_10070138" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070064", "target": "reaction_10070145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXR3", "target": "species_10070064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXR3", "target": "species_10070138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081541", "target": "F1MXR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVP0", "target": "species_10070064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVP0", "target": "species_10070138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020085", "target": "F1MVP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX27", "target": "species_10070064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX27", "target": "species_10070138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086844", "target": "A0A3Q1MX27" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10070064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10070138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2R9", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085538", "target": "A0A3Q1M2R9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK41", "target": "species_10070064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK41", "target": "species_10070138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061071", "target": "E1BK41" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_173594", "target": "reaction_10070145" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10070142", "target": "reaction_10070145" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047526", "target": "species_10070142" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077897", "target": "species_6788858" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077897", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6788865", "target": "reaction_10077897" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:87176", "target": "species_6788865" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:87177", "target": "species_6788865" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:87180", "target": "species_6788858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:87179", "target": "species_6788858" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077894", "target": "reaction_10077897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020456", "target": "species_10077894" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077883", "target": "species_71285" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077883", "target": "species_6788758" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6788753", "target": "reaction_10077883" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038408", "target": "species_10038394" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038406", "target": "reaction_10038408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10038406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10038394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037857" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP8", "target": "species_10037850" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021789", "target": "A0A452DIP8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021789", "target": "species_10037859" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038416", "target": "species_10038414" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038412", "target": "reaction_10038416" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009746", "target": "species_10038412" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009746", "target": "species_10038414" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009746", "target": "P22457" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038438", "target": "species_10038384" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038436", "target": "reaction_10038438" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043698", "target": "species_204635" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043698", "target": "species_29360" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043698", "target": "species_10043689" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043683", "target": "reaction_10043698" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043683", "target": "reaction_10043717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6EWQ7", "target": "species_10043683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6EWQ7", "target": "species_10043689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6EWQ7", "target": "species_10043708" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084447", "target": "Q6EWQ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN49", "target": "species_10043683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN49", "target": "species_10043689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN49", "target": "species_10043708" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079770", "target": "F1MN49" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_204628", "target": "reaction_10043698" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_204635", "target": "reaction_10044837" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_204635", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_204635", "target": "species_549250" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043695", "target": "reaction_10043698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6EWQ6", "target": "species_10043695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008200", "target": "Q6EWQ6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043717", "target": "species_29356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043717", "target": "species_10043708" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043717", "target": "species_29360" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043714", "target": "reaction_10043717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC53", "target": "species_10043714" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006935", "target": "Q0VC53" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060109", "target": "species_1663154" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060109", "target": "species_194697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060109", "target": "species_10060106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060079", "target": "reaction_10060109" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N665", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N665", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014061", "target": "F1N665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148F3", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148F3", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026877", "target": "Q148F3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ44", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ44", "target": "species_10060106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ44", "target": "species_10060038" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081469", "target": "A0A3Q1LZ44" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10060106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10060028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ3", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010988", "target": "A6QLZ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2T7", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2T7", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072310", "target": "G3N2T7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGQ6", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGQ6", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080500", "target": "A0A3Q1LGQ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN3", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN3", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017050", "target": "E1BIN3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J7", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7J7", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050377", "target": "A5D7J7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKH3", "target": "species_10060079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKH3", "target": "species_10060106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023672", "target": "E1BKH3" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060045", "target": "reaction_10060109" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055237", "target": "species_10060045" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091630", "target": "species_742343" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091630", "target": "species_10091628" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091620", "target": "reaction_10091630" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088614", "target": "reaction_10091630" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088614", "target": "reaction_10088617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000502", "target": "species_10088614" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071579", "target": "species_10071572" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071579", "target": "species_71285" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071569", "target": "reaction_10071579" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071576", "target": "reaction_10071579" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025327", "target": "species_10071576" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071566", "target": "species_111294" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071566", "target": "species_10038103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071566", "target": "species_76577" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071559", "target": "reaction_10071566" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31633", "target": "reaction_10071566" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31633", "target": "reaction_10033746" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31633", "target": "reaction_10049869" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31633", "target": "reaction_10049635" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071563", "target": "reaction_10071566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055382", "target": "species_10071563" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066409", "target": "species_10066407" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066405", "target": "reaction_10066409" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023029", "target": "species_10066405" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023029", "target": "species_10066407" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066369", "target": "reaction_10066409" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066369", "target": "reaction_10066380" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066369", "target": "reaction_10066372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAI5", "target": "species_10066369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002296", "target": "E1BAI5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTU0", "target": "species_10066369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080821", "target": "A0A3Q1MTU0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFX1", "target": "species_10066369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078136", "target": "A0A3Q1MFX1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066380", "target": "species_10066378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066376", "target": "reaction_10066380" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081472", "target": "species_10066376" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081472", "target": "species_10066378" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066372", "target": "species_10051814" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066355", "target": "reaction_10066372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077406", "target": "species_10077404" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056739", "target": "reaction_10077406" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077402", "target": "reaction_10077406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y1", "target": "species_10077402" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y1", "target": "species_10077404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y1", "target": "species_10075962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y1", "target": "species_10075968" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005174", "target": "Q3T0Y1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076001", "target": "species_10052288" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076001", "target": "species_10075998" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075996", "target": "reaction_10076001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S7", "target": "species_10075996" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S7", "target": "species_10075998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S7", "target": "species_10085342" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021435", "target": "E1B9S7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085345", "target": "species_10039539" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085345", "target": "species_10075998" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085342", "target": "reaction_10085345" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075952", "target": "species_10075949" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075944", "target": "reaction_10075952" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075984", "target": "species_10075982" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037956", "target": "reaction_10075984" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075980", "target": "reaction_10075984" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2J6", "target": "species_10075980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2J6", "target": "species_10075982" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064143", "target": "G3N2J6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS3", "target": "species_10075980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKS3", "target": "species_10075982" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020124", "target": "E1BKS3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPJ2", "target": "species_10075980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPJ2", "target": "species_10075982" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016836", "target": "A0A3S5ZPJ2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084931", "target": "species_10033408" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075838", "target": "reaction_10084931" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10084928", "target": "reaction_10084931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009023", "target": "species_10084928" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075970", "target": "species_10075968" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075966", "target": "reaction_10075970" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075966" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10075558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10078406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10033519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10033524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081468" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066709" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10080728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10078728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10069680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10069682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10084045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10084049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10088010" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10083070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10083074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081534" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10072547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10078666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10080809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10080795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10066762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P67939", "target": "species_10081520" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001420", "target": "P67939" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001420", "target": "species_10066422" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075962", "target": "reaction_10075970" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075989", "target": "species_10039539" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075989", "target": "species_10075944" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075986", "target": "reaction_10075989" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077371", "target": "species_10077369" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077367", "target": "reaction_10077371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061390", "target": "species_10077367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061390", "target": "E1BMF7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061390", "target": "species_10077373" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054896", "target": "reaction_10077371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044404", "target": "species_10054896" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044404", "target": "F1MBM6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBM6", "target": "species_10077369" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBM6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBM6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBM6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBM6", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMF7", "target": "species_10077369" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMF7", "target": "species_10077377" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077339", "target": "species_10077337" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077335", "target": "reaction_10077339" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025198", "target": "species_10077335" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025198", "target": "F1MUD4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUD4", "target": "species_10077337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUD4", "target": "species_10077344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUD4", "target": "species_10077346" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075550", "target": "species_10075422" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075550", "target": "species_10075547" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075418", "target": "reaction_10075550" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10075418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10075422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10091047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10042696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10091015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLP0", "target": "species_10091031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006418", "target": "A6QLP0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006418", "target": "species_10042669" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006418", "target": "species_10091013" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075902", "target": "species_10036828" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075902", "target": "species_10075899" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075897", "target": "reaction_10075902" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY85", "target": "species_10075897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MY85", "target": "species_10075899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087113", "target": "A0A3Q1MY85" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077393", "target": "species_10075488" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077393", "target": "species_10077390" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077388", "target": "reaction_10077393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ57", "target": "species_10077388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ57", "target": "species_10077390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ57", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ57", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079478", "target": "A0A3Q1LQ57" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC38", "target": "species_10077388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC38", "target": "species_10077390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC38", "target": "species_10077061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC38", "target": "species_10077067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079399", "target": "A0A3Q1MC38" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MME1", "target": "species_10077388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MME1", "target": "species_10077390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MME1", "target": "species_10077061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MME1", "target": "species_10077067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043704", "target": "A0A3Q1MME1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAX7", "target": "species_10077388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAX7", "target": "species_10077390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAX7", "target": "species_10077061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAX7", "target": "species_10077067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031172", "target": "A0A3Q1MAX7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075891", "target": "species_10033408" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075891", "target": "species_10075888" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075886", "target": "reaction_10075891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3P2", "target": "species_10075886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3P2", "target": "species_10075888" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077363", "target": "species_10077360" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077363", "target": "species_10075884" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077358", "target": "reaction_10077363" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKF9", "target": "species_10077358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKF9", "target": "species_10077360" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022310", "target": "A5PKF9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077331", "target": "species_10077328" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077331", "target": "species_10075547" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077326", "target": "reaction_10077331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW5", "target": "species_10077326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW5", "target": "species_10077328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW5", "target": "species_10039850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW5", "target": "species_10038031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW5", "target": "species_10038029" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077512", "target": "F1MRW5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077512", "target": "species_10039803" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077512", "target": "species_10038023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ0", "target": "species_10077326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ0", "target": "species_10077328" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026571", "target": "E1BLZ0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075561", "target": "species_10075558" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075561", "target": "species_10075547" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075556", "target": "reaction_10075561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHT6", "target": "species_10075556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHT6", "target": "species_10075558" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000967", "target": "A0A452DHT6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077034", "target": "species_10077031" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077034", "target": "species_10075884" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077029", "target": "reaction_10077034" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMX0", "target": "species_10077029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMX0", "target": "species_10077031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075352", "target": "A0A3Q1MMX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10077029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10077031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10077061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10077067" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10089339" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU1", "target": "species_10053120" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061377", "target": "F1MKU1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061377", "target": "species_10053104" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077292", "target": "species_10077189" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077292", "target": "species_10077289" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077171", "target": "reaction_10077292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSB6", "target": "species_10077171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSB6", "target": "species_10077189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029564", "target": "F1MSB6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077070", "target": "species_10075884" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077070", "target": "species_10077067" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077061", "target": "reaction_10077070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJZ0", "target": "species_10077061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJZ0", "target": "species_10077067" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010703", "target": "E1BJZ0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075808", "target": "species_10036828" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075808", "target": "species_10075805" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075801", "target": "reaction_10075808" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5C0", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5C0", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087295", "target": "A0A3Q1N5C0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAE2", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAE2", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047754", "target": "Q5EAE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0C8Z3", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0C8Z3", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011818", "target": "P0C8Z3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJW1", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJW1", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000926", "target": "A5PJW1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP59", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP59", "target": "species_10075805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP59", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061193", "target": "E1BP59" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ5", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ5", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009365", "target": "E1BKJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P9", "target": "species_10075801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E6P9", "target": "species_10075805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013438", "target": "G5E6P9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077379", "target": "species_10077377" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077375", "target": "reaction_10077379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3E8", "target": "species_10077375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3E8", "target": "species_10077377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3E8", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3E8", "target": "species_10073272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080740", "target": "A0A3Q1N3E8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077373", "target": "reaction_10077379" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077349", "target": "species_10077346" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077349", "target": "species_10039539" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077344", "target": "reaction_10077349" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL26", "target": "species_10077344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL26", "target": "species_10077346" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045376", "target": "E1BL26" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077317", "target": "species_10077314" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077317", "target": "species_10075547" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077308", "target": "reaction_10077317" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF69", "target": "species_10077308" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF69", "target": "species_10077314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074281", "target": "A0A3Q1LF69" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074281", "target": "species_10040063" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074281", "target": "species_10044912" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074281", "target": "species_10044910" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA7", "target": "species_10077308" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAA7", "target": "species_10077314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081720", "target": "A0A3Q1MAA7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075374", "target": "species_10075372" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075366", "target": "reaction_10075374" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075366", "target": "reaction_10076009" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002506", "target": "species_10075366" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002506", "target": "Q29RK4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075370", "target": "reaction_10075374" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075370", "target": "reaction_10091049" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007611", "target": "species_10075370" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007611", "target": "A6H799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H799", "target": "species_10075372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H799", "target": "species_10075394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H799", "target": "species_10091047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10075372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10076007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RK4", "target": "species_10077106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075397", "target": "species_10039539" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075397", "target": "species_10039537" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075394", "target": "reaction_10075397" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF75", "target": "species_10075394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067648", "target": "A0A3Q1MF75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J1", "target": "species_10075394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073722", "target": "A0A3Q1M4J1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME39", "target": "species_10075394" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008984", "target": "F1ME39" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086303", "target": "species_77502" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086303", "target": "species_10086296" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086293", "target": "reaction_10086303" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061405", "target": "species_10086293" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061405", "target": "species_10086296" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086300", "target": "reaction_10086303" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084035", "target": "species_10086300" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086319", "target": "species_71285" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086319", "target": "species_10086312" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038086", "target": "reaction_10086319" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038086", "target": "reaction_10086286" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087016", "target": "species_10038086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087016", "target": "species_10086312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087016", "target": "species_10086279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087016", "target": "P68103" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086316", "target": "reaction_10086319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085737", "target": "species_10086316" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086286", "target": "species_10086279" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086286", "target": "species_71285" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086283", "target": "reaction_10086286" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065836", "target": "species_10086283" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077744", "target": "species_71285" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10077744", "target": "species_10077737" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037000", "target": "reaction_10077744" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10037000", "target": "reaction_10048504" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077741", "target": "reaction_10077744" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046124", "target": "species_10077741" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083231", "target": "species_10083229" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037407", "target": "reaction_10083231" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083225", "target": "reaction_10083231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJA9", "target": "species_10083225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJA9", "target": "species_10083229" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043370", "target": "Q2HJA9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043370", "target": "species_10083195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKD6", "target": "species_10083225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKD6", "target": "species_10083229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKD6", "target": "species_10083806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083809", "target": "A5PKD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11017", "target": "species_10083225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11017", "target": "species_10083229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11017", "target": "species_10083806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008508", "target": "P11017" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083229", "target": "reaction_10083808" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083808", "target": "species_10083806" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083808", "target": "species_10083195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077947", "target": "species_10074859" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074840", "target": "reaction_10077947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "species_10074840" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "P15781" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "species_10091122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "species_10074838" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "species_10074844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045134", "target": "species_10074842" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074859", "target": "reaction_10074863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15781", "target": "species_10074859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15781", "target": "species_10074817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15781", "target": "species_10074825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15781", "target": "species_10075103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15781", "target": "species_10075115" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088922", "target": "species_10088920" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088918", "target": "reaction_10088922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10088918" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10088920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10075101" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10075103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10075123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10047288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35246", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008579", "target": "P35246" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088920", "target": "reaction_10091120" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074686", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074686", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074686", "target": "species_5684869" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5684863", "target": "reaction_10074686" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602402", "target": "species_5684863" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602402", "target": "species_5684869" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1602402", "target": "species_5686242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1602402", "target": "reaction_10059847" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5684869", "target": "reaction_10074833" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074683", "target": "reaction_10074686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019840", "target": "species_10074683" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074833", "target": "species_5686242" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074833", "target": "species_10074827" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074833", "target": "species_10074825" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074821", "target": "reaction_10074833" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10074821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10074827" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10074865" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10074867" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "A0A452DJB4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10075117" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10075021" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016672", "target": "species_10074861" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074817", "target": "reaction_10074833" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074827", "target": "reaction_10075105" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074825", "target": "reaction_10075105" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10074831", "target": "reaction_10074833" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035930", "target": "species_10074831" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091120", "target": "species_10075101" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075101", "target": "reaction_10075105" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074707", "target": "species_10074705" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074703", "target": "reaction_10074707" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024905", "target": "species_10074703" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024905", "target": "E1B9V4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074699", "target": "reaction_10074707" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050784", "target": "species_10074699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050784", "target": "A5PJN1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJN1", "target": "species_10074705" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9V4", "target": "species_10074705" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074869", "target": "species_10074867" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074865", "target": "reaction_10074869" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074867", "target": "reaction_10075023" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075125", "target": "species_10075111" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075125", "target": "species_10075123" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075125", "target": "species_10075117" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075125", "target": "species_10075099" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075125", "target": "species_10075115" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075103", "target": "reaction_10075125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10075082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10047288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ66", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068360", "target": "A0A3Q1NJ66" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJB4", "target": "species_10075103" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075099", "target": "reaction_10075105" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091124", "target": "species_10074838" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091122", "target": "reaction_10091124" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074838", "target": "reaction_10074857" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075095", "target": "species_10075070" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075095", "target": "species_76194" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075088", "target": "reaction_10075095" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075070", "target": "reaction_10075086" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075092", "target": "reaction_10075095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064000", "target": "species_10075092" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074857", "target": "species_10074844" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074857", "target": "species_10074842" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074857", "target": "species_10074840" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5685882", "target": "reaction_10074857" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5685882", "target": "reaction_10075023" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074854", "target": "reaction_10074857" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074854", "target": "reaction_10075023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJW6", "target": "species_10074854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008917", "target": "E1BJW6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N373", "target": "species_10074854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019640", "target": "F1N373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075019", "target": "species_10075017" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075015", "target": "reaction_10075019" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075017", "target": "reaction_10075086" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075017", "target": "reaction_10075105" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075084", "target": "species_10075082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075072", "target": "reaction_10075084" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075023", "target": "species_10075021" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075023", "target": "species_10074861" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074861", "target": "reaction_10074863" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074863", "target": "species_10074821" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074863", "target": "species_10074817" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075086", "target": "species_10075072" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075105", "target": "species_10075103" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081291", "target": "species_10081284" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081291", "target": "species_10043771" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081291", "target": "species_10043769" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081288", "target": "reaction_10081291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N0", "target": "species_10081288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N0", "target": "species_10081284" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026157", "target": "G5E5N0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026157", "target": "species_10081269" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026157", "target": "species_10081272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026157", "target": "species_10081276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBQ2", "target": "species_10081288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBQ2", "target": "species_10081284" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071531", "target": "A0A3Q1MBQ2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071531", "target": "species_10081282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIB8", "target": "species_10081288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071790", "target": "A0A3Q1MIB8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071790", "target": "species_10043771" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071790", "target": "species_10043769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071790", "target": "species_10043767" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081284", "target": "reaction_10081293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081274", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081274", "target": "species_10081272" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081269", "target": "reaction_10081274" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081272", "target": "reaction_10081278" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074441", "target": "reaction_10081274" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074441", "target": "reaction_10080457" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074441", "target": "reaction_10076341" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074441", "target": "reaction_10078720" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074441", "target": "reaction_10075173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040104", "target": "species_10074441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040104", "target": "E1BEI6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081293", "target": "species_10081288" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043767", "target": "reaction_10081293" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081278", "target": "species_10081276" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081276", "target": "reaction_10081286" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081286", "target": "species_10081284" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081282", "target": "reaction_10081286" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080457", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080457", "target": "species_10080455" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053725", "target": "reaction_10080457" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML53", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML53", "target": "species_10080455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083153", "target": "A0A3Q1ML53" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083153", "target": "G3N3R0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083153", "target": "A0A3Q1MWH2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083153", "target": "F1MJ74" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083153", "target": "A0A3Q1LXQ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3R0", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3R0", "target": "species_10080455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH2", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWH2", "target": "species_10080455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ74", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ74", "target": "species_10080455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXQ4", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXQ4", "target": "species_10080455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3X9", "target": "species_10053725" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3X9", "target": "species_10080455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057355", "target": "F1N3X9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081305", "target": "species_10081303" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081301", "target": "reaction_10081305" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033862", "target": "species_10081301" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033862", "target": "Q3T013" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052892", "target": "reaction_10081305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T013", "target": "species_10081303" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081323", "target": "species_10081321" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081319", "target": "reaction_10081323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KN9", "target": "species_10081319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KN9", "target": "species_10081321" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006594", "target": "Q32KN9" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081309", "target": "reaction_10081323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016994", "target": "species_10081309" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016994", "target": "Q0P5E1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081321", "target": "reaction_10081326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5E1", "target": "species_10081321" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081326", "target": "species_1524101" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500590", "target": "reaction_10081326" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500590", "target": "reaction_10058858" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1524101", "target": "species_5696037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524101", "target": "reaction_10059101" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080738", "target": "species_10080736" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10080734", "target": "reaction_10080738" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004413", "target": "species_10080734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004413", "target": "Q0VC75" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080736", "target": "reaction_10080789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC75", "target": "species_10080736" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080789", "target": "species_6799726" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080789", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6799725", "target": "reaction_10080789" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056702", "target": "species_29434" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056702", "target": "species_10056691" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056702", "target": "species_113528" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10056702" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10056757" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10041878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10033718" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10033716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10033681" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10051305" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10033788" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29406", "target": "reaction_10045036" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056667", "target": "reaction_10056702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075132", "target": "species_10056667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075132", "target": "species_10056691" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075132", "target": "A0A3Q1MIU5" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056699", "target": "reaction_10056702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG82", "target": "species_10056699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000101", "target": "F1MG82" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056679", "target": "species_10056677" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056671", "target": "reaction_10056679" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIU5", "target": "species_10056633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKG5", "target": "species_10056633" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077844", "target": "A0A3Q1MKG5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077844", "target": "species_10056675" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077844", "target": "species_10056704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077844", "target": "species_10056669" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077844", "target": "species_10056627" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056761", "target": "species_10056685" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056629", "target": "reaction_10056761" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056659", "target": "reaction_10056761" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056659", "target": "reaction_10056757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA0", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA0", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA0", "target": "species_10056716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA0", "target": "species_10056661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010744", "target": "A7MBA0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2B6", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2B6", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2B6", "target": "species_10056661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066920", "target": "A0A3Q1M2B6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5X0", "target": "species_10056659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5X0", "target": "species_10056685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5X0", "target": "species_10056661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037007", "target": "G5E5X0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056685", "target": "reaction_10056688" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056719", "target": "species_10056704" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056719", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056719", "target": "species_159939" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056675", "target": "reaction_10056719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10056719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073400" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069754" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073404" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073406" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069747" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073394" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073396" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069769" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073384" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10069796" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10073382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10064904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10066779" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113671", "target": "reaction_10084497" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10056719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073400" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069754" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073404" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073406" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069747" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073394" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073396" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069719" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069769" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073384" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10069796" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10073382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113685", "target": "reaction_10064904" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056716", "target": "reaction_10056719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUX2", "target": "species_10056716" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072600", "target": "A0A3Q1LUX2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056737", "target": "species_10056735" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056723", "target": "reaction_10056737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056733", "target": "reaction_10056737" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056735", "target": "reaction_10056754" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056688", "target": "species_10056661" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056688", "target": "species_10056681" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056683", "target": "reaction_10056688" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056754", "target": "species_10056751" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056754", "target": "species_10056745" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056747", "target": "reaction_10056754" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056751", "target": "reaction_10056759" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056757", "target": "species_29434" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056757", "target": "species_10056627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056757", "target": "species_113528" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056669", "target": "reaction_10056757" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056759", "target": "species_10056633" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044776", "target": "species_10044774" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044772", "target": "reaction_10044776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N021", "target": "species_10044772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N021", "target": "species_10044774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N021", "target": "species_10044792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044965", "target": "F1N021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX71", "target": "species_10044772" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX71", "target": "species_10044774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX71", "target": "species_10044792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079466", "target": "A0A3Q1LX71" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033775", "target": "reaction_10044776" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033775", "target": "reaction_10044784" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033775", "target": "reaction_10033778" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005575", "target": "species_10033775" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005575", "target": "P27117" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044774", "target": "reaction_10044794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27117", "target": "species_10044774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27117", "target": "species_10044792" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P27117", "target": "species_10044782" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044794", "target": "species_10044792" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044788", "target": "reaction_10044794" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072826", "target": "species_10044788" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072826", "target": "A3KMV9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMV9", "target": "species_10044792" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044784", "target": "species_10044782" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044780", "target": "reaction_10044784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079752", "target": "species_10044780" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079752", "target": "A0A3Q1MK02" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK02", "target": "species_10044782" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047519", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047519", "target": "species_10045007" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047512", "target": "reaction_10047519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI55", "target": "species_10047512" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066483", "target": "A0A3Q1MI55" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTG9", "target": "species_10047512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTG9", "target": "species_10084375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTG9", "target": "species_10084377" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077316", "target": "A0A3Q1MTG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LME0", "target": "species_10047512" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LME0", "target": "species_10047517" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075439", "target": "A0A3Q1LME0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075439", "target": "species_10047510" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075439", "target": "species_10052464" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10047517", "target": "reaction_10047519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047536", "target": "species_10047534" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052466", "target": "species_10047517" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047510", "target": "reaction_10052466" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047510", "target": "reaction_10052471" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047515", "target": "reaction_10052466" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10052464", "target": "reaction_10052466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052471", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10052471", "target": "species_10052464" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_427893", "target": "reaction_10052471" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030539", "target": "species_427893" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071800", "target": "species_74126" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10071800" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10048526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057588" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10033561" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10044076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10071824" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10071819" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10071876" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057639" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10045466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10045455" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10045444" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057399" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10048618" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10048804" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057569" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057665" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057656" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057682" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10057616" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29804", "target": "reaction_10065875" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10057418" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74126", "target": "species_10034154" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10054318" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10091521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10053180" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10048594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_74126", "target": "reaction_10053210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_74126", "target": "species_10071921" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071797", "target": "reaction_10071800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHV0", "target": "species_10071797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHV0", "target": "species_10071821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001530", "target": "Q2KHV0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKS7", "target": "species_10071797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKS7", "target": "species_10071821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037245", "target": "Q2NKS7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT75", "target": "species_10071797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT75", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087044", "target": "A0A3Q1MT75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPA7", "target": "species_10071797" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069177", "target": "A0A3Q1LPA7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059961", "target": "species_428633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059961", "target": "species_1605647" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605590", "target": "reaction_10059961" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071483", "target": "species_5339515" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1638840", "target": "reaction_10071483" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071480", "target": "reaction_10071483" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010025", "target": "species_10071480" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084410", "target": "species_8856242" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084410", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8856243", "target": "reaction_10084410" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1605641", "target": "species_8856243" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605641", "target": "reaction_10059968" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28424", "target": "species_8856243" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1605610", "target": "species_8856242" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605610", "target": "reaction_10059954" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1605610", "target": "species_10059929" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28648", "target": "species_8856242" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084407", "target": "reaction_10084410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DI2", "target": "species_10084407" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005893", "target": "Q58DI2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060316", "target": "species_429807" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060316", "target": "species_1610735" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429776", "target": "reaction_10060316" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429776", "target": "reaction_10060012" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_429776", "target": "reaction_10049182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429807", "target": "reaction_10060021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429807", "target": "reaction_10060309" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429807", "target": "reaction_10049182" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060313", "target": "reaction_10060316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002552", "target": "species_10060313" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059984", "target": "species_428633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059984", "target": "species_1605618" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605649", "target": "reaction_10059984" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10059954", "target": "species_10059929" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059927", "target": "reaction_10059954" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029099", "target": "species_10059927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029099", "target": "E1BI28" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059929", "target": "reaction_10059944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI28", "target": "species_10059929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI28", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI28", "target": "species_10080433" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060021", "target": "species_1606609" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060021", "target": "species_1861754" }, { "type": "catalyst", "sub_type": "", "source": "species_10060018", "target": "reaction_10060021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060309", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060309", "target": "species_1638840" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060306", "target": "reaction_10060309" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064397", "target": "species_10060306" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059991", "target": "species_1605750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059991", "target": "species_1605673" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605713", "target": "reaction_10059991" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059988", "target": "reaction_10059991" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020758", "target": "species_10059988" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059977", "target": "species_1605637" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059977", "target": "species_1605601" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605716", "target": "reaction_10059977" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059974", "target": "reaction_10059977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B725", "target": "species_10059974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B725", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B725", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025636", "target": "E1B725" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060041", "target": "species_1609650" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060041", "target": "species_1609649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1609648", "target": "reaction_10060041" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060038", "target": "reaction_10060041" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071497", "target": "species_5340299" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5340315", "target": "reaction_10071497" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071494", "target": "reaction_10071497" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003355", "target": "species_10071494" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10059944", "target": "species_10059927" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059944", "target": "species_1605658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059944", "target": "species_1605641" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060012", "target": "species_429807" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060012", "target": "species_1610735" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060009", "target": "reaction_10060012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N588", "target": "species_10060009" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010706", "target": "F1N588" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059951", "target": "species_1605716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059951", "target": "species_1605658" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1605608", "target": "reaction_10059951" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059948", "target": "reaction_10059951" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060302", "target": "species_1660674" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060302", "target": "species_205687" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_744227", "target": "reaction_10060302" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428270", "target": "reaction_10060302" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428270", "target": "reaction_10048889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428270", "target": "reaction_10049189" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060299", "target": "reaction_10060302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043826", "target": "species_10060299" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059968", "target": "species_1605601" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059968", "target": "species_428639" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059965", "target": "reaction_10059968" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019755", "target": "species_10059965" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048986", "target": "species_428671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048986", "target": "species_428686" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428203", "target": "reaction_10048986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428203", "target": "reaction_10049004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428203", "target": "reaction_10049007" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428203", "target": "reaction_10091936" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428671", "target": "reaction_10076151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428686", "target": "reaction_10059082" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428686", "target": "reaction_10059130" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048983", "target": "reaction_10048986" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048983", "target": "reaction_10048988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080801", "target": "species_10048983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049116", "target": "species_10049110" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049116", "target": "species_428270" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049108", "target": "reaction_10049116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDZ9", "target": "species_10049108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDZ9", "target": "species_10049110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDZ9", "target": "species_10049158" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDZ9", "target": "species_10049100" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023164", "target": "A2VDZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJG0", "target": "species_10049108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJG0", "target": "species_10049110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJG0", "target": "species_10049158" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJG0", "target": "species_10049100" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053250", "target": "A0A452DJG0" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428256", "target": "species_10049108" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428256", "target": "reaction_10048903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428256", "target": "reaction_10049143" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428256", "target": "reaction_10076389" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428256", "target": "species_5696348" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_428256", "target": "species_10076961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GKI7", "target": "species_10049108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GKI7", "target": "species_10049110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9GKI7", "target": "species_10049158" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056797", "target": "Q9GKI7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056797", "target": "species_10049147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056797", "target": "species_10049124" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056797", "target": "species_10049119" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049110", "target": "reaction_10049143" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049110", "target": "reaction_10049121" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049114", "target": "reaction_10049116" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049114", "target": "reaction_10085316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027095", "target": "species_10049114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048860", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048860", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048860", "target": "species_428182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10048860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10059121" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10059073" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10060207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10090175" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10086371" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200736", "target": "reaction_10090647" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9695889", "target": "reaction_10048860" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048843", "target": "reaction_10048860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E978", "target": "species_10048843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018578", "target": "Q5E978" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIK4", "target": "species_10048843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085219", "target": "Q0IIK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHG1", "target": "species_10048843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002872", "target": "Q3MHG1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM3", "target": "species_10048843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027289", "target": "A5PKM3" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10048858", "target": "reaction_10048860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD15", "target": "species_10048858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD15", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD15", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD15", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD15", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018402", "target": "Q0VD15" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RQ9", "target": "species_10048858" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016673", "target": "Q29RQ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E972", "target": "species_10048858" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027540", "target": "Q5E972" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048988", "target": "species_428686" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048988", "target": "species_428663" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428275", "target": "reaction_10048988" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428275", "target": "reaction_10048978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428663", "target": "reaction_10076833" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10049182", "target": "species_429802" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10049182", "target": "species_429807" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049182", "target": "species_429776" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049182", "target": "species_112275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429802", "target": "reaction_10049182" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429802", "target": "reaction_10063368" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429802", "target": "reaction_10059856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429802", "target": "reaction_10059858" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429802", "target": "reaction_10074360" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049179", "target": "reaction_10049182" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072919", "target": "species_10049179" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048978", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048978", "target": "species_428694" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048975", "target": "reaction_10048978" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048975", "target": "reaction_10049007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNA1", "target": "species_10048975" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005808", "target": "A0JNA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0W7", "target": "species_10048975" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067390", "target": "A0A3Q1N0W7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048917", "target": "species_428237" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048917", "target": "species_3632878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025544", "target": "reaction_10048917" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048914", "target": "reaction_10048917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052101", "target": "species_10048914" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049161", "target": "species_10049110" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049161", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049158", "target": "reaction_10049161" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049163", "target": "species_10049158" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049100", "target": "reaction_10049163" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049147", "target": "reaction_10049163" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082058", "target": "species_2453691" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082058", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082058", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6808468", "target": "reaction_10082058" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082055", "target": "reaction_10082058" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3Q4", "target": "species_10082055" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085198", "target": "A0A3Q1M3Q4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPA0", "target": "species_10082055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPA0", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPA0", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPA0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPA0", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076578", "target": "Q1JPA0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076578", "target": "species_10076830" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048910", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048910", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048910", "target": "species_9025544" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428126", "target": "reaction_10048910" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048907", "target": "reaction_10048910" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012243", "target": "species_10048907" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048896", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048896", "target": "species_428275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428163", "target": "reaction_10048896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428163", "target": "reaction_10048882" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048893", "target": "reaction_10048896" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048893", "target": "reaction_10091941" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074462", "target": "species_10048893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074462", "target": "A0A3Q1MBG6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049154", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049154", "target": "species_10049147" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049124", "target": "reaction_10049154" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049151", "target": "reaction_10049154" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022345", "target": "species_10049151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10048903", "target": "species_29356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10048903", "target": "species_428256" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048903", "target": "species_428193" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048903", "target": "species_428198" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_428193", "target": "reaction_10048903" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428193", "target": "reaction_10091941" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_428198", "target": "reaction_10048903" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048900", "target": "reaction_10048903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010648", "target": "species_10048900" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048889", "target": "species_428248" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048889", "target": "species_8934421" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048886", "target": "reaction_10048889" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014354", "target": "species_10048886" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048882", "target": "species_428126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048882", "target": "species_76194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048879", "target": "reaction_10048882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVP2", "target": "species_10048879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082150", "target": "A0A3Q1MVP2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJ30", "target": "species_10048879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080491", "target": "A0A3Q1MJ30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUG2", "target": "species_10048879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036524", "target": "A4FUG2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7K4", "target": "species_10048879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052579", "target": "A5D7K4" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049141", "target": "species_10049124" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049141", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049119", "target": "reaction_10049141" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049138", "target": "reaction_10049141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9F5", "target": "species_10049138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081006", "target": "A0A3Q1N9F5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIA2", "target": "species_10049138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020721", "target": "F1MIA2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7L9", "target": "species_10049138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070039", "target": "E1B7L9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049143", "target": "species_10049108" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076151", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076151", "target": "species_3632881" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076151", "target": "species_73473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076148", "target": "reaction_10076151" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049004", "target": "species_428682" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049004", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049001", "target": "reaction_10049004" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIK4", "target": "species_10049001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069794", "target": "A0A3Q1MIK4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069794", "target": "species_10048992" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZE3", "target": "species_10049001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015460", "target": "Q3SZE3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049007", "target": "species_428682" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049007", "target": "species_29372" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049121", "target": "species_10049119" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049121", "target": "species_10049100" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076833", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076833", "target": "species_3632881" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076833", "target": "species_73473" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076830", "target": "reaction_10076833" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091936", "target": "species_419305" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091933", "target": "reaction_10091936" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009765", "target": "species_10091933" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048995", "target": "species_109277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048995", "target": "species_428662" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048992", "target": "reaction_10048995" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076389", "target": "species_5693768" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076389", "target": "species_29356" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076386", "target": "reaction_10076389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016212", "target": "species_10076386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10049189", "target": "species_429785" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10049189", "target": "species_428270" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049189", "target": "species_429773" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049189", "target": "species_429789" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_429773", "target": "reaction_10049189" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_429789", "target": "reaction_10049189" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049186", "target": "reaction_10049189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082007", "target": "species_10049186" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091941", "target": "species_428203" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091941", "target": "species_29370" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10091939", "target": "reaction_10091941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBG6", "target": "species_10091939" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043933", "target": "species_209849" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043933", "target": "species_71112" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29506", "target": "reaction_10043933" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71112", "target": "reaction_10033935" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043930", "target": "reaction_10043933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN0", "target": "species_10043930" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077835", "target": "A0A3Q1MAN0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073477", "target": "species_5662670" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5662665", "target": "reaction_10073477" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073474", "target": "reaction_10073477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC37", "target": "species_10073474" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034881", "target": "F1MC37" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044216", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044216", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044216", "target": "species_215075" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044213", "target": "reaction_10044216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148E6", "target": "species_10044213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015892", "target": "Q148E6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044195", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044195", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044195", "target": "species_352318" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044192", "target": "reaction_10044195" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044260", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044260", "target": "species_113564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044260", "target": "species_215062" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044257", "target": "reaction_10044260" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035958", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035958", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035958", "target": "species_42373" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035955", "target": "reaction_10035958" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048504", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048504", "target": "species_74112" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048501", "target": "reaction_10048504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7D0", "target": "species_10048501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014410", "target": "E1B7D0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LST7", "target": "species_10048501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077819", "target": "A0A3Q1LST7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072522", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072522", "target": "species_74016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072522", "target": "species_425958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5626313", "target": "reaction_10072522" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_167012", "target": "reaction_10072522" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072519", "target": "reaction_10072522" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006382", "target": "species_10072519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048526", "target": "species_74126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048526", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048526", "target": "species_74112" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048523", "target": "reaction_10048526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD60", "target": "species_10048523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008703", "target": "F1MD60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M073", "target": "species_10048523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074844", "target": "A0A3Q1M073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM98", "target": "species_10048523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061324", "target": "E1BM98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGG7", "target": "species_10048523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015768", "target": "E1BGG7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048533", "target": "species_425810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048533", "target": "species_74112" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_425815", "target": "reaction_10048533" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048530", "target": "reaction_10048533" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070502", "target": "species_10048530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070502", "target": "species_10087643" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038895", "target": "species_76633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038895", "target": "species_113526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038895", "target": "species_163953" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73663", "target": "reaction_10038895" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038882", "target": "reaction_10038895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23934", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23934", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23934", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013078", "target": "P23934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04394", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04394", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04394", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006405", "target": "P04394" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7B1", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7B1", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7B1", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065530", "target": "A0A3Q1M7B1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065530", "target": "A0A3Q1N0E1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0E1", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0E1", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0E1", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15690", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15690", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15690", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029301", "target": "P15690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK0", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK0", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIK0", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019529", "target": "A0A452DIK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG52", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG52", "target": "species_10080511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG52", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075840", "target": "A0A3Q1MG52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02379", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02379", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077219", "target": "Q02379" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077219", "target": "species_10038704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q85BD6", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q85BD6", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q85BD6", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060577", "target": "Q85BD6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060577", "target": "species_10038712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH1", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH1", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH1", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH1", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH1", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060571", "target": "Q6QTH1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42026", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42026", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42026", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42026", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42026", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053067", "target": "P42026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34943", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34943", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34943", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34943", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P34943", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007189", "target": "P34943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02374", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02374", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02374", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02374", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02374", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029003", "target": "Q02374" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFL6", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFL6", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFL6", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFL6", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFL6", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035646", "target": "A0A3Q1LFL6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA0", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA0", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA0", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA0", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFA0", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071194", "target": "A0A3Q1MFA0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071194", "target": "A0A3Q1M144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M144", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M144", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M144", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M144", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M144", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02377", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02377", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02377", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02377", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02377", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007925", "target": "Q02377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02365", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02365", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02365", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02365", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02365", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016957", "target": "Q02365" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02827", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024209", "target": "Q02827" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23935", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23935", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23935", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23935", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23935", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012287", "target": "P23935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW79", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW79", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW79", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW79", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW79", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067852", "target": "A0A3Q1LW79" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42029", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42029", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42029", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42029", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P42029", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005628", "target": "P42029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02369", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02369", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02369", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02369", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02369", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027191", "target": "Q02369" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02373", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02373", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02373", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02373", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02373", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012542", "target": "Q02373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB4", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB4", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB4", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB4", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB4", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012512", "target": "A0A452DIB4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02368", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02368", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02368", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02368", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02368", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016768", "target": "Q02368" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG5", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG5", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG5", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG5", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG5", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070642", "target": "Q8HXG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05752", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05752", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05752", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05752", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05752", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077911", "target": "Q05752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02370", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02370", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02370", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02370", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02370", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020018", "target": "Q02370" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LID6", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LID6", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LID6", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LID6", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LID6", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072963", "target": "A0A3Q1LID6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95KV7", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95KV7", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95KV7", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95KV7", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95KV7", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010276", "target": "Q95KV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02371", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02371", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02371", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02371", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02371", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010193", "target": "Q02371" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02380", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02380", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02380", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02380", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02380", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003197", "target": "Q02380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG6", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG6", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG6", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG6", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HXG6", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025322", "target": "Q8HXG6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBM6", "target": "species_10038730" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084872", "target": "A0A3Q1MBM6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTH0", "target": "species_10038730" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060548", "target": "Q6QTH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03924", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03924", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03924", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03924", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03924", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060562", "target": "P03924" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060562", "target": "species_10038716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02367", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02367", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02367", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02367", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02367", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007761", "target": "Q02367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007761", "target": "species_10038720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03898", "target": "species_10038740" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060547", "target": "P03898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA03", "target": "species_10038740" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030501", "target": "Q5EA03" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03910", "target": "species_10038882" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03910", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03910", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060552", "target": "P03910" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060552", "target": "species_10038708" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038893", "target": "reaction_10038895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK72", "target": "species_10038893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006115", "target": "F1MK72" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM6", "target": "species_10038893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005722", "target": "Q1RMM6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080521", "target": "species_10080505" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080503", "target": "reaction_10080521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP25", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP25", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP25", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP25", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP25", "target": "species_10080501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085097", "target": "A0A3Q1MP25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX05", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX05", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX05", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX05", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX05", "target": "species_10080501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAZ2", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAZ2", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAZ2", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAZ2", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAZ2", "target": "species_10080501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074751", "target": "E1BAZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS4", "target": "species_10080503" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS4", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS4", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS4", "target": "species_10080513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCS4", "target": "species_10080501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027441", "target": "E1BCS4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080485", "target": "reaction_10080521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJI2", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJI2", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJI2", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJI2", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025174", "target": "Q2HJI2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUH5", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUH5", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUH5", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUH5", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004122", "target": "A4FUH5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YVD7", "target": "species_10080485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YVD7", "target": "species_10080505" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YVD7", "target": "species_10080507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YVD7", "target": "species_10080513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009959", "target": "A7YVD7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080505", "target": "reaction_10080517" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080515", "target": "species_10080513" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038704", "target": "reaction_10080515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080511", "target": "reaction_10080515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080507", "target": "reaction_10080515" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080517", "target": "species_10080507" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038708", "target": "reaction_10080517" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038712", "target": "reaction_10080517" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080519", "target": "species_10080503" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038740", "target": "reaction_10080519" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080501", "target": "reaction_10080519" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038720", "target": "reaction_10080519" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038716", "target": "reaction_10080519" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038730", "target": "reaction_10080519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038647", "target": "species_10038548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038647", "target": "species_163953" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038647", "target": "species_113521" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038546", "target": "reaction_10038647" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:38573", "target": "species_10038546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62894", "target": "species_10038546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62894", "target": "species_10038548" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007918", "target": "P62894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007918", "target": "species_10037239" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007918", "target": "species_10037211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007918", "target": "species_10075353" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038548", "target": "reaction_10067735" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:38574", "target": "species_10038548" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038606", "target": "reaction_10038647" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038606", "target": "reaction_10092312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH77", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH77", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006474", "target": "E1BH77" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68530", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68530", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060549", "target": "P68530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB8", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKB8", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080485", "target": "A0A3Q1LKB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTG5", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTG5", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060566", "target": "Q6QTG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBD7", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBD7", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076309", "target": "A0A3Q1MBD7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTG9", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QTG9", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060569", "target": "Q6QTG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB49", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB49", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067651", "target": "A0A3Q1MB49" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28694", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28694", "target": "species_10038645" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28694", "target": "species_10076853" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28694", "target": "species_10076881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q01321", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q01321", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014801", "target": "Q01321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00426", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00426", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022949", "target": "P00426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00430", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00430", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079150", "target": "P00430" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00423", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00423", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053881", "target": "P00423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13182", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13182", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071537", "target": "P13182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T061", "target": "species_10038606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T061", "target": "species_10038645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000943", "target": "Q3T061" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038643", "target": "reaction_10038647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H784", "target": "species_10038643" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016742", "target": "A6H784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQS6", "target": "species_10038643" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067855", "target": "A0A3Q1MQS6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJK7", "target": "species_10038643" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013031", "target": "E1BJK7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPX9", "target": "species_10038643" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021773", "target": "E1BPX9" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038611", "target": "reaction_10038647" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020289", "target": "species_10038611" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038625", "target": "reaction_10038647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMW4", "target": "species_10038625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082257", "target": "A0A3Q1MMW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5P2", "target": "species_10038625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007094", "target": "F1N5P2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMH3", "target": "species_10038625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001069", "target": "Q1RMH3" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10038645", "target": "reaction_10038647" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9709335", "target": "species_10038645" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9709335", "target": "species_10092212" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9709335", "target": "reaction_10092308" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084313", "target": "species_10074027" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084133", "target": "reaction_10084313" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074027", "target": "reaction_10084131" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084185", "target": "species_10084183" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084185", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084177", "target": "reaction_10084185" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084183", "target": "reaction_10084326" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084153", "target": "species_10084151" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084153" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084379" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084149" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084311" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084393" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084352" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074025", "target": "reaction_10084135" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085755", "target": "species_10084157" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074005", "target": "reaction_10085755" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084137", "target": "reaction_10085755" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084137", "target": "reaction_10085757" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084137", "target": "reaction_10084141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084157", "target": "reaction_10084187" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084187", "target": "species_10084159" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073999", "target": "reaction_10084187" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084379", "target": "species_10084377" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084375", "target": "reaction_10084379" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085757", "target": "species_10084161" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074017", "target": "reaction_10085757" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084161", "target": "reaction_10084198" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084190", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084190", "target": "species_10074025" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084167", "target": "reaction_10084190" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084309", "target": "species_10084177" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084175", "target": "reaction_10084309" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084149", "target": "species_10084147" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084145", "target": "reaction_10084149" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084145", "target": "reaction_10092137" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081071", "target": "species_10084145" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081071", "target": "A0A3Q1LNN8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNN8", "target": "species_10084147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNN8", "target": "species_10092135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNN8", "target": "species_10092156" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNN8", "target": "species_10092161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNN8", "target": "species_10092163" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084311", "target": "species_10074031" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084169", "target": "species_10084167" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084165", "target": "reaction_10084169" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084393", "target": "species_10084391" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084389", "target": "reaction_10084393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX40", "target": "species_10084389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX40", "target": "species_10084391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009662", "target": "Q3SX40" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084330", "target": "species_10084328" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084141", "target": "species_10084139" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073976", "target": "reaction_10084141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084139", "target": "reaction_10084196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084352", "target": "species_10084350" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084348", "target": "reaction_10084352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3X9", "target": "species_10084348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3X9", "target": "species_10084350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064953", "target": "G3N3X9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB8", "target": "species_10084348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB8", "target": "species_10084350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004337", "target": "A7MBB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ7", "target": "species_10084348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ7", "target": "species_10084350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071968", "target": "A4IFJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR5", "target": "species_10084348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR5", "target": "species_10084350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064819", "target": "Q0VCR5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084131", "target": "species_10074029" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084194", "target": "species_10084175" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084192", "target": "reaction_10084194" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084196", "target": "species_10084155" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073972", "target": "reaction_10084196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084135", "target": "species_10084133" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084198", "target": "species_10084163" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074013", "target": "reaction_10084198" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084326", "target": "species_10084324" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061049", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061049", "target": "species_2023901" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023891", "target": "reaction_10061049" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023901", "target": "reaction_10061017" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023901", "target": "reaction_10060993" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061028", "target": "reaction_10061049" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061028", "target": "reaction_10061128" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061028", "target": "reaction_10061137" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061028", "target": "reaction_10061031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014872", "target": "species_10061028" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061017", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061017", "target": "species_2023922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023922", "target": "reaction_10061131" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060948", "target": "reaction_10061017" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060948", "target": "reaction_10061131" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060948", "target": "reaction_10061052" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060948", "target": "reaction_10061119" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060948", "target": "reaction_10060951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II95", "target": "species_10060948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015405", "target": "Q0II95" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015405", "target": "species_10060953" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4Q6", "target": "species_10060948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030644", "target": "F6Q4Q6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061128", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061128", "target": "species_2023901" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023892", "target": "reaction_10061128" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061131", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061131", "target": "species_2023948" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061052", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061052", "target": "species_2023940" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023929", "target": "reaction_10061052" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023940", "target": "reaction_10061119" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061119", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061119", "target": "species_2023941" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061137", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061137", "target": "species_2023891" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023907", "target": "reaction_10061137" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060993", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060993", "target": "species_2023929" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060990", "target": "reaction_10060993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015737", "target": "species_10060990" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015737", "target": "species_10061008" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061031", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061031", "target": "species_2023901" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023935", "target": "reaction_10061031" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060951", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060951", "target": "species_2023931" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023932", "target": "reaction_10060951" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067955", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067955", "target": "species_10067952" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067950", "target": "reaction_10067955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Q0", "target": "species_10067950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Q0", "target": "species_10067952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Q0", "target": "species_10067948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Q0", "target": "species_10068018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021199", "target": "F1N6Q0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E954", "target": "species_10067950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E954", "target": "species_10067952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E954", "target": "species_10067948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E954", "target": "species_10068018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021637", "target": "Q5E954" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ94", "target": "species_10067950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ94", "target": "species_10067952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ94", "target": "species_10067948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ94", "target": "species_10068018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004890", "target": "Q2HJ94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10067950" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10067952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10068020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10071123" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10071232" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10071171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10071195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27975", "target": "species_10071125" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017500", "target": "Q27975" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067948", "target": "reaction_10067955" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068022", "target": "species_10067950" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068020", "target": "reaction_10068022" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068018", "target": "reaction_10068022" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065708", "target": "species_10065705" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065697", "target": "reaction_10065708" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065697", "target": "reaction_10065726" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011761", "target": "species_10065697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011761", "target": "F1MW01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW01", "target": "species_10065705" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW01", "target": "species_10065724" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065726", "target": "species_10065724" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065722", "target": "reaction_10065726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N089", "target": "species_10065722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N089", "target": "species_10065724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066220", "target": "G3N089" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066220", "target": "A0A452DIH5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066220", "target": "G3MYU8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIH5", "target": "species_10065722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIH5", "target": "species_10065724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYU8", "target": "species_10065722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYU8", "target": "species_10065724" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091145", "target": "species_10091143" }, { "type": "reactant", "sub_type": "", "source": "species_9624879", "target": "reaction_10091145" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091134", "target": "reaction_10091145" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP2", "target": "species_10091134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP2", "target": "species_10091143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP2", "target": "species_10043519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP2", "target": "species_10043501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP2", "target": "species_10063558" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033457", "target": "G3MZP2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033457", "target": "G5E619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E619", "target": "species_10091134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E619", "target": "species_10091143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E619", "target": "species_10043519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E619", "target": "species_10043501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E619", "target": "species_10063558" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091141", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091141", "target": "species_10091134" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043519", "target": "reaction_10091141" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091138", "target": "reaction_10091141" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066656", "target": "species_10091138" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091132", "target": "species_10091130" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044128", "target": "reaction_10091132" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044128", "target": "reaction_10063564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008650", "target": "species_10044128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008650", "target": "E1BFV0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091128", "target": "reaction_10091132" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011125", "target": "species_10091128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011125", "target": "A6QQV8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011125", "target": "species_10041490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQV8", "target": "species_10091130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10091130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10052187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10044132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10044140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10060344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10063558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV0", "target": "species_10060332" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091656", "target": "species_10091654" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091652", "target": "reaction_10091656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065503", "target": "species_10091652" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065503", "target": "G3X8E2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091648", "target": "reaction_10091656" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091648", "target": "reaction_10091661" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R5", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R5", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7R5", "target": "species_10091646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021129", "target": "F1N7R5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021129", "target": "species_10091640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B828", "target": "species_10091648" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B828", "target": "species_10091654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B828", "target": "species_10091644" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B828", "target": "species_10091646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B828", "target": "species_10091632" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020642", "target": "E1B828" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020642", "target": "species_10070769" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X8E2", "target": "species_10091654" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091658", "target": "species_10091646" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091644", "target": "reaction_10091658" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091640", "target": "reaction_10091658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091661", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091661", "target": "species_10040834" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091661", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091634", "target": "species_10091632" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052771", "target": "reaction_10091634" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070769", "target": "reaction_10091634" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091663", "target": "species_10039906" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039904", "target": "reaction_10091663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020389", "target": "species_10039904" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020389", "target": "F1MTU0" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039900", "target": "reaction_10091663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002226", "target": "species_10039900" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002226", "target": "P0CG11" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039896", "target": "reaction_10091663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026311", "target": "species_10039896" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026311", "target": "E1B8Q4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Q4", "target": "species_10039906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P0CG11", "target": "species_10039906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTU0", "target": "species_10039906" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057418", "target": "species_29804" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057415", "target": "reaction_10057418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O19182", "target": "species_10057415" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010914", "target": "O19182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4V6", "target": "species_10057415" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078632", "target": "A0A3Q1M4V6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCI4", "target": "species_10057415" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000089", "target": "E1BCI4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064591", "target": "species_2162207" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064591", "target": "species_159450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2162214", "target": "reaction_10064591" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2162213", "target": "reaction_10064591" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064588", "target": "reaction_10064591" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007549", "target": "species_10064588" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046968", "target": "species_29406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046968", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046968", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046968", "target": "species_29364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_389545", "target": "reaction_10046968" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046965", "target": "reaction_10046968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10046965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T8A5", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027348", "target": "A0A140T8A5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058524", "target": "species_1475054" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058524", "target": "species_1474179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1474124", "target": "reaction_10058524" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058521", "target": "reaction_10058524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA59", "target": "species_10058521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA59", "target": "species_10058778" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030411", "target": "A0A3Q1MA59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058511", "target": "species_1474124" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058511", "target": "species_29460" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058500", "target": "reaction_10058511" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058500", "target": "reaction_10058514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ14", "target": "species_10058500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ14", "target": "species_10058509" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009020", "target": "F1MZ14" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29502", "target": "reaction_10058511" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29502", "target": "reaction_10052040" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29502", "target": "reaction_10052043" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10058509", "target": "reaction_10058511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L41", "target": "species_10058509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L41", "target": "species_10058507" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017922", "target": "Q32L41" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058785", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058785", "target": "species_10058521" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058778", "target": "reaction_10058785" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058782", "target": "reaction_10058785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003877", "target": "species_10058782" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058514", "target": "species_10058509" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058507", "target": "reaction_10058514" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085853", "target": "species_10085851" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085849", "target": "reaction_10085853" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8874708", "target": "species_10085849" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8874708", "target": "species_10085851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8874708", "target": "reaction_10085855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N086", "target": "species_10085849" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N086", "target": "species_10085851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030426", "target": "F1N086" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030426", "target": "species_10085847" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085855", "target": "species_10085849" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085847", "target": "reaction_10085855" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081928", "target": "species_6806362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6806366", "target": "reaction_10081928" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6806366", "target": "reaction_10038427" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081925", "target": "reaction_10081928" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064807", "target": "species_10081925" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038427", "target": "species_6806362" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038422", "target": "reaction_10038427" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038422", "target": "reaction_10090493" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6B4J2", "target": "species_10038422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6B4J2", "target": "species_10038425" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000519", "target": "Q6B4J2" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10038425", "target": "reaction_10038427" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090493", "target": "species_10038425" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9035082", "target": "reaction_10090493" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081935", "target": "species_6806362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081935", "target": "species_6806656" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6806891", "target": "reaction_10081935" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6806657", "target": "reaction_10081935" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081932", "target": "reaction_10081935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018617", "target": "species_10081932" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054393", "target": "species_10054388" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054393", "target": "species_29366" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054390", "target": "reaction_10054393" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054390", "target": "reaction_10066247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG1", "target": "species_10054390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG1", "target": "species_10054388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078995", "target": "A7MBG1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078995", "target": "species_10054386" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10054388" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10065443" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975590", "target": "reaction_10054395" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_5246487" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10070969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10065439" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10035556" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_975590", "target": "species_10065681" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035574", "target": "reaction_10054393" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066249", "target": "species_10065443" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473610", "target": "reaction_10066249" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035554", "target": "reaction_10066249" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035554", "target": "reaction_10065441" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035554", "target": "reaction_10035558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU75", "target": "species_10035554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU75", "target": "species_10065443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU75", "target": "species_10065439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LU75", "target": "species_10035556" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012885", "target": "A0A3Q1LU75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ95", "target": "species_10035554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ95", "target": "species_10065443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ95", "target": "species_10065439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ95", "target": "species_10035556" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015936", "target": "A0A452DJ95" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065443", "target": "reaction_10065445" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054395", "target": "species_10054388" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054386", "target": "reaction_10054395" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054386", "target": "reaction_10065437" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070971", "target": "species_10070969" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070967", "target": "reaction_10070971" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075540", "target": "species_10070967" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075540", "target": "A0A3Q1MB70" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5246487", "target": "reaction_10070971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB70", "target": "species_10070969" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065437", "target": "species_10054390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069948", "target": "species_5164390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069948", "target": "species_5164383" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5164389", "target": "reaction_10069948" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069945", "target": "reaction_10069948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Z9", "target": "species_10069945" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048395", "target": "F1N2Z9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054382", "target": "species_975590" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054382", "target": "species_426576" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975591", "target": "reaction_10054382" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975591", "target": "reaction_10054375" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054379", "target": "reaction_10054382" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054379", "target": "reaction_10059856" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076923", "target": "species_10054379" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065441", "target": "species_10065439" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473616", "target": "reaction_10065441" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065445", "target": "species_10035554" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065445", "target": "species_2473616" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054404", "target": "species_975622" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975643", "target": "reaction_10054404" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054401", "target": "reaction_10054404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3B7", "target": "species_10054401" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048748", "target": "F1N3B7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054375", "target": "species_975590" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054375", "target": "species_426576" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041236", "target": "reaction_10054375" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041236", "target": "reaction_10041241" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041236", "target": "reaction_10041239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNQ7", "target": "species_10041236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022391", "target": "A0JNQ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJQ9", "target": "species_10041236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001012", "target": "E1BJQ9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066247", "target": "species_10054388" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066247", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066244", "target": "reaction_10066247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N678", "target": "species_10066244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042657", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042657", "target": "species_199207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_199238", "target": "reaction_10042657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_199207", "target": "reaction_10066401" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_199207", "target": "species_429605" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_199207", "target": "species_429627" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042645", "target": "reaction_10042657" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042645", "target": "reaction_10042648" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042645", "target": "reaction_10049080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LE7", "target": "species_10042645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017091", "target": "Q32LE7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN65", "target": "species_10042645" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032961", "target": "F1MN65" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066401", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066401", "target": "species_10066394" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066401", "target": "species_76577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066388", "target": "reaction_10066401" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066394", "target": "reaction_10067733" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066398", "target": "reaction_10066401" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057284", "target": "species_10066398" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067733", "target": "species_10033909" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042936", "target": "species_200671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111355", "target": "reaction_10042936" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111355", "target": "reaction_10033849" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111355", "target": "reaction_10034998" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042933", "target": "reaction_10042936" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048106", "target": "species_10042933" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081339", "target": "species_6801458" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081339", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6801458", "target": "reaction_10081349" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081336", "target": "reaction_10081339" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081336", "target": "reaction_10081349" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI11", "target": "species_10081336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006419", "target": "A0A452DI11" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNJ2", "target": "species_10081336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061329", "target": "E1BNJ2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042940", "target": "species_197965" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200716", "target": "reaction_10042940" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200716", "target": "reaction_10086763" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_197965", "target": "species_10086761" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197965", "target": "reaction_10092306" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197965", "target": "reaction_10042922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197965", "target": "reaction_10041838" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042919", "target": "reaction_10042940" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042919", "target": "reaction_10042922" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042919", "target": "reaction_10052914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035283", "target": "species_10042919" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082078", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082078", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082078", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082078", "target": "species_197969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111353", "target": "reaction_10082078" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082075", "target": "reaction_10082078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMG9", "target": "species_10082075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043693", "target": "E1BMG9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042929", "target": "species_200665" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200709", "target": "reaction_10042929" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042926", "target": "reaction_10042929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082124", "target": "species_10042926" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041840", "target": "species_111355" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041840", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73604", "target": "reaction_10041840" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041835", "target": "reaction_10041840" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041835", "target": "reaction_10041838" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010103", "target": "species_10041835" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010103", "target": "A0A140T872" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087442", "target": "species_197965" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087442", "target": "species_10086759" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086761", "target": "reaction_10087442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN9", "target": "species_10086761" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN9", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN9", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN9", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCN9", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027602", "target": "Q0VCN9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027602", "target": "species_10086759" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086759", "target": "reaction_10086763" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092306", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092306", "target": "species_73604" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092303", "target": "reaction_10092306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T872", "target": "species_10092303" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082068", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082068", "target": "species_200679" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082068", "target": "species_113600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082068", "target": "species_29376" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6808499", "target": "reaction_10082068" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082065", "target": "reaction_10082068" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG9", "target": "species_10082065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008298", "target": "E1BDG9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086763", "target": "species_10086761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042922", "target": "species_200716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041838", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041838", "target": "species_73604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081346", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081346", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081346", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081346", "target": "species_200640" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6803257", "target": "reaction_10081346" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081343", "target": "reaction_10081346" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026669", "target": "species_10081343" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076485", "target": "species_200671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076485", "target": "species_379732" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076482", "target": "reaction_10076485" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ20", "target": "species_10076482" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038244", "target": "Q3SZ20" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081349", "target": "species_5389850" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041817", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041817", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041814", "target": "reaction_10041817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKT9", "target": "species_10041814" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069099", "target": "A0A3Q1NKT9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042906", "target": "species_8938078" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042906", "target": "species_8938090" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8938083", "target": "reaction_10042906" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042903", "target": "reaction_10042906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NCV5", "target": "species_10042903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074137", "target": "A0A3Q1NCV5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088666", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088666", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088666", "target": "species_113529" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088663", "target": "reaction_10088666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR42", "target": "species_10088663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077253", "target": "A0A3Q1LR42" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086748", "target": "species_109277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086748", "target": "species_8940067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352330", "target": "reaction_10086748" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352330", "target": "reaction_10085374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352330", "target": "reaction_10086630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8940067", "target": "reaction_10086750" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036204", "target": "reaction_10086748" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036204", "target": "reaction_10086750" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036204", "target": "reaction_10036207" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036204", "target": "reaction_10036209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCG3", "target": "species_10036204" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074100", "target": "A0A3Q1MCG3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086750", "target": "species_109277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086750", "target": "species_8940077" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085374", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085374", "target": "species_8870342" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085374", "target": "species_8870343" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8870342", "target": "species_8952909" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085371", "target": "reaction_10085374" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLP3", "target": "species_10085371" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLP3", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLP3", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008097", "target": "F1MLP3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085362", "target": "species_8869353" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085362", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085362", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8869377", "target": "reaction_10085362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8869377", "target": "reaction_10085365" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085356", "target": "reaction_10085362" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085356", "target": "reaction_10085359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044763", "target": "species_10085356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085365", "target": "species_8869353" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085365", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085365", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085349", "target": "reaction_10085365" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085349", "target": "reaction_10085352" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072443", "target": "species_10085349" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081977", "target": "species_6807477" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6807473", "target": "reaction_10081977" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6807477", "target": "reaction_10081984" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081974", "target": "reaction_10081977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF13", "target": "species_10081974" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080451", "target": "A0A3Q1MF13" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071643", "target": "species_549282" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071643", "target": "species_71285" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039927", "target": "reaction_10071643" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10039927", "target": "reaction_10039930" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040069", "target": "species_10039927" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086623", "target": "species_197277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086623", "target": "species_8938282" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8938276", "target": "reaction_10086623" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086620", "target": "reaction_10086623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R6Y8", "target": "species_10086620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029045", "target": "F6R6Y8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0E5", "target": "species_10086620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084343", "target": "A0A3Q1M0E5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRP9", "target": "species_10086620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012765", "target": "F1MRP9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082143", "target": "species_6809289" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082143", "target": "species_193465" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10082140", "target": "reaction_10082143" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039965", "target": "species_10082140" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041824", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041824", "target": "species_197220" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041821", "target": "reaction_10041824" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083136", "target": "species_10041821" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041808", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041808", "target": "species_197220" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041805", "target": "reaction_10041808" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S3", "target": "species_10041805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S3", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S3", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084634", "target": "A0A3Q1N5S3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081984", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081984", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081984", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081984", "target": "species_113600" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081981", "target": "reaction_10081984" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015238", "target": "species_10081981" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088867", "target": "species_352330" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088867", "target": "species_351629" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8956473", "target": "reaction_10088867" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:90174", "target": "species_8956473" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:90171", "target": "species_8956473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10084322" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10044828" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10043986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10092214" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10092310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10080786" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351629", "target": "reaction_10065929" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088864", "target": "reaction_10088867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF84", "target": "species_10088864" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069540", "target": "A0A3Q1NF84" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049170", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049170", "target": "species_429748" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_429739", "target": "reaction_10049170" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32544", "target": "species_429739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32544", "target": "species_8876310" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049167", "target": "reaction_10049170" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049167", "target": "reaction_10049173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015315", "target": "species_10049167" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085352", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085352", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085352", "target": "species_197220" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8869365", "target": "reaction_10085352" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8869365", "target": "reaction_10085359" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085359", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085359", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085359", "target": "species_197220" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042915", "target": "species_8878981" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042915", "target": "species_200499" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_200492", "target": "reaction_10042915" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042912", "target": "reaction_10042915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD50", "target": "species_10042912" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082151", "target": "Q0VD50" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041831", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041831", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041831", "target": "species_197220" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_197238", "target": "reaction_10041831" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041828", "target": "reaction_10041831" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083204", "target": "species_10041828" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086630", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086630", "target": "species_8870342" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086630", "target": "species_8870343" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086627", "target": "reaction_10086630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073897", "target": "species_10086627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053298", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053298", "target": "species_947539" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053298", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_947561", "target": "reaction_10053298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_947496", "target": "reaction_10053298" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_947539", "target": "reaction_10053266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_947539", "target": "species_10060213" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053295", "target": "reaction_10053298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME13", "target": "species_10053295" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081310", "target": "A0A3Q1ME13" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053266", "target": "species_947575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053266", "target": "species_29432" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29432", "target": "reaction_10033681" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10053263", "target": "reaction_10053266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065375", "target": "species_10053263" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053287", "target": "species_29432" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053287", "target": "species_10053277" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053272", "target": "reaction_10053287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4L8", "target": "species_10053272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4L8", "target": "species_10053277" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070167", "target": "A1A4L8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053284", "target": "reaction_10053287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG4", "target": "species_10053284" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG4", "target": "species_10057762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG4", "target": "species_10057778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG4", "target": "species_10057790" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009149", "target": "A5PKG4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053352", "target": "species_29390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053352", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_965131", "target": "reaction_10053352" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_965131", "target": "reaction_10066619" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053345", "target": "reaction_10053352" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053345", "target": "reaction_10053348" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053345", "target": "reaction_10053350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II59", "target": "species_10053345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II59", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II59", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II59", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II59", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024203", "target": "Q0II59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066619", "target": "species_3204324" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066619", "target": "species_29408" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066616", "target": "reaction_10066619" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33722", "target": "species_10066616" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:44074", "target": "species_10066616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJG6", "target": "species_10066616" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075745", "target": "A0A3Q1LJG6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053361", "target": "species_29390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053361", "target": "species_29408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964952", "target": "reaction_10053361" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053358", "target": "reaction_10053361" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053358", "target": "reaction_10053363" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9K3", "target": "species_10053358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016263", "target": "Q5E9K3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053363", "target": "species_29390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053363", "target": "species_31633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053363", "target": "species_29408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_965146", "target": "reaction_10053363" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053348", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053348", "target": "species_965146" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_964945", "target": "reaction_10053348" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053350", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053350", "target": "species_964952" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_965053", "target": "reaction_10053350" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041753", "target": "species_29480" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041753", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196934", "target": "reaction_10041753" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29480", "target": "species_10034038" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041750", "target": "reaction_10041753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMH4", "target": "species_10041750" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085465", "target": "A0A3Q1LMH4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042799", "target": "species_196934" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_199622", "target": "reaction_10042799" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042796", "target": "reaction_10042799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E352", "target": "species_10042796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084175", "target": "A7E352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLU2", "target": "species_10042796" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027006", "target": "E1BLU2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066585", "target": "species_3159274" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066585", "target": "species_3159297" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3159260", "target": "reaction_10066585" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066582", "target": "reaction_10066585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBS4", "target": "species_10066582" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056628", "target": "A0A3Q1NBS4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066587", "target": "species_10033884" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033882", "target": "reaction_10066587" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066458", "target": "species_10066456" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066454", "target": "reaction_10066458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015993", "target": "species_10066454" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015993", "target": "E1BCN2" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3000125", "target": "reaction_10066458" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3000125", "target": "reaction_10066430" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3000125", "target": "reaction_10066882" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066456" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066428" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066438" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066519" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066442" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066448" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_3132775" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066469" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3000241", "target": "species_10066465" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3000241", "target": "reaction_10066502" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN2", "target": "species_10066456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN2", "target": "species_10066469" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN2", "target": "species_10066465" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066461", "target": "species_10066438" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066428", "target": "reaction_10066461" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSC9", "target": "species_10066428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSC9", "target": "species_10066438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSC9", "target": "species_10066442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9XSC9", "target": "species_10066448" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029446", "target": "Q9XSC9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029446", "target": "species_10066426" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066440", "target": "reaction_10066461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005777", "target": "species_10066440" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005777", "target": "A6QNY1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066438", "target": "reaction_10066444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNY1", "target": "species_10066438" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076254", "target": "species_10076247" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076254", "target": "species_10076245" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076243", "target": "reaction_10076254" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076251", "target": "reaction_10076254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071882", "target": "species_10076251" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066526", "target": "species_3000125" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066519", "target": "reaction_10066526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU6", "target": "species_10066519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU6", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU6", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU6", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU6", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027423", "target": "E1BCU6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027423", "target": "species_10066517" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066523", "target": "reaction_10066526" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066430", "target": "species_10066428" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066426", "target": "reaction_10066430" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066576", "target": "species_10066567" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066576", "target": "species_3149564" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066565", "target": "reaction_10066576" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066565", "target": "reaction_10066569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Z9", "target": "species_10066565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Z9", "target": "species_10066567" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087246", "target": "A0A3Q1M6Z9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087246", "target": "species_10066563" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3149479", "target": "species_10066565" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3149479", "target": "species_10066499" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9C8", "target": "species_10066565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9C8", "target": "species_10066567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9C8", "target": "species_10066499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022638", "target": "Q5E9C8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022638", "target": "species_10066497" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066450", "target": "species_10066448" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066442", "target": "reaction_10066450" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066448", "target": "reaction_10066473" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066569", "target": "species_10066567" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066569", "target": "species_3149479" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066473", "target": "species_3000239" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066571", "target": "species_10066565" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066563", "target": "reaction_10066571" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066499", "target": "reaction_10066571" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066444", "target": "species_10066442" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066444", "target": "species_10066440" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066574", "target": "species_10066499" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066574", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066574", "target": "species_1130611" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066497", "target": "reaction_10066574" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066497", "target": "reaction_10066502" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3149505", "target": "reaction_10066574" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066528", "target": "species_10066519" }, { "type": "product", "sub_type": "", "source": "reaction_10066528", "target": "species_3132772" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066517", "target": "reaction_10066528" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066517", "target": "reaction_10066882" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_3132775", "target": "reaction_10066528" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066882", "target": "species_10066519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066471", "target": "species_10066465" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066469", "target": "reaction_10066471" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066502", "target": "species_10066499" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066502", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042648", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042648", "target": "species_196820" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_199192", "target": "reaction_10042648" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_196820", "target": "species_429605" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_196820", "target": "species_429627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041737", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041737", "target": "species_196834" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041737", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196786", "target": "reaction_10041737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196834", "target": "reaction_10041765" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041734", "target": "reaction_10041737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP75", "target": "species_10041734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017259", "target": "A0A3S5ZP75" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041756", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041756", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196778", "target": "reaction_10041756" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041741", "target": "reaction_10041756" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041741", "target": "reaction_10041744" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072656", "target": "species_10041741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042655", "target": "species_29374" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10042652", "target": "reaction_10042655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031344", "target": "species_10042652" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041744", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041744", "target": "species_196778" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196767", "target": "reaction_10041744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041765", "target": "species_196767" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041765", "target": "species_113528" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041762", "target": "reaction_10041765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNK4", "target": "species_10041762" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076608", "target": "A0A3Q1MNK4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053048", "target": "species_10039554" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039550", "target": "reaction_10053048" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075628", "target": "species_10039550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075628", "target": "A0A3Q1MWF9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039554", "target": "reaction_10053046" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039554", "target": "reaction_10056082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039554", "target": "reaction_10090837" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10039554" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10040193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10039552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10039558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10040195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10056080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10056086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10053056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWF9", "target": "species_10056078" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053046", "target": "species_10040193" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040193", "target": "reaction_10053058" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037203", "target": "species_10037173" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037203", "target": "species_30595" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037126", "target": "reaction_10037203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQS5", "target": "species_10037126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQS5", "target": "species_10037173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023832", "target": "A6QQS5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S2", "target": "species_10037126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S2", "target": "species_10037173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029144", "target": "G5E5S2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW69", "target": "species_10037126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW69", "target": "species_10037173" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025006", "target": "F1MW69" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037171", "target": "reaction_10037203" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7E3", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7E3", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7E3", "target": "species_10037137" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071171", "target": "A0A3Q1N7E3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071171", "target": "species_10037130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ76", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ76", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ76", "target": "species_10037137" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070366", "target": "A0A3Q1MQ76" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070366", "target": "species_10037135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10037169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10036044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM0", "target": "species_10034250" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061170", "target": "E1BMM0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061170", "target": "species_10034248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10037169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10036044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10053041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBJ1", "target": "species_10034250" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011684", "target": "Q3ZBJ1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011684", "target": "species_10034244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ91", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ91", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ91", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074897", "target": "Q1JQ91" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B8", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B8", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B8", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012481", "target": "Q5E9B8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA53", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA53", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA53", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027988", "target": "Q5EA53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9L9", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9L9", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9L9", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078070", "target": "Q2T9L9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P79", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P79", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32P79", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007165", "target": "Q32P79" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZY8", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZY8", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZY8", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069267", "target": "G3MZY8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Q3", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Q3", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Q3", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002420", "target": "Q3T0Q3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWS0", "target": "species_10037171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWS0", "target": "species_10037173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWS0", "target": "species_10037169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080412", "target": "A0A3Q1MWS0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_30595", "target": "reaction_10037203" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037173", "target": "reaction_10037207" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037205", "target": "species_10037171" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037169", "target": "reaction_10037205" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037137", "target": "reaction_10037205" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086136", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086136", "target": "species_10086115" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086136", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086105", "target": "reaction_10086136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10085883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10086161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNB1", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080327", "target": "A0A3Q1MNB1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080327", "target": "A0A3Q1MPF1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10085883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10086161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF1", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10085883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2I0", "target": "species_10086161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014310", "target": "F1N2I0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10085883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21856", "target": "species_10086161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016093", "target": "P21856" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10085883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS24", "target": "species_10086161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012631", "target": "F1MS24" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086133", "target": "reaction_10086136" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5L8", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086931", "target": "A0A3Q1N5L8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK52", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082010", "target": "A0A3Q1MK52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXL8", "target": "species_10086133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009769", "target": "F1MXL8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085932", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085932", "target": "species_10085915" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085932", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085911", "target": "reaction_10085932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS9", "target": "species_10085911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS9", "target": "species_10085915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLS9", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001303", "target": "A6QLS9" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085929", "target": "reaction_10085932" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJE1", "target": "species_10085929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022733", "target": "E1BJE1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N377", "target": "species_10085929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034026", "target": "F1N377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBE4", "target": "species_10085929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073212", "target": "A0A3Q1NBE4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086097", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086097", "target": "species_10086090" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086097", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086086", "target": "reaction_10086097" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DC2", "target": "species_10086086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DC2", "target": "species_10086090" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DC2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DC2", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075871", "target": "Q08DC2" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086094", "target": "reaction_10086097" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013748", "target": "species_10086094" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086209", "target": "species_10086196" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086209", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086209", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086188", "target": "reaction_10086209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7D3", "target": "species_10086188" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7D3", "target": "species_10086196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7D3", "target": "species_10083763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7D3", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024288", "target": "G3X7D3" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086206", "target": "reaction_10086209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUN3", "target": "species_10086206" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069720", "target": "A0A3Q1MUN3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ87", "target": "species_10086206" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027075", "target": "F1MQ87" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086019", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086019", "target": "species_10086012" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086019", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086008", "target": "reaction_10086019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG1", "target": "species_10086008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG1", "target": "species_10086012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG1", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG1", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023671", "target": "Q3ZBG1" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086016", "target": "reaction_10086019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067401", "target": "species_10086016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085988", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085988", "target": "species_10085983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085988", "target": "species_10085883" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085979", "target": "reaction_10085988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPX8", "target": "species_10085979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPX8", "target": "species_10085983" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013671", "target": "A6QPX8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085985", "target": "reaction_10085988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCL3", "target": "species_10085985" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087265", "target": "A0A3Q1MCL3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086054", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086054", "target": "species_10085883" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086054", "target": "species_10086041" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086037", "target": "reaction_10086054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPP1", "target": "species_10086037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPP1", "target": "species_10086041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025807", "target": "F1MPP1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086051", "target": "reaction_10086054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y7", "target": "species_10086051" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075635", "target": "A0A3Q1M4Y7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M373", "target": "species_10086051" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078087", "target": "A0A3Q1M373" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086182", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086182", "target": "species_10085883" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086182", "target": "species_10086169" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086161", "target": "reaction_10086182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA60", "target": "species_10086161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA60", "target": "species_10086169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012905", "target": "E1BA60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9C0", "target": "species_10086161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9C0", "target": "species_10086169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020971", "target": "E1B9C0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086179", "target": "reaction_10086182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7M9", "target": "species_10086179" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056415", "target": "E1B7M9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N720", "target": "species_10086179" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071404", "target": "A0A3Q1N720" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048567", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048567", "target": "species_83910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048564", "target": "reaction_10048567" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB11", "target": "species_10048564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002235", "target": "E1BB11" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU00", "target": "species_10048564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006073", "target": "F1MU00" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Y0", "target": "species_10048564" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054801", "target": "E1B8Y0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048550", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048550", "target": "species_425971" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_425978", "target": "reaction_10048550" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048547", "target": "reaction_10048550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073706", "target": "species_10048547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058841", "target": "species_426639" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058841", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498733", "target": "reaction_10058841" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058838", "target": "reaction_10058841" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058838", "target": "reaction_10058874" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068283", "target": "species_10058838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059000", "target": "species_1498733" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059000", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058905", "target": "reaction_10059000" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058905", "target": "reaction_10058908" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058905", "target": "reaction_10058945" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058905", "target": "reaction_10059018" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059851", "target": "species_1602420" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059851", "target": "species_1602366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426658", "target": "reaction_10059851" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426658", "target": "reaction_10060473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426658", "target": "reaction_10060461" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058874", "target": "species_426639" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058874", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498737", "target": "reaction_10058874" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058975", "target": "species_1498733" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058975", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058972", "target": "reaction_10058975" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059026", "target": "species_1498737" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059026", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059023", "target": "reaction_10059026" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048682", "target": "species_10035252" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035250", "target": "reaction_10048682" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035235", "target": "reaction_10048682" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048717", "target": "species_427497" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048717", "target": "species_10044309" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048717", "target": "species_427498" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048700", "target": "reaction_10048717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427523", "target": "reaction_10048717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427523", "target": "reaction_10075037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427523", "target": "reaction_10077108" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427523", "target": "reaction_10091096" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044309", "target": "reaction_10048720" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044309", "target": "reaction_10044361" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048714", "target": "reaction_10048717" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048714", "target": "reaction_10048720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJI1", "target": "species_10048714" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039795", "target": "E1BJI1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQB8", "target": "species_10048714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQB8", "target": "species_10067991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQB8", "target": "species_10091093" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018630", "target": "F1MQB8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018630", "target": "species_10048710" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048720", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048720", "target": "species_10048712" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044361", "target": "species_10044359" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044357", "target": "reaction_10044361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ25", "target": "species_10044327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010324", "target": "Q3SZ25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK4", "target": "species_10044327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084115", "target": "A0A3Q1MSK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M792", "target": "species_10044327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077887", "target": "A0A3Q1M792" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10068697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10044327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHL3", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007758", "target": "Q3MHL3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPJ7", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPJ7", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPJ7", "target": "species_10044378" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083404", "target": "A0A3Q1LPJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Y2", "target": "species_10044357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Y2", "target": "species_10044359" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Y2", "target": "species_10044378" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022557", "target": "F1N6Y2" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044359", "target": "reaction_10044381" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044381", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044381", "target": "species_10044378" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044333", "target": "species_10044331" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044307", "target": "reaction_10044333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9H4", "target": "species_10044307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9H4", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9H4", "target": "species_10044387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9H4", "target": "species_10070518" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086443", "target": "A0A3Q1M9H4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086443", "target": "species_10044297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVT5", "target": "species_10044307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVT5", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVT5", "target": "species_10044387" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069734", "target": "A0A3Q1LVT5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII9", "target": "species_10044307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII9", "target": "species_10044331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII9", "target": "species_10044387" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003549", "target": "A0A452DII9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044329", "target": "reaction_10044333" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044331", "target": "reaction_10044390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044390", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044390", "target": "species_10044387" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070700", "target": "species_10036706" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070700", "target": "species_5221065" }, { "type": "reactant", "sub_type": "", "source": "species_5221062", "target": "reaction_10070700" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036698", "target": "reaction_10070700" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036698", "target": "reaction_10070702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072242", "target": "species_10036698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072242", "target": "A0A3Q1LSS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSS4", "target": "species_10036706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSS4", "target": "species_10036713" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSS4", "target": "species_10036702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSS4", "target": "species_10036740" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070702", "target": "species_10036706" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070702", "target": "species_5221064" }, { "type": "reactant", "sub_type": "", "source": "species_5220996", "target": "reaction_10070702" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071065", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071065", "target": "species_10071014" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10071065" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10068569" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10067596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10078369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10074453" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10087900" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10083077" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10072550" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113560", "target": "reaction_10091089" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071062", "target": "reaction_10071065" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJQ1", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017097", "target": "A5PJQ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6X6", "target": "species_10071062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6X6", "target": "species_10074717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072070", "target": "E1B6X6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKX3", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009771", "target": "E1BKX3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX61", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011734", "target": "F1MX61" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M384", "target": "species_10071062" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M384", "target": "species_10051335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M384", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M384", "target": "species_10074717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070441", "target": "A0A3Q1M384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QHI8", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019351", "target": "F6QHI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQD6", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043676", "target": "Q1JQD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB6", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004611", "target": "Q32LB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUD5", "target": "species_10071062" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056158", "target": "F1MUD5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065336", "target": "species_10065334" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065332", "target": "reaction_10065336" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065308", "target": "reaction_10065336" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075583", "target": "species_10065308" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075583", "target": "A0A3Q1LJU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJU9", "target": "species_10065334" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065435", "target": "species_10065433" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065431", "target": "reaction_10065435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLT0", "target": "species_10065431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLT0", "target": "species_10065433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060945", "target": "F1MLT0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X7", "target": "species_10065431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8X7", "target": "species_10065433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001312", "target": "E1B8X7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT44", "target": "species_10065431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MT44", "target": "species_10065433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005807", "target": "F1MT44" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064435", "target": "species_10064433" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064421", "target": "reaction_10064435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN12", "target": "species_10064421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN12", "target": "species_10064433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070645", "target": "A0A3Q1MN12" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLS8", "target": "species_10064421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLS8", "target": "species_10064433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015049", "target": "E1BLS8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064431", "target": "reaction_10064435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P55918", "target": "species_10064431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P55918", "target": "species_10064433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008130", "target": "P55918" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA98", "target": "species_10064431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA98", "target": "species_10064433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022877", "target": "Q5EA98" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063839", "target": "species_10063837" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063825", "target": "reaction_10063839" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064437", "target": "species_10063809" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10059655", "target": "reaction_10064437" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067346", "target": "species_83910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067343", "target": "reaction_10067346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNX9", "target": "species_10067343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008077", "target": "E1BNX9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0Y5", "target": "species_10067343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075032", "target": "A0A3Q1M0Y5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092050", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092047", "target": "reaction_10092050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E522", "target": "species_10092047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E522", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002668", "target": "G5E522" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067330", "target": "reaction_10092050" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067330", "target": "reaction_10067332" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067330", "target": "reaction_10091808" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067330", "target": "reaction_10072346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10067330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10091797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10091803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10072344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10070680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10091777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10070686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10091781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10067320" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10072328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10072338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10067318" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10070524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10070526" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA8", "target": "species_10070529" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024511", "target": "E1BKA8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024511", "target": "species_10070522" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024511", "target": "species_10091771" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024511", "target": "species_10091769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024511", "target": "species_10091786" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10067330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10072344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10070680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10091777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10070686" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10091781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10072328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGC6", "target": "species_10072338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082389", "target": "E1BGC6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082389", "target": "species_10070678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067332", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067306", "target": "reaction_10067332" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY82", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065500", "target": "G3MY82" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065500", "target": "species_10052920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPC8", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019509", "target": "E1BPC8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2S2", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066065", "target": "G3N2S2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA32", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003922", "target": "Q5EA32" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10067306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M893", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074148", "target": "A0A3Q1M893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPF0", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044081", "target": "F1MPF0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79100", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065392", "target": "P79100" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAN3", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033438", "target": "E1BAN3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N232", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068680", "target": "F1N232" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDG0", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022589", "target": "E1BDG0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCP0", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085000", "target": "E1BCP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Y9", "target": "species_10067306" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002485", "target": "E1B6Y9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039604", "target": "species_113529" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039233", "target": "reaction_10039604" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039233", "target": "reaction_10039242" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BME0", "target": "species_10039233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BME0", "target": "species_10039235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BME0", "target": "species_10039237" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021691", "target": "E1BME0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIJ0", "target": "species_10039233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIJ0", "target": "species_10039235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIJ0", "target": "species_10039237" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021633", "target": "Q2KIJ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZI5", "target": "species_10039233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZI5", "target": "species_10039235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZI5", "target": "species_10039237" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004810", "target": "Q3SZI5" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_170037", "target": "reaction_10039604" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039240", "target": "species_10039237" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039235", "target": "reaction_10039240" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166216", "target": "species_10039235" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166216", "target": "species_10039237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039237", "target": "reaction_10039254" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039242", "target": "species_10039235" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_166213", "target": "reaction_10039242" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039254", "target": "species_166216" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039254", "target": "species_10039233" }, { "type": "product", "sub_type": "", "source": "reaction_10073400", "target": "species_10066894" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073400", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073400", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073400", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10073398", "target": "reaction_10073400" }, { "type": "reactant", "sub_type": "", "source": "species_10066894", "target": "reaction_10069754" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069751", "target": "reaction_10073400" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069751", "target": "reaction_10069754" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069751", "target": "reaction_10073404" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069751", "target": "reaction_10073406" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025492", "target": "species_10069751" }, { "type": "product", "sub_type": "", "source": "reaction_10066651", "target": "species_10066644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066651", "target": "species_29478" }, { "type": "reactant", "sub_type": "", "source": "species_10066642", "target": "reaction_10066651" }, { "type": "reactant", "sub_type": "", "source": "species_10066642", "target": "reaction_10072725" }, { "type": "reactant", "sub_type": "", "source": "species_10066644", "target": "reaction_10069937" }, { "type": "reactant", "sub_type": "", "source": "species_10066644", "target": "reaction_10072755" }, { "type": "reactant", "sub_type": "", "source": "species_10066644", "target": "reaction_10069846" }, { "type": "reactant", "sub_type": "", "source": "species_10066644", "target": "reaction_10072790" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066648", "target": "reaction_10066651" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066648", "target": "reaction_10073402" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076721", "target": "species_10066648" }, { "type": "product", "sub_type": "", "source": "reaction_10073402", "target": "species_10066642" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073402", "target": "species_29478" }, { "type": "reactant", "sub_type": "", "source": "species_10069756", "target": "reaction_10073402" }, { "type": "reactant", "sub_type": "", "source": "species_10069756", "target": "reaction_10069769" }, { "type": "reactant", "sub_type": "", "source": "species_10069756", "target": "reaction_10070962" }, { "type": "product", "sub_type": "", "source": "reaction_10069754", "target": "species_10066644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069754", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069754", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069754", "target": "species_159939" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073404", "target": "species_10035060" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073404", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073404", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073404", "target": "species_159939" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070273", "target": "reaction_10073404" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070273", "target": "reaction_10073416" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035060", "target": "reaction_10067596" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035060", "target": "reaction_10070282" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073406", "target": "species_10070273" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073406", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073406", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073406", "target": "species_159939" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070419", "target": "reaction_10073406" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070419", "target": "reaction_10070520" }, { "type": "product", "sub_type": "", "source": "reaction_10069747", "target": "species_10066644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069747", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069747", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069747", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10069723", "target": "reaction_10069747" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069744", "target": "reaction_10069747" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069744", "target": "reaction_10073382" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080313", "target": "species_10069744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073394", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073394", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073394", "target": "species_159939" }, { "type": "product", "sub_type": "", "source": "reaction_10073394", "target": "species_10069721" }, { "type": "reactant", "sub_type": "", "source": "species_10069811", "target": "reaction_10073394" }, { "type": "reactant", "sub_type": "", "source": "species_10069721", "target": "reaction_10069740" }, { "type": "reactant", "sub_type": "", "source": "species_10069721", "target": "reaction_10073382" }, { "type": "reactant", "sub_type": "", "source": "species_10069721", "target": "reaction_10069838" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069737", "target": "reaction_10073394" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069737", "target": "reaction_10069740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT70", "target": "species_10069737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078784", "target": "A0A3Q1MT70" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB12", "target": "species_10069737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002234", "target": "E1BB12" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL5", "target": "species_10069737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL5", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL5", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL5", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL5", "target": "species_10074546" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002687", "target": "E1BPL5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002687", "target": "species_10069716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI23", "target": "species_10069737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070121", "target": "A0A3Q1MI23" }, { "type": "product", "sub_type": "", "source": "reaction_10073396", "target": "species_10069777" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073396", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073396", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073396", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10072792", "target": "reaction_10073396" }, { "type": "reactant", "sub_type": "", "source": "species_10069777", "target": "reaction_10069796" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069793", "target": "reaction_10073396" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069793", "target": "reaction_10069796" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2E9", "target": "species_10069793" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063826", "target": "G3N2E9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N346", "target": "species_10069793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N346", "target": "species_10066776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063022", "target": "G3N346" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063022", "target": "species_10066774" }, { "type": "product", "sub_type": "", "source": "reaction_10069719", "target": "species_10066644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069719", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069719", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069719", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10069712", "target": "reaction_10069719" }, { "type": "reactant", "sub_type": "", "source": "species_10069712", "target": "reaction_10072752" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069716", "target": "reaction_10069719" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069716", "target": "reaction_10073380" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069716", "target": "reaction_10074679" }, { "type": "product", "sub_type": "", "source": "reaction_10069769", "target": "species_10066642" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069769", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069769", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069769", "target": "species_159939" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069766", "target": "reaction_10069769" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069766", "target": "reaction_10073384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ57", "target": "species_10069766" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071767", "target": "A0A3Q1MZ57" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR2", "target": "species_10069766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUR2", "target": "species_10084933" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028871", "target": "F1MUR2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028871", "target": "species_10069764" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073384", "target": "species_29478" }, { "type": "product", "sub_type": "", "source": "reaction_10073384", "target": "species_10069756" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073384", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073384", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10070949", "target": "reaction_10073384" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069740", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069740", "target": "species_159942" }, { "type": "product", "sub_type": "", "source": "reaction_10069740", "target": "species_10069723" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069740", "target": "species_159939" }, { "type": "product", "sub_type": "", "source": "reaction_10073380", "target": "species_10069712" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073380", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073380", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073380", "target": "species_159939" }, { "type": "reactant", "sub_type": "", "source": "species_10072735", "target": "reaction_10073380" }, { "type": "reactant", "sub_type": "", "source": "species_10072735", "target": "reaction_10072750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069796", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069796", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069796", "target": "species_159939" }, { "type": "product", "sub_type": "", "source": "reaction_10069796", "target": "species_10069785" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073382", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073382", "target": "species_159942" }, { "type": "product", "sub_type": "", "source": "reaction_10073382", "target": "species_10069723" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073382", "target": "species_159939" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069937", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10069937", "target": "species_10066642" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069934", "target": "reaction_10069937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT0", "target": "species_10069934" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004658", "target": "F1MUT0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU6", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012183", "target": "Q2NKU6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX2", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070677", "target": "E1BLX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10069934" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10072722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHA1", "target": "species_10086531" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024084", "target": "F1MHA1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072752", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072752", "target": "species_10072735" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069843", "target": "reaction_10072752" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069843", "target": "reaction_10069846" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034204", "target": "species_10069843" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072755", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072755", "target": "species_10069785" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044337", "target": "reaction_10072755" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069939", "target": "species_10069836" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069830", "target": "reaction_10069939" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000107", "target": "species_10069830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000107", "target": "E1BKH5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069834", "target": "reaction_10069939" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086218", "target": "species_10069834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086218", "target": "A0A3Q1M7L9" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069836", "target": "reaction_10069838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7L9", "target": "species_10069836" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKH5", "target": "species_10069836" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070962", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070962", "target": "species_10070949" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070959", "target": "reaction_10070962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5C5", "target": "species_10070959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5C5", "target": "species_10072722" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047138", "target": "Q0P5C5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X834", "target": "species_10070959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056084", "target": "G3X834" }, { "type": "inhibitor", "sub_type": "", "source": "species_10070404", "target": "reaction_10070962" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072725", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072725", "target": "species_10069756" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072722", "target": "reaction_10072725" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072788", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072788", "target": "species_10072786" }, { "type": "reactant", "sub_type": "", "source": "species_10072771", "target": "reaction_10072788" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072775", "target": "reaction_10072788" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072775", "target": "reaction_10072790" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072775", "target": "reaction_10072778" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082174", "target": "species_10072775" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072823", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072823", "target": "species_10072821" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072800", "target": "reaction_10072823" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072810", "target": "reaction_10072823" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072810", "target": "reaction_10072813" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6A7", "target": "species_10072810" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075432", "target": "A0A3Q1M6A7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MID6", "target": "species_10072810" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070396", "target": "A0A3Q1MID6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069846", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10069846", "target": "species_10069712" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072790", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072790", "target": "species_10072763" }, { "type": "reactant", "sub_type": "", "source": "species_10072763", "target": "reaction_10072778" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072778", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072778", "target": "species_10072771" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072813", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072813", "target": "species_10072800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064889", "target": "reaction_10072813" }, { "type": "product", "sub_type": "", "source": "reaction_10072655", "target": "species_10072642" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072655", "target": "species_71285" }, { "type": "reactant", "sub_type": "", "source": "species_10072636", "target": "reaction_10072655" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072652", "target": "reaction_10072655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTF1", "target": "species_10072652" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025245", "target": "F1MTF1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069838", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10069838", "target": "species_10069811" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069825", "target": "reaction_10069838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6Y5", "target": "species_10069825" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022553", "target": "F1N6Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXG0", "target": "species_10069825" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009641", "target": "F1MXG0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ38", "target": "species_10069825" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013472", "target": "A0A452DJ38" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072750", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10072750", "target": "species_10072743" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072747", "target": "reaction_10072750" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084416", "target": "species_10072747" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068699", "target": "species_10068658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068699", "target": "species_5566518" }, { "type": "reactant", "sub_type": "", "source": "species_10068652", "target": "reaction_10068699" }, { "type": "reactant", "sub_type": "", "source": "species_10068652", "target": "reaction_10068844" }, { "type": "reactant", "sub_type": "", "source": "species_10068652", "target": "reaction_10068725" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068694", "target": "reaction_10068699" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068694", "target": "reaction_10091745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMC8", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMC8", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063281", "target": "A0A3Q1MMC8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B806", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B806", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020692", "target": "E1B806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC01", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC01", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075111", "target": "Q0VC01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC43", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC43", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075576", "target": "A0A3Q1MC43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE0", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZE0", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023526", "target": "Q1LZE0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK1", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK1", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025155", "target": "E1BGK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFL5", "target": "species_10068694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFL5", "target": "species_10068697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005222", "target": "F1MFL5" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10068697", "target": "reaction_10068699" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068844", "target": "species_10068658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068844", "target": "species_5566518" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044720", "target": "reaction_10068844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070733", "target": "species_10044720" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091745", "target": "species_10068697" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9679795", "target": "reaction_10091745" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068725", "target": "species_10068658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068725", "target": "species_5566518" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068722", "target": "reaction_10068725" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:57627", "target": "species_10068722" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068569", "target": "species_2485002" }, { "type": "product", "sub_type": "", "source": "reaction_10068569", "target": "species_10068566" }, { "type": "reactant", "sub_type": "", "source": "species_10068132", "target": "reaction_10068569" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067596", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067596", "target": "species_10067575" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067593", "target": "reaction_10067596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP98", "target": "species_10067593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013893", "target": "F1MP98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRF9", "target": "species_10067593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000991", "target": "F1MRF9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFW0", "target": "species_10067593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030541", "target": "E1BFW0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071886", "target": "species_10071884" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071878", "target": "reaction_10071886" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071882", "target": "reaction_10071886" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013131", "target": "species_10071882" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013131", "target": "F1MTX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTX0", "target": "species_10071884" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070409", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070409", "target": "species_10070404" }, { "type": "reactant", "sub_type": "", "source": "species_10070394", "target": "reaction_10070409" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070406", "target": "reaction_10070409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQR4", "target": "species_10070406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQR4", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQR4", "target": "species_10047805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066577", "target": "A0A3Q1LQR4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066577", "target": "species_10047781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10070406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10070279" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9L5", "target": "species_10086499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009750", "target": "Q5E9L5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009750", "target": "species_10070277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070377", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070377", "target": "species_10070374" }, { "type": "reactant", "sub_type": "", "source": "species_10070328", "target": "reaction_10070377" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10070277", "target": "reaction_10070377" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10070277", "target": "reaction_10070896" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070520", "target": "species_10070518" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044297", "target": "reaction_10070520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073416", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073416", "target": "species_10073414" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070279", "target": "reaction_10073416" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070279", "target": "reaction_10070282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR38", "target": "species_10070279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068896", "target": "A0A3Q1MR38" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068896", "target": "species_10066655" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070392", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070392", "target": "species_10070389" }, { "type": "reactant", "sub_type": "", "source": "species_10070379", "target": "reaction_10070392" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047781", "target": "reaction_10070392" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047781", "target": "reaction_10070757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070282", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070282", "target": "species_10070273" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070896", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070896", "target": "species_10070894" }, { "type": "reactant", "sub_type": "", "source": "species_10070848", "target": "reaction_10070896" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070757", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070757", "target": "species_10070755" }, { "type": "reactant", "sub_type": "", "source": "species_10070745", "target": "reaction_10070757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070516", "target": "species_77502" }, { "type": "product", "sub_type": "", "source": "reaction_10070516", "target": "species_10070513" }, { "type": "reactant", "sub_type": "", "source": "species_10070467", "target": "reaction_10070516" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066655", "target": "reaction_10070516" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056383", "target": "species_29382" }, { "type": "product", "sub_type": "", "source": "reaction_10056383", "target": "species_1183191" }, { "type": "reactant", "sub_type": "", "source": "species_1183111", "target": "reaction_10056383" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056380", "target": "reaction_10056383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLC1", "target": "species_10056380" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015977", "target": "A6QLC1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N048", "target": "species_10056380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N048", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N048", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004411", "target": "F1N048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD46", "target": "species_10056380" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015978", "target": "E1BD46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN3", "target": "species_10056380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN3", "target": "species_10066963" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015991", "target": "E1BCN3" }, { "type": "product", "sub_type": "", "source": "reaction_10066966", "target": "species_10066951" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066966", "target": "species_76230" }, { "type": "reactant", "sub_type": "", "source": "species_10066920", "target": "reaction_10066966" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066963", "target": "reaction_10066966" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092108", "target": "species_10051733" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092108", "target": "species_10055212" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092108", "target": "species_10055148" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092108", "target": "species_10055146" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092108", "target": "species_10055162" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092108", "target": "species_10092105" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092095", "target": "reaction_10092108" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092091", "target": "reaction_10092108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35833", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35833", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35833", "target": "species_10092255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028610", "target": "P35833" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYA3", "target": "species_10092091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYA3", "target": "species_10092105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYA3", "target": "species_10092255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072313", "target": "A0A3Q1MYA3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092105", "target": "reaction_10092257" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092257", "target": "species_10092255" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073690", "target": "species_10073687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073673", "target": "reaction_10073690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10073696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10071979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10071971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL08", "target": "species_10071973" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009316", "target": "E1BL08" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009316", "target": "species_10047524" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009316", "target": "species_10073705" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009316", "target": "species_10047527" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10073623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10074304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTC1", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009960", "target": "F1MTC1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009960", "target": "species_10073609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10074304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP0", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011745", "target": "E1BIP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073597" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX43", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045584", "target": "F1MX43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY0", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY0", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY0", "target": "species_10073603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY0", "target": "species_10073605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY0", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081383", "target": "A0A3Q1LHY0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081383", "target": "species_10073601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJD0", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJD0", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJD0", "target": "species_10073637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJD0", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJD0", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037660", "target": "F1MJD0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037660", "target": "species_10073629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10074326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10074338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073635" }, { "type": "complex_component", "sub_type": "protein_component", "source": "B0LKN7", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065347", "target": "B0LKN7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ46", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020355", "target": "A6QQ46" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020355", "target": "species_10073643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q06600", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000018", "target": "Q06600" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK50", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027554", "target": "E1BK50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10074276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10074278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073671" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0K4", "target": "species_10073696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045141", "target": "F1N0K4" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073687", "target": "reaction_10073699" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074280", "target": "species_10074278" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074276", "target": "reaction_10074280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF06", "target": "species_10074276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF06", "target": "species_10074278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF06", "target": "species_10076235" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036452", "target": "E1BF06" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036452", "target": "species_10074274" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074270", "target": "reaction_10074280" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028109", "target": "species_10074270" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028109", "target": "A6QPW7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPW7", "target": "species_10074278" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074266", "target": "species_10074264" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074262", "target": "reaction_10074266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064406", "target": "species_10074262" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064406", "target": "Q08DT5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074258", "target": "reaction_10074266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079425", "target": "species_10074258" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079425", "target": "A0A3Q1M9X1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9X1", "target": "species_10074264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DT5", "target": "species_10074264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076237", "target": "species_10076235" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074274", "target": "reaction_10076237" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076233", "target": "reaction_10076237" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085571", "target": "species_10076233" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085571", "target": "A0A3Q1LIC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIC4", "target": "species_10076235" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073765", "target": "species_10073763" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073621", "target": "reaction_10073765" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073621", "target": "reaction_10074306" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073761", "target": "reaction_10073765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009759", "target": "species_10073761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009759", "target": "A5D7R1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7R1", "target": "species_10073763" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076165", "target": "species_10076163" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076161", "target": "reaction_10076165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY4", "target": "species_10076161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY4", "target": "species_10076163" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003763", "target": "E1BGY4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076155", "target": "reaction_10076165" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066801", "target": "species_10076155" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066801", "target": "A0A3Q1M5M3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5M3", "target": "species_10076163" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074340", "target": "species_10074338" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074326", "target": "reaction_10074340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBM0", "target": "species_10074326" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBM0", "target": "species_10074338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBM0", "target": "species_10050304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000141", "target": "Q3ZBM0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000141", "target": "species_10050382" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000141", "target": "species_10050261" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074336", "target": "reaction_10074340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU29", "target": "species_10074336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU29", "target": "species_10074338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020341", "target": "F1MU29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M673", "target": "species_10074336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M673", "target": "species_10074338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085489", "target": "A0A3Q1M673" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074312", "target": "species_10073671" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073669", "target": "reaction_10074312" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073585", "target": "reaction_10074312" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073585", "target": "reaction_10074314" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073585", "target": "reaction_10074316" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073585", "target": "reaction_10074318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074314", "target": "species_10073625" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073623", "target": "reaction_10074314" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073757", "target": "species_10073603" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073601", "target": "reaction_10073757" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073597", "target": "reaction_10073757" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073603", "target": "reaction_10074318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074316", "target": "species_10073639" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073637", "target": "reaction_10074316" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074318", "target": "species_10073605" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074320", "target": "species_10073637" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073635", "target": "reaction_10074320" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073629", "target": "reaction_10074320" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074306", "target": "species_10074304" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073609", "target": "reaction_10074306" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073609", "target": "reaction_10074310" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074304", "target": "reaction_10074310" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074308", "target": "species_10073669" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073667", "target": "reaction_10074308" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073643", "target": "reaction_10074308" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074310", "target": "species_10073623" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073699", "target": "species_10073696" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071948", "target": "species_10047524" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047524", "target": "reaction_10071948" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047524", "target": "reaction_10073708" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047524", "target": "reaction_10047530" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073708", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10073708", "target": "species_10073705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071982", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071982", "target": "species_10071971" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071979", "target": "reaction_10071982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB7", "target": "species_10071979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB7", "target": "species_10071971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB7", "target": "species_10071991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB7", "target": "species_10072028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB7", "target": "species_10071973" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007904", "target": "A7MBB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBB0", "target": "species_10071979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBB0", "target": "species_10071971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBB0", "target": "species_10071991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBB0", "target": "species_10072028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBB0", "target": "species_10071973" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055496", "target": "F1MBB0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071971", "target": "reaction_10071975" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072030", "target": "species_10072028" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071991", "target": "reaction_10072030" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071975", "target": "species_10071973" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056243", "target": "reaction_10071975" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056243", "target": "reaction_10066489" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057834", "target": "species_10054522" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054520", "target": "reaction_10057834" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10056333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10054777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10056255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZG1", "target": "species_10056265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10056333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01239", "target": "species_10054789" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020313", "target": "P01239" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054509" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054507" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10056333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M283", "target": "species_10054789" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082398", "target": "A0A3Q1M283" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10054522", "target": "reaction_10054524" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054522", "target": "reaction_10056335" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054524", "target": "species_10054511" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054501", "target": "reaction_10054524" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054509", "target": "reaction_10054524" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054511", "target": "reaction_10060412" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054511", "target": "reaction_10057836" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054511", "target": "reaction_10054791" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060412", "target": "species_10054511" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057836", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057836", "target": "species_10054520" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057823", "target": "species_10054509" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054507", "target": "reaction_10057823" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056335", "target": "species_10043873" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056335", "target": "species_10056333" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054791", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054791", "target": "species_10054785" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054789", "target": "reaction_10054791" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054779", "target": "species_10054777" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056268", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056268", "target": "species_10056265" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056255", "target": "reaction_10056268" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090844", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090844", "target": "species_10036552" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084303", "target": "reaction_10090844" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092151" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092040" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092139" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092143" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092126" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092147" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092183" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092137" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092043" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036552", "target": "reaction_10092133" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10090842", "target": "reaction_10090844" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10090840", "target": "reaction_10090844" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092151", "target": "species_10092149" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037584", "target": "reaction_10092151" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037584", "target": "reaction_10065642" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037584", "target": "reaction_10072392" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037584", "target": "reaction_10037588" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092159", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092159", "target": "species_10092156" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092135", "target": "reaction_10092159" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077790", "target": "species_10077788" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036540", "target": "reaction_10077790" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077786", "target": "reaction_10077790" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077786", "target": "reaction_10084305" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077788", "target": "reaction_10084305" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084305", "target": "species_10084303" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092040", "target": "species_10092037" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092040", "target": "species_29372" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10080697", "target": "reaction_10092040" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081330", "target": "species_10080697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081330", "target": "A0A3Q1M6K1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092139", "target": "species_10092112" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055924", "target": "reaction_10092139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079236", "target": "species_10055924" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079236", "target": "A0A3Q1MQG1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092112", "target": "reaction_10092126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQG1", "target": "species_10092112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQG1", "target": "species_10055926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQG1", "target": "species_10055931" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092173", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092173", "target": "species_10092170" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092110", "target": "reaction_10092173" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092141", "target": "species_10092118" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092116", "target": "reaction_10092141" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081400", "target": "species_10092116" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081400", "target": "A0A3Q1MHK8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092118", "target": "reaction_10092126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHK8", "target": "species_10092118" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092143", "target": "species_10092124" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092122", "target": "reaction_10092143" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026137", "target": "species_10092122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026137", "target": "Q5BIM7" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092124", "target": "reaction_10092126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5BIM7", "target": "species_10092124" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092126", "target": "species_10092110" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092147", "target": "species_10092145" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10087926", "target": "reaction_10092147" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092195", "target": "species_10092193" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092178", "target": "reaction_10092195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092183", "target": "species_10092178" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092180", "target": "reaction_10092183" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092137", "target": "species_10092135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092043", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092043", "target": "species_10083560" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040499", "target": "reaction_10092043" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040499", "target": "reaction_10040503" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092033", "target": "species_10065275" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036565", "target": "reaction_10092033" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092133", "target": "species_10092131" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046947", "target": "reaction_10092133" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046947", "target": "reaction_10046951" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020161", "target": "species_10046947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020161", "target": "E1BKA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10092131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10046949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA6", "target": "species_10066099" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092165", "target": "species_10092163" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092161", "target": "reaction_10092165" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090916", "target": "species_10074033" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036554", "target": "reaction_10090916" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074033", "target": "reaction_10090919" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090919", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090919", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052217", "target": "species_10052194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052217", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052144", "target": "reaction_10052217" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052144", "target": "reaction_10052147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04790", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029080", "target": "Q04790" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7E8", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053863", "target": "E1B7E8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDZ1", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030158", "target": "E1BDZ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6A7", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054467", "target": "F1N6A7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMI8", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073168", "target": "A0A3Q1MMI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH9", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064849", "target": "G3MYH9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPD3", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066449", "target": "A0A3Q1LPD3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10055943" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10055948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ20", "target": "species_10052227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085216", "target": "A0A3Q1LZ20" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052194", "target": "reaction_10055946" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052194", "target": "reaction_10052196" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052347", "target": "species_10052345" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052187", "target": "reaction_10052347" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052187", "target": "reaction_10052189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DC4", "target": "species_10052187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DC4", "target": "species_10052169" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DC4", "target": "species_10052181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036455", "target": "Q58DC4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036455", "target": "species_10052163" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052189", "target": "species_10052181" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052169", "target": "reaction_10052189" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055946", "target": "species_10055943" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055946", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055955", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055955", "target": "species_10055948" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052222", "target": "reaction_10055955" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052222", "target": "reaction_10052233" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055948", "target": "reaction_10055958" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055958", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055958", "target": "species_10052206" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052206", "target": "reaction_10052229" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052159", "target": "species_10052157" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052140", "target": "reaction_10052159" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052153", "target": "reaction_10052159" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052157", "target": "reaction_10052236" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070719", "target": "species_10070717" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070711", "target": "reaction_10070719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5H027", "target": "species_10070711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5H027", "target": "species_10070717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5H027", "target": "species_10089693" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5H027", "target": "species_10089347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044248", "target": "A5H027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044248", "target": "species_10089345" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070715", "target": "reaction_10070719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048747", "target": "species_10070715" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048747", "target": "A4IFE6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048747", "target": "species_10089343" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFE6", "target": "species_10070717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFE6", "target": "species_10089347" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052147", "target": "species_10051766" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052147", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052210", "target": "species_10052206" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052204", "target": "reaction_10052210" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052200", "target": "reaction_10052210" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052200", "target": "reaction_10091725" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10052208", "target": "reaction_10052210" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052213", "target": "species_10052169" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052167", "target": "reaction_10052213" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052163", "target": "reaction_10052213" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052233", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052233", "target": "species_10052153" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091725", "target": "species_10052208" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9678619", "target": "reaction_10091725" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052236", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052236", "target": "species_10052144" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052229", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052229", "target": "species_10052222" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10052227", "target": "reaction_10052229" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052196", "target": "species_10052167" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052196", "target": "species_10052153" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056297", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056297", "target": "species_10056295" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056297", "target": "species_10056276" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056297", "target": "species_10053116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056297", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056278", "target": "reaction_10056297" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056278", "target": "reaction_10056315" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056278", "target": "reaction_10056283" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056278", "target": "reaction_10060732" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056278", "target": "reaction_10056287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10060728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10056270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10053118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10053120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02741", "target": "species_10072874" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019573", "target": "O02741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019573", "target": "species_10072880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10056278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10060728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10056270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10053118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII5", "target": "species_10053120" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017267", "target": "A0A452DII5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017267", "target": "species_10053116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA3", "target": "species_10056278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA3", "target": "species_10056276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA3", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VEA3", "target": "species_10060728" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008822", "target": "A2VEA3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10056278" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10056276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10060728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10053118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPN8", "target": "species_10053120" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083455", "target": "A0A3Q1LPN8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056293", "target": "reaction_10056297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050064", "target": "species_10056293" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050064", "target": "O62830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62830", "target": "species_10056295" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056276", "target": "reaction_10056289" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056315", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056315", "target": "species_10056276" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056315", "target": "species_10053116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056315", "target": "species_76577" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056315", "target": "species_10056313" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056311", "target": "reaction_10056315" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM71", "target": "species_10056311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM71", "target": "species_10056313" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010366", "target": "F1MM71" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056313", "target": "reaction_10060694" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056283", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056283", "target": "species_10056276" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056283", "target": "species_10053116" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056283", "target": "species_10056280" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056283", "target": "species_76577" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039246", "target": "reaction_10056283" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031869", "target": "species_10039246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031869", "target": "Q4JF28" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031869", "target": "species_10039546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10056280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10039552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10039558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10040195" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10053091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10053093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10056080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10056086" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10039556" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10056078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10040189" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10056076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10065395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4JF28", "target": "species_10065400" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060730", "target": "species_10060724" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060730", "target": "species_10060728" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060726", "target": "reaction_10060730" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFK0", "target": "species_10060726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFK0", "target": "species_10060724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075646", "target": "A0A3Q1MFK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8U3", "target": "species_10060726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8U3", "target": "species_10060724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086252", "target": "A0A3Q1M8U3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL22", "target": "species_10060726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL22", "target": "species_10060724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL22", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL22", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021327", "target": "Q2NL22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ54", "target": "species_10060726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ54", "target": "species_10060724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000144", "target": "Q3SZ54" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060706", "target": "reaction_10060730" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSC2", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSC2", "target": "species_10060728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSC2", "target": "species_10060704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086202", "target": "A0A3Q1LSC2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086202", "target": "A0A3Q1MRS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS1", "target": "species_10060706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS1", "target": "species_10060728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS1", "target": "species_10060704" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060732", "target": "species_10060706" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060704", "target": "reaction_10060732" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056287", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056287", "target": "species_10056276" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056287", "target": "species_10053116" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056287", "target": "species_10056285" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056287", "target": "species_76577" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055358", "target": "reaction_10056287" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056289", "target": "species_10056278" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056270", "target": "reaction_10056289" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060694", "target": "species_10056311" }, { "type": "product", "sub_type": "", "source": "reaction_10060694", "target": "species_141681" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060689", "target": "reaction_10060694" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086230", "target": "species_10060689" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089341", "target": "species_10089339" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053104", "target": "reaction_10089341" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053104", "target": "reaction_10053122" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089337", "target": "reaction_10089341" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004270", "target": "species_10089337" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004270", "target": "F1MXX7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXX7", "target": "species_10089339" }, { "type": "product", "sub_type": "", "source": "reaction_10089696", "target": "species_9009945" }, { "type": "reactant", "sub_type": "", "source": "species_170292", "target": "reaction_10089696" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089693", "target": "reaction_10089696" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089349", "target": "species_10089347" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089345", "target": "reaction_10089349" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089343", "target": "reaction_10089349" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089703", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089703", "target": "species_113592" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089703", "target": "species_76577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8983696", "target": "reaction_10089703" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089700", "target": "reaction_10089703" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020675", "target": "species_10089700" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057588", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057585", "target": "reaction_10057588" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ50", "target": "species_10057585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074252", "target": "A0A3Q1LQ50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGH7", "target": "species_10057585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011399", "target": "E1BGH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLI5", "target": "species_10057585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025779", "target": "F1MLI5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091423", "target": "species_10091421" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9647661", "target": "reaction_10091423" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037243", "target": "reaction_10091423" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037243", "target": "reaction_10091415" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037243", "target": "reaction_10091425" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037243", "target": "reaction_10092356" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10037243" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "A0A3Q1MD51" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10091431" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10092343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10092345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10091407" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10091433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087110", "target": "species_10091437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10091421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10081899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10081901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10091413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10037245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MD51", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8954419", "target": "species_10091421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8954419", "target": "species_10037245" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8954419", "target": "species_10037251" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8954419", "target": "reaction_10092356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8954419", "target": "reaction_10092358" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8954419", "target": "reaction_10088649" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092350", "target": "species_10092343" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092350", "target": "species_10092345" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091431", "target": "reaction_10092350" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091431", "target": "reaction_10092341" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091431", "target": "reaction_10091439" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10092347", "target": "reaction_10092350" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091409", "target": "species_10081901" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081899", "target": "reaction_10091409" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10081899" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10081901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10081903" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_5620974" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10091413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10091427" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806180", "target": "reaction_10060614" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806180", "target": "species_10072328" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081901", "target": "reaction_10081905" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10091407", "target": "reaction_10091409" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10091407", "target": "reaction_10091425" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081905", "target": "species_10081502" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044670", "target": "reaction_10081905" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024094", "target": "species_10044670" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024094", "target": "species_10081502" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024094", "target": "P10103" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081502", "target": "reaction_10081506" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081502", "target": "reaction_10081510" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081903", "target": "reaction_10081905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFC3", "target": "species_10081903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFC3", "target": "species_10091427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFC3", "target": "species_10037251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080428", "target": "E1BFC3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080428", "target": "species_10037249" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080428", "target": "species_10091417" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080428", "target": "species_10091419" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092341", "target": "species_10037243" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092341", "target": "species_10091433" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092338", "target": "reaction_10092341" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O75601", "target": "species_10092338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027820", "target": "O75601" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091415", "target": "species_10091413" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5620974", "target": "reaction_10091415" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5620974", "target": "reaction_10091429" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5620974", "target": "reaction_10072346" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091413", "target": "reaction_10091425" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091439", "target": "species_10037243" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091439", "target": "species_10091433" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10091437", "target": "reaction_10091439" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091425", "target": "species_10081899" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092352", "target": "species_10081903" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091427", "target": "reaction_10092352" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037249", "target": "reaction_10092352" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037249", "target": "reaction_10091429" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037249", "target": "reaction_10092358" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092354", "target": "species_10037249" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092354", "target": "species_10091419" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091417", "target": "reaction_10092354" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091429", "target": "species_10091427" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037253", "target": "species_10037211" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037239", "target": "reaction_10037253" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037235", "target": "reaction_10037253" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037235", "target": "reaction_10037264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KI7", "target": "species_10037235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KI7", "target": "species_10037620" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000549", "target": "Q05KI7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000549", "target": "species_10037233" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037245", "target": "reaction_10037253" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037251", "target": "reaction_10037253" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092356", "target": "species_10037245" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092358", "target": "species_10037251" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091817", "target": "species_10091815" }, { "type": "reactant", "sub_type": "other", "source": "species_9678991", "target": "reaction_10091817" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056239", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056239", "target": "species_10039728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056236", "target": "reaction_10056239" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044568", "target": "species_10044555" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044568", "target": "species_10044553" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044551", "target": "reaction_10044568" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023373", "target": "species_10044551" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023373", "target": "species_10044555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023373", "target": "species_10044553" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044565", "target": "reaction_10044568" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044565", "target": "reaction_10044578" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044565", "target": "reaction_10044995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X702", "target": "species_10044565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X702", "target": "species_10044753" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016642", "target": "G3X702" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090575", "target": "species_10044565" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044753", "target": "reaction_10090575" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044753", "target": "reaction_10044756" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044578", "target": "species_10044576" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044578", "target": "species_10044574" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044572", "target": "reaction_10044578" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036080", "target": "species_10036078" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036080", "target": "species_10036072" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036074", "target": "reaction_10036080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM18", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086549", "target": "A0A3Q1MM18" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LW50", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076380", "target": "A0A3Q1LW50" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076380", "target": "E1BHK8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076380", "target": "F1N150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK8", "target": "species_10041037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N150", "target": "species_10041037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Z8", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021643", "target": "Q3T0Z8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFN1", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFN1", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFN1", "target": "species_10036911" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033237", "target": "A4IFN1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBL0", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007241", "target": "Q3ZBL0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKH0", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKH0", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKH0", "target": "species_10036911" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013683", "target": "F1MKH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10036911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M973", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001380", "target": "A0A3Q1M973" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N038", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N038", "target": "species_10036072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N038", "target": "species_10036911" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016000", "target": "F1N038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Z1", "target": "species_10036074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Z1", "target": "species_10036078" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0Z1", "target": "species_10036050" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074628", "target": "A0A3Q1N0Z1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074628", "target": "species_10036048" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036072", "target": "reaction_10036076" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036072", "target": "reaction_10036917" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036915", "target": "species_10036913" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036915", "target": "species_10036072" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036911", "target": "reaction_10036915" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083967", "target": "species_10083965" }, { "type": "reactant", "sub_type": "", "source": "species_8851965", "target": "reaction_10083967" }, { "type": "reactant", "sub_type": "", "source": "species_8851965", "target": "reaction_10083959" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083963", "target": "reaction_10083967" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049415", "target": "species_10083963" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049415", "target": "A6QNP4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNP4", "target": "species_10083965" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083959", "target": "species_10083957" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083955", "target": "reaction_10083959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045031", "target": "species_10083955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045031", "target": "F1MZI6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZI6", "target": "species_10083957" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046811", "target": "species_10046809" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046779", "target": "reaction_10046811" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046779", "target": "reaction_10046787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046779" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046820" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ND77", "target": "species_10046949" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079588", "target": "A0A3Q1ND77" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046793", "target": "reaction_10046811" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046820" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP81", "target": "species_10046901" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079899", "target": "A0A3S5ZP81" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046907", "target": "species_10046818" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046907", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037459", "target": "reaction_10046907" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037459", "target": "reaction_10046943" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037459", "target": "reaction_10049300" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046905", "target": "reaction_10046907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046818" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046936" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046940" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046820" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLL9", "target": "species_10046901" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081673", "target": "A0A3Q1MLL9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081673", "target": "species_10046783" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046818", "target": "reaction_10046822" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046818", "target": "reaction_10046951" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043788", "target": "reaction_10046907" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043788", "target": "reaction_10046909" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043788", "target": "reaction_10044039" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10047530", "target": "species_10047527" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047530", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047008", "target": "reaction_10047530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080762", "target": "species_10047008" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046932", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046932", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046929", "target": "reaction_10046932" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046787", "target": "species_10046785" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046783", "target": "reaction_10046787" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046943", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046943", "target": "species_10046940" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046936", "target": "reaction_10046943" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046822", "target": "species_10046820" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046951", "target": "species_10046949" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046834", "target": "species_10046832" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046830", "target": "reaction_10046834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019810", "target": "species_10046830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019810", "target": "E1BCU8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046826", "target": "reaction_10046834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028775", "target": "species_10046826" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028775", "target": "Q58DF9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DF9", "target": "species_10046832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU8", "target": "species_10046832" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046909", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046909", "target": "species_10046899" }, { "type": "product", "sub_type": "", "source": "reaction_10046909", "target": "species_10041566" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046805", "target": "reaction_10046909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28090", "target": "species_10046805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28090", "target": "species_10046899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28090", "target": "species_10046801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28090", "target": "species_10046803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28090", "target": "species_10046901" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017527", "target": "Q28090" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046899", "target": "reaction_10046903" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046959", "target": "species_10046803" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046801", "target": "reaction_10046959" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046803", "target": "reaction_10046807" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046807", "target": "species_10046805" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046795", "target": "reaction_10046807" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046903", "target": "species_10046901" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075923", "target": "species_10075921" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075919", "target": "reaction_10075923" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081458", "target": "species_10075919" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081458", "target": "A0A3Q1NI55" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NI55", "target": "species_10075921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065019", "target": "species_10065017" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065015", "target": "reaction_10065019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEG8", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074178", "target": "A0A3Q1MEG8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074178", "target": "species_10065053" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q30309", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014072", "target": "Q30309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y1", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019939", "target": "A6H6Y1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQE7", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003342", "target": "A6QQE7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLZ1", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034283", "target": "E1BLZ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0X9", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019800", "target": "F1N0X9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N610", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026100", "target": "F1N610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJU5", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018484", "target": "F1MJU5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI49", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085256", "target": "A0A3Q1MI49" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085256", "target": "F1ML60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUX0", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078884", "target": "A0A3Q1MUX0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML60", "target": "species_10064212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M088", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075226", "target": "A0A3Q1M088" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWT2", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064718", "target": "G3MWT2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10065015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10065017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10063931" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10063937" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10065049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10063941" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10065007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10063925" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10084399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064223" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q70IB5", "target": "species_10064212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063954", "target": "Q70IB5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064164", "target": "reaction_10065019" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064219", "target": "species_10063937" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063931", "target": "reaction_10064219" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063937", "target": "reaction_10063972" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064216", "target": "reaction_10064219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10064216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10063969" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25326", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022774", "target": "P25326" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065051", "target": "species_10065045" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065051", "target": "species_10065049" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065047", "target": "reaction_10065051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT7", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT7", "target": "species_10065045" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008504", "target": "F1MHT7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KTP6", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KTP6", "target": "species_10065045" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065976", "target": "Q5KTP6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLV2", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLV2", "target": "species_10065045" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020881", "target": "F1MLV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW7", "target": "species_10065047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DW7", "target": "species_10065045" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016520", "target": "Q58DW7" }, { "type": "reactant", "sub_type": "", "source": "species_2213226", "target": "reaction_10065051" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065045", "target": "reaction_10065055" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065021", "target": "species_10064116" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065021", "target": "species_10064225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064275", "target": "reaction_10065021" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064116", "target": "reaction_10064118" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064225", "target": "reaction_10064277" }, { "type": "product", "sub_type": "", "source": "reaction_10064221", "target": "species_2213226" }, { "type": "reactant", "sub_type": "", "source": "species_2213225", "target": "reaction_10064221" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063969", "target": "reaction_10064221" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063969", "target": "reaction_10063972" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCU3", "target": "species_10063969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014587", "target": "Q0VCU3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065055", "target": "species_10065047" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065055", "target": "species_10065053" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063941", "target": "reaction_10065055" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065009", "target": "species_10063925" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065007", "target": "reaction_10065009" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084401", "target": "species_10084399" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064210", "target": "reaction_10084401" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084397", "target": "reaction_10084401" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077596", "target": "species_10084397" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077596", "target": "A0A3Q1LYZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYZ8", "target": "species_10084399" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065011", "target": "species_10064164" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064162", "target": "reaction_10065011" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064138", "target": "reaction_10065011" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064277", "target": "species_10064275" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064223", "target": "reaction_10064277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064118", "target": "species_10064020" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064020", "target": "reaction_10064068" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064214", "target": "species_10064212" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064066", "target": "reaction_10064214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064068", "target": "species_10064066" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063972", "target": "species_10063941" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042635", "target": "species_10042633" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042631", "target": "reaction_10042635" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027169", "target": "species_10042631" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027169", "target": "Q3ZC60" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042627", "target": "reaction_10042635" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001635", "target": "species_10042627" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001635", "target": "A5D7V5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7V5", "target": "species_10042633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC60", "target": "species_10042633" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042253", "target": "species_10042251" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042245", "target": "reaction_10042253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEF6", "target": "species_10042245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEF6", "target": "species_10042251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012194", "target": "F1MEF6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RKH9", "target": "species_10042245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RKH9", "target": "species_10042251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025279", "target": "F6RKH9" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042249", "target": "reaction_10042253" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068738", "target": "species_10042249" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068738", "target": "A0A3Q1MBF2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBF2", "target": "species_10042251" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042623", "target": "species_10042621" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042615", "target": "reaction_10042623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076490", "target": "species_10042615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076490", "target": "A7YWT5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042619", "target": "reaction_10042623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083396", "target": "species_10042619" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083396", "target": "A0A3Q1M4X8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10042621" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048338" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4X8", "target": "species_10048340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWT5", "target": "species_10042621" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042129", "target": "species_10042127" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042125", "target": "reaction_10042129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC47", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC47", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046313", "target": "F1MC47" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D2", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3D2", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000064618", "target": "A0A3Q1M3D2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP3", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP3", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050022", "target": "F1MBP3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT21", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT21", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067721", "target": "A0A3Q1MT21" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJB8", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJB8", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054092", "target": "F1MJB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLJ5", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLJ5", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055909", "target": "E1BLJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYX4", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYX4", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085379", "target": "A0A3Q1MYX4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCU4", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCU4", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016878", "target": "Q0VCU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28072", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28072", "target": "species_10042127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28072", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28072", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008462", "target": "Q28072" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MAZ7", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MAZ7", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028175", "target": "A7MAZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YW30", "target": "species_10042125" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YW30", "target": "species_10042127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033046", "target": "A7YW30" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074993", "target": "species_10074991" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1006168", "target": "reaction_10074993" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1006168", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1006168", "target": "species_1006146" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1006168", "target": "species_10055969" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074989", "target": "reaction_10074993" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10074989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHX4", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081728", "target": "A0A3Q1MHX4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10074989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR7", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064604", "target": "G3MZR7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10074989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8E5", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052760", "target": "E1B8E5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10074989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ8", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011656", "target": "E1BKZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10074989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10074991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MST2", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031802", "target": "F1MST2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075009", "target": "species_10075007" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074999", "target": "reaction_10075009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJG8", "target": "species_10074999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJG8", "target": "species_10075007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042955", "target": "A5PJG8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075005", "target": "reaction_10075009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBN7", "target": "species_10075005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBN7", "target": "species_10075007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082969", "target": "A0A3Q1NBN7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084672", "target": "species_10084670" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084640", "target": "reaction_10084672" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001412", "target": "species_10084640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001412", "target": "F1MJX3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084668", "target": "reaction_10084672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7F4", "target": "species_10084668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7F4", "target": "species_10084670" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017867", "target": "E1B7F4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y6", "target": "species_10084668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H6Y6", "target": "species_10084670" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065575", "target": "A6H6Y6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJX3", "target": "species_10084670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJX3", "target": "species_10084650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJX3", "target": "species_10084656" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074899", "target": "species_10074897" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074895", "target": "reaction_10074899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLN1", "target": "species_10074895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLN1", "target": "species_10074897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034482", "target": "F1MLN1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034482", "target": "species_10074893" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074889", "target": "reaction_10074899" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBB1", "target": "species_10074889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBB1", "target": "species_10074897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036966", "target": "Q3ZBB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F1", "target": "species_10074889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F1", "target": "species_10074897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085516", "target": "A0A3Q1M4F1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076963", "target": "species_10076961" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5696348", "target": "reaction_10076963" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1500646", "target": "species_5696348" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1500646", "target": "species_10076961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500646", "target": "reaction_10058943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500646", "target": "reaction_10085310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500646", "target": "reaction_10058945" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500646", "target": "reaction_10059014" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1500646", "target": "species_947594" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1500646", "target": "species_947588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076959", "target": "reaction_10076963" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNL2", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNL2", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020853", "target": "F1MNL2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI56", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI56", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008500", "target": "E1BI56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGI2", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGI2", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010642", "target": "F1MGI2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10076961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFU3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040027", "target": "E1BFU3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10076961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML46", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071567", "target": "A0A3Q1ML46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX01", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX01", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070885", "target": "A0A3Q1LX01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG16", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG16", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003593", "target": "F1MG16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT87", "target": "species_10076959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT87", "target": "species_10076961" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077738", "target": "A0A3Q1MT87" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10042786", "target": "species_10042784" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042782", "target": "reaction_10042786" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042780", "target": "reaction_10042786" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W5", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5W5", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011326", "target": "G5E5W5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011326", "target": "G5E5B4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPQ5", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPQ5", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080712", "target": "Q8SPQ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME80", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME80", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077038", "target": "A0A3Q1ME80" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ30", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ30", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081128", "target": "A0A3Q1MQ30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQD8", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQD8", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053352", "target": "F1MQD8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X797", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X797", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022538", "target": "G3X797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5B4", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5B4", "target": "species_10042784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5G6", "target": "species_10042780" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5G6", "target": "species_10042784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018094", "target": "G5E5G6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084658", "target": "species_10084656" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084654", "target": "reaction_10084658" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087222", "target": "species_10084654" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087222", "target": "A0A3Q1NN33" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084650", "target": "reaction_10084658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN37", "target": "species_10084650" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN37", "target": "species_10084656" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072757", "target": "A0A3Q1MN37" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NN33", "target": "species_10084656" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074901", "target": "species_10074895" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074893", "target": "reaction_10074901" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043241", "target": "species_10043239" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043234", "target": "reaction_10043241" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043262", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043262", "target": "species_112275" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043259", "target": "reaction_10043262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10043259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10066099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10072362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10072385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMD9", "target": "species_10061110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074574", "target": "A0A3Q1MMD9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074574", "target": "species_10072008" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074574", "target": "species_10072059" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074574", "target": "species_10049069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074574", "target": "species_10037554" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043193", "target": "species_10043191" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043189", "target": "reaction_10043193" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074583", "target": "species_10043189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074583", "target": "A0A3Q1MCW9" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043191", "target": "reaction_10043244" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCW9", "target": "species_10043191" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043225", "target": "species_10043223" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043006", "target": "reaction_10043225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043223", "target": "reaction_10066147" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043219", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043219", "target": "species_202247" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_202247", "target": "reaction_10060429" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_202247", "target": "reaction_10060590" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043216", "target": "reaction_10043219" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043216", "target": "reaction_10044034" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043252", "target": "species_10043250" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043248", "target": "reaction_10043252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081933", "target": "species_10043248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081933", "target": "A0A3S5ZPB2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081933", "target": "species_10043265" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081933", "target": "species_10066109" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081933", "target": "species_10066122" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043180", "target": "reaction_10043252" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043180", "target": "reaction_10043212" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043180" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043295" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043281" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043267" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043272" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_202277" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043293" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043287" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_10043289" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806238", "target": "species_8849959" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806238", "target": "reaction_10060588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043250", "target": "reaction_10043270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10043289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066170" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB2", "target": "species_10066178" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043304", "target": "species_10043281" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043279", "target": "reaction_10043304" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043295", "target": "reaction_10043304" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043274", "target": "species_10043272" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043267", "target": "reaction_10043274" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043265", "target": "reaction_10043274" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043272", "target": "reaction_10043300" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043244", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043244", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043212", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043212", "target": "species_10043209" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043202", "target": "reaction_10043212" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043202", "target": "reaction_10066059" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043209", "target": "reaction_10043270" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043182", "target": "species_10043180" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_202277", "target": "reaction_10043182" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043298", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043298", "target": "species_10043295" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043293", "target": "reaction_10043298" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041331", "target": "reaction_10043298" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020312", "target": "species_10041331" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043300", "target": "species_10043293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043270", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043270", "target": "species_10043267" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043302", "target": "species_10043289" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043287", "target": "reaction_10043302" }, { "type": "product", "sub_type": "", "source": "reaction_10055448", "target": "species_983123" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055448", "target": "species_10055330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055446", "target": "reaction_10055448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK96", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK96", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK96", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK96", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068172", "target": "A0A3Q1LK96" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M231", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M231", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M231", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M231", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070128", "target": "A0A3Q1M231" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV49", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV49", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV49", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV49", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082004", "target": "A0A3Q1LV49" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMK0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMK0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMK0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMK0", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010691", "target": "Q1RMK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7A0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7A0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7A0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7A0", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015476", "target": "F1N7A0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FKI3", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FKI3", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FKI3", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M5FKI3", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070499", "target": "M5FKI3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4U5R4", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4U5R4", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4U5R4", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4U5R4", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039156", "target": "Q4U5R4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRV4", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRV4", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRV4", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRV4", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRV4", "target": "species_10066548" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018459", "target": "Q7YRV4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018459", "target": "species_10054900" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEX6", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEX6", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEX6", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEX6", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010969", "target": "F1MEX6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBI7", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBI7", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBI7", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBI7", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081934", "target": "E1BBI7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUP8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079583", "target": "A0A3Q1MUP8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S2", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S2", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S2", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S2", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000291", "target": "F1N0S2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7V0", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7V0", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7V0", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7V0", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009741", "target": "G3X7V0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C1", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C1", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C1", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7C1", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027362", "target": "F1N7C1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5X8", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5X8", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5X8", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5X8", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048180", "target": "F1N5X8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B964", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B964", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B964", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B964", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012816", "target": "E1B964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD1", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD1", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD1", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD1", "target": "species_10055424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD1", "target": "species_10084297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005377", "target": "A6QQD1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ2", "target": "species_10055446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ2", "target": "species_10055330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ2", "target": "species_10055428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCZ2", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012423", "target": "E1BCZ2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055330", "target": "reaction_10055453" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10055330", "target": "reaction_10055431" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055451", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055451", "target": "species_10055446" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055451", "target": "species_10055420" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055451", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10055428", "target": "reaction_10055451" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055422", "target": "reaction_10055451" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055422", "target": "reaction_10055453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1X1", "target": "species_10055422" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1X1", "target": "species_10055420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1X1", "target": "species_10055424" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076465", "target": "A0A3Q1N1X1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055453", "target": "species_10055424" }, { "type": "reactant", "sub_type": "", "source": "species_983035", "target": "reaction_10055453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055424", "target": "reaction_10055431" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055491", "target": "species_983032" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055491", "target": "species_8942986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_983036", "target": "reaction_10055491" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10055488", "target": "reaction_10055491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP91", "target": "species_10055488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015199", "target": "E1BP91" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL29", "target": "species_10055488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028490", "target": "E1BL29" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055431", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055431", "target": "species_10055428" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055431", "target": "species_10055420" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055431", "target": "species_76577" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061657", "target": "species_10061655" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061653", "target": "reaction_10061657" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058452" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058454" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q50JB9", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072863", "target": "Q50JB9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W5I5", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069740", "target": "Q5W5I5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02775", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009756", "target": "O02775" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P25068", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "P25068" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "F1MGE0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "G3MWU3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "G3MXI5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "A0A3Q1ME63" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "A0A452DIQ0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074783", "target": "E1BHH4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46165", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018930", "target": "P46165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28880", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050266", "target": "Q28880" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGE0", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWU3", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWY5", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064773", "target": "G3MWY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXI5", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0J5", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086067", "target": "A0A3Q1M0J5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME63", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIQ0", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10061653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10061655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHH4", "target": "species_10058386" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045084", "target": "reaction_10061657" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058456", "target": "species_10058454" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058452", "target": "reaction_10058456" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1462049", "target": "reaction_10058456" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10058454" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_8931784" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10082010" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10083098" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10082002" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10081941" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10081391" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10087599" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10081395" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1462049", "target": "species_10084704" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058492", "target": "species_10058490" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058488", "target": "reaction_10058492" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWB5", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWB5", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWB5", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWB5", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWB5", "target": "species_10058386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078433", "target": "A0A3Q1LWB5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078433", "target": "A0A3Q1M5C9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078433", "target": "A0A3Q1MT20" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5C9", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5C9", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5C9", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5C9", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5C9", "target": "species_10058386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT20", "target": "species_10058488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT20", "target": "species_10058490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT20", "target": "species_10058484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT20", "target": "species_10058328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT20", "target": "species_10058386" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058486", "target": "species_10058452" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058484", "target": "reaction_10058486" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063801", "target": "species_2090070" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063801", "target": "species_1678617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090055", "target": "reaction_10063801" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060675", "target": "reaction_10063801" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060675", "target": "reaction_10060678" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060675", "target": "reaction_10060827" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075910", "target": "species_10060675" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063803", "target": "species_1678743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063803", "target": "species_2065212" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090053", "target": "reaction_10063803" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2065212", "target": "reaction_10060741" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060682", "target": "reaction_10063803" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060682", "target": "reaction_10060685" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071251", "target": "species_10060682" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060634", "target": "species_2090069" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060634", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090040", "target": "reaction_10060634" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10060634" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10063805" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10043917" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10044540" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10044835" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10044837" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10083496" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10038316" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76183", "target": "reaction_10039918" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090069", "target": "reaction_10060685" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060631", "target": "reaction_10060634" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060631", "target": "reaction_10063805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIE9", "target": "species_10060631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIE9", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIE9", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIE9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIE9", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079230", "target": "A0A3Q1MIE9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060685", "target": "species_2090080" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060685", "target": "species_1678743" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090080", "target": "reaction_10060625" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063805", "target": "species_2090053" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063805", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090045", "target": "reaction_10063805" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060671", "target": "species_2090023" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060671", "target": "species_10060664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060650", "target": "reaction_10060671" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060650", "target": "reaction_10063022" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060668", "target": "reaction_10060671" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085333", "target": "species_10060668" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063022", "target": "species_10060394" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060625", "target": "species_2090055" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060625", "target": "species_1606845" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060622", "target": "reaction_10060625" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060622", "target": "reaction_10060825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2D5", "target": "species_10060622" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014683", "target": "F1N2D5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060741", "target": "species_1678868" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060741", "target": "species_2090075" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060738", "target": "reaction_10060741" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060738", "target": "reaction_10064595" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060738", "target": "reaction_10064597" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY8", "target": "species_10060738" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY8", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY8", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY8", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY8", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000941", "target": "A3KMY8" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_427963", "target": "reaction_10060741" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_427963", "target": "species_428027" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_427963", "target": "species_427997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060678", "target": "species_2090072" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060678", "target": "species_1678617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2090033", "target": "reaction_10060678" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072894", "target": "species_5653871" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072894", "target": "species_205687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072891", "target": "reaction_10072894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYQ2", "target": "species_10072891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066421", "target": "A0A3Q1LYQ2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066421", "target": "species_10072896" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072898", "target": "species_10072891" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072896", "target": "reaction_10072898" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054442", "target": "reaction_10072898" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_5653875", "target": "reaction_10072898" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_29372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_29578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_29360" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_29800" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033611", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29578", "target": "reaction_10033611" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29578", "target": "reaction_10033620" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29578", "target": "reaction_10034071" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29578", "target": "reaction_10034041" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29578", "target": "reaction_10034043" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29800", "target": "reaction_10033611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29800", "target": "reaction_10088737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29800", "target": "reaction_10078710" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033608", "target": "reaction_10033611" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10096", "target": "species_10033608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037753", "target": "P10096" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJE5", "target": "species_10033608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021166", "target": "Q2KJE5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080765", "target": "species_29512" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080765", "target": "species_31633" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080762", "target": "reaction_10080765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIC9", "target": "species_10080762" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000357", "target": "A0A452DIC9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033629", "target": "species_30014" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033629", "target": "species_29370" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_30014", "target": "reaction_10034157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30014", "target": "reaction_10034071" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30014", "target": "reaction_10033638" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_30014", "target": "reaction_10036928" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033626", "target": "reaction_10033629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4J1", "target": "species_10033626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4J1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4J1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4J1", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4J1", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056305", "target": "A1A4J1" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_30533", "target": "reaction_10033629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30533", "target": "reaction_10072557" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_76190", "target": "reaction_10033629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034157", "target": "species_113592" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034157", "target": "species_29398" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034154", "target": "reaction_10034157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPG7", "target": "species_10034154" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086042", "target": "Q1JPG7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D984", "target": "species_10034154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D984", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D984", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D984", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D984", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047412", "target": "A5D984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034140", "target": "species_29728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034140", "target": "species_30485" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29728", "target": "reaction_10034140" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29728", "target": "reaction_10054620" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_30485", "target": "reaction_10034140" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034049", "target": "reaction_10034140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ62", "target": "species_10034049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ62", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ62", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ62", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ62", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032937", "target": "Q3SZ62" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076815", "target": "species_30537" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076815", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70113", "target": "reaction_10076815" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70113", "target": "reaction_10072825" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_189227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_189254" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_429078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_429148" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_189075" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_70113", "target": "species_189071" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_70113", "target": "reaction_10044634" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30537", "target": "reaction_10088737" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30537", "target": "reaction_10041885" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30537", "target": "reaction_10067240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30537", "target": "reaction_10033592" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_30537", "target": "reaction_10067644" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076812", "target": "reaction_10076815" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE47", "target": "species_10076812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002065", "target": "A2VE47" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088737", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088737", "target": "species_8955759" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088737", "target": "species_29728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033547", "target": "reaction_10088737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKH8", "target": "species_10033547" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKH8", "target": "species_10033549" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001019", "target": "A5PKH8" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033620", "target": "species_75970" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033620", "target": "species_29578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_75970", "target": "reaction_10033620" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_75970", "target": "reaction_10034071" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_75970", "target": "reaction_10035812" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033617", "target": "reaction_10033620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIX3", "target": "species_10033617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026358", "target": "A0A452DIX3" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034071", "target": "species_30014" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034071", "target": "species_29578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034071", "target": "species_75970" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034066", "target": "reaction_10034071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10034066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB0", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017416", "target": "A0A3S5ZPB0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078710", "target": "species_6798337" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10078707", "target": "reaction_10078710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX69", "target": "species_10078707" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070308", "target": "F1MX69" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10045050", "target": "species_29372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10045050", "target": "species_113544" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045050", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045050", "target": "species_198498" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_198498", "target": "reaction_10045050" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_198498", "target": "reaction_10045692" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_198498", "target": "reaction_10041878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_198498", "target": "reaction_10060218" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045047", "target": "reaction_10045050" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045047", "target": "reaction_10060218" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000538", "target": "species_10045047" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033757", "target": "species_113587" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033757", "target": "species_113552" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033757", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033757", "target": "species_113553" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041885", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041885", "target": "species_113782" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113551", "target": "reaction_10041885" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113551", "target": "reaction_10067240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113782", "target": "reaction_10034238" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113782", "target": "reaction_10067254" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113782", "target": "reaction_10067247" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041882", "target": "reaction_10041885" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077820", "target": "species_10041882" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045692", "target": "species_29406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045692", "target": "species_113544" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041875", "target": "reaction_10045692" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041875", "target": "reaction_10041878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22292", "target": "species_10041875" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079666", "target": "P22292" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034238", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034238", "target": "species_113780" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034235", "target": "reaction_10034238" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013436", "target": "species_10034235" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045043", "target": "species_372364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045043", "target": "species_113525" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045043", "target": "species_29376" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113573", "target": "reaction_10045043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113573", "target": "reaction_10077864" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113573", "target": "reaction_10056002" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045040", "target": "reaction_10045043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015834", "target": "species_10045040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10041878", "target": "species_29406" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10041878", "target": "species_113544" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041878", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041878", "target": "species_198498" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033718", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033718", "target": "species_76213" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76213", "target": "reaction_10033716" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033713", "target": "reaction_10033718" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033713", "target": "reaction_10033716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33097", "target": "species_10033713" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015873", "target": "P33097" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067254", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067254", "target": "species_113780" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067251", "target": "reaction_10067254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005552", "target": "species_10067251" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067240", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067240", "target": "species_113782" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067237", "target": "reaction_10067240" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069229", "target": "species_10067237" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067247", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067247", "target": "species_113780" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067244", "target": "reaction_10067247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021621", "target": "species_10067244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045029", "target": "species_29448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045029", "target": "species_113552" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045026", "target": "reaction_10045029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9V5", "target": "species_10045026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083179", "target": "A0A3Q1M9V5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHX4", "target": "species_10045026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073854", "target": "A0A3Q1LHX4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033638", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033638", "target": "species_29512" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033635", "target": "reaction_10033638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZB7", "target": "species_10033635" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012835", "target": "Q3SZB7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033561", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033561", "target": "species_31221" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29532", "target": "reaction_10033561" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_29532", "target": "reaction_10043971" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29532", "target": "species_429078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29532", "target": "species_429148" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29532", "target": "reaction_10043910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033558", "target": "reaction_10033561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II75", "target": "species_10033558" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015052", "target": "Q0II75" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083115", "target": "species_6799497" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083115", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083115", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30393", "target": "reaction_10083115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30393", "target": "reaction_10033570" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034172", "target": "reaction_10083115" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034172", "target": "reaction_10034175" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033570", "target": "species_29578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033570", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033567", "target": "reaction_10033570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGZ4", "target": "species_10033567" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085239", "target": "A0A3Q1MGZ4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072825", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072825", "target": "species_5652213" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063530", "target": "species_10063493" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063530", "target": "species_727810" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063528", "target": "reaction_10063530" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063493", "target": "reaction_10063508" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063485", "target": "species_10063483" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063470", "target": "reaction_10063485" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063532", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063532", "target": "species_10063528" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063518", "target": "reaction_10063532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063249", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063249", "target": "species_10063240" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063230", "target": "reaction_10063249" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063240", "target": "reaction_10063520" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063246", "target": "reaction_10063249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA01", "target": "species_10063246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030023", "target": "Q5EA01" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063232", "target": "species_10063230" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063232", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063222", "target": "reaction_10063232" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063520", "target": "species_10063518" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063520", "target": "species_205687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063477", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063477", "target": "species_10063470" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063464", "target": "reaction_10063477" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10063474", "target": "reaction_10063477" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004844", "target": "species_10063474" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063508", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063508", "target": "species_10063464" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063505", "target": "reaction_10063508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMN6", "target": "species_10063505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015389", "target": "E1BMN6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK55", "target": "species_10063505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056191", "target": "E1BK55" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060825", "target": "species_2065269" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060825", "target": "species_1606845" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2065213", "target": "reaction_10060825" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2065269", "target": "reaction_10091289" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2065269", "target": "reaction_10063807" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091289", "target": "species_1605658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091289", "target": "species_2105025" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2105025", "target": "reaction_10060827" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060827", "target": "species_2104993" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060827", "target": "species_1678617" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060842", "target": "species_2065212" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2065257", "target": "reaction_10060842" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63512", "target": "species_2065257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63512", "target": "species_2065251" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63513", "target": "species_2065257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63513", "target": "species_2065251" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63515", "target": "species_2065257" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2065239", "target": "species_2065257" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060839", "target": "reaction_10060842" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060839", "target": "reaction_10064355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSK8", "target": "species_10060839" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000611", "target": "F1MSK8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060829", "target": "species_2065239" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060829", "target": "species_1606845" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2065251", "target": "reaction_10060829" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060028", "target": "reaction_10060829" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060028", "target": "reaction_10060031" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062655", "target": "species_10062627" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062655", "target": "species_10062653" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062551", "target": "reaction_10062655" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10063012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10062667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21809", "target": "species_10065689" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047242", "target": "P21809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047242", "target": "species_10062553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10063012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY84", "target": "species_10062667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016206", "target": "F1MY84" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10063012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCM1", "target": "species_10062667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002979", "target": "Q0VCM1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10063012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10062667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21793", "target": "species_10065298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061629" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061557" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10063012" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061200" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10061327" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062699" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2Y8", "target": "species_10062667" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002312", "target": "F1N2Y8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062589", "target": "reaction_10062655" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060031", "target": "species_1606845" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060031", "target": "species_2065213" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2065231", "target": "reaction_10060031" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063807", "target": "species_1605658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063807", "target": "species_2105025" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061642", "target": "species_10061574" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061642", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061629", "target": "reaction_10061642" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061574", "target": "reaction_10061612" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061574", "target": "reaction_10062463" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061639", "target": "reaction_10061642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM8", "target": "species_10061639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMM8", "target": "species_10061648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027366", "target": "E1BMM8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N783", "target": "species_10061639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N783", "target": "species_10061648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019521", "target": "F1N783" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061612", "target": "species_10061591" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061612", "target": "species_742343" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061609", "target": "reaction_10061612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N663", "target": "species_10061609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014069", "target": "F1N663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M362", "target": "species_10061609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073469", "target": "A0A3Q1M362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ9", "target": "species_10061609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011567", "target": "A6QLZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTD8", "target": "species_10061609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068924", "target": "A0A3Q1MTD8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10062463", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062463", "target": "species_10062450" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062460", "target": "reaction_10062463" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6P1", "target": "species_10062460" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010069", "target": "G3X6P1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPN4", "target": "species_10062460" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074793", "target": "E1BPN4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061651", "target": "species_10061629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061651", "target": "species_205687" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1889970", "target": "reaction_10061651" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1889970", "target": "reaction_10061350" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1889970", "target": "reaction_10091286" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061557", "target": "reaction_10061651" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061648", "target": "reaction_10061651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9D0", "target": "species_10061648" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019108", "target": "E1B9D0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063014", "target": "species_10062589" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063012", "target": "reaction_10063014" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061402", "target": "species_10061388" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061402", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061238", "target": "reaction_10061402" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061388", "target": "reaction_10061395" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061399", "target": "reaction_10061402" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035663", "target": "species_10061399" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061251", "target": "species_10061238" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061251", "target": "species_205687" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061200", "target": "reaction_10061251" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_742361", "target": "reaction_10061251" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061248", "target": "reaction_10061251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N211", "target": "species_10061248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007264", "target": "F1N211" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSF3", "target": "species_10061248" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070229", "target": "A0A3Q1LSF3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061395", "target": "species_205687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061395", "target": "species_10061289" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061289", "target": "reaction_10061350" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10061289", "target": "reaction_10091286" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061392", "target": "reaction_10061395" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057493", "target": "species_10061392" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061350", "target": "species_10061327" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061350", "target": "species_205687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061347", "target": "reaction_10061350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0B6", "target": "species_10061347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083529", "target": "A0A3Q1M0B6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LG25", "target": "species_10061347" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LG25", "target": "species_10061345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080834", "target": "A0A3Q1LG25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ60", "target": "species_10061347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070592", "target": "F1MQ60" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091286", "target": "species_10061327" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091286", "target": "species_205687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061345", "target": "reaction_10091286" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10062697", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062697", "target": "species_10062690" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062676", "target": "reaction_10062697" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10062694", "target": "reaction_10062697" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005795", "target": "species_10062694" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062701", "target": "species_10062551" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062699", "target": "reaction_10062701" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062508", "target": "species_10062501" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062465", "target": "reaction_10062508" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10062505", "target": "reaction_10062508" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056960", "target": "species_10062505" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10062674", "target": "species_742343" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062674", "target": "species_10062667" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062482", "target": "reaction_10062674" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10062671", "target": "reaction_10062674" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068674", "target": "species_10062671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039887", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039887", "target": "species_158471" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174370", "target": "reaction_10039887" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10051570" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040152" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040120" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040122" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040157" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10038320" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040112" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040147" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040117" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10038231" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040136" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040107" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10038318" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040131" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10040098" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158471", "target": "reaction_10038340" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039884", "target": "reaction_10039887" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039884", "target": "reaction_10039890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC88", "target": "species_10039884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070040", "target": "Q0VC88" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R031", "target": "species_10039884" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017229", "target": "F6R031" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039890", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039890", "target": "species_174370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174375", "target": "reaction_10039890" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051570", "target": "species_741440" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051567", "target": "reaction_10051570" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010620", "target": "species_10051567" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048727", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048727", "target": "species_174375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427648", "target": "reaction_10048727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427648", "target": "reaction_10049333" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048724", "target": "reaction_10048727" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019462", "target": "species_10048724" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064353", "target": "species_2142896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2142867", "target": "reaction_10064353" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_2142896" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_2160848" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_10064375" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_2160864" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_2160866" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2162224", "target": "reaction_10064595" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_10064388" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2162224", "target": "species_2160894" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064350", "target": "reaction_10064353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071722", "target": "species_10064350" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064393", "target": "species_10064375" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10064359", "target": "reaction_10064393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070191", "target": "species_10064359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070191", "target": "Q8SQG8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064373", "target": "reaction_10064393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE8", "target": "species_10064373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE8", "target": "species_10064375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE8", "target": "species_10064388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080269", "target": "A0A3Q1MJE8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6UC88", "target": "species_10064373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6UC88", "target": "species_10064375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6UC88", "target": "species_10064388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001061", "target": "Q6UC88" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYW1", "target": "species_10064373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYW1", "target": "species_10064375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYW1", "target": "species_10064388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007896", "target": "F1MYW1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2160848", "target": "reaction_10064393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQG8", "target": "species_10064375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SQG8", "target": "species_10064388" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091291", "target": "species_1678743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091291", "target": "species_2162224" }, { "type": "reactant", "sub_type": "", "source": "species_2162223", "target": "reaction_10091291" }, { "type": "reactant", "sub_type": "", "source": "species_2162223", "target": "reaction_10064593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064593", "target": "species_1678743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064593", "target": "species_2162224" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064355", "target": "species_2160866" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2160864", "target": "reaction_10064355" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2160866", "target": "reaction_10064597" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064595", "target": "species_1678743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064595", "target": "species_1678868" }, { "type": "product", "sub_type": "", "source": "reaction_10064597", "target": "species_2162223" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064597", "target": "species_1678868" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064391", "target": "species_2160894" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064391", "target": "species_10064388" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064388", "target": "reaction_10064391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS44", "target": "species_10064388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071051", "target": "A0A3Q1LS44" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033579", "target": "species_29410" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29452", "target": "reaction_10033579" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033576", "target": "reaction_10033579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP2", "target": "species_10033576" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006586", "target": "A0A452DIP2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033594", "target": "species_30537" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033549", "target": "reaction_10033594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10033549" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10033541" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QEU6", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007589", "target": "F6QEU6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090620", "target": "species_205687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090620", "target": "species_9033802" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9033793", "target": "reaction_10090620" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9033793", "target": "reaction_10090631" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090617", "target": "reaction_10090620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8N6", "target": "species_10090617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8N6", "target": "species_10090635" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8N6", "target": "species_10090642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8N6", "target": "species_10090628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081124", "target": "A0A3Q1M8N6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090703", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090703", "target": "species_9037036" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9036984", "target": "reaction_10090703" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9036984", "target": "reaction_10090799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9036984", "target": "reaction_10090802" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090700", "target": "reaction_10090703" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090700", "target": "reaction_10090772" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090700", "target": "reaction_10090774" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028720", "target": "species_10090700" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090638", "target": "species_417888" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090638", "target": "species_9037066" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9034101", "target": "reaction_10090638" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9034101", "target": "reaction_10090645" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9034046", "target": "reaction_10090638" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090635", "target": "reaction_10090638" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090611", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090611", "target": "species_9033793" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9033790", "target": "reaction_10090611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9033790", "target": "reaction_10090797" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9033790", "target": "reaction_10090851" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090608", "target": "reaction_10090611" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023560", "target": "species_10090608" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090645", "target": "species_417888" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090645", "target": "species_9037067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9034065", "target": "reaction_10090645" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090642", "target": "reaction_10090645" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090631", "target": "species_9033798" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090631", "target": "species_205687" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090628", "target": "reaction_10090631" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090856", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090856", "target": "species_9605651" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605649", "target": "reaction_10090856" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090797", "target": "species_9605593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090797", "target": "species_205689" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605593", "target": "reaction_10090774" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090794", "target": "reaction_10090797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDG4", "target": "species_10090794" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056091", "target": "F1MDG4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBS8", "target": "species_10090794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBS8", "target": "species_10090864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N751", "target": "species_10090794" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010501", "target": "F1N751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090799", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090799", "target": "species_9605607" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605607", "target": "reaction_10090772" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090819", "target": "species_205687" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090819", "target": "species_9036984" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9604808", "target": "reaction_10090819" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090816", "target": "reaction_10090819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJA3", "target": "species_10090816" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036248", "target": "Q2HJA3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSJ4", "target": "species_10090816" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031889", "target": "F1MSJ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0R9", "target": "species_10090816" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022206", "target": "Q3T0R9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090851", "target": "species_727810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090851", "target": "species_9605685" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605685", "target": "reaction_10090867" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090848", "target": "reaction_10090851" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090867", "target": "species_9605661" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090867", "target": "species_205689" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090864", "target": "reaction_10090867" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZR2", "target": "species_10090864" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066072", "target": "G3MZR2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090802", "target": "species_727810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090802", "target": "species_9605595" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605595", "target": "reaction_10090854" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9605595", "target": "reaction_10090822" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054713", "target": "reaction_10090802" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090772", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090772", "target": "species_9605394" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090774", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090774", "target": "species_9605586" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090854", "target": "species_9605615" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090854", "target": "species_205689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090822", "target": "species_727810" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090822", "target": "species_9605649" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10069341", "target": "reaction_10090822" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034041", "target": "species_29790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034041", "target": "species_73578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034041", "target": "species_29882" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034041", "target": "species_29578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29790", "target": "reaction_10034041" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29790", "target": "reaction_10034043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29790", "target": "reaction_10042801" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29882", "target": "reaction_10034041" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034038", "target": "reaction_10034041" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034038", "target": "reaction_10034043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z014", "target": "species_10034038" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004892", "target": "A7Z014" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033592", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033592", "target": "species_31467" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033592", "target": "species_29364" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033589", "target": "reaction_10033592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM55", "target": "species_10033589" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067626", "target": "A0A3Q1MM55" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034043", "target": "species_29790" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10034043", "target": "species_29878" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034043", "target": "species_29578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034043", "target": "species_29512" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29878", "target": "reaction_10034043" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034013", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034013", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034013", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034013", "target": "species_29732" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29996", "target": "reaction_10034013" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29732", "target": "reaction_10042801" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29732", "target": "reaction_10034032" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034010", "target": "reaction_10034013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPM3", "target": "species_10034010" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017988", "target": "A0A3S5ZPM3" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10042801", "target": "species_29790" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042801", "target": "species_29732" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034029", "target": "reaction_10042801" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034029", "target": "reaction_10034032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7P1", "target": "species_10034029" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082970", "target": "A5D7P1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034032", "target": "species_29790" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088744", "target": "species_73578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088744", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8955853", "target": "reaction_10088744" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088741", "target": "reaction_10088744" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044396", "target": "species_10088741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089230", "target": "species_6787328" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6787326", "target": "reaction_10089230" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033541", "target": "reaction_10089230" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033541", "target": "reaction_10077793" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077793", "target": "species_73578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_112016", "target": "reaction_10077793" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_112016", "target": "species_500244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088898", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088898", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088898", "target": "species_29882" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8959707", "target": "reaction_10088898" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088895", "target": "reaction_10088898" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001095", "target": "species_10088895" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073438", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073438", "target": "species_5661268" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5661264", "target": "reaction_10073438" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10073435", "target": "reaction_10073438" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10073435", "target": "reaction_10076133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000630", "target": "species_10073435" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073431", "target": "species_5660033" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073431", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5660036", "target": "reaction_10073431" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073428", "target": "reaction_10073431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJR3", "target": "species_10073428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085766", "target": "A5PJR3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085766", "target": "Q1JP75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JP75", "target": "species_10073428" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080747", "target": "species_429579" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080747", "target": "species_6799543" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6799540", "target": "reaction_10080747" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080744", "target": "reaction_10080747" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWT0", "target": "species_10080744" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009690", "target": "F1MWT0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084129", "target": "species_6799577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084129", "target": "species_6799594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8853396", "target": "reaction_10084129" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6799577", "target": "reaction_10080756" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084126", "target": "reaction_10084129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29451", "target": "species_10084126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29451", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29451", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070599", "target": "Q29451" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080756", "target": "species_6799594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080756", "target": "species_8853719" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080753", "target": "reaction_10080756" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEZ5", "target": "species_10080753" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081381", "target": "A0A3Q1MEZ5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067610", "target": "species_10067607" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067610", "target": "species_110096" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067605", "target": "reaction_10067610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10068745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10068740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10068750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10068734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB78", "target": "species_10067617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007423", "target": "A7MB78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10068745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10068740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067627" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10068750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10068734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10067617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10090685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10090689" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10034111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10034135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10034099" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLJ5", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077965", "target": "A0A3Q1NLJ5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067607", "target": "reaction_10067634" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067644", "target": "species_110096" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067644", "target": "species_10067641" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067619", "target": "reaction_10067644" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067641", "target": "reaction_10067648" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068748", "target": "species_10068740" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068748", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068745", "target": "reaction_10068748" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR4", "target": "species_10068745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR4", "target": "species_10068740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR4", "target": "species_10068750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCR4", "target": "species_10068734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019753", "target": "Q0VCR4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019753", "target": "species_10068729" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067648", "target": "species_10067646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067631", "target": "reaction_10067648" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067631", "target": "reaction_10067634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083071", "target": "species_10067631" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068752", "target": "species_10068750" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067627", "target": "reaction_10068752" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068729", "target": "reaction_10068752" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068750", "target": "reaction_10068755" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068755", "target": "species_109402" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068755", "target": "species_10068734" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067634", "target": "species_10067627" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067639", "target": "species_10067605" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067639", "target": "species_110096" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067636", "target": "reaction_10067639" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067622", "target": "species_10067619" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067622", "target": "species_110096" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067617", "target": "reaction_10067622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090696", "target": "species_1605745" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090696", "target": "species_10090689" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090685", "target": "reaction_10090696" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090691", "target": "reaction_10090696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021325", "target": "species_10090691" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021325", "target": "Q9MYM4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034138", "target": "species_10034135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034138", "target": "species_70113" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034111", "target": "reaction_10034138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZJ1", "target": "species_10034111" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZJ1", "target": "species_10034135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZJ1", "target": "species_10034099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085404", "target": "A0A3Q1LZJ1" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034115", "target": "reaction_10034138" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034115", "target": "reaction_10034118" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008518", "target": "species_10034115" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008518", "target": "F1MHT1" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10050637", "target": "species_10050635" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050637", "target": "species_10034078" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050637", "target": "species_76577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050635", "target": "reaction_10050637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ28", "target": "species_10050635" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ28", "target": "species_10034078" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001373", "target": "F1MJ28" }, { "type": "product", "sub_type": "complex_component", "source": "species_10034078", "target": "reaction_10050637" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034118", "target": "species_10034111" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10034099", "target": "reaction_10034118" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_29356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_113592" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_29448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_29472" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_29642" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033737", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033734", "target": "reaction_10033737" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZA3", "target": "species_10033734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079655", "target": "Q1LZA3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078529", "target": "species_29448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078529", "target": "species_29382" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078526", "target": "reaction_10078529" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066927", "target": "species_10078526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033728", "target": "species_113587" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033728", "target": "species_113552" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076130", "target": "species_29416" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076130", "target": "species_29448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5691492", "target": "reaction_10076130" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5691492", "target": "reaction_10087455" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076127", "target": "reaction_10076130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUZ8", "target": "species_10076127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069554", "target": "F1MUZ8" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033716", "target": "species_29404" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033716", "target": "species_76213" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033716", "target": "species_29406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033716", "target": "species_29448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076406", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076406", "target": "species_5693772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693762", "target": "reaction_10076406" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076403", "target": "reaction_10076406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUP1", "target": "species_10076403" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009723", "target": "F1MUP1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGS8", "target": "species_10076403" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000354", "target": "F1MGS8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043917", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043917", "target": "species_209793" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043914", "target": "reaction_10043917" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019543", "target": "species_10043914" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043948", "target": "species_71112" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043948", "target": "species_209911" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29500", "target": "reaction_10043948" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29500", "target": "reaction_10052027" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29500", "target": "reaction_10041894" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10043945", "target": "reaction_10043948" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5Q8", "target": "species_10043945" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007030", "target": "F1N5Q8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGX6", "target": "species_10043945" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027708", "target": "E1BGX6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033681", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033681", "target": "species_29398" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033678", "target": "reaction_10033681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIW8", "target": "species_10033678" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010309", "target": "A0A452DIW8" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091773", "target": "species_10091771" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091773", "target": "species_10091769" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070522", "target": "reaction_10091773" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070522", "target": "reaction_10091793" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070522", "target": "reaction_10091810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068030", "target": "species_10068028" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035394", "target": "reaction_10068030" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10035394", "target": "reaction_10037985" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10035394", "target": "reaction_10035396" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10035394", "target": "reaction_10037991" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068026", "target": "reaction_10068030" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068026", "target": "reaction_10074240" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074240", "target": "species_10068032" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068034", "target": "reaction_10074240" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068032", "target": "reaction_10068042" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074254", "target": "species_10074251" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091806", "target": "species_10091803" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091797", "target": "reaction_10091806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G3", "target": "species_10091797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G3", "target": "species_10091803" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G3", "target": "species_10091795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7G3", "target": "species_10089672" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025473", "target": "E1B7G3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025473", "target": "species_10055082" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091793", "target": "species_10091786" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091793", "target": "species_110096" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091790", "target": "reaction_10091793" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045447", "target": "species_10091790" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091808", "target": "species_10072344" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072342", "target": "reaction_10091808" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023165", "target": "species_10072342" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023165", "target": "E1BKM4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045220", "target": "reaction_10091808" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045220", "target": "reaction_10045224" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045220", "target": "reaction_10069418" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026526", "target": "species_10045220" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026526", "target": "F6QH17" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10072344", "target": "reaction_10072346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH17", "target": "species_10072344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH17", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH17", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH17", "target": "species_10045222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QH17", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKM4", "target": "species_10072344" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091779", "target": "species_10091777" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070680", "target": "reaction_10091779" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070680", "target": "reaction_10070689" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091810", "target": "species_10091797" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091795", "target": "reaction_10091810" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091783", "target": "species_10091781" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994146", "target": "reaction_10091783" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_994146", "target": "species_10091781" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070686", "target": "reaction_10091783" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629770", "target": "reaction_10091783" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1629770", "target": "species_10091781" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629770", "target": "reaction_10061079" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629770", "target": "reaction_10061125" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994141", "target": "reaction_10091783" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_994141", "target": "species_10091781" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994141", "target": "reaction_10061116" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994141", "target": "reaction_10061011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081481", "target": "species_6803745" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081481", "target": "species_6803778" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6803725", "target": "reaction_10081481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:85299", "target": "species_6803725" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:85263", "target": "species_6803725" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:71464", "target": "species_6803725" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:85262", "target": "species_6803725" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081478", "target": "reaction_10081481" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN16", "target": "species_10081478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025945", "target": "F1MN16" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044540", "target": "species_264643" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044540", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_264618", "target": "reaction_10044540" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_264618", "target": "reaction_10059063" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044537", "target": "reaction_10044540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022369", "target": "species_10044537" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049090", "target": "species_264618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049090", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049090", "target": "species_352022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_264638", "target": "reaction_10049090" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_264638", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_264638", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_264638", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_264638", "target": "species_549250" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049087", "target": "reaction_10049090" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005693", "target": "species_10049087" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071437", "target": "species_10071435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071423", "target": "reaction_10071437" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071423", "target": "reaction_10078488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071329", "target": "species_10071423" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071329", "target": "A0A3Q1LPV4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071419", "target": "reaction_10071437" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079326", "target": "species_10071419" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079326", "target": "A0A3Q1MLH9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071433", "target": "reaction_10071437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LM6", "target": "species_10071433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LM6", "target": "species_10071435" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070192", "target": "Q32LM6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHU4", "target": "species_10071433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHU4", "target": "species_10071435" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001914", "target": "A0A452DHU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLH9", "target": "species_10071435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPV4", "target": "species_10071435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPV4", "target": "species_10078486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPV4", "target": "species_10078520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049583", "target": "species_352011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049583", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049583", "target": "species_352022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352003", "target": "reaction_10049583" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352011", "target": "reaction_10052018" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049580", "target": "reaction_10049583" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJX7", "target": "species_10049580" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019308", "target": "A5PJX7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPI1", "target": "species_10049580" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038826", "target": "E1BPI1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052018", "target": "species_428571" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10052015", "target": "reaction_10052018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063578", "target": "species_10052015" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063578", "target": "species_10048962" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052013", "target": "species_352011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052013", "target": "species_113528" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052010", "target": "reaction_10052013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCA1", "target": "species_10052010" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCA1", "target": "species_10051996" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009547", "target": "Q0VCA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6X2", "target": "species_10052010" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010598", "target": "F1N6X2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051999", "target": "species_352011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051999", "target": "species_113528" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051996", "target": "reaction_10051999" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051989", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051989", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051989", "target": "species_113536" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_880046", "target": "reaction_10051989" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051986", "target": "reaction_10051989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDP3", "target": "species_10051986" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029203", "target": "E1BDP3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033755", "target": "species_113561" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033755", "target": "species_113552" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113522", "target": "reaction_10033755" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033752", "target": "reaction_10033755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ6", "target": "species_10033752" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012233", "target": "E1BHZ6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044461", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044461", "target": "species_29472" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_212615", "target": "reaction_10044461" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044076", "target": "species_74126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044076", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044076", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044076", "target": "species_83910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044069", "target": "reaction_10044076" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044069", "target": "reaction_10048804" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJN4", "target": "species_10044069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025456", "target": "F1MJN4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H774", "target": "species_10044069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017953", "target": "A6H774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46411", "target": "species_10044069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024287", "target": "P46411" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT8", "target": "species_10044069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016615", "target": "F1MUT8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR13", "target": "species_10044069" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069455", "target": "A0A3Q1MR13" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10044074", "target": "reaction_10044076" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028661", "target": "species_10044074" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033746", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033746", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033746", "target": "species_29472" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033743", "target": "reaction_10033746" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P15103", "target": "species_10033743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074216", "target": "P15103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044086", "target": "species_29404" }, { "type": "catalyst", "sub_type": "", "source": "species_10044083", "target": "reaction_10044086" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054361", "target": "species_352022" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054358", "target": "reaction_10054361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA32", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068615", "target": "A0A3Q1MA32" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHX4", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015688", "target": "F1MHX4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E50", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080524", "target": "Q08E50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE96", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017637", "target": "E1BE96" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08219", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009483", "target": "P08219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08220", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023711", "target": "P08220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJH4", "target": "species_10054358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060999", "target": "E1BJH4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054372", "target": "species_352022" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054369", "target": "reaction_10054372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B988", "target": "species_10054369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001857", "target": "E1B988" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051085", "target": "species_10051083" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050486", "target": "reaction_10051085" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091067", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091067", "target": "species_10091064" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091060", "target": "reaction_10091067" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091075", "target": "species_10091073" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091071", "target": "reaction_10091075" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010230", "target": "species_10091071" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010230", "target": "F6RXS3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RXS3", "target": "species_10091073" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090547", "target": "species_10090545" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090537", "target": "reaction_10090547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054318", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054318", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054318", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054315", "target": "reaction_10054318" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1Q1", "target": "species_10054315" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062928", "target": "G3N1Q1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y2", "target": "species_10054315" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y2", "target": "species_10091518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4Y2", "target": "species_10091523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014292", "target": "F1N4Y2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAL4", "target": "species_10054315" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056946", "target": "E1BAL4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5G0", "target": "species_10054315" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055354", "target": "F1N5G0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5J6", "target": "species_10054315" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022113", "target": "G5E5J6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091521", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091521", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091521", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091518", "target": "reaction_10091521" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091525", "target": "species_10091518" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091523", "target": "reaction_10091525" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051521", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051518", "target": "reaction_10051521" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDD1", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDD1", "target": "species_10051516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039651", "target": "F1MDD1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF30", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF30", "target": "species_10051516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF30", "target": "species_10051495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MF30", "target": "species_10051493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039752", "target": "F1MF30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK0", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK0", "target": "species_10051516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK0", "target": "species_10051495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHK0", "target": "species_10051493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022855", "target": "E1BHK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ06", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ06", "target": "species_10051516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ06", "target": "species_10051495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ06", "target": "species_10051493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018679", "target": "F1MQ06" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJN8", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJN8", "target": "species_10051516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJN8", "target": "species_10051495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJN8", "target": "species_10051493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075573", "target": "A0A3Q1MJN8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPI7", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPI7", "target": "species_10051516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020942", "target": "A6QPI7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPU7", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8SPU7", "target": "species_10051516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018151", "target": "Q8SPU7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4T3", "target": "species_10051518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4T3", "target": "species_10051516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4T3", "target": "species_10051495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4T3", "target": "species_10051493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002910", "target": "F1N4T3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051523", "target": "species_10051518" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051516", "target": "reaction_10051523" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051498", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051495", "target": "reaction_10051498" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051525", "target": "species_10051495" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051493", "target": "reaction_10051525" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065894", "target": "species_10065892" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065890", "target": "reaction_10065894" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070781", "target": "species_10065890" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070781", "target": "A0A3Q1M4J2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J2", "target": "species_10065892" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039217", "target": "species_10039215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_166005", "target": "reaction_10039217" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166005", "target": "species_10039215" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_166005", "target": "reaction_10081510" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166005", "target": "species_10081508" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166005", "target": "species_6803074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166005", "target": "species_10081430" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_166005", "target": "reaction_10081397" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_166005", "target": "species_10082975" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039213", "target": "reaction_10039217" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039213", "target": "reaction_10085369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062921", "target": "species_10039213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062921", "target": "G3N2G9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2G9", "target": "species_10039215" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2G9", "target": "species_10085367" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039560", "target": "species_10039558" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039552", "target": "reaction_10039560" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039552", "target": "reaction_10056090" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039558", "target": "reaction_10040197" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040197", "target": "species_10040195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085369", "target": "species_10085367" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2186967", "target": "reaction_10085369" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2186967", "target": "species_10085367" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081506", "target": "species_10081504" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_181015", "target": "reaction_10081506" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_181015", "target": "species_10081504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10081504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10081508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10044676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10103", "target": "species_10044678" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081510", "target": "species_10081508" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060783", "target": "species_10060769" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060783", "target": "species_10060751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060783", "target": "species_211606" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10060783", "target": "species_10060763" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060771", "target": "reaction_10060783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIF7", "target": "species_10060771" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074388", "target": "A0A3Q1MIF7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074388", "target": "species_10060763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10060771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10060751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10060757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10060781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10091735" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MK24", "target": "species_10091737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079344", "target": "A0A3Q1MK24" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079344", "target": "species_10060749" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060769", "target": "reaction_10060773" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060751", "target": "reaction_10060759" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060763", "target": "reaction_10060773" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060785", "target": "species_10060781" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060757", "target": "reaction_10060785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBH4", "target": "species_10060757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBH4", "target": "species_10060781" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001581", "target": "E1BBH4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001581", "target": "species_10060755" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060773", "target": "species_10060771" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060749", "target": "reaction_10060773" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060759", "target": "species_10060757" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060755", "target": "reaction_10060759" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091739", "target": "species_10091737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091735", "target": "reaction_10091739" }, { "type": "reactant", "sub_type": "other", "source": "species_9678628", "target": "reaction_10091739" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066168", "target": "species_10066165" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066168", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066165", "target": "reaction_10066168" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066059", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066059", "target": "species_10066057" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066057", "target": "reaction_10066127" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066141", "target": "species_10066139" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066131", "target": "reaction_10066141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066139", "target": "reaction_10066180" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066172", "target": "species_10066170" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066124", "target": "reaction_10066172" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066109", "target": "reaction_10066172" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066127", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066127", "target": "species_10066124" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066122", "target": "reaction_10066127" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066147", "target": "species_10043202" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066147", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065638", "target": "reaction_10066147" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065638", "target": "reaction_10065642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N342", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N342", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N342", "target": "species_10065640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065204", "target": "G3N342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNU1", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNU1", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNU1", "target": "species_10065640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026773", "target": "E1BNU1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10065638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10066049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10065640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072370" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10072372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BDR7", "target": "species_10050628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034054", "target": "Q9BDR7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066180", "target": "species_10066178" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066120", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066120", "target": "species_10065617" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066117", "target": "reaction_10066120" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066065", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066065", "target": "species_10066063" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066061", "target": "reaction_10066065" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066082", "target": "species_10065486" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065484", "target": "reaction_10066082" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066151", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066151", "target": "species_10065484" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066149", "target": "reaction_10066151" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066049", "target": "reaction_10066151" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066049", "target": "reaction_10066052" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066080", "target": "species_10066078" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066076", "target": "reaction_10066080" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066078", "target": "reaction_10066144" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066144", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066144", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065642", "target": "species_10065640" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066094", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066094", "target": "species_112275" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066091", "target": "reaction_10066094" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSH3", "target": "species_10066091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSH3", "target": "species_10066042" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSH3", "target": "species_10066047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSH3", "target": "species_10066099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046704", "target": "F1MSH3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066052", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066052", "target": "species_10066047" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066042", "target": "reaction_10066052" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066047", "target": "reaction_10066102" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066102", "target": "species_10066099" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066102", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081085", "target": "species_10081083" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081071", "target": "reaction_10081085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05204", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05204", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05204", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05204", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045121", "target": "Q05204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10047270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4J0", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072837", "target": "A0A3Q1M4J0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10047270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NMT9", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070673", "target": "A0A3Q1NMT9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10047270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG6", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012873", "target": "F1MRG6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10047270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ44", "target": "species_10047290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045380", "target": "F1MZ44" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCF4", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012484", "target": "E1BCF4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS24", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS24", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS24", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS24", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS24", "target": "species_10056528" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075240", "target": "A0A3Q1MS24" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10037716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P61285", "target": "species_10037718" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081563", "target": "P61285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWC4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWC4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWC4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWC4", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012676", "target": "A7YWC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S2", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S2", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S2", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3S2", "target": "species_10040626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064122", "target": "G3N3S2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ0", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ0", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ0", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043753", "target": "A6QLZ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCZ8", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCZ8", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCZ8", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCZ8", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067584", "target": "A0A3Q1MCZ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZT3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069265", "target": "A0A3Q1LZT3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPJ1", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPJ1", "target": "species_10081083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017459", "target": "A0A3S5ZPJ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIW8", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIW8", "target": "species_10081083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018382", "target": "F1MIW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ5", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005511", "target": "E1BGJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNM6", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081334", "target": "A0A3Q1NNM6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E574", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "G5E574" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "G5E671" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1NNG7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "E1BFM6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "E1BNM1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1M953" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1MX09" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1N1V7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1NNA9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1LN32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1LWA7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084846", "target": "A0A3Q1M411" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E671", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNG7", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFM6", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNM1", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXU0", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084657", "target": "G3MXU0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M953", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MX09", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1V7", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNA9", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN32", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA7", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J2", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074686", "target": "A0A3Q1M1J2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M411", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9MYM4", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWC4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWC4", "target": "species_10081083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077476", "target": "A0A3Q1LWC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD53", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD53", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD53", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD53", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035679", "target": "E1BD53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KII9", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019566", "target": "Q2KII9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023242", "target": "F1N0T3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PZJ9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PZJ9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PZJ9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PZJ9", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PZJ9", "target": "species_10043345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084844", "target": "F6PZJ9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084844", "target": "species_10043343" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDP5", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDP5", "target": "species_10081083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004547", "target": "A2VDP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10089021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL2", "target": "species_10089026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N4", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5N4", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026431", "target": "G5E5N4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL92", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL92", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL92", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL92", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066802", "target": "A0A3Q1LL92" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVA6", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVA6", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVA6", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVA6", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066593", "target": "A0A3Q1LVA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z4", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z4", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z4", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z4", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026429", "target": "E1B6Z4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHT5", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020277", "target": "E1BHT5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJK0", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJK0", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJK0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJK0", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001458", "target": "A5PJK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5S0", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028846", "target": "G5E5S0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMS1", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000367", "target": "Q1RMS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHU6", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHU6", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHU6", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHU6", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020198", "target": "F1MHU6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMZ3", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMZ3", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMZ3", "target": "species_10045222" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069125", "target": "A0A3Q1LMZ3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069125", "target": "species_10045216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JN39", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008616", "target": "A0JN39" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B876", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B876", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B876", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B876", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047448", "target": "E1B876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072378" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3LUH2", "target": "species_10072385" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032346", "target": "Q3LUH2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBC9", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073497", "target": "A0A3Q1NBC9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073497", "target": "A0A452DJ67" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ67", "target": "species_10091362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDF5", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDF5", "target": "species_10081083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049662", "target": "E1BDF5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10081071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10081083" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10072370" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4H1", "target": "species_10072372" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055016", "target": "F1N4H1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10079949", "target": "species_10079947" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10079839", "target": "reaction_10079949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10076309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10075286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10076345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10075288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10075292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10076283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA7", "target": "species_10076314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013758", "target": "A7MBA7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10076309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10075286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10076345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10075288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10075292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10076283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMD5", "target": "species_10076314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008020", "target": "F1MMD5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA23", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA23", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA23", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA23", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA23", "target": "species_10035998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021018", "target": "E1BA23" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ57", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ57", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ57", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ57", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021704", "target": "Q2HJ57" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI43", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI43", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI43", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI43", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008107", "target": "A0A452DI43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRP0", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRP0", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRP0", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRP0", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000876", "target": "F1MRP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E987", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E987", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E987", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E987", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027507", "target": "Q5E987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68401", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68401", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68401", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68401", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007398", "target": "P68401" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCI9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018917", "target": "Q3ZCI9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79105", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79105", "target": "species_10079947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063314", "target": "P79105" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFC3", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFC3", "target": "species_10079947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069599", "target": "A0A3Q1MFC3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKG9", "target": "species_10079947" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078914", "target": "A5PKG9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078914", "target": "species_10049287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5I2E5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5I2E5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5I2E5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5I2E5", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084171", "target": "Q5I2E5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QP9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QP9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QP9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QP9", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWU9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWU9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWU9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWU9", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057500", "target": "F1MWU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ46", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ46", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ46", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ46", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028608", "target": "Q2KJ46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10067741" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMV5", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084460", "target": "A0A3Q1LMV5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT1", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHT1", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F9", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F9", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9F9", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065774", "target": "Q5E9F9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10035314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SWY3", "target": "species_10035317" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025179", "target": "Q3SWY3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ25", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ25", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ25", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJ25", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003145", "target": "Q2KJ25" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJA8", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJA8", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJA8", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJA8", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJA8", "target": "species_10035450" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016346", "target": "A0A452DJA8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX83", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX83", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX83", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX83", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001309", "target": "A0A3Q1LX83" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001309", "target": "Q3T0Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Y5", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWE0", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWE0", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWE0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWE0", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028983", "target": "F1MWE0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGS0", "target": "species_10035004" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074118", "target": "A0A3Q1MGS0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T831", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000683", "target": "A0A140T831" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62935", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62935", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62935", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P62935", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015924", "target": "P62935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIT4", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023325", "target": "A0A452DIT4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023325", "target": "species_10043423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10040669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DK5", "target": "species_10040686" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000315", "target": "Q58DK5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68103", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68103", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68103", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68103", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1A3", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1A3", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1A3", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1A3", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073135", "target": "A0A3Q1N1A3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073135", "target": "A0A3Q1N4Z1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073135", "target": "A0A3Q1NLY8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4Z1", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4Z1", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4Z1", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4Z1", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY8", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY8", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY8", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY8", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIE3", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIE3", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIE3", "target": "species_10035432" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000841", "target": "A0A452DIE3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPS7", "target": "species_10079839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPS7", "target": "species_10079947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPS7", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPS7", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084564", "target": "A0A3Q1LPS7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080063", "target": "species_10080061" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080039", "target": "reaction_10080063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA9", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRA9", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080425", "target": "A0A3Q1LRA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33046", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33046", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33046", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33046", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P33046", "target": "species_10056537" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044788", "target": "P33046" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044788", "target": "species_10056535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044788", "target": "species_10081382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPI3", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPI3", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPI3", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPI3", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026661", "target": "E1BPI3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCL0", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCL0", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCL0", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCL0", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076131", "target": "Q3ZCL0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB5", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB5", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB5", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2LGB5", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010835", "target": "Q2LGB5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLB1", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLB1", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016464", "target": "A6QLB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2J3", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079464", "target": "A0A3Q1M2J3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Y2", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Y2", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Y2", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8Y2", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000001395", "target": "E1B8Y2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC41", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC41", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC41", "target": "species_10090589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC41", "target": "species_10090591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMV5", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003618", "target": "F6RMV5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z6", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z6", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z6", "target": "species_10070902" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6Z6", "target": "species_10070904" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018806", "target": "E1B6Z6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVJ8", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVJ8", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVJ8", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVJ8", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030920", "target": "F1MVJ8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD23", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD23", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD23", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD23", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045994", "target": "F1MD23" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46675", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46675", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46675", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46675", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039536", "target": "O46675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10056414" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10082963" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P24627", "target": "species_10082965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001704", "target": "P24627" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001704", "target": "species_10056412" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWG4", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009917", "target": "A7YWG4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80189", "target": "species_10084681" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038266", "target": "P80189" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038266", "target": "species_10079373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW13", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW13", "target": "species_10080061" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009806", "target": "F1MW13" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHQ1", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHQ1", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHQ1", "target": "species_10076853" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007133", "target": "Q3MHQ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF76", "target": "species_10080039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF76", "target": "species_10080061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF76", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IF76", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074688", "target": "A4IF76" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080719", "target": "species_10080717" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080687", "target": "reaction_10080719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29455", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29455", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29455", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29455", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070817", "target": "Q29455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T5", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T5", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021761", "target": "F1N3T5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021761", "target": "species_10051896" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAL1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAL1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAL1", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAL1", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070277", "target": "A0A3Q1MAL1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP64", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP64", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP64", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP64", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068539", "target": "A0A3Q1MP64" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0A2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0A2", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074088", "target": "A0A3Q1M0A2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNV7", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083870", "target": "A0A3Q1LNV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H797", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H797", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026715", "target": "A6H797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFT3", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFT3", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFT3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFT3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084806", "target": "A0A3Q1MFT3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFU2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFU2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFU2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFU2", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083623", "target": "A4IFU2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0X5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0X5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0X5", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0X5", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068372", "target": "A0A3Q1N0X5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFE2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFE2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFE2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFE2", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020345", "target": "E1BFE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1F5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1F5", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021843", "target": "F1N1F5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DM3", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DM3", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DM3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DM3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008479", "target": "Q58DM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNL9", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNL9", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNL9", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNL9", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027255", "target": "E1BNL9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6K1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6K1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI97", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI97", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI97", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI97", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020710", "target": "Q2KI97" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4C7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4C7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E4P3", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052503", "target": "A8E4P3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10077901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF89", "target": "species_10065881" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076616", "target": "A0A3Q1NF89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTY9", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTY9", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047056", "target": "F1MTY9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047056", "target": "species_10040633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN89", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN89", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008168", "target": "F1MN89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N680", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N680", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N680", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N680", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026019", "target": "F1N680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZS9", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZS9", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZS9", "target": "species_10035783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035230", "target": "F1MZS9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10085749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10085751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ27", "target": "species_10043353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069303", "target": "A0A3Q1MQ27" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069303", "target": "species_10043351" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMX5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMX5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMX5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMX5", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069044", "target": "F1MMX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2M7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2M7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2M7", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2M7", "target": "species_10079651" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2M7", "target": "species_10065988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073921", "target": "A0A3Q1M2M7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PA1", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PA1", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PA1", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PA1", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002967", "target": "Q32PA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R7", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026770", "target": "F1N3R7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFF5", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFF5", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFF5", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFF5", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026308", "target": "A4IFF5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPK7", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075634", "target": "A0A3Q1LPK7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075634", "target": "A0A3Q1MSR2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSR2", "target": "species_10091362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M288", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M288", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M288", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M288", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085751", "target": "A0A3Q1M288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QRN7", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6QRN7", "target": "species_10080717" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005137", "target": "Q6QRN7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPW8", "target": "species_10080687" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPW8", "target": "species_10080717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPW8", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPW8", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075991", "target": "A0A3Q1LPW8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10079391", "target": "species_10079389" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10079319", "target": "reaction_10079391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W1C4", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W1C4", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W1C4", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5W1C4", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080090", "target": "Q5W1C4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNC0", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNC0", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNC0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNC0", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MNC0", "target": "species_10059178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034356", "target": "A0A3Q1MNC0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034356", "target": "A0A3Q1NGZ9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034356", "target": "F1MUL1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGZ9", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGZ9", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGZ9", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGZ9", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NGZ9", "target": "species_10059178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUL1", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUL1", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUL1", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUL1", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUL1", "target": "species_10059178" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHK8", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHK8", "target": "species_10079389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034879", "target": "Q3MHK8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBE7", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBE7", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBE7", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBE7", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032525", "target": "Q3ZBE7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10079319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10079389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10064743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10064749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10092210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10092212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10081949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10081955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10057046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10057060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10065129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02070", "target": "species_10065161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057323", "target": "P02070" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10079199", "target": "species_10079197" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10079131", "target": "reaction_10079199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB1", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIB1", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013018", "target": "A0A452DIB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDR7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDR7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDR7", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDR7", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003865", "target": "F1MDR7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK38", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK38", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK38", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK38", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061018", "target": "E1BK38" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11023", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11023", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014062", "target": "P11023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNI4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNI4", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018777", "target": "F1MNI4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK4", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCK4", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054453", "target": "F1MCK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q673L2", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q673L2", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027807", "target": "Q673L2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10061500" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10067227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10067218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10066878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI99", "target": "species_10065411" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071484", "target": "Q2KI99" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071484", "target": "species_10066530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071484", "target": "species_10061498" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDL5", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDL5", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDL5", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDL5", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086325", "target": "A0A3Q1NDL5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6D0", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6D0", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6D0", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6D0", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004058", "target": "G3X6D0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBS7", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBS7", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBS7", "target": "species_10083720" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBS7", "target": "species_10084244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082349", "target": "A0A3Q1MBS7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL8", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPL8", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002681", "target": "E1BPL8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10085162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10083333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIE6", "target": "species_10083323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037678", "target": "F1MIE6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJS9", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJS9", "target": "species_10079197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJS9", "target": "species_10045234" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013320", "target": "F1MJS9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013320", "target": "species_10045228" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB09", "target": "species_10079131" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB09", "target": "species_10079197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068383", "target": "A0A3Q1MB09" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078929", "target": "species_10078927" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078881", "target": "reaction_10078929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIW2", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIW2", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000146", "target": "Q2KIW2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Q9", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0Q9", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015396", "target": "Q3T0Q9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY77", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY77", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065645", "target": "G3MY77" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065645", "target": "species_10071487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJY9", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJY9", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJY9", "target": "species_10071340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJY9", "target": "species_10071342" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020644", "target": "A5PJY9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NHB1", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NHB1", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080189", "target": "A0A3Q1NHB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II86", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II86", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II86", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II86", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027666", "target": "Q0II86" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTK4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTK4", "target": "species_10078927" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTK4", "target": "species_10035783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTK4", "target": "species_10085794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTK4", "target": "species_10058806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001250", "target": "F1MTK4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001250", "target": "species_10035781" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDS4", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDS4", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073232", "target": "A0A3Q1MDS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAZ1", "target": "species_10078881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAZ1", "target": "species_10078927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071382", "target": "A0A3Q1MAZ1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081265", "target": "species_10081263" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081245", "target": "reaction_10081265" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNS8", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNS8", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061310", "target": "F1MNS8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0V2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065029", "target": "G3N0V2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RY7", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RY7", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012815", "target": "Q29RY7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFQ6", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFQ6", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018403", "target": "A4IFQ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07688", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07688", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036795", "target": "P07688" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB52", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB52", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB52", "target": "species_10078472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002003", "target": "E1BB52" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002003", "target": "species_10078470" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ01", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ01", "target": "species_10081263" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011678", "target": "A0A452DJ01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXZ0", "target": "species_10081245" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXZ0", "target": "species_10081263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXZ0", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXZ0", "target": "species_10080433" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080435", "target": "species_10080433" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080307", "target": "reaction_10080435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGY9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGY9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022716", "target": "F1MGY9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPJ7", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPJ7", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067144", "target": "A0A3Q1MPJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBA2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006754", "target": "A7MBA2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPT4", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPT4", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPT4", "target": "species_10077916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPT4", "target": "species_10077914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067752", "target": "A6QPT4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77834", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77834", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77834", "target": "species_10067741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006383", "target": "O77834" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYV0", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYV0", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070714", "target": "A0A3Q1LYV0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLB7", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLB7", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017775", "target": "A6QLB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH5", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBH5", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013796", "target": "Q3ZBH5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM5", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHM5", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074704", "target": "Q3MHM5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUG9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUG9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076880", "target": "A0A3Q1LUG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46415", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46415", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O46415", "target": "species_10059178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009965", "target": "O46415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7I6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7I6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024550", "target": "F1N7I6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1V6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1V6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005121", "target": "F1N1V6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU24", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU24", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006069", "target": "F1MU24" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJD0", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJD0", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009158", "target": "Q2KJD0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQA6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQA6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072426", "target": "A0A3Q1LQA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFP1", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000304", "target": "E1BFP1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK8", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK8", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK8", "target": "species_10083102" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK8", "target": "species_10083104" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064845", "target": "G3MXK8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064845", "target": "species_10080371" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ81", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ81", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034528", "target": "A6QQ81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ87", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ87", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039203", "target": "A0A452DJ87" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064726", "target": "A6QNX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEU9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEU9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066561", "target": "A0A3Q1NEU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKA9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKA9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084208", "target": "A0A3Q1LKA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML33", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML33", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073654", "target": "A0A3Q1ML33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMW6", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMW6", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073103", "target": "A0A3Q1LMW6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B5", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8B5", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053165", "target": "E1B8B5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTS9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTS9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068563", "target": "A0A3Q1LTS9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS7", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS7", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065330", "target": "F1MMS7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY36", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY36", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068245", "target": "A0A3Q1LY36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X8C3", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X8C3", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055709", "target": "G3X8C3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW8", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW8", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW8", "target": "species_10081428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW8", "target": "species_10081430" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW8", "target": "species_10087599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073870", "target": "A0A3Q1LIW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79345", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79345", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79345", "target": "species_10085992" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029271", "target": "P79345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029271", "target": "species_10085990" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUP9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUP9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009715", "target": "F1MUP9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGC2", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGC2", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036230", "target": "F1MGC2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2H4", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2H4", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063121", "target": "G3N2H4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIT9", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIT9", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019270", "target": "F6QIT9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04272", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04272", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P04272", "target": "species_10038283" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012655", "target": "P04272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS42", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS42", "target": "species_10080433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074408", "target": "A0A3Q1MS42" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGT8", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGT8", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGT8", "target": "species_10078755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGT8", "target": "species_10078757" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083141", "target": "A0A3Q1LGT8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA1", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA1", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA1", "target": "species_10078755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKA1", "target": "species_10078757" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046857", "target": "E1BKA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28050", "target": "species_10080307" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28050", "target": "species_10080433" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28050", "target": "species_10078755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28050", "target": "species_10078757" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010838", "target": "Q28050" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10079653", "target": "species_10079651" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10079613", "target": "reaction_10079653" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LK2", "target": "species_10079613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LK2", "target": "species_10079651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022077", "target": "Q32LK2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072392", "target": "species_10072390" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072358", "target": "reaction_10072392" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072390" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072360" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072362" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072378" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28808", "target": "species_10072385" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072390", "target": "reaction_10072395" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072395", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072395", "target": "species_10072360" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084636", "target": "species_10084634" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084632", "target": "reaction_10084636" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084616", "target": "reaction_10084636" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054378", "target": "species_10084616" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054378", "target": "E1BJL5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL5", "target": "species_10084634" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072364", "target": "species_10072360" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072364", "target": "species_10072008" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072362", "target": "reaction_10072364" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072008", "target": "reaction_10072011" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072383", "target": "species_10072358" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072383", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072378", "target": "reaction_10072383" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072380", "target": "reaction_10072383" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072388", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072388", "target": "species_10072362" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072385", "target": "reaction_10072388" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072374", "target": "species_10072372" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072370", "target": "reaction_10072374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5621138", "target": "reaction_10072374" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5621138", "target": "species_10072372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072057", "target": "species_10071998" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072055", "target": "reaction_10072057" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074019", "target": "species_10072055" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074019", "target": "species_10071996" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074019", "target": "A0A3Q1LKU2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074019", "target": "species_10072017" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071996", "target": "reaction_10072057" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071998", "target": "reaction_10072002" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKU2", "target": "species_10071998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKU2", "target": "species_10072000" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKU2", "target": "species_10072013" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKU2", "target": "species_10072049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKU2", "target": "species_10072051" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072011", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072011", "target": "species_112275" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072045", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072045", "target": "species_10072043" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072038", "target": "reaction_10072045" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37671", "target": "species_10072038" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:37671", "target": "species_10072043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2F3", "target": "species_10072038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2F3", "target": "species_10072043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085840", "target": "F1N2F3" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072061", "target": "species_10072008" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072059", "target": "reaction_10072061" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072015", "target": "species_10072013" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072000", "target": "reaction_10072015" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072032", "target": "species_10072019" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072004", "target": "reaction_10072032" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072019", "target": "reaction_10072022" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072002", "target": "species_10072000" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072053", "target": "species_10072051" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072049", "target": "reaction_10072053" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072006", "target": "species_10072004" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070610", "target": "reaction_10072006" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072022", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072022", "target": "species_10071996" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072017", "target": "reaction_10072022" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054649", "target": "species_10054647" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054645", "target": "reaction_10054649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N570", "target": "species_10054645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N570", "target": "species_10054647" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073079", "target": "A0A3Q1N570" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073079", "target": "species_10054624" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054492", "target": "reaction_10054649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF14", "target": "species_10054492" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MF14", "target": "species_10054647" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076236", "target": "A0A3Q1MF14" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076236", "target": "species_10054490" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076236", "target": "species_10054488" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054647", "target": "reaction_10054678" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054494", "target": "species_10054492" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054490", "target": "reaction_10054494" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054488", "target": "reaction_10054494" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066238", "target": "species_10066236" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039322", "target": "reaction_10066238" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039322", "target": "reaction_10054736" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090400", "target": "species_10084063" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084018", "target": "reaction_10090400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIV9", "target": "species_10039776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014871", "target": "Q2KIV9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3B0IZF8", "target": "species_10039776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014865", "target": "A0A3B0IZF8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10039765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9E3", "target": "species_10039776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040146", "target": "Q5E9E3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGP1", "target": "species_10084018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGP1", "target": "species_10084063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGP1", "target": "species_10039462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGP1", "target": "species_10039759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGP1", "target": "species_10039765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073935", "target": "A0A3Q1MGP1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055971", "target": "species_10055969" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_1006146", "target": "reaction_10055971" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054484", "target": "reaction_10055971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSC6", "target": "species_10054484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSC6", "target": "species_10055969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069343", "target": "A0A3Q1LSC6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC45", "target": "species_10054484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC45", "target": "species_10055969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029340", "target": "F1MC45" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087797", "target": "species_10054645" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054643", "target": "reaction_10087797" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054624", "target": "reaction_10087797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084020", "target": "species_10084018" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039462", "target": "reaction_10084020" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039462", "target": "reaction_10039465" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054678", "target": "species_10054675" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10054678", "target": "species_10054624" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054678", "target": "species_10054657" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054678", "target": "species_10054492" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039465", "target": "species_10039310" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039465", "target": "species_10039322" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039302", "target": "reaction_10039465" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039778", "target": "species_10039765" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039759", "target": "reaction_10039778" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039765", "target": "reaction_10039782" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039776", "target": "reaction_10039778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "C4T8B4", "target": "species_10039776" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018469", "target": "C4T8B4" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1524071", "target": "species_10039776" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524071", "target": "reaction_10059094" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039782", "target": "species_10039462" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054736", "target": "species_10054643" }, { "type": "reactant", "sub_type": "", "source": "species_983438", "target": "reaction_10054736" }, { "type": "reactant", "sub_type": "", "source": "species_983438", "target": "reaction_10077926" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053134", "target": "species_10053132" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053126", "target": "reaction_10053134" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053126", "target": "reaction_10092318" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085261", "target": "species_10053126" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085261", "target": "A0A3Q1MIH6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053130", "target": "reaction_10053134" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016601", "target": "species_10053130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016601", "target": "F1MUU5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUU5", "target": "species_10053132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIH6", "target": "species_10053132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIH6", "target": "species_10092316" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053122", "target": "species_10053120" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053118", "target": "reaction_10053122" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053095", "target": "species_10053093" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053091", "target": "reaction_10053095" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053086", "target": "reaction_10053095" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053086", "target": "reaction_10086155" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056088", "target": "species_10056086" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056080", "target": "reaction_10056088" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053054", "target": "reaction_10056088" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053054", "target": "reaction_10053058" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053054", "target": "reaction_10056084" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053058", "target": "species_10053056" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092318", "target": "species_10092316" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070254", "target": "reaction_10092318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056090", "target": "species_10039556" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056090", "target": "species_10039554" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056090", "target": "species_10056078" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039556", "target": "reaction_10056082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039556", "target": "reaction_10063376" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056078", "target": "reaction_10056082" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056082", "target": "species_10056080" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056082", "target": "species_10040193" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056082", "target": "species_10040189" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040189", "target": "reaction_10056084" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056084", "target": "species_10056076" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066559", "target": "species_10066557" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066555", "target": "reaction_10066559" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008082", "target": "species_10066555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008082", "target": "Q05B79" }, { "type": "reactant", "sub_type": "", "source": "species_3134861", "target": "reaction_10066559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B79", "target": "species_10066557" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090837", "target": "species_10040193" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066536", "target": "species_10066530" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066536", "target": "species_10055114" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061500", "target": "reaction_10066536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCP5", "target": "species_10061500" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022801", "target": "Q0VCP5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022801", "target": "species_10055114" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066530", "target": "reaction_10066532" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055114", "target": "reaction_10061502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061502", "target": "species_10061500" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061498", "target": "reaction_10061502" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061498", "target": "reaction_10066532" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066551", "target": "species_10066548" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10054900", "target": "reaction_10066551" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066540", "target": "reaction_10066551" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066540", "target": "reaction_10090019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043510", "target": "species_10066540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043510", "target": "A3KN07" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN07", "target": "species_10066548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN07", "target": "species_10090017" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066608", "target": "species_10066606" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_874088", "target": "reaction_10066608" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_874088", "target": "species_10066606" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066604", "target": "reaction_10066608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011748", "target": "species_10066604" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011748", "target": "E1BIN9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011748", "target": "species_10035708" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10066606" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10076295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10035718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10068852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10075051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10035710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN9", "target": "species_10074665" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065388", "target": "species_10039556" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039546", "target": "reaction_10065388" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063376", "target": "species_10040189" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067225", "target": "species_10067210" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067208", "target": "reaction_10067225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067210", "target": "reaction_10067216" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067229", "target": "species_10067227" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10046560", "target": "reaction_10067229" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065393", "target": "reaction_10067229" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067227", "target": "reaction_10067233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKP4", "target": "species_10067227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKP4", "target": "species_10067218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKP4", "target": "species_10065404" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKP4", "target": "species_10065395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKP4", "target": "species_10065400" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067231", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067231", "target": "species_10067208" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067220", "target": "reaction_10067231" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067233", "target": "species_10067218" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067233", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067218", "target": "reaction_10067223" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067216", "target": "species_10067214" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067223", "target": "species_10067220" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067223", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067223", "target": "species_10065404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065402", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065402", "target": "species_10065400" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065395", "target": "reaction_10065402" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065400", "target": "reaction_10065407" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065407", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065407", "target": "species_10065404" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065407", "target": "species_10039546" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066880", "target": "species_10066878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3244587", "target": "reaction_10066880" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3244587", "target": "species_10066878" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065409", "target": "reaction_10066880" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065409", "target": "reaction_10065413" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090019", "target": "species_10090017" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8982080", "target": "reaction_10090019" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2395973", "target": "species_8982080" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2395973", "target": "species_10090017" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395973", "target": "reaction_10065413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2395973", "target": "species_10065411" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:47037", "target": "species_8982080" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:47037", "target": "species_10090017" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065413", "target": "species_10065411" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066532", "target": "species_10065409" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081432", "target": "species_10081430" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081428", "target": "reaction_10081432" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081428", "target": "reaction_10087601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08904", "target": "species_10081428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08904", "target": "species_10081430" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08904", "target": "species_10087599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011585", "target": "P08904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZA1", "target": "species_10081428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZA1", "target": "species_10081430" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZA1", "target": "species_10087599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065979", "target": "G3MZA1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6803074", "target": "reaction_10081432" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55478", "target": "species_6803074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55478", "target": "species_10081430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_6803074" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_10081430" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6789198", "target": "reaction_10084683" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_10084681" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_10080839" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6789198", "target": "reaction_10080844" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6789198", "target": "reaction_10081410" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_10081408" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6789198", "target": "reaction_10080831" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6789198", "target": "species_10080829" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10082008", "target": "species_10082006" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081939", "target": "reaction_10082008" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081939", "target": "reaction_10081943" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083501", "target": "species_10081939" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083501", "target": "species_10082006" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083501", "target": "A0A3Q1LWA5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082006", "target": "reaction_10082012" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056539", "target": "species_10056537" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056535", "target": "reaction_10056539" }, { "type": "reactant", "sub_type": "", "source": "species_8879165", "target": "reaction_10056539" }, { "type": "reactant", "sub_type": "", "source": "species_8879165", "target": "reaction_10082967" }, { "type": "reactant", "sub_type": "", "source": "species_8879165", "target": "reaction_10082183" }, { "type": "reactant", "sub_type": "", "source": "species_8879165", "target": "reaction_10083106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082012", "target": "species_10082010" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10082012" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10083100" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10082004" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10081943" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10081406" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10087601" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8931784", "target": "reaction_10084706" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA5", "target": "species_10082010" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWA5", "target": "species_10081941" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083100", "target": "species_10083098" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083096", "target": "reaction_10083100" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025186", "target": "species_10083096" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025186", "target": "Q95JC3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95JC3", "target": "species_10083098" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070906", "target": "species_10070904" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070902", "target": "reaction_10070906" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17189", "target": "species_10070902" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17189", "target": "species_10070904" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_912516", "target": "reaction_10070906" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_912516", "target": "reaction_10052866" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_912516", "target": "reaction_10052916" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10070904" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10056414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10052876" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10052886" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10052874" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_917966", "target": "reaction_10052901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917966", "target": "species_10085162" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056416", "target": "species_10056414" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2101051", "target": "reaction_10056416" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2101051", "target": "species_10056414" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056412", "target": "reaction_10056416" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222611", "target": "reaction_10056416" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078759", "target": "species_10078757" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078755", "target": "reaction_10078759" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082004", "target": "species_10082002" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081994", "target": "reaction_10082004" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077381", "target": "species_10081994" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077381", "target": "A0A3Q1LX31" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX31", "target": "species_10082002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081559", "target": "species_10081557" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081555", "target": "reaction_10081559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3R4", "target": "species_10081555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3R4", "target": "species_10081557" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064812", "target": "G3N3R4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6804535", "target": "reaction_10081559" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42976", "target": "species_6804535" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42976", "target": "species_10081557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59496", "target": "species_6804535" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:59496", "target": "species_10081557" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:85986", "target": "species_6804535" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:85986", "target": "species_10081557" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081943", "target": "species_10081941" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082967", "target": "species_10082965" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082963", "target": "reaction_10082967" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME64", "target": "species_10082963" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ME64", "target": "species_10082965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078640", "target": "A0A3Q1ME64" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084683", "target": "species_10084681" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10079373", "target": "reaction_10084683" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084681", "target": "reaction_10084686" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080842", "target": "species_10080837" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080842", "target": "species_6799970" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080842", "target": "species_6799975" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080839", "target": "reaction_10080842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH94", "target": "species_10080839" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BH94", "target": "species_10080837" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047024", "target": "E1BH94" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080837", "target": "reaction_10080842" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080837", "target": "reaction_10080844" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28881", "target": "species_6799970" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080844", "target": "species_10080839" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084686", "target": "species_6788991" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084686", "target": "species_6788982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:21615", "target": "species_6788991" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058388", "target": "species_10058386" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058328", "target": "reaction_10058388" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081410", "target": "species_10081408" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081389", "target": "reaction_10081410" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081389", "target": "reaction_10081406" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086119", "target": "species_10081389" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086119", "target": "P23132" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086119", "target": "species_10081399" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086119", "target": "species_10081401" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23132", "target": "species_10081408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23132", "target": "species_10081391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P23132", "target": "species_10081395" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082183", "target": "species_10082181" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082179", "target": "reaction_10082183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLW2", "target": "species_10082179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLW2", "target": "species_10082181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020875", "target": "F1MLW2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHQ2", "target": "species_10082179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHQ2", "target": "species_10082181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012052", "target": "F1MHQ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMF1", "target": "species_10082179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RMF1", "target": "species_10082181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044454", "target": "F6RMF1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081404", "target": "species_10081389" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081404", "target": "species_10081401" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081399", "target": "reaction_10081404" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058556", "target": "reaction_10081404" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080831", "target": "species_10080829" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080827", "target": "reaction_10080831" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1U5", "target": "species_10080827" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1U5", "target": "species_10080829" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078335", "target": "A0A3Q1M1U5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081406", "target": "species_10081391" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081391", "target": "reaction_10081397" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087601", "target": "species_10087599" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081397", "target": "species_10081395" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081385", "target": "species_10056535" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081382", "target": "reaction_10081385" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10080371", "target": "reaction_10081385" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082977", "target": "species_10082975" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6803081", "target": "reaction_10082977" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082971", "target": "reaction_10082977" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056512", "target": "species_10082971" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056512", "target": "A1A4Q6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4Q6", "target": "species_10082975" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083106", "target": "species_10083104" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083102", "target": "reaction_10083106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084706", "target": "species_10084704" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10059808", "target": "reaction_10084706" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051836", "target": "species_10051834" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051824", "target": "reaction_10051836" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q8", "target": "species_10051824" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q8", "target": "species_10051834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085633", "target": "A0A3Q1M2Q8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051832", "target": "reaction_10051836" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8Q0", "target": "species_10051832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8Q0", "target": "species_10051834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066698", "target": "A0A3Q1N8Q0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077919", "target": "species_1222475" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077919", "target": "species_6789150" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222719", "target": "reaction_10077919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222719", "target": "reaction_10086405" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222719", "target": "reaction_10077924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6788973", "target": "reaction_10077919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6788973", "target": "reaction_10077924" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1470067", "target": "reaction_10077919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1470067", "target": "reaction_10086405" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1470067", "target": "reaction_10077924" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077916", "target": "reaction_10077919" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55376", "target": "species_10077916" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55376", "target": "species_10084319" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55376", "target": "species_10077914" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084322", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084322", "target": "species_8855489" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8855492", "target": "reaction_10084322" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084319", "target": "reaction_10084322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80025", "target": "species_10084319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016986", "target": "P80025" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086405", "target": "species_8933637" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086405", "target": "species_1222475" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6789221", "target": "reaction_10086405" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077914", "target": "reaction_10086405" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077914", "target": "reaction_10077924" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077914", "target": "reaction_10077926" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077924", "target": "species_1222475" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077924", "target": "species_6789150" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077926", "target": "species_10077916" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077921", "target": "species_1222461" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077921", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077921", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222561", "target": "reaction_10077921" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077904", "target": "species_1470067" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077901", "target": "reaction_10077904" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047907", "target": "species_202124" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047907", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047907", "target": "species_29968" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047904", "target": "reaction_10047907" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069366", "target": "species_10047904" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056531", "target": "species_1470067" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056528", "target": "reaction_10056531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28029", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009961", "target": "Q28029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79251", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000240", "target": "P79251" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCV6", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019267", "target": "Q0VCV6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMV6", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026498", "target": "E1BMV6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P31408", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024812", "target": "P31408" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3I3", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073116", "target": "A0A3Q1M3I3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LB7", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018250", "target": "Q32LB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21282", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017968", "target": "P21282" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFJ9", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032875", "target": "A4IFJ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P81103", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020094", "target": "P81103" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10056528" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091329" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091358" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI38", "target": "species_10091362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007912", "target": "A0A452DI38" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O97681", "target": "species_10056528" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009563", "target": "O97681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ7", "target": "species_10056528" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005588", "target": "E1BGJ7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063368", "target": "species_264618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063368", "target": "species_1602448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1602448", "target": "reaction_10077777" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1602448", "target": "reaction_10059860" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1602448", "target": "reaction_10085340" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10063365", "target": "reaction_10063368" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049304", "target": "species_10049302" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043043", "target": "reaction_10049304" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043043", "target": "reaction_10043049" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082561", "target": "species_10043043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082561", "target": "A0A3Q1MRS3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082561", "target": "species_10043047" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082561", "target": "species_10043045" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044490", "target": "reaction_10049304" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044490", "target": "reaction_10044515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRM3", "target": "species_10044490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRM3", "target": "species_10049302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRM3", "target": "species_10044513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075471", "target": "A0A3Q1MRM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8K4", "target": "species_10044490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8K4", "target": "species_10049302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8K4", "target": "species_10044513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085126", "target": "A0A3Q1M8K4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRS3", "target": "species_10049302" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075165", "target": "species_10075163" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075149", "target": "reaction_10075165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N153", "target": "species_10075149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N153", "target": "species_10075163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N153", "target": "species_10075139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N153", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065898", "target": "G3N153" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8J2", "target": "species_10075149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8J2", "target": "species_10075163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8J2", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053203", "target": "E1B8J2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053203", "target": "species_10075143" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075161", "target": "reaction_10075165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PI0", "target": "species_10075161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PI0", "target": "species_10075163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PI0", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011384", "target": "Q32PI0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7Q0", "target": "species_10075161" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7Q0", "target": "species_10075163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7Q0", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005923", "target": "F1N7Q0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075163", "target": "reaction_10077625" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075151", "target": "species_10075149" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075143", "target": "reaction_10075151" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075139", "target": "reaction_10075151" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050458", "target": "species_10050456" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050452", "target": "reaction_10050458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE67", "target": "species_10050452" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE67", "target": "species_10050456" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023167", "target": "A2VE67" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040857", "target": "species_10040800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040855", "target": "reaction_10040857" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040800" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040952" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P18246", "target": "species_10040965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002398", "target": "P18246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002398", "target": "species_10040862" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040800", "target": "reaction_10040842" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040842", "target": "species_10040840" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036729", "target": "species_10036726" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036729", "target": "species_29554" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036724", "target": "reaction_10036729" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUX1", "target": "species_10036724" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUX1", "target": "species_10036726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUX1", "target": "species_10036733" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028844", "target": "F1MUX1" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29554", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29554", "target": "species_179742" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036716", "target": "species_29692" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036716", "target": "species_10036706" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036713", "target": "reaction_10036716" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29692", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29692", "target": "species_179742" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036767", "target": "species_10036757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036767", "target": "species_5636006" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036764", "target": "reaction_10036767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPV2", "target": "species_10036764" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPV2", "target": "species_10036757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPV2", "target": "species_10036755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010226", "target": "F1MPV2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010226", "target": "species_10091562" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010226", "target": "species_10091564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036736", "target": "species_10036726" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036736", "target": "species_29692" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036733", "target": "reaction_10036736" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036709", "target": "species_10036706" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036709", "target": "species_29554" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036702", "target": "reaction_10036709" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036743", "target": "species_10036706" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036743", "target": "species_110233" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036740", "target": "reaction_10036743" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089640", "target": "species_10086640" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089640", "target": "species_113541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089633", "target": "reaction_10089640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10089633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10089605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10087908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10087995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10087887" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10087897" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10084945" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10088001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10088003" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9S8", "target": "species_10086499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021434", "target": "E1B9S8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021434", "target": "species_10084939" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10089633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10086640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10086714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10089672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10089605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKY5", "target": "species_10089355" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066565", "target": "A0A3Q1MKY5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066565", "target": "species_10086213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066565", "target": "species_10089674" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066565", "target": "species_10089668" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066565", "target": "species_10086719" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086640", "target": "reaction_10089610" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089637", "target": "reaction_10089640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012404", "target": "species_10089637" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086716", "target": "species_10086714" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086213", "target": "reaction_10086716" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086213", "target": "reaction_10089357" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086712", "target": "reaction_10086716" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086712", "target": "reaction_10092289" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086714", "target": "reaction_10086724" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089679", "target": "species_10055082" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10089679", "target": "species_10089674" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089672", "target": "reaction_10089679" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055082", "target": "reaction_10089681" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089681", "target": "species_10089672" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089668", "target": "reaction_10089681" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086724", "target": "species_10086719" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086724", "target": "species_10086712" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089610", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089610", "target": "species_10089605" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089607", "target": "reaction_10089610" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089357", "target": "species_10089355" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089353", "target": "reaction_10089357" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084141", "target": "species_10089353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084141", "target": "A0A3Q1MN22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN22", "target": "species_10089355" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074877", "target": "species_10074875" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055523", "target": "reaction_10074877" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055523", "target": "reaction_10055649" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020012", "target": "species_10055523" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020012", "target": "F1MW99" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074873", "target": "reaction_10074877" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013145", "target": "species_10074873" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013145", "target": "A0A452DJ33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ33", "target": "species_10074875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW99", "target": "species_10074875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW99", "target": "species_10055525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW99", "target": "species_10055527" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065177", "target": "species_10065175" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064869", "target": "reaction_10065177" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064869", "target": "reaction_10065563" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10064869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMZ9", "target": "species_10065792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007705", "target": "E1BMZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPS0", "target": "species_10064869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPS0", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPS0", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPS0", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPS0", "target": "species_10065198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039478", "target": "F1MPS0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N535", "target": "species_10064869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N535", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N535", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N535", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N535", "target": "species_10065198" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021476", "target": "F1N535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10064869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY41", "target": "species_10065792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011562", "target": "F1MY41" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064891", "target": "reaction_10065177" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064904", "target": "species_10064901" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064904", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064904", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064904", "target": "species_159939" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064897", "target": "reaction_10064904" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065563", "target": "species_10065561" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065559", "target": "reaction_10065563" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068774", "target": "species_10065559" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068774", "target": "A0A3Q1M8A5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050283", "target": "reaction_10065563" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050283", "target": "reaction_10050306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR3", "target": "species_10050283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR3", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR3", "target": "species_10050304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027913", "target": "Q2TBR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQB1", "target": "species_10050283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQB1", "target": "species_10065561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQB1", "target": "species_10050304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030281", "target": "A0A3Q1MQB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8A5", "target": "species_10065561" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065201", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065201", "target": "species_10065198" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065186", "target": "reaction_10065201" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064733", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064733", "target": "species_10064723" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064715", "target": "reaction_10064733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDP8", "target": "species_10064715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NDP8", "target": "species_10064723" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075206", "target": "A0A3Q1NDP8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075206", "target": "A0A3Q1M3X4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3X4", "target": "species_10064715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3X4", "target": "species_10064723" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064730", "target": "reaction_10064733" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064730", "target": "reaction_10065572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022950", "target": "species_10064730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065572", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065572", "target": "species_10065570" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065567", "target": "reaction_10065572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009379", "target": "species_10065567" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009379", "target": "species_10065570" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066345", "target": "species_10066342" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066345", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066322", "target": "reaction_10066345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM88", "target": "species_10066322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM88", "target": "species_10066342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM88", "target": "species_10066320" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022098", "target": "F1MM88" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7J4", "target": "species_10066322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7J4", "target": "species_10066342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7J4", "target": "species_10066309" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070292", "target": "A6H7J4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066324", "target": "species_10066322" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066309", "target": "reaction_10066324" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066320", "target": "reaction_10066324" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070705", "target": "species_113550" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070705", "target": "species_5221124" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5221122", "target": "reaction_10070705" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069478", "target": "reaction_10070705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069491", "target": "species_113550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069491", "target": "species_10069478" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069470", "target": "reaction_10069491" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069488", "target": "reaction_10069491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMV9", "target": "species_10069488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025896", "target": "Q1RMV9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBP2", "target": "species_10069488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046962", "target": "Q3ZBP2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065095", "target": "species_10065092" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065095", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065087", "target": "reaction_10065095" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038371", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038371", "target": "species_159564" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159447", "target": "reaction_10038371" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038368", "target": "reaction_10038371" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038368", "target": "reaction_10038382" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBJ0", "target": "species_10038368" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077055", "target": "A0A3Q1MBJ0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038354", "target": "species_159448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038354", "target": "species_159450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038354", "target": "species_159447" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159446", "target": "reaction_10038354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159448", "target": "reaction_10056002" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038351", "target": "reaction_10038354" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038351", "target": "reaction_10040185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025874", "target": "species_10038351" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025874", "target": "A7MBE6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039520", "target": "species_10037620" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037233", "target": "reaction_10039520" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037233", "target": "reaction_10037237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037620", "target": "reaction_10037622" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QH5", "target": "species_10037620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QH5", "target": "species_10037275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QH5", "target": "species_10051167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QH5", "target": "species_10051173" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037237", "target": "species_10037235" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037622", "target": "species_10037269" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037622", "target": "species_10037233" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047809", "target": "species_10046044" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058908", "target": "species_1500604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058908", "target": "species_1524021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426755", "target": "reaction_10058908" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426755", "target": "reaction_10058896" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426755", "target": "reaction_10059141" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426755", "target": "reaction_10059091" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500604", "target": "reaction_10035786" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077777", "target": "species_1602447" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077777", "target": "species_1602366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077774", "target": "reaction_10077777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MMR4", "target": "species_10077774" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085985", "target": "A0A3Q1MMR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSS2", "target": "species_10077774" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017473", "target": "F1MSS2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058896", "target": "species_1500604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058896", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058855", "target": "reaction_10058896" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058855", "target": "reaction_10058858" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058855", "target": "reaction_10059016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058834", "target": "species_1500590" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058834", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500580", "target": "reaction_10058834" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058831", "target": "reaction_10058834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006476", "target": "species_10058831" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006476", "target": "A0A3S5ZPU2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059860", "target": "species_1602447" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059860", "target": "species_1602366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088649", "target": "species_8954401" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088649", "target": "species_1500590" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189422", "target": "reaction_10088649" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088630", "target": "reaction_10088649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE10", "target": "species_10088630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010531", "target": "E1BE10" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088647", "target": "reaction_10088649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNB3", "target": "species_10088647" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043938", "target": "F1MNB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JPG0", "target": "species_10088647" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014090", "target": "Q1JPG0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086248", "target": "species_8878776" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086248", "target": "species_109277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8878780", "target": "reaction_10086248" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086245", "target": "reaction_10086248" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2M5", "target": "species_10086245" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043359", "target": "F1N2M5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058923", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058923", "target": "species_1500580" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058920", "target": "reaction_10058923" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015359", "target": "species_10058920" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035786", "target": "species_426755" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035786", "target": "species_76194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035783", "target": "reaction_10035786" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95JH2", "target": "species_10035783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083979", "target": "Q95JH2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083979", "target": "species_10035753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7D4", "target": "species_10035783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007532", "target": "A6H7D4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007532", "target": "species_10035769" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJ33", "target": "species_10035783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076188", "target": "A0A3Q1LJ33" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076188", "target": "species_10035773" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5P6", "target": "species_10035783" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGF8", "target": "species_10035783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023396", "target": "E1BGF8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPU2", "target": "species_10035783" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058858", "target": "species_1500580" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058858", "target": "species_1524103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059114", "target": "species_264618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059114", "target": "species_426755" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059111", "target": "reaction_10059114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051264", "target": "species_1500604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051264", "target": "species_76194" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035769", "target": "reaction_10051264" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035812", "target": "species_76114" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035812", "target": "species_29360" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035809", "target": "reaction_10035812" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJJ3", "target": "species_10035809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021683", "target": "A0A452DJJ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUU4", "target": "species_10035809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057343", "target": "A0A3Q1MUU4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044235", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044235", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044235", "target": "species_213144" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30321", "target": "reaction_10044235" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30321", "target": "reaction_10044182" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044177", "target": "reaction_10044235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ03", "target": "species_10044177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ03", "target": "species_10044474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ03", "target": "species_10044179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ03", "target": "species_10071719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ03", "target": "species_10038057" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067793", "target": "A0A3Q1LZ03" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10044177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10044474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10044220" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10044179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10090495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10071719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10038057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6I4", "target": "species_10071724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016177", "target": "G3X6I4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016177", "target": "Q29RV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RV2", "target": "species_10044177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RV2", "target": "species_10044474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RV2", "target": "species_10044179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RV2", "target": "species_10071719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RV2", "target": "species_10038057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T047", "target": "species_10044177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T047", "target": "species_10044474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T047", "target": "species_10044179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T047", "target": "species_10071719" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T047", "target": "species_10038057" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063483", "target": "Q3T047" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044255", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044255", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044255", "target": "species_216598" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_216547", "target": "reaction_10044255" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044252", "target": "reaction_10044255" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXW1", "target": "species_10044252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023544", "target": "F1MXW1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044158", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044158", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044158", "target": "species_215584" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044155", "target": "reaction_10044158" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024282", "target": "species_10044155" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044242", "target": "species_216620" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044242", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044242", "target": "species_113564" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044239", "target": "reaction_10044242" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044247", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044247", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044247", "target": "species_216612" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_216621", "target": "reaction_10044247" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044244", "target": "reaction_10044247" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078408", "target": "species_10078406" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066675", "target": "reaction_10078408" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066675", "target": "reaction_10084047" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066675", "target": "reaction_10066684" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033535", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033535", "target": "species_10033524" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033519", "target": "reaction_10033535" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033519", "target": "reaction_10081602" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10081470" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10066745" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10078731" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10066670" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10083072" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10081541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10081877" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10066724" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10081530" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033524", "target": "reaction_10081522" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033532", "target": "reaction_10033535" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006518", "target": "species_10033532" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006518", "target": "species_10074688" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006518", "target": "F6R5E4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076341", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076341", "target": "species_10033519" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10076341" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10081563" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10081595" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10080730" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10081629" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10066870" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10081622" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066677", "target": "reaction_10088012" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081470", "target": "species_10081468" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081466", "target": "reaction_10081470" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070196", "target": "species_10081466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070196", "target": "A0A3Q1M6W9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6W9", "target": "species_10081468" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057800", "target": "species_10057798" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057796", "target": "reaction_10057800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057796", "target": "reaction_10057804" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057796", "target": "reaction_10057808" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057796", "target": "reaction_10057812" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9Y0", "target": "species_10057796" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9Y0", "target": "species_10057798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9Y0", "target": "species_10057802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9Y0", "target": "species_10057806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9Y0", "target": "species_10057810" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005252", "target": "Q5E9Y0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056559", "target": "reaction_10057800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056559", "target": "reaction_10056602" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10056559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10057798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10056608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10057806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10056566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKK9", "target": "species_10088582" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076561", "target": "A0A3Q1MKK9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076561", "target": "species_10056555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10056559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10057798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10056608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10057806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10056566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10088552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10088562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10089570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QZ4", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084839", "target": "Q17QZ4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084839", "target": "species_10056551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1Y7", "target": "species_10056559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1Y7", "target": "species_10057798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1Y7", "target": "species_10057802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1Y7", "target": "species_10057814" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1Y7", "target": "species_10057818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084739", "target": "A0A3Q1M1Y7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084739", "target": "species_10056543" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084739", "target": "species_10056564" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBE6", "target": "species_10056559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBE6", "target": "species_10057798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBE6", "target": "species_10056608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBE6", "target": "species_10057806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBE6", "target": "species_10056566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015999", "target": "F1MBE6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057804", "target": "species_10057802" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056543", "target": "reaction_10057804" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057808", "target": "species_10057806" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056608", "target": "reaction_10057808" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10056608", "target": "reaction_10056616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMR3", "target": "species_10056608" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMR3", "target": "species_10057806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMR3", "target": "species_10057810" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015333", "target": "E1BMR3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015333", "target": "species_10056606" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015333", "target": "species_10056614" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057812", "target": "species_10057810" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056606", "target": "reaction_10057812" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037433", "target": "species_10037431" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037433", "target": "species_29420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037427", "target": "reaction_10037433" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037342", "target": "reaction_10037433" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037342", "target": "reaction_10037353" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037353", "target": "species_10037350" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037353", "target": "species_29420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037346", "target": "reaction_10037353" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047880", "target": "species_10047878" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10047872", "target": "reaction_10047880" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092299", "target": "species_10047872" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092299", "target": "species_10092297" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092295", "target": "reaction_10092299" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037580", "target": "species_10037569" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037580", "target": "species_10037342" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037563", "target": "reaction_10037580" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047886", "target": "species_10047884" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047884", "target": "reaction_10047886" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041337", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041337", "target": "species_193747" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041337", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193785", "target": "reaction_10041337" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041337" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041339" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041363" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041367" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041359" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041345" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041206" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041179" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041310" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041104" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041172" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041325" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041101", "target": "reaction_10041327" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017935", "target": "species_10041101" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041339", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041339", "target": "species_193716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041339", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193708", "target": "reaction_10041339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193716", "target": "reaction_10041345" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041341", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041341", "target": "species_193741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041341", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041341", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193762", "target": "reaction_10041341" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193762", "target": "reaction_10041357" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041314", "target": "reaction_10041341" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041314", "target": "reaction_10041347" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041314", "target": "reaction_10041321" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041314", "target": "reaction_10041317" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041343", "target": "species_193732" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193732", "target": "reaction_10041343" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041361", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041361", "target": "species_193728" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193707", "target": "reaction_10041361" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041361" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041353" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041369" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041377" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041210" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041167", "target": "reaction_10041170" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041363", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041363", "target": "species_193782" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041363", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193777", "target": "reaction_10041363" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193782", "target": "reaction_10041359" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041365", "target": "species_193724" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041365", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041365", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192189", "target": "reaction_10041365" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193724", "target": "reaction_10041349" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041201", "target": "reaction_10041365" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041201", "target": "reaction_10041371" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041201", "target": "reaction_10041204" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003028", "target": "species_10041201" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041367", "target": "species_193708" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041367", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041367", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193720", "target": "reaction_10041367" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041335", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041335", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041335", "target": "species_193739" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041335", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193778", "target": "reaction_10041335" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193778", "target": "reaction_10041347" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038344", "target": "reaction_10041335" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038344", "target": "reaction_10041357" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038344", "target": "reaction_10038347" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038344", "target": "reaction_10041208" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038344", "target": "reaction_10041319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020170", "target": "species_10038344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041193", "target": "species_192060" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041193", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041193", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193384", "target": "reaction_10041193" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193384", "target": "reaction_10041177" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193384", "target": "reaction_10086026" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041190", "target": "reaction_10041193" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068208", "target": "species_10041190" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041353", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041353", "target": "species_213285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193760", "target": "reaction_10041353" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041355", "target": "species_193422" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193793", "target": "reaction_10041355" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041357", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041357", "target": "species_193741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041357", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041357", "target": "species_76577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041359", "target": "species_193785" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041359", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041359", "target": "species_113521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041217", "target": "species_192189" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041217", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041217", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041214", "target": "reaction_10041217" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004736", "target": "species_10041214" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041345", "target": "species_193757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041345", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041345", "target": "species_113521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041347", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041347", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041347", "target": "species_193739" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041347", "target": "species_76577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041349", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041349", "target": "species_193760" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041349" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041351" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041373" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041375" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041111" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041108", "target": "reaction_10041197" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002172", "target": "species_10041108" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041351", "target": "species_193707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041351", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193745", "target": "reaction_10041351" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047659", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047659", "target": "species_10047656" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047616", "target": "reaction_10047659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9H3", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9H3", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9H3", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9H3", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9H3", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003828", "target": "Q5E9H3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003828", "target": "species_10043848" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFR4", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030589", "target": "E1BFR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2P7", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019327", "target": "F1N2P7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIH8", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001558", "target": "F1MIH8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N173", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030185", "target": "F1N173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW1", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080859", "target": "F1MEW1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047656", "target": "reaction_10047763" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047763", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10047763", "target": "species_10047760" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047618", "target": "species_10047616" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047618", "target": "species_10047614" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047612", "target": "reaction_10047618" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047592", "target": "reaction_10047618" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047753", "target": "species_10047750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047753", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047714", "target": "reaction_10047753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02399", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02399", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02399", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02399", "target": "species_10081592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010212", "target": "Q02399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28199", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28199", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28199", "target": "species_10047695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q28199", "target": "species_10081592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056064", "target": "Q28199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E641", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E641", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E641", "target": "species_10047675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8E641", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085592", "target": "A8E641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER6", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER6", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER6", "target": "species_10047675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BER6", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005625", "target": "E1BER6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS7", "target": "species_10047714" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS7", "target": "species_10047750" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS7", "target": "species_10047675" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS7", "target": "species_10047732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023643", "target": "A2VDS7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047717", "target": "species_10047714" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047717", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047695", "target": "reaction_10047717" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047675", "target": "reaction_10047717" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047675", "target": "reaction_10047735" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047735", "target": "species_10047732" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047735", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047586", "target": "reaction_10047735" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043848", "target": "reaction_10047735" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045244", "target": "species_10045242" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045232", "target": "reaction_10045244" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045232", "target": "reaction_10045236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083792", "target": "species_10045232" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083792", "target": "A0A3Q1LQU8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045240", "target": "reaction_10045244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015162", "target": "species_10045240" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015162", "target": "E1BPB4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPB4", "target": "species_10045242" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQU8", "target": "species_10045242" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQU8", "target": "species_10045234" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045236", "target": "species_10045234" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045228", "target": "reaction_10045236" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089713", "target": "species_10089711" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089709", "target": "reaction_10089713" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2299699", "target": "reaction_10089713" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2299699", "target": "species_10089711" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2299699", "target": "reaction_10090179" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2299699", "target": "species_10090177" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090179", "target": "species_10090177" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043663", "target": "reaction_10090179" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043663", "target": "reaction_10043671" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061264", "target": "species_10043663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061264", "target": "F1N739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10090177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10043669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10045515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10049021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10089395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10048947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N739", "target": "species_10048949" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045517", "target": "species_10045515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043669", "target": "reaction_10045517" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043669", "target": "reaction_10089397" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045513", "target": "reaction_10045517" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080797", "target": "species_10045513" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080797", "target": "A0A3Q1LI98" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080797", "target": "species_10075170" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080797", "target": "species_10075167" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045515", "target": "reaction_10049024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI98", "target": "species_10045515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LI98", "target": "species_10049021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049024", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049024", "target": "species_10049021" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089397", "target": "species_10089395" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089393", "target": "reaction_10089397" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048935", "target": "species_10048933" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048931", "target": "reaction_10048935" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17421", "target": "species_10048931" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17421", "target": "species_10048933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043667", "target": "reaction_10048935" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043667", "target": "reaction_10043671" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043671", "target": "species_10043669" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048951", "target": "species_10048949" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048947", "target": "reaction_10048951" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N214", "target": "species_10048947" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N214", "target": "species_10048949" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021544", "target": "F1N214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047449", "target": "species_10047447" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047443", "target": "reaction_10047449" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047447", "target": "reaction_10047455" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047455", "target": "species_10047453" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047453", "target": "reaction_10047458" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047458", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047458", "target": "species_10039728" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045509", "target": "species_10045507" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045505", "target": "reaction_10045509" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082055", "target": "species_10045505" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082055", "target": "A0A3Q1MBH9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBH9", "target": "species_10045507" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10045224", "target": "species_10045222" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045216", "target": "reaction_10045224" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069192", "target": "species_10069190" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069057", "target": "reaction_10069192" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069057", "target": "reaction_10069418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH4", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086732", "target": "A0A3Q1LXH4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M5", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035350", "target": "F1N0M5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML02", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006988", "target": "F1ML02" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIE4", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037233", "target": "E1BIE4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII5", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020455", "target": "F1MII5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069190" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069186" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069127" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069273" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069118" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069428" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069432" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R6", "target": "species_10069139" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026780", "target": "F1N3R6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069161", "target": "reaction_10069192" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10069226", "target": "species_10049762" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069226", "target": "species_29370" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049739", "target": "reaction_10069226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021328", "target": "species_10049739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021328", "target": "species_10049762" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069218", "target": "reaction_10069226" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7Q3", "target": "species_10069218" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7Q3", "target": "species_10069208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7Q3", "target": "species_10069186" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073530", "target": "A0A3Q1M7Q3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073530", "target": "species_10069184" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069418", "target": "species_10069416" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069221", "target": "species_10069218" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069221", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069208", "target": "reaction_10069221" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069188", "target": "species_10069186" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069184", "target": "reaction_10069188" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069179", "target": "reaction_10069188" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069223", "target": "species_10069179" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045210", "target": "reaction_10069223" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069177", "target": "reaction_10069223" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069243", "target": "species_10069025" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068993", "target": "reaction_10069243" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069023", "target": "reaction_10069243" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069131", "target": "species_10069061" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069127", "target": "reaction_10069131" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069129", "target": "reaction_10069131" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069129", "target": "reaction_10069146" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069061", "target": "reaction_10069121" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069285", "target": "species_10069283" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069285", "target": "species_10069273" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069263", "target": "reaction_10069285" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069157", "target": "species_10069154" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069157", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069152", "target": "reaction_10069157" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069159", "target": "species_10069152" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069150", "target": "reaction_10069159" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048073", "target": "reaction_10069159" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069194", "target": "species_10069057" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069055", "target": "reaction_10069194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069037", "target": "reaction_10069194" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069146", "target": "species_10069127" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069121", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069121", "target": "species_10069118" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069144", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069144", "target": "species_10037315" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069141", "target": "reaction_10069144" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10069435", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069435", "target": "species_10069432" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10069428", "target": "reaction_10069435" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069148", "target": "species_10069141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069139", "target": "reaction_10069148" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069135", "target": "reaction_10069148" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091007", "target": "species_10091004" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090998", "target": "reaction_10091007" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079895", "target": "species_10090998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079895", "target": "A0A3Q1MTZ4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091004", "target": "reaction_10091009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTZ4", "target": "species_10091004" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091009", "target": "species_10091004" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074603", "target": "species_10074601" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074599", "target": "reaction_10074603" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025189", "target": "species_10074599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025189", "target": "A6QLD0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074595", "target": "reaction_10074603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF99", "target": "species_10074595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF99", "target": "species_10074601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF99", "target": "species_10074609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF99", "target": "species_10074639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF99", "target": "species_10074611" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081521", "target": "A0A3Q1NF99" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVZ5", "target": "species_10074595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVZ5", "target": "species_10074601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVZ5", "target": "species_10074609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVZ5", "target": "species_10074639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MVZ5", "target": "species_10074611" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071985", "target": "A0A3Q1MVZ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPN5", "target": "species_10074595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPN5", "target": "species_10074601" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077549", "target": "A0A3Q1MPN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLD0", "target": "species_10074601" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074641", "target": "species_10074639" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074609", "target": "reaction_10074641" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074609", "target": "reaction_10074613" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074637", "target": "reaction_10074641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006011", "target": "species_10074637" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006011", "target": "E1BFY8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFY8", "target": "species_10074639" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074613", "target": "species_10074611" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074607", "target": "reaction_10074613" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023124", "target": "species_10074607" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023124", "target": "F1MZT1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZT1", "target": "species_10074611" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081915", "target": "species_10081913" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081911", "target": "reaction_10081915" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZF2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074051", "target": "A0A3Q1LZF2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M139", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087011", "target": "A0A3Q1M139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MI98", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006440", "target": "F1MI98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148I8", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018185", "target": "Q148I8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPF8", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072411", "target": "A0A3Q1MPF8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP90", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013107", "target": "A6QP90" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV22", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076314", "target": "A0A3Q1LV22" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3T1", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026752", "target": "F1N3T1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWM2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023156", "target": "A7YWM2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5J4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043116", "target": "Q0P5J4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H712", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043126", "target": "A6H712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071728", "target": "A0A3Q1M4F4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6S1Q0", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001988", "target": "F6S1Q0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJB2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083663", "target": "A0A3Q1LJB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P08728", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006450", "target": "P08728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7W8", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047914", "target": "G3X7W8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027749", "target": "F1MFW9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX98", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064531", "target": "G3MX98" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QL7", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006445", "target": "Q17QL7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KMY1", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009403", "target": "A3KMY1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N362", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021519", "target": "F1N362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0W3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077014", "target": "A0A3Q1M0W3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI61", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008857", "target": "A0A452DI61" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B898", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018307", "target": "E1B898" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N566", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038457", "target": "F1N566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038458", "target": "Q148H4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP32", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038471", "target": "A6QP32" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148H8", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010391", "target": "Q148H8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWK3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010393", "target": "A7YWK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFP2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016832", "target": "A4IFP2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDN1", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067366", "target": "A0A3Q1MDN1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKE7", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057443", "target": "F1MKE7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNX5", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000815", "target": "A6QNX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZ71", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063931", "target": "G3MZ71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIJ6", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016839", "target": "A0A452DIJ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MYR8", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072474", "target": "A0A3Q1MYR8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046815", "target": "F1MUY2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081859" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081909" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081855" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10081919" }, { "type": "complex_component", "sub_type": "protein_component", "source": "M0QVY0", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000396", "target": "M0QVY0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081913", "target": "reaction_10081921" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081917", "target": "species_10081909" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081859", "target": "reaction_10081917" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081857", "target": "species_10081855" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081853", "target": "reaction_10081857" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081739", "target": "reaction_10081857" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081855", "target": "reaction_10081861" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081921", "target": "species_10081919" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081919", "target": "reaction_10082871" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081861", "target": "species_10081859" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082871", "target": "species_10082869" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082865", "target": "reaction_10082871" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYE1", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYE1", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064142", "target": "G3MYE1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX57", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX57", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065975", "target": "G3MX57" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q24JX9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q24JX9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064111", "target": "Q24JX9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B46", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B46", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049339", "target": "Q05B46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP0", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MWP0", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063461", "target": "G3MWP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2U6", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2U6", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064310", "target": "G3N2U6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B44", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B44", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024766", "target": "Q05B44" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8D5", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8D5", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000066373", "target": "A0A3Q1M8D5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9G9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9G9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000053063", "target": "E1B9G9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRY2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRY2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071483", "target": "A0A3Q1LRY2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0M4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0M4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069096", "target": "A0A3Q1N0M4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY72", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY72", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083666", "target": "A0A3Q1LY72" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083666", "target": "E1BAH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1L4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084386", "target": "A0A3Q1N1L4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084386", "target": "A0A3Q1M0F6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0F6", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0F6", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAH7", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAH7", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWC2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWC2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068881", "target": "A0A3Q1MWC2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V7", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3V7", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043153", "target": "F1N3V7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK19", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LK19", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087153", "target": "A0A3Q1LK19" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087153", "target": "A0A3Q1MEE6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087153", "target": "A0A3Q1LNZ0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087153", "target": "A0A3Q1LYD7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEE6", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MEE6", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNZ0", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNZ0", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP35", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP35", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043652", "target": "A6QP35" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUM3", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUM3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068312", "target": "A0A3Q1LUM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RZX2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6RZX2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043662", "target": "F6RZX2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYD7", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYD7", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUR9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUR9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071394", "target": "A0A3Q1LUR9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N073", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N073", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063306", "target": "G3N073" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPJ2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPJ2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084954", "target": "A0A3Q1LPJ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT3", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLT3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085549", "target": "A0A3Q1MLT3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWJ9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWJ9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043142", "target": "A7YWJ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIW5", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIW5", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034860", "target": "E1BIW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFR3", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFR3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075891", "target": "A0A3Q1MFR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF50", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF50", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082065", "target": "A0A3Q1NF50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN32", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN32", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084052", "target": "A0A3Q1MN32" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084052", "target": "A0A3Q1LFA4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084052", "target": "A0A3Q1N1W4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084052", "target": "A0A3Q1LQD4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084052", "target": "A0A3Q1N892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E345", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7E345", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043148", "target": "A7E345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFA4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFA4", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1W4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1W4", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMY6", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMY6", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043146", "target": "E1BMY6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQD4", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N892", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N892", "target": "species_10082869" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMY7", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMY7", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043145", "target": "E1BMY7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Z5", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Z5", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078641", "target": "A0A3Q1M5Z5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSL9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSL9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080742", "target": "A0A3Q1LSL9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NHC3", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NHC3", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072065", "target": "A0A3Q1NHC3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3D2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3D2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082261", "target": "A0A3Q1N3D2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC31", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC31", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065867", "target": "Q0VC31" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJJ0", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJJ0", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056985", "target": "A5PJJ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJJ4", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJJ4", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056308", "target": "A5PJJ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTA9", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTA9", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000021000", "target": "F1MTA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0A2", "target": "species_10082865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N0A2", "target": "species_10082869" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075298", "target": "A0A3Q1N0A2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050085", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050085", "target": "species_10050082" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050064", "target": "reaction_10050085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL3", "target": "species_10050064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL3", "target": "species_10050082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL3", "target": "species_10050080" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NNL3", "target": "species_10050114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079928", "target": "A0A3Q1NNL3" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10050074", "target": "reaction_10050085" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJZ7", "target": "species_10050074" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJZ7", "target": "species_10050082" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073649", "target": "A0A3Q1LJZ7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050116", "target": "species_10050114" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050080", "target": "reaction_10050116" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050112", "target": "reaction_10050116" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17667", "target": "species_10050112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P17667", "target": "species_10050114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038612", "target": "P17667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YS81", "target": "species_10050112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YS81", "target": "species_10050114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007923", "target": "Q7YS81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQN2", "target": "species_10050112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQN2", "target": "species_10050114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071565", "target": "A0A3Q1LQN2" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044090", "target": "species_10044088" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042680", "target": "reaction_10044090" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044088", "target": "reaction_10091023" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071769", "target": "species_10071591" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071589", "target": "reaction_10071769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082240", "target": "species_10071589" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082240", "target": "A0A3Q1M1S8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071585", "target": "reaction_10071769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022288", "target": "species_10071585" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022288", "target": "F1MPG0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071591", "target": "reaction_10071607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPG0", "target": "species_10071591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPG0", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPG0", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPG0", "target": "species_10071636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S8", "target": "species_10071591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S8", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S8", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S8", "target": "species_10071636" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071640", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071640", "target": "species_10071603" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071626", "target": "reaction_10071640" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071636" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHE4", "target": "species_10071615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003556", "target": "Q3MHE4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003556", "target": "species_10071595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071626" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071603" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071605" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Q4", "target": "species_10071636" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001867", "target": "E1B9Q4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001867", "target": "species_10071599" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071603", "target": "reaction_10071607" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071628", "target": "species_10071626" }, { "type": "reactant", "sub_type": "", "source": "species_5358514", "target": "reaction_10071628" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071624", "target": "reaction_10071628" }, { "type": "product", "sub_type": "", "source": "reaction_10071630", "target": "species_109966" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071630", "target": "species_164121" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071630", "target": "species_113541" }, { "type": "reactant", "sub_type": "", "source": "species_5358610", "target": "reaction_10071630" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_164121", "target": "reaction_10038938" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033501", "target": "reaction_10071630" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033501", "target": "reaction_10033504" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031920", "target": "species_10033501" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071767", "target": "species_10071624" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071599", "target": "reaction_10071767" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071595", "target": "reaction_10071767" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071595", "target": "reaction_10071765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071607", "target": "species_10071605" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071605", "target": "reaction_10071622" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071622", "target": "species_10071619" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071619", "target": "reaction_10071638" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071638", "target": "species_10071636" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071634", "target": "reaction_10071638" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012365", "target": "species_10071634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012365", "target": "E1BF15" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF15", "target": "species_10071636" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071617", "target": "species_10071615" }, { "type": "reactant", "sub_type": "", "source": "species_5358527", "target": "reaction_10071617" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071613", "target": "reaction_10071617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUI6", "target": "species_10071613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUI6", "target": "species_10071615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076740", "target": "A0A3Q1LUI6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076740", "target": "species_10071611" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071765", "target": "species_10071613" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071611", "target": "reaction_10071765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047196", "target": "species_10047194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047192", "target": "reaction_10047196" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y0", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y0", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y0", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4Y0", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082241", "target": "A0A3Q1M4Y0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQC6", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQC6", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQC6", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQC6", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076718", "target": "A0A3Q1LQC6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP89", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP89", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP89", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QP89", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043649", "target": "A6QP89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPA6", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPA6", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPA6", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPA6", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QPA6", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001120", "target": "A6QPA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G0", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G0", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G0", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G0", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2G0", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007359", "target": "F1N2G0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVZ9", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVZ9", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVZ9", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVZ9", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVZ9", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085880", "target": "A0A3Q1LVZ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNJ5", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNJ5", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNJ5", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNJ5", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNJ5", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054271", "target": "A0JNJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M165", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M165", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M165", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M165", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M165", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075504", "target": "A0A3Q1M165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM7", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM7", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM7", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM7", "target": "species_10047177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMM7", "target": "species_10047183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057007", "target": "Q1RMM7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62654", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62654", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62654", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O62654", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007041", "target": "O62654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6T8D8", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6T8D8", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6T8D8", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6T8D8", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015579", "target": "Q6T8D8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48616", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48616", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48616", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P48616", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "P48616" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10043014" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10044758" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10044760" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10043018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10043016" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10044743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024572", "target": "species_10044745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC60", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC60", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC60", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC60", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086078", "target": "A0A3Q1MC60" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KR48", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KR48", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KR48", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5KR48", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046179", "target": "Q5KR48" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68138", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68138", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68138", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68138", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006534", "target": "P68138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWR2", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWR2", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWR2", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWR2", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083316", "target": "A0A3Q1LWR2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIC1", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIC1", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIC1", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6QIC1", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014452", "target": "F6QIC1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYN5", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYN5", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYN5", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYN5", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063025", "target": "G3MYN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N264", "target": "species_10047192" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N264", "target": "species_10047194" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N264", "target": "species_10047181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N264", "target": "species_10047177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065361", "target": "G3N264" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047194", "target": "reaction_10047200" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047198", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047198", "target": "species_10047194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047181", "target": "reaction_10047198" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047200", "target": "species_10047177" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047177", "target": "reaction_10047186" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047186", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047186", "target": "species_10047181" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047183", "target": "reaction_10047186" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071824", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071821", "target": "reaction_10071824" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSF6", "target": "species_10071821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSF6", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067149", "target": "A0A3Q1LSF6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077468", "target": "species_10077466" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071836", "target": "reaction_10077468" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "species_10071836" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "P07501" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "species_10071828" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "species_10071830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "species_10071834" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008819", "target": "species_10071832" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077464", "target": "reaction_10077468" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN71", "target": "species_10077464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN71", "target": "species_10077466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008184", "target": "E1BN71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P07501", "target": "species_10077466" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071843", "target": "species_10071830" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071843", "target": "species_10071836" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071843", "target": "species_10071834" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071843", "target": "species_10071832" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071828", "target": "reaction_10071843" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071840", "target": "reaction_10071843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085692", "target": "species_10071840" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071819", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071816", "target": "reaction_10071819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY95", "target": "species_10071816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MY95", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044879", "target": "F1MY95" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q52PG9", "target": "species_10071816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q52PG9", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011882", "target": "Q52PG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVI5", "target": "species_10071816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MVI5", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045500", "target": "F1MVI5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LV43", "target": "species_10071816" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072593", "target": "A0A3Q1LV43" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5I5", "target": "species_10071816" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066696", "target": "A0A3Q1M5I5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053180", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053180", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053180", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053180", "target": "species_74113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053175", "target": "reaction_10053180" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10053175", "target": "reaction_10091759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0C6", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0C6", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018795", "target": "Q3T0C6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLL5", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLL5", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018181", "target": "A6QLL5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL6", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDL6", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049161", "target": "A2VDL6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8N5", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8N5", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013951", "target": "E1B8N5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJB8", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJB8", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077228", "target": "A0A3Q1MJB8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV7", "target": "species_10053175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWV7", "target": "species_10053178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073582", "target": "A0A3Q1LWV7" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10053178", "target": "reaction_10053180" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091759", "target": "species_10053178" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9684063", "target": "reaction_10091759" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048787", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048787", "target": "species_111875" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048770", "target": "reaction_10048787" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078158", "target": "species_10048770" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078158", "target": "species_10047897" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048785", "target": "reaction_10048787" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047893", "target": "species_74112" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047890", "target": "reaction_10047893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077323", "target": "species_10047890" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071876", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071873", "target": "reaction_10071876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH3", "target": "species_10071873" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004382", "target": "E1BEH3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT89", "target": "species_10071873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT89", "target": "species_10057653" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075452", "target": "A0A3Q1MT89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A0", "target": "species_10071873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A0", "target": "species_10057636" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005929", "target": "Q0P5A0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX91", "target": "species_10071873" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX91", "target": "species_10057636" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032182", "target": "F1MX91" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035579", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035579", "target": "species_10035566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035579", "target": "species_29364" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035564", "target": "reaction_10035579" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035564", "target": "reaction_10065597" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035564", "target": "reaction_10065673" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10123", "target": "species_10035564" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10123", "target": "species_10035566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10123", "target": "species_10065666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10123", "target": "species_10065681" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047900", "target": "P10123" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047900", "target": "species_10035562" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2473611", "target": "species_10035564" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035566", "target": "reaction_10088914" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035576", "target": "reaction_10035579" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065597", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065597", "target": "species_10035566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065597", "target": "species_73473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065594", "target": "reaction_10065597" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065644", "target": "species_10035564" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035562", "target": "reaction_10065644" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035562", "target": "reaction_10065683" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10035406", "target": "species_10035404" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035401", "target": "reaction_10035406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065646", "target": "species_2473604" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473615", "target": "reaction_10065646" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473604", "target": "reaction_10035558" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065601", "target": "reaction_10065646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065601", "target": "reaction_10065604" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065601", "target": "reaction_10065677" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065601", "target": "reaction_10065679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006585", "target": "species_10065601" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088914", "target": "species_8960974" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088914", "target": "species_10035562" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8960974", "target": "reaction_10065604" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065604", "target": "species_32737" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077751", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077751", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077751", "target": "species_6786225" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6786220", "target": "reaction_10077751" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077748", "target": "reaction_10077751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085962", "target": "species_10077748" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035558", "target": "species_10035556" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065606", "target": "species_29356" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065606", "target": "species_10035401" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_2565923", "target": "reaction_10065606" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049433", "target": "species_29426" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049430", "target": "reaction_10049433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065246", "target": "species_10049430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049464", "target": "species_29426" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049461", "target": "reaction_10049464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU3", "target": "species_10049461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034015", "target": "Q3SYU3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEU4", "target": "species_10049461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001238", "target": "E1BEU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWM2", "target": "species_10049461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075196", "target": "A0A3Q1LWM2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049440", "target": "species_29426" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049437", "target": "reaction_10049440" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007448", "target": "species_10049437" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049447", "target": "species_29426" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_442320", "target": "reaction_10049447" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049444", "target": "reaction_10049447" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010771", "target": "species_10049444" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071469", "target": "species_109496" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071466", "target": "reaction_10071469" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006554", "target": "species_10071466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070735", "target": "species_113542" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10070732", "target": "reaction_10070735" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017818", "target": "species_10070732" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071280", "target": "species_10071278" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071266", "target": "reaction_10071280" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037204", "target": "species_10071266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037204", "target": "A0A452DK44" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071276", "target": "reaction_10071280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCV8", "target": "species_10071276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCV8", "target": "species_10071278" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008743", "target": "F1MCV8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N598", "target": "species_10071276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N598", "target": "species_10071278" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079328", "target": "A0A3Q1N598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DK44", "target": "species_10071278" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071490", "target": "species_29926" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114632", "target": "reaction_10071490" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114632", "target": "reaction_10071476" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_114632", "target": "reaction_10071462" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071487", "target": "reaction_10071490" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087365", "target": "species_8941541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8941540", "target": "reaction_10087365" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209785", "target": "species_8941540" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209785", "target": "species_8941541" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209785", "target": "reaction_10049173" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087362", "target": "reaction_10087365" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFE5", "target": "species_10087362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027912", "target": "A4IFE5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E42", "target": "species_10087362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084512", "target": "Q08E42" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PRJ0", "target": "species_10087362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005636", "target": "F6PRJ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PK13", "target": "species_10087362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085971", "target": "A5PK13" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071476", "target": "species_29926" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10071473", "target": "reaction_10071476" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012110", "target": "species_10071473" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086343", "target": "species_8932842" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8932838", "target": "reaction_10086343" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086340", "target": "reaction_10086343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018143", "target": "species_10086340" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071462", "target": "species_29926" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071459", "target": "reaction_10071462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N136", "target": "species_10071459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002985", "target": "F1N136" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047930", "target": "species_113578" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30991", "target": "reaction_10047930" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_8851227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_8851461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_500101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_500120" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_500125" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_113578", "target": "reaction_10036907" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_113578", "target": "reaction_10036928" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113578", "target": "reaction_10051215" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_113578", "target": "species_500260" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047927", "target": "reaction_10047930" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N569", "target": "species_10047927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072103", "target": "A0A3Q1N569" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065369", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065369", "target": "species_2395817" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395852", "target": "reaction_10065369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395852", "target": "reaction_10065362" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065366", "target": "reaction_10065369" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065366", "target": "reaction_10065381" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025978", "target": "species_10065366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065371", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065371", "target": "species_2395878" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395868", "target": "reaction_10065371" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065356", "target": "reaction_10065371" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065356", "target": "reaction_10065359" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065356", "target": "reaction_10065362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLL8", "target": "species_10065356" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003218", "target": "F1MLL8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065386", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065386", "target": "species_2395964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395963", "target": "reaction_10065386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065375", "target": "reaction_10065386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065375", "target": "reaction_10065378" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065375", "target": "reaction_10065383" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004527", "target": "species_10065375" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065359", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065359", "target": "species_2395855" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395822", "target": "reaction_10065359" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065760", "target": "species_113550" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065760", "target": "species_2509805" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2509796", "target": "reaction_10065760" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509805", "target": "species_500120" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509805", "target": "species_500125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509805", "target": "species_500222" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065757", "target": "reaction_10065760" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065757", "target": "reaction_10065763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4Q9", "target": "species_10065757" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053197", "target": "A1A4Q9" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_2509819", "target": "reaction_10065760" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_2509819", "target": "reaction_10065763" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065328", "target": "species_2393950" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065328", "target": "species_159448" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2393945", "target": "reaction_10065328" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065325", "target": "reaction_10065328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBI8", "target": "species_10065325" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015090", "target": "A7MBI8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065763", "target": "species_113550" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065763", "target": "species_2509792" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2509811", "target": "reaction_10065763" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509811", "target": "species_8851092" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509811", "target": "species_8851462" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509792", "target": "species_8851461" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509792", "target": "species_500101" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509792", "target": "species_500120" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509792", "target": "species_500125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2509792", "target": "species_500260" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065362", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065362", "target": "species_2395817" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065378", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065378", "target": "species_2395877" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395880", "target": "reaction_10065378" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065381", "target": "species_2395817" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065381", "target": "species_29372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395883", "target": "reaction_10065381" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2395883", "target": "reaction_10065383" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065383", "target": "species_2395817" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065383", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065319", "target": "species_73578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065319", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1131972", "target": "reaction_10065319" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065316", "target": "reaction_10065319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMR8", "target": "species_10065316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068724", "target": "F1MMR8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072489", "target": "species_10072487" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072485", "target": "reaction_10072489" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007584", "target": "species_10072485" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007584", "target": "E1BP93" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072480", "target": "reaction_10072489" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009843", "target": "species_10072480" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009843", "target": "E1BIZ3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072487", "target": "reaction_10072497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIZ3", "target": "species_10072487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIZ3", "target": "species_10072495" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP93", "target": "species_10072487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BP93", "target": "species_10072495" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072497", "target": "species_10072495" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10033379", "target": "species_10033367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083861", "target": "species_10033367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083861", "target": "species_10033469" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083861", "target": "species_10033471" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033377", "target": "reaction_10033379" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG94", "target": "species_10033377" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005182", "target": "E1BG94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD75", "target": "species_10033377" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023554", "target": "E1BD75" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033412", "target": "species_10033410" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10033412", "target": "species_10033388" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033390", "target": "reaction_10033412" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ0", "target": "species_10033390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ0", "target": "species_10033410" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JZ0", "target": "species_10033510" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023040", "target": "Q56JZ0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023040", "target": "species_10033508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW5", "target": "species_10033390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIW5", "target": "species_10033510" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067336", "target": "A0A3Q1LIW5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067336", "target": "species_10033388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067336", "target": "species_10033414" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085788", "target": "species_10085786" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524163", "target": "reaction_10085788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02720", "target": "species_10085786" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086064", "target": "species_10086062" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086060", "target": "reaction_10086064" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071992", "target": "species_10086060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071992", "target": "A0A3Q1LZP9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZP9", "target": "species_10086062" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085808", "target": "species_10085794" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035781", "target": "reaction_10085808" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035781", "target": "reaction_10058877" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035781", "target": "reaction_10058812" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085792", "target": "reaction_10085808" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071421", "target": "species_10085792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071421", "target": "A0A3Q1MRL1" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085794", "target": "reaction_10085798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRL1", "target": "species_10085794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRL1", "target": "species_10085796" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085024", "target": "species_8865629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085024", "target": "species_83910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8865642", "target": "reaction_10085024" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085021", "target": "reaction_10085024" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017353", "target": "species_10085021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059141", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059141", "target": "species_1500596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500596", "target": "reaction_10059035" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500596", "target": "reaction_10058892" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500596", "target": "reaction_10059006" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500596", "target": "reaction_10058961" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500596", "target": "reaction_10083572" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059138", "target": "reaction_10059141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLQ9", "target": "species_10059138" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012081", "target": "E1BLQ9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059063", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059063", "target": "species_1524071" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059060", "target": "reaction_10059063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRY5", "target": "species_10059060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRY5", "target": "species_10059147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082323", "target": "A0A3Q1LRY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPV1", "target": "species_10059060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPV1", "target": "species_10059147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074052", "target": "A0A3Q1MPV1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085798", "target": "species_10085796" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10085798", "target": "species_10035781" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059094", "target": "species_264618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059094", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059079", "target": "reaction_10059094" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059079", "target": "reaction_10059082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCN8", "target": "species_10059079" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000037", "target": "E1BCN8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090489", "target": "species_9026761" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025001", "target": "reaction_10090489" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025001", "target": "reaction_10090480" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090486", "target": "reaction_10090489" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090486", "target": "reaction_10090491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKS0", "target": "species_10090486" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012836", "target": "Q2NKS0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090480", "target": "species_9026761" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039964", "target": "reaction_10090480" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUX5", "target": "species_10039964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUX5", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016866", "target": "F1MUX5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY34", "target": "species_10039964" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY34", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075425", "target": "A0A3Q1LY34" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090491", "target": "species_9026915" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024768", "target": "reaction_10090491" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044835", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044835", "target": "species_353575" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_353560", "target": "reaction_10044835" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_353560", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_353560", "target": "species_549250" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044832", "target": "reaction_10044835" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044832", "target": "reaction_10044837" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023087", "target": "species_10044832" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044837", "target": "species_353555" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044837", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076360", "target": "species_351628" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076360", "target": "species_351629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351627", "target": "reaction_10076360" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351627", "target": "reaction_10044828" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351627", "target": "reaction_10043986" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076357", "target": "reaction_10076360" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMK1", "target": "species_10076357" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021618", "target": "E1BMK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMS3", "target": "species_10076357" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021603", "target": "E1BMS3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043978", "target": "species_209785" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043978", "target": "species_83910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209818", "target": "reaction_10043978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209818", "target": "reaction_10044828" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209818", "target": "reaction_10043986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209818", "target": "reaction_10049083" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043975", "target": "reaction_10043978" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043975", "target": "reaction_10049083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021031", "target": "species_10043975" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044828", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044828", "target": "species_351630" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044828", "target": "species_351628" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351630", "target": "reaction_10043924" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043921", "target": "reaction_10044828" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043921", "target": "reaction_10043980" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043921", "target": "reaction_10043986" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043921", "target": "reaction_10043924" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043921", "target": "reaction_10043956" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071301", "target": "species_10043921" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043980", "target": "species_352331" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043980", "target": "species_352036" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352329", "target": "reaction_10043980" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_352329", "target": "reaction_10043956" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351639", "target": "reaction_10043980" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352331", "target": "species_879603" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352331", "target": "species_879628" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043986", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043986", "target": "species_352329" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043986", "target": "species_351628" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043924", "target": "species_622410" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043924", "target": "species_351639" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043956", "target": "species_352326" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043956", "target": "species_352036" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352326", "target": "species_879603" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352326", "target": "species_879628" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352326", "target": "species_10051868" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_352326", "target": "species_10051872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066745", "target": "species_10066743" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066741", "target": "reaction_10066745" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021980", "target": "species_10066741" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021980", "target": "Q3SYU1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYU1", "target": "species_10066743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066712", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066712", "target": "species_10066709" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066712", "target": "species_10066690" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066712", "target": "species_10066699" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066701", "target": "reaction_10066712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9B6", "target": "species_10066701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9B6", "target": "species_10066696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013805", "target": "E1B9B6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013805", "target": "species_10066699" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013805", "target": "species_10066694" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU9", "target": "species_10066701" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCU9", "target": "species_10066696" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015459", "target": "E1BCU9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015459", "target": "species_10066690" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066690", "target": "reaction_10081563" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081563", "target": "species_10066696" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066694", "target": "reaction_10081563" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066696", "target": "reaction_10066704" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081595", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081595", "target": "species_10081585" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081592", "target": "reaction_10081595" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080730", "target": "species_10080728" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10080726", "target": "reaction_10080730" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015051", "target": "species_10080726" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015051", "target": "E1BQ34" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ34", "target": "species_10080728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081629", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081629", "target": "species_10033519" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081626", "target": "reaction_10081629" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039179", "target": "species_10081626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066704", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066704", "target": "species_10066701" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080722", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10080722", "target": "species_10066659" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080722", "target": "species_10066666" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080722", "target": "species_10078728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066668", "target": "reaction_10080722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHM3", "target": "species_10066668" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHM3", "target": "species_10066666" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072457", "target": "A0A3Q1MHM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBC1", "target": "species_10066668" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084811", "target": "A0A3Q1MBC1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084811", "target": "species_10066659" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066659", "target": "reaction_10066670" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066666", "target": "reaction_10066670" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066870", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066870", "target": "species_10066862" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066867", "target": "reaction_10066870" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081622", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081622", "target": "species_10033519" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081619", "target": "reaction_10081622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078731", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078731", "target": "species_10078728" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078718", "target": "reaction_10078731" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009545", "target": "species_10078718" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009545", "target": "species_10078714" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066670", "target": "species_10066668" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078720", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10078720", "target": "species_10078718" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078714", "target": "reaction_10078720" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081602", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081602", "target": "species_10033524" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081599", "target": "reaction_10081602" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008055", "target": "species_10081599" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039801", "target": "species_10039799" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038468", "target": "reaction_10039801" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038468", "target": "reaction_10039852" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083057", "target": "species_10038468" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083057", "target": "A0A3Q1M5V7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039797", "target": "reaction_10039801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L05", "target": "species_10039797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L05", "target": "species_10039799" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074490", "target": "Q32L05" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5V7", "target": "species_10039799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5V7", "target": "species_10039850" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039852", "target": "species_10039850" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039803", "target": "reaction_10039852" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038033", "target": "species_10038031" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038023", "target": "reaction_10038033" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038023", "target": "reaction_10038035" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038027", "target": "reaction_10038033" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038027", "target": "reaction_10038035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065027", "target": "species_10038027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065027", "target": "G3MX31" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX31", "target": "species_10038031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX31", "target": "species_10038029" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038035", "target": "species_10038029" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038019", "target": "reaction_10038035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057027", "target": "species_10038019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057027", "target": "Q1JQB2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038015", "target": "reaction_10038035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009521", "target": "species_10038015" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009521", "target": "F1MWP1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWP1", "target": "species_10038029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQB2", "target": "species_10038029" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033833", "target": "species_34979" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30721", "target": "reaction_10033833" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_34979", "target": "reaction_10033840" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033830", "target": "reaction_10033833" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXH7", "target": "species_10033830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083727", "target": "A0A3Q1LXH7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033849", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033849", "target": "species_70919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30158", "target": "reaction_10033849" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033846", "target": "reaction_10033849" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBB6", "target": "species_10033846" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074746", "target": "A0A3Q1MBB6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054585", "target": "species_175992" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054585", "target": "species_113528" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054582", "target": "reaction_10054585" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA83", "target": "species_10054582" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013083", "target": "Q5EA83" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077758", "target": "species_6786250" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077758", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077758", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6786250", "target": "reaction_10086033" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077755", "target": "reaction_10077758" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023529", "target": "species_10077755" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086033", "target": "species_71285" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086033", "target": "species_8876775" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086030", "target": "reaction_10086033" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010790", "target": "species_10086030" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033840", "target": "species_30158" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033840", "target": "species_70106" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033837", "target": "reaction_10033840" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021647", "target": "species_10033837" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059066", "target": "species_1524072" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059066", "target": "species_1524067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524042", "target": "reaction_10059066" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524042", "target": "reaction_10058983" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524042", "target": "reaction_10058934" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524064", "target": "reaction_10059066" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058823", "target": "reaction_10059066" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058823", "target": "reaction_10058826" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058823", "target": "reaction_10058913" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000072", "target": "species_10058823" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092237", "target": "species_10055987" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092237", "target": "species_10092235" }, { "type": "reactant", "sub_type": "", "source": "species_9707575", "target": "reaction_10092237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092233", "target": "reaction_10092237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092233", "target": "reaction_10092293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB01", "target": "species_10092233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB01", "target": "species_10055991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB01", "target": "species_10055993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025702", "target": "E1BB01" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025702", "target": "species_10055987" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092235" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL3", "target": "species_10092279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005416", "target": "E1BJL3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005416", "target": "species_10092231" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005416", "target": "species_10092284" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005416", "target": "species_10092261" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055987", "target": "reaction_10092239" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092235", "target": "reaction_10092271" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092269", "target": "species_10092267" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092259", "target": "reaction_10092269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE98", "target": "species_10092259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE98", "target": "species_10092267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE98", "target": "species_10050304" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092239", "target": "species_10092233" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092231", "target": "reaction_10092239" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092231", "target": "reaction_10092273" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092271", "target": "species_10092259" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092225", "target": "species_10092223" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9707310", "target": "reaction_10092225" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9707310", "target": "reaction_10052914" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9707310", "target": "reaction_10064757" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_9707310" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10092223" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10092210" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10092212" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10081955" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10057046" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10057060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_71185", "target": "reaction_10040636" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10056405" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10089044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10089046" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10089054" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10089056" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10060204" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10052024" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10041891" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10052863" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10065129" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10065161" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10064755" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10064763" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_71185", "target": "species_10065171" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092221", "target": "reaction_10092225" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLL1", "target": "species_10092221" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLL1", "target": "species_10092223" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053034", "target": "E1BLL1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092227", "target": "species_917955" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092227", "target": "species_10064749" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064743", "target": "reaction_10092227" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064743", "target": "reaction_10092310" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064743", "target": "reaction_10064753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10064743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10064749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10092210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10092212" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10081949" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10081955" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10057046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10057060" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10065129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P01966", "target": "species_10065161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037545", "target": "P01966" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917955", "target": "species_10064743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917955", "target": "species_10081949" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917955", "target": "species_10064751" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_917955", "target": "species_10065171" }, { "type": "product", "sub_type": "", "source": "reaction_10052914", "target": "species_9707308" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092214", "target": "species_10064743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092214", "target": "species_9707624" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092214", "target": "species_9707647" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092210", "target": "reaction_10092214" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092210", "target": "reaction_10092308" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10092212", "target": "reaction_10092214" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081561", "target": "species_10066677" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066422", "target": "reaction_10081561" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091685", "target": "species_10091683" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091685", "target": "species_10040161" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091677", "target": "reaction_10091685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGU0", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGU0", "target": "species_10091683" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036227", "target": "F1MGU0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10038542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT3", "target": "species_10091219" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020830", "target": "Q0VCT3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10038542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMS4", "target": "species_10091219" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010016", "target": "F1MMS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10038542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A3KN17", "target": "species_10091219" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003522", "target": "A3KN17" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10091683" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10038542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGK3", "target": "species_10091219" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017541", "target": "E1BGK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10091677" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10091207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10091219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074715" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074711" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGN3", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033058", "target": "E1BGN3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033058", "target": "species_10040161" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035227", "target": "reaction_10091685" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038540", "target": "species_10038529" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038538", "target": "reaction_10038540" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15986", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15986", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15986", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15986", "target": "species_10038542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N079", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N079", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N079", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N079", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028108", "target": "F1N079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBF2", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBF2", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBF2", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBF2", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036177", "target": "Q3ZBF2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWH5", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWH5", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWH5", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWH5", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017339", "target": "A7YWH5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J8", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J8", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J8", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J8", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066873", "target": "A0A3Q1M1J8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGY5", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGY5", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGY5", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LGY5", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071579", "target": "A0A3Q1LGY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E950", "target": "species_10038538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E950", "target": "species_10038529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E950", "target": "species_10038531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E950", "target": "species_10038542" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008363", "target": "Q5E950" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038529", "target": "reaction_10038534" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038947", "target": "species_10038542" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30187", "target": "reaction_10038947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30187", "target": "reaction_10038534" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30187", "target": "species_8851233" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30187", "target": "species_482807" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038531", "target": "reaction_10038947" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038531", "target": "reaction_10038949" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30185", "target": "reaction_10038947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30185", "target": "reaction_10038534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30185", "target": "reaction_10036853" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30185", "target": "species_482807" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29892", "target": "reaction_10038947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29892", "target": "reaction_10038534" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29892", "target": "species_482807" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29604", "target": "reaction_10038947" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29604", "target": "reaction_10038534" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29604", "target": "reaction_10036879" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29604", "target": "species_482807" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038949", "target": "species_10038531" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038534", "target": "species_10038531" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087577", "target": "species_10062840" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062035", "target": "reaction_10087577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081723", "target": "species_10062035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081723", "target": "A0A3Q1M646" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10062840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10062335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10058697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10062205" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10063797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10058703" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M646", "target": "species_10064951" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087579", "target": "species_10062812" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062810", "target": "reaction_10087579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQC5", "target": "species_10062810" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQC5", "target": "species_10062812" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQC5", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQC5", "target": "species_10063797" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074238", "target": "A0A3Q1MQC5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087581", "target": "species_10060183" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060135", "target": "reaction_10087581" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060159", "target": "reaction_10087581" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060111", "target": "reaction_10087581" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060183", "target": "reaction_10060187" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087583", "target": "species_10062823" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062400", "target": "reaction_10087583" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044319", "target": "species_10062400" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044319", "target": "E1BKJ9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044319", "target": "species_10062033" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10062823" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10062832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10062852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10064335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKJ9", "target": "species_10063797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087569", "target": "species_10062790" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062025", "target": "reaction_10087569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065364", "target": "species_10062025" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065364", "target": "G3MXK9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK9", "target": "species_10062790" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK9", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXK9", "target": "species_10063797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087571", "target": "species_10062821" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062031", "target": "reaction_10087571" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017548", "target": "species_10062031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017548", "target": "F1MSJ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSJ7", "target": "species_10062821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSJ7", "target": "species_10062852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSJ7", "target": "species_10064335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSJ7", "target": "species_10063637" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087573", "target": "species_10062749" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062017", "target": "reaction_10087573" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062045", "target": "reaction_10087573" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062041", "target": "reaction_10087573" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062071", "target": "species_10062069" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062037", "target": "reaction_10062071" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067622", "target": "species_10062037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067622", "target": "A0A3Q1LYA4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYA4", "target": "species_10062069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYA4", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYA4", "target": "species_10063797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087563", "target": "species_10062801" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062027", "target": "reaction_10087563" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063888", "target": "species_10062027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063888", "target": "G3N021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N021", "target": "species_10062801" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N021", "target": "species_10063637" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N021", "target": "species_10063797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087565", "target": "species_10062781" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062023", "target": "reaction_10087565" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087567", "target": "species_10062763" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062019", "target": "reaction_10087567" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062043", "target": "reaction_10087567" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087585", "target": "species_10062832" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062033", "target": "reaction_10087585" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087587", "target": "species_10062772" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062021", "target": "reaction_10087587" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087589", "target": "species_10062709" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062015", "target": "reaction_10087589" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044446", "target": "species_10044444" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044438", "target": "reaction_10044446" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044438", "target": "reaction_10091184" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044438", "target": "reaction_10084895" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044434", "target": "reaction_10044446" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044410", "target": "reaction_10044446" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044410", "target": "reaction_10044726" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044424", "target": "reaction_10044446" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044726", "target": "species_10044724" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044722", "target": "reaction_10044726" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXW3", "target": "species_10044722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXW3", "target": "species_10044724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084577", "target": "A0A3Q1MXW3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044704", "target": "reaction_10044726" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092287", "target": "species_10092277" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092287", "target": "species_10092284" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092287", "target": "species_10086712" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10092281", "target": "reaction_10092287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD8", "target": "species_10092281" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUD8", "target": "species_10092279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069043", "target": "A0A3Q1LUD8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069043", "target": "species_10092277" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10092277", "target": "reaction_10092293" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092273", "target": "species_10092261" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_3785707", "target": "reaction_10092273" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_3785707", "target": "reaction_10091089" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092289", "target": "species_10092281" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10092279", "target": "reaction_10092289" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092293", "target": "species_10092279" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10092293", "target": "species_10055987" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057639", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057636", "target": "reaction_10057639" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9M4", "target": "species_10057636" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014309", "target": "E1B9M4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065673", "target": "species_10065666" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065673", "target": "species_76194" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16254", "target": "species_10065666" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065670", "target": "reaction_10065673" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065670", "target": "reaction_10077004" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065670", "target": "reaction_10083577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065670", "target": "reaction_10083575" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074877", "target": "species_10065670" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091560", "target": "species_29356" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091560", "target": "species_10065649" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048186", "target": "reaction_10091560" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048186", "target": "reaction_10065675" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065675", "target": "species_29356" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065675", "target": "species_10065649" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065677", "target": "species_2473611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473606", "target": "reaction_10065677" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065679", "target": "species_2473617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473607", "target": "reaction_10065679" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2473617", "target": "reaction_10065683" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065664", "target": "species_10065662" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065654", "target": "reaction_10065664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065662", "target": "reaction_10065687" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065683", "target": "species_10065681" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065687", "target": "species_10065685" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065687", "target": "species_975622" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091558", "target": "species_10065652" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091558", "target": "species_29356" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048190", "target": "reaction_10091558" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068899", "target": "species_10068893" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10068891", "target": "reaction_10068899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086463", "target": "species_10068891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086463", "target": "A0A3Q1NLC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLC4", "target": "species_10068893" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040355", "target": "species_10040353" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040351", "target": "reaction_10040355" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040351", "target": "reaction_10087385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10040351" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10040353" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10087383" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10087392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10087465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC36", "target": "species_10087491" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068675", "target": "E1BC36" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040345", "target": "reaction_10040355" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR9", "target": "species_10040345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYR9", "target": "species_10040353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083400", "target": "A0A3Q1LYR9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB9", "target": "species_10040345" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBB9", "target": "species_10040353" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014685", "target": "A7MBB9" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10040353", "target": "reaction_10087385" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088026", "target": "species_8954142" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088026", "target": "species_8952253" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2173763", "target": "reaction_10088026" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088023", "target": "reaction_10088026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009888", "target": "species_10088023" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058910", "target": "species_1498750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058910", "target": "species_1524021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524028", "target": "reaction_10058910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524028", "target": "reaction_10058829" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058868", "target": "reaction_10058910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058868", "target": "reaction_10058871" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058868", "target": "reaction_10058996" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058871", "target": "species_1498750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058871", "target": "species_1524021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975614", "target": "reaction_10058871" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_975614", "target": "reaction_10058809" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057007", "target": "species_113528" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1237009", "target": "reaction_10057007" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1237009", "target": "reaction_10058753" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049238", "target": "reaction_10057007" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049238", "target": "reaction_10049241" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049238", "target": "reaction_10049243" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P47865", "target": "species_10049238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P47865", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000993", "target": "P47865" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081968", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081968", "target": "species_10081955" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081968", "target": "species_29360" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10081949", "target": "reaction_10081968" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10081965", "target": "reaction_10081968" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIS5", "target": "species_10081965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068812", "target": "A0A3Q1LIS5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXD6", "target": "species_10081965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072609", "target": "A0A3Q1MXD6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058790", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058790", "target": "species_111627" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058787", "target": "reaction_10058790" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058787", "target": "reaction_10058792" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZA1", "target": "species_10058787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZA1", "target": "species_10058748" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045723", "target": "Q1LZA1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0H3", "target": "species_10058787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0H3", "target": "species_10058748" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023581", "target": "F1N0H3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057062", "target": "species_10057060" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057062", "target": "species_29368" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057046", "target": "reaction_10057062" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057060", "target": "reaction_10057070" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037739", "target": "species_10037737" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037735", "target": "reaction_10037739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071269", "target": "species_10037735" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071269", "target": "species_10037737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071269", "target": "A0A3Q1NFP6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058985", "target": "species_1524072" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058985", "target": "species_1524089" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524083", "target": "reaction_10058985" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498773", "target": "reaction_10058985" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498773", "target": "reaction_10058955" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058952", "target": "reaction_10058985" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058952", "target": "reaction_10058955" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079163", "target": "species_10058952" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058955", "target": "species_1524072" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058955", "target": "species_1524079" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524075", "target": "reaction_10058955" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058993", "target": "species_1524081" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058993", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524069", "target": "reaction_10058993" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035773", "target": "reaction_10058993" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035773", "target": "reaction_10058998" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058998", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058998", "target": "species_1524069" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524080", "target": "reaction_10058998" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045466", "target": "species_29804" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045463", "target": "reaction_10045466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q866T7", "target": "species_10045463" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028966", "target": "Q866T7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045455", "target": "species_29804" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045452", "target": "reaction_10045455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLU3", "target": "species_10045452" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015039", "target": "E1BLU3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045444", "target": "species_29804" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10045441", "target": "reaction_10045444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "D7R519", "target": "species_10045441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015932", "target": "D7R519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5X7", "target": "species_10045441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037612", "target": "G5E5X7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084238", "target": "species_10084236" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084224", "target": "reaction_10084238" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084224", "target": "reaction_10084228" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055485", "target": "species_10084224" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055485", "target": "F1MB46" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084234", "target": "reaction_10084238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3N1", "target": "species_10084234" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3N1", "target": "species_10084236" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063023", "target": "G3N3N1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB46", "target": "species_10084236" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB46", "target": "species_10084226" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084291", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084291", "target": "species_10084288" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084286", "target": "reaction_10084291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJA0", "target": "species_10084286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJA0", "target": "species_10084288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083670", "target": "E1BJA0" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10084272", "target": "reaction_10084291" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084272", "target": "reaction_10084276" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012236", "target": "species_10084272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012236", "target": "E1BHZ5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084261", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084261", "target": "species_10084254" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084252", "target": "reaction_10084261" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DE8", "target": "species_10084252" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DE8", "target": "species_10084254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016976", "target": "Q08DE8" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10084259", "target": "reaction_10084261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082752", "target": "species_10084259" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084228", "target": "species_10084226" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084220", "target": "reaction_10084228" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077895", "target": "species_10084220" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077895", "target": "A0A3Q1M443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M443", "target": "species_10084226" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084276", "target": "species_10084274" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084268", "target": "reaction_10084276" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHZ5", "target": "species_10084274" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084246", "target": "species_10084244" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084242", "target": "reaction_10084246" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061025", "target": "species_10084242" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061025", "target": "F1N746" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083720", "target": "reaction_10084246" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N746", "target": "species_10084244" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10044801", "target": "species_29356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10044801", "target": "species_351164" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044801", "target": "species_29514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044801", "target": "species_29610" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_351164", "target": "reaction_10044801" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351164", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_351164", "target": "species_549237" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_29610", "target": "reaction_10044801" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29610", "target": "reaction_10044844" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044798", "target": "reaction_10044801" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085149", "target": "species_10044798" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041177", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041177", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041177", "target": "species_192114" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192114", "target": "reaction_10041204" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041174", "target": "reaction_10041177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM29", "target": "species_10041174" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006957", "target": "E1BM29" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041500", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041500", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041500", "target": "species_194644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041500", "target": "species_29460" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194634", "target": "reaction_10041500" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194644", "target": "reaction_10041477" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041497", "target": "reaction_10041500" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002582", "target": "species_10041497" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041206", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041206", "target": "species_193846" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041206", "target": "species_113521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044232", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044232", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044232", "target": "species_211973" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044229", "target": "reaction_10044232" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035975", "target": "reaction_10044232" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035975", "target": "reaction_10035977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML85", "target": "species_10035975" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML85", "target": "species_10035969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010187", "target": "F1ML85" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28119", "target": "species_10035975" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28119", "target": "species_10035969" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYL2", "target": "species_10035975" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016391", "target": "F1MYL2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016391", "target": "species_10035973" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041195", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041195", "target": "species_192184" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041195", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192148", "target": "reaction_10041195" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041094", "target": "reaction_10041195" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041094", "target": "reaction_10041097" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NAD5", "target": "species_10041094" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070426", "target": "A0A3Q1NAD5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043964", "target": "species_8963879" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043964", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043964", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8963870", "target": "reaction_10043964" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8963870", "target": "species_10043883" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043961", "target": "reaction_10043964" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084891", "target": "species_10043961" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044225", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044225", "target": "species_215622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044225", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_215607", "target": "reaction_10044225" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043907", "target": "reaction_10044225" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043907", "target": "reaction_10043910" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003588", "target": "species_10043907" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043971", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043971", "target": "species_209800" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043971", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209804", "target": "reaction_10043971" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209804", "target": "species_10043895" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209804", "target": "species_10043901" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209804", "target": "species_10043982" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209804", "target": "species_10044728" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209804", "target": "species_10044732" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209800", "target": "reaction_10043910" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10043968", "target": "reaction_10043971" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022485", "target": "species_10043968" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044293", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044293", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044293", "target": "species_215584" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044280", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044280", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044280", "target": "species_213163" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_213162", "target": "reaction_10044280" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044277", "target": "reaction_10044280" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYW0", "target": "species_10044277" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063781", "target": "G3MYW0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044218", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044218", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044218", "target": "species_211944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211892", "target": "reaction_10044218" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044201", "target": "reaction_10044218" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044201", "target": "reaction_10044204" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044250", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044250", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044250", "target": "species_211952" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211993", "target": "reaction_10044250" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035908", "target": "reaction_10044250" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035908", "target": "reaction_10035911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJJ2", "target": "species_10035908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJJ2", "target": "species_10090495" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000869", "target": "Q2KJJ2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044477", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044477", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044477", "target": "species_156523" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_156522", "target": "reaction_10044477" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044474", "target": "reaction_10044477" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044223", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044223", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044223", "target": "species_213151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_213155", "target": "reaction_10044223" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044220", "target": "reaction_10044223" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035865", "target": "species_143501" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035865", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035865", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035865", "target": "species_76424" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_76424", "target": "species_174971" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035858", "target": "reaction_10035865" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035858", "target": "reaction_10035861" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035858", "target": "reaction_10035863" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035858", "target": "reaction_10071729" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035861", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035861", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035861", "target": "species_34889" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_47687", "target": "reaction_10035861" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_34889", "target": "species_174969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_34889", "target": "species_174971" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044275", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044275", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044275", "target": "species_211927" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211939", "target": "reaction_10044275" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044272", "target": "reaction_10044275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRH2", "target": "species_10044272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040300", "target": "F1MRH2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044182", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044182", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044182", "target": "species_213144" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044179", "target": "reaction_10044182" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035977", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035977", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035977", "target": "species_38987" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_38985", "target": "reaction_10035977" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_38987", "target": "species_176065" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035962", "target": "reaction_10035977" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044265", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044265", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044265", "target": "species_211937" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211855", "target": "reaction_10044265" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044262", "target": "reaction_10044265" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044204", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044204", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044204", "target": "species_211894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211906", "target": "reaction_10044204" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044270", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044270", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044270", "target": "species_211967" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_211977", "target": "reaction_10044270" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044267", "target": "reaction_10044270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU42", "target": "species_10044267" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079854", "target": "A0A3Q1MU42" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044167", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044167", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044167", "target": "species_76452" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044164", "target": "reaction_10044167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH2", "target": "species_10044164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH2", "target": "species_10035875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYH2", "target": "species_10038057" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065779", "target": "G3MYH2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065779", "target": "species_10035869" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035911", "target": "species_143501" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035911", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035911", "target": "species_113564" }, { "type": "product", "sub_type": "other", "source": "reaction_10035911", "target": "species_76455" }, { "type": "reactant", "sub_type": "other", "source": "species_39703", "target": "reaction_10035911" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035878", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035878", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035878", "target": "species_76452" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035875", "target": "reaction_10035878" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059035", "target": "species_1500581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059035", "target": "species_109395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500603", "target": "reaction_10059035" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059032", "target": "reaction_10059035" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QM4", "target": "species_10059032" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010310", "target": "Q17QM4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059082", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059082", "target": "species_1498751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059130", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059130", "target": "species_1500603" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059127", "target": "reaction_10059130" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLB5", "target": "species_10059127" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070509", "target": "A0A3Q1MLB5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059150", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059150", "target": "species_428686" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059147", "target": "reaction_10059150" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRD9", "target": "species_10059147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024637", "target": "F1MRD9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076994", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076994", "target": "species_113532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076994", "target": "species_5693978" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696414", "target": "reaction_10076994" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113532", "target": "reaction_10034215" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076991", "target": "reaction_10076994" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9S4", "target": "species_10076991" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013587", "target": "Q5E9S4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077004", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077004", "target": "species_1500596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696449", "target": "reaction_10077004" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6782195", "target": "reaction_10077004" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058892", "target": "species_76116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058892", "target": "species_1500594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498728", "target": "reaction_10058892" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498728", "target": "reaction_10058894" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498728", "target": "reaction_10058819" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1500594", "target": "reaction_10058948" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058889", "target": "reaction_10058892" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058889", "target": "reaction_10058894" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058889", "target": "reaction_10058961" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058889", "target": "reaction_10058948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004368", "target": "species_10058889" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059006", "target": "species_1500594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059006", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058894", "target": "species_76116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058894", "target": "species_1500596" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058961", "target": "species_1498728" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058961", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058819", "target": "species_1500593" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058819", "target": "species_76116" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058816", "target": "reaction_10058819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUK0", "target": "species_10058816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058948", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058948", "target": "species_1500596" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083572", "target": "species_1500594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083572", "target": "species_76194" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083569", "target": "reaction_10083572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010259", "target": "species_10083569" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038938", "target": "species_10038936" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038932", "target": "reaction_10038938" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083614", "target": "species_10083612" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083610", "target": "reaction_10083614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U4", "target": "species_10083610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T0U4", "target": "species_10083612" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040283", "target": "Q3T0U4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KM7", "target": "species_10083610" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KM7", "target": "species_10083612" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011923", "target": "Q32KM7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083594", "target": "reaction_10083614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M564", "target": "species_10083594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M564", "target": "species_10083612" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077795", "target": "A0A3Q1M564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060553", "target": "species_1806212" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060553", "target": "species_29372" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806289", "target": "reaction_10060553" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060465", "target": "reaction_10060553" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060465", "target": "reaction_10060468" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060465", "target": "reaction_10060558" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060465", "target": "reaction_10060574" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078957", "target": "species_10060465" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060537", "target": "species_1806198" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060537", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806195", "target": "reaction_10060537" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806198", "target": "reaction_10060468" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060489", "target": "reaction_10060537" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060489", "target": "reaction_10060501" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060489", "target": "reaction_10060614" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060489", "target": "reaction_10060516" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE68", "target": "species_10060489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE68", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE68", "target": "species_10060495" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046627", "target": "E1BE68" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060468", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060468", "target": "species_1806195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088526", "target": "species_8952909" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088526", "target": "species_8952905" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8952909", "target": "reaction_10088526" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088523", "target": "reaction_10088526" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028950", "target": "species_10088523" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037674", "target": "species_10037672" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037670", "target": "reaction_10037674" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037670", "target": "reaction_10072614" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10037670" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10037672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10072612" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10091019" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10091021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10091025" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2Q2", "target": "species_10091027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAP00000064310", "target": "A0A3Q1M2Q2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037644", "target": "reaction_10037674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT9", "target": "species_10037672" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT9", "target": "species_10037628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT9", "target": "species_10051167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUT9", "target": "species_10051173" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037678", "target": "species_10037626" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037626", "target": "reaction_10037630" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037630", "target": "species_10037269" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037630", "target": "species_10037628" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037275", "target": "reaction_10037630" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R2C4", "target": "species_10037275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R2C4", "target": "species_10037628" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R2C4", "target": "species_10051179" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025701", "target": "F6R2C4" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025701", "target": "species_10037273" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047900", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047900", "target": "species_139827" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_427899", "target": "reaction_10047900" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047897", "target": "reaction_10047900" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076824", "target": "species_5696026" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076824", "target": "species_5696037" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5696066", "target": "reaction_10076824" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_6814795", "target": "species_5696066" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696069", "target": "reaction_10076824" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076821", "target": "reaction_10076824" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFM9", "target": "species_10076821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074114", "target": "A0A3Q1MFM9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085340", "target": "species_426755" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085340", "target": "species_426658" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085337", "target": "reaction_10085340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9I9", "target": "species_10085337" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013851", "target": "E1B9I9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUM3", "target": "species_10085337" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079883", "target": "A0A3Q1MUM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N293", "target": "species_10085337" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069345", "target": "A0A3Q1N293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059091", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059091", "target": "species_426955" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426955", "target": "reaction_10059044" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059088", "target": "reaction_10059091" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZU2", "target": "species_10059088" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065725", "target": "G3MZU2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059044", "target": "species_426639" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059044", "target": "species_109395" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_426910", "target": "reaction_10059044" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426910", "target": "species_429652" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_426910", "target": "species_429648" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059041", "target": "reaction_10059044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T103", "target": "species_10059041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010454", "target": "Q3T103" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071344", "target": "species_10071342" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071340", "target": "reaction_10071344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY1", "target": "species_10071340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY1", "target": "species_10071342" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002436", "target": "Q2KHY1" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171142", "target": "reaction_10071344" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_171142", "target": "species_10071342" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_171142", "target": "species_8866926" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_171142", "target": "species_10084422" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_171142", "target": "species_10084692" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059849", "target": "species_1602419" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059849", "target": "species_1602366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_33625", "target": "reaction_10059849" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058943", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058943", "target": "species_1498724" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498724", "target": "reaction_10058880" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085310", "target": "species_33625" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085310", "target": "species_1806234" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085307", "target": "reaction_10085310" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI45", "target": "species_10085307" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070851", "target": "A0A3Q1MI45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFD9", "target": "species_10085307" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012114", "target": "F1MFD9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWY5", "target": "species_10085307" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073265", "target": "A0A3Q1LWY5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058945", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058945", "target": "species_1498724" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058880", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058880", "target": "species_1500646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058800", "target": "reaction_10058880" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10058800", "target": "reaction_10058916" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058916", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058916", "target": "species_1500646" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498722", "target": "reaction_10058916" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059014", "target": "species_1498722" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059014", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059011", "target": "reaction_10059014" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059011", "target": "reaction_10059021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059016", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059016", "target": "species_1498740" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1483256", "target": "reaction_10059016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1483256", "target": "reaction_10059018" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1483256", "target": "reaction_10059021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498740", "target": "reaction_10058812" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059018", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059018", "target": "species_1498740" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058826", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058826", "target": "species_1524042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524047", "target": "reaction_10058826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524038", "target": "reaction_10058826" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524038", "target": "reaction_10058913" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059021", "target": "species_1498730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059021", "target": "species_1524021" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1498730", "target": "reaction_10058877" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058877", "target": "species_1483256" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058877", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058812", "target": "species_1483256" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058812", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058913", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058913", "target": "species_1524042" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524027", "target": "reaction_10058913" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058983", "target": "species_1524047" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058983", "target": "species_1524085" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058931", "target": "reaction_10058983" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058931", "target": "reaction_10058934" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059847", "target": "species_1602415" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059847", "target": "species_1602366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058934", "target": "species_1524027" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058934", "target": "species_1524085" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058809", "target": "species_426925" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058809", "target": "species_76194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058806", "target": "reaction_10058809" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058806", "target": "reaction_10058829" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPE0", "target": "species_10058806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079571", "target": "A0A3Q1MPE0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058970", "target": "species_1524028" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058970", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058829", "target": "species_426925" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058829", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058990", "target": "species_1524028" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058990", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058987", "target": "reaction_10058990" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059856", "target": "species_1602390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059856", "target": "species_1602366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059858", "target": "species_1602390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059858", "target": "species_1602366" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085826", "target": "species_8874450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085826", "target": "species_5696116" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8874447", "target": "reaction_10085826" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17810", "target": "species_8874447" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17476", "target": "species_8874447" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36313", "target": "species_8874450" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36314", "target": "species_8874450" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085823", "target": "reaction_10085826" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076823", "target": "species_10085823" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058996", "target": "species_1524021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058996", "target": "species_975614" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059121", "target": "species_264618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059121", "target": "species_1500646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059118", "target": "reaction_10059121" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018461", "target": "species_10059118" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059073", "target": "species_1498751" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059073", "target": "species_1500646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059070", "target": "reaction_10059073" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077015", "target": "species_10059070" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059101", "target": "species_159450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059101", "target": "species_1524064" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_110577", "target": "reaction_10059101" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10059098", "target": "reaction_10059101" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007970", "target": "species_10059098" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057390", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057387", "target": "reaction_10057390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM97", "target": "species_10057387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BM97", "target": "species_10057385" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061021", "target": "E1BM97" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL87", "target": "species_10057387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL87", "target": "species_10057385" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022679", "target": "E1BL87" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIS4", "target": "species_10057387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIS4", "target": "species_10057385" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023219", "target": "E1BIS4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057607", "target": "species_10057387" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057385", "target": "reaction_10057607" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049326", "target": "species_76190" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049326", "target": "species_83910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_433138", "target": "reaction_10049326" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049323", "target": "reaction_10049326" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006144", "target": "species_10049323" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049333", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049333", "target": "species_174375" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049330", "target": "reaction_10049333" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078998", "target": "species_10049330" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051305", "target": "species_561078" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051305", "target": "species_561075" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_561049", "target": "reaction_10051305" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:104011", "target": "species_561049" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:104011", "target": "species_561078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_561052", "target": "species_561049" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_561052", "target": "species_561078" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051302", "target": "reaction_10051305" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIJ1", "target": "species_10051302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018132", "target": "F1MIJ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1R8", "target": "species_10051302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064695", "target": "G3N1R8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MII8", "target": "species_10051302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018139", "target": "F1MII8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051314", "target": "species_373863" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051314", "target": "species_30034" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429056", "target": "reaction_10051314" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30034", "target": "species_429078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_30034", "target": "species_429148" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30034", "target": "reaction_10066277" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051311", "target": "reaction_10051314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068956", "target": "species_10051311" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051307", "target": "species_549237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_549266", "target": "reaction_10051307" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46020", "target": "species_446597" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6801", "target": "species_446597" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16737", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16737", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16737", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16737", "target": "species_446597" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65133", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65133", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65133", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:65133", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_549237" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:641", "target": "species_446597" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31941", "target": "species_549266" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:31941", "target": "species_549237" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_549237", "target": "reaction_10051283" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10051281", "target": "reaction_10051307" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10051281", "target": "reaction_10051283" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10051281", "target": "reaction_10086350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055483", "target": "species_10051281" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051325", "target": "species_351626" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051325", "target": "species_597623" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_597604", "target": "reaction_10051325" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051322", "target": "reaction_10051325" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016935", "target": "species_10051322" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051276", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051276", "target": "species_549260" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_549261", "target": "reaction_10051276" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051273", "target": "reaction_10051276" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013203", "target": "species_10051273" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051283", "target": "species_549266" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051269", "target": "species_549250" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_549264", "target": "reaction_10051269" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42820", "target": "species_549264" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42820", "target": "species_549250" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42820", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:42820", "target": "species_446597" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_549250", "target": "reaction_10051286" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051286", "target": "species_549264" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067993", "target": "species_10067991" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048710", "target": "reaction_10067993" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067989", "target": "reaction_10067993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007194", "target": "species_10067989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007194", "target": "E1B9H3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007194", "target": "species_10067995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9H3", "target": "species_10067991" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071241", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071241", "target": "species_10071232" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071123", "target": "reaction_10071241" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071123", "target": "reaction_10071127" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071232", "target": "reaction_10071313" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071238", "target": "reaction_10071241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMH9", "target": "species_10071238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMH9", "target": "species_10071205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004925", "target": "Q1RMH9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7H0", "target": "species_10071238" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7H0", "target": "species_10071205" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003437", "target": "F1N7H0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068008", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10068008", "target": "species_10067989" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067995", "target": "reaction_10068008" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068005", "target": "reaction_10068008" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10068005" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10076295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10075051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEI6", "target": "species_10074665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8V1", "target": "species_10068005" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066572", "target": "A0A3Q1M8V1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071208", "target": "species_113550" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10071208", "target": "species_10071169" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071208", "target": "species_10071195" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071171", "target": "reaction_10071208" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JY0", "target": "species_10071171" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q56JY0", "target": "species_10071125" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026632", "target": "Q56JY0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026632", "target": "species_10071169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026632", "target": "species_10071069" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071205", "target": "reaction_10071208" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071313", "target": "species_10071123" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071313", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071304", "target": "reaction_10071313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIM3", "target": "species_10071304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006600", "target": "Q0IIM3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148J7", "target": "species_10071304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023720", "target": "Q148J7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBG5", "target": "species_10071304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007039", "target": "Q3ZBG5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MIU2", "target": "species_10071304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018131", "target": "F1MIU2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MSS9", "target": "species_10071304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017468", "target": "F1MSS9" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10071311", "target": "reaction_10071313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQM3", "target": "species_10071311" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074682", "target": "A0A3Q1MQM3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071127", "target": "species_10071125" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10071069", "target": "reaction_10071127" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092312", "target": "species_10038645" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9709326", "target": "reaction_10092312" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040636", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040636", "target": "species_189385" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040636", "target": "species_71067" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040636", "target": "species_189396" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040636", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040633", "target": "reaction_10040636" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10047807", "target": "species_10047797" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047807", "target": "species_10047805" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047807", "target": "species_10047771" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047799", "target": "reaction_10047807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80425", "target": "species_10047799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80425", "target": "species_10091609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80425", "target": "species_10091607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80425", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P80425", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024032", "target": "P80425" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024032", "target": "species_10047797" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047793", "target": "reaction_10047807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II51", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0II51", "target": "species_10047805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078286", "target": "Q0II51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1K9", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1K9", "target": "species_10047805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007749", "target": "F1N1K9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007749", "target": "species_10041047" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159151", "target": "species_10047793" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159151", "target": "species_10047805" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159151", "target": "reaction_10038338" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159151", "target": "species_10091609" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047777", "target": "reaction_10047807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10047771" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086477" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086490" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086536" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086538" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTR3", "target": "species_10086499" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013167", "target": "F1MTR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA13", "target": "species_10047777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA13", "target": "species_10047805" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA13", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA13", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068423", "target": "Q5EA13" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092308", "target": "species_10092212" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092310", "target": "species_109276" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10092310", "target": "species_10092210" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10092310", "target": "species_352327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067416", "target": "species_10067413" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067416", "target": "species_10067395" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067409", "target": "reaction_10067416" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE86", "target": "species_10067409" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE86", "target": "species_10067413" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE86", "target": "species_10068573" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE86", "target": "species_10068571" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005683", "target": "E1BE86" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10067409" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10067413" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10068573" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10068571" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3299744", "target": "reaction_10073481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10073479" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3299744", "target": "species_10073462" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067395", "target": "reaction_10067398" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209799", "target": "species_10067395" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209799", "target": "species_10067385" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209799", "target": "species_10069852" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_209799", "target": "species_10068713" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209799", "target": "reaction_10073464" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056408", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056408", "target": "species_1222424" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056408", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1222424", "target": "reaction_10067398" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056405", "target": "reaction_10056408" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076891", "target": "species_5696194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076891", "target": "species_113573" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696199", "target": "reaction_10076891" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076888", "target": "reaction_10076891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045076", "target": "species_10076888" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087866", "target": "species_10067409" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068573", "target": "reaction_10087866" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067388", "target": "species_351629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067388", "target": "species_352327" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067385", "target": "reaction_10067388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R4N7", "target": "species_10067385" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R4N7", "target": "species_10069852" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018580", "target": "F6R4N7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068575", "target": "species_10068573" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067407", "target": "reaction_10068575" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068571", "target": "reaction_10068575" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069854", "target": "species_10067385" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069852", "target": "reaction_10069854" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067731", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067731", "target": "species_1655887" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1655882", "target": "reaction_10067731" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067728", "target": "reaction_10067731" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ1", "target": "species_10067728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKZ1", "target": "species_10034163" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009363", "target": "E1BKZ1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080786", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10080786", "target": "species_3341331" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1247892", "target": "reaction_10080786" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1247892", "target": "reaction_10087515" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10080783", "target": "reaction_10080786" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7E3", "target": "species_10080783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068263", "target": "A0A3Q1M7E3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCF5", "target": "species_10080783" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015939", "target": "F1MCF5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067735", "target": "species_10038546" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067735", "target": "species_189461" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3341308", "target": "reaction_10067735" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3341308", "target": "reaction_10068716" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189461", "target": "reaction_10040654" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189461", "target": "reaction_10040663" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034166", "target": "species_29450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034166", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034163", "target": "reaction_10034166" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10067722", "target": "species_10067705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067722", "target": "species_113521" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067702", "target": "reaction_10067722" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067702", "target": "reaction_10068578" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10067702", "target": "reaction_10090679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000014", "target": "species_10067702" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000014", "target": "species_10067705" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000014", "target": "Q95108" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614617", "target": "reaction_10067722" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067719", "target": "reaction_10067722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P35705", "target": "species_10067719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011505", "target": "P35705" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9BGI1", "target": "species_10067719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011403", "target": "Q9BGI1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011403", "target": "species_10067717" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068716", "target": "species_189481" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068716", "target": "species_189461" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10068713", "target": "reaction_10068716" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067375", "target": "species_113533" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067375", "target": "species_1614617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3299683", "target": "reaction_10067375" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067372", "target": "reaction_10067375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHL1", "target": "species_10067372" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHL1", "target": "species_10075337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHL1", "target": "species_10075341" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008569", "target": "E1BHL1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067744", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067744", "target": "species_111745" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067741", "target": "reaction_10067744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068578", "target": "species_3697842" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10068578", "target": "species_10067705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10068578", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3697881", "target": "reaction_10068578" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10067717", "target": "reaction_10068578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067398", "target": "species_29368" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067398", "target": "species_29408" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066873", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066873", "target": "species_10066867" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066855", "target": "reaction_10066873" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066779", "target": "species_10066770" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066779", "target": "species_159939" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066768", "target": "reaction_10066779" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066768", "target": "reaction_10066832" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066770", "target": "reaction_10066876" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066776", "target": "reaction_10066779" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066876", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066876", "target": "species_10066768" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044327", "target": "reaction_10066876" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066832", "target": "species_10066830" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066828", "target": "reaction_10066832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10066826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10089560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLQ0", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000025", "target": "A6QLQ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10066826" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10088592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10088594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10089560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR89", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086711", "target": "A0A3Q1LR89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFG7", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFG7", "target": "species_10066830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006041", "target": "E1BFG7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBA7", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBA7", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBA7", "target": "species_10088592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MBA7", "target": "species_10088594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073548", "target": "A0A3Q1MBA7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KX7", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KX7", "target": "species_10066830" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KX7", "target": "species_10088592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32KX7", "target": "species_10088594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073960", "target": "Q32KX7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU2", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKU2", "target": "species_10066830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061326", "target": "F1MKU2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDR6", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MDR6", "target": "species_10066830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076497", "target": "A0A3Q1MDR6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCA3", "target": "species_10066828" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCA3", "target": "species_10066830" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074913", "target": "A0A3Q1MCA3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066857", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066857", "target": "species_10066855" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066853", "target": "reaction_10066857" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066786", "target": "species_10050214" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066786", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066783", "target": "reaction_10066786" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011949", "target": "species_10066783" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088964", "target": "species_10066776" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066774", "target": "reaction_10088964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111793", "target": "reaction_10088964" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111793", "target": "reaction_10084497" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076298", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076298", "target": "species_10076295" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076298", "target": "species_10074441" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074450", "target": "reaction_10076298" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10076295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10075051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MIR9", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083355", "target": "A0A3Q1MIR9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10076295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10035718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10068852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10075051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10035710" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6W2", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014945", "target": "G3X6W2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014945", "target": "species_10035704" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074450" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10076295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074427" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10035718" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074438" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074443" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074448" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10068852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10075051" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074733" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074745" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074530" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10076300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6PSE2", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017598", "target": "F6PSE2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017598", "target": "species_10074753" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017598", "target": "species_10035716" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076295", "target": "reaction_10076332" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074429", "target": "species_10074427" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074417", "target": "reaction_10074429" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074425", "target": "reaction_10074429" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074425", "target": "reaction_10076343" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074427", "target": "reaction_10078369" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074431", "target": "species_10074417" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035718", "target": "reaction_10074431" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035718", "target": "reaction_10068854" }, { "type": "reactant", "sub_type": "", "source": "species_3785706", "target": "reaction_10074431" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074446", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074446", "target": "species_10074443" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074446", "target": "species_10074441" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074438", "target": "reaction_10074446" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078369", "target": "species_10074438" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078369", "target": "species_2485002" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074453", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074453", "target": "species_10074450" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074448", "target": "reaction_10074453" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069684", "target": "species_10069682" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069680", "target": "reaction_10069684" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069676", "target": "reaction_10069684" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027216", "target": "species_10069676" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027216", "target": "F1MLB1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLB1", "target": "species_10069682" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076343", "target": "species_10074448" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068852", "target": "reaction_10076343" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10068852", "target": "reaction_10075306" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068854", "target": "species_10068852" }, { "type": "reactant", "sub_type": "", "source": "species_75165", "target": "reaction_10068854" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10066630", "target": "species_10066628" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066626", "target": "reaction_10066630" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000437", "target": "species_10066626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000437", "target": "species_10066628" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091401", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091401", "target": "species_10091333" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091329", "target": "reaction_10091401" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091329", "target": "reaction_10091336" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091333", "target": "reaction_10091356" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091399", "target": "reaction_10091401" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3B7L5", "target": "species_10091399" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010532", "target": "Q3B7L5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS15", "target": "species_10091399" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083520", "target": "A0A3Q1MS15" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NF19", "target": "species_10091399" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067422", "target": "A0A3Q1NF19" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091336", "target": "species_29438" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091336", "target": "species_10091333" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091354", "target": "species_10091342" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091354", "target": "species_10091338" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091344", "target": "reaction_10091354" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091338", "target": "reaction_10091356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091356", "target": "species_10091340" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091340", "target": "reaction_10091351" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091404", "target": "species_10091360" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091358", "target": "reaction_10091404" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091360", "target": "reaction_10091365" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091365", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091365", "target": "species_10091362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091351", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091351", "target": "species_10091344" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10091349", "target": "reaction_10091351" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087052", "target": "species_10091349" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073481", "target": "species_10073479" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073456", "target": "reaction_10073481" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073456", "target": "reaction_10073460" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Y6", "target": "species_10073456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Y6", "target": "species_10073479" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6Y6", "target": "species_10073458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069619", "target": "A0A3Q1M6Y6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68301", "target": "species_10073456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68301", "target": "species_10073479" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P68301", "target": "species_10073458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034373", "target": "P68301" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073464", "target": "species_10073462" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073464", "target": "species_29426" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10073444", "target": "reaction_10073464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P37359", "target": "species_10073444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P37359", "target": "species_10073462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P37359", "target": "species_10073466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022460", "target": "P37359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022460", "target": "species_10073442" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073468", "target": "species_10073466" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073442", "target": "reaction_10073468" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073442", "target": "reaction_10073446" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1132098", "target": "reaction_10073468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1132098", "target": "species_10073466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1132098", "target": "reaction_10073460" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1132098", "target": "species_10073458" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073460", "target": "species_10073458" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073446", "target": "species_10073444" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075304", "target": "species_10075301" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075304", "target": "species_30555" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075297", "target": "reaction_10075304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075297" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075301" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075316" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10074778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075030" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10074795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10074789" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10076336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLY2", "target": "species_10075051" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085498", "target": "A0A3Q1NLY2" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30555", "target": "reaction_10036886" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075323", "target": "species_10075321" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036900", "target": "reaction_10075323" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2F9", "target": "species_10036900" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2F9", "target": "species_10075321" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081405", "target": "F1N2F9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF81", "target": "species_10036900" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF81", "target": "species_10075321" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075817", "target": "A0A3Q1LF81" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075316", "target": "reaction_10075323" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075321", "target": "reaction_10075326" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075306", "target": "species_10075297" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074778", "target": "reaction_10075306" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075326", "target": "species_10035718" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075326", "target": "species_10036900" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075326", "target": "species_10074778" }, { "type": "product", "sub_type": "", "source": "reaction_10075326", "target": "species_5687670" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075319", "target": "species_10075316" }, { "type": "product", "sub_type": "", "source": "reaction_10075319", "target": "species_68454" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075319", "target": "species_10036890" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075312", "target": "reaction_10075319" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58DH8", "target": "species_10075312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000071", "target": "Q58DH8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000071", "target": "species_10036890" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086350", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086350", "target": "species_189254" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_189227", "target": "reaction_10086350" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188995", "target": "species_189227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_188995", "target": "species_189254" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086347", "target": "reaction_10086350" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084455", "target": "species_10086347" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057350", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057347", "target": "reaction_10057350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY6", "target": "species_10057347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003307", "target": "Q2KHY6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS4", "target": "species_10057347" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS4", "target": "species_10044615" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS4", "target": "species_10044619" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021523", "target": "A2VDS4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKR6", "target": "species_10057347" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKR6", "target": "species_10044615" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKR6", "target": "species_10044619" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046676", "target": "E1BKR6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057399", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057396", "target": "reaction_10057399" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N684", "target": "species_10057396" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081253", "target": "A0A3Q1N684" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10033473", "target": "species_10033471" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033469", "target": "reaction_10033473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084497", "target": "species_8857850" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084497", "target": "species_29478" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084497", "target": "species_159942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10084497", "target": "species_159939" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8857725", "target": "reaction_10084497" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084494", "target": "reaction_10084497" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5P9", "target": "species_10084494" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081168", "target": "A0A3Q1N5P9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ48", "target": "species_10084494" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034976", "target": "A0A452DJ48" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090466", "target": "species_9025151" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025155", "target": "reaction_10090466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025155", "target": "reaction_10090468" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:138674", "target": "species_9025151" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:138673", "target": "species_9025151" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090466" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090470" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090460" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090394" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090462" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090396" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10064558", "target": "reaction_10090382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090468", "target": "species_9025960" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090477", "target": "species_9026407" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090470", "target": "species_9026047" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090472", "target": "species_9026293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090474", "target": "species_9026307" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090474", "target": "species_29364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025012", "target": "reaction_10090474" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9025012", "target": "reaction_10090464" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052888", "target": "species_10052886" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052876", "target": "reaction_10052888" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10052876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10052886" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10052903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10052905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10052872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10076097" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIG6", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046421", "target": "E1BIG6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052886", "target": "reaction_10052909" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052923", "target": "species_71067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_917810", "target": "reaction_10052923" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10052920", "target": "reaction_10052923" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052907", "target": "species_10052905" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052903", "target": "reaction_10052907" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052905", "target": "reaction_10052911" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052925", "target": "species_10052876" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052874", "target": "reaction_10052925" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052872", "target": "reaction_10052925" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052872", "target": "reaction_10076099" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052909", "target": "species_10052903" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052909", "target": "species_917966" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10052911", "target": "species_10051000" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052911", "target": "species_10052872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076099", "target": "species_10076097" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076095", "target": "reaction_10076099" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017371", "target": "species_10076095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017371", "target": "Q5EEZ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EEZ1", "target": "species_10076097" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052901", "target": "species_917810" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_917882", "target": "reaction_10052901" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052898", "target": "reaction_10052901" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036076", "target": "species_10036074" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036050", "target": "reaction_10036076" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036052", "target": "species_10036050" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036048", "target": "reaction_10036052" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036044", "target": "reaction_10036052" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036044", "target": "reaction_10036917" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085967", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085967", "target": "species_8876304" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8876310", "target": "reaction_10085967" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085964", "target": "reaction_10085967" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029140", "target": "species_10085964" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048768", "target": "species_425425" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048768", "target": "species_352022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_425425", "target": "reaction_10058722" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048765", "target": "reaction_10048768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033777", "target": "species_10048765" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048740", "target": "species_352022" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048737", "target": "reaction_10048740" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BD54", "target": "species_10048737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045797", "target": "E1BD54" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9J2", "target": "species_10048737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001818", "target": "E1B9J2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052040", "target": "species_29432" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052040", "target": "species_893599" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052037", "target": "reaction_10052040" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052037", "target": "reaction_10052043" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052037", "target": "reaction_10052046" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q816", "target": "species_10052037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050582", "target": "F6Q816" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064346", "target": "species_2022135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064346", "target": "species_351629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064346", "target": "species_2160466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064343", "target": "reaction_10064346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N191", "target": "species_10064343" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007580", "target": "F1N191" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033935", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033935", "target": "species_71129" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033932", "target": "reaction_10033935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBD3", "target": "species_10033932" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015750", "target": "Q3ZBD3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076974", "target": "species_29502" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076974", "target": "species_29448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076974", "target": "species_5359061" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076971", "target": "reaction_10076974" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LE5", "target": "species_10076971" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077904", "target": "Q32LE5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033944", "target": "species_31135" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30337", "target": "reaction_10033944" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31135", "target": "reaction_10033953" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033941", "target": "reaction_10033944" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS65", "target": "species_10033941" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087453", "target": "A0A3Q1LS65" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033962", "target": "species_29666" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033962", "target": "species_29586" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_31175", "target": "reaction_10033962" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033959", "target": "reaction_10033962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPJ4", "target": "species_10033959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072597", "target": "A0A3Q1MPJ4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033953", "target": "species_31175" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033950", "target": "reaction_10033953" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075181", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075181", "target": "species_10075178" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035844", "target": "reaction_10075181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE43", "target": "species_10035844" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE43", "target": "species_10075178" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055617", "target": "A2VE43" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055617", "target": "species_10035842" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075170", "target": "reaction_10075181" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075170", "target": "reaction_10088872" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035846", "target": "species_10035844" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035842", "target": "reaction_10035846" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040183", "target": "species_10040181" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040167", "target": "reaction_10040183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026619", "target": "species_10040167" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026619", "target": "A4IFH4" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040179", "target": "reaction_10040183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022773", "target": "species_10040179" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022773", "target": "A2VE40" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040175", "target": "reaction_10040183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012322", "target": "species_10040175" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012322", "target": "Q08E12" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040171", "target": "reaction_10040183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061540", "target": "species_10040171" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061540", "target": "E1BC42" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC42", "target": "species_10040181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E12", "target": "species_10040181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE40", "target": "species_10040181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFH4", "target": "species_10040181" }, { "type": "product", "sub_type": "", "source": "reaction_10033504", "target": "species_69172" }, { "type": "reactant", "sub_type": "", "source": "species_68452", "target": "reaction_10033504" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038904", "target": "species_10038902" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038900", "target": "reaction_10038904" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063305", "target": "species_10038900" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063305", "target": "G3N2I6" }, { "type": "reactant", "sub_type": "", "source": "species_164569", "target": "reaction_10038904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2I6", "target": "species_10038902" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10040864", "target": "species_10040862" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055833", "target": "species_10055579" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055577", "target": "reaction_10055833" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023059", "target": "species_10055577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023059", "target": "F1N0Y3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0Y3", "target": "species_10055579" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0Y3", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0Y3", "target": "species_10055641" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055515", "target": "species_10055513" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055511", "target": "reaction_10055515" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055501", "target": "reaction_10055515" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10055645", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055645", "target": "species_10055643" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055643", "target": "reaction_10055645" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF29", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF29", "target": "species_10055561" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF29", "target": "species_10055641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012347", "target": "E1BF29" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012347", "target": "species_10055559" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG49", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG49", "target": "species_10055641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG49", "target": "species_10055567" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011898", "target": "E1BG49" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011898", "target": "species_10055565" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCP5", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCP5", "target": "species_10055641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCP5", "target": "species_10055825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCP5", "target": "species_10055555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076641", "target": "F1MCP5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG61", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG61", "target": "species_10055641" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG61", "target": "species_10055825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MG61", "target": "species_10055555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076936", "target": "A0A3Q1MG61" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC41", "target": "species_10055643" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC41", "target": "species_10055641" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060943", "target": "E1BC41" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055823", "target": "species_10055561" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055559", "target": "reaction_10055823" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055647", "target": "species_10055643" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055641", "target": "reaction_10055647" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055827", "target": "species_10055555" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055825", "target": "reaction_10055827" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055829", "target": "species_10055567" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055565", "target": "reaction_10055829" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055831", "target": "species_10055535" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055533", "target": "reaction_10055831" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090460", "target": "species_9024883" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024012", "target": "reaction_10090460" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024012", "target": "reaction_10090462" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024012", "target": "reaction_10090390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090386", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090386", "target": "species_9024893" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024522", "target": "reaction_10090386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024522", "target": "reaction_10090388" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090708", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090708", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090708", "target": "species_9037755" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024886", "target": "reaction_10090708" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090705", "target": "reaction_10090708" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091753", "target": "species_10085164" }, { "type": "reactant", "sub_type": "other", "source": "species_9648300", "target": "reaction_10091753" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084440", "target": "reaction_10091753" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084440", "target": "reaction_10085166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVF9", "target": "species_10084440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVF9", "target": "species_10085164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVF9", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074327", "target": "A0A3Q1LVF9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DS7", "target": "species_10084440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DS7", "target": "species_10085164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DS7", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076585", "target": "Q08DS7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCG7", "target": "species_10084440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCG7", "target": "species_10085164" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCG7", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050604", "target": "A0A3Q1MCG7" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10085164", "target": "reaction_10085166" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084824", "target": "species_10084779" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084753", "target": "reaction_10084824" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084753", "target": "reaction_10084757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWJ5", "target": "species_10084753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWJ5", "target": "species_10084779" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWJ5", "target": "species_10084817" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MWJ5", "target": "species_10084755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082605", "target": "A0A3Q1MWJ5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075931", "target": "reaction_10084824" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084779", "target": "reaction_10084819" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085116", "target": "species_10085114" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085112", "target": "reaction_10085116" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085166", "target": "species_10085162" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085160", "target": "reaction_10085166" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11456", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11456", "target": "species_10085162" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11456", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11456", "target": "species_10083333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11456", "target": "species_10083323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067687", "target": "P11456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK36", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK36", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019955", "target": "E1BK36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJK4", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJK4", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037742", "target": "F1MJK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L97", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L97", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071023", "target": "Q32L97" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPN6", "target": "species_10085160" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPN6", "target": "species_10085162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014549", "target": "A0A3S5ZPN6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085134", "target": "species_10085132" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085126", "target": "reaction_10085134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E628", "target": "species_10085126" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E628", "target": "species_10085132" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029117", "target": "G5E628" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085130", "target": "reaction_10085134" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084618", "target": "species_10085130" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084618", "target": "A0A3Q1MSK9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSK9", "target": "species_10085132" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085264", "target": "species_10085262" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085260", "target": "reaction_10085264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKA6", "target": "species_10085260" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NKA6", "target": "species_10085262" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070874", "target": "A0A3Q1NKA6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084819", "target": "species_10084817" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084793", "target": "reaction_10084819" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQM0", "target": "species_10084793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQM0", "target": "species_10084817" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080374", "target": "A0A3Q1MQM0" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084817", "target": "reaction_10084822" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084757", "target": "species_10084755" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084743", "target": "reaction_10084757" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZP6", "target": "species_10084743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZP6", "target": "species_10084755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081053", "target": "A0A3Q1LZP6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXE7", "target": "species_10084743" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LXE7", "target": "species_10084755" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080553", "target": "A0A3Q1LXE7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084822", "target": "species_10084753" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084822", "target": "species_10084815" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084822", "target": "species_10075931" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084822", "target": "species_10084793" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089048", "target": "species_10089046" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089044", "target": "reaction_10089048" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02192", "target": "species_10089044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02192", "target": "species_10089046" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084629", "target": "P02192" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089046", "target": "reaction_10089062" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089058", "target": "species_10089056" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089054", "target": "reaction_10089058" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6WZ19", "target": "species_10089054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6WZ19", "target": "species_10089056" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021661", "target": "Q6WZ19" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089056", "target": "reaction_10089060" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089060", "target": "species_29368" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089060", "target": "species_10089054" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089062", "target": "species_10089044" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089062", "target": "species_29368" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049869", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049869", "target": "species_140912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140912", "target": "reaction_10049628" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140912", "target": "reaction_10049871" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049625", "target": "reaction_10049869" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049625", "target": "reaction_10049628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080155", "target": "species_10049625" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049628", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049628", "target": "species_31633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049871", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049871", "target": "species_31633" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049632", "target": "reaction_10049871" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049632", "target": "reaction_10049635" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050191", "target": "species_10049632" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049635", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049635", "target": "species_140912" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049371", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049371", "target": "species_71067" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_435347", "target": "reaction_10049371" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049368", "target": "reaction_10049371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068742", "target": "species_10049368" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049402", "target": "species_209799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_437295", "target": "reaction_10049402" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049399", "target": "reaction_10049402" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072292", "target": "species_10049399" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049378", "target": "species_158417" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049375", "target": "reaction_10049378" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014489", "target": "species_10049375" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088912", "target": "species_266099" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29418", "target": "reaction_10088912" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29418", "target": "reaction_10076172" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088909", "target": "reaction_10088912" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005787", "target": "species_10088909" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049358", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049358", "target": "species_446597" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_446589", "target": "reaction_10049358" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8428", "target": "species_446589" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:8428", "target": "species_446597" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049355", "target": "reaction_10049358" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074816", "target": "species_10049355" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049060", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049060", "target": "species_426910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_429130", "target": "reaction_10049060" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049057", "target": "reaction_10049060" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061504", "target": "species_10049057" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049078", "target": "species_83910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049078", "target": "species_429648" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_429652", "target": "reaction_10049078" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27372", "target": "species_429652" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27372", "target": "species_429648" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049075", "target": "reaction_10049078" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004510", "target": "species_10049075" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049592", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049592", "target": "species_113538" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049592", "target": "species_352022" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049589", "target": "reaction_10049592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035184", "target": "species_10049589" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049613", "target": "species_444152" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_444154", "target": "reaction_10049613" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049610", "target": "reaction_10049613" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045811", "target": "species_10049610" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049599", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049599", "target": "species_352022" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049599", "target": "species_29424" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049596", "target": "reaction_10049599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087022", "target": "species_10049596" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049319", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049319", "target": "species_176483" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_433120", "target": "reaction_10049319" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049316", "target": "reaction_10049319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066284", "target": "species_10049316" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049606", "target": "species_29514" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_432019", "target": "reaction_10049606" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_432019", "target": "reaction_10051150" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049603", "target": "reaction_10049606" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002712", "target": "species_10049603" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049080", "target": "species_429627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049080", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_429605", "target": "reaction_10049080" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16494", "target": "species_429605" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16494", "target": "species_429627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051577", "target": "species_914003" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051574", "target": "reaction_10051577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051574", "target": "reaction_10051580" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004376", "target": "species_10051574" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051580", "target": "species_742361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_742353", "target": "reaction_10051580" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051587", "target": "species_113578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051587", "target": "species_744233" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_744239", "target": "reaction_10051587" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039874", "target": "species_3499326" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039874", "target": "species_174384" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158601", "target": "reaction_10039874" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174384", "target": "reaction_10039916" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174384", "target": "reaction_10038336" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174384", "target": "reaction_10038338" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039871", "target": "reaction_10039874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VE55", "target": "species_10039871" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051899", "target": "species_879517" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_879521", "target": "reaction_10051899" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051896", "target": "reaction_10051899" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051866", "target": "species_879628" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_879603", "target": "reaction_10051866" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_879603", "target": "reaction_10091250" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051863", "target": "reaction_10051866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC23", "target": "species_10051863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026117", "target": "E1BC23" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPV8", "target": "species_10051863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021795", "target": "E1BPV8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MM56", "target": "species_10051863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003345", "target": "F1MM56" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MYV0", "target": "species_10051863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030217", "target": "F1MYV0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030217", "target": "species_10051847" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030217", "target": "species_10091602" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051843", "target": "species_879614" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_879566", "target": "reaction_10051843" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15544", "target": "species_879566" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15544", "target": "species_879614" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15544", "target": "species_10051868" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15544", "target": "species_10051872" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051840", "target": "reaction_10051843" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001747", "target": "species_10051840" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091250", "target": "species_879628" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051847", "target": "reaction_10091250" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051847", "target": "reaction_10091598" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051879", "target": "species_10051872" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051868", "target": "reaction_10051879" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051876", "target": "reaction_10051879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000055950", "target": "species_10051876" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070928", "target": "species_10070926" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070924", "target": "reaction_10070928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ62", "target": "species_10070924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ62", "target": "species_10070926" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084009", "target": "A0A3Q1LZ62" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Y3", "target": "species_10070924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9Y3", "target": "species_10070926" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032576", "target": "E1B9Y3" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5229279", "target": "reaction_10070928" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5229279", "target": "species_10070926" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051892", "target": "species_879544" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_879559", "target": "reaction_10051892" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051889", "target": "reaction_10051892" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCQ2", "target": "species_10051889" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020526", "target": "Q0VCQ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQD5", "target": "species_10051889" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044112", "target": "A6QQD5" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036297", "target": "species_179741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036297", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_179740", "target": "reaction_10036297" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179741" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_500172" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_500104" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_500118" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17596", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179741" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_500104" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_500245" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_500118" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16750", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179741" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179738" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500759" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500318" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500415" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16704", "target": "species_500346" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036294", "target": "reaction_10036297" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021720", "target": "species_10036294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051545", "target": "species_727737" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_727774", "target": "reaction_10051545" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_727737", "target": "reaction_10051547" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051542", "target": "reaction_10051545" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10051542", "target": "reaction_10051547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010219", "target": "species_10051542" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071001", "target": "species_10070983" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070999", "target": "reaction_10071001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA37", "target": "species_10070999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA37", "target": "species_10070983" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA37", "target": "species_10070995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TA37", "target": "species_10070989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002890", "target": "Q2TA37" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PC9", "target": "species_10070999" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PC9", "target": "species_10070983" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32PC9", "target": "species_10070989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006363", "target": "Q32PC9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006363", "target": "species_10070997" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070983", "target": "reaction_10070991" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036283", "target": "species_179739" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036283", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_179738", "target": "reaction_10036283" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179738" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_179742" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83928", "target": "reaction_10035020" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_500822" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_500421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_500318" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_500415" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83928", "target": "species_500346" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179738" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179737" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179743" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_500759" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_500829" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_500318" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17562", "target": "species_500346" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_179738" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_179739" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_500104" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_500224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_500173" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17256", "target": "species_500201" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036280", "target": "reaction_10036283" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075356", "target": "species_10036280" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051547", "target": "species_727774" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071003", "target": "species_10070999" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070997", "target": "reaction_10071003" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070995", "target": "reaction_10071003" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070991", "target": "species_10070989" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070987", "target": "reaction_10070991" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017580", "target": "species_10070987" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017580", "target": "P02722" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070989", "target": "reaction_10073838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02722", "target": "species_10070989" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073838", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073838", "target": "species_113592" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036290", "target": "species_179743" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036290", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_179737", "target": "reaction_10036290" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036287", "target": "reaction_10036290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024328", "target": "species_10036287" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036274", "target": "species_179742" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_179747", "target": "reaction_10036274" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83956", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83956", "target": "species_179742" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83956", "target": "reaction_10035464" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_83956", "target": "reaction_10035455" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_83956", "target": "species_500259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29850", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29850", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29850", "target": "species_500259" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5635947", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5635947", "target": "species_179742" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16040", "target": "species_179747" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16040", "target": "species_179742" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_179742", "target": "reaction_10036276" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036271", "target": "reaction_10036274" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036271", "target": "reaction_10036276" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015948", "target": "species_10036271" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036276", "target": "species_179747" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038660", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038660", "target": "species_113592" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038657", "target": "reaction_10038660" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32007", "target": "species_10038657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063682", "target": "P32007" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048747", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048747", "target": "species_83910" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048744", "target": "reaction_10048747" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010384", "target": "species_10048744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085896", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085896", "target": "species_113552" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085893", "target": "reaction_10085896" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001624", "target": "species_10085893" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049083", "target": "species_209785" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049083", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060218", "target": "species_113544" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060218", "target": "species_174375" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614584", "target": "reaction_10060218" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048821", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048821", "target": "species_428614" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428548", "target": "reaction_10048821" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_428548", "target": "reaction_10048965" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048818", "target": "reaction_10048821" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV52", "target": "species_10048818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009255", "target": "A4FV52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLI1", "target": "species_10048818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007935", "target": "A6QLI1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BA07", "target": "species_10048818" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001445", "target": "E1BA07" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049173", "target": "species_209818" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048601", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048601", "target": "species_352022" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048598", "target": "reaction_10048601" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076302", "target": "species_10048598" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048618", "target": "species_74126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048618", "target": "species_188972" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048615", "target": "reaction_10048618" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCI8", "target": "species_10048615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024019", "target": "E1BCI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPL9", "target": "species_10048615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018852", "target": "A0A3S5ZPL9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NIV4", "target": "species_10048615" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082311", "target": "A0A3Q1NIV4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048594", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048594", "target": "species_83910" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048594", "target": "species_352022" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048591", "target": "reaction_10048594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046583", "target": "species_10048591" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048795", "target": "species_428026" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048795", "target": "species_70106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_428037", "target": "reaction_10048795" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:90799", "target": "species_428037" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:90799", "target": "species_428026" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:90799", "target": "species_427984" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:47923", "target": "species_428037" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:47923", "target": "species_428026" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048792", "target": "reaction_10048795" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001891", "target": "species_10048792" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048802", "target": "species_70106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048802", "target": "species_428003" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_427984", "target": "reaction_10048802" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46761", "target": "species_428003" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048799", "target": "reaction_10048802" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030236", "target": "species_10048799" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048965", "target": "species_428632" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048965", "target": "species_70106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_428592", "target": "reaction_10048965" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10048962", "target": "reaction_10048965" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048804", "target": "species_74126" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048804", "target": "species_427997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048804", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048804", "target": "species_83910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_428027", "target": "reaction_10048804" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17364", "target": "species_428027" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17364", "target": "species_427997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048491", "target": "species_425425" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048491", "target": "species_74113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048488", "target": "reaction_10048491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBH7", "target": "species_10048488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006425", "target": "E1BBH7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIN2", "target": "species_10048488" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029024", "target": "E1BIN2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048478", "target": "species_425425" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10048478", "target": "species_352022" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10048475", "target": "reaction_10048478" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKK3", "target": "species_10048475" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019936", "target": "E1BKK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M051", "target": "species_10048475" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071207", "target": "A0A3Q1M051" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049053", "target": "species_70113" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049050", "target": "reaction_10049053" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066412", "target": "species_10049050" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089038", "target": "species_70113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089035", "target": "reaction_10089038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q27994", "target": "species_10089035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012109", "target": "Q27994" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089024", "target": "species_70113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089021", "target": "reaction_10089024" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA30", "target": "species_10089021" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042945", "target": "A0A3Q1MA30" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085907", "target": "species_70113" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085904", "target": "reaction_10085907" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010116", "target": "species_10085904" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089029", "target": "species_70113" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10089026", "target": "reaction_10089029" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049046", "target": "species_429148" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_429078", "target": "reaction_10049046" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049043", "target": "reaction_10049046" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079223", "target": "species_10049043" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037913", "target": "species_10037859" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037913", "target": "species_10037807" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037857", "target": "reaction_10037913" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037857", "target": "reaction_10037887" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037807", "target": "reaction_10037937" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037807", "target": "reaction_10037906" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037807", "target": "reaction_10037815" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037910", "target": "reaction_10037913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P30931", "target": "species_10037910" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P30931", "target": "species_10037884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P30931", "target": "species_10037935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009341", "target": "P30931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009341", "target": "species_10037897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009341", "target": "species_10037864" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22457", "target": "species_10037910" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22457", "target": "species_10037903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22457", "target": "species_10037884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22457", "target": "species_10037935" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P22457", "target": "species_10037893" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037899", "target": "species_10037864" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037897", "target": "reaction_10037899" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037864", "target": "reaction_10037915" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037864", "target": "reaction_10037895" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037915", "target": "species_10037910" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037903", "target": "reaction_10037915" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037903", "target": "reaction_10037906" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037887", "target": "species_10037859" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037887", "target": "species_10037807" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037884", "target": "reaction_10037887" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037884", "target": "reaction_10037937" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037937", "target": "species_10037935" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037931", "target": "reaction_10037937" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085417", "target": "species_10037931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085417", "target": "A0A3Q1NLA0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NLA0", "target": "species_10037935" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037906", "target": "species_10037893" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037893", "target": "reaction_10037895" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037895", "target": "species_10037884" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048635", "target": "species_426221" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_426219", "target": "reaction_10048635" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037607", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037604", "target": "reaction_10037607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9U1", "target": "species_10037604" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9U1", "target": "species_10037602" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014321", "target": "Q5E9U1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF3", "target": "species_10037604" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF3", "target": "species_10037602" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020298", "target": "F1MUF3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B742", "target": "species_10037604" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B742", "target": "species_10037602" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025626", "target": "E1B742" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044680", "target": "species_10044678" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044676", "target": "reaction_10044680" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P40673", "target": "species_10044676" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P40673", "target": "species_10044678" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020096", "target": "P40673" }, { "type": "reactant", "sub_type": "", "source": "species_29428", "target": "reaction_10044680" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044142", "target": "species_10044140" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044132", "target": "reaction_10044142" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC37", "target": "species_10044132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC37", "target": "species_10044140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC37", "target": "species_10044108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC37", "target": "species_10044122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017999", "target": "Q0VC37" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017999", "target": "species_10044098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017999", "target": "species_10044106" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017999", "target": "species_10044104" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017999", "target": "species_10044120" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2E0", "target": "species_10044132" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2E0", "target": "species_10044140" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2E0", "target": "species_10044108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2E0", "target": "species_10044122" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N2E0", "target": "species_10044114" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026657", "target": "F1N2E0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026657", "target": "species_10044094" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026657", "target": "species_10044118" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044144", "target": "species_10044098" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044144", "target": "species_10044094" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044144", "target": "species_10044106" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044144", "target": "species_10044104" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044108", "target": "reaction_10044144" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044094", "target": "reaction_10044116" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044146", "target": "species_10044122" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044118", "target": "reaction_10044146" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044120", "target": "reaction_10044146" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044116", "target": "species_10044114" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066489", "target": "species_10066482" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066480", "target": "reaction_10066489" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026496", "target": "species_10066480" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026496", "target": "F1N3C9" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066482", "target": "reaction_10066487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3C9", "target": "species_10066482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3C9", "target": "species_10066484" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065938", "target": "species_10065936" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065934", "target": "reaction_10065938" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021808", "target": "species_10065934" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021808", "target": "species_10065936" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066487", "target": "species_10066484" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066487", "target": "species_10056243" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084216", "target": "species_10084098" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054914", "target": "reaction_10084216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10054914", "target": "reaction_10084214" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039822", "target": "reaction_10084216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039822", "target": "reaction_10076091" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043871", "target": "reaction_10084216" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039818", "target": "reaction_10084216" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084098", "target": "reaction_10084102" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084206", "target": "species_10084203" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084100", "target": "reaction_10084206" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084102", "target": "species_10084100" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084214", "target": "species_10084209" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084211", "target": "reaction_10084214" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039612", "target": "species_10039610" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039608", "target": "reaction_10039612" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075264", "target": "species_10039608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075264", "target": "species_10039610" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10039610", "target": "reaction_10039614" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039614", "target": "species_10039608" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084043", "target": "species_10084041" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084039", "target": "reaction_10084043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009339", "target": "species_10084039" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009339", "target": "species_10084041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009339", "target": "species_10084024" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009339", "target": "F6Q0H8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084041", "target": "reaction_10084047" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084028", "target": "species_10084026" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084024", "target": "reaction_10084028" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q0H8", "target": "species_10084026" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q0H8", "target": "species_10084045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q0H8", "target": "species_10084049" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084047", "target": "species_10084045" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084045", "target": "reaction_10084051" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084051", "target": "species_10084049" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087635", "target": "species_10087633" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039037", "target": "reaction_10087635" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10039037", "target": "reaction_10039049" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII8", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII8", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII8", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII8", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017710", "target": "A0A452DII8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05631", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05631", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05631", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05631", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081996", "target": "P05631" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05630", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05630", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05630", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05630", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000721", "target": "P05630" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05632", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05632", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05632", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P05632", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085877", "target": "P05632" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03929", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03929", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03929", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P03929", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060553", "target": "P03929" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP66", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP66", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP66", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP66", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072644", "target": "A0A3Q1MP66" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00847", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00847", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00847", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00847", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060539", "target": "P00847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC75", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC75", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC75", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC75", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003832", "target": "Q3ZC75" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13620", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13620", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13620", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13620", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074726", "target": "P13620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7G3", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7G3", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7G3", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7G3", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077018", "target": "A0A3Q1M7G3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077018", "target": "A0A3Q1MCR1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077018", "target": "A0A3Q1N4G2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCR1", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCR1", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCR1", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCR1", "target": "species_10039041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4G2", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4G2", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4G2", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N4G2", "target": "species_10039041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q00361", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q00361", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q00361", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q00361", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023255", "target": "Q00361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0N4STN0", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0N4STN0", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0N4STN0", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A0N4STN0", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009643", "target": "A0A0N4STN0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI29", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI29", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI29", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI29", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007538", "target": "A0A452DI29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32876", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32876", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32876", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P32876", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024402", "target": "P32876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13621", "target": "species_10039037" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13621", "target": "species_10087633" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13621", "target": "species_10039039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P13621", "target": "species_10039041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024326", "target": "P13621" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052963", "target": "species_10052961" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10052929", "target": "reaction_10052963" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027868", "target": "species_10052929" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027868", "target": "E1BEK9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10052959", "target": "reaction_10052963" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MH45", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MH45", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MH45", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MH45", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017703", "target": "A0A3Q1MH45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q087", "target": "species_10052959" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q087", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q087", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q087", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004656", "target": "F6Q087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK9", "target": "species_10052961" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK9", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK9", "target": "species_10053041" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083789", "target": "species_10083787" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083783", "target": "reaction_10083789" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083785", "target": "reaction_10083789" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083785", "target": "reaction_10083793" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZS2", "target": "species_10083785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZS2", "target": "species_10083787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZS2", "target": "species_10083791" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063750", "target": "G3MZS2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDP0", "target": "species_10083785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDP0", "target": "species_10083787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDP0", "target": "species_10083791" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023907", "target": "E1BDP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJL8", "target": "species_10083785" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJL8", "target": "species_10083787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJL8", "target": "species_10083791" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJL8", "target": "species_10084354" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053062", "target": "F1MJL8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053062", "target": "species_10083779" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083793", "target": "species_10083791" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084356", "target": "species_10084354" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083779", "target": "reaction_10084356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087862", "target": "species_10087860" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087858", "target": "reaction_10087862" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1G2", "target": "species_10087858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1G2", "target": "species_10087860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1G2", "target": "species_10063396" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1G2", "target": "species_10063398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N1G2", "target": "species_10063388" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067627", "target": "A0A3Q1N1G2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067627", "target": "species_10063386" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M163", "target": "species_10087858" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M163", "target": "species_10087860" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M163", "target": "species_10063396" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M163", "target": "species_10063398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M163", "target": "species_10085759" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074335", "target": "A0A3Q1M163" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074335", "target": "species_10063394" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087997", "target": "species_10053052" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087997", "target": "species_10087995" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087908", "target": "reaction_10087997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32S26", "target": "species_10087908" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32S26", "target": "species_10087995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32S26", "target": "species_10087906" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32S26", "target": "species_10088001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014704", "target": "Q32S26" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056568", "target": "reaction_10087997" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087900", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087900", "target": "species_10087897" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087887", "target": "reaction_10087900" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087897", "target": "reaction_10087910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087889", "target": "species_10087887" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084945", "target": "reaction_10087889" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087910", "target": "species_10087908" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087906", "target": "reaction_10087910" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088006", "target": "species_10087906" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088006", "target": "species_10088003" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088006", "target": "species_427486" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088001", "target": "reaction_10088006" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088012", "target": "species_10088010" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086231", "target": "species_10086229" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086227", "target": "reaction_10086231" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019489", "target": "species_10086227" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019489", "target": "E1BPV9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPV9", "target": "species_10086229" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086587", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086587", "target": "species_10057248" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086587", "target": "species_10086584" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086579", "target": "reaction_10086587" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088490", "target": "species_10088485" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088487", "target": "reaction_10088490" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086589", "target": "species_10084943" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086577", "target": "reaction_10086589" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086577", "target": "reaction_10086581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084947", "target": "species_10084945" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084939", "target": "reaction_10084947" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088482", "target": "species_10088480" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088478", "target": "reaction_10088482" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086581", "target": "species_10086579" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040059", "target": "species_10040056" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040054", "target": "reaction_10040059" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10040056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LY33", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085991", "target": "A0A3Q1LY33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10040056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1J3", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071469", "target": "A0A3Q1M1J3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10040056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBV1", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014278", "target": "Q2TBV1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNK6", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNK6", "target": "species_10040056" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002682", "target": "A6QNK6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10040056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KI86", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008174", "target": "Q2KI86" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10040054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10040056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ11", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017525", "target": "Q3SZ11" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040050", "target": "reaction_10040059" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW1", "target": "species_10040050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFW1", "target": "species_10040056" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024392", "target": "F1MFW1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG06", "target": "species_10040050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG06", "target": "species_10040056" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017599", "target": "E1BG06" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB72", "target": "species_10040050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB72", "target": "species_10040056" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025568", "target": "E1BB72" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040955", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040955", "target": "species_10040952" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040945", "target": "reaction_10040955" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040961", "target": "species_10040945" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040959", "target": "reaction_10040961" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040967", "target": "species_10040965" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040965", "target": "reaction_10040967" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085313", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085313", "target": "species_179856" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060424", "target": "reaction_10085313" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083179", "target": "species_10083177" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083175", "target": "reaction_10083179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFF9", "target": "species_10083175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFF9", "target": "species_10083177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020327", "target": "E1BFF9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJZ4", "target": "species_10083175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJZ4", "target": "species_10083177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004036", "target": "E1BJZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPM7", "target": "species_10083175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPM7", "target": "species_10083177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082501", "target": "A0A3Q1MPM7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUW6", "target": "species_10083175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUW6", "target": "species_10083177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046850", "target": "F1MUW6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083141", "target": "reaction_10083179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ3", "target": "species_10083141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ3", "target": "species_10083177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RMQ3", "target": "species_10083128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006825", "target": "Q1RMQ3" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006825", "target": "species_10083119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LJ2", "target": "species_10083141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LJ2", "target": "species_10083177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LJ2", "target": "species_10083147" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LJ2", "target": "species_10083128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009858", "target": "Q32LJ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2YDM1", "target": "species_10083141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2YDM1", "target": "species_10083177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2YDM1", "target": "species_10083135" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2YDM1", "target": "species_10083185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015767", "target": "Q2YDM1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083149", "target": "species_10083128" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083119", "target": "reaction_10083149" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083147", "target": "reaction_10083149" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083128", "target": "reaction_10083143" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083340", "target": "species_10083335" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083340", "target": "species_10083333" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10083340", "target": "species_10083337" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083331", "target": "reaction_10083340" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA50", "target": "species_10083331" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA50", "target": "species_10083333" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA50", "target": "species_10083323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074576", "target": "Q5EA50" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10083337", "target": "reaction_10083547" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083342", "target": "species_10083331" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083323", "target": "reaction_10083342" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083187", "target": "species_10083185" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10083183", "target": "reaction_10083187" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065986", "target": "species_10083183" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065986", "target": "A0A3Q1M9K7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083135", "target": "reaction_10083187" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083135", "target": "reaction_10083143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9K7", "target": "species_10083185" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083143", "target": "species_10083141" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083451", "target": "species_10083449" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060581", "target": "reaction_10083451" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060581", "target": "reaction_10083425" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083439", "target": "reaction_10083451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM77", "target": "species_10083439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM77", "target": "species_10083449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LM77", "target": "species_10083455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084376", "target": "A0A3Q1LM77" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9S8", "target": "species_10083439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9S8", "target": "species_10083449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9S8", "target": "species_10083455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086938", "target": "A0A3Q1M9S8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS50", "target": "species_10083439" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS50", "target": "species_10083449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS50", "target": "species_10083455" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086695", "target": "A0A3Q1LS50" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083449", "target": "reaction_10083458" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083425", "target": "species_10083423" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083421", "target": "reaction_10083425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ84", "target": "species_10083421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ84", "target": "species_10083423" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ84", "target": "species_10072269" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084706", "target": "A0A3Q1MQ84" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084706", "target": "species_10072267" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083056", "target": "species_10083054" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082114", "target": "reaction_10083056" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10082114", "target": "reaction_10083767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK29", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK29", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK29", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007999", "target": "E1BK29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ89", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ89", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MQ89", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027073", "target": "F1MQ89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKB6", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKB6", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DKB6", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045677", "target": "A0A452DKB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGA6", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGA6", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGA6", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023803", "target": "E1BGA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R4", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R4", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5R4", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002179", "target": "F1N5R4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHG0", "target": "species_10082114" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHG0", "target": "species_10083054" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHG0", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017269", "target": "Q3MHG0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083052", "target": "reaction_10083056" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA6", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDA6", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027499", "target": "F1MDA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIQ3", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIQ3", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005055", "target": "E1BIQ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE3", "target": "species_10083052" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTE3", "target": "species_10083054" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075149", "target": "A0A3Q1LTE3" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083458", "target": "species_10083455" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083767", "target": "species_10083765" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10083763", "target": "reaction_10083767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ06", "target": "species_10083763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ06", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017437", "target": "E1BJ06" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M591", "target": "species_10083763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M591", "target": "species_10083765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073539", "target": "A0A3Q1M591" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065827", "target": "species_10065825" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065823", "target": "reaction_10065827" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045309", "target": "species_10065823" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045309", "target": "F1MZM9" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1297302", "target": "reaction_10065827" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1297302", "target": "species_10065825" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZM9", "target": "species_10065825" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047292", "target": "species_10047290" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047270", "target": "reaction_10047292" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10047288", "target": "reaction_10047292" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060207", "target": "species_1614518" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060207", "target": "species_29356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174369", "target": "reaction_10060207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174369", "target": "reaction_10060275" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174369", "target": "reaction_10060255" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_174369", "target": "reaction_10060228" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174369", "target": "reaction_10077124" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614518", "target": "reaction_10060231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060204", "target": "reaction_10060207" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MEW4", "target": "species_10060204" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087445", "target": "F1MEW4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060231", "target": "species_111707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060231", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060231", "target": "species_936714" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060225", "target": "reaction_10060231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060225", "target": "reaction_10060252" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060225", "target": "reaction_10060255" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060225", "target": "reaction_10060234" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060225", "target": "reaction_10060228" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2L1", "target": "species_10060225" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005788", "target": "A0A3Q1M2L1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060275", "target": "species_174390" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060275", "target": "species_1614585" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060272", "target": "reaction_10060275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHV7", "target": "species_10060272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002916", "target": "A0A452DHV7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057032", "target": "species_1237165" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057032", "target": "species_83951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_353106", "target": "reaction_10057032" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83951", "target": "reaction_10035435" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057029", "target": "reaction_10057032" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHF7", "target": "species_10057029" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048509", "target": "Q3MHF7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057023", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057023", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057023", "target": "species_1237155" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1237176", "target": "reaction_10057023" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057020", "target": "reaction_10057023" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VD27", "target": "species_10057020" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019702", "target": "Q0VD27" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057684", "target": "species_1237165" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1237107", "target": "reaction_10057684" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10057011", "target": "reaction_10057684" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003273", "target": "species_10057011" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090681", "target": "species_10089847" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090681", "target": "species_10067705" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090681", "target": "species_1655881" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090677", "target": "reaction_10090681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9D2", "target": "species_10090677" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069079", "target": "A0A3Q1M9D2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069079", "target": "species_10089847" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069079", "target": "species_10090669" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q95108", "target": "species_10090677" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089847", "target": "reaction_10089850" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089847", "target": "reaction_10090013" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089847", "target": "reaction_10090015" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089847", "target": "reaction_10090671" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089850", "target": "species_1614595" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089850", "target": "species_113557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9012724", "target": "reaction_10089850" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9012592", "target": "reaction_10089850" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9012592", "target": "reaction_10090013" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9012592", "target": "reaction_10090671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614595", "target": "reaction_10060361" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614595", "target": "reaction_10089959" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090013", "target": "species_9013191" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090013", "target": "species_113557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9013199", "target": "reaction_10090013" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9013199", "target": "reaction_10090015" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9013199", "target": "reaction_10089959" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060252", "target": "species_1614532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060252", "target": "species_200736" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060255", "target": "species_1614532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060255", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060255", "target": "species_936714" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090015", "target": "species_9013191" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090015", "target": "species_113557" }, { "type": "reactant", "sub_type": "other", "source": "species_9013543", "target": "reaction_10090015" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090679", "target": "species_10090677" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090669", "target": "reaction_10090679" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060361", "target": "species_1655882" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060361", "target": "species_1614538" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060361", "target": "species_1655881" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1614538", "target": "reaction_10060216" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060358", "target": "reaction_10060361" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023735", "target": "species_10060358" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060216", "target": "species_1614617" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060216", "target": "species_1614584" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060213", "target": "reaction_10060216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHX0", "target": "species_10060213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008101", "target": "Q3MHX0" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10060250", "target": "species_10060241" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060250", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060250", "target": "species_1614538" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060239", "target": "reaction_10060250" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013690", "target": "species_10060239" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013690", "target": "species_10060241" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060247", "target": "reaction_10060250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3T094", "target": "species_10060247" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005747", "target": "Q3T094" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060264", "target": "species_1614519" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060261", "target": "reaction_10060264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCZ5", "target": "species_10060261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079843", "target": "A0A3Q1MCZ5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060234", "target": "species_1614582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060234", "target": "species_1614532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090671", "target": "species_113557" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090671", "target": "species_10090669" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083204", "target": "species_1655445" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083204", "target": "species_70106" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6814151", "target": "reaction_10083204" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083201", "target": "reaction_10083204" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZK0", "target": "species_10083201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064438", "target": "G3MZK0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060228", "target": "species_1614532" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060228", "target": "species_1614594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089959", "target": "species_9013207" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10089959", "target": "species_9013191" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10089956", "target": "reaction_10089959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043317", "target": "species_10089956" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077124", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077124", "target": "species_174390" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_4789070", "target": "reaction_10077124" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077121", "target": "reaction_10077124" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4C6", "target": "species_10077121" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048928", "target": "F1N4C6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078575", "target": "species_159549" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078575", "target": "species_6797920" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6797917", "target": "reaction_10078575" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10078572", "target": "reaction_10078575" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MR10", "target": "species_10078572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075705", "target": "A0A3Q1MR10" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078582", "target": "species_6798194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10078582", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6798162", "target": "reaction_10078582" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10078579", "target": "reaction_10078582" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013227", "target": "species_10078579" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044844", "target": "species_204635" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044844", "target": "species_353106" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_353113", "target": "reaction_10044844" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_353113", "target": "reaction_10044851" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044841", "target": "reaction_10044844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006978", "target": "species_10044841" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10044851", "target": "species_71284" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044851", "target": "species_353113" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044851", "target": "species_113528" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044848", "target": "reaction_10044851" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054971", "target": "species_10044848" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033778", "target": "species_29610" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033778", "target": "species_113528" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033788", "target": "species_29406" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10033788", "target": "species_508182" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033788", "target": "species_29404" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033788", "target": "species_508187" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_508182", "target": "reaction_10033788" }, { "type": "product", "sub_type": "complex_component", "source": "species_508187", "target": "reaction_10033788" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28654", "target": "species_508187" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17865", "target": "species_508187" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16530", "target": "species_508187" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033785", "target": "reaction_10033788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1ML78", "target": "species_10033785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086973", "target": "A0A3Q1ML78" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033806", "target": "species_70772" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10033806", "target": "species_113521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033806", "target": "species_70784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70772", "target": "reaction_10033806" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_70784", "target": "reaction_10033806" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033803", "target": "reaction_10033806" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9N4", "target": "species_10033803" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068139", "target": "A0A3Q1M9N4" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051185", "target": "species_113529" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051185", "target": "species_70836" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051185", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051185", "target": "species_70829" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051185", "target": "species_113526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70836", "target": "reaction_10051185" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70836", "target": "reaction_10033824" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_70829", "target": "reaction_10051185" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033812", "target": "reaction_10051185" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O02691", "target": "species_10033812" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023642", "target": "O02691" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033824", "target": "species_70843" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033824", "target": "species_113559" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033821", "target": "reaction_10033824" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033821", "target": "reaction_10035417" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RZ0", "target": "species_10033821" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017122", "target": "Q29RZ0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033797", "target": "species_70744" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033797", "target": "species_31649" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70715", "target": "reaction_10033797" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033794", "target": "reaction_10033797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI40", "target": "species_10033794" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005782", "target": "A0A452DI40" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052027", "target": "species_33179" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052024", "target": "reaction_10052027" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPE1", "target": "species_10052024" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007525", "target": "E1BPE1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052043", "target": "species_29432" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052043", "target": "species_893615" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29970", "target": "reaction_10052043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29970", "target": "reaction_10033969" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_8939576", "target": "reaction_10052043" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:55528", "target": "species_8939576" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:43580", "target": "species_8939576" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033979", "target": "species_29432" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033979", "target": "species_30487" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_34351", "target": "reaction_10033979" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30487", "target": "reaction_10033988" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033976", "target": "reaction_10033979" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB81", "target": "species_10033976" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069075", "target": "A0A3Q1MB81" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052030", "target": "species_893617" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052030", "target": "species_113552" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_893607", "target": "reaction_10052030" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033856", "target": "reaction_10052030" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033856", "target": "reaction_10051198" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKR3", "target": "species_10033856" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085694", "target": "A0A3Q1LKR3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033969", "target": "species_34351" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033969", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033969", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10033966", "target": "reaction_10033969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073847", "target": "species_10033966" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085381", "target": "species_29500" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033988", "target": "species_36027" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033985", "target": "reaction_10033988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIN3", "target": "species_10033985" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006132", "target": "A0A452DIN3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041894", "target": "species_33179" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041891", "target": "reaction_10041894" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFW8", "target": "species_10041891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070085", "target": "A0A3Q1LFW8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090155", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090155", "target": "species_9014643" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9014643", "target": "reaction_10090162" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090152", "target": "reaction_10090155" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKH5", "target": "species_10090152" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011776", "target": "A5PKH5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090162", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090162", "target": "species_936714" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090159", "target": "reaction_10090162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016718", "target": "species_10090159" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065455", "target": "species_5357660" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065455", "target": "species_29432" }, { "type": "product", "sub_type": "", "source": "reaction_10065455", "target": "species_5359011" }, { "type": "reactant", "sub_type": "", "source": "species_5359016", "target": "reaction_10065455" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5357697", "target": "reaction_10065455" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065452", "target": "reaction_10065455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDS1", "target": "species_10065452" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013719", "target": "A2VDS1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054601", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054601", "target": "species_200736" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_936706", "target": "reaction_10054601" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054598", "target": "reaction_10054601" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHU0", "target": "species_10054598" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017392", "target": "Q2KHU0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054620", "target": "species_977329" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054620", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054620", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_977329", "target": "reaction_10054611" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054617", "target": "reaction_10054620" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T866", "target": "species_10054617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008907", "target": "A0A140T866" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090172", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090172", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090172", "target": "species_29398" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_376186", "target": "reaction_10090172" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090169", "target": "reaction_10090172" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090169", "target": "reaction_10090175" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090169", "target": "reaction_10090647" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNI4", "target": "species_10090169" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005532", "target": "A0JNI4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090175", "target": "species_376186" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054611", "target": "species_29406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10054611", "target": "species_936706" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10054608", "target": "reaction_10054611" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPF7", "target": "species_10054608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018554", "target": "A0A3S5ZPF7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086371", "target": "species_8932979" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086368", "target": "reaction_10086371" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUZ5", "target": "species_10086368" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002833", "target": "A4FUZ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF32", "target": "species_10086368" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072137", "target": "A0A3Q1LF32" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090647", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090647", "target": "species_29382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090647", "target": "species_29398" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051165", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051165", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051165", "target": "species_31339" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051165", "target": "species_113563" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051162", "target": "reaction_10051165" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH7", "target": "species_10051162" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015703", "target": "Q2KJH7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077453", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077453", "target": "species_113538" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_35305", "target": "reaction_10077453" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077450", "target": "reaction_10077453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58D08", "target": "species_10077450" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022364", "target": "Q58D08" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087455", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087455", "target": "species_5693762" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10087452", "target": "reaction_10087455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCE9", "target": "species_10087452" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004262", "target": "Q0VCE9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0M1", "target": "species_10087452" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023262", "target": "F1N0M1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052046", "target": "species_29432" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052046", "target": "species_893598" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077444", "target": "species_113526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077444", "target": "species_379717" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113590", "target": "reaction_10077444" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077441", "target": "reaction_10077444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QJ7", "target": "species_10077441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000047", "target": "Q17QJ7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077864", "target": "species_5696409" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077864", "target": "species_113525" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6788606", "target": "reaction_10077864" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077861", "target": "reaction_10077864" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067508", "target": "species_10077861" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077435", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077435", "target": "species_6783877" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693325", "target": "reaction_10077435" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077432", "target": "reaction_10077435" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010444", "target": "species_10077432" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10045036", "target": "species_113594" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10045036", "target": "species_113577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045036", "target": "species_29406" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10045036", "target": "species_70951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113577", "target": "reaction_10045036" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_70951", "target": "reaction_10045036" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_70951", "target": "reaction_10051198" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045033", "target": "reaction_10045036" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077809", "target": "species_10045033" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051198", "target": "species_70951" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051198", "target": "species_113552" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051198", "target": "species_113594" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051198", "target": "species_508531" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_508531", "target": "reaction_10051198" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076261", "target": "species_5693325" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076261", "target": "species_389556" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693311", "target": "reaction_10076261" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076258", "target": "reaction_10076261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012972", "target": "species_10076258" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033997", "target": "species_113543" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10033997", "target": "species_113586" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113545", "target": "reaction_10033997" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10033994", "target": "reaction_10033997" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ74", "target": "species_10033994" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007338", "target": "Q2HJ74" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042847", "target": "species_200351" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042847", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29916", "target": "reaction_10042847" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29916", "target": "reaction_10042838" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042844", "target": "reaction_10042847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTK8", "target": "species_10042844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009871", "target": "Q9TTK8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034004", "target": "species_29916" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034004", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034004", "target": "species_71285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30401", "target": "reaction_10034004" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034001", "target": "reaction_10034004" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005375", "target": "species_10034001" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042838", "target": "species_200351" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10042838", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10042835", "target": "reaction_10042838" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA61", "target": "species_10042835" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050490", "target": "Q5EA61" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066232", "target": "species_425425" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066224", "target": "reaction_10066232" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066224", "target": "reaction_10066227" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4I7", "target": "species_10066224" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046067", "target": "A1A4I7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084767", "target": "species_10084765" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065958", "target": "reaction_10084767" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065958", "target": "reaction_10065965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH0", "target": "species_10065958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH0", "target": "species_10084765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTH0", "target": "species_10091540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001283", "target": "F1MTH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGK7", "target": "species_10065958" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGK7", "target": "species_10084765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGK7", "target": "species_10091540" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061078", "target": "F1MGK7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084763", "target": "reaction_10084767" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCB3", "target": "species_10084763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCB3", "target": "species_10084765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024268", "target": "F1MCB3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091583", "target": "species_188972" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10065970", "target": "reaction_10091583" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067569", "target": "species_10065970" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067569", "target": "A0A3Q1MCG6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066206", "target": "species_188972" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066203", "target": "reaction_10066206" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080053", "target": "species_10066203" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066270", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066270", "target": "species_83910" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066267", "target": "reaction_10066270" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027774", "target": "species_10066267" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066289", "target": "species_2889062" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066289", "target": "species_163953" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2889081", "target": "reaction_10066289" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8953505", "target": "species_2889081" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8953505", "target": "species_2889062" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_8953505", "target": "reaction_10088580" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066286", "target": "reaction_10066289" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085969", "target": "species_10066286" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066227", "target": "species_188972" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066034", "target": "species_74722" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066034", "target": "species_352022" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2731008", "target": "reaction_10066034" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066031", "target": "reaction_10066034" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N3A9", "target": "species_10066031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064202", "target": "G3N3A9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK15", "target": "species_10066031" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027587", "target": "E1BK15" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066004", "target": "species_74016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1606834", "target": "reaction_10066004" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066001", "target": "reaction_10066004" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ38", "target": "species_10066001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082890", "target": "A0A3Q1MQ38" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N2G9", "target": "species_10066001" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077727", "target": "A0A3Q1N2G9" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_2730676", "target": "reaction_10066004" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066199", "target": "species_188972" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066196", "target": "reaction_10066199" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLQ0", "target": "species_10066196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012099", "target": "E1BLQ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEP9", "target": "species_10066196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017615", "target": "E1BEP9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B792", "target": "species_10066196" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049019", "target": "E1B792" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091542", "target": "species_10065958" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091540", "target": "reaction_10091542" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066282", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066282", "target": "species_2892454" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066279", "target": "reaction_10066282" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035648", "target": "species_10066279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035648", "target": "species_10066274" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065965", "target": "species_83910" }, { "type": "inhibitor", "sub_type": "other", "source": "species_2672379", "target": "reaction_10065965" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_2672383", "target": "reaction_10065965" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10065963", "target": "reaction_10065965" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027364", "target": "species_10065963" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066021", "target": "species_83910" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066018", "target": "reaction_10066021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL71", "target": "species_10066018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082451", "target": "A0A3Q1LL71" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N0G4", "target": "species_10066018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065331", "target": "G3N0G4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJ95", "target": "species_10066018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020495", "target": "F1MJ95" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066277", "target": "species_429056" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066274", "target": "reaction_10066277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065991", "target": "species_188972" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065988", "target": "reaction_10065991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCG6", "target": "species_10065988" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNC2", "target": "species_10065988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071379", "target": "A0A3Q1LNC2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUE0", "target": "species_10065988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078140", "target": "A0A3Q1MUE0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049035", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049035", "target": "species_10049032" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049028", "target": "reaction_10049035" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091701", "target": "species_10091699" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049014", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049014", "target": "species_10049011" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049009", "target": "reaction_10049014" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048059", "target": "species_10048057" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048055", "target": "reaction_10048059" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048055", "target": "reaction_10049335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048055" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048057" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048063" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048332" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF6", "target": "species_10048340" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032332", "target": "F1MUF6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032332", "target": "species_10048053" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048049", "target": "reaction_10048059" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083796", "target": "species_10048049" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083796", "target": "A0A3Q1LN46" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LN46", "target": "species_10048057" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048045", "target": "species_10048043" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_140648", "target": "reaction_10048045" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048041", "target": "reaction_10048045" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIA5", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIA5", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084008", "target": "E1BIA5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ10", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BQ10", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015083", "target": "E1BQ10" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDQ6", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDQ6", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081011", "target": "A2VDQ6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW29", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW29", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020042", "target": "F1MW29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB78", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB78", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075672", "target": "A0A3Q1MB78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF53", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF53", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031089", "target": "E1BF53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DJ5", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DJ5", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031090", "target": "Q08DJ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM2", "target": "species_10048041" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZM2", "target": "species_10048043" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065042", "target": "G3MZM2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048348", "target": "species_10048346" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048344", "target": "reaction_10048348" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7P7", "target": "species_10048344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7P7", "target": "species_10048346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7P7", "target": "species_10048332" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070841", "target": "A0A3Q1M7P7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070841", "target": "species_10048330" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048065", "target": "species_10048063" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048061", "target": "reaction_10048065" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048334", "target": "species_10048332" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048053", "target": "reaction_10048334" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048053", "target": "reaction_10048352" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10048330", "target": "reaction_10048334" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048352", "target": "species_10048350" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042235", "target": "reaction_10048352" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070790", "target": "species_10042235" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070790", "target": "A0A3Q1MRJ9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MRJ9", "target": "species_10048350" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048342", "target": "species_10048340" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048338", "target": "reaction_10048342" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10048336", "target": "reaction_10048342" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049335", "target": "species_10048061" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044043", "target": "species_10044041" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044014", "target": "reaction_10044043" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044014", "target": "reaction_10049283" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044014", "target": "reaction_10044018" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044014", "target": "reaction_10044024" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044014", "target": "reaction_10044034" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049290", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049290", "target": "species_10040563" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049037", "target": "reaction_10049290" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049037", "target": "reaction_10049039" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049287", "target": "reaction_10049290" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049283", "target": "species_10049281" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044018", "target": "species_10044016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049364", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049364", "target": "species_10044014" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044026", "target": "reaction_10049364" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044026", "target": "reaction_10044030" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085323", "target": "species_29416" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085323", "target": "species_8869207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8869214", "target": "reaction_10085323" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10085320", "target": "reaction_10085323" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006727", "target": "species_10085320" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10048182", "target": "species_10037604" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037602", "target": "reaction_10048182" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072426", "target": "species_10072423" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072426", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072426", "target": "species_10072399" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072421", "target": "reaction_10072426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY8", "target": "species_10072421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHY8", "target": "species_10072423" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075339", "target": "A0A3Q1LHY8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6P5", "target": "species_10072421" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6P5", "target": "species_10072423" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067242", "target": "A0A3Q1M6P5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072399", "target": "reaction_10072401" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072401", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072401", "target": "species_10072322" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072322", "target": "reaction_10072326" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072326", "target": "species_10072324" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_5623403", "target": "reaction_10072326" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072475", "target": "species_10072467" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072451", "target": "reaction_10072475" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIM2", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIM2", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIM2", "target": "species_10072441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013306", "target": "Q0IIM2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU26", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU26", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU26", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU26", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032389", "target": "F1MU26" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032389", "target": "species_10072233" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ5", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ5", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ5", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BHJ5", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008587", "target": "E1BHJ5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008587", "target": "species_10072249" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ97", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ97", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ97", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1JQ97", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010013", "target": "Q1JQ97" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010013", "target": "species_10072237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4X0", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4X0", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4X0", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4X0", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042964", "target": "F1N4X0" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042964", "target": "species_10072253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF9", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF9", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF9", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF9", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014216", "target": "A6QLF9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014216", "target": "species_10072241" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W1", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W1", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W1", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N2W1", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064380", "target": "G3N2W1" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064380", "target": "species_10072257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN34", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN34", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN34", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN34", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026844", "target": "E1BN34" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026844", "target": "species_10072229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB52", "target": "species_10072451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB52", "target": "species_10072467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB52", "target": "species_10072473" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MB52", "target": "species_10072259" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006505", "target": "F1MB52" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006505", "target": "species_10072245" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10072473", "target": "reaction_10072475" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072435", "target": "species_10072259" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072245", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072229", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072257", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072241", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072253", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072237", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072249", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072233", "target": "reaction_10072435" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072259", "target": "reaction_10072453" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072453", "target": "species_10072451" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072449", "target": "reaction_10072453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072441", "target": "reaction_10072453" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057569", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057566", "target": "reaction_10057569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q4PJK1", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024576", "target": "Q4PJK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDT0", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019888", "target": "A2VDT0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7K3", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064709", "target": "E1B7K3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLD6", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022142", "target": "F1MLD6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTJ1", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009938", "target": "F1MTJ1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0E8", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010960", "target": "F1N0E8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1T8", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065475", "target": "G3N1T8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKB0", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020543", "target": "F1MKB0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9N0", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021458", "target": "E1B9N0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFH2", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086274", "target": "A0A3Q1MFH2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPE6", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074581", "target": "A0A3Q1MPE6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDC5", "target": "species_10057566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BDC5", "target": "species_10046640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039169", "target": "E1BDC5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML52", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022193", "target": "F1ML52" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJA9", "target": "species_10057566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJA9", "target": "species_10046640" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018162", "target": "F1MJA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BCM0", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004406", "target": "E1BCM0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MC54", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046307", "target": "F1MC54" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP51", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015122", "target": "F1MP51" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MPV7", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010214", "target": "F1MPV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKI8", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011681", "target": "E1BKI8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N553", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007132", "target": "F1N553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M6H7", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071160", "target": "A0A3Q1M6H7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV89", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028357", "target": "A4FV89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXZ4", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011219", "target": "F1MXZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BII8", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023770", "target": "E1BII8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B760", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025668", "target": "E1B760" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLH0", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005335", "target": "E1BLH0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDM5", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017003", "target": "F1MDM5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMA2", "target": "species_10057566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022102", "target": "E1BMA2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057365", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057362", "target": "reaction_10057365" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGY2", "target": "species_10057362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011376", "target": "E1BGY2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N467", "target": "species_10057362" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014706", "target": "F1N467" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057665", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057662", "target": "reaction_10057665" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW24", "target": "species_10057662" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020046", "target": "F1MW24" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057656", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057653", "target": "reaction_10057656" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1D1", "target": "species_10057653" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063834", "target": "G3N1D1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057682", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057679", "target": "reaction_10057682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q8HZT2", "target": "species_10057679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013646", "target": "Q8HZT2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEH1", "target": "species_10057679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000030656", "target": "E1BEH1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057616", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057613", "target": "reaction_10057616" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N1Q6", "target": "species_10057613" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065420", "target": "G3N1Q6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090498", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090498", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090498", "target": "species_9027049" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10090495", "target": "reaction_10090498" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084300", "target": "species_10084295" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084266", "target": "reaction_10084300" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071362", "target": "species_10084266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071362", "target": "species_10084295" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10084297", "target": "reaction_10084300" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10045642", "target": "reaction_10084300" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083113", "target": "species_8876730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083113", "target": "species_216762" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163579", "target": "reaction_10083113" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_163579", "target": "reaction_10086557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8876730", "target": "reaction_10071388" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_216762", "target": "reaction_10044666" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083110", "target": "reaction_10083113" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026745", "target": "species_10083110" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085994", "target": "species_10085992" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085990", "target": "reaction_10085994" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8848047", "target": "reaction_10085994" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085992", "target": "reaction_10086002" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086026", "target": "species_8876704" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086026", "target": "species_76194" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8876704", "target": "species_8866926" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8876704", "target": "species_10084422" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_8876704", "target": "species_10084692" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086023", "target": "reaction_10086026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033962", "target": "species_10086023" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086557", "target": "species_8876730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086557", "target": "species_216762" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086554", "target": "reaction_10086557" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056670", "target": "species_10086554" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086002", "target": "species_10085990" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086002", "target": "species_10086000" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085998", "target": "reaction_10086002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085568", "target": "species_10085998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085568", "target": "A0A3Q1LT67" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086000", "target": "reaction_10086004" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LT67", "target": "species_10086000" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086004", "target": "species_193384" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086004", "target": "species_10085998" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044020", "target": "species_10037455" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037447", "target": "reaction_10044020" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065426", "target": "species_10037447" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065426", "target": "G3MX19" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037453", "target": "reaction_10044020" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037455", "target": "reaction_10049300" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10037455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10037465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10037504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10037514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MX19", "target": "species_10050628" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049300", "target": "species_10037465" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037463", "target": "reaction_10049300" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040521", "target": "species_10040519" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040517", "target": "reaction_10040521" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033975", "target": "species_10040517" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033975", "target": "Q0P5A5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040513", "target": "reaction_10040521" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040519", "target": "reaction_10057816" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A5", "target": "species_10040519" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A5", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A5", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0P5A5", "target": "species_10057814" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040542", "target": "species_10040539" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040537", "target": "reaction_10040542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10040537" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10040539" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10056599" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10087392" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10087465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10087491" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10087501" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PKM2", "target": "species_10087390" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011001", "target": "A5PKM2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011001", "target": "species_10040572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011001", "target": "species_10040574" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10040576", "target": "species_10040574" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040572", "target": "reaction_10040576" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10040503", "target": "species_10040501" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033512", "target": "species_10033510" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033414", "target": "reaction_10033512" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10033508", "target": "reaction_10033512" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10033466", "target": "species_10033464" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10033462", "target": "reaction_10033466" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIF0", "target": "species_10033462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIF0", "target": "species_10033464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009882", "target": "E1BIF0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZN5", "target": "species_10033462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZN5", "target": "species_10033464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000316", "target": "Q3SZN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ14", "target": "species_10033462" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ14", "target": "species_10033464" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047798", "target": "A6QQ14" }, { "type": "reactant", "sub_type": "", "source": "species_68419", "target": "reaction_10033466" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087385", "target": "species_10087383" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087381", "target": "reaction_10087385" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087383", "target": "reaction_10087394" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056616", "target": "species_10056566" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056616", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056616", "target": "species_10056614" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056599", "target": "reaction_10056616" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10056599", "target": "reaction_10056602" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057816", "target": "species_10057814" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056564", "target": "reaction_10057816" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057814", "target": "reaction_10057821" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056602", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10056602", "target": "species_10056566" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10056602", "target": "species_10056564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057821", "target": "species_10040519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057821", "target": "species_10057818" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087487", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087487", "target": "species_10087465" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087392", "target": "reaction_10087487" }, { "type": "catalyst", "sub_type": "", "source": "species_10087484", "target": "reaction_10087487" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087503", "target": "species_10087501" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087491", "target": "reaction_10087503" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087394", "target": "species_10087392" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10087390", "target": "reaction_10087394" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065794", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065794", "target": "species_10065792" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065782", "target": "reaction_10065794" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3G4", "target": "species_10065782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3G4", "target": "species_10065792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019603", "target": "F1N3G4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH70", "target": "species_10065782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH70", "target": "species_10065792" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017174", "target": "F1MH70" }, { "type": "catalyst", "sub_type": "", "source": "species_2529006", "target": "reaction_10065794" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035745", "target": "species_10035743" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035737", "target": "reaction_10035745" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10035747", "target": "species_10035739" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035731", "target": "reaction_10035747" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074692", "target": "species_10074690" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074688", "target": "reaction_10074692" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074690", "target": "reaction_10074695" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R5E4", "target": "species_10074690" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074695", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074695", "target": "species_10033532" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051465", "target": "species_10051453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051445", "target": "reaction_10051465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMQ3", "target": "species_10051445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMQ3", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMQ3", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMQ3", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003380", "target": "E1BMQ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7N9", "target": "species_10051445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7N9", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7N9", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7N9", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022106", "target": "A5D7N9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAL2", "target": "species_10051445" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAL2", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAL2", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAL2", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014256", "target": "E1BAL2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051395", "target": "reaction_10051465" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M302", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M302", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M302", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M302", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M302", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068526", "target": "A0A3Q1M302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8WFK5", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8WFK5", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8WFK5", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8WFK5", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A8WFK5", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048435", "target": "A8WFK5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG9", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG9", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG9", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG9", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLG9", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061053", "target": "F1MLG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA18", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA18", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA18", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA18", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EA18", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009094", "target": "Q5EA18" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NKU0", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005369", "target": "Q2NKU0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW5", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW5", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW5", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW5", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DW5", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027600", "target": "Q08DW5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAK5", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAK5", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAK5", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAK5", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BAK5", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001748", "target": "E1BAK5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXW4", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXW4", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXW4", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXW4", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MXW4", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064627", "target": "G3MXW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBK8", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBK8", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBK8", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBK8", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBK8", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032953", "target": "Q3ZBK8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWP8", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWP8", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWP8", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWP8", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YWP8", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068875", "target": "A7YWP8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBR7", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017996", "target": "Q2TBR7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH6", "target": "species_10051395" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH6", "target": "species_10051453" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH6", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH6", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LTH6", "target": "species_10051459" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039939", "target": "A0A3Q1LTH6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051453", "target": "reaction_10051463" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051451", "target": "species_10051431" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051451", "target": "species_10051445" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051451", "target": "species_10051449" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051447", "target": "reaction_10051451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E613", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E613", "target": "species_10051449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E613", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E613", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049496", "target": "G5E613" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB33", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB33", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB33", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BB33", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042677", "target": "E1BB33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG8", "target": "species_10051447" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG8", "target": "species_10051431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG8", "target": "species_10051459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG8", "target": "species_10051457" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027964", "target": "A7MBG8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051335", "target": "reaction_10051451" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP30", "target": "species_10051335" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LP30", "target": "species_10051449" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083436", "target": "A0A3Q1LP30" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051461", "target": "species_10051447" }, { "type": "reactant", "sub_type": "", "source": "species_10035218", "target": "reaction_10051461" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051459", "target": "reaction_10051461" }, { "type": "reactant", "sub_type": "", "source": "species_10035105", "target": "reaction_10051461" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051463", "target": "species_10051459" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051457", "target": "reaction_10051463" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058792", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058792", "target": "species_113528" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057070", "target": "species_10057046" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057070", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057070", "target": "species_113528" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063560", "target": "species_10063558" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063560", "target": "species_10060342" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043501", "target": "reaction_10063560" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060344", "target": "reaction_10063560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M285", "target": "species_10060344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M285", "target": "species_10060342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M285", "target": "species_10060328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M285", "target": "species_10060330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M285", "target": "species_10060332" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072870", "target": "A0A3Q1M285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML06", "target": "species_10060344" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML06", "target": "species_10060342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML06", "target": "species_10060328" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML06", "target": "species_10060330" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML06", "target": "species_10060332" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018956", "target": "F1ML06" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063562", "target": "species_10060330" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060328", "target": "reaction_10063562" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060330", "target": "reaction_10063564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060346", "target": "species_10060344" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060332", "target": "reaction_10060346" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063564", "target": "species_10060332" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090604", "target": "species_10090599" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10090604", "target": "species_10090601" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090597", "target": "reaction_10090604" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052816", "target": "species_10090597" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052816", "target": "species_10090599" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052816", "target": "species_10090601" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037293", "target": "species_10037229" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037293", "target": "species_10037291" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037287", "target": "reaction_10037293" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD58", "target": "species_10037287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD58", "target": "species_10037229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD58", "target": "species_10044920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MD58", "target": "species_10037283" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008706", "target": "F1MD58" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL36", "target": "species_10037287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL36", "target": "species_10037291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL36", "target": "species_10037285" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005496", "target": "Q2NL36" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005496", "target": "species_10037260" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005496", "target": "species_10037262" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10043021" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10043059" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10044906" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10090573" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10043039" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037229", "target": "reaction_10091188" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090504", "target": "species_9027547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090506", "target": "species_9027614" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090508", "target": "species_9027622" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090510", "target": "species_9028280" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075037", "target": "species_427497" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075037", "target": "species_427498" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075037", "target": "species_10074778" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075030", "target": "reaction_10075037" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075034", "target": "reaction_10075037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026521", "target": "species_10075034" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074798", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074798", "target": "species_10074789" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074795", "target": "reaction_10074798" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076339", "target": "species_30555" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076339", "target": "species_10075051" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076336", "target": "reaction_10076339" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060476", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060476", "target": "species_1806234" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060456", "target": "reaction_10060476" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047316", "target": "species_10060456" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047316", "target": "F1MK34" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083369", "target": "species_6814794" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083369", "target": "species_6814795" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2239407", "target": "reaction_10083369" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083366", "target": "reaction_10083369" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015375", "target": "species_10083366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083211", "target": "species_1498750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083211", "target": "species_1524021" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083208", "target": "reaction_10083211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084401", "target": "species_10083208" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10082931", "target": "species_10082929" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082927", "target": "reaction_10082931" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003561", "target": "species_10082927" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003561", "target": "species_10082929" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10082929", "target": "reaction_10082934" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083092", "target": "species_113582" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083092", "target": "species_6810412" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6810408", "target": "reaction_10083092" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6810408", "target": "reaction_10082923" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_6810408", "target": "reaction_10083077" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083089", "target": "reaction_10083092" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082934", "target": "species_6810408" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082934", "target": "species_113550" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060569", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060569", "target": "species_202247" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060566", "target": "reaction_10060569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDQ5", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDQ5", "target": "species_10060547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003878", "target": "F1MDQ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D1", "target": "species_10060566" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8D1", "target": "species_10060495" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043102", "target": "E1B8D1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBU9", "target": "species_10060566" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017388", "target": "F1MBU9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060473", "target": "species_1806240" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060473", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060470", "target": "reaction_10060473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060470", "target": "reaction_10060572" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082136", "target": "species_10082134" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082132", "target": "reaction_10082136" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082132", "target": "reaction_10082147" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004852", "target": "species_10082132" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004852", "target": "A7MB43" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10082128", "target": "reaction_10082136" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050192", "target": "species_10082128" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050192", "target": "F1ME94" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME94", "target": "species_10082134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ME94", "target": "species_10082149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB43", "target": "species_10082134" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB43", "target": "species_10082149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB43", "target": "species_10082145" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060600", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060600", "target": "species_1806240" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806224", "target": "reaction_10060600" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806224", "target": "reaction_10082152" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060532", "target": "reaction_10060600" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060532", "target": "reaction_10060535" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYK5", "target": "species_10060532" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYK5", "target": "species_10082149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYK5", "target": "species_10082145" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069408", "target": "A0A3Q1LYK5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069408", "target": "species_10060526" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085784", "target": "species_10085782" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085767", "target": "reaction_10085784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000317", "target": "species_10085767" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000317", "target": "F6R352" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000317", "target": "species_10085777" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000317", "target": "species_10085773" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806200", "target": "reaction_10085784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806200", "target": "reaction_10060574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R352", "target": "species_10085782" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060572", "target": "species_1806224" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060572", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806276", "target": "reaction_10060572" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806276", "target": "reaction_10060535" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806276", "target": "reaction_10082155" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806276", "target": "reaction_10085697" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806276", "target": "reaction_10060579" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060595", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060595", "target": "species_392417" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060592", "target": "reaction_10060595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNM5", "target": "species_10060592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNM5", "target": "species_10060511" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015257", "target": "A6QNM5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB5", "target": "species_10060592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB5", "target": "species_10060511" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB5", "target": "species_10061081" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022635", "target": "E1BLB5" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022635", "target": "species_10060509" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085780", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10085780", "target": "species_10085773" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085777", "target": "reaction_10085780" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085773", "target": "reaction_10085775" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044855", "target": "reaction_10085780" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000488", "target": "species_10044855" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060535", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060535", "target": "species_426658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082152", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082152", "target": "species_1806240" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082149", "target": "reaction_10082152" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10082149", "target": "reaction_10082155" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082155", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082155", "target": "species_426658" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060429", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060429", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060461", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060461", "target": "species_392417" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060458", "target": "reaction_10060461" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060458", "target": "reaction_10060518" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060458", "target": "reaction_10060597" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MK34", "target": "species_10060458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLN5", "target": "species_10060458" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002604", "target": "A6QLN5" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10085775", "target": "species_10085767" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060590", "target": "species_1806276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060590", "target": "species_29372" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060585", "target": "reaction_10060590" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060585", "target": "reaction_10060588" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060585", "target": "reaction_10061014" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060585", "target": "reaction_10061046" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079052", "target": "species_10060585" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085697", "target": "species_10085695" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085693", "target": "reaction_10085697" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7V8", "target": "species_10085693" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7V8", "target": "species_10085695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061135", "target": "E1B7V8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060579", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060579", "target": "species_202247" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060576", "target": "reaction_10060579" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082147", "target": "species_10082145" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10060526", "target": "reaction_10082147" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060514", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060514", "target": "species_202247" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060511", "target": "reaction_10060514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060550", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060550", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060547", "target": "reaction_10060550" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083800", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083800", "target": "species_8849958" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8849959", "target": "reaction_10083800" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806205", "target": "species_8849958" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806205", "target": "reaction_10060558" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806259", "target": "species_8849958" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1806259", "target": "species_10082921" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083797", "target": "reaction_10083800" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029059", "target": "species_10083797" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060588", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060588", "target": "species_1806200" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060558", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060558", "target": "species_1806259" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060574", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060574", "target": "species_1806199" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806199", "target": "reaction_10060501" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806199", "target": "reaction_10060518" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060501", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060501", "target": "species_1806200" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060518", "target": "species_1806180" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060518", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060614", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060614", "target": "species_1806238" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060611", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060611", "target": "species_1806217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806230", "target": "reaction_10060611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806217", "target": "reaction_10060498" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806217", "target": "reaction_10085316" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060608", "target": "reaction_10060611" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MHQ7", "target": "species_10060608" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081928", "target": "A0A3Q1MHQ7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060483", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060483", "target": "species_1806217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1806165", "target": "reaction_10060483" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060480", "target": "reaction_10060483" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001784", "target": "species_10060480" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060498", "target": "species_1806230" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060498", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060495", "target": "reaction_10060498" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060597", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060597", "target": "species_1806217" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524146", "target": "reaction_10060597" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1524146", "target": "reaction_10060516" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060516", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060516", "target": "species_1806159" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085843", "target": "species_8874460" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8874484", "target": "reaction_10085843" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085840", "target": "reaction_10085843" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LVF0", "target": "species_10085840" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072298", "target": "A0A3Q1LVF0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040152", "target": "species_176501" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040152", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176575", "target": "reaction_10040152" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158466", "target": "reaction_10040129" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040149", "target": "reaction_10040152" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC30", "target": "species_10040149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC30", "target": "species_10040109" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC30", "target": "species_10040075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC30", "target": "species_10040095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC30", "target": "species_10040133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015862", "target": "Q3ZC30" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG19", "target": "species_10040149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG19", "target": "species_10040087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG19", "target": "species_10040095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BG19", "target": "species_10040133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000031917", "target": "E1BG19" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S6", "target": "species_10040149" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S6", "target": "species_10040087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S6", "target": "species_10040095" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0S6", "target": "species_10040133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028234", "target": "F1N0S6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040120", "target": "species_176555" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040120", "target": "species_158466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040087", "target": "reaction_10040120" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040087", "target": "reaction_10040122" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040122", "target": "species_176483" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040122", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176565", "target": "reaction_10040122" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040157", "target": "species_176500" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040157", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176566", "target": "reaction_10040157" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040154", "target": "reaction_10040157" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP36", "target": "species_10040154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MP36", "target": "species_10040144" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072780", "target": "A0A3Q1MP36" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP4", "target": "species_10040154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBP4", "target": "species_10040095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003629", "target": "F1MBP4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P50227", "target": "species_10040154" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P50227", "target": "species_10038228" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P50227", "target": "species_10040144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P50227", "target": "species_10040095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011388", "target": "P50227" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076799", "target": "species_5695950" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076799", "target": "species_76179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5695960", "target": "reaction_10076799" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5695950", "target": "reaction_10040147" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076796", "target": "reaction_10076799" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024782", "target": "species_10076796" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038320", "target": "species_158859" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038320", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158847", "target": "reaction_10038320" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038228", "target": "reaction_10038320" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038228", "target": "reaction_10038231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038228", "target": "reaction_10038318" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038228", "target": "reaction_10038340" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040112", "target": "species_176665" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040112", "target": "species_158466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040109", "target": "reaction_10040112" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4N6", "target": "species_10040109" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4N6", "target": "species_10040133" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4N6", "target": "species_10040104" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063187", "target": "A1A4N6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040147", "target": "species_176600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040147", "target": "species_158466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040144", "target": "reaction_10040147" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040115", "target": "species_176492" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040115", "target": "species_158466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040075", "target": "reaction_10040115" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040117", "target": "species_176564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040117", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176667", "target": "reaction_10040117" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040095", "target": "reaction_10040117" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040095", "target": "reaction_10040098" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZX9", "target": "species_10040095" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011474", "target": "F1MZX9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038231", "target": "species_158472" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038231", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158469", "target": "reaction_10038231" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088617", "target": "species_742343" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088617", "target": "species_10088610" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088606", "target": "reaction_10088617" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043559", "target": "species_10088606" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043559", "target": "species_10088610" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040136", "target": "species_176496" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040136", "target": "species_158466" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040133", "target": "reaction_10040136" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040107", "target": "species_176502" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040107", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176617", "target": "reaction_10040107" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176617", "target": "reaction_10041097" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040104", "target": "reaction_10040107" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040104", "target": "reaction_10040131" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038318", "target": "species_158466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038318", "target": "species_158850" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158858", "target": "reaction_10038318" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040129", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040129", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10040126", "target": "reaction_10040129" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005311", "target": "species_10040126" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040131", "target": "species_176618" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040131", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176478", "target": "reaction_10040131" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040098", "target": "species_176519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040098", "target": "species_158466" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_176486", "target": "reaction_10040098" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038340", "target": "species_159352" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038340", "target": "species_158466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088580", "target": "species_8851226" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088580", "target": "species_8953493" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088577", "target": "reaction_10088580" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIR7", "target": "species_10088577" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020766", "target": "A0A452DIR7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050342", "target": "species_10050340" }, { "type": "reactant", "sub_type": "", "source": "species_450444", "target": "reaction_10050342" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050336", "target": "reaction_10050342" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8I4", "target": "species_10050336" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8I4", "target": "species_10050340" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075547", "target": "A0A3Q1M8I4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10082923", "target": "species_10082921" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069400", "target": "reaction_10082923" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069400", "target": "reaction_10083072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066213", "target": "species_10069400" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066213", "target": "G3MY31" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY31", "target": "species_10082921" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY31", "target": "species_10083070" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MY31", "target": "species_10083074" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086155", "target": "species_10086153" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086151", "target": "reaction_10086155" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083072", "target": "species_10083070" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083070", "target": "reaction_10083077" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083077", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083077", "target": "species_10083074" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090593", "target": "species_10090591" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090579", "target": "reaction_10090593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022338", "target": "species_10090579" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022338", "target": "Q08DL6" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090589", "target": "reaction_10090593" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBU3", "target": "species_10090589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NBU3", "target": "species_10090591" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081070", "target": "A0A3Q1NBU3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DL6", "target": "species_10090591" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090770", "target": "species_10090768" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10090766", "target": "reaction_10090770" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUD4", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUD4", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026285", "target": "A4FUD4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S5", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1S5", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047447", "target": "A0A3Q1M1S5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTZ2", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTZ2", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074727", "target": "A0A3Q1MTZ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148K5", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148K5", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011022", "target": "Q148K5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ7", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MSZ7", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082884", "target": "A0A3Q1MSZ7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQZ0", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQZ0", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016739", "target": "A6QQZ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI69", "target": "species_10090766" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI69", "target": "species_10090768" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009885", "target": "A0A452DI69" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10090732", "target": "reaction_10090770" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009921", "target": "species_10090732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009921", "target": "Q3SZD1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZD1", "target": "species_10090768" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039049", "target": "species_10039039" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039039", "target": "reaction_10039044" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039044", "target": "species_10039041" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039044", "target": "species_113521" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039041", "target": "reaction_10039047" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039047", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039047", "target": "species_113593" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039047", "target": "species_10039037" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035417", "target": "species_29374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035417", "target": "species_73871" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035417", "target": "species_113559" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035374", "target": "species_113526" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035374", "target": "species_73911" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035374", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035374", "target": "species_73909" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035374", "target": "species_29362" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73911", "target": "reaction_10035374" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_73911", "target": "reaction_10035363" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_73909", "target": "reaction_10035374" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73909", "target": "reaction_10035415" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73909", "target": "reaction_10035363" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035360", "target": "reaction_10035374" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035360", "target": "reaction_10035363" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q02337", "target": "species_10035360" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082799", "target": "Q02337" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035415", "target": "species_73871" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035415", "target": "species_113536" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035412", "target": "reaction_10035415" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LIX4", "target": "species_10035412" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077723", "target": "A0A3Q1LIX4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065944", "target": "species_10065942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065944", "target": "species_2466098" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035617", "target": "reaction_10065944" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035617", "target": "reaction_10035619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN7", "target": "species_10035617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAN7", "target": "species_10065942" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077886", "target": "A0A3Q1MAN7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035596", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035596", "target": "species_30991" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035583", "target": "reaction_10035596" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011564", "target": "species_10035583" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035592", "target": "reaction_10035596" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087322", "target": "species_10035592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087322", "target": "P46065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087322", "target": "species_10035588" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035594", "target": "reaction_10035596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46065", "target": "species_10035594" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P46065", "target": "species_10035590" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035590", "target": "reaction_10035596" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10065808", "target": "species_10065799" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065808", "target": "species_76194" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10065796", "target": "reaction_10065808" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2534019", "target": "reaction_10065808" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065805", "target": "reaction_10065808" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9N181", "target": "species_10065805" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050460", "target": "Q9N181" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZK0", "target": "species_10065805" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035619", "target": "species_29372" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10035619", "target": "species_2565923" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035601", "target": "reaction_10035619" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035607", "target": "reaction_10035619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBQ1", "target": "species_10035607" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068795", "target": "F1MBQ1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065940", "target": "species_10035590" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035588", "target": "reaction_10065940" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078600", "target": "species_10078598" }, { "type": "reactant", "sub_type": "", "source": "species_10078596", "target": "reaction_10078600" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078418", "target": "reaction_10078600" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078418", "target": "reaction_10078446" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MMZ4", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061495", "target": "F1MMZ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078418" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N119", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026956", "target": "F1N119" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078488", "target": "species_10078486" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078484", "target": "reaction_10078488" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWK1", "target": "species_10078484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWK1", "target": "species_10078486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWK1", "target": "species_10078520" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075847", "target": "A0A3Q1LWK1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7S3", "target": "species_10078484" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7S3", "target": "species_10078486" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7S3", "target": "species_10078520" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061281", "target": "E1B7S3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078486", "target": "reaction_10078522" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078522", "target": "species_10078520" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078444", "target": "reaction_10078522" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4B1", "target": "species_10078444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4B1", "target": "species_10078520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4B1", "target": "species_10078442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4B1", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6Q4B1", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045228", "target": "F6Q4B1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7N7", "target": "species_10078444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7N7", "target": "species_10078520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7N7", "target": "species_10078442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7N7", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7N7", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000040145", "target": "G3X7N7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N104", "target": "species_10078444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N104", "target": "species_10078520" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N104", "target": "species_10078442" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N104", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N104", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026987", "target": "F1N104" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078446", "target": "species_10078444" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078442", "target": "reaction_10078446" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078464", "target": "species_10078462" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078458", "target": "reaction_10078464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHC4", "target": "species_10078458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHC4", "target": "species_10078456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LHC4", "target": "species_10078462" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083397", "target": "A0A3Q1LHC4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW19", "target": "species_10078458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW19", "target": "species_10078456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MW19", "target": "species_10078462" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001076", "target": "F1MW19" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078456", "target": "reaction_10078464" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078456", "target": "reaction_10078466" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078466", "target": "species_10078458" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10045110", "target": "reaction_10078466" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078518", "target": "species_10078516" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078514", "target": "reaction_10078518" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV08", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV08", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084157", "target": "A0A3Q1MV08" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ2", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBJ2", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006420", "target": "E1BBJ2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW9", "target": "species_10078514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRW9", "target": "species_10078516" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068330", "target": "A0A3Q1LRW9" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043423", "target": "reaction_10078518" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046648", "target": "species_10046646" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046648", "target": "species_29420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046644", "target": "reaction_10046648" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044632", "target": "reaction_10046648" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044632", "target": "reaction_10044634" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044626", "target": "reaction_10046648" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044626", "target": "reaction_10044634" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046623", "target": "species_10044626" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044624", "target": "reaction_10046623" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046642", "target": "species_10046640" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10046640", "target": "reaction_10046642" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046630", "target": "species_10044632" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044630", "target": "reaction_10046630" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043885", "target": "species_10043883" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209767", "target": "reaction_10043885" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043881", "target": "reaction_10043885" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043881", "target": "reaction_10043984" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075079", "target": "species_10043881" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075079", "target": "A0A3Q1LQ02" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043883", "target": "reaction_10088926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ02", "target": "species_10043883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ02", "target": "species_10043895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ02", "target": "species_10043901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ02", "target": "species_10043982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQ02", "target": "species_10044732" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043903", "target": "species_10043901" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043895", "target": "reaction_10043903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKV7", "target": "species_10043895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKV7", "target": "species_10043901" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKV7", "target": "species_10044728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKV7", "target": "species_10044732" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039417", "target": "F1MKV7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039417", "target": "species_10043899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000039417", "target": "species_10044730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088926", "target": "species_209767" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088926", "target": "species_10043881" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043984", "target": "species_10043982" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_209906", "target": "reaction_10043984" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043982", "target": "reaction_10044741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088928", "target": "species_350136" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088928", "target": "species_10043899" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044728", "target": "reaction_10088928" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044739", "target": "species_10043895" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044732", "target": "reaction_10044739" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044736", "target": "reaction_10044739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005988", "target": "species_10044736" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044741", "target": "species_10044732" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044730", "target": "reaction_10044741" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043910", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043910", "target": "species_350159" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10043910", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040922", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040922", "target": "species_191269" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040922", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191265", "target": "reaction_10040922" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191265", "target": "reaction_10088019" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191269", "target": "reaction_10040881" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040919", "target": "reaction_10040922" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040919", "target": "reaction_10040924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q6IE76", "target": "species_10040919" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016504", "target": "Q6IE76" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041664", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041664", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041664", "target": "species_195655" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_195691", "target": "reaction_10041664" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041661", "target": "reaction_10041664" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041661", "target": "reaction_10081988" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072112", "target": "species_10041661" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041728", "target": "species_193384" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041728", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_196420", "target": "reaction_10041728" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041725", "target": "reaction_10041728" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041725", "target": "reaction_10081990" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080856", "target": "species_10041725" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041671", "target": "species_195691" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194691", "target": "reaction_10041671" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194691", "target": "reaction_10081990" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041668", "target": "reaction_10041671" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041668", "target": "reaction_10081986" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012234", "target": "species_10041668" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040892", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040892", "target": "species_191385" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191409", "target": "reaction_10040892" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191385", "target": "reaction_10040924" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040889", "target": "reaction_10040892" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040889", "target": "reaction_10040895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56966", "target": "species_10040889" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017376", "target": "P56966" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040924", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040924", "target": "species_191265" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040895", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040895", "target": "species_191409" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191324", "target": "reaction_10040895" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041502", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041502", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041502", "target": "species_194661" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041502", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194657", "target": "reaction_10041502" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041481", "target": "reaction_10041502" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041481", "target": "reaction_10041484" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012167", "target": "species_10041481" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040913", "target": "species_191324" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040910", "target": "reaction_10040913" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A140T853", "target": "species_10040910" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005323", "target": "A0A140T853" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040881", "target": "species_191309" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040881", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040881", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040878", "target": "reaction_10040881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D9A8", "target": "species_10040878" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007228", "target": "A5D9A8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088019", "target": "species_8952135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088019", "target": "species_29372" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088016", "target": "reaction_10088019" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014674", "target": "species_10088016" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041493", "target": "species_194668" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041493", "target": "species_194704" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194681", "target": "reaction_10041493" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194725", "target": "reaction_10041493" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194688", "target": "reaction_10041493" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041490", "target": "reaction_10041493" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083496", "target": "species_191293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083496", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083496", "target": "species_76194" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083493", "target": "reaction_10083496" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MLP4", "target": "species_10083493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012548", "target": "A0A3Q1MLP4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040904", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040904", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040904", "target": "species_191424" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191374", "target": "reaction_10040904" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040901", "target": "reaction_10040904" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7Z064", "target": "species_10040901" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010315", "target": "A7Z064" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041484", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041484", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041484", "target": "species_194667" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041484", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194735", "target": "reaction_10041484" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041486", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041486", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041486", "target": "species_194657" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194723", "target": "reaction_10041486" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041474", "target": "reaction_10041486" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041474", "target": "reaction_10041477" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003991", "target": "species_10041474" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081986", "target": "species_6807054" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6807048", "target": "reaction_10081986" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6807054", "target": "reaction_10081988" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081988", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081988", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081988", "target": "species_6807057" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081990", "target": "species_6807048" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081990", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041477", "target": "species_194735" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041477", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041477", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038347", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038347", "target": "species_29356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038347", "target": "species_194073" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038347", "target": "species_76577" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_194096", "target": "reaction_10038347" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_192356", "target": "species_194073" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192356", "target": "reaction_10041308" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28701", "target": "species_194073" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041437", "target": "species_10041430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041437", "target": "species_83910" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041428", "target": "reaction_10041437" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014054", "target": "species_10041428" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014054", "target": "A0A452DID8" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_192483", "target": "reaction_10041437" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17687", "target": "species_192483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17687", "target": "species_10041430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28865", "target": "species_192483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28865", "target": "species_10041430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36274", "target": "species_192483" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36274", "target": "species_10041430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:9407", "target": "species_192483" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DID8", "target": "species_10041430" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DID8", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DID8", "target": "species_10071386" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16525", "target": "species_10041430" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041434", "target": "reaction_10041437" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021363", "target": "species_10041434" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085806", "target": "species_10085804" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10085802", "target": "reaction_10085806" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014559", "target": "species_10085802" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014559", "target": "A1A4M6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4M6", "target": "species_10085804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085291", "target": "species_8868400" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8868399", "target": "reaction_10085291" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8868399", "target": "reaction_10085316" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10085288", "target": "reaction_10085291" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYV2", "target": "species_10085288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083446", "target": "A0A3Q1LYV2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBD8", "target": "species_10085288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017982", "target": "E1BBD8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BL67", "target": "species_10085288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044841", "target": "E1BL67" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0E7", "target": "species_10085288" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066543", "target": "A0A3Q1M0E7" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066543", "target": "A0A3Q1MW81" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MW81", "target": "species_10085288" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041097", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041097", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041097", "target": "species_192194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192194", "target": "reaction_10041371" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041369", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041369", "target": "species_193843" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193829", "target": "reaction_10041369" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041371", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041371", "target": "species_193835" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041371", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193835", "target": "reaction_10041375" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041373", "target": "species_193829" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041373", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9617026", "target": "reaction_10041373" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041375", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041375", "target": "species_193830" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193830", "target": "reaction_10041377" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041377", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041377", "target": "species_193842" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041208", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041208", "target": "species_192096" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041208", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192013", "target": "reaction_10041208" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192013", "target": "reaction_10041317" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041179", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041179", "target": "species_192161" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041179", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191968", "target": "reaction_10041179" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041210", "target": "species_192030" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041210", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191980", "target": "reaction_10041210" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041308", "target": "species_193451" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041308", "target": "species_193514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041310", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041310", "target": "species_193387" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041310", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193436", "target": "reaction_10041310" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193387", "target": "reaction_10041327" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041104", "target": "species_192201" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041104", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041104", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192078", "target": "reaction_10041104" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192201", "target": "reaction_10041172" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041170", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041170", "target": "species_192087" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192064", "target": "reaction_10041170" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041301", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041301", "target": "species_193459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193442", "target": "reaction_10041301" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041223", "target": "reaction_10041301" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10041223", "target": "reaction_10041226" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041204", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041204", "target": "species_192136" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041204", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192136", "target": "reaction_10041111" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041172", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041172", "target": "species_191968" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041172", "target": "species_113600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041111", "target": "species_191980" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041111", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041321", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041321", "target": "species_193457" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041321", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193505", "target": "reaction_10041321" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193505", "target": "reaction_10041319" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041323", "target": "species_193442" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193429", "target": "reaction_10041323" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041226", "target": "species_113575" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041226", "target": "species_192342" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192316", "target": "reaction_10041226" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041197", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041197", "target": "species_192064" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192195", "target": "reaction_10041197" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041325", "target": "species_113563" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041325", "target": "species_193440" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041325", "target": "species_113521" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_193435", "target": "reaction_10041325" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041327", "target": "species_193435" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041327", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041327", "target": "species_113600" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041186", "target": "species_192316" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192308", "target": "reaction_10041186" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041317", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041317", "target": "species_192096" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041317", "target": "species_76577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041319", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041319", "target": "species_193457" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041319", "target": "species_76577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085316", "target": "species_8868393" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10085316", "target": "species_1806234" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076009", "target": "species_10076007" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069573", "target": "reaction_10076009" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080567", "target": "species_10069573" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080567", "target": "A0A3Q1LPC8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069565", "target": "reaction_10076009" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010319", "target": "species_10069565" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010319", "target": "Q2TBN3" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076007", "target": "reaction_10076071" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN3", "target": "species_10076007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN3", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN3", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN3", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN3", "target": "species_10077106" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPC8", "target": "species_10076007" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPC8", "target": "species_10076069" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPC8", "target": "species_10077087" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPC8", "target": "species_10077089" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LPC8", "target": "species_10077106" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077396", "target": "species_10077087" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076069", "target": "reaction_10077396" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077108", "target": "species_427497" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077108", "target": "species_10077106" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077089", "target": "reaction_10077108" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076071", "target": "species_10076069" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076071", "target": "species_10076065" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076067", "target": "reaction_10076071" }, { "type": "reactant", "sub_type": "", "source": "species_5688114", "target": "reaction_10076071" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077016", "target": "species_10036828" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10077016", "target": "species_10036653" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077009", "target": "reaction_10077016" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ75", "target": "species_10077009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ75", "target": "species_10036659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ75", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023078", "target": "Q1LZ75" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023078", "target": "species_10036653" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036653", "target": "reaction_10036661" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077013", "target": "reaction_10077016" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067380", "target": "species_10077013" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036661", "target": "species_10036659" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036657", "target": "reaction_10036661" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046336", "target": "species_10036657" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046336", "target": "E1BKV9" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036659", "target": "reaction_10077625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKV9", "target": "species_10036659" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKV9", "target": "species_10077623" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037517", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037517", "target": "species_10037514" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037504", "target": "reaction_10037517" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02453", "target": "species_10037504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02453", "target": "species_10037514" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02453", "target": "species_10037586" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P02453", "target": "species_10050628" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017420", "target": "P02453" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037514", "target": "reaction_10037588" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049071", "target": "species_10037554" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049069", "target": "reaction_10049071" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10037554", "target": "reaction_10037557" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049395", "target": "species_179838" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049395", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049426", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049426", "target": "species_10049420" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049418", "target": "reaction_10049426" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049423", "target": "reaction_10049426" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037557", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037557", "target": "species_114519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037588", "target": "species_10037586" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050630", "target": "species_10050626" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050630", "target": "species_10037514" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050628", "target": "reaction_10050630" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047475", "target": "species_29420" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047475", "target": "species_10047472" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10047470", "target": "reaction_10047475" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049039", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10049039", "target": "species_10040563" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10047985", "target": "species_10047983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037201", "target": "species_10037199" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037197", "target": "reaction_10037201" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037193", "target": "reaction_10037201" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037185", "target": "species_10037183" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037181", "target": "reaction_10037185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027214", "target": "species_10037181" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027214", "target": "E1BNP8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037177", "target": "reaction_10037185" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073946", "target": "species_10037177" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073946", "target": "A6QQT5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQT5", "target": "species_10037183" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNP8", "target": "species_10037183" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037187", "target": "species_10037110" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037108", "target": "reaction_10037187" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N172", "target": "species_10037108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N172", "target": "species_10037110" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N172", "target": "species_10078472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063128", "target": "G3N172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063128", "target": "species_10037102" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA24", "target": "species_10037108" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MA24", "target": "species_10037110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074231", "target": "A0A3Q1MA24" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037098", "target": "reaction_10037187" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006162", "target": "species_10037098" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006162", "target": "Q5EAB2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAB2", "target": "species_10037110" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037189", "target": "species_10037137" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037135", "target": "reaction_10037189" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037130", "target": "reaction_10037189" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037207", "target": "species_10037173" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081897", "target": "species_10081895" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081893", "target": "reaction_10081897" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086118", "target": "species_10081893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086118", "target": "species_10081895" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086118", "target": "A0A3Q1MXU1" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037264", "target": "species_10037262" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037260", "target": "reaction_10037264" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037262", "target": "reaction_10091186" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091186", "target": "species_10037285" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037285", "target": "reaction_10037289" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037285", "target": "reaction_10091191" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037285", "target": "reaction_10091188" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049241", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049243", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049262", "target": "species_109276" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049259", "target": "reaction_10049262" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77750", "target": "species_10049259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O77750", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082069", "target": "O77750" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049253", "target": "species_29356" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049250", "target": "reaction_10049253" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79099", "target": "species_10049250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P79099", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011024", "target": "P79099" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049271", "target": "species_192438" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_192438", "target": "reaction_10051141" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10049268", "target": "reaction_10049271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R5", "target": "species_10049268" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R5", "target": "species_10051138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3R5", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026782", "target": "F1N3R5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051145", "target": "species_192438" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051138", "target": "reaction_10051145" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051138", "target": "reaction_10051141" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNJ1", "target": "species_10051138" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNJ1", "target": "species_10051119" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MNJ1", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006790", "target": "F1MNJ1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051148", "target": "species_432019" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051119", "target": "reaction_10051148" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051119", "target": "reaction_10051150" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051150", "target": "species_29514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051136", "target": "species_29356" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051133", "target": "reaction_10051136" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051133", "target": "reaction_10051143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPM1", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026884", "target": "A0A3S5ZPM1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P06624", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013360", "target": "P06624" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWN9", "target": "species_10051133" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085930", "target": "A0A3Q1LWN9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051141", "target": "species_76116" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051143", "target": "species_109276" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041050", "target": "species_10041031" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041043", "target": "reaction_10041050" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK3", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK3", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BEK3", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027878", "target": "E1BEK3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHW8", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHW8", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHW8", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020624", "target": "Q2KHW8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW7", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW7", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRW7", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024914", "target": "F1MRW7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA0", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA0", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QA0", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014112", "target": "Q17QA0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAW0", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAW0", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MAW0", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017819", "target": "F1MAW0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18870", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18870", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18870", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007547", "target": "O18870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJG3", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJG3", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJG3", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016037", "target": "E1BJG3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ79", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ79", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1LZ79", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013582", "target": "Q1LZ79" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC10", "target": "species_10041043" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC10", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC10", "target": "species_10041037" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010912", "target": "Q3ZC10" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2274", "target": "species_10041043" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10041031", "target": "reaction_10041039" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:1604", "target": "species_10041031" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:1604", "target": "species_10041037" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10041047", "target": "reaction_10041050" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10041039", "target": "species_10041037" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10041035", "target": "reaction_10041039" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076267", "target": "species_10041035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076267", "target": "Q2TBK8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBK8", "target": "species_10041037" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039916", "target": "species_158602" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039916", "target": "species_174918" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_174932", "target": "reaction_10039916" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159154", "target": "species_174932" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159154", "target": "reaction_10044524" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17688", "target": "species_174932" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63860", "target": "species_174918" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32663", "target": "species_174918" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038333", "target": "reaction_10039916" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038333", "target": "reaction_10038336" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038333", "target": "reaction_10038338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076879", "target": "species_10038333" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076785", "target": "species_5694569" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076785", "target": "species_5694565" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5694574", "target": "reaction_10076785" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076782", "target": "reaction_10076785" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006038", "target": "species_10076782" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038336", "target": "species_159149" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038336", "target": "species_158602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159160", "target": "reaction_10038336" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038338", "target": "species_159160" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038338", "target": "species_158602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039749", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039749", "target": "species_158601" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039749", "target": "species_73473" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039746", "target": "reaction_10039749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P12378", "target": "species_10039746" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019302", "target": "P12378" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040682", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040682", "target": "species_189466" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040682", "target": "species_29376" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040679", "target": "reaction_10040682" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI36", "target": "species_10040679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005380", "target": "A0A452DI36" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_189444", "target": "reaction_10040682" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189444", "target": "reaction_10066416" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189444", "target": "reaction_10046698" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040654", "target": "species_189481" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040654", "target": "species_189480" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040654", "target": "species_189478" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189411", "target": "reaction_10040654" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189478", "target": "reaction_10040663" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040651", "target": "reaction_10040654" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKY9", "target": "species_10040651" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005398", "target": "E1BKY9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040688", "target": "species_10040686" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040688", "target": "species_29426" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_190173", "target": "reaction_10040688" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_190173", "target": "species_10040686" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10040669", "target": "reaction_10040688" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040669", "target": "reaction_10040672" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040672", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040672", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040672", "target": "species_189464" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189489", "target": "reaction_10040672" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189464", "target": "reaction_10040645" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066416", "target": "species_2995328" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10066416", "target": "species_159450" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2162257", "target": "reaction_10066416" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066413", "target": "reaction_10066416" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020336", "target": "species_10066413" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040645", "target": "species_189449" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040645", "target": "species_31633" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040642", "target": "reaction_10040645" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:36319", "target": "species_10040642" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIN5", "target": "species_10040642" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007052", "target": "Q2KIN5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040663", "target": "species_189481" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040663", "target": "species_189463" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040660", "target": "reaction_10040663" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56602", "target": "species_10040660" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061124", "target": "P56602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038380", "target": "species_159448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038380", "target": "species_159450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038380", "target": "species_159557" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159559", "target": "reaction_10038380" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_159557", "target": "reaction_10038382" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038377", "target": "reaction_10038380" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBE6", "target": "species_10038377" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038382", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038382", "target": "species_159572" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083864", "target": "species_109277" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083864", "target": "species_8870962" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8870906", "target": "reaction_10083864" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083858", "target": "reaction_10083864" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083858", "target": "reaction_10083861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNT1", "target": "species_10083858" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085096", "target": "A0A3Q1LNT1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083852", "target": "species_109277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083852", "target": "species_8851092" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8936166", "target": "reaction_10083852" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16039", "target": "species_8936166" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083849", "target": "reaction_10083852" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZH7", "target": "species_10083849" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063714", "target": "G3MZH7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083873", "target": "species_8851226" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083873", "target": "species_8851227" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8851224", "target": "reaction_10083873" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18075", "target": "species_8851224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18075", "target": "species_499999" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:18075", "target": "species_482803" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_8851227" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_500823" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_499997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_500420" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_500316" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_500414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109366", "target": "species_500347" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083870", "target": "reaction_10083873" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083870", "target": "reaction_10083876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M496", "target": "species_10083870" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071190", "target": "A0A3Q1M496" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083889", "target": "species_109277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083889", "target": "species_8851461" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8851462", "target": "reaction_10083889" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083886", "target": "reaction_10083889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJI4", "target": "species_10083886" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081265", "target": "Q2KJI4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083861", "target": "species_8870906" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083861", "target": "species_109277" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8870907", "target": "reaction_10083861" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083876", "target": "species_8851224" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083876", "target": "species_8851226" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8851233", "target": "reaction_10083876" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083926", "target": "species_8851513" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10083926", "target": "species_8851518" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8851517", "target": "reaction_10083926" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8851509", "target": "reaction_10083926" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10083923", "target": "reaction_10083926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MYV7", "target": "species_10083923" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000062934", "target": "G3MYV7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066684", "target": "species_10066677" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066684", "target": "species_10036828" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10066681", "target": "reaction_10066684" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081541", "target": "species_10081534" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081538", "target": "reaction_10081541" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083405", "target": "species_10081538" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066737", "target": "species_10066735" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066733", "target": "reaction_10066737" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066728", "target": "reaction_10066737" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069634", "target": "species_10066728" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069634", "target": "A0A3Q1M5Y5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5Y5", "target": "species_10066735" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10081877", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081877", "target": "species_10081870" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10081874", "target": "reaction_10081877" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052840", "target": "species_10081874" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066724", "target": "species_10066722" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066720", "target": "reaction_10066724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067101", "target": "species_10066720" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067101", "target": "A6QLF6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10066722", "target": "reaction_10072550" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF6", "target": "species_10066722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLF6", "target": "species_10072547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072550", "target": "species_2485002" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072550", "target": "species_10072547" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080811", "target": "species_10080809" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10080807", "target": "reaction_10080811" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWL2", "target": "species_10080807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWL2", "target": "species_10080809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083195", "target": "A0A3Q1LWL2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NE67", "target": "species_10080807" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NE67", "target": "species_10080809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082457", "target": "A0A3Q1NE67" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078666", "target": "reaction_10080811" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078666", "target": "reaction_10080797" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10078666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10080809" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10080795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10078664" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10088874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6J7", "target": "species_10088880" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007643", "target": "G3X6J7" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081530", "target": "species_10081528" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081526", "target": "reaction_10081530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007421", "target": "species_10081526" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007421", "target": "E1BLU8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLU8", "target": "species_10081528" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10080797", "target": "species_10080795" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10080793", "target": "reaction_10080797" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070207", "target": "species_10080793" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070207", "target": "A0A3Q1M2S9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2S9", "target": "species_10080795" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066764", "target": "species_10066762" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10066754", "target": "reaction_10066764" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007321", "target": "species_10066754" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007321", "target": "E1BMS9" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007321", "target": "species_10081885" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007321", "target": "species_10081887" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066760", "target": "reaction_10066764" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMS9", "target": "species_10066762" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10081889", "target": "species_10081887" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081885", "target": "reaction_10081889" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10081522", "target": "species_10081520" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081518", "target": "reaction_10081522" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077824", "target": "species_10081518" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077824", "target": "A0A3Q1MTW2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MTW2", "target": "species_10081520" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10078474", "target": "species_10078472" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10078470", "target": "reaction_10078474" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037102", "target": "reaction_10078474" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072571", "target": "species_29356" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072571", "target": "species_10072568" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072563", "target": "reaction_10072571" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E947", "target": "species_10072563" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E947", "target": "species_10072568" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E947", "target": "species_10072589" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004751", "target": "Q5E947" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072568", "target": "reaction_10072591" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072557", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10072557", "target": "species_29512" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10072554", "target": "reaction_10072557" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022146", "target": "species_10072554" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072591", "target": "species_10072589" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072587", "target": "reaction_10072591" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072587", "target": "reaction_10072595" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CN8", "target": "species_10072587" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CN8", "target": "species_10072589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CN8", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042886", "target": "Q58CN8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBI2", "target": "species_10072587" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBI2", "target": "species_10072589" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBI2", "target": "species_10072593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034532", "target": "A7MBI2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072595", "target": "species_10072593" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072614", "target": "species_10072612" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072610", "target": "reaction_10072614" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000187", "target": "species_10072610" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000187", "target": "Q08E62" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E62", "target": "species_10072612" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053210", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053210", "target": "species_29804" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053210", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053210", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053207", "target": "reaction_10053210" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXW4", "target": "species_10053207" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011569", "target": "F1MXW4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1C8", "target": "species_10053207" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073742", "target": "A0A3Q1M1C8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLX8", "target": "species_10053207" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026587", "target": "E1BLX8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053258", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053258", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053258", "target": "species_947588" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_947594", "target": "reaction_10053258" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053255", "target": "reaction_10053258" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ89", "target": "species_10053255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035192", "target": "F1MZ89" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MCF3", "target": "species_10053255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082277", "target": "A0A3Q1MCF3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M082", "target": "species_10053255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075591", "target": "A0A3Q1M082" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3G6", "target": "species_10053255" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021914", "target": "F1N3G6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076172", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076172", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076172", "target": "species_1981162" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076169", "target": "reaction_10076172" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009383", "target": "species_10076169" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076179", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076179", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076179", "target": "species_5692484" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5692450", "target": "reaction_10076179" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076176", "target": "reaction_10076179" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010946", "target": "species_10076176" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053143", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053143", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053143", "target": "species_167012" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053140", "target": "reaction_10053143" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LYD6", "target": "species_10053140" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086525", "target": "A0A3Q1LYD6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071254", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071254", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071254", "target": "species_5252016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5252122", "target": "reaction_10071254" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071251", "target": "reaction_10071254" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N272", "target": "species_10071251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021694", "target": "F1N272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M0A4", "target": "species_10071251" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077002", "target": "A0A3Q1M0A4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057787", "target": "species_10057778" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057787", "target": "species_379697" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057787", "target": "species_10057784" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_379721", "target": "reaction_10057787" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057762", "target": "reaction_10057787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCG0", "target": "species_10057762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCG0", "target": "species_10057778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCG0", "target": "species_10057790" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044551", "target": "Q0VCG0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B87", "target": "species_10057762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B87", "target": "species_10057778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B87", "target": "species_10057790" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001725", "target": "Q05B87" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QE6", "target": "species_10057762" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QE6", "target": "species_10057778" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17QE6", "target": "species_10057790" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015648", "target": "Q17QE6" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057776", "target": "reaction_10057787" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33738", "target": "species_10057776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00257", "target": "species_10057776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P00257", "target": "species_10057784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015660", "target": "P00257" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B51", "target": "species_10057776" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05B51", "target": "species_10057784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013630", "target": "Q05B51" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33739", "target": "species_10057778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33739", "target": "species_10086254" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:33737", "target": "species_10057784" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057792", "target": "species_10057762" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113531", "target": "reaction_10057792" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10057790", "target": "reaction_10057792" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10086272", "target": "species_10086252" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086272", "target": "species_10086266" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086254", "target": "reaction_10086272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLZ6", "target": "species_10086254" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017860", "target": "A6QLZ6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017860", "target": "species_10086252" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086264", "target": "reaction_10086272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZG8", "target": "species_10086264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZG8", "target": "species_10086266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079550", "target": "Q3SZG8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBG7", "target": "species_10086264" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBG7", "target": "species_10086266" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029272", "target": "Q2TBG7" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086270", "target": "reaction_10086272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000044111", "target": "species_10086270" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070682", "target": "species_10070680" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070678", "target": "reaction_10070682" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067320", "target": "reaction_10070682" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072346", "target": "species_10072328" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10072338", "target": "reaction_10072346" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DN8", "target": "species_10072338" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013135", "target": "Q08DN8" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070684", "target": "species_10067320" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10067318", "target": "reaction_10070684" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070689", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070689", "target": "species_10070686" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070531", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070531", "target": "species_10070526" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070524", "target": "reaction_10070531" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070524", "target": "reaction_10070534" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10070526", "target": "reaction_10070534" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10070529", "target": "reaction_10070531" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10070529", "target": "reaction_10070534" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070534", "target": "species_10067318" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070534", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061064", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061064", "target": "species_426910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629731", "target": "reaction_10061064" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060935", "target": "reaction_10061064" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060935", "target": "reaction_10061067" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060935", "target": "reaction_10060938" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P20456", "target": "species_10060935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015548", "target": "P20456" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZI8", "target": "species_10060935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077982", "target": "A0A3Q1LZI8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061067", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061067", "target": "species_426910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629753", "target": "reaction_10061067" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060986", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060986", "target": "species_1629739" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629739", "target": "reaction_10061061" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060509", "target": "reaction_10060986" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060938", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060938", "target": "species_426910" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_870330", "target": "reaction_10060938" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061134", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061134", "target": "species_1629746" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994123", "target": "reaction_10061134" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994123", "target": "reaction_10061014" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629746", "target": "reaction_10061046" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061058", "target": "reaction_10061134" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061058", "target": "reaction_10061061" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P21327", "target": "species_10061058" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084681", "target": "P21327" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061061", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061061", "target": "species_1629753" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061014", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061014", "target": "species_1629769" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061046", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061046", "target": "species_1629731" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044666", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044666", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044666", "target": "species_171095" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044663", "target": "reaction_10044666" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M833", "target": "species_10044663" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085091", "target": "A0A3Q1M833" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074493", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074493", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074493", "target": "species_5229279" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5682283", "target": "reaction_10074493" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074490", "target": "reaction_10074493" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004518", "target": "species_10074490" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046707", "target": "species_382571" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046707", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046707", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_382577", "target": "reaction_10046707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058216", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058216", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058216", "target": "species_1454919" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1454930", "target": "reaction_10058216" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058213", "target": "reaction_10058216" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ85", "target": "species_10058213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076899", "target": "A0A3Q1LZ85" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BNL1", "target": "species_10058213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007685", "target": "E1BNL1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4I6", "target": "species_10058213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014417", "target": "F1N4I6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3Y6", "target": "species_10058213" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026744", "target": "F1N3Y6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUC1", "target": "species_10058213" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074360", "target": "species_382539" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074360", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074360", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074357", "target": "reaction_10074360" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070307", "target": "species_10074357" }, { "type": "product", "sub_type": "", "source": "reaction_10070728", "target": "species_5223344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070728", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10070728", "target": "species_29370" }, { "type": "reactant", "sub_type": "", "source": "species_5223341", "target": "reaction_10070728" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10070725", "target": "reaction_10070728" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ87", "target": "species_10070725" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070992", "target": "A0A3Q1LZ87" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057832", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057832", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057832", "target": "species_1369027" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1369066", "target": "reaction_10057832" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057829", "target": "reaction_10057832" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D7P7", "target": "species_10057829" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027459", "target": "A5D7P7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046698", "target": "species_113548" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046698", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10046698", "target": "species_71185" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10046695", "target": "reaction_10046698" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MUB7", "target": "species_10046695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085390", "target": "A0A3Q1MUB7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058469", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058469", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058469", "target": "species_1467459" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1131652", "target": "reaction_10058469" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058466", "target": "reaction_10058469" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB23", "target": "species_10058466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080713", "target": "A0A3Q1MB23" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LS24", "target": "species_10058466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073046", "target": "A0A3Q1LS24" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10070743", "target": "species_10070741" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10070739", "target": "reaction_10070743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070886", "target": "species_10070739" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070886", "target": "A0A3Q1NB13" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NB13", "target": "species_10070741" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088584", "target": "species_10088582" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088550", "target": "reaction_10088584" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088550", "target": "reaction_10088554" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088550", "target": "reaction_10089578" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028703", "target": "species_10088550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028703", "target": "Q08DY6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056555", "target": "reaction_10088584" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10088582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10088552" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10088562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10089570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY6", "target": "species_10089572" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088554", "target": "species_10088552" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10056551", "target": "reaction_10088554" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088552", "target": "reaction_10088564" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089578", "target": "species_10089576" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089554", "target": "reaction_10089578" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013026", "target": "species_10089554" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013026", "target": "E1BJL2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089550", "target": "reaction_10089578" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10089550", "target": "reaction_10089574" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076903", "target": "species_10089550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076903", "target": "A6H7C4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066826", "target": "reaction_10089578" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10081545", "target": "reaction_10089578" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085264", "target": "species_10081545" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085264", "target": "A0A3Q1MS74" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS74", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS74", "target": "species_10089560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS74", "target": "species_10089572" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7C4", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H7C4", "target": "species_10089572" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL2", "target": "species_10089576" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL2", "target": "species_10089560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJL2", "target": "species_10089572" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088564", "target": "species_10088562" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088560", "target": "reaction_10088564" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKB7", "target": "species_10088560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKB7", "target": "species_10088562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKB7", "target": "species_10089570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKB7", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020143", "target": "E1BKB7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV00", "target": "species_10088560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV00", "target": "species_10088562" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV00", "target": "species_10089570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MV00", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069877", "target": "A0A3Q1MV00" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088596", "target": "species_10088594" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088592", "target": "reaction_10088596" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMR4", "target": "species_10088592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BMR4", "target": "species_10088594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077318", "target": "E1BMR4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF83", "target": "species_10088592" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LF83", "target": "species_10088594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077335", "target": "A0A3Q1LF83" }, { "type": "reactant", "sub_type": "", "source": "species_10088586", "target": "reaction_10088596" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10089574", "target": "species_10089572" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089570", "target": "reaction_10089574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N093", "target": "species_10089570" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N093", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016118", "target": "F1N093" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10089560", "target": "reaction_10089574" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC56", "target": "species_10089560" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC56", "target": "species_10089572" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064422", "target": "Q0VC56" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091049", "target": "species_10091047" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042669", "target": "reaction_10091049" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091096", "target": "species_427497" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091096", "target": "species_427498" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091096", "target": "species_10042665" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091084", "target": "reaction_10091096" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10042665", "target": "reaction_10091089" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091093", "target": "reaction_10091096" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E521", "target": "species_10091093" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E521", "target": "species_10075347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002648", "target": "G5E521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091089", "target": "species_2485002" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091089", "target": "species_10091084" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091086", "target": "reaction_10091089" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091184", "target": "species_10091182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJI7", "target": "species_10091182" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJI7", "target": "species_10042696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJI7", "target": "species_10091015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJI7", "target": "species_10091021" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091017", "target": "species_10091015" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10042696", "target": "reaction_10091017" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K5", "target": "species_10042696" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K5", "target": "species_10091015" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K5", "target": "species_10091027" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091033", "target": "species_10091031" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091013", "target": "reaction_10091033" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037662", "target": "reaction_10091033" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091023", "target": "species_10091021" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091019", "target": "reaction_10091023" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091029", "target": "species_10091027" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091025", "target": "reaction_10091029" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088872", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10088872", "target": "species_10088870" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10088870", "target": "reaction_10088876" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088876", "target": "species_10088874" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10078664", "target": "reaction_10088876" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088887", "target": "species_10078664" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10088880", "target": "reaction_10088887" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086458", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086458", "target": "species_10086455" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086449", "target": "reaction_10086458" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10055890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T0", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047968", "target": "F1N6T0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086449" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086455" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086504" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086506" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086513" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086515" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10086531" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI59", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004135", "target": "E1BI59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086493", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086493", "target": "species_10086490" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086477", "target": "reaction_10086493" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086509", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086509", "target": "species_10086506" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086504", "target": "reaction_10086509" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086525", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086525", "target": "species_10086522" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086520", "target": "reaction_10086525" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086541", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086541", "target": "species_10086538" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086536", "target": "reaction_10086541" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086502", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086502", "target": "species_10086499" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086497", "target": "reaction_10086502" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086518", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086518", "target": "species_10086515" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086513", "target": "reaction_10086518" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086534", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086534", "target": "species_10086531" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086529", "target": "reaction_10086534" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086638", "target": "species_10086636" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10086634", "target": "reaction_10086638" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005068", "target": "species_10086634" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005068", "target": "E1BIP8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063945", "target": "reaction_10086638" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIP8", "target": "species_10086636" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084922", "target": "species_10084920" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084918", "target": "reaction_10084922" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084918" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084879" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084877" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7U2", "target": "species_10084901" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072276", "target": "A0A3Q1M7U2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084916", "target": "reaction_10084922" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002913", "target": "species_10084916" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002913", "target": "Q32LE1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LE1", "target": "species_10084920" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10084911", "target": "species_10066845" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084905", "target": "reaction_10084911" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084905", "target": "reaction_10084909" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002671", "target": "species_10084905" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002671", "target": "species_10066845" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002671", "target": "Q0VC14" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10084907", "target": "reaction_10084911" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084907" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084879" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084893" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084877" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10066847" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084933" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC14", "target": "species_10084901" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084895", "target": "species_10084893" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084879", "target": "reaction_10084895" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084879", "target": "reaction_10084903" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084891", "target": "reaction_10084895" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ78", "target": "species_10084891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJ78", "target": "species_10084893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020109", "target": "Q2HJ78" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT9", "target": "species_10084891" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VCT9", "target": "species_10084893" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014907", "target": "Q0VCT9" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084881", "target": "species_10084879" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084877", "target": "reaction_10084881" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084935", "target": "species_10084933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069764", "target": "reaction_10084935" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077310", "target": "reaction_10084935" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066847", "target": "reaction_10084935" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084909", "target": "species_10084907" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084903", "target": "species_10084901" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084899", "target": "reaction_10084903" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068462", "target": "species_10084899" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068462", "target": "A0A3Q1MKM9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKM9", "target": "species_10084901" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063400", "target": "species_10063398" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063396", "target": "reaction_10063400" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063390", "target": "species_10063388" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063386", "target": "reaction_10063390" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085761", "target": "species_10085759" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10063394", "target": "reaction_10085761" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10046681", "target": "species_10046679" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10045690", "target": "reaction_10046681" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM20", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MM20", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072859", "target": "A0A3Q1MM20" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G9", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M5G9", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069224", "target": "A0A3Q1M5G9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXG9", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MXG9", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052227", "target": "F1MXG9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y9", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M9Y9", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073553", "target": "A0A3Q1M9Y9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML62", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1ML62", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018926", "target": "F1ML62" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKK0", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LKK0", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068928", "target": "A0A3Q1LKK0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5N2", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5N2", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070997", "target": "A0A3Q1N5N2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRQ5", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q7YRQ5", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016078", "target": "Q7YRQ5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGG2", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MGG2", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010892", "target": "F1MGG2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB3", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZPB3", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012145", "target": "A0A3S5ZPB3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04752", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q04752", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011869", "target": "Q04752" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZI4", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZI4", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074991", "target": "A0A3Q1LZI4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5I7", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5I7", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020641", "target": "G5E5I7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E53", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08E53", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004758", "target": "Q08E53" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8R7", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N8R7", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067712", "target": "A0A3Q1N8R7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY5", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q08DY5", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024159", "target": "Q08DY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7C1", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X7C1", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000087040", "target": "G3X7C1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3S3", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N3S3", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014791", "target": "F1N3S3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBX3", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBX3", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000036417", "target": "F1MBX3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N712", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N712", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010545", "target": "F1N712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3W3", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M3W3", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068282", "target": "A0A3Q1M3W3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWI2", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWI2", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023994", "target": "F1MWI2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC20", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC20", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022350", "target": "Q0VC20" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN19", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN19", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077017", "target": "F1MN19" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZU3", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZU3", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077868", "target": "A0A3Q1LZU3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18971", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18971", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083374", "target": "O18971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDU4", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDU4", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026059", "target": "A2VDU4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BML7", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BML7", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019772", "target": "E1BML7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN68", "target": "species_10045690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN68", "target": "species_10046679" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018594", "target": "F1MN68" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10054279", "target": "species_10054277" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10053367", "target": "reaction_10054279" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008424", "target": "species_10053367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008424", "target": "E1BJG5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10054275", "target": "reaction_10054279" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R08", "target": "species_10054275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q17R08", "target": "species_10054277" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080509", "target": "Q17R08" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJG5", "target": "species_10054277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065292", "target": "species_10065290" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065286", "target": "reaction_10065292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBP4", "target": "species_10065286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBP4", "target": "species_10065290" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046062", "target": "E1BBP4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065288", "target": "reaction_10065292" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068042", "target": "species_10068038" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10068042", "target": "species_10068040" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10068046", "target": "species_10068044" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10067891", "target": "species_10067889" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037981", "target": "reaction_10067891" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037981", "target": "reaction_10037985" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE56", "target": "species_10037981" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE56", "target": "species_10067889" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE56", "target": "species_10037983" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025281", "target": "E1BE56" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037985", "target": "species_10037983" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035396", "target": "species_10035390" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037991", "target": "species_10037989" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037987", "target": "reaction_10037991" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043049", "target": "species_10043047" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043049", "target": "species_10043045" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044762", "target": "species_10044758" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044762", "target": "species_10044760" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043014", "target": "reaction_10044762" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043014", "target": "reaction_10043021" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043014", "target": "reaction_10044756" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043021", "target": "species_10043018" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043021", "target": "species_10043016" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043059", "target": "species_10043057" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043059", "target": "species_10043055" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043053", "target": "reaction_10043059" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028855", "target": "species_10043053" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028855", "target": "species_10043057" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028855", "target": "species_10043055" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044756", "target": "species_10044743" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044756", "target": "species_10044745" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044923", "target": "species_10044912" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044923", "target": "species_10044910" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10040063", "target": "reaction_10044923" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044920", "target": "reaction_10044923" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044906", "target": "species_10044902" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044906", "target": "species_10044904" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044900", "target": "reaction_10044906" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075747", "target": "species_10044900" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075747", "target": "species_10044902" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075747", "target": "species_10044904" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075747", "target": "species_10044925" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044902", "target": "reaction_10044927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090573", "target": "species_10044920" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043039", "target": "species_10043037" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10043039", "target": "species_10043035" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044896", "target": "species_10044893" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044896", "target": "species_10044891" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044896", "target": "species_10044889" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044887", "target": "reaction_10044896" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044867", "target": "reaction_10044896" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044995", "target": "species_10044993" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044995", "target": "species_10044991" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10044989", "target": "reaction_10044995" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028199", "target": "species_10044989" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028199", "target": "species_10044993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028199", "target": "species_10044991" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10044927", "target": "species_10044925" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044869", "target": "species_10044867" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037723", "target": "species_10037718" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037723", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037723", "target": "species_10037721" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037716", "target": "reaction_10037723" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ55", "target": "species_10037716" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ55", "target": "species_10051177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ55", "target": "species_10051179" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ55", "target": "species_10051167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NJ55", "target": "species_10051173" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037721", "target": "reaction_10037727" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037727", "target": "species_10037725" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037706", "target": "species_10037704" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037695", "target": "reaction_10037706" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077917", "target": "species_10037695" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077917", "target": "species_10037704" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077917", "target": "Q05KI3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10037702", "target": "species_29370" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037702", "target": "species_10037695" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037702", "target": "species_10037692" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037690", "target": "reaction_10037702" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHR3", "target": "species_10037690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHR3", "target": "species_10037692" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006190", "target": "Q3MHR3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KI3", "target": "species_10037690" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KI3", "target": "species_10051177" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KI3", "target": "species_10051179" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051181", "target": "species_10051179" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037273", "target": "reaction_10051181" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037273", "target": "reaction_10037277" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051177", "target": "reaction_10051181" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037277", "target": "species_10037275" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051175", "target": "species_10051173" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10051171", "target": "reaction_10051175" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076163", "target": "species_10051171" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076163", "target": "Q05KJ0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10051167", "target": "reaction_10051175" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFP6", "target": "species_10051167" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NFP6", "target": "species_10051173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q05KJ0", "target": "species_10051173" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037289", "target": "species_10037287" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037283", "target": "reaction_10037289" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091191", "target": "species_10037291" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037281", "target": "reaction_10091191" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037281", "target": "reaction_10091197" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037281", "target": "reaction_10091188" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091197", "target": "species_10091195" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091193", "target": "reaction_10091197" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXU1", "target": "species_10091193" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MXU1", "target": "species_10091195" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091188", "target": "species_10037283" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039930", "target": "species_175979" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039930", "target": "species_71285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_175973", "target": "reaction_10039930" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038238", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038238", "target": "species_71285" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038238", "target": "species_158611" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158619", "target": "reaction_10038238" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038235", "target": "reaction_10038238" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025698", "target": "species_10038235" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076898", "target": "species_5696211" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076898", "target": "species_71285" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696224", "target": "reaction_10076898" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076895", "target": "reaction_10076898" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076895", "target": "reaction_10076900" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069974", "target": "species_10076895" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071924", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071924", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071924", "target": "species_71284" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071921", "target": "reaction_10071924" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RI9", "target": "species_10071921" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016399", "target": "Q29RI9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MZ37", "target": "species_10071921" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075325", "target": "A0A3Q1MZ37" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076900", "target": "species_71285" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076900", "target": "species_5696214" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696216", "target": "reaction_10076900" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696214", "target": "reaction_10076903" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035863", "target": "species_143501" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035863", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035863", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035863", "target": "species_33153" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_76384", "target": "reaction_10035863" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076903", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076903", "target": "species_5696224" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076903", "target": "species_111745" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039980", "target": "reaction_10076903" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ08", "target": "species_10039980" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJ08", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017435", "target": "E1BJ08" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037800", "target": "species_10037765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037800", "target": "species_10037577" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037763", "target": "reaction_10037800" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037763", "target": "reaction_10037852" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037795", "target": "reaction_10037800" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037795", "target": "reaction_10090183" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037798", "target": "reaction_10037800" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037852", "target": "species_10037765" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037852", "target": "species_10037577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037785", "target": "reaction_10037852" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037785", "target": "reaction_10090181" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10037850", "target": "reaction_10037852" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037948", "target": "species_10037945" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10037921", "target": "reaction_10037948" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037945", "target": "reaction_10037950" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037950", "target": "species_10037829" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037950", "target": "species_9693058" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9693058", "target": "reaction_10037927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037923", "target": "species_10037921" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037919", "target": "reaction_10037923" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071906", "target": "species_10037843" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037841", "target": "reaction_10071906" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037835", "target": "reaction_10071906" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090181", "target": "species_10037850" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9038743", "target": "reaction_10090181" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9038743", "target": "reaction_10090183" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037845", "target": "species_10037813" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10037845", "target": "species_10037819" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037817", "target": "reaction_10037845" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10037813", "target": "reaction_10037815" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037815", "target": "species_10037795" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090183", "target": "species_10037798" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10037927", "target": "species_10037919" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10037925", "target": "reaction_10037927" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055529", "target": "species_10055527" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29868", "target": "reaction_10055529" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_29868", "target": "species_10055527" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055525", "target": "reaction_10055529" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE93", "target": "species_10055525" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE93", "target": "species_10055527" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025252", "target": "E1BE93" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025252", "target": "species_10055519" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055995", "target": "species_10055993" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055991", "target": "reaction_10055995" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY73", "target": "species_10055991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7YY73", "target": "species_10055993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028574", "target": "A7YY73" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJV0", "target": "species_10055991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5PJV0", "target": "species_10055993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000044", "target": "A5PJV0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD3", "target": "species_10055991" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5EAD3", "target": "species_10055993" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066479", "target": "Q5EAD3" }, { "type": "reactant", "sub_type": "", "source": "species_1008228", "target": "reaction_10055995" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055933", "target": "species_10055931" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055926", "target": "reaction_10055933" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055929", "target": "reaction_10055933" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055870", "target": "species_10055868" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055855", "target": "reaction_10055870" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008198", "target": "species_10055855" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008198", "target": "F2Z4J7" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055866", "target": "reaction_10055870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F2Z4J7", "target": "species_10055868" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055649", "target": "species_10055525" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10055519", "target": "reaction_10055649" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055920", "target": "species_10055918" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055890", "target": "reaction_10055920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBZ5", "target": "species_10055890" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBZ5", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002161", "target": "E1BBZ5" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055916", "target": "reaction_10055920" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC01", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MC01", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066877", "target": "A0A3Q1MC01" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1M2", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N1M2", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007537", "target": "F1N1M2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGB0", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGB0", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071546", "target": "A0A3Q1MGB0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N551", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N551", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007134", "target": "F1N551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZJ5", "target": "species_10055916" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZJ5", "target": "species_10055918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027184", "target": "Q3SZJ5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056002", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10056002", "target": "species_113525" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10055999", "target": "reaction_10056002" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022789", "target": "species_10055999" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10055847", "target": "species_10055845" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10055843", "target": "reaction_10055847" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10085753", "target": "species_10085751" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085749", "target": "reaction_10085753" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX90", "target": "species_10085749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LX90", "target": "species_10085751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085051", "target": "A0A3Q1LX90" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085051", "target": "A0A3Q1MS45" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7Z2", "target": "species_10085749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7Z2", "target": "species_10085751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081146", "target": "A0A3Q1M7Z2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS45", "target": "species_10085749" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MS45", "target": "species_10085751" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10085701", "target": "reaction_10085753" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043323", "target": "species_10043321" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043319", "target": "reaction_10043323" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043319", "target": "reaction_10043363" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080737", "target": "species_10043319" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080737", "target": "A4IFI9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFI9", "target": "species_10043321" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFI9", "target": "species_10043361" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043355", "target": "species_10043353" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043351", "target": "reaction_10043355" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043375", "target": "species_10043373" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043367", "target": "reaction_10043375" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014924", "target": "species_10043367" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014924", "target": "Q2KHZ6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043371", "target": "reaction_10043375" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084280", "target": "species_10043371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084280", "target": "A0A3Q1LFU5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LFU5", "target": "species_10043373" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHZ6", "target": "species_10043373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044024", "target": "species_10044022" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044030", "target": "species_10044028" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10044028", "target": "reaction_10044039" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044034", "target": "species_10044032" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044039", "target": "species_10044036" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044039", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043393", "target": "species_10043391" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043379", "target": "reaction_10043393" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029578", "target": "species_10043379" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029578", "target": "F1MS77" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10043389", "target": "reaction_10043393" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P98107", "target": "species_10043389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P98107", "target": "species_10043391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P98107", "target": "species_10066261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009612", "target": "P98107" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009612", "target": "species_10043387" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJA9", "target": "species_10043389" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJA9", "target": "species_10043391" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000057091", "target": "Q2KJA9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS77", "target": "species_10043391" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS77", "target": "species_10066259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MS77", "target": "species_10066261" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043363", "target": "species_10043361" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043359", "target": "reaction_10043363" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043359", "target": "reaction_10043397" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081263", "target": "species_10043359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081263", "target": "A0A3Q1M4F2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F2", "target": "species_10043361" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M4F2", "target": "species_10043395" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043347", "target": "species_10043345" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043343", "target": "reaction_10043347" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043339", "target": "reaction_10043347" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022936", "target": "species_10043339" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022936", "target": "Q148M9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q148M9", "target": "species_10043345" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043397", "target": "species_10043395" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10043335", "target": "species_10043333" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043331", "target": "reaction_10043335" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053223", "target": "species_10043331" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000053223", "target": "F1N7U9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7U9", "target": "species_10043333" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10066263", "target": "species_10066261" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10066259", "target": "reaction_10066263" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL67", "target": "species_10066259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LL67", "target": "species_10066261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083484", "target": "A0A3Q1LL67" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQP5", "target": "species_10066259" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQP5", "target": "species_10066261" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037368", "target": "A6QQP5" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10043387", "target": "reaction_10066263" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038329", "target": "species_10038326" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038260", "target": "reaction_10038329" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038260", "target": "reaction_10038270" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038324", "target": "reaction_10038329" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038285", "target": "species_10038260" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038285", "target": "species_10038267" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038272", "target": "reaction_10038285" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038267", "target": "reaction_10038303" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038267", "target": "reaction_10038270" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038267", "target": "reaction_10038292" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038283", "target": "reaction_10038285" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P60902", "target": "species_10038283" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020150", "target": "P60902" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038303", "target": "species_10038298" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038296", "target": "reaction_10038303" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038296", "target": "reaction_10038307" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038300", "target": "reaction_10038303" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038300", "target": "reaction_10038307" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038270", "target": "species_10038248" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038248", "target": "reaction_10038288" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10038248", "target": "reaction_10038307" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038288", "target": "species_10038254" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038252", "target": "reaction_10038288" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038252", "target": "reaction_10038292" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038254", "target": "reaction_10038263" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038307", "target": "species_10038305" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038290", "target": "species_10038267" }, { "type": "reactant", "sub_type": "", "source": "species_157771", "target": "reaction_10038290" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038265", "target": "reaction_10038290" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038292", "target": "species_10038272" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038263", "target": "species_10038260" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10038263", "target": "species_10038248" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10057598", "target": "species_10057596" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057594", "target": "reaction_10057598" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013434", "target": "species_10057594" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013434", "target": "species_10057592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013434", "target": "G5E5C6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013434", "target": "species_10057602" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10057592", "target": "reaction_10057598" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E5C6", "target": "species_10057596" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057605", "target": "species_10057594" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10057605", "target": "species_10057592" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10057602", "target": "reaction_10057605" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091211", "target": "species_10091209" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091207", "target": "reaction_10091211" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091201", "target": "reaction_10091211" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084434", "target": "species_10091201" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084434", "target": "A0A3Q1M1H9" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091209", "target": "reaction_10091222" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1H9", "target": "species_10091209" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1H9", "target": "species_10091237" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1H9", "target": "species_10091230" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1H9", "target": "species_10091226" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M1H9", "target": "species_10091219" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10091566", "target": "species_10091564" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10091562", "target": "reaction_10091566" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035854", "target": "species_10035852" }, { "type": "reactant", "sub_type": "", "source": "species_76050", "target": "reaction_10035854" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035850", "target": "reaction_10035854" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016732", "target": "species_10035850" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016732", "target": "F1MUY9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUY9", "target": "species_10035852" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036760", "target": "species_10036757" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036760", "target": "species_110242" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036755", "target": "reaction_10036760" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091240", "target": "species_9629439" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091240", "target": "species_10091230" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091237", "target": "reaction_10091240" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036782", "target": "species_5635947" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036782", "target": "species_10036779" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036777", "target": "reaction_10036782" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K4", "target": "species_10036777" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4K4", "target": "species_10036779" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014928", "target": "F1N4K4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036798", "target": "species_10036788" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036798", "target": "species_110249" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036795", "target": "reaction_10036798" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKN2", "target": "species_10036795" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKN2", "target": "species_10036788" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKN2", "target": "species_10036802" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKN2", "target": "species_10036786" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000037548", "target": "F1MKN2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091233", "target": "species_10091230" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091233", "target": "species_9629218" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10091226", "target": "reaction_10091233" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036805", "target": "species_10036788" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036805", "target": "species_29850" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036802", "target": "reaction_10036805" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036791", "target": "species_10036788" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036791", "target": "species_30947" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036786", "target": "reaction_10036791" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091222", "target": "species_10091219" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091222", "target": "species_9629218" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072876", "target": "species_10072874" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10072868", "target": "reaction_10072876" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000131", "target": "species_10072868" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000131", "target": "E1BKF4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072872", "target": "reaction_10072876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10072872" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10072874" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10072878" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036840" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036850" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N5S1", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076791", "target": "A0A3Q1N5S1" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10072874", "target": "reaction_10072883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKF4", "target": "species_10072874" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072883", "target": "species_10072868" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072883", "target": "species_10072880" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10072883", "target": "species_10072878" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073302", "target": "species_10073300" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073294", "target": "reaction_10073302" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054209", "target": "species_10073294" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000054209", "target": "Q5E9B2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q5E9B2", "target": "species_10073300" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044547", "target": "species_194236" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044547", "target": "species_171076" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_171149", "target": "reaction_10044547" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_194276", "target": "reaction_10044547" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10044544", "target": "reaction_10044547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024018", "target": "species_10044544" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088982", "target": "species_174602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088982", "target": "species_174675" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10088979", "target": "reaction_10088982" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LR40", "target": "species_10088979" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075023", "target": "A0A3Q1LR40" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084509", "target": "species_10077482" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077472", "target": "reaction_10084509" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071232", "target": "species_10077472" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071232", "target": "A0A3Q1MPP4" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077480", "target": "reaction_10084509" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1678620", "target": "species_10077480" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1678620", "target": "species_10077482" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1678620", "target": "reaction_10077489" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11151", "target": "species_10077480" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11151", "target": "species_10077482" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P11151", "target": "species_10077478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017086", "target": "P11151" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017086", "target": "species_10077476" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077482", "target": "reaction_10077487" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPP4", "target": "species_10077482" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10077487", "target": "species_10077476" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10077487", "target": "species_10077472" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077487", "target": "species_1678620" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077484", "target": "reaction_10077487" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077489", "target": "species_10077480" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077478", "target": "reaction_10077489" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077593", "target": "species_10077508" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077506", "target": "reaction_10077593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071085", "target": "species_10077506" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071085", "target": "A0A3Q1MT39" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077502", "target": "reaction_10077593" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065656", "target": "species_10077502" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000065656", "target": "Q2KHY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY5", "target": "species_10077508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY5", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY5", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KHY5", "target": "species_10077569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT39", "target": "species_10077508" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT39", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT39", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT39", "target": "species_10077569" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077625", "target": "species_10077623" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077619", "target": "reaction_10077625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN11", "target": "species_10077619" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BN11", "target": "species_10077623" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026896", "target": "E1BN11" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10077582", "target": "reaction_10077625" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE83", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE83", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BE83", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013299", "target": "E1BE83" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP1", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP1", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIP1", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018787", "target": "A0A452DIP1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWV7", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWV7", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MWV7", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009509", "target": "F1MWV7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6X8", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6X8", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B6X8", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002478", "target": "E1B6X8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ29", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ29", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQ29", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056722", "target": "A6QQ29" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X787", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X787", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X787", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082853", "target": "G3X787" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN8", "target": "species_10077582" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN8", "target": "species_10077623" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2TBN8", "target": "species_10077569" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007713", "target": "Q2TBN8" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10077609", "target": "reaction_10077625" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085708", "target": "species_10077609" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085708", "target": "A0A3Q1MJE2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MJE2", "target": "species_10077623" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077591", "target": "species_10077588" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077591", "target": "species_10077582" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077569", "target": "reaction_10077591" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ26", "target": "species_10077569" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MQ26", "target": "species_10077588" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068467", "target": "A0A3Q1MQ26" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035372", "target": "species_29374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035372", "target": "species_73917" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035369", "target": "reaction_10035372" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005088", "target": "species_10035369" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035363", "target": "species_113529" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035363", "target": "species_73909" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035363", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035363", "target": "species_113526" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035363", "target": "species_73911" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049883", "target": "species_10049881" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049879", "target": "reaction_10049883" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049879", "target": "reaction_10049891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081787", "target": "species_10049879" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081787", "target": "A0A3Q1LMM6" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049875", "target": "reaction_10049883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMM6", "target": "species_10049881" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMM6", "target": "species_10049889" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049312", "target": "species_10049310" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049308", "target": "reaction_10049312" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084501", "target": "species_10049308" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084501", "target": "A0A3Q1M7B6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M7B6", "target": "species_10049310" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049891", "target": "species_10049889" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10049887", "target": "reaction_10049891" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082961", "target": "species_10049887" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082961", "target": "A0A3Q1MET9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MET9", "target": "species_10049889" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038942", "target": "species_10035753" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036844", "target": "species_10036842" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036840", "target": "reaction_10036844" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036809", "target": "reaction_10036844" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066497", "target": "species_10036809" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066497", "target": "A0A3Q1MPW7" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036842", "target": "reaction_10036853" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPW7", "target": "species_10036842" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MPW7", "target": "species_10036850" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036853", "target": "species_10036850" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073275", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073275", "target": "species_10073272" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10073275", "target": "species_10036857" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073270", "target": "reaction_10073275" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10073277" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10073287" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10036863" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10036876" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10036883" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZ79", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007900", "target": "F1MZ79" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007900", "target": "species_10036857" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D979", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D979", "target": "species_10073272" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A5D979", "target": "species_10073252" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008030", "target": "A5D979" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008030", "target": "species_10073250" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7U2", "target": "species_10073270" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N7U2", "target": "species_10073272" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042613", "target": "F1N7U2" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036857", "target": "reaction_10073279" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036857", "target": "reaction_10036869" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073290", "target": "species_10073287" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10073290", "target": "species_10036867" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10073277", "target": "reaction_10073290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFE2", "target": "species_10073277" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009461", "target": "A4IFE2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009461", "target": "species_10036867" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10036867", "target": "reaction_10073279" }, { "type": "inhibitor", "sub_type": "protein_component", "source": "species_10036867", "target": "reaction_10036869" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036879", "target": "species_10036876" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036879", "target": "species_113541" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036863", "target": "reaction_10036879" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036876", "target": "reaction_10036886" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073279", "target": "species_10073277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036869", "target": "species_10036863" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036861", "target": "reaction_10036869" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036886", "target": "species_10036883" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036886", "target": "species_113541" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036883", "target": "reaction_10073254" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10073254", "target": "species_10073252" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10073250", "target": "reaction_10073254" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090392", "target": "species_9025012" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090394", "target": "species_9024012" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090462", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090462", "target": "species_9024873" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090384", "target": "species_9024522" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090464", "target": "species_29364" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090464", "target": "species_9025001" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090458", "target": "species_9024799" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090458", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9024764", "target": "reaction_10090458" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:132797", "target": "species_9024799" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:132800", "target": "species_9024799" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064497", "target": "reaction_10090458" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064497", "target": "reaction_10064500" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10064497", "target": "reaction_10090440" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q309F3", "target": "species_10064497" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027024", "target": "Q309F3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090390", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090390", "target": "species_9024815" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090390", "target": "species_111745" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090371", "target": "reaction_10090390" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090371", "target": "reaction_10090388" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090371", "target": "reaction_10090374" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10090371", "target": "reaction_10090379" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090388", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090388", "target": "species_9024463" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090388", "target": "species_111745" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062377", "target": "species_10058697" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062335", "target": "reaction_10062377" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058697", "target": "reaction_10058705" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062368", "target": "reaction_10062377" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062375", "target": "reaction_10062377" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2HJB6", "target": "species_10062375" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027347", "target": "Q2HJB6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MKP1", "target": "species_10062375" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021330", "target": "F1MKP1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061787", "target": "species_1650769" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061787", "target": "species_159751" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10061787", "target": "species_10061784" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061734", "target": "reaction_10061787" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:29073", "target": "species_10061734" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:29073", "target": "species_10061784" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY3", "target": "species_10061734" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QLY3", "target": "species_10061784" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027999", "target": "A6QLY3" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1650779", "target": "reaction_10061787" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060187", "target": "species_10060185" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10060185", "target": "reaction_10060191" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10087626", "target": "species_10061923" }, { "type": "reactant", "sub_type": "", "source": "species_10061921", "target": "reaction_10087626" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10061791", "target": "reaction_10087626" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050322", "target": "species_10061791" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000050322", "target": "F1N0V8" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061923", "target": "reaction_10062058" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0V8", "target": "species_10061923" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0V8", "target": "species_10062055" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062058", "target": "species_10062055" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10062058", "target": "species_158602" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1981137", "target": "reaction_10062058" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062055", "target": "reaction_10087628" }, { "type": "product", "sub_type": "", "source": "reaction_10087628", "target": "species_10062053" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10087628", "target": "species_10061791" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10060191", "target": "species_10060189" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064337", "target": "species_10064335" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062852", "target": "reaction_10064337" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10062352", "target": "species_10062335" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10062205", "target": "reaction_10062352" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10062349", "target": "reaction_10062352" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BC50", "target": "species_10062349" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061447", "target": "E1BC50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFV4", "target": "species_10062349" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028224", "target": "E1BFV4" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063799", "target": "species_10063797" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10063799", "target": "species_10062846" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10063637", "target": "reaction_10063799" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJH6", "target": "species_10063637" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083385", "target": "Q2KJH6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083385", "target": "species_10062846" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064491", "target": "species_2161856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9032038", "target": "reaction_10064491" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6499", "target": "species_2161856" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_2161759", "target": "species_2161856" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2161759", "target": "reaction_10064500" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064500", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064500", "target": "species_2142761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10064500", "target": "species_73473" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065691", "target": "species_10065689" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10062553", "target": "reaction_10065691" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065300", "target": "species_10065298" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065296", "target": "reaction_10065300" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064953", "target": "species_10064951" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10058703", "target": "reaction_10064953" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064959", "target": "species_10064957" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064955", "target": "reaction_10064959" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10058705", "target": "species_10058703" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065929", "target": "species_10065920" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065926", "target": "reaction_10065929" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15858", "target": "species_10065926" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMN6", "target": "species_10065926" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073028", "target": "A0A3Q1LMN6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035464", "target": "species_31633" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035464", "target": "species_30064" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035461", "target": "reaction_10035464" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX9", "target": "species_10035461" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015339", "target": "F1MLX9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088571", "target": "species_8953344" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088571", "target": "species_83956" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109327", "target": "reaction_10088571" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109327", "target": "species_500120" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109327", "target": "species_500125" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109327", "target": "species_500222" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109327", "target": "species_500199" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088568", "target": "reaction_10088571" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026530", "target": "species_10088568" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035453", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035453", "target": "species_500172" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035453", "target": "species_113599" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035453", "target": "species_500244" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500172", "target": "reaction_10035453" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28997", "target": "species_500172" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28997", "target": "species_500118" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28997", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28997", "target": "species_500224" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_113599", "target": "reaction_10035453" }, { "type": "product", "sub_type": "complex_component", "source": "species_500244", "target": "reaction_10035453" }, { "type": "product", "sub_type": "complex_component", "source": "species_500244", "target": "reaction_10035455" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500244", "target": "reaction_10035479" }, { "type": "product", "sub_type": "complex_component", "source": "species_500244", "target": "reaction_10035481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28542", "target": "species_500244" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035450", "target": "reaction_10035453" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035450", "target": "reaction_10035455" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036207", "target": "species_500104" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036207", "target": "species_109277" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500101", "target": "reaction_10036207" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035455", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035455", "target": "species_500245" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035455", "target": "species_83956" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035455", "target": "species_500244" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500245", "target": "reaction_10035455" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17172", "target": "species_500245" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17172", "target": "species_500118" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17172", "target": "species_500124" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17172", "target": "species_500224" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17172", "target": "species_500201" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036238", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036238", "target": "species_83909" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036235", "target": "reaction_10036238" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006950", "target": "species_10036235" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036256", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036256", "target": "species_500118" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500120", "target": "reaction_10036256" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036253", "target": "reaction_10036256" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036253", "target": "reaction_10036258" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3X6X2", "target": "species_10036253" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015317", "target": "G3X6X2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036231", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036231", "target": "species_500124" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500125", "target": "reaction_10036231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036226", "target": "reaction_10036231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036226", "target": "reaction_10036229" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BF39", "target": "species_10036226" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003884", "target": "E1BF39" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10053044", "target": "species_10053041" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10053044", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10053039", "target": "reaction_10053044" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC92", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0VC92", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025615", "target": "Q0VC92" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY5", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHY5", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004528", "target": "A0A452DHY5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRF2", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRF2", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000075557", "target": "A0A3Q1LRF2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR16", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QR16", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078713", "target": "A6QR16" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBL6", "target": "species_10053039" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MBL6", "target": "species_10053041" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027632", "target": "F1MBL6" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10090377", "target": "species_9022921" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9023653", "target": "species_9022921" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9023653", "target": "reaction_10090379" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_9020583", "target": "species_9022921" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9020583", "target": "reaction_10090374" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090440", "target": "species_9023963" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090440", "target": "species_73473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090396", "target": "species_9022679" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9020474", "target": "reaction_10090396" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090374", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090374", "target": "species_9020474" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090374", "target": "species_111745" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090379", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090379", "target": "species_9023651" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090379", "target": "species_111745" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9023651", "target": "reaction_10090382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10090382", "target": "species_9023644" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065866", "target": "species_74016" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065861", "target": "reaction_10065866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9V5", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B9V5", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024903", "target": "E1B9V5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHU9", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHU9", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002352", "target": "A0A452DHU9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MED0", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MED0", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000056871", "target": "F1MED0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGU6", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGU6", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000045580", "target": "E1BGU6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N390", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N390", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019622", "target": "F1N390" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP0", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3MZP0", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000063395", "target": "G3MZP0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4E7", "target": "species_10065861" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N4E7", "target": "species_10065863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019586", "target": "F1N4E7" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065884", "target": "species_351626" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1132304", "target": "reaction_10065884" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065881", "target": "reaction_10065884" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065886", "target": "species_10065861" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065863", "target": "reaction_10065886" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1449667", "target": "reaction_10065886" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10065875", "target": "species_74126" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10065872", "target": "reaction_10065875" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3S5ZP59", "target": "species_10065872" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038859", "target": "A0A3S5ZP59" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076856", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076856", "target": "species_2022135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076856", "target": "species_351629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076856", "target": "species_5696128" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076853", "target": "reaction_10076856" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077496", "target": "species_29702" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077496", "target": "species_561052" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6784964", "target": "reaction_10077496" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077493", "target": "reaction_10077496" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000008368", "target": "species_10077493" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076475", "target": "species_5694091" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5694080", "target": "reaction_10076475" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076472", "target": "reaction_10076475" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083641", "target": "species_10076472" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076863", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076863", "target": "species_2022135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076863", "target": "species_351629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076863", "target": "species_5696178" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696181", "target": "reaction_10076863" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10076860", "target": "reaction_10076863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000042833", "target": "species_10076860" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076884", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076884", "target": "species_5696154" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076884", "target": "species_2022135" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076884", "target": "species_351629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5696148", "target": "reaction_10076884" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076881", "target": "reaction_10076884" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q9TTK6", "target": "species_10076881" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081083", "target": "Q9TTK6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081083", "target": "Q29437" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DHX8", "target": "species_10076881" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001383", "target": "A0A452DHX8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29437", "target": "species_10076881" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076375", "target": "species_156540" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076375", "target": "species_5693711" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076375", "target": "species_5693712" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693702", "target": "reaction_10076375" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076372", "target": "reaction_10076375" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MU22", "target": "species_10076372" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000032343", "target": "F1MU22" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086550", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086550", "target": "species_8937418" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8937424", "target": "reaction_10086550" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10086547", "target": "reaction_10086550" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024873", "target": "species_10086547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044524", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044524", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044524", "target": "species_217269" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044521", "target": "reaction_10044524" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M207", "target": "species_10044521" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079411", "target": "A0A3Q1M207" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044533", "target": "species_113519" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044533", "target": "species_113564" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10044533", "target": "species_217320" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_217315", "target": "reaction_10044533" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044530", "target": "reaction_10044533" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G5E540", "target": "species_10044530" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003873", "target": "G5E540" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034175", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034175", "target": "species_29416" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034175", "target": "species_73473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034206", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034206", "target": "species_29510" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034206", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30203", "target": "reaction_10034206" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034203", "target": "reaction_10034206" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BBW9", "target": "species_10034203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020879", "target": "E1BBW9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZN9", "target": "species_10034203" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009191", "target": "F1MZN9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050160", "target": "species_159448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050160", "target": "species_159450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050160", "target": "species_113559" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_113539", "target": "reaction_10050160" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050157", "target": "reaction_10050160" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086374", "target": "species_10050157" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076144", "target": "species_5692249" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076144", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076144", "target": "species_73473" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5692221", "target": "reaction_10076144" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076141", "target": "reaction_10076144" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZC42", "target": "species_10076141" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021304", "target": "Q3ZC42" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034215", "target": "species_113529" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034215", "target": "species_29362" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034215", "target": "species_113539" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034231", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034231", "target": "species_76183" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034231", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034228", "target": "reaction_10034231" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078990", "target": "species_10034228" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078990", "target": "A0A3Q1MB37" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075404", "target": "species_5689001" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075404", "target": "species_5688995" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5689006", "target": "reaction_10075404" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10075401", "target": "reaction_10075404" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015373", "target": "species_10075401" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086543", "target": "species_10035975" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035973", "target": "reaction_10086543" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035969", "target": "reaction_10086543" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086469", "target": "species_8936514" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10086469", "target": "species_8936507" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8936516", "target": "reaction_10086469" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8936520", "target": "reaction_10086469" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10086466", "target": "reaction_10086469" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZT2", "target": "species_10086466" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072063", "target": "Q3SZT2" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_209934", "target": "reaction_10086469" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_1130942", "target": "reaction_10086469" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077734", "target": "species_6786194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077734", "target": "species_6786179" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6786175", "target": "reaction_10077734" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077731", "target": "reaction_10077734" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072469", "target": "species_10077731" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041241", "target": "species_6814795" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041241", "target": "species_174602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088973", "target": "species_174602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088973", "target": "species_174675" }, { "type": "catalyst", "sub_type": "", "source": "species_10088970", "target": "reaction_10088973" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041239", "target": "species_174602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10041239", "target": "species_174675" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076274", "target": "species_5693410" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076274", "target": "species_29968" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5693375", "target": "reaction_10076274" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076271", "target": "reaction_10076274" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P56965", "target": "species_10076271" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000049235", "target": "P56965" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SX44", "target": "species_10076271" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085909", "target": "Q3SX44" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040617", "target": "species_70115" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040617", "target": "species_188995" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188973", "target": "reaction_10040617" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040614", "target": "reaction_10040617" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BK89", "target": "species_10040614" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020185", "target": "E1BK89" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040872", "target": "species_188986" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040872", "target": "species_70115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191103", "target": "reaction_10040872" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_191103", "target": "reaction_10040866" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188986", "target": "reaction_10040629" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_188986", "target": "reaction_10040868" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040626", "target": "reaction_10040872" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040626", "target": "reaction_10040629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040620", "target": "species_189049" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040620", "target": "species_70115" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040605", "target": "reaction_10040620" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040605", "target": "reaction_10040608" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040605", "target": "reaction_10040866" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040605", "target": "reaction_10073378" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040605", "target": "reaction_10040868" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGH5", "target": "species_10040605" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023366", "target": "E1BGH5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040608", "target": "species_191103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040608", "target": "species_188986" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040608", "target": "species_70115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189108", "target": "reaction_10040608" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040595", "target": "species_191103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040595", "target": "species_188986" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_189075", "target": "reaction_10040595" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040592", "target": "reaction_10040595" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040592", "target": "reaction_10040870" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MJQ3", "target": "species_10040592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082976", "target": "F1MJQ3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MP21", "target": "species_10040592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060970", "target": "F1MP21" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LQY4", "target": "species_10040592" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083621", "target": "A0A3Q1LQY4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040866", "target": "species_188986" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040866", "target": "species_70115" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10073378", "target": "species_70115" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5659875", "target": "reaction_10073378" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040629", "target": "species_70115" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040868", "target": "species_70115" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040870", "target": "species_191103" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040870", "target": "species_188986" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040870", "target": "species_189108" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_189071", "target": "reaction_10040870" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10086435", "target": "species_10086433" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086431", "target": "reaction_10086435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5B2", "target": "species_10086431" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5B2", "target": "species_10086433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026286", "target": "F1N5B2" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10086425", "target": "reaction_10086435" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM0", "target": "species_10086425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM0", "target": "species_10086433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009466", "target": "E1BIM0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM1", "target": "species_10086425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BIM1", "target": "species_10086433" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009465", "target": "E1BIM1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036917", "target": "species_10036911" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039865", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039865", "target": "species_174393" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039865", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_174393", "target": "reaction_10057079" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10039862", "target": "reaction_10039865" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MN33", "target": "species_10039862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000081594", "target": "A0A3Q1MN33" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2T9Y6", "target": "species_10039862" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026855", "target": "Q2T9Y6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087515", "target": "species_210382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087515", "target": "species_1247934" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071751", "target": "reaction_10087515" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071751", "target": "reaction_10071754" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077658", "target": "species_1247942" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077658", "target": "species_1247904" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10077655", "target": "reaction_10077658" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6H738", "target": "species_10077655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013689", "target": "A6H738" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q0IIH4", "target": "species_10077655" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025922", "target": "Q0IIH4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057079", "target": "species_111707" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10057079", "target": "species_1247942" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10057076", "target": "reaction_10057079" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32LE4", "target": "species_10057076" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014010", "target": "Q32LE4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075362", "target": "species_5688281" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075362", "target": "species_10037239" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075362", "target": "species_5688340" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5688282", "target": "reaction_10075362" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075353", "target": "reaction_10075362" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075359", "target": "reaction_10075362" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZBQ0", "target": "species_10075359" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072664", "target": "Q3ZBQ0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075350", "target": "species_5688337" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075350", "target": "species_5688274" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075350", "target": "species_10075341" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10075337", "target": "reaction_10075350" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB37", "target": "species_10075337" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB37", "target": "species_10075341" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075347", "target": "reaction_10075350" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072271", "target": "species_10072263" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10072271", "target": "species_10072267" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10072269", "target": "reaction_10072271" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q58CS6", "target": "species_10072269" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084852", "target": "Q58CS6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084852", "target": "species_10072263" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058751", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058751", "target": "species_113528" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058748", "target": "reaction_10058751" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058748", "target": "reaction_10058755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MAE5", "target": "species_10058748" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071702", "target": "A0A3Q1MAE5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZX4", "target": "species_10058748" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020243", "target": "Q3SZX4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058753", "target": "species_351626" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058753", "target": "species_425425" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058719", "target": "reaction_10058753" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058719", "target": "reaction_10058722" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MI50", "target": "species_10058719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000067395", "target": "A0A3Q1MI50" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BPA4", "target": "species_10058719" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015174", "target": "E1BPA4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058755", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058755", "target": "species_111627" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058722", "target": "species_109276" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058722", "target": "species_1237009" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058772", "target": "species_113521" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058772", "target": "species_29376" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058769", "target": "reaction_10058772" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10058769", "target": "reaction_10058774" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LWK4", "target": "species_10058769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068215", "target": "A0A3Q1LWK4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N5D1", "target": "species_10058769" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027210", "target": "F1N5D1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058774", "target": "species_29896" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10058774", "target": "species_113529" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040030", "target": "species_176048" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_158543", "target": "reaction_10040030" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_176065", "target": "reaction_10040030" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159211", "target": "species_176065" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_159211", "target": "species_5423723" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:29132", "target": "species_176065" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:29132", "target": "species_176070" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32639", "target": "species_176048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32639", "target": "species_176049" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:2505", "target": "species_176048" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:35896", "target": "species_176048" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040027", "target": "reaction_10040030" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040027", "target": "reaction_10071717" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KJG4", "target": "species_10040027" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029028", "target": "Q2KJG4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067425", "target": "species_3301973" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10067425", "target": "species_3301969" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_3301954", "target": "reaction_10067425" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3301954", "target": "species_176070" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_3301969", "target": "species_176049" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10067422", "target": "reaction_10067425" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRG0", "target": "species_10067422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012969", "target": "F1MRG0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10040021", "target": "species_176049" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_176070", "target": "reaction_10040021" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30614", "target": "species_176070" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:34479", "target": "species_176049" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10040018", "target": "reaction_10040021" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKD8", "target": "species_10040018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKD8", "target": "species_10091609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BKD8", "target": "species_10091607" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035828", "target": "E1BKD8" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035828", "target": "F1MX44" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX44", "target": "species_10040018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX44", "target": "species_10091609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MX44", "target": "species_10091607" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18879", "target": "species_10040018" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18879", "target": "species_10091609" }, { "type": "complex_component", "sub_type": "protein_component", "source": "O18879", "target": "species_10091607" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000046354", "target": "O18879" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2NL00", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007403", "target": "Q2NL00" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A1A4L7", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021896", "target": "A1A4L7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LSN6", "target": "species_10040018" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085178", "target": "A0A3Q1LSN6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076133", "target": "species_5692216" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076133", "target": "species_29364" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5692212", "target": "reaction_10076133" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040185", "target": "species_159448" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040185", "target": "species_159450" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10040185", "target": "species_177137" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_177153", "target": "reaction_10040185" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038316", "target": "species_76194" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10038316", "target": "species_10038314" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038311", "target": "reaction_10038316" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10038311", "target": "reaction_10039918" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048506", "target": "species_10038311" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000048506", "target": "species_10038314" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038314", "target": "reaction_10039921" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10038314", "target": "reaction_10039923" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10039918", "target": "species_76194" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039918", "target": "species_10038314" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039921", "target": "species_10038311" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039921", "target": "species_174960" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_174969", "target": "reaction_10039921" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:45373", "target": "species_174969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:30753", "target": "species_174969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:27565", "target": "species_174969" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63845", "target": "species_174960" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16395", "target": "species_174960" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16395", "target": "species_174958" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63815", "target": "species_174960" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:63817", "target": "species_174960" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10039923", "target": "species_10038311" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10039923", "target": "species_174958" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_174971", "target": "reaction_10039923" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:6030", "target": "species_174971" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:7207", "target": "species_174958" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:32643", "target": "species_174958" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071722", "target": "species_5423660" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071722", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071722", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423605", "target": "reaction_10071722" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423605", "target": "reaction_10038060" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423605", "target": "reaction_10071727" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423605", "target": "reaction_10071729" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071719", "target": "reaction_10071722" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071754", "target": "species_210382" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071754", "target": "species_5490235" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5490253", "target": "reaction_10071754" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78581", "target": "species_5490253" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78581", "target": "species_5423730" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78587", "target": "species_5490253" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78587", "target": "species_5423730" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78579", "target": "species_5490235" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78584", "target": "species_5490235" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038060", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038060", "target": "species_159211" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10038060", "target": "species_29366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10038057", "target": "reaction_10038060" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071727", "target": "species_5423663" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071727", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071727", "target": "species_29366" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_5423663", "target": "species_5423723" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071724", "target": "reaction_10071727" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071729", "target": "species_5423629" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071729", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071729", "target": "species_29366" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423629", "target": "reaction_10071715" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071712", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071712", "target": "species_5423729" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_5423727", "target": "reaction_10071712" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071709", "target": "reaction_10071712" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MZC0", "target": "species_10071709" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016300", "target": "F1MZC0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6I4", "target": "species_10071709" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038217", "target": "F1N6I4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071715", "target": "species_29356" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071715", "target": "species_5423657" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071715", "target": "species_29366" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035869", "target": "reaction_10071715" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10071763", "target": "species_2022890" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071763", "target": "species_5490231" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5490236", "target": "reaction_10071763" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78580", "target": "species_5490236" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78585", "target": "species_5490236" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78583", "target": "species_5490231" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:78578", "target": "species_5490231" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10071760", "target": "reaction_10071763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MR63", "target": "species_10071760" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000024787", "target": "F1MR63" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071717", "target": "species_5423730" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_5423723", "target": "reaction_10071717" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074761", "target": "species_10074755" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074753", "target": "reaction_10074761" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074751", "target": "reaction_10074761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016216", "target": "species_10074751" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016216", "target": "Q3SYV6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016216", "target": "species_10074757" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074755", "target": "reaction_10074759" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SYV6", "target": "species_10074755" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035720", "target": "species_10035718" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035716", "target": "reaction_10035720" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035710", "target": "reaction_10035720" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035712", "target": "species_10035710" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035708", "target": "reaction_10035712" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10035704", "target": "reaction_10035712" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074759", "target": "species_10035716" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074759", "target": "species_10074757" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074747", "target": "species_10074745" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074743", "target": "reaction_10074747" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069360", "target": "species_10074743" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069360", "target": "A0A3Q1MU04" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074733", "target": "reaction_10074747" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074733", "target": "reaction_10074736" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074733", "target": "reaction_10074739" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MU04", "target": "species_10074745" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074558", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074558", "target": "species_10074555" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074548", "target": "reaction_10074558" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B782", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B782", "target": "species_10074555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018496", "target": "E1B782" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000018496", "target": "species_10069553" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074674" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074667" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074542" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074544" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074546" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10076288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10076290" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BI26", "target": "species_10074665" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000035900", "target": "E1BI26" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV15", "target": "species_10074548" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV15", "target": "species_10074555" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001000", "target": "A4FV15" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001000", "target": "species_10069303" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074736", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10074736", "target": "species_10074727" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10074724", "target": "reaction_10074736" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074020", "target": "species_10074724" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074020", "target": "species_10074727" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074727", "target": "reaction_10074739" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074739", "target": "species_113550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074739", "target": "species_10074663" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074663", "target": "reaction_10076329" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074677", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074677", "target": "species_10074667" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074674", "target": "reaction_10074677" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074667", "target": "reaction_10074670" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074679", "target": "species_10074544" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074542", "target": "reaction_10074679" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074550", "target": "species_10074548" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069303", "target": "reaction_10074550" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074546", "target": "reaction_10074550" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10069553", "target": "reaction_10074550" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076329", "target": "species_10076290" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076288", "target": "reaction_10076329" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076290", "target": "reaction_10076293" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076332", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076332", "target": "species_10074530" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074530", "target": "reaction_10076334" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076303", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076303", "target": "species_10074733" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076300", "target": "reaction_10076303" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076334", "target": "species_10076300" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074715", "target": "reaction_10076334" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074670", "target": "species_77502" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074670", "target": "species_10074542" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074720", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074720", "target": "species_10074715" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074711", "target": "reaction_10074720" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10074717", "target": "reaction_10074720" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076293", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076293", "target": "species_10074665" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075173", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10075173", "target": "species_10075170" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10075167", "target": "reaction_10075173" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049230", "target": "species_430042" }, { "type": "product", "sub_type": "", "source": "reaction_10049230", "target": "species_429925" }, { "type": "reactant", "sub_type": "", "source": "species_429926", "target": "reaction_10049230" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049227", "target": "reaction_10049230" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003732", "target": "species_10049227" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10049232", "target": "species_10049221" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10049219", "target": "reaction_10049232" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQV3", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQV3", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007405", "target": "A6QQV3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA6", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DIA6", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009684", "target": "A0A452DIA6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T3", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T3", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000005939", "target": "F1N6T3" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2U2", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M2U2", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069947", "target": "A0A3Q1M2U2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMH1", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LMH1", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072254", "target": "A0A3Q1LMH1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX5", "target": "species_10049219" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LRX5", "target": "species_10049221" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077566", "target": "A0A3Q1LRX5" }, { "type": "reactant", "sub_type": "", "source": "species_429974", "target": "reaction_10049232" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061043", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061043", "target": "species_2024016" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2024002", "target": "reaction_10061043" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060960", "target": "reaction_10061043" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060960", "target": "reaction_10060963" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060960", "target": "reaction_10061122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000007784", "target": "species_10060960" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060963", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060963", "target": "species_2024012" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2024008", "target": "reaction_10060963" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061122", "target": "species_113551" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061122", "target": "species_2564836" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2024018", "target": "reaction_10061122" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036907", "target": "species_10036905" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035351", "target": "reaction_10036907" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035351", "target": "reaction_10035354" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17909", "target": "species_10035351" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:17909", "target": "species_10036905" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV22", "target": "species_10035351" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MV22", "target": "species_10036905" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000052667", "target": "F1MV22" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10036905", "target": "reaction_10036909" }, { "type": "catalyst", "sub_type": "metabolite_component", "source": "species_29602", "target": "reaction_10036907" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29602", "target": "reaction_10036928" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_29602", "target": "reaction_10035319" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035339", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035339", "target": "species_111370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035339", "target": "species_29370" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111369", "target": "reaction_10035339" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111370", "target": "reaction_10035332" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035336", "target": "reaction_10035339" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035336", "target": "reaction_10035342" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035336", "target": "reaction_10035345" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000012108", "target": "species_10035336" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_73566" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_29356" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_29472" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_111292" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035354", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_111292", "target": "reaction_10035354" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111292", "target": "reaction_10035345" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036909", "target": "species_10035351" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035308", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035308", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035308", "target": "species_113578" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035308", "target": "species_76577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111584", "target": "reaction_10035308" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_111584", "target": "reaction_10035319" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10035305", "target": "reaction_10035308" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084984", "target": "species_10035305" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091727", "target": "species_10035317" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_9678719", "target": "reaction_10091727" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10035314", "target": "reaction_10091727" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035314", "target": "reaction_10035319" }, { "type": "inhibitor", "sub_type": "complex_component", "source": "species_10035317", "target": "reaction_10035319" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035342", "target": "species_111354" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035342", "target": "species_111355" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111338", "target": "reaction_10035342" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_419151", "target": "reaction_10035342" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035345", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035345", "target": "species_111338" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035345", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035329", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035329", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035329", "target": "species_111399" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_111395", "target": "reaction_10035329" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035326", "target": "reaction_10035329" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035326", "target": "reaction_10035332" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN04", "target": "species_10035326" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000013985", "target": "F1MN04" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036928", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036928", "target": "species_29420" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036928", "target": "species_35141" }, { "type": "inhibitor", "sub_type": "metabolite_component", "source": "species_35141", "target": "reaction_10036928" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036925", "target": "reaction_10036928" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBG0", "target": "species_10036925" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047061", "target": "A7MBG0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035332", "target": "species_111395" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035319", "target": "species_70106" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035319", "target": "species_111584" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035319", "target": "species_73473" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10076312", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076312", "target": "species_10075286" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076309", "target": "reaction_10076312" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10076309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10075286" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10075288" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10075292" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10076283" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BLB6", "target": "species_10076314" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022631", "target": "E1BLB6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022631", "target": "species_10076305" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076347", "target": "species_10076309" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076305", "target": "reaction_10076347" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076345", "target": "reaction_10076347" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10075295", "target": "species_113582" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10075295", "target": "species_10075292" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075288", "target": "reaction_10075295" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10075292", "target": "reaction_10076286" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076286", "target": "species_10076283" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10076283", "target": "reaction_10076327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076327", "target": "species_10076314" }, { "type": "catalyst", "sub_type": "", "source": "species_10076324", "target": "reaction_10076327" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036649", "target": "species_500761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036649", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500759", "target": "reaction_10036649" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500759", "target": "reaction_10034989" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500759", "target": "reaction_10088624" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036646", "target": "reaction_10036649" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LZ00", "target": "species_10036646" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077740", "target": "A0A3Q1LZ00" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034989", "target": "species_500761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034989", "target": "species_29370" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034986", "target": "reaction_10034989" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DII0", "target": "species_10034986" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014316", "target": "A0A452DII0" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035020", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035020", "target": "species_109366" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035017", "target": "reaction_10035020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NEX0", "target": "species_10035017" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073714", "target": "A0A3Q1NEX0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035007", "target": "species_500430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035007", "target": "species_31633" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500829", "target": "reaction_10035007" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500829", "target": "reaction_10034980" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15698", "target": "species_500829" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15698", "target": "species_500822" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:15698", "target": "species_500346" }, { "type": "product", "sub_type": "complex_component", "source": "species_500430", "target": "reaction_10035479" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500430", "target": "reaction_10035481" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16450", "target": "species_500430" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16450", "target": "species_500822" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16450", "target": "species_500421" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16450", "target": "species_500415" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16450", "target": "species_500346" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035004", "target": "reaction_10035007" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10088624", "target": "species_500761" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10088624", "target": "species_29370" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10088621", "target": "reaction_10088624" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071389", "target": "species_10088621" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10034980", "target": "species_500828" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034980", "target": "species_29370" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_500828" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_500823" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109378", "target": "reaction_10034971" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_500009" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_6788778" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_6788802" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_109378", "target": "species_500347" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034977", "target": "reaction_10034980" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034977", "target": "reaction_10036308" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3MHR2", "target": "species_10034977" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016449", "target": "Q3MHR2" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035479", "target": "species_83962" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035479", "target": "species_500244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035479", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035479", "target": "species_500430" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_83962", "target": "reaction_10035479" }, { "type": "product", "sub_type": "metabolite_component", "source": "species_83962", "target": "reaction_10035481" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035476", "target": "reaction_10035479" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035476", "target": "reaction_10035481" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0Y0", "target": "species_10035476" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000011088", "target": "F1N0Y0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MGK3", "target": "species_10035476" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000082335", "target": "A0A3Q1MGK3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036614", "target": "species_113581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036614", "target": "species_500823" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500822", "target": "reaction_10036614" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500742", "target": "species_500823" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500742", "target": "species_499997" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500742", "target": "species_500420" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500742", "target": "species_500414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500742", "target": "species_500347" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036611", "target": "reaction_10036614" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000064369", "target": "species_10036611" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069313", "target": "species_10069311" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10069309", "target": "reaction_10069313" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3A0", "target": "species_10069309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3A0", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3A0", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N3A0", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000073403", "target": "A0A3Q1N3A0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T1", "target": "species_10069309" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T1", "target": "species_10069311" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T1", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N0T1", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023245", "target": "F1N0T1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044515", "target": "species_10044513" }, { "type": "reactant", "sub_type": "", "source": "species_10044511", "target": "reaction_10044515" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065555", "target": "species_10065553" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065551", "target": "reaction_10065555" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9E9", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N9E9", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069112", "target": "A0A3Q1N9E9" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDD5", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MDD5", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000060991", "target": "F1MDD5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNS6", "target": "species_10065551" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QNS6", "target": "species_10065553" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009531", "target": "A6QNS6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047065", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047065", "target": "species_8848577" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10047065", "target": "species_76194" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8848577", "target": "reaction_10083575" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10047062", "target": "reaction_10047065" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000014725", "target": "species_10047062" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083577", "target": "species_76194" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083577", "target": "species_2534407" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_30209", "target": "reaction_10083577" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2534407", "target": "reaction_10083547" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083575", "target": "species_8848499" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083575", "target": "species_76194" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091611", "target": "species_10091607" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091611", "target": "species_189386" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091609", "target": "reaction_10091611" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10091607", "target": "reaction_10091613" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_189386", "target": "reaction_10091613" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10091613", "target": "species_10091609" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091598", "target": "species_189386" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9661418", "target": "reaction_10091598" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_9661418", "target": "reaction_10091605" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10091605", "target": "species_189386" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10091602", "target": "reaction_10091605" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10069412", "target": "species_10069410" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074474", "target": "species_10074467" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10074474", "target": "species_76194" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074459", "target": "reaction_10074474" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG24", "target": "species_10074459" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG24", "target": "species_10074467" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MG24", "target": "species_10074478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000027538", "target": "F1MG24" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10074467", "target": "reaction_10074486" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10074471", "target": "reaction_10074474" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000006197", "target": "species_10074471" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10074486", "target": "species_10074478" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10076091", "target": "species_10076089" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10059181", "target": "species_5691103" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10059178", "target": "reaction_10059181" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10076083", "target": "species_10076074" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10076005", "target": "reaction_10076083" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077304", "target": "species_10076005" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077304", "target": "species_10076074" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10076080", "target": "reaction_10076083" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10052866", "target": "species_435347" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_917828", "target": "reaction_10052866" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10052863", "target": "reaction_10052866" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLZ1", "target": "species_10052863" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000010387", "target": "F1MLZ1" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10052916", "target": "species_10052874" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087646", "target": "species_8949232" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10087646", "target": "species_2889083" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2889072", "target": "reaction_10087646" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_8949220", "target": "reaction_10087646" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10087643", "target": "reaction_10087646" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061116", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061116", "target": "species_1629755" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1629755", "target": "species_2023943" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060953", "target": "reaction_10061116" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060953", "target": "reaction_10060956" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060953", "target": "reaction_10061034" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060953", "target": "reaction_10061037" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10060953", "target": "reaction_10061125" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060956", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060956", "target": "species_1629759" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629765", "target": "reaction_10060956" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629765", "target": "reaction_10061040" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629765", "target": "reaction_10061024" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061040", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061040", "target": "species_1629770" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060977", "target": "reaction_10061040" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060977", "target": "reaction_10060980" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060977", "target": "reaction_10063018" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060977", "target": "reaction_10063020" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV0", "target": "species_10060977" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A2VDV0", "target": "species_10060969" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000009797", "target": "A2VDV0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MBH2", "target": "species_10060977" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085197", "target": "A7MBH2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061011", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061011", "target": "species_1629770" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061008", "target": "reaction_10061011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060980", "target": "species_1629765" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060980", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2023968", "target": "reaction_10060980" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2023968", "target": "reaction_10063020" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1629732", "target": "species_2023968" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:62924", "target": "species_2023968" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060983", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060983", "target": "species_994141" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2023943", "target": "reaction_10060983" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1629736", "target": "species_2023943" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629736", "target": "reaction_10061034" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:62927", "target": "species_2023943" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060969", "target": "reaction_10060983" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061079", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061079", "target": "species_1629740" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_1629740", "target": "species_2023974" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_1629740", "target": "reaction_10061037" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061021", "target": "reaction_10061079" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10061021", "target": "reaction_10061024" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000072742", "target": "species_10061021" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061034", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061034", "target": "species_1629738" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063018", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063018", "target": "species_1629770" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_2023974", "target": "reaction_10063018" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:62922", "target": "species_2023974" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061037", "target": "species_1629732" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061037", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10063020", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10063020", "target": "species_2023974" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061024", "target": "species_1629732" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061024", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061125", "target": "species_1629765" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061125", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061113", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061113", "target": "species_114519" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061110", "target": "reaction_10061113" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BJE0", "target": "species_10061110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000034821", "target": "E1BJE0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MTE8", "target": "species_10061110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000078103", "target": "F1MTE8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M8P8", "target": "species_10061110" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000085120", "target": "A0A3Q1M8P8" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061084", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061084", "target": "species_994123" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_994170", "target": "reaction_10061084" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061081", "target": "reaction_10061084" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061006", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061006", "target": "species_114519" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061003", "target": "reaction_10061006" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q1RML2", "target": "species_10061003" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017574", "target": "Q1RML2" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060917", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10060917", "target": "species_994170" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10060914", "target": "reaction_10060917" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LNH2", "target": "species_10060914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070709", "target": "A0A3Q1LNH2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MN32", "target": "species_10060914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000025930", "target": "F1MN32" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FV33", "target": "species_10060914" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000002194", "target": "A4FV33" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061076", "target": "species_114520" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10061076", "target": "species_1500596" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_2023856", "target": "reaction_10061076" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10061073", "target": "reaction_10061076" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LJY0", "target": "species_10061073" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000074483", "target": "A0A3Q1LJY0" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036003", "target": "species_10034250" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10034244", "target": "reaction_10036003" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10034248", "target": "reaction_10036003" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084424", "target": "species_10084422" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084420", "target": "reaction_10084424" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUX1", "target": "species_10084420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4FUX1", "target": "species_10084422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083406", "target": "A4FUX1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUM0", "target": "species_10084420" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1LUM0", "target": "species_10084422" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000079299", "target": "A0A3Q1LUM0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8866926", "target": "reaction_10084424" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_8866926", "target": "reaction_10084694" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084480", "target": "species_10084478" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10084476", "target": "reaction_10084480" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFN5", "target": "species_10084476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A4IFN5", "target": "species_10084478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026679", "target": "A4IFN5" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ11", "target": "species_10084476" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DJ11", "target": "species_10084478" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000028518", "target": "A0A452DJ11" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10084694", "target": "species_10084692" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10084690", "target": "reaction_10084694" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038453", "target": "species_10084690" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000038453", "target": "Q29RS1" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q29RS1", "target": "species_10084692" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083544", "target": "species_8876730" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083544", "target": "species_76103" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083541", "target": "reaction_10083544" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10083541", "target": "reaction_10083547" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000021067", "target": "species_10083541" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083547", "target": "species_8848337" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10083547", "target": "species_30209" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10071388", "target": "species_10071386" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10071384", "target": "reaction_10071388" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHQ4", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MHQ4", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000079", "target": "F1MHQ4" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q09139", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q09139", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017593", "target": "Q09139" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFF7", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MFF7", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022662", "target": "F1MFF7" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRS8", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MRS8", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000867", "target": "F1MRS8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10790", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P10790", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000022375", "target": "P10790" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N125", "target": "species_10071384" }, { "type": "complex_component", "sub_type": "protein_component", "source": "G3N125", "target": "species_10071386" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000066006", "target": "G3N125" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035435", "target": "species_111294" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035435", "target": "species_76577" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035432", "target": "reaction_10035435" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051215", "target": "species_29366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051215", "target": "species_29602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051215", "target": "species_31633" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051212", "target": "reaction_10051215" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MCZ0", "target": "species_10051212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000003519", "target": "F1MCZ0" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F6R1R5", "target": "species_10051212" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020904", "target": "F6R1R5" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036001", "target": "species_29602" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036001", "target": "species_31633" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035998", "target": "reaction_10036001" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MLX6", "target": "species_10035998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000015348", "target": "F1MLX6" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1M723", "target": "species_10035998" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000080896", "target": "A0A3Q1M723" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035426", "target": "species_113581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035426", "target": "species_500222" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500224", "target": "reaction_10035426" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035423", "target": "reaction_10035426" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q2KIN2", "target": "species_10035423" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047239", "target": "Q2KIN2" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036306", "target": "species_500088" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036306", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500173", "target": "reaction_10036306" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036303", "target": "reaction_10036306" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MB39", "target": "species_10036303" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000071820", "target": "A0A3Q1MB39" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036308", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036308", "target": "species_500199" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500201", "target": "reaction_10036308" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035444", "target": "species_111294" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035444", "target": "species_500260" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500259", "target": "reaction_10035444" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035441", "target": "reaction_10035444" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3SZ18", "target": "species_10035441" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000019547", "target": "Q3SZ18" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050378", "target": "species_113582" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050378", "target": "species_10050298" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050287", "target": "reaction_10050378" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050287", "target": "reaction_10050368" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000805", "target": "species_10050287" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000805", "target": "species_10050298" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000805", "target": "Q3ZCE2" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000805", "target": "species_10050293" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050298", "target": "reaction_10051221" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10050375", "target": "reaction_10050378" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050368", "target": "species_10050289" }, { "type": "reactant", "sub_type": "", "source": "species_450613", "target": "reaction_10050368" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050289" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050304" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050398" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050295" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050302" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q3ZCE2", "target": "species_10050300" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050400", "target": "species_10050398" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10050400", "target": "species_10050382" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050304", "target": "reaction_10050400" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P51122", "target": "species_10050304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016410", "target": "P51122" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000016410", "target": "species_10050269" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MH31", "target": "species_10050304" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029190", "target": "F1MH31" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029190", "target": "species_10050273" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051219", "target": "species_10050295" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050293", "target": "reaction_10051219" }, { "type": "reactant", "sub_type": "", "source": "species_450605", "target": "reaction_10051219" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050306", "target": "species_10050304" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050261", "target": "reaction_10050306" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050273", "target": "reaction_10050306" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050302", "target": "reaction_10050306" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050269", "target": "reaction_10050306" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051221", "target": "species_10050300" }, { "type": "reactant", "sub_type": "", "source": "species_517622", "target": "reaction_10051221" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051066", "target": "species_10051064" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050363", "target": "reaction_10051066" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB98", "target": "species_10050363" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB98", "target": "species_10051064" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB98", "target": "species_10050357" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB98", "target": "species_10050314" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A7MB98", "target": "species_10050316" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084778", "target": "A7MB98" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000084778", "target": "species_10050355" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10050366", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050366", "target": "species_10050363" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050357", "target": "reaction_10050366" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050318", "target": "species_10050316" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10050314", "target": "reaction_10050318" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050373", "target": "species_10050357" }, { "type": "reactant", "sub_type": "", "source": "species_450523", "target": "reaction_10050373" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050355", "target": "reaction_10050373" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050408", "target": "species_10050406" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050402", "target": "reaction_10050408" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050371", "target": "reaction_10050408" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070369", "target": "species_10050371" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070369", "target": "A0A3Q1N6L6" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070369", "target": "species_10050322" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6L6", "target": "species_10050406" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N6L6", "target": "species_10050324" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10050380", "target": "species_10050324" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10050322", "target": "reaction_10050380" }, { "type": "reactant", "sub_type": "", "source": "species_450386", "target": "reaction_10050380" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049346", "target": "species_3632881" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_400452", "target": "reaction_10049346" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049343", "target": "reaction_10049346" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049351", "target": "species_1132084" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049351", "target": "species_200993" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10049351", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10049348", "target": "reaction_10049351" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044634", "target": "species_6790050" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10044634", "target": "species_10044619" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10044615", "target": "reaction_10044634" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10047765", "target": "species_10046205" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034971", "target": "species_109382" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034971", "target": "species_31633" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_109382", "target": "reaction_10034998" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034968", "target": "reaction_10034971" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A6QQC3", "target": "species_10034968" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000083533", "target": "A6QQC3" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035038", "target": "species_29372" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035038", "target": "species_29404" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035038", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035038", "target": "species_110614" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035035", "target": "reaction_10035038" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0JNE9", "target": "species_10035035" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000068403", "target": "A0JNE9" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035698", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035698", "target": "species_500006" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035698", "target": "species_500009" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035698", "target": "species_113592" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500006", "target": "reaction_10035698" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28846", "target": "species_500006" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28846", "target": "species_6788782" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28846", "target": "species_482803" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28846", "target": "species_6788801" }, { "type": "product", "sub_type": "complex_component", "source": "species_500009", "target": "reaction_10035698" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10034909", "target": "reaction_10035698" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026582", "target": "species_10034909" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035029", "target": "species_499997" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035029", "target": "species_113592" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035029", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035029", "target": "species_499999" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_499997", "target": "reaction_10035029" }, { "type": "product", "sub_type": "complex_component", "source": "species_499999", "target": "reaction_10035029" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28850", "target": "species_499999" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28850", "target": "species_482803" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035026", "target": "reaction_10035029" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1N7A8", "target": "species_10035026" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000069715", "target": "A0A3Q1N7A8" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036692", "target": "species_29370" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036692", "target": "species_113592" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036692", "target": "species_76577" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036689", "target": "reaction_10036692" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000023406", "target": "species_10036689" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034998", "target": "species_109366" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034998", "target": "species_73604" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034995", "target": "reaction_10034998" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1NID0", "target": "species_10034995" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000077973", "target": "A0A3Q1NID0" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10036683", "target": "species_29370" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10036683", "target": "species_6788782" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036683", "target": "species_6788778" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036683", "target": "species_113592" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6788782", "target": "reaction_10036683" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16174", "target": "species_6788782" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16174", "target": "species_482803" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:16174", "target": "species_6788801" }, { "type": "product", "sub_type": "complex_component", "source": "species_6788778", "target": "reaction_10036683" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6788778", "target": "reaction_10036685" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036680", "target": "reaction_10036683" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036680", "target": "reaction_10036685" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MKM8", "target": "species_10036680" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000076708", "target": "A0A3Q1MKM8" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B7Q2", "target": "species_10036680" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000061550", "target": "E1B7Q2" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1MUF5", "target": "species_10036680" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000020294", "target": "F1MUF5" }, { "type": "product", "sub_type": "protein_component", "source": "reaction_10036938", "target": "species_10036932" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036938", "target": "species_111745" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10036935", "target": "reaction_10036938" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001575", "target": "species_10036935" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000001575", "target": "species_10036932" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036685", "target": "species_29370" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036685", "target": "species_6788782" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10051075", "target": "species_113593" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10051075", "target": "species_482803" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10051075", "target": "species_113581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10051075", "target": "species_482807" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_482803", "target": "reaction_10051075" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28862", "target": "species_482803" }, { "type": "product", "sub_type": "complex_component", "source": "species_482807", "target": "reaction_10051075" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "species_500739", "target": "species_482807" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_500739", "target": "reaction_10035047" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10051072", "target": "reaction_10051075" }, { "type": "complex_component", "sub_type": "protein_component", "source": "F1N6T4", "target": "species_10051072" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000047964", "target": "F1N6T4" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10077890", "target": "species_113581" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10077890", "target": "species_6788801" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_6788802", "target": "reaction_10077890" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10077887", "target": "reaction_10077890" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043366", "target": "species_10077887" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082948", "target": "species_113581" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10082948", "target": "species_6810471" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_6810468", "target": "reaction_10082948" }, { "type": "catalyst", "sub_type": "protein_component", "source": "species_10082945", "target": "reaction_10082948" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000000407", "target": "species_10082945" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035047", "target": "species_113541" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035047", "target": "species_500742" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10035044", "target": "reaction_10035047" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MT44", "target": "species_10035044" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000070515", "target": "A0A3Q1MT44" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "reaction_10035481", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "reaction_10035481", "target": "species_500430" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035481", "target": "species_83962" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10035481", "target": "species_500244" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034953", "target": "species_73588" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73584", "target": "reaction_10034953" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73588", "target": "reaction_10034962" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034950", "target": "reaction_10034953" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034950", "target": "reaction_10035009" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BFN6", "target": "species_10034950" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000029176", "target": "E1BFN6" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036267", "target": "species_113548" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036267", "target": "species_500421" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500420", "target": "reaction_10036267" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28895", "target": "species_500420" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28895", "target": "species_500414" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28070", "target": "species_500420" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:28070", "target": "species_500414" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036264", "target": "reaction_10036267" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1B8C1", "target": "species_10036264" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000043576", "target": "E1B8C1" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036209", "target": "species_109277" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036209", "target": "species_500318" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500316", "target": "reaction_10036209" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035009", "target": "species_73617" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73541", "target": "reaction_10035009" }, { "type": "reactant", "sub_type": "metabolite_component", "source": "species_73617", "target": "reaction_10035011" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035011", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035011", "target": "species_73619" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10035011", "target": "species_31633" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034959", "target": "reaction_10035011" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10034959", "target": "reaction_10034962" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A3Q1MFR9", "target": "species_10034959" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000086038", "target": "A0A3Q1MFR9" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036258", "target": "species_29372" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036258", "target": "species_500415" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500414", "target": "reaction_10036258" }, { "type": "complex_component", "sub_type": "metabolite_component", "source": "CHEBI:46322", "target": "species_500414" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034962", "target": "species_113528" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034962", "target": "species_73590" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10034962", "target": "species_31633" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036229", "target": "species_500346" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036229", "target": "species_29372" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500347", "target": "reaction_10036229" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_500347", "target": "reaction_10036247" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10036247", "target": "species_500346" }, { "type": "product", "sub_type": "metabolite_component", "source": "reaction_10036247", "target": "species_29372" }, { "type": "catalyst", "sub_type": "complex_component", "source": "species_10036244", "target": "reaction_10036247" }, { "type": "complex_component", "sub_type": "protein_component", "source": "Q32L46", "target": "species_10036244" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000033700", "target": "Q32L46" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065163", "target": "species_10065161" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10065129", "target": "reaction_10065163" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P85521", "target": "species_10065129" }, { "type": "complex_component", "sub_type": "protein_component", "source": "P85521", "target": "species_10065161" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000026215", "target": "P85521" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064765", "target": "species_10064763" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064755", "target": "reaction_10064765" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI25", "target": "species_10064755" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI25", "target": "species_10064763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI25", "target": "species_10064751" }, { "type": "complex_component", "sub_type": "protein_component", "source": "A0A452DI25", "target": "species_10065171" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004635", "target": "A0A452DI25" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000004635", "target": "species_10064747" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10064761", "target": "reaction_10064765" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017556", "target": "species_10064761" }, { "type": "gene_component", "sub_type": "gene", "source": "ENSBTAT00000017556", "target": "E1BGJ0" }, { "type": "reactant", "sub_type": "complex_component", "source": "species_10064763", "target": "reaction_10065173" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ0", "target": "species_10064763" }, { "type": "complex_component", "sub_type": "protein_component", "source": "E1BGJ0", "target": "species_10065171" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064753", "target": "species_10064751" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064753", "target": "species_10064749" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10064747", "target": "reaction_10064753" }, { "type": "reactant", "sub_type": "protein_component", "source": "species_10064747", "target": "reaction_10064757" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10064757", "target": "species_10064755" }, { "type": "product", "sub_type": "complex_component", "source": "reaction_10065173", "target": "species_10065171" } ], "pathway_dictionary": { "R-BTA-9020591": { "id": "pathway_10094838", "reactome": "R-BTA-9020591", "name": "Interleukin-12 signaling", "reactions": [ "reaction_10087732", "reaction_10087650", "reaction_10087663", "reaction_10087795", "reaction_10088519" ] }, "R-BTA-112311": { "id": "pathway_10092886", "reactome": "R-BTA-112311", "name": "Neurotransmitter clearance", "reactions": [ "reaction_10046552", "reaction_10038000", "reaction_10045423", "reaction_10046153", "reaction_10088657", "reaction_10046151" ] }, "R-BTA-6791312": { "id": "pathway_10094658", "reactome": "R-BTA-6791312", "name": "TP53 Regulates Transcription of Cell Cycle Genes", "reactions": [ "reaction_10081380", "reaction_10078658", "reaction_10081499", "reaction_10077955", "reaction_10088534", "reaction_10088546", "reaction_10088542", "reaction_10078349" ] }, "R-BTA-196071": { "id": "pathway_10093248", "reactome": "R-BTA-196071", "name": "Metabolism of steroid hormones", "reactions": [ "reaction_10041293", "reaction_10041721", "reaction_10041297", "reaction_10041716", "reaction_10041412", "reaction_10050650", "reaction_10041386", "reaction_10077113", "reaction_10041692", "reaction_10041415", "reaction_10041424", "reaction_10041379", "reaction_10041284", "reaction_10092062", "reaction_10041397", "reaction_10092065", "reaction_10084679", "reaction_10041719", "reaction_10041295", "reaction_10041269", "reaction_10041395", "reaction_10057880", "reaction_10041290", "reaction_10041684", "reaction_10041393", "reaction_10041277", "reaction_10076281", "reaction_10041299", "reaction_10051676" ] }, "R-BTA-71406": { "id": "pathway_10092480", "reactome": "R-BTA-71406", "name": "Pyruvate metabolism and Citric Acid (TCA) cycle", "reactions": [ "reaction_10089782", "reaction_10051980", "reaction_10089721", "reaction_10034240", "reaction_10051973", "reaction_10076468", "reaction_10050446", "reaction_10089808", "reaction_10089728", "reaction_10089795", "reaction_10050437", "reaction_10033868", "reaction_10033671" ] }, "R-BTA-9612973": { "id": "pathway_10094426", "reactome": "R-BTA-9612973", "name": "Autophagy", "reactions": [ "reaction_10070261", "reaction_10073831", "reaction_10074142", "reaction_10074302", "reaction_10090398", "reaction_10087615", "reaction_10074415", "reaction_10073835", "reaction_10074381", "reaction_10074365", "reaction_10074507", "reaction_10074659", "reaction_10070265", "reaction_10070259", "reaction_10088891", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-451306": { "id": "pathway_10093814", "reactome": "R-BTA-451306", "name": "Ionotropic activity of kainate receptors", "reactions": [ "reaction_10050514", "reaction_10050517" ] }, "R-BTA-181430": { "id": "pathway_10093514", "reactome": "R-BTA-181430", "name": "Norepinephrine Neurotransmitter Release Cycle", "reactions": [ "reaction_10045419", "reaction_10045421" ] }, "R-BTA-168176": { "id": "pathway_10093034", "reactome": "R-BTA-168176", "name": "Toll Like Receptor 5 (TLR5) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-3928663": { "id": "pathway_10094396", "reactome": "R-BTA-3928663", "name": "EPHA-mediated growth cone collapse", "reactions": [ "reaction_10069253" ] }, "R-BTA-6788467": { "id": "pathway_10094634", "reactome": "R-BTA-6788467", "name": "IL-6-type cytokine receptor ligand interactions", "reactions": [ "reaction_10077455", "reaction_10077422", "reaction_10077424" ] }, "R-BTA-2172127": { "id": "pathway_10094292", "reactome": "R-BTA-2172127", "name": "DAP12 interactions", "reactions": [ "reaction_10065517", "reaction_10065491" ] }, "R-BTA-190704": { "id": "pathway_10093216", "reactome": "R-BTA-190704", "name": "Oligomerization of connexins into connexons", "reactions": [ "reaction_10040851" ] }, "R-BTA-114608": { "id": "pathway_10093736", "reactome": "R-BTA-114608", "name": "Platelet degranulation ", "reactions": [ "reaction_10050994", "reaction_10051062", "reaction_10050948", "reaction_10050870", "reaction_10051002", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-9013420": { "id": "pathway_10094902", "reactome": "R-BTA-9013420", "name": "RHOU GTPase cycle", "reactions": [ "reaction_10090311", "reaction_10090306" ] }, "R-BTA-446210": { "id": "pathway_10093776", "reactome": "R-BTA-446210", "name": "Synthesis of UDP-N-acetyl-glucosamine", "reactions": [ "reaction_10081497", "reaction_10081490", "reaction_10049778", "reaction_10050153" ] }, "R-BTA-4608870": { "id": "pathway_10094402", "reactome": "R-BTA-4608870", "name": "Asymmetric localization of PCP proteins", "reactions": [ "reaction_10069872", "reaction_10069593", "reaction_10069595" ] }, "R-BTA-211979": { "id": "pathway_10093432", "reactome": "R-BTA-211979", "name": "Eicosanoids", "reactions": [ "reaction_10071909", "reaction_10044480", "reaction_10044151" ] }, "R-BTA-5654719": { "id": "pathway_10094532", "reactome": "R-BTA-5654719", "name": "SHC-mediated cascade:FGFR4", "reactions": [ "reaction_10073044", "reaction_10073037", "reaction_10073041", "reaction_10073047" ] }, "R-BTA-75109": { "id": "pathway_10092672", "reactome": "R-BTA-75109", "name": "Triglyceride biosynthesis", "reactions": [ "reaction_10035795", "reaction_10080887", "reaction_10035838", "reaction_10076847", "reaction_10035829" ] }, "R-BTA-1912408": { "id": "pathway_10094920", "reactome": "R-BTA-1912408", "name": "Pre-NOTCH Transcription and Translation", "reactions": [ "reaction_10090409" ] }, "R-BTA-199992": { "id": "pathway_10093474", "reactome": "R-BTA-199992", "name": "trans-Golgi Network Vesicle Budding", "reactions": [ "reaction_10044826", "reaction_10045538" ] }, "R-BTA-500753": { "id": "pathway_10092584", "reactome": "R-BTA-500753", "name": "Pyrimidine biosynthesis", "reactions": [ "reaction_10034924", "reaction_10034921", "reaction_10034927" ] }, "R-BTA-427589": { "id": "pathway_10093722", "reactome": "R-BTA-427589", "name": "Type II Na+/Pi cotransporters", "reactions": [ "reaction_10048761", "reaction_10048754" ] }, "R-BTA-1474228": { "id": "pathway_10094078", "reactome": "R-BTA-1474228", "name": "Degradation of the extracellular matrix", "reactions": [ "reaction_10059869", "reaction_10064649", "reaction_10076984", "reaction_10059787", "reaction_10059702", "reaction_10059651", "reaction_10059598", "reaction_10059533", "reaction_10064705", "reaction_10087543", "reaction_10059674", "reaction_10059913", "reaction_10059918", "reaction_10058193", "reaction_10058561", "reaction_10065819", "reaction_10065751", "reaction_10087324", "reaction_10059923", "reaction_10068885", "reaction_10059902", "reaction_10059744", "reaction_10060003", "reaction_10059441", "reaction_10059689", "reaction_10059731", "reaction_10059804" ] }, "R-BTA-2029481": { "id": "pathway_10094178", "reactome": "R-BTA-2029481", "name": "FCGR activation", "reactions": [ "reaction_10061174" ] }, "R-BTA-70635": { "id": "pathway_10092488", "reactome": "R-BTA-70635", "name": "Urea cycle", "reactions": [ "reaction_10033690", "reaction_10033770", "reaction_10033706", "reaction_10033697" ] }, "R-BTA-8852135": { "id": "pathway_10094754", "reactome": "R-BTA-8852135", "name": "Protein ubiquitination", "reactions": [ "reaction_10084122", "reaction_10084008", "reaction_10084113", "reaction_10086702", "reaction_10084117", "reaction_10086710" ] }, "R-BTA-375280": { "id": "pathway_10093608", "reactome": "R-BTA-375280", "name": "Amine ligand-binding receptors", "reactions": [ "reaction_10047206", "reaction_10047236", "reaction_10090925", "reaction_10047226", "reaction_10091825", "reaction_10047256", "reaction_10047210", "reaction_10090968", "reaction_10047332", "reaction_10091556", "reaction_10091929", "reaction_10090960", "reaction_10047234", "reaction_10047212", "reaction_10090964", "reaction_10083878", "reaction_10047214", "reaction_10047238", "reaction_10047224", "reaction_10047222" ] }, "R-BTA-2428928": { "id": "pathway_10092648", "reactome": "R-BTA-2428928", "name": "IRS-related events triggered by IGF1R", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-983170": { "id": "pathway_10093378", "reactome": "R-BTA-983170", "name": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC", "reactions": [ "reaction_10055817", "reaction_10054866", "reaction_10055783", "reaction_10055444", "reaction_10055819", "reaction_10055821", "reaction_10055460", "reaction_10043659", "reaction_10087807" ] }, "R-BTA-202040": { "id": "pathway_10093046", "reactome": "R-BTA-202040", "name": "G-protein activation", "reactions": [ "reaction_10039485" ] }, "R-BTA-75108": { "id": "pathway_10092854", "reactome": "R-BTA-75108", "name": "Activation, myristolyation of BID and translocation to mitochondria", "reactions": [ "reaction_10038007", "reaction_10037731", "reaction_10037641", "reaction_10037618" ] }, "R-BTA-444209": { "id": "pathway_10093768", "reactome": "R-BTA-444209", "name": "Free fatty acid receptors", "reactions": [ "reaction_10049585", "reaction_10049615", "reaction_10067360", "reaction_10049617" ] }, "R-BTA-195399": { "id": "pathway_10093262", "reactome": "R-BTA-195399", "name": "VEGF binds to VEGFR leading to receptor dimerization", "reactions": [ "reaction_10041463", "reaction_10041453" ] }, "R-BTA-180292": { "id": "pathway_10093132", "reactome": "R-BTA-180292", "name": "GAB1 signalosome", "reactions": [ "reaction_10040328", "reaction_10040254", "reaction_10040267", "reaction_10040299", "reaction_10040277" ] }, "R-BTA-4641262": { "id": "pathway_10093344", "reactome": "R-BTA-4641262", "name": "Disassembly of the destruction complex and recruitment of AXIN to the membrane", "reactions": [ "reaction_10059152", "reaction_10071320", "reaction_10043129" ] }, "R-BTA-6809371": { "id": "pathway_10094652", "reactome": "R-BTA-6809371", "name": "Formation of the cornified envelope", "reactions": [ "reaction_10083824", "reaction_10083741", "reaction_10083743", "reaction_10083835", "reaction_10077943" ] }, "R-BTA-8857538": { "id": "pathway_10094772", "reactome": "R-BTA-8857538", "name": "PTK6 promotes HIF1A stabilization", "reactions": [ "reaction_10084466" ] }, "R-BTA-9013405": { "id": "pathway_10094890", "reactome": "R-BTA-9013405", "name": "RHOD GTPase cycle", "reactions": [ "reaction_10091916", "reaction_10091884", "reaction_10089985", "reaction_10089972", "reaction_10091902", "reaction_10091878", "reaction_10091896", "reaction_10090009", "reaction_10090011" ] }, "R-BTA-1250347": { "id": "pathway_10094016", "reactome": "R-BTA-1250347", "name": "SHC1 events in ERBB4 signaling", "reactions": [ "reaction_10057177", "reaction_10057175", "reaction_10057191", "reaction_10057188" ] }, "R-BTA-8856688": { "id": "pathway_10094702", "reactome": "R-BTA-8856688", "name": "Golgi-to-ER retrograde transport", "reactions": [ "reaction_10083004", "reaction_10083006", "reaction_10083712", "reaction_10082999" ] }, "R-BTA-446203": { "id": "pathway_10093226", "reactome": "R-BTA-446203", "name": "Asparagine N-linked glycosylation", "reactions": [ "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10077710", "reaction_10053317", "reaction_10076708", "reaction_10076610", "reaction_10069371", "reaction_10077823", "reaction_10056058", "reaction_10054467", "reaction_10082941", "reaction_10069320", "reaction_10049797", "reaction_10069359", "reaction_10054474", "reaction_10049860", "reaction_10076584", "reaction_10053324", "reaction_10069357", "reaction_10049789", "reaction_10081490", "reaction_10049818", "reaction_10054418", "reaction_10049811", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10049867", "reaction_10076696", "reaction_10076635", "reaction_10069368", "reaction_10054438", "reaction_10076586", "reaction_10076736", "reaction_10076706", "reaction_10040933", "reaction_10053337", "reaction_10084373", "reaction_10056061", "reaction_10069373", "reaction_10049858", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10056074", "reaction_10077717", "reaction_10082026", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10053339", "reaction_10076422", "reaction_10054411", "reaction_10077826", "reaction_10076415", "reaction_10049831", "reaction_10083380", "reaction_10049851", "reaction_10049778", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10049844", "reaction_10076778", "reaction_10050153", "reaction_10053331", "reaction_10048958", "reaction_10077816", "reaction_10076698", "reaction_10069382" ] }, "R-BTA-1268020": { "id": "pathway_10094874", "reactome": "R-BTA-1268020", "name": "Mitochondrial protein import", "reactions": [ "reaction_10089391" ] }, "R-BTA-975578": { "id": "pathway_10093926", "reactome": "R-BTA-975578", "name": "Reactions specific to the complex N-glycan synthesis pathway", "reactions": [ "reaction_10076415", "reaction_10077710", "reaction_10077717", "reaction_10076422", "reaction_10054411" ] }, "R-BTA-1236975": { "id": "pathway_10093994", "reactome": "R-BTA-1236975", "name": "Antigen processing-Cross presentation", "reactions": [ "reaction_10056912", "reaction_10056914", "reaction_10056903", "reaction_10056805", "reaction_10056835", "reaction_10056910", "reaction_10084865", "reaction_10084867", "reaction_10056982", "reaction_10087823", "reaction_10057004" ] }, "R-BTA-196836": { "id": "pathway_10093310", "reactome": "R-BTA-196836", "name": "Vitamin C (ascorbate) metabolism", "reactions": [ "reaction_10041955", "reaction_10041962", "reaction_10041975" ] }, "R-BTA-8849468": { "id": "pathway_10094740", "reactome": "R-BTA-8849468", "name": "PTK6 Regulates Proteins Involved in RNA Processing", "reactions": [ "reaction_10083676", "reaction_10083656", "reaction_10083664", "reaction_10083672" ] }, "R-BTA-140180": { "id": "pathway_10092866", "reactome": "R-BTA-140180", "name": "COX reactions", "reactions": [ "reaction_10037751", "reaction_10037748" ] }, "R-BTA-8978868": { "id": "pathway_10092526", "reactome": "R-BTA-8978868", "name": "Fatty acid metabolism", "reactions": [ "reaction_10064516", "reaction_10082880", "reaction_10051252", "reaction_10036220", "reaction_10065216", "reaction_10046992", "reaction_10064565", "reaction_10042860", "reaction_10086336", "reaction_10036038", "reaction_10063430", "reaction_10063442", "reaction_10064506", "reaction_10036029", "reaction_10036040", "reaction_10063444", "reaction_10044657", "reaction_10063425", "reaction_10063428", "reaction_10036218", "reaction_10064442", "reaction_10063570", "reaction_10065225", "reaction_10046984", "reaction_10042961", "reaction_10064521", "reaction_10047001", "reaction_10085185", "reaction_10047058", "reaction_10036021", "reaction_10033912", "reaction_10064465", "reaction_10033896", "reaction_10075607", "reaction_10065213", "reaction_10064567", "reaction_10064482", "reaction_10077784", "reaction_10063420", "reaction_10064452", "reaction_10086403", "reaction_10047042", "reaction_10064479", "reaction_10063440", "reaction_10064546", "reaction_10074353", "reaction_10077835", "reaction_10037751", "reaction_10065210", "reaction_10047044", "reaction_10064554", "reaction_10065223", "reaction_10083389", "reaction_10036025", "reaction_10044599", "reaction_10064474", "reaction_10054592", "reaction_10037748", "reaction_10064578", "reaction_10036042", "reaction_10046989", "reaction_10036664", "reaction_10063452", "reaction_10076382", "reaction_10063413", "reaction_10036027", "reaction_10063446", "reaction_10047056", "reaction_10063437", "reaction_10036012", "reaction_10064445", "reaction_10047033", "reaction_10033889", "reaction_10042897", "reaction_10047053", "reaction_10076806", "reaction_10036023", "reaction_10064581", "reaction_10064503", "reaction_10063573", "reaction_10064534", "reaction_10063450", "reaction_10077001", "reaction_10064531", "reaction_10064526", "reaction_10075576", "reaction_10064511", "reaction_10044151", "reaction_10051261", "reaction_10075631", "reaction_10082889", "reaction_10063454", "reaction_10063456", "reaction_10063448" ] }, "R-BTA-389599": { "id": "pathway_10093588", "reactome": "R-BTA-389599", "name": "Alpha-oxidation of phytanate", "reactions": [ "reaction_10047001", "reaction_10046992", "reaction_10082889", "reaction_10046984", "reaction_10046989" ] }, "R-BTA-352230": { "id": "pathway_10093482", "reactome": "R-BTA-352230", "name": "Amino acid transport across the plasma membrane", "reactions": [ "reaction_10045473", "reaction_10045480", "reaction_10044964", "reaction_10045494", "reaction_10085384", "reaction_10044934", "reaction_10088905", "reaction_10044941", "reaction_10044985", "reaction_10045487", "reaction_10045501", "reaction_10044971", "reaction_10044962", "reaction_10044948", "reaction_10044978", "reaction_10044955" ] }, "R-BTA-187042": { "id": "pathway_10093012", "reactome": "R-BTA-187042", "name": "TRKA activation by NGF", "reactions": [ "reaction_10039270", "reaction_10039272", "reaction_10040684" ] }, "R-BTA-381426": { "id": "pathway_10093550", "reactome": "R-BTA-381426", "name": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)", "reactions": [ "reaction_10088473", "reaction_10046621" ] }, "R-BTA-2559584": { "id": "pathway_10094386", "reactome": "R-BTA-2559584", "name": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)", "reactions": [ "reaction_10068959" ] }, "R-BTA-9663891": { "id": "pathway_10094422", "reactome": "R-BTA-9663891", "name": "Selective autophagy", "reactions": [ "reaction_10070261", "reaction_10087615", "reaction_10088891", "reaction_10070265", "reaction_10070259", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-1227986": { "id": "pathway_10094014", "reactome": "R-BTA-1227986", "name": "Signaling by ERBB2", "reactions": [ "reaction_10057740", "reaction_10061480", "reaction_10057139", "reaction_10077601", "reaction_10084849", "reaction_10077605", "reaction_10057735", "reaction_10057700", "reaction_10057695", "reaction_10057742", "reaction_10086415", "reaction_10057744", "reaction_10057712", "reaction_10083477", "reaction_10057719", "reaction_10061469", "reaction_10061458", "reaction_10083483", "reaction_10061492", "reaction_10057692" ] }, "R-BTA-196843": { "id": "pathway_10093288", "reactome": "R-BTA-196843", "name": "Vitamin B2 (riboflavin) metabolism", "reactions": [ "reaction_10041790", "reaction_10041772", "reaction_10041781", "reaction_10066602", "reaction_10041799" ] }, "R-BTA-449147": { "id": "pathway_10093066", "reactome": "R-BTA-449147", "name": "Signaling by Interleukins", "reactions": [ "reaction_10051194", "reaction_10056201", "reaction_10051936", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10052254", "reaction_10089466", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10089691", "reaction_10050231", "reaction_10042826", "reaction_10051966", "reaction_10050011", "reaction_10089329", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10049970", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10056110", "reaction_10089431", "reaction_10089540", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10090031", "reaction_10089536", "reaction_10089251", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10090027", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10050256", "reaction_10056194", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10089689", "reaction_10043867", "reaction_10077723", "reaction_10056132", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10077424", "reaction_10056207", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10089542", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10087766", "reaction_10049928", "reaction_10050428", "reaction_10083522", "reaction_10039508", "reaction_10050420", "reaction_10087650", "reaction_10052327", "reaction_10089736", "reaction_10051949", "reaction_10089269", "reaction_10089597", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10056168", "reaction_10087793", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10085017", "reaction_10051954", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-157118": { "id": "pathway_10094186", "reactome": "R-BTA-157118", "name": "Signaling by NOTCH", "reactions": [ "reaction_10090409", "reaction_10090834", "reaction_10061449" ] }, "R-BTA-389661": { "id": "pathway_10093592", "reactome": "R-BTA-389661", "name": "Glyoxylate metabolism and glycine degradation", "reactions": [ "reaction_10078366", "reaction_10076450", "reaction_10078402", "reaction_10076441", "reaction_10076459", "reaction_10078393", "reaction_10047019", "reaction_10078701", "reaction_10077458", "reaction_10052056", "reaction_10047022" ] }, "R-BTA-877300": { "id": "pathway_10093858", "reactome": "R-BTA-877300", "name": "Interferon gamma signaling", "reactions": [ "reaction_10051771", "reaction_10051774", "reaction_10051818", "reaction_10051780", "reaction_10051786", "reaction_10052067", "reaction_10051762", "reaction_10091723", "reaction_10051792", "reaction_10051696", "reaction_10051737", "reaction_10055967", "reaction_10051748" ] }, "R-BTA-388844": { "id": "pathway_10093576", "reactome": "R-BTA-388844", "name": "Receptor-type tyrosine-protein phosphatases", "reactions": [ "reaction_10078674", "reaction_10078682", "reaction_10046868", "reaction_10078566" ] }, "R-BTA-390918": { "id": "pathway_10093590", "reactome": "R-BTA-390918", "name": "Peroxisomal lipid metabolism", "reactions": [ "reaction_10047001", "reaction_10054592", "reaction_10047044", "reaction_10046992", "reaction_10082889", "reaction_10082880", "reaction_10046984", "reaction_10047058", "reaction_10075576", "reaction_10047056", "reaction_10047053", "reaction_10077784", "reaction_10046989", "reaction_10047042", "reaction_10047033", "reaction_10077835" ] }, "R-BTA-380612": { "id": "pathway_10092882", "reactome": "R-BTA-380612", "name": "Metabolism of serotonin", "reactions": [ "reaction_10046552", "reaction_10038000" ] }, "R-BTA-73843": { "id": "pathway_10092588", "reactome": "R-BTA-73843", "name": "5-Phosphoribose 1-diphosphate biosynthesis", "reactions": [ "reaction_10034944", "reaction_10036903" ] }, "R-BTA-2424491": { "id": "pathway_10094290", "reactome": "R-BTA-2424491", "name": "DAP12 signaling", "reactions": [ "reaction_10065517", "reaction_10065491" ] }, "R-BTA-1482839": { "id": "pathway_10094104", "reactome": "R-BTA-1482839", "name": "Acyl chain remodelling of PE", "reactions": [ "reaction_10076792", "reaction_10059002", "reaction_10084526", "reaction_10059004", "reaction_10058885", "reaction_10059853", "reaction_10058899", "reaction_10058980" ] }, "R-BTA-389948": { "id": "pathway_10093580", "reactome": "R-BTA-389948", "name": "PD-1 signaling", "reactions": [ "reaction_10046888", "reaction_10091743" ] }, "R-BTA-2161522": { "id": "pathway_10094236", "reactome": "R-BTA-2161522", "name": "Abacavir transport and metabolism", "reactions": [ "reaction_10064439", "reaction_10064584" ] }, "R-BTA-2428924": { "id": "pathway_10092650", "reactome": "R-BTA-2428924", "name": "IGF1R signaling cascade", "reactions": [ "reaction_10075063", "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-8941856": { "id": "pathway_10094804", "reactome": "R-BTA-8941856", "name": "RUNX3 regulates NOTCH signaling", "reactions": [ "reaction_10086241" ] }, "R-BTA-5654708": { "id": "pathway_10094512", "reactome": "R-BTA-5654708", "name": "Downstream signaling of activated FGFR3", "reactions": [ "reaction_10073014", "reaction_10072946", "reaction_10073147", "reaction_10073021", "reaction_10073011", "reaction_10087376", "reaction_10073234", "reaction_10073019", "reaction_10072944", "reaction_10072913", "reaction_10073152", "reaction_10073159", "reaction_10073156", "reaction_10073145", "reaction_10073140" ] }, "R-BTA-2022928": { "id": "pathway_10093854", "reactome": "R-BTA-2022928", "name": "HS-GAG biosynthesis", "reactions": [ "reaction_10063010", "reaction_10062984", "reaction_10063216", "reaction_10063603", "reaction_10063586", "reaction_10063610", "reaction_10051589", "reaction_10063633" ] }, "R-BTA-8854521": { "id": "pathway_10094758", "reactome": "R-BTA-8854521", "name": "Interaction between PHLDA1 and AURKA", "reactions": [ "reaction_10084090", "reaction_10084096" ] }, "R-BTA-5689901": { "id": "pathway_10094624", "reactome": "R-BTA-5689901", "name": "Metalloprotease DUBs", "reactions": [ "reaction_10076119", "reaction_10076112" ] }, "R-BTA-162582": { "id": "pathway_10092534", "reactome": "R-BTA-162582", "name": "Signal Transduction", "reactions": [ "reaction_10047236", "reaction_10073796", "reaction_10040769", "reaction_10090087", "reaction_10073716", "reaction_10041917", "reaction_10047362", "reaction_10047979", "reaction_10041463", "reaction_10047398", "reaction_10091158", "reaction_10063374", "reaction_10047334", "reaction_10091156", "reaction_10063319", "reaction_10073021", "reaction_10090198", "reaction_10086575", "reaction_10067364", "reaction_10057318", "reaction_10068933", "reaction_10056781", "reaction_10068939", "reaction_10047851", "reaction_10091576", "reaction_10063534", "reaction_10068086", "reaction_10063843", "reaction_10083588", "reaction_10069651", "reaction_10083632", "reaction_10090675", "reaction_10037549", "reaction_10072123", "reaction_10037022", "reaction_10083878", "reaction_10083629", "reaction_10091118", "reaction_10060448", "reaction_10083880", "reaction_10075223", "reaction_10043488", "reaction_10091267", "reaction_10040761", "reaction_10061492", "reaction_10057236", "reaction_10090330", "reaction_10072946", "reaction_10083646", "reaction_10040489", "reaction_10072715", "reaction_10083695", "reaction_10088940", "reaction_10074137", "reaction_10040258", "reaction_10047210", "reaction_10047256", "reaction_10041869", "reaction_10046572", "reaction_10091751", "reaction_10049699", "reaction_10071508", "reaction_10091556", "reaction_10046919", "reaction_10073122", "reaction_10040326", "reaction_10076193", "reaction_10040696", "reaction_10046953", "reaction_10047374", "reaction_10058474", "reaction_10073044", "reaction_10089947", "reaction_10091271", "reaction_10071534", "reaction_10068839", "reaction_10089011", "reaction_10044465", "reaction_10046915", "reaction_10074879", "reaction_10067204", "reaction_10040773", "reaction_10084080", "reaction_10074184", "reaction_10064910", "reaction_10040458", "reaction_10045168", "reaction_10072685", "reaction_10046534", "reaction_10047857", "reaction_10045332", "reaction_10090555", "reaction_10040782", "reaction_10073041", "reaction_10063317", "reaction_10048214", "reaction_10072720", "reaction_10091458", "reaction_10035527", "reaction_10040317", "reaction_10047226", "reaction_10072929", "reaction_10071397", "reaction_10084016", "reaction_10071407", "reaction_10064933", "reaction_10046660", "reaction_10067698", "reaction_10072397", "reaction_10089222", "reaction_10072976", "reaction_10071506", "reaction_10046677", "reaction_10039674", "reaction_10091115", "reaction_10072900", "reaction_10036146", "reaction_10046729", "reaction_10077601", "reaction_10041583", "reaction_10072677", "reaction_10091896", "reaction_10057744", "reaction_10040794", "reaction_10068837", "reaction_10046763", "reaction_10083664", "reaction_10063568", "reaction_10071678", "reaction_10073246", "reaction_10090964", "reaction_10073177", "reaction_10075097", "reaction_10063550", "reaction_10063556", "reaction_10048632", "reaction_10089952", "reaction_10057323", "reaction_10039160", "reaction_10074176", "reaction_10069459", "reaction_10049645", "reaction_10073549", "reaction_10047866", "reaction_10068073", "reaction_10039653", "reaction_10073090", "reaction_10047468", "reaction_10090501", "reaction_10069645", "reaction_10053333", "reaction_10063554", "reaction_10057850", "reaction_10090009", "reaction_10075262", "reaction_10091916", "reaction_10090666", "reaction_10036570", "reaction_10089203", "reaction_10069535", "reaction_10092203", "reaction_10072515", "reaction_10049657", "reaction_10073503", "reaction_10066994", "reaction_10048180", "reaction_10087367", "reaction_10040684", "reaction_10046735", "reaction_10072606", "reaction_10073755", "reaction_10074088", "reaction_10041604", "reaction_10091689", "reaction_10075260", "reaction_10088493", "reaction_10072628", "reaction_10071648", "reaction_10073930", "reaction_10092364", "reaction_10090203", "reaction_10074156", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10091864", "reaction_10073182", "reaction_10073921", "reaction_10039651", "reaction_10073559", "reaction_10040860", "reaction_10036616", "reaction_10057302", "reaction_10040286", "reaction_10040393", "reaction_10071504", "reaction_10045384", "reaction_10037045", "reaction_10091812", "reaction_10057139", "reaction_10073904", "reaction_10039736", "reaction_10071356", "reaction_10073234", "reaction_10092205", "reaction_10044470", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10074231", "reaction_10045268", "reaction_10090949", "reaction_10067350", "reaction_10083638", "reaction_10063353", "reaction_10073525", "reaction_10069593", "reaction_10069299", "reaction_10073102", "reaction_10045350", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10073569", "reaction_10044211", "reaction_10067200", "reaction_10039485", "reaction_10072937", "reaction_10074038", "reaction_10091527", "reaction_10073201", "reaction_10047354", "reaction_10045324", "reaction_10040331", "reaction_10088942", "reaction_10039272", "reaction_10067124", "reaction_10091180", "reaction_10090306", "reaction_10072939", "reaction_10040289", "reaction_10056354", "reaction_10073106", "reaction_10083697", "reaction_10073113", "reaction_10048208", "reaction_10045072", "reaction_10039601", "reaction_10043778", "reaction_10091506", "reaction_10035536", "reaction_10064919", "reaction_10073932", "reaction_10047364", "reaction_10069607", "reaction_10049279", "reaction_10057262", "reaction_10090956", "reaction_10072433", "reaction_10039127", "reaction_10073133", "reaction_10057700", "reaction_10083656", "reaction_10073228", "reaction_10092382", "reaction_10057704", "reaction_10047212", "reaction_10049506", "reaction_10041950", "reaction_10040369", "reaction_10057857", "reaction_10041453", "reaction_10071673", "reaction_10091151", "reaction_10069882", "reaction_10049683", "reaction_10089860", "reaction_10073222", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10090452", "reaction_10042976", "reaction_10051656", "reaction_10049894", "reaction_10090103", "reaction_10046588", "reaction_10091921", "reaction_10067694", "reaction_10070628", "reaction_10045292", "reaction_10091902", "reaction_10092002", "reaction_10073853", "reaction_10047366", "reaction_10091832", "reaction_10046666", "reaction_10073004", "reaction_10057177", "reaction_10090311", "reaction_10043744", "reaction_10077605", "reaction_10083652", "reaction_10076840", "reaction_10063544", "reaction_10083933", "reaction_10036607", "reaction_10047234", "reaction_10073731", "reaction_10037004", "reaction_10049520", "reaction_10039592", "reaction_10057719", "reaction_10073940", "reaction_10049478", "reaction_10051667", "reaction_10065099", "reaction_10048660", "reaction_10040310", "reaction_10041863", "reaction_10073851", "reaction_10039180", "reaction_10071556", "reaction_10090563", "reaction_10073129", "reaction_10090145", "reaction_10046917", "reaction_10043315", "reaction_10073083", "reaction_10040299", "reaction_10067879", "reaction_10040785", "reaction_10091275", "reaction_10040570", "reaction_10063382", "reaction_10048178", "reaction_10057284", "reaction_10071320", "reaction_10084723", "reaction_10090559", "reaction_10083935", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10047483", "reaction_10075916", "reaction_10047956", "reaction_10040704", "reaction_10057742", "reaction_10089214", "reaction_10067358", "reaction_10090369", "reaction_10036981", "reaction_10041647", "reaction_10074050", "reaction_10073942", "reaction_10089890", "reaction_10091570", "reaction_10070657", "reaction_10048282", "reaction_10090266", "reaction_10067696", "reaction_10057272", "reaction_10041606", "reaction_10040791", "reaction_10047222", "reaction_10092020", "reaction_10091247", "reaction_10045106", "reaction_10087531", "reaction_10074195", "reaction_10067128", "reaction_10037037", "reaction_10090994", "reaction_10073147", "reaction_10057327", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10090119", "reaction_10067360", "reaction_10039676", "reaction_10075239", "reaction_10041637", "reaction_10040229", "reaction_10040744", "reaction_10045180", "reaction_10040779", "reaction_10090082", "reaction_10090339", "reaction_10091741", "reaction_10048326", "reaction_10089224", "reaction_10049570", "reaction_10057862", "reaction_10048587", "reaction_10072902", "reaction_10039581", "reaction_10046149", "reaction_10084849", "reaction_10070676", "reaction_10091884", "reaction_10039697", "reaction_10063338", "reaction_10053335", "reaction_10049585", "reaction_10073115", "reaction_10072999", "reaction_10039059", "reaction_10086415", "reaction_10090246", "reaction_10073001", "reaction_10040447", "reaction_10063346", "reaction_10071668", "reaction_10089841", "reaction_10040421", "reaction_10083565", "reaction_10048370", "reaction_10089149", "reaction_10047214", "reaction_10091572", "reaction_10057184", "reaction_10045280", "reaction_10074221", "reaction_10091169", "reaction_10075253", "reaction_10073326", "reaction_10057191", "reaction_10056356", "reaction_10073507", "reaction_10057286", "reaction_10092026", "reaction_10073208", "reaction_10048248", "reaction_10090089", "reaction_10047396", "reaction_10047498", "reaction_10049617", "reaction_10035726", "reaction_10089972", "reaction_10061449", "reaction_10040432", "reaction_10069876", "reaction_10047853", "reaction_10074238", "reaction_10090349", "reaction_10073557", "reaction_10087597", "reaction_10090409", "reaction_10047378", "reaction_10057735", "reaction_10051907", "reaction_10073011", "reaction_10065227", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10039209", "reaction_10069456", "reaction_10071526", "reaction_10033926", "reaction_10090098", "reaction_10061458", "reaction_10083483", "reaction_10073071", "reaction_10067362", "reaction_10043877", "reaction_10043832", "reaction_10057337", "reaction_10047206", "reaction_10072138", "reaction_10069448", "reaction_10090925", "reaction_10091878", "reaction_10090091", "reaction_10041649", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10074129", "reaction_10057151", "reaction_10046731", "reaction_10057872", "reaction_10083951", "reaction_10036148", "reaction_10092380", "reaction_10047947", "reaction_10041851", "reaction_10039671", "reaction_10090727", "reaction_10068707", "reaction_10037330", "reaction_10090971", "reaction_10048304", "reaction_10071659", "reaction_10069647", "reaction_10040303", "reaction_10075906", "reaction_10073547", "reaction_10073175", "reaction_10092392", "reaction_10084542", "reaction_10072944", "reaction_10040753", "reaction_10038450", "reaction_10092022", "reaction_10072225", "reaction_10072933", "reaction_10090115", "reaction_10090712", "reaction_10071262", "reaction_10041640", "reaction_10071330", "reaction_10060556", "reaction_10045362", "reaction_10057867", "reaction_10068095", "reaction_10092031", "reaction_10073561", "reaction_10091175", "reaction_10073231", "reaction_10071691", "reaction_10073244", "reaction_10076198", "reaction_10058480", "reaction_10073028", "reaction_10073159", "reaction_10072927", "reaction_10073215", "reaction_10049615", "reaction_10073014", "reaction_10091595", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10039667", "reaction_10040323", "reaction_10049643", "reaction_10073127", "reaction_10063342", "reaction_10073087", "reaction_10047332", "reaction_10038918", "reaction_10090567", "reaction_10047862", "reaction_10047552", "reaction_10073842", "reaction_10083676", "reaction_10036959", "reaction_10073242", "reaction_10091479", "reaction_10086565", "reaction_10073166", "reaction_10039658", "reaction_10074146", "reaction_10043753", "reaction_10090960", "reaction_10047870", "reaction_10047868", "reaction_10075256", "reaction_10057264", "reaction_10090077", "reaction_10049681", "reaction_10073152", "reaction_10089197", "reaction_10045016", "reaction_10035507", "reaction_10083558", "reaction_10046583", "reaction_10073140", "reaction_10048170", "reaction_10057712", "reaction_10040460", "reaction_10072931", "reaction_10092370", "reaction_10086662", "reaction_10046773", "reaction_10036590", "reaction_10059152", "reaction_10072913", "reaction_10047238", "reaction_10092055", "reaction_10073047", "reaction_10067895", "reaction_10039711", "reaction_10043129", "reaction_10057188", "reaction_10081580", "reaction_10089937", "reaction_10072979", "reaction_10072220", "reaction_10089211", "reaction_10089207", "reaction_10041333", "reaction_10069896", "reaction_10051217", "reaction_10043311", "reaction_10072993", "reaction_10091580", "reaction_10040451", "reaction_10039200", "reaction_10091994", "reaction_10090125", "reaction_10048174", "reaction_10040462", "reaction_10063380", "reaction_10053213", "reaction_10042860", "reaction_10090968", "reaction_10075063", "reaction_10073077", "reaction_10090428", "reaction_10075205", "reaction_10041629", "reaction_10083707", "reaction_10057329", "reaction_10072154", "reaction_10083726", "reaction_10057252", "reaction_10053082", "reaction_10091548", "reaction_10047860", "reaction_10091534", "reaction_10076743", "reaction_10087373", "reaction_10091037", "reaction_10073577", "reaction_10069872", "reaction_10073031", "reaction_10040277", "reaction_10073872", "reaction_10071524", "reaction_10048172", "reaction_10047394", "reaction_10091260", "reaction_10089985", "reaction_10071541", "reaction_10083690", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043461", "reaction_10075065", "reaction_10090722", "reaction_10073108", "reaction_10084702", "reaction_10089228", "reaction_10069664", "reaction_10073225", "reaction_10076229", "reaction_10048270", "reaction_10049639", "reaction_10039270", "reaction_10057314", "reaction_10058478", "reaction_10070651", "reaction_10089761", "reaction_10091929", "reaction_10070645", "reaction_10047823", "reaction_10083581", "reaction_10083672", "reaction_10091568", "reaction_10057854", "reaction_10048176", "reaction_10057695", "reaction_10039690", "reaction_10072909", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10037964", "reaction_10090954", "reaction_10073844", "reaction_10087370", "reaction_10068923", "reaction_10080870", "reaction_10083477", "reaction_10073328", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10083622", "reaction_10040453", "reaction_10047989", "reaction_10045156", "reaction_10063305", "reaction_10045094", "reaction_10075218", "reaction_10040495", "reaction_10044472", "reaction_10068078", "reaction_10057740", "reaction_10068704", "reaction_10090571", "reaction_10049637", "reaction_10073240", "reaction_10073806", "reaction_10073145", "reaction_10090456", "reaction_10057175", "reaction_10063849", "reaction_10043739", "reaction_10068088", "reaction_10049659", "reaction_10088496", "reaction_10091763", "reaction_10070931", "reaction_10073199", "reaction_10063408", "reaction_10072081", "reaction_10070594", "reaction_10040386", "reaction_10083729", "reaction_10092394", "reaction_10075251", "reaction_10039155", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10072630", "reaction_10073037", "reaction_10084067", "reaction_10073237", "reaction_10089217", "reaction_10040720", "reaction_10083684", "reaction_10041470", "reaction_10073136", "reaction_10067202", "reaction_10067908", "reaction_10039664", "reaction_10057692", "reaction_10057845", "reaction_10091529", "reaction_10089888", "reaction_10045196", "reaction_10067348", "reaction_10061480", "reaction_10091515", "reaction_10046733", "reaction_10083487", "reaction_10090011", "reaction_10091490", "reaction_10072920", "reaction_10070589", "reaction_10037332", "reaction_10078536", "reaction_10089930", "reaction_10041657", "reaction_10092208", "reaction_10069595", "reaction_10070615", "reaction_10057298", "reaction_10084466", "reaction_10073917", "reaction_10047380", "reaction_10090834", "reaction_10063329", "reaction_10073493", "reaction_10074148", "reaction_10072199", "reaction_10057166", "reaction_10073097", "reaction_10092314", "reaction_10047224", "reaction_10073156", "reaction_10072713" ] }, "R-BTA-193144": { "id": "pathway_10093250", "reactome": "R-BTA-193144", "name": "Estrogen biosynthesis", "reactions": [ "reaction_10041277", "reaction_10077113", "reaction_10084679", "reaction_10076281", "reaction_10041299", "reaction_10051676" ] }, "R-BTA-381119": { "id": "pathway_10093548", "reactome": "R-BTA-381119", "name": "Unfolded Protein Response (UPR)", "reactions": [ "reaction_10046602", "reaction_10046604", "reaction_10085865" ] }, "R-BTA-380108": { "id": "pathway_10093498", "reactome": "R-BTA-380108", "name": "Chemokine receptors bind chemokines", "reactions": [ "reaction_10045072", "reaction_10045106", "reaction_10049520", "reaction_10049570", "reaction_10049639", "reaction_10045168", "reaction_10045196", "reaction_10083880", "reaction_10045156", "reaction_10045094", "reaction_10067358", "reaction_10045180", "reaction_10045280", "reaction_10045268" ] }, "R-BTA-2022857": { "id": "pathway_10094138", "reactome": "R-BTA-2022857", "name": "Keratan sulfate degradation", "reactions": [ "reaction_10063510", "reaction_10091293", "reaction_10060293", "reaction_10060285", "reaction_10060295" ] }, "R-BTA-2142816": { "id": "pathway_10094244", "reactome": "R-BTA-2142816", "name": "Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)", "reactions": [ "reaction_10064511", "reaction_10064516", "reaction_10064531" ] }, "R-BTA-140837": { "id": "pathway_10092912", "reactome": "R-BTA-140837", "name": "Intrinsic Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10091671", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10038205", "reaction_10090718", "reaction_10071946", "reaction_10038221", "reaction_10090185", "reaction_10091546", "reaction_10038166", "reaction_10038201", "reaction_10038213" ] }, "R-BTA-73864": { "id": "pathway_10092602", "reactome": "R-BTA-73864", "name": "RNA Polymerase I Transcription", "reactions": [ "reaction_10035301", "reaction_10035254" ] }, "R-BTA-392499": { "id": "pathway_10092572", "reactome": "R-BTA-392499", "name": "Metabolism of proteins", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10034383", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10074707", "reaction_10081490", "reaction_10050169", "reaction_10049811", "reaction_10048461", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10091124", "reaction_10043698", "reaction_10088807", "reaction_10088922", "reaction_10069329", "reaction_10069498", "reaction_10034224", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10046602", "reaction_10048465", "reaction_10082038", "reaction_10074857", "reaction_10083380", "reaction_10087883", "reaction_10034387", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10075023", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10038107", "reaction_10074833", "reaction_10077363", "reaction_10091120", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10075095", "reaction_10077034", "reaction_10048761", "reaction_10091056", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10075125", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10034905", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10049392", "reaction_10034855", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10083808", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10046723", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10048429", "reaction_10076119", "reaction_10048003", "reaction_10056074", "reaction_10076773", "reaction_10045744", "reaction_10077331", "reaction_10082045", "reaction_10077947", "reaction_10049831", "reaction_10038408", "reaction_10074686", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10049385", "reaction_10074863", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10085865", "reaction_10083231", "reaction_10076610", "reaction_10038082", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10075105", "reaction_10049789", "reaction_10046621", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10048380", "reaction_10076586", "reaction_10040933", "reaction_10048407", "reaction_10060894", "reaction_10046604", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10034365", "reaction_10088734", "reaction_10045696", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10075086", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10045736", "reaction_10075084", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10075019", "reaction_10048958", "reaction_10087848", "reaction_10074869", "reaction_10045694" ] }, "R-BTA-5633008": { "id": "pathway_10094670", "reactome": "R-BTA-5633008", "name": "TP53 Regulates Transcription of Cell Death Genes", "reactions": [ "reaction_10080738", "reaction_10081291", "reaction_10081278", "reaction_10081274", "reaction_10081326", "reaction_10081305", "reaction_10081286", "reaction_10081323", "reaction_10080789", "reaction_10080457", "reaction_10081293" ] }, "R-BTA-204005": { "id": "pathway_10093372", "reactome": "R-BTA-204005", "name": "COPII-mediated vesicle transport", "reactions": [ "reaction_10083380", "reaction_10043649", "reaction_10076775", "reaction_10076610", "reaction_10076778", "reaction_10076635", "reaction_10076736", "reaction_10083377", "reaction_10076584", "reaction_10076698" ] }, "R-BTA-1234174": { "id": "pathway_10093986", "reactome": "R-BTA-1234174", "name": "Cellular response to hypoxia", "reactions": [ "reaction_10056688", "reaction_10056719", "reaction_10056754", "reaction_10056757", "reaction_10056759", "reaction_10056761", "reaction_10056702", "reaction_10056679", "reaction_10056737" ] }, "R-BTA-4086398": { "id": "pathway_10094398", "reactome": "R-BTA-4086398", "name": "Ca2+ pathway", "reactions": [ "reaction_10069456", "reaction_10069459", "reaction_10069448" ] }, "R-BTA-9013423": { "id": "pathway_10094904", "reactome": "R-BTA-9013423", "name": "RAC3 GTPase cycle", "reactions": [ "reaction_10092394", "reaction_10090339", "reaction_10090330", "reaction_10092392", "reaction_10090349" ] }, "R-BTA-380095": { "id": "pathway_10093564", "reactome": "R-BTA-380095", "name": "Tachykinin receptors bind tachykinins", "reactions": [ "reaction_10046729" ] }, "R-BTA-6811436": { "id": "pathway_10094744", "reactome": "R-BTA-6811436", "name": "COPI-independent Golgi-to-ER retrograde traffic", "reactions": [ "reaction_10083712" ] }, "R-BTA-350562": { "id": "pathway_10093470", "reactome": "R-BTA-350562", "name": "Regulation of ornithine decarboxylase (ODC)", "reactions": [ "reaction_10044794", "reaction_10044784", "reaction_10044776" ] }, "R-BTA-392517": { "id": "pathway_10093490", "reactome": "R-BTA-392517", "name": "Rap1 signalling", "reactions": [ "reaction_10052471", "reaction_10053213", "reaction_10052466", "reaction_10047536", "reaction_10045016", "reaction_10047519" ] }, "R-BTA-5576893": { "id": "pathway_10094458", "reactome": "R-BTA-5576893", "name": "Phase 2 - plateau phase", "reactions": [ "reaction_10071800" ] }, "R-BTA-428157": { "id": "pathway_10093728", "reactome": "R-BTA-428157", "name": "Sphingolipid metabolism", "reactions": [ "reaction_10060021", "reaction_10049182", "reaction_10048860", "reaction_10049154", "reaction_10060041", "reaction_10076389", "reaction_10071483", "reaction_10082058", "reaction_10049163", "reaction_10048986", "reaction_10048910", "reaction_10060109", "reaction_10049161", "reaction_10049121", "reaction_10059961", "reaction_10091936", "reaction_10048995", "reaction_10049116", "reaction_10059991", "reaction_10060316", "reaction_10048889", "reaction_10049141", "reaction_10060012", "reaction_10049004", "reaction_10059977", "reaction_10049189", "reaction_10059984", "reaction_10059951", "reaction_10091941", "reaction_10060302", "reaction_10076151", "reaction_10048988", "reaction_10059954", "reaction_10076833", "reaction_10059944", "reaction_10084410", "reaction_10048903", "reaction_10049007", "reaction_10048882", "reaction_10049143", "reaction_10048978", "reaction_10048917", "reaction_10059968", "reaction_10048896", "reaction_10071497", "reaction_10060309" ] }, "R-BTA-6803207": { "id": "pathway_10094680", "reactome": "R-BTA-6803207", "name": "TP53 Regulates Transcription of Caspase Activators and Caspases", "reactions": [ "reaction_10081291", "reaction_10081278", "reaction_10081274", "reaction_10081286", "reaction_10081293" ] }, "R-BTA-209905": { "id": "pathway_10093414", "reactome": "R-BTA-209905", "name": "Catecholamine biosynthesis", "reactions": [ "reaction_10043933" ] }, "R-BTA-5662702": { "id": "pathway_10094554", "reactome": "R-BTA-5662702", "name": "Melanin biosynthesis", "reactions": [ "reaction_10073477" ] }, "R-BTA-211935": { "id": "pathway_10092698", "reactome": "R-BTA-211935", "name": "Fatty acids", "reactions": [ "reaction_10044260", "reaction_10035958", "reaction_10044195", "reaction_10044216" ] }, "R-BTA-9013409": { "id": "pathway_10094898", "reactome": "R-BTA-9013409", "name": "RHOJ GTPase cycle", "reactions": [ "reaction_10090198", "reaction_10090203" ] }, "R-BTA-201451": { "id": "pathway_10093334", "reactome": "R-BTA-201451", "name": "Signaling by BMP", "reactions": [ "reaction_10042976", "reaction_10043311", "reaction_10084542" ] }, "R-BTA-512988": { "id": "pathway_10093824", "reactome": "R-BTA-512988", "name": "Interleukin-3, Interleukin-5 and GM-CSF signaling", "reactions": [ "reaction_10051966", "reaction_10052735", "reaction_10051949", "reaction_10051962", "reaction_10052343", "reaction_10050619", "reaction_10050623", "reaction_10051936", "reaction_10052321", "reaction_10052240", "reaction_10051954", "reaction_10052294", "reaction_10052254", "reaction_10052325", "reaction_10052337", "reaction_10052323", "reaction_10052302", "reaction_10052327" ] }, "R-BTA-425561": { "id": "pathway_10093702", "reactome": "R-BTA-425561", "name": "Sodium/Calcium exchangers", "reactions": [ "reaction_10072522", "reaction_10048526", "reaction_10048504", "reaction_10048533" ] }, "R-BTA-6807878": { "id": "pathway_10094692", "reactome": "R-BTA-6807878", "name": "COPI-mediated anterograde transport", "reactions": [ "reaction_10082038", "reaction_10082045", "reaction_10082026" ] }, "R-BTA-200425": { "id": "pathway_10093328", "reactome": "R-BTA-200425", "name": "Carnitine metabolism", "reactions": [ "reaction_10085185", "reaction_10042897", "reaction_10042860" ] }, "R-BTA-975576": { "id": "pathway_10093928", "reactome": "R-BTA-975576", "name": "N-glycan antennae elongation in the medial/trans-Golgi", "reactions": [ "reaction_10056061", "reaction_10076415", "reaction_10054418", "reaction_10077710", "reaction_10054431", "reaction_10056074", "reaction_10077717", "reaction_10054438", "reaction_10054467", "reaction_10054474", "reaction_10076422", "reaction_10054411" ] }, "R-BTA-611105": { "id": "pathway_10092968", "reactome": "R-BTA-611105", "name": "Respiratory electron transport", "reactions": [ "reaction_10080521", "reaction_10080519", "reaction_10080517", "reaction_10038895", "reaction_10080515", "reaction_10038647" ] }, "R-BTA-72737": { "id": "pathway_10092576", "reactome": "R-BTA-72737", "name": "Cap-dependent Translation Initiation", "reactions": [ "reaction_10034855", "reaction_10034365", "reaction_10034383", "reaction_10034387", "reaction_10034905" ] }, "R-BTA-190236": { "id": "pathway_10093176", "reactome": "R-BTA-190236", "name": "Signaling by FGFR", "reactions": [ "reaction_10072979", "reaction_10073147", "reaction_10057327", "reaction_10040769", "reaction_10072993", "reaction_10040744", "reaction_10040779", "reaction_10073077", "reaction_10073234", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10053082", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10072999", "reaction_10087373", "reaction_10073102", "reaction_10073001", "reaction_10073031", "reaction_10072957", "reaction_10073184", "reaction_10073119", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10072946", "reaction_10073326", "reaction_10072939", "reaction_10073108", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10073225", "reaction_10057314", "reaction_10073122", "reaction_10040696", "reaction_10073133", "reaction_10073011", "reaction_10073044", "reaction_10073228", "reaction_10072909", "reaction_10057704", "reaction_10087370", "reaction_10040773", "reaction_10073328", "reaction_10073071", "reaction_10057337", "reaction_10073041", "reaction_10040782", "reaction_10073222", "reaction_10072929", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10072976", "reaction_10073199", "reaction_10073004", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10073237", "reaction_10073246", "reaction_10040720", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10073215", "reaction_10073014", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10073019", "reaction_10072935", "reaction_10072920", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10073242", "reaction_10087367", "reaction_10073166", "reaction_10083935", "reaction_10057707", "reaction_10040704", "reaction_10073152", "reaction_10073140", "reaction_10072931", "reaction_10087376", "reaction_10073097", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10057302" ] }, "R-BTA-8853659": { "id": "pathway_10094762", "reactome": "R-BTA-8853659", "name": "RET signaling", "reactions": [ "reaction_10084326", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10084330", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10084311", "reaction_10084196", "reaction_10084194", "reaction_10084135", "reaction_10084309", "reaction_10084393", "reaction_10084185", "reaction_10084198", "reaction_10084169", "reaction_10084141", "reaction_10084379", "reaction_10084131", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-1855191": { "id": "pathway_10094172", "reactome": "R-BTA-1855191", "name": "Synthesis of IPs in the nucleus", "reactions": [ "reaction_10061128", "reaction_10061049", "reaction_10061137", "reaction_10060951", "reaction_10060993", "reaction_10061131", "reaction_10061017", "reaction_10061052", "reaction_10061119", "reaction_10061031" ] }, "R-BTA-3371497": { "id": "pathway_10094358", "reactome": "R-BTA-3371497", "name": "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "reactions": [ "reaction_10067955", "reaction_10068022" ] }, "R-BTA-2555396": { "id": "pathway_10094300", "reactome": "R-BTA-2555396", "name": "Mitotic Metaphase and Anaphase", "reactions": [ "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10065708", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-209952": { "id": "pathway_10093530", "reactome": "R-BTA-209952", "name": "Peptide hormone biosynthesis", "reactions": [ "reaction_10045696", "reaction_10045736", "reaction_10045744", "reaction_10045694" ] }, "R-BTA-9006925": { "id": "pathway_10092792", "reactome": "R-BTA-9006925", "name": "Intracellular signaling by second messengers", "reactions": [ "reaction_10060556", "reaction_10037022", "reaction_10037004", "reaction_10065227", "reaction_10060448", "reaction_10049478", "reaction_10041863", "reaction_10065099", "reaction_10037024", "reaction_10036981", "reaction_10087531" ] }, "R-BTA-379397": { "id": "pathway_10093542", "reactome": "R-BTA-379397", "name": "Enzymatic degradation of dopamine by COMT", "reactions": [ "reaction_10046153", "reaction_10088657" ] }, "R-BTA-174417": { "id": "pathway_10095018", "reactome": "R-BTA-174417", "name": "Telomere C-strand (Lagging Strand) Synthesis", "reactions": [ "reaction_10091663" ] }, "R-BTA-1296053": { "id": "pathway_10094036", "reactome": "R-BTA-1296053", "name": "Classical Kir channels", "reactions": [ "reaction_10057418" ] }, "R-BTA-196854": { "id": "pathway_10092520", "reactome": "R-BTA-196854", "name": "Metabolism of vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10085855", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10038427", "reaction_10066401", "reaction_10041772", "reaction_10081928", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10090493", "reaction_10041840", "reaction_10066249", "reaction_10041790", "reaction_10069948", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10058514", "reaction_10053350", "reaction_10086748", "reaction_10054395", "reaction_10041753", "reaction_10058524", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10070971", "reaction_10058511", "reaction_10081977", "reaction_10081935", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10054375", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10058785", "reaction_10065445", "reaction_10066247", "reaction_10065437", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10086750", "reaction_10053363", "reaction_10065441", "reaction_10081984", "reaction_10064591", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10085853", "reaction_10046968", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-975155": { "id": "pathway_10093026", "reactome": "R-BTA-975155", "name": "MyD88 dependent cascade initiated on endosome", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-113418": { "id": "pathway_10092812", "reactome": "R-BTA-113418", "name": "Formation of the Early Elongation Complex", "reactions": [ "reaction_10037205", "reaction_10037203" ] }, "R-BTA-8980692": { "id": "pathway_10094862", "reactome": "R-BTA-8980692", "name": "RHOA GTPase cycle", "reactions": [ "reaction_10089890", "reaction_10089860", "reaction_10089930", "reaction_10089888", "reaction_10089149", "reaction_10089011" ] }, "R-BTA-9623433": { "id": "pathway_10094952", "reactome": "R-BTA-9623433", "name": "NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis", "reactions": [ "reaction_10090571", "reaction_10090567", "reaction_10090555" ] }, "R-BTA-9029569": { "id": "pathway_10094922", "reactome": "R-BTA-9029569", "name": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux", "reactions": [ "reaction_10090456", "reaction_10090563", "reaction_10090559", "reaction_10090452" ] }, "R-BTA-8852405": { "id": "pathway_10094678", "reactome": "R-BTA-8852405", "name": "Signaling by MST1", "reactions": [ "reaction_10084080", "reaction_10084067", "reaction_10080870" ] }, "R-BTA-8876198": { "id": "pathway_10094800", "reactome": "R-BTA-8876198", "name": "RAB GEFs exchange GTP for GDP on RABs", "reactions": [ "reaction_10085988", "reaction_10086097", "reaction_10086136", "reaction_10085932", "reaction_10086209", "reaction_10086019", "reaction_10086182", "reaction_10086054" ] }, "R-BTA-425986": { "id": "pathway_10093706", "reactome": "R-BTA-425986", "name": "Sodium/Proton exchangers", "reactions": [ "reaction_10048567", "reaction_10048550" ] }, "R-BTA-1482922": { "id": "pathway_10094098", "reactome": "R-BTA-1482922", "name": "Acyl chain remodelling of PI", "reactions": [ "reaction_10058841", "reaction_10059000", "reaction_10059026", "reaction_10059851", "reaction_10058874", "reaction_10058975" ] }, "R-BTA-212165": { "id": "pathway_10093442", "reactome": "R-BTA-212165", "name": "Epigenetic regulation of gene expression", "reactions": [ "reaction_10070702", "reaction_10070700", "reaction_10044381", "reaction_10044390", "reaction_10071065", "reaction_10044333", "reaction_10048682", "reaction_10048717", "reaction_10048720", "reaction_10044361" ] }, "R-BTA-1566948": { "id": "pathway_10094222", "reactome": "R-BTA-1566948", "name": "Elastic fibre formation", "reactions": [ "reaction_10065336", "reaction_10064435", "reaction_10065435", "reaction_10063839", "reaction_10064437" ] }, "R-BTA-9013408": { "id": "pathway_10094894", "reactome": "R-BTA-9013408", "name": "RHOG GTPase cycle", "reactions": [ "reaction_10090125", "reaction_10090145", "reaction_10090098", "reaction_10090119", "reaction_10090115", "reaction_10090103" ] }, "R-BTA-9706019": { "id": "pathway_10095038", "reactome": "R-BTA-9706019", "name": "RHOBTB3 ATPase cycle", "reactions": [ "reaction_10092203", "reaction_10092208", "reaction_10092205" ] }, "R-BTA-3295583": { "id": "pathway_10094346", "reactome": "R-BTA-3295583", "name": "TRP channels", "reactions": [ "reaction_10092050", "reaction_10067332", "reaction_10067346" ] }, "R-BTA-166187": { "id": "pathway_10093010", "reactome": "R-BTA-166187", "name": "Mitochondrial Uncoupling", "reactions": [ "reaction_10039240", "reaction_10039254", "reaction_10039604", "reaction_10039242" ] }, "R-BTA-3247509": { "id": "pathway_10093976", "reactome": "R-BTA-3247509", "name": "Chromatin modifying enzymes", "reactions": [ "reaction_10072790", "reaction_10069838", "reaction_10070757", "reaction_10073406", "reaction_10073416", "reaction_10069939", "reaction_10070377", "reaction_10069937", "reaction_10070516", "reaction_10072725", "reaction_10073382", "reaction_10067596", "reaction_10072655", "reaction_10070392", "reaction_10070896", "reaction_10069796", "reaction_10056383", "reaction_10073384", "reaction_10070409", "reaction_10072755", "reaction_10068569", "reaction_10073396", "reaction_10072788", "reaction_10073380", "reaction_10069719", "reaction_10069754", "reaction_10071886", "reaction_10069769", "reaction_10069747", "reaction_10073394", "reaction_10068725", "reaction_10072752", "reaction_10073404", "reaction_10066651", "reaction_10069740", "reaction_10072750", "reaction_10072778", "reaction_10066966", "reaction_10070520", "reaction_10070962", "reaction_10073402", "reaction_10069846", "reaction_10070282", "reaction_10073400", "reaction_10068699", "reaction_10072823", "reaction_10085017", "reaction_10072813", "reaction_10091745", "reaction_10068844" ] }, "R-BTA-1280215": { "id": "pathway_10093068", "reactome": "R-BTA-1280215", "name": "Cytokine Signaling in Immune system", "reactions": [ "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10051936", "reaction_10052213", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10056268", "reaction_10051762", "reaction_10052254", "reaction_10089466", "reaction_10074266", "reaction_10054791", "reaction_10051696", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10092165", "reaction_10089691", "reaction_10050231", "reaction_10070719", "reaction_10042826", "reaction_10077790", "reaction_10051966", "reaction_10052196", "reaction_10073690", "reaction_10050011", "reaction_10089329", "reaction_10092257", "reaction_10090919", "reaction_10051786", "reaction_10090844", "reaction_10092043", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10074280", "reaction_10043488", "reaction_10074314", "reaction_10052337", "reaction_10077874", "reaction_10051774", "reaction_10092108", "reaction_10049970", "reaction_10052217", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10089341", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10092139", "reaction_10055958", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10092126", "reaction_10056110", "reaction_10071975", "reaction_10051737", "reaction_10074340", "reaction_10071982", "reaction_10089431", "reaction_10089540", "reaction_10073757", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10052067", "reaction_10090031", "reaction_10089536", "reaction_10056287", "reaction_10052210", "reaction_10089251", "reaction_10057834", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10054779", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10092173", "reaction_10091723", "reaction_10090027", "reaction_10074312", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10051818", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10055955", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10057823", "reaction_10074318", "reaction_10056289", "reaction_10050256", "reaction_10056194", "reaction_10055946", "reaction_10055967", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10090916", "reaction_10089689", "reaction_10092195", "reaction_10074320", "reaction_10052236", "reaction_10043867", "reaction_10077723", "reaction_10089349", "reaction_10060694", "reaction_10052147", "reaction_10051780", "reaction_10056132", "reaction_10084305", "reaction_10051748", "reaction_10073765", "reaction_10051771", "reaction_10092183", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10092151", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10091725", "reaction_10056207", "reaction_10092147", "reaction_10052229", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10076165", "reaction_10056315", "reaction_10089542", "reaction_10092033", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10089703", "reaction_10087766", "reaction_10060730", "reaction_10056335", "reaction_10049928", "reaction_10073708", "reaction_10050428", "reaction_10083522", "reaction_10071948", "reaction_10051792", "reaction_10060412", "reaction_10089696", "reaction_10039508", "reaction_10052159", "reaction_10050420", "reaction_10072030", "reaction_10087650", "reaction_10056283", "reaction_10052327", "reaction_10052233", "reaction_10089736", "reaction_10092143", "reaction_10051949", "reaction_10089269", "reaction_10076237", "reaction_10092159", "reaction_10052189", "reaction_10074308", "reaction_10089597", "reaction_10056297", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074306", "reaction_10074310", "reaction_10092141", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10054524", "reaction_10092137", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10092040", "reaction_10085017", "reaction_10051954", "reaction_10057836", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-1299503": { "id": "pathway_10094042", "reactome": "R-BTA-1299503", "name": "TWIK related potassium channel (TREK)", "reactions": [ "reaction_10057588" ] }, "R-BTA-877312": { "id": "pathway_10093862", "reactome": "R-BTA-877312", "name": "Regulation of IFNG signaling", "reactions": [ "reaction_10051818", "reaction_10055967", "reaction_10051792" ] }, "R-BTA-5668599": { "id": "pathway_10094558", "reactome": "R-BTA-5668599", "name": "RHO GTPases Activate NADPH Oxidases", "reactions": [ "reaction_10091169", "reaction_10073731", "reaction_10091180", "reaction_10073755", "reaction_10091175", "reaction_10073716" ] }, "R-BTA-450294": { "id": "pathway_10093060", "reactome": "R-BTA-450294", "name": "MAP kinase activation", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-171007": { "id": "pathway_10093104", "reactome": "R-BTA-171007", "name": "p38MAPK events", "reactions": [ "reaction_10039736", "reaction_10040570" ] }, "R-BTA-73728": { "id": "pathway_10092598", "reactome": "R-BTA-73728", "name": "RNA Polymerase I Promoter Opening", "reactions": [ "reaction_10035254" ] }, "R-BTA-5620971": { "id": "pathway_10092824", "reactome": "R-BTA-5620971", "name": "Pyroptosis", "reactions": [ "reaction_10092350", "reaction_10092354", "reaction_10091425", "reaction_10037253", "reaction_10091429", "reaction_10091439", "reaction_10092358", "reaction_10092356", "reaction_10091415", "reaction_10081905", "reaction_10092352", "reaction_10091423", "reaction_10092341", "reaction_10091409" ] }, "R-BTA-77289": { "id": "pathway_10092524", "reactome": "R-BTA-77289", "name": "Mitochondrial Fatty Acid Beta-Oxidation", "reactions": [ "reaction_10033889", "reaction_10076806", "reaction_10036220", "reaction_10036023", "reaction_10036021", "reaction_10036025", "reaction_10033912", "reaction_10033896", "reaction_10036038", "reaction_10075607", "reaction_10036029", "reaction_10036042", "reaction_10036040", "reaction_10036664", "reaction_10075631", "reaction_10086403", "reaction_10036027", "reaction_10036218", "reaction_10036012" ] }, "R-BTA-1168372": { "id": "pathway_10093966", "reactome": "R-BTA-1168372", "name": "Downstream signaling events of B Cell Receptor (BCR)", "reactions": [ "reaction_10091817", "reaction_10056239" ] }, "R-BTA-3214858": { "id": "pathway_10094428", "reactome": "R-BTA-3214858", "name": "RMTs methylate histone arginines", "reactions": [ "reaction_10070520", "reaction_10070392", "reaction_10070757", "reaction_10070896", "reaction_10073416", "reaction_10070282", "reaction_10070409", "reaction_10070377", "reaction_10070516" ] }, "R-BTA-389542": { "id": "pathway_10093584", "reactome": "R-BTA-389542", "name": "NADPH regeneration", "reactions": [ "reaction_10046968" ] }, "R-BTA-197264": { "id": "pathway_10093290", "reactome": "R-BTA-197264", "name": "Nicotinamide salvaging", "reactions": [ "reaction_10041808", "reaction_10082143", "reaction_10065210", "reaction_10081984", "reaction_10071643", "reaction_10081977", "reaction_10088867", "reaction_10049170", "reaction_10041824", "reaction_10086623" ] }, "R-BTA-3214847": { "id": "pathway_10094348", "reactome": "R-BTA-3214847", "name": "HATs acetylate histones", "reactions": [ "reaction_10071886", "reaction_10067596", "reaction_10068569" ] }, "R-BTA-416476": { "id": "pathway_10092846", "reactome": "R-BTA-416476", "name": "G alpha (q) signalling events", "reactions": [ "reaction_10047979", "reaction_10089224", "reaction_10037549", "reaction_10089222", "reaction_10064915", "reaction_10064910", "reaction_10041950", "reaction_10048580", "reaction_10076743", "reaction_10064919", "reaction_10048543", "reaction_10048632", "reaction_10048587", "reaction_10089203", "reaction_10048660", "reaction_10047823", "reaction_10046149" ] }, "R-BTA-352238": { "id": "pathway_10093462", "reactome": "R-BTA-352238", "name": "Breakdown of the nuclear lamina", "reactions": [ "reaction_10044578", "reaction_10044568", "reaction_10090575" ] }, "R-BTA-73856": { "id": "pathway_10092722", "reactome": "R-BTA-73856", "name": "RNA Polymerase II Transcription Termination", "reactions": [ "reaction_10036915", "reaction_10036080" ] }, "R-BTA-1280218": { "id": "pathway_10093314", "reactome": "R-BTA-1280218", "name": "Adaptive Immune System", "reactions": [ "reaction_10075009", "reaction_10065009", "reaction_10043302", "reaction_10055821", "reaction_10053213", "reaction_10065051", "reaction_10046932", "reaction_10046807", "reaction_10043300", "reaction_10055448", "reaction_10046888", "reaction_10083967", "reaction_10046909", "reaction_10042129", "reaction_10043262", "reaction_10043212", "reaction_10042253", "reaction_10056805", "reaction_10064219", "reaction_10043659", "reaction_10055783", "reaction_10055491", "reaction_10065055", "reaction_10087823", "reaction_10043274", "reaction_10057004", "reaction_10063972", "reaction_10047530", "reaction_10084658", "reaction_10056910", "reaction_10043219", "reaction_10065227", "reaction_10042623", "reaction_10075923", "reaction_10083959", "reaction_10046787", "reaction_10043182", "reaction_10055453", "reaction_10055444", "reaction_10074901", "reaction_10046903", "reaction_10065011", "reaction_10043298", "reaction_10043304", "reaction_10064068", "reaction_10084867", "reaction_10043270", "reaction_10056912", "reaction_10046959", "reaction_10064214", "reaction_10091743", "reaction_10055451", "reaction_10043244", "reaction_10064221", "reaction_10056982", "reaction_10056914", "reaction_10074993", "reaction_10056903", "reaction_10074899", "reaction_10055431", "reaction_10065019", "reaction_10076963", "reaction_10065021", "reaction_10055817", "reaction_10043193", "reaction_10043252", "reaction_10087807", "reaction_10055460", "reaction_10046907", "reaction_10046943", "reaction_10056835", "reaction_10047519", "reaction_10054866", "reaction_10091817", "reaction_10046811", "reaction_10052471", "reaction_10084672", "reaction_10046822", "reaction_10043225", "reaction_10042786", "reaction_10052466", "reaction_10084401", "reaction_10045016", "reaction_10043241", "reaction_10042635", "reaction_10046834", "reaction_10064118", "reaction_10047536", "reaction_10046951", "reaction_10064277", "reaction_10084865", "reaction_10055819", "reaction_10056239" ] }, "R-BTA-190241": { "id": "pathway_10093182", "reactome": "R-BTA-190241", "name": "FGFR2 ligand binding and activation", "reactions": [ "reaction_10040785", "reaction_10040720", "reaction_10073328", "reaction_10040788", "reaction_10040744" ] }, "R-BTA-1461957": { "id": "pathway_10094082", "reactome": "R-BTA-1461957", "name": "Beta defensins", "reactions": [ "reaction_10058492", "reaction_10058486", "reaction_10058456", "reaction_10061657" ] }, "R-BTA-2024096": { "id": "pathway_10094160", "reactome": "R-BTA-2024096", "name": "HS-GAG degradation", "reactions": [ "reaction_10063801", "reaction_10060625", "reaction_10063803", "reaction_10060671", "reaction_10063805", "reaction_10063022", "reaction_10060685", "reaction_10060678", "reaction_10060741", "reaction_10060634" ] }, "R-BTA-71387": { "id": "pathway_10092456", "reactome": "R-BTA-71387", "name": "Metabolism of carbohydrates", "reactions": [ "reaction_10039887", "reaction_10077793", "reaction_10033592", "reaction_10062697", "reaction_10036903", "reaction_10073438", "reaction_10034118", "reaction_10090645", "reaction_10063216", "reaction_10088737", "reaction_10064393", "reaction_10063807", "reaction_10051589", "reaction_10060634", "reaction_10063485", "reaction_10062701", "reaction_10091289", "reaction_10034013", "reaction_10063508", "reaction_10061251", "reaction_10064353", "reaction_10064597", "reaction_10033561", "reaction_10060829", "reaction_10034157", "reaction_10033638", "reaction_10063022", "reaction_10041878", "reaction_10061395", "reaction_10033620", "reaction_10063249", "reaction_10063510", "reaction_10063610", "reaction_10061651", "reaction_10080765", "reaction_10060741", "reaction_10060827", "reaction_10061612", "reaction_10090854", "reaction_10060295", "reaction_10045692", "reaction_10063010", "reaction_10078710", "reaction_10064355", "reaction_10090851", "reaction_10042801", "reaction_10090772", "reaction_10080747", "reaction_10060031", "reaction_10034071", "reaction_10067610", "reaction_10076815", "reaction_10067254", "reaction_10045043", "reaction_10089230", "reaction_10080756", "reaction_10050637", "reaction_10063633", "reaction_10090620", "reaction_10067240", "reaction_10034041", "reaction_10045029", "reaction_10063603", "reaction_10090696", "reaction_10045050", "reaction_10090638", "reaction_10034944", "reaction_10063532", "reaction_10090856", "reaction_10091286", "reaction_10033718", "reaction_10041885", "reaction_10068748", "reaction_10064595", "reaction_10063520", "reaction_10067247", "reaction_10061642", "reaction_10090703", "reaction_10088744", "reaction_10060685", "reaction_10067639", "reaction_10063801", "reaction_10091291", "reaction_10033611", "reaction_10090799", "reaction_10033629", "reaction_10063803", "reaction_10067634", "reaction_10039890", "reaction_10091293", "reaction_10048727", "reaction_10060678", "reaction_10072894", "reaction_10060825", "reaction_10060625", "reaction_10033570", "reaction_10090611", "reaction_10063232", "reaction_10063805", "reaction_10061402", "reaction_10063014", "reaction_10062508", "reaction_10034043", "reaction_10062463", "reaction_10034238", "reaction_10062674", "reaction_10090867", "reaction_10034032", "reaction_10062984", "reaction_10033579", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10072825", "reaction_10061350", "reaction_10060293", "reaction_10090802", "reaction_10060671", "reaction_10062655", "reaction_10064593", "reaction_10090822", "reaction_10033594", "reaction_10063477", "reaction_10090819", "reaction_10060842", "reaction_10088898", "reaction_10084129", "reaction_10073431", "reaction_10067648", "reaction_10060285", "reaction_10067622", "reaction_10068755", "reaction_10063530", "reaction_10090631", "reaction_10090774", "reaction_10051570", "reaction_10067644", "reaction_10063586", "reaction_10034138", "reaction_10090797", "reaction_10034140", "reaction_10083115", "reaction_10064391" ] }, "R-BTA-8984722": { "id": "pathway_10094840", "reactome": "R-BTA-8984722", "name": "Interleukin-35 Signalling", "reactions": [ "reaction_10089321", "reaction_10087763", "reaction_10089329", "reaction_10089331", "reaction_10089333", "reaction_10087780" ] }, "R-BTA-8963693": { "id": "pathway_10092490", "reactome": "R-BTA-8963693", "name": "Aspartate and asparagine metabolism", "reactions": [ "reaction_10033716", "reaction_10076130", "reaction_10045029", "reaction_10033728", "reaction_10076406", "reaction_10033718", "reaction_10033737", "reaction_10078529" ] }, "R-BTA-112412": { "id": "pathway_10092638", "reactome": "R-BTA-112412", "name": "SOS-mediated signalling", "reactions": [ "reaction_10035507" ] }, "R-BTA-209931": { "id": "pathway_10093408", "reactome": "R-BTA-209931", "name": "Serotonin and melatonin biosynthesis", "reactions": [ "reaction_10043948", "reaction_10043917" ] }, "R-BTA-2022377": { "id": "pathway_10094988", "reactome": "R-BTA-2022377", "name": "Metabolism of Angiotensinogen to Angiotensins", "reactions": [ "reaction_10091056" ] }, "R-BTA-8964540": { "id": "pathway_10092484", "reactome": "R-BTA-8964540", "name": "Alanine metabolism", "reactions": [ "reaction_10033681" ] }, "R-BTA-156827": { "id": "pathway_10092906", "reactome": "R-BTA-156827", "name": "L13a-mediated translational silencing of Ceruloplasmin expression", "reactions": [ "reaction_10038082" ] }, "R-BTA-5675482": { "id": "pathway_10094366", "reactome": "R-BTA-5675482", "name": "Regulation of necroptotic cell death", "reactions": [ "reaction_10091779", "reaction_10091773", "reaction_10074254", "reaction_10091793", "reaction_10071534", "reaction_10091808", "reaction_10074240", "reaction_10091806", "reaction_10068030", "reaction_10091810", "reaction_10091783" ] }, "R-BTA-112315": { "id": "pathway_10092498", "reactome": "R-BTA-112315", "name": "Transmission across Chemical Synapses", "reactions": [ "reaction_10046552", "reaction_10051085", "reaction_10039653", "reaction_10033746", "reaction_10081481", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10049090", "reaction_10051989", "reaction_10049583", "reaction_10033755", "reaction_10052013", "reaction_10052018", "reaction_10050517", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10071437", "reaction_10046151", "reaction_10054318", "reaction_10051999", "reaction_10038000", "reaction_10045419", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10054372", "reaction_10045423", "reaction_10088657", "reaction_10036981", "reaction_10051498", "reaction_10044076", "reaction_10044540", "reaction_10090547", "reaction_10044086", "reaction_10051525", "reaction_10049478", "reaction_10051523", "reaction_10046153", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10039664" ] }, "R-BTA-168249": { "id": "pathway_10093004", "reactome": "R-BTA-168249", "name": "Innate Immune System", "reactions": [ "reaction_10063376", "reaction_10050196", "reaction_10066551", "reaction_10078759", "reaction_10066144", "reaction_10066102", "reaction_10056531", "reaction_10053134", "reaction_10072364", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10066536", "reaction_10080844", "reaction_10063374", "reaction_10067223", "reaction_10077921", "reaction_10066094", "reaction_10072388", "reaction_10066141", "reaction_10050231", "reaction_10056088", "reaction_10042826", "reaction_10065402", "reaction_10081265", "reaction_10072045", "reaction_10065413", "reaction_10063353", "reaction_10090400", "reaction_10081510", "reaction_10039217", "reaction_10061502", "reaction_10051836", "reaction_10083100", "reaction_10080435", "reaction_10065407", "reaction_10081397", "reaction_10067233", "reaction_10080842", "reaction_10053048", "reaction_10072057", "reaction_10056416", "reaction_10043488", "reaction_10086405", "reaction_10072011", "reaction_10082012", "reaction_10056084", "reaction_10083106", "reaction_10040197", "reaction_10081385", "reaction_10085369", "reaction_10082967", "reaction_10039465", "reaction_10060783", "reaction_10053058", "reaction_10079949", "reaction_10079199", "reaction_10054678", "reaction_10071975", "reaction_10071982", "reaction_10061657", "reaction_10050218", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10043182", "reaction_10080063", "reaction_10050254", "reaction_10065517", "reaction_10066082", "reaction_10077924", "reaction_10041950", "reaction_10070906", "reaction_10072383", "reaction_10066127", "reaction_10060785", "reaction_10039778", "reaction_10072374", "reaction_10072002", "reaction_10066180", "reaction_10065894", "reaction_10084706", "reaction_10066151", "reaction_10050192", "reaction_10066059", "reaction_10058492", "reaction_10066238", "reaction_10081559", "reaction_10081404", "reaction_10067229", "reaction_10072061", "reaction_10081406", "reaction_10081410", "reaction_10066080", "reaction_10084683", "reaction_10058486", "reaction_10078929", "reaction_10066052", "reaction_10081943", "reaction_10079653", "reaction_10066147", "reaction_10050256", "reaction_10067225", "reaction_10066120", "reaction_10080831", "reaction_10084636", "reaction_10061174", "reaction_10054649", "reaction_10055971", "reaction_10066172", "reaction_10065642", "reaction_10079391", "reaction_10060773", "reaction_10080719", "reaction_10081905", "reaction_10056539", "reaction_10082977", "reaction_10053122", "reaction_10081432", "reaction_10072053", "reaction_10082004", "reaction_10084020", "reaction_10090019", "reaction_10092318", "reaction_10077926", "reaction_10065491", "reaction_10072006", "reaction_10058388", "reaction_10041863", "reaction_10082008", "reaction_10066559", "reaction_10066880", "reaction_10039782", "reaction_10039481", "reaction_10050208", "reaction_10054736", "reaction_10053095", "reaction_10071948", "reaction_10047907", "reaction_10082183", "reaction_10056082", "reaction_10067231", "reaction_10060759", "reaction_10039508", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10077919", "reaction_10063368", "reaction_10065388", "reaction_10056090", "reaction_10084322", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10058456", "reaction_10066168", "reaction_10066608", "reaction_10066532", "reaction_10053046", "reaction_10087797", "reaction_10081506", "reaction_10072392", "reaction_10081085", "reaction_10077904", "reaction_10072395" ] }, "R-BTA-446107": { "id": "pathway_10093748", "reactome": "R-BTA-446107", "name": "Type I hemidesmosome assembly", "reactions": [ "reaction_10049304" ] }, "R-BTA-5610780": { "id": "pathway_10094480", "reactome": "R-BTA-5610780", "name": "Degradation of GLI1 by the proteasome", "reactions": [ "reaction_10072138" ] }, "R-BTA-5693568": { "id": "pathway_10094598", "reactome": "R-BTA-5693568", "name": "Resolution of D-loop Structures through Holliday Junction Intermediates", "reactions": [ "reaction_10075165", "reaction_10075151" ] }, "R-BTA-190872": { "id": "pathway_10093204", "reactome": "R-BTA-190872", "name": "Transport of connexons to the plasma membrane", "reactions": [ "reaction_10040857", "reaction_10040842", "reaction_10050458" ] }, "R-BTA-110329": { "id": "pathway_10092748", "reactome": "R-BTA-110329", "name": "Cleavage of the damaged pyrimidine ", "reactions": [ "reaction_10036716", "reaction_10036767", "reaction_10036709", "reaction_10036729", "reaction_10036736", "reaction_10036743" ] }, "R-BTA-8878166": { "id": "pathway_10094826", "reactome": "R-BTA-8878166", "name": "Transcriptional regulation by RUNX2", "reactions": [ "reaction_10089679", "reaction_10089681", "reaction_10089357", "reaction_10086716", "reaction_10089640", "reaction_10089610", "reaction_10086724" ] }, "R-BTA-70263": { "id": "pathway_10092476", "reactome": "R-BTA-70263", "name": "Gluconeogenesis", "reactions": [ "reaction_10045692", "reaction_10067240", "reaction_10067247", "reaction_10033757", "reaction_10067254", "reaction_10033638", "reaction_10045029", "reaction_10045043", "reaction_10045050", "reaction_10034238", "reaction_10033718", "reaction_10041878", "reaction_10041885" ] }, "R-BTA-5693579": { "id": "pathway_10094590", "reactome": "R-BTA-5693579", "name": "Homologous DNA Pairing and Strand Exchange", "reactions": [ "reaction_10074877" ] }, "R-BTA-68875": { "id": "pathway_10094258", "reactome": "R-BTA-68875", "name": "Mitotic Prophase", "reactions": [ "reaction_10070705", "reaction_10065572", "reaction_10065095", "reaction_10064733", "reaction_10066345", "reaction_10065563", "reaction_10065177", "reaction_10064904", "reaction_10065201", "reaction_10069491", "reaction_10066324" ] }, "R-BTA-177135": { "id": "pathway_10092932", "reactome": "R-BTA-177135", "name": "Conjugation of benzoate with glycine", "reactions": [ "reaction_10038371", "reaction_10038354" ] }, "R-BTA-111452": { "id": "pathway_10092816", "reactome": "R-BTA-111452", "name": "Activation and oligomerization of BAK protein", "reactions": [ "reaction_10037622", "reaction_10037237", "reaction_10039520" ] }, "R-BTA-373080": { "id": "pathway_10092984", "reactome": "R-BTA-373080", "name": "Class B/2 (Secretin family receptors)", "reactions": [ "reaction_10048304", "reaction_10048248", "reaction_10048326", "reaction_10051907", "reaction_10048270", "reaction_10048282", "reaction_10086575", "reaction_10038918", "reaction_10049681", "reaction_10086565" ] }, "R-BTA-1963640": { "id": "pathway_10094062", "reactome": "R-BTA-1963640", "name": "GRB2 events in ERBB2 signaling", "reactions": [ "reaction_10057695", "reaction_10057692" ] }, "R-BTA-434316": { "id": "pathway_10093654", "reactome": "R-BTA-434316", "name": "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion", "reactions": [ "reaction_10047809" ] }, "R-BTA-448424": { "id": "pathway_10093064", "reactome": "R-BTA-448424", "name": "Interleukin-17 signaling", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-6806667": { "id": "pathway_10092950", "reactome": "R-BTA-6806667", "name": "Metabolism of fat-soluble vitamins", "reactions": [ "reaction_10085855", "reaction_10038427", "reaction_10054382", "reaction_10065445", "reaction_10069948", "reaction_10054404", "reaction_10066247", "reaction_10090493", "reaction_10065437", "reaction_10070971", "reaction_10081928", "reaction_10054393", "reaction_10081935", "reaction_10085853", "reaction_10065441", "reaction_10054375", "reaction_10066249", "reaction_10054395" ] }, "R-BTA-5357905": { "id": "pathway_10094356", "reactome": "R-BTA-5357905", "name": "Regulation of TNFR1 signaling", "reactions": [ "reaction_10092031", "reaction_10071541", "reaction_10071534", "reaction_10067895", "reaction_10084723", "reaction_10092026" ] }, "R-BTA-420499": { "id": "pathway_10093504", "reactome": "R-BTA-420499", "name": "Class C/3 (Metabotropic glutamate/pheromone receptors)", "reactions": [ "reaction_10049643", "reaction_10067348", "reaction_10045138" ] }, "R-BTA-9013973": { "id": "pathway_10093076", "reactome": "R-BTA-9013973", "name": "TICAM1-dependent activation of IRF3/IRF7", "reactions": [ "reaction_10040197", "reaction_10039560" ] }, "R-BTA-1483166": { "id": "pathway_10092666", "reactome": "R-BTA-1483166", "name": "Synthesis of PA", "reactions": [ "reaction_10059114", "reaction_10035812", "reaction_10058908", "reaction_10077777", "reaction_10058923", "reaction_10051264", "reaction_10086248", "reaction_10059860", "reaction_10058858", "reaction_10058834", "reaction_10035786", "reaction_10088649", "reaction_10058896" ] }, "R-BTA-8955332": { "id": "pathway_10094794", "reactome": "R-BTA-8955332", "name": "Carboxyterminal post-translational modifications of tubulin", "reactions": [ "reaction_10085250", "reaction_10085101" ] }, "R-BTA-9006936": { "id": "pathway_10093336", "reactome": "R-BTA-9006936", "name": "Signaling by TGFB family members", "reactions": [ "reaction_10064933", "reaction_10084542", "reaction_10056356", "reaction_10043311", "reaction_10056354", "reaction_10042976", "reaction_10071262" ] }, "R-BTA-4641257": { "id": "pathway_10094370", "reactome": "R-BTA-4641257", "name": "Degradation of AXIN", "reactions": [ "reaction_10068086", "reaction_10068088", "reaction_10068078", "reaction_10068073" ] }, "R-BTA-8849474": { "id": "pathway_10094728", "reactome": "R-BTA-8849474", "name": "PTK6 Activates STAT3", "reactions": [ "reaction_10083487" ] }, "R-BTA-211958": { "id": "pathway_10093436", "reactome": "R-BTA-211958", "name": "Miscellaneous substrates", "reactions": [ "reaction_10044235", "reaction_10044255", "reaction_10044247", "reaction_10044158", "reaction_10044242" ] }, "R-BTA-69580": { "id": "pathway_10092446", "reactome": "R-BTA-69580", "name": "p53-Dependent G1/S DNA damage checkpoint", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-418038": { "id": "pathway_10093660", "reactome": "R-BTA-418038", "name": "Nucleotide-like (purinergic) receptors", "reactions": [ "reaction_10047866", "reaction_10047870", "reaction_10047868", "reaction_10048003", "reaction_10047862", "reaction_10047864", "reaction_10047851", "reaction_10047853", "reaction_10047989", "reaction_10047987", "reaction_10047857", "reaction_10090956", "reaction_10047860" ] }, "R-BTA-8934903": { "id": "pathway_10094832", "reactome": "R-BTA-8934903", "name": "Receptor Mediated Mitophagy", "reactions": [ "reaction_10088891", "reaction_10087615", "reaction_10087621" ] }, "R-BTA-1538133": { "id": "pathway_10094074", "reactome": "R-BTA-1538133", "name": "G0 and Early G1", "reactions": [ "reaction_10057808", "reaction_10057804", "reaction_10057812", "reaction_10057800" ] }, "R-BTA-456926": { "id": "pathway_10092838", "reactome": "R-BTA-456926", "name": "Thrombin signalling through proteinase activated receptors (PARs)", "reactions": [ "reaction_10092299", "reaction_10047886", "reaction_10047880", "reaction_10037433", "reaction_10037353", "reaction_10037580" ] }, "R-BTA-193775": { "id": "pathway_10093242", "reactome": "R-BTA-193775", "name": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol", "reactions": [ "reaction_10041337", "reaction_10041343", "reaction_10041363", "reaction_10041357", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041349", "reaction_10041351", "reaction_10041335", "reaction_10041193", "reaction_10041353", "reaction_10041361", "reaction_10041345", "reaction_10041367", "reaction_10041339", "reaction_10041217" ] }, "R-BTA-8849472": { "id": "pathway_10094742", "reactome": "R-BTA-8849472", "name": "PTK6 Down-Regulation", "reactions": [ "reaction_10083707", "reaction_10083729", "reaction_10083726" ] }, "R-BTA-5676590": { "id": "pathway_10094464", "reactome": "R-BTA-5676590", "name": "NIK-->noncanonical NF-kB signaling", "reactions": [ "reaction_10073708", "reaction_10071948", "reaction_10072030", "reaction_10071975", "reaction_10071982" ] }, "R-BTA-2980767": { "id": "pathway_10094318", "reactome": "R-BTA-2980767", "name": "Activation of NIMA Kinases NEK9, NEK6, NEK7", "reactions": [ "reaction_10066345", "reaction_10066324" ] }, "R-BTA-1266738": { "id": "pathway_10093388", "reactome": "R-BTA-1266738", "name": "Developmental Biology", "reactions": [ "reaction_10081917", "reaction_10081921", "reaction_10084311", "reaction_10089713", "reaction_10048951", "reaction_10045244", "reaction_10069146", "reaction_10083835", "reaction_10091007", "reaction_10047763", "reaction_10083824", "reaction_10084141", "reaction_10074613", "reaction_10085757", "reaction_10084153", "reaction_10074641", "reaction_10047735", "reaction_10069221", "reaction_10069157", "reaction_10069223", "reaction_10044090", "reaction_10045509", "reaction_10047618", "reaction_10069188", "reaction_10084135", "reaction_10084309", "reaction_10069418", "reaction_10045517", "reaction_10084393", "reaction_10043671", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10047455", "reaction_10047659", "reaction_10047717", "reaction_10084326", "reaction_10069285", "reaction_10084330", "reaction_10045224", "reaction_10083741", "reaction_10084187", "reaction_10045236", "reaction_10050085", "reaction_10047449", "reaction_10069192", "reaction_10069121", "reaction_10089397", "reaction_10091009", "reaction_10084185", "reaction_10069159", "reaction_10084379", "reaction_10084131", "reaction_10083743", "reaction_10085755", "reaction_10084149", "reaction_10082871", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10069435", "reaction_10069144", "reaction_10077943", "reaction_10047458", "reaction_10069131", "reaction_10084196", "reaction_10069226", "reaction_10050116", "reaction_10081857", "reaction_10049024", "reaction_10074603", "reaction_10090179", "reaction_10081915", "reaction_10081861", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10047753", "reaction_10084194", "reaction_10084313" ] }, "R-BTA-480985": { "id": "pathway_10094698", "reactome": "R-BTA-480985", "name": "Synthesis of dolichyl-phosphate-glucose", "reactions": [ "reaction_10082941" ] }, "R-BTA-5358508": { "id": "pathway_10094452", "reactome": "R-BTA-5358508", "name": "Mismatch Repair", "reactions": [ "reaction_10071628", "reaction_10071769", "reaction_10071630", "reaction_10071765", "reaction_10071767", "reaction_10071622", "reaction_10071638", "reaction_10071640", "reaction_10071617", "reaction_10071607" ] }, "R-BTA-397014": { "id": "pathway_10093604", "reactome": "R-BTA-397014", "name": "Muscle contraction", "reactions": [ "reaction_10048504", "reaction_10047186", "reaction_10057418", "reaction_10071819", "reaction_10047200", "reaction_10077468", "reaction_10071843", "reaction_10047893", "reaction_10071824", "reaction_10053180", "reaction_10048787", "reaction_10071800", "reaction_10091759", "reaction_10071876", "reaction_10047198", "reaction_10047196" ] }, "R-BTA-201681": { "id": "pathway_10093346", "reactome": "R-BTA-201681", "name": "TCF dependent signaling in response to WNT", "reactions": [ "reaction_10068078", "reaction_10068073", "reaction_10068704", "reaction_10069645", "reaction_10067879", "reaction_10067694", "reaction_10069664", "reaction_10067698", "reaction_10068088", "reaction_10071320", "reaction_10068707", "reaction_10069607", "reaction_10069647", "reaction_10068086", "reaction_10071330", "reaction_10068095", "reaction_10067696", "reaction_10059152", "reaction_10043129" ] }, "R-BTA-2453902": { "id": "pathway_10092632", "reactome": "R-BTA-2453902", "name": "The canonical retinoid cycle in rods (twilight vision)", "reactions": [ "reaction_10065597", "reaction_10088914", "reaction_10035558", "reaction_10035579", "reaction_10065644", "reaction_10035406", "reaction_10065606", "reaction_10065646", "reaction_10077751", "reaction_10065604" ] }, "R-BTA-442380": { "id": "pathway_10093766", "reactome": "R-BTA-442380", "name": "Zinc influx into cells by the SLC39 gene family", "reactions": [ "reaction_10049440", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-5223345": { "id": "pathway_10094434", "reactome": "R-BTA-5223345", "name": "Miscellaneous transport and binding events", "reactions": [ "reaction_10070735", "reaction_10071469", "reaction_10071476", "reaction_10071462", "reaction_10071280", "reaction_10087365", "reaction_10071490", "reaction_10086343" ] }, "R-BTA-392154": { "id": "pathway_10093674", "reactome": "R-BTA-392154", "name": "Nitric oxide stimulates guanylate cyclase", "reactions": [ "reaction_10047907", "reaction_10047930" ] }, "R-BTA-5221030": { "id": "pathway_10094432", "reactome": "R-BTA-5221030", "name": "TET1,2,3 and TDG demethylate DNA", "reactions": [ "reaction_10070700", "reaction_10070702" ] }, "R-BTA-170984": { "id": "pathway_10093078", "reactome": "R-BTA-170984", "name": "ARMS-mediated activation", "reactions": [ "reaction_10039592", "reaction_10039601", "reaction_10039581" ] }, "R-BTA-198203": { "id": "pathway_10093296", "reactome": "R-BTA-198203", "name": "PI3K/AKT activation", "reactions": [ "reaction_10041851", "reaction_10043315", "reaction_10041869" ] }, "R-BTA-1660662": { "id": "pathway_10094120", "reactome": "R-BTA-1660662", "name": "Glycosphingolipid metabolism", "reactions": [ "reaction_10060021", "reaction_10059977", "reaction_10059944", "reaction_10060109", "reaction_10059984", "reaction_10084410", "reaction_10059951", "reaction_10059961", "reaction_10060041", "reaction_10060012", "reaction_10071483", "reaction_10059991", "reaction_10060302", "reaction_10060316", "reaction_10059954", "reaction_10059968", "reaction_10071497", "reaction_10060309" ] }, "R-BTA-2393930": { "id": "pathway_10094284", "reactome": "R-BTA-2393930", "name": "Phosphate bond hydrolysis by NUDT proteins", "reactions": [ "reaction_10065378", "reaction_10065362", "reaction_10065371", "reaction_10065359", "reaction_10065381", "reaction_10065763", "reaction_10065760", "reaction_10065383", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10065386" ] }, "R-BTA-389513": { "id": "pathway_10093572", "reactome": "R-BTA-389513", "name": "CTLA4 inhibitory signaling", "reactions": [ "reaction_10046903", "reaction_10046909", "reaction_10046807", "reaction_10046959" ] }, "R-BTA-5624138": { "id": "pathway_10094496", "reactome": "R-BTA-5624138", "name": "Trafficking of myristoylated proteins to the cilium", "reactions": [ "reaction_10072497", "reaction_10072489" ] }, "R-BTA-68867": { "id": "pathway_10092398", "reactome": "R-BTA-68867", "name": "Assembly of the pre-replicative complex", "reactions": [ "reaction_10033379", "reaction_10033412" ] }, "R-BTA-170660": { "id": "pathway_10093100", "reactome": "R-BTA-170660", "name": "Adenylate cyclase activating pathway", "reactions": [ "reaction_10039674", "reaction_10039667", "reaction_10039658", "reaction_10039671" ] }, "R-BTA-390648": { "id": "pathway_10093610", "reactome": "R-BTA-390648", "name": "Muscarinic acetylcholine receptors", "reactions": [ "reaction_10047214", "reaction_10047210" ] }, "R-BTA-1483191": { "id": "pathway_10093452", "reactome": "R-BTA-1483191", "name": "Synthesis of PC", "reactions": [ "reaction_10085808", "reaction_10044540", "reaction_10085798", "reaction_10059094", "reaction_10059141", "reaction_10086064", "reaction_10059063", "reaction_10085024", "reaction_10085788" ] }, "R-BTA-9026395": { "id": "pathway_10094938", "reactome": "R-BTA-9026395", "name": "Biosynthesis of DHA-derived sulfido conjugates", "reactions": [ "reaction_10090480", "reaction_10090491", "reaction_10090489" ] }, "R-BTA-351200": { "id": "pathway_10093476", "reactome": "R-BTA-351200", "name": "Interconversion of polyamines", "reactions": [ "reaction_10044837", "reaction_10044835" ] }, "R-BTA-399956": { "id": "pathway_10093648", "reactome": "R-BTA-399956", "name": "CRMPs in Sema3A signaling", "reactions": [ "reaction_10047735", "reaction_10047753", "reaction_10047717" ] }, "R-BTA-391903": { "id": "pathway_10093626", "reactome": "R-BTA-391903", "name": "Eicosanoid ligand-binding receptors", "reactions": [ "reaction_10047396", "reaction_10047378", "reaction_10047374", "reaction_10047394", "reaction_10047398", "reaction_10047366", "reaction_10047380", "reaction_10091763", "reaction_10047364", "reaction_10047376", "reaction_10091812" ] }, "R-BTA-209776": { "id": "pathway_10093410", "reactome": "R-BTA-209776", "name": "Metabolism of amine-derived hormones", "reactions": [ "reaction_10043956", "reaction_10043978", "reaction_10043980", "reaction_10044828", "reaction_10076360", "reaction_10043917", "reaction_10043933", "reaction_10043986", "reaction_10043924", "reaction_10043948" ] }, "R-BTA-6804756": { "id": "pathway_10092430", "reactome": "R-BTA-6804756", "name": "Regulation of TP53 Activity through Phosphorylation", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10081563", "reaction_10066870", "reaction_10081602", "reaction_10066670", "reaction_10081595", "reaction_10078731", "reaction_10066712", "reaction_10033535", "reaction_10076341", "reaction_10080730", "reaction_10081629", "reaction_10081622", "reaction_10066704", "reaction_10078720" ] }, "R-BTA-68882": { "id": "pathway_10094298", "reactome": "R-BTA-68882", "name": "Mitotic Anaphase", "reactions": [ "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10065708", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-193697": { "id": "pathway_10093268", "reactome": "R-BTA-193697", "name": "p75NTR regulates axonogenesis", "reactions": [ "reaction_10041470" ] }, "R-BTA-5673001": { "id": "pathway_10094568", "reactome": "R-BTA-5673001", "name": "RAF/MAP kinase cascade", "reactions": [ "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10091490", "reaction_10073904", "reaction_10091506", "reaction_10073932", "reaction_10074238", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10074088", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10073940", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-453276": { "id": "pathway_10092898", "reactome": "R-BTA-453276", "name": "Regulation of mitotic cell cycle", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-70921": { "id": "pathway_10092510", "reactome": "R-BTA-70921", "name": "Histidine catabolism", "reactions": [ "reaction_10054585", "reaction_10033849", "reaction_10033833", "reaction_10033840", "reaction_10077758", "reaction_10086033" ] }, "R-BTA-9035034": { "id": "pathway_10095024", "reactome": "R-BTA-9035034", "name": "RHOF GTPase cycle", "reactions": [ "reaction_10091921", "reaction_10091832", "reaction_10091864" ] }, "R-BTA-446219": { "id": "pathway_10093222", "reactome": "R-BTA-446219", "name": "Synthesis of substrates in N-glycan biosythesis", "reactions": [ "reaction_10069371", "reaction_10077823", "reaction_10082941", "reaction_10069320", "reaction_10069359", "reaction_10069357", "reaction_10081490", "reaction_10049818", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10069368", "reaction_10040933", "reaction_10069373", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10077826", "reaction_10049831", "reaction_10049778", "reaction_10081497", "reaction_10069348", "reaction_10050153", "reaction_10048958", "reaction_10077816", "reaction_10069382" ] }, "R-BTA-1483076": { "id": "pathway_10094112", "reactome": "R-BTA-1483076", "name": "Synthesis of CL", "reactions": [ "reaction_10059066" ] }, "R-BTA-71032": { "id": "pathway_10092522", "reactome": "R-BTA-71032", "name": "Propionyl-CoA catabolism", "reactions": [ "reaction_10033912", "reaction_10033896", "reaction_10033889" ] }, "R-BTA-212300": { "id": "pathway_10093440", "reactome": "R-BTA-212300", "name": "PRC2 methylates histones and DNA", "reactions": [ "reaction_10044333", "reaction_10044361", "reaction_10044381", "reaction_10044390" ] }, "R-BTA-532668": { "id": "pathway_10093956", "reactome": "R-BTA-532668", "name": "N-glycan trimming in the ER and Calnexin/Calreticulin cycle", "reactions": [ "reaction_10056058" ] }, "R-BTA-422085": { "id": "pathway_10093698", "reactome": "R-BTA-422085", "name": "Synthesis, secretion, and deacylation of Ghrelin", "reactions": [ "reaction_10048429", "reaction_10048461", "reaction_10048465", "reaction_10048407" ] }, "R-BTA-3214815": { "id": "pathway_10094376", "reactome": "R-BTA-3214815", "name": "HDACs deacetylate histones", "reactions": [ "reaction_10068725", "reaction_10091745", "reaction_10068844", "reaction_10068699" ] }, "R-BTA-5687128": { "id": "pathway_10094602", "reactome": "R-BTA-5687128", "name": "MAPK6/MAPK4 signaling", "reactions": [ "reaction_10075251", "reaction_10075253", "reaction_10076229", "reaction_10075256", "reaction_10075916", "reaction_10075906", "reaction_10075205", "reaction_10076198", "reaction_10075260", "reaction_10075223", "reaction_10076193", "reaction_10075218", "reaction_10075239", "reaction_10075262" ] }, "R-BTA-9707616": { "id": "pathway_10093890", "reactome": "R-BTA-9707616", "name": "Heme signaling", "reactions": [ "reaction_10092237", "reaction_10052914", "reaction_10092271", "reaction_10092227", "reaction_10092269", "reaction_10092225", "reaction_10092239", "reaction_10092214" ] }, "R-BTA-6804754": { "id": "pathway_10094688", "reactome": "R-BTA-6804754", "name": "Regulation of TP53 Expression", "reactions": [ "reaction_10081561" ] }, "R-BTA-157579": { "id": "pathway_10092964", "reactome": "R-BTA-157579", "name": "Telomere Maintenance", "reactions": [ "reaction_10038947", "reaction_10091663", "reaction_10038540", "reaction_10091685", "reaction_10038949", "reaction_10038534" ] }, "R-BTA-5666185": { "id": "pathway_10094556", "reactome": "R-BTA-5666185", "name": "RHO GTPases Activate Rhotekin and Rhophilins", "reactions": [ "reaction_10073577" ] }, "R-BTA-109704": { "id": "pathway_10092734", "reactome": "R-BTA-109704", "name": "PI3K Cascade", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10036570", "reaction_10036607" ] }, "R-BTA-8948216": { "id": "pathway_10094194", "reactome": "R-BTA-8948216", "name": "Collagen chain trimerization", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10087581", "reaction_10087567", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10062071", "reaction_10087569", "reaction_10087585", "reaction_10087565", "reaction_10087573", "reaction_10087579" ] }, "R-BTA-1170546": { "id": "pathway_10093936", "reactome": "R-BTA-1170546", "name": "Prolactin receptor signaling", "reactions": [ "reaction_10054524", "reaction_10056335", "reaction_10060412", "reaction_10057823", "reaction_10057836", "reaction_10054791", "reaction_10057834" ] }, "R-BTA-167826": { "id": "pathway_10093008", "reactome": "R-BTA-167826", "name": "The fatty acid cycling model", "reactions": [ "reaction_10039254", "reaction_10039240", "reaction_10039242" ] }, "R-BTA-419771": { "id": "pathway_10093694", "reactome": "R-BTA-419771", "name": "Opsins", "reactions": [ "reaction_10048208", "reaction_10048214" ] }, "R-BTA-350054": { "id": "pathway_10093444", "reactome": "R-BTA-350054", "name": "Notch-HLH transcription pathway", "reactions": [ "reaction_10044446", "reaction_10044726" ] }, "R-BTA-9708530": { "id": "pathway_10095040", "reactome": "R-BTA-9708530", "name": "Regulation of BACH1 activity", "reactions": [ "reaction_10092289", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10092239" ] }, "R-BTA-1299308": { "id": "pathway_10094054", "reactome": "R-BTA-1299308", "name": "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)", "reactions": [ "reaction_10057639" ] }, "R-BTA-72766": { "id": "pathway_10092570", "reactome": "R-BTA-72766", "name": "Translation", "reactions": [ "reaction_10038107", "reaction_10050169", "reaction_10034855", "reaction_10038082", "reaction_10034365", "reaction_10034383", "reaction_10034224", "reaction_10034387", "reaction_10060894", "reaction_10034905" ] }, "R-BTA-936964": { "id": "pathway_10093074", "reactome": "R-BTA-936964", "name": "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon", "reactions": [ "reaction_10040197", "reaction_10039560" ] }, "R-BTA-77350": { "id": "pathway_10092712", "reactome": "R-BTA-77350", "name": "Beta oxidation of hexanoyl-CoA to butanoyl-CoA", "reactions": [ "reaction_10036027" ] }, "R-BTA-2187335": { "id": "pathway_10094294", "reactome": "R-BTA-2187335", "name": "The retinoid cycle in cones (daylight vision)", "reactions": [ "reaction_10065677", "reaction_10065683", "reaction_10065664", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065673", "reaction_10065679", "reaction_10065675" ] }, "R-BTA-1679131": { "id": "pathway_10094162", "reactome": "R-BTA-1679131", "name": "Trafficking and processing of endosomal TLR", "reactions": [ "reaction_10060773", "reaction_10060759", "reaction_10060783", "reaction_10060785" ] }, "R-BTA-2559582": { "id": "pathway_10093142", "reactome": "R-BTA-2559582", "name": "Senescence-Associated Secretory Phenotype (SASP)", "reactions": [ "reaction_10040355", "reaction_10041950", "reaction_10068899" ] }, "R-BTA-1483115": { "id": "pathway_10094100", "reactome": "R-BTA-1483115", "name": "Hydrolysis of LPC", "reactions": [ "reaction_10058910", "reaction_10088026", "reaction_10058871" ] }, "R-BTA-5654699": { "id": "pathway_10094526", "reactome": "R-BTA-5654699", "name": "SHC-mediated cascade:FGFR2", "reactions": [ "reaction_10072999", "reaction_10073001", "reaction_10072993", "reaction_10073004" ] }, "R-BTA-5654736": { "id": "pathway_10093174", "reactome": "R-BTA-5654736", "name": "Signaling by FGFR1", "reactions": [ "reaction_10073326", "reaction_10073083", "reaction_10057327", "reaction_10073090", "reaction_10073108", "reaction_10072935", "reaction_10073106", "reaction_10073113", "reaction_10072920", "reaction_10073225", "reaction_10073087", "reaction_10073077", "reaction_10057314", "reaction_10057329", "reaction_10073122", "reaction_10073199", "reaction_10059156", "reaction_10040696", "reaction_10053082", "reaction_10073115", "reaction_10057318", "reaction_10040704", "reaction_10073228", "reaction_10087373", "reaction_10040794", "reaction_10073102", "reaction_10072957", "reaction_10040773", "reaction_10073097", "reaction_10073119", "reaction_10073071", "reaction_10040791", "reaction_10072937", "reaction_10073201", "reaction_10057323", "reaction_10057337", "reaction_10040860", "reaction_10057302" ] }, "R-BTA-1660661": { "id": "pathway_10093726", "reactome": "R-BTA-1660661", "name": "Sphingolipid de novo biosynthesis", "reactions": [ "reaction_10049182", "reaction_10048860", "reaction_10049154", "reaction_10076389", "reaction_10082058", "reaction_10049163", "reaction_10048986", "reaction_10048910", "reaction_10049161", "reaction_10049121", "reaction_10091936", "reaction_10048995", "reaction_10049116", "reaction_10048917", "reaction_10048889", "reaction_10049141", "reaction_10049004", "reaction_10049189", "reaction_10091941", "reaction_10048988", "reaction_10076833", "reaction_10049007", "reaction_10048903", "reaction_10048882", "reaction_10049143", "reaction_10048978", "reaction_10076151", "reaction_10048896" ] }, "R-BTA-5654219": { "id": "pathway_10094514", "reactome": "R-BTA-5654219", "name": "Phospholipase C-mediated cascade: FGFR1", "reactions": [ "reaction_10072920", "reaction_10072937", "reaction_10072935" ] }, "R-BTA-9037629": { "id": "pathway_10094972", "reactome": "R-BTA-9037629", "name": "Lewis blood group biosynthesis", "reactions": [ "reaction_10090799", "reaction_10090774", "reaction_10090867", "reaction_10090822", "reaction_10090797", "reaction_10090854", "reaction_10090772", "reaction_10090856", "reaction_10090851", "reaction_10090819", "reaction_10090802" ] }, "R-BTA-1433559": { "id": "pathway_10093396", "reactome": "R-BTA-1433559", "name": "Regulation of KIT signaling", "reactions": [ "reaction_10057867", "reaction_10043832" ] }, "R-BTA-1237044": { "id": "pathway_10094002", "reactome": "R-BTA-1237044", "name": "Erythrocytes take up carbon dioxide and release oxygen", "reactions": [ "reaction_10058790", "reaction_10057007", "reaction_10081968", "reaction_10057062" ] }, "R-BTA-70221": { "id": "pathway_10092470", "reactome": "R-BTA-70221", "name": "Glycogen breakdown (glycogenolysis)", "reactions": [ "reaction_10034118", "reaction_10034138", "reaction_10090696", "reaction_10033594", "reaction_10050637" ] }, "R-BTA-111448": { "id": "pathway_10092864", "reactome": "R-BTA-111448", "name": "Activation of NOXA and translocation to mitochondria", "reactions": [ "reaction_10037739" ] }, "R-BTA-9706369": { "id": "pathway_10095030", "reactome": "R-BTA-9706369", "name": "Negative regulation of FLT3", "reactions": [ "reaction_10092143", "reaction_10092147", "reaction_10092195", "reaction_10092183", "reaction_10092139", "reaction_10092173", "reaction_10092040", "reaction_10092141", "reaction_10092126" ] }, "R-BTA-195721": { "id": "pathway_10093272", "reactome": "R-BTA-195721", "name": "Signaling by WNT", "reactions": [ "reaction_10067128", "reaction_10069459", "reaction_10067124", "reaction_10069448", "reaction_10068078", "reaction_10068073", "reaction_10069882", "reaction_10068704", "reaction_10069896", "reaction_10069645", "reaction_10041637", "reaction_10067879", "reaction_10067694", "reaction_10069664", "reaction_10067698", "reaction_10063849", "reaction_10071356", "reaction_10068088", "reaction_10069876", "reaction_10041629", "reaction_10071320", "reaction_10068707", "reaction_10070931", "reaction_10066994", "reaction_10069607", "reaction_10087597", "reaction_10069595", "reaction_10041583", "reaction_10069647", "reaction_10068933", "reaction_10041604", "reaction_10068939", "reaction_10069593", "reaction_10068839", "reaction_10069299", "reaction_10068086", "reaction_10068837", "reaction_10063843", "reaction_10069651", "reaction_10069872", "reaction_10067204", "reaction_10041640", "reaction_10069456", "reaction_10071330", "reaction_10041647", "reaction_10068923", "reaction_10068095", "reaction_10067696", "reaction_10059152", "reaction_10067200", "reaction_10041606", "reaction_10067202", "reaction_10043129" ] }, "R-BTA-5218920": { "id": "pathway_10094278", "reactome": "R-BTA-5218920", "name": "VEGFR2 mediated vascular permeability", "reactions": [ "reaction_10065227" ] }, "R-BTA-438064": { "id": "pathway_10092796", "reactome": "R-BTA-438064", "name": "Post NMDA receptor activation events", "reactions": [ "reaction_10090547", "reaction_10091067", "reaction_10049478", "reaction_10091075", "reaction_10036981" ] }, "R-BTA-8853383": { "id": "pathway_10094676", "reactome": "R-BTA-8853383", "name": "Lysosomal oligosaccharide catabolism", "reactions": [ "reaction_10080747", "reaction_10084129", "reaction_10080756" ] }, "R-BTA-1482798": { "id": "pathway_10094106", "reactome": "R-BTA-1482798", "name": "Acyl chain remodeling of CL", "reactions": [ "reaction_10058998", "reaction_10058985", "reaction_10058993", "reaction_10058955" ] }, "R-BTA-112303": { "id": "pathway_10093516", "reactome": "R-BTA-112303", "name": "Electric Transmission Across Gap Junctions", "reactions": [ "reaction_10045444", "reaction_10045455", "reaction_10045466" ] }, "R-BTA-380972": { "id": "pathway_10093544", "reactome": "R-BTA-380972", "name": "Energy dependent regulation of mTOR by LKB1-AMPK", "reactions": [ "reaction_10046572", "reaction_10046583", "reaction_10049894", "reaction_10046588" ] }, "R-BTA-168138": { "id": "pathway_10093028", "reactome": "R-BTA-168138", "name": "Toll Like Receptor 9 (TLR9) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-8854214": { "id": "pathway_10094764", "reactome": "R-BTA-8854214", "name": "TBC/RABGAPs", "reactions": [ "reaction_10084238", "reaction_10084291", "reaction_10084276", "reaction_10084246", "reaction_10084261", "reaction_10084228" ] }, "R-BTA-111957": { "id": "pathway_10092806", "reactome": "R-BTA-111957", "name": "Cam-PDE 1 activation", "reactions": [ "reaction_10037022", "reaction_10037024" ] }, "R-BTA-389887": { "id": "pathway_10093594", "reactome": "R-BTA-389887", "name": "Beta-oxidation of pristanoyl-CoA", "reactions": [ "reaction_10047044", "reaction_10047042", "reaction_10047056", "reaction_10047033" ] }, "R-BTA-351143": { "id": "pathway_10093472", "reactome": "R-BTA-351143", "name": "Agmatine biosynthesis", "reactions": [ "reaction_10044801" ] }, "R-BTA-211897": { "id": "pathway_10092692", "reactome": "R-BTA-211897", "name": "Cytochrome P450 - arranged by substrate type", "reactions": [ "reaction_10044477", "reaction_10041177", "reaction_10043971", "reaction_10041412", "reaction_10044235", "reaction_10041386", "reaction_10035958", "reaction_10044182", "reaction_10044255", "reaction_10044242", "reaction_10044280", "reaction_10041415", "reaction_10044250", "reaction_10044223", "reaction_10044275", "reaction_10044204", "reaction_10035977", "reaction_10035878", "reaction_10044216", "reaction_10044225", "reaction_10044265", "reaction_10035911", "reaction_10041397", "reaction_10044167", "reaction_10071909", "reaction_10044247", "reaction_10044195", "reaction_10077751", "reaction_10035865", "reaction_10044218", "reaction_10043964", "reaction_10041393", "reaction_10041193", "reaction_10044151", "reaction_10044270", "reaction_10041277", "reaction_10044211", "reaction_10044480", "reaction_10044158", "reaction_10041500", "reaction_10041217", "reaction_10041206", "reaction_10044260", "reaction_10044232", "reaction_10044293", "reaction_10035861", "reaction_10041195" ] }, "R-BTA-975634": { "id": "pathway_10093924", "reactome": "R-BTA-975634", "name": "Retinoid metabolism and transport", "reactions": [ "reaction_10054382", "reaction_10065445", "reaction_10069948", "reaction_10054404", "reaction_10066249", "reaction_10065437", "reaction_10066247", "reaction_10054393", "reaction_10065441", "reaction_10054375", "reaction_10070971", "reaction_10054395" ] }, "R-BTA-141333": { "id": "pathway_10092888", "reactome": "R-BTA-141333", "name": "Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB", "reactions": [ "reaction_10038000" ] }, "R-BTA-190372": { "id": "pathway_10093188", "reactome": "R-BTA-190372", "name": "FGFR3c ligand binding and activation", "reactions": [ "reaction_10083933", "reaction_10040782", "reaction_10083935", "reaction_10040753" ] }, "R-BTA-1483213": { "id": "pathway_10094108", "reactome": "R-BTA-1483213", "name": "Synthesis of PE", "reactions": [ "reaction_10059130", "reaction_10059141", "reaction_10059082", "reaction_10076994", "reaction_10059150", "reaction_10059035" ] }, "R-BTA-1482883": { "id": "pathway_10094096", "reactome": "R-BTA-1482883", "name": "Acyl chain remodeling of DAG and TAG", "reactions": [ "reaction_10058892", "reaction_10058819", "reaction_10058948", "reaction_10059006", "reaction_10077004", "reaction_10058894", "reaction_10058961", "reaction_10083572" ] }, "R-BTA-163680": { "id": "pathway_10092988", "reactome": "R-BTA-163680", "name": "AMPK inhibits chREBP transcriptional activation activity", "reactions": [ "reaction_10083614", "reaction_10038938" ] }, "R-BTA-74752": { "id": "pathway_10092644", "reactome": "R-BTA-74752", "name": "Signaling by Insulin receptor", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10035536", "reaction_10036570", "reaction_10075097", "reaction_10035507", "reaction_10036607", "reaction_10036616", "reaction_10075065" ] }, "R-BTA-2025928": { "id": "pathway_10095022", "reactome": "R-BTA-2025928", "name": "Calcineurin activates NFAT", "reactions": [ "reaction_10091817" ] }, "R-BTA-9014826": { "id": "pathway_10094730", "reactome": "R-BTA-9014826", "name": "Interleukin-36 pathway", "reactions": [ "reaction_10087338", "reaction_10083522" ] }, "R-BTA-500657": { "id": "pathway_10093826", "reactome": "R-BTA-500657", "name": "Presynaptic function of Kainate receptors", "reactions": [ "reaction_10051085" ] }, "R-BTA-202670": { "id": "pathway_10093322", "reactome": "R-BTA-202670", "name": "ERKs are inactivated", "reactions": [ "reaction_10042826", "reaction_10043488" ] }, "R-BTA-1660517": { "id": "pathway_10094152", "reactome": "R-BTA-1660517", "name": "Synthesis of PIPs at the late endosome membrane", "reactions": [ "reaction_10060537", "reaction_10060468", "reaction_10060553" ] }, "R-BTA-1266695": { "id": "pathway_10094792", "reactome": "R-BTA-1266695", "name": "Interleukin-7 signaling", "reactions": [ "reaction_10089253", "reaction_10085017", "reaction_10089251", "reaction_10091731" ] }, "R-BTA-420092": { "id": "pathway_10092982", "reactome": "R-BTA-420092", "name": "Glucagon-type ligand receptors", "reactions": [ "reaction_10048304", "reaction_10048248", "reaction_10038918", "reaction_10048282" ] }, "R-BTA-1251985": { "id": "pathway_10094020", "reactome": "R-BTA-1251985", "name": "Nuclear signaling by ERBB4", "reactions": [ "reaction_10057236", "reaction_10057286", "reaction_10057298", "reaction_10057272", "reaction_10057284", "reaction_10057252" ] }, "R-BTA-422475": { "id": "pathway_10093384", "reactome": "R-BTA-422475", "name": "Axon guidance", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10084393", "reaction_10084185", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-2682334": { "id": "pathway_10094388", "reactome": "R-BTA-2682334", "name": "EPH-Ephrin signaling", "reactions": [ "reaction_10069285", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10069146", "reaction_10069418", "reaction_10069131", "reaction_10069192", "reaction_10069253", "reaction_10069121", "reaction_10069144", "reaction_10069188", "reaction_10069221", "reaction_10069435", "reaction_10069226", "reaction_10069159", "reaction_10069157", "reaction_10069223" ] }, "R-BTA-75893": { "id": "pathway_10092880", "reactome": "R-BTA-75893", "name": "TNF signaling", "reactions": [ "reaction_10071556", "reaction_10071524", "reaction_10071526", "reaction_10092031", "reaction_10071541", "reaction_10071534", "reaction_10067895", "reaction_10084723", "reaction_10037964", "reaction_10092026", "reaction_10067908" ] }, "R-BTA-3214841": { "id": "pathway_10094410", "reactome": "R-BTA-3214841", "name": "PKMTs methylate histone lysines", "reactions": [ "reaction_10072790", "reaction_10070962", "reaction_10069846", "reaction_10072788", "reaction_10072655", "reaction_10069838", "reaction_10072778", "reaction_10072823", "reaction_10069939", "reaction_10072813", "reaction_10072755", "reaction_10072752", "reaction_10069937", "reaction_10072750", "reaction_10072725" ] }, "R-BTA-888593": { "id": "pathway_10093486", "reactome": "R-BTA-888593", "name": "Reuptake of GABA", "reactions": [ "reaction_10044941", "reaction_10049583" ] }, "R-BTA-195258": { "id": "pathway_10093366", "reactome": "R-BTA-195258", "name": "RHO GTPase Effectors", "reactions": [ "reaction_10091169", "reaction_10073549", "reaction_10091180", "reaction_10073796", "reaction_10073716", "reaction_10073806", "reaction_10073507", "reaction_10063374", "reaction_10073842", "reaction_10072515", "reaction_10073503", "reaction_10073557", "reaction_10063353", "reaction_10073755", "reaction_10073525", "reaction_10073547", "reaction_10068933", "reaction_10068939", "reaction_10073493", "reaction_10073577", "reaction_10073731", "reaction_10073569", "reaction_10073561", "reaction_10091175", "reaction_10043461", "reaction_10073559" ] }, "R-BTA-110362": { "id": "pathway_10094848", "reactome": "R-BTA-110362", "name": "POLB-Dependent Long Patch Base Excision Repair", "reactions": [ "reaction_10088526" ] }, "R-BTA-418457": { "id": "pathway_10093678", "reactome": "R-BTA-418457", "name": "cGMP effects", "reactions": [ "reaction_10047930" ] }, "R-BTA-111447": { "id": "pathway_10092856", "reactome": "R-BTA-111447", "name": "Activation of BAD and translocation to mitochondria ", "reactions": [ "reaction_10037630", "reaction_10037674", "reaction_10037678" ] }, "R-BTA-418359": { "id": "pathway_10093664", "reactome": "R-BTA-418359", "name": "Reduction of cytosolic Ca++ levels", "reactions": [ "reaction_10047893", "reaction_10048504", "reaction_10047900" ] }, "R-BTA-114508": { "id": "pathway_10093704", "reactome": "R-BTA-114508", "name": "Effects of PIP2 hydrolysis", "reactions": [ "reaction_10076743", "reaction_10048580", "reaction_10048543", "reaction_10048587", "reaction_10048632", "reaction_10048660" ] }, "R-BTA-936440": { "id": "pathway_10093914", "reactome": "R-BTA-936440", "name": "Negative regulators of DDX58/IFIH1 signaling", "reactions": [ "reaction_10053122", "reaction_10053095", "reaction_10053134" ] }, "R-BTA-8939902": { "id": "pathway_10094824", "reactome": "R-BTA-8939902", "name": "Regulation of RUNX2 expression and activity", "reactions": [ "reaction_10089681", "reaction_10089679", "reaction_10086716", "reaction_10086724" ] }, "R-BTA-8851680": { "id": "pathway_10094750", "reactome": "R-BTA-8851680", "name": "Butyrophilin (BTN) family interactions", "reactions": [ "reaction_10083959", "reaction_10083967" ] }, "R-BTA-1483206": { "id": "pathway_10092668", "reactome": "R-BTA-1483206", "name": "Glycerophospholipid biosynthesis", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10035786", "reaction_10058913", "reaction_10085808", "reaction_10058998", "reaction_10085798", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10084526", "reaction_10071344", "reaction_10059035", "reaction_10058996", "reaction_10058970", "reaction_10059018", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10058834", "reaction_10085340", "reaction_10058874", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10059073", "reaction_10059114", "reaction_10058892", "reaction_10059014", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10085024", "reaction_10058899", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10086064", "reaction_10058980", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10058841", "reaction_10059026", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10059101", "reaction_10058948", "reaction_10058985", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10076824" ] }, "R-BTA-9619665": { "id": "pathway_10094980", "reactome": "R-BTA-9619665", "name": "EGR2 and SOX10-mediated initiation of Schwann cell myelination", "reactions": [ "reaction_10091007", "reaction_10091009" ] }, "R-BTA-1296061": { "id": "pathway_10094032", "reactome": "R-BTA-1296061", "name": "HCN channels", "reactions": [ "reaction_10057390", "reaction_10057607" ] }, "R-BTA-8866652": { "id": "pathway_10094752", "reactome": "R-BTA-8866652", "name": "Synthesis of active ubiquitin: roles of E1 and E2 enzymes", "reactions": [ "reaction_10084122", "reaction_10084008", "reaction_10084113", "reaction_10084117" ] }, "R-BTA-2428933": { "id": "pathway_10094594", "reactome": "R-BTA-2428933", "name": "SHC-related events triggered by IGF1R", "reactions": [ "reaction_10075063" ] }, "R-BTA-166016": { "id": "pathway_10093000", "reactome": "R-BTA-166016", "name": "Toll Like Receptor 4 (TLR4) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10039560", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10039217", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-211163": { "id": "pathway_10093424", "reactome": "R-BTA-211163", "name": "AKT-mediated inactivation of FOXO1A", "reactions": [ "reaction_10044090" ] }, "R-BTA-433137": { "id": "pathway_10093754", "reactome": "R-BTA-433137", "name": "Sodium-coupled sulphate, di- and tri-carboxylate transporters", "reactions": [ "reaction_10049326", "reaction_10049333" ] }, "R-BTA-389357": { "id": "pathway_10093582", "reactome": "R-BTA-389357", "name": "CD28 dependent PI3K/Akt signaling", "reactions": [ "reaction_10065227", "reaction_10046932", "reaction_10047530" ] }, "R-BTA-549132": { "id": "pathway_10093832", "reactome": "R-BTA-549132", "name": "Organic cation/anion/zwitterion transport", "reactions": [ "reaction_10051305", "reaction_10051314", "reaction_10051283", "reaction_10051307", "reaction_10051325", "reaction_10051286", "reaction_10051269", "reaction_10051276" ] }, "R-BTA-9020933": { "id": "pathway_10093782", "reactome": "R-BTA-9020933", "name": "Interleukin-23 signaling", "reactions": [ "reaction_10049928", "reaction_10088498", "reaction_10087789", "reaction_10087697" ] }, "R-BTA-2454202": { "id": "pathway_10093050", "reactome": "R-BTA-2454202", "name": "Fc epsilon receptor (FCERI) signaling", "reactions": [ "reaction_10066151", "reaction_10066059", "reaction_10066144", "reaction_10066102", "reaction_10066080", "reaction_10050208", "reaction_10066052", "reaction_10066094", "reaction_10066141", "reaction_10039508", "reaction_10066147", "reaction_10050256", "reaction_10043225", "reaction_10066120", "reaction_10066172", "reaction_10065642", "reaction_10066065", "reaction_10043182", "reaction_10066168", "reaction_10066082", "reaction_10066127", "reaction_10065491", "reaction_10066180" ] }, "R-BTA-8953897": { "id": "pathway_10092556", "reactome": "R-BTA-8953897", "name": "Cellular responses to external stimuli", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10073468", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10073460", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10073446", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10073481", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273", "reaction_10073464" ] }, "R-BTA-2046104": { "id": "pathway_10094218", "reactome": "R-BTA-2046104", "name": "alpha-linolenic (omega3) and linoleic (omega6) acid metabolism", "reactions": [ "reaction_10063440", "reaction_10063450", "reaction_10063454", "reaction_10063413", "reaction_10063456", "reaction_10063442", "reaction_10063570", "reaction_10063446", "reaction_10063448", "reaction_10063428", "reaction_10063430", "reaction_10063437", "reaction_10063420", "reaction_10063444", "reaction_10063425", "reaction_10063452", "reaction_10063573" ] }, "R-BTA-991365": { "id": "pathway_10093094", "reactome": "R-BTA-991365", "name": "Activation of GABAB receptors", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-446193": { "id": "pathway_10093224", "reactome": "R-BTA-446193", "name": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein", "reactions": [ "reaction_10069371", "reaction_10077823", "reaction_10082941", "reaction_10069320", "reaction_10049797", "reaction_10069359", "reaction_10049860", "reaction_10069357", "reaction_10049789", "reaction_10081490", "reaction_10049818", "reaction_10049811", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10049867", "reaction_10069368", "reaction_10040933", "reaction_10069373", "reaction_10049858", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10077826", "reaction_10049831", "reaction_10049851", "reaction_10049778", "reaction_10081497", "reaction_10069348", "reaction_10049844", "reaction_10050153", "reaction_10048958", "reaction_10077816", "reaction_10069382" ] }, "R-BTA-5685939": { "id": "pathway_10094606", "reactome": "R-BTA-5685939", "name": "HDR through MMEJ (alt-NHEJ)", "reactions": [ "reaction_10075306", "reaction_10075326", "reaction_10075304", "reaction_10075323", "reaction_10075319" ] }, "R-BTA-8981373": { "id": "pathway_10094808", "reactome": "R-BTA-8981373", "name": "Intestinal hexose absorption", "reactions": [ "reaction_10086350" ] }, "R-BTA-2467813": { "id": "pathway_10094296", "reactome": "R-BTA-2467813", "name": "Separation of Sister Chromatids", "reactions": [ "reaction_10065708", "reaction_10065726" ] }, "R-BTA-1296065": { "id": "pathway_10094026", "reactome": "R-BTA-1296065", "name": "Inwardly rectifying K+ channels", "reactions": [ "reaction_10057399", "reaction_10057350", "reaction_10057418" ] }, "R-BTA-69017": { "id": "pathway_10092416", "reactome": "R-BTA-69017", "name": "CDK-mediated phosphorylation and removal of Cdc6", "reactions": [ "reaction_10033473" ] }, "R-BTA-194313": { "id": "pathway_10093264", "reactome": "R-BTA-194313", "name": "VEGF ligand-receptor interactions", "reactions": [ "reaction_10041463", "reaction_10041649", "reaction_10041453" ] }, "R-BTA-166658": { "id": "pathway_10093022", "reactome": "R-BTA-166658", "name": "Complement cascade", "reactions": [ "reaction_10054736", "reaction_10039465", "reaction_10054649", "reaction_10054494", "reaction_10055971", "reaction_10084020", "reaction_10087797", "reaction_10039778", "reaction_10066238", "reaction_10090400", "reaction_10039782", "reaction_10054678" ] }, "R-BTA-397795": { "id": "pathway_10093360", "reactome": "R-BTA-397795", "name": "G-protein beta:gamma signalling", "reactions": [ "reaction_10047498", "reaction_10088962", "reaction_10043315" ] }, "R-BTA-73943": { "id": "pathway_10094774", "reactome": "R-BTA-73943", "name": "Reversal of alkylation damage by DNA dioxygenases", "reactions": [ "reaction_10084497" ] }, "R-BTA-8877627": { "id": "pathway_10094796", "reactome": "R-BTA-8877627", "name": "Vitamin E", "reactions": [ "reaction_10085855", "reaction_10085853" ] }, "R-BTA-450341": { "id": "pathway_10093056", "reactome": "R-BTA-450341", "name": "Activation of the AP-1 family of transcription factors", "reactions": [ "reaction_10050208", "reaction_10039508" ] }, "R-BTA-2132295": { "id": "pathway_10094224", "reactome": "R-BTA-2132295", "name": "MHC class II antigen presentation", "reactions": [ "reaction_10065011", "reaction_10064118", "reaction_10065009", "reaction_10064219", "reaction_10065051", "reaction_10065055", "reaction_10064214", "reaction_10063972", "reaction_10065019", "reaction_10084401", "reaction_10064277", "reaction_10064221", "reaction_10064068", "reaction_10065021" ] }, "R-BTA-5576894": { "id": "pathway_10094460", "reactome": "R-BTA-5576894", "name": "Phase 1 - inactivation of fast Na+ channels", "reactions": [ "reaction_10071819" ] }, "R-BTA-5690714": { "id": "pathway_10094614", "reactome": "R-BTA-5690714", "name": "CD22 mediated BCR regulation", "reactions": [ "reaction_10075923" ] }, "R-BTA-448706": { "id": "pathway_10093790", "reactome": "R-BTA-448706", "name": "Interleukin-1 processing", "reactions": [ "reaction_10050011", "reaction_10050028", "reaction_10050024" ] }, "R-BTA-3928664": { "id": "pathway_10094394", "reactome": "R-BTA-3928664", "name": "Ephrin signaling", "reactions": [ "reaction_10069418", "reaction_10069192", "reaction_10069188", "reaction_10069221", "reaction_10069226", "reaction_10069223" ] }, "R-BTA-5173105": { "id": "pathway_10093886", "reactome": "R-BTA-5173105", "name": "O-linked glycosylation", "reactions": [ "reaction_10052546", "reaction_10052690", "reaction_10054550", "reaction_10070145", "reaction_10076773", "reaction_10077688", "reaction_10054766", "reaction_10061538", "reaction_10052521", "reaction_10052665", "reaction_10052606", "reaction_10052496", "reaction_10054722", "reaction_10054575", "reaction_10054773", "reaction_10052716", "reaction_10052461" ] }, "R-BTA-196757": { "id": "pathway_10093294", "reactome": "R-BTA-196757", "name": "Metabolism of folate and pterines", "reactions": [ "reaction_10042936", "reaction_10042922", "reaction_10041838", "reaction_10082078", "reaction_10081339", "reaction_10092306", "reaction_10041840", "reaction_10082068", "reaction_10081346", "reaction_10081349", "reaction_10086763", "reaction_10042940", "reaction_10076485", "reaction_10087442", "reaction_10042929" ] }, "R-BTA-381771": { "id": "pathway_10093560", "reactome": "R-BTA-381771", "name": "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)", "reactions": [ "reaction_10046723", "reaction_10048380" ] }, "R-BTA-9018683": { "id": "pathway_10094928", "reactome": "R-BTA-9018683", "name": "Biosynthesis of DPA-derived SPMs", "reactions": [ "reaction_10090474", "reaction_10090466", "reaction_10090477", "reaction_10090470", "reaction_10090472", "reaction_10090468" ] }, "R-BTA-917977": { "id": "pathway_10093888", "reactome": "R-BTA-917977", "name": "Transferrin endocytosis and recycling", "reactions": [ "reaction_10052907", "reaction_10076099", "reaction_10052901", "reaction_10052888", "reaction_10052909", "reaction_10052925", "reaction_10052911", "reaction_10052923" ] }, "R-BTA-417973": { "id": "pathway_10093682", "reactome": "R-BTA-417973", "name": "Adenosine P1 receptors", "reactions": [ "reaction_10048003", "reaction_10047987" ] }, "R-BTA-444821": { "id": "pathway_10093774", "reactome": "R-BTA-444821", "name": "Relaxin receptors", "reactions": [ "reaction_10049699", "reaction_10049683" ] }, "R-BTA-77588": { "id": "pathway_10092718", "reactome": "R-BTA-77588", "name": "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs", "reactions": [ "reaction_10036052", "reaction_10036076", "reaction_10036080" ] }, "R-BTA-9705462": { "id": "pathway_10095032", "reactome": "R-BTA-9705462", "name": "Inactivation of CSF3 (G-CSF) signaling", "reactions": [ "reaction_10092257", "reaction_10092108" ] }, "R-BTA-427601": { "id": "pathway_10093718", "reactome": "R-BTA-427601", "name": "Multifunctional anion exchangers", "reactions": [ "reaction_10048727", "reaction_10048768", "reaction_10048740", "reaction_10085967" ] }, "R-BTA-8963691": { "id": "pathway_10092538", "reactome": "R-BTA-8963691", "name": "Phenylalanine and tyrosine metabolism", "reactions": [ "reaction_10064346", "reaction_10033944", "reaction_10033935", "reaction_10033962", "reaction_10076974", "reaction_10033953", "reaction_10052040" ] }, "R-BTA-5686938": { "id": "pathway_10094686", "reactome": "R-BTA-5686938", "name": "Regulation of TLR by endogenous ligand", "reactions": [ "reaction_10081905", "reaction_10085369", "reaction_10081506", "reaction_10081510" ] }, "R-BTA-5685938": { "id": "pathway_10092676", "reactome": "R-BTA-5685938", "name": "HDR through Single Strand Annealing (SSA)", "reactions": [ "reaction_10075181", "reaction_10035846" ] }, "R-BTA-5654726": { "id": "pathway_10093910", "reactome": "R-BTA-5654726", "name": "Negative regulation of FGFR1 signaling", "reactions": [ "reaction_10059156", "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10073201", "reaction_10073199", "reaction_10057323", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-69239": { "id": "pathway_10092420", "reactome": "R-BTA-69239", "name": "Synthesis of DNA", "reactions": [ "reaction_10033473", "reaction_10033504", "reaction_10040183" ] }, "R-BTA-163316": { "id": "pathway_10092974", "reactome": "R-BTA-163316", "name": "Mitochondrial transcription termination", "reactions": [ "reaction_10038904" ] }, "R-BTA-190861": { "id": "pathway_10093206", "reactome": "R-BTA-190861", "name": "Gap junction assembly", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040842", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-983189": { "id": "pathway_10093946", "reactome": "R-BTA-983189", "name": "Kinesins", "reactions": [ "reaction_10055515", "reaction_10055829", "reaction_10055647", "reaction_10055645", "reaction_10055831", "reaction_10055827", "reaction_10055823", "reaction_10055833" ] }, "R-BTA-9018681": { "id": "pathway_10094914", "reactome": "R-BTA-9018681", "name": "Biosynthesis of protectins", "reactions": [ "reaction_10090460", "reaction_10090708", "reaction_10090386" ] }, "R-BTA-8856825": { "id": "pathway_10094778", "reactome": "R-BTA-8856825", "name": "Cargo recognition for clathrin-mediated endocytosis", "reactions": [ "reaction_10084824", "reaction_10084757", "reaction_10091753", "reaction_10085134", "reaction_10084822", "reaction_10085264", "reaction_10084819", "reaction_10085166", "reaction_10085116" ] }, "R-BTA-1912422": { "id": "pathway_10094184", "reactome": "R-BTA-1912422", "name": "Pre-NOTCH Expression and Processing", "reactions": [ "reaction_10090409", "reaction_10061449" ] }, "R-BTA-74749": { "id": "pathway_10094596", "reactome": "R-BTA-74749", "name": "Signal attenuation", "reactions": [ "reaction_10075065", "reaction_10075097" ] }, "R-BTA-8981607": { "id": "pathway_10094866", "reactome": "R-BTA-8981607", "name": "Intracellular oxygen transport", "reactions": [ "reaction_10089060", "reaction_10089058", "reaction_10089048", "reaction_10089062" ] }, "R-BTA-68689": { "id": "pathway_10092396", "reactome": "R-BTA-68689", "name": "CDC6 association with the ORC:origin complex", "reactions": [ "reaction_10033379" ] }, "R-BTA-8863795": { "id": "pathway_10094070", "reactome": "R-BTA-8863795", "name": "Downregulation of ERBB2 signaling", "reactions": [ "reaction_10057712", "reaction_10057735", "reaction_10057740", "reaction_10057719", "reaction_10061458", "reaction_10057742", "reaction_10057744", "reaction_10084849" ] }, "R-BTA-1222556": { "id": "pathway_10093676", "reactome": "R-BTA-1222556", "name": "ROS and RNS production in phagocytes", "reactions": [ "reaction_10084322", "reaction_10056531", "reaction_10077924", "reaction_10077921", "reaction_10047907", "reaction_10086405", "reaction_10077926", "reaction_10077919", "reaction_10077904" ] }, "R-BTA-5357956": { "id": "pathway_10094446", "reactome": "R-BTA-5357956", "name": "TNFR1-induced NFkappaB signaling pathway", "reactions": [ "reaction_10071556", "reaction_10071524", "reaction_10071526" ] }, "R-BTA-69186": { "id": "pathway_10092426", "reactome": "R-BTA-69186", "name": "Lagging Strand Synthesis", "reactions": [ "reaction_10033504" ] }, "R-BTA-111997": { "id": "pathway_10092786", "reactome": "R-BTA-111997", "name": "CaM pathway", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-190370": { "id": "pathway_10093170", "reactome": "R-BTA-190370", "name": "FGFR1b ligand binding and activation", "reactions": [ "reaction_10040791", "reaction_10040696" ] }, "R-BTA-1236394": { "id": "pathway_10093990", "reactome": "R-BTA-1236394", "name": "Signaling by ERBB4", "reactions": [ "reaction_10057177", "reaction_10057175", "reaction_10057236", "reaction_10057286", "reaction_10057184", "reaction_10057166", "reaction_10057264", "reaction_10057272", "reaction_10056781", "reaction_10057191", "reaction_10057298", "reaction_10057284", "reaction_10057262", "reaction_10057252", "reaction_10057151", "reaction_10090971", "reaction_10057188" ] }, "R-BTA-196783": { "id": "pathway_10093282", "reactome": "R-BTA-196783", "name": "Coenzyme A biosynthesis", "reactions": [ "reaction_10041756", "reaction_10042655", "reaction_10041765", "reaction_10041744", "reaction_10041737" ] }, "R-BTA-425407": { "id": "pathway_10092730", "reactome": "R-BTA-425407", "name": "SLC-mediated transmembrane transport", "reactions": [ "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10049371", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10049319", "reaction_10045494", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10049080", "reaction_10044978", "reaction_10051892", "reaction_10085907", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10045501", "reaction_10049464", "reaction_10045473", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10048795", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10051547", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10044962", "reaction_10072522", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10048504", "reaction_10049440", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10049083", "reaction_10048768", "reaction_10049378", "reaction_10049869", "reaction_10044941", "reaction_10048491", "reaction_10051276", "reaction_10044934", "reaction_10089029", "reaction_10049385", "reaction_10051545", "reaction_10044955", "reaction_10085384", "reaction_10051587", "reaction_10048754", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10036297", "reaction_10071001", "reaction_10051879", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10049053", "reaction_10048821", "reaction_10049628", "reaction_10049447", "reaction_10071003", "reaction_10051866", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-8985947": { "id": "pathway_10094872", "reactome": "R-BTA-8985947", "name": "Interleukin-9 signaling", "reactions": [ "reaction_10089736", "reaction_10089363", "reaction_10091731" ] }, "R-BTA-2142670": { "id": "pathway_10094246", "reactome": "R-BTA-2142670", "name": "Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)", "reactions": [ "reaction_10064526", "reaction_10064521" ] }, "R-BTA-140834": { "id": "pathway_10092876", "reactome": "R-BTA-140834", "name": "Extrinsic Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10037913", "reaction_10037906", "reaction_10037937", "reaction_10037899", "reaction_10037887", "reaction_10037915", "reaction_10037895" ] }, "R-BTA-418360": { "id": "pathway_10092850", "reactome": "R-BTA-418360", "name": "Platelet calcium homeostasis", "reactions": [ "reaction_10048504", "reaction_10037607", "reaction_10047893", "reaction_10048635", "reaction_10047900" ] }, "R-BTA-140342": { "id": "pathway_10093430", "reactome": "R-BTA-140342", "name": "Apoptosis induced DNA fragmentation", "reactions": [ "reaction_10044142", "reaction_10044116", "reaction_10044680", "reaction_10044146", "reaction_10044144" ] }, "R-BTA-918233": { "id": "pathway_10093958", "reactome": "R-BTA-918233", "name": "TRAF3-dependent IRF activation pathway", "reactions": [ "reaction_10056084", "reaction_10056082", "reaction_10056090" ] }, "R-BTA-69275": { "id": "pathway_10093088", "reactome": "R-BTA-69275", "name": "G2/M Transition", "reactions": [ "reaction_10039612", "reaction_10084043", "reaction_10084051", "reaction_10039614", "reaction_10084102", "reaction_10065938", "reaction_10066489", "reaction_10084090", "reaction_10084216", "reaction_10084214", "reaction_10084047", "reaction_10084206", "reaction_10084096", "reaction_10066487", "reaction_10084028" ] }, "R-BTA-8949613": { "id": "pathway_10094834", "reactome": "R-BTA-8949613", "name": "Cristae formation", "reactions": [ "reaction_10087635" ] }, "R-BTA-5668541": { "id": "pathway_10094466", "reactome": "R-BTA-5668541", "name": "TNFR2 non-canonical NF-kB pathway", "reactions": [ "reaction_10073699", "reaction_10076165", "reaction_10074266", "reaction_10074312", "reaction_10073708", "reaction_10071948", "reaction_10074318", "reaction_10072030", "reaction_10071975", "reaction_10074340", "reaction_10071982", "reaction_10073757", "reaction_10076237", "reaction_10073690", "reaction_10074320", "reaction_10074308", "reaction_10074316", "reaction_10074306", "reaction_10074310", "reaction_10073765", "reaction_10074280", "reaction_10074314" ] }, "R-BTA-5578775": { "id": "pathway_10093666", "reactome": "R-BTA-5578775", "name": "Ion homeostasis", "reactions": [ "reaction_10048504", "reaction_10047893", "reaction_10053180", "reaction_10048787", "reaction_10091759" ] }, "R-BTA-964739": { "id": "pathway_10093920", "reactome": "R-BTA-964739", "name": "N-glycan trimming and elongation in the cis-Golgi", "reactions": [ "reaction_10053317", "reaction_10053331", "reaction_10053337", "reaction_10053339", "reaction_10053324" ] }, "R-BTA-180786": { "id": "pathway_10092962", "reactome": "R-BTA-180786", "name": "Extension of Telomeres", "reactions": [ "reaction_10038947", "reaction_10091663", "reaction_10038540", "reaction_10038949", "reaction_10038534" ] }, "R-BTA-977606": { "id": "pathway_10093934", "reactome": "R-BTA-977606", "name": "Regulation of Complement cascade", "reactions": [ "reaction_10054649", "reaction_10054494", "reaction_10055971", "reaction_10084020", "reaction_10087797", "reaction_10066238", "reaction_10090400", "reaction_10054678" ] }, "R-BTA-170670": { "id": "pathway_10093092", "reactome": "R-BTA-170670", "name": "Adenylate cyclase inhibitory pathway", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-888568": { "id": "pathway_10093878", "reactome": "R-BTA-888568", "name": "GABA synthesis", "reactions": [ "reaction_10052013", "reaction_10051999" ] }, "R-BTA-975956": { "id": "pathway_10093892", "reactome": "R-BTA-975956", "name": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "reactions": [ "reaction_10052963" ] }, "R-BTA-174143": { "id": "pathway_10092896", "reactome": "R-BTA-174143", "name": "APC/C-mediated degradation of cell cycle proteins", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-451927": { "id": "pathway_10093820", "reactome": "R-BTA-451927", "name": "Interleukin-2 family signaling", "reactions": [ "reaction_10089736", "reaction_10089267", "reaction_10051194", "reaction_10052343", "reaction_10089311", "reaction_10089269", "reaction_10050619", "reaction_10050623", "reaction_10051196", "reaction_10089291", "reaction_10091731", "reaction_10052254", "reaction_10050527", "reaction_10089363", "reaction_10052337" ] }, "R-BTA-8849932": { "id": "pathway_10094746", "reactome": "R-BTA-8849932", "name": "Synaptic adhesion-like molecules", "reactions": [ "reaction_10083793", "reaction_10083789", "reaction_10084356" ] }, "R-BTA-8878159": { "id": "pathway_10094790", "reactome": "R-BTA-8878159", "name": "Transcriptional regulation by RUNX3", "reactions": [ "reaction_10086587", "reaction_10088006", "reaction_10087910", "reaction_10086581", "reaction_10088012", "reaction_10087900", "reaction_10088490", "reaction_10084947", "reaction_10088482", "reaction_10087862", "reaction_10086231", "reaction_10087997", "reaction_10087889", "reaction_10086241", "reaction_10086589" ] }, "R-BTA-9009391": { "id": "pathway_10094994", "reactome": "R-BTA-9009391", "name": "Extra-nuclear estrogen signaling", "reactions": [ "reaction_10091151", "reaction_10091260", "reaction_10091275", "reaction_10091158", "reaction_10091118", "reaction_10091271", "reaction_10091115", "reaction_10091267", "reaction_10091156" ] }, "R-BTA-69541": { "id": "pathway_10092442", "reactome": "R-BTA-69541", "name": "Stabilization of p53", "reactions": [ "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-176187": { "id": "pathway_10093124", "reactome": "R-BTA-176187", "name": "Activation of ATR in response to replication stress", "reactions": [ "reaction_10040059" ] }, "R-BTA-199991": { "id": "pathway_10093212", "reactome": "R-BTA-199991", "name": "Membrane Trafficking", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10084261", "reaction_10086209", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10083342", "reaction_10083767", "reaction_10040961", "reaction_10076778", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-2534343": { "id": "pathway_10094306", "reactome": "R-BTA-2534343", "name": "Interaction With Cumulus Cells And The Zona Pellucida", "reactions": [ "reaction_10065827" ] }, "R-BTA-140179": { "id": "pathway_10092890", "reactome": "R-BTA-140179", "name": "Amine Oxidase reactions", "reactions": [ "reaction_10038000" ] }, "R-BTA-419408": { "id": "pathway_10093692", "reactome": "R-BTA-419408", "name": "Lysosphingolipid and LPA receptors", "reactions": [ "reaction_10078536", "reaction_10048176", "reaction_10048180" ] }, "R-BTA-8847993": { "id": "pathway_10094722", "reactome": "R-BTA-8847993", "name": "ERBB2 Activates PTK6 Signaling", "reactions": [ "reaction_10083483", "reaction_10083477" ] }, "R-BTA-8874211": { "id": "pathway_10094798", "reactome": "R-BTA-8874211", "name": "CREB3 factors activate genes", "reactions": [ "reaction_10085865" ] }, "R-BTA-69560": { "id": "pathway_10094684", "reactome": "R-BTA-69560", "name": "Transcriptional activation of p53 responsive genes ", "reactions": [ "reaction_10081470" ] }, "R-BTA-888590": { "id": "pathway_10093488", "reactome": "R-BTA-888590", "name": "GABA synthesis, release, reuptake and degradation", "reactions": [ "reaction_10052013", "reaction_10051999", "reaction_10052018", "reaction_10044941", "reaction_10051989", "reaction_10049583" ] }, "R-BTA-9036866": { "id": "pathway_10093148", "reactome": "R-BTA-9036866", "name": "Expression and Processing of Neurotrophins", "reactions": [ "reaction_10040489", "reaction_10040495" ] }, "R-BTA-202433": { "id": "pathway_10093356", "reactome": "R-BTA-202433", "name": "Generation of second messenger molecules", "reactions": [ "reaction_10043262", "reaction_10043241" ] }, "R-BTA-983705": { "id": "pathway_10093968", "reactome": "R-BTA-983705", "name": "Signaling by the B Cell Receptor (BCR)", "reactions": [ "reaction_10091817", "reaction_10056239", "reaction_10075923" ] }, "R-BTA-2142712": { "id": "pathway_10094248", "reactome": "R-BTA-2142712", "name": "Synthesis of 12-eicosatetraenoic acid derivatives", "reactions": [ "reaction_10064534", "reaction_10064565", "reaction_10064554", "reaction_10064567" ] }, "R-BTA-1461973": { "id": "pathway_10094080", "reactome": "R-BTA-1461973", "name": "Defensins", "reactions": [ "reaction_10058486", "reaction_10061657", "reaction_10058492", "reaction_10058456", "reaction_10058388" ] }, "R-BTA-111996": { "id": "pathway_10092788", "reactome": "R-BTA-111996", "name": "Ca-dependent events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-1307965": { "id": "pathway_10094066", "reactome": "R-BTA-1307965", "name": "betaKlotho-mediated ligand binding", "reactions": [ "reaction_10057704", "reaction_10057707" ] }, "R-BTA-391160": { "id": "pathway_10093620", "reactome": "R-BTA-391160", "name": "Signal regulatory protein family interactions", "reactions": [ "reaction_10047292" ] }, "R-BTA-428643": { "id": "pathway_10093496", "reactome": "R-BTA-428643", "name": "Organic anion transporters", "reactions": [ "reaction_10049170", "reaction_10049173", "reaction_10045050", "reaction_10048958", "reaction_10048821", "reaction_10060218", "reaction_10085896", "reaction_10049083" ] }, "R-BTA-5654687": { "id": "pathway_10094516", "reactome": "R-BTA-5654687", "name": "Downstream signaling of activated FGFR1", "reactions": [ "reaction_10073326", "reaction_10073083", "reaction_10073090", "reaction_10073108", "reaction_10072935", "reaction_10073106", "reaction_10073113", "reaction_10072920", "reaction_10073225", "reaction_10073087", "reaction_10073122", "reaction_10073115", "reaction_10073228", "reaction_10087373", "reaction_10073102", "reaction_10072957", "reaction_10073097", "reaction_10073119", "reaction_10072937" ] }, "R-BTA-182971": { "id": "pathway_10093144", "reactome": "R-BTA-182971", "name": "EGFR downregulation", "reactions": [ "reaction_10040462", "reaction_10040460", "reaction_10040421", "reaction_10040393", "reaction_10040458", "reaction_10040432", "reaction_10040453", "reaction_10040369", "reaction_10040447", "reaction_10040451", "reaction_10040386" ] }, "R-BTA-201722": { "id": "pathway_10094352", "reactome": "R-BTA-201722", "name": "Formation of the beta-catenin:TCF transactivating complex", "reactions": [ "reaction_10067879" ] }, "R-BTA-5099900": { "id": "pathway_10094412", "reactome": "R-BTA-5099900", "name": "WNT5A-dependent internalization of FZD4", "reactions": [ "reaction_10069876", "reaction_10069882" ] }, "R-BTA-163125": { "id": "pathway_10092958", "reactome": "R-BTA-163125", "name": "Post-translational modification: synthesis of GPI-anchored proteins", "reactions": [ "reaction_10038464", "reaction_10038457" ] }, "R-BTA-77286": { "id": "pathway_10092706", "reactome": "R-BTA-77286", "name": "mitochondrial fatty acid beta-oxidation of saturated fatty acids", "reactions": [ "reaction_10036027", "reaction_10036023", "reaction_10036021", "reaction_10036042", "reaction_10036029", "reaction_10036025", "reaction_10036040", "reaction_10036012", "reaction_10036038" ] }, "R-BTA-71291": { "id": "pathway_10092486", "reactome": "R-BTA-71291", "name": "Metabolism of amino acids and derivatives", "reactions": [ "reaction_10060216", "reaction_10033849", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10076984", "reaction_10033778", "reaction_10090172", "reaction_10076459", "reaction_10052043", "reaction_10034004", "reaction_10043978", "reaction_10090175", "reaction_10051185", "reaction_10033953", "reaction_10078701", "reaction_10052030", "reaction_10045036", "reaction_10054601", "reaction_10043980", "reaction_10060207", "reaction_10085381", "reaction_10060252", "reaction_10033788", "reaction_10086033", "reaction_10078402", "reaction_10090015", "reaction_10090679", "reaction_10090681", "reaction_10064346", "reaction_10044784", "reaction_10033681", "reaction_10054611", "reaction_10078529", "reaction_10044776", "reaction_10043956", "reaction_10033755", "reaction_10043924", "reaction_10076261", "reaction_10060250", "reaction_10077864", "reaction_10043917", "reaction_10044851", "reaction_10077758", "reaction_10060264", "reaction_10033797", "reaction_10089850", "reaction_10042847", "reaction_10033962", "reaction_10060234", "reaction_10086371", "reaction_10033997", "reaction_10045029", "reaction_10076974", "reaction_10043933", "reaction_10033718", "reaction_10047022", "reaction_10060255", "reaction_10090162", "reaction_10041894", "reaction_10033737", "reaction_10043948", "reaction_10044794", "reaction_10044828", "reaction_10033824", "reaction_10033697", "reaction_10033728", "reaction_10077458", "reaction_10044837", "reaction_10033706", "reaction_10078366", "reaction_10090647", "reaction_10054585", "reaction_10076450", "reaction_10033840", "reaction_10052046", "reaction_10065455", "reaction_10087455", "reaction_10052027", "reaction_10033935", "reaction_10033833", "reaction_10044835", "reaction_10077124", "reaction_10078575", "reaction_10076360", "reaction_10057684", "reaction_10054620", "reaction_10043986", "reaction_10044801", "reaction_10044844", "reaction_10033969", "reaction_10090671", "reaction_10083204", "reaction_10057032", "reaction_10060361", "reaction_10057023", "reaction_10073477", "reaction_10033716", "reaction_10033757", "reaction_10060228", "reaction_10033979", "reaction_10033770", "reaction_10052040", "reaction_10052056", "reaction_10090155", "reaction_10089959", "reaction_10076441", "reaction_10033806", "reaction_10033944", "reaction_10033690", "reaction_10076406", "reaction_10078393", "reaction_10042838", "reaction_10047019", "reaction_10060218", "reaction_10051165", "reaction_10033988", "reaction_10077444", "reaction_10051198", "reaction_10077435", "reaction_10076130", "reaction_10090013", "reaction_10060231", "reaction_10077453" ] }, "R-BTA-2672351": { "id": "pathway_10094314", "reactome": "R-BTA-2672351", "name": "Stimuli-sensing channels", "reactions": [ "reaction_10091583", "reaction_10066232", "reaction_10067346", "reaction_10091542", "reaction_10066282", "reaction_10092050", "reaction_10066270", "reaction_10066227", "reaction_10066004", "reaction_10066199", "reaction_10066034", "reaction_10066021", "reaction_10084767", "reaction_10066289", "reaction_10067332", "reaction_10065965", "reaction_10066277", "reaction_10065991", "reaction_10066206" ] }, "R-BTA-5654227": { "id": "pathway_10094510", "reactome": "R-BTA-5654227", "name": "Phospholipase C-mediated cascade; FGFR3", "reactions": [ "reaction_10072946", "reaction_10072944", "reaction_10072913" ] }, "R-BTA-447043": { "id": "pathway_10093506", "reactome": "R-BTA-447043", "name": "Neurofascin interactions", "reactions": [ "reaction_10045224" ] }, "R-BTA-428930": { "id": "pathway_10093632", "reactome": "R-BTA-428930", "name": "Thromboxane signalling through TP receptor", "reactions": [ "reaction_10091701", "reaction_10049014", "reaction_10049035", "reaction_10047380" ] }, "R-BTA-421270": { "id": "pathway_10093688", "reactome": "R-BTA-421270", "name": "Cell-cell junction organization", "reactions": [ "reaction_10048352", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-418346": { "id": "pathway_10092852", "reactome": "R-BTA-418346", "name": "Platelet homeostasis", "reactions": [ "reaction_10049283", "reaction_10044018", "reaction_10048504", "reaction_10037607", "reaction_10047900", "reaction_10049290", "reaction_10048182", "reaction_10047893", "reaction_10047907", "reaction_10047930", "reaction_10049364", "reaction_10048635", "reaction_10044043", "reaction_10085323" ] }, "R-BTA-196741": { "id": "pathway_10092516", "reactome": "R-BTA-196741", "name": "Cobalamin (Cbl, vitamin B12) transport and metabolism", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10033889", "reaction_10066430", "reaction_10066585", "reaction_10066571", "reaction_10066526", "reaction_10066473", "reaction_10066461", "reaction_10066882", "reaction_10066444", "reaction_10066574", "reaction_10076254", "reaction_10066576", "reaction_10066458", "reaction_10066502", "reaction_10066587", "reaction_10066528", "reaction_10066569" ] }, "R-BTA-5620920": { "id": "pathway_10094490", "reactome": "R-BTA-5620920", "name": "Cargo trafficking to the periciliary membrane", "reactions": [ "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072489", "reaction_10072453", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-1296071": { "id": "pathway_10094028", "reactome": "R-BTA-1296071", "name": "Potassium Channels", "reactions": [ "reaction_10057418", "reaction_10057665", "reaction_10057399", "reaction_10057569", "reaction_10057616", "reaction_10057350", "reaction_10057682", "reaction_10057365", "reaction_10057656", "reaction_10057639", "reaction_10057588", "reaction_10057390", "reaction_10057607" ] }, "R-BTA-1236974": { "id": "pathway_10093998", "reactome": "R-BTA-1236974", "name": "ER-Phagosome pathway", "reactions": [ "reaction_10056982", "reaction_10084867", "reaction_10087823", "reaction_10084865" ] }, "R-BTA-195253": { "id": "pathway_10093270", "reactome": "R-BTA-195253", "name": "Degradation of beta-catenin by the destruction complex", "reactions": [ "reaction_10041647", "reaction_10063849", "reaction_10071356", "reaction_10041604", "reaction_10041629", "reaction_10041606", "reaction_10070931", "reaction_10041637", "reaction_10063843", "reaction_10069651", "reaction_10087597", "reaction_10041583", "reaction_10041640" ] }, "R-BTA-112307": { "id": "pathway_10093518", "reactome": "R-BTA-112307", "name": "Transmission across Electrical Synapses ", "reactions": [ "reaction_10045444", "reaction_10045455", "reaction_10045466" ] }, "R-BTA-9027307": { "id": "pathway_10094942", "reactome": "R-BTA-9027307", "name": "Biosynthesis of maresin-like SPMs", "reactions": [ "reaction_10090498" ] }, "R-BTA-2980766": { "id": "pathway_10094320", "reactome": "R-BTA-2980766", "name": "Nuclear Envelope Breakdown", "reactions": [ "reaction_10070705", "reaction_10069491", "reaction_10066345", "reaction_10066324" ] }, "R-BTA-8964043": { "id": "pathway_10094710", "reactome": "R-BTA-8964043", "name": "Plasma lipoprotein clearance", "reactions": [ "reaction_10086004", "reaction_10086002", "reaction_10084300", "reaction_10086026", "reaction_10086557", "reaction_10083113", "reaction_10085994" ] }, "R-BTA-211976": { "id": "pathway_10093240", "reactome": "R-BTA-211976", "name": "Endogenous sterols", "reactions": [ "reaction_10041193", "reaction_10041412", "reaction_10041386", "reaction_10041277", "reaction_10041397", "reaction_10041217", "reaction_10041206", "reaction_10044232", "reaction_10041415", "reaction_10077751", "reaction_10041177", "reaction_10041195", "reaction_10041500", "reaction_10041393" ] }, "R-BTA-5218921": { "id": "pathway_10094430", "reactome": "R-BTA-5218921", "name": "VEGFR2 mediated cell proliferation", "reactions": [ "reaction_10070615", "reaction_10070628", "reaction_10070657" ] }, "R-BTA-69052": { "id": "pathway_10092418", "reactome": "R-BTA-69052", "name": "Switching of origins to a post-replicative state", "reactions": [ "reaction_10033473" ] }, "R-BTA-75892": { "id": "pathway_10093422", "reactome": "R-BTA-75892", "name": "Platelet Adhesion to exposed collagen", "reactions": [ "reaction_10044020", "reaction_10049300" ] }, "R-BTA-212718": { "id": "pathway_10093446", "reactome": "R-BTA-212718", "name": "EGFR interacts with phospholipase C-gamma", "reactions": [ "reaction_10044465", "reaction_10044470", "reaction_10044472" ] }, "R-BTA-2029480": { "id": "pathway_10093300", "reactome": "R-BTA-2029480", "name": "Fcgamma receptor (FCGR) dependent phagocytosis", "reactions": [ "reaction_10061174", "reaction_10063353", "reaction_10063374", "reaction_10063368", "reaction_10041863" ] }, "R-BTA-390650": { "id": "pathway_10093616", "reactome": "R-BTA-390650", "name": "Histamine receptors", "reactions": [ "reaction_10091825", "reaction_10047234", "reaction_10047226" ] }, "R-BTA-1640170": { "id": "pathway_10092414", "reactome": "R-BTA-1640170", "name": "Cell Cycle", "reactions": [ "reaction_10051463", "reaction_10040542", "reaction_10084051", "reaction_10035745", "reaction_10065938", "reaction_10040576", "reaction_10040503", "reaction_10057808", "reaction_10039612", "reaction_10070705", "reaction_10091661", "reaction_10076341", "reaction_10065177", "reaction_10065201", "reaction_10091145", "reaction_10083565", "reaction_10040183", "reaction_10084102", "reaction_10065708", "reaction_10084047", "reaction_10087503", "reaction_10057812", "reaction_10087487", "reaction_10065095", "reaction_10038033", "reaction_10091685", "reaction_10038949", "reaction_10056602", "reaction_10064904", "reaction_10066487", "reaction_10069491", "reaction_10039614", "reaction_10056616", "reaction_10051465", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10057804", "reaction_10066489", "reaction_10040355", "reaction_10084096", "reaction_10091132", "reaction_10033512", "reaction_10065572", "reaction_10084090", "reaction_10091663", "reaction_10065563", "reaction_10040521", "reaction_10038947", "reaction_10051451", "reaction_10057821", "reaction_10064733", "reaction_10035747", "reaction_10078408", "reaction_10087385", "reaction_10084206", "reaction_10040059", "reaction_10065726", "reaction_10091634", "reaction_10033504", "reaction_10091658", "reaction_10033473", "reaction_10039801", "reaction_10033535", "reaction_10066345", "reaction_10084043", "reaction_10091656", "reaction_10033466", "reaction_10057816", "reaction_10051461", "reaction_10074695", "reaction_10091141", "reaction_10084028", "reaction_10065794", "reaction_10081470", "reaction_10087394", "reaction_10038035", "reaction_10083558", "reaction_10074692", "reaction_10038540", "reaction_10038534", "reaction_10066324" ] }, "R-BTA-442742": { "id": "pathway_10094950", "reactome": "R-BTA-442742", "name": "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling", "reactions": [ "reaction_10090547" ] }, "R-BTA-1247673": { "id": "pathway_10094010", "reactome": "R-BTA-1247673", "name": "Erythrocytes take up oxygen and release carbon dioxide", "reactions": [ "reaction_10057070", "reaction_10058792" ] }, "R-BTA-426117": { "id": "pathway_10093710", "reactome": "R-BTA-426117", "name": "Cation-coupled Chloride cotransporters", "reactions": [ "reaction_10048601", "reaction_10048594", "reaction_10048618" ] }, "R-BTA-3296197": { "id": "pathway_10093772", "reactome": "R-BTA-3296197", "name": "Hydroxycarboxylic acid-binding receptors", "reactions": [ "reaction_10067364", "reaction_10067362", "reaction_10049659" ] }, "R-BTA-1655829": { "id": "pathway_10094140", "reactome": "R-BTA-1655829", "name": "Regulation of cholesterol biosynthesis by SREBP (SREBF)", "reactions": [ "reaction_10063562", "reaction_10063560", "reaction_10063564", "reaction_10060346" ] }, "R-BTA-9033500": { "id": "pathway_10094956", "reactome": "R-BTA-9033500", "name": "TYSND1 cleaves peroxisomal proteins", "reactions": [ "reaction_10090604" ] }, "R-BTA-6785807": { "id": "pathway_10094642", "reactome": "R-BTA-6785807", "name": "Interleukin-4 and Interleukin-13 signaling", "reactions": [ "reaction_10077633", "reaction_10077870", "reaction_10077945", "reaction_10091731", "reaction_10077723", "reaction_10077764", "reaction_10077874" ] }, "R-BTA-450282": { "id": "pathway_10093058", "reactome": "R-BTA-450282", "name": "MAPK targets/ Nuclear events mediated by MAP kinases", "reactions": [ "reaction_10050208", "reaction_10041950", "reaction_10039508", "reaction_10043488", "reaction_10042826" ] }, "R-BTA-442660": { "id": "pathway_10093478", "reactome": "R-BTA-442660", "name": "Na+/Cl- dependent neurotransmitter transporters", "reactions": [ "reaction_10045480", "reaction_10049599", "reaction_10044934", "reaction_10045419", "reaction_10044941", "reaction_10049583", "reaction_10045487", "reaction_10049613", "reaction_10044948", "reaction_10049592" ] }, "R-BTA-9006335": { "id": "pathway_10094886", "reactome": "R-BTA-9006335", "name": "Signaling by Erythropoietin", "reactions": [ "reaction_10090501", "reaction_10090428", "reaction_10089841" ] }, "R-BTA-8963684": { "id": "pathway_10092540", "reactome": "R-BTA-8963684", "name": "Tyrosine catabolism", "reactions": [ "reaction_10033962", "reaction_10033953", "reaction_10033944" ] }, "R-BTA-70268": { "id": "pathway_10092478", "reactome": "R-BTA-70268", "name": "Pyruvate metabolism", "reactions": [ "reaction_10089721", "reaction_10034240", "reaction_10076468", "reaction_10089728", "reaction_10033671" ] }, "R-BTA-418597": { "id": "pathway_10093638", "reactome": "R-BTA-418597", "name": "G alpha (z) signalling events", "reactions": [ "reaction_10089217", "reaction_10089207", "reaction_10047468", "reaction_10089167", "reaction_10051656" ] }, "R-BTA-111464": { "id": "pathway_10092834", "reactome": "R-BTA-111464", "name": "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ", "reactions": [ "reaction_10037293" ] }, "R-BTA-72662": { "id": "pathway_10092574", "reactome": "R-BTA-72662", "name": "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S", "reactions": [ "reaction_10034365" ] }, "R-BTA-9027604": { "id": "pathway_10094946", "reactome": "R-BTA-9027604", "name": "Biosynthesis of electrophilic \u03c9-3 PUFA oxo-derivatives", "reactions": [ "reaction_10090504", "reaction_10090506", "reaction_10090508", "reaction_10090510" ] }, "R-BTA-5693607": { "id": "pathway_10094588", "reactome": "R-BTA-5693607", "name": "Processing of DNA double-strand break ends", "reactions": [ "reaction_10074798", "reaction_10076339", "reaction_10075037" ] }, "R-BTA-1483257": { "id": "pathway_10092670", "reactome": "R-BTA-1483257", "name": "Phospholipid metabolism", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10082931", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10060614", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10060569", "reaction_10035786", "reaction_10082934", "reaction_10058913", "reaction_10060597", "reaction_10085808", "reaction_10060600", "reaction_10058998", "reaction_10085798", "reaction_10060590", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10060579", "reaction_10084526", "reaction_10071344", "reaction_10060448", "reaction_10060429", "reaction_10083369", "reaction_10083211", "reaction_10059035", "reaction_10082155", "reaction_10058996", "reaction_10058970", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10060572", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10060518", "reaction_10058834", "reaction_10085340", "reaction_10082152", "reaction_10058874", "reaction_10085784", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10060588", "reaction_10060476", "reaction_10085843", "reaction_10060498", "reaction_10059073", "reaction_10060535", "reaction_10059114", "reaction_10060537", "reaction_10058892", "reaction_10082147", "reaction_10060516", "reaction_10059014", "reaction_10082136", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10060468", "reaction_10085780", "reaction_10085024", "reaction_10058899", "reaction_10060501", "reaction_10060553", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10083092", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10083800", "reaction_10060556", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10085775", "reaction_10086064", "reaction_10058980", "reaction_10060550", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058841", "reaction_10059026", "reaction_10060483", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10060595", "reaction_10059101", "reaction_10060574", "reaction_10058948", "reaction_10058985", "reaction_10060558", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10060461", "reaction_10076824" ] }, "R-BTA-156584": { "id": "pathway_10092914", "reactome": "R-BTA-156584", "name": "Cytosolic sulfonation of small molecules", "reactions": [ "reaction_10040147", "reaction_10039887", "reaction_10038318", "reaction_10038231", "reaction_10040136", "reaction_10040129", "reaction_10039890", "reaction_10048727", "reaction_10040131", "reaction_10040122", "reaction_10040157", "reaction_10040112", "reaction_10040115", "reaction_10076799", "reaction_10040120", "reaction_10038340", "reaction_10038320", "reaction_10040107", "reaction_10040152", "reaction_10040098", "reaction_10051570", "reaction_10088617", "reaction_10040117", "reaction_10088580" ] }, "R-BTA-450408": { "id": "pathway_10093808", "reactome": "R-BTA-450408", "name": "AUF1 (hnRNP D0) binds and destabilizes mRNA", "reactions": [ "reaction_10050342" ] }, "R-BTA-9648002": { "id": "pathway_10095012", "reactome": "R-BTA-9648002", "name": "RAS processing", "reactions": [ "reaction_10091490", "reaction_10091458", "reaction_10091506", "reaction_10091527", "reaction_10091515", "reaction_10091479" ] }, "R-BTA-5654688": { "id": "pathway_10094536", "reactome": "R-BTA-5654688", "name": "SHC-mediated cascade:FGFR1", "reactions": [ "reaction_10073119", "reaction_10073102", "reaction_10073122", "reaction_10073087" ] }, "R-BTA-211916": { "id": "pathway_10093416", "reactome": "R-BTA-211916", "name": "Vitamins", "reactions": [ "reaction_10044225", "reaction_10044211", "reaction_10044293", "reaction_10043971", "reaction_10043964" ] }, "R-BTA-6811555": { "id": "pathway_10094694", "reactome": "R-BTA-6811555", "name": "PI5P Regulates TP53 Acetylation", "reactions": [ "reaction_10082931", "reaction_10083092", "reaction_10086155", "reaction_10083077", "reaction_10083072", "reaction_10082923", "reaction_10082934" ] }, "R-BTA-5173214": { "id": "pathway_10094416", "reactome": "R-BTA-5173214", "name": "O-glycosylation of TSR domain-containing proteins", "reactions": [ "reaction_10070145" ] }, "R-BTA-2142789": { "id": "pathway_10094254", "reactome": "R-BTA-2142789", "name": "Ubiquinol biosynthesis", "reactions": [ "reaction_10064591" ] }, "R-BTA-1614603": { "id": "pathway_10094130", "reactome": "R-BTA-1614603", "name": "Cysteine formation from homocysteine", "reactions": [ "reaction_10060231", "reaction_10060207" ] }, "R-BTA-389356": { "id": "pathway_10093568", "reactome": "R-BTA-389356", "name": "CD28 co-stimulation", "reactions": [ "reaction_10046907", "reaction_10046943", "reaction_10047530", "reaction_10065227", "reaction_10046932", "reaction_10046951", "reaction_10046822", "reaction_10046811", "reaction_10046787" ] }, "R-BTA-9609507": { "id": "pathway_10094876", "reactome": "R-BTA-9609507", "name": "Protein localization", "reactions": [ "reaction_10090604", "reaction_10089391", "reaction_10090770", "reaction_10090593" ] }, "R-BTA-9675108": { "id": "pathway_10093386", "reactome": "R-BTA-9675108", "name": "Nervous system development", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10091009", "reaction_10084393", "reaction_10084185", "reaction_10091007", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-163210": { "id": "pathway_10092994", "reactome": "R-BTA-163210", "name": "Formation of ATP by chemiosmotic coupling", "reactions": [ "reaction_10039049", "reaction_10039044", "reaction_10039047" ] }, "R-BTA-112314": { "id": "pathway_10092800", "reactome": "R-BTA-112314", "name": "Neurotransmitter receptors and postsynaptic signal transmission", "reactions": [ "reaction_10051085", "reaction_10039653", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10050517", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10054318", "reaction_10054372", "reaction_10036981", "reaction_10051498", "reaction_10090547", "reaction_10051525", "reaction_10049478", "reaction_10051523", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10039664" ] }, "R-BTA-77108": { "id": "pathway_10092612", "reactome": "R-BTA-77108", "name": "Utilization of Ketone Bodies", "reactions": [ "reaction_10035374", "reaction_10035415", "reaction_10035417" ] }, "R-BTA-69278": { "id": "pathway_10092412", "reactome": "R-BTA-69278", "name": "Cell Cycle, Mitotic", "reactions": [ "reaction_10057804", "reaction_10084102", "reaction_10039801", "reaction_10066489", "reaction_10065708", "reaction_10084047", "reaction_10040542", "reaction_10066345", "reaction_10040355", "reaction_10084096", "reaction_10087503", "reaction_10091132", "reaction_10084043", "reaction_10084051", "reaction_10035745", "reaction_10033512", "reaction_10065938", "reaction_10057812", "reaction_10065572", "reaction_10091656", "reaction_10087487", "reaction_10084090", "reaction_10033466", "reaction_10065095", "reaction_10057816", "reaction_10040576", "reaction_10040503", "reaction_10038033", "reaction_10065563", "reaction_10091141", "reaction_10084028", "reaction_10057808", "reaction_10039612", "reaction_10056602", "reaction_10070705", "reaction_10065794", "reaction_10033473", "reaction_10040521", "reaction_10087394", "reaction_10091661", "reaction_10057821", "reaction_10038035", "reaction_10064733", "reaction_10083558", "reaction_10087385", "reaction_10084206", "reaction_10065177", "reaction_10064904", "reaction_10066487", "reaction_10065201", "reaction_10069491", "reaction_10035747", "reaction_10065726", "reaction_10039614", "reaction_10091145", "reaction_10056616", "reaction_10091634", "reaction_10033504", "reaction_10083565", "reaction_10040183", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10091658", "reaction_10066324" ] }, "R-BTA-5654221": { "id": "pathway_10094506", "reactome": "R-BTA-5654221", "name": "Phospholipase C-mediated cascade; FGFR2", "reactions": [ "reaction_10072931", "reaction_10072909", "reaction_10072929" ] }, "R-BTA-181438": { "id": "pathway_10093042", "reactome": "R-BTA-181438", "name": "Toll Like Receptor 2 (TLR2) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-6814122": { "id": "pathway_10094716", "reactome": "R-BTA-6814122", "name": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-141430": { "id": "pathway_10092902", "reactome": "R-BTA-141430", "name": "Inactivation of APC/C via direct inhibition of the APC/C complex", "reactions": [ "reaction_10038035" ] }, "R-BTA-112040": { "id": "pathway_10092772", "reactome": "R-BTA-112040", "name": "G-protein mediated events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10039653", "reaction_10036981", "reaction_10039671", "reaction_10037045", "reaction_10039674", "reaction_10049478", "reaction_10039676", "reaction_10036959", "reaction_10039651", "reaction_10037024", "reaction_10039667", "reaction_10039658", "reaction_10039664" ] }, "R-BTA-2514856": { "id": "pathway_10092626", "reactome": "R-BTA-2514856", "name": "The phototransduction cascade", "reactions": [ "reaction_10035596", "reaction_10065944", "reaction_10065808", "reaction_10035406", "reaction_10035619", "reaction_10077744", "reaction_10065940" ] }, "R-BTA-193648": { "id": "pathway_10093256", "reactome": "R-BTA-193648", "name": "NRAGE signals death through JNK", "reactions": [ "reaction_10043753", "reaction_10041333" ] }, "R-BTA-844456": { "id": "pathway_10093864", "reactome": "R-BTA-844456", "name": "The NLRP3 inflammasome", "reactions": [ "reaction_10051836" ] }, "R-BTA-6806664": { "id": "pathway_10092948", "reactome": "R-BTA-6806664", "name": "Metabolism of vitamin K", "reactions": [ "reaction_10081935", "reaction_10081928", "reaction_10090493", "reaction_10038427" ] }, "R-BTA-6794361": { "id": "pathway_10094660", "reactome": "R-BTA-6794361", "name": "Neurexins and neuroligins", "reactions": [ "reaction_10078522", "reaction_10078488", "reaction_10078446", "reaction_10078518", "reaction_10078600", "reaction_10078464", "reaction_10078466" ] }, "R-BTA-204998": { "id": "pathway_10093258", "reactome": "R-BTA-204998", "name": "Cell death signalling via NRAGE, NRIF and NADE", "reactions": [ "reaction_10043744", "reaction_10043753", "reaction_10043778", "reaction_10043739", "reaction_10041333" ] }, "R-BTA-381676": { "id": "pathway_10093552", "reactome": "R-BTA-381676", "name": "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion", "reactions": [ "reaction_10046630", "reaction_10046642", "reaction_10046623", "reaction_10046648" ] }, "R-BTA-75157": { "id": "pathway_10092530", "reactome": "R-BTA-75157", "name": "FasL/ CD95L signaling", "reactions": [ "reaction_10036148", "reaction_10036146", "reaction_10033926", "reaction_10035726" ] }, "R-BTA-727802": { "id": "pathway_10093118", "reactome": "R-BTA-727802", "name": "Transport of nucleotide sugars", "reactions": [ "reaction_10051577", "reaction_10039874", "reaction_10051570", "reaction_10051580", "reaction_10051554", "reaction_10051587", "reaction_10051589" ] }, "R-BTA-379726": { "id": "pathway_10093796", "reactome": "R-BTA-379726", "name": "Mitochondrial tRNA aminoacylation", "reactions": [ "reaction_10050169" ] }, "R-BTA-199418": { "id": "pathway_10094148", "reactome": "R-BTA-199418", "name": "Negative regulation of the PI3K/AKT network", "reactions": [ "reaction_10060556", "reaction_10060448" ] }, "R-BTA-6811442": { "id": "pathway_10094704", "reactome": "R-BTA-6811442", "name": "Intra-Golgi and retrograde Golgi-to-ER traffic", "reactions": [ "reaction_10083458", "reaction_10083425", "reaction_10083340", "reaction_10083342", "reaction_10083006", "reaction_10082999", "reaction_10083767", "reaction_10083712", "reaction_10083451", "reaction_10083143", "reaction_10083004", "reaction_10083179", "reaction_10083187", "reaction_10083149", "reaction_10083056" ] }, "R-BTA-3769402": { "id": "pathway_10094350", "reactome": "R-BTA-3769402", "name": "Deactivation of the beta-catenin transactivating complex", "reactions": [ "reaction_10067694", "reaction_10067696", "reaction_10067698" ] }, "R-BTA-8957322": { "id": "pathway_10092930", "reactome": "R-BTA-8957322", "name": "Metabolism of steroids", "reactions": [ "reaction_10041308", "reaction_10041363", "reaction_10041297", "reaction_10041104", "reaction_10050650", "reaction_10077113", "reaction_10041359", "reaction_10081990", "reaction_10041323", "reaction_10041284", "reaction_10041186", "reaction_10084679", "reaction_10041321", "reaction_10041437", "reaction_10041671", "reaction_10041684", "reaction_10063560", "reaction_10041277", "reaction_10041319", "reaction_10041179", "reaction_10041477", "reaction_10076281", "reaction_10041500", "reaction_10041337", "reaction_10041377", "reaction_10044739", "reaction_10041721", "reaction_10041172", "reaction_10040904", "reaction_10041486", "reaction_10043885", "reaction_10041177", "reaction_10040913", "reaction_10043971", "reaction_10041386", "reaction_10041357", "reaction_10040881", "reaction_10041226", "reaction_10041347", "reaction_10041341", "reaction_10041415", "reaction_10081988", "reaction_10041310", "reaction_10041325", "reaction_10081986", "reaction_10041111", "reaction_10041170", "reaction_10041290", "reaction_10040895", "reaction_10041327", "reaction_10060346", "reaction_10041193", "reaction_10041206", "reaction_10083496", "reaction_10041664", "reaction_10041373", "reaction_10041293", "reaction_10043903", "reaction_10043910", "reaction_10041716", "reaction_10088928", "reaction_10085316", "reaction_10041412", "reaction_10063562", "reaction_10063564", "reaction_10041692", "reaction_10041484", "reaction_10041349", "reaction_10041379", "reaction_10092062", "reaction_10038347", "reaction_10041397", "reaction_10041493", "reaction_10041210", "reaction_10044741", "reaction_10041393", "reaction_10041345", "reaction_10041204", "reaction_10041367", "reaction_10040924", "reaction_10041339", "reaction_10041097", "reaction_10041301", "reaction_10041502", "reaction_10041299", "reaction_10041195", "reaction_10088926", "reaction_10041369", "reaction_10085806", "reaction_10041197", "reaction_10041343", "reaction_10041208", "reaction_10085291", "reaction_10041355", "reaction_10041365", "reaction_10040933", "reaction_10041424", "reaction_10041728", "reaction_10040892", "reaction_10092065", "reaction_10041351", "reaction_10041719", "reaction_10041371", "reaction_10041375", "reaction_10041269", "reaction_10041295", "reaction_10057880", "reaction_10041395", "reaction_10088019", "reaction_10041335", "reaction_10043964", "reaction_10041353", "reaction_10043984", "reaction_10041317", "reaction_10041361", "reaction_10041217", "reaction_10040922", "reaction_10051676" ] }, "R-BTA-379724": { "id": "pathway_10092568", "reactome": "R-BTA-379724", "name": "tRNA Aminoacylation", "reactions": [ "reaction_10050169", "reaction_10034224" ] }, "R-BTA-1971475": { "id": "pathway_10094180", "reactome": "R-BTA-1971475", "name": "A tetrasaccharide linker sequence is required for GAG synthesis", "reactions": [ "reaction_10061395", "reaction_10061402", "reaction_10061350", "reaction_10061251", "reaction_10091286" ] }, "R-BTA-9639288": { "id": "pathway_10095008", "reactome": "R-BTA-9639288", "name": "Amino acids regulate mTORC1", "reactions": [ "reaction_10091354", "reaction_10091356", "reaction_10091336", "reaction_10091365", "reaction_10091351", "reaction_10091401", "reaction_10091404" ] }, "R-BTA-191650": { "id": "pathway_10093228", "reactome": "R-BTA-191650", "name": "Regulation of gap junction activity", "reactions": [ "reaction_10040967", "reaction_10040955", "reaction_10040961" ] }, "R-BTA-1834941": { "id": "pathway_10094212", "reactome": "R-BTA-1834941", "name": "STING mediated induction of host immune responses", "reactions": [ "reaction_10065388", "reaction_10063376", "reaction_10065413", "reaction_10065407", "reaction_10090019", "reaction_10067233", "reaction_10067223", "reaction_10067216", "reaction_10066880", "reaction_10067231", "reaction_10067229", "reaction_10066532", "reaction_10067225", "reaction_10065402" ] }, "R-BTA-163200": { "id": "pathway_10092970", "reactome": "R-BTA-163200", "name": "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.", "reactions": [ "reaction_10080521", "reaction_10039044", "reaction_10080519", "reaction_10080517", "reaction_10039049", "reaction_10038895", "reaction_10039047", "reaction_10039604", "reaction_10039254", "reaction_10080515", "reaction_10039242", "reaction_10038647", "reaction_10039240" ] }, "R-BTA-2142753": { "id": "pathway_10092870", "reactome": "R-BTA-2142753", "name": "Arachidonic acid metabolism", "reactions": [ "reaction_10064516", "reaction_10065225", "reaction_10064546", "reaction_10064521", "reaction_10065216", "reaction_10037751", "reaction_10065210", "reaction_10064565", "reaction_10064554", "reaction_10065223", "reaction_10064465", "reaction_10064581", "reaction_10044599", "reaction_10086336", "reaction_10064503", "reaction_10064474", "reaction_10037748", "reaction_10064534", "reaction_10077001", "reaction_10065213", "reaction_10064531", "reaction_10064567", "reaction_10064578", "reaction_10064482", "reaction_10064506", "reaction_10064526", "reaction_10064452", "reaction_10044657", "reaction_10064511", "reaction_10044151", "reaction_10076382", "reaction_10064442", "reaction_10064479", "reaction_10064445" ] }, "R-BTA-2465910": { "id": "pathway_10094256", "reactome": "R-BTA-2465910", "name": "MASTL Facilitates Mitotic Progression", "reactions": [ "reaction_10064733", "reaction_10065572" ] }, "R-BTA-449836": { "id": "pathway_10093788", "reactome": "R-BTA-449836", "name": "Other interleukin signaling", "reactions": [ "reaction_10089689", "reaction_10089691", "reaction_10090027", "reaction_10090031", "reaction_10049983", "reaction_10077843" ] }, "R-BTA-77352": { "id": "pathway_10092710", "reactome": "R-BTA-77352", "name": "Beta oxidation of butanoyl-CoA to acetyl-CoA", "reactions": [ "reaction_10036025" ] }, "R-BTA-4420097": { "id": "pathway_10093156", "reactome": "R-BTA-4420097", "name": "VEGFA-VEGFR2 Pathway", "reactions": [ "reaction_10070615", "reaction_10070589", "reaction_10070628", "reaction_10070657", "reaction_10070676", "reaction_10070596", "reaction_10071506", "reaction_10070624", "reaction_10065227", "reaction_10040570", "reaction_10071504", "reaction_10069535", "reaction_10071508", "reaction_10070651", "reaction_10070645", "reaction_10070594" ] }, "R-BTA-264876": { "id": "pathway_10093764", "reactome": "R-BTA-264876", "name": "Insulin processing", "reactions": [ "reaction_10049385", "reaction_10049392" ] }, "R-BTA-5620916": { "id": "pathway_10094488", "reactome": "R-BTA-5620916", "name": "VxPx cargo-targeting to cilium", "reactions": [ "reaction_10072326", "reaction_10072426", "reaction_10072401" ] }, "R-BTA-391251": { "id": "pathway_10094720", "reactome": "R-BTA-391251", "name": "Protein folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-5696399": { "id": "pathway_10092744", "reactome": "R-BTA-5696399", "name": "Global Genome Nucleotide Excision Repair (GG-NER)", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10077016", "reaction_10076071", "reaction_10076009", "reaction_10036661" ] }, "R-BTA-5654689": { "id": "pathway_10094538", "reactome": "R-BTA-5654689", "name": "PI-3K cascade:FGFR1", "reactions": [ "reaction_10073115", "reaction_10073228", "reaction_10073225" ] }, "R-BTA-76002": { "id": "pathway_10092840", "reactome": "R-BTA-76002", "name": "Platelet activation, signaling and aggregation", "reactions": [ "reaction_10050630", "reaction_10092299", "reaction_10048580", "reaction_10048543", "reaction_10050870", "reaction_10051002", "reaction_10047475", "reaction_10049014", "reaction_10053213", "reaction_10050948", "reaction_10037580", "reaction_10048587", "reaction_10049279", "reaction_10049035", "reaction_10049426", "reaction_10037517", "reaction_10050994", "reaction_10049395", "reaction_10047870", "reaction_10065227", "reaction_10037557", "reaction_10047880", "reaction_10076743", "reaction_10047380", "reaction_10045016", "reaction_10037353", "reaction_10049039", "reaction_10047212", "reaction_10051062", "reaction_10049071", "reaction_10047985", "reaction_10047886", "reaction_10091701", "reaction_10049506", "reaction_10037433", "reaction_10048632", "reaction_10037588", "reaction_10048660", "reaction_10047857", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-69190": { "id": "pathway_10092428", "reactome": "R-BTA-69190", "name": "DNA strand elongation", "reactions": [ "reaction_10033504", "reaction_10040183" ] }, "R-BTA-109703": { "id": "pathway_10092954", "reactome": "R-BTA-109703", "name": "PKB-mediated events", "reactions": [ "reaction_10038450" ] }, "R-BTA-388841": { "id": "pathway_10093570", "reactome": "R-BTA-388841", "name": "Costimulation by the CD28 family", "reactions": [ "reaction_10046907", "reaction_10046943", "reaction_10046834", "reaction_10046909", "reaction_10046903", "reaction_10047530", "reaction_10046959", "reaction_10065227", "reaction_10046932", "reaction_10046807", "reaction_10091743", "reaction_10046951", "reaction_10046822", "reaction_10046811", "reaction_10046787", "reaction_10046888" ] }, "R-BTA-674695": { "id": "pathway_10092810", "reactome": "R-BTA-674695", "name": "RNA Polymerase II Pre-transcription Events", "reactions": [ "reaction_10037189", "reaction_10037187", "reaction_10037185", "reaction_10037207", "reaction_10037201" ] }, "R-BTA-9034015": { "id": "pathway_10094964", "reactome": "R-BTA-9034015", "name": "Signaling by NTRK3 (TRKC)", "reactions": [ "reaction_10090666", "reaction_10090675", "reaction_10090727", "reaction_10090722" ] }, "R-BTA-3371453": { "id": "pathway_10094360", "reactome": "R-BTA-3371453", "name": "Regulation of HSF1-mediated heat shock response", "reactions": [ "reaction_10071208", "reaction_10071127", "reaction_10068008", "reaction_10067993", "reaction_10071313", "reaction_10071241" ] }, "R-BTA-174362": { "id": "pathway_10093120", "reactome": "R-BTA-174362", "name": "Transport and synthesis of PAPS", "reactions": [ "reaction_10039890", "reaction_10039887", "reaction_10048727", "reaction_10051570" ] }, "R-BTA-429593": { "id": "pathway_10093734", "reactome": "R-BTA-429593", "name": "Inositol transporters", "reactions": [ "reaction_10049060", "reaction_10049078" ] }, "R-BTA-8849469": { "id": "pathway_10094738", "reactome": "R-BTA-8849469", "name": "PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1", "reactions": [ "reaction_10083646", "reaction_10083638", "reaction_10083632", "reaction_10083652" ] }, "R-BTA-77285": { "id": "pathway_10092708", "reactome": "R-BTA-77285", "name": "Beta oxidation of myristoyl-CoA to lauroyl-CoA", "reactions": [ "reaction_10036023" ] }, "R-BTA-6785631": { "id": "pathway_10094640", "reactome": "R-BTA-6785631", "name": "ERBB2 Regulates Cell Motility", "reactions": [ "reaction_10077605", "reaction_10077601" ] }, "R-BTA-1428517": { "id": "pathway_10092482", "reactome": "R-BTA-1428517", "name": "The citric acid (TCA) cycle and respiratory electron transport", "reactions": [ "reaction_10080521", "reaction_10039044", "reaction_10051980", "reaction_10038895", "reaction_10051973", "reaction_10089795", "reaction_10089782", "reaction_10080517", "reaction_10089721", "reaction_10039047", "reaction_10089808", "reaction_10080519", "reaction_10039254", "reaction_10039049", "reaction_10039604", "reaction_10080515", "reaction_10050437", "reaction_10076468", "reaction_10039240", "reaction_10034240", "reaction_10050446", "reaction_10089728", "reaction_10039242", "reaction_10038647", "reaction_10033868", "reaction_10033671" ] }, "R-BTA-1482801": { "id": "pathway_10094102", "reactome": "R-BTA-1482801", "name": "Acyl chain remodelling of PS", "reactions": [ "reaction_10058943", "reaction_10058880", "reaction_10059014", "reaction_10058945", "reaction_10059849", "reaction_10085310", "reaction_10058916" ] }, "R-BTA-1912420": { "id": "pathway_10094182", "reactome": "R-BTA-1912420", "name": "Pre-NOTCH Processing in Golgi", "reactions": [ "reaction_10061449" ] }, "R-BTA-189200": { "id": "pathway_10093732", "reactome": "R-BTA-189200", "name": "Cellular hexose transport", "reactions": [ "reaction_10089038", "reaction_10089029", "reaction_10085907", "reaction_10049053", "reaction_10089024", "reaction_10049046" ] }, "R-BTA-159854": { "id": "pathway_10092942", "reactome": "R-BTA-159854", "name": "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins", "reactions": [ "reaction_10038438", "reaction_10038408", "reaction_10038416" ] }, "R-BTA-111457": { "id": "pathway_10092820", "reactome": "R-BTA-111457", "name": "Release of apoptotic factors from the mitochondria", "reactions": [ "reaction_10081897", "reaction_10037253", "reaction_10037264", "reaction_10091186" ] }, "R-BTA-376176": { "id": "pathway_10093382", "reactome": "R-BTA-376176", "name": "Signaling by ROBO receptors", "reactions": [ "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10048935", "reaction_10089713", "reaction_10090179", "reaction_10048951", "reaction_10043671" ] }, "R-BTA-196108": { "id": "pathway_10093280", "reactome": "R-BTA-196108", "name": "Pregnenolone biosynthesis", "reactions": [ "reaction_10041716", "reaction_10041684", "reaction_10041692" ] }, "R-BTA-445717": { "id": "pathway_10093644", "reactome": "R-BTA-445717", "name": "Aquaporin-mediated transport", "reactions": [ "reaction_10049243", "reaction_10047483", "reaction_10049271", "reaction_10049253", "reaction_10051148", "reaction_10051145", "reaction_10049241", "reaction_10051150", "reaction_10051143", "reaction_10049262", "reaction_10051141", "reaction_10051136" ] }, "R-BTA-909733": { "id": "pathway_10093880", "reactome": "R-BTA-909733", "name": "Interferon alpha/beta signaling", "reactions": [ "reaction_10052229", "reaction_10052217", "reaction_10055955", "reaction_10055958", "reaction_10052189", "reaction_10052213", "reaction_10052196", "reaction_10052236", "reaction_10052159", "reaction_10055946", "reaction_10052210", "reaction_10070719", "reaction_10052147", "reaction_10052347", "reaction_10091725", "reaction_10052233" ] }, "R-BTA-392023": { "id": "pathway_10093612", "reactome": "R-BTA-392023", "name": "Adrenaline signalling through Alpha-2 adrenergic receptor", "reactions": [ "reaction_10047212" ] }, "R-BTA-3214842": { "id": "pathway_10094330", "reactome": "R-BTA-3214842", "name": "HDMs demethylate histones", "reactions": [ "reaction_10073380", "reaction_10069719", "reaction_10073402", "reaction_10069754", "reaction_10073396", "reaction_10073382", "reaction_10069796", "reaction_10073406", "reaction_10073400", "reaction_10069769", "reaction_10073384", "reaction_10069747", "reaction_10073394", "reaction_10073404", "reaction_10066651", "reaction_10069740" ] }, "R-BTA-442755": { "id": "pathway_10092798", "reactome": "R-BTA-442755", "name": "Activation of NMDA receptors and postsynaptic events", "reactions": [ "reaction_10090547", "reaction_10091067", "reaction_10049478", "reaction_10091075", "reaction_10036981" ] }, "R-BTA-194441": { "id": "pathway_10093232", "reactome": "R-BTA-194441", "name": "Metabolism of non-coding RNA", "reactions": [ "reaction_10041050", "reaction_10041039" ] }, "R-BTA-156588": { "id": "pathway_10092924", "reactome": "R-BTA-156588", "name": "Glucuronidation", "reactions": [ "reaction_10039874", "reaction_10038338", "reaction_10038336", "reaction_10039749", "reaction_10039916", "reaction_10076785" ] }, "R-BTA-114604": { "id": "pathway_10092844", "reactome": "R-BTA-114604", "name": "GPVI-mediated activation cascade", "reactions": [ "reaction_10050630", "reaction_10049426", "reaction_10037517", "reaction_10049395", "reaction_10049071", "reaction_10065227", "reaction_10037557", "reaction_10037588" ] }, "R-BTA-1169410": { "id": "pathway_10093972", "reactome": "R-BTA-1169410", "name": "Antiviral mechanism by IFN-stimulated genes", "reactions": [ "reaction_10089703", "reaction_10060730", "reaction_10060732", "reaction_10056315", "reaction_10089341", "reaction_10089696", "reaction_10056289", "reaction_10056283", "reaction_10060694", "reaction_10056287", "reaction_10089349", "reaction_10056297" ] }, "R-BTA-372790": { "id": "pathway_10092780", "reactome": "R-BTA-372790", "name": "Signaling by GPCR", "reactions": [ "reaction_10037037", "reaction_10081580", "reaction_10047236", "reaction_10089211", "reaction_10089207", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10037045", "reaction_10039676", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10047979", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10089224", "reaction_10048587", "reaction_10047334", "reaction_10046149", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10076743", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10037549", "reaction_10037022", "reaction_10083878", "reaction_10048370", "reaction_10047214", "reaction_10083880", "reaction_10039485", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10088942", "reaction_10084702", "reaction_10088940", "reaction_10089228", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10047498", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10064919", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10047823", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10064910", "reaction_10041950", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10046534", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10051656", "reaction_10046731", "reaction_10084016", "reaction_10083951", "reaction_10089222", "reaction_10045292", "reaction_10047947", "reaction_10049659", "reaction_10039671", "reaction_10047366", "reaction_10039674", "reaction_10091763", "reaction_10046729", "reaction_10037330", "reaction_10048304", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10089217", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10037004", "reaction_10049478", "reaction_10048632", "reaction_10051667", "reaction_10048660", "reaction_10039664", "reaction_10049645", "reaction_10049615", "reaction_10043315", "reaction_10046917", "reaction_10047866", "reaction_10039653", "reaction_10047468", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10039667", "reaction_10049643", "reaction_10037332", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10047552", "reaction_10048178", "reaction_10089203", "reaction_10049657", "reaction_10048180", "reaction_10036959", "reaction_10086565", "reaction_10039658", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047956", "reaction_10047380", "reaction_10049681", "reaction_10089197", "reaction_10089214", "reaction_10067358", "reaction_10048170", "reaction_10036981", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10092055", "reaction_10039651", "reaction_10091247", "reaction_10045106" ] }, "R-BTA-209822": { "id": "pathway_10093528", "reactome": "R-BTA-209822", "name": "Glycoprotein hormones", "reactions": [ "reaction_10045696", "reaction_10045736", "reaction_10045744", "reaction_10045694" ] }, "R-BTA-70326": { "id": "pathway_10092474", "reactome": "R-BTA-70326", "name": "Glucose metabolism", "reactions": [ "reaction_10067247", "reaction_10033620", "reaction_10033757", "reaction_10080765", "reaction_10045692", "reaction_10033611", "reaction_10078710", "reaction_10033629", "reaction_10088737", "reaction_10034071", "reaction_10076815", "reaction_10067254", "reaction_10045043", "reaction_10067240", "reaction_10034157", "reaction_10033638", "reaction_10045029", "reaction_10045050", "reaction_10034238", "reaction_10041885", "reaction_10041878", "reaction_10034140", "reaction_10033718" ] }, "R-BTA-189451": { "id": "pathway_10093168", "reactome": "R-BTA-189451", "name": "Heme biosynthesis", "reactions": [ "reaction_10040682", "reaction_10040688", "reaction_10040645", "reaction_10040663", "reaction_10040672", "reaction_10040654", "reaction_10066416" ] }, "R-BTA-190375": { "id": "pathway_10093180", "reactome": "R-BTA-190375", "name": "FGFR2c ligand binding and activation", "reactions": [ "reaction_10040788", "reaction_10040720" ] }, "R-BTA-177128": { "id": "pathway_10092938", "reactome": "R-BTA-177128", "name": "Conjugation of salicylate with glycine", "reactions": [ "reaction_10038380", "reaction_10038382" ] }, "R-BTA-4641263": { "id": "pathway_10094406", "reactome": "R-BTA-4641263", "name": "Regulation of FZD by ubiquitination", "reactions": [ "reaction_10069664", "reaction_10069647", "reaction_10069645" ] }, "R-BTA-8850843": { "id": "pathway_10094748", "reactome": "R-BTA-8850843", "name": "Phosphate bond hydrolysis by NTPDase proteins", "reactions": [ "reaction_10083889", "reaction_10083864", "reaction_10083876", "reaction_10083852", "reaction_10083926", "reaction_10083873", "reaction_10083861" ] }, "R-BTA-9634635": { "id": "pathway_10095006", "reactome": "R-BTA-9634635", "name": "Estrogen-stimulated signaling through PRKCZ", "reactions": [ "reaction_10091271", "reaction_10091260", "reaction_10091275" ] }, "R-BTA-1234158": { "id": "pathway_10093984", "reactome": "R-BTA-1234158", "name": "Regulation of gene expression by Hypoxia-inducible Factor", "reactions": [ "reaction_10056679" ] }, "R-BTA-9696264": { "id": "pathway_10095028", "reactome": "R-BTA-9696264", "name": "RND3 GTPase cycle", "reactions": [ "reaction_10092002", "reaction_10092020" ] }, "R-BTA-1483101": { "id": "pathway_10094114", "reactome": "R-BTA-1483101", "name": "Synthesis of PS", "reactions": [ "reaction_10059073", "reaction_10059121" ] }, "R-BTA-9026290": { "id": "pathway_10094934", "reactome": "R-BTA-9026290", "name": "Biosynthesis of DPAn-3-derived maresins", "reactions": [ "reaction_10090472", "reaction_10090474" ] }, "R-BTA-9711123": { "id": "pathway_10092552", "reactome": "R-BTA-9711123", "name": "Cellular response to chemical stress", "reactions": [ "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10087866", "reaction_10067398", "reaction_10067744", "reaction_10092308", "reaction_10034166", "reaction_10080786", "reaction_10092310", "reaction_10068578", "reaction_10067416", "reaction_10067735", "reaction_10040636", "reaction_10068575", "reaction_10092293", "reaction_10092287", "reaction_10069854", "reaction_10076891", "reaction_10067375", "reaction_10067731", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273", "reaction_10038647", "reaction_10092239", "reaction_10092214", "reaction_10047807" ] }, "R-BTA-432040": { "id": "pathway_10093642", "reactome": "R-BTA-432040", "name": "Vasopressin regulates renal water homeostasis via Aquaporins", "reactions": [ "reaction_10049243", "reaction_10047483", "reaction_10049253", "reaction_10049241", "reaction_10049262" ] }, "R-BTA-9709957": { "id": "pathway_10092630", "reactome": "R-BTA-9709957", "name": "Sensory Perception", "reactions": [ "reaction_10065683", "reaction_10065597", "reaction_10035596", "reaction_10054382", "reaction_10054404", "reaction_10065644", "reaction_10035406", "reaction_10065604", "reaction_10065675", "reaction_10065664", "reaction_10088914", "reaction_10065944", "reaction_10035558", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065445", "reaction_10065673", "reaction_10066247", "reaction_10065437", "reaction_10054393", "reaction_10065441", "reaction_10066249", "reaction_10070971", "reaction_10069948", "reaction_10065679", "reaction_10065606", "reaction_10035619", "reaction_10077751", "reaction_10077744", "reaction_10065940", "reaction_10065677", "reaction_10035579", "reaction_10065808", "reaction_10065646", "reaction_10054375", "reaction_10054395" ] }, "R-BTA-69618": { "id": "pathway_10092900", "reactome": "R-BTA-69618", "name": "Mitotic Spindle Checkpoint", "reactions": [ "reaction_10038033", "reaction_10038035" ] }, "R-BTA-3700989": { "id": "pathway_10092434", "reactome": "R-BTA-3700989", "name": "Transcriptional Regulation by TP53", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10082931", "reaction_10066870", "reaction_10081380", "reaction_10081877", "reaction_10080738", "reaction_10078731", "reaction_10081291", "reaction_10033535", "reaction_10080730", "reaction_10081629", "reaction_10083072", "reaction_10082923", "reaction_10081323", "reaction_10033592", "reaction_10080789", "reaction_10081541", "reaction_10066764", "reaction_10046588", "reaction_10078349", "reaction_10033755", "reaction_10081522", "reaction_10034166", "reaction_10081278", "reaction_10080797", "reaction_10072591", "reaction_10081274", "reaction_10066704", "reaction_10082934", "reaction_10066684", "reaction_10088542", "reaction_10081293", "reaction_10038647", "reaction_10072550", "reaction_10081470", "reaction_10072614", "reaction_10081563", "reaction_10081602", "reaction_10066724", "reaction_10066670", "reaction_10072595", "reaction_10077955", "reaction_10066737", "reaction_10086155", "reaction_10076341", "reaction_10083092", "reaction_10081530", "reaction_10078474", "reaction_10083077", "reaction_10078408", "reaction_10072557", "reaction_10088546", "reaction_10081326", "reaction_10078720", "reaction_10078658", "reaction_10081499", "reaction_10081595", "reaction_10066712", "reaction_10088534", "reaction_10081305", "reaction_10081286", "reaction_10081622", "reaction_10081889", "reaction_10072571", "reaction_10080811", "reaction_10080457", "reaction_10081561" ] }, "R-BTA-163615": { "id": "pathway_10092802", "reactome": "R-BTA-163615", "name": "PKA activation", "reactions": [ "reaction_10037004" ] }, "R-BTA-2142696": { "id": "pathway_10094242", "reactome": "R-BTA-2142696", "name": "Synthesis of Hepoxilins (HX) and Trioxilins (TrX)", "reactions": [ "reaction_10064506" ] }, "R-BTA-69183": { "id": "pathway_10092424", "reactome": "R-BTA-69183", "name": "Processive synthesis on the lagging strand", "reactions": [ "reaction_10033504" ] }, "R-BTA-1614517": { "id": "pathway_10094132", "reactome": "R-BTA-1614517", "name": "Sulfide oxidation to sulfate", "reactions": [ "reaction_10060218", "reaction_10060361", "reaction_10060250", "reaction_10060216" ] }, "R-BTA-9668328": { "id": "pathway_10095014", "reactome": "R-BTA-9668328", "name": "Sealing of the nuclear envelope (NE) by ESCRT-III", "reactions": [ "reaction_10091661", "reaction_10091656", "reaction_10091634", "reaction_10091658" ] }, "R-BTA-73886": { "id": "pathway_10092966", "reactome": "R-BTA-73886", "name": "Chromosome Maintenance", "reactions": [ "reaction_10051465", "reaction_10038947", "reaction_10051451", "reaction_10051463", "reaction_10091663", "reaction_10038540", "reaction_10091685", "reaction_10038534", "reaction_10038949", "reaction_10051461" ] }, "R-BTA-1250196": { "id": "pathway_10094012", "reactome": "R-BTA-1250196", "name": "SHC1 events in ERBB2 signaling", "reactions": [ "reaction_10057139", "reaction_10086415" ] }, "R-BTA-432142": { "id": "pathway_10093418", "reactome": "R-BTA-432142", "name": "Platelet sensitization by LDL", "reactions": [ "reaction_10049283", "reaction_10044018", "reaction_10049290", "reaction_10049364", "reaction_10044043" ] }, "R-BTA-1663150": { "id": "pathway_10094126", "reactome": "R-BTA-1663150", "name": "The activation of arylsulfatases", "reactions": [ "reaction_10060109" ] }, "R-BTA-5654695": { "id": "pathway_10094544", "reactome": "R-BTA-5654695", "name": "PI-3K cascade:FGFR2", "reactions": [ "reaction_10073231" ] }, "R-BTA-9603798": { "id": "pathway_10094970", "reactome": "R-BTA-9603798", "name": "Class I peroxisomal membrane protein import", "reactions": [ "reaction_10090770" ] }, "R-BTA-936837": { "id": "pathway_10093670", "reactome": "R-BTA-936837", "name": "Ion transport by P-type ATPases", "reactions": [ "reaction_10076179", "reaction_10047893", "reaction_10076172", "reaction_10053143", "reaction_10053180", "reaction_10048787", "reaction_10053210", "reaction_10071254", "reaction_10053258", "reaction_10091759", "reaction_10047900" ] }, "R-BTA-1362409": { "id": "pathway_10094072", "reactome": "R-BTA-1362409", "name": "Mitochondrial iron-sulfur cluster biogenesis", "reactions": [ "reaction_10057787", "reaction_10086272", "reaction_10057792" ] }, "R-BTA-388396": { "id": "pathway_10092778", "reactome": "R-BTA-388396", "name": "GPCR downstream signalling", "reactions": [ "reaction_10037037", "reaction_10043315", "reaction_10089211", "reaction_10039653", "reaction_10089207", "reaction_10064915", "reaction_10048580", "reaction_10037045", "reaction_10047468", "reaction_10039676", "reaction_10048543", "reaction_10088940", "reaction_10089228", "reaction_10051656", "reaction_10039667", "reaction_10084016", "reaction_10047979", "reaction_10047498", "reaction_10089224", "reaction_10089222", "reaction_10083951", "reaction_10047947", "reaction_10037332", "reaction_10047552", "reaction_10039671", "reaction_10089203", "reaction_10039674", "reaction_10064919", "reaction_10048587", "reaction_10036959", "reaction_10039664", "reaction_10047823", "reaction_10037330", "reaction_10039658", "reaction_10046149", "reaction_10088962", "reaction_10047956", "reaction_10076743", "reaction_10089226", "reaction_10089167", "reaction_10089214", "reaction_10089197", "reaction_10037024", "reaction_10048170", "reaction_10036981", "reaction_10089217", "reaction_10037549", "reaction_10037022", "reaction_10037004", "reaction_10048370", "reaction_10064910", "reaction_10041950", "reaction_10049478", "reaction_10039485", "reaction_10046534", "reaction_10048632", "reaction_10048660", "reaction_10092055", "reaction_10039651", "reaction_10051667", "reaction_10091247", "reaction_10088942" ] }, "R-BTA-5362517": { "id": "pathway_10093324", "reactome": "R-BTA-5362517", "name": "Signaling by Retinoic Acid", "reactions": [ "reaction_10071407", "reaction_10071659", "reaction_10071648", "reaction_10071668", "reaction_10042860", "reaction_10071678", "reaction_10072397", "reaction_10044211", "reaction_10071691", "reaction_10072630", "reaction_10076840", "reaction_10072433", "reaction_10072628", "reaction_10072225", "reaction_10071397", "reaction_10071673" ] }, "R-BTA-202424": { "id": "pathway_10093348", "reactome": "R-BTA-202424", "name": "Downstream TCR signaling", "reactions": [ "reaction_10043219", "reaction_10043212", "reaction_10043302", "reaction_10043300", "reaction_10043298", "reaction_10043193", "reaction_10043270", "reaction_10043304", "reaction_10043252", "reaction_10043244", "reaction_10043225", "reaction_10043182", "reaction_10043274" ] }, "R-BTA-8957275": { "id": "pathway_10094846", "reactome": "R-BTA-8957275", "name": "Post-translational protein phosphorylation", "reactions": [ "reaction_10088473" ] }, "R-BTA-1592389": { "id": "pathway_10094118", "reactome": "R-BTA-1592389", "name": "Activation of Matrix Metalloproteinases", "reactions": [ "reaction_10059902", "reaction_10059913", "reaction_10059744", "reaction_10060003", "reaction_10059689", "reaction_10059918", "reaction_10059731", "reaction_10059869", "reaction_10059787", "reaction_10059923", "reaction_10059804" ] }, "R-BTA-6807047": { "id": "pathway_10093278", "reactome": "R-BTA-6807047", "name": "Cholesterol biosynthesis via desmosterol", "reactions": [ "reaction_10041664", "reaction_10041728", "reaction_10041671" ] }, "R-BTA-3134963": { "id": "pathway_10094328", "reactome": "R-BTA-3134963", "name": "DEx/H-box helicases activate type I IFN and inflammatory cytokines production ", "reactions": [ "reaction_10090837", "reaction_10066559" ] }, "R-BTA-194315": { "id": "pathway_10093368", "reactome": "R-BTA-194315", "name": "Signaling by Rho GTPases", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10072515", "reaction_10073503", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] }, "R-BTA-2565942": { "id": "pathway_10094312", "reactome": "R-BTA-2565942", "name": "Regulation of PLK1 Activity at G2/M Transition", "reactions": [ "reaction_10066489", "reaction_10066487", "reaction_10065938" ] }, "R-BTA-451308": { "id": "pathway_10093812", "reactome": "R-BTA-451308", "name": "Activation of Ca-permeable Kainate Receptor", "reactions": [ "reaction_10050514", "reaction_10050517" ] }, "R-BTA-2173795": { "id": "pathway_10094270", "reactome": "R-BTA-2173795", "name": "Downregulation of SMAD2/3:SMAD4 transcriptional activity", "reactions": [ "reaction_10064933" ] }, "R-BTA-5213460": { "id": "pathway_10094368", "reactome": "R-BTA-5213460", "name": "RIPK1-mediated regulated necrosis", "reactions": [ "reaction_10091779", "reaction_10070684", "reaction_10070534", "reaction_10070689", "reaction_10091773", "reaction_10072346", "reaction_10074254", "reaction_10091793", "reaction_10070531", "reaction_10071534", "reaction_10091808", "reaction_10074240", "reaction_10091806", "reaction_10068030", "reaction_10091810", "reaction_10070682", "reaction_10091783" ] }, "R-BTA-5621480": { "id": "pathway_10094492", "reactome": "R-BTA-5621480", "name": "Dectin-2 family", "reactions": [ "reaction_10072364", "reaction_10072383", "reaction_10072388", "reaction_10072392", "reaction_10072374", "reaction_10084636", "reaction_10072395" ] }, "R-BTA-1855183": { "id": "pathway_10094170", "reactome": "R-BTA-1855183", "name": "Synthesis of IP2, IP, and Ins in the cytosol", "reactions": [ "reaction_10061067", "reaction_10060938", "reaction_10061046", "reaction_10060986", "reaction_10061061", "reaction_10061064", "reaction_10061014", "reaction_10061134" ] }, "R-BTA-8847453": { "id": "pathway_10094696", "reactome": "R-BTA-8847453", "name": "Synthesis of PIPs in the nucleus", "reactions": [ "reaction_10082931", "reaction_10082934", "reaction_10083092" ] }, "R-BTA-69563": { "id": "pathway_10092444", "reactome": "R-BTA-69563", "name": "p53-Dependent G1 DNA Damage Response", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-193048": { "id": "pathway_10093254", "reactome": "R-BTA-193048", "name": "Androgen biosynthesis", "reactions": [ "reaction_10050650", "reaction_10041293", "reaction_10092065", "reaction_10041295", "reaction_10041290", "reaction_10041297", "reaction_10041284", "reaction_10092062" ] }, "R-BTA-382556": { "id": "pathway_10093468", "reactome": "R-BTA-382556", "name": "ABC-family proteins mediated transport", "reactions": [ "reaction_10074686", "reaction_10058216", "reaction_10074360", "reaction_10070728", "reaction_10058469", "reaction_10046707", "reaction_10046698", "reaction_10074493", "reaction_10057832", "reaction_10070743", "reaction_10044666" ] }, "R-BTA-6804760": { "id": "pathway_10094338", "reactome": "R-BTA-6804760", "name": "Regulation of TP53 Activity through Methylation", "reactions": [ "reaction_10066737", "reaction_10081877" ] }, "R-BTA-912694": { "id": "pathway_10093950", "reactome": "R-BTA-912694", "name": "Regulation of IFNA signaling", "reactions": [ "reaction_10055946", "reaction_10055955", "reaction_10055958" ] }, "R-BTA-8866910": { "id": "pathway_10093534", "reactome": "R-BTA-8866910", "name": "TFAP2 (AP-2) family regulates transcription of growth factors and their receptors", "reactions": [ "reaction_10045744" ] }, "R-BTA-112399": { "id": "pathway_10092640", "reactome": "R-BTA-112399", "name": "IRS-mediated signalling", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-2173796": { "id": "pathway_10094440", "reactome": "R-BTA-2173796", "name": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription", "reactions": [ "reaction_10071262" ] }, "R-BTA-5357786": { "id": "pathway_10092878", "reactome": "R-BTA-5357786", "name": "TNFR1-induced proapoptotic signaling", "reactions": [ "reaction_10037964" ] }, "R-BTA-8964539": { "id": "pathway_10092492", "reactome": "R-BTA-8964539", "name": "Glutamate and glutamine metabolism", "reactions": [ "reaction_10051165", "reaction_10033755", "reaction_10033757", "reaction_10033746", "reaction_10052046", "reaction_10077444", "reaction_10087455", "reaction_10077453" ] }, "R-BTA-193634": { "id": "pathway_10093266", "reactome": "R-BTA-193634", "name": "Axonal growth inhibition (RHOA activation)", "reactions": [ "reaction_10041470" ] }, "R-BTA-2173793": { "id": "pathway_10094272", "reactome": "R-BTA-2173793", "name": "Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer", "reactions": [ "reaction_10064933", "reaction_10071262" ] }, "R-BTA-75105": { "id": "pathway_10093332", "reactome": "R-BTA-75105", "name": "Fatty acyl-CoA biosynthesis", "reactions": [ "reaction_10042961", "reaction_10083389", "reaction_10051252", "reaction_10074353", "reaction_10051261" ] }, "R-BTA-2485179": { "id": "pathway_10092624", "reactome": "R-BTA-2485179", "name": "Activation of the phototransduction cascade", "reactions": [ "reaction_10035406" ] }, "R-BTA-1169092": { "id": "pathway_10093964", "reactome": "R-BTA-1169092", "name": "Activation of RAS in B cells", "reactions": [ "reaction_10056239" ] }, "R-BTA-1442490": { "id": "pathway_10094076", "reactome": "R-BTA-1442490", "name": "Collagen degradation", "reactions": [ "reaction_10059441", "reaction_10064649", "reaction_10076984", "reaction_10059651", "reaction_10059598", "reaction_10058193", "reaction_10059533", "reaction_10058561", "reaction_10064705" ] }, "R-BTA-73857": { "id": "pathway_10092438", "reactome": "R-BTA-73857", "name": "RNA Polymerase II Transcription", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10037185", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10037201", "reaction_10087900", "reaction_10088482", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-1253288": { "id": "pathway_10094022", "reactome": "R-BTA-1253288", "name": "Downregulation of ERBB4 signaling", "reactions": [ "reaction_10057262", "reaction_10090971", "reaction_10057264" ] }, "R-BTA-187015": { "id": "pathway_10093014", "reactome": "R-BTA-187015", "name": "Activation of TRKA receptors", "reactions": [ "reaction_10039270", "reaction_10039272", "reaction_10040684" ] }, "R-BTA-901032": { "id": "pathway_10093952", "reactome": "R-BTA-901032", "name": "ER Quality Control Compartment (ERQC)", "reactions": [ "reaction_10056058" ] }, "R-BTA-8866904": { "id": "pathway_10094784", "reactome": "R-BTA-8866904", "name": "Negative regulation of activity of TFAP2 (AP-2) family transcription factors", "reactions": [ "reaction_10084903", "reaction_10084909" ] }, "R-BTA-5684996": { "id": "pathway_10094570", "reactome": "R-BTA-5684996", "name": "MAPK1/MAPK3 signaling", "reactions": [ "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10091490", "reaction_10073904", "reaction_10091506", "reaction_10073932", "reaction_10074238", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10074088", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10073940", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-1358803": { "id": "pathway_10094068", "reactome": "R-BTA-1358803", "name": "Downregulation of ERBB2:ERBB3 signaling", "reactions": [ "reaction_10057712", "reaction_10057735", "reaction_10057740", "reaction_10057719", "reaction_10057742", "reaction_10057744" ] }, "R-BTA-3928665": { "id": "pathway_10094392", "reactome": "R-BTA-3928665", "name": "EPH-ephrin mediated repulsion of cells", "reactions": [ "reaction_10069285", "reaction_10069159", "reaction_10069157" ] }, "R-BTA-5661231": { "id": "pathway_10094550", "reactome": "R-BTA-5661231", "name": "Metallothioneins bind metals", "reactions": [ "reaction_10073446", "reaction_10073481", "reaction_10073460", "reaction_10073468", "reaction_10073464" ] }, "R-BTA-418592": { "id": "pathway_10093662", "reactome": "R-BTA-418592", "name": "ADP signalling through P2Y purinoceptor 1", "reactions": [ "reaction_10049039", "reaction_10047985", "reaction_10047870" ] }, "R-BTA-77346": { "id": "pathway_10092716", "reactome": "R-BTA-77346", "name": "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA", "reactions": [ "reaction_10036040", "reaction_10036042" ] }, "R-BTA-168142": { "id": "pathway_10093036", "reactome": "R-BTA-168142", "name": "Toll Like Receptor 10 (TLR10) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-3000171": { "id": "pathway_10094280", "reactome": "R-BTA-3000171", "name": "Non-integrin membrane-ECM interactions", "reactions": [ "reaction_10065292" ] }, "R-BTA-193368": { "id": "pathway_10093238", "reactome": "R-BTA-193368", "name": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol", "reactions": [ "reaction_10041197", "reaction_10041172", "reaction_10041308", "reaction_10041177", "reaction_10041208", "reaction_10041104", "reaction_10041226", "reaction_10041323", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041327", "reaction_10041210", "reaction_10041317", "reaction_10041204", "reaction_10041319", "reaction_10041179", "reaction_10041301" ] }, "R-BTA-390651": { "id": "pathway_10093614", "reactome": "R-BTA-390651", "name": "Dopamine receptors", "reactions": [ "reaction_10091556", "reaction_10047224", "reaction_10047222" ] }, "R-BTA-2404192": { "id": "pathway_10092652", "reactome": "R-BTA-2404192", "name": "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)", "reactions": [ "reaction_10075063", "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-6806003": { "id": "pathway_10094334", "reactome": "R-BTA-6806003", "name": "Regulation of TP53 Expression and Degradation", "reactions": [ "reaction_10066684", "reaction_10081541", "reaction_10078408", "reaction_10081561" ] }, "R-BTA-109581": { "id": "pathway_10092620", "reactome": "R-BTA-109581", "name": "Apoptosis", "reactions": [ "reaction_10044568", "reaction_10044116", "reaction_10043049", "reaction_10068042", "reaction_10037731", "reaction_10037991", "reaction_10044146", "reaction_10051175", "reaction_10037678", "reaction_10043039", "reaction_10044756", "reaction_10037706", "reaction_10037618", "reaction_10037253", "reaction_10044762", "reaction_10068046", "reaction_10044995", "reaction_10044896", "reaction_10044927", "reaction_10044869", "reaction_10037723", "reaction_10091191", "reaction_10035396", "reaction_10044578", "reaction_10037702", "reaction_10037277", "reaction_10091197", "reaction_10037293", "reaction_10081897", "reaction_10037630", "reaction_10067891", "reaction_10038007", "reaction_10044142", "reaction_10091186", "reaction_10091188", "reaction_10051181", "reaction_10043059", "reaction_10044680", "reaction_10037739", "reaction_10037237", "reaction_10043021", "reaction_10090573", "reaction_10037674", "reaction_10039520", "reaction_10044923", "reaction_10090575", "reaction_10037289", "reaction_10037264", "reaction_10037727", "reaction_10037985", "reaction_10044144", "reaction_10037622", "reaction_10044906", "reaction_10067895", "reaction_10037641" ] }, "R-BTA-1963642": { "id": "pathway_10094064", "reactome": "R-BTA-1963642", "name": "PI3K events in ERBB2 signaling", "reactions": [ "reaction_10057700" ] }, "R-BTA-913531": { "id": "pathway_10093860", "reactome": "R-BTA-913531", "name": "Interferon Signaling", "reactions": [ "reaction_10052229", "reaction_10052217", "reaction_10052213", "reaction_10056315", "reaction_10051762", "reaction_10091723", "reaction_10089341", "reaction_10051696", "reaction_10089703", "reaction_10051818", "reaction_10055955", "reaction_10060730", "reaction_10055958", "reaction_10051792", "reaction_10089696", "reaction_10056289", "reaction_10052159", "reaction_10055946", "reaction_10051737", "reaction_10070719", "reaction_10056283", "reaction_10055967", "reaction_10052233", "reaction_10052189", "reaction_10052196", "reaction_10052236", "reaction_10051786", "reaction_10052067", "reaction_10089349", "reaction_10060694", "reaction_10056287", "reaction_10052210", "reaction_10052147", "reaction_10051780", "reaction_10051748", "reaction_10051771", "reaction_10060732", "reaction_10051774", "reaction_10056297", "reaction_10052347", "reaction_10091725" ] }, "R-BTA-156581": { "id": "pathway_10092694", "reactome": "R-BTA-156581", "name": "Methylation", "reactions": [ "reaction_10035863", "reaction_10071924", "reaction_10076900", "reaction_10038238", "reaction_10039930", "reaction_10076903", "reaction_10076898" ] }, "R-BTA-109582": { "id": "pathway_10092842", "reactome": "R-BTA-109582", "name": "Hemostasis", "reactions": [ "reaction_10037913", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10090718", "reaction_10049300", "reaction_10047475", "reaction_10053213", "reaction_10038303", "reaction_10047893", "reaction_10048587", "reaction_10043323", "reaction_10038329", "reaction_10050994", "reaction_10055920", "reaction_10076743", "reaction_10037927", "reaction_10043375", "reaction_10037353", "reaction_10056002", "reaction_10038201", "reaction_10048635", "reaction_10037852", "reaction_10049071", "reaction_10091701", "reaction_10055831", "reaction_10091546", "reaction_10037588", "reaction_10055833", "reaction_10071906", "reaction_10037895", "reaction_10038307", "reaction_10055649", "reaction_10043363", "reaction_10071946", "reaction_10051002", "reaction_10043355", "reaction_10037923", "reaction_10037948", "reaction_10044030", "reaction_10038288", "reaction_10049279", "reaction_10055823", "reaction_10085323", "reaction_10065227", "reaction_10037557", "reaction_10037800", "reaction_10037937", "reaction_10037899", "reaction_10037915", "reaction_10049039", "reaction_10047212", "reaction_10055870", "reaction_10055647", "reaction_10049506", "reaction_10037433", "reaction_10055827", "reaction_10047857", "reaction_10038213", "reaction_10055515", "reaction_10092299", "reaction_10048580", "reaction_10048543", "reaction_10050870", "reaction_10044043", "reaction_10038285", "reaction_10037845", "reaction_10048504", "reaction_10048182", "reaction_10055995", "reaction_10055933", "reaction_10044039", "reaction_10047930", "reaction_10038270", "reaction_10038290", "reaction_10038263", "reaction_10037517", "reaction_10043347", "reaction_10055829", "reaction_10037887", "reaction_10066263", "reaction_10047900", "reaction_10049283", "reaction_10044018", "reaction_10051062", "reaction_10037607", "reaction_10055645", "reaction_10038221", "reaction_10044034", "reaction_10048632", "reaction_10037950", "reaction_10037815", "reaction_10048660", "reaction_10038166", "reaction_10037580", "reaction_10055529", "reaction_10049364", "reaction_10049067", "reaction_10037906", "reaction_10050630", "reaction_10049290", "reaction_10090183", "reaction_10043335", "reaction_10090181", "reaction_10049014", "reaction_10038205", "reaction_10050948", "reaction_10047907", "reaction_10043397", "reaction_10049035", "reaction_10044024", "reaction_10049426", "reaction_10049395", "reaction_10047870", "reaction_10047880", "reaction_10047380", "reaction_10090185", "reaction_10045016", "reaction_10055847", "reaction_10091671", "reaction_10047985", "reaction_10047886", "reaction_10044020", "reaction_10043393", "reaction_10050924", "reaction_10085753", "reaction_10038292" ] }, "R-BTA-383280": { "id": "pathway_10093556", "reactome": "R-BTA-383280", "name": "Nuclear Receptor transcription pathway", "reactions": [ "reaction_10046681" ] }, "R-BTA-2408508": { "id": "pathway_10094286", "reactome": "R-BTA-2408508", "name": "Metabolism of ingested SeMet, Sec, MeSec into H2Se", "reactions": [ "reaction_10065455" ] }, "R-BTA-1300645": { "id": "pathway_10094046", "reactome": "R-BTA-1300645", "name": "Acrosome Reaction and Sperm:Oocyte Membrane Binding", "reactions": [ "reaction_10057605", "reaction_10057598" ] }, "R-BTA-1483255": { "id": "pathway_10094144", "reactome": "R-BTA-1483255", "name": "PI Metabolism", "reactions": [ "reaction_10060537", "reaction_10082931", "reaction_10060550", "reaction_10082147", "reaction_10060473", "reaction_10085697", "reaction_10060516", "reaction_10082136", "reaction_10060572", "reaction_10060518", "reaction_10060514", "reaction_10060611", "reaction_10082152", "reaction_10060614", "reaction_10085784", "reaction_10082155", "reaction_10060483", "reaction_10060468", "reaction_10060569", "reaction_10085780", "reaction_10082934", "reaction_10060501", "reaction_10060553", "reaction_10060597", "reaction_10060600", "reaction_10060595", "reaction_10060590", "reaction_10083092", "reaction_10060574", "reaction_10060558", "reaction_10060588", "reaction_10060476", "reaction_10060579", "reaction_10083800", "reaction_10060556", "reaction_10085775", "reaction_10085843", "reaction_10060448", "reaction_10060429", "reaction_10083369", "reaction_10060461", "reaction_10083211", "reaction_10060498", "reaction_10060535" ] }, "R-BTA-9033807": { "id": "pathway_10094958", "reactome": "R-BTA-9033807", "name": "ABO blood group biosynthesis", "reactions": [ "reaction_10090620", "reaction_10090631", "reaction_10090611", "reaction_10090645", "reaction_10090703", "reaction_10090638" ] }, "R-BTA-5654706": { "id": "pathway_10094528", "reactome": "R-BTA-5654706", "name": "FRS-mediated FGFR3 signaling", "reactions": [ "reaction_10073014", "reaction_10073021", "reaction_10073147", "reaction_10073011", "reaction_10087376", "reaction_10073019", "reaction_10073145" ] }, "R-BTA-187037": { "id": "pathway_10093016", "reactome": "R-BTA-187037", "name": "Signaling by NTRK1 (TRKA)", "reactions": [ "reaction_10090994", "reaction_10039272", "reaction_10043315", "reaction_10041917", "reaction_10041869", "reaction_10039601", "reaction_10039736", "reaction_10041851", "reaction_10040570", "reaction_10039270", "reaction_10042826", "reaction_10039581", "reaction_10040684", "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090954", "reaction_10074879", "reaction_10039592", "reaction_10041950", "reaction_10090944", "reaction_10043488", "reaction_10039711" ] }, "R-BTA-5576886": { "id": "pathway_10094038", "reactome": "R-BTA-5576886", "name": "Phase 4 - resting membrane potential", "reactions": [ "reaction_10071876", "reaction_10057418" ] }, "R-BTA-444411": { "id": "pathway_10093770", "reactome": "R-BTA-444411", "name": "Rhesus glycoproteins mediate ammonium transport.", "reactions": [ "reaction_10049635", "reaction_10049871", "reaction_10049869", "reaction_10049628" ] }, "R-BTA-171319": { "id": "pathway_10092960", "reactome": "R-BTA-171319", "name": "Telomere Extension By Telomerase", "reactions": [ "reaction_10038534", "reaction_10038947", "reaction_10038540", "reaction_10038949" ] }, "R-BTA-5607761": { "id": "pathway_10094468", "reactome": "R-BTA-5607761", "name": "Dectin-1 mediated noncanonical NF-kB signaling", "reactions": [ "reaction_10072030", "reaction_10071975", "reaction_10071948", "reaction_10071982" ] }, "R-BTA-110330": { "id": "pathway_10095004", "reactome": "R-BTA-110330", "name": "Recognition and association of DNA glycosylase with site containing an affected purine", "reactions": [ "reaction_10091211", "reaction_10091566" ] }, "R-BTA-6814848": { "id": "pathway_10094714", "reactome": "R-BTA-6814848", "name": "Glycerophospholipid catabolism", "reactions": [ "reaction_10083211", "reaction_10083369" ] }, "R-BTA-2871796": { "id": "pathway_10093048", "reactome": "R-BTA-2871796", "name": "FCERI mediated MAPK activation", "reactions": [ "reaction_10050208", "reaction_10066151", "reaction_10066082", "reaction_10066065", "reaction_10039508", "reaction_10065491", "reaction_10050256" ] }, "R-BTA-8849471": { "id": "pathway_10094736", "reactome": "R-BTA-8849471", "name": "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases", "reactions": [ "reaction_10083690", "reaction_10083629", "reaction_10083695", "reaction_10083684", "reaction_10083622", "reaction_10083588", "reaction_10083697", "reaction_10083581" ] }, "R-BTA-76046": { "id": "pathway_10092684", "reactome": "R-BTA-76046", "name": "RNA Polymerase III Transcription Initiation", "reactions": [ "reaction_10035854" ] }, "R-BTA-418555": { "id": "pathway_10093680", "reactome": "R-BTA-418555", "name": "G alpha (s) signalling events", "reactions": [ "reaction_10083951", "reaction_10047947", "reaction_10089226", "reaction_10092055", "reaction_10089228", "reaction_10091247", "reaction_10084016" ] }, "R-BTA-9007101": { "id": "pathway_10094766", "reactome": "R-BTA-9007101", "name": "Rab regulation of trafficking", "reactions": [ "reaction_10085988", "reaction_10084238", "reaction_10086097", "reaction_10084291", "reaction_10086136", "reaction_10084276", "reaction_10085932", "reaction_10084246", "reaction_10086209", "reaction_10084261", "reaction_10084228", "reaction_10086019", "reaction_10086182", "reaction_10086054" ] }, "R-BTA-73884": { "id": "pathway_10092754", "reactome": "R-BTA-73884", "name": "Base Excision Repair", "reactions": [ "reaction_10036716", "reaction_10091566", "reaction_10091222", "reaction_10088526", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036767", "reaction_10036709", "reaction_10091211", "reaction_10036729", "reaction_10036798", "reaction_10036736", "reaction_10091233", "reaction_10091240", "reaction_10036743", "reaction_10036805" ] }, "R-BTA-390466": { "id": "pathway_10094718", "reactome": "R-BTA-390466", "name": "Chaperonin-mediated protein folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-5656169": { "id": "pathway_10094502", "reactome": "R-BTA-5656169", "name": "Termination of translesion DNA synthesis", "reactions": [ "reaction_10072883", "reaction_10072876", "reaction_10073302" ] }, "R-BTA-5653890": { "id": "pathway_10094504", "reactome": "R-BTA-5653890", "name": "Lactose synthesis", "reactions": [ "reaction_10072894", "reaction_10072898" ] }, "R-BTA-982772": { "id": "pathway_10093942", "reactome": "R-BTA-982772", "name": "Growth hormone receptor signaling", "reactions": [ "reaction_10056268", "reaction_10054779", "reaction_10054791" ] }, "R-BTA-400508": { "id": "pathway_10093562", "reactome": "R-BTA-400508", "name": "Incretin synthesis, secretion, and inactivation", "reactions": [ "reaction_10046723", "reaction_10048380" ] }, "R-BTA-5357769": { "id": "pathway_10092618", "reactome": "R-BTA-5357769", "name": "Caspase activation via extrinsic apoptotic signalling pathway", "reactions": [ "reaction_10068046", "reaction_10035396", "reaction_10068042", "reaction_10037991", "reaction_10037985", "reaction_10067895", "reaction_10067891" ] }, "R-BTA-8964058": { "id": "pathway_10093456", "reactome": "R-BTA-8964058", "name": "HDL remodeling", "reactions": [ "reaction_10044666", "reaction_10088982", "reaction_10044547" ] }, "R-BTA-169893": { "id": "pathway_10093080", "reactome": "R-BTA-169893", "name": "Prolonged ERK activation events", "reactions": [ "reaction_10090949", "reaction_10039601", "reaction_10039697", "reaction_10039581", "reaction_10039690", "reaction_10039592", "reaction_10090944", "reaction_10090954", "reaction_10039711" ] }, "R-BTA-8963889": { "id": "pathway_10094636", "reactome": "R-BTA-8963889", "name": "Assembly of active LPL and LIPC lipase complexes", "reactions": [ "reaction_10084509", "reaction_10077487", "reaction_10077489" ] }, "R-BTA-70895": { "id": "pathway_10092508", "reactome": "R-BTA-70895", "name": "Branched-chain amino acid catabolism", "reactions": [ "reaction_10033824", "reaction_10051185", "reaction_10033788", "reaction_10033797", "reaction_10033806" ] }, "R-BTA-6783310": { "id": "pathway_10094638", "reactome": "R-BTA-6783310", "name": "Fanconi Anemia Pathway", "reactions": [ "reaction_10077625", "reaction_10077593", "reaction_10077591" ] }, "R-BTA-5661270": { "id": "pathway_10094548", "reactome": "R-BTA-5661270", "name": "Formation of xylulose-5-phosphate", "reactions": [ "reaction_10073431", "reaction_10073438" ] }, "R-BTA-975577": { "id": "pathway_10093930", "reactome": "R-BTA-975577", "name": "N-Glycan antennae elongation", "reactions": [ "reaction_10056061", "reaction_10054418", "reaction_10054431", "reaction_10056074", "reaction_10054438", "reaction_10054467" ] }, "R-BTA-435354": { "id": "pathway_10093762", "reactome": "R-BTA-435354", "name": "Zinc transporters", "reactions": [ "reaction_10049392", "reaction_10049378", "reaction_10049440", "reaction_10049385", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-5693538": { "id": "pathway_10092680", "reactome": "R-BTA-5693538", "name": "Homology Directed Repair", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075306", "reaction_10074798", "reaction_10075151", "reaction_10075326", "reaction_10075304", "reaction_10076339", "reaction_10075037", "reaction_10035846", "reaction_10075181", "reaction_10075323", "reaction_10075319" ] }, "R-BTA-156842": { "id": "pathway_10092910", "reactome": "R-BTA-156842", "name": "Eukaryotic Translation Elongation", "reactions": [ "reaction_10038107" ] }, "R-BTA-379398": { "id": "pathway_10093538", "reactome": "R-BTA-379398", "name": "Enzymatic degradation of Dopamine by monoamine oxidase", "reactions": [ "reaction_10046151" ] }, "R-BTA-5358606": { "id": "pathway_10094454", "reactome": "R-BTA-5358606", "name": "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)", "reactions": [ "reaction_10071617", "reaction_10071765", "reaction_10071630" ] }, "R-BTA-6807062": { "id": "pathway_10094690", "reactome": "R-BTA-6807062", "name": "Cholesterol biosynthesis via lathosterol", "reactions": [ "reaction_10081990", "reaction_10081988", "reaction_10081986" ] }, "R-BTA-76009": { "id": "pathway_10093494", "reactome": "R-BTA-76009", "name": "Platelet Aggregation (Plug Formation)", "reactions": [ "reaction_10047212", "reaction_10053213", "reaction_10049506", "reaction_10045016", "reaction_10049279" ] }, "R-BTA-5654696": { "id": "pathway_10094508", "reactome": "R-BTA-5654696", "name": "Downstream signaling of activated FGFR2", "reactions": [ "reaction_10073133", "reaction_10073127", "reaction_10073129", "reaction_10087370", "reaction_10072931", "reaction_10072979", "reaction_10072976", "reaction_10073231", "reaction_10072929", "reaction_10073136", "reaction_10072999", "reaction_10072909", "reaction_10072993", "reaction_10073001", "reaction_10073004" ] }, "R-BTA-3249367": { "id": "pathway_10094344", "reactome": "R-BTA-3249367", "name": "STAT6-mediated induction of chemokines", "reactions": [ "reaction_10067233", "reaction_10067223", "reaction_10067216", "reaction_10067231", "reaction_10067229", "reaction_10067225" ] }, "R-BTA-9020558": { "id": "pathway_10093818", "reactome": "R-BTA-9020558", "name": "Interleukin-2 signaling", "reactions": [ "reaction_10051196", "reaction_10051194", "reaction_10091731", "reaction_10050527" ] }, "R-BTA-1237112": { "id": "pathway_10094006", "reactome": "R-BTA-1237112", "name": "Methionine salvage pathway", "reactions": [ "reaction_10057023", "reaction_10057684", "reaction_10057032" ] }, "R-BTA-1299361": { "id": "pathway_10094060", "reactome": "R-BTA-1299361", "name": "TWIK-related alkaline pH activated K+ channel (TALK)", "reactions": [ "reaction_10057682" ] }, "R-BTA-4419969": { "id": "pathway_10094400", "reactome": "R-BTA-4419969", "name": "Depolymerisation of the Nuclear Lamina", "reactions": [ "reaction_10070705", "reaction_10069491" ] }, "R-BTA-9617629": { "id": "pathway_10094992", "reactome": "R-BTA-9617629", "name": "Regulation of FOXO transcriptional activity by acetylation", "reactions": [ "reaction_10091096", "reaction_10091184", "reaction_10091089" ] }, "R-BTA-879518": { "id": "pathway_10093870", "reactome": "R-BTA-879518", "name": "Transport of organic anions", "reactions": [ "reaction_10051879", "reaction_10051866", "reaction_10051899", "reaction_10051843", "reaction_10091250" ] }, "R-BTA-74182": { "id": "pathway_10092610", "reactome": "R-BTA-74182", "name": "Ketone body metabolism", "reactions": [ "reaction_10035374", "reaction_10035415", "reaction_10035372", "reaction_10035363", "reaction_10035417" ] }, "R-BTA-5654743": { "id": "pathway_10093198", "reactome": "R-BTA-5654743", "name": "Signaling by FGFR4", "reactions": [ "reaction_10057327", "reaction_10072939", "reaction_10073222", "reaction_10040769", "reaction_10073192", "reaction_10073240", "reaction_10057314", "reaction_10057329", "reaction_10040776", "reaction_10087367", "reaction_10059156", "reaction_10053082", "reaction_10073166", "reaction_10057707", "reaction_10073044", "reaction_10057318", "reaction_10073175", "reaction_10073037", "reaction_10072933", "reaction_10057704", "reaction_10073031", "reaction_10073237", "reaction_10073184", "reaction_10073246", "reaction_10073177", "reaction_10073028", "reaction_10072927", "reaction_10073182", "reaction_10057323", "reaction_10073047", "reaction_10057337", "reaction_10073041", "reaction_10057302" ] }, "R-BTA-1606322": { "id": "pathway_10094208", "reactome": "R-BTA-1606322", "name": "ZBP1(DAI) mediated induction of type I IFNs", "reactions": [ "reaction_10065388", "reaction_10063376" ] }, "R-BTA-193639": { "id": "pathway_10093404", "reactome": "R-BTA-193639", "name": "p75NTR signals via NF-kB", "reactions": [ "reaction_10043877" ] }, "R-BTA-5675221": { "id": "pathway_10094576", "reactome": "R-BTA-5675221", "name": "Negative regulation of MAPK pathway", "reactions": [ "reaction_10074146", "reaction_10074231", "reaction_10074156", "reaction_10074184", "reaction_10074238", "reaction_10074148", "reaction_10074221" ] }, "R-BTA-202733": { "id": "pathway_10093362", "reactome": "R-BTA-202733", "name": "Cell surface interactions at the vascular wall", "reactions": [ "reaction_10044024", "reaction_10043347", "reaction_10044018", "reaction_10043375", "reaction_10066263", "reaction_10043363", "reaction_10044030", "reaction_10044034", "reaction_10043397", "reaction_10043393", "reaction_10044039", "reaction_10043355", "reaction_10043335", "reaction_10085753", "reaction_10044043", "reaction_10043323" ] }, "R-BTA-804914": { "id": "pathway_10093872", "reactome": "R-BTA-804914", "name": "Transport of fatty acids", "reactions": [ "reaction_10051892", "reaction_10070928" ] }, "R-BTA-561048": { "id": "pathway_10093834", "reactome": "R-BTA-561048", "name": "Organic anion transport", "reactions": [ "reaction_10051314", "reaction_10051305" ] }, "R-BTA-187687": { "id": "pathway_10093082", "reactome": "R-BTA-187687", "name": "Signalling to ERKs", "reactions": [ "reaction_10090949", "reaction_10039601", "reaction_10039697", "reaction_10039581", "reaction_10039690", "reaction_10039592", "reaction_10039736", "reaction_10040570", "reaction_10090944", "reaction_10090954", "reaction_10039711", "reaction_10074879" ] }, "R-BTA-1614558": { "id": "pathway_10094134", "reactome": "R-BTA-1614558", "name": "Degradation of cysteine and homocysteine", "reactions": [ "reaction_10060361", "reaction_10060250", "reaction_10060234", "reaction_10060216", "reaction_10060255", "reaction_10060228", "reaction_10060252", "reaction_10089959", "reaction_10060264", "reaction_10089850", "reaction_10090013", "reaction_10083204", "reaction_10090015", "reaction_10090671", "reaction_10060218", "reaction_10090679", "reaction_10090681" ] }, "R-BTA-5682910": { "id": "pathway_10094584", "reactome": "R-BTA-5682910", "name": "LGI-ADAM interactions", "reactions": [ "reaction_10074603", "reaction_10074613", "reaction_10074641" ] }, "R-BTA-1369062": { "id": "pathway_10093466", "reactome": "R-BTA-1369062", "name": "ABC transporters in lipid homeostasis", "reactions": [ "reaction_10074686", "reaction_10074493", "reaction_10044666", "reaction_10046707" ] }, "R-BTA-1502540": { "id": "pathway_10093974", "reactome": "R-BTA-1502540", "name": "Signaling by Activin", "reactions": [ "reaction_10056356", "reaction_10056354" ] }, "R-BTA-168181": { "id": "pathway_10093030", "reactome": "R-BTA-168181", "name": "Toll Like Receptor 7/8 (TLR7/8) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10091739", "reaction_10043488", "reaction_10039508", "reaction_10050256", "reaction_10050231", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-391908": { "id": "pathway_10093628", "reactome": "R-BTA-391908", "name": "Prostanoid ligand receptors", "reactions": [ "reaction_10047374", "reaction_10047394", "reaction_10047366", "reaction_10047380", "reaction_10047376" ] }, "R-BTA-111885": { "id": "pathway_10092774", "reactome": "R-BTA-111885", "name": "Opioid Signalling", "reactions": [ "reaction_10037037", "reaction_10037022", "reaction_10037004", "reaction_10039653", "reaction_10036981", "reaction_10039671", "reaction_10037045", "reaction_10039674", "reaction_10049478", "reaction_10039485", "reaction_10039676", "reaction_10036959", "reaction_10039651", "reaction_10037024", "reaction_10039667", "reaction_10039658", "reaction_10039664" ] }, "R-BTA-6805567": { "id": "pathway_10094654", "reactome": "R-BTA-6805567", "name": "Keratinization", "reactions": [ "reaction_10081857", "reaction_10083824", "reaction_10081921", "reaction_10082871", "reaction_10081917", "reaction_10083741", "reaction_10083743", "reaction_10081915", "reaction_10083835", "reaction_10081861", "reaction_10077943" ] }, "R-BTA-8963676": { "id": "pathway_10094810", "reactome": "R-BTA-8963676", "name": "Intestinal absorption", "reactions": [ "reaction_10086350" ] }, "R-BTA-1500931": { "id": "pathway_10093622", "reactome": "R-BTA-1500931", "name": "Cell-Cell communication", "reactions": [ "reaction_10048352", "reaction_10049883", "reaction_10049312", "reaction_10048065", "reaction_10047292", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10049304", "reaction_10049891", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-73927": { "id": "pathway_10092758", "reactome": "R-BTA-73927", "name": "Depurination", "reactions": [ "reaction_10091566", "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10091211", "reaction_10036798", "reaction_10091233", "reaction_10091240", "reaction_10036805" ] }, "R-BTA-375281": { "id": "pathway_10093624", "reactome": "R-BTA-375281", "name": "Hormone ligand-binding receptors", "reactions": [ "reaction_10047362", "reaction_10047354", "reaction_10047334" ] }, "R-BTA-163765": { "id": "pathway_10092992", "reactome": "R-BTA-163765", "name": "ChREBP activates metabolic gene expression", "reactions": [ "reaction_10038942" ] }, "R-BTA-9006934": { "id": "pathway_10092646", "reactome": "R-BTA-9006934", "name": "Signaling by Receptor Tyrosine Kinases", "reactions": [ "reaction_10090994", "reaction_10072979", "reaction_10040286", "reaction_10073147", "reaction_10057327", "reaction_10040393", "reaction_10040769", "reaction_10071504", "reaction_10072993", "reaction_10041917", "reaction_10040229", "reaction_10040744", "reaction_10040451", "reaction_10040779", "reaction_10057139", "reaction_10041463", "reaction_10040462", "reaction_10075063", "reaction_10057862", "reaction_10039736", "reaction_10073077", "reaction_10073234", "reaction_10057188", "reaction_10044470", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10039581", "reaction_10053082", "reaction_10057252", "reaction_10084849", "reaction_10090949", "reaction_10070676", "reaction_10039697", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10056781", "reaction_10072999", "reaction_10087373", "reaction_10086415", "reaction_10073102", "reaction_10073001", "reaction_10040447", "reaction_10073031", "reaction_10040277", "reaction_10090675", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10040421", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043488", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10061492", "reaction_10057184", "reaction_10040331", "reaction_10075065", "reaction_10090722", "reaction_10057236", "reaction_10039272", "reaction_10072946", "reaction_10073326", "reaction_10040489", "reaction_10057191", "reaction_10072939", "reaction_10073108", "reaction_10040289", "reaction_10040258", "reaction_10057286", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10041869", "reaction_10091751", "reaction_10039601", "reaction_10073225", "reaction_10040432", "reaction_10035536", "reaction_10039270", "reaction_10057314", "reaction_10071508", "reaction_10073122", "reaction_10040326", "reaction_10058478", "reaction_10040696", "reaction_10070651", "reaction_10070645", "reaction_10057262", "reaction_10073133", "reaction_10057735", "reaction_10057700", "reaction_10057695", "reaction_10057854", "reaction_10073011", "reaction_10039690", "reaction_10073044", "reaction_10058474", "reaction_10065227", "reaction_10073228", "reaction_10072909", "reaction_10044465", "reaction_10090954", "reaction_10057704", "reaction_10074879", "reaction_10087370", "reaction_10080870", "reaction_10040773", "reaction_10073328", "reaction_10083477", "reaction_10084080", "reaction_10061458", "reaction_10040458", "reaction_10041950", "reaction_10083483", "reaction_10073071", "reaction_10040453", "reaction_10043832", "reaction_10040369", "reaction_10057337", "reaction_10057857", "reaction_10073041", "reaction_10040782", "reaction_10041453", "reaction_10040495", "reaction_10044472", "reaction_10057740", "reaction_10040317", "reaction_10035527", "reaction_10041649", "reaction_10073222", "reaction_10072929", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10057151", "reaction_10057872", "reaction_10057175", "reaction_10070628", "reaction_10046660", "reaction_10072976", "reaction_10041851", "reaction_10071506", "reaction_10046677", "reaction_10090727", "reaction_10073199", "reaction_10077601", "reaction_10046666", "reaction_10090971", "reaction_10070594", "reaction_10040386", "reaction_10073004", "reaction_10057177", "reaction_10077605", "reaction_10040303", "reaction_10038450", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10057744", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10036607", "reaction_10084067", "reaction_10073237", "reaction_10057867", "reaction_10073246", "reaction_10040720", "reaction_10058480", "reaction_10039592", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10057719", "reaction_10075097", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10040310", "reaction_10073215", "reaction_10057692", "reaction_10057845", "reaction_10073014", "reaction_10043315", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10040299", "reaction_10061480", "reaction_10057850", "reaction_10040323", "reaction_10090666", "reaction_10072920", "reaction_10070589", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10040570", "reaction_10036570", "reaction_10069535", "reaction_10057284", "reaction_10073242", "reaction_10087367", "reaction_10041657", "reaction_10073166", "reaction_10040684", "reaction_10083935", "reaction_10070615", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10057264", "reaction_10057298", "reaction_10091689", "reaction_10040704", "reaction_10057742", "reaction_10035507", "reaction_10073152", "reaction_10073140", "reaction_10057712", "reaction_10070657", "reaction_10072931", "reaction_10040460", "reaction_10036590", "reaction_10057166", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10073097", "reaction_10057272", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10039711", "reaction_10036616", "reaction_10057302" ] }, "R-BTA-2299718": { "id": "pathway_10094266", "reactome": "R-BTA-2299718", "name": "Condensation of Prophase Chromosomes", "reactions": [ "reaction_10065201", "reaction_10065563", "reaction_10065177", "reaction_10064904" ] }, "R-BTA-9006927": { "id": "pathway_10094726", "reactome": "R-BTA-9006927", "name": "Signaling by Non-Receptor Tyrosine Kinases", "reactions": [ "reaction_10083646", "reaction_10083695", "reaction_10083697", "reaction_10083487", "reaction_10083707", "reaction_10083676", "reaction_10083726", "reaction_10083672", "reaction_10083581", "reaction_10083729", "reaction_10083638", "reaction_10083652", "reaction_10083656", "reaction_10084466", "reaction_10083558", "reaction_10083588", "reaction_10083632", "reaction_10083664", "reaction_10083477", "reaction_10083690", "reaction_10083629", "reaction_10083565", "reaction_10083684", "reaction_10083483", "reaction_10083622" ] }, "R-BTA-5685942": { "id": "pathway_10094592", "reactome": "R-BTA-5685942", "name": "HDR through Homologous Recombination (HRR)", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075151" ] }, "R-BTA-205043": { "id": "pathway_10093392", "reactome": "R-BTA-205043", "name": "NRIF signals cell death from the nucleus", "reactions": [ "reaction_10043744", "reaction_10043739", "reaction_10043778" ] }, "R-BTA-5654693": { "id": "pathway_10094522", "reactome": "R-BTA-5654693", "name": "FRS-mediated FGFR1 signaling", "reactions": [ "reaction_10072957", "reaction_10073083", "reaction_10073090", "reaction_10073097", "reaction_10073108", "reaction_10087373", "reaction_10073106", "reaction_10073113" ] }, "R-BTA-2161541": { "id": "pathway_10094252", "reactome": "R-BTA-2161541", "name": "Abacavir metabolism", "reactions": [ "reaction_10064584" ] }, "R-BTA-446728": { "id": "pathway_10093690", "reactome": "R-BTA-446728", "name": "Cell junction organization", "reactions": [ "reaction_10048352", "reaction_10049883", "reaction_10049312", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10049304", "reaction_10049891", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-629597": { "id": "pathway_10093840", "reactome": "R-BTA-629597", "name": "Highly calcium permeable nicotinic acetylcholine receptors", "reactions": [ "reaction_10051498", "reaction_10051525" ] }, "R-BTA-5250941": { "id": "pathway_10093714", "reactome": "R-BTA-5250941", "name": "Negative epigenetic regulation of rRNA expression", "reactions": [ "reaction_10048682", "reaction_10048717", "reaction_10048720" ] }, "R-BTA-975110": { "id": "pathway_10093898", "reactome": "R-BTA-975110", "name": "TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling", "reactions": [ "reaction_10053048", "reaction_10053046" ] }, "R-BTA-110313": { "id": "pathway_10092762", "reactome": "R-BTA-110313", "name": "Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template", "reactions": [ "reaction_10072883", "reaction_10036886", "reaction_10073302", "reaction_10073279", "reaction_10036844", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036853", "reaction_10036879", "reaction_10072876", "reaction_10036869" ] }, "R-BTA-8983432": { "id": "pathway_10094868", "reactome": "R-BTA-8983432", "name": "Interleukin-15 signaling", "reactions": [ "reaction_10089291", "reaction_10089267", "reaction_10089269", "reaction_10089311" ] }, "R-BTA-167060": { "id": "pathway_10093146", "reactome": "R-BTA-167060", "name": "NGF processing", "reactions": [ "reaction_10040489", "reaction_10040495" ] }, "R-BTA-442729": { "id": "pathway_10092794", "reactome": "R-BTA-442729", "name": "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde", "reactions": [ "reaction_10049478", "reaction_10036981" ] }, "R-BTA-198753": { "id": "pathway_10093304", "reactome": "R-BTA-198753", "name": "ERK/MAPK targets", "reactions": [ "reaction_10042826", "reaction_10043488", "reaction_10041950" ] }, "R-BTA-9006931": { "id": "pathway_10093326", "reactome": "R-BTA-9006931", "name": "Signaling by Nuclear Receptors", "reactions": [ "reaction_10090563", "reaction_10091151", "reaction_10090571", "reaction_10090452", "reaction_10071397", "reaction_10071407", "reaction_10090456", "reaction_10042860", "reaction_10091275", "reaction_10072397", "reaction_10091158", "reaction_10090567", "reaction_10091115", "reaction_10089761", "reaction_10090559", "reaction_10091156", "reaction_10072433", "reaction_10071659", "reaction_10072630", "reaction_10076840", "reaction_10091271", "reaction_10072628", "reaction_10072225", "reaction_10090712", "reaction_10071648", "reaction_10071668", "reaction_10091260", "reaction_10071678", "reaction_10044211", "reaction_10086662", "reaction_10071691", "reaction_10091118", "reaction_10092314", "reaction_10091267", "reaction_10090555", "reaction_10071673" ] }, "R-BTA-111931": { "id": "pathway_10092804", "reactome": "R-BTA-111931", "name": "PKA-mediated phosphorylation of CREB", "reactions": [ "reaction_10037004" ] }, "R-BTA-1299316": { "id": "pathway_10094056", "reactome": "R-BTA-1299316", "name": "TWIK-releated acid-sensitive K+ channel (TASK)", "reactions": [ "reaction_10057656" ] }, "R-BTA-9018677": { "id": "pathway_10094912", "reactome": "R-BTA-9018677", "name": "Biosynthesis of DHA-derived SPMs", "reactions": [ "reaction_10090491", "reaction_10090498", "reaction_10090480", "reaction_10090489", "reaction_10090386", "reaction_10090390", "reaction_10090458", "reaction_10090460", "reaction_10090708", "reaction_10090388", "reaction_10090394", "reaction_10090384", "reaction_10090392", "reaction_10090464", "reaction_10090462" ] }, "R-BTA-71240": { "id": "pathway_10092542", "reactome": "R-BTA-71240", "name": "Tryptophan catabolism", "reactions": [ "reaction_10052027", "reaction_10052030", "reaction_10033988", "reaction_10085381", "reaction_10033979", "reaction_10052043", "reaction_10041894", "reaction_10033969" ] }, "R-BTA-8951671": { "id": "pathway_10094842", "reactome": "R-BTA-8951671", "name": "RUNX3 regulates YAP1-mediated transcription", "reactions": [ "reaction_10087862" ] }, "R-BTA-1650814": { "id": "pathway_10094128", "reactome": "R-BTA-1650814", "name": "Collagen biosynthesis and modifying enzymes", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10062071", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10087626", "reaction_10060191", "reaction_10060187", "reaction_10062377", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10064337", "reaction_10061787", "reaction_10087567", "reaction_10087569", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10087579" ] }, "R-BTA-9013406": { "id": "pathway_10094900", "reactome": "R-BTA-9013406", "name": "RHOQ GTPase cycle", "reactions": [ "reaction_10090246", "reaction_10090369", "reaction_10090266" ] }, "R-BTA-9025106": { "id": "pathway_10094926", "reactome": "R-BTA-9025106", "name": "Biosynthesis of DPAn-6 SPMs", "reactions": [ "reaction_10090466", "reaction_10090468" ] }, "R-BTA-390696": { "id": "pathway_10093606", "reactome": "R-BTA-390696", "name": "Adrenoceptors", "reactions": [ "reaction_10047206", "reaction_10047212", "reaction_10090960", "reaction_10090968", "reaction_10090925", "reaction_10090964" ] }, "R-BTA-2142770": { "id": "pathway_10094250", "reactome": "R-BTA-2142770", "name": "Synthesis of 15-eicosatetraenoic acid derivatives", "reactions": [ "reaction_10064546", "reaction_10064578" ] }, "R-BTA-2142700": { "id": "pathway_10094238", "reactome": "R-BTA-2142700", "name": "Synthesis of Lipoxins (LX)", "reactions": [ "reaction_10064500", "reaction_10064491" ] }, "R-BTA-176974": { "id": "pathway_10093128", "reactome": "R-BTA-176974", "name": "Unwinding of DNA", "reactions": [ "reaction_10040183" ] }, "R-BTA-6804116": { "id": "pathway_10094854", "reactome": "R-BTA-6804116", "name": "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest", "reactions": [ "reaction_10088546", "reaction_10088542", "reaction_10088534" ] }, "R-BTA-5663213": { "id": "pathway_10094204", "reactome": "R-BTA-5663213", "name": "RHO GTPases Activate WASPs and WAVEs", "reactions": [ "reaction_10063374" ] }, "R-BTA-181431": { "id": "pathway_10093844", "reactome": "R-BTA-181431", "name": "Acetylcholine binding and downstream events", "reactions": [ "reaction_10051498", "reaction_10051523", "reaction_10051521", "reaction_10051525" ] }, "R-BTA-2046106": { "id": "pathway_10094220", "reactome": "R-BTA-2046106", "name": "alpha-linolenic acid (ALA) metabolism", "reactions": [ "reaction_10063440", "reaction_10063430", "reaction_10063456", "reaction_10063570", "reaction_10063428", "reaction_10063437", "reaction_10063420", "reaction_10063425", "reaction_10063573" ] }, "R-BTA-6807070": { "id": "pathway_10094830", "reactome": "R-BTA-6807070", "name": "PTEN Regulation", "reactions": [ "reaction_10087531" ] }, "R-BTA-68827": { "id": "pathway_10092404", "reactome": "R-BTA-68827", "name": "CDT1 association with the CDC6:ORC:origin complex", "reactions": [ "reaction_10033412" ] }, "R-BTA-3000178": { "id": "pathway_10094282", "reactome": "R-BTA-3000178", "name": "ECM proteoglycans", "reactions": [ "reaction_10065691", "reaction_10065300" ] }, "R-BTA-5205685": { "id": "pathway_10094418", "reactome": "R-BTA-5205685", "name": "PINK1-PRKN Mediated Mitophagy", "reactions": [ "reaction_10070259", "reaction_10070218", "reaction_10070261", "reaction_10070265" ] }, "R-BTA-6799198": { "id": "pathway_10094672", "reactome": "R-BTA-6799198", "name": "Complex I biogenesis", "reactions": [ "reaction_10080515", "reaction_10080519", "reaction_10080517", "reaction_10080521" ] }, "R-BTA-2160916": { "id": "pathway_10094230", "reactome": "R-BTA-2160916", "name": "Hyaluronan uptake and degradation", "reactions": [ "reaction_10064597", "reaction_10064595", "reaction_10064355", "reaction_10064593", "reaction_10064393", "reaction_10091291", "reaction_10064391" ] }, "R-BTA-177929": { "id": "pathway_10092740", "reactome": "R-BTA-177929", "name": "Signaling by EGFR", "reactions": [ "reaction_10044472", "reaction_10040286", "reaction_10040317", "reaction_10040393", "reaction_10091705", "reaction_10040289", "reaction_10040299", "reaction_10040229", "reaction_10040258", "reaction_10040451", "reaction_10040323", "reaction_10040462", "reaction_10040432", "reaction_10040310", "reaction_10044470", "reaction_10040326", "reaction_10040386", "reaction_10040328", "reaction_10040303", "reaction_10044465", "reaction_10040447", "reaction_10040277", "reaction_10040460", "reaction_10040421", "reaction_10040254", "reaction_10040458", "reaction_10040267", "reaction_10040453", "reaction_10040369", "reaction_10036616", "reaction_10040331" ] }, "R-BTA-447115": { "id": "pathway_10093784", "reactome": "R-BTA-447115", "name": "Interleukin-12 family signaling", "reactions": [ "reaction_10049970", "reaction_10087663", "reaction_10087787", "reaction_10087671", "reaction_10087789", "reaction_10087766", "reaction_10049928", "reaction_10089321", "reaction_10089333", "reaction_10087650", "reaction_10087732", "reaction_10089329", "reaction_10089331", "reaction_10087780", "reaction_10087795", "reaction_10088498", "reaction_10087793", "reaction_10049946", "reaction_10087697", "reaction_10087783", "reaction_10087763", "reaction_10087726", "reaction_10087774", "reaction_10088519" ] }, "R-BTA-163359": { "id": "pathway_10092978", "reactome": "R-BTA-163359", "name": "Glucagon signaling in metabolic regulation", "reactions": [ "reaction_10038918" ] }, "R-BTA-5620922": { "id": "pathway_10094494", "reactome": "R-BTA-5620922", "name": "BBSome-mediated cargo-targeting to cilium", "reactions": [ "reaction_10072435", "reaction_10072453", "reaction_10072475" ] }, "R-BTA-73893": { "id": "pathway_10092764", "reactome": "R-BTA-73893", "name": "DNA Damage Bypass", "reactions": [ "reaction_10072883", "reaction_10036886", "reaction_10073302", "reaction_10073279", "reaction_10036844", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036853", "reaction_10036879", "reaction_10072876", "reaction_10036869" ] }, "R-BTA-392451": { "id": "pathway_10093358", "reactome": "R-BTA-392451", "name": "G beta:gamma signalling through PI3Kgamma", "reactions": [ "reaction_10047498", "reaction_10043315" ] }, "R-BTA-9013694": { "id": "pathway_10094976", "reactome": "R-BTA-9013694", "name": "Signaling by NOTCH4", "reactions": [ "reaction_10090834" ] }, "R-BTA-8878171": { "id": "pathway_10094814", "reactome": "R-BTA-8878171", "name": "Transcriptional regulation by RUNX1", "reactions": [ "reaction_10086534", "reaction_10088887", "reaction_10086518", "reaction_10086458", "reaction_10086509", "reaction_10086525", "reaction_10086493", "reaction_10086502", "reaction_10088872", "reaction_10088876", "reaction_10086638", "reaction_10086541" ] }, "R-BTA-1474290": { "id": "pathway_10094088", "reactome": "R-BTA-1474290", "name": "Collagen formation", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10065929", "reaction_10062071", "reaction_10058705", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10064953", "reaction_10087626", "reaction_10060191", "reaction_10060187", "reaction_10062377", "reaction_10064959", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10064337", "reaction_10061787", "reaction_10087567", "reaction_10087569", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10087579" ] }, "R-BTA-351202": { "id": "pathway_10092506", "reactome": "R-BTA-351202", "name": "Metabolism of polyamines", "reactions": [ "reaction_10044794", "reaction_10044835", "reaction_10044784", "reaction_10044851", "reaction_10033778", "reaction_10044801", "reaction_10044844", "reaction_10044837", "reaction_10044776" ] }, "R-BTA-5652227": { "id": "pathway_10094500", "reactome": "R-BTA-5652227", "name": "Fructose biosynthesis", "reactions": [ "reaction_10072825" ] }, "R-BTA-163754": { "id": "pathway_10092990", "reactome": "R-BTA-163754", "name": "Insulin effects increased synthesis of Xylulose-5-Phosphate", "reactions": [] }, "R-BTA-9013106": { "id": "pathway_10094888", "reactome": "R-BTA-9013106", "name": "RHOC GTPase cycle", "reactions": [ "reaction_10089937", "reaction_10092364", "reaction_10089952", "reaction_10089947" ] }, "R-BTA-6803157": { "id": "pathway_10093982", "reactome": "R-BTA-6803157", "name": "Antimicrobial peptides", "reactions": [ "reaction_10082008", "reaction_10058492", "reaction_10081559", "reaction_10081404", "reaction_10078759", "reaction_10083106", "reaction_10081385", "reaction_10081406", "reaction_10081410", "reaction_10082967", "reaction_10084683", "reaction_10058486", "reaction_10080844", "reaction_10084706", "reaction_10081943", "reaction_10082183", "reaction_10087601", "reaction_10080831", "reaction_10061657", "reaction_10084686", "reaction_10056539", "reaction_10058456", "reaction_10082977", "reaction_10081432", "reaction_10083100", "reaction_10082004", "reaction_10081397", "reaction_10080842", "reaction_10070906", "reaction_10056416", "reaction_10058388", "reaction_10082012" ] }, "R-BTA-1296025": { "id": "pathway_10094024", "reactome": "R-BTA-1296025", "name": "ATP sensitive Potassium channels", "reactions": [ "reaction_10057350" ] }, "R-BTA-8978934": { "id": "pathway_10093586", "reactome": "R-BTA-8978934", "name": "Metabolism of cofactors", "reactions": [ "reaction_10058511", "reaction_10058785", "reaction_10064591", "reaction_10058524", "reaction_10058514", "reaction_10046968" ] }, "R-BTA-1660499": { "id": "pathway_10094142", "reactome": "R-BTA-1660499", "name": "Synthesis of PIPs at the plasma membrane", "reactions": [ "reaction_10060550", "reaction_10082147", "reaction_10060473", "reaction_10085697", "reaction_10082136", "reaction_10060572", "reaction_10060514", "reaction_10082152", "reaction_10085784", "reaction_10060535", "reaction_10060569", "reaction_10085780", "reaction_10060600", "reaction_10060595", "reaction_10060590", "reaction_10060579", "reaction_10060556", "reaction_10085775", "reaction_10060448", "reaction_10060429", "reaction_10060461", "reaction_10082155" ] }, "R-BTA-9634638": { "id": "pathway_10094996", "reactome": "R-BTA-9634638", "name": "Estrogen-dependent nuclear events downstream of ESR-membrane signaling", "reactions": [ "reaction_10091267", "reaction_10091118" ] }, "R-BTA-75815": { "id": "pathway_10092664", "reactome": "R-BTA-75815", "name": "Ubiquitin-dependent degradation of Cyclin D", "reactions": [ "reaction_10035745", "reaction_10035747" ] }, "R-BTA-1295596": { "id": "pathway_10093904", "reactome": "R-BTA-1295596", "name": "Spry regulation of FGF signaling", "reactions": [ "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-74259": { "id": "pathway_10092636", "reactome": "R-BTA-74259", "name": "Purine catabolism", "reactions": [ "reaction_10035464", "reaction_10065359", "reaction_10065763", "reaction_10035455", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10065381", "reaction_10088571", "reaction_10036231", "reaction_10036207", "reaction_10065378", "reaction_10065362", "reaction_10065371", "reaction_10036256", "reaction_10065760", "reaction_10035453", "reaction_10065383", "reaction_10036238", "reaction_10065386" ] }, "R-BTA-5633007": { "id": "pathway_10092432", "reactome": "R-BTA-5633007", "name": "Regulation of TP53 Activity", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10082931", "reaction_10066870", "reaction_10081877", "reaction_10078731", "reaction_10033535", "reaction_10080730", "reaction_10081629", "reaction_10083072", "reaction_10082923", "reaction_10081541", "reaction_10066764", "reaction_10081522", "reaction_10080797", "reaction_10066704", "reaction_10082934", "reaction_10066684", "reaction_10072550", "reaction_10081470", "reaction_10081563", "reaction_10081602", "reaction_10066724", "reaction_10066670", "reaction_10066737", "reaction_10083092", "reaction_10086155", "reaction_10076341", "reaction_10081530", "reaction_10083077", "reaction_10078408", "reaction_10078720", "reaction_10081595", "reaction_10066712", "reaction_10081889", "reaction_10081622", "reaction_10080811", "reaction_10081561" ] }, "R-BTA-446343": { "id": "pathway_10093780", "reactome": "R-BTA-446343", "name": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions", "reactions": [ "reaction_10049883" ] }, "R-BTA-1480926": { "id": "pathway_10094004", "reactome": "R-BTA-1480926", "name": "O2/CO2 exchange in erythrocytes", "reactions": [ "reaction_10058790", "reaction_10057007", "reaction_10081968", "reaction_10058792", "reaction_10057062", "reaction_10057070" ] }, "R-BTA-5669034": { "id": "pathway_10094562", "reactome": "R-BTA-5669034", "name": "TNFs bind their physiological receptors", "reactions": [ "reaction_10073765", "reaction_10076237", "reaction_10076165", "reaction_10074280", "reaction_10074266", "reaction_10074340" ] }, "R-BTA-927802": { "id": "pathway_10093894", "reactome": "R-BTA-927802", "name": "Nonsense-Mediated Decay (NMD)", "reactions": [ "reaction_10052963", "reaction_10053044" ] }, "R-BTA-8964616": { "id": "pathway_10094860", "reactome": "R-BTA-8964616", "name": "G beta:gamma signalling through CDC42", "reactions": [ "reaction_10088962" ] }, "R-BTA-264642": { "id": "pathway_10093454", "reactome": "R-BTA-264642", "name": "Acetylcholine Neurotransmitter Release Cycle", "reactions": [ "reaction_10044540", "reaction_10049090" ] }, "R-BTA-77111": { "id": "pathway_10092608", "reactome": "R-BTA-77111", "name": "Synthesis of Ketone Bodies", "reactions": [ "reaction_10035363", "reaction_10035372" ] }, "R-BTA-4839726": { "id": "pathway_10093978", "reactome": "R-BTA-4839726", "name": "Chromatin organization", "reactions": [ "reaction_10072790", "reaction_10069838", "reaction_10070757", "reaction_10073406", "reaction_10073416", "reaction_10069939", "reaction_10070377", "reaction_10069937", "reaction_10070516", "reaction_10072725", "reaction_10073382", "reaction_10067596", "reaction_10072655", "reaction_10070392", "reaction_10070896", "reaction_10069796", "reaction_10056383", "reaction_10073384", "reaction_10070409", "reaction_10072755", "reaction_10068569", "reaction_10073396", "reaction_10072788", "reaction_10073380", "reaction_10069719", "reaction_10069754", "reaction_10071886", "reaction_10069769", "reaction_10069747", "reaction_10073394", "reaction_10068725", "reaction_10072752", "reaction_10073404", "reaction_10066651", "reaction_10069740", "reaction_10072750", "reaction_10072778", "reaction_10066966", "reaction_10070520", "reaction_10070962", "reaction_10073402", "reaction_10069846", "reaction_10070282", "reaction_10073400", "reaction_10068699", "reaction_10072823", "reaction_10085017", "reaction_10072813", "reaction_10091745", "reaction_10068844" ] }, "R-BTA-6804757": { "id": "pathway_10094332", "reactome": "R-BTA-6804757", "name": "Regulation of TP53 Degradation", "reactions": [ "reaction_10066684", "reaction_10081541", "reaction_10078408" ] }, "R-BTA-9018679": { "id": "pathway_10094908", "reactome": "R-BTA-9018679", "name": "Biosynthesis of EPA-derived SPMs", "reactions": [ "reaction_10090374", "reaction_10090396", "reaction_10090440", "reaction_10090382", "reaction_10090379", "reaction_10090377" ] }, "R-BTA-168188": { "id": "pathway_10093040", "reactome": "R-BTA-168188", "name": "Toll Like Receptor TLR6:TLR2 Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1300642": { "id": "pathway_10094308", "reactome": "R-BTA-1300642", "name": "Sperm Motility And Taxes", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10065866" ] }, "R-BTA-112313": { "id": "pathway_10092496", "reactome": "R-BTA-112313", "name": "Neurotransmitter uptake and metabolism In glial cells", "reactions": [ "reaction_10033746", "reaction_10044086" ] }, "R-BTA-381070": { "id": "pathway_10093546", "reactome": "R-BTA-381070", "name": "IRE1alpha activates chaperones", "reactions": [ "reaction_10046602", "reaction_10046604" ] }, "R-BTA-180024": { "id": "pathway_10092808", "reactome": "R-BTA-180024", "name": "DARPP-32 events", "reactions": [ "reaction_10037037" ] }, "R-BTA-5654710": { "id": "pathway_10094546", "reactome": "R-BTA-5654710", "name": "PI-3K cascade:FGFR3", "reactions": [ "reaction_10073234" ] }, "R-BTA-211945": { "id": "pathway_10092560", "reactome": "R-BTA-211945", "name": "Phase I - Functionalization of compounds", "reactions": [ "reaction_10044477", "reaction_10044533", "reaction_10077496", "reaction_10086550", "reaction_10041177", "reaction_10075404", "reaction_10076375", "reaction_10043971", "reaction_10041412", "reaction_10044235", "reaction_10041386", "reaction_10035958", "reaction_10044182", "reaction_10044255", "reaction_10037751", "reaction_10086543", "reaction_10034231", "reaction_10034206", "reaction_10044242", "reaction_10044280", "reaction_10041415", "reaction_10044250", "reaction_10044223", "reaction_10044275", "reaction_10044204", "reaction_10035977", "reaction_10077734", "reaction_10041195", "reaction_10035878", "reaction_10044216", "reaction_10076884", "reaction_10044524", "reaction_10044225", "reaction_10044265", "reaction_10035911", "reaction_10037748", "reaction_10041397", "reaction_10044167", "reaction_10038000", "reaction_10071909", "reaction_10044247", "reaction_10034175", "reaction_10086557", "reaction_10034215", "reaction_10044195", "reaction_10077751", "reaction_10035865", "reaction_10044218", "reaction_10043964", "reaction_10041393", "reaction_10041193", "reaction_10044151", "reaction_10044270", "reaction_10076144", "reaction_10041277", "reaction_10086469", "reaction_10044211", "reaction_10044480", "reaction_10044158", "reaction_10076475", "reaction_10041217", "reaction_10041206", "reaction_10076856", "reaction_10044260", "reaction_10044232", "reaction_10044293", "reaction_10076863", "reaction_10035861", "reaction_10050160", "reaction_10041500" ] }, "R-BTA-69236": { "id": "pathway_10093138", "reactome": "R-BTA-69236", "name": "G1 Phase", "reactions": [ "reaction_10056602", "reaction_10056616", "reaction_10087394", "reaction_10087487", "reaction_10057821", "reaction_10057816", "reaction_10087385", "reaction_10040355", "reaction_10087503" ] }, "R-BTA-192456": { "id": "pathway_10093244", "reactome": "R-BTA-192456", "name": "Digestion of dietary lipid", "reactions": [ "reaction_10054375", "reaction_10041241", "reaction_10088973", "reaction_10041239" ] }, "R-BTA-202131": { "id": "pathway_10094628", "reactome": "R-BTA-202131", "name": "Metabolism of nitric oxide: NOS3 activation and regulation", "reactions": [ "reaction_10076274" ] }, "R-BTA-2142845": { "id": "pathway_10094228", "reactome": "R-BTA-2142845", "name": "Hyaluronan metabolism", "reactions": [ "reaction_10064597", "reaction_10064595", "reaction_10064355", "reaction_10064593", "reaction_10064393", "reaction_10091291", "reaction_10064353", "reaction_10064391" ] }, "R-BTA-204174": { "id": "pathway_10094880", "reactome": "R-BTA-204174", "name": "Regulation of pyruvate dehydrogenase (PDH) complex", "reactions": [ "reaction_10089721", "reaction_10089728" ] }, "R-BTA-453274": { "id": "pathway_10093090", "reactome": "R-BTA-453274", "name": "Mitotic G2-G2/M phases", "reactions": [ "reaction_10039612", "reaction_10084043", "reaction_10084051", "reaction_10039614", "reaction_10084102", "reaction_10065938", "reaction_10066489", "reaction_10084090", "reaction_10084216", "reaction_10084214", "reaction_10084047", "reaction_10084206", "reaction_10084096", "reaction_10066487", "reaction_10084028" ] }, "R-BTA-3238698": { "id": "pathway_10094342", "reactome": "R-BTA-3238698", "name": "WNT ligand biogenesis and trafficking", "reactions": [ "reaction_10067128", "reaction_10067124", "reaction_10067202", "reaction_10067200", "reaction_10068839", "reaction_10068837", "reaction_10066994", "reaction_10067204" ] }, "R-BTA-8935690": { "id": "pathway_10093162", "reactome": "R-BTA-8935690", "name": "Digestion", "reactions": [ "reaction_10041239", "reaction_10086435", "reaction_10040866", "reaction_10041241", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10086248", "reaction_10088973", "reaction_10073378", "reaction_10040608", "reaction_10054375", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-5365859": { "id": "pathway_10093438", "reactome": "R-BTA-5365859", "name": "RA biosynthesis pathway", "reactions": [ "reaction_10071659", "reaction_10071648", "reaction_10071668", "reaction_10071678", "reaction_10072397", "reaction_10044211", "reaction_10071691", "reaction_10076840", "reaction_10072433", "reaction_10072225", "reaction_10071673" ] }, "R-BTA-5694530": { "id": "pathway_10094632", "reactome": "R-BTA-5694530", "name": "Cargo concentration in the ER", "reactions": [ "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10076696", "reaction_10076586", "reaction_10076706" ] }, "R-BTA-9008059": { "id": "pathway_10094732", "reactome": "R-BTA-9008059", "name": "Interleukin-37 signaling", "reactions": [ "reaction_10089615", "reaction_10089819", "reaction_10089621", "reaction_10089625", "reaction_10089812", "reaction_10083537", "reaction_10089843" ] }, "R-BTA-1236978": { "id": "pathway_10093992", "reactome": "R-BTA-1236978", "name": "Cross-presentation of soluble exogenous antigens (endosomes)", "reactions": [ "reaction_10056912", "reaction_10056835", "reaction_10056805" ] }, "R-BTA-2990846": { "id": "pathway_10094326", "reactome": "R-BTA-2990846", "name": "SUMOylation", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-8939242": { "id": "pathway_10094818", "reactome": "R-BTA-8939242", "name": "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes", "reactions": [ "reaction_10086638" ] }, "R-BTA-75067": { "id": "pathway_10092720", "reactome": "R-BTA-75067", "name": "Processing of Capped Intronless Pre-mRNA", "reactions": [ "reaction_10036076", "reaction_10036915", "reaction_10036917", "reaction_10036052", "reaction_10036080" ] }, "R-BTA-2032785": { "id": "pathway_10094214", "reactome": "R-BTA-2032785", "name": "YAP1- and WWTR1 (TAZ)-stimulated gene expression", "reactions": [ "reaction_10085761", "reaction_10063390", "reaction_10063400" ] }, "R-BTA-174403": { "id": "pathway_10093114", "reactome": "R-BTA-174403", "name": "Glutathione synthesis and recycling", "reactions": [ "reaction_10039865", "reaction_10057079", "reaction_10077658", "reaction_10087515" ] }, "R-BTA-400206": { "id": "pathway_10093652", "reactome": "R-BTA-400206", "name": "Regulation of lipid metabolism by PPARalpha", "reactions": [ "reaction_10047807" ] }, "R-BTA-217271": { "id": "pathway_10093450", "reactome": "R-BTA-217271", "name": "FMO oxidises nucleophiles", "reactions": [ "reaction_10044524", "reaction_10044533" ] }, "R-BTA-9614085": { "id": "pathway_10094984", "reactome": "R-BTA-9614085", "name": "FOXO-mediated transcription", "reactions": [ "reaction_10091049", "reaction_10091017", "reaction_10091033", "reaction_10091023", "reaction_10091029", "reaction_10091096", "reaction_10091184", "reaction_10091089" ] }, "R-BTA-209560": { "id": "pathway_10093402", "reactome": "R-BTA-209560", "name": "NF-kB is activated and signals survival", "reactions": [ "reaction_10043877" ] }, "R-BTA-5689877": { "id": "pathway_10094612", "reactome": "R-BTA-5689877", "name": "Josephin domain DUBs", "reactions": [ "reaction_10075397", "reaction_10075374" ] }, "R-BTA-390666": { "id": "pathway_10093618", "reactome": "R-BTA-390666", "name": "Serotonin receptors", "reactions": [ "reaction_10091929", "reaction_10047238", "reaction_10047236", "reaction_10047256" ] }, "R-BTA-199977": { "id": "pathway_10093374", "reactome": "R-BTA-199977", "name": "ER to Golgi Anterograde Transport", "reactions": [ "reaction_10083380", "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10076708", "reaction_10076610", "reaction_10076696", "reaction_10076778", "reaction_10076635", "reaction_10076736", "reaction_10082038", "reaction_10076586", "reaction_10076706", "reaction_10082026", "reaction_10082045", "reaction_10083377", "reaction_10076584", "reaction_10076698" ] }, "R-BTA-1852241": { "id": "pathway_10094486", "reactome": "R-BTA-1852241", "name": "Organelle biogenesis and maintenance", "reactions": [ "reaction_10075350", "reaction_10075362", "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072271", "reaction_10072489", "reaction_10072453", "reaction_10087635", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-390522": { "id": "pathway_10093602", "reactome": "R-BTA-390522", "name": "Striated Muscle Contraction", "reactions": [ "reaction_10047200", "reaction_10047198", "reaction_10047186", "reaction_10047196" ] }, "R-BTA-156902": { "id": "pathway_10092908", "reactome": "R-BTA-156902", "name": "Peptide chain elongation", "reactions": [ "reaction_10038107" ] }, "R-BTA-191273": { "id": "pathway_10093218", "reactome": "R-BTA-191273", "name": "Cholesterol biosynthesis", "reactions": [ "reaction_10041486", "reaction_10040904", "reaction_10040913", "reaction_10040881", "reaction_10081990", "reaction_10041484", "reaction_10040933", "reaction_10041728", "reaction_10081988", "reaction_10040892", "reaction_10081986", "reaction_10041493", "reaction_10088019", "reaction_10041671", "reaction_10040895", "reaction_10040924", "reaction_10041477", "reaction_10041502", "reaction_10083496", "reaction_10040922", "reaction_10041664", "reaction_10041500" ] }, "R-BTA-2129379": { "id": "pathway_10094232", "reactome": "R-BTA-2129379", "name": "Molecules associated with elastic fibres", "reactions": [ "reaction_10064435", "reaction_10065336", "reaction_10065435" ] }, "R-BTA-9027276": { "id": "pathway_10094884", "reactome": "R-BTA-9027276", "name": "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)", "reactions": [ "reaction_10090501", "reaction_10090428", "reaction_10089841" ] }, "R-BTA-1482788": { "id": "pathway_10094092", "reactome": "R-BTA-1482788", "name": "Acyl chain remodelling of PC", "reactions": [ "reaction_10058990", "reaction_10059858", "reaction_10058970", "reaction_10059856", "reaction_10058829", "reaction_10085826", "reaction_10058996", "reaction_10058809" ] }, "R-BTA-9707587": { "id": "pathway_10095042", "reactome": "R-BTA-9707587", "name": "Regulation of HMOX1 expression and activity", "reactions": [ "reaction_10092289", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10092239" ] }, "R-BTA-196299": { "id": "pathway_10093274", "reactome": "R-BTA-196299", "name": "Beta-catenin phosphorylation cascade", "reactions": [ "reaction_10041647", "reaction_10041629", "reaction_10041637", "reaction_10041640" ] }, "R-BTA-5617833": { "id": "pathway_10094484", "reactome": "R-BTA-5617833", "name": "Cilium Assembly", "reactions": [ "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072271", "reaction_10072489", "reaction_10072453", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-1475029": { "id": "pathway_10094090", "reactome": "R-BTA-1475029", "name": "Reversible hydration of carbon dioxide", "reactions": [ "reaction_10058722", "reaction_10058772", "reaction_10058755", "reaction_10058751", "reaction_10058774", "reaction_10058753" ] }, "R-BTA-140534": { "id": "pathway_10092616", "reactome": "R-BTA-140534", "name": "Caspase activation via Death Receptors in the presence of ligand", "reactions": [ "reaction_10068046", "reaction_10035396", "reaction_10068042", "reaction_10037991", "reaction_10037985", "reaction_10067895", "reaction_10067891" ] }, "R-BTA-912526": { "id": "pathway_10093822", "reactome": "R-BTA-912526", "name": "Interleukin receptor SHC signaling", "reactions": [ "reaction_10052343", "reaction_10050623", "reaction_10050619", "reaction_10052254", "reaction_10052337" ] }, "R-BTA-156590": { "id": "pathway_10093116", "reactome": "R-BTA-156590", "name": "Glutathione conjugation", "reactions": [ "reaction_10057079", "reaction_10039865", "reaction_10040021", "reaction_10067425", "reaction_10087515", "reaction_10076133", "reaction_10040030", "reaction_10077658" ] }, "R-BTA-211859": { "id": "pathway_10092562", "reactome": "R-BTA-211859", "name": "Biological oxidations", "reactions": [ "reaction_10071712", "reaction_10039887", "reaction_10038318", "reaction_10071722", "reaction_10038338", "reaction_10044255", "reaction_10035863", "reaction_10040136", "reaction_10044250", "reaction_10076900", "reaction_10038060", "reaction_10035977", "reaction_10076898", "reaction_10040030", "reaction_10071763", "reaction_10035911", "reaction_10071909", "reaction_10040115", "reaction_10034215", "reaction_10038380", "reaction_10087515", "reaction_10038340", "reaction_10039921", "reaction_10038354", "reaction_10086469", "reaction_10041277", "reaction_10044211", "reaction_10044480", "reaction_10038336", "reaction_10040021", "reaction_10044232", "reaction_10076903", "reaction_10041500", "reaction_10071754", "reaction_10044477", "reaction_10071729", "reaction_10038371", "reaction_10041177", "reaction_10071717", "reaction_10043971", "reaction_10077658", "reaction_10039874", "reaction_10044235", "reaction_10041386", "reaction_10044182", "reaction_10086543", "reaction_10038231", "reaction_10034206", "reaction_10044223", "reaction_10041415", "reaction_10044225", "reaction_10038000", "reaction_10039865", "reaction_10039918", "reaction_10040152", "reaction_10044270", "reaction_10041193", "reaction_10067425", "reaction_10041206", "reaction_10076856", "reaction_10044293", "reaction_10050160", "reaction_10040185", "reaction_10077496", "reaction_10075404", "reaction_10041412", "reaction_10037751", "reaction_10034231", "reaction_10040129", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10037748", "reaction_10076884", "reaction_10044265", "reaction_10040157", "reaction_10041397", "reaction_10044167", "reaction_10044247", "reaction_10034175", "reaction_10040112", "reaction_10071924", "reaction_10038382", "reaction_10076799", "reaction_10086557", "reaction_10038238", "reaction_10044195", "reaction_10039930", "reaction_10040107", "reaction_10041393", "reaction_10040098", "reaction_10071715", "reaction_10088617", "reaction_10076475", "reaction_10044158", "reaction_10040117", "reaction_10039916", "reaction_10076785", "reaction_10035861", "reaction_10076863", "reaction_10076133", "reaction_10038316", "reaction_10041195", "reaction_10040147", "reaction_10044533", "reaction_10086550", "reaction_10076375", "reaction_10035958", "reaction_10044242", "reaction_10044204", "reaction_10044275", "reaction_10035878", "reaction_10040131", "reaction_10044216", "reaction_10040122", "reaction_10044524", "reaction_10057079", "reaction_10077751", "reaction_10040120", "reaction_10035865", "reaction_10038320", "reaction_10044218", "reaction_10043964", "reaction_10044151", "reaction_10076144", "reaction_10051570", "reaction_10071727", "reaction_10041217", "reaction_10044260", "reaction_10039923", "reaction_10088580" ] }, "R-BTA-8866654": { "id": "pathway_10094822", "reactome": "R-BTA-8866654", "name": "E3 ubiquitin ligases ubiquitinate target proteins", "reactions": [ "reaction_10086710", "reaction_10086702" ] }, "R-BTA-622323": { "id": "pathway_10093842", "reactome": "R-BTA-622323", "name": "Presynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051498", "reaction_10051525" ] }, "R-BTA-983168": { "id": "pathway_10093944", "reactome": "R-BTA-983168", "name": "Antigen processing: Ubiquitination & Proteasome degradation", "reactions": [ "reaction_10055491", "reaction_10055448", "reaction_10055431", "reaction_10055451", "reaction_10055453" ] }, "R-BTA-5632684": { "id": "pathway_10094478", "reactome": "R-BTA-5632684", "name": "Hedgehog 'on' state", "reactions": [ "reaction_10072606", "reaction_10072720", "reaction_10072677", "reaction_10072715", "reaction_10072685", "reaction_10072081", "reaction_10072713" ] }, "R-BTA-5673000": { "id": "pathway_10094566", "reactome": "R-BTA-5673000", "name": "RAF activation", "reactions": [ "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10073904", "reaction_10074088", "reaction_10073940", "reaction_10073917", "reaction_10073932", "reaction_10073921", "reaction_10091548" ] }, "R-BTA-5628897": { "id": "pathway_10092468", "reactome": "R-BTA-5628897", "name": "TP53 Regulates Metabolic Genes", "reactions": [ "reaction_10033755", "reaction_10072595", "reaction_10034166", "reaction_10072591", "reaction_10072571", "reaction_10033592", "reaction_10072557", "reaction_10072614", "reaction_10046588", "reaction_10038647" ] }, "R-BTA-425393": { "id": "pathway_10093484", "reactome": "R-BTA-425393", "name": "Transport of inorganic cations/anions and amino acids/oligopeptides", "reactions": [ "reaction_10085384", "reaction_10048740", "reaction_10048550", "reaction_10049173", "reaction_10048533", "reaction_10048754", "reaction_10045501", "reaction_10048594", "reaction_10048478", "reaction_10044962", "reaction_10072522", "reaction_10045473", "reaction_10085896", "reaction_10048802", "reaction_10048761", "reaction_10048795", "reaction_10048504", "reaction_10049170", "reaction_10048618", "reaction_10048601", "reaction_10045487", "reaction_10048727", "reaction_10048821", "reaction_10048567", "reaction_10049083", "reaction_10048965", "reaction_10048768", "reaction_10044964", "reaction_10045494", "reaction_10044941", "reaction_10048491", "reaction_10048526", "reaction_10044971", "reaction_10060218", "reaction_10048747", "reaction_10048804", "reaction_10045480", "reaction_10044934", "reaction_10088905", "reaction_10044985", "reaction_10045050", "reaction_10048958", "reaction_10044948", "reaction_10044978", "reaction_10044955", "reaction_10085967" ] }, "R-BTA-5627123": { "id": "pathway_10094202", "reactome": "R-BTA-5627123", "name": "RHO GTPases activate PAKs", "reactions": [ "reaction_10063353" ] }, "R-BTA-111932": { "id": "pathway_10092782", "reactome": "R-BTA-111932", "name": "CaMK IV-mediated phosphorylation of CREB", "reactions": [ "reaction_10049478", "reaction_10036981" ] }, "R-BTA-5674135": { "id": "pathway_10094574", "reactome": "R-BTA-5674135", "name": "MAP2K and MAPK activation", "reactions": [ "reaction_10091570", "reaction_10091576", "reaction_10074129", "reaction_10074137", "reaction_10091572", "reaction_10074176", "reaction_10074195", "reaction_10091568" ] }, "R-BTA-111471": { "id": "pathway_10092822", "reactome": "R-BTA-111471", "name": "Apoptotic factor-mediated response", "reactions": [ "reaction_10037253", "reaction_10091188", "reaction_10037289", "reaction_10091191", "reaction_10037264", "reaction_10037293", "reaction_10091197", "reaction_10081897", "reaction_10091186" ] }, "R-BTA-73933": { "id": "pathway_10094852", "reactome": "R-BTA-73933", "name": "Resolution of Abasic Sites (AP sites)", "reactions": [ "reaction_10088526" ] }, "R-BTA-389359": { "id": "pathway_10093574", "reactome": "R-BTA-389359", "name": "CD28 dependent Vav1 pathway", "reactions": [ "reaction_10046822", "reaction_10046943" ] }, "R-BTA-83936": { "id": "pathway_10092726", "reactome": "R-BTA-83936", "name": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "reactions": [ "reaction_10036297", "reaction_10071001", "reaction_10071003", "reaction_10070991", "reaction_10036274", "reaction_10038660", "reaction_10036283", "reaction_10036276", "reaction_10051545", "reaction_10036290", "reaction_10051547", "reaction_10073838" ] }, "R-BTA-1299344": { "id": "pathway_10094058", "reactome": "R-BTA-1299344", "name": "TWIK-related spinal cord K+ channel (TRESK)", "reactions": [ "reaction_10057665" ] }, "R-BTA-159418": { "id": "pathway_10092926", "reactome": "R-BTA-159418", "name": "Recycling of bile acids and salts", "reactions": [ "reaction_10041437", "reaction_10085806", "reaction_10038347" ] }, "R-BTA-1296052": { "id": "pathway_10094030", "reactome": "R-BTA-1296052", "name": "Ca2+ activated K+ channels", "reactions": [ "reaction_10057365" ] }, "R-BTA-2514859": { "id": "pathway_10092654", "reactome": "R-BTA-2514859", "name": "Inactivation, recovery and regulation of the phototransduction cascade", "reactions": [ "reaction_10035596", "reaction_10065944", "reaction_10065808", "reaction_10035619", "reaction_10077744", "reaction_10065940" ] }, "R-BTA-159424": { "id": "pathway_10092934", "reactome": "R-BTA-159424", "name": "Conjugation of carboxylic acids", "reactions": [ "reaction_10038382", "reaction_10038380", "reaction_10038371", "reaction_10038354", "reaction_10040185" ] }, "R-BTA-1187000": { "id": "pathway_10094048", "reactome": "R-BTA-1187000", "name": "Fertilization", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10057605", "reaction_10057598", "reaction_10065827", "reaction_10065866" ] }, "R-BTA-8849470": { "id": "pathway_10094734", "reactome": "R-BTA-8849470", "name": "PTK6 Regulates Cell Cycle", "reactions": [ "reaction_10083565", "reaction_10083558" ] }, "R-BTA-168928": { "id": "pathway_10093902", "reactome": "R-BTA-168928", "name": "DDX58/IFIH1-mediated induction of interferon-alpha/beta", "reactions": [ "reaction_10056090", "reaction_10053134", "reaction_10053046", "reaction_10056084", "reaction_10053095", "reaction_10092318", "reaction_10053058", "reaction_10053048", "reaction_10056082", "reaction_10056088", "reaction_10053122" ] }, "R-BTA-425410": { "id": "pathway_10093758", "reactome": "R-BTA-425410", "name": "Metal ion SLC transporters", "reactions": [ "reaction_10049371", "reaction_10049392", "reaction_10049402", "reaction_10049378", "reaction_10049440", "reaction_10049385", "reaction_10088912", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-139853": { "id": "pathway_10092848", "reactome": "R-BTA-139853", "name": "Elevation of cytosolic Ca2+ levels", "reactions": [ "reaction_10048635", "reaction_10037607" ] }, "R-BTA-4085001": { "id": "pathway_10093730", "reactome": "R-BTA-4085001", "name": "Sialic acid metabolism", "reactions": [ "reaction_10069373", "reaction_10069382", "reaction_10069329", "reaction_10069346", "reaction_10069371", "reaction_10051554", "reaction_10069348", "reaction_10069368", "reaction_10048958", "reaction_10069320", "reaction_10069359", "reaction_10069357" ] }, "R-BTA-5693606": { "id": "pathway_10092658", "reactome": "R-BTA-5693606", "name": "DNA Double Strand Break Response", "reactions": [ "reaction_10076334", "reaction_10076298", "reaction_10074550", "reaction_10074670", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10074720", "reaction_10035720", "reaction_10074747", "reaction_10076303", "reaction_10074677", "reaction_10074695", "reaction_10035712", "reaction_10076329", "reaction_10076341", "reaction_10076343", "reaction_10074453", "reaction_10074692", "reaction_10076332", "reaction_10074759", "reaction_10074736", "reaction_10068854", "reaction_10074761", "reaction_10074679", "reaction_10075173" ] }, "R-BTA-8936459": { "id": "pathway_10094812", "reactome": "R-BTA-8936459", "name": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "reactions": [ "reaction_10086534", "reaction_10086518", "reaction_10086458", "reaction_10086525", "reaction_10086509", "reaction_10086493", "reaction_10086502", "reaction_10086541" ] }, "R-BTA-9025094": { "id": "pathway_10094932", "reactome": "R-BTA-9025094", "name": "Biosynthesis of DPAn-3 SPMs", "reactions": [ "reaction_10090472", "reaction_10090477", "reaction_10090474", "reaction_10090470" ] }, "R-BTA-9020702": { "id": "pathway_10093398", "reactome": "R-BTA-9020702", "name": "Interleukin-1 signaling", "reactions": [ "reaction_10091757", "reaction_10049721", "reaction_10050428", "reaction_10051095", "reaction_10043867", "reaction_10050420" ] }, "R-BTA-168256": { "id": "pathway_10093006", "reactome": "R-BTA-168256", "name": "Immune System", "reactions": [ "reaction_10051936", "reaction_10065009", "reaction_10043302", "reaction_10050196", "reaction_10066551", "reaction_10056268", "reaction_10089466", "reaction_10054791", "reaction_10072364", "reaction_10065051", "reaction_10092165", "reaction_10063374", "reaction_10077921", "reaction_10066141", "reaction_10077790", "reaction_10051966", "reaction_10072045", "reaction_10065413", "reaction_10073690", "reaction_10051786", "reaction_10089329", "reaction_10092257", "reaction_10092043", "reaction_10039217", "reaction_10061502", "reaction_10077843", "reaction_10080842", "reaction_10089480", "reaction_10086405", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10055491", "reaction_10056084", "reaction_10087787", "reaction_10089341", "reaction_10081385", "reaction_10087671", "reaction_10082967", "reaction_10060783", "reaction_10055958", "reaction_10089321", "reaction_10089516", "reaction_10084658", "reaction_10089333", "reaction_10073757", "reaction_10089536", "reaction_10055453", "reaction_10050254", "reaction_10052343", "reaction_10072383", "reaction_10089523", "reaction_10087774", "reaction_10089530", "reaction_10046903", "reaction_10065011", "reaction_10058492", "reaction_10081404", "reaction_10091723", "reaction_10074312", "reaction_10089591", "reaction_10056178", "reaction_10084683", "reaction_10056912", "reaction_10089311", "reaction_10055955", "reaction_10056199", "reaction_10081943", "reaction_10091743", "reaction_10050256", "reaction_10067225", "reaction_10084636", "reaction_10089453", "reaction_10089689", "reaction_10054649", "reaction_10055971", "reaction_10079391", "reaction_10065642", "reaction_10074993", "reaction_10060773", "reaction_10056914", "reaction_10081905", "reaction_10089349", "reaction_10056132", "reaction_10053122", "reaction_10072053", "reaction_10051771", "reaction_10089511", "reaction_10043193", "reaction_10077926", "reaction_10065491", "reaction_10052229", "reaction_10082008", "reaction_10050623", "reaction_10056315", "reaction_10089542", "reaction_10066880", "reaction_10056335", "reaction_10053095", "reaction_10050428", "reaction_10060412", "reaction_10056283", "reaction_10089736", "reaction_10089269", "reaction_10084322", "reaction_10089597", "reaction_10089331", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10089812", "reaction_10066168", "reaction_10077870", "reaction_10050619", "reaction_10055819", "reaction_10066532", "reaction_10063376", "reaction_10078759", "reaction_10051696", "reaction_10066536", "reaction_10046932", "reaction_10055448", "reaction_10067223", "reaction_10050231", "reaction_10042826", "reaction_10065402", "reaction_10046909", "reaction_10063353", "reaction_10042129", "reaction_10090919", "reaction_10090400", "reaction_10090844", "reaction_10083100", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10067233", "reaction_10072057", "reaction_10064219", "reaction_10082012", "reaction_10052217", "reaction_10051196", "reaction_10052325", "reaction_10057004", "reaction_10089267", "reaction_10039465", "reaction_10089625", "reaction_10079199", "reaction_10056910", "reaction_10092126", "reaction_10051737", "reaction_10089431", "reaction_10061657", "reaction_10056172", "reaction_10087780", "reaction_10075923", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10090031", "reaction_10056287", "reaction_10052210", "reaction_10057834", "reaction_10080063", "reaction_10089819", "reaction_10091747", "reaction_10077924", "reaction_10041950", "reaction_10066127", "reaction_10054779", "reaction_10039778", "reaction_10072002", "reaction_10089538", "reaction_10066059", "reaction_10064068", "reaction_10081406", "reaction_10084867", "reaction_10051818", "reaction_10052735", "reaction_10066052", "reaction_10089446", "reaction_10066147", "reaction_10089444", "reaction_10090916", "reaction_10092195", "reaction_10043867", "reaction_10074899", "reaction_10055431", "reaction_10077723", "reaction_10056539", "reaction_10081432", "reaction_10055817", "reaction_10092183", "reaction_10089621", "reaction_10084020", "reaction_10092151", "reaction_10072006", "reaction_10041863", "reaction_10092147", "reaction_10050028", "reaction_10076165", "reaction_10056835", "reaction_10050527", "reaction_10087766", "reaction_10047907", "reaction_10083522", "reaction_10082183", "reaction_10051792", "reaction_10056082", "reaction_10084672", "reaction_10050420", "reaction_10087650", "reaction_10042786", "reaction_10052327", "reaction_10065388", "reaction_10076237", "reaction_10089427", "reaction_10074306", "reaction_10092141", "reaction_10043241", "reaction_10052240", "reaction_10092137", "reaction_10046834", "reaction_10056102", "reaction_10049721", "reaction_10087797", "reaction_10046951", "reaction_10077764", "reaction_10084865", "reaction_10089363", "reaction_10081085", "reaction_10056297", "reaction_10077904", "reaction_10072395", "reaction_10056127", "reaction_10052321", "reaction_10066144", "reaction_10074266", "reaction_10066102", "reaction_10055821", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10080844", "reaction_10043300", "reaction_10089691", "reaction_10072388", "reaction_10056088", "reaction_10070719", "reaction_10052196", "reaction_10050011", "reaction_10080435", "reaction_10042253", "reaction_10081397", "reaction_10087783", "reaction_10087763", "reaction_10056416", "reaction_10051774", "reaction_10043659", "reaction_10049970", "reaction_10065055", "reaction_10083537", "reaction_10087823", "reaction_10043274", "reaction_10089843", "reaction_10063972", "reaction_10047530", "reaction_10077945", "reaction_10053058", "reaction_10079949", "reaction_10077422", "reaction_10071975", "reaction_10074340", "reaction_10091757", "reaction_10065227", "reaction_10042623", "reaction_10087795", "reaction_10089251", "reaction_10046787", "reaction_10049946", "reaction_10051962", "reaction_10091731", "reaction_10070906", "reaction_10074901", "reaction_10072374", "reaction_10066180", "reaction_10066151", "reaction_10056130", "reaction_10081559", "reaction_10043304", "reaction_10067229", "reaction_10090027", "reaction_10072061", "reaction_10043270", "reaction_10058486", "reaction_10078929", "reaction_10077633", "reaction_10055451", "reaction_10043244", "reaction_10074318", "reaction_10056982", "reaction_10080831", "reaction_10066172", "reaction_10080719", "reaction_10065019", "reaction_10052147", "reaction_10092318", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10087663", "reaction_10092033", "reaction_10050208", "reaction_10052471", "reaction_10060730", "reaction_10060759", "reaction_10039508", "reaction_10077919", "reaction_10046822", "reaction_10052233", "reaction_10056090", "reaction_10052189", "reaction_10052466", "reaction_10045016", "reaction_10058456", "reaction_10089595", "reaction_10066608", "reaction_10081506", "reaction_10087726", "reaction_10092040", "reaction_10057836", "reaction_10064277", "reaction_10050024", "reaction_10088519", "reaction_10075009", "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10052213", "reaction_10051762", "reaction_10052254", "reaction_10056531", "reaction_10053134", "reaction_10089506", "reaction_10053213", "reaction_10056205", "reaction_10089442", "reaction_10046807", "reaction_10066094", "reaction_10046888", "reaction_10083967", "reaction_10081265", "reaction_10081510", "reaction_10051836", "reaction_10043262", "reaction_10043212", "reaction_10065407", "reaction_10056805", "reaction_10053048", "reaction_10074280", "reaction_10074314", "reaction_10072011", "reaction_10092108", "reaction_10055783", "reaction_10089291", "reaction_10083106", "reaction_10040197", "reaction_10087789", "reaction_10085369", "reaction_10089615", "reaction_10092139", "reaction_10056170", "reaction_10054678", "reaction_10056110", "reaction_10071982", "reaction_10089540", "reaction_10043219", "reaction_10087732", "reaction_10050218", "reaction_10051095", "reaction_10052067", "reaction_10083959", "reaction_10043182", "reaction_10065517", "reaction_10066082", "reaction_10055444", "reaction_10060785", "reaction_10089253", "reaction_10065894", "reaction_10084706", "reaction_10050192", "reaction_10043298", "reaction_10056188", "reaction_10066238", "reaction_10092173", "reaction_10077455", "reaction_10081410", "reaction_10066080", "reaction_10056239", "reaction_10089455", "reaction_10046959", "reaction_10064214", "reaction_10079653", "reaction_10057823", "reaction_10056289", "reaction_10064221", "reaction_10056194", "reaction_10055946", "reaction_10066120", "reaction_10055967", "reaction_10056176", "reaction_10061174", "reaction_10074320", "reaction_10052236", "reaction_10056903", "reaction_10060694", "reaction_10076963", "reaction_10082977", "reaction_10051780", "reaction_10084305", "reaction_10065021", "reaction_10051748", "reaction_10073765", "reaction_10082004", "reaction_10050054", "reaction_10090019", "reaction_10087338", "reaction_10043252", "reaction_10087807", "reaction_10058388", "reaction_10091725", "reaction_10055460", "reaction_10056207", "reaction_10046907", "reaction_10046943", "reaction_10066559", "reaction_10039782", "reaction_10056123", "reaction_10052323", "reaction_10047519", "reaction_10039481", "reaction_10089703", "reaction_10054736", "reaction_10091817", "reaction_10054866", "reaction_10049928", "reaction_10073708", "reaction_10071948", "reaction_10067231", "reaction_10089696", "reaction_10052159", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10063368", "reaction_10092143", "reaction_10051949", "reaction_10092159", "reaction_10074308", "reaction_10088498", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074310", "reaction_10084401", "reaction_10049983", "reaction_10042635", "reaction_10054524", "reaction_10064118", "reaction_10053046", "reaction_10047536", "reaction_10085017", "reaction_10051954", "reaction_10072392", "reaction_10046811", "reaction_10052302" ] }, "R-BTA-429914": { "id": "pathway_10093742", "reactome": "R-BTA-429914", "name": "Deadenylation-dependent mRNA decay", "reactions": [ "reaction_10049230", "reaction_10049232" ] }, "R-BTA-1855231": { "id": "pathway_10094176", "reactome": "R-BTA-1855231", "name": "Synthesis of IPs in the ER lumen", "reactions": [ "reaction_10060963", "reaction_10061122", "reaction_10061043" ] }, "R-BTA-5676594": { "id": "pathway_10094560", "reactome": "R-BTA-5676594", "name": "TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway", "reactions": [ "reaction_10073757", "reaction_10074308", "reaction_10074320", "reaction_10074316", "reaction_10074306", "reaction_10074318", "reaction_10074314", "reaction_10074310", "reaction_10074312" ] }, "R-BTA-73817": { "id": "pathway_10092606", "reactome": "R-BTA-73817", "name": "Purine ribonucleoside monophosphate biosynthesis", "reactions": [ "reaction_10035332", "reaction_10035354", "reaction_10035339", "reaction_10036907", "reaction_10036928", "reaction_10036909", "reaction_10035308", "reaction_10091727", "reaction_10035345", "reaction_10035342", "reaction_10035329", "reaction_10035319" ] }, "R-BTA-5693571": { "id": "pathway_10094604", "reactome": "R-BTA-5693571", "name": "Nonhomologous End-Joining (NHEJ)", "reactions": [ "reaction_10076347", "reaction_10076327", "reaction_10075295", "reaction_10076312", "reaction_10076286" ] }, "R-BTA-5688426": { "id": "pathway_10094374", "reactome": "R-BTA-5688426", "name": "Deubiquitination", "reactions": [ "reaction_10075808", "reaction_10075550", "reaction_10077363", "reaction_10085345", "reaction_10075942", "reaction_10084931", "reaction_10077393", "reaction_10077034", "reaction_10075989", "reaction_10075970", "reaction_10077292", "reaction_10077371", "reaction_10076001", "reaction_10075891", "reaction_10077070", "reaction_10076119", "reaction_10077331", "reaction_10075902", "reaction_10075397", "reaction_10075374", "reaction_10075952", "reaction_10077349", "reaction_10076112", "reaction_10068095", "reaction_10077406", "reaction_10075984", "reaction_10077339", "reaction_10075561", "reaction_10077317", "reaction_10077379" ] }, "R-BTA-9018519": { "id": "pathway_10094882", "reactome": "R-BTA-9018519", "name": "Estrogen-dependent gene expression", "reactions": [ "reaction_10089761" ] }, "R-BTA-9711097": { "id": "pathway_10095010", "reactome": "R-BTA-9711097", "name": "Cellular response to starvation", "reactions": [ "reaction_10091354", "reaction_10091356", "reaction_10091336", "reaction_10091365", "reaction_10091351", "reaction_10091401", "reaction_10091404" ] }, "R-BTA-2995383": { "id": "pathway_10094998", "reactome": "R-BTA-2995383", "name": "Initiation of Nuclear Envelope (NE) Reformation", "reactions": [ "reaction_10091132" ] }, "R-BTA-3215018": { "id": "pathway_10094324", "reactome": "R-BTA-3215018", "name": "Processing and activation of SUMO", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-73614": { "id": "pathway_10092594", "reactome": "R-BTA-73614", "name": "Pyrimidine salvage", "reactions": [ "reaction_10088624", "reaction_10035020", "reaction_10034989", "reaction_10036649", "reaction_10034980", "reaction_10035479", "reaction_10036614", "reaction_10035007" ] }, "R-BTA-5696398": { "id": "pathway_10092746", "reactome": "R-BTA-5696398", "name": "Nucleotide Excision Repair", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10077016", "reaction_10076071", "reaction_10076009", "reaction_10036661" ] }, "R-BTA-201688": { "id": "pathway_10094378", "reactome": "R-BTA-201688", "name": "WNT mediated activation of DVL", "reactions": [ "reaction_10068707", "reaction_10068704" ] }, "R-BTA-8864260": { "id": "pathway_10093536", "reactome": "R-BTA-8864260", "name": "Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors", "reactions": [ "reaction_10084911", "reaction_10084935", "reaction_10084881", "reaction_10084922", "reaction_10084909", "reaction_10045744", "reaction_10084903", "reaction_10084895" ] }, "R-BTA-2029482": { "id": "pathway_10094200", "reactome": "R-BTA-2029482", "name": "Regulation of actin dynamics for phagocytic cup formation", "reactions": [ "reaction_10063374", "reaction_10063353" ] }, "R-BTA-111463": { "id": "pathway_10092830", "reactome": "R-BTA-111463", "name": "SMAC (DIABLO) binds to IAPs ", "reactions": [ "reaction_10091191", "reaction_10037289" ] }, "R-BTA-8956320": { "id": "pathway_10092586", "reactome": "R-BTA-8956320", "name": "Nucleobase biosynthesis", "reactions": [ "reaction_10034927", "reaction_10035342", "reaction_10035332", "reaction_10034921", "reaction_10035354", "reaction_10035339", "reaction_10036907", "reaction_10036928", "reaction_10036909", "reaction_10035308", "reaction_10091727", "reaction_10035345", "reaction_10034924", "reaction_10035329", "reaction_10035319" ] }, "R-BTA-5693548": { "id": "pathway_10092656", "reactome": "R-BTA-5693548", "name": "Sensing of DNA Double Strand Breaks", "reactions": [ "reaction_10035720", "reaction_10068854", "reaction_10035712", "reaction_10076298", "reaction_10076343", "reaction_10074453", "reaction_10074761", "reaction_10074759" ] }, "R-BTA-435368": { "id": "pathway_10093760", "reactome": "R-BTA-435368", "name": "Zinc efflux and compartmentalization by the SLC30 family", "reactions": [ "reaction_10049385", "reaction_10049392", "reaction_10049378" ] }, "R-BTA-1483226": { "id": "pathway_10094110", "reactome": "R-BTA-1483226", "name": "Synthesis of PI", "reactions": [ "reaction_10085340", "reaction_10059091", "reaction_10059044" ] }, "R-BTA-444257": { "id": "pathway_10094948", "reactome": "R-BTA-444257", "name": "RSK activation", "reactions": [ "reaction_10090547" ] }, "R-BTA-73928": { "id": "pathway_10092750", "reactome": "R-BTA-73928", "name": "Depyrimidination", "reactions": [ "reaction_10036716", "reaction_10036767", "reaction_10036709", "reaction_10036729", "reaction_10036736", "reaction_10036743" ] }, "R-BTA-2730905": { "id": "pathway_10093352", "reactome": "R-BTA-2730905", "name": "Role of LAT2/NTAL/LAB on calcium mobilization", "reactions": [ "reaction_10066144", "reaction_10043182", "reaction_10066080" ] }, "R-BTA-3000157": { "id": "pathway_10093448", "reactome": "R-BTA-3000157", "name": "Laminin interactions", "reactions": [ "reaction_10069313", "reaction_10044515", "reaction_10065555" ] }, "R-BTA-983712": { "id": "pathway_10093672", "reactome": "R-BTA-983712", "name": "Ion channel transport", "reactions": [ "reaction_10091583", "reaction_10066232", "reaction_10076179", "reaction_10067346", "reaction_10091542", "reaction_10071254", "reaction_10066282", "reaction_10092050", "reaction_10066270", "reaction_10066227", "reaction_10066004", "reaction_10047893", "reaction_10076172", "reaction_10053143", "reaction_10048787", "reaction_10066199", "reaction_10053258", "reaction_10066034", "reaction_10066021", "reaction_10053180", "reaction_10084767", "reaction_10053210", "reaction_10047900", "reaction_10066289", "reaction_10067332", "reaction_10065965", "reaction_10066277", "reaction_10065991", "reaction_10091759", "reaction_10066206" ] }, "R-BTA-9706374": { "id": "pathway_10095036", "reactome": "R-BTA-9706374", "name": "FLT3 signaling through SRC family kinases", "reactions": [ "reaction_10092151" ] }, "R-BTA-2022870": { "id": "pathway_10094192", "reactome": "R-BTA-2022870", "name": "Chondroitin sulfate biosynthesis", "reactions": [ "reaction_10061642", "reaction_10062463", "reaction_10061651", "reaction_10063014", "reaction_10061612" ] }, "R-BTA-203615": { "id": "pathway_10094626", "reactome": "R-BTA-203615", "name": "eNOS activation", "reactions": [ "reaction_10076274" ] }, "R-BTA-9640463": { "id": "pathway_10093598", "reactome": "R-BTA-9640463", "name": "Wax biosynthesis", "reactions": [ "reaction_10047065", "reaction_10077001", "reaction_10083575", "reaction_10083577" ] }, "R-BTA-5696394": { "id": "pathway_10094622", "reactome": "R-BTA-5696394", "name": "DNA Damage Recognition in GG-NER", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10076009", "reaction_10076071" ] }, "R-BTA-5625900": { "id": "pathway_10094564", "reactome": "R-BTA-5625900", "name": "RHO GTPases activate CIT", "reactions": [ "reaction_10073796", "reaction_10073806" ] }, "R-BTA-111465": { "id": "pathway_10093340", "reactome": "R-BTA-111465", "name": "Apoptotic cleavage of cellular proteins", "reactions": [ "reaction_10044756", "reaction_10044762", "reaction_10044995", "reaction_10044568", "reaction_10044896", "reaction_10090575", "reaction_10043049", "reaction_10043059", "reaction_10044578", "reaction_10043021", "reaction_10090573", "reaction_10044906", "reaction_10044923", "reaction_10043039" ] }, "R-BTA-2559585": { "id": "pathway_10093140", "reactome": "R-BTA-2559585", "name": "Oncogene Induced Senescence", "reactions": [ "reaction_10066630", "reaction_10040355" ] }, "R-BTA-9012999": { "id": "pathway_10094864", "reactome": "R-BTA-9012999", "name": "RHO GTPase cycle", "reactions": [ "reaction_10089937", "reaction_10090330", "reaction_10090145", "reaction_10090306", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10090087", "reaction_10089888", "reaction_10090119", "reaction_10090103", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10090082", "reaction_10090125", "reaction_10090339", "reaction_10090089", "reaction_10091994", "reaction_10091921", "reaction_10089972", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10089930", "reaction_10090349", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10091884", "reaction_10090198", "reaction_10089947", "reaction_10092392", "reaction_10090077", "reaction_10091896", "reaction_10092382", "reaction_10092022", "reaction_10089011", "reaction_10090115", "reaction_10090369", "reaction_10090246", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10089985", "reaction_10092370", "reaction_10090098", "reaction_10090266", "reaction_10089149", "reaction_10091864", "reaction_10089952", "reaction_10092020" ] }, "R-BTA-69306": { "id": "pathway_10092402", "reactome": "R-BTA-69306", "name": "DNA Replication", "reactions": [ "reaction_10033379", "reaction_10033512", "reaction_10033504", "reaction_10040183", "reaction_10033466", "reaction_10033412", "reaction_10033473" ] }, "R-BTA-4086400": { "id": "pathway_10094382", "reactome": "R-BTA-4086400", "name": "PCP/CE pathway", "reactions": [ "reaction_10068923", "reaction_10069882", "reaction_10068933", "reaction_10069876", "reaction_10069896", "reaction_10068939", "reaction_10069593", "reaction_10069299", "reaction_10069872", "reaction_10069595" ] }, "R-BTA-9603381": { "id": "pathway_10094968", "reactome": "R-BTA-9603381", "name": "Activated NTRK3 signals through PI3K", "reactions": [ "reaction_10090727", "reaction_10090722" ] }, "R-BTA-196780": { "id": "pathway_10093320", "reactome": "R-BTA-196780", "name": "Biotin transport and metabolism", "reactions": [ "reaction_10066401", "reaction_10067733", "reaction_10042657" ] }, "R-BTA-500792": { "id": "pathway_10092986", "reactome": "R-BTA-500792", "name": "GPCR ligand binding", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048304", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10049643", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10086565", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10049681", "reaction_10067358", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-1296067": { "id": "pathway_10094034", "reactome": "R-BTA-1296067", "name": "Potassium transport channels", "reactions": [ "reaction_10057399" ] }, "R-BTA-1299287": { "id": "pathway_10094052", "reactome": "R-BTA-1299287", "name": "Tandem pore domain halothane-inhibited K+ channel (THIK)", "reactions": [ "reaction_10057616" ] }, "R-BTA-189445": { "id": "pathway_10092922", "reactome": "R-BTA-189445", "name": "Metabolism of porphyrins", "reactions": [ "reaction_10038338", "reaction_10040682", "reaction_10091613", "reaction_10040636", "reaction_10040688", "reaction_10038336", "reaction_10091598", "reaction_10091611", "reaction_10040672", "reaction_10040645", "reaction_10040663", "reaction_10040654", "reaction_10091605", "reaction_10066416" ] }, "R-BTA-6804114": { "id": "pathway_10094656", "reactome": "R-BTA-6804114", "name": "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest", "reactions": [ "reaction_10077955", "reaction_10078349", "reaction_10081499" ] }, "R-BTA-446205": { "id": "pathway_10093778", "reactome": "R-BTA-446205", "name": "Synthesis of GDP-mannose", "reactions": [ "reaction_10049831" ] }, "R-BTA-428890": { "id": "pathway_10093526", "reactome": "R-BTA-428890", "name": "Role of ABL in ROBO-SLIT signaling", "reactions": [ "reaction_10045517", "reaction_10049024" ] }, "R-BTA-379401": { "id": "pathway_10093540", "reactome": "R-BTA-379401", "name": "Dopamine clearance from the synaptic cleft", "reactions": [ "reaction_10046151", "reaction_10046153", "reaction_10088657" ] }, "R-BTA-9670095": { "id": "pathway_10095020", "reactome": "R-BTA-9670095", "name": "Inhibition of DNA recombination at telomere", "reactions": [ "reaction_10091685" ] }, "R-BTA-6783589": { "id": "pathway_10093962", "reactome": "R-BTA-6783589", "name": "Interleukin-6 family signaling", "reactions": [ "reaction_10056207", "reaction_10056201", "reaction_10056127", "reaction_10056130", "reaction_10056188", "reaction_10056123", "reaction_10077455", "reaction_10056178", "reaction_10056205", "reaction_10056199", "reaction_10077422", "reaction_10056170", "reaction_10056194", "reaction_10056110", "reaction_10056176", "reaction_10056172", "reaction_10056168", "reaction_10056132", "reaction_10056185", "reaction_10056102", "reaction_10091747", "reaction_10077424" ] }, "R-BTA-9020956": { "id": "pathway_10093786", "reactome": "R-BTA-9020956", "name": "Interleukin-27 signaling", "reactions": [ "reaction_10049970", "reaction_10087766", "reaction_10087783", "reaction_10087726", "reaction_10087787", "reaction_10087793", "reaction_10087671", "reaction_10087774", "reaction_10049946" ] }, "R-BTA-8939236": { "id": "pathway_10094858", "reactome": "R-BTA-8939236", "name": "RUNX1 regulates transcription of genes involved in differentiation of HSCs", "reactions": [ "reaction_10088872", "reaction_10088876", "reaction_10088887" ] }, "R-BTA-6803205": { "id": "pathway_10094674", "reactome": "R-BTA-6803205", "name": "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain", "reactions": [ "reaction_10080789", "reaction_10080738" ] }, "R-BTA-157858": { "id": "pathway_10093210", "reactome": "R-BTA-157858", "name": "Gap junction trafficking and regulation", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040967", "reaction_10040842", "reaction_10040961", "reaction_10040955", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-192105": { "id": "pathway_10093236", "reactome": "R-BTA-192105", "name": "Synthesis of bile acids and bile salts", "reactions": [ "reaction_10041337", "reaction_10041197", "reaction_10041377", "reaction_10041172", "reaction_10041308", "reaction_10041343", "reaction_10041363", "reaction_10041177", "reaction_10041208", "reaction_10085316", "reaction_10041104", "reaction_10041357", "reaction_10085291", "reaction_10041226", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041323", "reaction_10041349", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041351", "reaction_10041371", "reaction_10041375", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041335", "reaction_10041210", "reaction_10041327", "reaction_10041193", "reaction_10041353", "reaction_10041317", "reaction_10041361", "reaction_10041345", "reaction_10041204", "reaction_10041319", "reaction_10041367", "reaction_10041339", "reaction_10041097", "reaction_10041179", "reaction_10041217", "reaction_10041206", "reaction_10041301", "reaction_10041373", "reaction_10041195", "reaction_10041369" ] }, "R-BTA-190840": { "id": "pathway_10093202", "reactome": "R-BTA-190840", "name": "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane", "reactions": [ "reaction_10040842", "reaction_10040857" ] }, "R-BTA-72695": { "id": "pathway_10092580", "reactome": "R-BTA-72695", "name": "Formation of the ternary complex, and subsequently, the 43S complex", "reactions": [ "reaction_10034387", "reaction_10034383", "reaction_10034905" ] }, "R-BTA-427413": { "id": "pathway_10093712", "reactome": "R-BTA-427413", "name": "NoRC negatively regulates rRNA expression", "reactions": [ "reaction_10048682" ] }, "R-BTA-9674555": { "id": "pathway_10095034", "reactome": "R-BTA-9674555", "name": "Signaling by CSF3 (G-CSF)", "reactions": [ "reaction_10092257", "reaction_10092108" ] }, "R-BTA-5576891": { "id": "pathway_10093668", "reactome": "R-BTA-5576891", "name": "Cardiac conduction", "reactions": [ "reaction_10048504", "reaction_10057418", "reaction_10071819", "reaction_10071843", "reaction_10077468", "reaction_10047893", "reaction_10071824", "reaction_10053180", "reaction_10048787", "reaction_10071800", "reaction_10091759", "reaction_10071876" ] }, "R-BTA-166786": { "id": "pathway_10093112", "reactome": "R-BTA-166786", "name": "Creation of C4 and C2 activators", "reactions": [ "reaction_10039782", "reaction_10039778" ] }, "R-BTA-9696270": { "id": "pathway_10095026", "reactome": "R-BTA-9696270", "name": "RND2 GTPase cycle", "reactions": [ "reaction_10091994", "reaction_10092022" ] }, "R-BTA-189085": { "id": "pathway_10093160", "reactome": "R-BTA-189085", "name": "Digestion of dietary carbohydrate", "reactions": [ "reaction_10040866", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10073378", "reaction_10040608", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-6799990": { "id": "pathway_10093980", "reactome": "R-BTA-6799990", "name": "Metal sequestration by antimicrobial proteins", "reactions": [ "reaction_10078759", "reaction_10056416", "reaction_10070906" ] }, "R-BTA-1169408": { "id": "pathway_10093970", "reactome": "R-BTA-1169408", "name": "ISG15 antiviral mechanism", "reactions": [ "reaction_10060730", "reaction_10060732", "reaction_10056315", "reaction_10056289", "reaction_10056283", "reaction_10060694", "reaction_10056287", "reaction_10056297" ] }, "R-BTA-376172": { "id": "pathway_10093522", "reactome": "R-BTA-376172", "name": "DSCAM interactions", "reactions": [ "reaction_10045509" ] }, "R-BTA-5689880": { "id": "pathway_10094372", "reactome": "R-BTA-5689880", "name": "Ub-specific processing proteases", "reactions": [ "reaction_10077034", "reaction_10077070", "reaction_10077349", "reaction_10068095", "reaction_10075808", "reaction_10075550", "reaction_10077292", "reaction_10077363", "reaction_10077331", "reaction_10077371", "reaction_10075902", "reaction_10077317", "reaction_10077339", "reaction_10075561", "reaction_10077393", "reaction_10075891", "reaction_10077379" ] }, "R-BTA-430039": { "id": "pathway_10093744", "reactome": "R-BTA-430039", "name": "mRNA decay by 5' to 3' exoribonuclease", "reactions": [ "reaction_10049232" ] }, "R-BTA-216083": { "id": "pathway_10093316", "reactome": "R-BTA-216083", "name": "Integrin cell surface interactions", "reactions": [ "reaction_10042253", "reaction_10069412" ] }, "R-BTA-5693567": { "id": "pathway_10092678", "reactome": "R-BTA-5693567", "name": "HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075151", "reaction_10076339", "reaction_10075037", "reaction_10035846", "reaction_10075181", "reaction_10074798" ] }, "R-BTA-110373": { "id": "pathway_10094850", "reactome": "R-BTA-110373", "name": "Resolution of AP sites via the multiple-nucleotide patch replacement pathway", "reactions": [ "reaction_10088526" ] }, "R-BTA-69656": { "id": "pathway_10093152", "reactome": "R-BTA-69656", "name": "Cyclin A:Cdk2-associated events at S phase entry", "reactions": [ "reaction_10040521", "reaction_10083565", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-975138": { "id": "pathway_10093024", "reactome": "R-BTA-975138", "name": "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-391906": { "id": "pathway_10093630", "reactome": "R-BTA-391906", "name": "Leukotriene receptors", "reactions": [ "reaction_10047396", "reaction_10047378", "reaction_10047398", "reaction_10091763", "reaction_10091812" ] }, "R-BTA-2046105": { "id": "pathway_10094216", "reactome": "R-BTA-2046105", "name": "Linoleic acid (LA) metabolism", "reactions": [ "reaction_10063450", "reaction_10063454", "reaction_10063413", "reaction_10063442", "reaction_10063446", "reaction_10063448", "reaction_10063444", "reaction_10063452" ] }, "R-BTA-194138": { "id": "pathway_10093158", "reactome": "R-BTA-194138", "name": "Signaling by VEGF", "reactions": [ "reaction_10070624", "reaction_10041649", "reaction_10071504", "reaction_10041463", "reaction_10070589", "reaction_10070628", "reaction_10071506", "reaction_10040570", "reaction_10069535", "reaction_10071508", "reaction_10070651", "reaction_10070645", "reaction_10041657", "reaction_10070594", "reaction_10070615", "reaction_10070676", "reaction_10070596", "reaction_10065227", "reaction_10070657", "reaction_10041453" ] }, "R-BTA-176408": { "id": "pathway_10092894", "reactome": "R-BTA-176408", "name": "Regulation of APC/C activators between G1/S and early anaphase", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-9619229": { "id": "pathway_10094990", "reactome": "R-BTA-9619229", "name": "Activation of RAC1 downstream of NMDARs", "reactions": [ "reaction_10091067", "reaction_10091075" ] }, "R-BTA-8963898": { "id": "pathway_10094580", "reactome": "R-BTA-8963898", "name": "Plasma lipoprotein assembly", "reactions": [ "reaction_10074486", "reaction_10074474" ] }, "R-BTA-68886": { "id": "pathway_10094260", "reactome": "R-BTA-68886", "name": "M Phase", "reactions": [ "reaction_10065708", "reaction_10066345", "reaction_10091132", "reaction_10065572", "reaction_10091656", "reaction_10065095", "reaction_10065563", "reaction_10091141", "reaction_10065794", "reaction_10070705", "reaction_10091661", "reaction_10064733", "reaction_10065177", "reaction_10064904", "reaction_10065201", "reaction_10069491", "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10091658", "reaction_10066324" ] }, "R-BTA-8854691": { "id": "pathway_10093792", "reactome": "R-BTA-8854691", "name": "Interleukin-20 family signaling", "reactions": [ "reaction_10089538", "reaction_10089542", "reaction_10089466", "reaction_10089506", "reaction_10089455", "reaction_10089442", "reaction_10089516", "reaction_10089446", "reaction_10089444", "reaction_10089453", "reaction_10089431", "reaction_10089540", "reaction_10089427", "reaction_10089536", "reaction_10089511", "reaction_10050054", "reaction_10089480", "reaction_10089523", "reaction_10089530" ] }, "R-BTA-2022090": { "id": "pathway_10094086", "reactome": "R-BTA-2022090", "name": "Assembly of collagen fibrils and other multimeric structures", "reactions": [ "reaction_10065929", "reaction_10058705", "reaction_10064953", "reaction_10064959" ] }, "R-BTA-74160": { "id": "pathway_10092440", "reactome": "R-BTA-74160", "name": "Gene expression (Transcription)", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10048682", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10071065", "reaction_10037185", "reaction_10048720", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10044390", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10081561", "reaction_10080457", "reaction_10035301", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10035854", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10044381", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10038904", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10035254", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10070702", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10070700", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10044333", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10044361", "reaction_10086502", "reaction_10091096", "reaction_10087862", "reaction_10046681", "reaction_10081499", "reaction_10048717", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10037201" ] }, "R-BTA-399954": { "id": "pathway_10093646", "reactome": "R-BTA-399954", "name": "Sema3A PAK dependent Axon repulsion", "reactions": [ "reaction_10047618", "reaction_10047763", "reaction_10047659" ] }, "R-BTA-5696395": { "id": "pathway_10092742", "reactome": "R-BTA-5696395", "name": "Formation of Incision Complex in GG-NER", "reactions": [ "reaction_10036661", "reaction_10077016" ] }, "R-BTA-1483148": { "id": "pathway_10094116", "reactome": "R-BTA-1483148", "name": "Synthesis of PG", "reactions": [ "reaction_10059101" ] }, "R-BTA-2142691": { "id": "pathway_10093434", "reactome": "R-BTA-2142691", "name": "Synthesis of Leukotrienes (LT) and Eoxins (EX)", "reactions": [ "reaction_10064482", "reaction_10064581", "reaction_10044657", "reaction_10064503", "reaction_10044151" ] }, "R-BTA-3858494": { "id": "pathway_10094384", "reactome": "R-BTA-3858494", "name": "Beta-catenin independent WNT signaling", "reactions": [ "reaction_10069456", "reaction_10069459", "reaction_10068923", "reaction_10069882", "reaction_10069448", "reaction_10068933", "reaction_10069876", "reaction_10069896", "reaction_10068939", "reaction_10069593", "reaction_10069299", "reaction_10069872", "reaction_10069595" ] }, "R-BTA-382551": { "id": "pathway_10092732", "reactome": "R-BTA-382551", "name": "Transport of small molecules", "reactions": [ "reaction_10052907", "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10066227", "reaction_10049371", "reaction_10086004", "reaction_10047893", "reaction_10053143", "reaction_10085994", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10052916", "reaction_10049319", "reaction_10066034", "reaction_10045494", "reaction_10081968", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10057062", "reaction_10066289", "reaction_10049080", "reaction_10049241", "reaction_10065991", "reaction_10091759", "reaction_10086343", "reaction_10044978", "reaction_10051892", "reaction_10076099", "reaction_10074474", "reaction_10087646", "reaction_10085907", "reaction_10052888", "reaction_10076179", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10074493", "reaction_10071462", "reaction_10045501", "reaction_10049464", "reaction_10057070", "reaction_10052923", "reaction_10045473", "reaction_10051136", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10066270", "reaction_10048795", "reaction_10086002", "reaction_10086026", "reaction_10066199", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10070728", "reaction_10059181", "reaction_10058792", "reaction_10051145", "reaction_10083113", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10067332", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10066277", "reaction_10052909", "reaction_10070906", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10049262", "reaction_10051547", "reaction_10074360", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10091542", "reaction_10071254", "reaction_10087365", "reaction_10070743", "reaction_10092050", "reaction_10044962", "reaction_10072522", "reaction_10051141", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10070735", "reaction_10048504", "reaction_10066004", "reaction_10057007", "reaction_10049440", "reaction_10044547", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10053258", "reaction_10051143", "reaction_10071490", "reaction_10049083", "reaction_10058790", "reaction_10048768", "reaction_10058216", "reaction_10058469", "reaction_10049378", "reaction_10040636", "reaction_10049869", "reaction_10044941", "reaction_10086557", "reaction_10053180", "reaction_10048491", "reaction_10084767", "reaction_10088982", "reaction_10051276", "reaction_10047900", "reaction_10074686", "reaction_10071469", "reaction_10044934", "reaction_10089029", "reaction_10051148", "reaction_10076091", "reaction_10065965", "reaction_10089048", "reaction_10049385", "reaction_10051545", "reaction_10066206", "reaction_10044955", "reaction_10091583", "reaction_10049243", "reaction_10074486", "reaction_10066232", "reaction_10085384", "reaction_10052925", "reaction_10067346", "reaction_10051587", "reaction_10048754", "reaction_10052866", "reaction_10066282", "reaction_10057832", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10052914", "reaction_10036297", "reaction_10071001", "reaction_10052901", "reaction_10051879", "reaction_10076083", "reaction_10046707", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10076172", "reaction_10048787", "reaction_10046698", "reaction_10051150", "reaction_10077487", "reaction_10049053", "reaction_10071280", "reaction_10048821", "reaction_10089060", "reaction_10049628", "reaction_10049447", "reaction_10044666", "reaction_10089058", "reaction_10071003", "reaction_10047483", "reaction_10049271", "reaction_10049253", "reaction_10066021", "reaction_10052911", "reaction_10071476", "reaction_10089062", "reaction_10051866", "reaction_10053210", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10084509", "reaction_10084300", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10077489", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-9033658": { "id": "pathway_10094960", "reactome": "R-BTA-9033658", "name": "Blood group systems biosynthesis", "reactions": [ "reaction_10090620", "reaction_10090631", "reaction_10090799", "reaction_10090774", "reaction_10090611", "reaction_10090645", "reaction_10090703", "reaction_10090867", "reaction_10090638", "reaction_10090797", "reaction_10090822", "reaction_10090854", "reaction_10090772", "reaction_10090856", "reaction_10090851", "reaction_10090819", "reaction_10090802" ] }, "R-BTA-597592": { "id": "pathway_10092946", "reactome": "R-BTA-597592", "name": "Post-translational protein modification", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10081490", "reaction_10049811", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10043698", "reaction_10088807", "reaction_10069329", "reaction_10069498", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10082038", "reaction_10083380", "reaction_10087883", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10077363", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10077034", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10076119", "reaction_10056074", "reaction_10076773", "reaction_10077331", "reaction_10082045", "reaction_10049831", "reaction_10038408", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10076610", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10049789", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10076586", "reaction_10040933", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10088734", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10048958", "reaction_10087848" ] }, "R-BTA-5663220": { "id": "pathway_10093364", "reactome": "R-BTA-5663220", "name": "RHO GTPases Activate Formins", "reactions": [ "reaction_10073549", "reaction_10073569", "reaction_10073561", "reaction_10073525", "reaction_10073547", "reaction_10068933", "reaction_10068939", "reaction_10043461", "reaction_10073493", "reaction_10073503", "reaction_10073507", "reaction_10073559", "reaction_10073557" ] }, "R-BTA-450302": { "id": "pathway_10093798", "reactome": "R-BTA-450302", "name": "activated TAK1 mediates p38 MAPK activation", "reactions": [ "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10050231" ] }, "R-BTA-73762": { "id": "pathway_10092604", "reactome": "R-BTA-73762", "name": "RNA Polymerase I Transcription Initiation", "reactions": [ "reaction_10035301" ] }, "R-BTA-156587": { "id": "pathway_10092936", "reactome": "R-BTA-156587", "name": "Amino Acid conjugation", "reactions": [ "reaction_10038382", "reaction_10038380", "reaction_10038371", "reaction_10038354", "reaction_10040185" ] }, "R-BTA-69895": { "id": "pathway_10094682", "reactome": "R-BTA-69895", "name": "Transcriptional activation of cell cycle inhibitor p21 ", "reactions": [ "reaction_10081470" ] }, "R-BTA-140875": { "id": "pathway_10092872", "reactome": "R-BTA-140875", "name": "Common Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10090181", "reaction_10037845", "reaction_10037923", "reaction_10037800", "reaction_10090183", "reaction_10037950", "reaction_10037815", "reaction_10037927", "reaction_10037948", "reaction_10071906", "reaction_10037852" ] }, "R-BTA-71336": { "id": "pathway_10092466", "reactome": "R-BTA-71336", "name": "Pentose phosphate pathway", "reactions": [ "reaction_10088898", "reaction_10034043", "reaction_10034041", "reaction_10034013", "reaction_10088744", "reaction_10089230", "reaction_10077793", "reaction_10034944", "reaction_10033592", "reaction_10034032", "reaction_10042801", "reaction_10036903" ] }, "R-BTA-5652084": { "id": "pathway_10092462", "reactome": "R-BTA-5652084", "name": "Fructose metabolism", "reactions": [ "reaction_10072825", "reaction_10083115", "reaction_10033570", "reaction_10033561" ] }, "R-BTA-5358351": { "id": "pathway_10094476", "reactome": "R-BTA-5358351", "name": "Signaling by Hedgehog", "reactions": [ "reaction_10072138", "reaction_10072220", "reaction_10072123", "reaction_10072199", "reaction_10072606", "reaction_10072720", "reaction_10072677", "reaction_10072715", "reaction_10072685", "reaction_10072154", "reaction_10072081", "reaction_10072713" ] }, "R-BTA-9034793": { "id": "pathway_10094966", "reactome": "R-BTA-9034793", "name": "Activated NTRK3 signals through PLCG1", "reactions": [ "reaction_10090675" ] }, "R-BTA-1483249": { "id": "pathway_10094168", "reactome": "R-BTA-1483249", "name": "Inositol phosphate metabolism", "reactions": [ "reaction_10061067", "reaction_10061128", "reaction_10061137", "reaction_10063020", "reaction_10060917", "reaction_10063018", "reaction_10061034", "reaction_10061017", "reaction_10061134", "reaction_10061031", "reaction_10060938", "reaction_10060986", "reaction_10061011", "reaction_10061043", "reaction_10061079", "reaction_10061076", "reaction_10061040", "reaction_10061131", "reaction_10061046", "reaction_10060963", "reaction_10061061", "reaction_10060980", "reaction_10061014", "reaction_10061122", "reaction_10061113", "reaction_10061024", "reaction_10060983", "reaction_10061052", "reaction_10061119", "reaction_10061006", "reaction_10061116", "reaction_10060956", "reaction_10061084", "reaction_10061049", "reaction_10061064", "reaction_10061125", "reaction_10060951", "reaction_10060993", "reaction_10061037" ] }, "R-BTA-9007892": { "id": "pathway_10094878", "reactome": "R-BTA-9007892", "name": "Interleukin-38 signaling", "reactions": [ "reaction_10089595", "reaction_10089597", "reaction_10089591" ] }, "R-BTA-983231": { "id": "pathway_10093948", "reactome": "R-BTA-983231", "name": "Factors involved in megakaryocyte development and platelet production", "reactions": [ "reaction_10055515", "reaction_10055920", "reaction_10055829", "reaction_10055870", "reaction_10055649", "reaction_10055647", "reaction_10055645", "reaction_10055995", "reaction_10055831", "reaction_10055827", "reaction_10055933", "reaction_10055847", "reaction_10056002", "reaction_10055823", "reaction_10055529", "reaction_10055833" ] }, "R-BTA-5689896": { "id": "pathway_10094620", "reactome": "R-BTA-5689896", "name": "Ovarian tumor domain proteases", "reactions": [ "reaction_10077406", "reaction_10075984", "reaction_10075989", "reaction_10075970", "reaction_10085345", "reaction_10084931", "reaction_10076001", "reaction_10075952" ] }, "R-BTA-72086": { "id": "pathway_10092700", "reactome": "R-BTA-72086", "name": "mRNA Capping", "reactions": [ "reaction_10036003" ] }, "R-BTA-983169": { "id": "pathway_10093380", "reactome": "R-BTA-983169", "name": "Class I MHC mediated antigen processing & presentation", "reactions": [ "reaction_10055783", "reaction_10055491", "reaction_10056835", "reaction_10084867", "reaction_10055821", "reaction_10087823", "reaction_10087807", "reaction_10057004", "reaction_10054866", "reaction_10056912", "reaction_10055448", "reaction_10055451", "reaction_10056910", "reaction_10056982", "reaction_10056914", "reaction_10056903", "reaction_10055431", "reaction_10055453", "reaction_10055817", "reaction_10056805", "reaction_10055444", "reaction_10084865", "reaction_10055819", "reaction_10055460", "reaction_10043659" ] }, "R-BTA-4641258": { "id": "pathway_10094404", "reactome": "R-BTA-4641258", "name": "Degradation of DVL", "reactions": [ "reaction_10069607" ] }, "R-BTA-69620": { "id": "pathway_10092450", "reactome": "R-BTA-69620", "name": "Cell Cycle Checkpoints", "reactions": [ "reaction_10081470", "reaction_10084051", "reaction_10033535", "reaction_10076341", "reaction_10084047", "reaction_10038033", "reaction_10038035", "reaction_10074692", "reaction_10078408", "reaction_10074695", "reaction_10040059" ] }, "R-BTA-8848584": { "id": "pathway_10093600", "reactome": "R-BTA-8848584", "name": "Wax and plasmalogen biosynthesis", "reactions": [ "reaction_10047065", "reaction_10077001", "reaction_10083575", "reaction_10083577" ] }, "R-BTA-111367": { "id": "pathway_10092768", "reactome": "R-BTA-111367", "name": "SLBP independent Processing of Histone Pre-mRNAs", "reactions": [ "reaction_10036915", "reaction_10036917" ] }, "R-BTA-74751": { "id": "pathway_10092642", "reactome": "R-BTA-74751", "name": "Insulin receptor signalling cascade", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10035536", "reaction_10036570", "reaction_10075097", "reaction_10035507", "reaction_10036607", "reaction_10036616", "reaction_10075065" ] }, "R-BTA-1638074": { "id": "pathway_10093852", "reactome": "R-BTA-1638074", "name": "Keratan sulfate/keratin metabolism", "reactions": [ "reaction_10063530", "reaction_10063485", "reaction_10063520", "reaction_10063232", "reaction_10063249", "reaction_10063510", "reaction_10063508", "reaction_10091293", "reaction_10060293", "reaction_10060285", "reaction_10063532", "reaction_10063477", "reaction_10051589", "reaction_10060295" ] }, "R-BTA-881907": { "id": "pathway_10093308", "reactome": "R-BTA-881907", "name": "Gastrin-CREB signalling pathway via PKC and MAPK", "reactions": [ "reaction_10064919", "reaction_10064915", "reaction_10064910", "reaction_10041950" ] }, "R-BTA-2871809": { "id": "pathway_10094316", "reactome": "R-BTA-2871809", "name": "FCERI mediated Ca+2 mobilization", "reactions": [ "reaction_10066052", "reaction_10066102", "reaction_10066094" ] }, "R-BTA-198725": { "id": "pathway_10093306", "reactome": "R-BTA-198725", "name": "Nuclear Events (kinase and transcription factor activation)", "reactions": [ "reaction_10042826", "reaction_10090994", "reaction_10043488", "reaction_10041950" ] }, "R-BTA-6804759": { "id": "pathway_10094340", "reactome": "R-BTA-6804759", "name": "Regulation of TP53 Activity through Association with Co-factors", "reactions": [ "reaction_10081470", "reaction_10081522", "reaction_10081530", "reaction_10080797", "reaction_10081889", "reaction_10080811", "reaction_10066764" ] }, "R-BTA-5693565": { "id": "pathway_10094582", "reactome": "R-BTA-5693565", "name": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks", "reactions": [ "reaction_10074695", "reaction_10076329", "reaction_10076334", "reaction_10075173", "reaction_10074550", "reaction_10076341", "reaction_10074670", "reaction_10074739", "reaction_10074747", "reaction_10074677", "reaction_10074558", "reaction_10076293", "reaction_10074679", "reaction_10074692", "reaction_10076303", "reaction_10074736", "reaction_10074720", "reaction_10076332" ] }, "R-BTA-109606": { "id": "pathway_10092818", "reactome": "R-BTA-109606", "name": "Intrinsic Pathway for Apoptosis", "reactions": [ "reaction_10037731", "reaction_10051175", "reaction_10037678", "reaction_10037706", "reaction_10037618", "reaction_10037253", "reaction_10091191", "reaction_10037723", "reaction_10037702", "reaction_10037277", "reaction_10091197", "reaction_10037293", "reaction_10081897", "reaction_10038007", "reaction_10037630", "reaction_10091186", "reaction_10091188", "reaction_10051181", "reaction_10037739", "reaction_10037237", "reaction_10037674", "reaction_10039520", "reaction_10037289", "reaction_10037264", "reaction_10037727", "reaction_10037622", "reaction_10037641" ] }, "R-BTA-9614399": { "id": "pathway_10094982", "reactome": "R-BTA-9614399", "name": "Regulation of localization of FOXO transcription factors", "reactions": [ "reaction_10091033", "reaction_10091023", "reaction_10091029", "reaction_10091017" ] }, "R-BTA-425381": { "id": "pathway_10093700", "reactome": "R-BTA-425381", "name": "Bicarbonate transporters", "reactions": [ "reaction_10048478", "reaction_10048491" ] }, "R-BTA-1257604": { "id": "pathway_10094150", "reactome": "R-BTA-1257604", "name": "PIP3 activates AKT signaling", "reactions": [ "reaction_10060556", "reaction_10065227", "reaction_10060448", "reaction_10065099", "reaction_10087531" ] }, "R-BTA-5658623": { "id": "pathway_10094534", "reactome": "R-BTA-5658623", "name": "FGFRL1 modulation of FGFR1 signaling", "reactions": [ "reaction_10073071", "reaction_10073077" ] }, "R-BTA-211981": { "id": "pathway_10092690", "reactome": "R-BTA-211981", "name": "Xenobiotics", "reactions": [ "reaction_10044477", "reaction_10044265", "reaction_10044182", "reaction_10035911", "reaction_10044167", "reaction_10035878", "reaction_10044223", "reaction_10044280", "reaction_10044250", "reaction_10044275", "reaction_10044204", "reaction_10035861", "reaction_10035977", "reaction_10035865", "reaction_10044218", "reaction_10044270" ] }, "R-BTA-193993": { "id": "pathway_10093246", "reactome": "R-BTA-193993", "name": "Mineralocorticoid biosynthesis", "reactions": [ "reaction_10041386", "reaction_10041397", "reaction_10041719", "reaction_10041269", "reaction_10041415", "reaction_10041393" ] }, "R-BTA-2151201": { "id": "pathway_10094608", "reactome": "R-BTA-2151201", "name": "Transcriptional activation of mitochondrial biogenesis", "reactions": [ "reaction_10075362", "reaction_10075350" ] }, "R-BTA-9031628": { "id": "pathway_10094978", "reactome": "R-BTA-9031628", "name": "NGF-stimulated transcription", "reactions": [ "reaction_10090994" ] }, "R-BTA-210990": { "id": "pathway_10093420", "reactome": "R-BTA-210990", "name": "PECAM1 interactions", "reactions": [ "reaction_10044024", "reaction_10044018", "reaction_10044034", "reaction_10044030", "reaction_10044039", "reaction_10044043" ] }, "R-BTA-77288": { "id": "pathway_10092724", "reactome": "R-BTA-77288", "name": "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids", "reactions": [ "reaction_10036220", "reaction_10036664", "reaction_10036218" ] }, "R-BTA-2024101": { "id": "pathway_10094122", "reactome": "R-BTA-2024101", "name": "CS/DS degradation", "reactions": [ "reaction_10060842", "reaction_10060031", "reaction_10091289", "reaction_10060829", "reaction_10062655", "reaction_10060825", "reaction_10063807", "reaction_10060827" ] }, "R-BTA-1614635": { "id": "pathway_10094008", "reactome": "R-BTA-1614635", "name": "Sulfur amino acid metabolism", "reactions": [ "reaction_10060361", "reaction_10060216", "reaction_10060275", "reaction_10057023", "reaction_10060255", "reaction_10060228", "reaction_10089959", "reaction_10060250", "reaction_10060264", "reaction_10089850", "reaction_10060218", "reaction_10060234", "reaction_10057032", "reaction_10077124", "reaction_10060207", "reaction_10057684", "reaction_10060252", "reaction_10090013", "reaction_10090015", "reaction_10090671", "reaction_10060231", "reaction_10083204", "reaction_10090679", "reaction_10090681" ] }, "R-BTA-380615": { "id": "pathway_10092884", "reactome": "R-BTA-380615", "name": "Serotonin clearance from the synaptic cleft", "reactions": [ "reaction_10046552", "reaction_10038000" ] }, "R-BTA-156580": { "id": "pathway_10092696", "reactome": "R-BTA-156580", "name": "Phase II - Conjugation of compounds", "reactions": [ "reaction_10040147", "reaction_10039887", "reaction_10038371", "reaction_10038318", "reaction_10077658", "reaction_10039874", "reaction_10038338", "reaction_10035863", "reaction_10038231", "reaction_10040136", "reaction_10040129", "reaction_10039749", "reaction_10039890", "reaction_10076900", "reaction_10048727", "reaction_10040131", "reaction_10040030", "reaction_10076898", "reaction_10040122", "reaction_10057079", "reaction_10040157", "reaction_10039865", "reaction_10040112", "reaction_10071924", "reaction_10038382", "reaction_10076799", "reaction_10038380", "reaction_10040115", "reaction_10039918", "reaction_10038238", "reaction_10087515", "reaction_10040120", "reaction_10038320", "reaction_10038340", "reaction_10039921", "reaction_10038354", "reaction_10040152", "reaction_10040107", "reaction_10039930", "reaction_10040098", "reaction_10051570", "reaction_10088617", "reaction_10038336", "reaction_10040021", "reaction_10040117", "reaction_10067425", "reaction_10039916", "reaction_10076785", "reaction_10039923", "reaction_10076133", "reaction_10088580", "reaction_10076903", "reaction_10038316", "reaction_10040185" ] }, "R-BTA-425366": { "id": "pathway_10093480", "reactome": "R-BTA-425366", "name": "Transport of bile salts and organic acids, metal ions and amine compounds", "reactions": [ "reaction_10049402", "reaction_10049333", "reaction_10051314", "reaction_10051307", "reaction_10049090", "reaction_10049464", "reaction_10049583", "reaction_10049635", "reaction_10049371", "reaction_10049440", "reaction_10051325", "reaction_10049358", "reaction_10049326", "reaction_10045487", "reaction_10051269", "reaction_10049871", "reaction_10049628", "reaction_10049447", "reaction_10049433", "reaction_10049319", "reaction_10049378", "reaction_10049869", "reaction_10045419", "reaction_10044941", "reaction_10049060", "reaction_10049613", "reaction_10051276", "reaction_10049592", "reaction_10045480", "reaction_10049606", "reaction_10051305", "reaction_10049599", "reaction_10049392", "reaction_10044934", "reaction_10049078", "reaction_10051283", "reaction_10049385", "reaction_10088912", "reaction_10051286", "reaction_10044948" ] }, "R-BTA-450321": { "id": "pathway_10093800", "reactome": "R-BTA-450321", "name": "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1", "reactions": [ "reaction_10050256" ] }, "R-BTA-426048": { "id": "pathway_10093708", "reactome": "R-BTA-426048", "name": "Arachidonate production from DAG", "reactions": [ "reaction_10048587", "reaction_10076743", "reaction_10048580" ] }, "R-BTA-429958": { "id": "pathway_10093740", "reactome": "R-BTA-429958", "name": "mRNA decay by 3' to 5' exoribonuclease", "reactions": [ "reaction_10049230" ] }, "R-BTA-446353": { "id": "pathway_10093752", "reactome": "R-BTA-446353", "name": "Cell-extracellular matrix interactions", "reactions": [ "reaction_10049891", "reaction_10049312", "reaction_10049883" ] }, "R-BTA-8941858": { "id": "pathway_10094788", "reactome": "R-BTA-8941858", "name": "Regulation of RUNX3 expression and activity", "reactions": [ "reaction_10086587", "reaction_10086581", "reaction_10088490", "reaction_10088482", "reaction_10084947", "reaction_10086589" ] }, "R-BTA-1059683": { "id": "pathway_10093960", "reactome": "R-BTA-1059683", "name": "Interleukin-6 signaling", "reactions": [ "reaction_10056207", "reaction_10056201", "reaction_10056127", "reaction_10056130", "reaction_10056188", "reaction_10056123", "reaction_10056178", "reaction_10056205", "reaction_10056199", "reaction_10056170", "reaction_10056194", "reaction_10056110", "reaction_10056176", "reaction_10056172", "reaction_10056168", "reaction_10056132", "reaction_10056185", "reaction_10056102", "reaction_10091747" ] }, "R-BTA-193807": { "id": "pathway_10093234", "reactome": "R-BTA-193807", "name": "Synthesis of bile acids and bile salts via 27-hydroxycholesterol", "reactions": [ "reaction_10041377", "reaction_10041097", "reaction_10041371", "reaction_10041375", "reaction_10041206", "reaction_10041373", "reaction_10041369" ] }, "R-BTA-556833": { "id": "pathway_10092528", "reactome": "R-BTA-556833", "name": "Metabolism of lipids", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10082880", "reaction_10041363", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10041359", "reaction_10071388", "reaction_10083575", "reaction_10060569", "reaction_10082934", "reaction_10058998", "reaction_10059977", "reaction_10036029", "reaction_10063444", "reaction_10060302", "reaction_10044657", "reaction_10063560", "reaction_10071344", "reaction_10041477", "reaction_10060448", "reaction_10064442", "reaction_10041500", "reaction_10047807", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10082152", "reaction_10085784", "reaction_10047001", "reaction_10076792", "reaction_10041357", "reaction_10047058", "reaction_10036021", "reaction_10064465", "reaction_10041415", "reaction_10033896", "reaction_10041310", "reaction_10059006", "reaction_10041290", "reaction_10064452", "reaction_10040895", "reaction_10041327", "reaction_10086403", "reaction_10085843", "reaction_10084480", "reaction_10041664", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10064546", "reaction_10082058", "reaction_10088928", "reaction_10085316", "reaction_10035417", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10041349", "reaction_10064474", "reaction_10060553", "reaction_10037748", "reaction_10090390", "reaction_10036042", "reaction_10041493", "reaction_10046989", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10041204", "reaction_10085775", "reaction_10047056", "reaction_10041301", "reaction_10041299", "reaction_10048882", "reaction_10041195", "reaction_10090468", "reaction_10076806", "reaction_10090394", "reaction_10041208", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10085291", "reaction_10058812", "reaction_10084424", "reaction_10040933", "reaction_10041424", "reaction_10064503", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10047065", "reaction_10059016", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10075631", "reaction_10041317", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10040922", "reaction_10060461", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10064516", "reaction_10058894", "reaction_10036220", "reaction_10060041", "reaction_10060614", "reaction_10084694", "reaction_10046992", "reaction_10041323", "reaction_10035786", "reaction_10086336", "reaction_10060600", "reaction_10049004", "reaction_10085798", "reaction_10060590", "reaction_10041437", "reaction_10041671", "reaction_10058916", "reaction_10041277", "reaction_10076281", "reaction_10060429", "reaction_10083369", "reaction_10059035", "reaction_10090379", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10049182", "reaction_10046984", "reaction_10090440", "reaction_10060572", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10040913", "reaction_10049163", "reaction_10048986", "reaction_10058908", "reaction_10041226", "reaction_10041341", "reaction_10035372", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10090460", "reaction_10041111", "reaction_10041170", "reaction_10063420", "reaction_10060476", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10047042", "reaction_10064479", "reaction_10059114", "reaction_10058892", "reaction_10049154", "reaction_10058945", "reaction_10041716", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10059141", "reaction_10060468", "reaction_10044599", "reaction_10041484", "reaction_10059991", "reaction_10054592", "reaction_10092062", "reaction_10035795", "reaction_10041397", "reaction_10088026", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10036664", "reaction_10083800", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10041367", "reaction_10059094", "reaction_10064445", "reaction_10041369", "reaction_10058943", "reaction_10033889", "reaction_10080887", "reaction_10059026", "reaction_10041365", "reaction_10059853", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10064534", "reaction_10040892", "reaction_10092065", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10090382", "reaction_10051261", "reaction_10041353", "reaction_10063456", "reaction_10059851", "reaction_10077004", "reaction_10051676", "reaction_10035812", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10058993", "reaction_10083577", "reaction_10036038", "reaction_10058913", "reaction_10085808", "reaction_10063430", "reaction_10063442", "reaction_10059984", "reaction_10059856", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10041319", "reaction_10041179", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10083211", "reaction_10064491", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10041377", "reaction_10065225", "reaction_10042961", "reaction_10041172", "reaction_10041486", "reaction_10058834", "reaction_10043885", "reaction_10058874", "reaction_10041386", "reaction_10059858", "reaction_10040881", "reaction_10060109", "reaction_10033912", "reaction_10058896", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10041193", "reaction_10090498", "reaction_10090510", "reaction_10048978", "reaction_10060498", "reaction_10041293", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10074353", "reaction_10090384", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10041412", "reaction_10083389", "reaction_10063564", "reaction_10085780", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10090489", "reaction_10059000", "reaction_10064578", "reaction_10059951", "reaction_10058910", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10060556", "reaction_10063413", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10086064", "reaction_10063437", "reaction_10036012", "reaction_10090464", "reaction_10088926", "reaction_10060550", "reaction_10041197", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10064581", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10090474", "reaction_10043984", "reaction_10063448", "reaction_10060021", "reaction_10077777", "reaction_10041297", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10058880", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10083547", "reaction_10041284", "reaction_10060597", "reaction_10090508", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10041321", "reaction_10090504", "reaction_10090392", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10084526", "reaction_10063428", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10044739", "reaction_10041721", "reaction_10060518", "reaction_10085340", "reaction_10043971", "reaction_10058809", "reaction_10085185", "reaction_10041347", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10041373", "reaction_10060535", "reaction_10063440", "reaction_10035838", "reaction_10059014", "reaction_10082136", "reaction_10043910", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10077835", "reaction_10047044", "reaction_10065223", "reaction_10058923", "reaction_10049161", "reaction_10085024", "reaction_10041379", "reaction_10060012", "reaction_10090386", "reaction_10058877", "reaction_10083092", "reaction_10086248", "reaction_10059121", "reaction_10040924", "reaction_10041502", "reaction_10058980", "reaction_10047033", "reaction_10058990", "reaction_10085806", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10048995", "reaction_10059860", "reaction_10059961", "reaction_10049116", "reaction_10060316", "reaction_10077001", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10088019", "reaction_10041335", "reaction_10064511", "reaction_10043964", "reaction_10082889", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10041217", "reaction_10059150", "reaction_10091936" ] }, "R-BTA-948021": { "id": "pathway_10093376", "reactome": "R-BTA-948021", "name": "Transport to the Golgi and subsequent modification", "reactions": [ "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10077710", "reaction_10053317", "reaction_10076708", "reaction_10076610", "reaction_10054467", "reaction_10054474", "reaction_10076584", "reaction_10053324", "reaction_10054418", "reaction_10076696", "reaction_10076635", "reaction_10076736", "reaction_10054438", "reaction_10076586", "reaction_10076706", "reaction_10053337", "reaction_10056061", "reaction_10056074", "reaction_10077717", "reaction_10082026", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10053339", "reaction_10076422", "reaction_10054411", "reaction_10076415", "reaction_10083380", "reaction_10054431", "reaction_10076778", "reaction_10053331", "reaction_10076698" ] }, "R-BTA-6794362": { "id": "pathway_10093578", "reactome": "R-BTA-6794362", "name": "Protein-protein interactions at synapses", "reactions": [ "reaction_10078674", "reaction_10078488", "reaction_10078566", "reaction_10084356", "reaction_10083793", "reaction_10046868", "reaction_10078522", "reaction_10078446", "reaction_10078682", "reaction_10078518", "reaction_10083789", "reaction_10078600", "reaction_10078464", "reaction_10078466" ] }, "R-BTA-4641265": { "id": "pathway_10094408", "reactome": "R-BTA-4641265", "name": "Repression of WNT target genes", "reactions": [ "reaction_10071356", "reaction_10087597", "reaction_10069651" ] }, "R-BTA-917937": { "id": "pathway_10093166", "reactome": "R-BTA-917937", "name": "Iron uptake and transport", "reactions": [ "reaction_10052907", "reaction_10052914", "reaction_10076099", "reaction_10049371", "reaction_10052916", "reaction_10052901", "reaction_10076083", "reaction_10052888", "reaction_10059181", "reaction_10040636", "reaction_10076091", "reaction_10052925", "reaction_10052909", "reaction_10070906", "reaction_10052911", "reaction_10052866", "reaction_10052923" ] }, "R-BTA-5358493": { "id": "pathway_10094448", "reactome": "R-BTA-5358493", "name": "Synthesis of diphthamide-EEF2", "reactions": [ "reaction_10071566", "reaction_10071579" ] }, "R-BTA-446199": { "id": "pathway_10093220", "reactome": "R-BTA-446199", "name": "Synthesis of Dolichyl-phosphate", "reactions": [ "reaction_10049804", "reaction_10069498", "reaction_10049818", "reaction_10040933" ] }, "R-BTA-140877": { "id": "pathway_10092874", "reactome": "R-BTA-140877", "name": "Formation of Fibrin Clot (Clotting Cascade)", "reactions": [ "reaction_10037913", "reaction_10037906", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10090718", "reaction_10071946", "reaction_10090183", "reaction_10037923", "reaction_10037948", "reaction_10090181", "reaction_10037845", "reaction_10038205", "reaction_10037800", "reaction_10037937", "reaction_10090185", "reaction_10037927", "reaction_10037899", "reaction_10038201", "reaction_10037887", "reaction_10037915", "reaction_10037852", "reaction_10091671", "reaction_10038221", "reaction_10038213", "reaction_10037950", "reaction_10037815", "reaction_10091546", "reaction_10038166", "reaction_10071906", "reaction_10037895" ] }, "R-BTA-1474165": { "id": "pathway_10094050", "reactome": "R-BTA-1474165", "name": "Reproduction", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10057605", "reaction_10057598", "reaction_10065827", "reaction_10065866" ] }, "R-BTA-9033241": { "id": "pathway_10094954", "reactome": "R-BTA-9033241", "name": "Peroxisomal protein import", "reactions": [ "reaction_10090604", "reaction_10090593" ] }, "R-BTA-71064": { "id": "pathway_10092512", "reactome": "R-BTA-71064", "name": "Lysine catabolism", "reactions": [ "reaction_10045036", "reaction_10051198", "reaction_10077435", "reaction_10077864", "reaction_10076984", "reaction_10076261" ] }, "R-BTA-375165": { "id": "pathway_10093636", "reactome": "R-BTA-375165", "name": "NCAM signaling for neurite out-growth", "reactions": [ "reaction_10047449", "reaction_10047455", "reaction_10047458" ] }, "R-BTA-8866907": { "id": "pathway_10094782", "reactome": "R-BTA-8866907", "name": "Activation of the TFAP2 (AP-2) family of transcription factors", "reactions": [ "reaction_10084911", "reaction_10084922", "reaction_10084895", "reaction_10084881" ] }, "R-BTA-5620924": { "id": "pathway_10094482", "reactome": "R-BTA-5620924", "name": "Intraflagellar transport", "reactions": [ "reaction_10072271" ] }, "R-BTA-165159": { "id": "pathway_10092996", "reactome": "R-BTA-165159", "name": "MTOR signalling", "reactions": [ "reaction_10073851", "reaction_10049894", "reaction_10039200", "reaction_10046588", "reaction_10046572", "reaction_10091741", "reaction_10073853", "reaction_10088496", "reaction_10072902", "reaction_10072900", "reaction_10039127", "reaction_10039155", "reaction_10088493", "reaction_10039059", "reaction_10046583", "reaction_10039209", "reaction_10073844", "reaction_10039160", "reaction_10039180" ] }, "R-BTA-9607240": { "id": "pathway_10094646", "reactome": "R-BTA-9607240", "name": "FLT3 Signaling", "reactions": [ "reaction_10092147", "reaction_10092173", "reaction_10092033", "reaction_10092139", "reaction_10092165", "reaction_10092126", "reaction_10077790", "reaction_10090916", "reaction_10092143", "reaction_10092195", "reaction_10092159", "reaction_10090919", "reaction_10090844", "reaction_10092141", "reaction_10092043", "reaction_10084305", "reaction_10092137", "reaction_10092183", "reaction_10092040", "reaction_10092151", "reaction_10092133" ] }, "R-BTA-977347": { "id": "pathway_10093940", "reactome": "R-BTA-977347", "name": "Serine biosynthesis", "reactions": [ "reaction_10090647", "reaction_10054601", "reaction_10086371", "reaction_10090175", "reaction_10054620", "reaction_10054611", "reaction_10090172" ] }, "R-BTA-196819": { "id": "pathway_10093286", "reactome": "R-BTA-196819", "name": "Vitamin B1 (thiamin) metabolism", "reactions": [ "reaction_10041753", "reaction_10042799" ] }, "R-BTA-111446": { "id": "pathway_10092862", "reactome": "R-BTA-111446", "name": "Activation of BIM and translocation to mitochondria ", "reactions": [ "reaction_10037723", "reaction_10037727" ] }, "R-BTA-74158": { "id": "pathway_10092686", "reactome": "R-BTA-74158", "name": "RNA Polymerase III Transcription", "reactions": [ "reaction_10035854" ] }, "R-BTA-170968": { "id": "pathway_10093102", "reactome": "R-BTA-170968", "name": "Frs2-mediated activation", "reactions": [ "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090944", "reaction_10090954", "reaction_10039711" ] }, "R-BTA-2142850": { "id": "pathway_10094226", "reactome": "R-BTA-2142850", "name": "Hyaluronan biosynthesis and export", "reactions": [ "reaction_10064353" ] }, "R-BTA-75876": { "id": "pathway_10093330", "reactome": "R-BTA-75876", "name": "Synthesis of very long-chain fatty acyl-CoAs", "reactions": [ "reaction_10051252", "reaction_10042961", "reaction_10074353", "reaction_10051261" ] }, "R-BTA-2871837": { "id": "pathway_10093354", "reactome": "R-BTA-2871837", "name": "FCERI mediated NF-kB activation", "reactions": [ "reaction_10066059", "reaction_10066172", "reaction_10066141", "reaction_10066127", "reaction_10066147", "reaction_10043225", "reaction_10066180", "reaction_10066168" ] }, "R-BTA-8956321": { "id": "pathway_10092596", "reactome": "R-BTA-8956321", "name": "Nucleotide salvage", "reactions": [ "reaction_10036306", "reaction_10088624", "reaction_10035435", "reaction_10035426", "reaction_10035020", "reaction_10036308", "reaction_10034989", "reaction_10036649", "reaction_10034980", "reaction_10051215", "reaction_10035444", "reaction_10035479", "reaction_10035007", "reaction_10036614", "reaction_10036001" ] }, "R-BTA-210500": { "id": "pathway_10092502", "reactome": "R-BTA-210500", "name": "Glutamate Neurotransmitter Release Cycle", "reactions": [ "reaction_10044076", "reaction_10044461", "reaction_10033755" ] }, "R-BTA-112043": { "id": "pathway_10092770", "reactome": "R-BTA-112043", "name": "PLC beta mediated events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10037045", "reaction_10049478", "reaction_10036959", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-6798695": { "id": "pathway_10094666", "reactome": "R-BTA-6798695", "name": "Neutrophil degranulation", "reactions": [ "reaction_10080063", "reaction_10078929", "reaction_10080435", "reaction_10079391", "reaction_10080719", "reaction_10079949", "reaction_10079653", "reaction_10079199", "reaction_10081085", "reaction_10081265" ] }, "R-BTA-190371": { "id": "pathway_10093194", "reactome": "R-BTA-190371", "name": "FGFR3b ligand binding and activation", "reactions": [ "reaction_10040761", "reaction_10040779" ] }, "R-BTA-191859": { "id": "pathway_10093230", "reactome": "R-BTA-191859", "name": "snRNP Assembly", "reactions": [ "reaction_10041050", "reaction_10041039" ] }, "R-BTA-173599": { "id": "pathway_10093108", "reactome": "R-BTA-173599", "name": "Formation of the active cofactor, UDP-glucuronate", "reactions": [ "reaction_10039874", "reaction_10039749" ] }, "R-BTA-1660514": { "id": "pathway_10094156", "reactome": "R-BTA-1660514", "name": "Synthesis of PIPs at the Golgi membrane", "reactions": [ "reaction_10060597", "reaction_10060483", "reaction_10060516", "reaction_10060611", "reaction_10060498" ] }, "R-BTA-168643": { "id": "pathway_10093868", "reactome": "R-BTA-168643", "name": "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways", "reactions": [ "reaction_10051836" ] }, "R-BTA-75944": { "id": "pathway_10092976", "reactome": "R-BTA-75944", "name": "Transcription from mitochondrial promoters", "reactions": [ "reaction_10038904" ] }, "R-BTA-69473": { "id": "pathway_10094586", "reactome": "R-BTA-69473", "name": "G2/M DNA damage checkpoint", "reactions": [ "reaction_10074695", "reaction_10074692" ] }, "R-BTA-416700": { "id": "pathway_10093510", "reactome": "R-BTA-416700", "name": "Other semaphorin interactions", "reactions": [ "reaction_10045244", "reaction_10045236" ] }, "R-BTA-933541": { "id": "pathway_10093900", "reactome": "R-BTA-933541", "name": "TRAF6 mediated IRF7 activation", "reactions": [ "reaction_10056088", "reaction_10053048", "reaction_10053046", "reaction_10053058" ] }, "R-BTA-388479": { "id": "pathway_10093566", "reactome": "R-BTA-388479", "name": "Vasopressin-like receptors", "reactions": [ "reaction_10046733", "reaction_10046731", "reaction_10047483" ] }, "R-BTA-2980736": { "id": "pathway_10093532", "reactome": "R-BTA-2980736", "name": "Peptide hormone metabolism", "reactions": [ "reaction_10045736", "reaction_10046723", "reaction_10091056", "reaction_10048461", "reaction_10048429", "reaction_10049392", "reaction_10045744", "reaction_10045696", "reaction_10048380", "reaction_10049385", "reaction_10048407", "reaction_10048465", "reaction_10045694" ] }, "R-BTA-75955": { "id": "pathway_10092814", "reactome": "R-BTA-75955", "name": "RNA Polymerase II Transcription Elongation", "reactions": [ "reaction_10037205", "reaction_10037203" ] }, "R-BTA-71288": { "id": "pathway_10092544", "reactome": "R-BTA-71288", "name": "Creatine metabolism", "reactions": [ "reaction_10033997", "reaction_10042838", "reaction_10042847", "reaction_10034004" ] }, "R-BTA-450531": { "id": "pathway_10093804", "reactome": "R-BTA-450531", "name": "Regulation of mRNA stability by proteins that bind AU-rich elements", "reactions": [ "reaction_10050380", "reaction_10050373", "reaction_10051066", "reaction_10050306", "reaction_10051219", "reaction_10050378", "reaction_10051221", "reaction_10050366", "reaction_10050342", "reaction_10050408", "reaction_10050368", "reaction_10050318", "reaction_10050400" ] }, "R-BTA-5140745": { "id": "pathway_10094414", "reactome": "R-BTA-5140745", "name": "WNT5A-dependent internalization of FZD2, FZD5 and ROR2", "reactions": [ "reaction_10069896" ] }, "R-BTA-69202": { "id": "pathway_10093150", "reactome": "R-BTA-69202", "name": "Cyclin E associated events during G1/S transition ", "reactions": [ "reaction_10040521", "reaction_10083565", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-5610787": { "id": "pathway_10094474", "reactome": "R-BTA-5610787", "name": "Hedgehog 'off' state", "reactions": [ "reaction_10072138", "reaction_10072220", "reaction_10072123", "reaction_10072199", "reaction_10072154", "reaction_10072081" ] }, "R-BTA-8963899": { "id": "pathway_10093458", "reactome": "R-BTA-8963899", "name": "Plasma lipoprotein remodeling", "reactions": [ "reaction_10044547", "reaction_10084509", "reaction_10077487", "reaction_10077489", "reaction_10088982", "reaction_10044666" ] }, "R-BTA-69206": { "id": "pathway_10092408", "reactome": "R-BTA-69206", "name": "G1/S Transition", "reactions": [ "reaction_10033512", "reaction_10040521", "reaction_10083565", "reaction_10033466", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-74217": { "id": "pathway_10092634", "reactome": "R-BTA-74217", "name": "Purine salvage", "reactions": [ "reaction_10036306", "reaction_10035435", "reaction_10035426", "reaction_10036308", "reaction_10051215", "reaction_10035444", "reaction_10036001" ] }, "R-BTA-1236973": { "id": "pathway_10094000", "reactome": "R-BTA-1236973", "name": "Cross-presentation of particulate exogenous antigens (phagosomes)", "reactions": [ "reaction_10057004" ] }, "R-BTA-204626": { "id": "pathway_10093390", "reactome": "R-BTA-204626", "name": "Hypusine synthesis from eIF5A-lysine", "reactions": [ "reaction_10043717", "reaction_10043698" ] }, "R-BTA-422356": { "id": "pathway_10093464", "reactome": "R-BTA-422356", "name": "Regulation of insulin secretion", "reactions": [ "reaction_10047765", "reaction_10047809", "reaction_10046642", "reaction_10049346", "reaction_10046623", "reaction_10049351", "reaction_10044634", "reaction_10046630", "reaction_10046648" ] }, "R-BTA-5357801": { "id": "pathway_10092622", "reactome": "R-BTA-5357801", "name": "Programmed Cell Death", "reactions": [ "reaction_10037731", "reaction_10044146", "reaction_10068030", "reaction_10037678", "reaction_10037706", "reaction_10044756", "reaction_10091191", "reaction_10044869", "reaction_10037723", "reaction_10074240", "reaction_10038007", "reaction_10091409", "reaction_10091186", "reaction_10070684", "reaction_10072346", "reaction_10051181", "reaction_10037739", "reaction_10043021", "reaction_10091783", "reaction_10037727", "reaction_10037985", "reaction_10037622", "reaction_10092356", "reaction_10044568", "reaction_10051175", "reaction_10037253", "reaction_10037702", "reaction_10037277", "reaction_10067891", "reaction_10091793", "reaction_10044680", "reaction_10071534", "reaction_10091808", "reaction_10090573", "reaction_10091810", "reaction_10037289", "reaction_10091429", "reaction_10070531", "reaction_10091415", "reaction_10044906", "reaction_10037641", "reaction_10092350", "reaction_10068042", "reaction_10037991", "reaction_10043039", "reaction_10037618", "reaction_10070534", "reaction_10044762", "reaction_10068046", "reaction_10044896", "reaction_10044927", "reaction_10035396", "reaction_10037293", "reaction_10091197", "reaction_10037630", "reaction_10091188", "reaction_10092358", "reaction_10043059", "reaction_10081905", "reaction_10037674", "reaction_10039520", "reaction_10070682", "reaction_10092341", "reaction_10070689", "reaction_10090575", "reaction_10037264", "reaction_10092352", "reaction_10091423", "reaction_10092354", "reaction_10091773", "reaction_10044116", "reaction_10091439", "reaction_10043049", "reaction_10091806", "reaction_10044995", "reaction_10074254", "reaction_10044578", "reaction_10081897", "reaction_10091779", "reaction_10044142", "reaction_10037237", "reaction_10091425", "reaction_10044923", "reaction_10044144", "reaction_10067895" ] }, "R-BTA-1430728": { "id": "pathway_10092458", "reactome": "R-BTA-1430728", "name": "Metabolism", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10066450", "reaction_10080521", "reaction_10088624", "reaction_10060216", "reaction_10082880", "reaction_10036683", "reaction_10041363", "reaction_10066430", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10062697", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10090172", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10053352", "reaction_10090645", "reaction_10040136", "reaction_10041359", "reaction_10044250", "reaction_10071388", "reaction_10076900", "reaction_10083575", "reaction_10060569", "reaction_10036308", "reaction_10063807", "reaction_10082934", "reaction_10065378", "reaction_10058998", "reaction_10059977", "reaction_10038427", "reaction_10039254", "reaction_10036029", "reaction_10034224", "reaction_10041772", "reaction_10080515", "reaction_10050437", "reaction_10051185", "reaction_10063444", "reaction_10087515", "reaction_10039921", "reaction_10044657", "reaction_10060302", "reaction_10038354", "reaction_10063560", "reaction_10064353", "reaction_10052030", "reaction_10083876", "reaction_10061064", "reaction_10071344", "reaction_10044480", "reaction_10041477", "reaction_10060448", "reaction_10034998", "reaction_10064442", "reaction_10034962", "reaction_10041500", "reaction_10047807", "reaction_10036938", "reaction_10061395", "reaction_10076274", "reaction_10064346", "reaction_10039044", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10033620", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10080765", "reaction_10082152", "reaction_10061612", "reaction_10085784", "reaction_10039874", "reaction_10047001", "reaction_10044235", "reaction_10076792", "reaction_10078710", "reaction_10041357", "reaction_10082078", "reaction_10043956", "reaction_10047058", "reaction_10036021", "reaction_10044223", "reaction_10041415", "reaction_10064465", "reaction_10089808", "reaction_10033896", "reaction_10086272", "reaction_10090851", "reaction_10041310", "reaction_10060250", "reaction_10041790", "reaction_10038000", "reaction_10080519", "reaction_10077864", "reaction_10059006", "reaction_10039918", "reaction_10041290", "reaction_10064452", "reaction_10042847", "reaction_10040895", "reaction_10033962", "reaction_10041327", "reaction_10061116", "reaction_10090620", "reaction_10086403", "reaction_10046642", "reaction_10086371", "reaction_10034041", "reaction_10085843", "reaction_10084480", "reaction_10066526", "reaction_10063603", "reaction_10077890", "reaction_10076856", "reaction_10044293", "reaction_10041664", "reaction_10050160", "reaction_10041885", "reaction_10033718", "reaction_10040185", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10041753", "reaction_10034953", "reaction_10063520", "reaction_10060255", "reaction_10064546", "reaction_10083614", "reaction_10090703", "reaction_10082058", "reaction_10088666", "reaction_10088928", "reaction_10043948", "reaction_10091291", "reaction_10085316", "reaction_10035417", "reaction_10041838", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10063803", "reaction_10089721", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10060678", "reaction_10036207", "reaction_10041349", "reaction_10077458", "reaction_10064474", "reaction_10060825", "reaction_10033706", "reaction_10037748", "reaction_10076884", "reaction_10060553", "reaction_10090390", "reaction_10044265", "reaction_10060625", "reaction_10090647", "reaction_10033570", "reaction_10061061", "reaction_10060980", "reaction_10040157", "reaction_10040636", "reaction_10044247", "reaction_10036042", "reaction_10041493", "reaction_10038382", "reaction_10063805", "reaction_10033840", "reaction_10046989", "reaction_10044195", "reaction_10081935", "reaction_10052046", "reaction_10039930", "reaction_10063014", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10081339", "reaction_10041204", "reaction_10085775", "reaction_10044158", "reaction_10076475", "reaction_10047056", "reaction_10060993", "reaction_10062463", "reaction_10083852", "reaction_10077124", "reaction_10041301", "reaction_10066502", "reaction_10039916", "reaction_10076785", "reaction_10041299", "reaction_10076133", "reaction_10048882", "reaction_10035345", "reaction_10041195", "reaction_10090468", "reaction_10054375", "reaction_10041975", "reaction_10083204", "reaction_10044844", "reaction_10060361", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10038895", "reaction_10035464", "reaction_10060228", "reaction_10082068", "reaction_10076806", "reaction_10090394", "reaction_10033770", "reaction_10091727", "reaction_10041208", "reaction_10076485", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10060671", "reaction_10085291", "reaction_10065437", "reaction_10058812", "reaction_10044242", "reaction_10085362", "reaction_10049170", "reaction_10084424", "reaction_10089959", "reaction_10033594", "reaction_10036909", "reaction_10040933", "reaction_10041424", "reaction_10035878", "reaction_10058755", "reaction_10064503", "reaction_10040131", "reaction_10076441", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10033944", "reaction_10033690", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10036256", "reaction_10047065", "reaction_10067648", "reaction_10047019", "reaction_10059016", "reaction_10046630", "reaction_10035865", "reaction_10062655", "reaction_10060983", "reaction_10076254", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10051165", "reaction_10075631", "reaction_10041317", "reaction_10067644", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10035011", "reaction_10039923", "reaction_10040922", "reaction_10060461", "reaction_10089728", "reaction_10088580", "reaction_10090013", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10066528", "reaction_10060231", "reaction_10077453", "reaction_10064516", "reaction_10033849", "reaction_10076984", "reaction_10058894", "reaction_10036220", "reaction_10089795", "reaction_10060041", "reaction_10041962", "reaction_10051215", "reaction_10063018", "reaction_10060614", "reaction_10033778", "reaction_10084694", "reaction_10071722", "reaction_10085352", "reaction_10046992", "reaction_10036267", "reaction_10060986", "reaction_10050169", "reaction_10035863", "reaction_10041817", "reaction_10041323", "reaction_10038060", "reaction_10064393", "reaction_10035786", "reaction_10066416", "reaction_10086336", "reaction_10042940", "reaction_10071763", "reaction_10042799", "reaction_10067733", "reaction_10035911", "reaction_10060600", "reaction_10036258", "reaction_10049004", "reaction_10042915", "reaction_10085798", "reaction_10071909", "reaction_10060590", "reaction_10034013", "reaction_10039049", "reaction_10040115", "reaction_10041437", "reaction_10036692", "reaction_10041671", "reaction_10058916", "reaction_10061251", "reaction_10042657", "reaction_10045036", "reaction_10041277", "reaction_10044211", "reaction_10076281", "reaction_10033638", "reaction_10038336", "reaction_10060429", "reaction_10083369", "reaction_10041878", "reaction_10033788", "reaction_10086033", "reaction_10090015", "reaction_10059035", "reaction_10090379", "reaction_10036001", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10042929", "reaction_10086630", "reaction_10049182", "reaction_10058772", "reaction_10046984", "reaction_10051980", "reaction_10090440", "reaction_10060572", "reaction_10063020", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10063610", "reaction_10085365", "reaction_10065328", "reaction_10040913", "reaction_10049163", "reaction_10065319", "reaction_10054611", "reaction_10061134", "reaction_10077658", "reaction_10048986", "reaction_10045692", "reaction_10063010", "reaction_10036231", "reaction_10058908", "reaction_10035047", "reaction_10041226", "reaction_10061011", "reaction_10090493", "reaction_10041341", "reaction_10041840", "reaction_10040672", "reaction_10061076", "reaction_10035372", "reaction_10091605", "reaction_10066249", "reaction_10080747", "reaction_10060031", "reaction_10067610", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10061122", "reaction_10090460", "reaction_10069948", "reaction_10041111", "reaction_10041170", "reaction_10045043", "reaction_10041824", "reaction_10060264", "reaction_10063420", "reaction_10060476", "reaction_10060234", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10033997", "reaction_10034240", "reaction_10050446", "reaction_10043933", "reaction_10090638", "reaction_10034944", "reaction_10038938", "reaction_10047042", "reaction_10083861", "reaction_10064479", "reaction_10091286", "reaction_10059114", "reaction_10058892", "reaction_10065359", "reaction_10090162", "reaction_10049154", "reaction_10058524", "reaction_10058945", "reaction_10051973", "reaction_10067639", "reaction_10041716", "reaction_10036614", "reaction_10033737", "reaction_10058753", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10033611", "reaction_10033629", "reaction_10035435", "reaction_10059141", "reaction_10033824", "reaction_10060468", "reaction_10033697", "reaction_10033728", "reaction_10044599", "reaction_10091293", "reaction_10061131", "reaction_10041484", "reaction_10059991", "reaction_10085359", "reaction_10054592", "reaction_10066461", "reaction_10092062", "reaction_10035795", "reaction_10054585", "reaction_10041397", "reaction_10063232", "reaction_10088026", "reaction_10035426", "reaction_10086557", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10061052", "reaction_10053348", "reaction_10036664", "reaction_10083800", "reaction_10087455", "reaction_10042922", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10071715", "reaction_10041367", "reaction_10059094", "reaction_10088617", "reaction_10078575", "reaction_10033935", "reaction_10033833", "reaction_10054620", "reaction_10034238", "reaction_10043986", "reaction_10035861", "reaction_10034032", "reaction_10076863", "reaction_10065383", "reaction_10064445", "reaction_10044801", "reaction_10033969", "reaction_10041369", "reaction_10033579", "reaction_10061137", "reaction_10058943", "reaction_10033889", "reaction_10072825", "reaction_10061350", "reaction_10035455", "reaction_10061034", "reaction_10076375", "reaction_10052056", "reaction_10090802", "reaction_10086623", "reaction_10058785", "reaction_10090155", "reaction_10080887", "reaction_10059026", "reaction_10065445", "reaction_10061079", "reaction_10041365", "reaction_10061040", "reaction_10059853", "reaction_10041744", "reaction_10036649", "reaction_10035329", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10044524", "reaction_10064534", "reaction_10060842", "reaction_10060963", "reaction_10040892", "reaction_10092065", "reaction_10073431", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10049351", "reaction_10078393", "reaction_10042838", "reaction_10061113", "reaction_10034980", "reaction_10067622", "reaction_10040120", "reaction_10044218", "reaction_10090382", "reaction_10058774", "reaction_10066576", "reaction_10051261", "reaction_10041353", "reaction_10063530", "reaction_10090631", "reaction_10082143", "reaction_10036306", "reaction_10047765", "reaction_10063456", "reaction_10077444", "reaction_10059851", "reaction_10088867", "reaction_10076130", "reaction_10077435", "reaction_10071727", "reaction_10077004", "reaction_10042906", "reaction_10034140", "reaction_10061037", "reaction_10083115", "reaction_10051676", "reaction_10087442", "reaction_10061067", "reaction_10035812", "reaction_10066471", "reaction_10071712", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10038318", "reaction_10033592", "reaction_10035319", "reaction_10060938", "reaction_10034118", "reaction_10038338", "reaction_10044255", "reaction_10035009", "reaction_10076459", "reaction_10066571", "reaction_10088737", "reaction_10039047", "reaction_10061043", "reaction_10091611", "reaction_10058993", "reaction_10052043", "reaction_10083577", "reaction_10036038", "reaction_10076898", "reaction_10058913", "reaction_10066882", "reaction_10085808", "reaction_10043978", "reaction_10063430", "reaction_10063485", "reaction_10063442", "reaction_10091289", "reaction_10059984", "reaction_10059856", "reaction_10090175", "reaction_10034215", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10053266", "reaction_10078701", "reaction_10034924", "reaction_10036685", "reaction_10041319", "reaction_10041179", "reaction_10043980", "reaction_10060829", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10044232", "reaction_10083211", "reaction_10078402", "reaction_10071754", "reaction_10066619", "reaction_10090681", "reaction_10090679", "reaction_10044477", "reaction_10064491", "reaction_10071643", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10065225", "reaction_10041377", "reaction_10042961", "reaction_10041756", "reaction_10041172", "reaction_10035354", "reaction_10082948", "reaction_10044784", "reaction_10041486", "reaction_10038371", "reaction_10058834", "reaction_10043885", "reaction_10033681", "reaction_10058874", "reaction_10060827", "reaction_10090854", "reaction_10060295", "reaction_10041386", "reaction_10044182", "reaction_10059858", "reaction_10040881", "reaction_10066585", "reaction_10060109", "reaction_10040688", "reaction_10034206", "reaction_10035339", "reaction_10033912", "reaction_10042801", "reaction_10058896", "reaction_10090772", "reaction_10076261", "reaction_10044225", "reaction_10061014", "reaction_10076815", "reaction_10065371", "reaction_10039865", "reaction_10039604", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10077758", "reaction_10033797", "reaction_10035308", "reaction_10089850", "reaction_10041799", "reaction_10066574", "reaction_10041193", "reaction_10090498", "reaction_10067240", "reaction_10090510", "reaction_10040663", "reaction_10076974", "reaction_10090696", "reaction_10045050", "reaction_10058514", "reaction_10053350", "reaction_10048978", "reaction_10060498", "reaction_10063532", "reaction_10035342", "reaction_10068748", "reaction_10065386", "reaction_10034927", "reaction_10047022", "reaction_10041293", "reaction_10064595", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10061642", "reaction_10091598", "reaction_10034971", "reaction_10060917", "reaction_10074353", "reaction_10090384", "reaction_10075404", "reaction_10085788", "reaction_10058975", "reaction_10061031", "reaction_10041412", "reaction_10059847", "reaction_10044794", "reaction_10053298", "reaction_10034231", "reaction_10080517", "reaction_10083389", "reaction_10040129", "reaction_10063564", "reaction_10067634", "reaction_10085780", "reaction_10035444", "reaction_10057792", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10058511", "reaction_10078366", "reaction_10090489", "reaction_10059000", "reaction_10044167", "reaction_10034175", "reaction_10064578", "reaction_10040112", "reaction_10035020", "reaction_10059951", "reaction_10076799", "reaction_10034989", "reaction_10085853", "reaction_10038238", "reaction_10058910", "reaction_10035038", "reaction_10065455", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10040098", "reaction_10062508", "reaction_10060556", "reaction_10052027", "reaction_10063413", "reaction_10034043", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10042655", "reaction_10086064", "reaction_10063437", "reaction_10081346", "reaction_10062674", "reaction_10090867", "reaction_10036012", "reaction_10036907", "reaction_10038647", "reaction_10090464", "reaction_10058751", "reaction_10041955", "reaction_10090671", "reaction_10088926", "reaction_10066569", "reaction_10040147", "reaction_10060550", "reaction_10040682", "reaction_10041197", "reaction_10073477", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10088571", "reaction_10035958", "reaction_10066247", "reaction_10038918", "reaction_10044204", "reaction_10064581", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10063477", "reaction_10065441", "reaction_10033806", "reaction_10044216", "reaction_10040122", "reaction_10088898", "reaction_10084129", "reaction_10081984", "reaction_10057079", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10064591", "reaction_10060285", "reaction_10041831", "reaction_10061119", "reaction_10090474", "reaction_10043984", "reaction_10068755", "reaction_10051570", "reaction_10035332", "reaction_10051198", "reaction_10063448", "reaction_10034138", "reaction_10090797", "reaction_10066587", "reaction_10035007", "reaction_10046968", "reaction_10064439", "reaction_10033671", "reaction_10036238", "reaction_10046648", "reaction_10060021", "reaction_10085855", "reaction_10039887", "reaction_10077777", "reaction_10083926", "reaction_10065763", "reaction_10041297", "reaction_10036903", "reaction_10073438", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10089782", "reaction_10035029", "reaction_10034166", "reaction_10058880", "reaction_10063216", "reaction_10036209", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10035977", "reaction_10041781", "reaction_10083547", "reaction_10041284", "reaction_10051589", "reaction_10060634", "reaction_10040030", "reaction_10035481", "reaction_10036247", "reaction_10060597", "reaction_10034004", "reaction_10090508", "reaction_10062701", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10066401", "reaction_10041321", "reaction_10038380", "reaction_10090504", "reaction_10063508", "reaction_10081928", "reaction_10066444", "reaction_10033953", "reaction_10090392", "reaction_10038340", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10086469", "reaction_10041808", "reaction_10038942", "reaction_10066458", "reaction_10064597", "reaction_10061084", "reaction_10033561", "reaction_10053361", "reaction_10054601", "reaction_10084526", "reaction_10063428", "reaction_10061125", "reaction_10034157", "reaction_10063022", "reaction_10040021", "reaction_10060207", "reaction_10060252", "reaction_10051075", "reaction_10085381", "reaction_10039242", "reaction_10035479", "reaction_10035698", "reaction_10076903", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10042648", "reaction_10071729", "reaction_10044739", "reaction_10041721", "reaction_10040645", "reaction_10063249", "reaction_10060518", "reaction_10063510", "reaction_10061651", "reaction_10061017", "reaction_10071717", "reaction_10085340", "reaction_10060741", "reaction_10043971", "reaction_10065369", "reaction_10044776", "reaction_10058809", "reaction_10065381", "reaction_10044835", "reaction_10085185", "reaction_10078529", "reaction_10033755", "reaction_10086543", "reaction_10038231", "reaction_10041347", "reaction_10064355", "reaction_10040654", "reaction_10043924", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10034071", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10067254", "reaction_10046623", "reaction_10043917", "reaction_10089230", "reaction_10044851", "reaction_10065760", "reaction_10080756", "reaction_10050637", "reaction_10061024", "reaction_10063633", "reaction_10040152", "reaction_10061006", "reaction_10044270", "reaction_10039240", "reaction_10083864", "reaction_10045029", "reaction_10067425", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10090856", "reaction_10041373", "reaction_10033868", "reaction_10060535", "reaction_10086748", "reaction_10054395", "reaction_10063440", "reaction_10035838", "reaction_10067247", "reaction_10059014", "reaction_10082136", "reaction_10077496", "reaction_10043910", "reaction_10049346", "reaction_10088744", "reaction_10060685", "reaction_10041894", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10063801", "reaction_10077835", "reaction_10083889", "reaction_10047044", "reaction_10090799", "reaction_10065223", "reaction_10044828", "reaction_10058923", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10049161", "reaction_10066473", "reaction_10041737", "reaction_10085024", "reaction_10041379", "reaction_10072894", "reaction_10066602", "reaction_10044837", "reaction_10070971", "reaction_10060012", "reaction_10061046", "reaction_10090386", "reaction_10058877", "reaction_10047809", "reaction_10090611", "reaction_10083092", "reaction_10081977", "reaction_10076450", "reaction_10071924", "reaction_10057787", "reaction_10086248", "reaction_10061402", "reaction_10036229", "reaction_10035453", "reaction_10040107", "reaction_10060956", "reaction_10059121", "reaction_10061049", "reaction_10034921", "reaction_10040924", "reaction_10060951", "reaction_10076360", "reaction_10040117", "reaction_10083873", "reaction_10057684", "reaction_10041502", "reaction_10038316", "reaction_10058980", "reaction_10047033", "reaction_10057032", "reaction_10062984", "reaction_10044533", "reaction_10061128", "reaction_10058990", "reaction_10085806", "reaction_10057023", "reaction_10033716", "reaction_10059021", "reaction_10060514", "reaction_10044634", "reaction_10086550", "reaction_10060293", "reaction_10060611", "reaction_10033979", "reaction_10085374", "reaction_10052040", "reaction_10091613", "reaction_10064584", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10044275", "reaction_10059860", "reaction_10059961", "reaction_10048995", "reaction_10064593", "reaction_10049116", "reaction_10090822", "reaction_10086750", "reaction_10053363", "reaction_10060316", "reaction_10036928", "reaction_10090819", "reaction_10058722", "reaction_10077001", "reaction_10065362", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10076406", "reaction_10081349", "reaction_10076468", "reaction_10088019", "reaction_10041335", "reaction_10077751", "reaction_10038320", "reaction_10060218", "reaction_10064511", "reaction_10043964", "reaction_10042936", "reaction_10076144", "reaction_10033988", "reaction_10082889", "reaction_10090774", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10063586", "reaction_10041217", "reaction_10041765", "reaction_10044260", "reaction_10059150", "reaction_10077793", "reaction_10091936", "reaction_10064391" ] }, "R-BTA-975957": { "id": "pathway_10093896", "reactome": "R-BTA-975957", "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "reactions": [ "reaction_10053044" ] }, "R-BTA-912631": { "id": "pathway_10093882", "reactome": "R-BTA-912631", "name": "Regulation of signaling by CBL", "reactions": [ "reaction_10052323", "reaction_10052302", "reaction_10052294" ] }, "R-BTA-392170": { "id": "pathway_10093640", "reactome": "R-BTA-392170", "name": "ADP signalling through P2Y purinoceptor 12", "reactions": [ "reaction_10047857", "reaction_10047475" ] }, "R-BTA-210455": { "id": "pathway_10092494", "reactome": "R-BTA-210455", "name": "Astrocytic Glutamate-Glutamine Uptake And Metabolism", "reactions": [ "reaction_10033746", "reaction_10044086" ] }, "R-BTA-199220": { "id": "pathway_10093284", "reactome": "R-BTA-199220", "name": "Vitamin B5 (pantothenate) metabolism", "reactions": [ "reaction_10042648", "reaction_10041756", "reaction_10042655", "reaction_10041765", "reaction_10041744", "reaction_10041737" ] }, "R-BTA-202403": { "id": "pathway_10093350", "reactome": "R-BTA-202403", "name": "TCR signaling", "reactions": [ "reaction_10043262", "reaction_10043219", "reaction_10043212", "reaction_10043302", "reaction_10043300", "reaction_10043298", "reaction_10043193", "reaction_10043270", "reaction_10043304", "reaction_10043252", "reaction_10043244", "reaction_10043241", "reaction_10043225", "reaction_10043182", "reaction_10043274" ] }, "R-BTA-373755": { "id": "pathway_10093512", "reactome": "R-BTA-373755", "name": "Semaphorin interactions", "reactions": [ "reaction_10045244", "reaction_10047753", "reaction_10047735", "reaction_10047659", "reaction_10047618", "reaction_10047717", "reaction_10047763", "reaction_10045236" ] }, "R-BTA-8953854": { "id": "pathway_10092702", "reactome": "R-BTA-8953854", "name": "Metabolism of RNA", "reactions": [ "reaction_10049230", "reaction_10050342", "reaction_10049232", "reaction_10036003", "reaction_10050380", "reaction_10036917", "reaction_10050306", "reaction_10050366", "reaction_10050408", "reaction_10052963", "reaction_10050373", "reaction_10053044", "reaction_10050378", "reaction_10051221", "reaction_10050368", "reaction_10050318", "reaction_10036076", "reaction_10036915", "reaction_10041050", "reaction_10051066", "reaction_10041039", "reaction_10051219", "reaction_10036052", "reaction_10050400", "reaction_10036080" ] }, "R-BTA-210745": { "id": "pathway_10093426", "reactome": "R-BTA-210745", "name": "Regulation of gene expression in beta cells", "reactions": [ "reaction_10044090" ] }, "R-BTA-8939211": { "id": "pathway_10094820", "reactome": "R-BTA-8939211", "name": "ESR-mediated signaling", "reactions": [ "reaction_10091151", "reaction_10091275", "reaction_10091260", "reaction_10086662", "reaction_10091158", "reaction_10091118", "reaction_10092314", "reaction_10091271", "reaction_10091267", "reaction_10091115", "reaction_10089761", "reaction_10090712", "reaction_10091156" ] }, "R-BTA-167044": { "id": "pathway_10093106", "reactome": "R-BTA-167044", "name": "Signalling to RAS", "reactions": [ "reaction_10039736", "reaction_10040570", "reaction_10074879" ] }, "R-BTA-76061": { "id": "pathway_10092682", "reactome": "R-BTA-76061", "name": "RNA Polymerase III Transcription Initiation From Type 1 Promoter", "reactions": [ "reaction_10035854" ] }, "R-BTA-111933": { "id": "pathway_10092784", "reactome": "R-BTA-111933", "name": "Calmodulin induced events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-5683826": { "id": "pathway_10093684", "reactome": "R-BTA-5683826", "name": "Surfactant metabolism", "reactions": [ "reaction_10074833", "reaction_10091120", "reaction_10075095", "reaction_10075105", "reaction_10048761", "reaction_10074707", "reaction_10075125", "reaction_10091124", "reaction_10088922", "reaction_10048003", "reaction_10075086", "reaction_10077947", "reaction_10074857", "reaction_10074686", "reaction_10075084", "reaction_10075019", "reaction_10074869", "reaction_10074863", "reaction_10075023" ] }, "R-BTA-427652": { "id": "pathway_10093720", "reactome": "R-BTA-427652", "name": "Sodium-coupled phosphate cotransporters", "reactions": [ "reaction_10048761", "reaction_10048754", "reaction_10048747" ] }, "R-BTA-2161517": { "id": "pathway_10094234", "reactome": "R-BTA-2161517", "name": "Abacavir transmembrane transport", "reactions": [ "reaction_10064439" ] }, "R-BTA-8849175": { "id": "pathway_10094896", "reactome": "R-BTA-8849175", "name": "Threonine catabolism", "reactions": [ "reaction_10090162", "reaction_10090155" ] }, "R-BTA-2559583": { "id": "pathway_10093054", "reactome": "R-BTA-2559583", "name": "Cellular Senescence", "reactions": [ "reaction_10066630", "reaction_10066870", "reaction_10050192", "reaction_10076298", "reaction_10069684", "reaction_10074429", "reaction_10040355", "reaction_10088964", "reaction_10050208", "reaction_10068899", "reaction_10078369", "reaction_10039508", "reaction_10050231", "reaction_10066786", "reaction_10050256", "reaction_10066876", "reaction_10050218", "reaction_10076341", "reaction_10074446", "reaction_10076343", "reaction_10074453", "reaction_10066857", "reaction_10066779", "reaction_10068854", "reaction_10066832", "reaction_10066873", "reaction_10041950", "reaction_10068959", "reaction_10074431" ] }, "R-BTA-1234176": { "id": "pathway_10093988", "reactome": "R-BTA-1234176", "name": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha", "reactions": [ "reaction_10056688", "reaction_10056719", "reaction_10056754", "reaction_10056757", "reaction_10056759", "reaction_10056761", "reaction_10056737" ] }, "R-BTA-198765": { "id": "pathway_10093302", "reactome": "R-BTA-198765", "name": "Signalling to ERK5", "reactions": [ "reaction_10041917" ] }, "R-BTA-8979227": { "id": "pathway_10092674", "reactome": "R-BTA-8979227", "name": "Triglyceride metabolism", "reactions": [ "reaction_10083544", "reaction_10035795", "reaction_10035838", "reaction_10076847", "reaction_10080887", "reaction_10071388", "reaction_10035829", "reaction_10083547" ] }, "R-BTA-977444": { "id": "pathway_10093096", "reactome": "R-BTA-977444", "name": "GABA B receptor activation", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-193704": { "id": "pathway_10093260", "reactome": "R-BTA-193704", "name": "p75 NTR receptor-mediated signalling", "reactions": [ "reaction_10043744", "reaction_10043753", "reaction_10043778", "reaction_10043739", "reaction_10041333", "reaction_10041470", "reaction_10043877" ] }, "R-BTA-5607764": { "id": "pathway_10094470", "reactome": "R-BTA-5607764", "name": "CLEC7A (Dectin-1) signaling", "reactions": [ "reaction_10072053", "reaction_10072045", "reaction_10072032", "reaction_10072015", "reaction_10072002", "reaction_10072006", "reaction_10071948", "reaction_10072057", "reaction_10072061", "reaction_10072022", "reaction_10072030", "reaction_10071975", "reaction_10072011", "reaction_10071982" ] }, "R-BTA-629594": { "id": "pathway_10093846", "reactome": "R-BTA-629594", "name": "Highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051523", "reaction_10051521" ] }, "R-BTA-427359": { "id": "pathway_10093716", "reactome": "R-BTA-427359", "name": "SIRT1 negatively regulates rRNA expression", "reactions": [ "reaction_10048717", "reaction_10048720" ] }, "R-BTA-2028269": { "id": "pathway_10094198", "reactome": "R-BTA-2028269", "name": "Signaling by Hippo", "reactions": [ "reaction_10063317", "reaction_10063554", "reaction_10063380", "reaction_10063568", "reaction_10063342", "reaction_10063338", "reaction_10063305", "reaction_10063382", "reaction_10063550", "reaction_10063544", "reaction_10063556", "reaction_10063329", "reaction_10063534", "reaction_10063408", "reaction_10063346", "reaction_10063319" ] }, "R-BTA-190239": { "id": "pathway_10093190", "reactome": "R-BTA-190239", "name": "FGFR3 ligand binding and activation", "reactions": [ "reaction_10040753", "reaction_10040782", "reaction_10040761", "reaction_10083933", "reaction_10040779", "reaction_10083935" ] }, "R-BTA-69273": { "id": "pathway_10093086", "reactome": "R-BTA-69273", "name": "Cyclin A/B1/B2 associated events during G2/M transition", "reactions": [ "reaction_10039612", "reaction_10039614" ] }, "R-BTA-2559586": { "id": "pathway_10094380", "reactome": "R-BTA-2559586", "name": "DNA Damage/Telomere Stress Induced Senescence", "reactions": [ "reaction_10068854", "reaction_10078369", "reaction_10076298", "reaction_10069684", "reaction_10076341", "reaction_10074446", "reaction_10076343", "reaction_10068959", "reaction_10074453", "reaction_10074429", "reaction_10074431" ] }, "R-BTA-8951936": { "id": "pathway_10094844", "reactome": "R-BTA-8951936", "name": "RUNX3 regulates p14-ARF", "reactions": [ "reaction_10088006", "reaction_10087910", "reaction_10087900", "reaction_10087997", "reaction_10087889" ] }, "R-BTA-196807": { "id": "pathway_10093292", "reactome": "R-BTA-196807", "name": "Nicotinate metabolism", "reactions": [ "reaction_10071643", "reaction_10085365", "reaction_10088666", "reaction_10085374", "reaction_10085352", "reaction_10086623", "reaction_10065210", "reaction_10085362", "reaction_10041817", "reaction_10049170", "reaction_10086750", "reaction_10085359", "reaction_10081984", "reaction_10042915", "reaction_10081977", "reaction_10041824", "reaction_10041831", "reaction_10041808", "reaction_10082143", "reaction_10088867", "reaction_10042906", "reaction_10086748", "reaction_10086630" ] }, "R-BTA-168898": { "id": "pathway_10093002", "reactome": "R-BTA-168898", "name": "Toll-like Receptor Cascades", "reactions": [ "reaction_10050192", "reaction_10050196", "reaction_10040197", "reaction_10039481", "reaction_10085369", "reaction_10050208", "reaction_10060783", "reaction_10039560", "reaction_10060759", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10050218", "reaction_10060773", "reaction_10081905", "reaction_10081510", "reaction_10091739", "reaction_10039217", "reaction_10050254", "reaction_10053046", "reaction_10041950", "reaction_10081506", "reaction_10053048", "reaction_10043488", "reaction_10060785", "reaction_10065894" ] }, "R-BTA-165160": { "id": "pathway_10092952", "reactome": "R-BTA-165160", "name": "PDE3B signalling", "reactions": [ "reaction_10038450" ] }, "R-BTA-390247": { "id": "pathway_10093596", "reactome": "R-BTA-390247", "name": "Beta-oxidation of very long chain fatty acids", "reactions": [ "reaction_10082880", "reaction_10047058", "reaction_10075576", "reaction_10047053", "reaction_10077784", "reaction_10054592" ] }, "R-BTA-114452": { "id": "pathway_10092858", "reactome": "R-BTA-114452", "name": "Activation of BH3-only proteins", "reactions": [ "reaction_10037723", "reaction_10037739", "reaction_10037702", "reaction_10037727", "reaction_10037674", "reaction_10037678", "reaction_10037630", "reaction_10037706" ] }, "R-BTA-69615": { "id": "pathway_10092448", "reactome": "R-BTA-69615", "name": "G1/S DNA Damage Checkpoints", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-70370": { "id": "pathway_10092464", "reactome": "R-BTA-70370", "name": "Galactose catabolism", "reactions": [ "reaction_10033594", "reaction_10033579" ] }, "R-BTA-3270619": { "id": "pathway_10094210", "reactome": "R-BTA-3270619", "name": "IRF3-mediated induction of type I IFN", "reactions": [ "reaction_10065388", "reaction_10063376", "reaction_10065402", "reaction_10065407" ] }, "R-BTA-6803204": { "id": "pathway_10094668", "reactome": "R-BTA-6803204", "name": "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release", "reactions": [ "reaction_10081326", "reaction_10080457", "reaction_10081305", "reaction_10081323" ] }, "R-BTA-417957": { "id": "pathway_10093658", "reactome": "R-BTA-417957", "name": "P2Y receptors", "reactions": [ "reaction_10047866", "reaction_10047870", "reaction_10047868", "reaction_10047862", "reaction_10047864", "reaction_10047851", "reaction_10047853", "reaction_10047989", "reaction_10047857", "reaction_10090956", "reaction_10047860" ] }, "R-BTA-1474244": { "id": "pathway_10093318", "reactome": "R-BTA-1474244", "name": "Extracellular matrix organization", "reactions": [ "reaction_10087587", "reaction_10069313", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10065929", "reaction_10064649", "reaction_10076984", "reaction_10059787", "reaction_10062071", "reaction_10059651", "reaction_10059598", "reaction_10063839", "reaction_10058705", "reaction_10059869", "reaction_10059702", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10059533", "reaction_10064705", "reaction_10064953", "reaction_10087543", "reaction_10087626", "reaction_10059674", "reaction_10059913", "reaction_10044515", "reaction_10064435", "reaction_10059918", "reaction_10060191", "reaction_10058193", "reaction_10065292", "reaction_10060187", "reaction_10062377", "reaction_10064959", "reaction_10058561", "reaction_10065691", "reaction_10065336", "reaction_10065819", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10065300", "reaction_10087589", "reaction_10087324", "reaction_10059923", "reaction_10065751", "reaction_10068885", "reaction_10064337", "reaction_10065555", "reaction_10069412", "reaction_10061787", "reaction_10059902", "reaction_10059744", "reaction_10060003", "reaction_10059441", "reaction_10087567", "reaction_10059689", "reaction_10059731", "reaction_10042253", "reaction_10087569", "reaction_10065435", "reaction_10059804", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10064437", "reaction_10087579" ] }, "R-BTA-5654720": { "id": "pathway_10094542", "reactome": "R-BTA-5654720", "name": "PI-3K cascade:FGFR4", "reactions": [ "reaction_10073237", "reaction_10073192", "reaction_10073240" ] }, "R-BTA-166520": { "id": "pathway_10093018", "reactome": "R-BTA-166520", "name": "Signaling by NTRKs", "reactions": [ "reaction_10090994", "reaction_10039272", "reaction_10043315", "reaction_10040489", "reaction_10041917", "reaction_10041869", "reaction_10090666", "reaction_10039601", "reaction_10039736", "reaction_10041851", "reaction_10040570", "reaction_10039270", "reaction_10090727", "reaction_10042826", "reaction_10039581", "reaction_10040684", "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090954", "reaction_10074879", "reaction_10090675", "reaction_10039592", "reaction_10041950", "reaction_10090944", "reaction_10090722", "reaction_10043488", "reaction_10039711", "reaction_10040495" ] }, "R-BTA-211957": { "id": "pathway_10092688", "reactome": "R-BTA-211957", "name": "Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2", "reactions": [ "reaction_10035861", "reaction_10035865" ] }, "R-BTA-2029485": { "id": "pathway_10093298", "reactome": "R-BTA-2029485", "name": "Role of phospholipids in phagocytosis", "reactions": [ "reaction_10063368", "reaction_10041863" ] }, "R-BTA-212676": { "id": "pathway_10094444", "reactome": "R-BTA-212676", "name": "Dopamine Neurotransmitter Release Cycle", "reactions": [ "reaction_10071437" ] }, "R-BTA-174411": { "id": "pathway_10095016", "reactome": "R-BTA-174411", "name": "Polymerase switching on the C-strand of the telomere", "reactions": [ "reaction_10091663" ] }, "R-BTA-194306": { "id": "pathway_10093276", "reactome": "R-BTA-194306", "name": "Neurophilin interactions with VEGF and VEGFR", "reactions": [ "reaction_10041657" ] }, "R-BTA-173623": { "id": "pathway_10093110", "reactome": "R-BTA-173623", "name": "Classical antibody-mediated complement activation", "reactions": [ "reaction_10039782", "reaction_10039778" ] }, "R-BTA-73621": { "id": "pathway_10092590", "reactome": "R-BTA-73621", "name": "Pyrimidine catabolism", "reactions": [ "reaction_10034953", "reaction_10036267", "reaction_10036258", "reaction_10035009", "reaction_10036209", "reaction_10035011", "reaction_10034962", "reaction_10036229", "reaction_10036247", "reaction_10035481" ] }, "R-BTA-2243919": { "id": "pathway_10094310", "reactome": "R-BTA-2243919", "name": "Crosslinking of collagen fibrils", "reactions": [ "reaction_10065929" ] }, "R-BTA-8953750": { "id": "pathway_10094856", "reactome": "R-BTA-8953750", "name": "Transcriptional Regulation by E2F6", "reactions": [ "reaction_10089578", "reaction_10089574", "reaction_10088596", "reaction_10088584", "reaction_10088554", "reaction_10088564" ] }, "R-BTA-499943": { "id": "pathway_10092546", "reactome": "R-BTA-499943", "name": "Interconversion of nucleotide di- and triphosphates", "reactions": [ "reaction_10035047", "reaction_10035029", "reaction_10034166", "reaction_10082948", "reaction_10036683", "reaction_10034971", "reaction_10034998", "reaction_10051075", "reaction_10077890", "reaction_10036692", "reaction_10035038", "reaction_10035698", "reaction_10036938", "reaction_10036685" ] }, "R-BTA-9020265": { "id": "pathway_10094916", "reactome": "R-BTA-9020265", "name": "Biosynthesis of aspirin-triggered D-series resolvins", "reactions": [ "reaction_10090388" ] }, "R-BTA-5625970": { "id": "pathway_10094498", "reactome": "R-BTA-5625970", "name": "RHO GTPases activate KTN1", "reactions": [ "reaction_10073842", "reaction_10072515" ] }, "R-BTA-2187338": { "id": "pathway_10092628", "reactome": "R-BTA-2187338", "name": "Visual phototransduction", "reactions": [ "reaction_10065683", "reaction_10065597", "reaction_10035596", "reaction_10054382", "reaction_10054404", "reaction_10065644", "reaction_10035406", "reaction_10065604", "reaction_10065675", "reaction_10065664", "reaction_10088914", "reaction_10065944", "reaction_10035558", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065445", "reaction_10065673", "reaction_10066247", "reaction_10065437", "reaction_10054393", "reaction_10065441", "reaction_10066249", "reaction_10070971", "reaction_10069948", "reaction_10065679", "reaction_10065606", "reaction_10035619", "reaction_10077751", "reaction_10077744", "reaction_10065940", "reaction_10065677", "reaction_10035579", "reaction_10065808", "reaction_10065646", "reaction_10054375", "reaction_10054395" ] }, "R-BTA-110312": { "id": "pathway_10092760", "reactome": "R-BTA-110312", "name": "Translesion synthesis by REV1", "reactions": [ "reaction_10036853", "reaction_10036844" ] }, "R-BTA-5250913": { "id": "pathway_10094438", "reactome": "R-BTA-5250913", "name": "Positive epigenetic regulation of rRNA expression", "reactions": [ "reaction_10071065" ] }, "R-BTA-9034013": { "id": "pathway_10094962", "reactome": "R-BTA-9034013", "name": "NTF3 activates NTRK3 signaling", "reactions": [ "reaction_10090666" ] }, "R-BTA-3134975": { "id": "pathway_10094188", "reactome": "R-BTA-3134975", "name": "Regulation of innate immune responses to cytosolic DNA", "reactions": [ "reaction_10066536", "reaction_10066551", "reaction_10061502" ] }, "R-BTA-264870": { "id": "pathway_10093338", "reactome": "R-BTA-264870", "name": "Caspase-mediated cleavage of cytoskeletal proteins", "reactions": [ "reaction_10044756", "reaction_10044762", "reaction_10043049", "reaction_10043059", "reaction_10043021" ] }, "R-BTA-5218900": { "id": "pathway_10094364", "reactome": "R-BTA-5218900", "name": "CASP8 activity is inhibited", "reactions": [ "reaction_10068030", "reaction_10074240" ] }, "R-BTA-975574": { "id": "pathway_10093932", "reactome": "R-BTA-975574", "name": "Reactions specific to the hybrid N-glycan synthesis pathway", "reactions": [ "reaction_10054474" ] }, "R-BTA-6798163": { "id": "pathway_10094136", "reactome": "R-BTA-6798163", "name": "Choline catabolism", "reactions": [ "reaction_10060275", "reaction_10078582", "reaction_10078575" ] }, "R-BTA-6811438": { "id": "pathway_10094706", "reactome": "R-BTA-6811438", "name": "Intra-Golgi traffic", "reactions": [ "reaction_10083458", "reaction_10083767", "reaction_10083451", "reaction_10083425", "reaction_10083056" ] }, "R-BTA-69231": { "id": "pathway_10093136", "reactome": "R-BTA-69231", "name": "Cyclin D associated events in G1", "reactions": [ "reaction_10056602", "reaction_10056616", "reaction_10087394", "reaction_10087487", "reaction_10057821", "reaction_10057816", "reaction_10087385", "reaction_10040355", "reaction_10087503" ] }, "R-BTA-453279": { "id": "pathway_10092410", "reactome": "R-BTA-453279", "name": "Mitotic G1 phase and G1/S transition", "reactions": [ "reaction_10057804", "reaction_10040542", "reaction_10040355", "reaction_10087503", "reaction_10033512", "reaction_10057812", "reaction_10087487", "reaction_10033466", "reaction_10057816", "reaction_10040576", "reaction_10040503", "reaction_10057808", "reaction_10056602", "reaction_10040521", "reaction_10087394", "reaction_10057821", "reaction_10083558", "reaction_10087385", "reaction_10056616", "reaction_10083565", "reaction_10057800" ] }, "R-BTA-8856828": { "id": "pathway_10094780", "reactome": "R-BTA-8856828", "name": "Clathrin-mediated endocytosis", "reactions": [ "reaction_10085313", "reaction_10084824", "reaction_10084757", "reaction_10091753", "reaction_10085134", "reaction_10084822", "reaction_10085264", "reaction_10084819", "reaction_10085166", "reaction_10085116" ] }, "R-BTA-72613": { "id": "pathway_10092578", "reactome": "R-BTA-72613", "name": "Eukaryotic Translation Initiation", "reactions": [ "reaction_10034855", "reaction_10038082", "reaction_10034365", "reaction_10034383", "reaction_10034387", "reaction_10034905" ] }, "R-BTA-8956319": { "id": "pathway_10092592", "reactome": "R-BTA-8956319", "name": "Nucleobase catabolism", "reactions": [ "reaction_10034953", "reaction_10035464", "reaction_10065359", "reaction_10083926", "reaction_10065763", "reaction_10035455", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10088571", "reaction_10065381", "reaction_10036231", "reaction_10036267", "reaction_10083889", "reaction_10035009", "reaction_10036209", "reaction_10036207", "reaction_10036247", "reaction_10035481", "reaction_10065378", "reaction_10036258", "reaction_10065362", "reaction_10065371", "reaction_10036256", "reaction_10065760", "reaction_10036229", "reaction_10035453", "reaction_10083864", "reaction_10083876", "reaction_10083852", "reaction_10035011", "reaction_10083873", "reaction_10083861", "reaction_10034962", "reaction_10065383", "reaction_10036238", "reaction_10065386" ] }, "R-BTA-166166": { "id": "pathway_10093072", "reactome": "R-BTA-166166", "name": "MyD88-independent TLR4 cascade ", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-2559580": { "id": "pathway_10093052", "reactome": "R-BTA-2559580", "name": "Oxidative Stress Induced Senescence", "reactions": [ "reaction_10066876", "reaction_10050208", "reaction_10066870", "reaction_10050192", "reaction_10066832", "reaction_10050218", "reaction_10066873", "reaction_10039508", "reaction_10050231", "reaction_10066857", "reaction_10050256", "reaction_10040355", "reaction_10066786", "reaction_10066779", "reaction_10088964" ] }, "R-BTA-163560": { "id": "pathway_10094442", "reactome": "R-BTA-163560", "name": "Triglyceride catabolism", "reactions": [ "reaction_10083547", "reaction_10083544", "reaction_10071388" ] }, "R-BTA-5654741": { "id": "pathway_10093192", "reactome": "R-BTA-5654741", "name": "Signaling by FGFR3", "reactions": [ "reaction_10073014", "reaction_10072946", "reaction_10073147", "reaction_10057327", "reaction_10073019", "reaction_10073145", "reaction_10040779", "reaction_10073234", "reaction_10057314", "reaction_10057329", "reaction_10059156", "reaction_10053082", "reaction_10083935", "reaction_10073021", "reaction_10073011", "reaction_10057318", "reaction_10072944", "reaction_10040753", "reaction_10073152", "reaction_10083933", "reaction_10073140", "reaction_10087376", "reaction_10073244", "reaction_10072913", "reaction_10073159", "reaction_10057323", "reaction_10073156", "reaction_10040761", "reaction_10057337", "reaction_10073215", "reaction_10040782", "reaction_10057302" ] }, "R-BTA-5654727": { "id": "pathway_10093908", "reactome": "R-BTA-5654727", "name": "Negative regulation of FGFR2 signaling", "reactions": [ "reaction_10059156", "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10073242", "reaction_10057337", "reaction_10053082", "reaction_10073208", "reaction_10057302" ] }, "R-BTA-68962": { "id": "pathway_10092406", "reactome": "R-BTA-68962", "name": "Activation of the pre-replicative complex", "reactions": [ "reaction_10033512", "reaction_10033466" ] }, "R-BTA-177162": { "id": "pathway_10093130", "reactome": "R-BTA-177162", "name": "Conjugation of phenylacetate with glutamine", "reactions": [ "reaction_10040185" ] }, "R-BTA-1483248": { "id": "pathway_10094154", "reactome": "R-BTA-1483248", "name": "Synthesis of PIPs at the ER membrane", "reactions": [ "reaction_10060476" ] }, "R-BTA-450604": { "id": "pathway_10093810", "reactome": "R-BTA-450604", "name": "KSRP (KHSRP) binds and destabilizes mRNA", "reactions": [ "reaction_10050380", "reaction_10050408" ] }, "R-BTA-141405": { "id": "pathway_10092892", "reactome": "R-BTA-141405", "name": "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components", "reactions": [ "reaction_10038033", "reaction_10038035" ] }, "R-BTA-168179": { "id": "pathway_10093044", "reactome": "R-BTA-168179", "name": "Toll Like Receptor TLR1:TLR2 Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-174824": { "id": "pathway_10093460", "reactome": "R-BTA-174824", "name": "Plasma lipoprotein assembly, remodeling, and clearance", "reactions": [ "reaction_10074474", "reaction_10044547", "reaction_10074486", "reaction_10084509", "reaction_10086004", "reaction_10086002", "reaction_10084300", "reaction_10086026", "reaction_10083113", "reaction_10086557", "reaction_10085994", "reaction_10077487", "reaction_10077489", "reaction_10088982", "reaction_10044666" ] }, "R-BTA-5693532": { "id": "pathway_10092660", "reactome": "R-BTA-5693532", "name": "DNA Double-Strand Break Repair", "reactions": [ "reaction_10076347", "reaction_10075306", "reaction_10076327", "reaction_10076334", "reaction_10076298", "reaction_10074550", "reaction_10074670", "reaction_10075304", "reaction_10076339", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10074798", "reaction_10074720", "reaction_10035720", "reaction_10075151", "reaction_10075295", "reaction_10074747", "reaction_10075037", "reaction_10035846", "reaction_10076312", "reaction_10076286", "reaction_10074677", "reaction_10076303", "reaction_10075319", "reaction_10074695", "reaction_10075165", "reaction_10035712", "reaction_10076329", "reaction_10075326", "reaction_10076341", "reaction_10076343", "reaction_10074453", "reaction_10074692", "reaction_10076332", "reaction_10075181", "reaction_10074877", "reaction_10074759", "reaction_10074736", "reaction_10068854", "reaction_10074761", "reaction_10074679", "reaction_10075323", "reaction_10075173" ] }, "R-BTA-186712": { "id": "pathway_10093428", "reactome": "R-BTA-186712", "name": "Regulation of beta-cell development", "reactions": [ "reaction_10044090" ] }, "R-BTA-1296072": { "id": "pathway_10094040", "reactome": "R-BTA-1296072", "name": "Voltage gated Potassium channels", "reactions": [ "reaction_10057569" ] }, "R-BTA-68877": { "id": "pathway_10094304", "reactome": "R-BTA-68877", "name": "Mitotic Prometaphase", "reactions": [ "reaction_10065794" ] }, "R-BTA-212436": { "id": "pathway_10092436", "reactome": "R-BTA-212436", "name": "Generic Transcription Pathway", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10072557", "reaction_10086241", "reaction_10088546", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-451326": { "id": "pathway_10093816", "reactome": "R-BTA-451326", "name": "Activation of kainate receptors upon glutamate binding", "reactions": [ "reaction_10050514", "reaction_10051085", "reaction_10050517" ] }, "R-BTA-73942": { "id": "pathway_10094776", "reactome": "R-BTA-73942", "name": "DNA Damage Reversal", "reactions": [ "reaction_10084497" ] }, "R-BTA-9023661": { "id": "pathway_10094910", "reactome": "R-BTA-9023661", "name": "Biosynthesis of E-series 18(R)-resolvins", "reactions": [ "reaction_10090382", "reaction_10090379" ] }, "R-BTA-5693537": { "id": "pathway_10094600", "reactome": "R-BTA-5693537", "name": "Resolution of D-Loop Structures", "reactions": [ "reaction_10075165", "reaction_10075151" ] }, "R-BTA-8937144": { "id": "pathway_10094816", "reactome": "R-BTA-8937144", "name": "Aryl hydrocarbon receptor signalling", "reactions": [ "reaction_10086543" ] }, "R-BTA-6811440": { "id": "pathway_10094712", "reactome": "R-BTA-6811440", "name": "Retrograde transport at the Trans-Golgi-Network", "reactions": [ "reaction_10083340", "reaction_10083342", "reaction_10083143", "reaction_10083179", "reaction_10083187", "reaction_10083149" ] }, "R-BTA-168164": { "id": "pathway_10093062", "reactome": "R-BTA-168164", "name": "Toll Like Receptor 3 (TLR3) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-77348": { "id": "pathway_10092714", "reactome": "R-BTA-77348", "name": "Beta oxidation of octanoyl-CoA to hexanoyl-CoA", "reactions": [ "reaction_10036038", "reaction_10036029" ] }, "R-BTA-110320": { "id": "pathway_10092766", "reactome": "R-BTA-110320", "name": "Translesion Synthesis by POLH", "reactions": [ "reaction_10036886", "reaction_10073279", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036879", "reaction_10036869" ] }, "R-BTA-190373": { "id": "pathway_10093178", "reactome": "R-BTA-190373", "name": "FGFR1c ligand binding and activation", "reactions": [ "reaction_10040794", "reaction_10040704" ] }, "R-BTA-8854050": { "id": "pathway_10094760", "reactome": "R-BTA-8854050", "name": "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis", "reactions": [ "reaction_10084214", "reaction_10084102", "reaction_10084206", "reaction_10084216" ] }, "R-BTA-6811558": { "id": "pathway_10094146", "reactome": "R-BTA-6811558", "name": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling", "reactions": [ "reaction_10060556", "reaction_10060448" ] }, "R-BTA-73894": { "id": "pathway_10092662", "reactome": "R-BTA-73894", "name": "DNA Repair", "reactions": [ "reaction_10076071", "reaction_10076009", "reaction_10074670", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10073279", "reaction_10091222", "reaction_10036709", "reaction_10074747", "reaction_10036736", "reaction_10076312", "reaction_10076303", "reaction_10075165", "reaction_10071769", "reaction_10076341", "reaction_10075181", "reaction_10074736", "reaction_10036869", "reaction_10036782", "reaction_10036767", "reaction_10071638", "reaction_10077591", "reaction_10075323", "reaction_10076327", "reaction_10091566", "reaction_10036760", "reaction_10075304", "reaction_10073290", "reaction_10074798", "reaction_10071617", "reaction_10074720", "reaction_10071630", "reaction_10036844", "reaction_10088526", "reaction_10091211", "reaction_10073275", "reaction_10075037", "reaction_10091233", "reaction_10071607", "reaction_10084497", "reaction_10036886", "reaction_10075326", "reaction_10071622", "reaction_10076343", "reaction_10076332", "reaction_10074759", "reaction_10036805", "reaction_10036716", "reaction_10074761", "reaction_10075173", "reaction_10076347", "reaction_10071628", "reaction_10071765", "reaction_10076298", "reaction_10074550", "reaction_10036661", "reaction_10076339", "reaction_10036743", "reaction_10035720", "reaction_10075151", "reaction_10036729", "reaction_10071640", "reaction_10072876", "reaction_10076286", "reaction_10075319", "reaction_10077108", "reaction_10036853", "reaction_10036798", "reaction_10074679", "reaction_10077593", "reaction_10075306", "reaction_10077016", "reaction_10071767", "reaction_10077396", "reaction_10073302", "reaction_10036791", "reaction_10075295", "reaction_10073254", "reaction_10035846", "reaction_10074695", "reaction_10074677", "reaction_10035712", "reaction_10076329", "reaction_10077625", "reaction_10074453", "reaction_10074692", "reaction_10074877", "reaction_10091240", "reaction_10072883", "reaction_10068854", "reaction_10076334", "reaction_10036879" ] }, "R-BTA-2162123": { "id": "pathway_10092868", "reactome": "R-BTA-2162123", "name": "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)", "reactions": [ "reaction_10037751", "reaction_10065210", "reaction_10065213", "reaction_10065223", "reaction_10065225", "reaction_10065216", "reaction_10064465", "reaction_10044599", "reaction_10064442", "reaction_10064479", "reaction_10064452", "reaction_10064445", "reaction_10064474", "reaction_10037748" ] }, "R-BTA-2022923": { "id": "pathway_10094196", "reactome": "R-BTA-2022923", "name": "Dermatan sulfate biosynthesis", "reactions": [ "reaction_10062508", "reaction_10062674", "reaction_10062701", "reaction_10062697" ] }, "R-BTA-3928662": { "id": "pathway_10094390", "reactome": "R-BTA-3928662", "name": "EPHB-mediated forward signaling", "reactions": [ "reaction_10069435", "reaction_10069144", "reaction_10069148" ] }, "R-BTA-2168880": { "id": "pathway_10094262", "reactome": "R-BTA-2168880", "name": "Scavenging of heme from plasma", "reactions": [ "reaction_10065163", "reaction_10065173", "reaction_10064753", "reaction_10064757", "reaction_10064765" ] }, "R-BTA-112310": { "id": "pathway_10092504", "reactome": "R-BTA-112310", "name": "Neurotransmitter release cycle", "reactions": [ "reaction_10044076", "reaction_10033755", "reaction_10044540", "reaction_10052018", "reaction_10052013", "reaction_10051999", "reaction_10045419", "reaction_10081481", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10071437", "reaction_10049090", "reaction_10051989", "reaction_10049583" ] }, "R-BTA-196791": { "id": "pathway_10093406", "reactome": "R-BTA-196791", "name": "Vitamin D (calciferol) metabolism", "reactions": [ "reaction_10043984", "reaction_10044741", "reaction_10043903", "reaction_10044739", "reaction_10043910", "reaction_10043885", "reaction_10043964", "reaction_10088928", "reaction_10043971", "reaction_10088926" ] }, "R-BTA-69416": { "id": "pathway_10092614", "reactome": "R-BTA-69416", "name": "Dimerization of procaspase-8", "reactions": [ "reaction_10037991", "reaction_10037985", "reaction_10035396" ] }, "R-BTA-975871": { "id": "pathway_10093032", "reactome": "R-BTA-975871", "name": "MyD88 cascade initiated on plasma membrane", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1855204": { "id": "pathway_10094166", "reactome": "R-BTA-1855204", "name": "Synthesis of IP3 and IP4 in the cytosol", "reactions": [ "reaction_10061084", "reaction_10061076", "reaction_10060917", "reaction_10061113", "reaction_10061006" ] }, "R-BTA-111469": { "id": "pathway_10092832", "reactome": "R-BTA-111469", "name": "SMAC, XIAP-regulated apoptotic response", "reactions": [ "reaction_10091188", "reaction_10037289", "reaction_10091191", "reaction_10037293", "reaction_10091197" ] }, "R-BTA-163685": { "id": "pathway_10092980", "reactome": "R-BTA-163685", "name": "Integration of energy metabolism", "reactions": [ "reaction_10038942", "reaction_10047765", "reaction_10047809", "reaction_10046642", "reaction_10083614", "reaction_10038918", "reaction_10049346", "reaction_10046623", "reaction_10049351", "reaction_10044634", "reaction_10046630", "reaction_10038938", "reaction_10046648" ] }, "R-BTA-69242": { "id": "pathway_10092422", "reactome": "R-BTA-69242", "name": "S Phase", "reactions": [ "reaction_10035745", "reaction_10033504", "reaction_10040521", "reaction_10083565", "reaction_10040183", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10035747", "reaction_10083558", "reaction_10033473" ] }, "R-BTA-5654704": { "id": "pathway_10094540", "reactome": "R-BTA-5654704", "name": "SHC-mediated cascade:FGFR3", "reactions": [ "reaction_10073140", "reaction_10073152", "reaction_10073159", "reaction_10073156" ] }, "R-BTA-880009": { "id": "pathway_10093874", "reactome": "R-BTA-880009", "name": "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate", "reactions": [ "reaction_10051980", "reaction_10051973" ] }, "R-BTA-418594": { "id": "pathway_10092776", "reactome": "R-BTA-418594", "name": "G alpha (i) signalling events", "reactions": [ "reaction_10037037", "reaction_10089211", "reaction_10039653", "reaction_10037045", "reaction_10039676", "reaction_10088940", "reaction_10039667", "reaction_10039671", "reaction_10039674", "reaction_10036959", "reaction_10039664", "reaction_10039658", "reaction_10089214", "reaction_10089197", "reaction_10037024", "reaction_10036981", "reaction_10037022", "reaction_10037004", "reaction_10048370", "reaction_10049478", "reaction_10039485", "reaction_10046534", "reaction_10039651", "reaction_10088942" ] }, "R-BTA-8866911": { "id": "pathway_10094786", "reactome": "R-BTA-8866911", "name": "TFAP2 (AP-2) family regulates transcription of cell cycle factors", "reactions": [ "reaction_10084935" ] }, "R-BTA-622327": { "id": "pathway_10093848", "reactome": "R-BTA-622327", "name": "Postsynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051523", "reaction_10051521" ] }, "R-BTA-166208": { "id": "pathway_10092998", "reactome": "R-BTA-166208", "name": "mTORC1-mediated signalling", "reactions": [ "reaction_10091741", "reaction_10039160", "reaction_10039200", "reaction_10039209", "reaction_10039155", "reaction_10039180" ] }, "R-BTA-373076": { "id": "pathway_10093502", "reactome": "R-BTA-373076", "name": "Class A/1 (Rhodopsin-like receptors)", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048208", "reaction_10047396", "reaction_10045072", "reaction_10049617", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10053333", "reaction_10046733", "reaction_10047332", "reaction_10078536", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10067358", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-2262752": { "id": "pathway_10092554", "reactome": "R-BTA-2262752", "name": "Cellular responses to stress", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273" ] }, "R-BTA-5250924": { "id": "pathway_10094436", "reactome": "R-BTA-5250924", "name": "B-WICH complex positively regulates rRNA expression", "reactions": [ "reaction_10071065" ] }, "R-BTA-75153": { "id": "pathway_10093342", "reactome": "R-BTA-75153", "name": "Apoptotic execution phase", "reactions": [ "reaction_10044568", "reaction_10044116", "reaction_10043049", "reaction_10044146", "reaction_10043039", "reaction_10044756", "reaction_10044762", "reaction_10044995", "reaction_10044896", "reaction_10044927", "reaction_10044869", "reaction_10044578", "reaction_10044142", "reaction_10043059", "reaction_10044680", "reaction_10043021", "reaction_10090573", "reaction_10044923", "reaction_10090575", "reaction_10044144", "reaction_10044906" ] }, "R-BTA-5654712": { "id": "pathway_10094530", "reactome": "R-BTA-5654712", "name": "FRS-mediated FGFR4 signaling", "reactions": [ "reaction_10073184", "reaction_10073177", "reaction_10073175", "reaction_10073028", "reaction_10073182", "reaction_10087367", "reaction_10073166", "reaction_10073031" ] }, "R-BTA-9018682": { "id": "pathway_10094944", "reactome": "R-BTA-9018682", "name": "Biosynthesis of maresins", "reactions": [ "reaction_10090498" ] }, "R-BTA-190242": { "id": "pathway_10093172", "reactome": "R-BTA-190242", "name": "FGFR1 ligand binding and activation", "reactions": [ "reaction_10040773", "reaction_10040704", "reaction_10040791", "reaction_10040794", "reaction_10040696", "reaction_10040860" ] }, "R-BTA-434313": { "id": "pathway_10093756", "reactome": "R-BTA-434313", "name": "Intracellular metabolism of fatty acids regulates insulin secretion", "reactions": [ "reaction_10049351", "reaction_10049346" ] }, "R-BTA-1250342": { "id": "pathway_10094018", "reactome": "R-BTA-1250342", "name": "PI3K events in ERBB4 signaling", "reactions": [ "reaction_10057184" ] }, "R-BTA-425397": { "id": "pathway_10092728", "reactome": "R-BTA-425397", "name": "Transport of vitamins, nucleosides, and related molecules", "reactions": [ "reaction_10051892", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10036283", "reaction_10051587", "reaction_10051577", "reaction_10039874", "reaction_10036297", "reaction_10071001", "reaction_10051879", "reaction_10051554", "reaction_10038660", "reaction_10070928", "reaction_10051899", "reaction_10091250", "reaction_10051589", "reaction_10071003", "reaction_10051866", "reaction_10036290", "reaction_10073838", "reaction_10049080", "reaction_10051570", "reaction_10036276", "reaction_10051545", "reaction_10051843", "reaction_10051547" ] }, "R-BTA-6787639": { "id": "pathway_10094648", "reactome": "R-BTA-6787639", "name": "GDP-fucose biosynthesis", "reactions": [ "reaction_10077826", "reaction_10077800", "reaction_10077807", "reaction_10077823", "reaction_10077816" ] }, "R-BTA-6811434": { "id": "pathway_10094700", "reactome": "R-BTA-6811434", "name": "COPI-dependent Golgi-to-ER retrograde traffic", "reactions": [ "reaction_10083004", "reaction_10083006", "reaction_10082999" ] }, "R-BTA-9018676": { "id": "pathway_10094918", "reactome": "R-BTA-9018676", "name": "Biosynthesis of D-series resolvins", "reactions": [ "reaction_10090458", "reaction_10090390" ] }, "R-BTA-162710": { "id": "pathway_10092956", "reactome": "R-BTA-162710", "name": "Synthesis of glycosylphosphatidylinositol (GPI)", "reactions": [ "reaction_10038464", "reaction_10038457" ] }, "R-BTA-1793185": { "id": "pathway_10094124", "reactome": "R-BTA-1793185", "name": "Chondroitin sulfate/dermatan sulfate metabolism", "reactions": [ "reaction_10061395", "reaction_10061642", "reaction_10061350", "reaction_10061651", "reaction_10062697", "reaction_10061612", "reaction_10060827", "reaction_10062655", "reaction_10063807", "reaction_10060825", "reaction_10060842", "reaction_10060031", "reaction_10062701", "reaction_10091289", "reaction_10061402", "reaction_10061251", "reaction_10063014", "reaction_10062508", "reaction_10060829", "reaction_10062463", "reaction_10062674", "reaction_10091286" ] }, "R-BTA-69481": { "id": "pathway_10093126", "reactome": "R-BTA-69481", "name": "G2/M Checkpoints", "reactions": [ "reaction_10084051", "reaction_10084047", "reaction_10074692", "reaction_10074695", "reaction_10040059" ] }, "R-BTA-6783984": { "id": "pathway_10094630", "reactome": "R-BTA-6783984", "name": "Glycine degradation", "reactions": [ "reaction_10076441", "reaction_10076459", "reaction_10076450" ] }, "R-BTA-75205": { "id": "pathway_10092916", "reactome": "R-BTA-75205", "name": "Dissolution of Fibrin Clot", "reactions": [ "reaction_10038307", "reaction_10038292", "reaction_10038303", "reaction_10038288", "reaction_10038263", "reaction_10038270", "reaction_10038329", "reaction_10038290", "reaction_10038285" ] }, "R-BTA-5576890": { "id": "pathway_10094456", "reactome": "R-BTA-5576890", "name": "Phase 3 - rapid repolarisation", "reactions": [ "reaction_10071824", "reaction_10071800" ] }, "R-BTA-977068": { "id": "pathway_10093938", "reactome": "R-BTA-977068", "name": "Termination of O-glycan biosynthesis", "reactions": [ "reaction_10054550", "reaction_10054766", "reaction_10054722", "reaction_10054575", "reaction_10054773" ] }, "R-BTA-400042": { "id": "pathway_10093650", "reactome": "R-BTA-400042", "name": "Adrenaline,noradrenaline inhibits insulin secretion", "reactions": [ "reaction_10047765" ] }, "R-BTA-5683057": { "id": "pathway_10094572", "reactome": "R-BTA-5683057", "name": "MAPK family signaling cascades", "reactions": [ "reaction_10075253", "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10075239", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10075262", "reaction_10091490", "reaction_10076229", "reaction_10073904", "reaction_10091506", "reaction_10075205", "reaction_10073932", "reaction_10074238", "reaction_10076193", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10075251", "reaction_10075256", "reaction_10074088", "reaction_10075916", "reaction_10075906", "reaction_10075260", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10076198", "reaction_10073940", "reaction_10075223", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10075218", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-400451": { "id": "pathway_10093656", "reactome": "R-BTA-400451", "name": "Free fatty acids regulate insulin secretion", "reactions": [ "reaction_10049351", "reaction_10049346", "reaction_10047809" ] }, "R-BTA-9026762": { "id": "pathway_10094936", "reactome": "R-BTA-9026762", "name": "Biosynthesis of maresin conjugates in tissue regeneration (MCTR)", "reactions": [ "reaction_10090480", "reaction_10090489" ] }, "R-BTA-5654228": { "id": "pathway_10094518", "reactome": "R-BTA-5654228", "name": "Phospholipase C-mediated cascade; FGFR4", "reactions": [ "reaction_10072927", "reaction_10072933", "reaction_10072939" ] }, "R-BTA-170834": { "id": "pathway_10094274", "reactome": "R-BTA-170834", "name": "Signaling by TGF-beta Receptor Complex", "reactions": [ "reaction_10064933", "reaction_10071262" ] }, "R-BTA-156582": { "id": "pathway_10092918", "reactome": "R-BTA-156582", "name": "Acetylation", "reactions": [ "reaction_10039918", "reaction_10039921", "reaction_10038316", "reaction_10039923" ] }, "R-BTA-5660526": { "id": "pathway_10094552", "reactome": "R-BTA-5660526", "name": "Response to metal ions", "reactions": [ "reaction_10073446", "reaction_10073481", "reaction_10073460", "reaction_10073468", "reaction_10073464" ] }, "R-BTA-5653656": { "id": "pathway_10093214", "reactome": "R-BTA-5653656", "name": "Vesicle-mediated transport", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10065163", "reaction_10076775", "reaction_10076590", "reaction_10043649", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10064765", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10064753", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10064757", "reaction_10084261", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10086209", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10065173", "reaction_10083342", "reaction_10040961", "reaction_10076778", "reaction_10083767", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-196849": { "id": "pathway_10092518", "reactome": "R-BTA-196849", "name": "Metabolism of water-soluble vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10092306", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10066401", "reaction_10041772", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10041840", "reaction_10041790", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10053350", "reaction_10086748", "reaction_10041753", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10081977", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10086750", "reaction_10086763", "reaction_10053363", "reaction_10081984", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-8852276": { "id": "pathway_10094756", "reactome": "R-BTA-8852276", "name": "The role of GTSE1 in G2/M progression after G2 checkpoint", "reactions": [ "reaction_10084043", "reaction_10084051", "reaction_10084028", "reaction_10084047" ] }, "R-BTA-8876725": { "id": "pathway_10094644", "reactome": "R-BTA-8876725", "name": "Protein methylation", "reactions": [ "reaction_10086286", "reaction_10086303", "reaction_10077744", "reaction_10086319" ] }, "R-BTA-165158": { "id": "pathway_10092736", "reactome": "R-BTA-165158", "name": "Activation of AKT2", "reactions": [ "reaction_10036590", "reaction_10036607", "reaction_10036598" ] }, "R-BTA-9013404": { "id": "pathway_10094892", "reactome": "R-BTA-9013404", "name": "RAC2 GTPase cycle", "reactions": [ "reaction_10090089", "reaction_10092370", "reaction_10092380", "reaction_10090091", "reaction_10090087", "reaction_10090077", "reaction_10092382", "reaction_10090082" ] }, "R-BTA-8964038": { "id": "pathway_10094708", "reactome": "R-BTA-8964038", "name": "LDL clearance", "reactions": [ "reaction_10086004", "reaction_10086002", "reaction_10086026", "reaction_10086557", "reaction_10083113", "reaction_10085994" ] }, "R-BTA-70171": { "id": "pathway_10092472", "reactome": "R-BTA-70171", "name": "Glycolysis", "reactions": [ "reaction_10033611", "reaction_10034071", "reaction_10033629", "reaction_10078710", "reaction_10076815", "reaction_10033620", "reaction_10034157", "reaction_10088737", "reaction_10080765", "reaction_10034140" ] }, "R-BTA-622312": { "id": "pathway_10093866", "reactome": "R-BTA-622312", "name": "Inflammasomes", "reactions": [ "reaction_10051836" ] }, "R-BTA-354192": { "id": "pathway_10093492", "reactome": "R-BTA-354192", "name": "Integrin signaling", "reactions": [ "reaction_10049279", "reaction_10049506", "reaction_10045016", "reaction_10053213" ] }, "R-BTA-162658": { "id": "pathway_10094276", "reactome": "R-BTA-162658", "name": "Golgi Cisternae Pericentriolar Stack Reorganization", "reactions": [ "reaction_10065095" ] }, "R-BTA-194068": { "id": "pathway_10092928", "reactome": "R-BTA-194068", "name": "Bile acid and bile salt metabolism", "reactions": [ "reaction_10041337", "reaction_10085806", "reaction_10041197", "reaction_10041377", "reaction_10041172", "reaction_10041308", "reaction_10041343", "reaction_10041363", "reaction_10041177", "reaction_10041208", "reaction_10085316", "reaction_10041104", "reaction_10041357", "reaction_10085291", "reaction_10041226", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041323", "reaction_10041349", "reaction_10038347", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041351", "reaction_10041371", "reaction_10041375", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041437", "reaction_10041335", "reaction_10041210", "reaction_10041327", "reaction_10041193", "reaction_10041353", "reaction_10041317", "reaction_10041361", "reaction_10041345", "reaction_10041204", "reaction_10041319", "reaction_10041367", "reaction_10041339", "reaction_10041097", "reaction_10041179", "reaction_10041217", "reaction_10041206", "reaction_10041301", "reaction_10041373", "reaction_10041195", "reaction_10041369" ] }, "R-BTA-1474151": { "id": "pathway_10094084", "reactome": "R-BTA-1474151", "name": "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation", "reactions": [ "reaction_10058511", "reaction_10058524", "reaction_10058785", "reaction_10058514" ] }, "R-BTA-1834949": { "id": "pathway_10094190", "reactome": "R-BTA-1834949", "name": "Cytosolic sensors of pathogen-associated DNA ", "reactions": [ "reaction_10063376", "reaction_10066551", "reaction_10066559", "reaction_10066880", "reaction_10067229", "reaction_10066536", "reaction_10067223", "reaction_10067231", "reaction_10067225", "reaction_10065402", "reaction_10065388", "reaction_10065413", "reaction_10067216", "reaction_10090837", "reaction_10061502", "reaction_10066608", "reaction_10065407", "reaction_10090019", "reaction_10067233", "reaction_10066532" ] }, "R-BTA-5358565": { "id": "pathway_10094450", "reactome": "R-BTA-5358565", "name": "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)", "reactions": [ "reaction_10071628", "reaction_10071769", "reaction_10071630", "reaction_10071767", "reaction_10071622", "reaction_10071638", "reaction_10071640", "reaction_10071607" ] }, "R-BTA-432030": { "id": "pathway_10093746", "reactome": "R-BTA-432030", "name": "Transport of glycerol from adipocytes to the liver by Aquaporins", "reactions": [ "reaction_10049271" ] }, "R-BTA-186797": { "id": "pathway_10093554", "reactome": "R-BTA-186797", "name": "Signaling by PDGF", "reactions": [ "reaction_10046666", "reaction_10046660", "reaction_10046677", "reaction_10091689" ] }, "R-BTA-373752": { "id": "pathway_10093524", "reactome": "R-BTA-373752", "name": "Netrin-1 signaling", "reactions": [ "reaction_10045509" ] }, "R-BTA-5654733": { "id": "pathway_10093912", "reactome": "R-BTA-5654733", "name": "Negative regulation of FGFR4 signaling", "reactions": [ "reaction_10073246", "reaction_10057327", "reaction_10057318", "reaction_10073222", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-5621481": { "id": "pathway_10094472", "reactome": "R-BTA-5621481", "name": "C-type lectin receptors (CLRs)", "reactions": [ "reaction_10072006", "reaction_10072061", "reaction_10072364", "reaction_10072011", "reaction_10072032", "reaction_10072015", "reaction_10071948", "reaction_10072388", "reaction_10072030", "reaction_10071975", "reaction_10084636", "reaction_10071982", "reaction_10072045", "reaction_10072022", "reaction_10072053", "reaction_10072383", "reaction_10072057", "reaction_10072392", "reaction_10072374", "reaction_10072002", "reaction_10072395" ] }, "R-BTA-8963743": { "id": "pathway_10093164", "reactome": "R-BTA-8963743", "name": "Digestion and absorption", "reactions": [ "reaction_10041239", "reaction_10086435", "reaction_10040866", "reaction_10041241", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10086248", "reaction_10088973", "reaction_10086350", "reaction_10073378", "reaction_10040608", "reaction_10054375", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-2408522": { "id": "pathway_10094288", "reactome": "R-BTA-2408522", "name": "Selenoamino acid metabolism", "reactions": [ "reaction_10065455" ] }, "R-BTA-2173782": { "id": "pathway_10094264", "reactome": "R-BTA-2173782", "name": "Binding and Uptake of Ligands by Scavenger Receptors", "reactions": [ "reaction_10065163", "reaction_10065173", "reaction_10064753", "reaction_10064757", "reaction_10064765" ] }, "R-BTA-8963896": { "id": "pathway_10094578", "reactome": "R-BTA-8963896", "name": "HDL assembly", "reactions": [ "reaction_10074486", "reaction_10074474" ] }, "R-BTA-71384": { "id": "pathway_10092558", "reactome": "R-BTA-71384", "name": "Ethanol oxidation", "reactions": [ "reaction_10076144", "reaction_10034175", "reaction_10034231", "reaction_10034206", "reaction_10034215", "reaction_10050160" ] }, "R-BTA-8848021": { "id": "pathway_10094724", "reactome": "R-BTA-8848021", "name": "Signaling by PTK6", "reactions": [ "reaction_10083646", "reaction_10083695", "reaction_10083697", "reaction_10083487", "reaction_10083707", "reaction_10083676", "reaction_10083726", "reaction_10083672", "reaction_10083581", "reaction_10083729", "reaction_10083638", "reaction_10083652", "reaction_10083656", "reaction_10084466", "reaction_10083558", "reaction_10083588", "reaction_10083632", "reaction_10083664", "reaction_10083477", "reaction_10083690", "reaction_10083629", "reaction_10083565", "reaction_10083684", "reaction_10083483", "reaction_10083622" ] }, "R-BTA-5205647": { "id": "pathway_10094420", "reactome": "R-BTA-5205647", "name": "Mitophagy", "reactions": [ "reaction_10070261", "reaction_10087615", "reaction_10088891", "reaction_10070265", "reaction_10070259", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-2514853": { "id": "pathway_10094302", "reactome": "R-BTA-2514853", "name": "Condensation of Prometaphase Chromosomes", "reactions": [ "reaction_10065794" ] }, "R-BTA-9615933": { "id": "pathway_10095002", "reactome": "R-BTA-9615933", "name": "Postmitotic nuclear pore complex (NPC) reformation", "reactions": [ "reaction_10091141", "reaction_10091145" ] }, "R-BTA-139910": { "id": "pathway_10092860", "reactome": "R-BTA-139910", "name": "Activation of BMF and translocation to mitochondria", "reactions": [ "reaction_10037702", "reaction_10037706" ] }, "R-BTA-1369007": { "id": "pathway_10093558", "reactome": "R-BTA-1369007", "name": "Mitochondrial ABC transporters", "reactions": [ "reaction_10057832", "reaction_10046698" ] }, "R-BTA-77310": { "id": "pathway_10092704", "reactome": "R-BTA-77310", "name": "Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA", "reactions": [ "reaction_10036021", "reaction_10036012" ] }, "R-BTA-3371556": { "id": "pathway_10094362", "reactome": "R-BTA-3371556", "name": "Cellular response to heat stress", "reactions": [ "reaction_10071208", "reaction_10071127", "reaction_10068008", "reaction_10067993", "reaction_10071313", "reaction_10071241" ] }, "R-BTA-8982491": { "id": "pathway_10092454", "reactome": "R-BTA-8982491", "name": "Glycogen metabolism", "reactions": [ "reaction_10068755", "reaction_10067610", "reaction_10034118", "reaction_10067644", "reaction_10068752", "reaction_10050637", "reaction_10067634", "reaction_10034138", "reaction_10090696", "reaction_10067648", "reaction_10033594", "reaction_10067639", "reaction_10067622", "reaction_10068748" ] }, "R-BTA-9018678": { "id": "pathway_10094240", "reactome": "R-BTA-9018678", "name": "Biosynthesis of specialized proresolving mediators (SPMs)", "reactions": [ "reaction_10090491", "reaction_10064491", "reaction_10090374", "reaction_10090440", "reaction_10090708", "reaction_10090394", "reaction_10090384", "reaction_10090472", "reaction_10090466", "reaction_10064500", "reaction_10090388", "reaction_10090506", "reaction_10090390", "reaction_10090508", "reaction_10090489", "reaction_10090480", "reaction_10090386", "reaction_10090458", "reaction_10090460", "reaction_10090396", "reaction_10090477", "reaction_10090504", "reaction_10090392", "reaction_10090382", "reaction_10090377", "reaction_10090474", "reaction_10090498", "reaction_10090510", "reaction_10090470", "reaction_10090464", "reaction_10090379", "reaction_10090468", "reaction_10090462" ] }, "R-BTA-1489509": { "id": "pathway_10092790", "reactome": "R-BTA-1489509", "name": "DAG and IP3 signaling", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981", "reaction_10041863" ] }, "R-BTA-375276": { "id": "pathway_10093500", "reactome": "R-BTA-375276", "name": "Peptide ligand-binding receptors", "reactions": [ "reaction_10045324", "reaction_10049645", "reaction_10046917", "reaction_10049683", "reaction_10045406", "reaction_10049637", "reaction_10045384", "reaction_10045196", "reaction_10045180", "reaction_10046733", "reaction_10046731", "reaction_10045072", "reaction_10049570", "reaction_10045292", "reaction_10049639", "reaction_10049699", "reaction_10046919", "reaction_10046953", "reaction_10046729", "reaction_10045268", "reaction_10046735", "reaction_10047483", "reaction_10053335", "reaction_10091037", "reaction_10067358", "reaction_10046915", "reaction_10046763", "reaction_10045362", "reaction_10045350", "reaction_10049520", "reaction_10046773", "reaction_10049661", "reaction_10054775", "reaction_10045168", "reaction_10083880", "reaction_10045332", "reaction_10045156", "reaction_10045094", "reaction_10045106", "reaction_10045280" ] }, "R-BTA-1799339": { "id": "pathway_10094164", "reactome": "R-BTA-1799339", "name": "SRP-dependent cotranslational protein targeting to membrane", "reactions": [ "reaction_10060894" ] }, "R-BTA-428559": { "id": "pathway_10093520", "reactome": "R-BTA-428559", "name": "Proton-coupled neutral amino acid transporters", "reactions": [ "reaction_10045473" ] }, "R-BTA-5654738": { "id": "pathway_10093184", "reactome": "R-BTA-5654738", "name": "Signaling by FGFR2", "reactions": [ "reaction_10073129", "reaction_10072979", "reaction_10057327", "reaction_10072929", "reaction_10040788", "reaction_10072993", "reaction_10040744", "reaction_10073208", "reaction_10040785", "reaction_10073127", "reaction_10072976", "reaction_10057314", "reaction_10057329", "reaction_10073242", "reaction_10059156", "reaction_10053082", "reaction_10073004", "reaction_10073133", "reaction_10057318", "reaction_10072999", "reaction_10072909", "reaction_10073001", "reaction_10087370", "reaction_10040720", "reaction_10072931", "reaction_10073328", "reaction_10073231", "reaction_10073136", "reaction_10057323", "reaction_10057337", "reaction_10057302" ] }, "R-BTA-190322": { "id": "pathway_10093196", "reactome": "R-BTA-190322", "name": "FGFR4 ligand binding and activation", "reactions": [ "reaction_10057704", "reaction_10057707", "reaction_10040776", "reaction_10040769" ] }, "R-BTA-416482": { "id": "pathway_10092836", "reactome": "R-BTA-416482", "name": "G alpha (12/13) signalling events", "reactions": [ "reaction_10037332", "reaction_10047956", "reaction_10047552", "reaction_10048170", "reaction_10051667", "reaction_10037330" ] }, "R-BTA-180336": { "id": "pathway_10093134", "reactome": "R-BTA-180336", "name": "SHC1 events in EGFR signaling", "reactions": [ "reaction_10040286", "reaction_10040331", "reaction_10040303", "reaction_10040258" ] }, "R-BTA-5578768": { "id": "pathway_10094462", "reactome": "R-BTA-5578768", "name": "Physiological factors", "reactions": [ "reaction_10071843", "reaction_10077468" ] }, "R-BTA-947581": { "id": "pathway_10093916", "reactome": "R-BTA-947581", "name": "Molybdenum cofactor biosynthesis", "reactions": [ "reaction_10053298", "reaction_10053287", "reaction_10053266" ] }, "R-BTA-606279": { "id": "pathway_10093836", "reactome": "R-BTA-606279", "name": "Deposition of new CENPA-containing nucleosomes at the centromere", "reactions": [ "reaction_10051465", "reaction_10051461", "reaction_10051451", "reaction_10051463" ] }, "R-BTA-964827": { "id": "pathway_10093918", "reactome": "R-BTA-964827", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2", "reactions": [ "reaction_10053339", "reaction_10053317", "reaction_10053337" ] }, "R-BTA-901042": { "id": "pathway_10093954", "reactome": "R-BTA-901042", "name": "Calnexin/calreticulin cycle", "reactions": [ "reaction_10056058" ] }, "R-BTA-549127": { "id": "pathway_10093830", "reactome": "R-BTA-549127", "name": "Organic cation transport", "reactions": [ "reaction_10051283", "reaction_10051307", "reaction_10051325", "reaction_10051286", "reaction_10051269", "reaction_10051276" ] }, "R-BTA-3299685": { "id": "pathway_10092550", "reactome": "R-BTA-3299685", "name": "Detoxification of Reactive Oxygen Species", "reactions": [ "reaction_10067375", "reaction_10067416", "reaction_10056408", "reaction_10067731", "reaction_10067735", "reaction_10067744", "reaction_10034166", "reaction_10067388", "reaction_10068575", "reaction_10067722", "reaction_10080786", "reaction_10068716", "reaction_10087866", "reaction_10067398", "reaction_10069854", "reaction_10076891", "reaction_10068578" ] }, "R-BTA-187577": { "id": "pathway_10093154", "reactome": "R-BTA-187577", "name": "SCF(Skp2)-mediated degradation of p27/p21", "reactions": [ "reaction_10040542", "reaction_10040521", "reaction_10083565", "reaction_10083558" ] }, "R-BTA-418990": { "id": "pathway_10093686", "reactome": "R-BTA-418990", "name": "Adherens junctions interactions", "reactions": [ "reaction_10048352", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-8866427": { "id": "pathway_10094768", "reactome": "R-BTA-8866427", "name": "VLDLR internalisation and degradation", "reactions": [ "reaction_10084300" ] }, "R-BTA-5654716": { "id": "pathway_10094520", "reactome": "R-BTA-5654716", "name": "Downstream signaling of activated FGFR4", "reactions": [ "reaction_10073237", "reaction_10073047", "reaction_10073184", "reaction_10073044", "reaction_10073177", "reaction_10073175", "reaction_10072939", "reaction_10073028", "reaction_10073037", "reaction_10072927", "reaction_10073192", "reaction_10073240", "reaction_10073182", "reaction_10072933", "reaction_10087367", "reaction_10073166", "reaction_10073041", "reaction_10073031" ] }, "R-BTA-159763": { "id": "pathway_10092940", "reactome": "R-BTA-159763", "name": "Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus", "reactions": [ "reaction_10038438", "reaction_10038408", "reaction_10038416" ] }, "R-BTA-8964208": { "id": "pathway_10092536", "reactome": "R-BTA-8964208", "name": "Phenylalanine metabolism", "reactions": [ "reaction_10033935", "reaction_10052040", "reaction_10064346", "reaction_10076974" ] }, "R-BTA-1433557": { "id": "pathway_10093394", "reactome": "R-BTA-1433557", "name": "Signaling by SCF-KIT", "reactions": [ "reaction_10057845", "reaction_10091751", "reaction_10057854", "reaction_10091667", "reaction_10057867", "reaction_10058474", "reaction_10043815", "reaction_10058480", "reaction_10057862", "reaction_10057850", "reaction_10043832", "reaction_10058478", "reaction_10057857", "reaction_10057872" ] }, "R-BTA-2142688": { "id": "pathway_10094806", "reactome": "R-BTA-2142688", "name": "Synthesis of 5-eicosatetraenoic acids", "reactions": [ "reaction_10086336" ] }, "R-BTA-8949215": { "id": "pathway_10094836", "reactome": "R-BTA-8949215", "name": "Mitochondrial calcium ion transport", "reactions": [ "reaction_10087646" ] }, "R-BTA-70350": { "id": "pathway_10092460", "reactome": "R-BTA-70350", "name": "Fructose catabolism", "reactions": [ "reaction_10083115", "reaction_10033570", "reaction_10033561" ] }, "R-BTA-446388": { "id": "pathway_10093750", "reactome": "R-BTA-446388", "name": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components", "reactions": [ "reaction_10049891", "reaction_10049312", "reaction_10049883" ] }, "R-BTA-937061": { "id": "pathway_10093070", "reactome": "R-BTA-937061", "name": "TRIF(TICAM1)-mediated TLR4 signaling ", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-189483": { "id": "pathway_10092920", "reactome": "R-BTA-189483", "name": "Heme degradation", "reactions": [ "reaction_10038338", "reaction_10091613", "reaction_10040636", "reaction_10038336", "reaction_10091598", "reaction_10091611", "reaction_10091605" ] }, "R-BTA-190828": { "id": "pathway_10093208", "reactome": "R-BTA-190828", "name": "Gap junction trafficking", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040842", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-450385": { "id": "pathway_10093806", "reactome": "R-BTA-450385", "name": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA", "reactions": [ "reaction_10050373", "reaction_10051066", "reaction_10050318", "reaction_10050366" ] }, "R-BTA-774815": { "id": "pathway_10093838", "reactome": "R-BTA-774815", "name": "Nucleosome assembly", "reactions": [ "reaction_10051465", "reaction_10051461", "reaction_10051451", "reaction_10051463" ] }, "R-BTA-3371378": { "id": "pathway_10094354", "reactome": "R-BTA-3371378", "name": "Regulation by c-FLIP", "reactions": [ "reaction_10068042", "reaction_10067891", "reaction_10067895", "reaction_10068046" ] }, "R-BTA-9018896": { "id": "pathway_10094906", "reactome": "R-BTA-9018896", "name": "Biosynthesis of E-series 18(S)-resolvins", "reactions": [ "reaction_10090396", "reaction_10090440", "reaction_10090374" ] }, "R-BTA-15869": { "id": "pathway_10092548", "reactome": "R-BTA-15869", "name": "Metabolism of nucleotides", "reactions": [ "reaction_10088624", "reaction_10036683", "reaction_10083926", "reaction_10065763", "reaction_10051215", "reaction_10035319", "reaction_10036267", "reaction_10035029", "reaction_10034166", "reaction_10035009", "reaction_10036209", "reaction_10036308", "reaction_10036247", "reaction_10035481", "reaction_10065378", "reaction_10036258", "reaction_10036692", "reaction_10034924", "reaction_10036685", "reaction_10083876", "reaction_10034998", "reaction_10051075", "reaction_10034962", "reaction_10035479", "reaction_10035698", "reaction_10036001", "reaction_10036938", "reaction_10082948", "reaction_10035354", "reaction_10065319", "reaction_10065328", "reaction_10065369", "reaction_10065381", "reaction_10036231", "reaction_10035047", "reaction_10035339", "reaction_10065371", "reaction_10065760", "reaction_10035308", "reaction_10083864", "reaction_10077890", "reaction_10083861", "reaction_10035342", "reaction_10065386", "reaction_10034927", "reaction_10034953", "reaction_10065359", "reaction_10034971", "reaction_10036614", "reaction_10083889", "reaction_10035435", "reaction_10036207", "reaction_10035444", "reaction_10035426", "reaction_10035020", "reaction_10034989", "reaction_10035038", "reaction_10036229", "reaction_10035453", "reaction_10034921", "reaction_10083852", "reaction_10036907", "reaction_10083873", "reaction_10065383", "reaction_10035345", "reaction_10035464", "reaction_10091727", "reaction_10035455", "reaction_10088571", "reaction_10036928", "reaction_10036649", "reaction_10036909", "reaction_10035329", "reaction_10065362", "reaction_10036256", "reaction_10034980", "reaction_10036306", "reaction_10035332", "reaction_10035011", "reaction_10035007", "reaction_10036238" ] }, "R-BTA-198933": { "id": "pathway_10093312", "reactome": "R-BTA-198933", "name": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell", "reactions": [ "reaction_10075009", "reaction_10042253", "reaction_10042129", "reaction_10074993", "reaction_10042623", "reaction_10084658", "reaction_10074899", "reaction_10074901", "reaction_10084672", "reaction_10076963", "reaction_10042786", "reaction_10042635" ] }, "R-BTA-1606341": { "id": "pathway_10094206", "reactome": "R-BTA-1606341", "name": "IRF3 mediated activation of type 1 IFN", "reactions": [ "reaction_10065388", "reaction_10063376" ] }, "R-BTA-111453": { "id": "pathway_10092828", "reactome": "R-BTA-111453", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members", "reactions": [ "reaction_10051181", "reaction_10051175", "reaction_10037277" ] }, "R-BTA-5689603": { "id": "pathway_10094618", "reactome": "R-BTA-5689603", "name": "UCH proteinases", "reactions": [ "reaction_10075942" ] }, "R-BTA-8941855": { "id": "pathway_10094802", "reactome": "R-BTA-8941855", "name": "RUNX3 regulates CDKN1A transcription", "reactions": [ "reaction_10088012", "reaction_10086231" ] }, "R-BTA-112316": { "id": "pathway_10092500", "reactome": "R-BTA-112316", "name": "Neuronal System", "reactions": [ "reaction_10078674", "reaction_10046552", "reaction_10051085", "reaction_10078488", "reaction_10083793", "reaction_10046868", "reaction_10078518", "reaction_10033746", "reaction_10039653", "reaction_10081481", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10049090", "reaction_10057639", "reaction_10051989", "reaction_10057607", "reaction_10049583", "reaction_10033755", "reaction_10052013", "reaction_10052018", "reaction_10078566", "reaction_10050517", "reaction_10057399", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10057616", "reaction_10057350", "reaction_10057682", "reaction_10071437", "reaction_10057365", "reaction_10039664", "reaction_10057656", "reaction_10078466", "reaction_10057588", "reaction_10046151", "reaction_10054318", "reaction_10045455", "reaction_10078446", "reaction_10051999", "reaction_10057665", "reaction_10038000", "reaction_10045419", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10054372", "reaction_10045423", "reaction_10045444", "reaction_10088657", "reaction_10078464", "reaction_10057390", "reaction_10036981", "reaction_10051498", "reaction_10044076", "reaction_10044540", "reaction_10078522", "reaction_10090547", "reaction_10084356", "reaction_10057418", "reaction_10078682", "reaction_10044086", "reaction_10083789", "reaction_10078600", "reaction_10057569", "reaction_10049478", "reaction_10051525", "reaction_10051523", "reaction_10046153", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10045466" ] }, "R-BTA-209968": { "id": "pathway_10093412", "reactome": "R-BTA-209968", "name": "Thyroxine biosynthesis", "reactions": [ "reaction_10043956", "reaction_10043978", "reaction_10043980", "reaction_10044828", "reaction_10076360", "reaction_10043986", "reaction_10043924" ] }, "R-BTA-72689": { "id": "pathway_10092582", "reactome": "R-BTA-72689", "name": "Formation of a pool of free 40S subunits", "reactions": [ "reaction_10034855" ] }, "R-BTA-1296346": { "id": "pathway_10094044", "reactome": "R-BTA-1296346", "name": "Tandem pore domain potassium channels", "reactions": [ "reaction_10057665", "reaction_10057616", "reaction_10057682", "reaction_10057656", "reaction_10057639", "reaction_10057588" ] }, "R-BTA-432047": { "id": "pathway_10093828", "reactome": "R-BTA-432047", "name": "Passive transport by Aquaporins", "reactions": [ "reaction_10051148", "reaction_10051145", "reaction_10051150", "reaction_10051143", "reaction_10051141", "reaction_10051136" ] }, "R-BTA-8941413": { "id": "pathway_10094650", "reactome": "R-BTA-8941413", "name": "Events associated with phagocytolytic activity of PMN cells", "reactions": [ "reaction_10084322", "reaction_10077924", "reaction_10086405", "reaction_10077926", "reaction_10077919" ] }, "R-BTA-913709": { "id": "pathway_10093884", "reactome": "R-BTA-913709", "name": "O-linked glycosylation of mucins", "reactions": [ "reaction_10052546", "reaction_10052690", "reaction_10054550", "reaction_10076773", "reaction_10077688", "reaction_10054766", "reaction_10061538", "reaction_10052521", "reaction_10052665", "reaction_10052606", "reaction_10052496", "reaction_10054722", "reaction_10054575", "reaction_10054773", "reaction_10052716", "reaction_10052461" ] }, "R-BTA-9707564": { "id": "pathway_10092972", "reactome": "R-BTA-9707564", "name": "Cytoprotection by HMOX1", "reactions": [ "reaction_10092310", "reaction_10092308", "reaction_10092289", "reaction_10092312", "reaction_10040636", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10038647", "reaction_10092239", "reaction_10092214", "reaction_10047807" ] }, "R-BTA-5218859": { "id": "pathway_10092826", "reactome": "R-BTA-5218859", "name": "Regulated Necrosis", "reactions": [ "reaction_10092350", "reaction_10092354", "reaction_10091773", "reaction_10091439", "reaction_10091806", "reaction_10068030", "reaction_10070534", "reaction_10037253", "reaction_10074254", "reaction_10074240", "reaction_10091409", "reaction_10091779", "reaction_10070684", "reaction_10072346", "reaction_10092358", "reaction_10091793", "reaction_10071534", "reaction_10081905", "reaction_10091808", "reaction_10091425", "reaction_10070682", "reaction_10092341", "reaction_10091810", "reaction_10091783", "reaction_10070689", "reaction_10091429", "reaction_10070531", "reaction_10091415", "reaction_10092352", "reaction_10091423", "reaction_10092356" ] }, "R-BTA-9013700": { "id": "pathway_10094974", "reactome": "R-BTA-9013700", "name": "NOTCH4 Activation and Transmission of Signal to the Nucleus", "reactions": [ "reaction_10090834" ] }, "R-BTA-8983711": { "id": "pathway_10094870", "reactome": "R-BTA-8983711", "name": "OAS antiviral response", "reactions": [ "reaction_10089703", "reaction_10089696", "reaction_10089349", "reaction_10089341" ] }, "R-BTA-392518": { "id": "pathway_10093634", "reactome": "R-BTA-392518", "name": "Signal amplification", "reactions": [ "reaction_10049039", "reaction_10047985", "reaction_10049014", "reaction_10047870", "reaction_10091701", "reaction_10047380", "reaction_10047857", "reaction_10047475", "reaction_10049035" ] }, "R-BTA-179812": { "id": "pathway_10092738", "reactome": "R-BTA-179812", "name": "GRB2 events in EGFR signaling", "reactions": [ "reaction_10040317", "reaction_10040326", "reaction_10036616" ] }, "R-BTA-3065679": { "id": "pathway_10094322", "reactome": "R-BTA-3065679", "name": "SUMO is proteolytically processed", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-73887": { "id": "pathway_10092532", "reactome": "R-BTA-73887", "name": "Death Receptor Signalling", "reactions": [ "reaction_10071556", "reaction_10041333", "reaction_10092026", "reaction_10035726", "reaction_10043778", "reaction_10043739", "reaction_10036148", "reaction_10084723", "reaction_10036146", "reaction_10043744", "reaction_10043753", "reaction_10071534", "reaction_10037964", "reaction_10071526", "reaction_10071524", "reaction_10033926", "reaction_10092031", "reaction_10071541", "reaction_10041470", "reaction_10043877", "reaction_10067908", "reaction_10067895" ] }, "R-BTA-71403": { "id": "pathway_10092514", "reactome": "R-BTA-71403", "name": "Citric acid cycle (TCA cycle)", "reactions": [ "reaction_10089782", "reaction_10050446", "reaction_10050437", "reaction_10089795", "reaction_10089808", "reaction_10033868" ] }, "R-BTA-427975": { "id": "pathway_10093724", "reactome": "R-BTA-427975", "name": "Proton/oligopeptide cotransporters", "reactions": [ "reaction_10048802", "reaction_10048795" ] }, "R-BTA-1855167": { "id": "pathway_10094174", "reactome": "R-BTA-1855167", "name": "Synthesis of pyrophosphates in the cytosol", "reactions": [ "reaction_10061116", "reaction_10060956", "reaction_10061037", "reaction_10060980", "reaction_10063018", "reaction_10061125", "reaction_10061011", "reaction_10061079", "reaction_10061040", "reaction_10063020", "reaction_10061034", "reaction_10061024", "reaction_10060983" ] }, "R-BTA-73929": { "id": "pathway_10092752", "reactome": "R-BTA-73929", "name": "Base-Excision Repair, AP Site Formation", "reactions": [ "reaction_10036716", "reaction_10091566", "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036767", "reaction_10036709", "reaction_10091211", "reaction_10036729", "reaction_10036798", "reaction_10036736", "reaction_10091233", "reaction_10091240", "reaction_10036743", "reaction_10036805" ] }, "R-BTA-6804115": { "id": "pathway_10094664", "reactome": "R-BTA-6804115", "name": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "reactions": [ "reaction_10081380", "reaction_10078658" ] }, "R-BTA-69002": { "id": "pathway_10092400", "reactome": "R-BTA-69002", "name": "DNA Replication Pre-Initiation", "reactions": [ "reaction_10033379", "reaction_10033412", "reaction_10033512", "reaction_10033466" ] }, "R-BTA-190377": { "id": "pathway_10093186", "reactome": "R-BTA-190377", "name": "FGFR2b ligand binding and activation", "reactions": [ "reaction_10073328", "reaction_10040744", "reaction_10040785" ] }, "R-BTA-73854": { "id": "pathway_10092600", "reactome": "R-BTA-73854", "name": "RNA Polymerase I Promoter Clearance", "reactions": [ "reaction_10035301", "reaction_10035254" ] }, "R-BTA-9024446": { "id": "pathway_10094924", "reactome": "R-BTA-9024446", "name": "NR1H2 and NR1H3-mediated signaling", "reactions": [ "reaction_10090456", "reaction_10090563", "reaction_10090567", "reaction_10090571", "reaction_10090452", "reaction_10090559", "reaction_10090555" ] }, "R-BTA-3322077": { "id": "pathway_10092452", "reactome": "R-BTA-3322077", "name": "Glycogen synthesis", "reactions": [ "reaction_10068755", "reaction_10067610", "reaction_10067644", "reaction_10068752", "reaction_10067634", "reaction_10067648", "reaction_10067639", "reaction_10067622", "reaction_10068748" ] }, "R-BTA-110331": { "id": "pathway_10092756", "reactome": "R-BTA-110331", "name": "Cleavage of the damaged purine", "reactions": [ "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036798", "reaction_10091233", "reaction_10091240", "reaction_10036805" ] }, "R-BTA-8943724": { "id": "pathway_10094828", "reactome": "R-BTA-8943724", "name": "Regulation of PTEN gene transcription", "reactions": [ "reaction_10087531" ] }, "R-BTA-166663": { "id": "pathway_10093020", "reactome": "R-BTA-166663", "name": "Initial triggering of complement", "reactions": [ "reaction_10039782", "reaction_10039465", "reaction_10054736", "reaction_10039778" ] }, "R-BTA-373760": { "id": "pathway_10093508", "reactome": "R-BTA-373760", "name": "L1CAM interactions", "reactions": [ "reaction_10045224" ] }, "R-BTA-167827": { "id": "pathway_10093084", "reactome": "R-BTA-167827", "name": "The proton buffering model", "reactions": [ "reaction_10039604" ] }, "R-BTA-8951664": { "id": "pathway_10094616", "reactome": "R-BTA-8951664", "name": "Neddylation", "reactions": [ "reaction_10088688", "reaction_10087883", "reaction_10088734", "reaction_10087852", "reaction_10088787", "reaction_10087848", "reaction_10075942", "reaction_10087825", "reaction_10087885", "reaction_10088807", "reaction_10087993" ] }, "R-BTA-9615017": { "id": "pathway_10094986", "reactome": "R-BTA-9615017", "name": "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes", "reactions": [ "reaction_10091049" ] }, "R-BTA-9026766": { "id": "pathway_10094940", "reactome": "R-BTA-9026766", "name": "Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)", "reactions": [ "reaction_10090491" ] }, "R-BTA-8964572": { "id": "pathway_10094770", "reactome": "R-BTA-8964572", "name": "Lipid particle organization", "reactions": [ "reaction_10084424", "reaction_10084694", "reaction_10084480" ] }, "R-BTA-964975": { "id": "pathway_10093922", "reactome": "R-BTA-964975", "name": "Vitamins B6 activation to pyridoxal phosphate", "reactions": [ "reaction_10053361", "reaction_10053352", "reaction_10053350", "reaction_10053363", "reaction_10053348", "reaction_10066619" ] }, "R-BTA-450520": { "id": "pathway_10093802", "reactome": "R-BTA-450520", "name": "HuR (ELAVL1) binds and stabilizes mRNA", "reactions": [ "reaction_10050306", "reaction_10051219", "reaction_10050378", "reaction_10051221", "reaction_10050368", "reaction_10050400" ] }, "R-BTA-420597": { "id": "pathway_10093696", "reactome": "R-BTA-420597", "name": "Nectin/Necl trans heterodimerization", "reactions": [ "reaction_10048334", "reaction_10048342", "reaction_10048352" ] }, "R-BTA-9026286": { "id": "pathway_10094930", "reactome": "R-BTA-9026286", "name": "Biosynthesis of DPAn-3-derived protectins and resolvins", "reactions": [ "reaction_10090470" ] }, "R-BTA-2179392": { "id": "pathway_10094268", "reactome": "R-BTA-2179392", "name": "EGFR Transactivation by Gastrin", "reactions": [ "reaction_10064919", "reaction_10064915", "reaction_10064910" ] }, "R-BTA-166058": { "id": "pathway_10093038", "reactome": "R-BTA-166058", "name": "MyD88:MAL(TIRAP) cascade initiated on plasma membrane", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1630316": { "id": "pathway_10093122", "reactome": "R-BTA-1630316", "name": "Glycosaminoglycan metabolism", "reactions": [ "reaction_10061395", "reaction_10062984", "reaction_10064595", "reaction_10063520", "reaction_10061642", "reaction_10039887", "reaction_10063249", "reaction_10063510", "reaction_10061350", "reaction_10063610", "reaction_10060293", "reaction_10061651", "reaction_10060685", "reaction_10062697", "reaction_10060741", "reaction_10063801", "reaction_10060827", "reaction_10061612", "reaction_10091291", "reaction_10060295", "reaction_10063010", "reaction_10063803", "reaction_10060671", "reaction_10062655", "reaction_10063216", "reaction_10064355", "reaction_10039890", "reaction_10064593", "reaction_10091293", "reaction_10048727", "reaction_10064393", "reaction_10060678", "reaction_10063807", "reaction_10063477", "reaction_10051589", "reaction_10060825", "reaction_10060634", "reaction_10060842", "reaction_10060625", "reaction_10060031", "reaction_10063485", "reaction_10062701", "reaction_10063232", "reaction_10091289", "reaction_10063805", "reaction_10061402", "reaction_10063508", "reaction_10060285", "reaction_10063014", "reaction_10061251", "reaction_10063633", "reaction_10064353", "reaction_10062508", "reaction_10063530", "reaction_10064597", "reaction_10051570", "reaction_10060829", "reaction_10062463", "reaction_10063022", "reaction_10063603", "reaction_10063586", "reaction_10062674", "reaction_10063532", "reaction_10091286", "reaction_10064391" ] }, "R-BTA-2995410": { "id": "pathway_10095000", "reactome": "R-BTA-2995410", "name": "Nuclear Envelope (NE) Reassembly", "reactions": [ "reaction_10091634", "reaction_10091145", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-6804758": { "id": "pathway_10094336", "reactome": "R-BTA-6804758", "name": "Regulation of TP53 Activity through Acetylation", "reactions": [ "reaction_10082931", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10083077", "reaction_10083072", "reaction_10082923", "reaction_10082934", "reaction_10072550" ] }, "R-BTA-379716": { "id": "pathway_10092566", "reactome": "R-BTA-379716", "name": "Cytosolic tRNA aminoacylation", "reactions": [ "reaction_10034224" ] }, "R-BTA-2022854": { "id": "pathway_10093850", "reactome": "R-BTA-2022854", "name": "Keratan sulfate biosynthesis", "reactions": [ "reaction_10063530", "reaction_10063485", "reaction_10063520", "reaction_10063232", "reaction_10063249", "reaction_10063508", "reaction_10063532", "reaction_10063477", "reaction_10051589" ] }, "R-BTA-5654700": { "id": "pathway_10094524", "reactome": "R-BTA-5654700", "name": "FRS-mediated FGFR2 signaling", "reactions": [ "reaction_10073133", "reaction_10073127", "reaction_10087370", "reaction_10073129", "reaction_10072979", "reaction_10072976", "reaction_10073136" ] }, "R-BTA-1638091": { "id": "pathway_10093856", "reactome": "R-BTA-1638091", "name": "Heparan sulfate/heparin (HS-GAG) metabolism", "reactions": [ "reaction_10062984", "reaction_10061395", "reaction_10063610", "reaction_10060685", "reaction_10061350", "reaction_10060741", "reaction_10063801", "reaction_10063010", "reaction_10063803", "reaction_10060671", "reaction_10063216", "reaction_10060678", "reaction_10060634", "reaction_10051589", "reaction_10060625", "reaction_10063805", "reaction_10061402", "reaction_10063633", "reaction_10061251", "reaction_10063022", "reaction_10063603", "reaction_10063586", "reaction_10091286" ] }, "R-BTA-6796648": { "id": "pathway_10094662", "reactome": "R-BTA-6796648", "name": "TP53 Regulates Transcription of DNA Repair Genes", "reactions": [ "reaction_10078474" ] }, "R-BTA-9716542": { "id": "pathway_10093370", "reactome": "R-BTA-9716542", "name": "Signaling by Rho GTPases, Miro GTPases and RHOBTB3", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10092205", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10092203", "reaction_10072515", "reaction_10073503", "reaction_10092208", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] }, "R-BTA-1660516": { "id": "pathway_10094158", "reactome": "R-BTA-1660516", "name": "Synthesis of PIPs at the early endosome membrane", "reactions": [ "reaction_10060574", "reaction_10060558", "reaction_10060588", "reaction_10060518", "reaction_10060614", "reaction_10060501", "reaction_10083800" ] }, "R-BTA-446652": { "id": "pathway_10093400", "reactome": "R-BTA-446652", "name": "Interleukin-1 family signaling", "reactions": [ "reaction_10050028", "reaction_10083537", "reaction_10089591", "reaction_10089843", "reaction_10089615", "reaction_10089625", "reaction_10050428", "reaction_10083522", "reaction_10050420", "reaction_10091757", "reaction_10089597", "reaction_10050011", "reaction_10051095", "reaction_10043867", "reaction_10089812", "reaction_10089595", "reaction_10089819", "reaction_10089621", "reaction_10049721", "reaction_10050024", "reaction_10087338" ] }, "R-BTA-1592230": { "id": "pathway_10094610", "reactome": "R-BTA-1592230", "name": "Mitochondrial biogenesis", "reactions": [ "reaction_10087635", "reaction_10075362", "reaction_10075350" ] }, "R-BTA-977443": { "id": "pathway_10093098", "reactome": "R-BTA-977443", "name": "GABA receptor activation", "reactions": [ "reaction_10039653", "reaction_10054361", "reaction_10039676", "reaction_10054372", "reaction_10039651", "reaction_10039664" ] }, "R-BTA-525793": { "id": "pathway_10093794", "reactome": "R-BTA-525793", "name": "Myogenesis", "reactions": [ "reaction_10050085", "reaction_10050116" ] }, "R-BTA-1632852": { "id": "pathway_10094424", "reactome": "R-BTA-1632852", "name": "Macroautophagy", "reactions": [ "reaction_10070261", "reaction_10073831", "reaction_10074142", "reaction_10074302", "reaction_10090398", "reaction_10087615", "reaction_10074415", "reaction_10073835", "reaction_10074381", "reaction_10074365", "reaction_10074507", "reaction_10074659", "reaction_10070265", "reaction_10070259", "reaction_10088891", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-76005": { "id": "pathway_10093738", "reactome": "R-BTA-76005", "name": "Response to elevated platelet cytosolic Ca2+", "reactions": [ "reaction_10050994", "reaction_10051062", "reaction_10050948", "reaction_10050870", "reaction_10051002", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-916853": { "id": "pathway_10093876", "reactome": "R-BTA-916853", "name": "Degradation of GABA", "reactions": [ "reaction_10051989" ] }, "R-BTA-163841": { "id": "pathway_10092944", "reactome": "R-BTA-163841", "name": "Gamma carboxylation, hypusine formation and arylsulfatase activation", "reactions": [ "reaction_10091630", "reaction_10071566", "reaction_10038408", "reaction_10060109", "reaction_10038416", "reaction_10077883", "reaction_10071579", "reaction_10043717", "reaction_10038438", "reaction_10043698", "reaction_10077897" ] }, "R-BTA-5654732": { "id": "pathway_10093906", "reactome": "R-BTA-5654732", "name": "Negative regulation of FGFR3 signaling", "reactions": [ "reaction_10057327", "reaction_10057318", "reaction_10073244", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10073215", "reaction_10057302" ] }, "R-BTA-190374": { "id": "pathway_10093200", "reactome": "R-BTA-190374", "name": "FGFR1c and Klotho ligand binding and activation", "reactions": [ "reaction_10040860", "reaction_10040773" ] }, "R-BTA-5423646": { "id": "pathway_10092904", "reactome": "R-BTA-5423646", "name": "Aflatoxin activation and detoxification", "reactions": [ "reaction_10071722", "reaction_10071712", "reaction_10071715", "reaction_10071729", "reaction_10071727", "reaction_10038060", "reaction_10071717", "reaction_10071763", "reaction_10071754" ] }, "R-BTA-1236977": { "id": "pathway_10093996", "reactome": "R-BTA-1236977", "name": "Endosomal/Vacuolar pathway", "reactions": [ "reaction_10056914", "reaction_10056903", "reaction_10056910" ] }, "R-BTA-194002": { "id": "pathway_10093252", "reactome": "R-BTA-194002", "name": "Glucocorticoid biosynthesis", "reactions": [ "reaction_10041412", "reaction_10041395", "reaction_10041721", "reaction_10057880", "reaction_10041424", "reaction_10041379", "reaction_10041284" ] }, "R-BTA-71737": { "id": "pathway_10092564", "reactome": "R-BTA-71737", "name": "Pyrophosphate hydrolysis", "reactions": [ "reaction_10050169", "reaction_10034224" ] }, "R-BTA-1482925": { "id": "pathway_10094094", "reactome": "R-BTA-1482925", "name": "Acyl chain remodelling of PG", "reactions": [ "reaction_10059847", "reaction_10058877", "reaction_10058934", "reaction_10059018", "reaction_10058812", "reaction_10059021", "reaction_10058826", "reaction_10059016", "reaction_10058983", "reaction_10058913" ] } }, "collapsed_pathway_dictionary": { "R-BTA-9020591": { "id": "pathway_10094838", "reactome": "R-BTA-9020591", "name": "Interleukin-12 signaling", "reactions": [ "reaction_10087732", "reaction_10087650", "reaction_10087663", "reaction_10087795", "reaction_10088519" ] }, "R-BTA-112311": { "id": "pathway_10092886", "reactome": "R-BTA-112311", "name": "Neurotransmitter clearance", "reactions": [ "reaction_10046552", "reaction_10038000", "reaction_10045423", "reaction_10046153", "reaction_10088657", "reaction_10046151" ] }, "R-BTA-6791312": { "id": "pathway_10094658", "reactome": "R-BTA-6791312", "name": "TP53 Regulates Transcription of Cell Cycle Genes", "reactions": [ "reaction_10081380", "reaction_10078658", "reaction_10081499", "reaction_10077955", "reaction_10088534", "reaction_10088546", "reaction_10088542", "reaction_10078349" ] }, "R-BTA-196071": { "id": "pathway_10093248", "reactome": "R-BTA-196071", "name": "Metabolism of steroid hormones", "reactions": [ "reaction_10041293", "reaction_10041721", "reaction_10041297", "reaction_10041716", "reaction_10041412", "reaction_10050650", "reaction_10041386", "reaction_10077113", "reaction_10041692", "reaction_10041415", "reaction_10041424", "reaction_10041379", "reaction_10041284", "reaction_10092062", "reaction_10041397", "reaction_10092065", "reaction_10084679", "reaction_10041719", "reaction_10041295", "reaction_10041269", "reaction_10041395", "reaction_10057880", "reaction_10041290", "reaction_10041684", "reaction_10041393", "reaction_10041277", "reaction_10076281", "reaction_10041299", "reaction_10051676" ] }, "R-BTA-71406": { "id": "pathway_10092480", "reactome": "R-BTA-71406", "name": "Pyruvate metabolism and Citric Acid (TCA) cycle", "reactions": [ "reaction_10089782", "reaction_10051980", "reaction_10089721", "reaction_10034240", "reaction_10051973", "reaction_10076468", "reaction_10050446", "reaction_10089808", "reaction_10089728", "reaction_10089795", "reaction_10050437", "reaction_10033868", "reaction_10033671" ] }, "R-BTA-9612973": { "id": "pathway_10094426", "reactome": "R-BTA-9612973", "name": "Autophagy", "reactions": [ "reaction_10070261", "reaction_10073831", "reaction_10074142", "reaction_10074302", "reaction_10090398", "reaction_10087615", "reaction_10074415", "reaction_10073835", "reaction_10074381", "reaction_10074365", "reaction_10074507", "reaction_10074659", "reaction_10070265", "reaction_10070259", "reaction_10088891", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-451306": { "id": "pathway_10093814", "reactome": "R-BTA-451306", "name": "Ionotropic activity of kainate receptors", "reactions": [ "reaction_10050514", "reaction_10050517" ] }, "R-BTA-181430": { "id": "pathway_10093514", "reactome": "R-BTA-181430", "name": "Norepinephrine Neurotransmitter Release Cycle", "reactions": [ "reaction_10045419", "reaction_10045421" ] }, "R-BTA-168176": { "id": "pathway_10093034", "reactome": "R-BTA-168176", "name": "Toll Like Receptor 5 (TLR5) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-3928663": { "id": "pathway_10094396", "reactome": "R-BTA-3928663", "name": "EPHA-mediated growth cone collapse", "reactions": [ "reaction_10069253" ] }, "R-BTA-6788467": { "id": "pathway_10094634", "reactome": "R-BTA-6788467", "name": "IL-6-type cytokine receptor ligand interactions", "reactions": [ "reaction_10077455", "reaction_10077422", "reaction_10077424" ] }, "R-BTA-2172127": { "id": "pathway_10094292", "reactome": "R-BTA-2172127", "name": "DAP12 interactions", "reactions": [ "reaction_10065517", "reaction_10065491" ] }, "R-BTA-190704": { "id": "pathway_10093216", "reactome": "R-BTA-190704", "name": "Oligomerization of connexins into connexons", "reactions": [ "reaction_10040851" ] }, "R-BTA-114608": { "id": "pathway_10093736", "reactome": "R-BTA-114608", "name": "Platelet degranulation ", "reactions": [ "reaction_10050994", "reaction_10051062", "reaction_10050948", "reaction_10050870", "reaction_10051002", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-9013420": { "id": "pathway_10094902", "reactome": "R-BTA-9013420", "name": "RHOU GTPase cycle", "reactions": [ "reaction_10090311", "reaction_10090306" ] }, "R-BTA-446210": { "id": "pathway_10093776", "reactome": "R-BTA-446210", "name": "Synthesis of UDP-N-acetyl-glucosamine", "reactions": [ "reaction_10081497", "reaction_10081490", "reaction_10049778", "reaction_10050153" ] }, "R-BTA-4608870": { "id": "pathway_10094402", "reactome": "R-BTA-4608870", "name": "Asymmetric localization of PCP proteins", "reactions": [ "reaction_10069872", "reaction_10069593", "reaction_10069595" ] }, "R-BTA-211979": { "id": "pathway_10093432", "reactome": "R-BTA-211979", "name": "Eicosanoids", "reactions": [ "reaction_10071909", "reaction_10044480", "reaction_10044151" ] }, "R-BTA-5654719": { "id": "pathway_10094532", "reactome": "R-BTA-5654719", "name": "SHC-mediated cascade:FGFR4", "reactions": [ "reaction_10073044", "reaction_10073037", "reaction_10073041", "reaction_10073047" ] }, "R-BTA-75109": { "id": "pathway_10092672", "reactome": "R-BTA-75109", "name": "Triglyceride biosynthesis", "reactions": [ "reaction_10035795", "reaction_10080887", "reaction_10035838", "reaction_10076847", "reaction_10035829" ] }, "R-BTA-1912408": { "id": "pathway_10094920", "reactome": "R-BTA-1912408", "name": "Pre-NOTCH Transcription and Translation", "reactions": [ "reaction_10090409" ] }, "R-BTA-199992": { "id": "pathway_10093474", "reactome": "R-BTA-199992", "name": "trans-Golgi Network Vesicle Budding", "reactions": [ "reaction_10044826", "reaction_10045538" ] }, "R-BTA-500753": { "id": "pathway_10092584", "reactome": "R-BTA-500753", "name": "Pyrimidine biosynthesis", "reactions": [ "reaction_10034924", "reaction_10034921", "reaction_10034927" ] }, "R-BTA-427589": { "id": "pathway_10093722", "reactome": "R-BTA-427589", "name": "Type II Na+/Pi cotransporters", "reactions": [ "reaction_10048761", "reaction_10048754" ] }, "R-BTA-1474228": { "id": "pathway_10094078", "reactome": "R-BTA-1474228", "name": "Degradation of the extracellular matrix", "reactions": [ "reaction_10059869", "reaction_10064649", "reaction_10076984", "reaction_10059787", "reaction_10059702", "reaction_10059651", "reaction_10059598", "reaction_10059533", "reaction_10064705", "reaction_10087543", "reaction_10059674", "reaction_10059913", "reaction_10059918", "reaction_10058193", "reaction_10058561", "reaction_10065819", "reaction_10065751", "reaction_10087324", "reaction_10059923", "reaction_10068885", "reaction_10059902", "reaction_10059744", "reaction_10060003", "reaction_10059441", "reaction_10059689", "reaction_10059731", "reaction_10059804" ] }, "R-BTA-2029481": { "id": "pathway_10094178", "reactome": "R-BTA-2029481", "name": "FCGR activation", "reactions": [ "reaction_10061174" ] }, "R-BTA-70635": { "id": "pathway_10092488", "reactome": "R-BTA-70635", "name": "Urea cycle", "reactions": [ "reaction_10033690", "reaction_10033770", "reaction_10033706", "reaction_10033697" ] }, "R-BTA-8852135": { "id": "pathway_10094754", "reactome": "R-BTA-8852135", "name": "Protein ubiquitination", "reactions": [ "reaction_10084122", "reaction_10084008", "reaction_10084113", "reaction_10086702", "reaction_10084117", "reaction_10086710" ] }, "R-BTA-375280": { "id": "pathway_10093608", "reactome": "R-BTA-375280", "name": "Amine ligand-binding receptors", "reactions": [ "reaction_10047206", "reaction_10047236", "reaction_10090925", "reaction_10047226", "reaction_10091825", "reaction_10047256", "reaction_10047210", "reaction_10090968", "reaction_10047332", "reaction_10091556", "reaction_10091929", "reaction_10090960", "reaction_10047234", "reaction_10047212", "reaction_10090964", "reaction_10083878", "reaction_10047214", "reaction_10047238", "reaction_10047224", "reaction_10047222" ] }, "R-BTA-2428928": { "id": "pathway_10092648", "reactome": "R-BTA-2428928", "name": "IRS-related events triggered by IGF1R", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-983170": { "id": "pathway_10093378", "reactome": "R-BTA-983170", "name": "Antigen Presentation: Folding, assembly and peptide loading of class I MHC", "reactions": [ "reaction_10055817", "reaction_10054866", "reaction_10055783", "reaction_10055444", "reaction_10055819", "reaction_10055821", "reaction_10055460", "reaction_10043659", "reaction_10087807" ] }, "R-BTA-202040": { "id": "pathway_10093046", "reactome": "R-BTA-202040", "name": "G-protein activation", "reactions": [ "reaction_10039485" ] }, "R-BTA-75108": { "id": "pathway_10092854", "reactome": "R-BTA-75108", "name": "Activation, myristolyation of BID and translocation to mitochondria", "reactions": [ "reaction_10038007", "reaction_10037731", "reaction_10037641", "reaction_10037618" ] }, "R-BTA-444209": { "id": "pathway_10093768", "reactome": "R-BTA-444209", "name": "Free fatty acid receptors", "reactions": [ "reaction_10049585", "reaction_10049615", "reaction_10067360", "reaction_10049617" ] }, "R-BTA-195399": { "id": "pathway_10093262", "reactome": "R-BTA-195399", "name": "VEGF binds to VEGFR leading to receptor dimerization", "reactions": [ "reaction_10041463", "reaction_10041453" ] }, "R-BTA-180292": { "id": "pathway_10093132", "reactome": "R-BTA-180292", "name": "GAB1 signalosome", "reactions": [ "reaction_10040328", "reaction_10040254", "reaction_10040267", "reaction_10040299", "reaction_10040277" ] }, "R-BTA-4641262": { "id": "pathway_10093344", "reactome": "R-BTA-4641262", "name": "Disassembly of the destruction complex and recruitment of AXIN to the membrane", "reactions": [ "reaction_10059152", "reaction_10071320", "reaction_10043129" ] }, "R-BTA-6809371": { "id": "pathway_10094652", "reactome": "R-BTA-6809371", "name": "Formation of the cornified envelope", "reactions": [ "reaction_10083824", "reaction_10083741", "reaction_10083743", "reaction_10083835", "reaction_10077943" ] }, "R-BTA-8857538": { "id": "pathway_10094772", "reactome": "R-BTA-8857538", "name": "PTK6 promotes HIF1A stabilization", "reactions": [ "reaction_10084466" ] }, "R-BTA-9013405": { "id": "pathway_10094890", "reactome": "R-BTA-9013405", "name": "RHOD GTPase cycle", "reactions": [ "reaction_10091916", "reaction_10091884", "reaction_10089985", "reaction_10089972", "reaction_10091902", "reaction_10091878", "reaction_10091896", "reaction_10090009", "reaction_10090011" ] }, "R-BTA-1250347": { "id": "pathway_10094016", "reactome": "R-BTA-1250347", "name": "SHC1 events in ERBB4 signaling", "reactions": [ "reaction_10057177", "reaction_10057175", "reaction_10057191", "reaction_10057188" ] }, "R-BTA-8856688": { "id": "pathway_10094702", "reactome": "R-BTA-8856688", "name": "Golgi-to-ER retrograde transport", "reactions": [ "reaction_10083004", "reaction_10083006", "reaction_10083712", "reaction_10082999" ] }, "R-BTA-446203": { "id": "pathway_10093226", "reactome": "R-BTA-446203", "name": "Asparagine N-linked glycosylation", "reactions": [ "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10077710", "reaction_10053317", "reaction_10076708", "reaction_10076610", "reaction_10069371", "reaction_10077823", "reaction_10056058", "reaction_10054467", "reaction_10082941", "reaction_10069320", "reaction_10049797", "reaction_10069359", "reaction_10054474", "reaction_10049860", "reaction_10076584", "reaction_10053324", "reaction_10069357", "reaction_10049789", "reaction_10081490", "reaction_10049818", "reaction_10054418", "reaction_10049811", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10049867", "reaction_10076696", "reaction_10076635", "reaction_10069368", "reaction_10054438", "reaction_10076586", "reaction_10076736", "reaction_10076706", "reaction_10040933", "reaction_10053337", "reaction_10084373", "reaction_10056061", "reaction_10069373", "reaction_10049858", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10056074", "reaction_10077717", "reaction_10082026", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10053339", "reaction_10076422", "reaction_10054411", "reaction_10077826", "reaction_10076415", "reaction_10049831", "reaction_10083380", "reaction_10049851", "reaction_10049778", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10049844", "reaction_10076778", "reaction_10050153", "reaction_10053331", "reaction_10048958", "reaction_10077816", "reaction_10076698", "reaction_10069382" ] }, "R-BTA-1268020": { "id": "pathway_10094874", "reactome": "R-BTA-1268020", "name": "Mitochondrial protein import", "reactions": [ "reaction_10089391" ] }, "R-BTA-975578": { "id": "pathway_10093926", "reactome": "R-BTA-975578", "name": "Reactions specific to the complex N-glycan synthesis pathway", "reactions": [ "reaction_10076415", "reaction_10077710", "reaction_10077717", "reaction_10076422", "reaction_10054411" ] }, "R-BTA-1236975": { "id": "pathway_10093994", "reactome": "R-BTA-1236975", "name": "Antigen processing-Cross presentation", "reactions": [ "reaction_10056912", "reaction_10056914", "reaction_10056903", "reaction_10056805", "reaction_10056835", "reaction_10056910", "reaction_10084865", "reaction_10084867", "reaction_10056982", "reaction_10087823", "reaction_10057004" ] }, "R-BTA-196836": { "id": "pathway_10093310", "reactome": "R-BTA-196836", "name": "Vitamin C (ascorbate) metabolism", "reactions": [ "reaction_10041955", "reaction_10041962", "reaction_10041975" ] }, "R-BTA-8849468": { "id": "pathway_10094740", "reactome": "R-BTA-8849468", "name": "PTK6 Regulates Proteins Involved in RNA Processing", "reactions": [ "reaction_10083676", "reaction_10083656", "reaction_10083664", "reaction_10083672" ] }, "R-BTA-140180": { "id": "pathway_10092866", "reactome": "R-BTA-140180", "name": "COX reactions", "reactions": [ "reaction_10037751", "reaction_10037748" ] }, "R-BTA-8978868": { "id": "pathway_10092526", "reactome": "R-BTA-8978868", "name": "Fatty acid metabolism", "reactions": [ "reaction_10064516", "reaction_10082880", "reaction_10051252", "reaction_10036220", "reaction_10065216", "reaction_10046992", "reaction_10064565", "reaction_10042860", "reaction_10086336", "reaction_10036038", "reaction_10063430", "reaction_10063442", "reaction_10064506", "reaction_10036029", "reaction_10036040", "reaction_10063444", "reaction_10044657", "reaction_10063425", "reaction_10063428", "reaction_10036218", "reaction_10064442", "reaction_10063570", "reaction_10065225", "reaction_10046984", "reaction_10042961", "reaction_10064521", "reaction_10047001", "reaction_10085185", "reaction_10047058", "reaction_10036021", "reaction_10033912", "reaction_10064465", "reaction_10033896", "reaction_10075607", "reaction_10065213", "reaction_10064567", "reaction_10064482", "reaction_10077784", "reaction_10063420", "reaction_10064452", "reaction_10086403", "reaction_10047042", "reaction_10064479", "reaction_10063440", "reaction_10064546", "reaction_10074353", "reaction_10077835", "reaction_10037751", "reaction_10065210", "reaction_10047044", "reaction_10064554", "reaction_10065223", "reaction_10083389", "reaction_10036025", "reaction_10044599", "reaction_10064474", "reaction_10054592", "reaction_10037748", "reaction_10064578", "reaction_10036042", "reaction_10046989", "reaction_10036664", "reaction_10063452", "reaction_10076382", "reaction_10063413", "reaction_10036027", "reaction_10063446", "reaction_10047056", "reaction_10063437", "reaction_10036012", "reaction_10064445", "reaction_10047033", "reaction_10033889", "reaction_10042897", "reaction_10047053", "reaction_10076806", "reaction_10036023", "reaction_10064581", "reaction_10064503", "reaction_10063573", "reaction_10064534", "reaction_10063450", "reaction_10077001", "reaction_10064531", "reaction_10064526", "reaction_10075576", "reaction_10064511", "reaction_10044151", "reaction_10051261", "reaction_10075631", "reaction_10082889", "reaction_10063454", "reaction_10063456", "reaction_10063448" ] }, "R-BTA-389599": { "id": "pathway_10093588", "reactome": "R-BTA-389599", "name": "Alpha-oxidation of phytanate", "reactions": [ "reaction_10047001", "reaction_10046992", "reaction_10082889", "reaction_10046984", "reaction_10046989" ] }, "R-BTA-352230": { "id": "pathway_10093482", "reactome": "R-BTA-352230", "name": "Amino acid transport across the plasma membrane", "reactions": [ "reaction_10045473", "reaction_10045480", "reaction_10044964", "reaction_10045494", "reaction_10085384", "reaction_10044934", "reaction_10088905", "reaction_10044941", "reaction_10044985", "reaction_10045487", "reaction_10045501", "reaction_10044971", "reaction_10044962", "reaction_10044948", "reaction_10044978", "reaction_10044955" ] }, "R-BTA-187042": { "id": "pathway_10093012", "reactome": "R-BTA-187042", "name": "TRKA activation by NGF", "reactions": [ "reaction_10039270", "reaction_10039272", "reaction_10040684" ] }, "R-BTA-381426": { "id": "pathway_10093550", "reactome": "R-BTA-381426", "name": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)", "reactions": [ "reaction_10088473", "reaction_10046621" ] }, "R-BTA-2559584": { "id": "pathway_10094386", "reactome": "R-BTA-2559584", "name": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)", "reactions": [ "reaction_10068959" ] }, "R-BTA-9663891": { "id": "pathway_10094422", "reactome": "R-BTA-9663891", "name": "Selective autophagy", "reactions": [ "reaction_10070261", "reaction_10087615", "reaction_10088891", "reaction_10070265", "reaction_10070259", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-1227986": { "id": "pathway_10094014", "reactome": "R-BTA-1227986", "name": "Signaling by ERBB2", "reactions": [ "reaction_10057740", "reaction_10061480", "reaction_10057139", "reaction_10077601", "reaction_10084849", "reaction_10077605", "reaction_10057735", "reaction_10057700", "reaction_10057695", "reaction_10057742", "reaction_10086415", "reaction_10057744", "reaction_10057712", "reaction_10083477", "reaction_10057719", "reaction_10061469", "reaction_10061458", "reaction_10083483", "reaction_10061492", "reaction_10057692" ] }, "R-BTA-196843": { "id": "pathway_10093288", "reactome": "R-BTA-196843", "name": "Vitamin B2 (riboflavin) metabolism", "reactions": [ "reaction_10041790", "reaction_10041772", "reaction_10041781", "reaction_10066602", "reaction_10041799" ] }, "R-BTA-449147": { "id": "pathway_10093066", "reactome": "R-BTA-449147", "name": "Signaling by Interleukins", "reactions": [ "reaction_10051194", "reaction_10056201", "reaction_10051936", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10052254", "reaction_10089466", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10089691", "reaction_10050231", "reaction_10042826", "reaction_10051966", "reaction_10050011", "reaction_10089329", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10049970", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10056110", "reaction_10089431", "reaction_10089540", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10090031", "reaction_10089536", "reaction_10089251", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10090027", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10050256", "reaction_10056194", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10089689", "reaction_10043867", "reaction_10077723", "reaction_10056132", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10077424", "reaction_10056207", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10089542", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10087766", "reaction_10049928", "reaction_10050428", "reaction_10083522", "reaction_10039508", "reaction_10050420", "reaction_10087650", "reaction_10052327", "reaction_10089736", "reaction_10051949", "reaction_10089269", "reaction_10089597", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10056168", "reaction_10087793", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10085017", "reaction_10051954", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-157118": { "id": "pathway_10094186", "reactome": "R-BTA-157118", "name": "Signaling by NOTCH", "reactions": [ "reaction_10090409", "reaction_10090834", "reaction_10061449" ] }, "R-BTA-389661": { "id": "pathway_10093592", "reactome": "R-BTA-389661", "name": "Glyoxylate metabolism and glycine degradation", "reactions": [ "reaction_10078366", "reaction_10076450", "reaction_10078402", "reaction_10076441", "reaction_10076459", "reaction_10078393", "reaction_10047019", "reaction_10078701", "reaction_10077458", "reaction_10052056", "reaction_10047022" ] }, "R-BTA-877300": { "id": "pathway_10093858", "reactome": "R-BTA-877300", "name": "Interferon gamma signaling", "reactions": [ "reaction_10051771", "reaction_10051774", "reaction_10051818", "reaction_10051780", "reaction_10051786", "reaction_10052067", "reaction_10051762", "reaction_10091723", "reaction_10051792", "reaction_10051696", "reaction_10051737", "reaction_10055967", "reaction_10051748" ] }, "R-BTA-388844": { "id": "pathway_10093576", "reactome": "R-BTA-388844", "name": "Receptor-type tyrosine-protein phosphatases", "reactions": [ "reaction_10078674", "reaction_10078682", "reaction_10046868", "reaction_10078566" ] }, "R-BTA-390918": { "id": "pathway_10093590", "reactome": "R-BTA-390918", "name": "Peroxisomal lipid metabolism", "reactions": [ "reaction_10047001", "reaction_10054592", "reaction_10047044", "reaction_10046992", "reaction_10082889", "reaction_10082880", "reaction_10046984", "reaction_10047058", "reaction_10075576", "reaction_10047056", "reaction_10047053", "reaction_10077784", "reaction_10046989", "reaction_10047042", "reaction_10047033", "reaction_10077835" ] }, "R-BTA-380612": { "id": "pathway_10092882", "reactome": "R-BTA-380612", "name": "Metabolism of serotonin", "reactions": [ "reaction_10046552", "reaction_10038000" ] }, "R-BTA-73843": { "id": "pathway_10092588", "reactome": "R-BTA-73843", "name": "5-Phosphoribose 1-diphosphate biosynthesis", "reactions": [ "reaction_10034944", "reaction_10036903" ] }, "R-BTA-2424491": { "id": "pathway_10094290", "reactome": "R-BTA-2424491", "name": "DAP12 signaling", "reactions": [ "reaction_10065517", "reaction_10065491" ] }, "R-BTA-1482839": { "id": "pathway_10094104", "reactome": "R-BTA-1482839", "name": "Acyl chain remodelling of PE", "reactions": [ "reaction_10076792", "reaction_10059002", "reaction_10084526", "reaction_10059004", "reaction_10058885", "reaction_10059853", "reaction_10058899", "reaction_10058980" ] }, "R-BTA-389948": { "id": "pathway_10093580", "reactome": "R-BTA-389948", "name": "PD-1 signaling", "reactions": [ "reaction_10046888", "reaction_10091743" ] }, "R-BTA-2161522": { "id": "pathway_10094236", "reactome": "R-BTA-2161522", "name": "Abacavir transport and metabolism", "reactions": [ "reaction_10064439", "reaction_10064584" ] }, "R-BTA-2428924": { "id": "pathway_10092650", "reactome": "R-BTA-2428924", "name": "IGF1R signaling cascade", "reactions": [ "reaction_10075063", "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-8941856": { "id": "pathway_10094804", "reactome": "R-BTA-8941856", "name": "RUNX3 regulates NOTCH signaling", "reactions": [ "reaction_10086241" ] }, "R-BTA-5654708": { "id": "pathway_10094512", "reactome": "R-BTA-5654708", "name": "Downstream signaling of activated FGFR3", "reactions": [ "reaction_10073014", "reaction_10072946", "reaction_10073147", "reaction_10073021", "reaction_10073011", "reaction_10087376", "reaction_10073234", "reaction_10073019", "reaction_10072944", "reaction_10072913", "reaction_10073152", "reaction_10073159", "reaction_10073156", "reaction_10073145", "reaction_10073140" ] }, "R-BTA-2022928": { "id": "pathway_10093854", "reactome": "R-BTA-2022928", "name": "HS-GAG biosynthesis", "reactions": [ "reaction_10063010", "reaction_10062984", "reaction_10063216", "reaction_10063603", "reaction_10063586", "reaction_10063610", "reaction_10051589", "reaction_10063633" ] }, "R-BTA-8854521": { "id": "pathway_10094758", "reactome": "R-BTA-8854521", "name": "Interaction between PHLDA1 and AURKA", "reactions": [ "reaction_10084090", "reaction_10084096" ] }, "R-BTA-5689901": { "id": "pathway_10094624", "reactome": "R-BTA-5689901", "name": "Metalloprotease DUBs", "reactions": [ "reaction_10076119", "reaction_10076112" ] }, "R-BTA-162582": { "id": "pathway_10092534", "reactome": "R-BTA-162582", "name": "Signal Transduction", "reactions": [ "reaction_10047236", "reaction_10073796", "reaction_10040769", "reaction_10090087", "reaction_10073716", "reaction_10041917", "reaction_10047362", "reaction_10047979", "reaction_10041463", "reaction_10047398", "reaction_10091158", "reaction_10063374", "reaction_10047334", "reaction_10091156", "reaction_10063319", "reaction_10073021", "reaction_10090198", "reaction_10086575", "reaction_10067364", "reaction_10057318", "reaction_10068933", "reaction_10056781", "reaction_10068939", "reaction_10047851", "reaction_10091576", "reaction_10063534", "reaction_10068086", "reaction_10063843", "reaction_10083588", "reaction_10069651", "reaction_10083632", "reaction_10090675", "reaction_10037549", "reaction_10072123", "reaction_10037022", "reaction_10083878", "reaction_10083629", "reaction_10091118", "reaction_10060448", "reaction_10083880", "reaction_10075223", "reaction_10043488", "reaction_10091267", "reaction_10040761", "reaction_10061492", "reaction_10057236", "reaction_10090330", "reaction_10072946", "reaction_10083646", "reaction_10040489", "reaction_10072715", "reaction_10083695", "reaction_10088940", "reaction_10074137", "reaction_10040258", "reaction_10047210", "reaction_10047256", "reaction_10041869", "reaction_10046572", "reaction_10091751", "reaction_10049699", "reaction_10071508", "reaction_10091556", "reaction_10046919", "reaction_10073122", "reaction_10040326", "reaction_10076193", "reaction_10040696", "reaction_10046953", "reaction_10047374", "reaction_10058474", "reaction_10073044", "reaction_10089947", "reaction_10091271", "reaction_10071534", "reaction_10068839", "reaction_10089011", "reaction_10044465", "reaction_10046915", "reaction_10074879", "reaction_10067204", "reaction_10040773", "reaction_10084080", "reaction_10074184", "reaction_10064910", "reaction_10040458", "reaction_10045168", "reaction_10072685", "reaction_10046534", "reaction_10047857", "reaction_10045332", "reaction_10090555", "reaction_10040782", "reaction_10073041", "reaction_10063317", "reaction_10048214", "reaction_10072720", "reaction_10091458", "reaction_10035527", "reaction_10040317", "reaction_10047226", "reaction_10072929", "reaction_10071397", "reaction_10084016", "reaction_10071407", "reaction_10064933", "reaction_10046660", "reaction_10067698", "reaction_10072397", "reaction_10089222", "reaction_10072976", "reaction_10071506", "reaction_10046677", "reaction_10039674", "reaction_10091115", "reaction_10072900", "reaction_10036146", "reaction_10046729", "reaction_10077601", "reaction_10041583", "reaction_10072677", "reaction_10091896", "reaction_10057744", "reaction_10040794", "reaction_10068837", "reaction_10046763", "reaction_10083664", "reaction_10063568", "reaction_10071678", "reaction_10073246", "reaction_10090964", "reaction_10073177", "reaction_10075097", "reaction_10063550", "reaction_10063556", "reaction_10048632", "reaction_10089952", "reaction_10057323", "reaction_10039160", "reaction_10074176", "reaction_10069459", "reaction_10049645", "reaction_10073549", "reaction_10047866", "reaction_10068073", "reaction_10039653", "reaction_10073090", "reaction_10047468", "reaction_10090501", "reaction_10069645", "reaction_10053333", "reaction_10063554", "reaction_10057850", "reaction_10090009", "reaction_10075262", "reaction_10091916", "reaction_10090666", "reaction_10036570", "reaction_10089203", "reaction_10069535", "reaction_10092203", "reaction_10072515", "reaction_10049657", "reaction_10073503", "reaction_10066994", "reaction_10048180", "reaction_10087367", "reaction_10040684", "reaction_10046735", "reaction_10072606", "reaction_10073755", "reaction_10074088", "reaction_10041604", "reaction_10091689", "reaction_10075260", "reaction_10088493", "reaction_10072628", "reaction_10071648", "reaction_10073930", "reaction_10092364", "reaction_10090203", "reaction_10074156", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10091864", "reaction_10073182", "reaction_10073921", "reaction_10039651", "reaction_10073559", "reaction_10040860", "reaction_10036616", "reaction_10057302", "reaction_10040286", "reaction_10040393", "reaction_10071504", "reaction_10045384", "reaction_10037045", "reaction_10091812", "reaction_10057139", "reaction_10073904", "reaction_10039736", "reaction_10071356", "reaction_10073234", "reaction_10092205", "reaction_10044470", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10074231", "reaction_10045268", "reaction_10090949", "reaction_10067350", "reaction_10083638", "reaction_10063353", "reaction_10073525", "reaction_10069593", "reaction_10069299", "reaction_10073102", "reaction_10045350", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10073569", "reaction_10044211", "reaction_10067200", "reaction_10039485", "reaction_10072937", "reaction_10074038", "reaction_10091527", "reaction_10073201", "reaction_10047354", "reaction_10045324", "reaction_10040331", "reaction_10088942", "reaction_10039272", "reaction_10067124", "reaction_10091180", "reaction_10090306", "reaction_10072939", "reaction_10040289", "reaction_10056354", "reaction_10073106", "reaction_10083697", "reaction_10073113", "reaction_10048208", "reaction_10045072", "reaction_10039601", "reaction_10043778", "reaction_10091506", "reaction_10035536", "reaction_10064919", "reaction_10073932", "reaction_10047364", "reaction_10069607", "reaction_10049279", "reaction_10057262", "reaction_10090956", "reaction_10072433", "reaction_10039127", "reaction_10073133", "reaction_10057700", "reaction_10083656", "reaction_10073228", "reaction_10092382", "reaction_10057704", "reaction_10047212", "reaction_10049506", "reaction_10041950", "reaction_10040369", "reaction_10057857", "reaction_10041453", "reaction_10071673", "reaction_10091151", "reaction_10069882", "reaction_10049683", "reaction_10089860", "reaction_10073222", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10090452", "reaction_10042976", "reaction_10051656", "reaction_10049894", "reaction_10090103", "reaction_10046588", "reaction_10091921", "reaction_10067694", "reaction_10070628", "reaction_10045292", "reaction_10091902", "reaction_10092002", "reaction_10073853", "reaction_10047366", "reaction_10091832", "reaction_10046666", "reaction_10073004", "reaction_10057177", "reaction_10090311", "reaction_10043744", "reaction_10077605", "reaction_10083652", "reaction_10076840", "reaction_10063544", "reaction_10083933", "reaction_10036607", "reaction_10047234", "reaction_10073731", "reaction_10037004", "reaction_10049520", "reaction_10039592", "reaction_10057719", "reaction_10073940", "reaction_10049478", "reaction_10051667", "reaction_10065099", "reaction_10048660", "reaction_10040310", "reaction_10041863", "reaction_10073851", "reaction_10039180", "reaction_10071556", "reaction_10090563", "reaction_10073129", "reaction_10090145", "reaction_10046917", "reaction_10043315", "reaction_10073083", "reaction_10040299", "reaction_10067879", "reaction_10040785", "reaction_10091275", "reaction_10040570", "reaction_10063382", "reaction_10048178", "reaction_10057284", "reaction_10071320", "reaction_10084723", "reaction_10090559", "reaction_10083935", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10047483", "reaction_10075916", "reaction_10047956", "reaction_10040704", "reaction_10057742", "reaction_10089214", "reaction_10067358", "reaction_10090369", "reaction_10036981", "reaction_10041647", "reaction_10074050", "reaction_10073942", "reaction_10089890", "reaction_10091570", "reaction_10070657", "reaction_10048282", "reaction_10090266", "reaction_10067696", "reaction_10057272", "reaction_10041606", "reaction_10040791", "reaction_10047222", "reaction_10092020", "reaction_10091247", "reaction_10045106", "reaction_10087531", "reaction_10074195", "reaction_10067128", "reaction_10037037", "reaction_10090994", "reaction_10073147", "reaction_10057327", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10090119", "reaction_10067360", "reaction_10039676", "reaction_10075239", "reaction_10041637", "reaction_10040229", "reaction_10040744", "reaction_10045180", "reaction_10040779", "reaction_10090082", "reaction_10090339", "reaction_10091741", "reaction_10048326", "reaction_10089224", "reaction_10049570", "reaction_10057862", "reaction_10048587", "reaction_10072902", "reaction_10039581", "reaction_10046149", "reaction_10084849", "reaction_10070676", "reaction_10091884", "reaction_10039697", "reaction_10063338", "reaction_10053335", "reaction_10049585", "reaction_10073115", "reaction_10072999", "reaction_10039059", "reaction_10086415", "reaction_10090246", "reaction_10073001", "reaction_10040447", "reaction_10063346", "reaction_10071668", "reaction_10089841", "reaction_10040421", "reaction_10083565", "reaction_10048370", "reaction_10089149", "reaction_10047214", "reaction_10091572", "reaction_10057184", "reaction_10045280", "reaction_10074221", "reaction_10091169", "reaction_10075253", "reaction_10073326", "reaction_10057191", "reaction_10056356", "reaction_10073507", "reaction_10057286", "reaction_10092026", "reaction_10073208", "reaction_10048248", "reaction_10090089", "reaction_10047396", "reaction_10047498", "reaction_10049617", "reaction_10035726", "reaction_10089972", "reaction_10061449", "reaction_10040432", "reaction_10069876", "reaction_10047853", "reaction_10074238", "reaction_10090349", "reaction_10073557", "reaction_10087597", "reaction_10090409", "reaction_10047378", "reaction_10057735", "reaction_10051907", "reaction_10073011", "reaction_10065227", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10039209", "reaction_10069456", "reaction_10071526", "reaction_10033926", "reaction_10090098", "reaction_10061458", "reaction_10083483", "reaction_10073071", "reaction_10067362", "reaction_10043877", "reaction_10043832", "reaction_10057337", "reaction_10047206", "reaction_10072138", "reaction_10069448", "reaction_10090925", "reaction_10091878", "reaction_10090091", "reaction_10041649", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10074129", "reaction_10057151", "reaction_10046731", "reaction_10057872", "reaction_10083951", "reaction_10036148", "reaction_10092380", "reaction_10047947", "reaction_10041851", "reaction_10039671", "reaction_10090727", "reaction_10068707", "reaction_10037330", "reaction_10090971", "reaction_10048304", "reaction_10071659", "reaction_10069647", "reaction_10040303", "reaction_10075906", "reaction_10073547", "reaction_10073175", "reaction_10092392", "reaction_10084542", "reaction_10072944", "reaction_10040753", "reaction_10038450", "reaction_10092022", "reaction_10072225", "reaction_10072933", "reaction_10090115", "reaction_10090712", "reaction_10071262", "reaction_10041640", "reaction_10071330", "reaction_10060556", "reaction_10045362", "reaction_10057867", "reaction_10068095", "reaction_10092031", "reaction_10073561", "reaction_10091175", "reaction_10073231", "reaction_10071691", "reaction_10073244", "reaction_10076198", "reaction_10058480", "reaction_10073028", "reaction_10073159", "reaction_10072927", "reaction_10073215", "reaction_10049615", "reaction_10073014", "reaction_10091595", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10039667", "reaction_10040323", "reaction_10049643", "reaction_10073127", "reaction_10063342", "reaction_10073087", "reaction_10047332", "reaction_10038918", "reaction_10090567", "reaction_10047862", "reaction_10047552", "reaction_10073842", "reaction_10083676", "reaction_10036959", "reaction_10073242", "reaction_10091479", "reaction_10086565", "reaction_10073166", "reaction_10039658", "reaction_10074146", "reaction_10043753", "reaction_10090960", "reaction_10047870", "reaction_10047868", "reaction_10075256", "reaction_10057264", "reaction_10090077", "reaction_10049681", "reaction_10073152", "reaction_10089197", "reaction_10045016", "reaction_10035507", "reaction_10083558", "reaction_10046583", "reaction_10073140", "reaction_10048170", "reaction_10057712", "reaction_10040460", "reaction_10072931", "reaction_10092370", "reaction_10086662", "reaction_10046773", "reaction_10036590", "reaction_10059152", "reaction_10072913", "reaction_10047238", "reaction_10092055", "reaction_10073047", "reaction_10067895", "reaction_10039711", "reaction_10043129", "reaction_10057188", "reaction_10081580", "reaction_10089937", "reaction_10072979", "reaction_10072220", "reaction_10089211", "reaction_10089207", "reaction_10041333", "reaction_10069896", "reaction_10051217", "reaction_10043311", "reaction_10072993", "reaction_10091580", "reaction_10040451", "reaction_10039200", "reaction_10091994", "reaction_10090125", "reaction_10048174", "reaction_10040462", "reaction_10063380", "reaction_10053213", "reaction_10042860", "reaction_10090968", "reaction_10075063", "reaction_10073077", "reaction_10090428", "reaction_10075205", "reaction_10041629", "reaction_10083707", "reaction_10057329", "reaction_10072154", "reaction_10083726", "reaction_10057252", "reaction_10053082", "reaction_10091548", "reaction_10047860", "reaction_10091534", "reaction_10076743", "reaction_10087373", "reaction_10091037", "reaction_10073577", "reaction_10069872", "reaction_10073031", "reaction_10040277", "reaction_10073872", "reaction_10071524", "reaction_10048172", "reaction_10047394", "reaction_10091260", "reaction_10089985", "reaction_10071541", "reaction_10083690", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043461", "reaction_10075065", "reaction_10090722", "reaction_10073108", "reaction_10084702", "reaction_10089228", "reaction_10069664", "reaction_10073225", "reaction_10076229", "reaction_10048270", "reaction_10049639", "reaction_10039270", "reaction_10057314", "reaction_10058478", "reaction_10070651", "reaction_10089761", "reaction_10091929", "reaction_10070645", "reaction_10047823", "reaction_10083581", "reaction_10083672", "reaction_10091568", "reaction_10057854", "reaction_10048176", "reaction_10057695", "reaction_10039690", "reaction_10072909", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10037964", "reaction_10090954", "reaction_10073844", "reaction_10087370", "reaction_10068923", "reaction_10080870", "reaction_10083477", "reaction_10073328", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10083622", "reaction_10040453", "reaction_10047989", "reaction_10045156", "reaction_10063305", "reaction_10045094", "reaction_10075218", "reaction_10040495", "reaction_10044472", "reaction_10068078", "reaction_10057740", "reaction_10068704", "reaction_10090571", "reaction_10049637", "reaction_10073240", "reaction_10073806", "reaction_10073145", "reaction_10090456", "reaction_10057175", "reaction_10063849", "reaction_10043739", "reaction_10068088", "reaction_10049659", "reaction_10088496", "reaction_10091763", "reaction_10070931", "reaction_10073199", "reaction_10063408", "reaction_10072081", "reaction_10070594", "reaction_10040386", "reaction_10083729", "reaction_10092394", "reaction_10075251", "reaction_10039155", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10072630", "reaction_10073037", "reaction_10084067", "reaction_10073237", "reaction_10089217", "reaction_10040720", "reaction_10083684", "reaction_10041470", "reaction_10073136", "reaction_10067202", "reaction_10067908", "reaction_10039664", "reaction_10057692", "reaction_10057845", "reaction_10091529", "reaction_10089888", "reaction_10045196", "reaction_10067348", "reaction_10061480", "reaction_10091515", "reaction_10046733", "reaction_10083487", "reaction_10090011", "reaction_10091490", "reaction_10072920", "reaction_10070589", "reaction_10037332", "reaction_10078536", "reaction_10089930", "reaction_10041657", "reaction_10092208", "reaction_10069595", "reaction_10070615", "reaction_10057298", "reaction_10084466", "reaction_10073917", "reaction_10047380", "reaction_10090834", "reaction_10063329", "reaction_10073493", "reaction_10074148", "reaction_10072199", "reaction_10057166", "reaction_10073097", "reaction_10092314", "reaction_10047224", "reaction_10073156", "reaction_10072713" ] }, "R-BTA-193144": { "id": "pathway_10093250", "reactome": "R-BTA-193144", "name": "Estrogen biosynthesis", "reactions": [ "reaction_10041277", "reaction_10077113", "reaction_10084679", "reaction_10076281", "reaction_10041299", "reaction_10051676" ] }, "R-BTA-381119": { "id": "pathway_10093548", "reactome": "R-BTA-381119", "name": "Unfolded Protein Response (UPR)", "reactions": [ "reaction_10046602", "reaction_10046604", "reaction_10085865" ] }, "R-BTA-380108": { "id": "pathway_10093498", "reactome": "R-BTA-380108", "name": "Chemokine receptors bind chemokines", "reactions": [ "reaction_10045072", "reaction_10045106", "reaction_10049520", "reaction_10049570", "reaction_10049639", "reaction_10045168", "reaction_10045196", "reaction_10083880", "reaction_10045156", "reaction_10045094", "reaction_10067358", "reaction_10045180", "reaction_10045280", "reaction_10045268" ] }, "R-BTA-2022857": { "id": "pathway_10094138", "reactome": "R-BTA-2022857", "name": "Keratan sulfate degradation", "reactions": [ "reaction_10063510", "reaction_10091293", "reaction_10060293", "reaction_10060285", "reaction_10060295" ] }, "R-BTA-2142816": { "id": "pathway_10094244", "reactome": "R-BTA-2142816", "name": "Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)", "reactions": [ "reaction_10064511", "reaction_10064516", "reaction_10064531" ] }, "R-BTA-140837": { "id": "pathway_10092912", "reactome": "R-BTA-140837", "name": "Intrinsic Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10091671", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10038205", "reaction_10090718", "reaction_10071946", "reaction_10038221", "reaction_10090185", "reaction_10091546", "reaction_10038166", "reaction_10038201", "reaction_10038213" ] }, "R-BTA-73864": { "id": "pathway_10092602", "reactome": "R-BTA-73864", "name": "RNA Polymerase I Transcription", "reactions": [ "reaction_10035301", "reaction_10035254" ] }, "R-BTA-392499": { "id": "pathway_10092572", "reactome": "R-BTA-392499", "name": "Metabolism of proteins", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10034383", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10074707", "reaction_10081490", "reaction_10050169", "reaction_10049811", "reaction_10048461", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10091124", "reaction_10043698", "reaction_10088807", "reaction_10088922", "reaction_10069329", "reaction_10069498", "reaction_10034224", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10046602", "reaction_10048465", "reaction_10082038", "reaction_10074857", "reaction_10083380", "reaction_10087883", "reaction_10034387", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10075023", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10038107", "reaction_10074833", "reaction_10077363", "reaction_10091120", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10075095", "reaction_10077034", "reaction_10048761", "reaction_10091056", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10075125", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10034905", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10049392", "reaction_10034855", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10083808", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10046723", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10048429", "reaction_10076119", "reaction_10048003", "reaction_10056074", "reaction_10076773", "reaction_10045744", "reaction_10077331", "reaction_10082045", "reaction_10077947", "reaction_10049831", "reaction_10038408", "reaction_10074686", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10049385", "reaction_10074863", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10085865", "reaction_10083231", "reaction_10076610", "reaction_10038082", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10075105", "reaction_10049789", "reaction_10046621", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10048380", "reaction_10076586", "reaction_10040933", "reaction_10048407", "reaction_10060894", "reaction_10046604", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10034365", "reaction_10088734", "reaction_10045696", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10075086", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10045736", "reaction_10075084", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10075019", "reaction_10048958", "reaction_10087848", "reaction_10074869", "reaction_10045694" ] }, "R-BTA-5633008": { "id": "pathway_10094670", "reactome": "R-BTA-5633008", "name": "TP53 Regulates Transcription of Cell Death Genes", "reactions": [ "reaction_10080738", "reaction_10081291", "reaction_10081278", "reaction_10081274", "reaction_10081326", "reaction_10081305", "reaction_10081286", "reaction_10081323", "reaction_10080789", "reaction_10080457", "reaction_10081293" ] }, "R-BTA-204005": { "id": "pathway_10093372", "reactome": "R-BTA-204005", "name": "COPII-mediated vesicle transport", "reactions": [ "reaction_10083380", "reaction_10043649", "reaction_10076775", "reaction_10076610", "reaction_10076778", "reaction_10076635", "reaction_10076736", "reaction_10083377", "reaction_10076584", "reaction_10076698" ] }, "R-BTA-1234174": { "id": "pathway_10093986", "reactome": "R-BTA-1234174", "name": "Cellular response to hypoxia", "reactions": [ "reaction_10056688", "reaction_10056719", "reaction_10056754", "reaction_10056757", "reaction_10056759", "reaction_10056761", "reaction_10056702", "reaction_10056679", "reaction_10056737" ] }, "R-BTA-4086398": { "id": "pathway_10094398", "reactome": "R-BTA-4086398", "name": "Ca2+ pathway", "reactions": [ "reaction_10069456", "reaction_10069459", "reaction_10069448" ] }, "R-BTA-9013423": { "id": "pathway_10094904", "reactome": "R-BTA-9013423", "name": "RAC3 GTPase cycle", "reactions": [ "reaction_10092394", "reaction_10090339", "reaction_10090330", "reaction_10092392", "reaction_10090349" ] }, "R-BTA-380095": { "id": "pathway_10093564", "reactome": "R-BTA-380095", "name": "Tachykinin receptors bind tachykinins", "reactions": [ "reaction_10046729" ] }, "R-BTA-6811436": { "id": "pathway_10094744", "reactome": "R-BTA-6811436", "name": "COPI-independent Golgi-to-ER retrograde traffic", "reactions": [ "reaction_10083712" ] }, "R-BTA-350562": { "id": "pathway_10093470", "reactome": "R-BTA-350562", "name": "Regulation of ornithine decarboxylase (ODC)", "reactions": [ "reaction_10044794", "reaction_10044784", "reaction_10044776" ] }, "R-BTA-392517": { "id": "pathway_10093490", "reactome": "R-BTA-392517", "name": "Rap1 signalling", "reactions": [ "reaction_10052471", "reaction_10053213", "reaction_10052466", "reaction_10047536", "reaction_10045016", "reaction_10047519" ] }, "R-BTA-5576893": { "id": "pathway_10094458", "reactome": "R-BTA-5576893", "name": "Phase 2 - plateau phase", "reactions": [ "reaction_10071800" ] }, "R-BTA-428157": { "id": "pathway_10093728", "reactome": "R-BTA-428157", "name": "Sphingolipid metabolism", "reactions": [ "reaction_10060021", "reaction_10049182", "reaction_10048860", "reaction_10049154", "reaction_10060041", "reaction_10076389", "reaction_10071483", "reaction_10082058", "reaction_10049163", "reaction_10048986", "reaction_10048910", "reaction_10060109", "reaction_10049161", "reaction_10049121", "reaction_10059961", "reaction_10091936", "reaction_10048995", "reaction_10049116", "reaction_10059991", "reaction_10060316", "reaction_10048889", "reaction_10049141", "reaction_10060012", "reaction_10049004", "reaction_10059977", "reaction_10049189", "reaction_10059984", "reaction_10059951", "reaction_10091941", "reaction_10060302", "reaction_10076151", "reaction_10048988", "reaction_10059954", "reaction_10076833", "reaction_10059944", "reaction_10084410", "reaction_10048903", "reaction_10049007", "reaction_10048882", "reaction_10049143", "reaction_10048978", "reaction_10048917", "reaction_10059968", "reaction_10048896", "reaction_10071497", "reaction_10060309" ] }, "R-BTA-6803207": { "id": "pathway_10094680", "reactome": "R-BTA-6803207", "name": "TP53 Regulates Transcription of Caspase Activators and Caspases", "reactions": [ "reaction_10081291", "reaction_10081278", "reaction_10081274", "reaction_10081286", "reaction_10081293" ] }, "R-BTA-209905": { "id": "pathway_10093414", "reactome": "R-BTA-209905", "name": "Catecholamine biosynthesis", "reactions": [ "reaction_10043933" ] }, "R-BTA-5662702": { "id": "pathway_10094554", "reactome": "R-BTA-5662702", "name": "Melanin biosynthesis", "reactions": [ "reaction_10073477" ] }, "R-BTA-211935": { "id": "pathway_10092698", "reactome": "R-BTA-211935", "name": "Fatty acids", "reactions": [ "reaction_10044260", "reaction_10035958", "reaction_10044195", "reaction_10044216" ] }, "R-BTA-9013409": { "id": "pathway_10094898", "reactome": "R-BTA-9013409", "name": "RHOJ GTPase cycle", "reactions": [ "reaction_10090198", "reaction_10090203" ] }, "R-BTA-201451": { "id": "pathway_10093334", "reactome": "R-BTA-201451", "name": "Signaling by BMP", "reactions": [ "reaction_10042976", "reaction_10043311", "reaction_10084542" ] }, "R-BTA-512988": { "id": "pathway_10093824", "reactome": "R-BTA-512988", "name": "Interleukin-3, Interleukin-5 and GM-CSF signaling", "reactions": [ "reaction_10051966", "reaction_10052735", "reaction_10051949", "reaction_10051962", "reaction_10052343", "reaction_10050619", "reaction_10050623", "reaction_10051936", "reaction_10052321", "reaction_10052240", "reaction_10051954", "reaction_10052294", "reaction_10052254", "reaction_10052325", "reaction_10052337", "reaction_10052323", "reaction_10052302", "reaction_10052327" ] }, "R-BTA-425561": { "id": "pathway_10093702", "reactome": "R-BTA-425561", "name": "Sodium/Calcium exchangers", "reactions": [ "reaction_10072522", "reaction_10048526", "reaction_10048504", "reaction_10048533" ] }, "R-BTA-6807878": { "id": "pathway_10094692", "reactome": "R-BTA-6807878", "name": "COPI-mediated anterograde transport", "reactions": [ "reaction_10082038", "reaction_10082045", "reaction_10082026" ] }, "R-BTA-200425": { "id": "pathway_10093328", "reactome": "R-BTA-200425", "name": "Carnitine metabolism", "reactions": [ "reaction_10085185", "reaction_10042897", "reaction_10042860" ] }, "R-BTA-975576": { "id": "pathway_10093928", "reactome": "R-BTA-975576", "name": "N-glycan antennae elongation in the medial/trans-Golgi", "reactions": [ "reaction_10056061", "reaction_10076415", "reaction_10054418", "reaction_10077710", "reaction_10054431", "reaction_10056074", "reaction_10077717", "reaction_10054438", "reaction_10054467", "reaction_10054474", "reaction_10076422", "reaction_10054411" ] }, "R-BTA-611105": { "id": "pathway_10092968", "reactome": "R-BTA-611105", "name": "Respiratory electron transport", "reactions": [ "reaction_10080521", "reaction_10080519", "reaction_10080517", "reaction_10038895", "reaction_10080515", "reaction_10038647" ] }, "R-BTA-72737": { "id": "pathway_10092576", "reactome": "R-BTA-72737", "name": "Cap-dependent Translation Initiation", "reactions": [ "reaction_10034855", "reaction_10034365", "reaction_10034383", "reaction_10034387", "reaction_10034905" ] }, "R-BTA-190236": { "id": "pathway_10093176", "reactome": "R-BTA-190236", "name": "Signaling by FGFR", "reactions": [ "reaction_10072979", "reaction_10073147", "reaction_10057327", "reaction_10040769", "reaction_10072993", "reaction_10040744", "reaction_10040779", "reaction_10073077", "reaction_10073234", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10053082", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10072999", "reaction_10087373", "reaction_10073102", "reaction_10073001", "reaction_10073031", "reaction_10072957", "reaction_10073184", "reaction_10073119", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10072946", "reaction_10073326", "reaction_10072939", "reaction_10073108", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10073225", "reaction_10057314", "reaction_10073122", "reaction_10040696", "reaction_10073133", "reaction_10073011", "reaction_10073044", "reaction_10073228", "reaction_10072909", "reaction_10057704", "reaction_10087370", "reaction_10040773", "reaction_10073328", "reaction_10073071", "reaction_10057337", "reaction_10073041", "reaction_10040782", "reaction_10073222", "reaction_10072929", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10072976", "reaction_10073199", "reaction_10073004", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10073237", "reaction_10073246", "reaction_10040720", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10073215", "reaction_10073014", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10073019", "reaction_10072935", "reaction_10072920", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10073242", "reaction_10087367", "reaction_10073166", "reaction_10083935", "reaction_10057707", "reaction_10040704", "reaction_10073152", "reaction_10073140", "reaction_10072931", "reaction_10087376", "reaction_10073097", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10057302" ] }, "R-BTA-8853659": { "id": "pathway_10094762", "reactome": "R-BTA-8853659", "name": "RET signaling", "reactions": [ "reaction_10084326", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10084330", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10084311", "reaction_10084196", "reaction_10084194", "reaction_10084135", "reaction_10084309", "reaction_10084393", "reaction_10084185", "reaction_10084198", "reaction_10084169", "reaction_10084141", "reaction_10084379", "reaction_10084131", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-1855191": { "id": "pathway_10094172", "reactome": "R-BTA-1855191", "name": "Synthesis of IPs in the nucleus", "reactions": [ "reaction_10061128", "reaction_10061049", "reaction_10061137", "reaction_10060951", "reaction_10060993", "reaction_10061131", "reaction_10061017", "reaction_10061052", "reaction_10061119", "reaction_10061031" ] }, "R-BTA-3371497": { "id": "pathway_10094358", "reactome": "R-BTA-3371497", "name": "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "reactions": [ "reaction_10067955", "reaction_10068022" ] }, "R-BTA-2555396": { "id": "pathway_10094300", "reactome": "R-BTA-2555396", "name": "Mitotic Metaphase and Anaphase", "reactions": [ "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10065708", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-209952": { "id": "pathway_10093530", "reactome": "R-BTA-209952", "name": "Peptide hormone biosynthesis", "reactions": [ "reaction_10045696", "reaction_10045736", "reaction_10045744", "reaction_10045694" ] }, "R-BTA-9006925": { "id": "pathway_10092792", "reactome": "R-BTA-9006925", "name": "Intracellular signaling by second messengers", "reactions": [ "reaction_10060556", "reaction_10037022", "reaction_10037004", "reaction_10065227", "reaction_10060448", "reaction_10049478", "reaction_10041863", "reaction_10065099", "reaction_10037024", "reaction_10036981", "reaction_10087531" ] }, "R-BTA-379397": { "id": "pathway_10093542", "reactome": "R-BTA-379397", "name": "Enzymatic degradation of dopamine by COMT", "reactions": [ "reaction_10046153", "reaction_10088657" ] }, "R-BTA-174417": { "id": "pathway_10095018", "reactome": "R-BTA-174417", "name": "Telomere C-strand (Lagging Strand) Synthesis", "reactions": [ "reaction_10091663" ] }, "R-BTA-1296053": { "id": "pathway_10094036", "reactome": "R-BTA-1296053", "name": "Classical Kir channels", "reactions": [ "reaction_10057418" ] }, "R-BTA-196854": { "id": "pathway_10092520", "reactome": "R-BTA-196854", "name": "Metabolism of vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10085855", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10038427", "reaction_10066401", "reaction_10041772", "reaction_10081928", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10090493", "reaction_10041840", "reaction_10066249", "reaction_10041790", "reaction_10069948", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10058514", "reaction_10053350", "reaction_10086748", "reaction_10054395", "reaction_10041753", "reaction_10058524", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10070971", "reaction_10058511", "reaction_10081977", "reaction_10081935", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10054375", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10058785", "reaction_10065445", "reaction_10066247", "reaction_10065437", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10086750", "reaction_10053363", "reaction_10065441", "reaction_10081984", "reaction_10064591", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10085853", "reaction_10046968", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-975155": { "id": "pathway_10093026", "reactome": "R-BTA-975155", "name": "MyD88 dependent cascade initiated on endosome", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-113418": { "id": "pathway_10092812", "reactome": "R-BTA-113418", "name": "Formation of the Early Elongation Complex", "reactions": [ "reaction_10037205", "reaction_10037203" ] }, "R-BTA-8980692": { "id": "pathway_10094862", "reactome": "R-BTA-8980692", "name": "RHOA GTPase cycle", "reactions": [ "reaction_10089890", "reaction_10089860", "reaction_10089930", "reaction_10089888", "reaction_10089149", "reaction_10089011" ] }, "R-BTA-9623433": { "id": "pathway_10094952", "reactome": "R-BTA-9623433", "name": "NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis", "reactions": [ "reaction_10090571", "reaction_10090567", "reaction_10090555" ] }, "R-BTA-9029569": { "id": "pathway_10094922", "reactome": "R-BTA-9029569", "name": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux", "reactions": [ "reaction_10090456", "reaction_10090563", "reaction_10090559", "reaction_10090452" ] }, "R-BTA-8852405": { "id": "pathway_10094678", "reactome": "R-BTA-8852405", "name": "Signaling by MST1", "reactions": [ "reaction_10084080", "reaction_10084067", "reaction_10080870" ] }, "R-BTA-8876198": { "id": "pathway_10094800", "reactome": "R-BTA-8876198", "name": "RAB GEFs exchange GTP for GDP on RABs", "reactions": [ "reaction_10085988", "reaction_10086097", "reaction_10086136", "reaction_10085932", "reaction_10086209", "reaction_10086019", "reaction_10086182", "reaction_10086054" ] }, "R-BTA-425986": { "id": "pathway_10093706", "reactome": "R-BTA-425986", "name": "Sodium/Proton exchangers", "reactions": [ "reaction_10048567", "reaction_10048550" ] }, "R-BTA-1482922": { "id": "pathway_10094098", "reactome": "R-BTA-1482922", "name": "Acyl chain remodelling of PI", "reactions": [ "reaction_10058841", "reaction_10059000", "reaction_10059026", "reaction_10059851", "reaction_10058874", "reaction_10058975" ] }, "R-BTA-212165": { "id": "pathway_10093442", "reactome": "R-BTA-212165", "name": "Epigenetic regulation of gene expression", "reactions": [ "reaction_10070702", "reaction_10070700", "reaction_10044381", "reaction_10044390", "reaction_10071065", "reaction_10044333", "reaction_10048682", "reaction_10048717", "reaction_10048720", "reaction_10044361" ] }, "R-BTA-1566948": { "id": "pathway_10094222", "reactome": "R-BTA-1566948", "name": "Elastic fibre formation", "reactions": [ "reaction_10065336", "reaction_10064435", "reaction_10065435", "reaction_10063839", "reaction_10064437" ] }, "R-BTA-9013408": { "id": "pathway_10094894", "reactome": "R-BTA-9013408", "name": "RHOG GTPase cycle", "reactions": [ "reaction_10090125", "reaction_10090145", "reaction_10090098", "reaction_10090119", "reaction_10090115", "reaction_10090103" ] }, "R-BTA-9706019": { "id": "pathway_10095038", "reactome": "R-BTA-9706019", "name": "RHOBTB3 ATPase cycle", "reactions": [ "reaction_10092203", "reaction_10092208", "reaction_10092205" ] }, "R-BTA-3295583": { "id": "pathway_10094346", "reactome": "R-BTA-3295583", "name": "TRP channels", "reactions": [ "reaction_10092050", "reaction_10067332", "reaction_10067346" ] }, "R-BTA-166187": { "id": "pathway_10093010", "reactome": "R-BTA-166187", "name": "Mitochondrial Uncoupling", "reactions": [ "reaction_10039240", "reaction_10039254", "reaction_10039604", "reaction_10039242" ] }, "R-BTA-3247509": { "id": "pathway_10093976", "reactome": "R-BTA-3247509", "name": "Chromatin modifying enzymes", "reactions": [ "reaction_10072790", "reaction_10069838", "reaction_10070757", "reaction_10073406", "reaction_10073416", "reaction_10069939", "reaction_10070377", "reaction_10069937", "reaction_10070516", "reaction_10072725", "reaction_10073382", "reaction_10067596", "reaction_10072655", "reaction_10070392", "reaction_10070896", "reaction_10069796", "reaction_10056383", "reaction_10073384", "reaction_10070409", "reaction_10072755", "reaction_10068569", "reaction_10073396", "reaction_10072788", "reaction_10073380", "reaction_10069719", "reaction_10069754", "reaction_10071886", "reaction_10069769", "reaction_10069747", "reaction_10073394", "reaction_10068725", "reaction_10072752", "reaction_10073404", "reaction_10066651", "reaction_10069740", "reaction_10072750", "reaction_10072778", "reaction_10066966", "reaction_10070520", "reaction_10070962", "reaction_10073402", "reaction_10069846", "reaction_10070282", "reaction_10073400", "reaction_10068699", "reaction_10072823", "reaction_10085017", "reaction_10072813", "reaction_10091745", "reaction_10068844" ] }, "R-BTA-1280215": { "id": "pathway_10093068", "reactome": "R-BTA-1280215", "name": "Cytokine Signaling in Immune system", "reactions": [ "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10051936", "reaction_10052213", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10056268", "reaction_10051762", "reaction_10052254", "reaction_10089466", "reaction_10074266", "reaction_10054791", "reaction_10051696", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10092165", "reaction_10089691", "reaction_10050231", "reaction_10070719", "reaction_10042826", "reaction_10077790", "reaction_10051966", "reaction_10052196", "reaction_10073690", "reaction_10050011", "reaction_10089329", "reaction_10092257", "reaction_10090919", "reaction_10051786", "reaction_10090844", "reaction_10092043", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10074280", "reaction_10043488", "reaction_10074314", "reaction_10052337", "reaction_10077874", "reaction_10051774", "reaction_10092108", "reaction_10049970", "reaction_10052217", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10089341", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10092139", "reaction_10055958", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10092126", "reaction_10056110", "reaction_10071975", "reaction_10051737", "reaction_10074340", "reaction_10071982", "reaction_10089431", "reaction_10089540", "reaction_10073757", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10052067", "reaction_10090031", "reaction_10089536", "reaction_10056287", "reaction_10052210", "reaction_10089251", "reaction_10057834", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10054779", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10092173", "reaction_10091723", "reaction_10090027", "reaction_10074312", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10051818", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10055955", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10057823", "reaction_10074318", "reaction_10056289", "reaction_10050256", "reaction_10056194", "reaction_10055946", "reaction_10055967", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10090916", "reaction_10089689", "reaction_10092195", "reaction_10074320", "reaction_10052236", "reaction_10043867", "reaction_10077723", "reaction_10089349", "reaction_10060694", "reaction_10052147", "reaction_10051780", "reaction_10056132", "reaction_10084305", "reaction_10051748", "reaction_10073765", "reaction_10051771", "reaction_10092183", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10092151", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10091725", "reaction_10056207", "reaction_10092147", "reaction_10052229", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10076165", "reaction_10056315", "reaction_10089542", "reaction_10092033", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10089703", "reaction_10087766", "reaction_10060730", "reaction_10056335", "reaction_10049928", "reaction_10073708", "reaction_10050428", "reaction_10083522", "reaction_10071948", "reaction_10051792", "reaction_10060412", "reaction_10089696", "reaction_10039508", "reaction_10052159", "reaction_10050420", "reaction_10072030", "reaction_10087650", "reaction_10056283", "reaction_10052327", "reaction_10052233", "reaction_10089736", "reaction_10092143", "reaction_10051949", "reaction_10089269", "reaction_10076237", "reaction_10092159", "reaction_10052189", "reaction_10074308", "reaction_10089597", "reaction_10056297", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074306", "reaction_10074310", "reaction_10092141", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10054524", "reaction_10092137", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10092040", "reaction_10085017", "reaction_10051954", "reaction_10057836", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-1299503": { "id": "pathway_10094042", "reactome": "R-BTA-1299503", "name": "TWIK related potassium channel (TREK)", "reactions": [ "reaction_10057588" ] }, "R-BTA-877312": { "id": "pathway_10093862", "reactome": "R-BTA-877312", "name": "Regulation of IFNG signaling", "reactions": [ "reaction_10051818", "reaction_10055967", "reaction_10051792" ] }, "R-BTA-5668599": { "id": "pathway_10094558", "reactome": "R-BTA-5668599", "name": "RHO GTPases Activate NADPH Oxidases", "reactions": [ "reaction_10091169", "reaction_10073731", "reaction_10091180", "reaction_10073755", "reaction_10091175", "reaction_10073716" ] }, "R-BTA-450294": { "id": "pathway_10093060", "reactome": "R-BTA-450294", "name": "MAP kinase activation", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-171007": { "id": "pathway_10093104", "reactome": "R-BTA-171007", "name": "p38MAPK events", "reactions": [ "reaction_10039736", "reaction_10040570" ] }, "R-BTA-73728": { "id": "pathway_10092598", "reactome": "R-BTA-73728", "name": "RNA Polymerase I Promoter Opening", "reactions": [ "reaction_10035254" ] }, "R-BTA-5620971": { "id": "pathway_10092824", "reactome": "R-BTA-5620971", "name": "Pyroptosis", "reactions": [ "reaction_10092350", "reaction_10092354", "reaction_10091425", "reaction_10037253", "reaction_10091429", "reaction_10091439", "reaction_10092358", "reaction_10092356", "reaction_10091415", "reaction_10081905", "reaction_10092352", "reaction_10091423", "reaction_10092341", "reaction_10091409" ] }, "R-BTA-77289": { "id": "pathway_10092524", "reactome": "R-BTA-77289", "name": "Mitochondrial Fatty Acid Beta-Oxidation", "reactions": [ "reaction_10033889", "reaction_10076806", "reaction_10036220", "reaction_10036023", "reaction_10036021", "reaction_10036025", "reaction_10033912", "reaction_10033896", "reaction_10036038", "reaction_10075607", "reaction_10036029", "reaction_10036042", "reaction_10036040", "reaction_10036664", "reaction_10075631", "reaction_10086403", "reaction_10036027", "reaction_10036218", "reaction_10036012" ] }, "R-BTA-1168372": { "id": "pathway_10093966", "reactome": "R-BTA-1168372", "name": "Downstream signaling events of B Cell Receptor (BCR)", "reactions": [ "reaction_10091817", "reaction_10056239" ] }, "R-BTA-3214858": { "id": "pathway_10094428", "reactome": "R-BTA-3214858", "name": "RMTs methylate histone arginines", "reactions": [ "reaction_10070520", "reaction_10070392", "reaction_10070757", "reaction_10070896", "reaction_10073416", "reaction_10070282", "reaction_10070409", "reaction_10070377", "reaction_10070516" ] }, "R-BTA-389542": { "id": "pathway_10093584", "reactome": "R-BTA-389542", "name": "NADPH regeneration", "reactions": [ "reaction_10046968" ] }, "R-BTA-197264": { "id": "pathway_10093290", "reactome": "R-BTA-197264", "name": "Nicotinamide salvaging", "reactions": [ "reaction_10041808", "reaction_10082143", "reaction_10065210", "reaction_10081984", "reaction_10071643", "reaction_10081977", "reaction_10088867", "reaction_10049170", "reaction_10041824", "reaction_10086623" ] }, "R-BTA-3214847": { "id": "pathway_10094348", "reactome": "R-BTA-3214847", "name": "HATs acetylate histones", "reactions": [ "reaction_10071886", "reaction_10067596", "reaction_10068569" ] }, "R-BTA-416476": { "id": "pathway_10092846", "reactome": "R-BTA-416476", "name": "G alpha (q) signalling events", "reactions": [ "reaction_10047979", "reaction_10089224", "reaction_10037549", "reaction_10089222", "reaction_10064915", "reaction_10064910", "reaction_10041950", "reaction_10048580", "reaction_10076743", "reaction_10064919", "reaction_10048543", "reaction_10048632", "reaction_10048587", "reaction_10089203", "reaction_10048660", "reaction_10047823", "reaction_10046149" ] }, "R-BTA-352238": { "id": "pathway_10093462", "reactome": "R-BTA-352238", "name": "Breakdown of the nuclear lamina", "reactions": [ "reaction_10044578", "reaction_10044568", "reaction_10090575" ] }, "R-BTA-73856": { "id": "pathway_10092722", "reactome": "R-BTA-73856", "name": "RNA Polymerase II Transcription Termination", "reactions": [ "reaction_10036915", "reaction_10036080" ] }, "R-BTA-1280218": { "id": "pathway_10093314", "reactome": "R-BTA-1280218", "name": "Adaptive Immune System", "reactions": [ "reaction_10075009", "reaction_10065009", "reaction_10043302", "reaction_10055821", "reaction_10053213", "reaction_10065051", "reaction_10046932", "reaction_10046807", "reaction_10043300", "reaction_10055448", "reaction_10046888", "reaction_10083967", "reaction_10046909", "reaction_10042129", "reaction_10043262", "reaction_10043212", "reaction_10042253", "reaction_10056805", "reaction_10064219", "reaction_10043659", "reaction_10055783", "reaction_10055491", "reaction_10065055", "reaction_10087823", "reaction_10043274", "reaction_10057004", "reaction_10063972", "reaction_10047530", "reaction_10084658", "reaction_10056910", "reaction_10043219", "reaction_10065227", "reaction_10042623", "reaction_10075923", "reaction_10083959", "reaction_10046787", "reaction_10043182", "reaction_10055453", "reaction_10055444", "reaction_10074901", "reaction_10046903", "reaction_10065011", "reaction_10043298", "reaction_10043304", "reaction_10064068", "reaction_10084867", "reaction_10043270", "reaction_10056912", "reaction_10046959", "reaction_10064214", "reaction_10091743", "reaction_10055451", "reaction_10043244", "reaction_10064221", "reaction_10056982", "reaction_10056914", "reaction_10074993", "reaction_10056903", "reaction_10074899", "reaction_10055431", "reaction_10065019", "reaction_10076963", "reaction_10065021", "reaction_10055817", "reaction_10043193", "reaction_10043252", "reaction_10087807", "reaction_10055460", "reaction_10046907", "reaction_10046943", "reaction_10056835", "reaction_10047519", "reaction_10054866", "reaction_10091817", "reaction_10046811", "reaction_10052471", "reaction_10084672", "reaction_10046822", "reaction_10043225", "reaction_10042786", "reaction_10052466", "reaction_10084401", "reaction_10045016", "reaction_10043241", "reaction_10042635", "reaction_10046834", "reaction_10064118", "reaction_10047536", "reaction_10046951", "reaction_10064277", "reaction_10084865", "reaction_10055819", "reaction_10056239" ] }, "R-BTA-190241": { "id": "pathway_10093182", "reactome": "R-BTA-190241", "name": "FGFR2 ligand binding and activation", "reactions": [ "reaction_10040785", "reaction_10040720", "reaction_10073328", "reaction_10040788", "reaction_10040744" ] }, "R-BTA-1461957": { "id": "pathway_10094082", "reactome": "R-BTA-1461957", "name": "Beta defensins", "reactions": [ "reaction_10058492", "reaction_10058486", "reaction_10058456", "reaction_10061657" ] }, "R-BTA-2024096": { "id": "pathway_10094160", "reactome": "R-BTA-2024096", "name": "HS-GAG degradation", "reactions": [ "reaction_10063801", "reaction_10060625", "reaction_10063803", "reaction_10060671", "reaction_10063805", "reaction_10063022", "reaction_10060685", "reaction_10060678", "reaction_10060741", "reaction_10060634" ] }, "R-BTA-71387": { "id": "pathway_10092456", "reactome": "R-BTA-71387", "name": "Metabolism of carbohydrates", "reactions": [ "reaction_10039887", "reaction_10077793", "reaction_10033592", "reaction_10062697", "reaction_10036903", "reaction_10073438", "reaction_10034118", "reaction_10090645", "reaction_10063216", "reaction_10088737", "reaction_10064393", "reaction_10063807", "reaction_10051589", "reaction_10060634", "reaction_10063485", "reaction_10062701", "reaction_10091289", "reaction_10034013", "reaction_10063508", "reaction_10061251", "reaction_10064353", "reaction_10064597", "reaction_10033561", "reaction_10060829", "reaction_10034157", "reaction_10033638", "reaction_10063022", "reaction_10041878", "reaction_10061395", "reaction_10033620", "reaction_10063249", "reaction_10063510", "reaction_10063610", "reaction_10061651", "reaction_10080765", "reaction_10060741", "reaction_10060827", "reaction_10061612", "reaction_10090854", "reaction_10060295", "reaction_10045692", "reaction_10063010", "reaction_10078710", "reaction_10064355", "reaction_10090851", "reaction_10042801", "reaction_10090772", "reaction_10080747", "reaction_10060031", "reaction_10034071", "reaction_10067610", "reaction_10076815", "reaction_10067254", "reaction_10045043", "reaction_10089230", "reaction_10080756", "reaction_10050637", "reaction_10063633", "reaction_10090620", "reaction_10067240", "reaction_10034041", "reaction_10045029", "reaction_10063603", "reaction_10090696", "reaction_10045050", "reaction_10090638", "reaction_10034944", "reaction_10063532", "reaction_10090856", "reaction_10091286", "reaction_10033718", "reaction_10041885", "reaction_10068748", "reaction_10064595", "reaction_10063520", "reaction_10067247", "reaction_10061642", "reaction_10090703", "reaction_10088744", "reaction_10060685", "reaction_10067639", "reaction_10063801", "reaction_10091291", "reaction_10033611", "reaction_10090799", "reaction_10033629", "reaction_10063803", "reaction_10067634", "reaction_10039890", "reaction_10091293", "reaction_10048727", "reaction_10060678", "reaction_10072894", "reaction_10060825", "reaction_10060625", "reaction_10033570", "reaction_10090611", "reaction_10063232", "reaction_10063805", "reaction_10061402", "reaction_10063014", "reaction_10062508", "reaction_10034043", "reaction_10062463", "reaction_10034238", "reaction_10062674", "reaction_10090867", "reaction_10034032", "reaction_10062984", "reaction_10033579", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10072825", "reaction_10061350", "reaction_10060293", "reaction_10090802", "reaction_10060671", "reaction_10062655", "reaction_10064593", "reaction_10090822", "reaction_10033594", "reaction_10063477", "reaction_10090819", "reaction_10060842", "reaction_10088898", "reaction_10084129", "reaction_10073431", "reaction_10067648", "reaction_10060285", "reaction_10067622", "reaction_10068755", "reaction_10063530", "reaction_10090631", "reaction_10090774", "reaction_10051570", "reaction_10067644", "reaction_10063586", "reaction_10034138", "reaction_10090797", "reaction_10034140", "reaction_10083115", "reaction_10064391" ] }, "R-BTA-8984722": { "id": "pathway_10094840", "reactome": "R-BTA-8984722", "name": "Interleukin-35 Signalling", "reactions": [ "reaction_10089321", "reaction_10087763", "reaction_10089329", "reaction_10089331", "reaction_10089333", "reaction_10087780" ] }, "R-BTA-8963693": { "id": "pathway_10092490", "reactome": "R-BTA-8963693", "name": "Aspartate and asparagine metabolism", "reactions": [ "reaction_10033716", "reaction_10076130", "reaction_10045029", "reaction_10033728", "reaction_10076406", "reaction_10033718", "reaction_10033737", "reaction_10078529" ] }, "R-BTA-112412": { "id": "pathway_10092638", "reactome": "R-BTA-112412", "name": "SOS-mediated signalling", "reactions": [ "reaction_10035507" ] }, "R-BTA-209931": { "id": "pathway_10093408", "reactome": "R-BTA-209931", "name": "Serotonin and melatonin biosynthesis", "reactions": [ "reaction_10043948", "reaction_10043917" ] }, "R-BTA-2022377": { "id": "pathway_10094988", "reactome": "R-BTA-2022377", "name": "Metabolism of Angiotensinogen to Angiotensins", "reactions": [ "reaction_10091056" ] }, "R-BTA-8964540": { "id": "pathway_10092484", "reactome": "R-BTA-8964540", "name": "Alanine metabolism", "reactions": [ "reaction_10033681" ] }, "R-BTA-156827": { "id": "pathway_10092906", "reactome": "R-BTA-156827", "name": "L13a-mediated translational silencing of Ceruloplasmin expression", "reactions": [ "reaction_10038082" ] }, "R-BTA-5675482": { "id": "pathway_10094366", "reactome": "R-BTA-5675482", "name": "Regulation of necroptotic cell death", "reactions": [ "reaction_10091779", "reaction_10091773", "reaction_10074254", "reaction_10091793", "reaction_10071534", "reaction_10091808", "reaction_10074240", "reaction_10091806", "reaction_10068030", "reaction_10091810", "reaction_10091783" ] }, "R-BTA-112315": { "id": "pathway_10092498", "reactome": "R-BTA-112315", "name": "Transmission across Chemical Synapses", "reactions": [ "reaction_10046552", "reaction_10051085", "reaction_10039653", "reaction_10033746", "reaction_10081481", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10049090", "reaction_10051989", "reaction_10049583", "reaction_10033755", "reaction_10052013", "reaction_10052018", "reaction_10050517", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10071437", "reaction_10046151", "reaction_10054318", "reaction_10051999", "reaction_10038000", "reaction_10045419", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10054372", "reaction_10045423", "reaction_10088657", "reaction_10036981", "reaction_10051498", "reaction_10044076", "reaction_10044540", "reaction_10090547", "reaction_10044086", "reaction_10051525", "reaction_10049478", "reaction_10051523", "reaction_10046153", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10039664" ] }, "R-BTA-168249": { "id": "pathway_10093004", "reactome": "R-BTA-168249", "name": "Innate Immune System", "reactions": [ "reaction_10063376", "reaction_10050196", "reaction_10066551", "reaction_10078759", "reaction_10066144", "reaction_10066102", "reaction_10056531", "reaction_10053134", "reaction_10072364", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10066536", "reaction_10080844", "reaction_10063374", "reaction_10067223", "reaction_10077921", "reaction_10066094", "reaction_10072388", "reaction_10066141", "reaction_10050231", "reaction_10056088", "reaction_10042826", "reaction_10065402", "reaction_10081265", "reaction_10072045", "reaction_10065413", "reaction_10063353", "reaction_10090400", "reaction_10081510", "reaction_10039217", "reaction_10061502", "reaction_10051836", "reaction_10083100", "reaction_10080435", "reaction_10065407", "reaction_10081397", "reaction_10067233", "reaction_10080842", "reaction_10053048", "reaction_10072057", "reaction_10056416", "reaction_10043488", "reaction_10086405", "reaction_10072011", "reaction_10082012", "reaction_10056084", "reaction_10083106", "reaction_10040197", "reaction_10081385", "reaction_10085369", "reaction_10082967", "reaction_10039465", "reaction_10060783", "reaction_10053058", "reaction_10079949", "reaction_10079199", "reaction_10054678", "reaction_10071975", "reaction_10071982", "reaction_10061657", "reaction_10050218", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10043182", "reaction_10080063", "reaction_10050254", "reaction_10065517", "reaction_10066082", "reaction_10077924", "reaction_10041950", "reaction_10070906", "reaction_10072383", "reaction_10066127", "reaction_10060785", "reaction_10039778", "reaction_10072374", "reaction_10072002", "reaction_10066180", "reaction_10065894", "reaction_10084706", "reaction_10066151", "reaction_10050192", "reaction_10066059", "reaction_10058492", "reaction_10066238", "reaction_10081559", "reaction_10081404", "reaction_10067229", "reaction_10072061", "reaction_10081406", "reaction_10081410", "reaction_10066080", "reaction_10084683", "reaction_10058486", "reaction_10078929", "reaction_10066052", "reaction_10081943", "reaction_10079653", "reaction_10066147", "reaction_10050256", "reaction_10067225", "reaction_10066120", "reaction_10080831", "reaction_10084636", "reaction_10061174", "reaction_10054649", "reaction_10055971", "reaction_10066172", "reaction_10065642", "reaction_10079391", "reaction_10060773", "reaction_10080719", "reaction_10081905", "reaction_10056539", "reaction_10082977", "reaction_10053122", "reaction_10081432", "reaction_10072053", "reaction_10082004", "reaction_10084020", "reaction_10090019", "reaction_10092318", "reaction_10077926", "reaction_10065491", "reaction_10072006", "reaction_10058388", "reaction_10041863", "reaction_10082008", "reaction_10066559", "reaction_10066880", "reaction_10039782", "reaction_10039481", "reaction_10050208", "reaction_10054736", "reaction_10053095", "reaction_10071948", "reaction_10047907", "reaction_10082183", "reaction_10056082", "reaction_10067231", "reaction_10060759", "reaction_10039508", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10077919", "reaction_10063368", "reaction_10065388", "reaction_10056090", "reaction_10084322", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10058456", "reaction_10066168", "reaction_10066608", "reaction_10066532", "reaction_10053046", "reaction_10087797", "reaction_10081506", "reaction_10072392", "reaction_10081085", "reaction_10077904", "reaction_10072395" ] }, "R-BTA-446107": { "id": "pathway_10093748", "reactome": "R-BTA-446107", "name": "Type I hemidesmosome assembly", "reactions": [ "reaction_10049304" ] }, "R-BTA-5610780": { "id": "pathway_10094480", "reactome": "R-BTA-5610780", "name": "Degradation of GLI1 by the proteasome", "reactions": [ "reaction_10072138" ] }, "R-BTA-5693568": { "id": "pathway_10094598", "reactome": "R-BTA-5693568", "name": "Resolution of D-loop Structures through Holliday Junction Intermediates", "reactions": [ "reaction_10075165", "reaction_10075151" ] }, "R-BTA-190872": { "id": "pathway_10093204", "reactome": "R-BTA-190872", "name": "Transport of connexons to the plasma membrane", "reactions": [ "reaction_10040857", "reaction_10040842", "reaction_10050458" ] }, "R-BTA-110329": { "id": "pathway_10092748", "reactome": "R-BTA-110329", "name": "Cleavage of the damaged pyrimidine ", "reactions": [ "reaction_10036716", "reaction_10036767", "reaction_10036709", "reaction_10036729", "reaction_10036736", "reaction_10036743" ] }, "R-BTA-8878166": { "id": "pathway_10094826", "reactome": "R-BTA-8878166", "name": "Transcriptional regulation by RUNX2", "reactions": [ "reaction_10089679", "reaction_10089681", "reaction_10089357", "reaction_10086716", "reaction_10089640", "reaction_10089610", "reaction_10086724" ] }, "R-BTA-70263": { "id": "pathway_10092476", "reactome": "R-BTA-70263", "name": "Gluconeogenesis", "reactions": [ "reaction_10045692", "reaction_10067240", "reaction_10067247", "reaction_10033757", "reaction_10067254", "reaction_10033638", "reaction_10045029", "reaction_10045043", "reaction_10045050", "reaction_10034238", "reaction_10033718", "reaction_10041878", "reaction_10041885" ] }, "R-BTA-5693579": { "id": "pathway_10094590", "reactome": "R-BTA-5693579", "name": "Homologous DNA Pairing and Strand Exchange", "reactions": [ "reaction_10074877" ] }, "R-BTA-68875": { "id": "pathway_10094258", "reactome": "R-BTA-68875", "name": "Mitotic Prophase", "reactions": [ "reaction_10070705", "reaction_10065572", "reaction_10065095", "reaction_10064733", "reaction_10066345", "reaction_10065563", "reaction_10065177", "reaction_10064904", "reaction_10065201", "reaction_10069491", "reaction_10066324" ] }, "R-BTA-177135": { "id": "pathway_10092932", "reactome": "R-BTA-177135", "name": "Conjugation of benzoate with glycine", "reactions": [ "reaction_10038371", "reaction_10038354" ] }, "R-BTA-111452": { "id": "pathway_10092816", "reactome": "R-BTA-111452", "name": "Activation and oligomerization of BAK protein", "reactions": [ "reaction_10037622", "reaction_10037237", "reaction_10039520" ] }, "R-BTA-373080": { "id": "pathway_10092984", "reactome": "R-BTA-373080", "name": "Class B/2 (Secretin family receptors)", "reactions": [ "reaction_10048304", "reaction_10048248", "reaction_10048326", "reaction_10051907", "reaction_10048270", "reaction_10048282", "reaction_10086575", "reaction_10038918", "reaction_10049681", "reaction_10086565" ] }, "R-BTA-1963640": { "id": "pathway_10094062", "reactome": "R-BTA-1963640", "name": "GRB2 events in ERBB2 signaling", "reactions": [ "reaction_10057695", "reaction_10057692" ] }, "R-BTA-434316": { "id": "pathway_10093654", "reactome": "R-BTA-434316", "name": "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion", "reactions": [ "reaction_10047809" ] }, "R-BTA-448424": { "id": "pathway_10093064", "reactome": "R-BTA-448424", "name": "Interleukin-17 signaling", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-6806667": { "id": "pathway_10092950", "reactome": "R-BTA-6806667", "name": "Metabolism of fat-soluble vitamins", "reactions": [ "reaction_10085855", "reaction_10038427", "reaction_10054382", "reaction_10065445", "reaction_10069948", "reaction_10054404", "reaction_10066247", "reaction_10090493", "reaction_10065437", "reaction_10070971", "reaction_10081928", "reaction_10054393", "reaction_10081935", "reaction_10085853", "reaction_10065441", "reaction_10054375", "reaction_10066249", "reaction_10054395" ] }, "R-BTA-5357905": { "id": "pathway_10094356", "reactome": "R-BTA-5357905", "name": "Regulation of TNFR1 signaling", "reactions": [ "reaction_10092031", "reaction_10071541", "reaction_10071534", "reaction_10067895", "reaction_10084723", "reaction_10092026" ] }, "R-BTA-420499": { "id": "pathway_10093504", "reactome": "R-BTA-420499", "name": "Class C/3 (Metabotropic glutamate/pheromone receptors)", "reactions": [ "reaction_10049643", "reaction_10067348", "reaction_10045138" ] }, "R-BTA-9013973": { "id": "pathway_10093076", "reactome": "R-BTA-9013973", "name": "TICAM1-dependent activation of IRF3/IRF7", "reactions": [ "reaction_10040197", "reaction_10039560" ] }, "R-BTA-1483166": { "id": "pathway_10092666", "reactome": "R-BTA-1483166", "name": "Synthesis of PA", "reactions": [ "reaction_10059114", "reaction_10035812", "reaction_10058908", "reaction_10077777", "reaction_10058923", "reaction_10051264", "reaction_10086248", "reaction_10059860", "reaction_10058858", "reaction_10058834", "reaction_10035786", "reaction_10088649", "reaction_10058896" ] }, "R-BTA-8955332": { "id": "pathway_10094794", "reactome": "R-BTA-8955332", "name": "Carboxyterminal post-translational modifications of tubulin", "reactions": [ "reaction_10085250", "reaction_10085101" ] }, "R-BTA-9006936": { "id": "pathway_10093336", "reactome": "R-BTA-9006936", "name": "Signaling by TGFB family members", "reactions": [ "reaction_10064933", "reaction_10084542", "reaction_10056356", "reaction_10043311", "reaction_10056354", "reaction_10042976", "reaction_10071262" ] }, "R-BTA-4641257": { "id": "pathway_10094370", "reactome": "R-BTA-4641257", "name": "Degradation of AXIN", "reactions": [ "reaction_10068086", "reaction_10068088", "reaction_10068078", "reaction_10068073" ] }, "R-BTA-8849474": { "id": "pathway_10094728", "reactome": "R-BTA-8849474", "name": "PTK6 Activates STAT3", "reactions": [ "reaction_10083487" ] }, "R-BTA-211958": { "id": "pathway_10093436", "reactome": "R-BTA-211958", "name": "Miscellaneous substrates", "reactions": [ "reaction_10044235", "reaction_10044255", "reaction_10044247", "reaction_10044158", "reaction_10044242" ] }, "R-BTA-69580": { "id": "pathway_10092446", "reactome": "R-BTA-69580", "name": "p53-Dependent G1/S DNA damage checkpoint", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-418038": { "id": "pathway_10093660", "reactome": "R-BTA-418038", "name": "Nucleotide-like (purinergic) receptors", "reactions": [ "reaction_10047866", "reaction_10047870", "reaction_10047868", "reaction_10048003", "reaction_10047862", "reaction_10047864", "reaction_10047851", "reaction_10047853", "reaction_10047989", "reaction_10047987", "reaction_10047857", "reaction_10090956", "reaction_10047860" ] }, "R-BTA-8934903": { "id": "pathway_10094832", "reactome": "R-BTA-8934903", "name": "Receptor Mediated Mitophagy", "reactions": [ "reaction_10088891", "reaction_10087615", "reaction_10087621" ] }, "R-BTA-1538133": { "id": "pathway_10094074", "reactome": "R-BTA-1538133", "name": "G0 and Early G1", "reactions": [ "reaction_10057808", "reaction_10057804", "reaction_10057812", "reaction_10057800" ] }, "R-BTA-456926": { "id": "pathway_10092838", "reactome": "R-BTA-456926", "name": "Thrombin signalling through proteinase activated receptors (PARs)", "reactions": [ "reaction_10092299", "reaction_10047886", "reaction_10047880", "reaction_10037433", "reaction_10037353", "reaction_10037580" ] }, "R-BTA-193775": { "id": "pathway_10093242", "reactome": "R-BTA-193775", "name": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol", "reactions": [ "reaction_10041337", "reaction_10041343", "reaction_10041363", "reaction_10041357", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041349", "reaction_10041351", "reaction_10041335", "reaction_10041193", "reaction_10041353", "reaction_10041361", "reaction_10041345", "reaction_10041367", "reaction_10041339", "reaction_10041217" ] }, "R-BTA-8849472": { "id": "pathway_10094742", "reactome": "R-BTA-8849472", "name": "PTK6 Down-Regulation", "reactions": [ "reaction_10083707", "reaction_10083729", "reaction_10083726" ] }, "R-BTA-5676590": { "id": "pathway_10094464", "reactome": "R-BTA-5676590", "name": "NIK-->noncanonical NF-kB signaling", "reactions": [ "reaction_10073708", "reaction_10071948", "reaction_10072030", "reaction_10071975", "reaction_10071982" ] }, "R-BTA-2980767": { "id": "pathway_10094318", "reactome": "R-BTA-2980767", "name": "Activation of NIMA Kinases NEK9, NEK6, NEK7", "reactions": [ "reaction_10066345", "reaction_10066324" ] }, "R-BTA-1266738": { "id": "pathway_10093388", "reactome": "R-BTA-1266738", "name": "Developmental Biology", "reactions": [ "reaction_10081917", "reaction_10081921", "reaction_10084311", "reaction_10089713", "reaction_10048951", "reaction_10045244", "reaction_10069146", "reaction_10083835", "reaction_10091007", "reaction_10047763", "reaction_10083824", "reaction_10084141", "reaction_10074613", "reaction_10085757", "reaction_10084153", "reaction_10074641", "reaction_10047735", "reaction_10069221", "reaction_10069157", "reaction_10069223", "reaction_10044090", "reaction_10045509", "reaction_10047618", "reaction_10069188", "reaction_10084135", "reaction_10084309", "reaction_10069418", "reaction_10045517", "reaction_10084393", "reaction_10043671", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10047455", "reaction_10047659", "reaction_10047717", "reaction_10084326", "reaction_10069285", "reaction_10084330", "reaction_10045224", "reaction_10083741", "reaction_10084187", "reaction_10045236", "reaction_10050085", "reaction_10047449", "reaction_10069192", "reaction_10069121", "reaction_10089397", "reaction_10091009", "reaction_10084185", "reaction_10069159", "reaction_10084379", "reaction_10084131", "reaction_10083743", "reaction_10085755", "reaction_10084149", "reaction_10082871", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10069435", "reaction_10069144", "reaction_10077943", "reaction_10047458", "reaction_10069131", "reaction_10084196", "reaction_10069226", "reaction_10050116", "reaction_10081857", "reaction_10049024", "reaction_10074603", "reaction_10090179", "reaction_10081915", "reaction_10081861", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10047753", "reaction_10084194", "reaction_10084313" ] }, "R-BTA-480985": { "id": "pathway_10094698", "reactome": "R-BTA-480985", "name": "Synthesis of dolichyl-phosphate-glucose", "reactions": [ "reaction_10082941" ] }, "R-BTA-5358508": { "id": "pathway_10094452", "reactome": "R-BTA-5358508", "name": "Mismatch Repair", "reactions": [ "reaction_10071628", "reaction_10071769", "reaction_10071630", "reaction_10071765", "reaction_10071767", "reaction_10071622", "reaction_10071638", "reaction_10071640", "reaction_10071617", "reaction_10071607" ] }, "R-BTA-397014": { "id": "pathway_10093604", "reactome": "R-BTA-397014", "name": "Muscle contraction", "reactions": [ "reaction_10048504", "reaction_10047186", "reaction_10057418", "reaction_10071819", "reaction_10047200", "reaction_10077468", "reaction_10071843", "reaction_10047893", "reaction_10071824", "reaction_10053180", "reaction_10048787", "reaction_10071800", "reaction_10091759", "reaction_10071876", "reaction_10047198", "reaction_10047196" ] }, "R-BTA-201681": { "id": "pathway_10093346", "reactome": "R-BTA-201681", "name": "TCF dependent signaling in response to WNT", "reactions": [ "reaction_10068078", "reaction_10068073", "reaction_10068704", "reaction_10069645", "reaction_10067879", "reaction_10067694", "reaction_10069664", "reaction_10067698", "reaction_10068088", "reaction_10071320", "reaction_10068707", "reaction_10069607", "reaction_10069647", "reaction_10068086", "reaction_10071330", "reaction_10068095", "reaction_10067696", "reaction_10059152", "reaction_10043129" ] }, "R-BTA-2453902": { "id": "pathway_10092632", "reactome": "R-BTA-2453902", "name": "The canonical retinoid cycle in rods (twilight vision)", "reactions": [ "reaction_10065597", "reaction_10088914", "reaction_10035558", "reaction_10035579", "reaction_10065644", "reaction_10035406", "reaction_10065606", "reaction_10065646", "reaction_10077751", "reaction_10065604" ] }, "R-BTA-442380": { "id": "pathway_10093766", "reactome": "R-BTA-442380", "name": "Zinc influx into cells by the SLC39 gene family", "reactions": [ "reaction_10049440", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-5223345": { "id": "pathway_10094434", "reactome": "R-BTA-5223345", "name": "Miscellaneous transport and binding events", "reactions": [ "reaction_10070735", "reaction_10071469", "reaction_10071476", "reaction_10071462", "reaction_10071280", "reaction_10087365", "reaction_10071490", "reaction_10086343" ] }, "R-BTA-392154": { "id": "pathway_10093674", "reactome": "R-BTA-392154", "name": "Nitric oxide stimulates guanylate cyclase", "reactions": [ "reaction_10047907", "reaction_10047930" ] }, "R-BTA-5221030": { "id": "pathway_10094432", "reactome": "R-BTA-5221030", "name": "TET1,2,3 and TDG demethylate DNA", "reactions": [ "reaction_10070700", "reaction_10070702" ] }, "R-BTA-170984": { "id": "pathway_10093078", "reactome": "R-BTA-170984", "name": "ARMS-mediated activation", "reactions": [ "reaction_10039592", "reaction_10039601", "reaction_10039581" ] }, "R-BTA-198203": { "id": "pathway_10093296", "reactome": "R-BTA-198203", "name": "PI3K/AKT activation", "reactions": [ "reaction_10041851", "reaction_10043315", "reaction_10041869" ] }, "R-BTA-1660662": { "id": "pathway_10094120", "reactome": "R-BTA-1660662", "name": "Glycosphingolipid metabolism", "reactions": [ "reaction_10060021", "reaction_10059977", "reaction_10059944", "reaction_10060109", "reaction_10059984", "reaction_10084410", "reaction_10059951", "reaction_10059961", "reaction_10060041", "reaction_10060012", "reaction_10071483", "reaction_10059991", "reaction_10060302", "reaction_10060316", "reaction_10059954", "reaction_10059968", "reaction_10071497", "reaction_10060309" ] }, "R-BTA-2393930": { "id": "pathway_10094284", "reactome": "R-BTA-2393930", "name": "Phosphate bond hydrolysis by NUDT proteins", "reactions": [ "reaction_10065378", "reaction_10065362", "reaction_10065371", "reaction_10065359", "reaction_10065381", "reaction_10065763", "reaction_10065760", "reaction_10065383", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10065386" ] }, "R-BTA-389513": { "id": "pathway_10093572", "reactome": "R-BTA-389513", "name": "CTLA4 inhibitory signaling", "reactions": [ "reaction_10046903", "reaction_10046909", "reaction_10046807", "reaction_10046959" ] }, "R-BTA-5624138": { "id": "pathway_10094496", "reactome": "R-BTA-5624138", "name": "Trafficking of myristoylated proteins to the cilium", "reactions": [ "reaction_10072497", "reaction_10072489" ] }, "R-BTA-68867": { "id": "pathway_10092398", "reactome": "R-BTA-68867", "name": "Assembly of the pre-replicative complex", "reactions": [ "reaction_10033379", "reaction_10033412" ] }, "R-BTA-170660": { "id": "pathway_10093100", "reactome": "R-BTA-170660", "name": "Adenylate cyclase activating pathway", "reactions": [ "reaction_10039674", "reaction_10039667", "reaction_10039658", "reaction_10039671" ] }, "R-BTA-390648": { "id": "pathway_10093610", "reactome": "R-BTA-390648", "name": "Muscarinic acetylcholine receptors", "reactions": [ "reaction_10047214", "reaction_10047210" ] }, "R-BTA-1483191": { "id": "pathway_10093452", "reactome": "R-BTA-1483191", "name": "Synthesis of PC", "reactions": [ "reaction_10085808", "reaction_10044540", "reaction_10085798", "reaction_10059094", "reaction_10059141", "reaction_10086064", "reaction_10059063", "reaction_10085024", "reaction_10085788" ] }, "R-BTA-9026395": { "id": "pathway_10094938", "reactome": "R-BTA-9026395", "name": "Biosynthesis of DHA-derived sulfido conjugates", "reactions": [ "reaction_10090480", "reaction_10090491", "reaction_10090489" ] }, "R-BTA-351200": { "id": "pathway_10093476", "reactome": "R-BTA-351200", "name": "Interconversion of polyamines", "reactions": [ "reaction_10044837", "reaction_10044835" ] }, "R-BTA-399956": { "id": "pathway_10093648", "reactome": "R-BTA-399956", "name": "CRMPs in Sema3A signaling", "reactions": [ "reaction_10047735", "reaction_10047753", "reaction_10047717" ] }, "R-BTA-391903": { "id": "pathway_10093626", "reactome": "R-BTA-391903", "name": "Eicosanoid ligand-binding receptors", "reactions": [ "reaction_10047396", "reaction_10047378", "reaction_10047374", "reaction_10047394", "reaction_10047398", "reaction_10047366", "reaction_10047380", "reaction_10091763", "reaction_10047364", "reaction_10047376", "reaction_10091812" ] }, "R-BTA-209776": { "id": "pathway_10093410", "reactome": "R-BTA-209776", "name": "Metabolism of amine-derived hormones", "reactions": [ "reaction_10043956", "reaction_10043978", "reaction_10043980", "reaction_10044828", "reaction_10076360", "reaction_10043917", "reaction_10043933", "reaction_10043986", "reaction_10043924", "reaction_10043948" ] }, "R-BTA-6804756": { "id": "pathway_10092430", "reactome": "R-BTA-6804756", "name": "Regulation of TP53 Activity through Phosphorylation", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10081563", "reaction_10066870", "reaction_10081602", "reaction_10066670", "reaction_10081595", "reaction_10078731", "reaction_10066712", "reaction_10033535", "reaction_10076341", "reaction_10080730", "reaction_10081629", "reaction_10081622", "reaction_10066704", "reaction_10078720" ] }, "R-BTA-68882": { "id": "pathway_10094298", "reactome": "R-BTA-68882", "name": "Mitotic Anaphase", "reactions": [ "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10065708", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-193697": { "id": "pathway_10093268", "reactome": "R-BTA-193697", "name": "p75NTR regulates axonogenesis", "reactions": [ "reaction_10041470" ] }, "R-BTA-5673001": { "id": "pathway_10094568", "reactome": "R-BTA-5673001", "name": "RAF/MAP kinase cascade", "reactions": [ "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10091490", "reaction_10073904", "reaction_10091506", "reaction_10073932", "reaction_10074238", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10074088", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10073940", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-453276": { "id": "pathway_10092898", "reactome": "R-BTA-453276", "name": "Regulation of mitotic cell cycle", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-70921": { "id": "pathway_10092510", "reactome": "R-BTA-70921", "name": "Histidine catabolism", "reactions": [ "reaction_10054585", "reaction_10033849", "reaction_10033833", "reaction_10033840", "reaction_10077758", "reaction_10086033" ] }, "R-BTA-9035034": { "id": "pathway_10095024", "reactome": "R-BTA-9035034", "name": "RHOF GTPase cycle", "reactions": [ "reaction_10091921", "reaction_10091832", "reaction_10091864" ] }, "R-BTA-446219": { "id": "pathway_10093222", "reactome": "R-BTA-446219", "name": "Synthesis of substrates in N-glycan biosythesis", "reactions": [ "reaction_10069371", "reaction_10077823", "reaction_10082941", "reaction_10069320", "reaction_10069359", "reaction_10069357", "reaction_10081490", "reaction_10049818", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10069368", "reaction_10040933", "reaction_10069373", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10077826", "reaction_10049831", "reaction_10049778", "reaction_10081497", "reaction_10069348", "reaction_10050153", "reaction_10048958", "reaction_10077816", "reaction_10069382" ] }, "R-BTA-1483076": { "id": "pathway_10094112", "reactome": "R-BTA-1483076", "name": "Synthesis of CL", "reactions": [ "reaction_10059066" ] }, "R-BTA-71032": { "id": "pathway_10092522", "reactome": "R-BTA-71032", "name": "Propionyl-CoA catabolism", "reactions": [ "reaction_10033912", "reaction_10033896", "reaction_10033889" ] }, "R-BTA-212300": { "id": "pathway_10093440", "reactome": "R-BTA-212300", "name": "PRC2 methylates histones and DNA", "reactions": [ "reaction_10044333", "reaction_10044361", "reaction_10044381", "reaction_10044390" ] }, "R-BTA-532668": { "id": "pathway_10093956", "reactome": "R-BTA-532668", "name": "N-glycan trimming in the ER and Calnexin/Calreticulin cycle", "reactions": [ "reaction_10056058" ] }, "R-BTA-422085": { "id": "pathway_10093698", "reactome": "R-BTA-422085", "name": "Synthesis, secretion, and deacylation of Ghrelin", "reactions": [ "reaction_10048429", "reaction_10048461", "reaction_10048465", "reaction_10048407" ] }, "R-BTA-3214815": { "id": "pathway_10094376", "reactome": "R-BTA-3214815", "name": "HDACs deacetylate histones", "reactions": [ "reaction_10068725", "reaction_10091745", "reaction_10068844", "reaction_10068699" ] }, "R-BTA-5687128": { "id": "pathway_10094602", "reactome": "R-BTA-5687128", "name": "MAPK6/MAPK4 signaling", "reactions": [ "reaction_10075251", "reaction_10075253", "reaction_10076229", "reaction_10075256", "reaction_10075916", "reaction_10075906", "reaction_10075205", "reaction_10076198", "reaction_10075260", "reaction_10075223", "reaction_10076193", "reaction_10075218", "reaction_10075239", "reaction_10075262" ] }, "R-BTA-9707616": { "id": "pathway_10093890", "reactome": "R-BTA-9707616", "name": "Heme signaling", "reactions": [ "reaction_10092237", "reaction_10052914", "reaction_10092271", "reaction_10092227", "reaction_10092269", "reaction_10092225", "reaction_10092239", "reaction_10092214" ] }, "R-BTA-6804754": { "id": "pathway_10094688", "reactome": "R-BTA-6804754", "name": "Regulation of TP53 Expression", "reactions": [ "reaction_10081561" ] }, "R-BTA-157579": { "id": "pathway_10092964", "reactome": "R-BTA-157579", "name": "Telomere Maintenance", "reactions": [ "reaction_10038947", "reaction_10091663", "reaction_10038540", "reaction_10091685", "reaction_10038949", "reaction_10038534" ] }, "R-BTA-5666185": { "id": "pathway_10094556", "reactome": "R-BTA-5666185", "name": "RHO GTPases Activate Rhotekin and Rhophilins", "reactions": [ "reaction_10073577" ] }, "R-BTA-109704": { "id": "pathway_10092734", "reactome": "R-BTA-109704", "name": "PI3K Cascade", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10036570", "reaction_10036607" ] }, "R-BTA-8948216": { "id": "pathway_10094194", "reactome": "R-BTA-8948216", "name": "Collagen chain trimerization", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10087581", "reaction_10087567", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10062071", "reaction_10087569", "reaction_10087585", "reaction_10087565", "reaction_10087573", "reaction_10087579" ] }, "R-BTA-1170546": { "id": "pathway_10093936", "reactome": "R-BTA-1170546", "name": "Prolactin receptor signaling", "reactions": [ "reaction_10054524", "reaction_10056335", "reaction_10060412", "reaction_10057823", "reaction_10057836", "reaction_10054791", "reaction_10057834" ] }, "R-BTA-167826": { "id": "pathway_10093008", "reactome": "R-BTA-167826", "name": "The fatty acid cycling model", "reactions": [ "reaction_10039254", "reaction_10039240", "reaction_10039242" ] }, "R-BTA-419771": { "id": "pathway_10093694", "reactome": "R-BTA-419771", "name": "Opsins", "reactions": [ "reaction_10048208", "reaction_10048214" ] }, "R-BTA-350054": { "id": "pathway_10093444", "reactome": "R-BTA-350054", "name": "Notch-HLH transcription pathway", "reactions": [ "reaction_10044446", "reaction_10044726" ] }, "R-BTA-9708530": { "id": "pathway_10095040", "reactome": "R-BTA-9708530", "name": "Regulation of BACH1 activity", "reactions": [ "reaction_10092289", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10092239" ] }, "R-BTA-1299308": { "id": "pathway_10094054", "reactome": "R-BTA-1299308", "name": "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)", "reactions": [ "reaction_10057639" ] }, "R-BTA-72766": { "id": "pathway_10092570", "reactome": "R-BTA-72766", "name": "Translation", "reactions": [ "reaction_10038107", "reaction_10050169", "reaction_10034855", "reaction_10038082", "reaction_10034365", "reaction_10034383", "reaction_10034224", "reaction_10034387", "reaction_10060894", "reaction_10034905" ] }, "R-BTA-936964": { "id": "pathway_10093074", "reactome": "R-BTA-936964", "name": "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon", "reactions": [ "reaction_10040197", "reaction_10039560" ] }, "R-BTA-77350": { "id": "pathway_10092712", "reactome": "R-BTA-77350", "name": "Beta oxidation of hexanoyl-CoA to butanoyl-CoA", "reactions": [ "reaction_10036027" ] }, "R-BTA-2187335": { "id": "pathway_10094294", "reactome": "R-BTA-2187335", "name": "The retinoid cycle in cones (daylight vision)", "reactions": [ "reaction_10065677", "reaction_10065683", "reaction_10065664", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065673", "reaction_10065679", "reaction_10065675" ] }, "R-BTA-1679131": { "id": "pathway_10094162", "reactome": "R-BTA-1679131", "name": "Trafficking and processing of endosomal TLR", "reactions": [ "reaction_10060773", "reaction_10060759", "reaction_10060783", "reaction_10060785" ] }, "R-BTA-2559582": { "id": "pathway_10093142", "reactome": "R-BTA-2559582", "name": "Senescence-Associated Secretory Phenotype (SASP)", "reactions": [ "reaction_10040355", "reaction_10041950", "reaction_10068899" ] }, "R-BTA-1483115": { "id": "pathway_10094100", "reactome": "R-BTA-1483115", "name": "Hydrolysis of LPC", "reactions": [ "reaction_10058910", "reaction_10088026", "reaction_10058871" ] }, "R-BTA-5654699": { "id": "pathway_10094526", "reactome": "R-BTA-5654699", "name": "SHC-mediated cascade:FGFR2", "reactions": [ "reaction_10072999", "reaction_10073001", "reaction_10072993", "reaction_10073004" ] }, "R-BTA-5654736": { "id": "pathway_10093174", "reactome": "R-BTA-5654736", "name": "Signaling by FGFR1", "reactions": [ "reaction_10073326", "reaction_10073083", "reaction_10057327", "reaction_10073090", "reaction_10073108", "reaction_10072935", "reaction_10073106", "reaction_10073113", "reaction_10072920", "reaction_10073225", "reaction_10073087", "reaction_10073077", "reaction_10057314", "reaction_10057329", "reaction_10073122", "reaction_10073199", "reaction_10059156", "reaction_10040696", "reaction_10053082", "reaction_10073115", "reaction_10057318", "reaction_10040704", "reaction_10073228", "reaction_10087373", "reaction_10040794", "reaction_10073102", "reaction_10072957", "reaction_10040773", "reaction_10073097", "reaction_10073119", "reaction_10073071", "reaction_10040791", "reaction_10072937", "reaction_10073201", "reaction_10057323", "reaction_10057337", "reaction_10040860", "reaction_10057302" ] }, "R-BTA-1660661": { "id": "pathway_10093726", "reactome": "R-BTA-1660661", "name": "Sphingolipid de novo biosynthesis", "reactions": [ "reaction_10049182", "reaction_10048860", "reaction_10049154", "reaction_10076389", "reaction_10082058", "reaction_10049163", "reaction_10048986", "reaction_10048910", "reaction_10049161", "reaction_10049121", "reaction_10091936", "reaction_10048995", "reaction_10049116", "reaction_10048917", "reaction_10048889", "reaction_10049141", "reaction_10049004", "reaction_10049189", "reaction_10091941", "reaction_10048988", "reaction_10076833", "reaction_10049007", "reaction_10048903", "reaction_10048882", "reaction_10049143", "reaction_10048978", "reaction_10076151", "reaction_10048896" ] }, "R-BTA-5654219": { "id": "pathway_10094514", "reactome": "R-BTA-5654219", "name": "Phospholipase C-mediated cascade: FGFR1", "reactions": [ "reaction_10072920", "reaction_10072937", "reaction_10072935" ] }, "R-BTA-9037629": { "id": "pathway_10094972", "reactome": "R-BTA-9037629", "name": "Lewis blood group biosynthesis", "reactions": [ "reaction_10090799", "reaction_10090774", "reaction_10090867", "reaction_10090822", "reaction_10090797", "reaction_10090854", "reaction_10090772", "reaction_10090856", "reaction_10090851", "reaction_10090819", "reaction_10090802" ] }, "R-BTA-1433559": { "id": "pathway_10093396", "reactome": "R-BTA-1433559", "name": "Regulation of KIT signaling", "reactions": [ "reaction_10057867", "reaction_10043832" ] }, "R-BTA-1237044": { "id": "pathway_10094002", "reactome": "R-BTA-1237044", "name": "Erythrocytes take up carbon dioxide and release oxygen", "reactions": [ "reaction_10058790", "reaction_10057007", "reaction_10081968", "reaction_10057062" ] }, "R-BTA-70221": { "id": "pathway_10092470", "reactome": "R-BTA-70221", "name": "Glycogen breakdown (glycogenolysis)", "reactions": [ "reaction_10034118", "reaction_10034138", "reaction_10090696", "reaction_10033594", "reaction_10050637" ] }, "R-BTA-111448": { "id": "pathway_10092864", "reactome": "R-BTA-111448", "name": "Activation of NOXA and translocation to mitochondria", "reactions": [ "reaction_10037739" ] }, "R-BTA-9706369": { "id": "pathway_10095030", "reactome": "R-BTA-9706369", "name": "Negative regulation of FLT3", "reactions": [ "reaction_10092143", "reaction_10092147", "reaction_10092195", "reaction_10092183", "reaction_10092139", "reaction_10092173", "reaction_10092040", "reaction_10092141", "reaction_10092126" ] }, "R-BTA-195721": { "id": "pathway_10093272", "reactome": "R-BTA-195721", "name": "Signaling by WNT", "reactions": [ "reaction_10067128", "reaction_10069459", "reaction_10067124", "reaction_10069448", "reaction_10068078", "reaction_10068073", "reaction_10069882", "reaction_10068704", "reaction_10069896", "reaction_10069645", "reaction_10041637", "reaction_10067879", "reaction_10067694", "reaction_10069664", "reaction_10067698", "reaction_10063849", "reaction_10071356", "reaction_10068088", "reaction_10069876", "reaction_10041629", "reaction_10071320", "reaction_10068707", "reaction_10070931", "reaction_10066994", "reaction_10069607", "reaction_10087597", "reaction_10069595", "reaction_10041583", "reaction_10069647", "reaction_10068933", "reaction_10041604", "reaction_10068939", "reaction_10069593", "reaction_10068839", "reaction_10069299", "reaction_10068086", "reaction_10068837", "reaction_10063843", "reaction_10069651", "reaction_10069872", "reaction_10067204", "reaction_10041640", "reaction_10069456", "reaction_10071330", "reaction_10041647", "reaction_10068923", "reaction_10068095", "reaction_10067696", "reaction_10059152", "reaction_10067200", "reaction_10041606", "reaction_10067202", "reaction_10043129" ] }, "R-BTA-5218920": { "id": "pathway_10094278", "reactome": "R-BTA-5218920", "name": "VEGFR2 mediated vascular permeability", "reactions": [ "reaction_10065227" ] }, "R-BTA-438064": { "id": "pathway_10092796", "reactome": "R-BTA-438064", "name": "Post NMDA receptor activation events", "reactions": [ "reaction_10090547", "reaction_10091067", "reaction_10049478", "reaction_10091075", "reaction_10036981" ] }, "R-BTA-8853383": { "id": "pathway_10094676", "reactome": "R-BTA-8853383", "name": "Lysosomal oligosaccharide catabolism", "reactions": [ "reaction_10080747", "reaction_10084129", "reaction_10080756" ] }, "R-BTA-1482798": { "id": "pathway_10094106", "reactome": "R-BTA-1482798", "name": "Acyl chain remodeling of CL", "reactions": [ "reaction_10058998", "reaction_10058985", "reaction_10058993", "reaction_10058955" ] }, "R-BTA-112303": { "id": "pathway_10093516", "reactome": "R-BTA-112303", "name": "Electric Transmission Across Gap Junctions", "reactions": [ "reaction_10045444", "reaction_10045455", "reaction_10045466" ] }, "R-BTA-380972": { "id": "pathway_10093544", "reactome": "R-BTA-380972", "name": "Energy dependent regulation of mTOR by LKB1-AMPK", "reactions": [ "reaction_10046572", "reaction_10046583", "reaction_10049894", "reaction_10046588" ] }, "R-BTA-168138": { "id": "pathway_10093028", "reactome": "R-BTA-168138", "name": "Toll Like Receptor 9 (TLR9) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-8854214": { "id": "pathway_10094764", "reactome": "R-BTA-8854214", "name": "TBC/RABGAPs", "reactions": [ "reaction_10084238", "reaction_10084291", "reaction_10084276", "reaction_10084246", "reaction_10084261", "reaction_10084228" ] }, "R-BTA-111957": { "id": "pathway_10092806", "reactome": "R-BTA-111957", "name": "Cam-PDE 1 activation", "reactions": [ "reaction_10037022", "reaction_10037024" ] }, "R-BTA-389887": { "id": "pathway_10093594", "reactome": "R-BTA-389887", "name": "Beta-oxidation of pristanoyl-CoA", "reactions": [ "reaction_10047044", "reaction_10047042", "reaction_10047056", "reaction_10047033" ] }, "R-BTA-351143": { "id": "pathway_10093472", "reactome": "R-BTA-351143", "name": "Agmatine biosynthesis", "reactions": [ "reaction_10044801" ] }, "R-BTA-211897": { "id": "pathway_10092692", "reactome": "R-BTA-211897", "name": "Cytochrome P450 - arranged by substrate type", "reactions": [ "reaction_10044477", "reaction_10041177", "reaction_10043971", "reaction_10041412", "reaction_10044235", "reaction_10041386", "reaction_10035958", "reaction_10044182", "reaction_10044255", "reaction_10044242", "reaction_10044280", "reaction_10041415", "reaction_10044250", "reaction_10044223", "reaction_10044275", "reaction_10044204", "reaction_10035977", "reaction_10035878", "reaction_10044216", "reaction_10044225", "reaction_10044265", "reaction_10035911", "reaction_10041397", "reaction_10044167", "reaction_10071909", "reaction_10044247", "reaction_10044195", "reaction_10077751", "reaction_10035865", "reaction_10044218", "reaction_10043964", "reaction_10041393", "reaction_10041193", "reaction_10044151", "reaction_10044270", "reaction_10041277", "reaction_10044211", "reaction_10044480", "reaction_10044158", "reaction_10041500", "reaction_10041217", "reaction_10041206", "reaction_10044260", "reaction_10044232", "reaction_10044293", "reaction_10035861", "reaction_10041195" ] }, "R-BTA-975634": { "id": "pathway_10093924", "reactome": "R-BTA-975634", "name": "Retinoid metabolism and transport", "reactions": [ "reaction_10054382", "reaction_10065445", "reaction_10069948", "reaction_10054404", "reaction_10066249", "reaction_10065437", "reaction_10066247", "reaction_10054393", "reaction_10065441", "reaction_10054375", "reaction_10070971", "reaction_10054395" ] }, "R-BTA-141333": { "id": "pathway_10092888", "reactome": "R-BTA-141333", "name": "Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB", "reactions": [ "reaction_10038000" ] }, "R-BTA-190372": { "id": "pathway_10093188", "reactome": "R-BTA-190372", "name": "FGFR3c ligand binding and activation", "reactions": [ "reaction_10083933", "reaction_10040782", "reaction_10083935", "reaction_10040753" ] }, "R-BTA-1483213": { "id": "pathway_10094108", "reactome": "R-BTA-1483213", "name": "Synthesis of PE", "reactions": [ "reaction_10059130", "reaction_10059141", "reaction_10059082", "reaction_10076994", "reaction_10059150", "reaction_10059035" ] }, "R-BTA-1482883": { "id": "pathway_10094096", "reactome": "R-BTA-1482883", "name": "Acyl chain remodeling of DAG and TAG", "reactions": [ "reaction_10058892", "reaction_10058819", "reaction_10058948", "reaction_10059006", "reaction_10077004", "reaction_10058894", "reaction_10058961", "reaction_10083572" ] }, "R-BTA-163680": { "id": "pathway_10092988", "reactome": "R-BTA-163680", "name": "AMPK inhibits chREBP transcriptional activation activity", "reactions": [ "reaction_10083614", "reaction_10038938" ] }, "R-BTA-74752": { "id": "pathway_10092644", "reactome": "R-BTA-74752", "name": "Signaling by Insulin receptor", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10035536", "reaction_10036570", "reaction_10075097", "reaction_10035507", "reaction_10036607", "reaction_10036616", "reaction_10075065" ] }, "R-BTA-2025928": { "id": "pathway_10095022", "reactome": "R-BTA-2025928", "name": "Calcineurin activates NFAT", "reactions": [ "reaction_10091817" ] }, "R-BTA-9014826": { "id": "pathway_10094730", "reactome": "R-BTA-9014826", "name": "Interleukin-36 pathway", "reactions": [ "reaction_10087338", "reaction_10083522" ] }, "R-BTA-500657": { "id": "pathway_10093826", "reactome": "R-BTA-500657", "name": "Presynaptic function of Kainate receptors", "reactions": [ "reaction_10051085" ] }, "R-BTA-202670": { "id": "pathway_10093322", "reactome": "R-BTA-202670", "name": "ERKs are inactivated", "reactions": [ "reaction_10042826", "reaction_10043488" ] }, "R-BTA-1660517": { "id": "pathway_10094152", "reactome": "R-BTA-1660517", "name": "Synthesis of PIPs at the late endosome membrane", "reactions": [ "reaction_10060537", "reaction_10060468", "reaction_10060553" ] }, "R-BTA-1266695": { "id": "pathway_10094792", "reactome": "R-BTA-1266695", "name": "Interleukin-7 signaling", "reactions": [ "reaction_10089253", "reaction_10085017", "reaction_10089251", "reaction_10091731" ] }, "R-BTA-420092": { "id": "pathway_10092982", "reactome": "R-BTA-420092", "name": "Glucagon-type ligand receptors", "reactions": [ "reaction_10048304", "reaction_10048248", "reaction_10038918", "reaction_10048282" ] }, "R-BTA-1251985": { "id": "pathway_10094020", "reactome": "R-BTA-1251985", "name": "Nuclear signaling by ERBB4", "reactions": [ "reaction_10057236", "reaction_10057286", "reaction_10057298", "reaction_10057272", "reaction_10057284", "reaction_10057252" ] }, "R-BTA-422475": { "id": "pathway_10093384", "reactome": "R-BTA-422475", "name": "Axon guidance", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10084393", "reaction_10084185", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-2682334": { "id": "pathway_10094388", "reactome": "R-BTA-2682334", "name": "EPH-Ephrin signaling", "reactions": [ "reaction_10069285", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10069146", "reaction_10069418", "reaction_10069131", "reaction_10069192", "reaction_10069253", "reaction_10069121", "reaction_10069144", "reaction_10069188", "reaction_10069221", "reaction_10069435", "reaction_10069226", "reaction_10069159", "reaction_10069157", "reaction_10069223" ] }, "R-BTA-75893": { "id": "pathway_10092880", "reactome": "R-BTA-75893", "name": "TNF signaling", "reactions": [ "reaction_10071556", "reaction_10071524", "reaction_10071526", "reaction_10092031", "reaction_10071541", "reaction_10071534", "reaction_10067895", "reaction_10084723", "reaction_10037964", "reaction_10092026", "reaction_10067908" ] }, "R-BTA-3214841": { "id": "pathway_10094410", "reactome": "R-BTA-3214841", "name": "PKMTs methylate histone lysines", "reactions": [ "reaction_10072790", "reaction_10070962", "reaction_10069846", "reaction_10072788", "reaction_10072655", "reaction_10069838", "reaction_10072778", "reaction_10072823", "reaction_10069939", "reaction_10072813", "reaction_10072755", "reaction_10072752", "reaction_10069937", "reaction_10072750", "reaction_10072725" ] }, "R-BTA-888593": { "id": "pathway_10093486", "reactome": "R-BTA-888593", "name": "Reuptake of GABA", "reactions": [ "reaction_10044941", "reaction_10049583" ] }, "R-BTA-195258": { "id": "pathway_10093366", "reactome": "R-BTA-195258", "name": "RHO GTPase Effectors", "reactions": [ "reaction_10091169", "reaction_10073549", "reaction_10091180", "reaction_10073796", "reaction_10073716", "reaction_10073806", "reaction_10073507", "reaction_10063374", "reaction_10073842", "reaction_10072515", "reaction_10073503", "reaction_10073557", "reaction_10063353", "reaction_10073755", "reaction_10073525", "reaction_10073547", "reaction_10068933", "reaction_10068939", "reaction_10073493", "reaction_10073577", "reaction_10073731", "reaction_10073569", "reaction_10073561", "reaction_10091175", "reaction_10043461", "reaction_10073559" ] }, "R-BTA-110362": { "id": "pathway_10094848", "reactome": "R-BTA-110362", "name": "POLB-Dependent Long Patch Base Excision Repair", "reactions": [ "reaction_10088526" ] }, "R-BTA-418457": { "id": "pathway_10093678", "reactome": "R-BTA-418457", "name": "cGMP effects", "reactions": [ "reaction_10047930" ] }, "R-BTA-111447": { "id": "pathway_10092856", "reactome": "R-BTA-111447", "name": "Activation of BAD and translocation to mitochondria ", "reactions": [ "reaction_10037630", "reaction_10037674", "reaction_10037678" ] }, "R-BTA-418359": { "id": "pathway_10093664", "reactome": "R-BTA-418359", "name": "Reduction of cytosolic Ca++ levels", "reactions": [ "reaction_10047893", "reaction_10048504", "reaction_10047900" ] }, "R-BTA-114508": { "id": "pathway_10093704", "reactome": "R-BTA-114508", "name": "Effects of PIP2 hydrolysis", "reactions": [ "reaction_10076743", "reaction_10048580", "reaction_10048543", "reaction_10048587", "reaction_10048632", "reaction_10048660" ] }, "R-BTA-936440": { "id": "pathway_10093914", "reactome": "R-BTA-936440", "name": "Negative regulators of DDX58/IFIH1 signaling", "reactions": [ "reaction_10053122", "reaction_10053095", "reaction_10053134" ] }, "R-BTA-8939902": { "id": "pathway_10094824", "reactome": "R-BTA-8939902", "name": "Regulation of RUNX2 expression and activity", "reactions": [ "reaction_10089681", "reaction_10089679", "reaction_10086716", "reaction_10086724" ] }, "R-BTA-8851680": { "id": "pathway_10094750", "reactome": "R-BTA-8851680", "name": "Butyrophilin (BTN) family interactions", "reactions": [ "reaction_10083959", "reaction_10083967" ] }, "R-BTA-1483206": { "id": "pathway_10092668", "reactome": "R-BTA-1483206", "name": "Glycerophospholipid biosynthesis", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10035786", "reaction_10058913", "reaction_10085808", "reaction_10058998", "reaction_10085798", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10084526", "reaction_10071344", "reaction_10059035", "reaction_10058996", "reaction_10058970", "reaction_10059018", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10058834", "reaction_10085340", "reaction_10058874", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10059073", "reaction_10059114", "reaction_10058892", "reaction_10059014", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10085024", "reaction_10058899", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10086064", "reaction_10058980", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10058841", "reaction_10059026", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10059101", "reaction_10058948", "reaction_10058985", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10076824" ] }, "R-BTA-9619665": { "id": "pathway_10094980", "reactome": "R-BTA-9619665", "name": "EGR2 and SOX10-mediated initiation of Schwann cell myelination", "reactions": [ "reaction_10091007", "reaction_10091009" ] }, "R-BTA-1296061": { "id": "pathway_10094032", "reactome": "R-BTA-1296061", "name": "HCN channels", "reactions": [ "reaction_10057390", "reaction_10057607" ] }, "R-BTA-8866652": { "id": "pathway_10094752", "reactome": "R-BTA-8866652", "name": "Synthesis of active ubiquitin: roles of E1 and E2 enzymes", "reactions": [ "reaction_10084122", "reaction_10084008", "reaction_10084113", "reaction_10084117" ] }, "R-BTA-2428933": { "id": "pathway_10094594", "reactome": "R-BTA-2428933", "name": "SHC-related events triggered by IGF1R", "reactions": [ "reaction_10075063" ] }, "R-BTA-166016": { "id": "pathway_10093000", "reactome": "R-BTA-166016", "name": "Toll Like Receptor 4 (TLR4) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10039560", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10039217", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-211163": { "id": "pathway_10093424", "reactome": "R-BTA-211163", "name": "AKT-mediated inactivation of FOXO1A", "reactions": [ "reaction_10044090" ] }, "R-BTA-433137": { "id": "pathway_10093754", "reactome": "R-BTA-433137", "name": "Sodium-coupled sulphate, di- and tri-carboxylate transporters", "reactions": [ "reaction_10049326", "reaction_10049333" ] }, "R-BTA-389357": { "id": "pathway_10093582", "reactome": "R-BTA-389357", "name": "CD28 dependent PI3K/Akt signaling", "reactions": [ "reaction_10065227", "reaction_10046932", "reaction_10047530" ] }, "R-BTA-549132": { "id": "pathway_10093832", "reactome": "R-BTA-549132", "name": "Organic cation/anion/zwitterion transport", "reactions": [ "reaction_10051305", "reaction_10051314", "reaction_10051283", "reaction_10051307", "reaction_10051325", "reaction_10051286", "reaction_10051269", "reaction_10051276" ] }, "R-BTA-9020933": { "id": "pathway_10093782", "reactome": "R-BTA-9020933", "name": "Interleukin-23 signaling", "reactions": [ "reaction_10049928", "reaction_10088498", "reaction_10087789", "reaction_10087697" ] }, "R-BTA-2454202": { "id": "pathway_10093050", "reactome": "R-BTA-2454202", "name": "Fc epsilon receptor (FCERI) signaling", "reactions": [ "reaction_10066151", "reaction_10066059", "reaction_10066144", "reaction_10066102", "reaction_10066080", "reaction_10050208", "reaction_10066052", "reaction_10066094", "reaction_10066141", "reaction_10039508", "reaction_10066147", "reaction_10050256", "reaction_10043225", "reaction_10066120", "reaction_10066172", "reaction_10065642", "reaction_10066065", "reaction_10043182", "reaction_10066168", "reaction_10066082", "reaction_10066127", "reaction_10065491", "reaction_10066180" ] }, "R-BTA-8953897": { "id": "pathway_10092556", "reactome": "R-BTA-8953897", "name": "Cellular responses to external stimuli", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10073468", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10073460", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10073446", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10073481", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273", "reaction_10073464" ] }, "R-BTA-2046104": { "id": "pathway_10094218", "reactome": "R-BTA-2046104", "name": "alpha-linolenic (omega3) and linoleic (omega6) acid metabolism", "reactions": [ "reaction_10063440", "reaction_10063450", "reaction_10063454", "reaction_10063413", "reaction_10063456", "reaction_10063442", "reaction_10063570", "reaction_10063446", "reaction_10063448", "reaction_10063428", "reaction_10063430", "reaction_10063437", "reaction_10063420", "reaction_10063444", "reaction_10063425", "reaction_10063452", "reaction_10063573" ] }, "R-BTA-991365": { "id": "pathway_10093094", "reactome": "R-BTA-991365", "name": "Activation of GABAB receptors", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-446193": { "id": "pathway_10093224", "reactome": "R-BTA-446193", "name": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein", "reactions": [ "reaction_10069371", "reaction_10077823", "reaction_10082941", "reaction_10069320", "reaction_10049797", "reaction_10069359", "reaction_10049860", "reaction_10069357", "reaction_10049789", "reaction_10081490", "reaction_10049818", "reaction_10049811", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10049867", "reaction_10069368", "reaction_10040933", "reaction_10069373", "reaction_10049858", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10077826", "reaction_10049831", "reaction_10049851", "reaction_10049778", "reaction_10081497", "reaction_10069348", "reaction_10049844", "reaction_10050153", "reaction_10048958", "reaction_10077816", "reaction_10069382" ] }, "R-BTA-5685939": { "id": "pathway_10094606", "reactome": "R-BTA-5685939", "name": "HDR through MMEJ (alt-NHEJ)", "reactions": [ "reaction_10075306", "reaction_10075326", "reaction_10075304", "reaction_10075323", "reaction_10075319" ] }, "R-BTA-8981373": { "id": "pathway_10094808", "reactome": "R-BTA-8981373", "name": "Intestinal hexose absorption", "reactions": [ "reaction_10086350" ] }, "R-BTA-2467813": { "id": "pathway_10094296", "reactome": "R-BTA-2467813", "name": "Separation of Sister Chromatids", "reactions": [ "reaction_10065708", "reaction_10065726" ] }, "R-BTA-1296065": { "id": "pathway_10094026", "reactome": "R-BTA-1296065", "name": "Inwardly rectifying K+ channels", "reactions": [ "reaction_10057399", "reaction_10057350", "reaction_10057418" ] }, "R-BTA-69017": { "id": "pathway_10092416", "reactome": "R-BTA-69017", "name": "CDK-mediated phosphorylation and removal of Cdc6", "reactions": [ "reaction_10033473" ] }, "R-BTA-194313": { "id": "pathway_10093264", "reactome": "R-BTA-194313", "name": "VEGF ligand-receptor interactions", "reactions": [ "reaction_10041463", "reaction_10041649", "reaction_10041453" ] }, "R-BTA-166658": { "id": "pathway_10093022", "reactome": "R-BTA-166658", "name": "Complement cascade", "reactions": [ "reaction_10054736", "reaction_10039465", "reaction_10054649", "reaction_10054494", "reaction_10055971", "reaction_10084020", "reaction_10087797", "reaction_10039778", "reaction_10066238", "reaction_10090400", "reaction_10039782", "reaction_10054678" ] }, "R-BTA-397795": { "id": "pathway_10093360", "reactome": "R-BTA-397795", "name": "G-protein beta:gamma signalling", "reactions": [ "reaction_10047498", "reaction_10088962", "reaction_10043315" ] }, "R-BTA-73943": { "id": "pathway_10094774", "reactome": "R-BTA-73943", "name": "Reversal of alkylation damage by DNA dioxygenases", "reactions": [ "reaction_10084497" ] }, "R-BTA-8877627": { "id": "pathway_10094796", "reactome": "R-BTA-8877627", "name": "Vitamin E", "reactions": [ "reaction_10085855", "reaction_10085853" ] }, "R-BTA-450341": { "id": "pathway_10093056", "reactome": "R-BTA-450341", "name": "Activation of the AP-1 family of transcription factors", "reactions": [ "reaction_10050208", "reaction_10039508" ] }, "R-BTA-2132295": { "id": "pathway_10094224", "reactome": "R-BTA-2132295", "name": "MHC class II antigen presentation", "reactions": [ "reaction_10065011", "reaction_10064118", "reaction_10065009", "reaction_10064219", "reaction_10065051", "reaction_10065055", "reaction_10064214", "reaction_10063972", "reaction_10065019", "reaction_10084401", "reaction_10064277", "reaction_10064221", "reaction_10064068", "reaction_10065021" ] }, "R-BTA-5576894": { "id": "pathway_10094460", "reactome": "R-BTA-5576894", "name": "Phase 1 - inactivation of fast Na+ channels", "reactions": [ "reaction_10071819" ] }, "R-BTA-5690714": { "id": "pathway_10094614", "reactome": "R-BTA-5690714", "name": "CD22 mediated BCR regulation", "reactions": [ "reaction_10075923" ] }, "R-BTA-448706": { "id": "pathway_10093790", "reactome": "R-BTA-448706", "name": "Interleukin-1 processing", "reactions": [ "reaction_10050011", "reaction_10050028", "reaction_10050024" ] }, "R-BTA-3928664": { "id": "pathway_10094394", "reactome": "R-BTA-3928664", "name": "Ephrin signaling", "reactions": [ "reaction_10069418", "reaction_10069192", "reaction_10069188", "reaction_10069221", "reaction_10069226", "reaction_10069223" ] }, "R-BTA-5173105": { "id": "pathway_10093886", "reactome": "R-BTA-5173105", "name": "O-linked glycosylation", "reactions": [ "reaction_10052546", "reaction_10052690", "reaction_10054550", "reaction_10070145", "reaction_10076773", "reaction_10077688", "reaction_10054766", "reaction_10061538", "reaction_10052521", "reaction_10052665", "reaction_10052606", "reaction_10052496", "reaction_10054722", "reaction_10054575", "reaction_10054773", "reaction_10052716", "reaction_10052461" ] }, "R-BTA-196757": { "id": "pathway_10093294", "reactome": "R-BTA-196757", "name": "Metabolism of folate and pterines", "reactions": [ "reaction_10042936", "reaction_10042922", "reaction_10041838", "reaction_10082078", "reaction_10081339", "reaction_10092306", "reaction_10041840", "reaction_10082068", "reaction_10081346", "reaction_10081349", "reaction_10086763", "reaction_10042940", "reaction_10076485", "reaction_10087442", "reaction_10042929" ] }, "R-BTA-381771": { "id": "pathway_10093560", "reactome": "R-BTA-381771", "name": "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)", "reactions": [ "reaction_10046723", "reaction_10048380" ] }, "R-BTA-9018683": { "id": "pathway_10094928", "reactome": "R-BTA-9018683", "name": "Biosynthesis of DPA-derived SPMs", "reactions": [ "reaction_10090474", "reaction_10090466", "reaction_10090477", "reaction_10090470", "reaction_10090472", "reaction_10090468" ] }, "R-BTA-917977": { "id": "pathway_10093888", "reactome": "R-BTA-917977", "name": "Transferrin endocytosis and recycling", "reactions": [ "reaction_10052907", "reaction_10076099", "reaction_10052901", "reaction_10052888", "reaction_10052909", "reaction_10052925", "reaction_10052911", "reaction_10052923" ] }, "R-BTA-417973": { "id": "pathway_10093682", "reactome": "R-BTA-417973", "name": "Adenosine P1 receptors", "reactions": [ "reaction_10048003", "reaction_10047987" ] }, "R-BTA-444821": { "id": "pathway_10093774", "reactome": "R-BTA-444821", "name": "Relaxin receptors", "reactions": [ "reaction_10049699", "reaction_10049683" ] }, "R-BTA-77588": { "id": "pathway_10092718", "reactome": "R-BTA-77588", "name": "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs", "reactions": [ "reaction_10036052", "reaction_10036076", "reaction_10036080" ] }, "R-BTA-9705462": { "id": "pathway_10095032", "reactome": "R-BTA-9705462", "name": "Inactivation of CSF3 (G-CSF) signaling", "reactions": [ "reaction_10092257", "reaction_10092108" ] }, "R-BTA-427601": { "id": "pathway_10093718", "reactome": "R-BTA-427601", "name": "Multifunctional anion exchangers", "reactions": [ "reaction_10048727", "reaction_10048768", "reaction_10048740", "reaction_10085967" ] }, "R-BTA-8963691": { "id": "pathway_10092538", "reactome": "R-BTA-8963691", "name": "Phenylalanine and tyrosine metabolism", "reactions": [ "reaction_10064346", "reaction_10033944", "reaction_10033935", "reaction_10033962", "reaction_10076974", "reaction_10033953", "reaction_10052040" ] }, "R-BTA-5686938": { "id": "pathway_10094686", "reactome": "R-BTA-5686938", "name": "Regulation of TLR by endogenous ligand", "reactions": [ "reaction_10081905", "reaction_10085369", "reaction_10081506", "reaction_10081510" ] }, "R-BTA-5685938": { "id": "pathway_10092676", "reactome": "R-BTA-5685938", "name": "HDR through Single Strand Annealing (SSA)", "reactions": [ "reaction_10075181", "reaction_10035846" ] }, "R-BTA-5654726": { "id": "pathway_10093910", "reactome": "R-BTA-5654726", "name": "Negative regulation of FGFR1 signaling", "reactions": [ "reaction_10059156", "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10073201", "reaction_10073199", "reaction_10057323", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-69239": { "id": "pathway_10092420", "reactome": "R-BTA-69239", "name": "Synthesis of DNA", "reactions": [ "reaction_10033473", "reaction_10033504", "reaction_10040183" ] }, "R-BTA-163316": { "id": "pathway_10092974", "reactome": "R-BTA-163316", "name": "Mitochondrial transcription termination", "reactions": [ "reaction_10038904" ] }, "R-BTA-190861": { "id": "pathway_10093206", "reactome": "R-BTA-190861", "name": "Gap junction assembly", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040842", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-983189": { "id": "pathway_10093946", "reactome": "R-BTA-983189", "name": "Kinesins", "reactions": [ "reaction_10055515", "reaction_10055829", "reaction_10055647", "reaction_10055645", "reaction_10055831", "reaction_10055827", "reaction_10055823", "reaction_10055833" ] }, "R-BTA-9018681": { "id": "pathway_10094914", "reactome": "R-BTA-9018681", "name": "Biosynthesis of protectins", "reactions": [ "reaction_10090460", "reaction_10090708", "reaction_10090386" ] }, "R-BTA-8856825": { "id": "pathway_10094778", "reactome": "R-BTA-8856825", "name": "Cargo recognition for clathrin-mediated endocytosis", "reactions": [ "reaction_10084824", "reaction_10084757", "reaction_10091753", "reaction_10085134", "reaction_10084822", "reaction_10085264", "reaction_10084819", "reaction_10085166", "reaction_10085116" ] }, "R-BTA-1912422": { "id": "pathway_10094184", "reactome": "R-BTA-1912422", "name": "Pre-NOTCH Expression and Processing", "reactions": [ "reaction_10090409", "reaction_10061449" ] }, "R-BTA-74749": { "id": "pathway_10094596", "reactome": "R-BTA-74749", "name": "Signal attenuation", "reactions": [ "reaction_10075065", "reaction_10075097" ] }, "R-BTA-8981607": { "id": "pathway_10094866", "reactome": "R-BTA-8981607", "name": "Intracellular oxygen transport", "reactions": [ "reaction_10089060", "reaction_10089058", "reaction_10089048", "reaction_10089062" ] }, "R-BTA-68689": { "id": "pathway_10092396", "reactome": "R-BTA-68689", "name": "CDC6 association with the ORC:origin complex", "reactions": [ "reaction_10033379" ] }, "R-BTA-8863795": { "id": "pathway_10094070", "reactome": "R-BTA-8863795", "name": "Downregulation of ERBB2 signaling", "reactions": [ "reaction_10057712", "reaction_10057735", "reaction_10057740", "reaction_10057719", "reaction_10061458", "reaction_10057742", "reaction_10057744", "reaction_10084849" ] }, "R-BTA-1222556": { "id": "pathway_10093676", "reactome": "R-BTA-1222556", "name": "ROS and RNS production in phagocytes", "reactions": [ "reaction_10084322", "reaction_10056531", "reaction_10077924", "reaction_10077921", "reaction_10047907", "reaction_10086405", "reaction_10077926", "reaction_10077919", "reaction_10077904" ] }, "R-BTA-5357956": { "id": "pathway_10094446", "reactome": "R-BTA-5357956", "name": "TNFR1-induced NFkappaB signaling pathway", "reactions": [ "reaction_10071556", "reaction_10071524", "reaction_10071526" ] }, "R-BTA-69186": { "id": "pathway_10092426", "reactome": "R-BTA-69186", "name": "Lagging Strand Synthesis", "reactions": [ "reaction_10033504" ] }, "R-BTA-111997": { "id": "pathway_10092786", "reactome": "R-BTA-111997", "name": "CaM pathway", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-190370": { "id": "pathway_10093170", "reactome": "R-BTA-190370", "name": "FGFR1b ligand binding and activation", "reactions": [ "reaction_10040791", "reaction_10040696" ] }, "R-BTA-1236394": { "id": "pathway_10093990", "reactome": "R-BTA-1236394", "name": "Signaling by ERBB4", "reactions": [ "reaction_10057177", "reaction_10057175", "reaction_10057236", "reaction_10057286", "reaction_10057184", "reaction_10057166", "reaction_10057264", "reaction_10057272", "reaction_10056781", "reaction_10057191", "reaction_10057298", "reaction_10057284", "reaction_10057262", "reaction_10057252", "reaction_10057151", "reaction_10090971", "reaction_10057188" ] }, "R-BTA-196783": { "id": "pathway_10093282", "reactome": "R-BTA-196783", "name": "Coenzyme A biosynthesis", "reactions": [ "reaction_10041756", "reaction_10042655", "reaction_10041765", "reaction_10041744", "reaction_10041737" ] }, "R-BTA-425407": { "id": "pathway_10092730", "reactome": "R-BTA-425407", "name": "SLC-mediated transmembrane transport", "reactions": [ "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10049371", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10049319", "reaction_10045494", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10049080", "reaction_10044978", "reaction_10051892", "reaction_10085907", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10045501", "reaction_10049464", "reaction_10045473", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10048795", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10051547", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10044962", "reaction_10072522", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10048504", "reaction_10049440", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10049083", "reaction_10048768", "reaction_10049378", "reaction_10049869", "reaction_10044941", "reaction_10048491", "reaction_10051276", "reaction_10044934", "reaction_10089029", "reaction_10049385", "reaction_10051545", "reaction_10044955", "reaction_10085384", "reaction_10051587", "reaction_10048754", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10036297", "reaction_10071001", "reaction_10051879", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10049053", "reaction_10048821", "reaction_10049628", "reaction_10049447", "reaction_10071003", "reaction_10051866", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-8985947": { "id": "pathway_10094872", "reactome": "R-BTA-8985947", "name": "Interleukin-9 signaling", "reactions": [ "reaction_10089736", "reaction_10089363", "reaction_10091731" ] }, "R-BTA-2142670": { "id": "pathway_10094246", "reactome": "R-BTA-2142670", "name": "Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)", "reactions": [ "reaction_10064526", "reaction_10064521" ] }, "R-BTA-140834": { "id": "pathway_10092876", "reactome": "R-BTA-140834", "name": "Extrinsic Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10037913", "reaction_10037906", "reaction_10037937", "reaction_10037899", "reaction_10037887", "reaction_10037915", "reaction_10037895" ] }, "R-BTA-418360": { "id": "pathway_10092850", "reactome": "R-BTA-418360", "name": "Platelet calcium homeostasis", "reactions": [ "reaction_10048504", "reaction_10037607", "reaction_10047893", "reaction_10048635", "reaction_10047900" ] }, "R-BTA-140342": { "id": "pathway_10093430", "reactome": "R-BTA-140342", "name": "Apoptosis induced DNA fragmentation", "reactions": [ "reaction_10044142", "reaction_10044116", "reaction_10044680", "reaction_10044146", "reaction_10044144" ] }, "R-BTA-918233": { "id": "pathway_10093958", "reactome": "R-BTA-918233", "name": "TRAF3-dependent IRF activation pathway", "reactions": [ "reaction_10056084", "reaction_10056082", "reaction_10056090" ] }, "R-BTA-69275": { "id": "pathway_10093088", "reactome": "R-BTA-69275", "name": "G2/M Transition", "reactions": [ "reaction_10039612", "reaction_10084043", "reaction_10084051", "reaction_10039614", "reaction_10084102", "reaction_10065938", "reaction_10066489", "reaction_10084090", "reaction_10084216", "reaction_10084214", "reaction_10084047", "reaction_10084206", "reaction_10084096", "reaction_10066487", "reaction_10084028" ] }, "R-BTA-8949613": { "id": "pathway_10094834", "reactome": "R-BTA-8949613", "name": "Cristae formation", "reactions": [ "reaction_10087635" ] }, "R-BTA-5668541": { "id": "pathway_10094466", "reactome": "R-BTA-5668541", "name": "TNFR2 non-canonical NF-kB pathway", "reactions": [ "reaction_10073699", "reaction_10076165", "reaction_10074266", "reaction_10074312", "reaction_10073708", "reaction_10071948", "reaction_10074318", "reaction_10072030", "reaction_10071975", "reaction_10074340", "reaction_10071982", "reaction_10073757", "reaction_10076237", "reaction_10073690", "reaction_10074320", "reaction_10074308", "reaction_10074316", "reaction_10074306", "reaction_10074310", "reaction_10073765", "reaction_10074280", "reaction_10074314" ] }, "R-BTA-5578775": { "id": "pathway_10093666", "reactome": "R-BTA-5578775", "name": "Ion homeostasis", "reactions": [ "reaction_10048504", "reaction_10047893", "reaction_10053180", "reaction_10048787", "reaction_10091759" ] }, "R-BTA-964739": { "id": "pathway_10093920", "reactome": "R-BTA-964739", "name": "N-glycan trimming and elongation in the cis-Golgi", "reactions": [ "reaction_10053317", "reaction_10053331", "reaction_10053337", "reaction_10053339", "reaction_10053324" ] }, "R-BTA-180786": { "id": "pathway_10092962", "reactome": "R-BTA-180786", "name": "Extension of Telomeres", "reactions": [ "reaction_10038947", "reaction_10091663", "reaction_10038540", "reaction_10038949", "reaction_10038534" ] }, "R-BTA-977606": { "id": "pathway_10093934", "reactome": "R-BTA-977606", "name": "Regulation of Complement cascade", "reactions": [ "reaction_10054649", "reaction_10054494", "reaction_10055971", "reaction_10084020", "reaction_10087797", "reaction_10066238", "reaction_10090400", "reaction_10054678" ] }, "R-BTA-170670": { "id": "pathway_10093092", "reactome": "R-BTA-170670", "name": "Adenylate cyclase inhibitory pathway", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-888568": { "id": "pathway_10093878", "reactome": "R-BTA-888568", "name": "GABA synthesis", "reactions": [ "reaction_10052013", "reaction_10051999" ] }, "R-BTA-975956": { "id": "pathway_10093892", "reactome": "R-BTA-975956", "name": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "reactions": [ "reaction_10052963" ] }, "R-BTA-174143": { "id": "pathway_10092896", "reactome": "R-BTA-174143", "name": "APC/C-mediated degradation of cell cycle proteins", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-451927": { "id": "pathway_10093820", "reactome": "R-BTA-451927", "name": "Interleukin-2 family signaling", "reactions": [ "reaction_10089736", "reaction_10089267", "reaction_10051194", "reaction_10052343", "reaction_10089311", "reaction_10089269", "reaction_10050619", "reaction_10050623", "reaction_10051196", "reaction_10089291", "reaction_10091731", "reaction_10052254", "reaction_10050527", "reaction_10089363", "reaction_10052337" ] }, "R-BTA-8849932": { "id": "pathway_10094746", "reactome": "R-BTA-8849932", "name": "Synaptic adhesion-like molecules", "reactions": [ "reaction_10083793", "reaction_10083789", "reaction_10084356" ] }, "R-BTA-8878159": { "id": "pathway_10094790", "reactome": "R-BTA-8878159", "name": "Transcriptional regulation by RUNX3", "reactions": [ "reaction_10086587", "reaction_10088006", "reaction_10087910", "reaction_10086581", "reaction_10088012", "reaction_10087900", "reaction_10088490", "reaction_10084947", "reaction_10088482", "reaction_10087862", "reaction_10086231", "reaction_10087997", "reaction_10087889", "reaction_10086241", "reaction_10086589" ] }, "R-BTA-9009391": { "id": "pathway_10094994", "reactome": "R-BTA-9009391", "name": "Extra-nuclear estrogen signaling", "reactions": [ "reaction_10091151", "reaction_10091260", "reaction_10091275", "reaction_10091158", "reaction_10091118", "reaction_10091271", "reaction_10091115", "reaction_10091267", "reaction_10091156" ] }, "R-BTA-69541": { "id": "pathway_10092442", "reactome": "R-BTA-69541", "name": "Stabilization of p53", "reactions": [ "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-176187": { "id": "pathway_10093124", "reactome": "R-BTA-176187", "name": "Activation of ATR in response to replication stress", "reactions": [ "reaction_10040059" ] }, "R-BTA-199991": { "id": "pathway_10093212", "reactome": "R-BTA-199991", "name": "Membrane Trafficking", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10084261", "reaction_10086209", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10083342", "reaction_10083767", "reaction_10040961", "reaction_10076778", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-2534343": { "id": "pathway_10094306", "reactome": "R-BTA-2534343", "name": "Interaction With Cumulus Cells And The Zona Pellucida", "reactions": [ "reaction_10065827" ] }, "R-BTA-140179": { "id": "pathway_10092890", "reactome": "R-BTA-140179", "name": "Amine Oxidase reactions", "reactions": [ "reaction_10038000" ] }, "R-BTA-419408": { "id": "pathway_10093692", "reactome": "R-BTA-419408", "name": "Lysosphingolipid and LPA receptors", "reactions": [ "reaction_10078536", "reaction_10048176", "reaction_10048180" ] }, "R-BTA-8847993": { "id": "pathway_10094722", "reactome": "R-BTA-8847993", "name": "ERBB2 Activates PTK6 Signaling", "reactions": [ "reaction_10083483", "reaction_10083477" ] }, "R-BTA-8874211": { "id": "pathway_10094798", "reactome": "R-BTA-8874211", "name": "CREB3 factors activate genes", "reactions": [ "reaction_10085865" ] }, "R-BTA-69560": { "id": "pathway_10094684", "reactome": "R-BTA-69560", "name": "Transcriptional activation of p53 responsive genes ", "reactions": [ "reaction_10081470" ] }, "R-BTA-888590": { "id": "pathway_10093488", "reactome": "R-BTA-888590", "name": "GABA synthesis, release, reuptake and degradation", "reactions": [ "reaction_10052013", "reaction_10051999", "reaction_10052018", "reaction_10044941", "reaction_10051989", "reaction_10049583" ] }, "R-BTA-9036866": { "id": "pathway_10093148", "reactome": "R-BTA-9036866", "name": "Expression and Processing of Neurotrophins", "reactions": [ "reaction_10040489", "reaction_10040495" ] }, "R-BTA-202433": { "id": "pathway_10093356", "reactome": "R-BTA-202433", "name": "Generation of second messenger molecules", "reactions": [ "reaction_10043262", "reaction_10043241" ] }, "R-BTA-983705": { "id": "pathway_10093968", "reactome": "R-BTA-983705", "name": "Signaling by the B Cell Receptor (BCR)", "reactions": [ "reaction_10091817", "reaction_10056239", "reaction_10075923" ] }, "R-BTA-2142712": { "id": "pathway_10094248", "reactome": "R-BTA-2142712", "name": "Synthesis of 12-eicosatetraenoic acid derivatives", "reactions": [ "reaction_10064534", "reaction_10064565", "reaction_10064554", "reaction_10064567" ] }, "R-BTA-1461973": { "id": "pathway_10094080", "reactome": "R-BTA-1461973", "name": "Defensins", "reactions": [ "reaction_10058486", "reaction_10061657", "reaction_10058492", "reaction_10058456", "reaction_10058388" ] }, "R-BTA-111996": { "id": "pathway_10092788", "reactome": "R-BTA-111996", "name": "Ca-dependent events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-1307965": { "id": "pathway_10094066", "reactome": "R-BTA-1307965", "name": "betaKlotho-mediated ligand binding", "reactions": [ "reaction_10057704", "reaction_10057707" ] }, "R-BTA-391160": { "id": "pathway_10093620", "reactome": "R-BTA-391160", "name": "Signal regulatory protein family interactions", "reactions": [ "reaction_10047292" ] }, "R-BTA-428643": { "id": "pathway_10093496", "reactome": "R-BTA-428643", "name": "Organic anion transporters", "reactions": [ "reaction_10049170", "reaction_10049173", "reaction_10045050", "reaction_10048958", "reaction_10048821", "reaction_10060218", "reaction_10085896", "reaction_10049083" ] }, "R-BTA-5654687": { "id": "pathway_10094516", "reactome": "R-BTA-5654687", "name": "Downstream signaling of activated FGFR1", "reactions": [ "reaction_10073326", "reaction_10073083", "reaction_10073090", "reaction_10073108", "reaction_10072935", "reaction_10073106", "reaction_10073113", "reaction_10072920", "reaction_10073225", "reaction_10073087", "reaction_10073122", "reaction_10073115", "reaction_10073228", "reaction_10087373", "reaction_10073102", "reaction_10072957", "reaction_10073097", "reaction_10073119", "reaction_10072937" ] }, "R-BTA-182971": { "id": "pathway_10093144", "reactome": "R-BTA-182971", "name": "EGFR downregulation", "reactions": [ "reaction_10040462", "reaction_10040460", "reaction_10040421", "reaction_10040393", "reaction_10040458", "reaction_10040432", "reaction_10040453", "reaction_10040369", "reaction_10040447", "reaction_10040451", "reaction_10040386" ] }, "R-BTA-201722": { "id": "pathway_10094352", "reactome": "R-BTA-201722", "name": "Formation of the beta-catenin:TCF transactivating complex", "reactions": [ "reaction_10067879" ] }, "R-BTA-5099900": { "id": "pathway_10094412", "reactome": "R-BTA-5099900", "name": "WNT5A-dependent internalization of FZD4", "reactions": [ "reaction_10069876", "reaction_10069882" ] }, "R-BTA-163125": { "id": "pathway_10092958", "reactome": "R-BTA-163125", "name": "Post-translational modification: synthesis of GPI-anchored proteins", "reactions": [ "reaction_10038464", "reaction_10038457" ] }, "R-BTA-77286": { "id": "pathway_10092706", "reactome": "R-BTA-77286", "name": "mitochondrial fatty acid beta-oxidation of saturated fatty acids", "reactions": [ "reaction_10036027", "reaction_10036023", "reaction_10036021", "reaction_10036042", "reaction_10036029", "reaction_10036025", "reaction_10036040", "reaction_10036012", "reaction_10036038" ] }, "R-BTA-71291": { "id": "pathway_10092486", "reactome": "R-BTA-71291", "name": "Metabolism of amino acids and derivatives", "reactions": [ "reaction_10060216", "reaction_10033849", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10076984", "reaction_10033778", "reaction_10090172", "reaction_10076459", "reaction_10052043", "reaction_10034004", "reaction_10043978", "reaction_10090175", "reaction_10051185", "reaction_10033953", "reaction_10078701", "reaction_10052030", "reaction_10045036", "reaction_10054601", "reaction_10043980", "reaction_10060207", "reaction_10085381", "reaction_10060252", "reaction_10033788", "reaction_10086033", "reaction_10078402", "reaction_10090015", "reaction_10090679", "reaction_10090681", "reaction_10064346", "reaction_10044784", "reaction_10033681", "reaction_10054611", "reaction_10078529", "reaction_10044776", "reaction_10043956", "reaction_10033755", "reaction_10043924", "reaction_10076261", "reaction_10060250", "reaction_10077864", "reaction_10043917", "reaction_10044851", "reaction_10077758", "reaction_10060264", "reaction_10033797", "reaction_10089850", "reaction_10042847", "reaction_10033962", "reaction_10060234", "reaction_10086371", "reaction_10033997", "reaction_10045029", "reaction_10076974", "reaction_10043933", "reaction_10033718", "reaction_10047022", "reaction_10060255", "reaction_10090162", "reaction_10041894", "reaction_10033737", "reaction_10043948", "reaction_10044794", "reaction_10044828", "reaction_10033824", "reaction_10033697", "reaction_10033728", "reaction_10077458", "reaction_10044837", "reaction_10033706", "reaction_10078366", "reaction_10090647", "reaction_10054585", "reaction_10076450", "reaction_10033840", "reaction_10052046", "reaction_10065455", "reaction_10087455", "reaction_10052027", "reaction_10033935", "reaction_10033833", "reaction_10044835", "reaction_10077124", "reaction_10078575", "reaction_10076360", "reaction_10057684", "reaction_10054620", "reaction_10043986", "reaction_10044801", "reaction_10044844", "reaction_10033969", "reaction_10090671", "reaction_10083204", "reaction_10057032", "reaction_10060361", "reaction_10057023", "reaction_10073477", "reaction_10033716", "reaction_10033757", "reaction_10060228", "reaction_10033979", "reaction_10033770", "reaction_10052040", "reaction_10052056", "reaction_10090155", "reaction_10089959", "reaction_10076441", "reaction_10033806", "reaction_10033944", "reaction_10033690", "reaction_10076406", "reaction_10078393", "reaction_10042838", "reaction_10047019", "reaction_10060218", "reaction_10051165", "reaction_10033988", "reaction_10077444", "reaction_10051198", "reaction_10077435", "reaction_10076130", "reaction_10090013", "reaction_10060231", "reaction_10077453" ] }, "R-BTA-2672351": { "id": "pathway_10094314", "reactome": "R-BTA-2672351", "name": "Stimuli-sensing channels", "reactions": [ "reaction_10091583", "reaction_10066232", "reaction_10067346", "reaction_10091542", "reaction_10066282", "reaction_10092050", "reaction_10066270", "reaction_10066227", "reaction_10066004", "reaction_10066199", "reaction_10066034", "reaction_10066021", "reaction_10084767", "reaction_10066289", "reaction_10067332", "reaction_10065965", "reaction_10066277", "reaction_10065991", "reaction_10066206" ] }, "R-BTA-5654227": { "id": "pathway_10094510", "reactome": "R-BTA-5654227", "name": "Phospholipase C-mediated cascade; FGFR3", "reactions": [ "reaction_10072946", "reaction_10072944", "reaction_10072913" ] }, "R-BTA-447043": { "id": "pathway_10093506", "reactome": "R-BTA-447043", "name": "Neurofascin interactions", "reactions": [ "reaction_10045224" ] }, "R-BTA-428930": { "id": "pathway_10093632", "reactome": "R-BTA-428930", "name": "Thromboxane signalling through TP receptor", "reactions": [ "reaction_10091701", "reaction_10049014", "reaction_10049035", "reaction_10047380" ] }, "R-BTA-421270": { "id": "pathway_10093688", "reactome": "R-BTA-421270", "name": "Cell-cell junction organization", "reactions": [ "reaction_10048352", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-418346": { "id": "pathway_10092852", "reactome": "R-BTA-418346", "name": "Platelet homeostasis", "reactions": [ "reaction_10049283", "reaction_10044018", "reaction_10048504", "reaction_10037607", "reaction_10047900", "reaction_10049290", "reaction_10048182", "reaction_10047893", "reaction_10047907", "reaction_10047930", "reaction_10049364", "reaction_10048635", "reaction_10044043", "reaction_10085323" ] }, "R-BTA-196741": { "id": "pathway_10092516", "reactome": "R-BTA-196741", "name": "Cobalamin (Cbl, vitamin B12) transport and metabolism", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10033889", "reaction_10066430", "reaction_10066585", "reaction_10066571", "reaction_10066526", "reaction_10066473", "reaction_10066461", "reaction_10066882", "reaction_10066444", "reaction_10066574", "reaction_10076254", "reaction_10066576", "reaction_10066458", "reaction_10066502", "reaction_10066587", "reaction_10066528", "reaction_10066569" ] }, "R-BTA-5620920": { "id": "pathway_10094490", "reactome": "R-BTA-5620920", "name": "Cargo trafficking to the periciliary membrane", "reactions": [ "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072489", "reaction_10072453", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-1296071": { "id": "pathway_10094028", "reactome": "R-BTA-1296071", "name": "Potassium Channels", "reactions": [ "reaction_10057418", "reaction_10057665", "reaction_10057399", "reaction_10057569", "reaction_10057616", "reaction_10057350", "reaction_10057682", "reaction_10057365", "reaction_10057656", "reaction_10057639", "reaction_10057588", "reaction_10057390", "reaction_10057607" ] }, "R-BTA-1236974": { "id": "pathway_10093998", "reactome": "R-BTA-1236974", "name": "ER-Phagosome pathway", "reactions": [ "reaction_10056982", "reaction_10084867", "reaction_10087823", "reaction_10084865" ] }, "R-BTA-195253": { "id": "pathway_10093270", "reactome": "R-BTA-195253", "name": "Degradation of beta-catenin by the destruction complex", "reactions": [ "reaction_10041647", "reaction_10063849", "reaction_10071356", "reaction_10041604", "reaction_10041629", "reaction_10041606", "reaction_10070931", "reaction_10041637", "reaction_10063843", "reaction_10069651", "reaction_10087597", "reaction_10041583", "reaction_10041640" ] }, "R-BTA-112307": { "id": "pathway_10093518", "reactome": "R-BTA-112307", "name": "Transmission across Electrical Synapses ", "reactions": [ "reaction_10045444", "reaction_10045455", "reaction_10045466" ] }, "R-BTA-9027307": { "id": "pathway_10094942", "reactome": "R-BTA-9027307", "name": "Biosynthesis of maresin-like SPMs", "reactions": [ "reaction_10090498" ] }, "R-BTA-2980766": { "id": "pathway_10094320", "reactome": "R-BTA-2980766", "name": "Nuclear Envelope Breakdown", "reactions": [ "reaction_10070705", "reaction_10069491", "reaction_10066345", "reaction_10066324" ] }, "R-BTA-8964043": { "id": "pathway_10094710", "reactome": "R-BTA-8964043", "name": "Plasma lipoprotein clearance", "reactions": [ "reaction_10086004", "reaction_10086002", "reaction_10084300", "reaction_10086026", "reaction_10086557", "reaction_10083113", "reaction_10085994" ] }, "R-BTA-211976": { "id": "pathway_10093240", "reactome": "R-BTA-211976", "name": "Endogenous sterols", "reactions": [ "reaction_10041193", "reaction_10041412", "reaction_10041386", "reaction_10041277", "reaction_10041397", "reaction_10041217", "reaction_10041206", "reaction_10044232", "reaction_10041415", "reaction_10077751", "reaction_10041177", "reaction_10041195", "reaction_10041500", "reaction_10041393" ] }, "R-BTA-5218921": { "id": "pathway_10094430", "reactome": "R-BTA-5218921", "name": "VEGFR2 mediated cell proliferation", "reactions": [ "reaction_10070615", "reaction_10070628", "reaction_10070657" ] }, "R-BTA-69052": { "id": "pathway_10092418", "reactome": "R-BTA-69052", "name": "Switching of origins to a post-replicative state", "reactions": [ "reaction_10033473" ] }, "R-BTA-75892": { "id": "pathway_10093422", "reactome": "R-BTA-75892", "name": "Platelet Adhesion to exposed collagen", "reactions": [ "reaction_10044020", "reaction_10049300" ] }, "R-BTA-212718": { "id": "pathway_10093446", "reactome": "R-BTA-212718", "name": "EGFR interacts with phospholipase C-gamma", "reactions": [ "reaction_10044465", "reaction_10044470", "reaction_10044472" ] }, "R-BTA-2029480": { "id": "pathway_10093300", "reactome": "R-BTA-2029480", "name": "Fcgamma receptor (FCGR) dependent phagocytosis", "reactions": [ "reaction_10061174", "reaction_10063353", "reaction_10063374", "reaction_10063368", "reaction_10041863" ] }, "R-BTA-390650": { "id": "pathway_10093616", "reactome": "R-BTA-390650", "name": "Histamine receptors", "reactions": [ "reaction_10091825", "reaction_10047234", "reaction_10047226" ] }, "R-BTA-1640170": { "id": "pathway_10092414", "reactome": "R-BTA-1640170", "name": "Cell Cycle", "reactions": [ "reaction_10051463", "reaction_10040542", "reaction_10084051", "reaction_10035745", "reaction_10065938", "reaction_10040576", "reaction_10040503", "reaction_10057808", "reaction_10039612", "reaction_10070705", "reaction_10091661", "reaction_10076341", "reaction_10065177", "reaction_10065201", "reaction_10091145", "reaction_10083565", "reaction_10040183", "reaction_10084102", "reaction_10065708", "reaction_10084047", "reaction_10087503", "reaction_10057812", "reaction_10087487", "reaction_10065095", "reaction_10038033", "reaction_10091685", "reaction_10038949", "reaction_10056602", "reaction_10064904", "reaction_10066487", "reaction_10069491", "reaction_10039614", "reaction_10056616", "reaction_10051465", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10057804", "reaction_10066489", "reaction_10040355", "reaction_10084096", "reaction_10091132", "reaction_10033512", "reaction_10065572", "reaction_10084090", "reaction_10091663", "reaction_10065563", "reaction_10040521", "reaction_10038947", "reaction_10051451", "reaction_10057821", "reaction_10064733", "reaction_10035747", "reaction_10078408", "reaction_10087385", "reaction_10084206", "reaction_10040059", "reaction_10065726", "reaction_10091634", "reaction_10033504", "reaction_10091658", "reaction_10033473", "reaction_10039801", "reaction_10033535", "reaction_10066345", "reaction_10084043", "reaction_10091656", "reaction_10033466", "reaction_10057816", "reaction_10051461", "reaction_10074695", "reaction_10091141", "reaction_10084028", "reaction_10065794", "reaction_10081470", "reaction_10087394", "reaction_10038035", "reaction_10083558", "reaction_10074692", "reaction_10038540", "reaction_10038534", "reaction_10066324" ] }, "R-BTA-442742": { "id": "pathway_10094950", "reactome": "R-BTA-442742", "name": "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling", "reactions": [ "reaction_10090547" ] }, "R-BTA-1247673": { "id": "pathway_10094010", "reactome": "R-BTA-1247673", "name": "Erythrocytes take up oxygen and release carbon dioxide", "reactions": [ "reaction_10057070", "reaction_10058792" ] }, "R-BTA-426117": { "id": "pathway_10093710", "reactome": "R-BTA-426117", "name": "Cation-coupled Chloride cotransporters", "reactions": [ "reaction_10048601", "reaction_10048594", "reaction_10048618" ] }, "R-BTA-3296197": { "id": "pathway_10093772", "reactome": "R-BTA-3296197", "name": "Hydroxycarboxylic acid-binding receptors", "reactions": [ "reaction_10067364", "reaction_10067362", "reaction_10049659" ] }, "R-BTA-1655829": { "id": "pathway_10094140", "reactome": "R-BTA-1655829", "name": "Regulation of cholesterol biosynthesis by SREBP (SREBF)", "reactions": [ "reaction_10063562", "reaction_10063560", "reaction_10063564", "reaction_10060346" ] }, "R-BTA-9033500": { "id": "pathway_10094956", "reactome": "R-BTA-9033500", "name": "TYSND1 cleaves peroxisomal proteins", "reactions": [ "reaction_10090604" ] }, "R-BTA-6785807": { "id": "pathway_10094642", "reactome": "R-BTA-6785807", "name": "Interleukin-4 and Interleukin-13 signaling", "reactions": [ "reaction_10077633", "reaction_10077870", "reaction_10077945", "reaction_10091731", "reaction_10077723", "reaction_10077764", "reaction_10077874" ] }, "R-BTA-450282": { "id": "pathway_10093058", "reactome": "R-BTA-450282", "name": "MAPK targets/ Nuclear events mediated by MAP kinases", "reactions": [ "reaction_10050208", "reaction_10041950", "reaction_10039508", "reaction_10043488", "reaction_10042826" ] }, "R-BTA-442660": { "id": "pathway_10093478", "reactome": "R-BTA-442660", "name": "Na+/Cl- dependent neurotransmitter transporters", "reactions": [ "reaction_10045480", "reaction_10049599", "reaction_10044934", "reaction_10045419", "reaction_10044941", "reaction_10049583", "reaction_10045487", "reaction_10049613", "reaction_10044948", "reaction_10049592" ] }, "R-BTA-9006335": { "id": "pathway_10094886", "reactome": "R-BTA-9006335", "name": "Signaling by Erythropoietin", "reactions": [ "reaction_10090501", "reaction_10090428", "reaction_10089841" ] }, "R-BTA-8963684": { "id": "pathway_10092540", "reactome": "R-BTA-8963684", "name": "Tyrosine catabolism", "reactions": [ "reaction_10033962", "reaction_10033953", "reaction_10033944" ] }, "R-BTA-70268": { "id": "pathway_10092478", "reactome": "R-BTA-70268", "name": "Pyruvate metabolism", "reactions": [ "reaction_10089721", "reaction_10034240", "reaction_10076468", "reaction_10089728", "reaction_10033671" ] }, "R-BTA-418597": { "id": "pathway_10093638", "reactome": "R-BTA-418597", "name": "G alpha (z) signalling events", "reactions": [ "reaction_10089217", "reaction_10089207", "reaction_10047468", "reaction_10089167", "reaction_10051656" ] }, "R-BTA-111464": { "id": "pathway_10092834", "reactome": "R-BTA-111464", "name": "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ", "reactions": [ "reaction_10037293" ] }, "R-BTA-72662": { "id": "pathway_10092574", "reactome": "R-BTA-72662", "name": "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S", "reactions": [ "reaction_10034365" ] }, "R-BTA-9027604": { "id": "pathway_10094946", "reactome": "R-BTA-9027604", "name": "Biosynthesis of electrophilic \u03c9-3 PUFA oxo-derivatives", "reactions": [ "reaction_10090504", "reaction_10090506", "reaction_10090508", "reaction_10090510" ] }, "R-BTA-5693607": { "id": "pathway_10094588", "reactome": "R-BTA-5693607", "name": "Processing of DNA double-strand break ends", "reactions": [ "reaction_10074798", "reaction_10076339", "reaction_10075037" ] }, "R-BTA-1483257": { "id": "pathway_10092670", "reactome": "R-BTA-1483257", "name": "Phospholipid metabolism", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10082931", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10060614", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10060569", "reaction_10035786", "reaction_10082934", "reaction_10058913", "reaction_10060597", "reaction_10085808", "reaction_10060600", "reaction_10058998", "reaction_10085798", "reaction_10060590", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10060579", "reaction_10084526", "reaction_10071344", "reaction_10060448", "reaction_10060429", "reaction_10083369", "reaction_10083211", "reaction_10059035", "reaction_10082155", "reaction_10058996", "reaction_10058970", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10060572", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10060518", "reaction_10058834", "reaction_10085340", "reaction_10082152", "reaction_10058874", "reaction_10085784", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10060588", "reaction_10060476", "reaction_10085843", "reaction_10060498", "reaction_10059073", "reaction_10060535", "reaction_10059114", "reaction_10060537", "reaction_10058892", "reaction_10082147", "reaction_10060516", "reaction_10059014", "reaction_10082136", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10060468", "reaction_10085780", "reaction_10085024", "reaction_10058899", "reaction_10060501", "reaction_10060553", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10083092", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10083800", "reaction_10060556", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10085775", "reaction_10086064", "reaction_10058980", "reaction_10060550", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058841", "reaction_10059026", "reaction_10060483", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10060595", "reaction_10059101", "reaction_10060574", "reaction_10058948", "reaction_10058985", "reaction_10060558", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10060461", "reaction_10076824" ] }, "R-BTA-156584": { "id": "pathway_10092914", "reactome": "R-BTA-156584", "name": "Cytosolic sulfonation of small molecules", "reactions": [ "reaction_10040147", "reaction_10039887", "reaction_10038318", "reaction_10038231", "reaction_10040136", "reaction_10040129", "reaction_10039890", "reaction_10048727", "reaction_10040131", "reaction_10040122", "reaction_10040157", "reaction_10040112", "reaction_10040115", "reaction_10076799", "reaction_10040120", "reaction_10038340", "reaction_10038320", "reaction_10040107", "reaction_10040152", "reaction_10040098", "reaction_10051570", "reaction_10088617", "reaction_10040117", "reaction_10088580" ] }, "R-BTA-450408": { "id": "pathway_10093808", "reactome": "R-BTA-450408", "name": "AUF1 (hnRNP D0) binds and destabilizes mRNA", "reactions": [ "reaction_10050342" ] }, "R-BTA-9648002": { "id": "pathway_10095012", "reactome": "R-BTA-9648002", "name": "RAS processing", "reactions": [ "reaction_10091490", "reaction_10091458", "reaction_10091506", "reaction_10091527", "reaction_10091515", "reaction_10091479" ] }, "R-BTA-5654688": { "id": "pathway_10094536", "reactome": "R-BTA-5654688", "name": "SHC-mediated cascade:FGFR1", "reactions": [ "reaction_10073119", "reaction_10073102", "reaction_10073122", "reaction_10073087" ] }, "R-BTA-211916": { "id": "pathway_10093416", "reactome": "R-BTA-211916", "name": "Vitamins", "reactions": [ "reaction_10044225", "reaction_10044211", "reaction_10044293", "reaction_10043971", "reaction_10043964" ] }, "R-BTA-6811555": { "id": "pathway_10094694", "reactome": "R-BTA-6811555", "name": "PI5P Regulates TP53 Acetylation", "reactions": [ "reaction_10082931", "reaction_10083092", "reaction_10086155", "reaction_10083077", "reaction_10083072", "reaction_10082923", "reaction_10082934" ] }, "R-BTA-5173214": { "id": "pathway_10094416", "reactome": "R-BTA-5173214", "name": "O-glycosylation of TSR domain-containing proteins", "reactions": [ "reaction_10070145" ] }, "R-BTA-2142789": { "id": "pathway_10094254", "reactome": "R-BTA-2142789", "name": "Ubiquinol biosynthesis", "reactions": [ "reaction_10064591" ] }, "R-BTA-1614603": { "id": "pathway_10094130", "reactome": "R-BTA-1614603", "name": "Cysteine formation from homocysteine", "reactions": [ "reaction_10060231", "reaction_10060207" ] }, "R-BTA-389356": { "id": "pathway_10093568", "reactome": "R-BTA-389356", "name": "CD28 co-stimulation", "reactions": [ "reaction_10046907", "reaction_10046943", "reaction_10047530", "reaction_10065227", "reaction_10046932", "reaction_10046951", "reaction_10046822", "reaction_10046811", "reaction_10046787" ] }, "R-BTA-9609507": { "id": "pathway_10094876", "reactome": "R-BTA-9609507", "name": "Protein localization", "reactions": [ "reaction_10090604", "reaction_10089391", "reaction_10090770", "reaction_10090593" ] }, "R-BTA-9675108": { "id": "pathway_10093386", "reactome": "R-BTA-9675108", "name": "Nervous system development", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10091009", "reaction_10084393", "reaction_10084185", "reaction_10091007", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-163210": { "id": "pathway_10092994", "reactome": "R-BTA-163210", "name": "Formation of ATP by chemiosmotic coupling", "reactions": [ "reaction_10039049", "reaction_10039044", "reaction_10039047" ] }, "R-BTA-112314": { "id": "pathway_10092800", "reactome": "R-BTA-112314", "name": "Neurotransmitter receptors and postsynaptic signal transmission", "reactions": [ "reaction_10051085", "reaction_10039653", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10050517", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10054318", "reaction_10054372", "reaction_10036981", "reaction_10051498", "reaction_10090547", "reaction_10051525", "reaction_10049478", "reaction_10051523", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10039664" ] }, "R-BTA-77108": { "id": "pathway_10092612", "reactome": "R-BTA-77108", "name": "Utilization of Ketone Bodies", "reactions": [ "reaction_10035374", "reaction_10035415", "reaction_10035417" ] }, "R-BTA-69278": { "id": "pathway_10092412", "reactome": "R-BTA-69278", "name": "Cell Cycle, Mitotic", "reactions": [ "reaction_10057804", "reaction_10084102", "reaction_10039801", "reaction_10066489", "reaction_10065708", "reaction_10084047", "reaction_10040542", "reaction_10066345", "reaction_10040355", "reaction_10084096", "reaction_10087503", "reaction_10091132", "reaction_10084043", "reaction_10084051", "reaction_10035745", "reaction_10033512", "reaction_10065938", "reaction_10057812", "reaction_10065572", "reaction_10091656", "reaction_10087487", "reaction_10084090", "reaction_10033466", "reaction_10065095", "reaction_10057816", "reaction_10040576", "reaction_10040503", "reaction_10038033", "reaction_10065563", "reaction_10091141", "reaction_10084028", "reaction_10057808", "reaction_10039612", "reaction_10056602", "reaction_10070705", "reaction_10065794", "reaction_10033473", "reaction_10040521", "reaction_10087394", "reaction_10091661", "reaction_10057821", "reaction_10038035", "reaction_10064733", "reaction_10083558", "reaction_10087385", "reaction_10084206", "reaction_10065177", "reaction_10064904", "reaction_10066487", "reaction_10065201", "reaction_10069491", "reaction_10035747", "reaction_10065726", "reaction_10039614", "reaction_10091145", "reaction_10056616", "reaction_10091634", "reaction_10033504", "reaction_10083565", "reaction_10040183", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10091658", "reaction_10066324" ] }, "R-BTA-5654221": { "id": "pathway_10094506", "reactome": "R-BTA-5654221", "name": "Phospholipase C-mediated cascade; FGFR2", "reactions": [ "reaction_10072931", "reaction_10072909", "reaction_10072929" ] }, "R-BTA-181438": { "id": "pathway_10093042", "reactome": "R-BTA-181438", "name": "Toll Like Receptor 2 (TLR2) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-6814122": { "id": "pathway_10094716", "reactome": "R-BTA-6814122", "name": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-141430": { "id": "pathway_10092902", "reactome": "R-BTA-141430", "name": "Inactivation of APC/C via direct inhibition of the APC/C complex", "reactions": [ "reaction_10038035" ] }, "R-BTA-112040": { "id": "pathway_10092772", "reactome": "R-BTA-112040", "name": "G-protein mediated events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10039653", "reaction_10036981", "reaction_10039671", "reaction_10037045", "reaction_10039674", "reaction_10049478", "reaction_10039676", "reaction_10036959", "reaction_10039651", "reaction_10037024", "reaction_10039667", "reaction_10039658", "reaction_10039664" ] }, "R-BTA-2514856": { "id": "pathway_10092626", "reactome": "R-BTA-2514856", "name": "The phototransduction cascade", "reactions": [ "reaction_10035596", "reaction_10065944", "reaction_10065808", "reaction_10035406", "reaction_10035619", "reaction_10077744", "reaction_10065940" ] }, "R-BTA-193648": { "id": "pathway_10093256", "reactome": "R-BTA-193648", "name": "NRAGE signals death through JNK", "reactions": [ "reaction_10043753", "reaction_10041333" ] }, "R-BTA-844456": { "id": "pathway_10093864", "reactome": "R-BTA-844456", "name": "The NLRP3 inflammasome", "reactions": [ "reaction_10051836" ] }, "R-BTA-6806664": { "id": "pathway_10092948", "reactome": "R-BTA-6806664", "name": "Metabolism of vitamin K", "reactions": [ "reaction_10081935", "reaction_10081928", "reaction_10090493", "reaction_10038427" ] }, "R-BTA-6794361": { "id": "pathway_10094660", "reactome": "R-BTA-6794361", "name": "Neurexins and neuroligins", "reactions": [ "reaction_10078522", "reaction_10078488", "reaction_10078446", "reaction_10078518", "reaction_10078600", "reaction_10078464", "reaction_10078466" ] }, "R-BTA-204998": { "id": "pathway_10093258", "reactome": "R-BTA-204998", "name": "Cell death signalling via NRAGE, NRIF and NADE", "reactions": [ "reaction_10043744", "reaction_10043753", "reaction_10043778", "reaction_10043739", "reaction_10041333" ] }, "R-BTA-381676": { "id": "pathway_10093552", "reactome": "R-BTA-381676", "name": "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion", "reactions": [ "reaction_10046630", "reaction_10046642", "reaction_10046623", "reaction_10046648" ] }, "R-BTA-75157": { "id": "pathway_10092530", "reactome": "R-BTA-75157", "name": "FasL/ CD95L signaling", "reactions": [ "reaction_10036148", "reaction_10036146", "reaction_10033926", "reaction_10035726" ] }, "R-BTA-727802": { "id": "pathway_10093118", "reactome": "R-BTA-727802", "name": "Transport of nucleotide sugars", "reactions": [ "reaction_10051577", "reaction_10039874", "reaction_10051570", "reaction_10051580", "reaction_10051554", "reaction_10051587", "reaction_10051589" ] }, "R-BTA-379726": { "id": "pathway_10093796", "reactome": "R-BTA-379726", "name": "Mitochondrial tRNA aminoacylation", "reactions": [ "reaction_10050169" ] }, "R-BTA-199418": { "id": "pathway_10094148", "reactome": "R-BTA-199418", "name": "Negative regulation of the PI3K/AKT network", "reactions": [ "reaction_10060556", "reaction_10060448" ] }, "R-BTA-6811442": { "id": "pathway_10094704", "reactome": "R-BTA-6811442", "name": "Intra-Golgi and retrograde Golgi-to-ER traffic", "reactions": [ "reaction_10083458", "reaction_10083425", "reaction_10083340", "reaction_10083342", "reaction_10083006", "reaction_10082999", "reaction_10083767", "reaction_10083712", "reaction_10083451", "reaction_10083143", "reaction_10083004", "reaction_10083179", "reaction_10083187", "reaction_10083149", "reaction_10083056" ] }, "R-BTA-3769402": { "id": "pathway_10094350", "reactome": "R-BTA-3769402", "name": "Deactivation of the beta-catenin transactivating complex", "reactions": [ "reaction_10067694", "reaction_10067696", "reaction_10067698" ] }, "R-BTA-8957322": { "id": "pathway_10092930", "reactome": "R-BTA-8957322", "name": "Metabolism of steroids", "reactions": [ "reaction_10041308", "reaction_10041363", "reaction_10041297", "reaction_10041104", "reaction_10050650", "reaction_10077113", "reaction_10041359", "reaction_10081990", "reaction_10041323", "reaction_10041284", "reaction_10041186", "reaction_10084679", "reaction_10041321", "reaction_10041437", "reaction_10041671", "reaction_10041684", "reaction_10063560", "reaction_10041277", "reaction_10041319", "reaction_10041179", "reaction_10041477", "reaction_10076281", "reaction_10041500", "reaction_10041337", "reaction_10041377", "reaction_10044739", "reaction_10041721", "reaction_10041172", "reaction_10040904", "reaction_10041486", "reaction_10043885", "reaction_10041177", "reaction_10040913", "reaction_10043971", "reaction_10041386", "reaction_10041357", "reaction_10040881", "reaction_10041226", "reaction_10041347", "reaction_10041341", "reaction_10041415", "reaction_10081988", "reaction_10041310", "reaction_10041325", "reaction_10081986", "reaction_10041111", "reaction_10041170", "reaction_10041290", "reaction_10040895", "reaction_10041327", "reaction_10060346", "reaction_10041193", "reaction_10041206", "reaction_10083496", "reaction_10041664", "reaction_10041373", "reaction_10041293", "reaction_10043903", "reaction_10043910", "reaction_10041716", "reaction_10088928", "reaction_10085316", "reaction_10041412", "reaction_10063562", "reaction_10063564", "reaction_10041692", "reaction_10041484", "reaction_10041349", "reaction_10041379", "reaction_10092062", "reaction_10038347", "reaction_10041397", "reaction_10041493", "reaction_10041210", "reaction_10044741", "reaction_10041393", "reaction_10041345", "reaction_10041204", "reaction_10041367", "reaction_10040924", "reaction_10041339", "reaction_10041097", "reaction_10041301", "reaction_10041502", "reaction_10041299", "reaction_10041195", "reaction_10088926", "reaction_10041369", "reaction_10085806", "reaction_10041197", "reaction_10041343", "reaction_10041208", "reaction_10085291", "reaction_10041355", "reaction_10041365", "reaction_10040933", "reaction_10041424", "reaction_10041728", "reaction_10040892", "reaction_10092065", "reaction_10041351", "reaction_10041719", "reaction_10041371", "reaction_10041375", "reaction_10041269", "reaction_10041295", "reaction_10057880", "reaction_10041395", "reaction_10088019", "reaction_10041335", "reaction_10043964", "reaction_10041353", "reaction_10043984", "reaction_10041317", "reaction_10041361", "reaction_10041217", "reaction_10040922", "reaction_10051676" ] }, "R-BTA-379724": { "id": "pathway_10092568", "reactome": "R-BTA-379724", "name": "tRNA Aminoacylation", "reactions": [ "reaction_10050169", "reaction_10034224" ] }, "R-BTA-1971475": { "id": "pathway_10094180", "reactome": "R-BTA-1971475", "name": "A tetrasaccharide linker sequence is required for GAG synthesis", "reactions": [ "reaction_10061395", "reaction_10061402", "reaction_10061350", "reaction_10061251", "reaction_10091286" ] }, "R-BTA-9639288": { "id": "pathway_10095008", "reactome": "R-BTA-9639288", "name": "Amino acids regulate mTORC1", "reactions": [ "reaction_10091354", "reaction_10091356", "reaction_10091336", "reaction_10091365", "reaction_10091351", "reaction_10091401", "reaction_10091404" ] }, "R-BTA-191650": { "id": "pathway_10093228", "reactome": "R-BTA-191650", "name": "Regulation of gap junction activity", "reactions": [ "reaction_10040967", "reaction_10040955", "reaction_10040961" ] }, "R-BTA-1834941": { "id": "pathway_10094212", "reactome": "R-BTA-1834941", "name": "STING mediated induction of host immune responses", "reactions": [ "reaction_10065388", "reaction_10063376", "reaction_10065413", "reaction_10065407", "reaction_10090019", "reaction_10067233", "reaction_10067223", "reaction_10067216", "reaction_10066880", "reaction_10067231", "reaction_10067229", "reaction_10066532", "reaction_10067225", "reaction_10065402" ] }, "R-BTA-163200": { "id": "pathway_10092970", "reactome": "R-BTA-163200", "name": "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.", "reactions": [ "reaction_10080521", "reaction_10039044", "reaction_10080519", "reaction_10080517", "reaction_10039049", "reaction_10038895", "reaction_10039047", "reaction_10039604", "reaction_10039254", "reaction_10080515", "reaction_10039242", "reaction_10038647", "reaction_10039240" ] }, "R-BTA-2142753": { "id": "pathway_10092870", "reactome": "R-BTA-2142753", "name": "Arachidonic acid metabolism", "reactions": [ "reaction_10064516", "reaction_10065225", "reaction_10064546", "reaction_10064521", "reaction_10065216", "reaction_10037751", "reaction_10065210", "reaction_10064565", "reaction_10064554", "reaction_10065223", "reaction_10064465", "reaction_10064581", "reaction_10044599", "reaction_10086336", "reaction_10064503", "reaction_10064474", "reaction_10037748", "reaction_10064534", "reaction_10077001", "reaction_10065213", "reaction_10064531", "reaction_10064567", "reaction_10064578", "reaction_10064482", "reaction_10064506", "reaction_10064526", "reaction_10064452", "reaction_10044657", "reaction_10064511", "reaction_10044151", "reaction_10076382", "reaction_10064442", "reaction_10064479", "reaction_10064445" ] }, "R-BTA-2465910": { "id": "pathway_10094256", "reactome": "R-BTA-2465910", "name": "MASTL Facilitates Mitotic Progression", "reactions": [ "reaction_10064733", "reaction_10065572" ] }, "R-BTA-449836": { "id": "pathway_10093788", "reactome": "R-BTA-449836", "name": "Other interleukin signaling", "reactions": [ "reaction_10089689", "reaction_10089691", "reaction_10090027", "reaction_10090031", "reaction_10049983", "reaction_10077843" ] }, "R-BTA-77352": { "id": "pathway_10092710", "reactome": "R-BTA-77352", "name": "Beta oxidation of butanoyl-CoA to acetyl-CoA", "reactions": [ "reaction_10036025" ] }, "R-BTA-4420097": { "id": "pathway_10093156", "reactome": "R-BTA-4420097", "name": "VEGFA-VEGFR2 Pathway", "reactions": [ "reaction_10070615", "reaction_10070589", "reaction_10070628", "reaction_10070657", "reaction_10070676", "reaction_10070596", "reaction_10071506", "reaction_10070624", "reaction_10065227", "reaction_10040570", "reaction_10071504", "reaction_10069535", "reaction_10071508", "reaction_10070651", "reaction_10070645", "reaction_10070594" ] }, "R-BTA-264876": { "id": "pathway_10093764", "reactome": "R-BTA-264876", "name": "Insulin processing", "reactions": [ "reaction_10049385", "reaction_10049392" ] }, "R-BTA-5620916": { "id": "pathway_10094488", "reactome": "R-BTA-5620916", "name": "VxPx cargo-targeting to cilium", "reactions": [ "reaction_10072326", "reaction_10072426", "reaction_10072401" ] }, "R-BTA-391251": { "id": "pathway_10094720", "reactome": "R-BTA-391251", "name": "Protein folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-5696399": { "id": "pathway_10092744", "reactome": "R-BTA-5696399", "name": "Global Genome Nucleotide Excision Repair (GG-NER)", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10077016", "reaction_10076071", "reaction_10076009", "reaction_10036661" ] }, "R-BTA-5654689": { "id": "pathway_10094538", "reactome": "R-BTA-5654689", "name": "PI-3K cascade:FGFR1", "reactions": [ "reaction_10073115", "reaction_10073228", "reaction_10073225" ] }, "R-BTA-76002": { "id": "pathway_10092840", "reactome": "R-BTA-76002", "name": "Platelet activation, signaling and aggregation", "reactions": [ "reaction_10050630", "reaction_10092299", "reaction_10048580", "reaction_10048543", "reaction_10050870", "reaction_10051002", "reaction_10047475", "reaction_10049014", "reaction_10053213", "reaction_10050948", "reaction_10037580", "reaction_10048587", "reaction_10049279", "reaction_10049035", "reaction_10049426", "reaction_10037517", "reaction_10050994", "reaction_10049395", "reaction_10047870", "reaction_10065227", "reaction_10037557", "reaction_10047880", "reaction_10076743", "reaction_10047380", "reaction_10045016", "reaction_10037353", "reaction_10049039", "reaction_10047212", "reaction_10051062", "reaction_10049071", "reaction_10047985", "reaction_10047886", "reaction_10091701", "reaction_10049506", "reaction_10037433", "reaction_10048632", "reaction_10037588", "reaction_10048660", "reaction_10047857", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-69190": { "id": "pathway_10092428", "reactome": "R-BTA-69190", "name": "DNA strand elongation", "reactions": [ "reaction_10033504", "reaction_10040183" ] }, "R-BTA-109703": { "id": "pathway_10092954", "reactome": "R-BTA-109703", "name": "PKB-mediated events", "reactions": [ "reaction_10038450" ] }, "R-BTA-388841": { "id": "pathway_10093570", "reactome": "R-BTA-388841", "name": "Costimulation by the CD28 family", "reactions": [ "reaction_10046907", "reaction_10046943", "reaction_10046834", "reaction_10046909", "reaction_10046903", "reaction_10047530", "reaction_10046959", "reaction_10065227", "reaction_10046932", "reaction_10046807", "reaction_10091743", "reaction_10046951", "reaction_10046822", "reaction_10046811", "reaction_10046787", "reaction_10046888" ] }, "R-BTA-674695": { "id": "pathway_10092810", "reactome": "R-BTA-674695", "name": "RNA Polymerase II Pre-transcription Events", "reactions": [ "reaction_10037189", "reaction_10037187", "reaction_10037185", "reaction_10037207", "reaction_10037201" ] }, "R-BTA-9034015": { "id": "pathway_10094964", "reactome": "R-BTA-9034015", "name": "Signaling by NTRK3 (TRKC)", "reactions": [ "reaction_10090666", "reaction_10090675", "reaction_10090727", "reaction_10090722" ] }, "R-BTA-3371453": { "id": "pathway_10094360", "reactome": "R-BTA-3371453", "name": "Regulation of HSF1-mediated heat shock response", "reactions": [ "reaction_10071208", "reaction_10071127", "reaction_10068008", "reaction_10067993", "reaction_10071313", "reaction_10071241" ] }, "R-BTA-174362": { "id": "pathway_10093120", "reactome": "R-BTA-174362", "name": "Transport and synthesis of PAPS", "reactions": [ "reaction_10039890", "reaction_10039887", "reaction_10048727", "reaction_10051570" ] }, "R-BTA-429593": { "id": "pathway_10093734", "reactome": "R-BTA-429593", "name": "Inositol transporters", "reactions": [ "reaction_10049060", "reaction_10049078" ] }, "R-BTA-8849469": { "id": "pathway_10094738", "reactome": "R-BTA-8849469", "name": "PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1", "reactions": [ "reaction_10083646", "reaction_10083638", "reaction_10083632", "reaction_10083652" ] }, "R-BTA-77285": { "id": "pathway_10092708", "reactome": "R-BTA-77285", "name": "Beta oxidation of myristoyl-CoA to lauroyl-CoA", "reactions": [ "reaction_10036023" ] }, "R-BTA-6785631": { "id": "pathway_10094640", "reactome": "R-BTA-6785631", "name": "ERBB2 Regulates Cell Motility", "reactions": [ "reaction_10077605", "reaction_10077601" ] }, "R-BTA-1428517": { "id": "pathway_10092482", "reactome": "R-BTA-1428517", "name": "The citric acid (TCA) cycle and respiratory electron transport", "reactions": [ "reaction_10080521", "reaction_10039044", "reaction_10051980", "reaction_10038895", "reaction_10051973", "reaction_10089795", "reaction_10089782", "reaction_10080517", "reaction_10089721", "reaction_10039047", "reaction_10089808", "reaction_10080519", "reaction_10039254", "reaction_10039049", "reaction_10039604", "reaction_10080515", "reaction_10050437", "reaction_10076468", "reaction_10039240", "reaction_10034240", "reaction_10050446", "reaction_10089728", "reaction_10039242", "reaction_10038647", "reaction_10033868", "reaction_10033671" ] }, "R-BTA-1482801": { "id": "pathway_10094102", "reactome": "R-BTA-1482801", "name": "Acyl chain remodelling of PS", "reactions": [ "reaction_10058943", "reaction_10058880", "reaction_10059014", "reaction_10058945", "reaction_10059849", "reaction_10085310", "reaction_10058916" ] }, "R-BTA-1912420": { "id": "pathway_10094182", "reactome": "R-BTA-1912420", "name": "Pre-NOTCH Processing in Golgi", "reactions": [ "reaction_10061449" ] }, "R-BTA-189200": { "id": "pathway_10093732", "reactome": "R-BTA-189200", "name": "Cellular hexose transport", "reactions": [ "reaction_10089038", "reaction_10089029", "reaction_10085907", "reaction_10049053", "reaction_10089024", "reaction_10049046" ] }, "R-BTA-159854": { "id": "pathway_10092942", "reactome": "R-BTA-159854", "name": "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins", "reactions": [ "reaction_10038438", "reaction_10038408", "reaction_10038416" ] }, "R-BTA-111457": { "id": "pathway_10092820", "reactome": "R-BTA-111457", "name": "Release of apoptotic factors from the mitochondria", "reactions": [ "reaction_10081897", "reaction_10037253", "reaction_10037264", "reaction_10091186" ] }, "R-BTA-376176": { "id": "pathway_10093382", "reactome": "R-BTA-376176", "name": "Signaling by ROBO receptors", "reactions": [ "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10048935", "reaction_10089713", "reaction_10090179", "reaction_10048951", "reaction_10043671" ] }, "R-BTA-196108": { "id": "pathway_10093280", "reactome": "R-BTA-196108", "name": "Pregnenolone biosynthesis", "reactions": [ "reaction_10041716", "reaction_10041684", "reaction_10041692" ] }, "R-BTA-445717": { "id": "pathway_10093644", "reactome": "R-BTA-445717", "name": "Aquaporin-mediated transport", "reactions": [ "reaction_10049243", "reaction_10047483", "reaction_10049271", "reaction_10049253", "reaction_10051148", "reaction_10051145", "reaction_10049241", "reaction_10051150", "reaction_10051143", "reaction_10049262", "reaction_10051141", "reaction_10051136" ] }, "R-BTA-909733": { "id": "pathway_10093880", "reactome": "R-BTA-909733", "name": "Interferon alpha/beta signaling", "reactions": [ "reaction_10052229", "reaction_10052217", "reaction_10055955", "reaction_10055958", "reaction_10052189", "reaction_10052213", "reaction_10052196", "reaction_10052236", "reaction_10052159", "reaction_10055946", "reaction_10052210", "reaction_10070719", "reaction_10052147", "reaction_10052347", "reaction_10091725", "reaction_10052233" ] }, "R-BTA-392023": { "id": "pathway_10093612", "reactome": "R-BTA-392023", "name": "Adrenaline signalling through Alpha-2 adrenergic receptor", "reactions": [ "reaction_10047212" ] }, "R-BTA-3214842": { "id": "pathway_10094330", "reactome": "R-BTA-3214842", "name": "HDMs demethylate histones", "reactions": [ "reaction_10073380", "reaction_10069719", "reaction_10073402", "reaction_10069754", "reaction_10073396", "reaction_10073382", "reaction_10069796", "reaction_10073406", "reaction_10073400", "reaction_10069769", "reaction_10073384", "reaction_10069747", "reaction_10073394", "reaction_10073404", "reaction_10066651", "reaction_10069740" ] }, "R-BTA-442755": { "id": "pathway_10092798", "reactome": "R-BTA-442755", "name": "Activation of NMDA receptors and postsynaptic events", "reactions": [ "reaction_10090547", "reaction_10091067", "reaction_10049478", "reaction_10091075", "reaction_10036981" ] }, "R-BTA-194441": { "id": "pathway_10093232", "reactome": "R-BTA-194441", "name": "Metabolism of non-coding RNA", "reactions": [ "reaction_10041050", "reaction_10041039" ] }, "R-BTA-156588": { "id": "pathway_10092924", "reactome": "R-BTA-156588", "name": "Glucuronidation", "reactions": [ "reaction_10039874", "reaction_10038338", "reaction_10038336", "reaction_10039749", "reaction_10039916", "reaction_10076785" ] }, "R-BTA-114604": { "id": "pathway_10092844", "reactome": "R-BTA-114604", "name": "GPVI-mediated activation cascade", "reactions": [ "reaction_10050630", "reaction_10049426", "reaction_10037517", "reaction_10049395", "reaction_10049071", "reaction_10065227", "reaction_10037557", "reaction_10037588" ] }, "R-BTA-1169410": { "id": "pathway_10093972", "reactome": "R-BTA-1169410", "name": "Antiviral mechanism by IFN-stimulated genes", "reactions": [ "reaction_10089703", "reaction_10060730", "reaction_10060732", "reaction_10056315", "reaction_10089341", "reaction_10089696", "reaction_10056289", "reaction_10056283", "reaction_10060694", "reaction_10056287", "reaction_10089349", "reaction_10056297" ] }, "R-BTA-372790": { "id": "pathway_10092780", "reactome": "R-BTA-372790", "name": "Signaling by GPCR", "reactions": [ "reaction_10037037", "reaction_10081580", "reaction_10047236", "reaction_10089211", "reaction_10089207", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10037045", "reaction_10039676", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10047979", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10089224", "reaction_10048587", "reaction_10047334", "reaction_10046149", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10076743", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10037549", "reaction_10037022", "reaction_10083878", "reaction_10048370", "reaction_10047214", "reaction_10083880", "reaction_10039485", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10088942", "reaction_10084702", "reaction_10088940", "reaction_10089228", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10047498", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10064919", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10047823", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10064910", "reaction_10041950", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10046534", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10051656", "reaction_10046731", "reaction_10084016", "reaction_10083951", "reaction_10089222", "reaction_10045292", "reaction_10047947", "reaction_10049659", "reaction_10039671", "reaction_10047366", "reaction_10039674", "reaction_10091763", "reaction_10046729", "reaction_10037330", "reaction_10048304", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10089217", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10037004", "reaction_10049478", "reaction_10048632", "reaction_10051667", "reaction_10048660", "reaction_10039664", "reaction_10049645", "reaction_10049615", "reaction_10043315", "reaction_10046917", "reaction_10047866", "reaction_10039653", "reaction_10047468", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10039667", "reaction_10049643", "reaction_10037332", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10047552", "reaction_10048178", "reaction_10089203", "reaction_10049657", "reaction_10048180", "reaction_10036959", "reaction_10086565", "reaction_10039658", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047956", "reaction_10047380", "reaction_10049681", "reaction_10089197", "reaction_10089214", "reaction_10067358", "reaction_10048170", "reaction_10036981", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10092055", "reaction_10039651", "reaction_10091247", "reaction_10045106" ] }, "R-BTA-209822": { "id": "pathway_10093528", "reactome": "R-BTA-209822", "name": "Glycoprotein hormones", "reactions": [ "reaction_10045696", "reaction_10045736", "reaction_10045744", "reaction_10045694" ] }, "R-BTA-70326": { "id": "pathway_10092474", "reactome": "R-BTA-70326", "name": "Glucose metabolism", "reactions": [ "reaction_10067247", "reaction_10033620", "reaction_10033757", "reaction_10080765", "reaction_10045692", "reaction_10033611", "reaction_10078710", "reaction_10033629", "reaction_10088737", "reaction_10034071", "reaction_10076815", "reaction_10067254", "reaction_10045043", "reaction_10067240", "reaction_10034157", "reaction_10033638", "reaction_10045029", "reaction_10045050", "reaction_10034238", "reaction_10041885", "reaction_10041878", "reaction_10034140", "reaction_10033718" ] }, "R-BTA-189451": { "id": "pathway_10093168", "reactome": "R-BTA-189451", "name": "Heme biosynthesis", "reactions": [ "reaction_10040682", "reaction_10040688", "reaction_10040645", "reaction_10040663", "reaction_10040672", "reaction_10040654", "reaction_10066416" ] }, "R-BTA-190375": { "id": "pathway_10093180", "reactome": "R-BTA-190375", "name": "FGFR2c ligand binding and activation", "reactions": [ "reaction_10040788", "reaction_10040720" ] }, "R-BTA-177128": { "id": "pathway_10092938", "reactome": "R-BTA-177128", "name": "Conjugation of salicylate with glycine", "reactions": [ "reaction_10038380", "reaction_10038382" ] }, "R-BTA-4641263": { "id": "pathway_10094406", "reactome": "R-BTA-4641263", "name": "Regulation of FZD by ubiquitination", "reactions": [ "reaction_10069664", "reaction_10069647", "reaction_10069645" ] }, "R-BTA-8850843": { "id": "pathway_10094748", "reactome": "R-BTA-8850843", "name": "Phosphate bond hydrolysis by NTPDase proteins", "reactions": [ "reaction_10083889", "reaction_10083864", "reaction_10083876", "reaction_10083852", "reaction_10083926", "reaction_10083873", "reaction_10083861" ] }, "R-BTA-9634635": { "id": "pathway_10095006", "reactome": "R-BTA-9634635", "name": "Estrogen-stimulated signaling through PRKCZ", "reactions": [ "reaction_10091271", "reaction_10091260", "reaction_10091275" ] }, "R-BTA-1234158": { "id": "pathway_10093984", "reactome": "R-BTA-1234158", "name": "Regulation of gene expression by Hypoxia-inducible Factor", "reactions": [ "reaction_10056679" ] }, "R-BTA-9696264": { "id": "pathway_10095028", "reactome": "R-BTA-9696264", "name": "RND3 GTPase cycle", "reactions": [ "reaction_10092002", "reaction_10092020" ] }, "R-BTA-1483101": { "id": "pathway_10094114", "reactome": "R-BTA-1483101", "name": "Synthesis of PS", "reactions": [ "reaction_10059073", "reaction_10059121" ] }, "R-BTA-9026290": { "id": "pathway_10094934", "reactome": "R-BTA-9026290", "name": "Biosynthesis of DPAn-3-derived maresins", "reactions": [ "reaction_10090472", "reaction_10090474" ] }, "R-BTA-9711123": { "id": "pathway_10092552", "reactome": "R-BTA-9711123", "name": "Cellular response to chemical stress", "reactions": [ "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10087866", "reaction_10067398", "reaction_10067744", "reaction_10092308", "reaction_10034166", "reaction_10080786", "reaction_10092310", "reaction_10068578", "reaction_10067416", "reaction_10067735", "reaction_10040636", "reaction_10068575", "reaction_10092293", "reaction_10092287", "reaction_10069854", "reaction_10076891", "reaction_10067375", "reaction_10067731", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273", "reaction_10038647", "reaction_10092239", "reaction_10092214", "reaction_10047807" ] }, "R-BTA-432040": { "id": "pathway_10093642", "reactome": "R-BTA-432040", "name": "Vasopressin regulates renal water homeostasis via Aquaporins", "reactions": [ "reaction_10049243", "reaction_10047483", "reaction_10049253", "reaction_10049241", "reaction_10049262" ] }, "R-BTA-9709957": { "id": "pathway_10092630", "reactome": "R-BTA-9709957", "name": "Sensory Perception", "reactions": [ "reaction_10065683", "reaction_10065597", "reaction_10035596", "reaction_10054382", "reaction_10054404", "reaction_10065644", "reaction_10035406", "reaction_10065604", "reaction_10065675", "reaction_10065664", "reaction_10088914", "reaction_10065944", "reaction_10035558", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065445", "reaction_10065673", "reaction_10066247", "reaction_10065437", "reaction_10054393", "reaction_10065441", "reaction_10066249", "reaction_10070971", "reaction_10069948", "reaction_10065679", "reaction_10065606", "reaction_10035619", "reaction_10077751", "reaction_10077744", "reaction_10065940", "reaction_10065677", "reaction_10035579", "reaction_10065808", "reaction_10065646", "reaction_10054375", "reaction_10054395" ] }, "R-BTA-69618": { "id": "pathway_10092900", "reactome": "R-BTA-69618", "name": "Mitotic Spindle Checkpoint", "reactions": [ "reaction_10038033", "reaction_10038035" ] }, "R-BTA-3700989": { "id": "pathway_10092434", "reactome": "R-BTA-3700989", "name": "Transcriptional Regulation by TP53", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10082931", "reaction_10066870", "reaction_10081380", "reaction_10081877", "reaction_10080738", "reaction_10078731", "reaction_10081291", "reaction_10033535", "reaction_10080730", "reaction_10081629", "reaction_10083072", "reaction_10082923", "reaction_10081323", "reaction_10033592", "reaction_10080789", "reaction_10081541", "reaction_10066764", "reaction_10046588", "reaction_10078349", "reaction_10033755", "reaction_10081522", "reaction_10034166", "reaction_10081278", "reaction_10080797", "reaction_10072591", "reaction_10081274", "reaction_10066704", "reaction_10082934", "reaction_10066684", "reaction_10088542", "reaction_10081293", "reaction_10038647", "reaction_10072550", "reaction_10081470", "reaction_10072614", "reaction_10081563", "reaction_10081602", "reaction_10066724", "reaction_10066670", "reaction_10072595", "reaction_10077955", "reaction_10066737", "reaction_10086155", "reaction_10076341", "reaction_10083092", "reaction_10081530", "reaction_10078474", "reaction_10083077", "reaction_10078408", "reaction_10072557", "reaction_10088546", "reaction_10081326", "reaction_10078720", "reaction_10078658", "reaction_10081499", "reaction_10081595", "reaction_10066712", "reaction_10088534", "reaction_10081305", "reaction_10081286", "reaction_10081622", "reaction_10081889", "reaction_10072571", "reaction_10080811", "reaction_10080457", "reaction_10081561" ] }, "R-BTA-163615": { "id": "pathway_10092802", "reactome": "R-BTA-163615", "name": "PKA activation", "reactions": [ "reaction_10037004" ] }, "R-BTA-2142696": { "id": "pathway_10094242", "reactome": "R-BTA-2142696", "name": "Synthesis of Hepoxilins (HX) and Trioxilins (TrX)", "reactions": [ "reaction_10064506" ] }, "R-BTA-69183": { "id": "pathway_10092424", "reactome": "R-BTA-69183", "name": "Processive synthesis on the lagging strand", "reactions": [ "reaction_10033504" ] }, "R-BTA-1614517": { "id": "pathway_10094132", "reactome": "R-BTA-1614517", "name": "Sulfide oxidation to sulfate", "reactions": [ "reaction_10060218", "reaction_10060361", "reaction_10060250", "reaction_10060216" ] }, "R-BTA-9668328": { "id": "pathway_10095014", "reactome": "R-BTA-9668328", "name": "Sealing of the nuclear envelope (NE) by ESCRT-III", "reactions": [ "reaction_10091661", "reaction_10091656", "reaction_10091634", "reaction_10091658" ] }, "R-BTA-73886": { "id": "pathway_10092966", "reactome": "R-BTA-73886", "name": "Chromosome Maintenance", "reactions": [ "reaction_10051465", "reaction_10038947", "reaction_10051451", "reaction_10051463", "reaction_10091663", "reaction_10038540", "reaction_10091685", "reaction_10038534", "reaction_10038949", "reaction_10051461" ] }, "R-BTA-1250196": { "id": "pathway_10094012", "reactome": "R-BTA-1250196", "name": "SHC1 events in ERBB2 signaling", "reactions": [ "reaction_10057139", "reaction_10086415" ] }, "R-BTA-432142": { "id": "pathway_10093418", "reactome": "R-BTA-432142", "name": "Platelet sensitization by LDL", "reactions": [ "reaction_10049283", "reaction_10044018", "reaction_10049290", "reaction_10049364", "reaction_10044043" ] }, "R-BTA-1663150": { "id": "pathway_10094126", "reactome": "R-BTA-1663150", "name": "The activation of arylsulfatases", "reactions": [ "reaction_10060109" ] }, "R-BTA-5654695": { "id": "pathway_10094544", "reactome": "R-BTA-5654695", "name": "PI-3K cascade:FGFR2", "reactions": [ "reaction_10073231" ] }, "R-BTA-9603798": { "id": "pathway_10094970", "reactome": "R-BTA-9603798", "name": "Class I peroxisomal membrane protein import", "reactions": [ "reaction_10090770" ] }, "R-BTA-936837": { "id": "pathway_10093670", "reactome": "R-BTA-936837", "name": "Ion transport by P-type ATPases", "reactions": [ "reaction_10076179", "reaction_10047893", "reaction_10076172", "reaction_10053143", "reaction_10053180", "reaction_10048787", "reaction_10053210", "reaction_10071254", "reaction_10053258", "reaction_10091759", "reaction_10047900" ] }, "R-BTA-1362409": { "id": "pathway_10094072", "reactome": "R-BTA-1362409", "name": "Mitochondrial iron-sulfur cluster biogenesis", "reactions": [ "reaction_10057787", "reaction_10086272", "reaction_10057792" ] }, "R-BTA-388396": { "id": "pathway_10092778", "reactome": "R-BTA-388396", "name": "GPCR downstream signalling", "reactions": [ "reaction_10037037", "reaction_10043315", "reaction_10089211", "reaction_10039653", "reaction_10089207", "reaction_10064915", "reaction_10048580", "reaction_10037045", "reaction_10047468", "reaction_10039676", "reaction_10048543", "reaction_10088940", "reaction_10089228", "reaction_10051656", "reaction_10039667", "reaction_10084016", "reaction_10047979", "reaction_10047498", "reaction_10089224", "reaction_10089222", "reaction_10083951", "reaction_10047947", "reaction_10037332", "reaction_10047552", "reaction_10039671", "reaction_10089203", "reaction_10039674", "reaction_10064919", "reaction_10048587", "reaction_10036959", "reaction_10039664", "reaction_10047823", "reaction_10037330", "reaction_10039658", "reaction_10046149", "reaction_10088962", "reaction_10047956", "reaction_10076743", "reaction_10089226", "reaction_10089167", "reaction_10089214", "reaction_10089197", "reaction_10037024", "reaction_10048170", "reaction_10036981", "reaction_10089217", "reaction_10037549", "reaction_10037022", "reaction_10037004", "reaction_10048370", "reaction_10064910", "reaction_10041950", "reaction_10049478", "reaction_10039485", "reaction_10046534", "reaction_10048632", "reaction_10048660", "reaction_10092055", "reaction_10039651", "reaction_10051667", "reaction_10091247", "reaction_10088942" ] }, "R-BTA-5362517": { "id": "pathway_10093324", "reactome": "R-BTA-5362517", "name": "Signaling by Retinoic Acid", "reactions": [ "reaction_10071407", "reaction_10071659", "reaction_10071648", "reaction_10071668", "reaction_10042860", "reaction_10071678", "reaction_10072397", "reaction_10044211", "reaction_10071691", "reaction_10072630", "reaction_10076840", "reaction_10072433", "reaction_10072628", "reaction_10072225", "reaction_10071397", "reaction_10071673" ] }, "R-BTA-202424": { "id": "pathway_10093348", "reactome": "R-BTA-202424", "name": "Downstream TCR signaling", "reactions": [ "reaction_10043219", "reaction_10043212", "reaction_10043302", "reaction_10043300", "reaction_10043298", "reaction_10043193", "reaction_10043270", "reaction_10043304", "reaction_10043252", "reaction_10043244", "reaction_10043225", "reaction_10043182", "reaction_10043274" ] }, "R-BTA-8957275": { "id": "pathway_10094846", "reactome": "R-BTA-8957275", "name": "Post-translational protein phosphorylation", "reactions": [ "reaction_10088473" ] }, "R-BTA-1592389": { "id": "pathway_10094118", "reactome": "R-BTA-1592389", "name": "Activation of Matrix Metalloproteinases", "reactions": [ "reaction_10059902", "reaction_10059913", "reaction_10059744", "reaction_10060003", "reaction_10059689", "reaction_10059918", "reaction_10059731", "reaction_10059869", "reaction_10059787", "reaction_10059923", "reaction_10059804" ] }, "R-BTA-6807047": { "id": "pathway_10093278", "reactome": "R-BTA-6807047", "name": "Cholesterol biosynthesis via desmosterol", "reactions": [ "reaction_10041664", "reaction_10041728", "reaction_10041671" ] }, "R-BTA-3134963": { "id": "pathway_10094328", "reactome": "R-BTA-3134963", "name": "DEx/H-box helicases activate type I IFN and inflammatory cytokines production ", "reactions": [ "reaction_10090837", "reaction_10066559" ] }, "R-BTA-194315": { "id": "pathway_10093368", "reactome": "R-BTA-194315", "name": "Signaling by Rho GTPases", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10072515", "reaction_10073503", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] }, "R-BTA-2565942": { "id": "pathway_10094312", "reactome": "R-BTA-2565942", "name": "Regulation of PLK1 Activity at G2/M Transition", "reactions": [ "reaction_10066489", "reaction_10066487", "reaction_10065938" ] }, "R-BTA-451308": { "id": "pathway_10093812", "reactome": "R-BTA-451308", "name": "Activation of Ca-permeable Kainate Receptor", "reactions": [ "reaction_10050514", "reaction_10050517" ] }, "R-BTA-2173795": { "id": "pathway_10094270", "reactome": "R-BTA-2173795", "name": "Downregulation of SMAD2/3:SMAD4 transcriptional activity", "reactions": [ "reaction_10064933" ] }, "R-BTA-5213460": { "id": "pathway_10094368", "reactome": "R-BTA-5213460", "name": "RIPK1-mediated regulated necrosis", "reactions": [ "reaction_10091779", "reaction_10070684", "reaction_10070534", "reaction_10070689", "reaction_10091773", "reaction_10072346", "reaction_10074254", "reaction_10091793", "reaction_10070531", "reaction_10071534", "reaction_10091808", "reaction_10074240", "reaction_10091806", "reaction_10068030", "reaction_10091810", "reaction_10070682", "reaction_10091783" ] }, "R-BTA-5621480": { "id": "pathway_10094492", "reactome": "R-BTA-5621480", "name": "Dectin-2 family", "reactions": [ "reaction_10072364", "reaction_10072383", "reaction_10072388", "reaction_10072392", "reaction_10072374", "reaction_10084636", "reaction_10072395" ] }, "R-BTA-1855183": { "id": "pathway_10094170", "reactome": "R-BTA-1855183", "name": "Synthesis of IP2, IP, and Ins in the cytosol", "reactions": [ "reaction_10061067", "reaction_10060938", "reaction_10061046", "reaction_10060986", "reaction_10061061", "reaction_10061064", "reaction_10061014", "reaction_10061134" ] }, "R-BTA-8847453": { "id": "pathway_10094696", "reactome": "R-BTA-8847453", "name": "Synthesis of PIPs in the nucleus", "reactions": [ "reaction_10082931", "reaction_10082934", "reaction_10083092" ] }, "R-BTA-69563": { "id": "pathway_10092444", "reactome": "R-BTA-69563", "name": "p53-Dependent G1 DNA Damage Response", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-193048": { "id": "pathway_10093254", "reactome": "R-BTA-193048", "name": "Androgen biosynthesis", "reactions": [ "reaction_10050650", "reaction_10041293", "reaction_10092065", "reaction_10041295", "reaction_10041290", "reaction_10041297", "reaction_10041284", "reaction_10092062" ] }, "R-BTA-382556": { "id": "pathway_10093468", "reactome": "R-BTA-382556", "name": "ABC-family proteins mediated transport", "reactions": [ "reaction_10074686", "reaction_10058216", "reaction_10074360", "reaction_10070728", "reaction_10058469", "reaction_10046707", "reaction_10046698", "reaction_10074493", "reaction_10057832", "reaction_10070743", "reaction_10044666" ] }, "R-BTA-6804760": { "id": "pathway_10094338", "reactome": "R-BTA-6804760", "name": "Regulation of TP53 Activity through Methylation", "reactions": [ "reaction_10066737", "reaction_10081877" ] }, "R-BTA-912694": { "id": "pathway_10093950", "reactome": "R-BTA-912694", "name": "Regulation of IFNA signaling", "reactions": [ "reaction_10055946", "reaction_10055955", "reaction_10055958" ] }, "R-BTA-8866910": { "id": "pathway_10093534", "reactome": "R-BTA-8866910", "name": "TFAP2 (AP-2) family regulates transcription of growth factors and their receptors", "reactions": [ "reaction_10045744" ] }, "R-BTA-112399": { "id": "pathway_10092640", "reactome": "R-BTA-112399", "name": "IRS-mediated signalling", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-2173796": { "id": "pathway_10094440", "reactome": "R-BTA-2173796", "name": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription", "reactions": [ "reaction_10071262" ] }, "R-BTA-5357786": { "id": "pathway_10092878", "reactome": "R-BTA-5357786", "name": "TNFR1-induced proapoptotic signaling", "reactions": [ "reaction_10037964" ] }, "R-BTA-8964539": { "id": "pathway_10092492", "reactome": "R-BTA-8964539", "name": "Glutamate and glutamine metabolism", "reactions": [ "reaction_10051165", "reaction_10033755", "reaction_10033757", "reaction_10033746", "reaction_10052046", "reaction_10077444", "reaction_10087455", "reaction_10077453" ] }, "R-BTA-193634": { "id": "pathway_10093266", "reactome": "R-BTA-193634", "name": "Axonal growth inhibition (RHOA activation)", "reactions": [ "reaction_10041470" ] }, "R-BTA-2173793": { "id": "pathway_10094272", "reactome": "R-BTA-2173793", "name": "Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer", "reactions": [ "reaction_10064933", "reaction_10071262" ] }, "R-BTA-75105": { "id": "pathway_10093332", "reactome": "R-BTA-75105", "name": "Fatty acyl-CoA biosynthesis", "reactions": [ "reaction_10042961", "reaction_10083389", "reaction_10051252", "reaction_10074353", "reaction_10051261" ] }, "R-BTA-2485179": { "id": "pathway_10092624", "reactome": "R-BTA-2485179", "name": "Activation of the phototransduction cascade", "reactions": [ "reaction_10035406" ] }, "R-BTA-1169092": { "id": "pathway_10093964", "reactome": "R-BTA-1169092", "name": "Activation of RAS in B cells", "reactions": [ "reaction_10056239" ] }, "R-BTA-1442490": { "id": "pathway_10094076", "reactome": "R-BTA-1442490", "name": "Collagen degradation", "reactions": [ "reaction_10059441", "reaction_10064649", "reaction_10076984", "reaction_10059651", "reaction_10059598", "reaction_10058193", "reaction_10059533", "reaction_10058561", "reaction_10064705" ] }, "R-BTA-73857": { "id": "pathway_10092438", "reactome": "R-BTA-73857", "name": "RNA Polymerase II Transcription", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10037185", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10037201", "reaction_10087900", "reaction_10088482", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-1253288": { "id": "pathway_10094022", "reactome": "R-BTA-1253288", "name": "Downregulation of ERBB4 signaling", "reactions": [ "reaction_10057262", "reaction_10090971", "reaction_10057264" ] }, "R-BTA-187015": { "id": "pathway_10093014", "reactome": "R-BTA-187015", "name": "Activation of TRKA receptors", "reactions": [ "reaction_10039270", "reaction_10039272", "reaction_10040684" ] }, "R-BTA-901032": { "id": "pathway_10093952", "reactome": "R-BTA-901032", "name": "ER Quality Control Compartment (ERQC)", "reactions": [ "reaction_10056058" ] }, "R-BTA-8866904": { "id": "pathway_10094784", "reactome": "R-BTA-8866904", "name": "Negative regulation of activity of TFAP2 (AP-2) family transcription factors", "reactions": [ "reaction_10084903", "reaction_10084909" ] }, "R-BTA-5684996": { "id": "pathway_10094570", "reactome": "R-BTA-5684996", "name": "MAPK1/MAPK3 signaling", "reactions": [ "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10091490", "reaction_10073904", "reaction_10091506", "reaction_10073932", "reaction_10074238", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10074088", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10073940", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-1358803": { "id": "pathway_10094068", "reactome": "R-BTA-1358803", "name": "Downregulation of ERBB2:ERBB3 signaling", "reactions": [ "reaction_10057712", "reaction_10057735", "reaction_10057740", "reaction_10057719", "reaction_10057742", "reaction_10057744" ] }, "R-BTA-3928665": { "id": "pathway_10094392", "reactome": "R-BTA-3928665", "name": "EPH-ephrin mediated repulsion of cells", "reactions": [ "reaction_10069285", "reaction_10069159", "reaction_10069157" ] }, "R-BTA-5661231": { "id": "pathway_10094550", "reactome": "R-BTA-5661231", "name": "Metallothioneins bind metals", "reactions": [ "reaction_10073446", "reaction_10073481", "reaction_10073460", "reaction_10073468", "reaction_10073464" ] }, "R-BTA-418592": { "id": "pathway_10093662", "reactome": "R-BTA-418592", "name": "ADP signalling through P2Y purinoceptor 1", "reactions": [ "reaction_10049039", "reaction_10047985", "reaction_10047870" ] }, "R-BTA-77346": { "id": "pathway_10092716", "reactome": "R-BTA-77346", "name": "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA", "reactions": [ "reaction_10036040", "reaction_10036042" ] }, "R-BTA-168142": { "id": "pathway_10093036", "reactome": "R-BTA-168142", "name": "Toll Like Receptor 10 (TLR10) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-3000171": { "id": "pathway_10094280", "reactome": "R-BTA-3000171", "name": "Non-integrin membrane-ECM interactions", "reactions": [ "reaction_10065292" ] }, "R-BTA-193368": { "id": "pathway_10093238", "reactome": "R-BTA-193368", "name": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol", "reactions": [ "reaction_10041197", "reaction_10041172", "reaction_10041308", "reaction_10041177", "reaction_10041208", "reaction_10041104", "reaction_10041226", "reaction_10041323", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041327", "reaction_10041210", "reaction_10041317", "reaction_10041204", "reaction_10041319", "reaction_10041179", "reaction_10041301" ] }, "R-BTA-390651": { "id": "pathway_10093614", "reactome": "R-BTA-390651", "name": "Dopamine receptors", "reactions": [ "reaction_10091556", "reaction_10047224", "reaction_10047222" ] }, "R-BTA-2404192": { "id": "pathway_10092652", "reactome": "R-BTA-2404192", "name": "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)", "reactions": [ "reaction_10075063", "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10036570", "reaction_10035507", "reaction_10036607" ] }, "R-BTA-6806003": { "id": "pathway_10094334", "reactome": "R-BTA-6806003", "name": "Regulation of TP53 Expression and Degradation", "reactions": [ "reaction_10066684", "reaction_10081541", "reaction_10078408", "reaction_10081561" ] }, "R-BTA-109581": { "id": "pathway_10092620", "reactome": "R-BTA-109581", "name": "Apoptosis", "reactions": [ "reaction_10044568", "reaction_10044116", "reaction_10043049", "reaction_10068042", "reaction_10037731", "reaction_10037991", "reaction_10044146", "reaction_10051175", "reaction_10037678", "reaction_10043039", "reaction_10044756", "reaction_10037706", "reaction_10037618", "reaction_10037253", "reaction_10044762", "reaction_10068046", "reaction_10044995", "reaction_10044896", "reaction_10044927", "reaction_10044869", "reaction_10037723", "reaction_10091191", "reaction_10035396", "reaction_10044578", "reaction_10037702", "reaction_10037277", "reaction_10091197", "reaction_10037293", "reaction_10081897", "reaction_10037630", "reaction_10067891", "reaction_10038007", "reaction_10044142", "reaction_10091186", "reaction_10091188", "reaction_10051181", "reaction_10043059", "reaction_10044680", "reaction_10037739", "reaction_10037237", "reaction_10043021", "reaction_10090573", "reaction_10037674", "reaction_10039520", "reaction_10044923", "reaction_10090575", "reaction_10037289", "reaction_10037264", "reaction_10037727", "reaction_10037985", "reaction_10044144", "reaction_10037622", "reaction_10044906", "reaction_10067895", "reaction_10037641" ] }, "R-BTA-1963642": { "id": "pathway_10094064", "reactome": "R-BTA-1963642", "name": "PI3K events in ERBB2 signaling", "reactions": [ "reaction_10057700" ] }, "R-BTA-913531": { "id": "pathway_10093860", "reactome": "R-BTA-913531", "name": "Interferon Signaling", "reactions": [ "reaction_10052229", "reaction_10052217", "reaction_10052213", "reaction_10056315", "reaction_10051762", "reaction_10091723", "reaction_10089341", "reaction_10051696", "reaction_10089703", "reaction_10051818", "reaction_10055955", "reaction_10060730", "reaction_10055958", "reaction_10051792", "reaction_10089696", "reaction_10056289", "reaction_10052159", "reaction_10055946", "reaction_10051737", "reaction_10070719", "reaction_10056283", "reaction_10055967", "reaction_10052233", "reaction_10052189", "reaction_10052196", "reaction_10052236", "reaction_10051786", "reaction_10052067", "reaction_10089349", "reaction_10060694", "reaction_10056287", "reaction_10052210", "reaction_10052147", "reaction_10051780", "reaction_10051748", "reaction_10051771", "reaction_10060732", "reaction_10051774", "reaction_10056297", "reaction_10052347", "reaction_10091725" ] }, "R-BTA-156581": { "id": "pathway_10092694", "reactome": "R-BTA-156581", "name": "Methylation", "reactions": [ "reaction_10035863", "reaction_10071924", "reaction_10076900", "reaction_10038238", "reaction_10039930", "reaction_10076903", "reaction_10076898" ] }, "R-BTA-109582": { "id": "pathway_10092842", "reactome": "R-BTA-109582", "name": "Hemostasis", "reactions": [ "reaction_10037913", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10090718", "reaction_10049300", "reaction_10047475", "reaction_10053213", "reaction_10038303", "reaction_10047893", "reaction_10048587", "reaction_10043323", "reaction_10038329", "reaction_10050994", "reaction_10055920", "reaction_10076743", "reaction_10037927", "reaction_10043375", "reaction_10037353", "reaction_10056002", "reaction_10038201", "reaction_10048635", "reaction_10037852", "reaction_10049071", "reaction_10091701", "reaction_10055831", "reaction_10091546", "reaction_10037588", "reaction_10055833", "reaction_10071906", "reaction_10037895", "reaction_10038307", "reaction_10055649", "reaction_10043363", "reaction_10071946", "reaction_10051002", "reaction_10043355", "reaction_10037923", "reaction_10037948", "reaction_10044030", "reaction_10038288", "reaction_10049279", "reaction_10055823", "reaction_10085323", "reaction_10065227", "reaction_10037557", "reaction_10037800", "reaction_10037937", "reaction_10037899", "reaction_10037915", "reaction_10049039", "reaction_10047212", "reaction_10055870", "reaction_10055647", "reaction_10049506", "reaction_10037433", "reaction_10055827", "reaction_10047857", "reaction_10038213", "reaction_10055515", "reaction_10092299", "reaction_10048580", "reaction_10048543", "reaction_10050870", "reaction_10044043", "reaction_10038285", "reaction_10037845", "reaction_10048504", "reaction_10048182", "reaction_10055995", "reaction_10055933", "reaction_10044039", "reaction_10047930", "reaction_10038270", "reaction_10038290", "reaction_10038263", "reaction_10037517", "reaction_10043347", "reaction_10055829", "reaction_10037887", "reaction_10066263", "reaction_10047900", "reaction_10049283", "reaction_10044018", "reaction_10051062", "reaction_10037607", "reaction_10055645", "reaction_10038221", "reaction_10044034", "reaction_10048632", "reaction_10037950", "reaction_10037815", "reaction_10048660", "reaction_10038166", "reaction_10037580", "reaction_10055529", "reaction_10049364", "reaction_10049067", "reaction_10037906", "reaction_10050630", "reaction_10049290", "reaction_10090183", "reaction_10043335", "reaction_10090181", "reaction_10049014", "reaction_10038205", "reaction_10050948", "reaction_10047907", "reaction_10043397", "reaction_10049035", "reaction_10044024", "reaction_10049426", "reaction_10049395", "reaction_10047870", "reaction_10047880", "reaction_10047380", "reaction_10090185", "reaction_10045016", "reaction_10055847", "reaction_10091671", "reaction_10047985", "reaction_10047886", "reaction_10044020", "reaction_10043393", "reaction_10050924", "reaction_10085753", "reaction_10038292" ] }, "R-BTA-383280": { "id": "pathway_10093556", "reactome": "R-BTA-383280", "name": "Nuclear Receptor transcription pathway", "reactions": [ "reaction_10046681" ] }, "R-BTA-2408508": { "id": "pathway_10094286", "reactome": "R-BTA-2408508", "name": "Metabolism of ingested SeMet, Sec, MeSec into H2Se", "reactions": [ "reaction_10065455" ] }, "R-BTA-1300645": { "id": "pathway_10094046", "reactome": "R-BTA-1300645", "name": "Acrosome Reaction and Sperm:Oocyte Membrane Binding", "reactions": [ "reaction_10057605", "reaction_10057598" ] }, "R-BTA-1483255": { "id": "pathway_10094144", "reactome": "R-BTA-1483255", "name": "PI Metabolism", "reactions": [ "reaction_10060537", "reaction_10082931", "reaction_10060550", "reaction_10082147", "reaction_10060473", "reaction_10085697", "reaction_10060516", "reaction_10082136", "reaction_10060572", "reaction_10060518", "reaction_10060514", "reaction_10060611", "reaction_10082152", "reaction_10060614", "reaction_10085784", "reaction_10082155", "reaction_10060483", "reaction_10060468", "reaction_10060569", "reaction_10085780", "reaction_10082934", "reaction_10060501", "reaction_10060553", "reaction_10060597", "reaction_10060600", "reaction_10060595", "reaction_10060590", "reaction_10083092", "reaction_10060574", "reaction_10060558", "reaction_10060588", "reaction_10060476", "reaction_10060579", "reaction_10083800", "reaction_10060556", "reaction_10085775", "reaction_10085843", "reaction_10060448", "reaction_10060429", "reaction_10083369", "reaction_10060461", "reaction_10083211", "reaction_10060498", "reaction_10060535" ] }, "R-BTA-9033807": { "id": "pathway_10094958", "reactome": "R-BTA-9033807", "name": "ABO blood group biosynthesis", "reactions": [ "reaction_10090620", "reaction_10090631", "reaction_10090611", "reaction_10090645", "reaction_10090703", "reaction_10090638" ] }, "R-BTA-5654706": { "id": "pathway_10094528", "reactome": "R-BTA-5654706", "name": "FRS-mediated FGFR3 signaling", "reactions": [ "reaction_10073014", "reaction_10073021", "reaction_10073147", "reaction_10073011", "reaction_10087376", "reaction_10073019", "reaction_10073145" ] }, "R-BTA-187037": { "id": "pathway_10093016", "reactome": "R-BTA-187037", "name": "Signaling by NTRK1 (TRKA)", "reactions": [ "reaction_10090994", "reaction_10039272", "reaction_10043315", "reaction_10041917", "reaction_10041869", "reaction_10039601", "reaction_10039736", "reaction_10041851", "reaction_10040570", "reaction_10039270", "reaction_10042826", "reaction_10039581", "reaction_10040684", "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090954", "reaction_10074879", "reaction_10039592", "reaction_10041950", "reaction_10090944", "reaction_10043488", "reaction_10039711" ] }, "R-BTA-5576886": { "id": "pathway_10094038", "reactome": "R-BTA-5576886", "name": "Phase 4 - resting membrane potential", "reactions": [ "reaction_10071876", "reaction_10057418" ] }, "R-BTA-444411": { "id": "pathway_10093770", "reactome": "R-BTA-444411", "name": "Rhesus glycoproteins mediate ammonium transport.", "reactions": [ "reaction_10049635", "reaction_10049871", "reaction_10049869", "reaction_10049628" ] }, "R-BTA-171319": { "id": "pathway_10092960", "reactome": "R-BTA-171319", "name": "Telomere Extension By Telomerase", "reactions": [ "reaction_10038534", "reaction_10038947", "reaction_10038540", "reaction_10038949" ] }, "R-BTA-5607761": { "id": "pathway_10094468", "reactome": "R-BTA-5607761", "name": "Dectin-1 mediated noncanonical NF-kB signaling", "reactions": [ "reaction_10072030", "reaction_10071975", "reaction_10071948", "reaction_10071982" ] }, "R-BTA-110330": { "id": "pathway_10095004", "reactome": "R-BTA-110330", "name": "Recognition and association of DNA glycosylase with site containing an affected purine", "reactions": [ "reaction_10091211", "reaction_10091566" ] }, "R-BTA-6814848": { "id": "pathway_10094714", "reactome": "R-BTA-6814848", "name": "Glycerophospholipid catabolism", "reactions": [ "reaction_10083211", "reaction_10083369" ] }, "R-BTA-2871796": { "id": "pathway_10093048", "reactome": "R-BTA-2871796", "name": "FCERI mediated MAPK activation", "reactions": [ "reaction_10050208", "reaction_10066151", "reaction_10066082", "reaction_10066065", "reaction_10039508", "reaction_10065491", "reaction_10050256" ] }, "R-BTA-8849471": { "id": "pathway_10094736", "reactome": "R-BTA-8849471", "name": "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases", "reactions": [ "reaction_10083690", "reaction_10083629", "reaction_10083695", "reaction_10083684", "reaction_10083622", "reaction_10083588", "reaction_10083697", "reaction_10083581" ] }, "R-BTA-76046": { "id": "pathway_10092684", "reactome": "R-BTA-76046", "name": "RNA Polymerase III Transcription Initiation", "reactions": [ "reaction_10035854" ] }, "R-BTA-418555": { "id": "pathway_10093680", "reactome": "R-BTA-418555", "name": "G alpha (s) signalling events", "reactions": [ "reaction_10083951", "reaction_10047947", "reaction_10089226", "reaction_10092055", "reaction_10089228", "reaction_10091247", "reaction_10084016" ] }, "R-BTA-9007101": { "id": "pathway_10094766", "reactome": "R-BTA-9007101", "name": "Rab regulation of trafficking", "reactions": [ "reaction_10085988", "reaction_10084238", "reaction_10086097", "reaction_10084291", "reaction_10086136", "reaction_10084276", "reaction_10085932", "reaction_10084246", "reaction_10086209", "reaction_10084261", "reaction_10084228", "reaction_10086019", "reaction_10086182", "reaction_10086054" ] }, "R-BTA-73884": { "id": "pathway_10092754", "reactome": "R-BTA-73884", "name": "Base Excision Repair", "reactions": [ "reaction_10036716", "reaction_10091566", "reaction_10091222", "reaction_10088526", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036767", "reaction_10036709", "reaction_10091211", "reaction_10036729", "reaction_10036798", "reaction_10036736", "reaction_10091233", "reaction_10091240", "reaction_10036743", "reaction_10036805" ] }, "R-BTA-390466": { "id": "pathway_10094718", "reactome": "R-BTA-390466", "name": "Chaperonin-mediated protein folding", "reactions": [ "reaction_10083231", "reaction_10083808" ] }, "R-BTA-5656169": { "id": "pathway_10094502", "reactome": "R-BTA-5656169", "name": "Termination of translesion DNA synthesis", "reactions": [ "reaction_10072883", "reaction_10072876", "reaction_10073302" ] }, "R-BTA-5653890": { "id": "pathway_10094504", "reactome": "R-BTA-5653890", "name": "Lactose synthesis", "reactions": [ "reaction_10072894", "reaction_10072898" ] }, "R-BTA-982772": { "id": "pathway_10093942", "reactome": "R-BTA-982772", "name": "Growth hormone receptor signaling", "reactions": [ "reaction_10056268", "reaction_10054779", "reaction_10054791" ] }, "R-BTA-400508": { "id": "pathway_10093562", "reactome": "R-BTA-400508", "name": "Incretin synthesis, secretion, and inactivation", "reactions": [ "reaction_10046723", "reaction_10048380" ] }, "R-BTA-5357769": { "id": "pathway_10092618", "reactome": "R-BTA-5357769", "name": "Caspase activation via extrinsic apoptotic signalling pathway", "reactions": [ "reaction_10068046", "reaction_10035396", "reaction_10068042", "reaction_10037991", "reaction_10037985", "reaction_10067895", "reaction_10067891" ] }, "R-BTA-8964058": { "id": "pathway_10093456", "reactome": "R-BTA-8964058", "name": "HDL remodeling", "reactions": [ "reaction_10044666", "reaction_10088982", "reaction_10044547" ] }, "R-BTA-169893": { "id": "pathway_10093080", "reactome": "R-BTA-169893", "name": "Prolonged ERK activation events", "reactions": [ "reaction_10090949", "reaction_10039601", "reaction_10039697", "reaction_10039581", "reaction_10039690", "reaction_10039592", "reaction_10090944", "reaction_10090954", "reaction_10039711" ] }, "R-BTA-8963889": { "id": "pathway_10094636", "reactome": "R-BTA-8963889", "name": "Assembly of active LPL and LIPC lipase complexes", "reactions": [ "reaction_10084509", "reaction_10077487", "reaction_10077489" ] }, "R-BTA-70895": { "id": "pathway_10092508", "reactome": "R-BTA-70895", "name": "Branched-chain amino acid catabolism", "reactions": [ "reaction_10033824", "reaction_10051185", "reaction_10033788", "reaction_10033797", "reaction_10033806" ] }, "R-BTA-6783310": { "id": "pathway_10094638", "reactome": "R-BTA-6783310", "name": "Fanconi Anemia Pathway", "reactions": [ "reaction_10077625", "reaction_10077593", "reaction_10077591" ] }, "R-BTA-5661270": { "id": "pathway_10094548", "reactome": "R-BTA-5661270", "name": "Formation of xylulose-5-phosphate", "reactions": [ "reaction_10073431", "reaction_10073438" ] }, "R-BTA-975577": { "id": "pathway_10093930", "reactome": "R-BTA-975577", "name": "N-Glycan antennae elongation", "reactions": [ "reaction_10056061", "reaction_10054418", "reaction_10054431", "reaction_10056074", "reaction_10054438", "reaction_10054467" ] }, "R-BTA-435354": { "id": "pathway_10093762", "reactome": "R-BTA-435354", "name": "Zinc transporters", "reactions": [ "reaction_10049392", "reaction_10049378", "reaction_10049440", "reaction_10049385", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-5693538": { "id": "pathway_10092680", "reactome": "R-BTA-5693538", "name": "Homology Directed Repair", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075306", "reaction_10074798", "reaction_10075151", "reaction_10075326", "reaction_10075304", "reaction_10076339", "reaction_10075037", "reaction_10035846", "reaction_10075181", "reaction_10075323", "reaction_10075319" ] }, "R-BTA-156842": { "id": "pathway_10092910", "reactome": "R-BTA-156842", "name": "Eukaryotic Translation Elongation", "reactions": [ "reaction_10038107" ] }, "R-BTA-379398": { "id": "pathway_10093538", "reactome": "R-BTA-379398", "name": "Enzymatic degradation of Dopamine by monoamine oxidase", "reactions": [ "reaction_10046151" ] }, "R-BTA-5358606": { "id": "pathway_10094454", "reactome": "R-BTA-5358606", "name": "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)", "reactions": [ "reaction_10071617", "reaction_10071765", "reaction_10071630" ] }, "R-BTA-6807062": { "id": "pathway_10094690", "reactome": "R-BTA-6807062", "name": "Cholesterol biosynthesis via lathosterol", "reactions": [ "reaction_10081990", "reaction_10081988", "reaction_10081986" ] }, "R-BTA-76009": { "id": "pathway_10093494", "reactome": "R-BTA-76009", "name": "Platelet Aggregation (Plug Formation)", "reactions": [ "reaction_10047212", "reaction_10053213", "reaction_10049506", "reaction_10045016", "reaction_10049279" ] }, "R-BTA-5654696": { "id": "pathway_10094508", "reactome": "R-BTA-5654696", "name": "Downstream signaling of activated FGFR2", "reactions": [ "reaction_10073133", "reaction_10073127", "reaction_10073129", "reaction_10087370", "reaction_10072931", "reaction_10072979", "reaction_10072976", "reaction_10073231", "reaction_10072929", "reaction_10073136", "reaction_10072999", "reaction_10072909", "reaction_10072993", "reaction_10073001", "reaction_10073004" ] }, "R-BTA-3249367": { "id": "pathway_10094344", "reactome": "R-BTA-3249367", "name": "STAT6-mediated induction of chemokines", "reactions": [ "reaction_10067233", "reaction_10067223", "reaction_10067216", "reaction_10067231", "reaction_10067229", "reaction_10067225" ] }, "R-BTA-9020558": { "id": "pathway_10093818", "reactome": "R-BTA-9020558", "name": "Interleukin-2 signaling", "reactions": [ "reaction_10051196", "reaction_10051194", "reaction_10091731", "reaction_10050527" ] }, "R-BTA-1237112": { "id": "pathway_10094006", "reactome": "R-BTA-1237112", "name": "Methionine salvage pathway", "reactions": [ "reaction_10057023", "reaction_10057684", "reaction_10057032" ] }, "R-BTA-1299361": { "id": "pathway_10094060", "reactome": "R-BTA-1299361", "name": "TWIK-related alkaline pH activated K+ channel (TALK)", "reactions": [ "reaction_10057682" ] }, "R-BTA-4419969": { "id": "pathway_10094400", "reactome": "R-BTA-4419969", "name": "Depolymerisation of the Nuclear Lamina", "reactions": [ "reaction_10070705", "reaction_10069491" ] }, "R-BTA-9617629": { "id": "pathway_10094992", "reactome": "R-BTA-9617629", "name": "Regulation of FOXO transcriptional activity by acetylation", "reactions": [ "reaction_10091096", "reaction_10091184", "reaction_10091089" ] }, "R-BTA-879518": { "id": "pathway_10093870", "reactome": "R-BTA-879518", "name": "Transport of organic anions", "reactions": [ "reaction_10051879", "reaction_10051866", "reaction_10051899", "reaction_10051843", "reaction_10091250" ] }, "R-BTA-74182": { "id": "pathway_10092610", "reactome": "R-BTA-74182", "name": "Ketone body metabolism", "reactions": [ "reaction_10035374", "reaction_10035415", "reaction_10035372", "reaction_10035363", "reaction_10035417" ] }, "R-BTA-5654743": { "id": "pathway_10093198", "reactome": "R-BTA-5654743", "name": "Signaling by FGFR4", "reactions": [ "reaction_10057327", "reaction_10072939", "reaction_10073222", "reaction_10040769", "reaction_10073192", "reaction_10073240", "reaction_10057314", "reaction_10057329", "reaction_10040776", "reaction_10087367", "reaction_10059156", "reaction_10053082", "reaction_10073166", "reaction_10057707", "reaction_10073044", "reaction_10057318", "reaction_10073175", "reaction_10073037", "reaction_10072933", "reaction_10057704", "reaction_10073031", "reaction_10073237", "reaction_10073184", "reaction_10073246", "reaction_10073177", "reaction_10073028", "reaction_10072927", "reaction_10073182", "reaction_10057323", "reaction_10073047", "reaction_10057337", "reaction_10073041", "reaction_10057302" ] }, "R-BTA-1606322": { "id": "pathway_10094208", "reactome": "R-BTA-1606322", "name": "ZBP1(DAI) mediated induction of type I IFNs", "reactions": [ "reaction_10065388", "reaction_10063376" ] }, "R-BTA-193639": { "id": "pathway_10093404", "reactome": "R-BTA-193639", "name": "p75NTR signals via NF-kB", "reactions": [ "reaction_10043877" ] }, "R-BTA-5675221": { "id": "pathway_10094576", "reactome": "R-BTA-5675221", "name": "Negative regulation of MAPK pathway", "reactions": [ "reaction_10074146", "reaction_10074231", "reaction_10074156", "reaction_10074184", "reaction_10074238", "reaction_10074148", "reaction_10074221" ] }, "R-BTA-202733": { "id": "pathway_10093362", "reactome": "R-BTA-202733", "name": "Cell surface interactions at the vascular wall", "reactions": [ "reaction_10044024", "reaction_10043347", "reaction_10044018", "reaction_10043375", "reaction_10066263", "reaction_10043363", "reaction_10044030", "reaction_10044034", "reaction_10043397", "reaction_10043393", "reaction_10044039", "reaction_10043355", "reaction_10043335", "reaction_10085753", "reaction_10044043", "reaction_10043323" ] }, "R-BTA-804914": { "id": "pathway_10093872", "reactome": "R-BTA-804914", "name": "Transport of fatty acids", "reactions": [ "reaction_10051892", "reaction_10070928" ] }, "R-BTA-561048": { "id": "pathway_10093834", "reactome": "R-BTA-561048", "name": "Organic anion transport", "reactions": [ "reaction_10051314", "reaction_10051305" ] }, "R-BTA-187687": { "id": "pathway_10093082", "reactome": "R-BTA-187687", "name": "Signalling to ERKs", "reactions": [ "reaction_10090949", "reaction_10039601", "reaction_10039697", "reaction_10039581", "reaction_10039690", "reaction_10039592", "reaction_10039736", "reaction_10040570", "reaction_10090944", "reaction_10090954", "reaction_10039711", "reaction_10074879" ] }, "R-BTA-1614558": { "id": "pathway_10094134", "reactome": "R-BTA-1614558", "name": "Degradation of cysteine and homocysteine", "reactions": [ "reaction_10060361", "reaction_10060250", "reaction_10060234", "reaction_10060216", "reaction_10060255", "reaction_10060228", "reaction_10060252", "reaction_10089959", "reaction_10060264", "reaction_10089850", "reaction_10090013", "reaction_10083204", "reaction_10090015", "reaction_10090671", "reaction_10060218", "reaction_10090679", "reaction_10090681" ] }, "R-BTA-5682910": { "id": "pathway_10094584", "reactome": "R-BTA-5682910", "name": "LGI-ADAM interactions", "reactions": [ "reaction_10074603", "reaction_10074613", "reaction_10074641" ] }, "R-BTA-1369062": { "id": "pathway_10093466", "reactome": "R-BTA-1369062", "name": "ABC transporters in lipid homeostasis", "reactions": [ "reaction_10074686", "reaction_10074493", "reaction_10044666", "reaction_10046707" ] }, "R-BTA-1502540": { "id": "pathway_10093974", "reactome": "R-BTA-1502540", "name": "Signaling by Activin", "reactions": [ "reaction_10056356", "reaction_10056354" ] }, "R-BTA-168181": { "id": "pathway_10093030", "reactome": "R-BTA-168181", "name": "Toll Like Receptor 7/8 (TLR7/8) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10053046", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10053048", "reaction_10091739", "reaction_10043488", "reaction_10039508", "reaction_10050256", "reaction_10050231", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-391908": { "id": "pathway_10093628", "reactome": "R-BTA-391908", "name": "Prostanoid ligand receptors", "reactions": [ "reaction_10047374", "reaction_10047394", "reaction_10047366", "reaction_10047380", "reaction_10047376" ] }, "R-BTA-111885": { "id": "pathway_10092774", "reactome": "R-BTA-111885", "name": "Opioid Signalling", "reactions": [ "reaction_10037037", "reaction_10037022", "reaction_10037004", "reaction_10039653", "reaction_10036981", "reaction_10039671", "reaction_10037045", "reaction_10039674", "reaction_10049478", "reaction_10039485", "reaction_10039676", "reaction_10036959", "reaction_10039651", "reaction_10037024", "reaction_10039667", "reaction_10039658", "reaction_10039664" ] }, "R-BTA-6805567": { "id": "pathway_10094654", "reactome": "R-BTA-6805567", "name": "Keratinization", "reactions": [ "reaction_10081857", "reaction_10083824", "reaction_10081921", "reaction_10082871", "reaction_10081917", "reaction_10083741", "reaction_10083743", "reaction_10081915", "reaction_10083835", "reaction_10081861", "reaction_10077943" ] }, "R-BTA-8963676": { "id": "pathway_10094810", "reactome": "R-BTA-8963676", "name": "Intestinal absorption", "reactions": [ "reaction_10086350" ] }, "R-BTA-1500931": { "id": "pathway_10093622", "reactome": "R-BTA-1500931", "name": "Cell-Cell communication", "reactions": [ "reaction_10048352", "reaction_10049883", "reaction_10049312", "reaction_10048065", "reaction_10047292", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10049304", "reaction_10049891", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-73927": { "id": "pathway_10092758", "reactome": "R-BTA-73927", "name": "Depurination", "reactions": [ "reaction_10091566", "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10091211", "reaction_10036798", "reaction_10091233", "reaction_10091240", "reaction_10036805" ] }, "R-BTA-375281": { "id": "pathway_10093624", "reactome": "R-BTA-375281", "name": "Hormone ligand-binding receptors", "reactions": [ "reaction_10047362", "reaction_10047354", "reaction_10047334" ] }, "R-BTA-163765": { "id": "pathway_10092992", "reactome": "R-BTA-163765", "name": "ChREBP activates metabolic gene expression", "reactions": [ "reaction_10038942" ] }, "R-BTA-9006934": { "id": "pathway_10092646", "reactome": "R-BTA-9006934", "name": "Signaling by Receptor Tyrosine Kinases", "reactions": [ "reaction_10090994", "reaction_10072979", "reaction_10040286", "reaction_10073147", "reaction_10057327", "reaction_10040393", "reaction_10040769", "reaction_10071504", "reaction_10072993", "reaction_10041917", "reaction_10040229", "reaction_10040744", "reaction_10040451", "reaction_10040779", "reaction_10057139", "reaction_10041463", "reaction_10040462", "reaction_10075063", "reaction_10057862", "reaction_10039736", "reaction_10073077", "reaction_10073234", "reaction_10057188", "reaction_10044470", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10039581", "reaction_10053082", "reaction_10057252", "reaction_10084849", "reaction_10090949", "reaction_10070676", "reaction_10039697", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10056781", "reaction_10072999", "reaction_10087373", "reaction_10086415", "reaction_10073102", "reaction_10073001", "reaction_10040447", "reaction_10073031", "reaction_10040277", "reaction_10090675", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10040421", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043488", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10061492", "reaction_10057184", "reaction_10040331", "reaction_10075065", "reaction_10090722", "reaction_10057236", "reaction_10039272", "reaction_10072946", "reaction_10073326", "reaction_10040489", "reaction_10057191", "reaction_10072939", "reaction_10073108", "reaction_10040289", "reaction_10040258", "reaction_10057286", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10041869", "reaction_10091751", "reaction_10039601", "reaction_10073225", "reaction_10040432", "reaction_10035536", "reaction_10039270", "reaction_10057314", "reaction_10071508", "reaction_10073122", "reaction_10040326", "reaction_10058478", "reaction_10040696", "reaction_10070651", "reaction_10070645", "reaction_10057262", "reaction_10073133", "reaction_10057735", "reaction_10057700", "reaction_10057695", "reaction_10057854", "reaction_10073011", "reaction_10039690", "reaction_10073044", "reaction_10058474", "reaction_10065227", "reaction_10073228", "reaction_10072909", "reaction_10044465", "reaction_10090954", "reaction_10057704", "reaction_10074879", "reaction_10087370", "reaction_10080870", "reaction_10040773", "reaction_10073328", "reaction_10083477", "reaction_10084080", "reaction_10061458", "reaction_10040458", "reaction_10041950", "reaction_10083483", "reaction_10073071", "reaction_10040453", "reaction_10043832", "reaction_10040369", "reaction_10057337", "reaction_10057857", "reaction_10073041", "reaction_10040782", "reaction_10041453", "reaction_10040495", "reaction_10044472", "reaction_10057740", "reaction_10040317", "reaction_10035527", "reaction_10041649", "reaction_10073222", "reaction_10072929", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10057151", "reaction_10057872", "reaction_10057175", "reaction_10070628", "reaction_10046660", "reaction_10072976", "reaction_10041851", "reaction_10071506", "reaction_10046677", "reaction_10090727", "reaction_10073199", "reaction_10077601", "reaction_10046666", "reaction_10090971", "reaction_10070594", "reaction_10040386", "reaction_10073004", "reaction_10057177", "reaction_10077605", "reaction_10040303", "reaction_10038450", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10057744", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10036607", "reaction_10084067", "reaction_10073237", "reaction_10057867", "reaction_10073246", "reaction_10040720", "reaction_10058480", "reaction_10039592", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10057719", "reaction_10075097", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10040310", "reaction_10073215", "reaction_10057692", "reaction_10057845", "reaction_10073014", "reaction_10043315", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10040299", "reaction_10061480", "reaction_10057850", "reaction_10040323", "reaction_10090666", "reaction_10072920", "reaction_10070589", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10040570", "reaction_10036570", "reaction_10069535", "reaction_10057284", "reaction_10073242", "reaction_10087367", "reaction_10041657", "reaction_10073166", "reaction_10040684", "reaction_10083935", "reaction_10070615", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10057264", "reaction_10057298", "reaction_10091689", "reaction_10040704", "reaction_10057742", "reaction_10035507", "reaction_10073152", "reaction_10073140", "reaction_10057712", "reaction_10070657", "reaction_10072931", "reaction_10040460", "reaction_10036590", "reaction_10057166", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10073097", "reaction_10057272", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10039711", "reaction_10036616", "reaction_10057302" ] }, "R-BTA-2299718": { "id": "pathway_10094266", "reactome": "R-BTA-2299718", "name": "Condensation of Prophase Chromosomes", "reactions": [ "reaction_10065201", "reaction_10065563", "reaction_10065177", "reaction_10064904" ] }, "R-BTA-9006927": { "id": "pathway_10094726", "reactome": "R-BTA-9006927", "name": "Signaling by Non-Receptor Tyrosine Kinases", "reactions": [ "reaction_10083646", "reaction_10083695", "reaction_10083697", "reaction_10083487", "reaction_10083707", "reaction_10083676", "reaction_10083726", "reaction_10083672", "reaction_10083581", "reaction_10083729", "reaction_10083638", "reaction_10083652", "reaction_10083656", "reaction_10084466", "reaction_10083558", "reaction_10083588", "reaction_10083632", "reaction_10083664", "reaction_10083477", "reaction_10083690", "reaction_10083629", "reaction_10083565", "reaction_10083684", "reaction_10083483", "reaction_10083622" ] }, "R-BTA-5685942": { "id": "pathway_10094592", "reactome": "R-BTA-5685942", "name": "HDR through Homologous Recombination (HRR)", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075151" ] }, "R-BTA-205043": { "id": "pathway_10093392", "reactome": "R-BTA-205043", "name": "NRIF signals cell death from the nucleus", "reactions": [ "reaction_10043744", "reaction_10043739", "reaction_10043778" ] }, "R-BTA-5654693": { "id": "pathway_10094522", "reactome": "R-BTA-5654693", "name": "FRS-mediated FGFR1 signaling", "reactions": [ "reaction_10072957", "reaction_10073083", "reaction_10073090", "reaction_10073097", "reaction_10073108", "reaction_10087373", "reaction_10073106", "reaction_10073113" ] }, "R-BTA-2161541": { "id": "pathway_10094252", "reactome": "R-BTA-2161541", "name": "Abacavir metabolism", "reactions": [ "reaction_10064584" ] }, "R-BTA-446728": { "id": "pathway_10093690", "reactome": "R-BTA-446728", "name": "Cell junction organization", "reactions": [ "reaction_10048352", "reaction_10049883", "reaction_10049312", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10049304", "reaction_10049891", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-629597": { "id": "pathway_10093840", "reactome": "R-BTA-629597", "name": "Highly calcium permeable nicotinic acetylcholine receptors", "reactions": [ "reaction_10051498", "reaction_10051525" ] }, "R-BTA-5250941": { "id": "pathway_10093714", "reactome": "R-BTA-5250941", "name": "Negative epigenetic regulation of rRNA expression", "reactions": [ "reaction_10048682", "reaction_10048717", "reaction_10048720" ] }, "R-BTA-975110": { "id": "pathway_10093898", "reactome": "R-BTA-975110", "name": "TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling", "reactions": [ "reaction_10053048", "reaction_10053046" ] }, "R-BTA-110313": { "id": "pathway_10092762", "reactome": "R-BTA-110313", "name": "Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template", "reactions": [ "reaction_10072883", "reaction_10036886", "reaction_10073302", "reaction_10073279", "reaction_10036844", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036853", "reaction_10036879", "reaction_10072876", "reaction_10036869" ] }, "R-BTA-8983432": { "id": "pathway_10094868", "reactome": "R-BTA-8983432", "name": "Interleukin-15 signaling", "reactions": [ "reaction_10089291", "reaction_10089267", "reaction_10089269", "reaction_10089311" ] }, "R-BTA-167060": { "id": "pathway_10093146", "reactome": "R-BTA-167060", "name": "NGF processing", "reactions": [ "reaction_10040489", "reaction_10040495" ] }, "R-BTA-442729": { "id": "pathway_10092794", "reactome": "R-BTA-442729", "name": "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde", "reactions": [ "reaction_10049478", "reaction_10036981" ] }, "R-BTA-198753": { "id": "pathway_10093304", "reactome": "R-BTA-198753", "name": "ERK/MAPK targets", "reactions": [ "reaction_10042826", "reaction_10043488", "reaction_10041950" ] }, "R-BTA-9006931": { "id": "pathway_10093326", "reactome": "R-BTA-9006931", "name": "Signaling by Nuclear Receptors", "reactions": [ "reaction_10090563", "reaction_10091151", "reaction_10090571", "reaction_10090452", "reaction_10071397", "reaction_10071407", "reaction_10090456", "reaction_10042860", "reaction_10091275", "reaction_10072397", "reaction_10091158", "reaction_10090567", "reaction_10091115", "reaction_10089761", "reaction_10090559", "reaction_10091156", "reaction_10072433", "reaction_10071659", "reaction_10072630", "reaction_10076840", "reaction_10091271", "reaction_10072628", "reaction_10072225", "reaction_10090712", "reaction_10071648", "reaction_10071668", "reaction_10091260", "reaction_10071678", "reaction_10044211", "reaction_10086662", "reaction_10071691", "reaction_10091118", "reaction_10092314", "reaction_10091267", "reaction_10090555", "reaction_10071673" ] }, "R-BTA-111931": { "id": "pathway_10092804", "reactome": "R-BTA-111931", "name": "PKA-mediated phosphorylation of CREB", "reactions": [ "reaction_10037004" ] }, "R-BTA-1299316": { "id": "pathway_10094056", "reactome": "R-BTA-1299316", "name": "TWIK-releated acid-sensitive K+ channel (TASK)", "reactions": [ "reaction_10057656" ] }, "R-BTA-9018677": { "id": "pathway_10094912", "reactome": "R-BTA-9018677", "name": "Biosynthesis of DHA-derived SPMs", "reactions": [ "reaction_10090491", "reaction_10090498", "reaction_10090480", "reaction_10090489", "reaction_10090386", "reaction_10090390", "reaction_10090458", "reaction_10090460", "reaction_10090708", "reaction_10090388", "reaction_10090394", "reaction_10090384", "reaction_10090392", "reaction_10090464", "reaction_10090462" ] }, "R-BTA-71240": { "id": "pathway_10092542", "reactome": "R-BTA-71240", "name": "Tryptophan catabolism", "reactions": [ "reaction_10052027", "reaction_10052030", "reaction_10033988", "reaction_10085381", "reaction_10033979", "reaction_10052043", "reaction_10041894", "reaction_10033969" ] }, "R-BTA-8951671": { "id": "pathway_10094842", "reactome": "R-BTA-8951671", "name": "RUNX3 regulates YAP1-mediated transcription", "reactions": [ "reaction_10087862" ] }, "R-BTA-1650814": { "id": "pathway_10094128", "reactome": "R-BTA-1650814", "name": "Collagen biosynthesis and modifying enzymes", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10062071", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10087626", "reaction_10060191", "reaction_10060187", "reaction_10062377", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10064337", "reaction_10061787", "reaction_10087567", "reaction_10087569", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10087579" ] }, "R-BTA-9013406": { "id": "pathway_10094900", "reactome": "R-BTA-9013406", "name": "RHOQ GTPase cycle", "reactions": [ "reaction_10090246", "reaction_10090369", "reaction_10090266" ] }, "R-BTA-9025106": { "id": "pathway_10094926", "reactome": "R-BTA-9025106", "name": "Biosynthesis of DPAn-6 SPMs", "reactions": [ "reaction_10090466", "reaction_10090468" ] }, "R-BTA-390696": { "id": "pathway_10093606", "reactome": "R-BTA-390696", "name": "Adrenoceptors", "reactions": [ "reaction_10047206", "reaction_10047212", "reaction_10090960", "reaction_10090968", "reaction_10090925", "reaction_10090964" ] }, "R-BTA-2142770": { "id": "pathway_10094250", "reactome": "R-BTA-2142770", "name": "Synthesis of 15-eicosatetraenoic acid derivatives", "reactions": [ "reaction_10064546", "reaction_10064578" ] }, "R-BTA-2142700": { "id": "pathway_10094238", "reactome": "R-BTA-2142700", "name": "Synthesis of Lipoxins (LX)", "reactions": [ "reaction_10064500", "reaction_10064491" ] }, "R-BTA-176974": { "id": "pathway_10093128", "reactome": "R-BTA-176974", "name": "Unwinding of DNA", "reactions": [ "reaction_10040183" ] }, "R-BTA-6804116": { "id": "pathway_10094854", "reactome": "R-BTA-6804116", "name": "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest", "reactions": [ "reaction_10088546", "reaction_10088542", "reaction_10088534" ] }, "R-BTA-5663213": { "id": "pathway_10094204", "reactome": "R-BTA-5663213", "name": "RHO GTPases Activate WASPs and WAVEs", "reactions": [ "reaction_10063374" ] }, "R-BTA-181431": { "id": "pathway_10093844", "reactome": "R-BTA-181431", "name": "Acetylcholine binding and downstream events", "reactions": [ "reaction_10051498", "reaction_10051523", "reaction_10051521", "reaction_10051525" ] }, "R-BTA-2046106": { "id": "pathway_10094220", "reactome": "R-BTA-2046106", "name": "alpha-linolenic acid (ALA) metabolism", "reactions": [ "reaction_10063440", "reaction_10063430", "reaction_10063456", "reaction_10063570", "reaction_10063428", "reaction_10063437", "reaction_10063420", "reaction_10063425", "reaction_10063573" ] }, "R-BTA-6807070": { "id": "pathway_10094830", "reactome": "R-BTA-6807070", "name": "PTEN Regulation", "reactions": [ "reaction_10087531" ] }, "R-BTA-68827": { "id": "pathway_10092404", "reactome": "R-BTA-68827", "name": "CDT1 association with the CDC6:ORC:origin complex", "reactions": [ "reaction_10033412" ] }, "R-BTA-3000178": { "id": "pathway_10094282", "reactome": "R-BTA-3000178", "name": "ECM proteoglycans", "reactions": [ "reaction_10065691", "reaction_10065300" ] }, "R-BTA-5205685": { "id": "pathway_10094418", "reactome": "R-BTA-5205685", "name": "PINK1-PRKN Mediated Mitophagy", "reactions": [ "reaction_10070259", "reaction_10070218", "reaction_10070261", "reaction_10070265" ] }, "R-BTA-6799198": { "id": "pathway_10094672", "reactome": "R-BTA-6799198", "name": "Complex I biogenesis", "reactions": [ "reaction_10080515", "reaction_10080519", "reaction_10080517", "reaction_10080521" ] }, "R-BTA-2160916": { "id": "pathway_10094230", "reactome": "R-BTA-2160916", "name": "Hyaluronan uptake and degradation", "reactions": [ "reaction_10064597", "reaction_10064595", "reaction_10064355", "reaction_10064593", "reaction_10064393", "reaction_10091291", "reaction_10064391" ] }, "R-BTA-177929": { "id": "pathway_10092740", "reactome": "R-BTA-177929", "name": "Signaling by EGFR", "reactions": [ "reaction_10044472", "reaction_10040286", "reaction_10040317", "reaction_10040393", "reaction_10091705", "reaction_10040289", "reaction_10040299", "reaction_10040229", "reaction_10040258", "reaction_10040451", "reaction_10040323", "reaction_10040462", "reaction_10040432", "reaction_10040310", "reaction_10044470", "reaction_10040326", "reaction_10040386", "reaction_10040328", "reaction_10040303", "reaction_10044465", "reaction_10040447", "reaction_10040277", "reaction_10040460", "reaction_10040421", "reaction_10040254", "reaction_10040458", "reaction_10040267", "reaction_10040453", "reaction_10040369", "reaction_10036616", "reaction_10040331" ] }, "R-BTA-447115": { "id": "pathway_10093784", "reactome": "R-BTA-447115", "name": "Interleukin-12 family signaling", "reactions": [ "reaction_10049970", "reaction_10087663", "reaction_10087787", "reaction_10087671", "reaction_10087789", "reaction_10087766", "reaction_10049928", "reaction_10089321", "reaction_10089333", "reaction_10087650", "reaction_10087732", "reaction_10089329", "reaction_10089331", "reaction_10087780", "reaction_10087795", "reaction_10088498", "reaction_10087793", "reaction_10049946", "reaction_10087697", "reaction_10087783", "reaction_10087763", "reaction_10087726", "reaction_10087774", "reaction_10088519" ] }, "R-BTA-163359": { "id": "pathway_10092978", "reactome": "R-BTA-163359", "name": "Glucagon signaling in metabolic regulation", "reactions": [ "reaction_10038918" ] }, "R-BTA-5620922": { "id": "pathway_10094494", "reactome": "R-BTA-5620922", "name": "BBSome-mediated cargo-targeting to cilium", "reactions": [ "reaction_10072435", "reaction_10072453", "reaction_10072475" ] }, "R-BTA-73893": { "id": "pathway_10092764", "reactome": "R-BTA-73893", "name": "DNA Damage Bypass", "reactions": [ "reaction_10072883", "reaction_10036886", "reaction_10073302", "reaction_10073279", "reaction_10036844", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036853", "reaction_10036879", "reaction_10072876", "reaction_10036869" ] }, "R-BTA-392451": { "id": "pathway_10093358", "reactome": "R-BTA-392451", "name": "G beta:gamma signalling through PI3Kgamma", "reactions": [ "reaction_10047498", "reaction_10043315" ] }, "R-BTA-9013694": { "id": "pathway_10094976", "reactome": "R-BTA-9013694", "name": "Signaling by NOTCH4", "reactions": [ "reaction_10090834" ] }, "R-BTA-8878171": { "id": "pathway_10094814", "reactome": "R-BTA-8878171", "name": "Transcriptional regulation by RUNX1", "reactions": [ "reaction_10086534", "reaction_10088887", "reaction_10086518", "reaction_10086458", "reaction_10086509", "reaction_10086525", "reaction_10086493", "reaction_10086502", "reaction_10088872", "reaction_10088876", "reaction_10086638", "reaction_10086541" ] }, "R-BTA-1474290": { "id": "pathway_10094088", "reactome": "R-BTA-1474290", "name": "Collagen formation", "reactions": [ "reaction_10087587", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10065929", "reaction_10062071", "reaction_10058705", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10064953", "reaction_10087626", "reaction_10060191", "reaction_10060187", "reaction_10062377", "reaction_10064959", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10087589", "reaction_10064337", "reaction_10061787", "reaction_10087567", "reaction_10087569", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10087579" ] }, "R-BTA-351202": { "id": "pathway_10092506", "reactome": "R-BTA-351202", "name": "Metabolism of polyamines", "reactions": [ "reaction_10044794", "reaction_10044835", "reaction_10044784", "reaction_10044851", "reaction_10033778", "reaction_10044801", "reaction_10044844", "reaction_10044837", "reaction_10044776" ] }, "R-BTA-5652227": { "id": "pathway_10094500", "reactome": "R-BTA-5652227", "name": "Fructose biosynthesis", "reactions": [ "reaction_10072825" ] }, "R-BTA-163754": { "id": "pathway_10092990", "reactome": "R-BTA-163754", "name": "Insulin effects increased synthesis of Xylulose-5-Phosphate", "reactions": [] }, "R-BTA-9013106": { "id": "pathway_10094888", "reactome": "R-BTA-9013106", "name": "RHOC GTPase cycle", "reactions": [ "reaction_10089937", "reaction_10092364", "reaction_10089952", "reaction_10089947" ] }, "R-BTA-6803157": { "id": "pathway_10093982", "reactome": "R-BTA-6803157", "name": "Antimicrobial peptides", "reactions": [ "reaction_10082008", "reaction_10058492", "reaction_10081559", "reaction_10081404", "reaction_10078759", "reaction_10083106", "reaction_10081385", "reaction_10081406", "reaction_10081410", "reaction_10082967", "reaction_10084683", "reaction_10058486", "reaction_10080844", "reaction_10084706", "reaction_10081943", "reaction_10082183", "reaction_10087601", "reaction_10080831", "reaction_10061657", "reaction_10084686", "reaction_10056539", "reaction_10058456", "reaction_10082977", "reaction_10081432", "reaction_10083100", "reaction_10082004", "reaction_10081397", "reaction_10080842", "reaction_10070906", "reaction_10056416", "reaction_10058388", "reaction_10082012" ] }, "R-BTA-1296025": { "id": "pathway_10094024", "reactome": "R-BTA-1296025", "name": "ATP sensitive Potassium channels", "reactions": [ "reaction_10057350" ] }, "R-BTA-8978934": { "id": "pathway_10093586", "reactome": "R-BTA-8978934", "name": "Metabolism of cofactors", "reactions": [ "reaction_10058511", "reaction_10058785", "reaction_10064591", "reaction_10058524", "reaction_10058514", "reaction_10046968" ] }, "R-BTA-1660499": { "id": "pathway_10094142", "reactome": "R-BTA-1660499", "name": "Synthesis of PIPs at the plasma membrane", "reactions": [ "reaction_10060550", "reaction_10082147", "reaction_10060473", "reaction_10085697", "reaction_10082136", "reaction_10060572", "reaction_10060514", "reaction_10082152", "reaction_10085784", "reaction_10060535", "reaction_10060569", "reaction_10085780", "reaction_10060600", "reaction_10060595", "reaction_10060590", "reaction_10060579", "reaction_10060556", "reaction_10085775", "reaction_10060448", "reaction_10060429", "reaction_10060461", "reaction_10082155" ] }, "R-BTA-9634638": { "id": "pathway_10094996", "reactome": "R-BTA-9634638", "name": "Estrogen-dependent nuclear events downstream of ESR-membrane signaling", "reactions": [ "reaction_10091267", "reaction_10091118" ] }, "R-BTA-75815": { "id": "pathway_10092664", "reactome": "R-BTA-75815", "name": "Ubiquitin-dependent degradation of Cyclin D", "reactions": [ "reaction_10035745", "reaction_10035747" ] }, "R-BTA-1295596": { "id": "pathway_10093904", "reactome": "R-BTA-1295596", "name": "Spry regulation of FGF signaling", "reactions": [ "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-74259": { "id": "pathway_10092636", "reactome": "R-BTA-74259", "name": "Purine catabolism", "reactions": [ "reaction_10035464", "reaction_10065359", "reaction_10065763", "reaction_10035455", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10065381", "reaction_10088571", "reaction_10036231", "reaction_10036207", "reaction_10065378", "reaction_10065362", "reaction_10065371", "reaction_10036256", "reaction_10065760", "reaction_10035453", "reaction_10065383", "reaction_10036238", "reaction_10065386" ] }, "R-BTA-5633007": { "id": "pathway_10092432", "reactome": "R-BTA-5633007", "name": "Regulation of TP53 Activity", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10082931", "reaction_10066870", "reaction_10081877", "reaction_10078731", "reaction_10033535", "reaction_10080730", "reaction_10081629", "reaction_10083072", "reaction_10082923", "reaction_10081541", "reaction_10066764", "reaction_10081522", "reaction_10080797", "reaction_10066704", "reaction_10082934", "reaction_10066684", "reaction_10072550", "reaction_10081470", "reaction_10081563", "reaction_10081602", "reaction_10066724", "reaction_10066670", "reaction_10066737", "reaction_10083092", "reaction_10086155", "reaction_10076341", "reaction_10081530", "reaction_10083077", "reaction_10078408", "reaction_10078720", "reaction_10081595", "reaction_10066712", "reaction_10081889", "reaction_10081622", "reaction_10080811", "reaction_10081561" ] }, "R-BTA-446343": { "id": "pathway_10093780", "reactome": "R-BTA-446343", "name": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions", "reactions": [ "reaction_10049883" ] }, "R-BTA-1480926": { "id": "pathway_10094004", "reactome": "R-BTA-1480926", "name": "O2/CO2 exchange in erythrocytes", "reactions": [ "reaction_10058790", "reaction_10057007", "reaction_10081968", "reaction_10058792", "reaction_10057062", "reaction_10057070" ] }, "R-BTA-5669034": { "id": "pathway_10094562", "reactome": "R-BTA-5669034", "name": "TNFs bind their physiological receptors", "reactions": [ "reaction_10073765", "reaction_10076237", "reaction_10076165", "reaction_10074280", "reaction_10074266", "reaction_10074340" ] }, "R-BTA-927802": { "id": "pathway_10093894", "reactome": "R-BTA-927802", "name": "Nonsense-Mediated Decay (NMD)", "reactions": [ "reaction_10052963", "reaction_10053044" ] }, "R-BTA-8964616": { "id": "pathway_10094860", "reactome": "R-BTA-8964616", "name": "G beta:gamma signalling through CDC42", "reactions": [ "reaction_10088962" ] }, "R-BTA-264642": { "id": "pathway_10093454", "reactome": "R-BTA-264642", "name": "Acetylcholine Neurotransmitter Release Cycle", "reactions": [ "reaction_10044540", "reaction_10049090" ] }, "R-BTA-77111": { "id": "pathway_10092608", "reactome": "R-BTA-77111", "name": "Synthesis of Ketone Bodies", "reactions": [ "reaction_10035363", "reaction_10035372" ] }, "R-BTA-4839726": { "id": "pathway_10093978", "reactome": "R-BTA-4839726", "name": "Chromatin organization", "reactions": [ "reaction_10072790", "reaction_10069838", "reaction_10070757", "reaction_10073406", "reaction_10073416", "reaction_10069939", "reaction_10070377", "reaction_10069937", "reaction_10070516", "reaction_10072725", "reaction_10073382", "reaction_10067596", "reaction_10072655", "reaction_10070392", "reaction_10070896", "reaction_10069796", "reaction_10056383", "reaction_10073384", "reaction_10070409", "reaction_10072755", "reaction_10068569", "reaction_10073396", "reaction_10072788", "reaction_10073380", "reaction_10069719", "reaction_10069754", "reaction_10071886", "reaction_10069769", "reaction_10069747", "reaction_10073394", "reaction_10068725", "reaction_10072752", "reaction_10073404", "reaction_10066651", "reaction_10069740", "reaction_10072750", "reaction_10072778", "reaction_10066966", "reaction_10070520", "reaction_10070962", "reaction_10073402", "reaction_10069846", "reaction_10070282", "reaction_10073400", "reaction_10068699", "reaction_10072823", "reaction_10085017", "reaction_10072813", "reaction_10091745", "reaction_10068844" ] }, "R-BTA-6804757": { "id": "pathway_10094332", "reactome": "R-BTA-6804757", "name": "Regulation of TP53 Degradation", "reactions": [ "reaction_10066684", "reaction_10081541", "reaction_10078408" ] }, "R-BTA-9018679": { "id": "pathway_10094908", "reactome": "R-BTA-9018679", "name": "Biosynthesis of EPA-derived SPMs", "reactions": [ "reaction_10090374", "reaction_10090396", "reaction_10090440", "reaction_10090382", "reaction_10090379", "reaction_10090377" ] }, "R-BTA-168188": { "id": "pathway_10093040", "reactome": "R-BTA-168188", "name": "Toll Like Receptor TLR6:TLR2 Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1300642": { "id": "pathway_10094308", "reactome": "R-BTA-1300642", "name": "Sperm Motility And Taxes", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10065866" ] }, "R-BTA-112313": { "id": "pathway_10092496", "reactome": "R-BTA-112313", "name": "Neurotransmitter uptake and metabolism In glial cells", "reactions": [ "reaction_10033746", "reaction_10044086" ] }, "R-BTA-381070": { "id": "pathway_10093546", "reactome": "R-BTA-381070", "name": "IRE1alpha activates chaperones", "reactions": [ "reaction_10046602", "reaction_10046604" ] }, "R-BTA-180024": { "id": "pathway_10092808", "reactome": "R-BTA-180024", "name": "DARPP-32 events", "reactions": [ "reaction_10037037" ] }, "R-BTA-5654710": { "id": "pathway_10094546", "reactome": "R-BTA-5654710", "name": "PI-3K cascade:FGFR3", "reactions": [ "reaction_10073234" ] }, "R-BTA-211945": { "id": "pathway_10092560", "reactome": "R-BTA-211945", "name": "Phase I - Functionalization of compounds", "reactions": [ "reaction_10044477", "reaction_10044533", "reaction_10077496", "reaction_10086550", "reaction_10041177", "reaction_10075404", "reaction_10076375", "reaction_10043971", "reaction_10041412", "reaction_10044235", "reaction_10041386", "reaction_10035958", "reaction_10044182", "reaction_10044255", "reaction_10037751", "reaction_10086543", "reaction_10034231", "reaction_10034206", "reaction_10044242", "reaction_10044280", "reaction_10041415", "reaction_10044250", "reaction_10044223", "reaction_10044275", "reaction_10044204", "reaction_10035977", "reaction_10077734", "reaction_10041195", "reaction_10035878", "reaction_10044216", "reaction_10076884", "reaction_10044524", "reaction_10044225", "reaction_10044265", "reaction_10035911", "reaction_10037748", "reaction_10041397", "reaction_10044167", "reaction_10038000", "reaction_10071909", "reaction_10044247", "reaction_10034175", "reaction_10086557", "reaction_10034215", "reaction_10044195", "reaction_10077751", "reaction_10035865", "reaction_10044218", "reaction_10043964", "reaction_10041393", "reaction_10041193", "reaction_10044151", "reaction_10044270", "reaction_10076144", "reaction_10041277", "reaction_10086469", "reaction_10044211", "reaction_10044480", "reaction_10044158", "reaction_10076475", "reaction_10041217", "reaction_10041206", "reaction_10076856", "reaction_10044260", "reaction_10044232", "reaction_10044293", "reaction_10076863", "reaction_10035861", "reaction_10050160", "reaction_10041500" ] }, "R-BTA-69236": { "id": "pathway_10093138", "reactome": "R-BTA-69236", "name": "G1 Phase", "reactions": [ "reaction_10056602", "reaction_10056616", "reaction_10087394", "reaction_10087487", "reaction_10057821", "reaction_10057816", "reaction_10087385", "reaction_10040355", "reaction_10087503" ] }, "R-BTA-192456": { "id": "pathway_10093244", "reactome": "R-BTA-192456", "name": "Digestion of dietary lipid", "reactions": [ "reaction_10054375", "reaction_10041241", "reaction_10088973", "reaction_10041239" ] }, "R-BTA-202131": { "id": "pathway_10094628", "reactome": "R-BTA-202131", "name": "Metabolism of nitric oxide: NOS3 activation and regulation", "reactions": [ "reaction_10076274" ] }, "R-BTA-2142845": { "id": "pathway_10094228", "reactome": "R-BTA-2142845", "name": "Hyaluronan metabolism", "reactions": [ "reaction_10064597", "reaction_10064595", "reaction_10064355", "reaction_10064593", "reaction_10064393", "reaction_10091291", "reaction_10064353", "reaction_10064391" ] }, "R-BTA-204174": { "id": "pathway_10094880", "reactome": "R-BTA-204174", "name": "Regulation of pyruvate dehydrogenase (PDH) complex", "reactions": [ "reaction_10089721", "reaction_10089728" ] }, "R-BTA-453274": { "id": "pathway_10093090", "reactome": "R-BTA-453274", "name": "Mitotic G2-G2/M phases", "reactions": [ "reaction_10039612", "reaction_10084043", "reaction_10084051", "reaction_10039614", "reaction_10084102", "reaction_10065938", "reaction_10066489", "reaction_10084090", "reaction_10084216", "reaction_10084214", "reaction_10084047", "reaction_10084206", "reaction_10084096", "reaction_10066487", "reaction_10084028" ] }, "R-BTA-3238698": { "id": "pathway_10094342", "reactome": "R-BTA-3238698", "name": "WNT ligand biogenesis and trafficking", "reactions": [ "reaction_10067128", "reaction_10067124", "reaction_10067202", "reaction_10067200", "reaction_10068839", "reaction_10068837", "reaction_10066994", "reaction_10067204" ] }, "R-BTA-8935690": { "id": "pathway_10093162", "reactome": "R-BTA-8935690", "name": "Digestion", "reactions": [ "reaction_10041239", "reaction_10086435", "reaction_10040866", "reaction_10041241", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10086248", "reaction_10088973", "reaction_10073378", "reaction_10040608", "reaction_10054375", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-5365859": { "id": "pathway_10093438", "reactome": "R-BTA-5365859", "name": "RA biosynthesis pathway", "reactions": [ "reaction_10071659", "reaction_10071648", "reaction_10071668", "reaction_10071678", "reaction_10072397", "reaction_10044211", "reaction_10071691", "reaction_10076840", "reaction_10072433", "reaction_10072225", "reaction_10071673" ] }, "R-BTA-5694530": { "id": "pathway_10094632", "reactome": "R-BTA-5694530", "name": "Cargo concentration in the ER", "reactions": [ "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10076696", "reaction_10076586", "reaction_10076706" ] }, "R-BTA-9008059": { "id": "pathway_10094732", "reactome": "R-BTA-9008059", "name": "Interleukin-37 signaling", "reactions": [ "reaction_10089615", "reaction_10089819", "reaction_10089621", "reaction_10089625", "reaction_10089812", "reaction_10083537", "reaction_10089843" ] }, "R-BTA-1236978": { "id": "pathway_10093992", "reactome": "R-BTA-1236978", "name": "Cross-presentation of soluble exogenous antigens (endosomes)", "reactions": [ "reaction_10056912", "reaction_10056835", "reaction_10056805" ] }, "R-BTA-2990846": { "id": "pathway_10094326", "reactome": "R-BTA-2990846", "name": "SUMOylation", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-8939242": { "id": "pathway_10094818", "reactome": "R-BTA-8939242", "name": "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes", "reactions": [ "reaction_10086638" ] }, "R-BTA-75067": { "id": "pathway_10092720", "reactome": "R-BTA-75067", "name": "Processing of Capped Intronless Pre-mRNA", "reactions": [ "reaction_10036076", "reaction_10036915", "reaction_10036917", "reaction_10036052", "reaction_10036080" ] }, "R-BTA-2032785": { "id": "pathway_10094214", "reactome": "R-BTA-2032785", "name": "YAP1- and WWTR1 (TAZ)-stimulated gene expression", "reactions": [ "reaction_10085761", "reaction_10063390", "reaction_10063400" ] }, "R-BTA-174403": { "id": "pathway_10093114", "reactome": "R-BTA-174403", "name": "Glutathione synthesis and recycling", "reactions": [ "reaction_10039865", "reaction_10057079", "reaction_10077658", "reaction_10087515" ] }, "R-BTA-400206": { "id": "pathway_10093652", "reactome": "R-BTA-400206", "name": "Regulation of lipid metabolism by PPARalpha", "reactions": [ "reaction_10047807" ] }, "R-BTA-217271": { "id": "pathway_10093450", "reactome": "R-BTA-217271", "name": "FMO oxidises nucleophiles", "reactions": [ "reaction_10044524", "reaction_10044533" ] }, "R-BTA-9614085": { "id": "pathway_10094984", "reactome": "R-BTA-9614085", "name": "FOXO-mediated transcription", "reactions": [ "reaction_10091049", "reaction_10091017", "reaction_10091033", "reaction_10091023", "reaction_10091029", "reaction_10091096", "reaction_10091184", "reaction_10091089" ] }, "R-BTA-209560": { "id": "pathway_10093402", "reactome": "R-BTA-209560", "name": "NF-kB is activated and signals survival", "reactions": [ "reaction_10043877" ] }, "R-BTA-5689877": { "id": "pathway_10094612", "reactome": "R-BTA-5689877", "name": "Josephin domain DUBs", "reactions": [ "reaction_10075397", "reaction_10075374" ] }, "R-BTA-390666": { "id": "pathway_10093618", "reactome": "R-BTA-390666", "name": "Serotonin receptors", "reactions": [ "reaction_10091929", "reaction_10047238", "reaction_10047236", "reaction_10047256" ] }, "R-BTA-199977": { "id": "pathway_10093374", "reactome": "R-BTA-199977", "name": "ER to Golgi Anterograde Transport", "reactions": [ "reaction_10083380", "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10076708", "reaction_10076610", "reaction_10076696", "reaction_10076778", "reaction_10076635", "reaction_10076736", "reaction_10082038", "reaction_10076586", "reaction_10076706", "reaction_10082026", "reaction_10082045", "reaction_10083377", "reaction_10076584", "reaction_10076698" ] }, "R-BTA-1852241": { "id": "pathway_10094486", "reactome": "R-BTA-1852241", "name": "Organelle biogenesis and maintenance", "reactions": [ "reaction_10075350", "reaction_10075362", "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072271", "reaction_10072489", "reaction_10072453", "reaction_10087635", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-390522": { "id": "pathway_10093602", "reactome": "R-BTA-390522", "name": "Striated Muscle Contraction", "reactions": [ "reaction_10047200", "reaction_10047198", "reaction_10047186", "reaction_10047196" ] }, "R-BTA-156902": { "id": "pathway_10092908", "reactome": "R-BTA-156902", "name": "Peptide chain elongation", "reactions": [ "reaction_10038107" ] }, "R-BTA-191273": { "id": "pathway_10093218", "reactome": "R-BTA-191273", "name": "Cholesterol biosynthesis", "reactions": [ "reaction_10041486", "reaction_10040904", "reaction_10040913", "reaction_10040881", "reaction_10081990", "reaction_10041484", "reaction_10040933", "reaction_10041728", "reaction_10081988", "reaction_10040892", "reaction_10081986", "reaction_10041493", "reaction_10088019", "reaction_10041671", "reaction_10040895", "reaction_10040924", "reaction_10041477", "reaction_10041502", "reaction_10083496", "reaction_10040922", "reaction_10041664", "reaction_10041500" ] }, "R-BTA-2129379": { "id": "pathway_10094232", "reactome": "R-BTA-2129379", "name": "Molecules associated with elastic fibres", "reactions": [ "reaction_10064435", "reaction_10065336", "reaction_10065435" ] }, "R-BTA-9027276": { "id": "pathway_10094884", "reactome": "R-BTA-9027276", "name": "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)", "reactions": [ "reaction_10090501", "reaction_10090428", "reaction_10089841" ] }, "R-BTA-1482788": { "id": "pathway_10094092", "reactome": "R-BTA-1482788", "name": "Acyl chain remodelling of PC", "reactions": [ "reaction_10058990", "reaction_10059858", "reaction_10058970", "reaction_10059856", "reaction_10058829", "reaction_10085826", "reaction_10058996", "reaction_10058809" ] }, "R-BTA-9707587": { "id": "pathway_10095042", "reactome": "R-BTA-9707587", "name": "Regulation of HMOX1 expression and activity", "reactions": [ "reaction_10092289", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10092239" ] }, "R-BTA-196299": { "id": "pathway_10093274", "reactome": "R-BTA-196299", "name": "Beta-catenin phosphorylation cascade", "reactions": [ "reaction_10041647", "reaction_10041629", "reaction_10041637", "reaction_10041640" ] }, "R-BTA-5617833": { "id": "pathway_10094484", "reactome": "R-BTA-5617833", "name": "Cilium Assembly", "reactions": [ "reaction_10072401", "reaction_10072326", "reaction_10072435", "reaction_10072497", "reaction_10072271", "reaction_10072489", "reaction_10072453", "reaction_10072426", "reaction_10072475" ] }, "R-BTA-1475029": { "id": "pathway_10094090", "reactome": "R-BTA-1475029", "name": "Reversible hydration of carbon dioxide", "reactions": [ "reaction_10058722", "reaction_10058772", "reaction_10058755", "reaction_10058751", "reaction_10058774", "reaction_10058753" ] }, "R-BTA-140534": { "id": "pathway_10092616", "reactome": "R-BTA-140534", "name": "Caspase activation via Death Receptors in the presence of ligand", "reactions": [ "reaction_10068046", "reaction_10035396", "reaction_10068042", "reaction_10037991", "reaction_10037985", "reaction_10067895", "reaction_10067891" ] }, "R-BTA-912526": { "id": "pathway_10093822", "reactome": "R-BTA-912526", "name": "Interleukin receptor SHC signaling", "reactions": [ "reaction_10052343", "reaction_10050623", "reaction_10050619", "reaction_10052254", "reaction_10052337" ] }, "R-BTA-156590": { "id": "pathway_10093116", "reactome": "R-BTA-156590", "name": "Glutathione conjugation", "reactions": [ "reaction_10057079", "reaction_10039865", "reaction_10040021", "reaction_10067425", "reaction_10087515", "reaction_10076133", "reaction_10040030", "reaction_10077658" ] }, "R-BTA-211859": { "id": "pathway_10092562", "reactome": "R-BTA-211859", "name": "Biological oxidations", "reactions": [ "reaction_10071712", "reaction_10039887", "reaction_10038318", "reaction_10071722", "reaction_10038338", "reaction_10044255", "reaction_10035863", "reaction_10040136", "reaction_10044250", "reaction_10076900", "reaction_10038060", "reaction_10035977", "reaction_10076898", "reaction_10040030", "reaction_10071763", "reaction_10035911", "reaction_10071909", "reaction_10040115", "reaction_10034215", "reaction_10038380", "reaction_10087515", "reaction_10038340", "reaction_10039921", "reaction_10038354", "reaction_10086469", "reaction_10041277", "reaction_10044211", "reaction_10044480", "reaction_10038336", "reaction_10040021", "reaction_10044232", "reaction_10076903", "reaction_10041500", "reaction_10071754", "reaction_10044477", "reaction_10071729", "reaction_10038371", "reaction_10041177", "reaction_10071717", "reaction_10043971", "reaction_10077658", "reaction_10039874", "reaction_10044235", "reaction_10041386", "reaction_10044182", "reaction_10086543", "reaction_10038231", "reaction_10034206", "reaction_10044223", "reaction_10041415", "reaction_10044225", "reaction_10038000", "reaction_10039865", "reaction_10039918", "reaction_10040152", "reaction_10044270", "reaction_10041193", "reaction_10067425", "reaction_10041206", "reaction_10076856", "reaction_10044293", "reaction_10050160", "reaction_10040185", "reaction_10077496", "reaction_10075404", "reaction_10041412", "reaction_10037751", "reaction_10034231", "reaction_10040129", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10037748", "reaction_10076884", "reaction_10044265", "reaction_10040157", "reaction_10041397", "reaction_10044167", "reaction_10044247", "reaction_10034175", "reaction_10040112", "reaction_10071924", "reaction_10038382", "reaction_10076799", "reaction_10086557", "reaction_10038238", "reaction_10044195", "reaction_10039930", "reaction_10040107", "reaction_10041393", "reaction_10040098", "reaction_10071715", "reaction_10088617", "reaction_10076475", "reaction_10044158", "reaction_10040117", "reaction_10039916", "reaction_10076785", "reaction_10035861", "reaction_10076863", "reaction_10076133", "reaction_10038316", "reaction_10041195", "reaction_10040147", "reaction_10044533", "reaction_10086550", "reaction_10076375", "reaction_10035958", "reaction_10044242", "reaction_10044204", "reaction_10044275", "reaction_10035878", "reaction_10040131", "reaction_10044216", "reaction_10040122", "reaction_10044524", "reaction_10057079", "reaction_10077751", "reaction_10040120", "reaction_10035865", "reaction_10038320", "reaction_10044218", "reaction_10043964", "reaction_10044151", "reaction_10076144", "reaction_10051570", "reaction_10071727", "reaction_10041217", "reaction_10044260", "reaction_10039923", "reaction_10088580" ] }, "R-BTA-8866654": { "id": "pathway_10094822", "reactome": "R-BTA-8866654", "name": "E3 ubiquitin ligases ubiquitinate target proteins", "reactions": [ "reaction_10086710", "reaction_10086702" ] }, "R-BTA-622323": { "id": "pathway_10093842", "reactome": "R-BTA-622323", "name": "Presynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051498", "reaction_10051525" ] }, "R-BTA-983168": { "id": "pathway_10093944", "reactome": "R-BTA-983168", "name": "Antigen processing: Ubiquitination & Proteasome degradation", "reactions": [ "reaction_10055491", "reaction_10055448", "reaction_10055431", "reaction_10055451", "reaction_10055453" ] }, "R-BTA-5632684": { "id": "pathway_10094478", "reactome": "R-BTA-5632684", "name": "Hedgehog 'on' state", "reactions": [ "reaction_10072606", "reaction_10072720", "reaction_10072677", "reaction_10072715", "reaction_10072685", "reaction_10072081", "reaction_10072713" ] }, "R-BTA-5673000": { "id": "pathway_10094566", "reactome": "R-BTA-5673000", "name": "RAF activation", "reactions": [ "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10073904", "reaction_10074088", "reaction_10073940", "reaction_10073917", "reaction_10073932", "reaction_10073921", "reaction_10091548" ] }, "R-BTA-5628897": { "id": "pathway_10092468", "reactome": "R-BTA-5628897", "name": "TP53 Regulates Metabolic Genes", "reactions": [ "reaction_10033755", "reaction_10072595", "reaction_10034166", "reaction_10072591", "reaction_10072571", "reaction_10033592", "reaction_10072557", "reaction_10072614", "reaction_10046588", "reaction_10038647" ] }, "R-BTA-425393": { "id": "pathway_10093484", "reactome": "R-BTA-425393", "name": "Transport of inorganic cations/anions and amino acids/oligopeptides", "reactions": [ "reaction_10085384", "reaction_10048740", "reaction_10048550", "reaction_10049173", "reaction_10048533", "reaction_10048754", "reaction_10045501", "reaction_10048594", "reaction_10048478", "reaction_10044962", "reaction_10072522", "reaction_10045473", "reaction_10085896", "reaction_10048802", "reaction_10048761", "reaction_10048795", "reaction_10048504", "reaction_10049170", "reaction_10048618", "reaction_10048601", "reaction_10045487", "reaction_10048727", "reaction_10048821", "reaction_10048567", "reaction_10049083", "reaction_10048965", "reaction_10048768", "reaction_10044964", "reaction_10045494", "reaction_10044941", "reaction_10048491", "reaction_10048526", "reaction_10044971", "reaction_10060218", "reaction_10048747", "reaction_10048804", "reaction_10045480", "reaction_10044934", "reaction_10088905", "reaction_10044985", "reaction_10045050", "reaction_10048958", "reaction_10044948", "reaction_10044978", "reaction_10044955", "reaction_10085967" ] }, "R-BTA-5627123": { "id": "pathway_10094202", "reactome": "R-BTA-5627123", "name": "RHO GTPases activate PAKs", "reactions": [ "reaction_10063353" ] }, "R-BTA-111932": { "id": "pathway_10092782", "reactome": "R-BTA-111932", "name": "CaMK IV-mediated phosphorylation of CREB", "reactions": [ "reaction_10049478", "reaction_10036981" ] }, "R-BTA-5674135": { "id": "pathway_10094574", "reactome": "R-BTA-5674135", "name": "MAP2K and MAPK activation", "reactions": [ "reaction_10091570", "reaction_10091576", "reaction_10074129", "reaction_10074137", "reaction_10091572", "reaction_10074176", "reaction_10074195", "reaction_10091568" ] }, "R-BTA-111471": { "id": "pathway_10092822", "reactome": "R-BTA-111471", "name": "Apoptotic factor-mediated response", "reactions": [ "reaction_10037253", "reaction_10091188", "reaction_10037289", "reaction_10091191", "reaction_10037264", "reaction_10037293", "reaction_10091197", "reaction_10081897", "reaction_10091186" ] }, "R-BTA-73933": { "id": "pathway_10094852", "reactome": "R-BTA-73933", "name": "Resolution of Abasic Sites (AP sites)", "reactions": [ "reaction_10088526" ] }, "R-BTA-389359": { "id": "pathway_10093574", "reactome": "R-BTA-389359", "name": "CD28 dependent Vav1 pathway", "reactions": [ "reaction_10046822", "reaction_10046943" ] }, "R-BTA-83936": { "id": "pathway_10092726", "reactome": "R-BTA-83936", "name": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "reactions": [ "reaction_10036297", "reaction_10071001", "reaction_10071003", "reaction_10070991", "reaction_10036274", "reaction_10038660", "reaction_10036283", "reaction_10036276", "reaction_10051545", "reaction_10036290", "reaction_10051547", "reaction_10073838" ] }, "R-BTA-1299344": { "id": "pathway_10094058", "reactome": "R-BTA-1299344", "name": "TWIK-related spinal cord K+ channel (TRESK)", "reactions": [ "reaction_10057665" ] }, "R-BTA-159418": { "id": "pathway_10092926", "reactome": "R-BTA-159418", "name": "Recycling of bile acids and salts", "reactions": [ "reaction_10041437", "reaction_10085806", "reaction_10038347" ] }, "R-BTA-1296052": { "id": "pathway_10094030", "reactome": "R-BTA-1296052", "name": "Ca2+ activated K+ channels", "reactions": [ "reaction_10057365" ] }, "R-BTA-2514859": { "id": "pathway_10092654", "reactome": "R-BTA-2514859", "name": "Inactivation, recovery and regulation of the phototransduction cascade", "reactions": [ "reaction_10035596", "reaction_10065944", "reaction_10065808", "reaction_10035619", "reaction_10077744", "reaction_10065940" ] }, "R-BTA-159424": { "id": "pathway_10092934", "reactome": "R-BTA-159424", "name": "Conjugation of carboxylic acids", "reactions": [ "reaction_10038382", "reaction_10038380", "reaction_10038371", "reaction_10038354", "reaction_10040185" ] }, "R-BTA-1187000": { "id": "pathway_10094048", "reactome": "R-BTA-1187000", "name": "Fertilization", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10057605", "reaction_10057598", "reaction_10065827", "reaction_10065866" ] }, "R-BTA-8849470": { "id": "pathway_10094734", "reactome": "R-BTA-8849470", "name": "PTK6 Regulates Cell Cycle", "reactions": [ "reaction_10083565", "reaction_10083558" ] }, "R-BTA-168928": { "id": "pathway_10093902", "reactome": "R-BTA-168928", "name": "DDX58/IFIH1-mediated induction of interferon-alpha/beta", "reactions": [ "reaction_10056090", "reaction_10053134", "reaction_10053046", "reaction_10056084", "reaction_10053095", "reaction_10092318", "reaction_10053058", "reaction_10053048", "reaction_10056082", "reaction_10056088", "reaction_10053122" ] }, "R-BTA-425410": { "id": "pathway_10093758", "reactome": "R-BTA-425410", "name": "Metal ion SLC transporters", "reactions": [ "reaction_10049371", "reaction_10049392", "reaction_10049402", "reaction_10049378", "reaction_10049440", "reaction_10049385", "reaction_10088912", "reaction_10049464", "reaction_10049447", "reaction_10049433" ] }, "R-BTA-139853": { "id": "pathway_10092848", "reactome": "R-BTA-139853", "name": "Elevation of cytosolic Ca2+ levels", "reactions": [ "reaction_10048635", "reaction_10037607" ] }, "R-BTA-4085001": { "id": "pathway_10093730", "reactome": "R-BTA-4085001", "name": "Sialic acid metabolism", "reactions": [ "reaction_10069373", "reaction_10069382", "reaction_10069329", "reaction_10069346", "reaction_10069371", "reaction_10051554", "reaction_10069348", "reaction_10069368", "reaction_10048958", "reaction_10069320", "reaction_10069359", "reaction_10069357" ] }, "R-BTA-5693606": { "id": "pathway_10092658", "reactome": "R-BTA-5693606", "name": "DNA Double Strand Break Response", "reactions": [ "reaction_10076334", "reaction_10076298", "reaction_10074550", "reaction_10074670", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10074720", "reaction_10035720", "reaction_10074747", "reaction_10076303", "reaction_10074677", "reaction_10074695", "reaction_10035712", "reaction_10076329", "reaction_10076341", "reaction_10076343", "reaction_10074453", "reaction_10074692", "reaction_10076332", "reaction_10074759", "reaction_10074736", "reaction_10068854", "reaction_10074761", "reaction_10074679", "reaction_10075173" ] }, "R-BTA-8936459": { "id": "pathway_10094812", "reactome": "R-BTA-8936459", "name": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "reactions": [ "reaction_10086534", "reaction_10086518", "reaction_10086458", "reaction_10086525", "reaction_10086509", "reaction_10086493", "reaction_10086502", "reaction_10086541" ] }, "R-BTA-9025094": { "id": "pathway_10094932", "reactome": "R-BTA-9025094", "name": "Biosynthesis of DPAn-3 SPMs", "reactions": [ "reaction_10090472", "reaction_10090477", "reaction_10090474", "reaction_10090470" ] }, "R-BTA-9020702": { "id": "pathway_10093398", "reactome": "R-BTA-9020702", "name": "Interleukin-1 signaling", "reactions": [ "reaction_10091757", "reaction_10049721", "reaction_10050428", "reaction_10051095", "reaction_10043867", "reaction_10050420" ] }, "R-BTA-168256": { "id": "pathway_10093006", "reactome": "R-BTA-168256", "name": "Immune System", "reactions": [ "reaction_10051936", "reaction_10065009", "reaction_10043302", "reaction_10050196", "reaction_10066551", "reaction_10056268", "reaction_10089466", "reaction_10054791", "reaction_10072364", "reaction_10065051", "reaction_10092165", "reaction_10063374", "reaction_10077921", "reaction_10066141", "reaction_10077790", "reaction_10051966", "reaction_10072045", "reaction_10065413", "reaction_10073690", "reaction_10051786", "reaction_10089329", "reaction_10092257", "reaction_10092043", "reaction_10039217", "reaction_10061502", "reaction_10077843", "reaction_10080842", "reaction_10089480", "reaction_10086405", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10055491", "reaction_10056084", "reaction_10087787", "reaction_10089341", "reaction_10081385", "reaction_10087671", "reaction_10082967", "reaction_10060783", "reaction_10055958", "reaction_10089321", "reaction_10089516", "reaction_10084658", "reaction_10089333", "reaction_10073757", "reaction_10089536", "reaction_10055453", "reaction_10050254", "reaction_10052343", "reaction_10072383", "reaction_10089523", "reaction_10087774", "reaction_10089530", "reaction_10046903", "reaction_10065011", "reaction_10058492", "reaction_10081404", "reaction_10091723", "reaction_10074312", "reaction_10089591", "reaction_10056178", "reaction_10084683", "reaction_10056912", "reaction_10089311", "reaction_10055955", "reaction_10056199", "reaction_10081943", "reaction_10091743", "reaction_10050256", "reaction_10067225", "reaction_10084636", "reaction_10089453", "reaction_10089689", "reaction_10054649", "reaction_10055971", "reaction_10079391", "reaction_10065642", "reaction_10074993", "reaction_10060773", "reaction_10056914", "reaction_10081905", "reaction_10089349", "reaction_10056132", "reaction_10053122", "reaction_10072053", "reaction_10051771", "reaction_10089511", "reaction_10043193", "reaction_10077926", "reaction_10065491", "reaction_10052229", "reaction_10082008", "reaction_10050623", "reaction_10056315", "reaction_10089542", "reaction_10066880", "reaction_10056335", "reaction_10053095", "reaction_10050428", "reaction_10060412", "reaction_10056283", "reaction_10089736", "reaction_10089269", "reaction_10084322", "reaction_10089597", "reaction_10089331", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10089812", "reaction_10066168", "reaction_10077870", "reaction_10050619", "reaction_10055819", "reaction_10066532", "reaction_10063376", "reaction_10078759", "reaction_10051696", "reaction_10066536", "reaction_10046932", "reaction_10055448", "reaction_10067223", "reaction_10050231", "reaction_10042826", "reaction_10065402", "reaction_10046909", "reaction_10063353", "reaction_10042129", "reaction_10090919", "reaction_10090400", "reaction_10090844", "reaction_10083100", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10067233", "reaction_10072057", "reaction_10064219", "reaction_10082012", "reaction_10052217", "reaction_10051196", "reaction_10052325", "reaction_10057004", "reaction_10089267", "reaction_10039465", "reaction_10089625", "reaction_10079199", "reaction_10056910", "reaction_10092126", "reaction_10051737", "reaction_10089431", "reaction_10061657", "reaction_10056172", "reaction_10087780", "reaction_10075923", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10090031", "reaction_10056287", "reaction_10052210", "reaction_10057834", "reaction_10080063", "reaction_10089819", "reaction_10091747", "reaction_10077924", "reaction_10041950", "reaction_10066127", "reaction_10054779", "reaction_10039778", "reaction_10072002", "reaction_10089538", "reaction_10066059", "reaction_10064068", "reaction_10081406", "reaction_10084867", "reaction_10051818", "reaction_10052735", "reaction_10066052", "reaction_10089446", "reaction_10066147", "reaction_10089444", "reaction_10090916", "reaction_10092195", "reaction_10043867", "reaction_10074899", "reaction_10055431", "reaction_10077723", "reaction_10056539", "reaction_10081432", "reaction_10055817", "reaction_10092183", "reaction_10089621", "reaction_10084020", "reaction_10092151", "reaction_10072006", "reaction_10041863", "reaction_10092147", "reaction_10050028", "reaction_10076165", "reaction_10056835", "reaction_10050527", "reaction_10087766", "reaction_10047907", "reaction_10083522", "reaction_10082183", "reaction_10051792", "reaction_10056082", "reaction_10084672", "reaction_10050420", "reaction_10087650", "reaction_10042786", "reaction_10052327", "reaction_10065388", "reaction_10076237", "reaction_10089427", "reaction_10074306", "reaction_10092141", "reaction_10043241", "reaction_10052240", "reaction_10092137", "reaction_10046834", "reaction_10056102", "reaction_10049721", "reaction_10087797", "reaction_10046951", "reaction_10077764", "reaction_10084865", "reaction_10089363", "reaction_10081085", "reaction_10056297", "reaction_10077904", "reaction_10072395", "reaction_10056127", "reaction_10052321", "reaction_10066144", "reaction_10074266", "reaction_10066102", "reaction_10055821", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10080844", "reaction_10043300", "reaction_10089691", "reaction_10072388", "reaction_10056088", "reaction_10070719", "reaction_10052196", "reaction_10050011", "reaction_10080435", "reaction_10042253", "reaction_10081397", "reaction_10087783", "reaction_10087763", "reaction_10056416", "reaction_10051774", "reaction_10043659", "reaction_10049970", "reaction_10065055", "reaction_10083537", "reaction_10087823", "reaction_10043274", "reaction_10089843", "reaction_10063972", "reaction_10047530", "reaction_10077945", "reaction_10053058", "reaction_10079949", "reaction_10077422", "reaction_10071975", "reaction_10074340", "reaction_10091757", "reaction_10065227", "reaction_10042623", "reaction_10087795", "reaction_10089251", "reaction_10046787", "reaction_10049946", "reaction_10051962", "reaction_10091731", "reaction_10070906", "reaction_10074901", "reaction_10072374", "reaction_10066180", "reaction_10066151", "reaction_10056130", "reaction_10081559", "reaction_10043304", "reaction_10067229", "reaction_10090027", "reaction_10072061", "reaction_10043270", "reaction_10058486", "reaction_10078929", "reaction_10077633", "reaction_10055451", "reaction_10043244", "reaction_10074318", "reaction_10056982", "reaction_10080831", "reaction_10066172", "reaction_10080719", "reaction_10065019", "reaction_10052147", "reaction_10092318", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10087663", "reaction_10092033", "reaction_10050208", "reaction_10052471", "reaction_10060730", "reaction_10060759", "reaction_10039508", "reaction_10077919", "reaction_10046822", "reaction_10052233", "reaction_10056090", "reaction_10052189", "reaction_10052466", "reaction_10045016", "reaction_10058456", "reaction_10089595", "reaction_10066608", "reaction_10081506", "reaction_10087726", "reaction_10092040", "reaction_10057836", "reaction_10064277", "reaction_10050024", "reaction_10088519", "reaction_10075009", "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10052213", "reaction_10051762", "reaction_10052254", "reaction_10056531", "reaction_10053134", "reaction_10089506", "reaction_10053213", "reaction_10056205", "reaction_10089442", "reaction_10046807", "reaction_10066094", "reaction_10046888", "reaction_10083967", "reaction_10081265", "reaction_10081510", "reaction_10051836", "reaction_10043262", "reaction_10043212", "reaction_10065407", "reaction_10056805", "reaction_10053048", "reaction_10074280", "reaction_10074314", "reaction_10072011", "reaction_10092108", "reaction_10055783", "reaction_10089291", "reaction_10083106", "reaction_10040197", "reaction_10087789", "reaction_10085369", "reaction_10089615", "reaction_10092139", "reaction_10056170", "reaction_10054678", "reaction_10056110", "reaction_10071982", "reaction_10089540", "reaction_10043219", "reaction_10087732", "reaction_10050218", "reaction_10051095", "reaction_10052067", "reaction_10083959", "reaction_10043182", "reaction_10065517", "reaction_10066082", "reaction_10055444", "reaction_10060785", "reaction_10089253", "reaction_10065894", "reaction_10084706", "reaction_10050192", "reaction_10043298", "reaction_10056188", "reaction_10066238", "reaction_10092173", "reaction_10077455", "reaction_10081410", "reaction_10066080", "reaction_10056239", "reaction_10089455", "reaction_10046959", "reaction_10064214", "reaction_10079653", "reaction_10057823", "reaction_10056289", "reaction_10064221", "reaction_10056194", "reaction_10055946", "reaction_10066120", "reaction_10055967", "reaction_10056176", "reaction_10061174", "reaction_10074320", "reaction_10052236", "reaction_10056903", "reaction_10060694", "reaction_10076963", "reaction_10082977", "reaction_10051780", "reaction_10084305", "reaction_10065021", "reaction_10051748", "reaction_10073765", "reaction_10082004", "reaction_10050054", "reaction_10090019", "reaction_10087338", "reaction_10043252", "reaction_10087807", "reaction_10058388", "reaction_10091725", "reaction_10055460", "reaction_10056207", "reaction_10046907", "reaction_10046943", "reaction_10066559", "reaction_10039782", "reaction_10056123", "reaction_10052323", "reaction_10047519", "reaction_10039481", "reaction_10089703", "reaction_10054736", "reaction_10091817", "reaction_10054866", "reaction_10049928", "reaction_10073708", "reaction_10071948", "reaction_10067231", "reaction_10089696", "reaction_10052159", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10063368", "reaction_10092143", "reaction_10051949", "reaction_10092159", "reaction_10074308", "reaction_10088498", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074310", "reaction_10084401", "reaction_10049983", "reaction_10042635", "reaction_10054524", "reaction_10064118", "reaction_10053046", "reaction_10047536", "reaction_10085017", "reaction_10051954", "reaction_10072392", "reaction_10046811", "reaction_10052302" ] }, "R-BTA-429914": { "id": "pathway_10093742", "reactome": "R-BTA-429914", "name": "Deadenylation-dependent mRNA decay", "reactions": [ "reaction_10049230", "reaction_10049232" ] }, "R-BTA-1855231": { "id": "pathway_10094176", "reactome": "R-BTA-1855231", "name": "Synthesis of IPs in the ER lumen", "reactions": [ "reaction_10060963", "reaction_10061122", "reaction_10061043" ] }, "R-BTA-5676594": { "id": "pathway_10094560", "reactome": "R-BTA-5676594", "name": "TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway", "reactions": [ "reaction_10073757", "reaction_10074308", "reaction_10074320", "reaction_10074316", "reaction_10074306", "reaction_10074318", "reaction_10074314", "reaction_10074310", "reaction_10074312" ] }, "R-BTA-73817": { "id": "pathway_10092606", "reactome": "R-BTA-73817", "name": "Purine ribonucleoside monophosphate biosynthesis", "reactions": [ "reaction_10035332", "reaction_10035354", "reaction_10035339", "reaction_10036907", "reaction_10036928", "reaction_10036909", "reaction_10035308", "reaction_10091727", "reaction_10035345", "reaction_10035342", "reaction_10035329", "reaction_10035319" ] }, "R-BTA-5693571": { "id": "pathway_10094604", "reactome": "R-BTA-5693571", "name": "Nonhomologous End-Joining (NHEJ)", "reactions": [ "reaction_10076347", "reaction_10076327", "reaction_10075295", "reaction_10076312", "reaction_10076286" ] }, "R-BTA-5688426": { "id": "pathway_10094374", "reactome": "R-BTA-5688426", "name": "Deubiquitination", "reactions": [ "reaction_10075808", "reaction_10075550", "reaction_10077363", "reaction_10085345", "reaction_10075942", "reaction_10084931", "reaction_10077393", "reaction_10077034", "reaction_10075989", "reaction_10075970", "reaction_10077292", "reaction_10077371", "reaction_10076001", "reaction_10075891", "reaction_10077070", "reaction_10076119", "reaction_10077331", "reaction_10075902", "reaction_10075397", "reaction_10075374", "reaction_10075952", "reaction_10077349", "reaction_10076112", "reaction_10068095", "reaction_10077406", "reaction_10075984", "reaction_10077339", "reaction_10075561", "reaction_10077317", "reaction_10077379" ] }, "R-BTA-9018519": { "id": "pathway_10094882", "reactome": "R-BTA-9018519", "name": "Estrogen-dependent gene expression", "reactions": [ "reaction_10089761" ] }, "R-BTA-9711097": { "id": "pathway_10095010", "reactome": "R-BTA-9711097", "name": "Cellular response to starvation", "reactions": [ "reaction_10091354", "reaction_10091356", "reaction_10091336", "reaction_10091365", "reaction_10091351", "reaction_10091401", "reaction_10091404" ] }, "R-BTA-2995383": { "id": "pathway_10094998", "reactome": "R-BTA-2995383", "name": "Initiation of Nuclear Envelope (NE) Reformation", "reactions": [ "reaction_10091132" ] }, "R-BTA-3215018": { "id": "pathway_10094324", "reactome": "R-BTA-3215018", "name": "Processing and activation of SUMO", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-73614": { "id": "pathway_10092594", "reactome": "R-BTA-73614", "name": "Pyrimidine salvage", "reactions": [ "reaction_10088624", "reaction_10035020", "reaction_10034989", "reaction_10036649", "reaction_10034980", "reaction_10035479", "reaction_10036614", "reaction_10035007" ] }, "R-BTA-5696398": { "id": "pathway_10092746", "reactome": "R-BTA-5696398", "name": "Nucleotide Excision Repair", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10077016", "reaction_10076071", "reaction_10076009", "reaction_10036661" ] }, "R-BTA-201688": { "id": "pathway_10094378", "reactome": "R-BTA-201688", "name": "WNT mediated activation of DVL", "reactions": [ "reaction_10068707", "reaction_10068704" ] }, "R-BTA-8864260": { "id": "pathway_10093536", "reactome": "R-BTA-8864260", "name": "Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors", "reactions": [ "reaction_10084911", "reaction_10084935", "reaction_10084881", "reaction_10084922", "reaction_10084909", "reaction_10045744", "reaction_10084903", "reaction_10084895" ] }, "R-BTA-2029482": { "id": "pathway_10094200", "reactome": "R-BTA-2029482", "name": "Regulation of actin dynamics for phagocytic cup formation", "reactions": [ "reaction_10063374", "reaction_10063353" ] }, "R-BTA-111463": { "id": "pathway_10092830", "reactome": "R-BTA-111463", "name": "SMAC (DIABLO) binds to IAPs ", "reactions": [ "reaction_10091191", "reaction_10037289" ] }, "R-BTA-8956320": { "id": "pathway_10092586", "reactome": "R-BTA-8956320", "name": "Nucleobase biosynthesis", "reactions": [ "reaction_10034927", "reaction_10035342", "reaction_10035332", "reaction_10034921", "reaction_10035354", "reaction_10035339", "reaction_10036907", "reaction_10036928", "reaction_10036909", "reaction_10035308", "reaction_10091727", "reaction_10035345", "reaction_10034924", "reaction_10035329", "reaction_10035319" ] }, "R-BTA-5693548": { "id": "pathway_10092656", "reactome": "R-BTA-5693548", "name": "Sensing of DNA Double Strand Breaks", "reactions": [ "reaction_10035720", "reaction_10068854", "reaction_10035712", "reaction_10076298", "reaction_10076343", "reaction_10074453", "reaction_10074761", "reaction_10074759" ] }, "R-BTA-435368": { "id": "pathway_10093760", "reactome": "R-BTA-435368", "name": "Zinc efflux and compartmentalization by the SLC30 family", "reactions": [ "reaction_10049385", "reaction_10049392", "reaction_10049378" ] }, "R-BTA-1483226": { "id": "pathway_10094110", "reactome": "R-BTA-1483226", "name": "Synthesis of PI", "reactions": [ "reaction_10085340", "reaction_10059091", "reaction_10059044" ] }, "R-BTA-444257": { "id": "pathway_10094948", "reactome": "R-BTA-444257", "name": "RSK activation", "reactions": [ "reaction_10090547" ] }, "R-BTA-73928": { "id": "pathway_10092750", "reactome": "R-BTA-73928", "name": "Depyrimidination", "reactions": [ "reaction_10036716", "reaction_10036767", "reaction_10036709", "reaction_10036729", "reaction_10036736", "reaction_10036743" ] }, "R-BTA-2730905": { "id": "pathway_10093352", "reactome": "R-BTA-2730905", "name": "Role of LAT2/NTAL/LAB on calcium mobilization", "reactions": [ "reaction_10066144", "reaction_10043182", "reaction_10066080" ] }, "R-BTA-3000157": { "id": "pathway_10093448", "reactome": "R-BTA-3000157", "name": "Laminin interactions", "reactions": [ "reaction_10069313", "reaction_10044515", "reaction_10065555" ] }, "R-BTA-983712": { "id": "pathway_10093672", "reactome": "R-BTA-983712", "name": "Ion channel transport", "reactions": [ "reaction_10091583", "reaction_10066232", "reaction_10076179", "reaction_10067346", "reaction_10091542", "reaction_10071254", "reaction_10066282", "reaction_10092050", "reaction_10066270", "reaction_10066227", "reaction_10066004", "reaction_10047893", "reaction_10076172", "reaction_10053143", "reaction_10048787", "reaction_10066199", "reaction_10053258", "reaction_10066034", "reaction_10066021", "reaction_10053180", "reaction_10084767", "reaction_10053210", "reaction_10047900", "reaction_10066289", "reaction_10067332", "reaction_10065965", "reaction_10066277", "reaction_10065991", "reaction_10091759", "reaction_10066206" ] }, "R-BTA-9706374": { "id": "pathway_10095036", "reactome": "R-BTA-9706374", "name": "FLT3 signaling through SRC family kinases", "reactions": [ "reaction_10092151" ] }, "R-BTA-2022870": { "id": "pathway_10094192", "reactome": "R-BTA-2022870", "name": "Chondroitin sulfate biosynthesis", "reactions": [ "reaction_10061642", "reaction_10062463", "reaction_10061651", "reaction_10063014", "reaction_10061612" ] }, "R-BTA-203615": { "id": "pathway_10094626", "reactome": "R-BTA-203615", "name": "eNOS activation", "reactions": [ "reaction_10076274" ] }, "R-BTA-9640463": { "id": "pathway_10093598", "reactome": "R-BTA-9640463", "name": "Wax biosynthesis", "reactions": [ "reaction_10047065", "reaction_10077001", "reaction_10083575", "reaction_10083577" ] }, "R-BTA-5696394": { "id": "pathway_10094622", "reactome": "R-BTA-5696394", "name": "DNA Damage Recognition in GG-NER", "reactions": [ "reaction_10077396", "reaction_10077108", "reaction_10076009", "reaction_10076071" ] }, "R-BTA-5625900": { "id": "pathway_10094564", "reactome": "R-BTA-5625900", "name": "RHO GTPases activate CIT", "reactions": [ "reaction_10073796", "reaction_10073806" ] }, "R-BTA-111465": { "id": "pathway_10093340", "reactome": "R-BTA-111465", "name": "Apoptotic cleavage of cellular proteins", "reactions": [ "reaction_10044756", "reaction_10044762", "reaction_10044995", "reaction_10044568", "reaction_10044896", "reaction_10090575", "reaction_10043049", "reaction_10043059", "reaction_10044578", "reaction_10043021", "reaction_10090573", "reaction_10044906", "reaction_10044923", "reaction_10043039" ] }, "R-BTA-2559585": { "id": "pathway_10093140", "reactome": "R-BTA-2559585", "name": "Oncogene Induced Senescence", "reactions": [ "reaction_10066630", "reaction_10040355" ] }, "R-BTA-9012999": { "id": "pathway_10094864", "reactome": "R-BTA-9012999", "name": "RHO GTPase cycle", "reactions": [ "reaction_10089937", "reaction_10090330", "reaction_10090145", "reaction_10090306", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10090087", "reaction_10089888", "reaction_10090119", "reaction_10090103", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10090082", "reaction_10090125", "reaction_10090339", "reaction_10090089", "reaction_10091994", "reaction_10091921", "reaction_10089972", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10089930", "reaction_10090349", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10091884", "reaction_10090198", "reaction_10089947", "reaction_10092392", "reaction_10090077", "reaction_10091896", "reaction_10092382", "reaction_10092022", "reaction_10089011", "reaction_10090115", "reaction_10090369", "reaction_10090246", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10089985", "reaction_10092370", "reaction_10090098", "reaction_10090266", "reaction_10089149", "reaction_10091864", "reaction_10089952", "reaction_10092020" ] }, "R-BTA-69306": { "id": "pathway_10092402", "reactome": "R-BTA-69306", "name": "DNA Replication", "reactions": [ "reaction_10033379", "reaction_10033512", "reaction_10033504", "reaction_10040183", "reaction_10033466", "reaction_10033412", "reaction_10033473" ] }, "R-BTA-4086400": { "id": "pathway_10094382", "reactome": "R-BTA-4086400", "name": "PCP/CE pathway", "reactions": [ "reaction_10068923", "reaction_10069882", "reaction_10068933", "reaction_10069876", "reaction_10069896", "reaction_10068939", "reaction_10069593", "reaction_10069299", "reaction_10069872", "reaction_10069595" ] }, "R-BTA-9603381": { "id": "pathway_10094968", "reactome": "R-BTA-9603381", "name": "Activated NTRK3 signals through PI3K", "reactions": [ "reaction_10090727", "reaction_10090722" ] }, "R-BTA-196780": { "id": "pathway_10093320", "reactome": "R-BTA-196780", "name": "Biotin transport and metabolism", "reactions": [ "reaction_10066401", "reaction_10067733", "reaction_10042657" ] }, "R-BTA-500792": { "id": "pathway_10092986", "reactome": "R-BTA-500792", "name": "GPCR ligand binding", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048304", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10049643", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10086565", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10049681", "reaction_10067358", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-1296067": { "id": "pathway_10094034", "reactome": "R-BTA-1296067", "name": "Potassium transport channels", "reactions": [ "reaction_10057399" ] }, "R-BTA-1299287": { "id": "pathway_10094052", "reactome": "R-BTA-1299287", "name": "Tandem pore domain halothane-inhibited K+ channel (THIK)", "reactions": [ "reaction_10057616" ] }, "R-BTA-189445": { "id": "pathway_10092922", "reactome": "R-BTA-189445", "name": "Metabolism of porphyrins", "reactions": [ "reaction_10038338", "reaction_10040682", "reaction_10091613", "reaction_10040636", "reaction_10040688", "reaction_10038336", "reaction_10091598", "reaction_10091611", "reaction_10040672", "reaction_10040645", "reaction_10040663", "reaction_10040654", "reaction_10091605", "reaction_10066416" ] }, "R-BTA-6804114": { "id": "pathway_10094656", "reactome": "R-BTA-6804114", "name": "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest", "reactions": [ "reaction_10077955", "reaction_10078349", "reaction_10081499" ] }, "R-BTA-446205": { "id": "pathway_10093778", "reactome": "R-BTA-446205", "name": "Synthesis of GDP-mannose", "reactions": [ "reaction_10049831" ] }, "R-BTA-428890": { "id": "pathway_10093526", "reactome": "R-BTA-428890", "name": "Role of ABL in ROBO-SLIT signaling", "reactions": [ "reaction_10045517", "reaction_10049024" ] }, "R-BTA-379401": { "id": "pathway_10093540", "reactome": "R-BTA-379401", "name": "Dopamine clearance from the synaptic cleft", "reactions": [ "reaction_10046151", "reaction_10046153", "reaction_10088657" ] }, "R-BTA-9670095": { "id": "pathway_10095020", "reactome": "R-BTA-9670095", "name": "Inhibition of DNA recombination at telomere", "reactions": [ "reaction_10091685" ] }, "R-BTA-6783589": { "id": "pathway_10093962", "reactome": "R-BTA-6783589", "name": "Interleukin-6 family signaling", "reactions": [ "reaction_10056207", "reaction_10056201", "reaction_10056127", "reaction_10056130", "reaction_10056188", "reaction_10056123", "reaction_10077455", "reaction_10056178", "reaction_10056205", "reaction_10056199", "reaction_10077422", "reaction_10056170", "reaction_10056194", "reaction_10056110", "reaction_10056176", "reaction_10056172", "reaction_10056168", "reaction_10056132", "reaction_10056185", "reaction_10056102", "reaction_10091747", "reaction_10077424" ] }, "R-BTA-9020956": { "id": "pathway_10093786", "reactome": "R-BTA-9020956", "name": "Interleukin-27 signaling", "reactions": [ "reaction_10049970", "reaction_10087766", "reaction_10087783", "reaction_10087726", "reaction_10087787", "reaction_10087793", "reaction_10087671", "reaction_10087774", "reaction_10049946" ] }, "R-BTA-8939236": { "id": "pathway_10094858", "reactome": "R-BTA-8939236", "name": "RUNX1 regulates transcription of genes involved in differentiation of HSCs", "reactions": [ "reaction_10088872", "reaction_10088876", "reaction_10088887" ] }, "R-BTA-6803205": { "id": "pathway_10094674", "reactome": "R-BTA-6803205", "name": "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain", "reactions": [ "reaction_10080789", "reaction_10080738" ] }, "R-BTA-157858": { "id": "pathway_10093210", "reactome": "R-BTA-157858", "name": "Gap junction trafficking and regulation", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040967", "reaction_10040842", "reaction_10040961", "reaction_10040955", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-192105": { "id": "pathway_10093236", "reactome": "R-BTA-192105", "name": "Synthesis of bile acids and bile salts", "reactions": [ "reaction_10041337", "reaction_10041197", "reaction_10041377", "reaction_10041172", "reaction_10041308", "reaction_10041343", "reaction_10041363", "reaction_10041177", "reaction_10041208", "reaction_10085316", "reaction_10041104", "reaction_10041357", "reaction_10085291", "reaction_10041226", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041323", "reaction_10041349", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041351", "reaction_10041371", "reaction_10041375", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041335", "reaction_10041210", "reaction_10041327", "reaction_10041193", "reaction_10041353", "reaction_10041317", "reaction_10041361", "reaction_10041345", "reaction_10041204", "reaction_10041319", "reaction_10041367", "reaction_10041339", "reaction_10041097", "reaction_10041179", "reaction_10041217", "reaction_10041206", "reaction_10041301", "reaction_10041373", "reaction_10041195", "reaction_10041369" ] }, "R-BTA-190840": { "id": "pathway_10093202", "reactome": "R-BTA-190840", "name": "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane", "reactions": [ "reaction_10040842", "reaction_10040857" ] }, "R-BTA-72695": { "id": "pathway_10092580", "reactome": "R-BTA-72695", "name": "Formation of the ternary complex, and subsequently, the 43S complex", "reactions": [ "reaction_10034387", "reaction_10034383", "reaction_10034905" ] }, "R-BTA-427413": { "id": "pathway_10093712", "reactome": "R-BTA-427413", "name": "NoRC negatively regulates rRNA expression", "reactions": [ "reaction_10048682" ] }, "R-BTA-9674555": { "id": "pathway_10095034", "reactome": "R-BTA-9674555", "name": "Signaling by CSF3 (G-CSF)", "reactions": [ "reaction_10092257", "reaction_10092108" ] }, "R-BTA-5576891": { "id": "pathway_10093668", "reactome": "R-BTA-5576891", "name": "Cardiac conduction", "reactions": [ "reaction_10048504", "reaction_10057418", "reaction_10071819", "reaction_10071843", "reaction_10077468", "reaction_10047893", "reaction_10071824", "reaction_10053180", "reaction_10048787", "reaction_10071800", "reaction_10091759", "reaction_10071876" ] }, "R-BTA-166786": { "id": "pathway_10093112", "reactome": "R-BTA-166786", "name": "Creation of C4 and C2 activators", "reactions": [ "reaction_10039782", "reaction_10039778" ] }, "R-BTA-9696270": { "id": "pathway_10095026", "reactome": "R-BTA-9696270", "name": "RND2 GTPase cycle", "reactions": [ "reaction_10091994", "reaction_10092022" ] }, "R-BTA-189085": { "id": "pathway_10093160", "reactome": "R-BTA-189085", "name": "Digestion of dietary carbohydrate", "reactions": [ "reaction_10040866", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10073378", "reaction_10040608", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-6799990": { "id": "pathway_10093980", "reactome": "R-BTA-6799990", "name": "Metal sequestration by antimicrobial proteins", "reactions": [ "reaction_10078759", "reaction_10056416", "reaction_10070906" ] }, "R-BTA-1169408": { "id": "pathway_10093970", "reactome": "R-BTA-1169408", "name": "ISG15 antiviral mechanism", "reactions": [ "reaction_10060730", "reaction_10060732", "reaction_10056315", "reaction_10056289", "reaction_10056283", "reaction_10060694", "reaction_10056287", "reaction_10056297" ] }, "R-BTA-376172": { "id": "pathway_10093522", "reactome": "R-BTA-376172", "name": "DSCAM interactions", "reactions": [ "reaction_10045509" ] }, "R-BTA-5689880": { "id": "pathway_10094372", "reactome": "R-BTA-5689880", "name": "Ub-specific processing proteases", "reactions": [ "reaction_10077034", "reaction_10077070", "reaction_10077349", "reaction_10068095", "reaction_10075808", "reaction_10075550", "reaction_10077292", "reaction_10077363", "reaction_10077331", "reaction_10077371", "reaction_10075902", "reaction_10077317", "reaction_10077339", "reaction_10075561", "reaction_10077393", "reaction_10075891", "reaction_10077379" ] }, "R-BTA-430039": { "id": "pathway_10093744", "reactome": "R-BTA-430039", "name": "mRNA decay by 5' to 3' exoribonuclease", "reactions": [ "reaction_10049232" ] }, "R-BTA-216083": { "id": "pathway_10093316", "reactome": "R-BTA-216083", "name": "Integrin cell surface interactions", "reactions": [ "reaction_10042253", "reaction_10069412" ] }, "R-BTA-5693567": { "id": "pathway_10092678", "reactome": "R-BTA-5693567", "name": "HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)", "reactions": [ "reaction_10075165", "reaction_10074877", "reaction_10075151", "reaction_10076339", "reaction_10075037", "reaction_10035846", "reaction_10075181", "reaction_10074798" ] }, "R-BTA-110373": { "id": "pathway_10094850", "reactome": "R-BTA-110373", "name": "Resolution of AP sites via the multiple-nucleotide patch replacement pathway", "reactions": [ "reaction_10088526" ] }, "R-BTA-69656": { "id": "pathway_10093152", "reactome": "R-BTA-69656", "name": "Cyclin A:Cdk2-associated events at S phase entry", "reactions": [ "reaction_10040521", "reaction_10083565", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-975138": { "id": "pathway_10093024", "reactome": "R-BTA-975138", "name": "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-391906": { "id": "pathway_10093630", "reactome": "R-BTA-391906", "name": "Leukotriene receptors", "reactions": [ "reaction_10047396", "reaction_10047378", "reaction_10047398", "reaction_10091763", "reaction_10091812" ] }, "R-BTA-2046105": { "id": "pathway_10094216", "reactome": "R-BTA-2046105", "name": "Linoleic acid (LA) metabolism", "reactions": [ "reaction_10063450", "reaction_10063454", "reaction_10063413", "reaction_10063442", "reaction_10063446", "reaction_10063448", "reaction_10063444", "reaction_10063452" ] }, "R-BTA-194138": { "id": "pathway_10093158", "reactome": "R-BTA-194138", "name": "Signaling by VEGF", "reactions": [ "reaction_10070624", "reaction_10041649", "reaction_10071504", "reaction_10041463", "reaction_10070589", "reaction_10070628", "reaction_10071506", "reaction_10040570", "reaction_10069535", "reaction_10071508", "reaction_10070651", "reaction_10070645", "reaction_10041657", "reaction_10070594", "reaction_10070615", "reaction_10070676", "reaction_10070596", "reaction_10065227", "reaction_10070657", "reaction_10041453" ] }, "R-BTA-176408": { "id": "pathway_10092894", "reactome": "R-BTA-176408", "name": "Regulation of APC/C activators between G1/S and early anaphase", "reactions": [ "reaction_10039801", "reaction_10038033", "reaction_10039852", "reaction_10038035" ] }, "R-BTA-9619229": { "id": "pathway_10094990", "reactome": "R-BTA-9619229", "name": "Activation of RAC1 downstream of NMDARs", "reactions": [ "reaction_10091067", "reaction_10091075" ] }, "R-BTA-8963898": { "id": "pathway_10094580", "reactome": "R-BTA-8963898", "name": "Plasma lipoprotein assembly", "reactions": [ "reaction_10074486", "reaction_10074474" ] }, "R-BTA-68886": { "id": "pathway_10094260", "reactome": "R-BTA-68886", "name": "M Phase", "reactions": [ "reaction_10065708", "reaction_10066345", "reaction_10091132", "reaction_10065572", "reaction_10091656", "reaction_10065095", "reaction_10065563", "reaction_10091141", "reaction_10065794", "reaction_10070705", "reaction_10091661", "reaction_10064733", "reaction_10065177", "reaction_10064904", "reaction_10065201", "reaction_10069491", "reaction_10065726", "reaction_10091634", "reaction_10091145", "reaction_10091658", "reaction_10066324" ] }, "R-BTA-8854691": { "id": "pathway_10093792", "reactome": "R-BTA-8854691", "name": "Interleukin-20 family signaling", "reactions": [ "reaction_10089538", "reaction_10089542", "reaction_10089466", "reaction_10089506", "reaction_10089455", "reaction_10089442", "reaction_10089516", "reaction_10089446", "reaction_10089444", "reaction_10089453", "reaction_10089431", "reaction_10089540", "reaction_10089427", "reaction_10089536", "reaction_10089511", "reaction_10050054", "reaction_10089480", "reaction_10089523", "reaction_10089530" ] }, "R-BTA-2022090": { "id": "pathway_10094086", "reactome": "R-BTA-2022090", "name": "Assembly of collagen fibrils and other multimeric structures", "reactions": [ "reaction_10065929", "reaction_10058705", "reaction_10064953", "reaction_10064959" ] }, "R-BTA-74160": { "id": "pathway_10092440", "reactome": "R-BTA-74160", "name": "Gene expression (Transcription)", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10048682", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10071065", "reaction_10037185", "reaction_10048720", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10044390", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10081561", "reaction_10080457", "reaction_10035301", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10035854", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10044381", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10038904", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10035254", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10070702", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10070700", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10044333", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10044361", "reaction_10086502", "reaction_10091096", "reaction_10087862", "reaction_10046681", "reaction_10081499", "reaction_10048717", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10037201" ] }, "R-BTA-399954": { "id": "pathway_10093646", "reactome": "R-BTA-399954", "name": "Sema3A PAK dependent Axon repulsion", "reactions": [ "reaction_10047618", "reaction_10047763", "reaction_10047659" ] }, "R-BTA-5696395": { "id": "pathway_10092742", "reactome": "R-BTA-5696395", "name": "Formation of Incision Complex in GG-NER", "reactions": [ "reaction_10036661", "reaction_10077016" ] }, "R-BTA-1483148": { "id": "pathway_10094116", "reactome": "R-BTA-1483148", "name": "Synthesis of PG", "reactions": [ "reaction_10059101" ] }, "R-BTA-2142691": { "id": "pathway_10093434", "reactome": "R-BTA-2142691", "name": "Synthesis of Leukotrienes (LT) and Eoxins (EX)", "reactions": [ "reaction_10064482", "reaction_10064581", "reaction_10044657", "reaction_10064503", "reaction_10044151" ] }, "R-BTA-3858494": { "id": "pathway_10094384", "reactome": "R-BTA-3858494", "name": "Beta-catenin independent WNT signaling", "reactions": [ "reaction_10069456", "reaction_10069459", "reaction_10068923", "reaction_10069882", "reaction_10069448", "reaction_10068933", "reaction_10069876", "reaction_10069896", "reaction_10068939", "reaction_10069593", "reaction_10069299", "reaction_10069872", "reaction_10069595" ] }, "R-BTA-382551": { "id": "pathway_10092732", "reactome": "R-BTA-382551", "name": "Transport of small molecules", "reactions": [ "reaction_10052907", "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10066227", "reaction_10049371", "reaction_10086004", "reaction_10047893", "reaction_10053143", "reaction_10085994", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10052916", "reaction_10049319", "reaction_10066034", "reaction_10045494", "reaction_10081968", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10057062", "reaction_10066289", "reaction_10049080", "reaction_10049241", "reaction_10065991", "reaction_10091759", "reaction_10086343", "reaction_10044978", "reaction_10051892", "reaction_10076099", "reaction_10074474", "reaction_10087646", "reaction_10085907", "reaction_10052888", "reaction_10076179", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10074493", "reaction_10071462", "reaction_10045501", "reaction_10049464", "reaction_10057070", "reaction_10052923", "reaction_10045473", "reaction_10051136", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10066270", "reaction_10048795", "reaction_10086002", "reaction_10086026", "reaction_10066199", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10070728", "reaction_10059181", "reaction_10058792", "reaction_10051145", "reaction_10083113", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10067332", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10066277", "reaction_10052909", "reaction_10070906", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10049262", "reaction_10051547", "reaction_10074360", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10091542", "reaction_10071254", "reaction_10087365", "reaction_10070743", "reaction_10092050", "reaction_10044962", "reaction_10072522", "reaction_10051141", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10070735", "reaction_10048504", "reaction_10066004", "reaction_10057007", "reaction_10049440", "reaction_10044547", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10053258", "reaction_10051143", "reaction_10071490", "reaction_10049083", "reaction_10058790", "reaction_10048768", "reaction_10058216", "reaction_10058469", "reaction_10049378", "reaction_10040636", "reaction_10049869", "reaction_10044941", "reaction_10086557", "reaction_10053180", "reaction_10048491", "reaction_10084767", "reaction_10088982", "reaction_10051276", "reaction_10047900", "reaction_10074686", "reaction_10071469", "reaction_10044934", "reaction_10089029", "reaction_10051148", "reaction_10076091", "reaction_10065965", "reaction_10089048", "reaction_10049385", "reaction_10051545", "reaction_10066206", "reaction_10044955", "reaction_10091583", "reaction_10049243", "reaction_10074486", "reaction_10066232", "reaction_10085384", "reaction_10052925", "reaction_10067346", "reaction_10051587", "reaction_10048754", "reaction_10052866", "reaction_10066282", "reaction_10057832", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10052914", "reaction_10036297", "reaction_10071001", "reaction_10052901", "reaction_10051879", "reaction_10076083", "reaction_10046707", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10076172", "reaction_10048787", "reaction_10046698", "reaction_10051150", "reaction_10077487", "reaction_10049053", "reaction_10071280", "reaction_10048821", "reaction_10089060", "reaction_10049628", "reaction_10049447", "reaction_10044666", "reaction_10089058", "reaction_10071003", "reaction_10047483", "reaction_10049271", "reaction_10049253", "reaction_10066021", "reaction_10052911", "reaction_10071476", "reaction_10089062", "reaction_10051866", "reaction_10053210", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10084509", "reaction_10084300", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10077489", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-9033658": { "id": "pathway_10094960", "reactome": "R-BTA-9033658", "name": "Blood group systems biosynthesis", "reactions": [ "reaction_10090620", "reaction_10090631", "reaction_10090799", "reaction_10090774", "reaction_10090611", "reaction_10090645", "reaction_10090703", "reaction_10090867", "reaction_10090638", "reaction_10090797", "reaction_10090822", "reaction_10090854", "reaction_10090772", "reaction_10090856", "reaction_10090851", "reaction_10090819", "reaction_10090802" ] }, "R-BTA-597592": { "id": "pathway_10092946", "reactome": "R-BTA-597592", "name": "Post-translational protein modification", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10081490", "reaction_10049811", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10043698", "reaction_10088807", "reaction_10069329", "reaction_10069498", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10082038", "reaction_10083380", "reaction_10087883", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10077363", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10077034", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10076119", "reaction_10056074", "reaction_10076773", "reaction_10077331", "reaction_10082045", "reaction_10049831", "reaction_10038408", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10076610", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10049789", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10076586", "reaction_10040933", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10088734", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10048958", "reaction_10087848" ] }, "R-BTA-5663220": { "id": "pathway_10093364", "reactome": "R-BTA-5663220", "name": "RHO GTPases Activate Formins", "reactions": [ "reaction_10073549", "reaction_10073569", "reaction_10073561", "reaction_10073525", "reaction_10073547", "reaction_10068933", "reaction_10068939", "reaction_10043461", "reaction_10073493", "reaction_10073503", "reaction_10073507", "reaction_10073559", "reaction_10073557" ] }, "R-BTA-450302": { "id": "pathway_10093798", "reactome": "R-BTA-450302", "name": "activated TAK1 mediates p38 MAPK activation", "reactions": [ "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10050231" ] }, "R-BTA-73762": { "id": "pathway_10092604", "reactome": "R-BTA-73762", "name": "RNA Polymerase I Transcription Initiation", "reactions": [ "reaction_10035301" ] }, "R-BTA-156587": { "id": "pathway_10092936", "reactome": "R-BTA-156587", "name": "Amino Acid conjugation", "reactions": [ "reaction_10038382", "reaction_10038380", "reaction_10038371", "reaction_10038354", "reaction_10040185" ] }, "R-BTA-69895": { "id": "pathway_10094682", "reactome": "R-BTA-69895", "name": "Transcriptional activation of cell cycle inhibitor p21 ", "reactions": [ "reaction_10081470" ] }, "R-BTA-140875": { "id": "pathway_10092872", "reactome": "R-BTA-140875", "name": "Common Pathway of Fibrin Clot Formation", "reactions": [ "reaction_10090181", "reaction_10037845", "reaction_10037923", "reaction_10037800", "reaction_10090183", "reaction_10037950", "reaction_10037815", "reaction_10037927", "reaction_10037948", "reaction_10071906", "reaction_10037852" ] }, "R-BTA-71336": { "id": "pathway_10092466", "reactome": "R-BTA-71336", "name": "Pentose phosphate pathway", "reactions": [ "reaction_10088898", "reaction_10034043", "reaction_10034041", "reaction_10034013", "reaction_10088744", "reaction_10089230", "reaction_10077793", "reaction_10034944", "reaction_10033592", "reaction_10034032", "reaction_10042801", "reaction_10036903" ] }, "R-BTA-5652084": { "id": "pathway_10092462", "reactome": "R-BTA-5652084", "name": "Fructose metabolism", "reactions": [ "reaction_10072825", "reaction_10083115", "reaction_10033570", "reaction_10033561" ] }, "R-BTA-5358351": { "id": "pathway_10094476", "reactome": "R-BTA-5358351", "name": "Signaling by Hedgehog", "reactions": [ "reaction_10072138", "reaction_10072220", "reaction_10072123", "reaction_10072199", "reaction_10072606", "reaction_10072720", "reaction_10072677", "reaction_10072715", "reaction_10072685", "reaction_10072154", "reaction_10072081", "reaction_10072713" ] }, "R-BTA-9034793": { "id": "pathway_10094966", "reactome": "R-BTA-9034793", "name": "Activated NTRK3 signals through PLCG1", "reactions": [ "reaction_10090675" ] }, "R-BTA-1483249": { "id": "pathway_10094168", "reactome": "R-BTA-1483249", "name": "Inositol phosphate metabolism", "reactions": [ "reaction_10061067", "reaction_10061128", "reaction_10061137", "reaction_10063020", "reaction_10060917", "reaction_10063018", "reaction_10061034", "reaction_10061017", "reaction_10061134", "reaction_10061031", "reaction_10060938", "reaction_10060986", "reaction_10061011", "reaction_10061043", "reaction_10061079", "reaction_10061076", "reaction_10061040", "reaction_10061131", "reaction_10061046", "reaction_10060963", "reaction_10061061", "reaction_10060980", "reaction_10061014", "reaction_10061122", "reaction_10061113", "reaction_10061024", "reaction_10060983", "reaction_10061052", "reaction_10061119", "reaction_10061006", "reaction_10061116", "reaction_10060956", "reaction_10061084", "reaction_10061049", "reaction_10061064", "reaction_10061125", "reaction_10060951", "reaction_10060993", "reaction_10061037" ] }, "R-BTA-9007892": { "id": "pathway_10094878", "reactome": "R-BTA-9007892", "name": "Interleukin-38 signaling", "reactions": [ "reaction_10089595", "reaction_10089597", "reaction_10089591" ] }, "R-BTA-983231": { "id": "pathway_10093948", "reactome": "R-BTA-983231", "name": "Factors involved in megakaryocyte development and platelet production", "reactions": [ "reaction_10055515", "reaction_10055920", "reaction_10055829", "reaction_10055870", "reaction_10055649", "reaction_10055647", "reaction_10055645", "reaction_10055995", "reaction_10055831", "reaction_10055827", "reaction_10055933", "reaction_10055847", "reaction_10056002", "reaction_10055823", "reaction_10055529", "reaction_10055833" ] }, "R-BTA-5689896": { "id": "pathway_10094620", "reactome": "R-BTA-5689896", "name": "Ovarian tumor domain proteases", "reactions": [ "reaction_10077406", "reaction_10075984", "reaction_10075989", "reaction_10075970", "reaction_10085345", "reaction_10084931", "reaction_10076001", "reaction_10075952" ] }, "R-BTA-72086": { "id": "pathway_10092700", "reactome": "R-BTA-72086", "name": "mRNA Capping", "reactions": [ "reaction_10036003" ] }, "R-BTA-983169": { "id": "pathway_10093380", "reactome": "R-BTA-983169", "name": "Class I MHC mediated antigen processing & presentation", "reactions": [ "reaction_10055783", "reaction_10055491", "reaction_10056835", "reaction_10084867", "reaction_10055821", "reaction_10087823", "reaction_10087807", "reaction_10057004", "reaction_10054866", "reaction_10056912", "reaction_10055448", "reaction_10055451", "reaction_10056910", "reaction_10056982", "reaction_10056914", "reaction_10056903", "reaction_10055431", "reaction_10055453", "reaction_10055817", "reaction_10056805", "reaction_10055444", "reaction_10084865", "reaction_10055819", "reaction_10055460", "reaction_10043659" ] }, "R-BTA-4641258": { "id": "pathway_10094404", "reactome": "R-BTA-4641258", "name": "Degradation of DVL", "reactions": [ "reaction_10069607" ] }, "R-BTA-69620": { "id": "pathway_10092450", "reactome": "R-BTA-69620", "name": "Cell Cycle Checkpoints", "reactions": [ "reaction_10081470", "reaction_10084051", "reaction_10033535", "reaction_10076341", "reaction_10084047", "reaction_10038033", "reaction_10038035", "reaction_10074692", "reaction_10078408", "reaction_10074695", "reaction_10040059" ] }, "R-BTA-8848584": { "id": "pathway_10093600", "reactome": "R-BTA-8848584", "name": "Wax and plasmalogen biosynthesis", "reactions": [ "reaction_10047065", "reaction_10077001", "reaction_10083575", "reaction_10083577" ] }, "R-BTA-111367": { "id": "pathway_10092768", "reactome": "R-BTA-111367", "name": "SLBP independent Processing of Histone Pre-mRNAs", "reactions": [ "reaction_10036915", "reaction_10036917" ] }, "R-BTA-74751": { "id": "pathway_10092642", "reactome": "R-BTA-74751", "name": "Insulin receptor signalling cascade", "reactions": [ "reaction_10036590", "reaction_10038450", "reaction_10036598", "reaction_10035527", "reaction_10035536", "reaction_10036570", "reaction_10075097", "reaction_10035507", "reaction_10036607", "reaction_10036616", "reaction_10075065" ] }, "R-BTA-1638074": { "id": "pathway_10093852", "reactome": "R-BTA-1638074", "name": "Keratan sulfate/keratin metabolism", "reactions": [ "reaction_10063530", "reaction_10063485", "reaction_10063520", "reaction_10063232", "reaction_10063249", "reaction_10063510", "reaction_10063508", "reaction_10091293", "reaction_10060293", "reaction_10060285", "reaction_10063532", "reaction_10063477", "reaction_10051589", "reaction_10060295" ] }, "R-BTA-881907": { "id": "pathway_10093308", "reactome": "R-BTA-881907", "name": "Gastrin-CREB signalling pathway via PKC and MAPK", "reactions": [ "reaction_10064919", "reaction_10064915", "reaction_10064910", "reaction_10041950" ] }, "R-BTA-2871809": { "id": "pathway_10094316", "reactome": "R-BTA-2871809", "name": "FCERI mediated Ca+2 mobilization", "reactions": [ "reaction_10066052", "reaction_10066102", "reaction_10066094" ] }, "R-BTA-198725": { "id": "pathway_10093306", "reactome": "R-BTA-198725", "name": "Nuclear Events (kinase and transcription factor activation)", "reactions": [ "reaction_10042826", "reaction_10090994", "reaction_10043488", "reaction_10041950" ] }, "R-BTA-6804759": { "id": "pathway_10094340", "reactome": "R-BTA-6804759", "name": "Regulation of TP53 Activity through Association with Co-factors", "reactions": [ "reaction_10081470", "reaction_10081522", "reaction_10081530", "reaction_10080797", "reaction_10081889", "reaction_10080811", "reaction_10066764" ] }, "R-BTA-5693565": { "id": "pathway_10094582", "reactome": "R-BTA-5693565", "name": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks", "reactions": [ "reaction_10074695", "reaction_10076329", "reaction_10076334", "reaction_10075173", "reaction_10074550", "reaction_10076341", "reaction_10074670", "reaction_10074739", "reaction_10074747", "reaction_10074677", "reaction_10074558", "reaction_10076293", "reaction_10074679", "reaction_10074692", "reaction_10076303", "reaction_10074736", "reaction_10074720", "reaction_10076332" ] }, "R-BTA-109606": { "id": "pathway_10092818", "reactome": "R-BTA-109606", "name": "Intrinsic Pathway for Apoptosis", "reactions": [ "reaction_10037731", "reaction_10051175", "reaction_10037678", "reaction_10037706", "reaction_10037618", "reaction_10037253", "reaction_10091191", "reaction_10037723", "reaction_10037702", "reaction_10037277", "reaction_10091197", "reaction_10037293", "reaction_10081897", "reaction_10038007", "reaction_10037630", "reaction_10091186", "reaction_10091188", "reaction_10051181", "reaction_10037739", "reaction_10037237", "reaction_10037674", "reaction_10039520", "reaction_10037289", "reaction_10037264", "reaction_10037727", "reaction_10037622", "reaction_10037641" ] }, "R-BTA-9614399": { "id": "pathway_10094982", "reactome": "R-BTA-9614399", "name": "Regulation of localization of FOXO transcription factors", "reactions": [ "reaction_10091033", "reaction_10091023", "reaction_10091029", "reaction_10091017" ] }, "R-BTA-425381": { "id": "pathway_10093700", "reactome": "R-BTA-425381", "name": "Bicarbonate transporters", "reactions": [ "reaction_10048478", "reaction_10048491" ] }, "R-BTA-1257604": { "id": "pathway_10094150", "reactome": "R-BTA-1257604", "name": "PIP3 activates AKT signaling", "reactions": [ "reaction_10060556", "reaction_10065227", "reaction_10060448", "reaction_10065099", "reaction_10087531" ] }, "R-BTA-5658623": { "id": "pathway_10094534", "reactome": "R-BTA-5658623", "name": "FGFRL1 modulation of FGFR1 signaling", "reactions": [ "reaction_10073071", "reaction_10073077" ] }, "R-BTA-211981": { "id": "pathway_10092690", "reactome": "R-BTA-211981", "name": "Xenobiotics", "reactions": [ "reaction_10044477", "reaction_10044265", "reaction_10044182", "reaction_10035911", "reaction_10044167", "reaction_10035878", "reaction_10044223", "reaction_10044280", "reaction_10044250", "reaction_10044275", "reaction_10044204", "reaction_10035861", "reaction_10035977", "reaction_10035865", "reaction_10044218", "reaction_10044270" ] }, "R-BTA-193993": { "id": "pathway_10093246", "reactome": "R-BTA-193993", "name": "Mineralocorticoid biosynthesis", "reactions": [ "reaction_10041386", "reaction_10041397", "reaction_10041719", "reaction_10041269", "reaction_10041415", "reaction_10041393" ] }, "R-BTA-2151201": { "id": "pathway_10094608", "reactome": "R-BTA-2151201", "name": "Transcriptional activation of mitochondrial biogenesis", "reactions": [ "reaction_10075362", "reaction_10075350" ] }, "R-BTA-9031628": { "id": "pathway_10094978", "reactome": "R-BTA-9031628", "name": "NGF-stimulated transcription", "reactions": [ "reaction_10090994" ] }, "R-BTA-210990": { "id": "pathway_10093420", "reactome": "R-BTA-210990", "name": "PECAM1 interactions", "reactions": [ "reaction_10044024", "reaction_10044018", "reaction_10044034", "reaction_10044030", "reaction_10044039", "reaction_10044043" ] }, "R-BTA-77288": { "id": "pathway_10092724", "reactome": "R-BTA-77288", "name": "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids", "reactions": [ "reaction_10036220", "reaction_10036664", "reaction_10036218" ] }, "R-BTA-2024101": { "id": "pathway_10094122", "reactome": "R-BTA-2024101", "name": "CS/DS degradation", "reactions": [ "reaction_10060842", "reaction_10060031", "reaction_10091289", "reaction_10060829", "reaction_10062655", "reaction_10060825", "reaction_10063807", "reaction_10060827" ] }, "R-BTA-1614635": { "id": "pathway_10094008", "reactome": "R-BTA-1614635", "name": "Sulfur amino acid metabolism", "reactions": [ "reaction_10060361", "reaction_10060216", "reaction_10060275", "reaction_10057023", "reaction_10060255", "reaction_10060228", "reaction_10089959", "reaction_10060250", "reaction_10060264", "reaction_10089850", "reaction_10060218", "reaction_10060234", "reaction_10057032", "reaction_10077124", "reaction_10060207", "reaction_10057684", "reaction_10060252", "reaction_10090013", "reaction_10090015", "reaction_10090671", "reaction_10060231", "reaction_10083204", "reaction_10090679", "reaction_10090681" ] }, "R-BTA-380615": { "id": "pathway_10092884", "reactome": "R-BTA-380615", "name": "Serotonin clearance from the synaptic cleft", "reactions": [ "reaction_10046552", "reaction_10038000" ] }, "R-BTA-156580": { "id": "pathway_10092696", "reactome": "R-BTA-156580", "name": "Phase II - Conjugation of compounds", "reactions": [ "reaction_10040147", "reaction_10039887", "reaction_10038371", "reaction_10038318", "reaction_10077658", "reaction_10039874", "reaction_10038338", "reaction_10035863", "reaction_10038231", "reaction_10040136", "reaction_10040129", "reaction_10039749", "reaction_10039890", "reaction_10076900", "reaction_10048727", "reaction_10040131", "reaction_10040030", "reaction_10076898", "reaction_10040122", "reaction_10057079", "reaction_10040157", "reaction_10039865", "reaction_10040112", "reaction_10071924", "reaction_10038382", "reaction_10076799", "reaction_10038380", "reaction_10040115", "reaction_10039918", "reaction_10038238", "reaction_10087515", "reaction_10040120", "reaction_10038320", "reaction_10038340", "reaction_10039921", "reaction_10038354", "reaction_10040152", "reaction_10040107", "reaction_10039930", "reaction_10040098", "reaction_10051570", "reaction_10088617", "reaction_10038336", "reaction_10040021", "reaction_10040117", "reaction_10067425", "reaction_10039916", "reaction_10076785", "reaction_10039923", "reaction_10076133", "reaction_10088580", "reaction_10076903", "reaction_10038316", "reaction_10040185" ] }, "R-BTA-425366": { "id": "pathway_10093480", "reactome": "R-BTA-425366", "name": "Transport of bile salts and organic acids, metal ions and amine compounds", "reactions": [ "reaction_10049402", "reaction_10049333", "reaction_10051314", "reaction_10051307", "reaction_10049090", "reaction_10049464", "reaction_10049583", "reaction_10049635", "reaction_10049371", "reaction_10049440", "reaction_10051325", "reaction_10049358", "reaction_10049326", "reaction_10045487", "reaction_10051269", "reaction_10049871", "reaction_10049628", "reaction_10049447", "reaction_10049433", "reaction_10049319", "reaction_10049378", "reaction_10049869", "reaction_10045419", "reaction_10044941", "reaction_10049060", "reaction_10049613", "reaction_10051276", "reaction_10049592", "reaction_10045480", "reaction_10049606", "reaction_10051305", "reaction_10049599", "reaction_10049392", "reaction_10044934", "reaction_10049078", "reaction_10051283", "reaction_10049385", "reaction_10088912", "reaction_10051286", "reaction_10044948" ] }, "R-BTA-450321": { "id": "pathway_10093800", "reactome": "R-BTA-450321", "name": "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1", "reactions": [ "reaction_10050256" ] }, "R-BTA-426048": { "id": "pathway_10093708", "reactome": "R-BTA-426048", "name": "Arachidonate production from DAG", "reactions": [ "reaction_10048587", "reaction_10076743", "reaction_10048580" ] }, "R-BTA-429958": { "id": "pathway_10093740", "reactome": "R-BTA-429958", "name": "mRNA decay by 3' to 5' exoribonuclease", "reactions": [ "reaction_10049230" ] }, "R-BTA-446353": { "id": "pathway_10093752", "reactome": "R-BTA-446353", "name": "Cell-extracellular matrix interactions", "reactions": [ "reaction_10049891", "reaction_10049312", "reaction_10049883" ] }, "R-BTA-8941858": { "id": "pathway_10094788", "reactome": "R-BTA-8941858", "name": "Regulation of RUNX3 expression and activity", "reactions": [ "reaction_10086587", "reaction_10086581", "reaction_10088490", "reaction_10088482", "reaction_10084947", "reaction_10086589" ] }, "R-BTA-1059683": { "id": "pathway_10093960", "reactome": "R-BTA-1059683", "name": "Interleukin-6 signaling", "reactions": [ "reaction_10056207", "reaction_10056201", "reaction_10056127", "reaction_10056130", "reaction_10056188", "reaction_10056123", "reaction_10056178", "reaction_10056205", "reaction_10056199", "reaction_10056170", "reaction_10056194", "reaction_10056110", "reaction_10056176", "reaction_10056172", "reaction_10056168", "reaction_10056132", "reaction_10056185", "reaction_10056102", "reaction_10091747" ] }, "R-BTA-193807": { "id": "pathway_10093234", "reactome": "R-BTA-193807", "name": "Synthesis of bile acids and bile salts via 27-hydroxycholesterol", "reactions": [ "reaction_10041377", "reaction_10041097", "reaction_10041371", "reaction_10041375", "reaction_10041206", "reaction_10041373", "reaction_10041369" ] }, "R-BTA-556833": { "id": "pathway_10092528", "reactome": "R-BTA-556833", "name": "Metabolism of lipids", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10082880", "reaction_10041363", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10041359", "reaction_10071388", "reaction_10083575", "reaction_10060569", "reaction_10082934", "reaction_10058998", "reaction_10059977", "reaction_10036029", "reaction_10063444", "reaction_10060302", "reaction_10044657", "reaction_10063560", "reaction_10071344", "reaction_10041477", "reaction_10060448", "reaction_10064442", "reaction_10041500", "reaction_10047807", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10082152", "reaction_10085784", "reaction_10047001", "reaction_10076792", "reaction_10041357", "reaction_10047058", "reaction_10036021", "reaction_10064465", "reaction_10041415", "reaction_10033896", "reaction_10041310", "reaction_10059006", "reaction_10041290", "reaction_10064452", "reaction_10040895", "reaction_10041327", "reaction_10086403", "reaction_10085843", "reaction_10084480", "reaction_10041664", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10064546", "reaction_10082058", "reaction_10088928", "reaction_10085316", "reaction_10035417", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10041349", "reaction_10064474", "reaction_10060553", "reaction_10037748", "reaction_10090390", "reaction_10036042", "reaction_10041493", "reaction_10046989", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10041204", "reaction_10085775", "reaction_10047056", "reaction_10041301", "reaction_10041299", "reaction_10048882", "reaction_10041195", "reaction_10090468", "reaction_10076806", "reaction_10090394", "reaction_10041208", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10085291", "reaction_10058812", "reaction_10084424", "reaction_10040933", "reaction_10041424", "reaction_10064503", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10047065", "reaction_10059016", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10075631", "reaction_10041317", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10040922", "reaction_10060461", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10064516", "reaction_10058894", "reaction_10036220", "reaction_10060041", "reaction_10060614", "reaction_10084694", "reaction_10046992", "reaction_10041323", "reaction_10035786", "reaction_10086336", "reaction_10060600", "reaction_10049004", "reaction_10085798", "reaction_10060590", "reaction_10041437", "reaction_10041671", "reaction_10058916", "reaction_10041277", "reaction_10076281", "reaction_10060429", "reaction_10083369", "reaction_10059035", "reaction_10090379", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10049182", "reaction_10046984", "reaction_10090440", "reaction_10060572", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10040913", "reaction_10049163", "reaction_10048986", "reaction_10058908", "reaction_10041226", "reaction_10041341", "reaction_10035372", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10090460", "reaction_10041111", "reaction_10041170", "reaction_10063420", "reaction_10060476", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10047042", "reaction_10064479", "reaction_10059114", "reaction_10058892", "reaction_10049154", "reaction_10058945", "reaction_10041716", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10059141", "reaction_10060468", "reaction_10044599", "reaction_10041484", "reaction_10059991", "reaction_10054592", "reaction_10092062", "reaction_10035795", "reaction_10041397", "reaction_10088026", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10036664", "reaction_10083800", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10041367", "reaction_10059094", "reaction_10064445", "reaction_10041369", "reaction_10058943", "reaction_10033889", "reaction_10080887", "reaction_10059026", "reaction_10041365", "reaction_10059853", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10064534", "reaction_10040892", "reaction_10092065", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10090382", "reaction_10051261", "reaction_10041353", "reaction_10063456", "reaction_10059851", "reaction_10077004", "reaction_10051676", "reaction_10035812", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10058993", "reaction_10083577", "reaction_10036038", "reaction_10058913", "reaction_10085808", "reaction_10063430", "reaction_10063442", "reaction_10059984", "reaction_10059856", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10041319", "reaction_10041179", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10083211", "reaction_10064491", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10041377", "reaction_10065225", "reaction_10042961", "reaction_10041172", "reaction_10041486", "reaction_10058834", "reaction_10043885", "reaction_10058874", "reaction_10041386", "reaction_10059858", "reaction_10040881", "reaction_10060109", "reaction_10033912", "reaction_10058896", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10041193", "reaction_10090498", "reaction_10090510", "reaction_10048978", "reaction_10060498", "reaction_10041293", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10074353", "reaction_10090384", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10041412", "reaction_10083389", "reaction_10063564", "reaction_10085780", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10090489", "reaction_10059000", "reaction_10064578", "reaction_10059951", "reaction_10058910", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10060556", "reaction_10063413", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10086064", "reaction_10063437", "reaction_10036012", "reaction_10090464", "reaction_10088926", "reaction_10060550", "reaction_10041197", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10064581", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10090474", "reaction_10043984", "reaction_10063448", "reaction_10060021", "reaction_10077777", "reaction_10041297", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10058880", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10083547", "reaction_10041284", "reaction_10060597", "reaction_10090508", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10041321", "reaction_10090504", "reaction_10090392", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10084526", "reaction_10063428", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10044739", "reaction_10041721", "reaction_10060518", "reaction_10085340", "reaction_10043971", "reaction_10058809", "reaction_10085185", "reaction_10041347", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10041373", "reaction_10060535", "reaction_10063440", "reaction_10035838", "reaction_10059014", "reaction_10082136", "reaction_10043910", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10077835", "reaction_10047044", "reaction_10065223", "reaction_10058923", "reaction_10049161", "reaction_10085024", "reaction_10041379", "reaction_10060012", "reaction_10090386", "reaction_10058877", "reaction_10083092", "reaction_10086248", "reaction_10059121", "reaction_10040924", "reaction_10041502", "reaction_10058980", "reaction_10047033", "reaction_10058990", "reaction_10085806", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10048995", "reaction_10059860", "reaction_10059961", "reaction_10049116", "reaction_10060316", "reaction_10077001", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10088019", "reaction_10041335", "reaction_10064511", "reaction_10043964", "reaction_10082889", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10041217", "reaction_10059150", "reaction_10091936" ] }, "R-BTA-948021": { "id": "pathway_10093376", "reactome": "R-BTA-948021", "name": "Transport to the Golgi and subsequent modification", "reactions": [ "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10077710", "reaction_10053317", "reaction_10076708", "reaction_10076610", "reaction_10054467", "reaction_10054474", "reaction_10076584", "reaction_10053324", "reaction_10054418", "reaction_10076696", "reaction_10076635", "reaction_10076736", "reaction_10054438", "reaction_10076586", "reaction_10076706", "reaction_10053337", "reaction_10056061", "reaction_10056074", "reaction_10077717", "reaction_10082026", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10053339", "reaction_10076422", "reaction_10054411", "reaction_10076415", "reaction_10083380", "reaction_10054431", "reaction_10076778", "reaction_10053331", "reaction_10076698" ] }, "R-BTA-6794362": { "id": "pathway_10093578", "reactome": "R-BTA-6794362", "name": "Protein-protein interactions at synapses", "reactions": [ "reaction_10078674", "reaction_10078488", "reaction_10078566", "reaction_10084356", "reaction_10083793", "reaction_10046868", "reaction_10078522", "reaction_10078446", "reaction_10078682", "reaction_10078518", "reaction_10083789", "reaction_10078600", "reaction_10078464", "reaction_10078466" ] }, "R-BTA-4641265": { "id": "pathway_10094408", "reactome": "R-BTA-4641265", "name": "Repression of WNT target genes", "reactions": [ "reaction_10071356", "reaction_10087597", "reaction_10069651" ] }, "R-BTA-917937": { "id": "pathway_10093166", "reactome": "R-BTA-917937", "name": "Iron uptake and transport", "reactions": [ "reaction_10052907", "reaction_10052914", "reaction_10076099", "reaction_10049371", "reaction_10052916", "reaction_10052901", "reaction_10076083", "reaction_10052888", "reaction_10059181", "reaction_10040636", "reaction_10076091", "reaction_10052925", "reaction_10052909", "reaction_10070906", "reaction_10052911", "reaction_10052866", "reaction_10052923" ] }, "R-BTA-5358493": { "id": "pathway_10094448", "reactome": "R-BTA-5358493", "name": "Synthesis of diphthamide-EEF2", "reactions": [ "reaction_10071566", "reaction_10071579" ] }, "R-BTA-446199": { "id": "pathway_10093220", "reactome": "R-BTA-446199", "name": "Synthesis of Dolichyl-phosphate", "reactions": [ "reaction_10049804", "reaction_10069498", "reaction_10049818", "reaction_10040933" ] }, "R-BTA-140877": { "id": "pathway_10092874", "reactome": "R-BTA-140877", "name": "Formation of Fibrin Clot (Clotting Cascade)", "reactions": [ "reaction_10037913", "reaction_10037906", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10090718", "reaction_10071946", "reaction_10090183", "reaction_10037923", "reaction_10037948", "reaction_10090181", "reaction_10037845", "reaction_10038205", "reaction_10037800", "reaction_10037937", "reaction_10090185", "reaction_10037927", "reaction_10037899", "reaction_10038201", "reaction_10037887", "reaction_10037915", "reaction_10037852", "reaction_10091671", "reaction_10038221", "reaction_10038213", "reaction_10037950", "reaction_10037815", "reaction_10091546", "reaction_10038166", "reaction_10071906", "reaction_10037895" ] }, "R-BTA-1474165": { "id": "pathway_10094050", "reactome": "R-BTA-1474165", "name": "Reproduction", "reactions": [ "reaction_10065886", "reaction_10065875", "reaction_10065884", "reaction_10057605", "reaction_10057598", "reaction_10065827", "reaction_10065866" ] }, "R-BTA-9033241": { "id": "pathway_10094954", "reactome": "R-BTA-9033241", "name": "Peroxisomal protein import", "reactions": [ "reaction_10090604", "reaction_10090593" ] }, "R-BTA-71064": { "id": "pathway_10092512", "reactome": "R-BTA-71064", "name": "Lysine catabolism", "reactions": [ "reaction_10045036", "reaction_10051198", "reaction_10077435", "reaction_10077864", "reaction_10076984", "reaction_10076261" ] }, "R-BTA-375165": { "id": "pathway_10093636", "reactome": "R-BTA-375165", "name": "NCAM signaling for neurite out-growth", "reactions": [ "reaction_10047449", "reaction_10047455", "reaction_10047458" ] }, "R-BTA-8866907": { "id": "pathway_10094782", "reactome": "R-BTA-8866907", "name": "Activation of the TFAP2 (AP-2) family of transcription factors", "reactions": [ "reaction_10084911", "reaction_10084922", "reaction_10084895", "reaction_10084881" ] }, "R-BTA-5620924": { "id": "pathway_10094482", "reactome": "R-BTA-5620924", "name": "Intraflagellar transport", "reactions": [ "reaction_10072271" ] }, "R-BTA-165159": { "id": "pathway_10092996", "reactome": "R-BTA-165159", "name": "MTOR signalling", "reactions": [ "reaction_10073851", "reaction_10049894", "reaction_10039200", "reaction_10046588", "reaction_10046572", "reaction_10091741", "reaction_10073853", "reaction_10088496", "reaction_10072902", "reaction_10072900", "reaction_10039127", "reaction_10039155", "reaction_10088493", "reaction_10039059", "reaction_10046583", "reaction_10039209", "reaction_10073844", "reaction_10039160", "reaction_10039180" ] }, "R-BTA-9607240": { "id": "pathway_10094646", "reactome": "R-BTA-9607240", "name": "FLT3 Signaling", "reactions": [ "reaction_10092147", "reaction_10092173", "reaction_10092033", "reaction_10092139", "reaction_10092165", "reaction_10092126", "reaction_10077790", "reaction_10090916", "reaction_10092143", "reaction_10092195", "reaction_10092159", "reaction_10090919", "reaction_10090844", "reaction_10092141", "reaction_10092043", "reaction_10084305", "reaction_10092137", "reaction_10092183", "reaction_10092040", "reaction_10092151", "reaction_10092133" ] }, "R-BTA-977347": { "id": "pathway_10093940", "reactome": "R-BTA-977347", "name": "Serine biosynthesis", "reactions": [ "reaction_10090647", "reaction_10054601", "reaction_10086371", "reaction_10090175", "reaction_10054620", "reaction_10054611", "reaction_10090172" ] }, "R-BTA-196819": { "id": "pathway_10093286", "reactome": "R-BTA-196819", "name": "Vitamin B1 (thiamin) metabolism", "reactions": [ "reaction_10041753", "reaction_10042799" ] }, "R-BTA-111446": { "id": "pathway_10092862", "reactome": "R-BTA-111446", "name": "Activation of BIM and translocation to mitochondria ", "reactions": [ "reaction_10037723", "reaction_10037727" ] }, "R-BTA-74158": { "id": "pathway_10092686", "reactome": "R-BTA-74158", "name": "RNA Polymerase III Transcription", "reactions": [ "reaction_10035854" ] }, "R-BTA-170968": { "id": "pathway_10093102", "reactome": "R-BTA-170968", "name": "Frs2-mediated activation", "reactions": [ "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090944", "reaction_10090954", "reaction_10039711" ] }, "R-BTA-2142850": { "id": "pathway_10094226", "reactome": "R-BTA-2142850", "name": "Hyaluronan biosynthesis and export", "reactions": [ "reaction_10064353" ] }, "R-BTA-75876": { "id": "pathway_10093330", "reactome": "R-BTA-75876", "name": "Synthesis of very long-chain fatty acyl-CoAs", "reactions": [ "reaction_10051252", "reaction_10042961", "reaction_10074353", "reaction_10051261" ] }, "R-BTA-2871837": { "id": "pathway_10093354", "reactome": "R-BTA-2871837", "name": "FCERI mediated NF-kB activation", "reactions": [ "reaction_10066059", "reaction_10066172", "reaction_10066141", "reaction_10066127", "reaction_10066147", "reaction_10043225", "reaction_10066180", "reaction_10066168" ] }, "R-BTA-8956321": { "id": "pathway_10092596", "reactome": "R-BTA-8956321", "name": "Nucleotide salvage", "reactions": [ "reaction_10036306", "reaction_10088624", "reaction_10035435", "reaction_10035426", "reaction_10035020", "reaction_10036308", "reaction_10034989", "reaction_10036649", "reaction_10034980", "reaction_10051215", "reaction_10035444", "reaction_10035479", "reaction_10035007", "reaction_10036614", "reaction_10036001" ] }, "R-BTA-210500": { "id": "pathway_10092502", "reactome": "R-BTA-210500", "name": "Glutamate Neurotransmitter Release Cycle", "reactions": [ "reaction_10044076", "reaction_10044461", "reaction_10033755" ] }, "R-BTA-112043": { "id": "pathway_10092770", "reactome": "R-BTA-112043", "name": "PLC beta mediated events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10037045", "reaction_10049478", "reaction_10036959", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-6798695": { "id": "pathway_10094666", "reactome": "R-BTA-6798695", "name": "Neutrophil degranulation", "reactions": [ "reaction_10080063", "reaction_10078929", "reaction_10080435", "reaction_10079391", "reaction_10080719", "reaction_10079949", "reaction_10079653", "reaction_10079199", "reaction_10081085", "reaction_10081265" ] }, "R-BTA-190371": { "id": "pathway_10093194", "reactome": "R-BTA-190371", "name": "FGFR3b ligand binding and activation", "reactions": [ "reaction_10040761", "reaction_10040779" ] }, "R-BTA-191859": { "id": "pathway_10093230", "reactome": "R-BTA-191859", "name": "snRNP Assembly", "reactions": [ "reaction_10041050", "reaction_10041039" ] }, "R-BTA-173599": { "id": "pathway_10093108", "reactome": "R-BTA-173599", "name": "Formation of the active cofactor, UDP-glucuronate", "reactions": [ "reaction_10039874", "reaction_10039749" ] }, "R-BTA-1660514": { "id": "pathway_10094156", "reactome": "R-BTA-1660514", "name": "Synthesis of PIPs at the Golgi membrane", "reactions": [ "reaction_10060597", "reaction_10060483", "reaction_10060516", "reaction_10060611", "reaction_10060498" ] }, "R-BTA-168643": { "id": "pathway_10093868", "reactome": "R-BTA-168643", "name": "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways", "reactions": [ "reaction_10051836" ] }, "R-BTA-75944": { "id": "pathway_10092976", "reactome": "R-BTA-75944", "name": "Transcription from mitochondrial promoters", "reactions": [ "reaction_10038904" ] }, "R-BTA-69473": { "id": "pathway_10094586", "reactome": "R-BTA-69473", "name": "G2/M DNA damage checkpoint", "reactions": [ "reaction_10074695", "reaction_10074692" ] }, "R-BTA-416700": { "id": "pathway_10093510", "reactome": "R-BTA-416700", "name": "Other semaphorin interactions", "reactions": [ "reaction_10045244", "reaction_10045236" ] }, "R-BTA-933541": { "id": "pathway_10093900", "reactome": "R-BTA-933541", "name": "TRAF6 mediated IRF7 activation", "reactions": [ "reaction_10056088", "reaction_10053048", "reaction_10053046", "reaction_10053058" ] }, "R-BTA-388479": { "id": "pathway_10093566", "reactome": "R-BTA-388479", "name": "Vasopressin-like receptors", "reactions": [ "reaction_10046733", "reaction_10046731", "reaction_10047483" ] }, "R-BTA-2980736": { "id": "pathway_10093532", "reactome": "R-BTA-2980736", "name": "Peptide hormone metabolism", "reactions": [ "reaction_10045736", "reaction_10046723", "reaction_10091056", "reaction_10048461", "reaction_10048429", "reaction_10049392", "reaction_10045744", "reaction_10045696", "reaction_10048380", "reaction_10049385", "reaction_10048407", "reaction_10048465", "reaction_10045694" ] }, "R-BTA-75955": { "id": "pathway_10092814", "reactome": "R-BTA-75955", "name": "RNA Polymerase II Transcription Elongation", "reactions": [ "reaction_10037205", "reaction_10037203" ] }, "R-BTA-71288": { "id": "pathway_10092544", "reactome": "R-BTA-71288", "name": "Creatine metabolism", "reactions": [ "reaction_10033997", "reaction_10042838", "reaction_10042847", "reaction_10034004" ] }, "R-BTA-450531": { "id": "pathway_10093804", "reactome": "R-BTA-450531", "name": "Regulation of mRNA stability by proteins that bind AU-rich elements", "reactions": [ "reaction_10050380", "reaction_10050373", "reaction_10051066", "reaction_10050306", "reaction_10051219", "reaction_10050378", "reaction_10051221", "reaction_10050366", "reaction_10050342", "reaction_10050408", "reaction_10050368", "reaction_10050318", "reaction_10050400" ] }, "R-BTA-5140745": { "id": "pathway_10094414", "reactome": "R-BTA-5140745", "name": "WNT5A-dependent internalization of FZD2, FZD5 and ROR2", "reactions": [ "reaction_10069896" ] }, "R-BTA-69202": { "id": "pathway_10093150", "reactome": "R-BTA-69202", "name": "Cyclin E associated events during G1/S transition ", "reactions": [ "reaction_10040521", "reaction_10083565", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-5610787": { "id": "pathway_10094474", "reactome": "R-BTA-5610787", "name": "Hedgehog 'off' state", "reactions": [ "reaction_10072138", "reaction_10072220", "reaction_10072123", "reaction_10072199", "reaction_10072154", "reaction_10072081" ] }, "R-BTA-8963899": { "id": "pathway_10093458", "reactome": "R-BTA-8963899", "name": "Plasma lipoprotein remodeling", "reactions": [ "reaction_10044547", "reaction_10084509", "reaction_10077487", "reaction_10077489", "reaction_10088982", "reaction_10044666" ] }, "R-BTA-69206": { "id": "pathway_10092408", "reactome": "R-BTA-69206", "name": "G1/S Transition", "reactions": [ "reaction_10033512", "reaction_10040521", "reaction_10083565", "reaction_10033466", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10083558" ] }, "R-BTA-74217": { "id": "pathway_10092634", "reactome": "R-BTA-74217", "name": "Purine salvage", "reactions": [ "reaction_10036306", "reaction_10035435", "reaction_10035426", "reaction_10036308", "reaction_10051215", "reaction_10035444", "reaction_10036001" ] }, "R-BTA-1236973": { "id": "pathway_10094000", "reactome": "R-BTA-1236973", "name": "Cross-presentation of particulate exogenous antigens (phagosomes)", "reactions": [ "reaction_10057004" ] }, "R-BTA-204626": { "id": "pathway_10093390", "reactome": "R-BTA-204626", "name": "Hypusine synthesis from eIF5A-lysine", "reactions": [ "reaction_10043717", "reaction_10043698" ] }, "R-BTA-422356": { "id": "pathway_10093464", "reactome": "R-BTA-422356", "name": "Regulation of insulin secretion", "reactions": [ "reaction_10047765", "reaction_10047809", "reaction_10046642", "reaction_10049346", "reaction_10046623", "reaction_10049351", "reaction_10044634", "reaction_10046630", "reaction_10046648" ] }, "R-BTA-5357801": { "id": "pathway_10092622", "reactome": "R-BTA-5357801", "name": "Programmed Cell Death", "reactions": [ "reaction_10037731", "reaction_10044146", "reaction_10068030", "reaction_10037678", "reaction_10037706", "reaction_10044756", "reaction_10091191", "reaction_10044869", "reaction_10037723", "reaction_10074240", "reaction_10038007", "reaction_10091409", "reaction_10091186", "reaction_10070684", "reaction_10072346", "reaction_10051181", "reaction_10037739", "reaction_10043021", "reaction_10091783", "reaction_10037727", "reaction_10037985", "reaction_10037622", "reaction_10092356", "reaction_10044568", "reaction_10051175", "reaction_10037253", "reaction_10037702", "reaction_10037277", "reaction_10067891", "reaction_10091793", "reaction_10044680", "reaction_10071534", "reaction_10091808", "reaction_10090573", "reaction_10091810", "reaction_10037289", "reaction_10091429", "reaction_10070531", "reaction_10091415", "reaction_10044906", "reaction_10037641", "reaction_10092350", "reaction_10068042", "reaction_10037991", "reaction_10043039", "reaction_10037618", "reaction_10070534", "reaction_10044762", "reaction_10068046", "reaction_10044896", "reaction_10044927", "reaction_10035396", "reaction_10037293", "reaction_10091197", "reaction_10037630", "reaction_10091188", "reaction_10092358", "reaction_10043059", "reaction_10081905", "reaction_10037674", "reaction_10039520", "reaction_10070682", "reaction_10092341", "reaction_10070689", "reaction_10090575", "reaction_10037264", "reaction_10092352", "reaction_10091423", "reaction_10092354", "reaction_10091773", "reaction_10044116", "reaction_10091439", "reaction_10043049", "reaction_10091806", "reaction_10044995", "reaction_10074254", "reaction_10044578", "reaction_10081897", "reaction_10091779", "reaction_10044142", "reaction_10037237", "reaction_10091425", "reaction_10044923", "reaction_10044144", "reaction_10067895" ] }, "R-BTA-1430728": { "id": "pathway_10092458", "reactome": "R-BTA-1430728", "name": "Metabolism", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10066450", "reaction_10080521", "reaction_10088624", "reaction_10060216", "reaction_10082880", "reaction_10036683", "reaction_10041363", "reaction_10066430", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10062697", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10090172", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10053352", "reaction_10090645", "reaction_10040136", "reaction_10041359", "reaction_10044250", "reaction_10071388", "reaction_10076900", "reaction_10083575", "reaction_10060569", "reaction_10036308", "reaction_10063807", "reaction_10082934", "reaction_10065378", "reaction_10058998", "reaction_10059977", "reaction_10038427", "reaction_10039254", "reaction_10036029", "reaction_10034224", "reaction_10041772", "reaction_10080515", "reaction_10050437", "reaction_10051185", "reaction_10063444", "reaction_10087515", "reaction_10039921", "reaction_10044657", "reaction_10060302", "reaction_10038354", "reaction_10063560", "reaction_10064353", "reaction_10052030", "reaction_10083876", "reaction_10061064", "reaction_10071344", "reaction_10044480", "reaction_10041477", "reaction_10060448", "reaction_10034998", "reaction_10064442", "reaction_10034962", "reaction_10041500", "reaction_10047807", "reaction_10036938", "reaction_10061395", "reaction_10076274", "reaction_10064346", "reaction_10039044", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10033620", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10080765", "reaction_10082152", "reaction_10061612", "reaction_10085784", "reaction_10039874", "reaction_10047001", "reaction_10044235", "reaction_10076792", "reaction_10078710", "reaction_10041357", "reaction_10082078", "reaction_10043956", "reaction_10047058", "reaction_10036021", "reaction_10044223", "reaction_10041415", "reaction_10064465", "reaction_10089808", "reaction_10033896", "reaction_10086272", "reaction_10090851", "reaction_10041310", "reaction_10060250", "reaction_10041790", "reaction_10038000", "reaction_10080519", "reaction_10077864", "reaction_10059006", "reaction_10039918", "reaction_10041290", "reaction_10064452", "reaction_10042847", "reaction_10040895", "reaction_10033962", "reaction_10041327", "reaction_10061116", "reaction_10090620", "reaction_10086403", "reaction_10046642", "reaction_10086371", "reaction_10034041", "reaction_10085843", "reaction_10084480", "reaction_10066526", "reaction_10063603", "reaction_10077890", "reaction_10076856", "reaction_10044293", "reaction_10041664", "reaction_10050160", "reaction_10041885", "reaction_10033718", "reaction_10040185", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10041753", "reaction_10034953", "reaction_10063520", "reaction_10060255", "reaction_10064546", "reaction_10083614", "reaction_10090703", "reaction_10082058", "reaction_10088666", "reaction_10088928", "reaction_10043948", "reaction_10091291", "reaction_10085316", "reaction_10035417", "reaction_10041838", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10063803", "reaction_10089721", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10060678", "reaction_10036207", "reaction_10041349", "reaction_10077458", "reaction_10064474", "reaction_10060825", "reaction_10033706", "reaction_10037748", "reaction_10076884", "reaction_10060553", "reaction_10090390", "reaction_10044265", "reaction_10060625", "reaction_10090647", "reaction_10033570", "reaction_10061061", "reaction_10060980", "reaction_10040157", "reaction_10040636", "reaction_10044247", "reaction_10036042", "reaction_10041493", "reaction_10038382", "reaction_10063805", "reaction_10033840", "reaction_10046989", "reaction_10044195", "reaction_10081935", "reaction_10052046", "reaction_10039930", "reaction_10063014", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10081339", "reaction_10041204", "reaction_10085775", "reaction_10044158", "reaction_10076475", "reaction_10047056", "reaction_10060993", "reaction_10062463", "reaction_10083852", "reaction_10077124", "reaction_10041301", "reaction_10066502", "reaction_10039916", "reaction_10076785", "reaction_10041299", "reaction_10076133", "reaction_10048882", "reaction_10035345", "reaction_10041195", "reaction_10090468", "reaction_10054375", "reaction_10041975", "reaction_10083204", "reaction_10044844", "reaction_10060361", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10038895", "reaction_10035464", "reaction_10060228", "reaction_10082068", "reaction_10076806", "reaction_10090394", "reaction_10033770", "reaction_10091727", "reaction_10041208", "reaction_10076485", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10060671", "reaction_10085291", "reaction_10065437", "reaction_10058812", "reaction_10044242", "reaction_10085362", "reaction_10049170", "reaction_10084424", "reaction_10089959", "reaction_10033594", "reaction_10036909", "reaction_10040933", "reaction_10041424", "reaction_10035878", "reaction_10058755", "reaction_10064503", "reaction_10040131", "reaction_10076441", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10033944", "reaction_10033690", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10036256", "reaction_10047065", "reaction_10067648", "reaction_10047019", "reaction_10059016", "reaction_10046630", "reaction_10035865", "reaction_10062655", "reaction_10060983", "reaction_10076254", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10051165", "reaction_10075631", "reaction_10041317", "reaction_10067644", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10035011", "reaction_10039923", "reaction_10040922", "reaction_10060461", "reaction_10089728", "reaction_10088580", "reaction_10090013", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10066528", "reaction_10060231", "reaction_10077453", "reaction_10064516", "reaction_10033849", "reaction_10076984", "reaction_10058894", "reaction_10036220", "reaction_10089795", "reaction_10060041", "reaction_10041962", "reaction_10051215", "reaction_10063018", "reaction_10060614", "reaction_10033778", "reaction_10084694", "reaction_10071722", "reaction_10085352", "reaction_10046992", "reaction_10036267", "reaction_10060986", "reaction_10050169", "reaction_10035863", "reaction_10041817", "reaction_10041323", "reaction_10038060", "reaction_10064393", "reaction_10035786", "reaction_10066416", "reaction_10086336", "reaction_10042940", "reaction_10071763", "reaction_10042799", "reaction_10067733", "reaction_10035911", "reaction_10060600", "reaction_10036258", "reaction_10049004", "reaction_10042915", "reaction_10085798", "reaction_10071909", "reaction_10060590", "reaction_10034013", "reaction_10039049", "reaction_10040115", "reaction_10041437", "reaction_10036692", "reaction_10041671", "reaction_10058916", "reaction_10061251", "reaction_10042657", "reaction_10045036", "reaction_10041277", "reaction_10044211", "reaction_10076281", "reaction_10033638", "reaction_10038336", "reaction_10060429", "reaction_10083369", "reaction_10041878", "reaction_10033788", "reaction_10086033", "reaction_10090015", "reaction_10059035", "reaction_10090379", "reaction_10036001", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10042929", "reaction_10086630", "reaction_10049182", "reaction_10058772", "reaction_10046984", "reaction_10051980", "reaction_10090440", "reaction_10060572", "reaction_10063020", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10063610", "reaction_10085365", "reaction_10065328", "reaction_10040913", "reaction_10049163", "reaction_10065319", "reaction_10054611", "reaction_10061134", "reaction_10077658", "reaction_10048986", "reaction_10045692", "reaction_10063010", "reaction_10036231", "reaction_10058908", "reaction_10035047", "reaction_10041226", "reaction_10061011", "reaction_10090493", "reaction_10041341", "reaction_10041840", "reaction_10040672", "reaction_10061076", "reaction_10035372", "reaction_10091605", "reaction_10066249", "reaction_10080747", "reaction_10060031", "reaction_10067610", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10061122", "reaction_10090460", "reaction_10069948", "reaction_10041111", "reaction_10041170", "reaction_10045043", "reaction_10041824", "reaction_10060264", "reaction_10063420", "reaction_10060476", "reaction_10060234", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10033997", "reaction_10034240", "reaction_10050446", "reaction_10043933", "reaction_10090638", "reaction_10034944", "reaction_10038938", "reaction_10047042", "reaction_10083861", "reaction_10064479", "reaction_10091286", "reaction_10059114", "reaction_10058892", "reaction_10065359", "reaction_10090162", "reaction_10049154", "reaction_10058524", "reaction_10058945", "reaction_10051973", "reaction_10067639", "reaction_10041716", "reaction_10036614", "reaction_10033737", "reaction_10058753", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10033611", "reaction_10033629", "reaction_10035435", "reaction_10059141", "reaction_10033824", "reaction_10060468", "reaction_10033697", "reaction_10033728", "reaction_10044599", "reaction_10091293", "reaction_10061131", "reaction_10041484", "reaction_10059991", "reaction_10085359", "reaction_10054592", "reaction_10066461", "reaction_10092062", "reaction_10035795", "reaction_10054585", "reaction_10041397", "reaction_10063232", "reaction_10088026", "reaction_10035426", "reaction_10086557", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10061052", "reaction_10053348", "reaction_10036664", "reaction_10083800", "reaction_10087455", "reaction_10042922", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10071715", "reaction_10041367", "reaction_10059094", "reaction_10088617", "reaction_10078575", "reaction_10033935", "reaction_10033833", "reaction_10054620", "reaction_10034238", "reaction_10043986", "reaction_10035861", "reaction_10034032", "reaction_10076863", "reaction_10065383", "reaction_10064445", "reaction_10044801", "reaction_10033969", "reaction_10041369", "reaction_10033579", "reaction_10061137", "reaction_10058943", "reaction_10033889", "reaction_10072825", "reaction_10061350", "reaction_10035455", "reaction_10061034", "reaction_10076375", "reaction_10052056", "reaction_10090802", "reaction_10086623", "reaction_10058785", "reaction_10090155", "reaction_10080887", "reaction_10059026", "reaction_10065445", "reaction_10061079", "reaction_10041365", "reaction_10061040", "reaction_10059853", "reaction_10041744", "reaction_10036649", "reaction_10035329", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10044524", "reaction_10064534", "reaction_10060842", "reaction_10060963", "reaction_10040892", "reaction_10092065", "reaction_10073431", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10049351", "reaction_10078393", "reaction_10042838", "reaction_10061113", "reaction_10034980", "reaction_10067622", "reaction_10040120", "reaction_10044218", "reaction_10090382", "reaction_10058774", "reaction_10066576", "reaction_10051261", "reaction_10041353", "reaction_10063530", "reaction_10090631", "reaction_10082143", "reaction_10036306", "reaction_10047765", "reaction_10063456", "reaction_10077444", "reaction_10059851", "reaction_10088867", "reaction_10076130", "reaction_10077435", "reaction_10071727", "reaction_10077004", "reaction_10042906", "reaction_10034140", "reaction_10061037", "reaction_10083115", "reaction_10051676", "reaction_10087442", "reaction_10061067", "reaction_10035812", "reaction_10066471", "reaction_10071712", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10038318", "reaction_10033592", "reaction_10035319", "reaction_10060938", "reaction_10034118", "reaction_10038338", "reaction_10044255", "reaction_10035009", "reaction_10076459", "reaction_10066571", "reaction_10088737", "reaction_10039047", "reaction_10061043", "reaction_10091611", "reaction_10058993", "reaction_10052043", "reaction_10083577", "reaction_10036038", "reaction_10076898", "reaction_10058913", "reaction_10066882", "reaction_10085808", "reaction_10043978", "reaction_10063430", "reaction_10063485", "reaction_10063442", "reaction_10091289", "reaction_10059984", "reaction_10059856", "reaction_10090175", "reaction_10034215", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10053266", "reaction_10078701", "reaction_10034924", "reaction_10036685", "reaction_10041319", "reaction_10041179", "reaction_10043980", "reaction_10060829", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10044232", "reaction_10083211", "reaction_10078402", "reaction_10071754", "reaction_10066619", "reaction_10090681", "reaction_10090679", "reaction_10044477", "reaction_10064491", "reaction_10071643", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10065225", "reaction_10041377", "reaction_10042961", "reaction_10041756", "reaction_10041172", "reaction_10035354", "reaction_10082948", "reaction_10044784", "reaction_10041486", "reaction_10038371", "reaction_10058834", "reaction_10043885", "reaction_10033681", "reaction_10058874", "reaction_10060827", "reaction_10090854", "reaction_10060295", "reaction_10041386", "reaction_10044182", "reaction_10059858", "reaction_10040881", "reaction_10066585", "reaction_10060109", "reaction_10040688", "reaction_10034206", "reaction_10035339", "reaction_10033912", "reaction_10042801", "reaction_10058896", "reaction_10090772", "reaction_10076261", "reaction_10044225", "reaction_10061014", "reaction_10076815", "reaction_10065371", "reaction_10039865", "reaction_10039604", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10077758", "reaction_10033797", "reaction_10035308", "reaction_10089850", "reaction_10041799", "reaction_10066574", "reaction_10041193", "reaction_10090498", "reaction_10067240", "reaction_10090510", "reaction_10040663", "reaction_10076974", "reaction_10090696", "reaction_10045050", "reaction_10058514", "reaction_10053350", "reaction_10048978", "reaction_10060498", "reaction_10063532", "reaction_10035342", "reaction_10068748", "reaction_10065386", "reaction_10034927", "reaction_10047022", "reaction_10041293", "reaction_10064595", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10061642", "reaction_10091598", "reaction_10034971", "reaction_10060917", "reaction_10074353", "reaction_10090384", "reaction_10075404", "reaction_10085788", "reaction_10058975", "reaction_10061031", "reaction_10041412", "reaction_10059847", "reaction_10044794", "reaction_10053298", "reaction_10034231", "reaction_10080517", "reaction_10083389", "reaction_10040129", "reaction_10063564", "reaction_10067634", "reaction_10085780", "reaction_10035444", "reaction_10057792", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10058511", "reaction_10078366", "reaction_10090489", "reaction_10059000", "reaction_10044167", "reaction_10034175", "reaction_10064578", "reaction_10040112", "reaction_10035020", "reaction_10059951", "reaction_10076799", "reaction_10034989", "reaction_10085853", "reaction_10038238", "reaction_10058910", "reaction_10035038", "reaction_10065455", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10040098", "reaction_10062508", "reaction_10060556", "reaction_10052027", "reaction_10063413", "reaction_10034043", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10042655", "reaction_10086064", "reaction_10063437", "reaction_10081346", "reaction_10062674", "reaction_10090867", "reaction_10036012", "reaction_10036907", "reaction_10038647", "reaction_10090464", "reaction_10058751", "reaction_10041955", "reaction_10090671", "reaction_10088926", "reaction_10066569", "reaction_10040147", "reaction_10060550", "reaction_10040682", "reaction_10041197", "reaction_10073477", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10088571", "reaction_10035958", "reaction_10066247", "reaction_10038918", "reaction_10044204", "reaction_10064581", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10063477", "reaction_10065441", "reaction_10033806", "reaction_10044216", "reaction_10040122", "reaction_10088898", "reaction_10084129", "reaction_10081984", "reaction_10057079", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10064591", "reaction_10060285", "reaction_10041831", "reaction_10061119", "reaction_10090474", "reaction_10043984", "reaction_10068755", "reaction_10051570", "reaction_10035332", "reaction_10051198", "reaction_10063448", "reaction_10034138", "reaction_10090797", "reaction_10066587", "reaction_10035007", "reaction_10046968", "reaction_10064439", "reaction_10033671", "reaction_10036238", "reaction_10046648", "reaction_10060021", "reaction_10085855", "reaction_10039887", "reaction_10077777", "reaction_10083926", "reaction_10065763", "reaction_10041297", "reaction_10036903", "reaction_10073438", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10089782", "reaction_10035029", "reaction_10034166", "reaction_10058880", "reaction_10063216", "reaction_10036209", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10035977", "reaction_10041781", "reaction_10083547", "reaction_10041284", "reaction_10051589", "reaction_10060634", "reaction_10040030", "reaction_10035481", "reaction_10036247", "reaction_10060597", "reaction_10034004", "reaction_10090508", "reaction_10062701", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10066401", "reaction_10041321", "reaction_10038380", "reaction_10090504", "reaction_10063508", "reaction_10081928", "reaction_10066444", "reaction_10033953", "reaction_10090392", "reaction_10038340", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10086469", "reaction_10041808", "reaction_10038942", "reaction_10066458", "reaction_10064597", "reaction_10061084", "reaction_10033561", "reaction_10053361", "reaction_10054601", "reaction_10084526", "reaction_10063428", "reaction_10061125", "reaction_10034157", "reaction_10063022", "reaction_10040021", "reaction_10060207", "reaction_10060252", "reaction_10051075", "reaction_10085381", "reaction_10039242", "reaction_10035479", "reaction_10035698", "reaction_10076903", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10042648", "reaction_10071729", "reaction_10044739", "reaction_10041721", "reaction_10040645", "reaction_10063249", "reaction_10060518", "reaction_10063510", "reaction_10061651", "reaction_10061017", "reaction_10071717", "reaction_10085340", "reaction_10060741", "reaction_10043971", "reaction_10065369", "reaction_10044776", "reaction_10058809", "reaction_10065381", "reaction_10044835", "reaction_10085185", "reaction_10078529", "reaction_10033755", "reaction_10086543", "reaction_10038231", "reaction_10041347", "reaction_10064355", "reaction_10040654", "reaction_10043924", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10034071", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10067254", "reaction_10046623", "reaction_10043917", "reaction_10089230", "reaction_10044851", "reaction_10065760", "reaction_10080756", "reaction_10050637", "reaction_10061024", "reaction_10063633", "reaction_10040152", "reaction_10061006", "reaction_10044270", "reaction_10039240", "reaction_10083864", "reaction_10045029", "reaction_10067425", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10090856", "reaction_10041373", "reaction_10033868", "reaction_10060535", "reaction_10086748", "reaction_10054395", "reaction_10063440", "reaction_10035838", "reaction_10067247", "reaction_10059014", "reaction_10082136", "reaction_10077496", "reaction_10043910", "reaction_10049346", "reaction_10088744", "reaction_10060685", "reaction_10041894", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10063801", "reaction_10077835", "reaction_10083889", "reaction_10047044", "reaction_10090799", "reaction_10065223", "reaction_10044828", "reaction_10058923", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10049161", "reaction_10066473", "reaction_10041737", "reaction_10085024", "reaction_10041379", "reaction_10072894", "reaction_10066602", "reaction_10044837", "reaction_10070971", "reaction_10060012", "reaction_10061046", "reaction_10090386", "reaction_10058877", "reaction_10047809", "reaction_10090611", "reaction_10083092", "reaction_10081977", "reaction_10076450", "reaction_10071924", "reaction_10057787", "reaction_10086248", "reaction_10061402", "reaction_10036229", "reaction_10035453", "reaction_10040107", "reaction_10060956", "reaction_10059121", "reaction_10061049", "reaction_10034921", "reaction_10040924", "reaction_10060951", "reaction_10076360", "reaction_10040117", "reaction_10083873", "reaction_10057684", "reaction_10041502", "reaction_10038316", "reaction_10058980", "reaction_10047033", "reaction_10057032", "reaction_10062984", "reaction_10044533", "reaction_10061128", "reaction_10058990", "reaction_10085806", "reaction_10057023", "reaction_10033716", "reaction_10059021", "reaction_10060514", "reaction_10044634", "reaction_10086550", "reaction_10060293", "reaction_10060611", "reaction_10033979", "reaction_10085374", "reaction_10052040", "reaction_10091613", "reaction_10064584", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10044275", "reaction_10059860", "reaction_10059961", "reaction_10048995", "reaction_10064593", "reaction_10049116", "reaction_10090822", "reaction_10086750", "reaction_10053363", "reaction_10060316", "reaction_10036928", "reaction_10090819", "reaction_10058722", "reaction_10077001", "reaction_10065362", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10076406", "reaction_10081349", "reaction_10076468", "reaction_10088019", "reaction_10041335", "reaction_10077751", "reaction_10038320", "reaction_10060218", "reaction_10064511", "reaction_10043964", "reaction_10042936", "reaction_10076144", "reaction_10033988", "reaction_10082889", "reaction_10090774", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10063586", "reaction_10041217", "reaction_10041765", "reaction_10044260", "reaction_10059150", "reaction_10077793", "reaction_10091936", "reaction_10064391" ] }, "R-BTA-975957": { "id": "pathway_10093896", "reactome": "R-BTA-975957", "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "reactions": [ "reaction_10053044" ] }, "R-BTA-912631": { "id": "pathway_10093882", "reactome": "R-BTA-912631", "name": "Regulation of signaling by CBL", "reactions": [ "reaction_10052323", "reaction_10052302", "reaction_10052294" ] }, "R-BTA-392170": { "id": "pathway_10093640", "reactome": "R-BTA-392170", "name": "ADP signalling through P2Y purinoceptor 12", "reactions": [ "reaction_10047857", "reaction_10047475" ] }, "R-BTA-210455": { "id": "pathway_10092494", "reactome": "R-BTA-210455", "name": "Astrocytic Glutamate-Glutamine Uptake And Metabolism", "reactions": [ "reaction_10033746", "reaction_10044086" ] }, "R-BTA-199220": { "id": "pathway_10093284", "reactome": "R-BTA-199220", "name": "Vitamin B5 (pantothenate) metabolism", "reactions": [ "reaction_10042648", "reaction_10041756", "reaction_10042655", "reaction_10041765", "reaction_10041744", "reaction_10041737" ] }, "R-BTA-202403": { "id": "pathway_10093350", "reactome": "R-BTA-202403", "name": "TCR signaling", "reactions": [ "reaction_10043262", "reaction_10043219", "reaction_10043212", "reaction_10043302", "reaction_10043300", "reaction_10043298", "reaction_10043193", "reaction_10043270", "reaction_10043304", "reaction_10043252", "reaction_10043244", "reaction_10043241", "reaction_10043225", "reaction_10043182", "reaction_10043274" ] }, "R-BTA-373755": { "id": "pathway_10093512", "reactome": "R-BTA-373755", "name": "Semaphorin interactions", "reactions": [ "reaction_10045244", "reaction_10047753", "reaction_10047735", "reaction_10047659", "reaction_10047618", "reaction_10047717", "reaction_10047763", "reaction_10045236" ] }, "R-BTA-8953854": { "id": "pathway_10092702", "reactome": "R-BTA-8953854", "name": "Metabolism of RNA", "reactions": [ "reaction_10049230", "reaction_10050342", "reaction_10049232", "reaction_10036003", "reaction_10050380", "reaction_10036917", "reaction_10050306", "reaction_10050366", "reaction_10050408", "reaction_10052963", "reaction_10050373", "reaction_10053044", "reaction_10050378", "reaction_10051221", "reaction_10050368", "reaction_10050318", "reaction_10036076", "reaction_10036915", "reaction_10041050", "reaction_10051066", "reaction_10041039", "reaction_10051219", "reaction_10036052", "reaction_10050400", "reaction_10036080" ] }, "R-BTA-210745": { "id": "pathway_10093426", "reactome": "R-BTA-210745", "name": "Regulation of gene expression in beta cells", "reactions": [ "reaction_10044090" ] }, "R-BTA-8939211": { "id": "pathway_10094820", "reactome": "R-BTA-8939211", "name": "ESR-mediated signaling", "reactions": [ "reaction_10091151", "reaction_10091275", "reaction_10091260", "reaction_10086662", "reaction_10091158", "reaction_10091118", "reaction_10092314", "reaction_10091271", "reaction_10091267", "reaction_10091115", "reaction_10089761", "reaction_10090712", "reaction_10091156" ] }, "R-BTA-167044": { "id": "pathway_10093106", "reactome": "R-BTA-167044", "name": "Signalling to RAS", "reactions": [ "reaction_10039736", "reaction_10040570", "reaction_10074879" ] }, "R-BTA-76061": { "id": "pathway_10092682", "reactome": "R-BTA-76061", "name": "RNA Polymerase III Transcription Initiation From Type 1 Promoter", "reactions": [ "reaction_10035854" ] }, "R-BTA-111933": { "id": "pathway_10092784", "reactome": "R-BTA-111933", "name": "Calmodulin induced events", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981" ] }, "R-BTA-5683826": { "id": "pathway_10093684", "reactome": "R-BTA-5683826", "name": "Surfactant metabolism", "reactions": [ "reaction_10074833", "reaction_10091120", "reaction_10075095", "reaction_10075105", "reaction_10048761", "reaction_10074707", "reaction_10075125", "reaction_10091124", "reaction_10088922", "reaction_10048003", "reaction_10075086", "reaction_10077947", "reaction_10074857", "reaction_10074686", "reaction_10075084", "reaction_10075019", "reaction_10074869", "reaction_10074863", "reaction_10075023" ] }, "R-BTA-427652": { "id": "pathway_10093720", "reactome": "R-BTA-427652", "name": "Sodium-coupled phosphate cotransporters", "reactions": [ "reaction_10048761", "reaction_10048754", "reaction_10048747" ] }, "R-BTA-2161517": { "id": "pathway_10094234", "reactome": "R-BTA-2161517", "name": "Abacavir transmembrane transport", "reactions": [ "reaction_10064439" ] }, "R-BTA-8849175": { "id": "pathway_10094896", "reactome": "R-BTA-8849175", "name": "Threonine catabolism", "reactions": [ "reaction_10090162", "reaction_10090155" ] }, "R-BTA-2559583": { "id": "pathway_10093054", "reactome": "R-BTA-2559583", "name": "Cellular Senescence", "reactions": [ "reaction_10066630", "reaction_10066870", "reaction_10050192", "reaction_10076298", "reaction_10069684", "reaction_10074429", "reaction_10040355", "reaction_10088964", "reaction_10050208", "reaction_10068899", "reaction_10078369", "reaction_10039508", "reaction_10050231", "reaction_10066786", "reaction_10050256", "reaction_10066876", "reaction_10050218", "reaction_10076341", "reaction_10074446", "reaction_10076343", "reaction_10074453", "reaction_10066857", "reaction_10066779", "reaction_10068854", "reaction_10066832", "reaction_10066873", "reaction_10041950", "reaction_10068959", "reaction_10074431" ] }, "R-BTA-1234176": { "id": "pathway_10093988", "reactome": "R-BTA-1234176", "name": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha", "reactions": [ "reaction_10056688", "reaction_10056719", "reaction_10056754", "reaction_10056757", "reaction_10056759", "reaction_10056761", "reaction_10056737" ] }, "R-BTA-198765": { "id": "pathway_10093302", "reactome": "R-BTA-198765", "name": "Signalling to ERK5", "reactions": [ "reaction_10041917" ] }, "R-BTA-8979227": { "id": "pathway_10092674", "reactome": "R-BTA-8979227", "name": "Triglyceride metabolism", "reactions": [ "reaction_10083544", "reaction_10035795", "reaction_10035838", "reaction_10076847", "reaction_10080887", "reaction_10071388", "reaction_10035829", "reaction_10083547" ] }, "R-BTA-977444": { "id": "pathway_10093096", "reactome": "R-BTA-977444", "name": "GABA B receptor activation", "reactions": [ "reaction_10039651", "reaction_10039676", "reaction_10039653", "reaction_10039664" ] }, "R-BTA-193704": { "id": "pathway_10093260", "reactome": "R-BTA-193704", "name": "p75 NTR receptor-mediated signalling", "reactions": [ "reaction_10043744", "reaction_10043753", "reaction_10043778", "reaction_10043739", "reaction_10041333", "reaction_10041470", "reaction_10043877" ] }, "R-BTA-5607764": { "id": "pathway_10094470", "reactome": "R-BTA-5607764", "name": "CLEC7A (Dectin-1) signaling", "reactions": [ "reaction_10072053", "reaction_10072045", "reaction_10072032", "reaction_10072015", "reaction_10072002", "reaction_10072006", "reaction_10071948", "reaction_10072057", "reaction_10072061", "reaction_10072022", "reaction_10072030", "reaction_10071975", "reaction_10072011", "reaction_10071982" ] }, "R-BTA-629594": { "id": "pathway_10093846", "reactome": "R-BTA-629594", "name": "Highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051523", "reaction_10051521" ] }, "R-BTA-427359": { "id": "pathway_10093716", "reactome": "R-BTA-427359", "name": "SIRT1 negatively regulates rRNA expression", "reactions": [ "reaction_10048717", "reaction_10048720" ] }, "R-BTA-2028269": { "id": "pathway_10094198", "reactome": "R-BTA-2028269", "name": "Signaling by Hippo", "reactions": [ "reaction_10063317", "reaction_10063554", "reaction_10063380", "reaction_10063568", "reaction_10063342", "reaction_10063338", "reaction_10063305", "reaction_10063382", "reaction_10063550", "reaction_10063544", "reaction_10063556", "reaction_10063329", "reaction_10063534", "reaction_10063408", "reaction_10063346", "reaction_10063319" ] }, "R-BTA-190239": { "id": "pathway_10093190", "reactome": "R-BTA-190239", "name": "FGFR3 ligand binding and activation", "reactions": [ "reaction_10040753", "reaction_10040782", "reaction_10040761", "reaction_10083933", "reaction_10040779", "reaction_10083935" ] }, "R-BTA-69273": { "id": "pathway_10093086", "reactome": "R-BTA-69273", "name": "Cyclin A/B1/B2 associated events during G2/M transition", "reactions": [ "reaction_10039612", "reaction_10039614" ] }, "R-BTA-2559586": { "id": "pathway_10094380", "reactome": "R-BTA-2559586", "name": "DNA Damage/Telomere Stress Induced Senescence", "reactions": [ "reaction_10068854", "reaction_10078369", "reaction_10076298", "reaction_10069684", "reaction_10076341", "reaction_10074446", "reaction_10076343", "reaction_10068959", "reaction_10074453", "reaction_10074429", "reaction_10074431" ] }, "R-BTA-8951936": { "id": "pathway_10094844", "reactome": "R-BTA-8951936", "name": "RUNX3 regulates p14-ARF", "reactions": [ "reaction_10088006", "reaction_10087910", "reaction_10087900", "reaction_10087997", "reaction_10087889" ] }, "R-BTA-196807": { "id": "pathway_10093292", "reactome": "R-BTA-196807", "name": "Nicotinate metabolism", "reactions": [ "reaction_10071643", "reaction_10085365", "reaction_10088666", "reaction_10085374", "reaction_10085352", "reaction_10086623", "reaction_10065210", "reaction_10085362", "reaction_10041817", "reaction_10049170", "reaction_10086750", "reaction_10085359", "reaction_10081984", "reaction_10042915", "reaction_10081977", "reaction_10041824", "reaction_10041831", "reaction_10041808", "reaction_10082143", "reaction_10088867", "reaction_10042906", "reaction_10086748", "reaction_10086630" ] }, "R-BTA-168898": { "id": "pathway_10093002", "reactome": "R-BTA-168898", "name": "Toll-like Receptor Cascades", "reactions": [ "reaction_10050192", "reaction_10050196", "reaction_10040197", "reaction_10039481", "reaction_10085369", "reaction_10050208", "reaction_10060783", "reaction_10039560", "reaction_10060759", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10050218", "reaction_10060773", "reaction_10081905", "reaction_10081510", "reaction_10091739", "reaction_10039217", "reaction_10050254", "reaction_10053046", "reaction_10041950", "reaction_10081506", "reaction_10053048", "reaction_10043488", "reaction_10060785", "reaction_10065894" ] }, "R-BTA-165160": { "id": "pathway_10092952", "reactome": "R-BTA-165160", "name": "PDE3B signalling", "reactions": [ "reaction_10038450" ] }, "R-BTA-390247": { "id": "pathway_10093596", "reactome": "R-BTA-390247", "name": "Beta-oxidation of very long chain fatty acids", "reactions": [ "reaction_10082880", "reaction_10047058", "reaction_10075576", "reaction_10047053", "reaction_10077784", "reaction_10054592" ] }, "R-BTA-114452": { "id": "pathway_10092858", "reactome": "R-BTA-114452", "name": "Activation of BH3-only proteins", "reactions": [ "reaction_10037723", "reaction_10037739", "reaction_10037702", "reaction_10037727", "reaction_10037674", "reaction_10037678", "reaction_10037630", "reaction_10037706" ] }, "R-BTA-69615": { "id": "pathway_10092448", "reactome": "R-BTA-69615", "name": "G1/S DNA Damage Checkpoints", "reactions": [ "reaction_10081470", "reaction_10033535", "reaction_10076341", "reaction_10078408" ] }, "R-BTA-70370": { "id": "pathway_10092464", "reactome": "R-BTA-70370", "name": "Galactose catabolism", "reactions": [ "reaction_10033594", "reaction_10033579" ] }, "R-BTA-3270619": { "id": "pathway_10094210", "reactome": "R-BTA-3270619", "name": "IRF3-mediated induction of type I IFN", "reactions": [ "reaction_10065388", "reaction_10063376", "reaction_10065402", "reaction_10065407" ] }, "R-BTA-6803204": { "id": "pathway_10094668", "reactome": "R-BTA-6803204", "name": "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release", "reactions": [ "reaction_10081326", "reaction_10080457", "reaction_10081305", "reaction_10081323" ] }, "R-BTA-417957": { "id": "pathway_10093658", "reactome": "R-BTA-417957", "name": "P2Y receptors", "reactions": [ "reaction_10047866", "reaction_10047870", "reaction_10047868", "reaction_10047862", "reaction_10047864", "reaction_10047851", "reaction_10047853", "reaction_10047989", "reaction_10047857", "reaction_10090956", "reaction_10047860" ] }, "R-BTA-1474244": { "id": "pathway_10093318", "reactome": "R-BTA-1474244", "name": "Extracellular matrix organization", "reactions": [ "reaction_10087587", "reaction_10069313", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10065929", "reaction_10064649", "reaction_10076984", "reaction_10059787", "reaction_10062071", "reaction_10059651", "reaction_10059598", "reaction_10063839", "reaction_10058705", "reaction_10059869", "reaction_10059702", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10059533", "reaction_10064705", "reaction_10064953", "reaction_10087543", "reaction_10087626", "reaction_10059674", "reaction_10059913", "reaction_10044515", "reaction_10064435", "reaction_10059918", "reaction_10060191", "reaction_10058193", "reaction_10065292", "reaction_10060187", "reaction_10062377", "reaction_10064959", "reaction_10058561", "reaction_10065691", "reaction_10065336", "reaction_10065819", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10065300", "reaction_10087589", "reaction_10087324", "reaction_10059923", "reaction_10065751", "reaction_10068885", "reaction_10064337", "reaction_10065555", "reaction_10069412", "reaction_10061787", "reaction_10059902", "reaction_10059744", "reaction_10060003", "reaction_10059441", "reaction_10087567", "reaction_10059689", "reaction_10059731", "reaction_10042253", "reaction_10087569", "reaction_10065435", "reaction_10059804", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10064437", "reaction_10087579" ] }, "R-BTA-5654720": { "id": "pathway_10094542", "reactome": "R-BTA-5654720", "name": "PI-3K cascade:FGFR4", "reactions": [ "reaction_10073237", "reaction_10073192", "reaction_10073240" ] }, "R-BTA-166520": { "id": "pathway_10093018", "reactome": "R-BTA-166520", "name": "Signaling by NTRKs", "reactions": [ "reaction_10090994", "reaction_10039272", "reaction_10043315", "reaction_10040489", "reaction_10041917", "reaction_10041869", "reaction_10090666", "reaction_10039601", "reaction_10039736", "reaction_10041851", "reaction_10040570", "reaction_10039270", "reaction_10090727", "reaction_10042826", "reaction_10039581", "reaction_10040684", "reaction_10090949", "reaction_10039697", "reaction_10039690", "reaction_10090954", "reaction_10074879", "reaction_10090675", "reaction_10039592", "reaction_10041950", "reaction_10090944", "reaction_10090722", "reaction_10043488", "reaction_10039711", "reaction_10040495" ] }, "R-BTA-211957": { "id": "pathway_10092688", "reactome": "R-BTA-211957", "name": "Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2", "reactions": [ "reaction_10035861", "reaction_10035865" ] }, "R-BTA-2029485": { "id": "pathway_10093298", "reactome": "R-BTA-2029485", "name": "Role of phospholipids in phagocytosis", "reactions": [ "reaction_10063368", "reaction_10041863" ] }, "R-BTA-212676": { "id": "pathway_10094444", "reactome": "R-BTA-212676", "name": "Dopamine Neurotransmitter Release Cycle", "reactions": [ "reaction_10071437" ] }, "R-BTA-174411": { "id": "pathway_10095016", "reactome": "R-BTA-174411", "name": "Polymerase switching on the C-strand of the telomere", "reactions": [ "reaction_10091663" ] }, "R-BTA-194306": { "id": "pathway_10093276", "reactome": "R-BTA-194306", "name": "Neurophilin interactions with VEGF and VEGFR", "reactions": [ "reaction_10041657" ] }, "R-BTA-173623": { "id": "pathway_10093110", "reactome": "R-BTA-173623", "name": "Classical antibody-mediated complement activation", "reactions": [ "reaction_10039782", "reaction_10039778" ] }, "R-BTA-73621": { "id": "pathway_10092590", "reactome": "R-BTA-73621", "name": "Pyrimidine catabolism", "reactions": [ "reaction_10034953", "reaction_10036267", "reaction_10036258", "reaction_10035009", "reaction_10036209", "reaction_10035011", "reaction_10034962", "reaction_10036229", "reaction_10036247", "reaction_10035481" ] }, "R-BTA-2243919": { "id": "pathway_10094310", "reactome": "R-BTA-2243919", "name": "Crosslinking of collagen fibrils", "reactions": [ "reaction_10065929" ] }, "R-BTA-8953750": { "id": "pathway_10094856", "reactome": "R-BTA-8953750", "name": "Transcriptional Regulation by E2F6", "reactions": [ "reaction_10089578", "reaction_10089574", "reaction_10088596", "reaction_10088584", "reaction_10088554", "reaction_10088564" ] }, "R-BTA-499943": { "id": "pathway_10092546", "reactome": "R-BTA-499943", "name": "Interconversion of nucleotide di- and triphosphates", "reactions": [ "reaction_10035047", "reaction_10035029", "reaction_10034166", "reaction_10082948", "reaction_10036683", "reaction_10034971", "reaction_10034998", "reaction_10051075", "reaction_10077890", "reaction_10036692", "reaction_10035038", "reaction_10035698", "reaction_10036938", "reaction_10036685" ] }, "R-BTA-9020265": { "id": "pathway_10094916", "reactome": "R-BTA-9020265", "name": "Biosynthesis of aspirin-triggered D-series resolvins", "reactions": [ "reaction_10090388" ] }, "R-BTA-5625970": { "id": "pathway_10094498", "reactome": "R-BTA-5625970", "name": "RHO GTPases activate KTN1", "reactions": [ "reaction_10073842", "reaction_10072515" ] }, "R-BTA-2187338": { "id": "pathway_10092628", "reactome": "R-BTA-2187338", "name": "Visual phototransduction", "reactions": [ "reaction_10065683", "reaction_10065597", "reaction_10035596", "reaction_10054382", "reaction_10054404", "reaction_10065644", "reaction_10035406", "reaction_10065604", "reaction_10065675", "reaction_10065664", "reaction_10088914", "reaction_10065944", "reaction_10035558", "reaction_10091560", "reaction_10091558", "reaction_10065687", "reaction_10065445", "reaction_10065673", "reaction_10066247", "reaction_10065437", "reaction_10054393", "reaction_10065441", "reaction_10066249", "reaction_10070971", "reaction_10069948", "reaction_10065679", "reaction_10065606", "reaction_10035619", "reaction_10077751", "reaction_10077744", "reaction_10065940", "reaction_10065677", "reaction_10035579", "reaction_10065808", "reaction_10065646", "reaction_10054375", "reaction_10054395" ] }, "R-BTA-110312": { "id": "pathway_10092760", "reactome": "R-BTA-110312", "name": "Translesion synthesis by REV1", "reactions": [ "reaction_10036853", "reaction_10036844" ] }, "R-BTA-5250913": { "id": "pathway_10094438", "reactome": "R-BTA-5250913", "name": "Positive epigenetic regulation of rRNA expression", "reactions": [ "reaction_10071065" ] }, "R-BTA-9034013": { "id": "pathway_10094962", "reactome": "R-BTA-9034013", "name": "NTF3 activates NTRK3 signaling", "reactions": [ "reaction_10090666" ] }, "R-BTA-3134975": { "id": "pathway_10094188", "reactome": "R-BTA-3134975", "name": "Regulation of innate immune responses to cytosolic DNA", "reactions": [ "reaction_10066536", "reaction_10066551", "reaction_10061502" ] }, "R-BTA-264870": { "id": "pathway_10093338", "reactome": "R-BTA-264870", "name": "Caspase-mediated cleavage of cytoskeletal proteins", "reactions": [ "reaction_10044756", "reaction_10044762", "reaction_10043049", "reaction_10043059", "reaction_10043021" ] }, "R-BTA-5218900": { "id": "pathway_10094364", "reactome": "R-BTA-5218900", "name": "CASP8 activity is inhibited", "reactions": [ "reaction_10068030", "reaction_10074240" ] }, "R-BTA-975574": { "id": "pathway_10093932", "reactome": "R-BTA-975574", "name": "Reactions specific to the hybrid N-glycan synthesis pathway", "reactions": [ "reaction_10054474" ] }, "R-BTA-6798163": { "id": "pathway_10094136", "reactome": "R-BTA-6798163", "name": "Choline catabolism", "reactions": [ "reaction_10060275", "reaction_10078582", "reaction_10078575" ] }, "R-BTA-6811438": { "id": "pathway_10094706", "reactome": "R-BTA-6811438", "name": "Intra-Golgi traffic", "reactions": [ "reaction_10083458", "reaction_10083767", "reaction_10083451", "reaction_10083425", "reaction_10083056" ] }, "R-BTA-69231": { "id": "pathway_10093136", "reactome": "R-BTA-69231", "name": "Cyclin D associated events in G1", "reactions": [ "reaction_10056602", "reaction_10056616", "reaction_10087394", "reaction_10087487", "reaction_10057821", "reaction_10057816", "reaction_10087385", "reaction_10040355", "reaction_10087503" ] }, "R-BTA-453279": { "id": "pathway_10092410", "reactome": "R-BTA-453279", "name": "Mitotic G1 phase and G1/S transition", "reactions": [ "reaction_10057804", "reaction_10040542", "reaction_10040355", "reaction_10087503", "reaction_10033512", "reaction_10057812", "reaction_10087487", "reaction_10033466", "reaction_10057816", "reaction_10040576", "reaction_10040503", "reaction_10057808", "reaction_10056602", "reaction_10040521", "reaction_10087394", "reaction_10057821", "reaction_10083558", "reaction_10087385", "reaction_10056616", "reaction_10083565", "reaction_10057800" ] }, "R-BTA-8856828": { "id": "pathway_10094780", "reactome": "R-BTA-8856828", "name": "Clathrin-mediated endocytosis", "reactions": [ "reaction_10085313", "reaction_10084824", "reaction_10084757", "reaction_10091753", "reaction_10085134", "reaction_10084822", "reaction_10085264", "reaction_10084819", "reaction_10085166", "reaction_10085116" ] }, "R-BTA-72613": { "id": "pathway_10092578", "reactome": "R-BTA-72613", "name": "Eukaryotic Translation Initiation", "reactions": [ "reaction_10034855", "reaction_10038082", "reaction_10034365", "reaction_10034383", "reaction_10034387", "reaction_10034905" ] }, "R-BTA-8956319": { "id": "pathway_10092592", "reactome": "R-BTA-8956319", "name": "Nucleobase catabolism", "reactions": [ "reaction_10034953", "reaction_10035464", "reaction_10065359", "reaction_10083926", "reaction_10065763", "reaction_10035455", "reaction_10065328", "reaction_10065319", "reaction_10065369", "reaction_10088571", "reaction_10065381", "reaction_10036231", "reaction_10036267", "reaction_10083889", "reaction_10035009", "reaction_10036209", "reaction_10036207", "reaction_10036247", "reaction_10035481", "reaction_10065378", "reaction_10036258", "reaction_10065362", "reaction_10065371", "reaction_10036256", "reaction_10065760", "reaction_10036229", "reaction_10035453", "reaction_10083864", "reaction_10083876", "reaction_10083852", "reaction_10035011", "reaction_10083873", "reaction_10083861", "reaction_10034962", "reaction_10065383", "reaction_10036238", "reaction_10065386" ] }, "R-BTA-166166": { "id": "pathway_10093072", "reactome": "R-BTA-166166", "name": "MyD88-independent TLR4 cascade ", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-2559580": { "id": "pathway_10093052", "reactome": "R-BTA-2559580", "name": "Oxidative Stress Induced Senescence", "reactions": [ "reaction_10066876", "reaction_10050208", "reaction_10066870", "reaction_10050192", "reaction_10066832", "reaction_10050218", "reaction_10066873", "reaction_10039508", "reaction_10050231", "reaction_10066857", "reaction_10050256", "reaction_10040355", "reaction_10066786", "reaction_10066779", "reaction_10088964" ] }, "R-BTA-163560": { "id": "pathway_10094442", "reactome": "R-BTA-163560", "name": "Triglyceride catabolism", "reactions": [ "reaction_10083547", "reaction_10083544", "reaction_10071388" ] }, "R-BTA-5654741": { "id": "pathway_10093192", "reactome": "R-BTA-5654741", "name": "Signaling by FGFR3", "reactions": [ "reaction_10073014", "reaction_10072946", "reaction_10073147", "reaction_10057327", "reaction_10073019", "reaction_10073145", "reaction_10040779", "reaction_10073234", "reaction_10057314", "reaction_10057329", "reaction_10059156", "reaction_10053082", "reaction_10083935", "reaction_10073021", "reaction_10073011", "reaction_10057318", "reaction_10072944", "reaction_10040753", "reaction_10073152", "reaction_10083933", "reaction_10073140", "reaction_10087376", "reaction_10073244", "reaction_10072913", "reaction_10073159", "reaction_10057323", "reaction_10073156", "reaction_10040761", "reaction_10057337", "reaction_10073215", "reaction_10040782", "reaction_10057302" ] }, "R-BTA-5654727": { "id": "pathway_10093908", "reactome": "R-BTA-5654727", "name": "Negative regulation of FGFR2 signaling", "reactions": [ "reaction_10059156", "reaction_10057327", "reaction_10057318", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10073242", "reaction_10057337", "reaction_10053082", "reaction_10073208", "reaction_10057302" ] }, "R-BTA-68962": { "id": "pathway_10092406", "reactome": "R-BTA-68962", "name": "Activation of the pre-replicative complex", "reactions": [ "reaction_10033512", "reaction_10033466" ] }, "R-BTA-177162": { "id": "pathway_10093130", "reactome": "R-BTA-177162", "name": "Conjugation of phenylacetate with glutamine", "reactions": [ "reaction_10040185" ] }, "R-BTA-1483248": { "id": "pathway_10094154", "reactome": "R-BTA-1483248", "name": "Synthesis of PIPs at the ER membrane", "reactions": [ "reaction_10060476" ] }, "R-BTA-450604": { "id": "pathway_10093810", "reactome": "R-BTA-450604", "name": "KSRP (KHSRP) binds and destabilizes mRNA", "reactions": [ "reaction_10050380", "reaction_10050408" ] }, "R-BTA-141405": { "id": "pathway_10092892", "reactome": "R-BTA-141405", "name": "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components", "reactions": [ "reaction_10038033", "reaction_10038035" ] }, "R-BTA-168179": { "id": "pathway_10093044", "reactome": "R-BTA-168179", "name": "Toll Like Receptor TLR1:TLR2 Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-174824": { "id": "pathway_10093460", "reactome": "R-BTA-174824", "name": "Plasma lipoprotein assembly, remodeling, and clearance", "reactions": [ "reaction_10074474", "reaction_10044547", "reaction_10074486", "reaction_10084509", "reaction_10086004", "reaction_10086002", "reaction_10084300", "reaction_10086026", "reaction_10083113", "reaction_10086557", "reaction_10085994", "reaction_10077487", "reaction_10077489", "reaction_10088982", "reaction_10044666" ] }, "R-BTA-5693532": { "id": "pathway_10092660", "reactome": "R-BTA-5693532", "name": "DNA Double-Strand Break Repair", "reactions": [ "reaction_10076347", "reaction_10075306", "reaction_10076327", "reaction_10076334", "reaction_10076298", "reaction_10074550", "reaction_10074670", "reaction_10075304", "reaction_10076339", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10074798", "reaction_10074720", "reaction_10035720", "reaction_10075151", "reaction_10075295", "reaction_10074747", "reaction_10075037", "reaction_10035846", "reaction_10076312", "reaction_10076286", "reaction_10074677", "reaction_10076303", "reaction_10075319", "reaction_10074695", "reaction_10075165", "reaction_10035712", "reaction_10076329", "reaction_10075326", "reaction_10076341", "reaction_10076343", "reaction_10074453", "reaction_10074692", "reaction_10076332", "reaction_10075181", "reaction_10074877", "reaction_10074759", "reaction_10074736", "reaction_10068854", "reaction_10074761", "reaction_10074679", "reaction_10075323", "reaction_10075173" ] }, "R-BTA-186712": { "id": "pathway_10093428", "reactome": "R-BTA-186712", "name": "Regulation of beta-cell development", "reactions": [ "reaction_10044090" ] }, "R-BTA-1296072": { "id": "pathway_10094040", "reactome": "R-BTA-1296072", "name": "Voltage gated Potassium channels", "reactions": [ "reaction_10057569" ] }, "R-BTA-68877": { "id": "pathway_10094304", "reactome": "R-BTA-68877", "name": "Mitotic Prometaphase", "reactions": [ "reaction_10065794" ] }, "R-BTA-212436": { "id": "pathway_10092436", "reactome": "R-BTA-212436", "name": "Generic Transcription Pathway", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10072557", "reaction_10086241", "reaction_10088546", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-451326": { "id": "pathway_10093816", "reactome": "R-BTA-451326", "name": "Activation of kainate receptors upon glutamate binding", "reactions": [ "reaction_10050514", "reaction_10051085", "reaction_10050517" ] }, "R-BTA-73942": { "id": "pathway_10094776", "reactome": "R-BTA-73942", "name": "DNA Damage Reversal", "reactions": [ "reaction_10084497" ] }, "R-BTA-9023661": { "id": "pathway_10094910", "reactome": "R-BTA-9023661", "name": "Biosynthesis of E-series 18(R)-resolvins", "reactions": [ "reaction_10090382", "reaction_10090379" ] }, "R-BTA-5693537": { "id": "pathway_10094600", "reactome": "R-BTA-5693537", "name": "Resolution of D-Loop Structures", "reactions": [ "reaction_10075165", "reaction_10075151" ] }, "R-BTA-8937144": { "id": "pathway_10094816", "reactome": "R-BTA-8937144", "name": "Aryl hydrocarbon receptor signalling", "reactions": [ "reaction_10086543" ] }, "R-BTA-6811440": { "id": "pathway_10094712", "reactome": "R-BTA-6811440", "name": "Retrograde transport at the Trans-Golgi-Network", "reactions": [ "reaction_10083340", "reaction_10083342", "reaction_10083143", "reaction_10083179", "reaction_10083187", "reaction_10083149" ] }, "R-BTA-168164": { "id": "pathway_10093062", "reactome": "R-BTA-168164", "name": "Toll Like Receptor 3 (TLR3) Cascade", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-77348": { "id": "pathway_10092714", "reactome": "R-BTA-77348", "name": "Beta oxidation of octanoyl-CoA to hexanoyl-CoA", "reactions": [ "reaction_10036038", "reaction_10036029" ] }, "R-BTA-110320": { "id": "pathway_10092766", "reactome": "R-BTA-110320", "name": "Translesion Synthesis by POLH", "reactions": [ "reaction_10036886", "reaction_10073279", "reaction_10073275", "reaction_10073254", "reaction_10073290", "reaction_10036879", "reaction_10036869" ] }, "R-BTA-190373": { "id": "pathway_10093178", "reactome": "R-BTA-190373", "name": "FGFR1c ligand binding and activation", "reactions": [ "reaction_10040794", "reaction_10040704" ] }, "R-BTA-8854050": { "id": "pathway_10094760", "reactome": "R-BTA-8854050", "name": "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis", "reactions": [ "reaction_10084214", "reaction_10084102", "reaction_10084206", "reaction_10084216" ] }, "R-BTA-6811558": { "id": "pathway_10094146", "reactome": "R-BTA-6811558", "name": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling", "reactions": [ "reaction_10060556", "reaction_10060448" ] }, "R-BTA-73894": { "id": "pathway_10092662", "reactome": "R-BTA-73894", "name": "DNA Repair", "reactions": [ "reaction_10076071", "reaction_10076009", "reaction_10074670", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10073279", "reaction_10091222", "reaction_10036709", "reaction_10074747", "reaction_10036736", "reaction_10076312", "reaction_10076303", "reaction_10075165", "reaction_10071769", "reaction_10076341", "reaction_10075181", "reaction_10074736", "reaction_10036869", "reaction_10036782", "reaction_10036767", "reaction_10071638", "reaction_10077591", "reaction_10075323", "reaction_10076327", "reaction_10091566", "reaction_10036760", "reaction_10075304", "reaction_10073290", "reaction_10074798", "reaction_10071617", "reaction_10074720", "reaction_10071630", "reaction_10036844", "reaction_10088526", "reaction_10091211", "reaction_10073275", "reaction_10075037", "reaction_10091233", "reaction_10071607", "reaction_10084497", "reaction_10036886", "reaction_10075326", "reaction_10071622", "reaction_10076343", "reaction_10076332", "reaction_10074759", "reaction_10036805", "reaction_10036716", "reaction_10074761", "reaction_10075173", "reaction_10076347", "reaction_10071628", "reaction_10071765", "reaction_10076298", "reaction_10074550", "reaction_10036661", "reaction_10076339", "reaction_10036743", "reaction_10035720", "reaction_10075151", "reaction_10036729", "reaction_10071640", "reaction_10072876", "reaction_10076286", "reaction_10075319", "reaction_10077108", "reaction_10036853", "reaction_10036798", "reaction_10074679", "reaction_10077593", "reaction_10075306", "reaction_10077016", "reaction_10071767", "reaction_10077396", "reaction_10073302", "reaction_10036791", "reaction_10075295", "reaction_10073254", "reaction_10035846", "reaction_10074695", "reaction_10074677", "reaction_10035712", "reaction_10076329", "reaction_10077625", "reaction_10074453", "reaction_10074692", "reaction_10074877", "reaction_10091240", "reaction_10072883", "reaction_10068854", "reaction_10076334", "reaction_10036879" ] }, "R-BTA-2162123": { "id": "pathway_10092868", "reactome": "R-BTA-2162123", "name": "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)", "reactions": [ "reaction_10037751", "reaction_10065210", "reaction_10065213", "reaction_10065223", "reaction_10065225", "reaction_10065216", "reaction_10064465", "reaction_10044599", "reaction_10064442", "reaction_10064479", "reaction_10064452", "reaction_10064445", "reaction_10064474", "reaction_10037748" ] }, "R-BTA-2022923": { "id": "pathway_10094196", "reactome": "R-BTA-2022923", "name": "Dermatan sulfate biosynthesis", "reactions": [ "reaction_10062508", "reaction_10062674", "reaction_10062701", "reaction_10062697" ] }, "R-BTA-3928662": { "id": "pathway_10094390", "reactome": "R-BTA-3928662", "name": "EPHB-mediated forward signaling", "reactions": [ "reaction_10069435", "reaction_10069144", "reaction_10069148" ] }, "R-BTA-2168880": { "id": "pathway_10094262", "reactome": "R-BTA-2168880", "name": "Scavenging of heme from plasma", "reactions": [ "reaction_10065163", "reaction_10065173", "reaction_10064753", "reaction_10064757", "reaction_10064765" ] }, "R-BTA-112310": { "id": "pathway_10092504", "reactome": "R-BTA-112310", "name": "Neurotransmitter release cycle", "reactions": [ "reaction_10044076", "reaction_10033755", "reaction_10044540", "reaction_10052018", "reaction_10052013", "reaction_10051999", "reaction_10045419", "reaction_10081481", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10071437", "reaction_10049090", "reaction_10051989", "reaction_10049583" ] }, "R-BTA-196791": { "id": "pathway_10093406", "reactome": "R-BTA-196791", "name": "Vitamin D (calciferol) metabolism", "reactions": [ "reaction_10043984", "reaction_10044741", "reaction_10043903", "reaction_10044739", "reaction_10043910", "reaction_10043885", "reaction_10043964", "reaction_10088928", "reaction_10043971", "reaction_10088926" ] }, "R-BTA-69416": { "id": "pathway_10092614", "reactome": "R-BTA-69416", "name": "Dimerization of procaspase-8", "reactions": [ "reaction_10037991", "reaction_10037985", "reaction_10035396" ] }, "R-BTA-975871": { "id": "pathway_10093032", "reactome": "R-BTA-975871", "name": "MyD88 cascade initiated on plasma membrane", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1855204": { "id": "pathway_10094166", "reactome": "R-BTA-1855204", "name": "Synthesis of IP3 and IP4 in the cytosol", "reactions": [ "reaction_10061084", "reaction_10061076", "reaction_10060917", "reaction_10061113", "reaction_10061006" ] }, "R-BTA-111469": { "id": "pathway_10092832", "reactome": "R-BTA-111469", "name": "SMAC, XIAP-regulated apoptotic response", "reactions": [ "reaction_10091188", "reaction_10037289", "reaction_10091191", "reaction_10037293", "reaction_10091197" ] }, "R-BTA-163685": { "id": "pathway_10092980", "reactome": "R-BTA-163685", "name": "Integration of energy metabolism", "reactions": [ "reaction_10038942", "reaction_10047765", "reaction_10047809", "reaction_10046642", "reaction_10083614", "reaction_10038918", "reaction_10049346", "reaction_10046623", "reaction_10049351", "reaction_10044634", "reaction_10046630", "reaction_10038938", "reaction_10046648" ] }, "R-BTA-69242": { "id": "pathway_10092422", "reactome": "R-BTA-69242", "name": "S Phase", "reactions": [ "reaction_10035745", "reaction_10033504", "reaction_10040521", "reaction_10083565", "reaction_10040183", "reaction_10040542", "reaction_10040576", "reaction_10040503", "reaction_10035747", "reaction_10083558", "reaction_10033473" ] }, "R-BTA-5654704": { "id": "pathway_10094540", "reactome": "R-BTA-5654704", "name": "SHC-mediated cascade:FGFR3", "reactions": [ "reaction_10073140", "reaction_10073152", "reaction_10073159", "reaction_10073156" ] }, "R-BTA-880009": { "id": "pathway_10093874", "reactome": "R-BTA-880009", "name": "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate", "reactions": [ "reaction_10051980", "reaction_10051973" ] }, "R-BTA-418594": { "id": "pathway_10092776", "reactome": "R-BTA-418594", "name": "G alpha (i) signalling events", "reactions": [ "reaction_10037037", "reaction_10089211", "reaction_10039653", "reaction_10037045", "reaction_10039676", "reaction_10088940", "reaction_10039667", "reaction_10039671", "reaction_10039674", "reaction_10036959", "reaction_10039664", "reaction_10039658", "reaction_10089214", "reaction_10089197", "reaction_10037024", "reaction_10036981", "reaction_10037022", "reaction_10037004", "reaction_10048370", "reaction_10049478", "reaction_10039485", "reaction_10046534", "reaction_10039651", "reaction_10088942" ] }, "R-BTA-8866911": { "id": "pathway_10094786", "reactome": "R-BTA-8866911", "name": "TFAP2 (AP-2) family regulates transcription of cell cycle factors", "reactions": [ "reaction_10084935" ] }, "R-BTA-622327": { "id": "pathway_10093848", "reactome": "R-BTA-622327", "name": "Postsynaptic nicotinic acetylcholine receptors", "reactions": [ "reaction_10051523", "reaction_10051521" ] }, "R-BTA-166208": { "id": "pathway_10092998", "reactome": "R-BTA-166208", "name": "mTORC1-mediated signalling", "reactions": [ "reaction_10091741", "reaction_10039160", "reaction_10039200", "reaction_10039209", "reaction_10039155", "reaction_10039180" ] }, "R-BTA-373076": { "id": "pathway_10093502", "reactome": "R-BTA-373076", "name": "Class A/1 (Rhodopsin-like receptors)", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048208", "reaction_10047396", "reaction_10045072", "reaction_10049617", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10053333", "reaction_10046733", "reaction_10047332", "reaction_10078536", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10067358", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-2262752": { "id": "pathway_10092554", "reactome": "R-BTA-2262752", "name": "Cellular responses to stress", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273" ] }, "R-BTA-5250924": { "id": "pathway_10094436", "reactome": "R-BTA-5250924", "name": "B-WICH complex positively regulates rRNA expression", "reactions": [ "reaction_10071065" ] }, "R-BTA-75153": { "id": "pathway_10093342", "reactome": "R-BTA-75153", "name": "Apoptotic execution phase", "reactions": [ "reaction_10044568", "reaction_10044116", "reaction_10043049", "reaction_10044146", "reaction_10043039", "reaction_10044756", "reaction_10044762", "reaction_10044995", "reaction_10044896", "reaction_10044927", "reaction_10044869", "reaction_10044578", "reaction_10044142", "reaction_10043059", "reaction_10044680", "reaction_10043021", "reaction_10090573", "reaction_10044923", "reaction_10090575", "reaction_10044144", "reaction_10044906" ] }, "R-BTA-5654712": { "id": "pathway_10094530", "reactome": "R-BTA-5654712", "name": "FRS-mediated FGFR4 signaling", "reactions": [ "reaction_10073184", "reaction_10073177", "reaction_10073175", "reaction_10073028", "reaction_10073182", "reaction_10087367", "reaction_10073166", "reaction_10073031" ] }, "R-BTA-9018682": { "id": "pathway_10094944", "reactome": "R-BTA-9018682", "name": "Biosynthesis of maresins", "reactions": [ "reaction_10090498" ] }, "R-BTA-190242": { "id": "pathway_10093172", "reactome": "R-BTA-190242", "name": "FGFR1 ligand binding and activation", "reactions": [ "reaction_10040773", "reaction_10040704", "reaction_10040791", "reaction_10040794", "reaction_10040696", "reaction_10040860" ] }, "R-BTA-434313": { "id": "pathway_10093756", "reactome": "R-BTA-434313", "name": "Intracellular metabolism of fatty acids regulates insulin secretion", "reactions": [ "reaction_10049351", "reaction_10049346" ] }, "R-BTA-1250342": { "id": "pathway_10094018", "reactome": "R-BTA-1250342", "name": "PI3K events in ERBB4 signaling", "reactions": [ "reaction_10057184" ] }, "R-BTA-425397": { "id": "pathway_10092728", "reactome": "R-BTA-425397", "name": "Transport of vitamins, nucleosides, and related molecules", "reactions": [ "reaction_10051892", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10036283", "reaction_10051587", "reaction_10051577", "reaction_10039874", "reaction_10036297", "reaction_10071001", "reaction_10051879", "reaction_10051554", "reaction_10038660", "reaction_10070928", "reaction_10051899", "reaction_10091250", "reaction_10051589", "reaction_10071003", "reaction_10051866", "reaction_10036290", "reaction_10073838", "reaction_10049080", "reaction_10051570", "reaction_10036276", "reaction_10051545", "reaction_10051843", "reaction_10051547" ] }, "R-BTA-6787639": { "id": "pathway_10094648", "reactome": "R-BTA-6787639", "name": "GDP-fucose biosynthesis", "reactions": [ "reaction_10077826", "reaction_10077800", "reaction_10077807", "reaction_10077823", "reaction_10077816" ] }, "R-BTA-6811434": { "id": "pathway_10094700", "reactome": "R-BTA-6811434", "name": "COPI-dependent Golgi-to-ER retrograde traffic", "reactions": [ "reaction_10083004", "reaction_10083006", "reaction_10082999" ] }, "R-BTA-9018676": { "id": "pathway_10094918", "reactome": "R-BTA-9018676", "name": "Biosynthesis of D-series resolvins", "reactions": [ "reaction_10090458", "reaction_10090390" ] }, "R-BTA-162710": { "id": "pathway_10092956", "reactome": "R-BTA-162710", "name": "Synthesis of glycosylphosphatidylinositol (GPI)", "reactions": [ "reaction_10038464", "reaction_10038457" ] }, "R-BTA-1793185": { "id": "pathway_10094124", "reactome": "R-BTA-1793185", "name": "Chondroitin sulfate/dermatan sulfate metabolism", "reactions": [ "reaction_10061395", "reaction_10061642", "reaction_10061350", "reaction_10061651", "reaction_10062697", "reaction_10061612", "reaction_10060827", "reaction_10062655", "reaction_10063807", "reaction_10060825", "reaction_10060842", "reaction_10060031", "reaction_10062701", "reaction_10091289", "reaction_10061402", "reaction_10061251", "reaction_10063014", "reaction_10062508", "reaction_10060829", "reaction_10062463", "reaction_10062674", "reaction_10091286" ] }, "R-BTA-69481": { "id": "pathway_10093126", "reactome": "R-BTA-69481", "name": "G2/M Checkpoints", "reactions": [ "reaction_10084051", "reaction_10084047", "reaction_10074692", "reaction_10074695", "reaction_10040059" ] }, "R-BTA-6783984": { "id": "pathway_10094630", "reactome": "R-BTA-6783984", "name": "Glycine degradation", "reactions": [ "reaction_10076441", "reaction_10076459", "reaction_10076450" ] }, "R-BTA-75205": { "id": "pathway_10092916", "reactome": "R-BTA-75205", "name": "Dissolution of Fibrin Clot", "reactions": [ "reaction_10038307", "reaction_10038292", "reaction_10038303", "reaction_10038288", "reaction_10038263", "reaction_10038270", "reaction_10038329", "reaction_10038290", "reaction_10038285" ] }, "R-BTA-5576890": { "id": "pathway_10094456", "reactome": "R-BTA-5576890", "name": "Phase 3 - rapid repolarisation", "reactions": [ "reaction_10071824", "reaction_10071800" ] }, "R-BTA-977068": { "id": "pathway_10093938", "reactome": "R-BTA-977068", "name": "Termination of O-glycan biosynthesis", "reactions": [ "reaction_10054550", "reaction_10054766", "reaction_10054722", "reaction_10054575", "reaction_10054773" ] }, "R-BTA-400042": { "id": "pathway_10093650", "reactome": "R-BTA-400042", "name": "Adrenaline,noradrenaline inhibits insulin secretion", "reactions": [ "reaction_10047765" ] }, "R-BTA-5683057": { "id": "pathway_10094572", "reactome": "R-BTA-5683057", "name": "MAPK family signaling cascades", "reactions": [ "reaction_10075253", "reaction_10091595", "reaction_10091529", "reaction_10091458", "reaction_10074129", "reaction_10075239", "reaction_10074137", "reaction_10091515", "reaction_10091580", "reaction_10074195", "reaction_10075262", "reaction_10091490", "reaction_10076229", "reaction_10073904", "reaction_10091506", "reaction_10075205", "reaction_10073932", "reaction_10074238", "reaction_10076193", "reaction_10091479", "reaction_10091548", "reaction_10074231", "reaction_10091534", "reaction_10074146", "reaction_10091568", "reaction_10075251", "reaction_10075256", "reaction_10074088", "reaction_10075916", "reaction_10075906", "reaction_10075260", "reaction_10073917", "reaction_10091576", "reaction_10074148", "reaction_10073872", "reaction_10073930", "reaction_10074050", "reaction_10073942", "reaction_10091570", "reaction_10074156", "reaction_10074184", "reaction_10076198", "reaction_10073940", "reaction_10075223", "reaction_10074038", "reaction_10091527", "reaction_10073921", "reaction_10075218", "reaction_10091572", "reaction_10074176", "reaction_10074221" ] }, "R-BTA-400451": { "id": "pathway_10093656", "reactome": "R-BTA-400451", "name": "Free fatty acids regulate insulin secretion", "reactions": [ "reaction_10049351", "reaction_10049346", "reaction_10047809" ] }, "R-BTA-9026762": { "id": "pathway_10094936", "reactome": "R-BTA-9026762", "name": "Biosynthesis of maresin conjugates in tissue regeneration (MCTR)", "reactions": [ "reaction_10090480", "reaction_10090489" ] }, "R-BTA-5654228": { "id": "pathway_10094518", "reactome": "R-BTA-5654228", "name": "Phospholipase C-mediated cascade; FGFR4", "reactions": [ "reaction_10072927", "reaction_10072933", "reaction_10072939" ] }, "R-BTA-170834": { "id": "pathway_10094274", "reactome": "R-BTA-170834", "name": "Signaling by TGF-beta Receptor Complex", "reactions": [ "reaction_10064933", "reaction_10071262" ] }, "R-BTA-156582": { "id": "pathway_10092918", "reactome": "R-BTA-156582", "name": "Acetylation", "reactions": [ "reaction_10039918", "reaction_10039921", "reaction_10038316", "reaction_10039923" ] }, "R-BTA-5660526": { "id": "pathway_10094552", "reactome": "R-BTA-5660526", "name": "Response to metal ions", "reactions": [ "reaction_10073446", "reaction_10073481", "reaction_10073460", "reaction_10073468", "reaction_10073464" ] }, "R-BTA-5653656": { "id": "pathway_10093214", "reactome": "R-BTA-5653656", "name": "Vesicle-mediated transport", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10065163", "reaction_10076775", "reaction_10076590", "reaction_10043649", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10064765", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10064753", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10064757", "reaction_10084261", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10086209", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10065173", "reaction_10083342", "reaction_10040961", "reaction_10076778", "reaction_10083767", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-196849": { "id": "pathway_10092518", "reactome": "R-BTA-196849", "name": "Metabolism of water-soluble vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10092306", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10066401", "reaction_10041772", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10041840", "reaction_10041790", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10053350", "reaction_10086748", "reaction_10041753", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10081977", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10086750", "reaction_10086763", "reaction_10053363", "reaction_10081984", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-8852276": { "id": "pathway_10094756", "reactome": "R-BTA-8852276", "name": "The role of GTSE1 in G2/M progression after G2 checkpoint", "reactions": [ "reaction_10084043", "reaction_10084051", "reaction_10084028", "reaction_10084047" ] }, "R-BTA-8876725": { "id": "pathway_10094644", "reactome": "R-BTA-8876725", "name": "Protein methylation", "reactions": [ "reaction_10086286", "reaction_10086303", "reaction_10077744", "reaction_10086319" ] }, "R-BTA-165158": { "id": "pathway_10092736", "reactome": "R-BTA-165158", "name": "Activation of AKT2", "reactions": [ "reaction_10036590", "reaction_10036607", "reaction_10036598" ] }, "R-BTA-9013404": { "id": "pathway_10094892", "reactome": "R-BTA-9013404", "name": "RAC2 GTPase cycle", "reactions": [ "reaction_10090089", "reaction_10092370", "reaction_10092380", "reaction_10090091", "reaction_10090087", "reaction_10090077", "reaction_10092382", "reaction_10090082" ] }, "R-BTA-8964038": { "id": "pathway_10094708", "reactome": "R-BTA-8964038", "name": "LDL clearance", "reactions": [ "reaction_10086004", "reaction_10086002", "reaction_10086026", "reaction_10086557", "reaction_10083113", "reaction_10085994" ] }, "R-BTA-70171": { "id": "pathway_10092472", "reactome": "R-BTA-70171", "name": "Glycolysis", "reactions": [ "reaction_10033611", "reaction_10034071", "reaction_10033629", "reaction_10078710", "reaction_10076815", "reaction_10033620", "reaction_10034157", "reaction_10088737", "reaction_10080765", "reaction_10034140" ] }, "R-BTA-622312": { "id": "pathway_10093866", "reactome": "R-BTA-622312", "name": "Inflammasomes", "reactions": [ "reaction_10051836" ] }, "R-BTA-354192": { "id": "pathway_10093492", "reactome": "R-BTA-354192", "name": "Integrin signaling", "reactions": [ "reaction_10049279", "reaction_10049506", "reaction_10045016", "reaction_10053213" ] }, "R-BTA-162658": { "id": "pathway_10094276", "reactome": "R-BTA-162658", "name": "Golgi Cisternae Pericentriolar Stack Reorganization", "reactions": [ "reaction_10065095" ] }, "R-BTA-194068": { "id": "pathway_10092928", "reactome": "R-BTA-194068", "name": "Bile acid and bile salt metabolism", "reactions": [ "reaction_10041337", "reaction_10085806", "reaction_10041197", "reaction_10041377", "reaction_10041172", "reaction_10041308", "reaction_10041343", "reaction_10041363", "reaction_10041177", "reaction_10041208", "reaction_10085316", "reaction_10041104", "reaction_10041357", "reaction_10085291", "reaction_10041226", "reaction_10041359", "reaction_10041341", "reaction_10041355", "reaction_10041365", "reaction_10041347", "reaction_10041323", "reaction_10041349", "reaction_10038347", "reaction_10041310", "reaction_10041325", "reaction_10041186", "reaction_10041351", "reaction_10041371", "reaction_10041375", "reaction_10041321", "reaction_10041111", "reaction_10041170", "reaction_10041437", "reaction_10041335", "reaction_10041210", "reaction_10041327", "reaction_10041193", "reaction_10041353", "reaction_10041317", "reaction_10041361", "reaction_10041345", "reaction_10041204", "reaction_10041319", "reaction_10041367", "reaction_10041339", "reaction_10041097", "reaction_10041179", "reaction_10041217", "reaction_10041206", "reaction_10041301", "reaction_10041373", "reaction_10041195", "reaction_10041369" ] }, "R-BTA-1474151": { "id": "pathway_10094084", "reactome": "R-BTA-1474151", "name": "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation", "reactions": [ "reaction_10058511", "reaction_10058524", "reaction_10058785", "reaction_10058514" ] }, "R-BTA-1834949": { "id": "pathway_10094190", "reactome": "R-BTA-1834949", "name": "Cytosolic sensors of pathogen-associated DNA ", "reactions": [ "reaction_10063376", "reaction_10066551", "reaction_10066559", "reaction_10066880", "reaction_10067229", "reaction_10066536", "reaction_10067223", "reaction_10067231", "reaction_10067225", "reaction_10065402", "reaction_10065388", "reaction_10065413", "reaction_10067216", "reaction_10090837", "reaction_10061502", "reaction_10066608", "reaction_10065407", "reaction_10090019", "reaction_10067233", "reaction_10066532" ] }, "R-BTA-5358565": { "id": "pathway_10094450", "reactome": "R-BTA-5358565", "name": "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)", "reactions": [ "reaction_10071628", "reaction_10071769", "reaction_10071630", "reaction_10071767", "reaction_10071622", "reaction_10071638", "reaction_10071640", "reaction_10071607" ] }, "R-BTA-432030": { "id": "pathway_10093746", "reactome": "R-BTA-432030", "name": "Transport of glycerol from adipocytes to the liver by Aquaporins", "reactions": [ "reaction_10049271" ] }, "R-BTA-186797": { "id": "pathway_10093554", "reactome": "R-BTA-186797", "name": "Signaling by PDGF", "reactions": [ "reaction_10046666", "reaction_10046660", "reaction_10046677", "reaction_10091689" ] }, "R-BTA-373752": { "id": "pathway_10093524", "reactome": "R-BTA-373752", "name": "Netrin-1 signaling", "reactions": [ "reaction_10045509" ] }, "R-BTA-5654733": { "id": "pathway_10093912", "reactome": "R-BTA-5654733", "name": "Negative regulation of FGFR4 signaling", "reactions": [ "reaction_10073246", "reaction_10057327", "reaction_10057318", "reaction_10073222", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10057302" ] }, "R-BTA-5621481": { "id": "pathway_10094472", "reactome": "R-BTA-5621481", "name": "C-type lectin receptors (CLRs)", "reactions": [ "reaction_10072006", "reaction_10072061", "reaction_10072364", "reaction_10072011", "reaction_10072032", "reaction_10072015", "reaction_10071948", "reaction_10072388", "reaction_10072030", "reaction_10071975", "reaction_10084636", "reaction_10071982", "reaction_10072045", "reaction_10072022", "reaction_10072053", "reaction_10072383", "reaction_10072057", "reaction_10072392", "reaction_10072374", "reaction_10072002", "reaction_10072395" ] }, "R-BTA-8963743": { "id": "pathway_10093164", "reactome": "R-BTA-8963743", "name": "Digestion and absorption", "reactions": [ "reaction_10041239", "reaction_10086435", "reaction_10040866", "reaction_10041241", "reaction_10040868", "reaction_10040870", "reaction_10040872", "reaction_10086248", "reaction_10088973", "reaction_10086350", "reaction_10073378", "reaction_10040608", "reaction_10054375", "reaction_10040617", "reaction_10040620", "reaction_10040629", "reaction_10040595" ] }, "R-BTA-2408522": { "id": "pathway_10094288", "reactome": "R-BTA-2408522", "name": "Selenoamino acid metabolism", "reactions": [ "reaction_10065455" ] }, "R-BTA-2173782": { "id": "pathway_10094264", "reactome": "R-BTA-2173782", "name": "Binding and Uptake of Ligands by Scavenger Receptors", "reactions": [ "reaction_10065163", "reaction_10065173", "reaction_10064753", "reaction_10064757", "reaction_10064765" ] }, "R-BTA-8963896": { "id": "pathway_10094578", "reactome": "R-BTA-8963896", "name": "HDL assembly", "reactions": [ "reaction_10074486", "reaction_10074474" ] }, "R-BTA-71384": { "id": "pathway_10092558", "reactome": "R-BTA-71384", "name": "Ethanol oxidation", "reactions": [ "reaction_10076144", "reaction_10034175", "reaction_10034231", "reaction_10034206", "reaction_10034215", "reaction_10050160" ] }, "R-BTA-8848021": { "id": "pathway_10094724", "reactome": "R-BTA-8848021", "name": "Signaling by PTK6", "reactions": [ "reaction_10083646", "reaction_10083695", "reaction_10083697", "reaction_10083487", "reaction_10083707", "reaction_10083676", "reaction_10083726", "reaction_10083672", "reaction_10083581", "reaction_10083729", "reaction_10083638", "reaction_10083652", "reaction_10083656", "reaction_10084466", "reaction_10083558", "reaction_10083588", "reaction_10083632", "reaction_10083664", "reaction_10083477", "reaction_10083690", "reaction_10083629", "reaction_10083565", "reaction_10083684", "reaction_10083483", "reaction_10083622" ] }, "R-BTA-5205647": { "id": "pathway_10094420", "reactome": "R-BTA-5205647", "name": "Mitophagy", "reactions": [ "reaction_10070261", "reaction_10087615", "reaction_10088891", "reaction_10070265", "reaction_10070259", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-2514853": { "id": "pathway_10094302", "reactome": "R-BTA-2514853", "name": "Condensation of Prometaphase Chromosomes", "reactions": [ "reaction_10065794" ] }, "R-BTA-9615933": { "id": "pathway_10095002", "reactome": "R-BTA-9615933", "name": "Postmitotic nuclear pore complex (NPC) reformation", "reactions": [ "reaction_10091141", "reaction_10091145" ] }, "R-BTA-139910": { "id": "pathway_10092860", "reactome": "R-BTA-139910", "name": "Activation of BMF and translocation to mitochondria", "reactions": [ "reaction_10037702", "reaction_10037706" ] }, "R-BTA-1369007": { "id": "pathway_10093558", "reactome": "R-BTA-1369007", "name": "Mitochondrial ABC transporters", "reactions": [ "reaction_10057832", "reaction_10046698" ] }, "R-BTA-77310": { "id": "pathway_10092704", "reactome": "R-BTA-77310", "name": "Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA", "reactions": [ "reaction_10036021", "reaction_10036012" ] }, "R-BTA-3371556": { "id": "pathway_10094362", "reactome": "R-BTA-3371556", "name": "Cellular response to heat stress", "reactions": [ "reaction_10071208", "reaction_10071127", "reaction_10068008", "reaction_10067993", "reaction_10071313", "reaction_10071241" ] }, "R-BTA-8982491": { "id": "pathway_10092454", "reactome": "R-BTA-8982491", "name": "Glycogen metabolism", "reactions": [ "reaction_10068755", "reaction_10067610", "reaction_10034118", "reaction_10067644", "reaction_10068752", "reaction_10050637", "reaction_10067634", "reaction_10034138", "reaction_10090696", "reaction_10067648", "reaction_10033594", "reaction_10067639", "reaction_10067622", "reaction_10068748" ] }, "R-BTA-9018678": { "id": "pathway_10094240", "reactome": "R-BTA-9018678", "name": "Biosynthesis of specialized proresolving mediators (SPMs)", "reactions": [ "reaction_10090491", "reaction_10064491", "reaction_10090374", "reaction_10090440", "reaction_10090708", "reaction_10090394", "reaction_10090384", "reaction_10090472", "reaction_10090466", "reaction_10064500", "reaction_10090388", "reaction_10090506", "reaction_10090390", "reaction_10090508", "reaction_10090489", "reaction_10090480", "reaction_10090386", "reaction_10090458", "reaction_10090460", "reaction_10090396", "reaction_10090477", "reaction_10090504", "reaction_10090392", "reaction_10090382", "reaction_10090377", "reaction_10090474", "reaction_10090498", "reaction_10090510", "reaction_10090470", "reaction_10090464", "reaction_10090379", "reaction_10090468", "reaction_10090462" ] }, "R-BTA-1489509": { "id": "pathway_10092790", "reactome": "R-BTA-1489509", "name": "DAG and IP3 signaling", "reactions": [ "reaction_10037022", "reaction_10037004", "reaction_10049478", "reaction_10037024", "reaction_10036981", "reaction_10041863" ] }, "R-BTA-375276": { "id": "pathway_10093500", "reactome": "R-BTA-375276", "name": "Peptide ligand-binding receptors", "reactions": [ "reaction_10045324", "reaction_10049645", "reaction_10046917", "reaction_10049683", "reaction_10045406", "reaction_10049637", "reaction_10045384", "reaction_10045196", "reaction_10045180", "reaction_10046733", "reaction_10046731", "reaction_10045072", "reaction_10049570", "reaction_10045292", "reaction_10049639", "reaction_10049699", "reaction_10046919", "reaction_10046953", "reaction_10046729", "reaction_10045268", "reaction_10046735", "reaction_10047483", "reaction_10053335", "reaction_10091037", "reaction_10067358", "reaction_10046915", "reaction_10046763", "reaction_10045362", "reaction_10045350", "reaction_10049520", "reaction_10046773", "reaction_10049661", "reaction_10054775", "reaction_10045168", "reaction_10083880", "reaction_10045332", "reaction_10045156", "reaction_10045094", "reaction_10045106", "reaction_10045280" ] }, "R-BTA-1799339": { "id": "pathway_10094164", "reactome": "R-BTA-1799339", "name": "SRP-dependent cotranslational protein targeting to membrane", "reactions": [ "reaction_10060894" ] }, "R-BTA-428559": { "id": "pathway_10093520", "reactome": "R-BTA-428559", "name": "Proton-coupled neutral amino acid transporters", "reactions": [ "reaction_10045473" ] }, "R-BTA-5654738": { "id": "pathway_10093184", "reactome": "R-BTA-5654738", "name": "Signaling by FGFR2", "reactions": [ "reaction_10073129", "reaction_10072979", "reaction_10057327", "reaction_10072929", "reaction_10040788", "reaction_10072993", "reaction_10040744", "reaction_10073208", "reaction_10040785", "reaction_10073127", "reaction_10072976", "reaction_10057314", "reaction_10057329", "reaction_10073242", "reaction_10059156", "reaction_10053082", "reaction_10073004", "reaction_10073133", "reaction_10057318", "reaction_10072999", "reaction_10072909", "reaction_10073001", "reaction_10087370", "reaction_10040720", "reaction_10072931", "reaction_10073328", "reaction_10073231", "reaction_10073136", "reaction_10057323", "reaction_10057337", "reaction_10057302" ] }, "R-BTA-190322": { "id": "pathway_10093196", "reactome": "R-BTA-190322", "name": "FGFR4 ligand binding and activation", "reactions": [ "reaction_10057704", "reaction_10057707", "reaction_10040776", "reaction_10040769" ] }, "R-BTA-416482": { "id": "pathway_10092836", "reactome": "R-BTA-416482", "name": "G alpha (12/13) signalling events", "reactions": [ "reaction_10037332", "reaction_10047956", "reaction_10047552", "reaction_10048170", "reaction_10051667", "reaction_10037330" ] }, "R-BTA-180336": { "id": "pathway_10093134", "reactome": "R-BTA-180336", "name": "SHC1 events in EGFR signaling", "reactions": [ "reaction_10040286", "reaction_10040331", "reaction_10040303", "reaction_10040258" ] }, "R-BTA-5578768": { "id": "pathway_10094462", "reactome": "R-BTA-5578768", "name": "Physiological factors", "reactions": [ "reaction_10071843", "reaction_10077468" ] }, "R-BTA-947581": { "id": "pathway_10093916", "reactome": "R-BTA-947581", "name": "Molybdenum cofactor biosynthesis", "reactions": [ "reaction_10053298", "reaction_10053287", "reaction_10053266" ] }, "R-BTA-606279": { "id": "pathway_10093836", "reactome": "R-BTA-606279", "name": "Deposition of new CENPA-containing nucleosomes at the centromere", "reactions": [ "reaction_10051465", "reaction_10051461", "reaction_10051451", "reaction_10051463" ] }, "R-BTA-964827": { "id": "pathway_10093918", "reactome": "R-BTA-964827", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2", "reactions": [ "reaction_10053339", "reaction_10053317", "reaction_10053337" ] }, "R-BTA-901042": { "id": "pathway_10093954", "reactome": "R-BTA-901042", "name": "Calnexin/calreticulin cycle", "reactions": [ "reaction_10056058" ] }, "R-BTA-549127": { "id": "pathway_10093830", "reactome": "R-BTA-549127", "name": "Organic cation transport", "reactions": [ "reaction_10051283", "reaction_10051307", "reaction_10051325", "reaction_10051286", "reaction_10051269", "reaction_10051276" ] }, "R-BTA-3299685": { "id": "pathway_10092550", "reactome": "R-BTA-3299685", "name": "Detoxification of Reactive Oxygen Species", "reactions": [ "reaction_10067375", "reaction_10067416", "reaction_10056408", "reaction_10067731", "reaction_10067735", "reaction_10067744", "reaction_10034166", "reaction_10067388", "reaction_10068575", "reaction_10067722", "reaction_10080786", "reaction_10068716", "reaction_10087866", "reaction_10067398", "reaction_10069854", "reaction_10076891", "reaction_10068578" ] }, "R-BTA-187577": { "id": "pathway_10093154", "reactome": "R-BTA-187577", "name": "SCF(Skp2)-mediated degradation of p27/p21", "reactions": [ "reaction_10040542", "reaction_10040521", "reaction_10083565", "reaction_10083558" ] }, "R-BTA-418990": { "id": "pathway_10093686", "reactome": "R-BTA-418990", "name": "Adherens junctions interactions", "reactions": [ "reaction_10048352", "reaction_10048065", "reaction_10048348", "reaction_10048334", "reaction_10048045", "reaction_10049335", "reaction_10048342", "reaction_10048059" ] }, "R-BTA-8866427": { "id": "pathway_10094768", "reactome": "R-BTA-8866427", "name": "VLDLR internalisation and degradation", "reactions": [ "reaction_10084300" ] }, "R-BTA-5654716": { "id": "pathway_10094520", "reactome": "R-BTA-5654716", "name": "Downstream signaling of activated FGFR4", "reactions": [ "reaction_10073237", "reaction_10073047", "reaction_10073184", "reaction_10073044", "reaction_10073177", "reaction_10073175", "reaction_10072939", "reaction_10073028", "reaction_10073037", "reaction_10072927", "reaction_10073192", "reaction_10073240", "reaction_10073182", "reaction_10072933", "reaction_10087367", "reaction_10073166", "reaction_10073041", "reaction_10073031" ] }, "R-BTA-159763": { "id": "pathway_10092940", "reactome": "R-BTA-159763", "name": "Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus", "reactions": [ "reaction_10038438", "reaction_10038408", "reaction_10038416" ] }, "R-BTA-8964208": { "id": "pathway_10092536", "reactome": "R-BTA-8964208", "name": "Phenylalanine metabolism", "reactions": [ "reaction_10033935", "reaction_10052040", "reaction_10064346", "reaction_10076974" ] }, "R-BTA-1433557": { "id": "pathway_10093394", "reactome": "R-BTA-1433557", "name": "Signaling by SCF-KIT", "reactions": [ "reaction_10057845", "reaction_10091751", "reaction_10057854", "reaction_10091667", "reaction_10057867", "reaction_10058474", "reaction_10043815", "reaction_10058480", "reaction_10057862", "reaction_10057850", "reaction_10043832", "reaction_10058478", "reaction_10057857", "reaction_10057872" ] }, "R-BTA-2142688": { "id": "pathway_10094806", "reactome": "R-BTA-2142688", "name": "Synthesis of 5-eicosatetraenoic acids", "reactions": [ "reaction_10086336" ] }, "R-BTA-8949215": { "id": "pathway_10094836", "reactome": "R-BTA-8949215", "name": "Mitochondrial calcium ion transport", "reactions": [ "reaction_10087646" ] }, "R-BTA-70350": { "id": "pathway_10092460", "reactome": "R-BTA-70350", "name": "Fructose catabolism", "reactions": [ "reaction_10083115", "reaction_10033570", "reaction_10033561" ] }, "R-BTA-446388": { "id": "pathway_10093750", "reactome": "R-BTA-446388", "name": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components", "reactions": [ "reaction_10049891", "reaction_10049312", "reaction_10049883" ] }, "R-BTA-937061": { "id": "pathway_10093070", "reactome": "R-BTA-937061", "name": "TRIF(TICAM1)-mediated TLR4 signaling ", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10039560", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10040197", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826" ] }, "R-BTA-189483": { "id": "pathway_10092920", "reactome": "R-BTA-189483", "name": "Heme degradation", "reactions": [ "reaction_10038338", "reaction_10091613", "reaction_10040636", "reaction_10038336", "reaction_10091598", "reaction_10091611", "reaction_10091605" ] }, "R-BTA-190828": { "id": "pathway_10093208", "reactome": "R-BTA-190828", "name": "Gap junction trafficking", "reactions": [ "reaction_10040857", "reaction_10040851", "reaction_10040842", "reaction_10050458", "reaction_10040864" ] }, "R-BTA-450385": { "id": "pathway_10093806", "reactome": "R-BTA-450385", "name": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA", "reactions": [ "reaction_10050373", "reaction_10051066", "reaction_10050318", "reaction_10050366" ] }, "R-BTA-774815": { "id": "pathway_10093838", "reactome": "R-BTA-774815", "name": "Nucleosome assembly", "reactions": [ "reaction_10051465", "reaction_10051461", "reaction_10051451", "reaction_10051463" ] }, "R-BTA-3371378": { "id": "pathway_10094354", "reactome": "R-BTA-3371378", "name": "Regulation by c-FLIP", "reactions": [ "reaction_10068042", "reaction_10067891", "reaction_10067895", "reaction_10068046" ] }, "R-BTA-9018896": { "id": "pathway_10094906", "reactome": "R-BTA-9018896", "name": "Biosynthesis of E-series 18(S)-resolvins", "reactions": [ "reaction_10090396", "reaction_10090440", "reaction_10090374" ] }, "R-BTA-15869": { "id": "pathway_10092548", "reactome": "R-BTA-15869", "name": "Metabolism of nucleotides", "reactions": [ "reaction_10088624", "reaction_10036683", "reaction_10083926", "reaction_10065763", "reaction_10051215", "reaction_10035319", "reaction_10036267", "reaction_10035029", "reaction_10034166", "reaction_10035009", "reaction_10036209", "reaction_10036308", "reaction_10036247", "reaction_10035481", "reaction_10065378", "reaction_10036258", "reaction_10036692", "reaction_10034924", "reaction_10036685", "reaction_10083876", "reaction_10034998", "reaction_10051075", "reaction_10034962", "reaction_10035479", "reaction_10035698", "reaction_10036001", "reaction_10036938", "reaction_10082948", "reaction_10035354", "reaction_10065319", "reaction_10065328", "reaction_10065369", "reaction_10065381", "reaction_10036231", "reaction_10035047", "reaction_10035339", "reaction_10065371", "reaction_10065760", "reaction_10035308", "reaction_10083864", "reaction_10077890", "reaction_10083861", "reaction_10035342", "reaction_10065386", "reaction_10034927", "reaction_10034953", "reaction_10065359", "reaction_10034971", "reaction_10036614", "reaction_10083889", "reaction_10035435", "reaction_10036207", "reaction_10035444", "reaction_10035426", "reaction_10035020", "reaction_10034989", "reaction_10035038", "reaction_10036229", "reaction_10035453", "reaction_10034921", "reaction_10083852", "reaction_10036907", "reaction_10083873", "reaction_10065383", "reaction_10035345", "reaction_10035464", "reaction_10091727", "reaction_10035455", "reaction_10088571", "reaction_10036928", "reaction_10036649", "reaction_10036909", "reaction_10035329", "reaction_10065362", "reaction_10036256", "reaction_10034980", "reaction_10036306", "reaction_10035332", "reaction_10035011", "reaction_10035007", "reaction_10036238" ] }, "R-BTA-198933": { "id": "pathway_10093312", "reactome": "R-BTA-198933", "name": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell", "reactions": [ "reaction_10075009", "reaction_10042253", "reaction_10042129", "reaction_10074993", "reaction_10042623", "reaction_10084658", "reaction_10074899", "reaction_10074901", "reaction_10084672", "reaction_10076963", "reaction_10042786", "reaction_10042635" ] }, "R-BTA-1606341": { "id": "pathway_10094206", "reactome": "R-BTA-1606341", "name": "IRF3 mediated activation of type 1 IFN", "reactions": [ "reaction_10065388", "reaction_10063376" ] }, "R-BTA-111453": { "id": "pathway_10092828", "reactome": "R-BTA-111453", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members", "reactions": [ "reaction_10051181", "reaction_10051175", "reaction_10037277" ] }, "R-BTA-5689603": { "id": "pathway_10094618", "reactome": "R-BTA-5689603", "name": "UCH proteinases", "reactions": [ "reaction_10075942" ] }, "R-BTA-8941855": { "id": "pathway_10094802", "reactome": "R-BTA-8941855", "name": "RUNX3 regulates CDKN1A transcription", "reactions": [ "reaction_10088012", "reaction_10086231" ] }, "R-BTA-112316": { "id": "pathway_10092500", "reactome": "R-BTA-112316", "name": "Neuronal System", "reactions": [ "reaction_10078674", "reaction_10046552", "reaction_10051085", "reaction_10078488", "reaction_10083793", "reaction_10046868", "reaction_10078518", "reaction_10033746", "reaction_10039653", "reaction_10081481", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10049090", "reaction_10057639", "reaction_10051989", "reaction_10057607", "reaction_10049583", "reaction_10033755", "reaction_10052013", "reaction_10052018", "reaction_10078566", "reaction_10050517", "reaction_10057399", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10057616", "reaction_10057350", "reaction_10057682", "reaction_10071437", "reaction_10057365", "reaction_10039664", "reaction_10057656", "reaction_10078466", "reaction_10057588", "reaction_10046151", "reaction_10054318", "reaction_10045455", "reaction_10078446", "reaction_10051999", "reaction_10057665", "reaction_10038000", "reaction_10045419", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10054372", "reaction_10045423", "reaction_10045444", "reaction_10088657", "reaction_10078464", "reaction_10057390", "reaction_10036981", "reaction_10051498", "reaction_10044076", "reaction_10044540", "reaction_10078522", "reaction_10090547", "reaction_10084356", "reaction_10057418", "reaction_10078682", "reaction_10044086", "reaction_10083789", "reaction_10078600", "reaction_10057569", "reaction_10049478", "reaction_10051525", "reaction_10051523", "reaction_10046153", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10045466" ] }, "R-BTA-209968": { "id": "pathway_10093412", "reactome": "R-BTA-209968", "name": "Thyroxine biosynthesis", "reactions": [ "reaction_10043956", "reaction_10043978", "reaction_10043980", "reaction_10044828", "reaction_10076360", "reaction_10043986", "reaction_10043924" ] }, "R-BTA-72689": { "id": "pathway_10092582", "reactome": "R-BTA-72689", "name": "Formation of a pool of free 40S subunits", "reactions": [ "reaction_10034855" ] }, "R-BTA-1296346": { "id": "pathway_10094044", "reactome": "R-BTA-1296346", "name": "Tandem pore domain potassium channels", "reactions": [ "reaction_10057665", "reaction_10057616", "reaction_10057682", "reaction_10057656", "reaction_10057639", "reaction_10057588" ] }, "R-BTA-432047": { "id": "pathway_10093828", "reactome": "R-BTA-432047", "name": "Passive transport by Aquaporins", "reactions": [ "reaction_10051148", "reaction_10051145", "reaction_10051150", "reaction_10051143", "reaction_10051141", "reaction_10051136" ] }, "R-BTA-8941413": { "id": "pathway_10094650", "reactome": "R-BTA-8941413", "name": "Events associated with phagocytolytic activity of PMN cells", "reactions": [ "reaction_10084322", "reaction_10077924", "reaction_10086405", "reaction_10077926", "reaction_10077919" ] }, "R-BTA-913709": { "id": "pathway_10093884", "reactome": "R-BTA-913709", "name": "O-linked glycosylation of mucins", "reactions": [ "reaction_10052546", "reaction_10052690", "reaction_10054550", "reaction_10076773", "reaction_10077688", "reaction_10054766", "reaction_10061538", "reaction_10052521", "reaction_10052665", "reaction_10052606", "reaction_10052496", "reaction_10054722", "reaction_10054575", "reaction_10054773", "reaction_10052716", "reaction_10052461" ] }, "R-BTA-9707564": { "id": "pathway_10092972", "reactome": "R-BTA-9707564", "name": "Cytoprotection by HMOX1", "reactions": [ "reaction_10092310", "reaction_10092308", "reaction_10092289", "reaction_10092312", "reaction_10040636", "reaction_10092273", "reaction_10092293", "reaction_10092287", "reaction_10038647", "reaction_10092239", "reaction_10092214", "reaction_10047807" ] }, "R-BTA-5218859": { "id": "pathway_10092826", "reactome": "R-BTA-5218859", "name": "Regulated Necrosis", "reactions": [ "reaction_10092350", "reaction_10092354", "reaction_10091773", "reaction_10091439", "reaction_10091806", "reaction_10068030", "reaction_10070534", "reaction_10037253", "reaction_10074254", "reaction_10074240", "reaction_10091409", "reaction_10091779", "reaction_10070684", "reaction_10072346", "reaction_10092358", "reaction_10091793", "reaction_10071534", "reaction_10081905", "reaction_10091808", "reaction_10091425", "reaction_10070682", "reaction_10092341", "reaction_10091810", "reaction_10091783", "reaction_10070689", "reaction_10091429", "reaction_10070531", "reaction_10091415", "reaction_10092352", "reaction_10091423", "reaction_10092356" ] }, "R-BTA-9013700": { "id": "pathway_10094974", "reactome": "R-BTA-9013700", "name": "NOTCH4 Activation and Transmission of Signal to the Nucleus", "reactions": [ "reaction_10090834" ] }, "R-BTA-8983711": { "id": "pathway_10094870", "reactome": "R-BTA-8983711", "name": "OAS antiviral response", "reactions": [ "reaction_10089703", "reaction_10089696", "reaction_10089349", "reaction_10089341" ] }, "R-BTA-392518": { "id": "pathway_10093634", "reactome": "R-BTA-392518", "name": "Signal amplification", "reactions": [ "reaction_10049039", "reaction_10047985", "reaction_10049014", "reaction_10047870", "reaction_10091701", "reaction_10047380", "reaction_10047857", "reaction_10047475", "reaction_10049035" ] }, "R-BTA-179812": { "id": "pathway_10092738", "reactome": "R-BTA-179812", "name": "GRB2 events in EGFR signaling", "reactions": [ "reaction_10040317", "reaction_10040326", "reaction_10036616" ] }, "R-BTA-3065679": { "id": "pathway_10094322", "reactome": "R-BTA-3065679", "name": "SUMO is proteolytically processed", "reactions": [ "reaction_10066409", "reaction_10066372", "reaction_10066380" ] }, "R-BTA-73887": { "id": "pathway_10092532", "reactome": "R-BTA-73887", "name": "Death Receptor Signalling", "reactions": [ "reaction_10071556", "reaction_10041333", "reaction_10092026", "reaction_10035726", "reaction_10043778", "reaction_10043739", "reaction_10036148", "reaction_10084723", "reaction_10036146", "reaction_10043744", "reaction_10043753", "reaction_10071534", "reaction_10037964", "reaction_10071526", "reaction_10071524", "reaction_10033926", "reaction_10092031", "reaction_10071541", "reaction_10041470", "reaction_10043877", "reaction_10067908", "reaction_10067895" ] }, "R-BTA-71403": { "id": "pathway_10092514", "reactome": "R-BTA-71403", "name": "Citric acid cycle (TCA cycle)", "reactions": [ "reaction_10089782", "reaction_10050446", "reaction_10050437", "reaction_10089795", "reaction_10089808", "reaction_10033868" ] }, "R-BTA-427975": { "id": "pathway_10093724", "reactome": "R-BTA-427975", "name": "Proton/oligopeptide cotransporters", "reactions": [ "reaction_10048802", "reaction_10048795" ] }, "R-BTA-1855167": { "id": "pathway_10094174", "reactome": "R-BTA-1855167", "name": "Synthesis of pyrophosphates in the cytosol", "reactions": [ "reaction_10061116", "reaction_10060956", "reaction_10061037", "reaction_10060980", "reaction_10063018", "reaction_10061125", "reaction_10061011", "reaction_10061079", "reaction_10061040", "reaction_10063020", "reaction_10061034", "reaction_10061024", "reaction_10060983" ] }, "R-BTA-73929": { "id": "pathway_10092752", "reactome": "R-BTA-73929", "name": "Base-Excision Repair, AP Site Formation", "reactions": [ "reaction_10036716", "reaction_10091566", "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036767", "reaction_10036709", "reaction_10091211", "reaction_10036729", "reaction_10036798", "reaction_10036736", "reaction_10091233", "reaction_10091240", "reaction_10036743", "reaction_10036805" ] }, "R-BTA-6804115": { "id": "pathway_10094664", "reactome": "R-BTA-6804115", "name": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "reactions": [ "reaction_10081380", "reaction_10078658" ] }, "R-BTA-69002": { "id": "pathway_10092400", "reactome": "R-BTA-69002", "name": "DNA Replication Pre-Initiation", "reactions": [ "reaction_10033379", "reaction_10033412", "reaction_10033512", "reaction_10033466" ] }, "R-BTA-190377": { "id": "pathway_10093186", "reactome": "R-BTA-190377", "name": "FGFR2b ligand binding and activation", "reactions": [ "reaction_10073328", "reaction_10040744", "reaction_10040785" ] }, "R-BTA-73854": { "id": "pathway_10092600", "reactome": "R-BTA-73854", "name": "RNA Polymerase I Promoter Clearance", "reactions": [ "reaction_10035301", "reaction_10035254" ] }, "R-BTA-9024446": { "id": "pathway_10094924", "reactome": "R-BTA-9024446", "name": "NR1H2 and NR1H3-mediated signaling", "reactions": [ "reaction_10090456", "reaction_10090563", "reaction_10090567", "reaction_10090571", "reaction_10090452", "reaction_10090559", "reaction_10090555" ] }, "R-BTA-3322077": { "id": "pathway_10092452", "reactome": "R-BTA-3322077", "name": "Glycogen synthesis", "reactions": [ "reaction_10068755", "reaction_10067610", "reaction_10067644", "reaction_10068752", "reaction_10067634", "reaction_10067648", "reaction_10067639", "reaction_10067622", "reaction_10068748" ] }, "R-BTA-110331": { "id": "pathway_10092756", "reactome": "R-BTA-110331", "name": "Cleavage of the damaged purine", "reactions": [ "reaction_10091222", "reaction_10036782", "reaction_10036760", "reaction_10036791", "reaction_10036798", "reaction_10091233", "reaction_10091240", "reaction_10036805" ] }, "R-BTA-8943724": { "id": "pathway_10094828", "reactome": "R-BTA-8943724", "name": "Regulation of PTEN gene transcription", "reactions": [ "reaction_10087531" ] }, "R-BTA-166663": { "id": "pathway_10093020", "reactome": "R-BTA-166663", "name": "Initial triggering of complement", "reactions": [ "reaction_10039782", "reaction_10039465", "reaction_10054736", "reaction_10039778" ] }, "R-BTA-373760": { "id": "pathway_10093508", "reactome": "R-BTA-373760", "name": "L1CAM interactions", "reactions": [ "reaction_10045224" ] }, "R-BTA-167827": { "id": "pathway_10093084", "reactome": "R-BTA-167827", "name": "The proton buffering model", "reactions": [ "reaction_10039604" ] }, "R-BTA-8951664": { "id": "pathway_10094616", "reactome": "R-BTA-8951664", "name": "Neddylation", "reactions": [ "reaction_10088688", "reaction_10087883", "reaction_10088734", "reaction_10087852", "reaction_10088787", "reaction_10087848", "reaction_10075942", "reaction_10087825", "reaction_10087885", "reaction_10088807", "reaction_10087993" ] }, "R-BTA-9615017": { "id": "pathway_10094986", "reactome": "R-BTA-9615017", "name": "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes", "reactions": [ "reaction_10091049" ] }, "R-BTA-9026766": { "id": "pathway_10094940", "reactome": "R-BTA-9026766", "name": "Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)", "reactions": [ "reaction_10090491" ] }, "R-BTA-8964572": { "id": "pathway_10094770", "reactome": "R-BTA-8964572", "name": "Lipid particle organization", "reactions": [ "reaction_10084424", "reaction_10084694", "reaction_10084480" ] }, "R-BTA-964975": { "id": "pathway_10093922", "reactome": "R-BTA-964975", "name": "Vitamins B6 activation to pyridoxal phosphate", "reactions": [ "reaction_10053361", "reaction_10053352", "reaction_10053350", "reaction_10053363", "reaction_10053348", "reaction_10066619" ] }, "R-BTA-450520": { "id": "pathway_10093802", "reactome": "R-BTA-450520", "name": "HuR (ELAVL1) binds and stabilizes mRNA", "reactions": [ "reaction_10050306", "reaction_10051219", "reaction_10050378", "reaction_10051221", "reaction_10050368", "reaction_10050400" ] }, "R-BTA-420597": { "id": "pathway_10093696", "reactome": "R-BTA-420597", "name": "Nectin/Necl trans heterodimerization", "reactions": [ "reaction_10048334", "reaction_10048342", "reaction_10048352" ] }, "R-BTA-9026286": { "id": "pathway_10094930", "reactome": "R-BTA-9026286", "name": "Biosynthesis of DPAn-3-derived protectins and resolvins", "reactions": [ "reaction_10090470" ] }, "R-BTA-2179392": { "id": "pathway_10094268", "reactome": "R-BTA-2179392", "name": "EGFR Transactivation by Gastrin", "reactions": [ "reaction_10064919", "reaction_10064915", "reaction_10064910" ] }, "R-BTA-166058": { "id": "pathway_10093038", "reactome": "R-BTA-166058", "name": "MyD88:MAL(TIRAP) cascade initiated on plasma membrane", "reactions": [ "reaction_10050208", "reaction_10050254", "reaction_10065894", "reaction_10050192", "reaction_10050218", "reaction_10050196", "reaction_10041950", "reaction_10043488", "reaction_10039508", "reaction_10050231", "reaction_10050256", "reaction_10042826", "reaction_10039481" ] }, "R-BTA-1630316": { "id": "pathway_10093122", "reactome": "R-BTA-1630316", "name": "Glycosaminoglycan metabolism", "reactions": [ "reaction_10061395", "reaction_10062984", "reaction_10064595", "reaction_10063520", "reaction_10061642", "reaction_10039887", "reaction_10063249", "reaction_10063510", "reaction_10061350", "reaction_10063610", "reaction_10060293", "reaction_10061651", "reaction_10060685", "reaction_10062697", "reaction_10060741", "reaction_10063801", "reaction_10060827", "reaction_10061612", "reaction_10091291", "reaction_10060295", "reaction_10063010", "reaction_10063803", "reaction_10060671", "reaction_10062655", "reaction_10063216", "reaction_10064355", "reaction_10039890", "reaction_10064593", "reaction_10091293", "reaction_10048727", "reaction_10064393", "reaction_10060678", "reaction_10063807", "reaction_10063477", "reaction_10051589", "reaction_10060825", "reaction_10060634", "reaction_10060842", "reaction_10060625", "reaction_10060031", "reaction_10063485", "reaction_10062701", "reaction_10063232", "reaction_10091289", "reaction_10063805", "reaction_10061402", "reaction_10063508", "reaction_10060285", "reaction_10063014", "reaction_10061251", "reaction_10063633", "reaction_10064353", "reaction_10062508", "reaction_10063530", "reaction_10064597", "reaction_10051570", "reaction_10060829", "reaction_10062463", "reaction_10063022", "reaction_10063603", "reaction_10063586", "reaction_10062674", "reaction_10063532", "reaction_10091286", "reaction_10064391" ] }, "R-BTA-2995410": { "id": "pathway_10095000", "reactome": "R-BTA-2995410", "name": "Nuclear Envelope (NE) Reassembly", "reactions": [ "reaction_10091634", "reaction_10091145", "reaction_10091656", "reaction_10091661", "reaction_10091141", "reaction_10091658", "reaction_10091132" ] }, "R-BTA-6804758": { "id": "pathway_10094336", "reactome": "R-BTA-6804758", "name": "Regulation of TP53 Activity through Acetylation", "reactions": [ "reaction_10082931", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10083077", "reaction_10083072", "reaction_10082923", "reaction_10082934", "reaction_10072550" ] }, "R-BTA-379716": { "id": "pathway_10092566", "reactome": "R-BTA-379716", "name": "Cytosolic tRNA aminoacylation", "reactions": [ "reaction_10034224" ] }, "R-BTA-2022854": { "id": "pathway_10093850", "reactome": "R-BTA-2022854", "name": "Keratan sulfate biosynthesis", "reactions": [ "reaction_10063530", "reaction_10063485", "reaction_10063520", "reaction_10063232", "reaction_10063249", "reaction_10063508", "reaction_10063532", "reaction_10063477", "reaction_10051589" ] }, "R-BTA-5654700": { "id": "pathway_10094524", "reactome": "R-BTA-5654700", "name": "FRS-mediated FGFR2 signaling", "reactions": [ "reaction_10073133", "reaction_10073127", "reaction_10087370", "reaction_10073129", "reaction_10072979", "reaction_10072976", "reaction_10073136" ] }, "R-BTA-1638091": { "id": "pathway_10093856", "reactome": "R-BTA-1638091", "name": "Heparan sulfate/heparin (HS-GAG) metabolism", "reactions": [ "reaction_10062984", "reaction_10061395", "reaction_10063610", "reaction_10060685", "reaction_10061350", "reaction_10060741", "reaction_10063801", "reaction_10063010", "reaction_10063803", "reaction_10060671", "reaction_10063216", "reaction_10060678", "reaction_10060634", "reaction_10051589", "reaction_10060625", "reaction_10063805", "reaction_10061402", "reaction_10063633", "reaction_10061251", "reaction_10063022", "reaction_10063603", "reaction_10063586", "reaction_10091286" ] }, "R-BTA-6796648": { "id": "pathway_10094662", "reactome": "R-BTA-6796648", "name": "TP53 Regulates Transcription of DNA Repair Genes", "reactions": [ "reaction_10078474" ] }, "R-BTA-9716542": { "id": "pathway_10093370", "reactome": "R-BTA-9716542", "name": "Signaling by Rho GTPases, Miro GTPases and RHOBTB3", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10092205", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10092203", "reaction_10072515", "reaction_10073503", "reaction_10092208", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] }, "R-BTA-1660516": { "id": "pathway_10094158", "reactome": "R-BTA-1660516", "name": "Synthesis of PIPs at the early endosome membrane", "reactions": [ "reaction_10060574", "reaction_10060558", "reaction_10060588", "reaction_10060518", "reaction_10060614", "reaction_10060501", "reaction_10083800" ] }, "R-BTA-446652": { "id": "pathway_10093400", "reactome": "R-BTA-446652", "name": "Interleukin-1 family signaling", "reactions": [ "reaction_10050028", "reaction_10083537", "reaction_10089591", "reaction_10089843", "reaction_10089615", "reaction_10089625", "reaction_10050428", "reaction_10083522", "reaction_10050420", "reaction_10091757", "reaction_10089597", "reaction_10050011", "reaction_10051095", "reaction_10043867", "reaction_10089812", "reaction_10089595", "reaction_10089819", "reaction_10089621", "reaction_10049721", "reaction_10050024", "reaction_10087338" ] }, "R-BTA-1592230": { "id": "pathway_10094610", "reactome": "R-BTA-1592230", "name": "Mitochondrial biogenesis", "reactions": [ "reaction_10087635", "reaction_10075362", "reaction_10075350" ] }, "R-BTA-977443": { "id": "pathway_10093098", "reactome": "R-BTA-977443", "name": "GABA receptor activation", "reactions": [ "reaction_10039653", "reaction_10054361", "reaction_10039676", "reaction_10054372", "reaction_10039651", "reaction_10039664" ] }, "R-BTA-525793": { "id": "pathway_10093794", "reactome": "R-BTA-525793", "name": "Myogenesis", "reactions": [ "reaction_10050085", "reaction_10050116" ] }, "R-BTA-1632852": { "id": "pathway_10094424", "reactome": "R-BTA-1632852", "name": "Macroautophagy", "reactions": [ "reaction_10070261", "reaction_10073831", "reaction_10074142", "reaction_10074302", "reaction_10090398", "reaction_10087615", "reaction_10074415", "reaction_10073835", "reaction_10074381", "reaction_10074365", "reaction_10074507", "reaction_10074659", "reaction_10070265", "reaction_10070259", "reaction_10088891", "reaction_10087621", "reaction_10070218" ] }, "R-BTA-76005": { "id": "pathway_10093738", "reactome": "R-BTA-76005", "name": "Response to elevated platelet cytosolic Ca2+", "reactions": [ "reaction_10050994", "reaction_10051062", "reaction_10050948", "reaction_10050870", "reaction_10051002", "reaction_10050924", "reaction_10049067" ] }, "R-BTA-916853": { "id": "pathway_10093876", "reactome": "R-BTA-916853", "name": "Degradation of GABA", "reactions": [ "reaction_10051989" ] }, "R-BTA-163841": { "id": "pathway_10092944", "reactome": "R-BTA-163841", "name": "Gamma carboxylation, hypusine formation and arylsulfatase activation", "reactions": [ "reaction_10091630", "reaction_10071566", "reaction_10038408", "reaction_10060109", "reaction_10038416", "reaction_10077883", "reaction_10071579", "reaction_10043717", "reaction_10038438", "reaction_10043698", "reaction_10077897" ] }, "R-BTA-5654732": { "id": "pathway_10093906", "reactome": "R-BTA-5654732", "name": "Negative regulation of FGFR3 signaling", "reactions": [ "reaction_10057327", "reaction_10057318", "reaction_10073244", "reaction_10057314", "reaction_10057329", "reaction_10057323", "reaction_10059156", "reaction_10057337", "reaction_10053082", "reaction_10073215", "reaction_10057302" ] }, "R-BTA-190374": { "id": "pathway_10093200", "reactome": "R-BTA-190374", "name": "FGFR1c and Klotho ligand binding and activation", "reactions": [ "reaction_10040860", "reaction_10040773" ] }, "R-BTA-5423646": { "id": "pathway_10092904", "reactome": "R-BTA-5423646", "name": "Aflatoxin activation and detoxification", "reactions": [ "reaction_10071722", "reaction_10071712", "reaction_10071715", "reaction_10071729", "reaction_10071727", "reaction_10038060", "reaction_10071717", "reaction_10071763", "reaction_10071754" ] }, "R-BTA-1236977": { "id": "pathway_10093996", "reactome": "R-BTA-1236977", "name": "Endosomal/Vacuolar pathway", "reactions": [ "reaction_10056914", "reaction_10056903", "reaction_10056910" ] }, "R-BTA-194002": { "id": "pathway_10093252", "reactome": "R-BTA-194002", "name": "Glucocorticoid biosynthesis", "reactions": [ "reaction_10041412", "reaction_10041395", "reaction_10041721", "reaction_10057880", "reaction_10041424", "reaction_10041379", "reaction_10041284" ] }, "R-BTA-71737": { "id": "pathway_10092564", "reactome": "R-BTA-71737", "name": "Pyrophosphate hydrolysis", "reactions": [ "reaction_10050169", "reaction_10034224" ] }, "R-BTA-1482925": { "id": "pathway_10094094", "reactome": "R-BTA-1482925", "name": "Acyl chain remodelling of PG", "reactions": [ "reaction_10059847", "reaction_10058877", "reaction_10058934", "reaction_10059018", "reaction_10058812", "reaction_10059021", "reaction_10058826", "reaction_10059016", "reaction_10058983", "reaction_10058913" ] } }, "super_pathways": { "R-BTA-446203": { "id": "pathway_10093226", "reactome": "R-BTA-446203", "name": "Asparagine N-linked glycosylation", "reactions": [ "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10077710", "reaction_10053317", "reaction_10076708", "reaction_10076610", "reaction_10069371", "reaction_10077823", "reaction_10056058", "reaction_10054467", "reaction_10082941", "reaction_10069320", "reaction_10049797", "reaction_10069359", "reaction_10054474", "reaction_10049860", "reaction_10076584", "reaction_10053324", "reaction_10069357", "reaction_10049789", "reaction_10081490", "reaction_10049818", "reaction_10054418", "reaction_10049811", "reaction_10077800", "reaction_10069346", "reaction_10051554", "reaction_10049804", "reaction_10049867", "reaction_10076696", "reaction_10076635", "reaction_10069368", "reaction_10054438", "reaction_10076586", "reaction_10076736", "reaction_10076706", "reaction_10040933", "reaction_10053337", "reaction_10084373", "reaction_10056061", "reaction_10069373", "reaction_10049858", "reaction_10077807", "reaction_10069329", "reaction_10069498", "reaction_10056074", "reaction_10077717", "reaction_10082026", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10053339", "reaction_10076422", "reaction_10054411", "reaction_10077826", "reaction_10076415", "reaction_10049831", "reaction_10083380", "reaction_10049851", "reaction_10049778", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10049844", "reaction_10076778", "reaction_10050153", "reaction_10053331", "reaction_10048958", "reaction_10077816", "reaction_10076698", "reaction_10069382" ] }, "R-BTA-8978868": { "id": "pathway_10092526", "reactome": "R-BTA-8978868", "name": "Fatty acid metabolism", "reactions": [ "reaction_10064516", "reaction_10082880", "reaction_10051252", "reaction_10036220", "reaction_10065216", "reaction_10046992", "reaction_10064565", "reaction_10042860", "reaction_10086336", "reaction_10036038", "reaction_10063430", "reaction_10063442", "reaction_10064506", "reaction_10036029", "reaction_10036040", "reaction_10063444", "reaction_10044657", "reaction_10063425", "reaction_10063428", "reaction_10036218", "reaction_10064442", "reaction_10063570", "reaction_10065225", "reaction_10046984", "reaction_10042961", "reaction_10064521", "reaction_10047001", "reaction_10085185", "reaction_10047058", "reaction_10036021", "reaction_10033912", "reaction_10064465", "reaction_10033896", "reaction_10075607", "reaction_10065213", "reaction_10064567", "reaction_10064482", "reaction_10077784", "reaction_10063420", "reaction_10064452", "reaction_10086403", "reaction_10047042", "reaction_10064479", "reaction_10063440", "reaction_10064546", "reaction_10074353", "reaction_10077835", "reaction_10037751", "reaction_10065210", "reaction_10047044", "reaction_10064554", "reaction_10065223", "reaction_10083389", "reaction_10036025", "reaction_10044599", "reaction_10064474", "reaction_10054592", "reaction_10037748", "reaction_10064578", "reaction_10036042", "reaction_10046989", "reaction_10036664", "reaction_10063452", "reaction_10076382", "reaction_10063413", "reaction_10036027", "reaction_10063446", "reaction_10047056", "reaction_10063437", "reaction_10036012", "reaction_10064445", "reaction_10047033", "reaction_10033889", "reaction_10042897", "reaction_10047053", "reaction_10076806", "reaction_10036023", "reaction_10064581", "reaction_10064503", "reaction_10063573", "reaction_10064534", "reaction_10063450", "reaction_10077001", "reaction_10064531", "reaction_10064526", "reaction_10075576", "reaction_10064511", "reaction_10044151", "reaction_10051261", "reaction_10075631", "reaction_10082889", "reaction_10063454", "reaction_10063456", "reaction_10063448" ] }, "R-BTA-449147": { "id": "pathway_10093066", "reactome": "R-BTA-449147", "name": "Signaling by Interleukins", "reactions": [ "reaction_10051194", "reaction_10056201", "reaction_10051936", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10052254", "reaction_10089466", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10089691", "reaction_10050231", "reaction_10042826", "reaction_10051966", "reaction_10050011", "reaction_10089329", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10049970", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10056110", "reaction_10089431", "reaction_10089540", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10090031", "reaction_10089536", "reaction_10089251", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10090027", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10050256", "reaction_10056194", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10089689", "reaction_10043867", "reaction_10077723", "reaction_10056132", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10077424", "reaction_10056207", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10089542", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10087766", "reaction_10049928", "reaction_10050428", "reaction_10083522", "reaction_10039508", "reaction_10050420", "reaction_10087650", "reaction_10052327", "reaction_10089736", "reaction_10051949", "reaction_10089269", "reaction_10089597", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10056168", "reaction_10087793", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10085017", "reaction_10051954", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-162582": { "id": "pathway_10092534", "reactome": "R-BTA-162582", "name": "Signal Transduction", "reactions": [ "reaction_10047236", "reaction_10073796", "reaction_10040769", "reaction_10090087", "reaction_10073716", "reaction_10041917", "reaction_10047362", "reaction_10047979", "reaction_10041463", "reaction_10047398", "reaction_10091158", "reaction_10063374", "reaction_10047334", "reaction_10091156", "reaction_10063319", "reaction_10073021", "reaction_10090198", "reaction_10086575", "reaction_10067364", "reaction_10057318", "reaction_10068933", "reaction_10056781", "reaction_10068939", "reaction_10047851", "reaction_10091576", "reaction_10063534", "reaction_10068086", "reaction_10063843", "reaction_10083588", "reaction_10069651", "reaction_10083632", "reaction_10090675", "reaction_10037549", "reaction_10072123", "reaction_10037022", "reaction_10083878", "reaction_10083629", "reaction_10091118", "reaction_10060448", "reaction_10083880", "reaction_10075223", "reaction_10043488", "reaction_10091267", "reaction_10040761", "reaction_10061492", "reaction_10057236", "reaction_10090330", "reaction_10072946", "reaction_10083646", "reaction_10040489", "reaction_10072715", "reaction_10083695", "reaction_10088940", "reaction_10074137", "reaction_10040258", "reaction_10047210", "reaction_10047256", "reaction_10041869", "reaction_10046572", "reaction_10091751", "reaction_10049699", "reaction_10071508", "reaction_10091556", "reaction_10046919", "reaction_10073122", "reaction_10040326", "reaction_10076193", "reaction_10040696", "reaction_10046953", "reaction_10047374", "reaction_10058474", "reaction_10073044", "reaction_10089947", "reaction_10091271", "reaction_10071534", "reaction_10068839", "reaction_10089011", "reaction_10044465", "reaction_10046915", "reaction_10074879", "reaction_10067204", "reaction_10040773", "reaction_10084080", "reaction_10074184", "reaction_10064910", "reaction_10040458", "reaction_10045168", "reaction_10072685", "reaction_10046534", "reaction_10047857", "reaction_10045332", "reaction_10090555", "reaction_10040782", "reaction_10073041", "reaction_10063317", "reaction_10048214", "reaction_10072720", "reaction_10091458", "reaction_10035527", "reaction_10040317", "reaction_10047226", "reaction_10072929", "reaction_10071397", "reaction_10084016", "reaction_10071407", "reaction_10064933", "reaction_10046660", "reaction_10067698", "reaction_10072397", "reaction_10089222", "reaction_10072976", "reaction_10071506", "reaction_10046677", "reaction_10039674", "reaction_10091115", "reaction_10072900", "reaction_10036146", "reaction_10046729", "reaction_10077601", "reaction_10041583", "reaction_10072677", "reaction_10091896", "reaction_10057744", "reaction_10040794", "reaction_10068837", "reaction_10046763", "reaction_10083664", "reaction_10063568", "reaction_10071678", "reaction_10073246", "reaction_10090964", "reaction_10073177", "reaction_10075097", "reaction_10063550", "reaction_10063556", "reaction_10048632", "reaction_10089952", "reaction_10057323", "reaction_10039160", "reaction_10074176", "reaction_10069459", "reaction_10049645", "reaction_10073549", "reaction_10047866", "reaction_10068073", "reaction_10039653", "reaction_10073090", "reaction_10047468", "reaction_10090501", "reaction_10069645", "reaction_10053333", "reaction_10063554", "reaction_10057850", "reaction_10090009", "reaction_10075262", "reaction_10091916", "reaction_10090666", "reaction_10036570", "reaction_10089203", "reaction_10069535", "reaction_10092203", "reaction_10072515", "reaction_10049657", "reaction_10073503", "reaction_10066994", "reaction_10048180", "reaction_10087367", "reaction_10040684", "reaction_10046735", "reaction_10072606", "reaction_10073755", "reaction_10074088", "reaction_10041604", "reaction_10091689", "reaction_10075260", "reaction_10088493", "reaction_10072628", "reaction_10071648", "reaction_10073930", "reaction_10092364", "reaction_10090203", "reaction_10074156", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10091864", "reaction_10073182", "reaction_10073921", "reaction_10039651", "reaction_10073559", "reaction_10040860", "reaction_10036616", "reaction_10057302", "reaction_10040286", "reaction_10040393", "reaction_10071504", "reaction_10045384", "reaction_10037045", "reaction_10091812", "reaction_10057139", "reaction_10073904", "reaction_10039736", "reaction_10071356", "reaction_10073234", "reaction_10092205", "reaction_10044470", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10074231", "reaction_10045268", "reaction_10090949", "reaction_10067350", "reaction_10083638", "reaction_10063353", "reaction_10073525", "reaction_10069593", "reaction_10069299", "reaction_10073102", "reaction_10045350", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10073569", "reaction_10044211", "reaction_10067200", "reaction_10039485", "reaction_10072937", "reaction_10074038", "reaction_10091527", "reaction_10073201", "reaction_10047354", "reaction_10045324", "reaction_10040331", "reaction_10088942", "reaction_10039272", "reaction_10067124", "reaction_10091180", "reaction_10090306", "reaction_10072939", "reaction_10040289", "reaction_10056354", "reaction_10073106", "reaction_10083697", "reaction_10073113", "reaction_10048208", "reaction_10045072", "reaction_10039601", "reaction_10043778", "reaction_10091506", "reaction_10035536", "reaction_10064919", "reaction_10073932", "reaction_10047364", "reaction_10069607", "reaction_10049279", "reaction_10057262", "reaction_10090956", "reaction_10072433", "reaction_10039127", "reaction_10073133", "reaction_10057700", "reaction_10083656", "reaction_10073228", "reaction_10092382", "reaction_10057704", "reaction_10047212", "reaction_10049506", "reaction_10041950", "reaction_10040369", "reaction_10057857", "reaction_10041453", "reaction_10071673", "reaction_10091151", "reaction_10069882", "reaction_10049683", "reaction_10089860", "reaction_10073222", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10090452", "reaction_10042976", "reaction_10051656", "reaction_10049894", "reaction_10090103", "reaction_10046588", "reaction_10091921", "reaction_10067694", "reaction_10070628", "reaction_10045292", "reaction_10091902", "reaction_10092002", "reaction_10073853", "reaction_10047366", "reaction_10091832", "reaction_10046666", "reaction_10073004", "reaction_10057177", "reaction_10090311", "reaction_10043744", "reaction_10077605", "reaction_10083652", "reaction_10076840", "reaction_10063544", "reaction_10083933", "reaction_10036607", "reaction_10047234", "reaction_10073731", "reaction_10037004", "reaction_10049520", "reaction_10039592", "reaction_10057719", "reaction_10073940", "reaction_10049478", "reaction_10051667", "reaction_10065099", "reaction_10048660", "reaction_10040310", "reaction_10041863", "reaction_10073851", "reaction_10039180", "reaction_10071556", "reaction_10090563", "reaction_10073129", "reaction_10090145", "reaction_10046917", "reaction_10043315", "reaction_10073083", "reaction_10040299", "reaction_10067879", "reaction_10040785", "reaction_10091275", "reaction_10040570", "reaction_10063382", "reaction_10048178", "reaction_10057284", "reaction_10071320", "reaction_10084723", "reaction_10090559", "reaction_10083935", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10047483", "reaction_10075916", "reaction_10047956", "reaction_10040704", "reaction_10057742", "reaction_10089214", "reaction_10067358", "reaction_10090369", "reaction_10036981", "reaction_10041647", "reaction_10074050", "reaction_10073942", "reaction_10089890", "reaction_10091570", "reaction_10070657", "reaction_10048282", "reaction_10090266", "reaction_10067696", "reaction_10057272", "reaction_10041606", "reaction_10040791", "reaction_10047222", "reaction_10092020", "reaction_10091247", "reaction_10045106", "reaction_10087531", "reaction_10074195", "reaction_10067128", "reaction_10037037", "reaction_10090994", "reaction_10073147", "reaction_10057327", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10090119", "reaction_10067360", "reaction_10039676", "reaction_10075239", "reaction_10041637", "reaction_10040229", "reaction_10040744", "reaction_10045180", "reaction_10040779", "reaction_10090082", "reaction_10090339", "reaction_10091741", "reaction_10048326", "reaction_10089224", "reaction_10049570", "reaction_10057862", "reaction_10048587", "reaction_10072902", "reaction_10039581", "reaction_10046149", "reaction_10084849", "reaction_10070676", "reaction_10091884", "reaction_10039697", "reaction_10063338", "reaction_10053335", "reaction_10049585", "reaction_10073115", "reaction_10072999", "reaction_10039059", "reaction_10086415", "reaction_10090246", "reaction_10073001", "reaction_10040447", "reaction_10063346", "reaction_10071668", "reaction_10089841", "reaction_10040421", "reaction_10083565", "reaction_10048370", "reaction_10089149", "reaction_10047214", "reaction_10091572", "reaction_10057184", "reaction_10045280", "reaction_10074221", "reaction_10091169", "reaction_10075253", "reaction_10073326", "reaction_10057191", "reaction_10056356", "reaction_10073507", "reaction_10057286", "reaction_10092026", "reaction_10073208", "reaction_10048248", "reaction_10090089", "reaction_10047396", "reaction_10047498", "reaction_10049617", "reaction_10035726", "reaction_10089972", "reaction_10061449", "reaction_10040432", "reaction_10069876", "reaction_10047853", "reaction_10074238", "reaction_10090349", "reaction_10073557", "reaction_10087597", "reaction_10090409", "reaction_10047378", "reaction_10057735", "reaction_10051907", "reaction_10073011", "reaction_10065227", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10039209", "reaction_10069456", "reaction_10071526", "reaction_10033926", "reaction_10090098", "reaction_10061458", "reaction_10083483", "reaction_10073071", "reaction_10067362", "reaction_10043877", "reaction_10043832", "reaction_10057337", "reaction_10047206", "reaction_10072138", "reaction_10069448", "reaction_10090925", "reaction_10091878", "reaction_10090091", "reaction_10041649", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10074129", "reaction_10057151", "reaction_10046731", "reaction_10057872", "reaction_10083951", "reaction_10036148", "reaction_10092380", "reaction_10047947", "reaction_10041851", "reaction_10039671", "reaction_10090727", "reaction_10068707", "reaction_10037330", "reaction_10090971", "reaction_10048304", "reaction_10071659", "reaction_10069647", "reaction_10040303", "reaction_10075906", "reaction_10073547", "reaction_10073175", "reaction_10092392", "reaction_10084542", "reaction_10072944", "reaction_10040753", "reaction_10038450", "reaction_10092022", "reaction_10072225", "reaction_10072933", "reaction_10090115", "reaction_10090712", "reaction_10071262", "reaction_10041640", "reaction_10071330", "reaction_10060556", "reaction_10045362", "reaction_10057867", "reaction_10068095", "reaction_10092031", "reaction_10073561", "reaction_10091175", "reaction_10073231", "reaction_10071691", "reaction_10073244", "reaction_10076198", "reaction_10058480", "reaction_10073028", "reaction_10073159", "reaction_10072927", "reaction_10073215", "reaction_10049615", "reaction_10073014", "reaction_10091595", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10039667", "reaction_10040323", "reaction_10049643", "reaction_10073127", "reaction_10063342", "reaction_10073087", "reaction_10047332", "reaction_10038918", "reaction_10090567", "reaction_10047862", "reaction_10047552", "reaction_10073842", "reaction_10083676", "reaction_10036959", "reaction_10073242", "reaction_10091479", "reaction_10086565", "reaction_10073166", "reaction_10039658", "reaction_10074146", "reaction_10043753", "reaction_10090960", "reaction_10047870", "reaction_10047868", "reaction_10075256", "reaction_10057264", "reaction_10090077", "reaction_10049681", "reaction_10073152", "reaction_10089197", "reaction_10045016", "reaction_10035507", "reaction_10083558", "reaction_10046583", "reaction_10073140", "reaction_10048170", "reaction_10057712", "reaction_10040460", "reaction_10072931", "reaction_10092370", "reaction_10086662", "reaction_10046773", "reaction_10036590", "reaction_10059152", "reaction_10072913", "reaction_10047238", "reaction_10092055", "reaction_10073047", "reaction_10067895", "reaction_10039711", "reaction_10043129", "reaction_10057188", "reaction_10081580", "reaction_10089937", "reaction_10072979", "reaction_10072220", "reaction_10089211", "reaction_10089207", "reaction_10041333", "reaction_10069896", "reaction_10051217", "reaction_10043311", "reaction_10072993", "reaction_10091580", "reaction_10040451", "reaction_10039200", "reaction_10091994", "reaction_10090125", "reaction_10048174", "reaction_10040462", "reaction_10063380", "reaction_10053213", "reaction_10042860", "reaction_10090968", "reaction_10075063", "reaction_10073077", "reaction_10090428", "reaction_10075205", "reaction_10041629", "reaction_10083707", "reaction_10057329", "reaction_10072154", "reaction_10083726", "reaction_10057252", "reaction_10053082", "reaction_10091548", "reaction_10047860", "reaction_10091534", "reaction_10076743", "reaction_10087373", "reaction_10091037", "reaction_10073577", "reaction_10069872", "reaction_10073031", "reaction_10040277", "reaction_10073872", "reaction_10071524", "reaction_10048172", "reaction_10047394", "reaction_10091260", "reaction_10089985", "reaction_10071541", "reaction_10083690", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043461", "reaction_10075065", "reaction_10090722", "reaction_10073108", "reaction_10084702", "reaction_10089228", "reaction_10069664", "reaction_10073225", "reaction_10076229", "reaction_10048270", "reaction_10049639", "reaction_10039270", "reaction_10057314", "reaction_10058478", "reaction_10070651", "reaction_10089761", "reaction_10091929", "reaction_10070645", "reaction_10047823", "reaction_10083581", "reaction_10083672", "reaction_10091568", "reaction_10057854", "reaction_10048176", "reaction_10057695", "reaction_10039690", "reaction_10072909", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10037964", "reaction_10090954", "reaction_10073844", "reaction_10087370", "reaction_10068923", "reaction_10080870", "reaction_10083477", "reaction_10073328", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10083622", "reaction_10040453", "reaction_10047989", "reaction_10045156", "reaction_10063305", "reaction_10045094", "reaction_10075218", "reaction_10040495", "reaction_10044472", "reaction_10068078", "reaction_10057740", "reaction_10068704", "reaction_10090571", "reaction_10049637", "reaction_10073240", "reaction_10073806", "reaction_10073145", "reaction_10090456", "reaction_10057175", "reaction_10063849", "reaction_10043739", "reaction_10068088", "reaction_10049659", "reaction_10088496", "reaction_10091763", "reaction_10070931", "reaction_10073199", "reaction_10063408", "reaction_10072081", "reaction_10070594", "reaction_10040386", "reaction_10083729", "reaction_10092394", "reaction_10075251", "reaction_10039155", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10072630", "reaction_10073037", "reaction_10084067", "reaction_10073237", "reaction_10089217", "reaction_10040720", "reaction_10083684", "reaction_10041470", "reaction_10073136", "reaction_10067202", "reaction_10067908", "reaction_10039664", "reaction_10057692", "reaction_10057845", "reaction_10091529", "reaction_10089888", "reaction_10045196", "reaction_10067348", "reaction_10061480", "reaction_10091515", "reaction_10046733", "reaction_10083487", "reaction_10090011", "reaction_10091490", "reaction_10072920", "reaction_10070589", "reaction_10037332", "reaction_10078536", "reaction_10089930", "reaction_10041657", "reaction_10092208", "reaction_10069595", "reaction_10070615", "reaction_10057298", "reaction_10084466", "reaction_10073917", "reaction_10047380", "reaction_10090834", "reaction_10063329", "reaction_10073493", "reaction_10074148", "reaction_10072199", "reaction_10057166", "reaction_10073097", "reaction_10092314", "reaction_10047224", "reaction_10073156", "reaction_10072713" ] }, "R-BTA-392499": { "id": "pathway_10092572", "reactome": "R-BTA-392499", "name": "Metabolism of proteins", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10034383", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10074707", "reaction_10081490", "reaction_10050169", "reaction_10049811", "reaction_10048461", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10091124", "reaction_10043698", "reaction_10088807", "reaction_10088922", "reaction_10069329", "reaction_10069498", "reaction_10034224", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10046602", "reaction_10048465", "reaction_10082038", "reaction_10074857", "reaction_10083380", "reaction_10087883", "reaction_10034387", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10075023", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10038107", "reaction_10074833", "reaction_10077363", "reaction_10091120", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10075095", "reaction_10077034", "reaction_10048761", "reaction_10091056", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10075125", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10034905", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10049392", "reaction_10034855", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10083808", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10046723", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10048429", "reaction_10076119", "reaction_10048003", "reaction_10056074", "reaction_10076773", "reaction_10045744", "reaction_10077331", "reaction_10082045", "reaction_10077947", "reaction_10049831", "reaction_10038408", "reaction_10074686", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10049385", "reaction_10074863", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10085865", "reaction_10083231", "reaction_10076610", "reaction_10038082", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10075105", "reaction_10049789", "reaction_10046621", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10048380", "reaction_10076586", "reaction_10040933", "reaction_10048407", "reaction_10060894", "reaction_10046604", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10034365", "reaction_10088734", "reaction_10045696", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10075086", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10045736", "reaction_10075084", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10075019", "reaction_10048958", "reaction_10087848", "reaction_10074869", "reaction_10045694" ] }, "R-BTA-190236": { "id": "pathway_10093176", "reactome": "R-BTA-190236", "name": "Signaling by FGFR", "reactions": [ "reaction_10072979", "reaction_10073147", "reaction_10057327", "reaction_10040769", "reaction_10072993", "reaction_10040744", "reaction_10040779", "reaction_10073077", "reaction_10073234", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10053082", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10072999", "reaction_10087373", "reaction_10073102", "reaction_10073001", "reaction_10073031", "reaction_10072957", "reaction_10073184", "reaction_10073119", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10072946", "reaction_10073326", "reaction_10072939", "reaction_10073108", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10073225", "reaction_10057314", "reaction_10073122", "reaction_10040696", "reaction_10073133", "reaction_10073011", "reaction_10073044", "reaction_10073228", "reaction_10072909", "reaction_10057704", "reaction_10087370", "reaction_10040773", "reaction_10073328", "reaction_10073071", "reaction_10057337", "reaction_10073041", "reaction_10040782", "reaction_10073222", "reaction_10072929", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10072976", "reaction_10073199", "reaction_10073004", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10073237", "reaction_10073246", "reaction_10040720", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10073215", "reaction_10073014", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10073019", "reaction_10072935", "reaction_10072920", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10073242", "reaction_10087367", "reaction_10073166", "reaction_10083935", "reaction_10057707", "reaction_10040704", "reaction_10073152", "reaction_10073140", "reaction_10072931", "reaction_10087376", "reaction_10073097", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10057302" ] }, "R-BTA-196854": { "id": "pathway_10092520", "reactome": "R-BTA-196854", "name": "Metabolism of vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10085855", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10038427", "reaction_10066401", "reaction_10041772", "reaction_10081928", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10090493", "reaction_10041840", "reaction_10066249", "reaction_10041790", "reaction_10069948", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10058514", "reaction_10053350", "reaction_10086748", "reaction_10054395", "reaction_10041753", "reaction_10058524", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10070971", "reaction_10058511", "reaction_10081977", "reaction_10081935", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10054375", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10058785", "reaction_10065445", "reaction_10066247", "reaction_10065437", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10086750", "reaction_10053363", "reaction_10065441", "reaction_10081984", "reaction_10064591", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10085853", "reaction_10046968", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-1280215": { "id": "pathway_10093068", "reactome": "R-BTA-1280215", "name": "Cytokine Signaling in Immune system", "reactions": [ "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10051936", "reaction_10052213", "reaction_10056127", "reaction_10052321", "reaction_10050196", "reaction_10056268", "reaction_10051762", "reaction_10052254", "reaction_10089466", "reaction_10074266", "reaction_10054791", "reaction_10051696", "reaction_10089506", "reaction_10056205", "reaction_10089442", "reaction_10092165", "reaction_10089691", "reaction_10050231", "reaction_10070719", "reaction_10042826", "reaction_10077790", "reaction_10051966", "reaction_10052196", "reaction_10073690", "reaction_10050011", "reaction_10089329", "reaction_10092257", "reaction_10090919", "reaction_10051786", "reaction_10090844", "reaction_10092043", "reaction_10077843", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10087783", "reaction_10087763", "reaction_10089480", "reaction_10052294", "reaction_10074280", "reaction_10043488", "reaction_10074314", "reaction_10052337", "reaction_10077874", "reaction_10051774", "reaction_10092108", "reaction_10049970", "reaction_10052217", "reaction_10051196", "reaction_10089291", "reaction_10087787", "reaction_10089341", "reaction_10087671", "reaction_10052325", "reaction_10087789", "reaction_10083537", "reaction_10089843", "reaction_10089267", "reaction_10089615", "reaction_10092139", "reaction_10055958", "reaction_10089625", "reaction_10089321", "reaction_10077945", "reaction_10089333", "reaction_10089516", "reaction_10077422", "reaction_10056170", "reaction_10092126", "reaction_10056110", "reaction_10071975", "reaction_10051737", "reaction_10074340", "reaction_10071982", "reaction_10089431", "reaction_10089540", "reaction_10073757", "reaction_10087732", "reaction_10091757", "reaction_10056172", "reaction_10050218", "reaction_10051095", "reaction_10087780", "reaction_10087795", "reaction_10052067", "reaction_10090031", "reaction_10089536", "reaction_10056287", "reaction_10052210", "reaction_10089251", "reaction_10057834", "reaction_10049946", "reaction_10050254", "reaction_10089819", "reaction_10052343", "reaction_10051962", "reaction_10091747", "reaction_10091731", "reaction_10041950", "reaction_10089523", "reaction_10087774", "reaction_10089253", "reaction_10089530", "reaction_10054779", "reaction_10089538", "reaction_10050192", "reaction_10056130", "reaction_10056188", "reaction_10092173", "reaction_10091723", "reaction_10090027", "reaction_10074312", "reaction_10077455", "reaction_10089591", "reaction_10056178", "reaction_10051818", "reaction_10077633", "reaction_10052735", "reaction_10089311", "reaction_10055955", "reaction_10089455", "reaction_10056199", "reaction_10089446", "reaction_10057823", "reaction_10074318", "reaction_10056289", "reaction_10050256", "reaction_10056194", "reaction_10055946", "reaction_10055967", "reaction_10056176", "reaction_10089453", "reaction_10089444", "reaction_10090916", "reaction_10089689", "reaction_10092195", "reaction_10074320", "reaction_10052236", "reaction_10043867", "reaction_10077723", "reaction_10089349", "reaction_10060694", "reaction_10052147", "reaction_10051780", "reaction_10056132", "reaction_10084305", "reaction_10051748", "reaction_10073765", "reaction_10051771", "reaction_10092183", "reaction_10089621", "reaction_10089511", "reaction_10050054", "reaction_10087338", "reaction_10092151", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10091725", "reaction_10056207", "reaction_10092147", "reaction_10052229", "reaction_10087663", "reaction_10050028", "reaction_10050623", "reaction_10076165", "reaction_10056315", "reaction_10089542", "reaction_10092033", "reaction_10056123", "reaction_10050527", "reaction_10052323", "reaction_10050208", "reaction_10089703", "reaction_10087766", "reaction_10060730", "reaction_10056335", "reaction_10049928", "reaction_10073708", "reaction_10050428", "reaction_10083522", "reaction_10071948", "reaction_10051792", "reaction_10060412", "reaction_10089696", "reaction_10039508", "reaction_10052159", "reaction_10050420", "reaction_10072030", "reaction_10087650", "reaction_10056283", "reaction_10052327", "reaction_10052233", "reaction_10089736", "reaction_10092143", "reaction_10051949", "reaction_10089269", "reaction_10076237", "reaction_10092159", "reaction_10052189", "reaction_10074308", "reaction_10089597", "reaction_10056297", "reaction_10089427", "reaction_10088498", "reaction_10089331", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074306", "reaction_10074310", "reaction_10092141", "reaction_10089812", "reaction_10049983", "reaction_10052240", "reaction_10089595", "reaction_10054524", "reaction_10092137", "reaction_10077870", "reaction_10050619", "reaction_10056102", "reaction_10049721", "reaction_10087726", "reaction_10092040", "reaction_10085017", "reaction_10051954", "reaction_10057836", "reaction_10077764", "reaction_10050024", "reaction_10089363", "reaction_10088519", "reaction_10052302" ] }, "R-BTA-1280218": { "id": "pathway_10093314", "reactome": "R-BTA-1280218", "name": "Adaptive Immune System", "reactions": [ "reaction_10075009", "reaction_10065009", "reaction_10043302", "reaction_10055821", "reaction_10053213", "reaction_10065051", "reaction_10046932", "reaction_10046807", "reaction_10043300", "reaction_10055448", "reaction_10046888", "reaction_10083967", "reaction_10046909", "reaction_10042129", "reaction_10043262", "reaction_10043212", "reaction_10042253", "reaction_10056805", "reaction_10064219", "reaction_10043659", "reaction_10055783", "reaction_10055491", "reaction_10065055", "reaction_10087823", "reaction_10043274", "reaction_10057004", "reaction_10063972", "reaction_10047530", "reaction_10084658", "reaction_10056910", "reaction_10043219", "reaction_10065227", "reaction_10042623", "reaction_10075923", "reaction_10083959", "reaction_10046787", "reaction_10043182", "reaction_10055453", "reaction_10055444", "reaction_10074901", "reaction_10046903", "reaction_10065011", "reaction_10043298", "reaction_10043304", "reaction_10064068", "reaction_10084867", "reaction_10043270", "reaction_10056912", "reaction_10046959", "reaction_10064214", "reaction_10091743", "reaction_10055451", "reaction_10043244", "reaction_10064221", "reaction_10056982", "reaction_10056914", "reaction_10074993", "reaction_10056903", "reaction_10074899", "reaction_10055431", "reaction_10065019", "reaction_10076963", "reaction_10065021", "reaction_10055817", "reaction_10043193", "reaction_10043252", "reaction_10087807", "reaction_10055460", "reaction_10046907", "reaction_10046943", "reaction_10056835", "reaction_10047519", "reaction_10054866", "reaction_10091817", "reaction_10046811", "reaction_10052471", "reaction_10084672", "reaction_10046822", "reaction_10043225", "reaction_10042786", "reaction_10052466", "reaction_10084401", "reaction_10045016", "reaction_10043241", "reaction_10042635", "reaction_10046834", "reaction_10064118", "reaction_10047536", "reaction_10046951", "reaction_10064277", "reaction_10084865", "reaction_10055819", "reaction_10056239" ] }, "R-BTA-71387": { "id": "pathway_10092456", "reactome": "R-BTA-71387", "name": "Metabolism of carbohydrates", "reactions": [ "reaction_10039887", "reaction_10077793", "reaction_10033592", "reaction_10062697", "reaction_10036903", "reaction_10073438", "reaction_10034118", "reaction_10090645", "reaction_10063216", "reaction_10088737", "reaction_10064393", "reaction_10063807", "reaction_10051589", "reaction_10060634", "reaction_10063485", "reaction_10062701", "reaction_10091289", "reaction_10034013", "reaction_10063508", "reaction_10061251", "reaction_10064353", "reaction_10064597", "reaction_10033561", "reaction_10060829", "reaction_10034157", "reaction_10033638", "reaction_10063022", "reaction_10041878", "reaction_10061395", "reaction_10033620", "reaction_10063249", "reaction_10063510", "reaction_10063610", "reaction_10061651", "reaction_10080765", "reaction_10060741", "reaction_10060827", "reaction_10061612", "reaction_10090854", "reaction_10060295", "reaction_10045692", "reaction_10063010", "reaction_10078710", "reaction_10064355", "reaction_10090851", "reaction_10042801", "reaction_10090772", "reaction_10080747", "reaction_10060031", "reaction_10034071", "reaction_10067610", "reaction_10076815", "reaction_10067254", "reaction_10045043", "reaction_10089230", "reaction_10080756", "reaction_10050637", "reaction_10063633", "reaction_10090620", "reaction_10067240", "reaction_10034041", "reaction_10045029", "reaction_10063603", "reaction_10090696", "reaction_10045050", "reaction_10090638", "reaction_10034944", "reaction_10063532", "reaction_10090856", "reaction_10091286", "reaction_10033718", "reaction_10041885", "reaction_10068748", "reaction_10064595", "reaction_10063520", "reaction_10067247", "reaction_10061642", "reaction_10090703", "reaction_10088744", "reaction_10060685", "reaction_10067639", "reaction_10063801", "reaction_10091291", "reaction_10033611", "reaction_10090799", "reaction_10033629", "reaction_10063803", "reaction_10067634", "reaction_10039890", "reaction_10091293", "reaction_10048727", "reaction_10060678", "reaction_10072894", "reaction_10060825", "reaction_10060625", "reaction_10033570", "reaction_10090611", "reaction_10063232", "reaction_10063805", "reaction_10061402", "reaction_10063014", "reaction_10062508", "reaction_10034043", "reaction_10062463", "reaction_10034238", "reaction_10062674", "reaction_10090867", "reaction_10034032", "reaction_10062984", "reaction_10033579", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10072825", "reaction_10061350", "reaction_10060293", "reaction_10090802", "reaction_10060671", "reaction_10062655", "reaction_10064593", "reaction_10090822", "reaction_10033594", "reaction_10063477", "reaction_10090819", "reaction_10060842", "reaction_10088898", "reaction_10084129", "reaction_10073431", "reaction_10067648", "reaction_10060285", "reaction_10067622", "reaction_10068755", "reaction_10063530", "reaction_10090631", "reaction_10090774", "reaction_10051570", "reaction_10067644", "reaction_10063586", "reaction_10034138", "reaction_10090797", "reaction_10034140", "reaction_10083115", "reaction_10064391" ] }, "R-BTA-168249": { "id": "pathway_10093004", "reactome": "R-BTA-168249", "name": "Innate Immune System", "reactions": [ "reaction_10063376", "reaction_10050196", "reaction_10066551", "reaction_10078759", "reaction_10066144", "reaction_10066102", "reaction_10056531", "reaction_10053134", "reaction_10072364", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10066536", "reaction_10080844", "reaction_10063374", "reaction_10067223", "reaction_10077921", "reaction_10066094", "reaction_10072388", "reaction_10066141", "reaction_10050231", "reaction_10056088", "reaction_10042826", "reaction_10065402", "reaction_10081265", "reaction_10072045", "reaction_10065413", "reaction_10063353", "reaction_10090400", "reaction_10081510", "reaction_10039217", "reaction_10061502", "reaction_10051836", "reaction_10083100", "reaction_10080435", "reaction_10065407", "reaction_10081397", "reaction_10067233", "reaction_10080842", "reaction_10053048", "reaction_10072057", "reaction_10056416", "reaction_10043488", "reaction_10086405", "reaction_10072011", "reaction_10082012", "reaction_10056084", "reaction_10083106", "reaction_10040197", "reaction_10081385", "reaction_10085369", "reaction_10082967", "reaction_10039465", "reaction_10060783", "reaction_10053058", "reaction_10079949", "reaction_10079199", "reaction_10054678", "reaction_10071975", "reaction_10071982", "reaction_10061657", "reaction_10050218", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10043182", "reaction_10080063", "reaction_10050254", "reaction_10065517", "reaction_10066082", "reaction_10077924", "reaction_10041950", "reaction_10070906", "reaction_10072383", "reaction_10066127", "reaction_10060785", "reaction_10039778", "reaction_10072374", "reaction_10072002", "reaction_10066180", "reaction_10065894", "reaction_10084706", "reaction_10066151", "reaction_10050192", "reaction_10066059", "reaction_10058492", "reaction_10066238", "reaction_10081559", "reaction_10081404", "reaction_10067229", "reaction_10072061", "reaction_10081406", "reaction_10081410", "reaction_10066080", "reaction_10084683", "reaction_10058486", "reaction_10078929", "reaction_10066052", "reaction_10081943", "reaction_10079653", "reaction_10066147", "reaction_10050256", "reaction_10067225", "reaction_10066120", "reaction_10080831", "reaction_10084636", "reaction_10061174", "reaction_10054649", "reaction_10055971", "reaction_10066172", "reaction_10065642", "reaction_10079391", "reaction_10060773", "reaction_10080719", "reaction_10081905", "reaction_10056539", "reaction_10082977", "reaction_10053122", "reaction_10081432", "reaction_10072053", "reaction_10082004", "reaction_10084020", "reaction_10090019", "reaction_10092318", "reaction_10077926", "reaction_10065491", "reaction_10072006", "reaction_10058388", "reaction_10041863", "reaction_10082008", "reaction_10066559", "reaction_10066880", "reaction_10039782", "reaction_10039481", "reaction_10050208", "reaction_10054736", "reaction_10053095", "reaction_10071948", "reaction_10047907", "reaction_10082183", "reaction_10056082", "reaction_10067231", "reaction_10060759", "reaction_10039508", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10077919", "reaction_10063368", "reaction_10065388", "reaction_10056090", "reaction_10084322", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10058456", "reaction_10066168", "reaction_10066608", "reaction_10066532", "reaction_10053046", "reaction_10087797", "reaction_10081506", "reaction_10072392", "reaction_10081085", "reaction_10077904", "reaction_10072395" ] }, "R-BTA-1266738": { "id": "pathway_10093388", "reactome": "R-BTA-1266738", "name": "Developmental Biology", "reactions": [ "reaction_10081917", "reaction_10081921", "reaction_10084311", "reaction_10089713", "reaction_10048951", "reaction_10045244", "reaction_10069146", "reaction_10083835", "reaction_10091007", "reaction_10047763", "reaction_10083824", "reaction_10084141", "reaction_10074613", "reaction_10085757", "reaction_10084153", "reaction_10074641", "reaction_10047735", "reaction_10069221", "reaction_10069157", "reaction_10069223", "reaction_10044090", "reaction_10045509", "reaction_10047618", "reaction_10069188", "reaction_10084135", "reaction_10084309", "reaction_10069418", "reaction_10045517", "reaction_10084393", "reaction_10043671", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10047455", "reaction_10047659", "reaction_10047717", "reaction_10084326", "reaction_10069285", "reaction_10084330", "reaction_10045224", "reaction_10083741", "reaction_10084187", "reaction_10045236", "reaction_10050085", "reaction_10047449", "reaction_10069192", "reaction_10069121", "reaction_10089397", "reaction_10091009", "reaction_10084185", "reaction_10069159", "reaction_10084379", "reaction_10084131", "reaction_10083743", "reaction_10085755", "reaction_10084149", "reaction_10082871", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10069435", "reaction_10069144", "reaction_10077943", "reaction_10047458", "reaction_10069131", "reaction_10084196", "reaction_10069226", "reaction_10050116", "reaction_10081857", "reaction_10049024", "reaction_10074603", "reaction_10090179", "reaction_10081915", "reaction_10081861", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10047753", "reaction_10084194", "reaction_10084313" ] }, "R-BTA-422475": { "id": "pathway_10093384", "reactome": "R-BTA-422475", "name": "Axon guidance", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10084393", "reaction_10084185", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-1483206": { "id": "pathway_10092668", "reactome": "R-BTA-1483206", "name": "Glycerophospholipid biosynthesis", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10035786", "reaction_10058913", "reaction_10085808", "reaction_10058998", "reaction_10085798", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10084526", "reaction_10071344", "reaction_10059035", "reaction_10058996", "reaction_10058970", "reaction_10059018", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10058834", "reaction_10085340", "reaction_10058874", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10059073", "reaction_10059114", "reaction_10058892", "reaction_10059014", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10085024", "reaction_10058899", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10086064", "reaction_10058980", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10058841", "reaction_10059026", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10059101", "reaction_10058948", "reaction_10058985", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10076824" ] }, "R-BTA-8953897": { "id": "pathway_10092556", "reactome": "R-BTA-8953897", "name": "Cellular responses to external stimuli", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10073468", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10073460", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10073446", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10073481", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273", "reaction_10073464" ] }, "R-BTA-425407": { "id": "pathway_10092730", "reactome": "R-BTA-425407", "name": "SLC-mediated transmembrane transport", "reactions": [ "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10049371", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10049319", "reaction_10045494", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10049080", "reaction_10044978", "reaction_10051892", "reaction_10085907", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10045501", "reaction_10049464", "reaction_10045473", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10048795", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10051547", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10044962", "reaction_10072522", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10048504", "reaction_10049440", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10049083", "reaction_10048768", "reaction_10049378", "reaction_10049869", "reaction_10044941", "reaction_10048491", "reaction_10051276", "reaction_10044934", "reaction_10089029", "reaction_10049385", "reaction_10051545", "reaction_10044955", "reaction_10085384", "reaction_10051587", "reaction_10048754", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10036297", "reaction_10071001", "reaction_10051879", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10049053", "reaction_10048821", "reaction_10049628", "reaction_10049447", "reaction_10071003", "reaction_10051866", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-199991": { "id": "pathway_10093212", "reactome": "R-BTA-199991", "name": "Membrane Trafficking", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10076775", "reaction_10043649", "reaction_10076590", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10084261", "reaction_10086209", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10083342", "reaction_10083767", "reaction_10040961", "reaction_10076778", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-71291": { "id": "pathway_10092486", "reactome": "R-BTA-71291", "name": "Metabolism of amino acids and derivatives", "reactions": [ "reaction_10060216", "reaction_10033849", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10076984", "reaction_10033778", "reaction_10090172", "reaction_10076459", "reaction_10052043", "reaction_10034004", "reaction_10043978", "reaction_10090175", "reaction_10051185", "reaction_10033953", "reaction_10078701", "reaction_10052030", "reaction_10045036", "reaction_10054601", "reaction_10043980", "reaction_10060207", "reaction_10085381", "reaction_10060252", "reaction_10033788", "reaction_10086033", "reaction_10078402", "reaction_10090015", "reaction_10090679", "reaction_10090681", "reaction_10064346", "reaction_10044784", "reaction_10033681", "reaction_10054611", "reaction_10078529", "reaction_10044776", "reaction_10043956", "reaction_10033755", "reaction_10043924", "reaction_10076261", "reaction_10060250", "reaction_10077864", "reaction_10043917", "reaction_10044851", "reaction_10077758", "reaction_10060264", "reaction_10033797", "reaction_10089850", "reaction_10042847", "reaction_10033962", "reaction_10060234", "reaction_10086371", "reaction_10033997", "reaction_10045029", "reaction_10076974", "reaction_10043933", "reaction_10033718", "reaction_10047022", "reaction_10060255", "reaction_10090162", "reaction_10041894", "reaction_10033737", "reaction_10043948", "reaction_10044794", "reaction_10044828", "reaction_10033824", "reaction_10033697", "reaction_10033728", "reaction_10077458", "reaction_10044837", "reaction_10033706", "reaction_10078366", "reaction_10090647", "reaction_10054585", "reaction_10076450", "reaction_10033840", "reaction_10052046", "reaction_10065455", "reaction_10087455", "reaction_10052027", "reaction_10033935", "reaction_10033833", "reaction_10044835", "reaction_10077124", "reaction_10078575", "reaction_10076360", "reaction_10057684", "reaction_10054620", "reaction_10043986", "reaction_10044801", "reaction_10044844", "reaction_10033969", "reaction_10090671", "reaction_10083204", "reaction_10057032", "reaction_10060361", "reaction_10057023", "reaction_10073477", "reaction_10033716", "reaction_10033757", "reaction_10060228", "reaction_10033979", "reaction_10033770", "reaction_10052040", "reaction_10052056", "reaction_10090155", "reaction_10089959", "reaction_10076441", "reaction_10033806", "reaction_10033944", "reaction_10033690", "reaction_10076406", "reaction_10078393", "reaction_10042838", "reaction_10047019", "reaction_10060218", "reaction_10051165", "reaction_10033988", "reaction_10077444", "reaction_10051198", "reaction_10077435", "reaction_10076130", "reaction_10090013", "reaction_10060231", "reaction_10077453" ] }, "R-BTA-1640170": { "id": "pathway_10092414", "reactome": "R-BTA-1640170", "name": "Cell Cycle", "reactions": [ "reaction_10051463", "reaction_10040542", "reaction_10084051", "reaction_10035745", "reaction_10065938", "reaction_10040576", "reaction_10040503", "reaction_10057808", "reaction_10039612", "reaction_10070705", "reaction_10091661", "reaction_10076341", "reaction_10065177", "reaction_10065201", "reaction_10091145", "reaction_10083565", "reaction_10040183", "reaction_10084102", "reaction_10065708", "reaction_10084047", "reaction_10087503", "reaction_10057812", "reaction_10087487", "reaction_10065095", "reaction_10038033", "reaction_10091685", "reaction_10038949", "reaction_10056602", "reaction_10064904", "reaction_10066487", "reaction_10069491", "reaction_10039614", "reaction_10056616", "reaction_10051465", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10057804", "reaction_10066489", "reaction_10040355", "reaction_10084096", "reaction_10091132", "reaction_10033512", "reaction_10065572", "reaction_10084090", "reaction_10091663", "reaction_10065563", "reaction_10040521", "reaction_10038947", "reaction_10051451", "reaction_10057821", "reaction_10064733", "reaction_10035747", "reaction_10078408", "reaction_10087385", "reaction_10084206", "reaction_10040059", "reaction_10065726", "reaction_10091634", "reaction_10033504", "reaction_10091658", "reaction_10033473", "reaction_10039801", "reaction_10033535", "reaction_10066345", "reaction_10084043", "reaction_10091656", "reaction_10033466", "reaction_10057816", "reaction_10051461", "reaction_10074695", "reaction_10091141", "reaction_10084028", "reaction_10065794", "reaction_10081470", "reaction_10087394", "reaction_10038035", "reaction_10083558", "reaction_10074692", "reaction_10038540", "reaction_10038534", "reaction_10066324" ] }, "R-BTA-1483257": { "id": "pathway_10092670", "reactome": "R-BTA-1483257", "name": "Phospholipid metabolism", "reactions": [ "reaction_10035812", "reaction_10059066", "reaction_10082931", "reaction_10077777", "reaction_10058894", "reaction_10058871", "reaction_10085826", "reaction_10083572", "reaction_10059849", "reaction_10060614", "reaction_10058983", "reaction_10058880", "reaction_10058993", "reaction_10059044", "reaction_10060569", "reaction_10035786", "reaction_10082934", "reaction_10058913", "reaction_10060597", "reaction_10085808", "reaction_10060600", "reaction_10058998", "reaction_10085798", "reaction_10060590", "reaction_10059856", "reaction_10058826", "reaction_10058858", "reaction_10058916", "reaction_10060579", "reaction_10084526", "reaction_10071344", "reaction_10060448", "reaction_10060429", "reaction_10083369", "reaction_10083211", "reaction_10059035", "reaction_10082155", "reaction_10058996", "reaction_10058970", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10060572", "reaction_10059063", "reaction_10058961", "reaction_10058829", "reaction_10060518", "reaction_10058834", "reaction_10085340", "reaction_10082152", "reaction_10058874", "reaction_10085784", "reaction_10058809", "reaction_10076792", "reaction_10058908", "reaction_10059858", "reaction_10058896", "reaction_10059091", "reaction_10059006", "reaction_10076994", "reaction_10060588", "reaction_10060476", "reaction_10085843", "reaction_10060498", "reaction_10059073", "reaction_10060535", "reaction_10059114", "reaction_10060537", "reaction_10058892", "reaction_10082147", "reaction_10060516", "reaction_10059014", "reaction_10082136", "reaction_10058945", "reaction_10085310", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10059002", "reaction_10059130", "reaction_10058819", "reaction_10059141", "reaction_10058923", "reaction_10060468", "reaction_10085780", "reaction_10085024", "reaction_10058899", "reaction_10060501", "reaction_10060553", "reaction_10058955", "reaction_10059000", "reaction_10058877", "reaction_10083092", "reaction_10088026", "reaction_10086248", "reaction_10058910", "reaction_10088649", "reaction_10083800", "reaction_10060556", "reaction_10044540", "reaction_10059121", "reaction_10059094", "reaction_10085775", "reaction_10086064", "reaction_10058980", "reaction_10060550", "reaction_10058990", "reaction_10058943", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058841", "reaction_10059026", "reaction_10060483", "reaction_10058934", "reaction_10059004", "reaction_10058885", "reaction_10058812", "reaction_10059860", "reaction_10059853", "reaction_10060595", "reaction_10059101", "reaction_10060574", "reaction_10058948", "reaction_10058985", "reaction_10060558", "reaction_10059016", "reaction_10059851", "reaction_10051264", "reaction_10059082", "reaction_10077004", "reaction_10059150", "reaction_10060461", "reaction_10076824" ] }, "R-BTA-9675108": { "id": "pathway_10093386", "reactome": "R-BTA-9675108", "name": "Nervous system development", "reactions": [ "reaction_10084326", "reaction_10069285", "reaction_10085755", "reaction_10084153", "reaction_10084149", "reaction_10047735", "reaction_10084330", "reaction_10045224", "reaction_10048935", "reaction_10084190", "reaction_10084352", "reaction_10084187", "reaction_10069221", "reaction_10069144", "reaction_10069435", "reaction_10045236", "reaction_10047458", "reaction_10069223", "reaction_10069157", "reaction_10084311", "reaction_10069131", "reaction_10084196", "reaction_10084194", "reaction_10045509", "reaction_10047618", "reaction_10089713", "reaction_10048951", "reaction_10069188", "reaction_10084135", "reaction_10069226", "reaction_10084309", "reaction_10045244", "reaction_10069146", "reaction_10069418", "reaction_10047449", "reaction_10069192", "reaction_10045517", "reaction_10049024", "reaction_10089397", "reaction_10069121", "reaction_10090179", "reaction_10091009", "reaction_10084393", "reaction_10084185", "reaction_10091007", "reaction_10047763", "reaction_10043671", "reaction_10069159", "reaction_10069253", "reaction_10084198", "reaction_10069148", "reaction_10069243", "reaction_10069194", "reaction_10084169", "reaction_10084141", "reaction_10047753", "reaction_10047455", "reaction_10047659", "reaction_10084379", "reaction_10084131", "reaction_10047717", "reaction_10085757", "reaction_10084313" ] }, "R-BTA-69278": { "id": "pathway_10092412", "reactome": "R-BTA-69278", "name": "Cell Cycle, Mitotic", "reactions": [ "reaction_10057804", "reaction_10084102", "reaction_10039801", "reaction_10066489", "reaction_10065708", "reaction_10084047", "reaction_10040542", "reaction_10066345", "reaction_10040355", "reaction_10084096", "reaction_10087503", "reaction_10091132", "reaction_10084043", "reaction_10084051", "reaction_10035745", "reaction_10033512", "reaction_10065938", "reaction_10057812", "reaction_10065572", "reaction_10091656", "reaction_10087487", "reaction_10084090", "reaction_10033466", "reaction_10065095", "reaction_10057816", "reaction_10040576", "reaction_10040503", "reaction_10038033", "reaction_10065563", "reaction_10091141", "reaction_10084028", "reaction_10057808", "reaction_10039612", "reaction_10056602", "reaction_10070705", "reaction_10065794", "reaction_10033473", "reaction_10040521", "reaction_10087394", "reaction_10091661", "reaction_10057821", "reaction_10038035", "reaction_10064733", "reaction_10083558", "reaction_10087385", "reaction_10084206", "reaction_10065177", "reaction_10064904", "reaction_10066487", "reaction_10065201", "reaction_10069491", "reaction_10035747", "reaction_10065726", "reaction_10039614", "reaction_10091145", "reaction_10056616", "reaction_10091634", "reaction_10033504", "reaction_10083565", "reaction_10040183", "reaction_10084216", "reaction_10084214", "reaction_10057800", "reaction_10039852", "reaction_10091658", "reaction_10066324" ] }, "R-BTA-8957322": { "id": "pathway_10092930", "reactome": "R-BTA-8957322", "name": "Metabolism of steroids", "reactions": [ "reaction_10041308", "reaction_10041363", "reaction_10041297", "reaction_10041104", "reaction_10050650", "reaction_10077113", "reaction_10041359", "reaction_10081990", "reaction_10041323", "reaction_10041284", "reaction_10041186", "reaction_10084679", "reaction_10041321", "reaction_10041437", "reaction_10041671", "reaction_10041684", "reaction_10063560", "reaction_10041277", "reaction_10041319", "reaction_10041179", "reaction_10041477", "reaction_10076281", "reaction_10041500", "reaction_10041337", "reaction_10041377", "reaction_10044739", "reaction_10041721", "reaction_10041172", "reaction_10040904", "reaction_10041486", "reaction_10043885", "reaction_10041177", "reaction_10040913", "reaction_10043971", "reaction_10041386", "reaction_10041357", "reaction_10040881", "reaction_10041226", "reaction_10041347", "reaction_10041341", "reaction_10041415", "reaction_10081988", "reaction_10041310", "reaction_10041325", "reaction_10081986", "reaction_10041111", "reaction_10041170", "reaction_10041290", "reaction_10040895", "reaction_10041327", "reaction_10060346", "reaction_10041193", "reaction_10041206", "reaction_10083496", "reaction_10041664", "reaction_10041373", "reaction_10041293", "reaction_10043903", "reaction_10043910", "reaction_10041716", "reaction_10088928", "reaction_10085316", "reaction_10041412", "reaction_10063562", "reaction_10063564", "reaction_10041692", "reaction_10041484", "reaction_10041349", "reaction_10041379", "reaction_10092062", "reaction_10038347", "reaction_10041397", "reaction_10041493", "reaction_10041210", "reaction_10044741", "reaction_10041393", "reaction_10041345", "reaction_10041204", "reaction_10041367", "reaction_10040924", "reaction_10041339", "reaction_10041097", "reaction_10041301", "reaction_10041502", "reaction_10041299", "reaction_10041195", "reaction_10088926", "reaction_10041369", "reaction_10085806", "reaction_10041197", "reaction_10041343", "reaction_10041208", "reaction_10085291", "reaction_10041355", "reaction_10041365", "reaction_10040933", "reaction_10041424", "reaction_10041728", "reaction_10040892", "reaction_10092065", "reaction_10041351", "reaction_10041719", "reaction_10041371", "reaction_10041375", "reaction_10041269", "reaction_10041295", "reaction_10057880", "reaction_10041395", "reaction_10088019", "reaction_10041335", "reaction_10043964", "reaction_10041353", "reaction_10043984", "reaction_10041317", "reaction_10041361", "reaction_10041217", "reaction_10040922", "reaction_10051676" ] }, "R-BTA-372790": { "id": "pathway_10092780", "reactome": "R-BTA-372790", "name": "Signaling by GPCR", "reactions": [ "reaction_10037037", "reaction_10081580", "reaction_10047236", "reaction_10089211", "reaction_10089207", "reaction_10064915", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10037045", "reaction_10039676", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10047979", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10089224", "reaction_10048587", "reaction_10047334", "reaction_10046149", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10076743", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10037549", "reaction_10037022", "reaction_10083878", "reaction_10048370", "reaction_10047214", "reaction_10083880", "reaction_10039485", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10088942", "reaction_10084702", "reaction_10088940", "reaction_10089228", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10047498", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10064919", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10047823", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10089226", "reaction_10089167", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10037024", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10064910", "reaction_10041950", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10046534", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10048580", "reaction_10091825", "reaction_10048543", "reaction_10051656", "reaction_10046731", "reaction_10084016", "reaction_10083951", "reaction_10089222", "reaction_10045292", "reaction_10047947", "reaction_10049659", "reaction_10039671", "reaction_10047366", "reaction_10039674", "reaction_10091763", "reaction_10046729", "reaction_10037330", "reaction_10048304", "reaction_10088962", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10089217", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10037004", "reaction_10049478", "reaction_10048632", "reaction_10051667", "reaction_10048660", "reaction_10039664", "reaction_10049645", "reaction_10049615", "reaction_10043315", "reaction_10046917", "reaction_10047866", "reaction_10039653", "reaction_10047468", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10039667", "reaction_10049643", "reaction_10037332", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10047552", "reaction_10048178", "reaction_10089203", "reaction_10049657", "reaction_10048180", "reaction_10036959", "reaction_10086565", "reaction_10039658", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047956", "reaction_10047380", "reaction_10049681", "reaction_10089197", "reaction_10089214", "reaction_10067358", "reaction_10048170", "reaction_10036981", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10092055", "reaction_10039651", "reaction_10091247", "reaction_10045106" ] }, "R-BTA-3700989": { "id": "pathway_10092434", "reactome": "R-BTA-3700989", "name": "Transcriptional Regulation by TP53", "reactions": [ "reaction_10080722", "reaction_10066745", "reaction_10082931", "reaction_10066870", "reaction_10081380", "reaction_10081877", "reaction_10080738", "reaction_10078731", "reaction_10081291", "reaction_10033535", "reaction_10080730", "reaction_10081629", "reaction_10083072", "reaction_10082923", "reaction_10081323", "reaction_10033592", "reaction_10080789", "reaction_10081541", "reaction_10066764", "reaction_10046588", "reaction_10078349", "reaction_10033755", "reaction_10081522", "reaction_10034166", "reaction_10081278", "reaction_10080797", "reaction_10072591", "reaction_10081274", "reaction_10066704", "reaction_10082934", "reaction_10066684", "reaction_10088542", "reaction_10081293", "reaction_10038647", "reaction_10072550", "reaction_10081470", "reaction_10072614", "reaction_10081563", "reaction_10081602", "reaction_10066724", "reaction_10066670", "reaction_10072595", "reaction_10077955", "reaction_10066737", "reaction_10086155", "reaction_10076341", "reaction_10083092", "reaction_10081530", "reaction_10078474", "reaction_10083077", "reaction_10078408", "reaction_10072557", "reaction_10088546", "reaction_10081326", "reaction_10078720", "reaction_10078658", "reaction_10081499", "reaction_10081595", "reaction_10066712", "reaction_10088534", "reaction_10081305", "reaction_10081286", "reaction_10081622", "reaction_10081889", "reaction_10072571", "reaction_10080811", "reaction_10080457", "reaction_10081561" ] }, "R-BTA-388396": { "id": "pathway_10092778", "reactome": "R-BTA-388396", "name": "GPCR downstream signalling", "reactions": [ "reaction_10037037", "reaction_10043315", "reaction_10089211", "reaction_10039653", "reaction_10089207", "reaction_10064915", "reaction_10048580", "reaction_10037045", "reaction_10047468", "reaction_10039676", "reaction_10048543", "reaction_10088940", "reaction_10089228", "reaction_10051656", "reaction_10039667", "reaction_10084016", "reaction_10047979", "reaction_10047498", "reaction_10089224", "reaction_10089222", "reaction_10083951", "reaction_10047947", "reaction_10037332", "reaction_10047552", "reaction_10039671", "reaction_10089203", "reaction_10039674", "reaction_10064919", "reaction_10048587", "reaction_10036959", "reaction_10039664", "reaction_10047823", "reaction_10037330", "reaction_10039658", "reaction_10046149", "reaction_10088962", "reaction_10047956", "reaction_10076743", "reaction_10089226", "reaction_10089167", "reaction_10089214", "reaction_10089197", "reaction_10037024", "reaction_10048170", "reaction_10036981", "reaction_10089217", "reaction_10037549", "reaction_10037022", "reaction_10037004", "reaction_10048370", "reaction_10064910", "reaction_10041950", "reaction_10049478", "reaction_10039485", "reaction_10046534", "reaction_10048632", "reaction_10048660", "reaction_10092055", "reaction_10039651", "reaction_10051667", "reaction_10091247", "reaction_10088942" ] }, "R-BTA-194315": { "id": "pathway_10093368", "reactome": "R-BTA-194315", "name": "Signaling by Rho GTPases", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10072515", "reaction_10073503", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] }, "R-BTA-73857": { "id": "pathway_10092438", "reactome": "R-BTA-73857", "name": "RNA Polymerase II Transcription", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10037185", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10037201", "reaction_10087900", "reaction_10088482", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-109582": { "id": "pathway_10092842", "reactome": "R-BTA-109582", "name": "Hemostasis", "reactions": [ "reaction_10037913", "reaction_10038129", "reaction_10038149", "reaction_10091600", "reaction_10090718", "reaction_10049300", "reaction_10047475", "reaction_10053213", "reaction_10038303", "reaction_10047893", "reaction_10048587", "reaction_10043323", "reaction_10038329", "reaction_10050994", "reaction_10055920", "reaction_10076743", "reaction_10037927", "reaction_10043375", "reaction_10037353", "reaction_10056002", "reaction_10038201", "reaction_10048635", "reaction_10037852", "reaction_10049071", "reaction_10091701", "reaction_10055831", "reaction_10091546", "reaction_10037588", "reaction_10055833", "reaction_10071906", "reaction_10037895", "reaction_10038307", "reaction_10055649", "reaction_10043363", "reaction_10071946", "reaction_10051002", "reaction_10043355", "reaction_10037923", "reaction_10037948", "reaction_10044030", "reaction_10038288", "reaction_10049279", "reaction_10055823", "reaction_10085323", "reaction_10065227", "reaction_10037557", "reaction_10037800", "reaction_10037937", "reaction_10037899", "reaction_10037915", "reaction_10049039", "reaction_10047212", "reaction_10055870", "reaction_10055647", "reaction_10049506", "reaction_10037433", "reaction_10055827", "reaction_10047857", "reaction_10038213", "reaction_10055515", "reaction_10092299", "reaction_10048580", "reaction_10048543", "reaction_10050870", "reaction_10044043", "reaction_10038285", "reaction_10037845", "reaction_10048504", "reaction_10048182", "reaction_10055995", "reaction_10055933", "reaction_10044039", "reaction_10047930", "reaction_10038270", "reaction_10038290", "reaction_10038263", "reaction_10037517", "reaction_10043347", "reaction_10055829", "reaction_10037887", "reaction_10066263", "reaction_10047900", "reaction_10049283", "reaction_10044018", "reaction_10051062", "reaction_10037607", "reaction_10055645", "reaction_10038221", "reaction_10044034", "reaction_10048632", "reaction_10037950", "reaction_10037815", "reaction_10048660", "reaction_10038166", "reaction_10037580", "reaction_10055529", "reaction_10049364", "reaction_10049067", "reaction_10037906", "reaction_10050630", "reaction_10049290", "reaction_10090183", "reaction_10043335", "reaction_10090181", "reaction_10049014", "reaction_10038205", "reaction_10050948", "reaction_10047907", "reaction_10043397", "reaction_10049035", "reaction_10044024", "reaction_10049426", "reaction_10049395", "reaction_10047870", "reaction_10047880", "reaction_10047380", "reaction_10090185", "reaction_10045016", "reaction_10055847", "reaction_10091671", "reaction_10047985", "reaction_10047886", "reaction_10044020", "reaction_10043393", "reaction_10050924", "reaction_10085753", "reaction_10038292" ] }, "R-BTA-9006934": { "id": "pathway_10092646", "reactome": "R-BTA-9006934", "name": "Signaling by Receptor Tyrosine Kinases", "reactions": [ "reaction_10090994", "reaction_10072979", "reaction_10040286", "reaction_10073147", "reaction_10057327", "reaction_10040393", "reaction_10040769", "reaction_10071504", "reaction_10072993", "reaction_10041917", "reaction_10040229", "reaction_10040744", "reaction_10040451", "reaction_10040779", "reaction_10057139", "reaction_10041463", "reaction_10040462", "reaction_10075063", "reaction_10057862", "reaction_10039736", "reaction_10073077", "reaction_10073234", "reaction_10057188", "reaction_10044470", "reaction_10057329", "reaction_10040776", "reaction_10059156", "reaction_10043815", "reaction_10042826", "reaction_10039581", "reaction_10053082", "reaction_10057252", "reaction_10084849", "reaction_10090949", "reaction_10070676", "reaction_10039697", "reaction_10073021", "reaction_10073115", "reaction_10057318", "reaction_10056781", "reaction_10072999", "reaction_10087373", "reaction_10086415", "reaction_10073102", "reaction_10073001", "reaction_10040447", "reaction_10073031", "reaction_10040277", "reaction_10090675", "reaction_10072957", "reaction_10091667", "reaction_10073184", "reaction_10040421", "reaction_10036598", "reaction_10090944", "reaction_10073119", "reaction_10040267", "reaction_10043488", "reaction_10072937", "reaction_10073201", "reaction_10040761", "reaction_10061492", "reaction_10057184", "reaction_10040331", "reaction_10075065", "reaction_10090722", "reaction_10057236", "reaction_10039272", "reaction_10072946", "reaction_10073326", "reaction_10040489", "reaction_10057191", "reaction_10072939", "reaction_10073108", "reaction_10040289", "reaction_10040258", "reaction_10057286", "reaction_10073106", "reaction_10073208", "reaction_10073113", "reaction_10041869", "reaction_10091751", "reaction_10039601", "reaction_10073225", "reaction_10040432", "reaction_10035536", "reaction_10039270", "reaction_10057314", "reaction_10071508", "reaction_10073122", "reaction_10040326", "reaction_10058478", "reaction_10040696", "reaction_10070651", "reaction_10070645", "reaction_10057262", "reaction_10073133", "reaction_10057735", "reaction_10057700", "reaction_10057695", "reaction_10057854", "reaction_10073011", "reaction_10039690", "reaction_10073044", "reaction_10058474", "reaction_10065227", "reaction_10073228", "reaction_10072909", "reaction_10044465", "reaction_10090954", "reaction_10057704", "reaction_10074879", "reaction_10087370", "reaction_10080870", "reaction_10040773", "reaction_10073328", "reaction_10083477", "reaction_10084080", "reaction_10061458", "reaction_10040458", "reaction_10041950", "reaction_10083483", "reaction_10073071", "reaction_10040453", "reaction_10043832", "reaction_10040369", "reaction_10057337", "reaction_10057857", "reaction_10073041", "reaction_10040782", "reaction_10041453", "reaction_10040495", "reaction_10044472", "reaction_10057740", "reaction_10040317", "reaction_10035527", "reaction_10041649", "reaction_10073222", "reaction_10072929", "reaction_10091705", "reaction_10040788", "reaction_10073192", "reaction_10073240", "reaction_10073145", "reaction_10057151", "reaction_10057872", "reaction_10057175", "reaction_10070628", "reaction_10046660", "reaction_10072976", "reaction_10041851", "reaction_10071506", "reaction_10046677", "reaction_10090727", "reaction_10073199", "reaction_10077601", "reaction_10046666", "reaction_10090971", "reaction_10070594", "reaction_10040386", "reaction_10073004", "reaction_10057177", "reaction_10077605", "reaction_10040303", "reaction_10038450", "reaction_10073175", "reaction_10072944", "reaction_10040753", "reaction_10073037", "reaction_10057744", "reaction_10040794", "reaction_10072933", "reaction_10083933", "reaction_10036607", "reaction_10084067", "reaction_10073237", "reaction_10057867", "reaction_10073246", "reaction_10040720", "reaction_10058480", "reaction_10039592", "reaction_10073231", "reaction_10073244", "reaction_10073177", "reaction_10057719", "reaction_10075097", "reaction_10073028", "reaction_10073136", "reaction_10073159", "reaction_10072927", "reaction_10057323", "reaction_10040310", "reaction_10073215", "reaction_10057692", "reaction_10057845", "reaction_10073014", "reaction_10043315", "reaction_10073129", "reaction_10073083", "reaction_10073090", "reaction_10070624", "reaction_10073019", "reaction_10072935", "reaction_10040299", "reaction_10061480", "reaction_10057850", "reaction_10040323", "reaction_10090666", "reaction_10072920", "reaction_10070589", "reaction_10040785", "reaction_10073127", "reaction_10073087", "reaction_10040570", "reaction_10036570", "reaction_10069535", "reaction_10057284", "reaction_10073242", "reaction_10087367", "reaction_10041657", "reaction_10073166", "reaction_10040684", "reaction_10083935", "reaction_10070615", "reaction_10040328", "reaction_10057707", "reaction_10070596", "reaction_10057264", "reaction_10057298", "reaction_10091689", "reaction_10040704", "reaction_10057742", "reaction_10035507", "reaction_10073152", "reaction_10073140", "reaction_10057712", "reaction_10070657", "reaction_10072931", "reaction_10040460", "reaction_10036590", "reaction_10057166", "reaction_10087376", "reaction_10040254", "reaction_10061469", "reaction_10073097", "reaction_10057272", "reaction_10072913", "reaction_10040791", "reaction_10073182", "reaction_10073156", "reaction_10073047", "reaction_10040860", "reaction_10039711", "reaction_10036616", "reaction_10057302" ] }, "R-BTA-211945": { "id": "pathway_10092560", "reactome": "R-BTA-211945", "name": "Phase I - Functionalization of compounds", "reactions": [ "reaction_10044477", "reaction_10044533", "reaction_10077496", "reaction_10086550", "reaction_10041177", "reaction_10075404", "reaction_10076375", "reaction_10043971", "reaction_10041412", "reaction_10044235", "reaction_10041386", "reaction_10035958", "reaction_10044182", "reaction_10044255", "reaction_10037751", "reaction_10086543", "reaction_10034231", "reaction_10034206", "reaction_10044242", "reaction_10044280", "reaction_10041415", "reaction_10044250", "reaction_10044223", "reaction_10044275", "reaction_10044204", "reaction_10035977", "reaction_10077734", "reaction_10041195", "reaction_10035878", "reaction_10044216", "reaction_10076884", "reaction_10044524", "reaction_10044225", "reaction_10044265", "reaction_10035911", "reaction_10037748", "reaction_10041397", "reaction_10044167", "reaction_10038000", "reaction_10071909", "reaction_10044247", "reaction_10034175", "reaction_10086557", "reaction_10034215", "reaction_10044195", "reaction_10077751", "reaction_10035865", "reaction_10044218", "reaction_10043964", "reaction_10041393", "reaction_10041193", "reaction_10044151", "reaction_10044270", "reaction_10076144", "reaction_10041277", "reaction_10086469", "reaction_10044211", "reaction_10044480", "reaction_10044158", "reaction_10076475", "reaction_10041217", "reaction_10041206", "reaction_10076856", "reaction_10044260", "reaction_10044232", "reaction_10044293", "reaction_10076863", "reaction_10035861", "reaction_10050160", "reaction_10041500" ] }, "R-BTA-211859": { "id": "pathway_10092562", "reactome": "R-BTA-211859", "name": "Biological oxidations", "reactions": [ "reaction_10071712", "reaction_10039887", "reaction_10038318", "reaction_10071722", "reaction_10038338", "reaction_10044255", "reaction_10035863", "reaction_10040136", "reaction_10044250", "reaction_10076900", "reaction_10038060", "reaction_10035977", "reaction_10076898", "reaction_10040030", "reaction_10071763", "reaction_10035911", "reaction_10071909", "reaction_10040115", "reaction_10034215", "reaction_10038380", "reaction_10087515", "reaction_10038340", "reaction_10039921", "reaction_10038354", "reaction_10086469", "reaction_10041277", "reaction_10044211", "reaction_10044480", "reaction_10038336", "reaction_10040021", "reaction_10044232", "reaction_10076903", "reaction_10041500", "reaction_10071754", "reaction_10044477", "reaction_10071729", "reaction_10038371", "reaction_10041177", "reaction_10071717", "reaction_10043971", "reaction_10077658", "reaction_10039874", "reaction_10044235", "reaction_10041386", "reaction_10044182", "reaction_10086543", "reaction_10038231", "reaction_10034206", "reaction_10044223", "reaction_10041415", "reaction_10044225", "reaction_10038000", "reaction_10039865", "reaction_10039918", "reaction_10040152", "reaction_10044270", "reaction_10041193", "reaction_10067425", "reaction_10041206", "reaction_10076856", "reaction_10044293", "reaction_10050160", "reaction_10040185", "reaction_10077496", "reaction_10075404", "reaction_10041412", "reaction_10037751", "reaction_10034231", "reaction_10040129", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10037748", "reaction_10076884", "reaction_10044265", "reaction_10040157", "reaction_10041397", "reaction_10044167", "reaction_10044247", "reaction_10034175", "reaction_10040112", "reaction_10071924", "reaction_10038382", "reaction_10076799", "reaction_10086557", "reaction_10038238", "reaction_10044195", "reaction_10039930", "reaction_10040107", "reaction_10041393", "reaction_10040098", "reaction_10071715", "reaction_10088617", "reaction_10076475", "reaction_10044158", "reaction_10040117", "reaction_10039916", "reaction_10076785", "reaction_10035861", "reaction_10076863", "reaction_10076133", "reaction_10038316", "reaction_10041195", "reaction_10040147", "reaction_10044533", "reaction_10086550", "reaction_10076375", "reaction_10035958", "reaction_10044242", "reaction_10044204", "reaction_10044275", "reaction_10035878", "reaction_10040131", "reaction_10044216", "reaction_10040122", "reaction_10044524", "reaction_10057079", "reaction_10077751", "reaction_10040120", "reaction_10035865", "reaction_10038320", "reaction_10044218", "reaction_10043964", "reaction_10044151", "reaction_10076144", "reaction_10051570", "reaction_10071727", "reaction_10041217", "reaction_10044260", "reaction_10039923", "reaction_10088580" ] }, "R-BTA-168256": { "id": "pathway_10093006", "reactome": "R-BTA-168256", "name": "Immune System", "reactions": [ "reaction_10051936", "reaction_10065009", "reaction_10043302", "reaction_10050196", "reaction_10066551", "reaction_10056268", "reaction_10089466", "reaction_10054791", "reaction_10072364", "reaction_10065051", "reaction_10092165", "reaction_10063374", "reaction_10077921", "reaction_10066141", "reaction_10077790", "reaction_10051966", "reaction_10072045", "reaction_10065413", "reaction_10073690", "reaction_10051786", "reaction_10089329", "reaction_10092257", "reaction_10092043", "reaction_10039217", "reaction_10061502", "reaction_10077843", "reaction_10080842", "reaction_10089480", "reaction_10086405", "reaction_10052294", "reaction_10043488", "reaction_10052337", "reaction_10077874", "reaction_10055491", "reaction_10056084", "reaction_10087787", "reaction_10089341", "reaction_10081385", "reaction_10087671", "reaction_10082967", "reaction_10060783", "reaction_10055958", "reaction_10089321", "reaction_10089516", "reaction_10084658", "reaction_10089333", "reaction_10073757", "reaction_10089536", "reaction_10055453", "reaction_10050254", "reaction_10052343", "reaction_10072383", "reaction_10089523", "reaction_10087774", "reaction_10089530", "reaction_10046903", "reaction_10065011", "reaction_10058492", "reaction_10081404", "reaction_10091723", "reaction_10074312", "reaction_10089591", "reaction_10056178", "reaction_10084683", "reaction_10056912", "reaction_10089311", "reaction_10055955", "reaction_10056199", "reaction_10081943", "reaction_10091743", "reaction_10050256", "reaction_10067225", "reaction_10084636", "reaction_10089453", "reaction_10089689", "reaction_10054649", "reaction_10055971", "reaction_10079391", "reaction_10065642", "reaction_10074993", "reaction_10060773", "reaction_10056914", "reaction_10081905", "reaction_10089349", "reaction_10056132", "reaction_10053122", "reaction_10072053", "reaction_10051771", "reaction_10089511", "reaction_10043193", "reaction_10077926", "reaction_10065491", "reaction_10052229", "reaction_10082008", "reaction_10050623", "reaction_10056315", "reaction_10089542", "reaction_10066880", "reaction_10056335", "reaction_10053095", "reaction_10050428", "reaction_10060412", "reaction_10056283", "reaction_10089736", "reaction_10089269", "reaction_10084322", "reaction_10089597", "reaction_10089331", "reaction_10067216", "reaction_10072022", "reaction_10084686", "reaction_10089812", "reaction_10066168", "reaction_10077870", "reaction_10050619", "reaction_10055819", "reaction_10066532", "reaction_10063376", "reaction_10078759", "reaction_10051696", "reaction_10066536", "reaction_10046932", "reaction_10055448", "reaction_10067223", "reaction_10050231", "reaction_10042826", "reaction_10065402", "reaction_10046909", "reaction_10063353", "reaction_10042129", "reaction_10090919", "reaction_10090400", "reaction_10090844", "reaction_10083100", "reaction_10087697", "reaction_10056185", "reaction_10060732", "reaction_10067233", "reaction_10072057", "reaction_10064219", "reaction_10082012", "reaction_10052217", "reaction_10051196", "reaction_10052325", "reaction_10057004", "reaction_10089267", "reaction_10039465", "reaction_10089625", "reaction_10079199", "reaction_10056910", "reaction_10092126", "reaction_10051737", "reaction_10089431", "reaction_10061657", "reaction_10056172", "reaction_10087780", "reaction_10075923", "reaction_10066065", "reaction_10090837", "reaction_10091739", "reaction_10090031", "reaction_10056287", "reaction_10052210", "reaction_10057834", "reaction_10080063", "reaction_10089819", "reaction_10091747", "reaction_10077924", "reaction_10041950", "reaction_10066127", "reaction_10054779", "reaction_10039778", "reaction_10072002", "reaction_10089538", "reaction_10066059", "reaction_10064068", "reaction_10081406", "reaction_10084867", "reaction_10051818", "reaction_10052735", "reaction_10066052", "reaction_10089446", "reaction_10066147", "reaction_10089444", "reaction_10090916", "reaction_10092195", "reaction_10043867", "reaction_10074899", "reaction_10055431", "reaction_10077723", "reaction_10056539", "reaction_10081432", "reaction_10055817", "reaction_10092183", "reaction_10089621", "reaction_10084020", "reaction_10092151", "reaction_10072006", "reaction_10041863", "reaction_10092147", "reaction_10050028", "reaction_10076165", "reaction_10056835", "reaction_10050527", "reaction_10087766", "reaction_10047907", "reaction_10083522", "reaction_10082183", "reaction_10051792", "reaction_10056082", "reaction_10084672", "reaction_10050420", "reaction_10087650", "reaction_10042786", "reaction_10052327", "reaction_10065388", "reaction_10076237", "reaction_10089427", "reaction_10074306", "reaction_10092141", "reaction_10043241", "reaction_10052240", "reaction_10092137", "reaction_10046834", "reaction_10056102", "reaction_10049721", "reaction_10087797", "reaction_10046951", "reaction_10077764", "reaction_10084865", "reaction_10089363", "reaction_10081085", "reaction_10056297", "reaction_10077904", "reaction_10072395", "reaction_10056127", "reaction_10052321", "reaction_10066144", "reaction_10074266", "reaction_10066102", "reaction_10055821", "reaction_10072032", "reaction_10039560", "reaction_10072015", "reaction_10054494", "reaction_10080844", "reaction_10043300", "reaction_10089691", "reaction_10072388", "reaction_10056088", "reaction_10070719", "reaction_10052196", "reaction_10050011", "reaction_10080435", "reaction_10042253", "reaction_10081397", "reaction_10087783", "reaction_10087763", "reaction_10056416", "reaction_10051774", "reaction_10043659", "reaction_10049970", "reaction_10065055", "reaction_10083537", "reaction_10087823", "reaction_10043274", "reaction_10089843", "reaction_10063972", "reaction_10047530", "reaction_10077945", "reaction_10053058", "reaction_10079949", "reaction_10077422", "reaction_10071975", "reaction_10074340", "reaction_10091757", "reaction_10065227", "reaction_10042623", "reaction_10087795", "reaction_10089251", "reaction_10046787", "reaction_10049946", "reaction_10051962", "reaction_10091731", "reaction_10070906", "reaction_10074901", "reaction_10072374", "reaction_10066180", "reaction_10066151", "reaction_10056130", "reaction_10081559", "reaction_10043304", "reaction_10067229", "reaction_10090027", "reaction_10072061", "reaction_10043270", "reaction_10058486", "reaction_10078929", "reaction_10077633", "reaction_10055451", "reaction_10043244", "reaction_10074318", "reaction_10056982", "reaction_10080831", "reaction_10066172", "reaction_10080719", "reaction_10065019", "reaction_10052147", "reaction_10092318", "reaction_10052347", "reaction_10092133", "reaction_10077424", "reaction_10087663", "reaction_10092033", "reaction_10050208", "reaction_10052471", "reaction_10060730", "reaction_10060759", "reaction_10039508", "reaction_10077919", "reaction_10046822", "reaction_10052233", "reaction_10056090", "reaction_10052189", "reaction_10052466", "reaction_10045016", "reaction_10058456", "reaction_10089595", "reaction_10066608", "reaction_10081506", "reaction_10087726", "reaction_10092040", "reaction_10057836", "reaction_10064277", "reaction_10050024", "reaction_10088519", "reaction_10075009", "reaction_10051194", "reaction_10073699", "reaction_10056201", "reaction_10052213", "reaction_10051762", "reaction_10052254", "reaction_10056531", "reaction_10053134", "reaction_10089506", "reaction_10053213", "reaction_10056205", "reaction_10089442", "reaction_10046807", "reaction_10066094", "reaction_10046888", "reaction_10083967", "reaction_10081265", "reaction_10081510", "reaction_10051836", "reaction_10043262", "reaction_10043212", "reaction_10065407", "reaction_10056805", "reaction_10053048", "reaction_10074280", "reaction_10074314", "reaction_10072011", "reaction_10092108", "reaction_10055783", "reaction_10089291", "reaction_10083106", "reaction_10040197", "reaction_10087789", "reaction_10085369", "reaction_10089615", "reaction_10092139", "reaction_10056170", "reaction_10054678", "reaction_10056110", "reaction_10071982", "reaction_10089540", "reaction_10043219", "reaction_10087732", "reaction_10050218", "reaction_10051095", "reaction_10052067", "reaction_10083959", "reaction_10043182", "reaction_10065517", "reaction_10066082", "reaction_10055444", "reaction_10060785", "reaction_10089253", "reaction_10065894", "reaction_10084706", "reaction_10050192", "reaction_10043298", "reaction_10056188", "reaction_10066238", "reaction_10092173", "reaction_10077455", "reaction_10081410", "reaction_10066080", "reaction_10056239", "reaction_10089455", "reaction_10046959", "reaction_10064214", "reaction_10079653", "reaction_10057823", "reaction_10056289", "reaction_10064221", "reaction_10056194", "reaction_10055946", "reaction_10066120", "reaction_10055967", "reaction_10056176", "reaction_10061174", "reaction_10074320", "reaction_10052236", "reaction_10056903", "reaction_10060694", "reaction_10076963", "reaction_10082977", "reaction_10051780", "reaction_10084305", "reaction_10065021", "reaction_10051748", "reaction_10073765", "reaction_10082004", "reaction_10050054", "reaction_10090019", "reaction_10087338", "reaction_10043252", "reaction_10087807", "reaction_10058388", "reaction_10091725", "reaction_10055460", "reaction_10056207", "reaction_10046907", "reaction_10046943", "reaction_10066559", "reaction_10039782", "reaction_10056123", "reaction_10052323", "reaction_10047519", "reaction_10039481", "reaction_10089703", "reaction_10054736", "reaction_10091817", "reaction_10054866", "reaction_10049928", "reaction_10073708", "reaction_10071948", "reaction_10067231", "reaction_10089696", "reaction_10052159", "reaction_10072030", "reaction_10043225", "reaction_10087601", "reaction_10063368", "reaction_10092143", "reaction_10051949", "reaction_10092159", "reaction_10074308", "reaction_10088498", "reaction_10074316", "reaction_10056168", "reaction_10087793", "reaction_10074310", "reaction_10084401", "reaction_10049983", "reaction_10042635", "reaction_10054524", "reaction_10064118", "reaction_10053046", "reaction_10047536", "reaction_10085017", "reaction_10051954", "reaction_10072392", "reaction_10046811", "reaction_10052302" ] }, "R-BTA-500792": { "id": "pathway_10092986", "reactome": "R-BTA-500792", "name": "GPCR ligand binding", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10048326", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10086575", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048248", "reaction_10047396", "reaction_10048208", "reaction_10045072", "reaction_10049617", "reaction_10048270", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10051907", "reaction_10045138", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048304", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10067348", "reaction_10053333", "reaction_10046733", "reaction_10049643", "reaction_10047332", "reaction_10078536", "reaction_10038918", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10086565", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10049681", "reaction_10067358", "reaction_10048282", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-74160": { "id": "pathway_10092440", "reactome": "R-BTA-74160", "name": "Gene expression (Transcription)", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10048682", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10071065", "reaction_10037185", "reaction_10048720", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10037207", "reaction_10072557", "reaction_10088546", "reaction_10086241", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10044390", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10081561", "reaction_10080457", "reaction_10035301", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10035854", "reaction_10037205", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10044381", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10037189", "reaction_10081595", "reaction_10066712", "reaction_10038904", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10036080", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10035254", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10037203", "reaction_10086587", "reaction_10070702", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10036915", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10037187", "reaction_10080738", "reaction_10070700", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10044333", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10044361", "reaction_10086502", "reaction_10091096", "reaction_10087862", "reaction_10046681", "reaction_10081499", "reaction_10048717", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10037201" ] }, "R-BTA-382551": { "id": "pathway_10092732", "reactome": "R-BTA-382551", "name": "Transport of small molecules", "reactions": [ "reaction_10052907", "reaction_10048740", "reaction_10049402", "reaction_10049333", "reaction_10051307", "reaction_10049090", "reaction_10048478", "reaction_10049635", "reaction_10066227", "reaction_10049371", "reaction_10086004", "reaction_10047893", "reaction_10053143", "reaction_10085994", "reaction_10049358", "reaction_10049871", "reaction_10051589", "reaction_10048567", "reaction_10048965", "reaction_10052916", "reaction_10049319", "reaction_10066034", "reaction_10045494", "reaction_10081968", "reaction_10045419", "reaction_10048526", "reaction_10049613", "reaction_10057062", "reaction_10066289", "reaction_10049080", "reaction_10049241", "reaction_10065991", "reaction_10091759", "reaction_10086343", "reaction_10044978", "reaction_10051892", "reaction_10076099", "reaction_10074474", "reaction_10087646", "reaction_10085907", "reaction_10052888", "reaction_10076179", "reaction_10051314", "reaction_10049173", "reaction_10036283", "reaction_10074493", "reaction_10071462", "reaction_10045501", "reaction_10049464", "reaction_10057070", "reaction_10052923", "reaction_10045473", "reaction_10051136", "reaction_10049583", "reaction_10039874", "reaction_10048761", "reaction_10066270", "reaction_10048795", "reaction_10086002", "reaction_10086026", "reaction_10066199", "reaction_10051269", "reaction_10091250", "reaction_10049433", "reaction_10044964", "reaction_10070728", "reaction_10059181", "reaction_10058792", "reaction_10051145", "reaction_10083113", "reaction_10049060", "reaction_10036290", "reaction_10089024", "reaction_10049592", "reaction_10073838", "reaction_10048747", "reaction_10067332", "reaction_10045480", "reaction_10049606", "reaction_10049392", "reaction_10049078", "reaction_10066277", "reaction_10052909", "reaction_10070906", "reaction_10036276", "reaction_10088912", "reaction_10045050", "reaction_10051286", "reaction_10051843", "reaction_10049262", "reaction_10051547", "reaction_10074360", "reaction_10051580", "reaction_10070991", "reaction_10036274", "reaction_10048550", "reaction_10048533", "reaction_10091542", "reaction_10071254", "reaction_10087365", "reaction_10070743", "reaction_10092050", "reaction_10044962", "reaction_10072522", "reaction_10051141", "reaction_10049046", "reaction_10051577", "reaction_10089038", "reaction_10070735", "reaction_10048504", "reaction_10066004", "reaction_10057007", "reaction_10049440", "reaction_10044547", "reaction_10048618", "reaction_10048601", "reaction_10070928", "reaction_10051325", "reaction_10045487", "reaction_10049326", "reaction_10051899", "reaction_10048727", "reaction_10053258", "reaction_10051143", "reaction_10071490", "reaction_10049083", "reaction_10058790", "reaction_10048768", "reaction_10058216", "reaction_10058469", "reaction_10049378", "reaction_10040636", "reaction_10049869", "reaction_10044941", "reaction_10086557", "reaction_10053180", "reaction_10048491", "reaction_10084767", "reaction_10088982", "reaction_10051276", "reaction_10047900", "reaction_10074686", "reaction_10071469", "reaction_10044934", "reaction_10089029", "reaction_10051148", "reaction_10076091", "reaction_10065965", "reaction_10089048", "reaction_10049385", "reaction_10051545", "reaction_10066206", "reaction_10044955", "reaction_10091583", "reaction_10049243", "reaction_10074486", "reaction_10066232", "reaction_10085384", "reaction_10052925", "reaction_10067346", "reaction_10051587", "reaction_10048754", "reaction_10052866", "reaction_10066282", "reaction_10057832", "reaction_10048594", "reaction_10085896", "reaction_10048802", "reaction_10052914", "reaction_10036297", "reaction_10071001", "reaction_10052901", "reaction_10051879", "reaction_10076083", "reaction_10046707", "reaction_10051554", "reaction_10038660", "reaction_10049170", "reaction_10076172", "reaction_10048787", "reaction_10046698", "reaction_10051150", "reaction_10077487", "reaction_10049053", "reaction_10071280", "reaction_10048821", "reaction_10089060", "reaction_10049628", "reaction_10049447", "reaction_10044666", "reaction_10089058", "reaction_10071003", "reaction_10047483", "reaction_10049271", "reaction_10049253", "reaction_10066021", "reaction_10052911", "reaction_10071476", "reaction_10089062", "reaction_10051866", "reaction_10053210", "reaction_10044971", "reaction_10060218", "reaction_10048804", "reaction_10051570", "reaction_10051305", "reaction_10049599", "reaction_10088905", "reaction_10084509", "reaction_10084300", "reaction_10051283", "reaction_10044985", "reaction_10048958", "reaction_10077489", "reaction_10044948", "reaction_10085967" ] }, "R-BTA-597592": { "id": "pathway_10092946", "reactome": "R-BTA-597592", "name": "Post-translational protein modification", "reactions": [ "reaction_10088688", "reaction_10053317", "reaction_10077710", "reaction_10054550", "reaction_10075808", "reaction_10075550", "reaction_10087852", "reaction_10049797", "reaction_10069359", "reaction_10053324", "reaction_10081490", "reaction_10049811", "reaction_10075989", "reaction_10076696", "reaction_10038416", "reaction_10077371", "reaction_10052665", "reaction_10076001", "reaction_10043698", "reaction_10088807", "reaction_10069329", "reaction_10069498", "reaction_10077883", "reaction_10082026", "reaction_10086710", "reaction_10075397", "reaction_10082038", "reaction_10083380", "reaction_10087883", "reaction_10053331", "reaction_10077339", "reaction_10054575", "reaction_10087885", "reaction_10075561", "reaction_10076698", "reaction_10052461", "reaction_10077897", "reaction_10043649", "reaction_10077363", "reaction_10056058", "reaction_10085345", "reaction_10071579", "reaction_10084931", "reaction_10069320", "reaction_10043717", "reaction_10049860", "reaction_10076584", "reaction_10052716", "reaction_10087993", "reaction_10077034", "reaction_10077800", "reaction_10049804", "reaction_10060109", "reaction_10076736", "reaction_10053337", "reaction_10052496", "reaction_10087825", "reaction_10038438", "reaction_10069373", "reaction_10077807", "reaction_10077717", "reaction_10054766", "reaction_10052521", "reaction_10083377", "reaction_10053339", "reaction_10075952", "reaction_10077826", "reaction_10076415", "reaction_10091630", "reaction_10077349", "reaction_10076112", "reaction_10049851", "reaction_10077406", "reaction_10049844", "reaction_10084117", "reaction_10076775", "reaction_10076590", "reaction_10076708", "reaction_10069371", "reaction_10077823", "reaction_10086319", "reaction_10061538", "reaction_10075942", "reaction_10038457", "reaction_10082941", "reaction_10052690", "reaction_10069357", "reaction_10049818", "reaction_10054418", "reaction_10085101", "reaction_10054438", "reaction_10076706", "reaction_10086286", "reaction_10066409", "reaction_10084373", "reaction_10076119", "reaction_10056074", "reaction_10076773", "reaction_10077331", "reaction_10082045", "reaction_10049831", "reaction_10038408", "reaction_10068095", "reaction_10049778", "reaction_10076778", "reaction_10050153", "reaction_10077816", "reaction_10077317", "reaction_10069382", "reaction_10077379", "reaction_10076610", "reaction_10054467", "reaction_10052606", "reaction_10054722", "reaction_10054474", "reaction_10086303", "reaction_10077393", "reaction_10049789", "reaction_10084122", "reaction_10071566", "reaction_10069346", "reaction_10051554", "reaction_10075970", "reaction_10049867", "reaction_10076635", "reaction_10077292", "reaction_10069368", "reaction_10076586", "reaction_10040933", "reaction_10075891", "reaction_10056061", "reaction_10084008", "reaction_10084113", "reaction_10052546", "reaction_10086702", "reaction_10066372", "reaction_10077070", "reaction_10049858", "reaction_10088734", "reaction_10077688", "reaction_10088787", "reaction_10075902", "reaction_10077744", "reaction_10066380", "reaction_10054773", "reaction_10075374", "reaction_10076422", "reaction_10054411", "reaction_10088473", "reaction_10085250", "reaction_10054431", "reaction_10081497", "reaction_10069348", "reaction_10038464", "reaction_10070145", "reaction_10075984", "reaction_10048958", "reaction_10087848" ] }, "R-BTA-556833": { "id": "pathway_10092528", "reactome": "R-BTA-556833", "name": "Metabolism of lipids", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10082880", "reaction_10041363", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10041359", "reaction_10071388", "reaction_10083575", "reaction_10060569", "reaction_10082934", "reaction_10058998", "reaction_10059977", "reaction_10036029", "reaction_10063444", "reaction_10060302", "reaction_10044657", "reaction_10063560", "reaction_10071344", "reaction_10041477", "reaction_10060448", "reaction_10064442", "reaction_10041500", "reaction_10047807", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10082152", "reaction_10085784", "reaction_10047001", "reaction_10076792", "reaction_10041357", "reaction_10047058", "reaction_10036021", "reaction_10064465", "reaction_10041415", "reaction_10033896", "reaction_10041310", "reaction_10059006", "reaction_10041290", "reaction_10064452", "reaction_10040895", "reaction_10041327", "reaction_10086403", "reaction_10085843", "reaction_10084480", "reaction_10041664", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10064546", "reaction_10082058", "reaction_10088928", "reaction_10085316", "reaction_10035417", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10041349", "reaction_10064474", "reaction_10060553", "reaction_10037748", "reaction_10090390", "reaction_10036042", "reaction_10041493", "reaction_10046989", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10041204", "reaction_10085775", "reaction_10047056", "reaction_10041301", "reaction_10041299", "reaction_10048882", "reaction_10041195", "reaction_10090468", "reaction_10076806", "reaction_10090394", "reaction_10041208", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10085291", "reaction_10058812", "reaction_10084424", "reaction_10040933", "reaction_10041424", "reaction_10064503", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10047065", "reaction_10059016", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10075631", "reaction_10041317", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10040922", "reaction_10060461", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10064516", "reaction_10058894", "reaction_10036220", "reaction_10060041", "reaction_10060614", "reaction_10084694", "reaction_10046992", "reaction_10041323", "reaction_10035786", "reaction_10086336", "reaction_10060600", "reaction_10049004", "reaction_10085798", "reaction_10060590", "reaction_10041437", "reaction_10041671", "reaction_10058916", "reaction_10041277", "reaction_10076281", "reaction_10060429", "reaction_10083369", "reaction_10059035", "reaction_10090379", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10049182", "reaction_10046984", "reaction_10090440", "reaction_10060572", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10040913", "reaction_10049163", "reaction_10048986", "reaction_10058908", "reaction_10041226", "reaction_10041341", "reaction_10035372", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10090460", "reaction_10041111", "reaction_10041170", "reaction_10063420", "reaction_10060476", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10047042", "reaction_10064479", "reaction_10059114", "reaction_10058892", "reaction_10049154", "reaction_10058945", "reaction_10041716", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10059141", "reaction_10060468", "reaction_10044599", "reaction_10041484", "reaction_10059991", "reaction_10054592", "reaction_10092062", "reaction_10035795", "reaction_10041397", "reaction_10088026", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10036664", "reaction_10083800", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10041367", "reaction_10059094", "reaction_10064445", "reaction_10041369", "reaction_10058943", "reaction_10033889", "reaction_10080887", "reaction_10059026", "reaction_10041365", "reaction_10059853", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10064534", "reaction_10040892", "reaction_10092065", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10090382", "reaction_10051261", "reaction_10041353", "reaction_10063456", "reaction_10059851", "reaction_10077004", "reaction_10051676", "reaction_10035812", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10058993", "reaction_10083577", "reaction_10036038", "reaction_10058913", "reaction_10085808", "reaction_10063430", "reaction_10063442", "reaction_10059984", "reaction_10059856", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10041319", "reaction_10041179", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10083211", "reaction_10064491", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10041377", "reaction_10065225", "reaction_10042961", "reaction_10041172", "reaction_10041486", "reaction_10058834", "reaction_10043885", "reaction_10058874", "reaction_10041386", "reaction_10059858", "reaction_10040881", "reaction_10060109", "reaction_10033912", "reaction_10058896", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10041193", "reaction_10090498", "reaction_10090510", "reaction_10048978", "reaction_10060498", "reaction_10041293", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10074353", "reaction_10090384", "reaction_10085788", "reaction_10058975", "reaction_10059847", "reaction_10041412", "reaction_10083389", "reaction_10063564", "reaction_10085780", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10090489", "reaction_10059000", "reaction_10064578", "reaction_10059951", "reaction_10058910", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10060556", "reaction_10063413", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10086064", "reaction_10063437", "reaction_10036012", "reaction_10090464", "reaction_10088926", "reaction_10060550", "reaction_10041197", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10064581", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10090474", "reaction_10043984", "reaction_10063448", "reaction_10060021", "reaction_10077777", "reaction_10041297", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10058880", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10083547", "reaction_10041284", "reaction_10060597", "reaction_10090508", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10041321", "reaction_10090504", "reaction_10090392", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10084526", "reaction_10063428", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10044739", "reaction_10041721", "reaction_10060518", "reaction_10085340", "reaction_10043971", "reaction_10058809", "reaction_10085185", "reaction_10041347", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10041373", "reaction_10060535", "reaction_10063440", "reaction_10035838", "reaction_10059014", "reaction_10082136", "reaction_10043910", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10077835", "reaction_10047044", "reaction_10065223", "reaction_10058923", "reaction_10049161", "reaction_10085024", "reaction_10041379", "reaction_10060012", "reaction_10090386", "reaction_10058877", "reaction_10083092", "reaction_10086248", "reaction_10059121", "reaction_10040924", "reaction_10041502", "reaction_10058980", "reaction_10047033", "reaction_10058990", "reaction_10085806", "reaction_10059021", "reaction_10060514", "reaction_10060611", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10048995", "reaction_10059860", "reaction_10059961", "reaction_10049116", "reaction_10060316", "reaction_10077001", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10088019", "reaction_10041335", "reaction_10064511", "reaction_10043964", "reaction_10082889", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10041217", "reaction_10059150", "reaction_10091936" ] }, "R-BTA-5357801": { "id": "pathway_10092622", "reactome": "R-BTA-5357801", "name": "Programmed Cell Death", "reactions": [ "reaction_10037731", "reaction_10044146", "reaction_10068030", "reaction_10037678", "reaction_10037706", "reaction_10044756", "reaction_10091191", "reaction_10044869", "reaction_10037723", "reaction_10074240", "reaction_10038007", "reaction_10091409", "reaction_10091186", "reaction_10070684", "reaction_10072346", "reaction_10051181", "reaction_10037739", "reaction_10043021", "reaction_10091783", "reaction_10037727", "reaction_10037985", "reaction_10037622", "reaction_10092356", "reaction_10044568", "reaction_10051175", "reaction_10037253", "reaction_10037702", "reaction_10037277", "reaction_10067891", "reaction_10091793", "reaction_10044680", "reaction_10071534", "reaction_10091808", "reaction_10090573", "reaction_10091810", "reaction_10037289", "reaction_10091429", "reaction_10070531", "reaction_10091415", "reaction_10044906", "reaction_10037641", "reaction_10092350", "reaction_10068042", "reaction_10037991", "reaction_10043039", "reaction_10037618", "reaction_10070534", "reaction_10044762", "reaction_10068046", "reaction_10044896", "reaction_10044927", "reaction_10035396", "reaction_10037293", "reaction_10091197", "reaction_10037630", "reaction_10091188", "reaction_10092358", "reaction_10043059", "reaction_10081905", "reaction_10037674", "reaction_10039520", "reaction_10070682", "reaction_10092341", "reaction_10070689", "reaction_10090575", "reaction_10037264", "reaction_10092352", "reaction_10091423", "reaction_10092354", "reaction_10091773", "reaction_10044116", "reaction_10091439", "reaction_10043049", "reaction_10091806", "reaction_10044995", "reaction_10074254", "reaction_10044578", "reaction_10081897", "reaction_10091779", "reaction_10044142", "reaction_10037237", "reaction_10091425", "reaction_10044923", "reaction_10044144", "reaction_10067895" ] }, "R-BTA-1430728": { "id": "pathway_10092458", "reactome": "R-BTA-1430728", "name": "Metabolism", "reactions": [ "reaction_10059066", "reaction_10082931", "reaction_10066450", "reaction_10080521", "reaction_10088624", "reaction_10060216", "reaction_10082880", "reaction_10036683", "reaction_10041363", "reaction_10066430", "reaction_10058871", "reaction_10085826", "reaction_10059849", "reaction_10062697", "reaction_10035363", "reaction_10090472", "reaction_10058983", "reaction_10065216", "reaction_10090172", "reaction_10041104", "reaction_10048910", "reaction_10077113", "reaction_10053352", "reaction_10090645", "reaction_10040136", "reaction_10041359", "reaction_10044250", "reaction_10071388", "reaction_10076900", "reaction_10083575", "reaction_10060569", "reaction_10036308", "reaction_10063807", "reaction_10082934", "reaction_10065378", "reaction_10058998", "reaction_10059977", "reaction_10038427", "reaction_10039254", "reaction_10036029", "reaction_10034224", "reaction_10041772", "reaction_10080515", "reaction_10050437", "reaction_10051185", "reaction_10063444", "reaction_10087515", "reaction_10039921", "reaction_10044657", "reaction_10060302", "reaction_10038354", "reaction_10063560", "reaction_10064353", "reaction_10052030", "reaction_10083876", "reaction_10061064", "reaction_10071344", "reaction_10044480", "reaction_10041477", "reaction_10060448", "reaction_10034998", "reaction_10064442", "reaction_10034962", "reaction_10041500", "reaction_10047807", "reaction_10036938", "reaction_10061395", "reaction_10076274", "reaction_10064346", "reaction_10039044", "reaction_10090374", "reaction_10060473", "reaction_10085697", "reaction_10033620", "reaction_10059018", "reaction_10059063", "reaction_10064521", "reaction_10041177", "reaction_10080765", "reaction_10082152", "reaction_10061612", "reaction_10085784", "reaction_10039874", "reaction_10047001", "reaction_10044235", "reaction_10076792", "reaction_10078710", "reaction_10041357", "reaction_10082078", "reaction_10043956", "reaction_10047058", "reaction_10036021", "reaction_10044223", "reaction_10041415", "reaction_10064465", "reaction_10089808", "reaction_10033896", "reaction_10086272", "reaction_10090851", "reaction_10041310", "reaction_10060250", "reaction_10041790", "reaction_10038000", "reaction_10080519", "reaction_10077864", "reaction_10059006", "reaction_10039918", "reaction_10041290", "reaction_10064452", "reaction_10042847", "reaction_10040895", "reaction_10033962", "reaction_10041327", "reaction_10061116", "reaction_10090620", "reaction_10086403", "reaction_10046642", "reaction_10086371", "reaction_10034041", "reaction_10085843", "reaction_10084480", "reaction_10066526", "reaction_10063603", "reaction_10077890", "reaction_10076856", "reaction_10044293", "reaction_10041664", "reaction_10050160", "reaction_10041885", "reaction_10033718", "reaction_10040185", "reaction_10071497", "reaction_10060537", "reaction_10090491", "reaction_10041753", "reaction_10034953", "reaction_10063520", "reaction_10060255", "reaction_10064546", "reaction_10083614", "reaction_10090703", "reaction_10082058", "reaction_10088666", "reaction_10088928", "reaction_10043948", "reaction_10091291", "reaction_10085316", "reaction_10035417", "reaction_10041838", "reaction_10059002", "reaction_10059130", "reaction_10063562", "reaction_10063803", "reaction_10089721", "reaction_10036025", "reaction_10041692", "reaction_10035829", "reaction_10060678", "reaction_10036207", "reaction_10041349", "reaction_10077458", "reaction_10064474", "reaction_10060825", "reaction_10033706", "reaction_10037748", "reaction_10076884", "reaction_10060553", "reaction_10090390", "reaction_10044265", "reaction_10060625", "reaction_10090647", "reaction_10033570", "reaction_10061061", "reaction_10060980", "reaction_10040157", "reaction_10040636", "reaction_10044247", "reaction_10036042", "reaction_10041493", "reaction_10038382", "reaction_10063805", "reaction_10033840", "reaction_10046989", "reaction_10044195", "reaction_10081935", "reaction_10052046", "reaction_10039930", "reaction_10063014", "reaction_10041210", "reaction_10044741", "reaction_10076382", "reaction_10081339", "reaction_10041204", "reaction_10085775", "reaction_10044158", "reaction_10076475", "reaction_10047056", "reaction_10060993", "reaction_10062463", "reaction_10083852", "reaction_10077124", "reaction_10041301", "reaction_10066502", "reaction_10039916", "reaction_10076785", "reaction_10041299", "reaction_10076133", "reaction_10048882", "reaction_10035345", "reaction_10041195", "reaction_10090468", "reaction_10054375", "reaction_10041975", "reaction_10083204", "reaction_10044844", "reaction_10060361", "reaction_10068752", "reaction_10072898", "reaction_10033757", "reaction_10038895", "reaction_10035464", "reaction_10060228", "reaction_10082068", "reaction_10076806", "reaction_10090394", "reaction_10033770", "reaction_10091727", "reaction_10041208", "reaction_10076485", "reaction_10058841", "reaction_10090466", "reaction_10060483", "reaction_10060671", "reaction_10085291", "reaction_10065437", "reaction_10058812", "reaction_10044242", "reaction_10085362", "reaction_10049170", "reaction_10084424", "reaction_10089959", "reaction_10033594", "reaction_10036909", "reaction_10040933", "reaction_10041424", "reaction_10035878", "reaction_10058755", "reaction_10064503", "reaction_10040131", "reaction_10076441", "reaction_10063450", "reaction_10064531", "reaction_10060595", "reaction_10059101", "reaction_10033944", "reaction_10033690", "reaction_10041719", "reaction_10060574", "reaction_10041269", "reaction_10049189", "reaction_10060558", "reaction_10090396", "reaction_10036256", "reaction_10047065", "reaction_10067648", "reaction_10047019", "reaction_10059016", "reaction_10046630", "reaction_10035865", "reaction_10062655", "reaction_10060983", "reaction_10076254", "reaction_10090377", "reaction_10076833", "reaction_10044151", "reaction_10051165", "reaction_10075631", "reaction_10041317", "reaction_10067644", "reaction_10063454", "reaction_10041361", "reaction_10035374", "reaction_10035011", "reaction_10039923", "reaction_10040922", "reaction_10060461", "reaction_10089728", "reaction_10088580", "reaction_10090013", "reaction_10048917", "reaction_10059073", "reaction_10076824", "reaction_10076151", "reaction_10090462", "reaction_10066528", "reaction_10060231", "reaction_10077453", "reaction_10064516", "reaction_10033849", "reaction_10076984", "reaction_10058894", "reaction_10036220", "reaction_10089795", "reaction_10060041", "reaction_10041962", "reaction_10051215", "reaction_10063018", "reaction_10060614", "reaction_10033778", "reaction_10084694", "reaction_10071722", "reaction_10085352", "reaction_10046992", "reaction_10036267", "reaction_10060986", "reaction_10050169", "reaction_10035863", "reaction_10041817", "reaction_10041323", "reaction_10038060", "reaction_10064393", "reaction_10035786", "reaction_10066416", "reaction_10086336", "reaction_10042940", "reaction_10071763", "reaction_10042799", "reaction_10067733", "reaction_10035911", "reaction_10060600", "reaction_10036258", "reaction_10049004", "reaction_10042915", "reaction_10085798", "reaction_10071909", "reaction_10060590", "reaction_10034013", "reaction_10039049", "reaction_10040115", "reaction_10041437", "reaction_10036692", "reaction_10041671", "reaction_10058916", "reaction_10061251", "reaction_10042657", "reaction_10045036", "reaction_10041277", "reaction_10044211", "reaction_10076281", "reaction_10033638", "reaction_10038336", "reaction_10060429", "reaction_10083369", "reaction_10041878", "reaction_10033788", "reaction_10086033", "reaction_10090015", "reaction_10059035", "reaction_10090379", "reaction_10036001", "reaction_10048896", "reaction_10058996", "reaction_10060309", "reaction_10042929", "reaction_10086630", "reaction_10049182", "reaction_10058772", "reaction_10046984", "reaction_10051980", "reaction_10090440", "reaction_10060572", "reaction_10063020", "reaction_10058961", "reaction_10058829", "reaction_10040904", "reaction_10063610", "reaction_10085365", "reaction_10065328", "reaction_10040913", "reaction_10049163", "reaction_10065319", "reaction_10054611", "reaction_10061134", "reaction_10077658", "reaction_10048986", "reaction_10045692", "reaction_10063010", "reaction_10036231", "reaction_10058908", "reaction_10035047", "reaction_10041226", "reaction_10061011", "reaction_10090493", "reaction_10041341", "reaction_10041840", "reaction_10040672", "reaction_10061076", "reaction_10035372", "reaction_10091605", "reaction_10066249", "reaction_10080747", "reaction_10060031", "reaction_10067610", "reaction_10065213", "reaction_10041325", "reaction_10059091", "reaction_10064482", "reaction_10061122", "reaction_10090460", "reaction_10069948", "reaction_10041111", "reaction_10041170", "reaction_10045043", "reaction_10041824", "reaction_10060264", "reaction_10063420", "reaction_10060476", "reaction_10060234", "reaction_10060346", "reaction_10083544", "reaction_10059944", "reaction_10033997", "reaction_10034240", "reaction_10050446", "reaction_10043933", "reaction_10090638", "reaction_10034944", "reaction_10038938", "reaction_10047042", "reaction_10083861", "reaction_10064479", "reaction_10091286", "reaction_10059114", "reaction_10058892", "reaction_10065359", "reaction_10090162", "reaction_10049154", "reaction_10058524", "reaction_10058945", "reaction_10051973", "reaction_10067639", "reaction_10041716", "reaction_10036614", "reaction_10033737", "reaction_10058753", "reaction_10037751", "reaction_10065210", "reaction_10058819", "reaction_10064554", "reaction_10033611", "reaction_10033629", "reaction_10035435", "reaction_10059141", "reaction_10033824", "reaction_10060468", "reaction_10033697", "reaction_10033728", "reaction_10044599", "reaction_10091293", "reaction_10061131", "reaction_10041484", "reaction_10059991", "reaction_10085359", "reaction_10054592", "reaction_10066461", "reaction_10092062", "reaction_10035795", "reaction_10054585", "reaction_10041397", "reaction_10063232", "reaction_10088026", "reaction_10035426", "reaction_10086557", "reaction_10091941", "reaction_10088649", "reaction_10048988", "reaction_10061052", "reaction_10053348", "reaction_10036664", "reaction_10083800", "reaction_10087455", "reaction_10042922", "reaction_10044540", "reaction_10041345", "reaction_10036027", "reaction_10071715", "reaction_10041367", "reaction_10059094", "reaction_10088617", "reaction_10078575", "reaction_10033935", "reaction_10033833", "reaction_10054620", "reaction_10034238", "reaction_10043986", "reaction_10035861", "reaction_10034032", "reaction_10076863", "reaction_10065383", "reaction_10064445", "reaction_10044801", "reaction_10033969", "reaction_10041369", "reaction_10033579", "reaction_10061137", "reaction_10058943", "reaction_10033889", "reaction_10072825", "reaction_10061350", "reaction_10035455", "reaction_10061034", "reaction_10076375", "reaction_10052056", "reaction_10090802", "reaction_10086623", "reaction_10058785", "reaction_10090155", "reaction_10080887", "reaction_10059026", "reaction_10065445", "reaction_10061079", "reaction_10041365", "reaction_10061040", "reaction_10059853", "reaction_10041744", "reaction_10036649", "reaction_10035329", "reaction_10041728", "reaction_10090506", "reaction_10063573", "reaction_10044524", "reaction_10064534", "reaction_10060842", "reaction_10060963", "reaction_10040892", "reaction_10092065", "reaction_10073431", "reaction_10090458", "reaction_10075576", "reaction_10058948", "reaction_10041371", "reaction_10041375", "reaction_10049351", "reaction_10078393", "reaction_10042838", "reaction_10061113", "reaction_10034980", "reaction_10067622", "reaction_10040120", "reaction_10044218", "reaction_10090382", "reaction_10058774", "reaction_10066576", "reaction_10051261", "reaction_10041353", "reaction_10063530", "reaction_10090631", "reaction_10082143", "reaction_10036306", "reaction_10047765", "reaction_10063456", "reaction_10077444", "reaction_10059851", "reaction_10088867", "reaction_10076130", "reaction_10077435", "reaction_10071727", "reaction_10077004", "reaction_10042906", "reaction_10034140", "reaction_10061037", "reaction_10083115", "reaction_10051676", "reaction_10087442", "reaction_10061067", "reaction_10035812", "reaction_10066471", "reaction_10071712", "reaction_10092306", "reaction_10054382", "reaction_10054404", "reaction_10060275", "reaction_10078582", "reaction_10033746", "reaction_10090708", "reaction_10041308", "reaction_10051252", "reaction_10083572", "reaction_10038318", "reaction_10033592", "reaction_10035319", "reaction_10060938", "reaction_10034118", "reaction_10038338", "reaction_10044255", "reaction_10035009", "reaction_10076459", "reaction_10066571", "reaction_10088737", "reaction_10039047", "reaction_10061043", "reaction_10091611", "reaction_10058993", "reaction_10052043", "reaction_10083577", "reaction_10036038", "reaction_10076898", "reaction_10058913", "reaction_10066882", "reaction_10085808", "reaction_10043978", "reaction_10063430", "reaction_10063485", "reaction_10063442", "reaction_10091289", "reaction_10059984", "reaction_10059856", "reaction_10090175", "reaction_10034215", "reaction_10058826", "reaction_10036040", "reaction_10058858", "reaction_10053266", "reaction_10078701", "reaction_10034924", "reaction_10036685", "reaction_10041319", "reaction_10041179", "reaction_10043980", "reaction_10060829", "reaction_10036218", "reaction_10084410", "reaction_10049007", "reaction_10090470", "reaction_10044232", "reaction_10083211", "reaction_10078402", "reaction_10071754", "reaction_10066619", "reaction_10090681", "reaction_10090679", "reaction_10044477", "reaction_10064491", "reaction_10071643", "reaction_10041337", "reaction_10063570", "reaction_10058970", "reaction_10065225", "reaction_10041377", "reaction_10042961", "reaction_10041756", "reaction_10041172", "reaction_10035354", "reaction_10082948", "reaction_10044784", "reaction_10041486", "reaction_10038371", "reaction_10058834", "reaction_10043885", "reaction_10033681", "reaction_10058874", "reaction_10060827", "reaction_10090854", "reaction_10060295", "reaction_10041386", "reaction_10044182", "reaction_10059858", "reaction_10040881", "reaction_10066585", "reaction_10060109", "reaction_10040688", "reaction_10034206", "reaction_10035339", "reaction_10033912", "reaction_10042801", "reaction_10058896", "reaction_10090772", "reaction_10076261", "reaction_10044225", "reaction_10061014", "reaction_10076815", "reaction_10065371", "reaction_10039865", "reaction_10039604", "reaction_10076994", "reaction_10060588", "reaction_10077784", "reaction_10077758", "reaction_10033797", "reaction_10035308", "reaction_10089850", "reaction_10041799", "reaction_10066574", "reaction_10041193", "reaction_10090498", "reaction_10067240", "reaction_10090510", "reaction_10040663", "reaction_10076974", "reaction_10090696", "reaction_10045050", "reaction_10058514", "reaction_10053350", "reaction_10048978", "reaction_10060498", "reaction_10063532", "reaction_10035342", "reaction_10068748", "reaction_10065386", "reaction_10034927", "reaction_10047022", "reaction_10041293", "reaction_10064595", "reaction_10082147", "reaction_10060516", "reaction_10043903", "reaction_10061642", "reaction_10091598", "reaction_10034971", "reaction_10060917", "reaction_10074353", "reaction_10090384", "reaction_10075404", "reaction_10085788", "reaction_10058975", "reaction_10061031", "reaction_10041412", "reaction_10059847", "reaction_10044794", "reaction_10053298", "reaction_10034231", "reaction_10080517", "reaction_10083389", "reaction_10040129", "reaction_10063564", "reaction_10067634", "reaction_10085780", "reaction_10035444", "reaction_10057792", "reaction_10058899", "reaction_10060501", "reaction_10049141", "reaction_10058955", "reaction_10038347", "reaction_10058511", "reaction_10078366", "reaction_10090489", "reaction_10059000", "reaction_10044167", "reaction_10034175", "reaction_10064578", "reaction_10040112", "reaction_10035020", "reaction_10059951", "reaction_10076799", "reaction_10034989", "reaction_10085853", "reaction_10038238", "reaction_10058910", "reaction_10035038", "reaction_10065455", "reaction_10059954", "reaction_10063452", "reaction_10041393", "reaction_10040098", "reaction_10062508", "reaction_10060556", "reaction_10052027", "reaction_10063413", "reaction_10034043", "reaction_10063446", "reaction_10041339", "reaction_10041097", "reaction_10042655", "reaction_10086064", "reaction_10063437", "reaction_10081346", "reaction_10062674", "reaction_10090867", "reaction_10036012", "reaction_10036907", "reaction_10038647", "reaction_10090464", "reaction_10058751", "reaction_10041955", "reaction_10090671", "reaction_10088926", "reaction_10066569", "reaction_10040147", "reaction_10060550", "reaction_10040682", "reaction_10041197", "reaction_10073477", "reaction_10042897", "reaction_10047053", "reaction_10041343", "reaction_10088571", "reaction_10035958", "reaction_10066247", "reaction_10038918", "reaction_10044204", "reaction_10064581", "reaction_10053287", "reaction_10054393", "reaction_10086763", "reaction_10063477", "reaction_10065441", "reaction_10033806", "reaction_10044216", "reaction_10040122", "reaction_10088898", "reaction_10084129", "reaction_10081984", "reaction_10057079", "reaction_10041295", "reaction_10064526", "reaction_10057880", "reaction_10064591", "reaction_10060285", "reaction_10041831", "reaction_10061119", "reaction_10090474", "reaction_10043984", "reaction_10068755", "reaction_10051570", "reaction_10035332", "reaction_10051198", "reaction_10063448", "reaction_10034138", "reaction_10090797", "reaction_10066587", "reaction_10035007", "reaction_10046968", "reaction_10064439", "reaction_10033671", "reaction_10036238", "reaction_10046648", "reaction_10060021", "reaction_10085855", "reaction_10039887", "reaction_10077777", "reaction_10083926", "reaction_10065763", "reaction_10041297", "reaction_10036903", "reaction_10073438", "reaction_10050650", "reaction_10064565", "reaction_10076847", "reaction_10042860", "reaction_10089782", "reaction_10035029", "reaction_10034166", "reaction_10058880", "reaction_10063216", "reaction_10036209", "reaction_10081990", "reaction_10049121", "reaction_10059044", "reaction_10035977", "reaction_10041781", "reaction_10083547", "reaction_10041284", "reaction_10051589", "reaction_10060634", "reaction_10040030", "reaction_10035481", "reaction_10036247", "reaction_10060597", "reaction_10034004", "reaction_10090508", "reaction_10062701", "reaction_10041186", "reaction_10084679", "reaction_10064506", "reaction_10066401", "reaction_10041321", "reaction_10038380", "reaction_10090504", "reaction_10063508", "reaction_10081928", "reaction_10066444", "reaction_10033953", "reaction_10090392", "reaction_10038340", "reaction_10063425", "reaction_10060579", "reaction_10041684", "reaction_10086469", "reaction_10041808", "reaction_10038942", "reaction_10066458", "reaction_10064597", "reaction_10061084", "reaction_10033561", "reaction_10053361", "reaction_10054601", "reaction_10084526", "reaction_10063428", "reaction_10061125", "reaction_10034157", "reaction_10063022", "reaction_10040021", "reaction_10060207", "reaction_10060252", "reaction_10051075", "reaction_10085381", "reaction_10039242", "reaction_10035479", "reaction_10035698", "reaction_10076903", "reaction_10082155", "reaction_10059968", "reaction_10048860", "reaction_10042648", "reaction_10071729", "reaction_10044739", "reaction_10041721", "reaction_10040645", "reaction_10063249", "reaction_10060518", "reaction_10063510", "reaction_10061651", "reaction_10061017", "reaction_10071717", "reaction_10085340", "reaction_10060741", "reaction_10043971", "reaction_10065369", "reaction_10044776", "reaction_10058809", "reaction_10065381", "reaction_10044835", "reaction_10085185", "reaction_10078529", "reaction_10033755", "reaction_10086543", "reaction_10038231", "reaction_10041347", "reaction_10064355", "reaction_10040654", "reaction_10043924", "reaction_10048889", "reaction_10081988", "reaction_10075607", "reaction_10034071", "reaction_10081986", "reaction_10064567", "reaction_10090477", "reaction_10067254", "reaction_10046623", "reaction_10043917", "reaction_10089230", "reaction_10044851", "reaction_10065760", "reaction_10080756", "reaction_10050637", "reaction_10061024", "reaction_10063633", "reaction_10040152", "reaction_10061006", "reaction_10044270", "reaction_10039240", "reaction_10083864", "reaction_10045029", "reaction_10067425", "reaction_10041206", "reaction_10083496", "reaction_10049143", "reaction_10090856", "reaction_10041373", "reaction_10033868", "reaction_10060535", "reaction_10086748", "reaction_10054395", "reaction_10063440", "reaction_10035838", "reaction_10067247", "reaction_10059014", "reaction_10082136", "reaction_10077496", "reaction_10043910", "reaction_10049346", "reaction_10088744", "reaction_10060685", "reaction_10041894", "reaction_10076389", "reaction_10071483", "reaction_10085310", "reaction_10063801", "reaction_10077835", "reaction_10083889", "reaction_10047044", "reaction_10090799", "reaction_10065223", "reaction_10044828", "reaction_10058923", "reaction_10039749", "reaction_10039890", "reaction_10044280", "reaction_10048727", "reaction_10077734", "reaction_10049161", "reaction_10066473", "reaction_10041737", "reaction_10085024", "reaction_10041379", "reaction_10072894", "reaction_10066602", "reaction_10044837", "reaction_10070971", "reaction_10060012", "reaction_10061046", "reaction_10090386", "reaction_10058877", "reaction_10047809", "reaction_10090611", "reaction_10083092", "reaction_10081977", "reaction_10076450", "reaction_10071924", "reaction_10057787", "reaction_10086248", "reaction_10061402", "reaction_10036229", "reaction_10035453", "reaction_10040107", "reaction_10060956", "reaction_10059121", "reaction_10061049", "reaction_10034921", "reaction_10040924", "reaction_10060951", "reaction_10076360", "reaction_10040117", "reaction_10083873", "reaction_10057684", "reaction_10041502", "reaction_10038316", "reaction_10058980", "reaction_10047033", "reaction_10057032", "reaction_10062984", "reaction_10044533", "reaction_10061128", "reaction_10058990", "reaction_10085806", "reaction_10057023", "reaction_10033716", "reaction_10059021", "reaction_10060514", "reaction_10044634", "reaction_10086550", "reaction_10060293", "reaction_10060611", "reaction_10033979", "reaction_10085374", "reaction_10052040", "reaction_10091613", "reaction_10064584", "reaction_10058934", "reaction_10036023", "reaction_10064500", "reaction_10059004", "reaction_10058885", "reaction_10090388", "reaction_10041355", "reaction_10044275", "reaction_10059860", "reaction_10059961", "reaction_10048995", "reaction_10064593", "reaction_10049116", "reaction_10090822", "reaction_10086750", "reaction_10053363", "reaction_10060316", "reaction_10036928", "reaction_10090819", "reaction_10058722", "reaction_10077001", "reaction_10065362", "reaction_10090480", "reaction_10035415", "reaction_10041351", "reaction_10041395", "reaction_10058985", "reaction_10076406", "reaction_10081349", "reaction_10076468", "reaction_10088019", "reaction_10041335", "reaction_10077751", "reaction_10038320", "reaction_10060218", "reaction_10064511", "reaction_10043964", "reaction_10042936", "reaction_10076144", "reaction_10033988", "reaction_10082889", "reaction_10090774", "reaction_10051264", "reaction_10059082", "reaction_10048903", "reaction_10063586", "reaction_10041217", "reaction_10041765", "reaction_10044260", "reaction_10059150", "reaction_10077793", "reaction_10091936", "reaction_10064391" ] }, "R-BTA-1474244": { "id": "pathway_10093318", "reactome": "R-BTA-1474244", "name": "Extracellular matrix organization", "reactions": [ "reaction_10087587", "reaction_10069313", "reaction_10087571", "reaction_10087583", "reaction_10063799", "reaction_10065929", "reaction_10064649", "reaction_10076984", "reaction_10059787", "reaction_10062071", "reaction_10059651", "reaction_10059598", "reaction_10063839", "reaction_10058705", "reaction_10059869", "reaction_10059702", "reaction_10087565", "reaction_10062352", "reaction_10087573", "reaction_10059533", "reaction_10064705", "reaction_10064953", "reaction_10087543", "reaction_10087626", "reaction_10059674", "reaction_10059913", "reaction_10044515", "reaction_10064435", "reaction_10059918", "reaction_10060191", "reaction_10058193", "reaction_10065292", "reaction_10060187", "reaction_10062377", "reaction_10064959", "reaction_10058561", "reaction_10065691", "reaction_10065336", "reaction_10065819", "reaction_10087581", "reaction_10087577", "reaction_10087563", "reaction_10065300", "reaction_10087589", "reaction_10087324", "reaction_10059923", "reaction_10065751", "reaction_10068885", "reaction_10064337", "reaction_10065555", "reaction_10069412", "reaction_10061787", "reaction_10059902", "reaction_10059744", "reaction_10060003", "reaction_10059441", "reaction_10087567", "reaction_10059689", "reaction_10059731", "reaction_10042253", "reaction_10087569", "reaction_10065435", "reaction_10059804", "reaction_10062058", "reaction_10087585", "reaction_10087628", "reaction_10064437", "reaction_10087579" ] }, "R-BTA-212436": { "id": "pathway_10092436", "reactome": "R-BTA-212436", "name": "Generic Transcription Pathway", "reactions": [ "reaction_10080722", "reaction_10091049", "reaction_10082931", "reaction_10087910", "reaction_10080730", "reaction_10033592", "reaction_10081323", "reaction_10088554", "reaction_10088876", "reaction_10066764", "reaction_10078349", "reaction_10086534", "reaction_10034166", "reaction_10087889", "reaction_10088872", "reaction_10082934", "reaction_10089610", "reaction_10081563", "reaction_10066670", "reaction_10072595", "reaction_10084922", "reaction_10076341", "reaction_10085761", "reaction_10078474", "reaction_10072557", "reaction_10086241", "reaction_10088546", "reaction_10078720", "reaction_10044726", "reaction_10088006", "reaction_10084881", "reaction_10088534", "reaction_10072571", "reaction_10063400", "reaction_10080457", "reaction_10044446", "reaction_10078731", "reaction_10086509", "reaction_10084947", "reaction_10088596", "reaction_10033755", "reaction_10081522", "reaction_10089574", "reaction_10091184", "reaction_10066704", "reaction_10066684", "reaction_10086581", "reaction_10072614", "reaction_10077955", "reaction_10089578", "reaction_10089681", "reaction_10084903", "reaction_10083077", "reaction_10086231", "reaction_10088584", "reaction_10081595", "reaction_10066712", "reaction_10086716", "reaction_10080811", "reaction_10080797", "reaction_10086638", "reaction_10066745", "reaction_10081380", "reaction_10091017", "reaction_10081877", "reaction_10088490", "reaction_10063390", "reaction_10086493", "reaction_10084895", "reaction_10091089", "reaction_10089640", "reaction_10082923", "reaction_10083072", "reaction_10087997", "reaction_10088564", "reaction_10046588", "reaction_10064933", "reaction_10086587", "reaction_10091033", "reaction_10086458", "reaction_10086525", "reaction_10072591", "reaction_10086589", "reaction_10081293", "reaction_10072550", "reaction_10084935", "reaction_10066724", "reaction_10083092", "reaction_10086155", "reaction_10054279", "reaction_10045744", "reaction_10089357", "reaction_10078408", "reaction_10071262", "reaction_10081326", "reaction_10078658", "reaction_10086518", "reaction_10088482", "reaction_10087900", "reaction_10091029", "reaction_10081305", "reaction_10081622", "reaction_10038647", "reaction_10066870", "reaction_10080738", "reaction_10091023", "reaction_10081291", "reaction_10033535", "reaction_10081629", "reaction_10080789", "reaction_10081541", "reaction_10089679", "reaction_10088887", "reaction_10088012", "reaction_10084909", "reaction_10081278", "reaction_10081274", "reaction_10088542", "reaction_10086541", "reaction_10081470", "reaction_10084911", "reaction_10081602", "reaction_10066737", "reaction_10081530", "reaction_10086502", "reaction_10087862", "reaction_10091096", "reaction_10046681", "reaction_10081499", "reaction_10081889", "reaction_10081286", "reaction_10086724", "reaction_10081561" ] }, "R-BTA-73894": { "id": "pathway_10092662", "reactome": "R-BTA-73894", "name": "DNA Repair", "reactions": [ "reaction_10076071", "reaction_10076009", "reaction_10074670", "reaction_10074739", "reaction_10074558", "reaction_10076293", "reaction_10073279", "reaction_10091222", "reaction_10036709", "reaction_10074747", "reaction_10036736", "reaction_10076312", "reaction_10076303", "reaction_10075165", "reaction_10071769", "reaction_10076341", "reaction_10075181", "reaction_10074736", "reaction_10036869", "reaction_10036782", "reaction_10036767", "reaction_10071638", "reaction_10077591", "reaction_10075323", "reaction_10076327", "reaction_10091566", "reaction_10036760", "reaction_10075304", "reaction_10073290", "reaction_10074798", "reaction_10071617", "reaction_10074720", "reaction_10071630", "reaction_10036844", "reaction_10088526", "reaction_10091211", "reaction_10073275", "reaction_10075037", "reaction_10091233", "reaction_10071607", "reaction_10084497", "reaction_10036886", "reaction_10075326", "reaction_10071622", "reaction_10076343", "reaction_10076332", "reaction_10074759", "reaction_10036805", "reaction_10036716", "reaction_10074761", "reaction_10075173", "reaction_10076347", "reaction_10071628", "reaction_10071765", "reaction_10076298", "reaction_10074550", "reaction_10036661", "reaction_10076339", "reaction_10036743", "reaction_10035720", "reaction_10075151", "reaction_10036729", "reaction_10071640", "reaction_10072876", "reaction_10076286", "reaction_10075319", "reaction_10077108", "reaction_10036853", "reaction_10036798", "reaction_10074679", "reaction_10077593", "reaction_10075306", "reaction_10077016", "reaction_10071767", "reaction_10077396", "reaction_10073302", "reaction_10036791", "reaction_10075295", "reaction_10073254", "reaction_10035846", "reaction_10074695", "reaction_10074677", "reaction_10035712", "reaction_10076329", "reaction_10077625", "reaction_10074453", "reaction_10074692", "reaction_10074877", "reaction_10091240", "reaction_10072883", "reaction_10068854", "reaction_10076334", "reaction_10036879" ] }, "R-BTA-373076": { "id": "pathway_10093502", "reactome": "R-BTA-373076", "name": "Class A/1 (Rhodopsin-like receptors)", "reactions": [ "reaction_10081580", "reaction_10047236", "reaction_10045406", "reaction_10047864", "reaction_10045384", "reaction_10051217", "reaction_10067360", "reaction_10091812", "reaction_10045180", "reaction_10047362", "reaction_10048174", "reaction_10090968", "reaction_10049570", "reaction_10047398", "reaction_10047334", "reaction_10047860", "reaction_10045268", "reaction_10067350", "reaction_10049585", "reaction_10053335", "reaction_10067364", "reaction_10047851", "reaction_10091037", "reaction_10045350", "reaction_10048172", "reaction_10047394", "reaction_10083878", "reaction_10047214", "reaction_10083880", "reaction_10045324", "reaction_10045280", "reaction_10047354", "reaction_10084702", "reaction_10047210", "reaction_10047256", "reaction_10048208", "reaction_10047396", "reaction_10045072", "reaction_10049617", "reaction_10049639", "reaction_10049699", "reaction_10091556", "reaction_10046919", "reaction_10047853", "reaction_10047364", "reaction_10046953", "reaction_10091929", "reaction_10090956", "reaction_10047378", "reaction_10047374", "reaction_10048176", "reaction_10083937", "reaction_10047376", "reaction_10047987", "reaction_10046915", "reaction_10047212", "reaction_10049661", "reaction_10054775", "reaction_10049663", "reaction_10045168", "reaction_10047989", "reaction_10067362", "reaction_10045156", "reaction_10045094", "reaction_10047857", "reaction_10045332", "reaction_10047206", "reaction_10048214", "reaction_10090925", "reaction_10049683", "reaction_10047226", "reaction_10049637", "reaction_10091825", "reaction_10046731", "reaction_10045292", "reaction_10049659", "reaction_10047366", "reaction_10091763", "reaction_10046729", "reaction_10048003", "reaction_10049641", "reaction_10046763", "reaction_10045362", "reaction_10047234", "reaction_10049520", "reaction_10090964", "reaction_10049645", "reaction_10049615", "reaction_10046917", "reaction_10047866", "reaction_10045196", "reaction_10053333", "reaction_10046733", "reaction_10047332", "reaction_10078536", "reaction_10047862", "reaction_10048178", "reaction_10049657", "reaction_10048180", "reaction_10046735", "reaction_10090960", "reaction_10047483", "reaction_10047868", "reaction_10047870", "reaction_10047380", "reaction_10067358", "reaction_10046773", "reaction_10047238", "reaction_10047224", "reaction_10047222", "reaction_10045106" ] }, "R-BTA-2262752": { "id": "pathway_10092554", "reactome": "R-BTA-2262752", "name": "Cellular responses to stress", "reactions": [ "reaction_10066630", "reaction_10056408", "reaction_10067722", "reaction_10068716", "reaction_10069684", "reaction_10056702", "reaction_10071241", "reaction_10068899", "reaction_10078369", "reaction_10034166", "reaction_10091351", "reaction_10067993", "reaction_10050231", "reaction_10066786", "reaction_10091404", "reaction_10067416", "reaction_10076341", "reaction_10074446", "reaction_10092287", "reaction_10092269", "reaction_10067731", "reaction_10068008", "reaction_10068959", "reaction_10092214", "reaction_10047807", "reaction_10056737", "reaction_10071208", "reaction_10074429", "reaction_10088964", "reaction_10092308", "reaction_10056688", "reaction_10080786", "reaction_10067955", "reaction_10068022", "reaction_10092310", "reaction_10066876", "reaction_10056719", "reaction_10050218", "reaction_10056754", "reaction_10076343", "reaction_10066857", "reaction_10067375", "reaction_10066873", "reaction_10041950", "reaction_10074431", "reaction_10050192", "reaction_10091336", "reaction_10076298", "reaction_10056759", "reaction_10040355", "reaction_10056679", "reaction_10091356", "reaction_10092271", "reaction_10050256", "reaction_10091354", "reaction_10040636", "reaction_10068575", "reaction_10069854", "reaction_10076891", "reaction_10066779", "reaction_10071127", "reaction_10066832", "reaction_10056761", "reaction_10038647", "reaction_10092239", "reaction_10092237", "reaction_10066870", "reaction_10056757", "reaction_10091365", "reaction_10087866", "reaction_10091401", "reaction_10067398", "reaction_10067744", "reaction_10050208", "reaction_10052914", "reaction_10039508", "reaction_10068578", "reaction_10067735", "reaction_10092227", "reaction_10092293", "reaction_10074453", "reaction_10071313", "reaction_10092225", "reaction_10068854", "reaction_10092289", "reaction_10092312", "reaction_10067388", "reaction_10092273" ] }, "R-BTA-5653656": { "id": "pathway_10093214", "reactome": "R-BTA-5653656", "name": "Vesicle-mediated transport", "reactions": [ "reaction_10085988", "reaction_10085313", "reaction_10065163", "reaction_10076775", "reaction_10076590", "reaction_10043649", "reaction_10085166", "reaction_10044826", "reaction_10076708", "reaction_10083006", "reaction_10076610", "reaction_10040842", "reaction_10082999", "reaction_10084276", "reaction_10050458", "reaction_10083143", "reaction_10083004", "reaction_10086019", "reaction_10076584", "reaction_10083458", "reaction_10086097", "reaction_10076696", "reaction_10084757", "reaction_10076635", "reaction_10076736", "reaction_10091753", "reaction_10076586", "reaction_10076706", "reaction_10084822", "reaction_10045538", "reaction_10084228", "reaction_10084819", "reaction_10040864", "reaction_10064765", "reaction_10085116", "reaction_10083056", "reaction_10084238", "reaction_10040857", "reaction_10064753", "reaction_10083712", "reaction_10085932", "reaction_10082026", "reaction_10084246", "reaction_10064757", "reaction_10084261", "reaction_10083377", "reaction_10082045", "reaction_10082038", "reaction_10086209", "reaction_10083187", "reaction_10083149", "reaction_10083425", "reaction_10083380", "reaction_10084824", "reaction_10083340", "reaction_10040851", "reaction_10040967", "reaction_10084291", "reaction_10086136", "reaction_10065173", "reaction_10083342", "reaction_10040961", "reaction_10076778", "reaction_10083767", "reaction_10085134", "reaction_10040955", "reaction_10083451", "reaction_10085264", "reaction_10083179", "reaction_10086182", "reaction_10076698", "reaction_10086054" ] }, "R-BTA-196849": { "id": "pathway_10092518", "reactome": "R-BTA-196849", "name": "Metabolism of water-soluble vitamins and cofactors", "reactions": [ "reaction_10066450", "reaction_10066471", "reaction_10092306", "reaction_10066430", "reaction_10041962", "reaction_10085352", "reaction_10053352", "reaction_10066571", "reaction_10041817", "reaction_10041781", "reaction_10042940", "reaction_10042799", "reaction_10067733", "reaction_10066882", "reaction_10042915", "reaction_10066401", "reaction_10041772", "reaction_10066444", "reaction_10053266", "reaction_10042657", "reaction_10041808", "reaction_10066458", "reaction_10053361", "reaction_10086630", "reaction_10042929", "reaction_10066619", "reaction_10071643", "reaction_10042648", "reaction_10041756", "reaction_10085365", "reaction_10082078", "reaction_10066585", "reaction_10041840", "reaction_10041790", "reaction_10041824", "reaction_10041799", "reaction_10066574", "reaction_10053350", "reaction_10086748", "reaction_10041753", "reaction_10088666", "reaction_10041838", "reaction_10065210", "reaction_10053298", "reaction_10041737", "reaction_10066473", "reaction_10066602", "reaction_10085359", "reaction_10066461", "reaction_10081977", "reaction_10053348", "reaction_10042922", "reaction_10081339", "reaction_10042655", "reaction_10081346", "reaction_10066502", "reaction_10041955", "reaction_10041975", "reaction_10066569", "reaction_10033889", "reaction_10082068", "reaction_10085374", "reaction_10076485", "reaction_10086623", "reaction_10085362", "reaction_10049170", "reaction_10066526", "reaction_10041744", "reaction_10053287", "reaction_10086750", "reaction_10086763", "reaction_10053363", "reaction_10081984", "reaction_10081349", "reaction_10041831", "reaction_10076254", "reaction_10066576", "reaction_10042936", "reaction_10082143", "reaction_10088867", "reaction_10041765", "reaction_10042906", "reaction_10066587", "reaction_10087442", "reaction_10066528" ] }, "R-BTA-15869": { "id": "pathway_10092548", "reactome": "R-BTA-15869", "name": "Metabolism of nucleotides", "reactions": [ "reaction_10088624", "reaction_10036683", "reaction_10083926", "reaction_10065763", "reaction_10051215", "reaction_10035319", "reaction_10036267", "reaction_10035029", "reaction_10034166", "reaction_10035009", "reaction_10036209", "reaction_10036308", "reaction_10036247", "reaction_10035481", "reaction_10065378", "reaction_10036258", "reaction_10036692", "reaction_10034924", "reaction_10036685", "reaction_10083876", "reaction_10034998", "reaction_10051075", "reaction_10034962", "reaction_10035479", "reaction_10035698", "reaction_10036001", "reaction_10036938", "reaction_10082948", "reaction_10035354", "reaction_10065319", "reaction_10065328", "reaction_10065369", "reaction_10065381", "reaction_10036231", "reaction_10035047", "reaction_10035339", "reaction_10065371", "reaction_10065760", "reaction_10035308", "reaction_10083864", "reaction_10077890", "reaction_10083861", "reaction_10035342", "reaction_10065386", "reaction_10034927", "reaction_10034953", "reaction_10065359", "reaction_10034971", "reaction_10036614", "reaction_10083889", "reaction_10035435", "reaction_10036207", "reaction_10035444", "reaction_10035426", "reaction_10035020", "reaction_10034989", "reaction_10035038", "reaction_10036229", "reaction_10035453", "reaction_10034921", "reaction_10083852", "reaction_10036907", "reaction_10083873", "reaction_10065383", "reaction_10035345", "reaction_10035464", "reaction_10091727", "reaction_10035455", "reaction_10088571", "reaction_10036928", "reaction_10036649", "reaction_10036909", "reaction_10035329", "reaction_10065362", "reaction_10036256", "reaction_10034980", "reaction_10036306", "reaction_10035332", "reaction_10035011", "reaction_10035007", "reaction_10036238" ] }, "R-BTA-112316": { "id": "pathway_10092500", "reactome": "R-BTA-112316", "name": "Neuronal System", "reactions": [ "reaction_10078674", "reaction_10046552", "reaction_10051085", "reaction_10078488", "reaction_10083793", "reaction_10046868", "reaction_10078518", "reaction_10033746", "reaction_10039653", "reaction_10081481", "reaction_10050514", "reaction_10039676", "reaction_10091525", "reaction_10049090", "reaction_10057639", "reaction_10051989", "reaction_10057607", "reaction_10049583", "reaction_10033755", "reaction_10052013", "reaction_10052018", "reaction_10078566", "reaction_10050517", "reaction_10057399", "reaction_10054361", "reaction_10091067", "reaction_10051521", "reaction_10057616", "reaction_10057350", "reaction_10057682", "reaction_10071437", "reaction_10057365", "reaction_10039664", "reaction_10057656", "reaction_10078466", "reaction_10057588", "reaction_10046151", "reaction_10054318", "reaction_10045455", "reaction_10078446", "reaction_10051999", "reaction_10057665", "reaction_10038000", "reaction_10045419", "reaction_10045421", "reaction_10044941", "reaction_10044461", "reaction_10054372", "reaction_10045423", "reaction_10045444", "reaction_10088657", "reaction_10078464", "reaction_10057390", "reaction_10036981", "reaction_10051498", "reaction_10044076", "reaction_10044540", "reaction_10078522", "reaction_10090547", "reaction_10084356", "reaction_10057418", "reaction_10078682", "reaction_10044086", "reaction_10083789", "reaction_10078600", "reaction_10057569", "reaction_10049478", "reaction_10051525", "reaction_10051523", "reaction_10046153", "reaction_10039651", "reaction_10091075", "reaction_10091521", "reaction_10045466" ] }, "R-BTA-1630316": { "id": "pathway_10093122", "reactome": "R-BTA-1630316", "name": "Glycosaminoglycan metabolism", "reactions": [ "reaction_10061395", "reaction_10062984", "reaction_10064595", "reaction_10063520", "reaction_10061642", "reaction_10039887", "reaction_10063249", "reaction_10063510", "reaction_10061350", "reaction_10063610", "reaction_10060293", "reaction_10061651", "reaction_10060685", "reaction_10062697", "reaction_10060741", "reaction_10063801", "reaction_10060827", "reaction_10061612", "reaction_10091291", "reaction_10060295", "reaction_10063010", "reaction_10063803", "reaction_10060671", "reaction_10062655", "reaction_10063216", "reaction_10064355", "reaction_10039890", "reaction_10064593", "reaction_10091293", "reaction_10048727", "reaction_10064393", "reaction_10060678", "reaction_10063807", "reaction_10063477", "reaction_10051589", "reaction_10060825", "reaction_10060634", "reaction_10060842", "reaction_10060625", "reaction_10060031", "reaction_10063485", "reaction_10062701", "reaction_10063232", "reaction_10091289", "reaction_10063805", "reaction_10061402", "reaction_10063508", "reaction_10060285", "reaction_10063014", "reaction_10061251", "reaction_10063633", "reaction_10064353", "reaction_10062508", "reaction_10063530", "reaction_10064597", "reaction_10051570", "reaction_10060829", "reaction_10062463", "reaction_10063022", "reaction_10063603", "reaction_10063586", "reaction_10062674", "reaction_10063532", "reaction_10091286", "reaction_10064391" ] }, "R-BTA-9716542": { "id": "pathway_10093370", "reactome": "R-BTA-9716542", "name": "Signaling by Rho GTPases, Miro GTPases and RHOBTB3", "reactions": [ "reaction_10089937", "reaction_10073796", "reaction_10090087", "reaction_10073716", "reaction_10090119", "reaction_10090082", "reaction_10091994", "reaction_10090125", "reaction_10090339", "reaction_10063374", "reaction_10092205", "reaction_10091884", "reaction_10063353", "reaction_10090198", "reaction_10073525", "reaction_10068933", "reaction_10068939", "reaction_10073577", "reaction_10090246", "reaction_10089985", "reaction_10073569", "reaction_10089149", "reaction_10043461", "reaction_10091169", "reaction_10090330", "reaction_10091180", "reaction_10090306", "reaction_10073507", "reaction_10090089", "reaction_10089972", "reaction_10090349", "reaction_10073557", "reaction_10089947", "reaction_10092382", "reaction_10089011", "reaction_10090098", "reaction_10091878", "reaction_10089860", "reaction_10090091", "reaction_10073806", "reaction_10090103", "reaction_10091921", "reaction_10091902", "reaction_10092380", "reaction_10092002", "reaction_10091832", "reaction_10092394", "reaction_10090311", "reaction_10073547", "reaction_10092392", "reaction_10091896", "reaction_10092022", "reaction_10090115", "reaction_10073731", "reaction_10073561", "reaction_10091175", "reaction_10089952", "reaction_10090145", "reaction_10073549", "reaction_10089888", "reaction_10090009", "reaction_10090011", "reaction_10091916", "reaction_10073842", "reaction_10089930", "reaction_10092203", "reaction_10072515", "reaction_10073503", "reaction_10092208", "reaction_10073755", "reaction_10090077", "reaction_10073493", "reaction_10090369", "reaction_10092364", "reaction_10089890", "reaction_10090203", "reaction_10092370", "reaction_10090266", "reaction_10091864", "reaction_10092020", "reaction_10073559" ] } }, "reaction_dictionary": { "reaction_10087663": { "compartment": "compartment_70101", "id": "reaction_10087663", "reactome": "R-BTA-8950181", "name": "Y693-STAT4 dimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087657" ], "products": [ "species_10087661" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087795": { "compartment": "compartment_70101", "id": "reaction_10087795", "reactome": "R-BTA-8950778", "name": "p-Y693-STAT4 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087655" ], "products": [ "species_10087657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087650": { "compartment": "compartment_70101", "id": "reaction_10087650", "reactome": "R-BTA-8950179", "name": "IL12B translocates from the cytosol to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087648" ], "products": [ "species_10049902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077926", "ENSBTAT00000077926" ] }, "reaction_10087732": { "compartment": "compartment_17957", "id": "reaction_10087732", "reactome": "R-BTA-8950410", "name": "IL12B:IL12B translocates from ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087728" ], "products": [ "species_10087730" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10088519": { "compartment": "compartment_70101", "id": "reaction_10088519", "reactome": "R-BTA-8952807", "name": "p-Y693-STAT4 dissociates after IL12:IL12R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088517" ], "products": [ "species_10087655" ], "modifiers": [], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1N0R2", "ENSBTAT00000030584", "ENSBTAT00000030584" ] }, "reaction_10045423": { "compartment": "compartment_984", "id": "reaction_10045423", "reactome": "R-BTA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10046151": { "compartment": "compartment_70101", "id": "reaction_10046151", "reactome": "R-BTA-379382", "name": "MAOA:FAD deaminates DA to DOPAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_159362" ], "products": [ "species_9677997", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10046153": { "compartment": "compartment_70101", "id": "reaction_10046153", "reactome": "R-BTA-379395", "name": "MAOA:FAD deaminates 3MT to HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954997", "species_29356", "species_29368" ], "products": [ "species_9677992", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10088657": { "compartment": "compartment_70101", "id": "reaction_10088657", "reactome": "R-BTA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10088654", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003905" ] }, "reaction_10046552": { "compartment": "compartment_5460", "id": "reaction_10046552", "reactome": "R-BTA-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_380598" ], "products": [ "species_113529", "species_380593", "species_29362" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10038000": { "compartment": "compartment_70101", "id": "reaction_10038000", "reactome": "R-BTA-141186", "name": "MAOA:FAD oxidatively deaminates of 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_209914", "species_29368" ], "products": [ "species_500604", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10078658": { "compartment": "compartment_70101", "id": "reaction_10078658", "reactome": "R-BTA-6798044", "name": "BTG2 binds CCR4-NOT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078654", "species_10078604" ], "products": [ "species_10078656" ], "modifiers": [], "additional_components": [ "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100", "ENSBTAT00000020860", "F1MNK6", "ENSBTAT00000020860", "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100" ] }, "reaction_10081380": { "compartment": "compartment_70101", "id": "reaction_10081380", "reactome": "R-BTA-6801675", "name": "PLK2 phosphorylates NPM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10081359" ], "products": [ "species_29370", "species_10081373" ], "modifiers": [ [ "species_10081377", "catalyst" ] ], "additional_components": [ "A0A3Q1LXL7", "ENSBTAT00000054559", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "ENSBTAT00000022307" ] }, "reaction_10081499": { "compartment": "compartment_70101", "id": "reaction_10081499", "reactome": "R-BTA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037648" ], "products": [ "species_10037650" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012154", "Q0VC36", "ENSBTAT00000012154" ] }, "reaction_10078349": { "compartment": "compartment_7660", "id": "reaction_10078349", "reactome": "R-BTA-6791235", "name": "GADD45A binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077951", "species_10078345" ], "products": [ "species_10078347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033450", "ENSBTAT00000044590", "Q2TA06", "ENSBTAT00000044590", "Q3ZBN6", "ENSBTAT00000033450" ] }, "reaction_10077955": { "compartment": "compartment_7660", "id": "reaction_10077955", "reactome": "R-BTA-6791109", "name": "GADD45A binds PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039892", "species_10077951" ], "products": [ "species_10077953" ], "modifiers": [], "additional_components": [ "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000033450", "Q3ZBN6", "ENSBTAT00000033450", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10088542": { "compartment": "compartment_7660", "id": "reaction_10088542", "reactome": "R-BTA-8953013", "name": "E2F7 binds E2F8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530", "species_10088538" ], "products": [ "species_10088540" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10088546": { "compartment": "compartment_7660", "id": "reaction_10088546", "reactome": "R-BTA-8953037", "name": "E2F8 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088538" ], "products": [ "species_10088544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675" ] }, "reaction_10088534": { "compartment": "compartment_7660", "id": "reaction_10088534", "reactome": "R-BTA-8952996", "name": "E2F7 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530" ], "products": [ "species_10088532" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10041386": { "compartment": "compartment_70101", "id": "reaction_10041386", "reactome": "R-BTA-193964", "name": "CYP21A2 21-hydroxylates PROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_194037", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041393": { "compartment": "compartment_5460", "id": "reaction_10041393", "reactome": "R-BTA-193965", "name": "CYP11B2 oxidises 18HCORST to ALDO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194012", "species_113533", "species_113529", "species_113600" ], "products": [ "species_193982", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041269": { "compartment": "compartment_70101", "id": "reaction_10041269", "reactome": "R-BTA-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041267", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10041397": { "compartment": "compartment_5460", "id": "reaction_10041397", "reactome": "R-BTA-193995", "name": "CYP11B2 18-hydroxylates CORST to 18HCORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_194005", "species_113600" ], "products": [ "species_194012", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041719": { "compartment": "compartment_70101", "id": "reaction_10041719", "reactome": "R-BTA-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_196344", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041415": { "compartment": "compartment_5460", "id": "reaction_10041415", "reactome": "R-BTA-194017", "name": "CYP11B2 oxidises 11DCORST to CORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193988", "species_113600" ], "products": [ "species_113563", "species_194005", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10076281": { "compartment": "compartment_70101", "id": "reaction_10076281", "reactome": "R-BTA-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10076278", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008272" ] }, "reaction_10077113": { "compartment": "compartment_5460", "id": "reaction_10077113", "reactome": "R-BTA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10077110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002073" ] }, "reaction_10041277": { "compartment": "compartment_70101", "id": "reaction_10041277", "reactome": "R-BTA-193060", "name": "CYP19A1 hydroxylates ANDST to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193079", "species_29364" ], "products": [ "species_29356", "species_193066", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10051676": { "compartment": "compartment_70101", "id": "reaction_10051676", "reactome": "R-BTA-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193066", "species_29364" ], "products": [ "species_193132", "species_29366" ], "modifiers": [ [ "species_10051673", "catalyst" ] ], "additional_components": [ "Q1JQD0", "ENSBTAT00000064720" ] }, "reaction_10041299": { "compartment": "compartment_70101", "id": "reaction_10041299", "reactome": "R-BTA-193143", "name": "CYP19A1 hydroxylates TEST to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_193057" ], "products": [ "species_193132", "species_29356", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10084679": { "compartment": "compartment_70101", "id": "reaction_10084679", "reactome": "R-BTA-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10084676", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004193" ] }, "reaction_10041692": { "compartment": "compartment_70616", "id": "reaction_10041692", "reactome": "R-BTA-196086", "name": "Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041690" ], "products": [ "species_193156", "species_10041688" ], "modifiers": [], "additional_components": [ "Q28918", "ENSBTAT00000047426", "species_193840", "ENSBTAT00000047426" ] }, "reaction_10041716": { "compartment": "compartment_17906", "id": "reaction_10041716", "reactome": "R-BTA-196126", "name": "CHOL translocates from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041714", "species_10041688" ], "products": [ "species_10041712", "species_10041690" ], "modifiers": [], "additional_components": [ "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "species_193840", "ENSBTAT00000047426", "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "Q28918", "ENSBTAT00000047426", "species_193840" ] }, "reaction_10041684": { "compartment": "compartment_70101", "id": "reaction_10041684", "reactome": "R-BTA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10041290": { "compartment": "compartment_70101", "id": "reaction_10041290", "reactome": "R-BTA-193070", "name": "CYP17A1 cleaves 17aHPREG to DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193124", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_176626" ], "modifiers": [ [ "species_10041281", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189", "ENSBTAT00000010386" ] }, "reaction_10050650": { "compartment": "compartment_70101", "id": "reaction_10050650", "reactome": "R-BTA-469659", "name": "SRD5A1 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10050647", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020570", "ENSBTAT00000010386" ] }, "reaction_10041293": { "compartment": "compartment_70101", "id": "reaction_10041293", "reactome": "R-BTA-193072", "name": "CYP17A1 17-hydroxylates P4 to 17aHPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193092" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041295": { "compartment": "compartment_70101", "id": "reaction_10041295", "reactome": "R-BTA-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176626", "species_29360" ], "products": [ "species_70106", "species_193079", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "ENSBTAT00000010386" ] }, "reaction_10092062": { "compartment": "compartment_70101", "id": "reaction_10092062", "reactome": "R-BTA-9705713", "name": "SRD5A2 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10092059", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004043", "ENSBTAT00000010386" ] }, "reaction_10041297": { "compartment": "compartment_70101", "id": "reaction_10041297", "reactome": "R-BTA-193099", "name": "CYP17A1 cleaves 17aHPROG to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_193079" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10092065": { "compartment": "compartment_70101", "id": "reaction_10092065", "reactome": "R-BTA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10069495", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855", "ENSBTAT00000010386" ] }, "reaction_10041284": { "compartment": "compartment_70101", "id": "reaction_10041284", "reactome": "R-BTA-193068", "name": "CYP17A1 17-hydroxylates PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193124" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041721": { "compartment": "compartment_70101", "id": "reaction_10041721", "reactome": "R-BTA-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_196366", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10057880": { "compartment": "compartment_984", "id": "reaction_10057880", "reactome": "R-BTA-1449687", "name": "Corticosteroids bind to CBG in blood", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1449707", "species_10057876" ], "products": [ "species_10057878" ], "modifiers": [], "additional_components": [ "species_193982", "species_193055", "species_194011", "species_193988", "ENSBTAT00000023402", "E1BF81", "ENSBTAT00000023402", "species_193982", "species_193055", "species_194011", "species_193988" ] }, "reaction_10041424": { "compartment": "compartment_17957", "id": "reaction_10041424", "reactome": "R-BTA-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193977", "species_29366" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10041421", "catalyst" ] ], "additional_components": [ "F6PTG3", "ENSBTAT00000020078" ] }, "reaction_10041379": { "compartment": "compartment_70101", "id": "reaction_10041379", "reactome": "R-BTA-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041395": { "compartment": "compartment_70101", "id": "reaction_10041395", "reactome": "R-BTA-193981", "name": "CYP21A2 oxidises 17HPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_193966", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041412": { "compartment": "compartment_5460", "id": "reaction_10041412", "reactome": "R-BTA-193997", "name": "CYP11B1 oxidises 11DCORT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193998", "species_113529", "species_113600" ], "products": [ "species_113563", "species_194011", "species_113521" ], "modifiers": [ [ "species_10041409", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "F1MG97", "ENSBTAT00000055451", "F1MU47", "ENSBTAT00000006034", "F1MWH3", "ENSBTAT00000055451", "ENSBTAT00000010386" ] }, "reaction_10034240": { "compartment": "compartment_70101", "id": "reaction_10034240", "reactome": "R-BTA-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29398", "species_73473" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10089721": { "compartment": "compartment_5460", "id": "reaction_10089721", "reactome": "R-BTA-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089717", "species_9010792" ], "products": [ "species_10089719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011523", "F6Q200", "ENSBTAT00000011523" ] }, "reaction_10089728": { "compartment": "compartment_5460", "id": "reaction_10089728", "reactome": "R-BTA-9011595", "name": "GSTZ1 dimer dehalogenates DCA to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_113521" ], "products": [ "species_904849", "species_3301973" ], "modifiers": [ [ "species_10089725", "catalyst" ], [ "species_1655887", "catalyst" ], [ "species_9010792", "inhibitor" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10076468": { "compartment": "compartment_70101", "id": "reaction_10076468", "reactome": "R-BTA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10076465", "catalyst" ] ], "additional_components": [ "species_29426", "A4FUZ1", "ENSBTAT00000016884" ] }, "reaction_10033671": { "compartment": "compartment_70101", "id": "reaction_10033671", "reactome": "R-BTA-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_29398", "species_73473" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10051980": { "compartment": "compartment_70616", "id": "reaction_10051980", "reactome": "R-BTA-880050", "name": "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_880013" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051977", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020226" ] }, "reaction_10051973": { "compartment": "compartment_5460", "id": "reaction_10051973", "reactome": "R-BTA-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051970", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_880067", "catalyst" ], [ "species_113527", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081426" ] }, "reaction_10033868": { "compartment": "compartment_5460", "id": "reaction_10033868", "reactome": "R-BTA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10033865", "catalyst" ] ], "additional_components": [ "Q29RK1", "ENSBTAT00000005730" ] }, "reaction_10050446": { "compartment": "compartment_5460", "id": "reaction_10050446", "reactome": "R-BTA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10050443", "catalyst" ] ], "additional_components": [ "Q04467", "ENSBTAT00000018741", "species_113527" ] }, "reaction_10089808": { "compartment": "compartment_5460", "id": "reaction_10089808", "reactome": "R-BTA-9012349", "name": "ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_113544" ], "products": [ "species_113529", "species_113557", "species_113600", "species_29376" ], "modifiers": [ [ "species_10089805", "catalyst" ] ], "additional_components": [ "species_29926", "Q0VCX7", "ENSBTAT00000000306" ] }, "reaction_10089795": { "compartment": "compartment_5460", "id": "reaction_10089795", "reactome": "R-BTA-9012268", "name": "ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544", "species_113526" ], "products": [ "species_113529", "species_113557", "species_29362", "species_29376" ], "modifiers": [ [ "species_10089792", "catalyst" ], [ "species_113588", "catalyst" ], [ "species_113593", "inhibitor" ] ], "additional_components": [ "A0A3Q1MWG7", "ENSBTAT00000074198", "species_29926" ] }, "reaction_10050437": { "compartment": "compartment_5462", "id": "reaction_10050437", "reactome": "R-BTA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10050434", "catalyst" ] ], "additional_components": [ "P11024", "ENSBTAT00000080867" ] }, "reaction_10089782": { "compartment": "compartment_5460", "id": "reaction_10089782", "reactome": "R-BTA-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_113557", "species_29376" ], "modifiers": [ [ "species_10089779", "catalyst" ] ], "additional_components": [ "Q2HJ98", "ENSBTAT00000046873", "species_29926" ] }, "reaction_10073835": { "compartment": "compartment_17938", "id": "reaction_10073835", "reactome": "R-BTA-5672017", "name": "Rheb in the MTORC1 complex hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10074507": { "compartment": "compartment_5683628", "id": "reaction_10074507", "reactome": "R-BTA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074495" ], "products": [ "species_10074505" ], "modifiers": [ [ "species_10052773", "catalyst" ] ], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "species_1602375", "species_1602375", "O41515", "ENSBTAT00000015449", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10074365": { "compartment": "compartment_70101", "id": "reaction_10074365", "reactome": "R-BTA-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10074362", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10074381": { "compartment": "compartment_70101", "id": "reaction_10074381", "reactome": "R-BTA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074371", "species_10074377" ], "products": [ "species_10074379" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074415": { "compartment": "compartment_70101", "id": "reaction_10074415", "reactome": "R-BTA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074399", "species_10074377" ], "products": [ "species_10074413" ], "modifiers": [], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449" ] }, "reaction_10074142": { "compartment": "compartment_70101", "id": "reaction_10074142", "reactome": "R-BTA-5673768", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073828", "species_113592" ], "products": [ "species_29370", "species_10074140" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10074302": { "compartment": "compartment_70101", "id": "reaction_10074302", "reactome": "R-BTA-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693050", "species_10074298" ], "products": [ "species_10074300" ], "modifiers": [], "additional_components": [ "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "species_5693050" ] }, "reaction_10090398": { "compartment": "compartment_70101", "id": "reaction_10090398", "reactome": "R-BTA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074379" ], "products": [ "species_10074653" ], "modifiers": [], "additional_components": [ "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074659": { "compartment": "compartment_70101", "id": "reaction_10074659", "reactome": "R-BTA-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074655", "species_10074653" ], "products": [ "species_10074657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083652", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A4FUE9", "ENSBTAT00000083652" ] }, "reaction_10070265": { "compartment": "compartment_17927", "id": "reaction_10070265", "reactome": "R-BTA-5205681", "name": "Pink1 is cleaved on healthy mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070263" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10070218": { "compartment": "compartment_70101", "id": "reaction_10070218", "reactome": "R-BTA-5205649", "name": "p62 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10070210" ], "products": [ "species_10070216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "O41515", "ENSBTAT00000015449" ] }, "reaction_10070259": { "compartment": "compartment_70101", "id": "reaction_10070259", "reactome": "R-BTA-5205661", "name": "Pink1 is recruited from the cytoplasm to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070224" ], "products": [ "species_10070226" ], "modifiers": [ [ "species_10070256", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455", "A6QPI6", "ENSBTAT00000013405", "Q2KI08", "ENSBTAT00000070920", "Q1LZB5", "ENSBTAT00000032251", "Q08E34", "ENSBTAT00000019001", "A8YXZ8", "ENSBTAT00000046547", "A6H7B1", "ENSBTAT00000000733", "Q56JY4", "ENSBTAT00000011817" ] }, "reaction_10070261": { "compartment": "compartment_17906", "id": "reaction_10070261", "reactome": "R-BTA-5205672", "name": "Uncleaved Pink1 accumulates in damaged mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10088891": { "compartment": "compartment_70101", "id": "reaction_10088891", "reactome": "R-BTA-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10087624" ], "products": [ "species_10088889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "ENSBTAT00000002144", "F1N5S9", "ENSBTAT00000002144", "O41515", "ENSBTAT00000015449" ] }, "reaction_10087615": { "compartment": "compartment_70101", "id": "reaction_10087615", "reactome": "R-BTA-8948139", "name": "p-S13-FUNDC1 is dephosphorylated by PGAM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087608" ], "products": [ "species_10087605" ], "modifiers": [ [ "species_10087612", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000009887" ] }, "reaction_10087621": { "compartment": "compartment_70101", "id": "reaction_10087621", "reactome": "R-BTA-8948143", "name": "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087608" ], "products": [ "species_10087618", "species_29370" ], "modifiers": [ [ "species_10040957", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000011767" ] }, "reaction_10073831": { "compartment": "compartment_17938", "id": "reaction_10073831", "reactome": "R-BTA-5672010", "name": "Active MTORC1 phosphorylates ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073822" ], "products": [ "species_10073828", "species_29370" ], "modifiers": [ [ "species_10073822", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10050514": { "compartment": "compartment_876", "id": "reaction_10050514", "reactome": "R-BTA-451283", "name": "kainate receptor binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10050510" ], "products": [ "species_10050512" ], "modifiers": [], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10050517": { "compartment": "compartment_70101", "id": "reaction_10050517", "reactome": "R-BTA-451311", "name": "Activation of Ca-permeable Kainate receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10050512", "catalyst" ] ], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10045419": { "compartment": "compartment_876", "id": "reaction_10045419", "reactome": "R-BTA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10045421": { "compartment": "compartment_70101", "id": "reaction_10045421", "reactome": "R-BTA-374909", "name": "Metabolism of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209789", "species_29356", "species_29368" ], "products": [ "species_5279533", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10039481": { "compartment": "compartment_70101", "id": "reaction_10039481", "reactome": "R-BTA-166869", "name": "TRAF6 binds MEKK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10039469" ], "products": [ "species_10039475" ], "modifiers": [ [ "species_10039479", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021630", "ENSBTAT00000018325", "E1B847", "ENSBTAT00000018325", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000020029" ] }, "reaction_10050256": { "compartment": "compartment_70101", "id": "reaction_10050256", "reactome": "R-BTA-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039518" ], "products": [ "species_10039505" ], "modifiers": [], "additional_components": [ "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10042826": { "compartment": "compartment_7660", "id": "reaction_10042826", "reactome": "R-BTA-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10042823", "catalyst" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "F1N1S8", "ENSBTAT00000007277" ] }, "reaction_10043488": { "compartment": "compartment_7660", "id": "reaction_10043488", "reactome": "R-BTA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10043479", "catalyst" ], [ "species_10043486", "inhibitor" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "Q2T9T7", "ENSBTAT00000078874", "F1MM08", "ENSBTAT00000061049", "A6QLS1", "ENSBTAT00000029212", "Q2KJ36", "ENSBTAT00000006022", "Q2T9T7", "ENSBTAT00000078874", "Q2YDN8", "ENSBTAT00000007054" ] }, "reaction_10041950": { "compartment": "compartment_7660", "id": "reaction_10041950", "reactome": "R-BTA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10041927" ], "products": [ "species_113582", "species_10041945" ], "modifiers": [ [ "species_10041947", "catalyst" ] ], "additional_components": [ "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A5PKJ4", "ENSBTAT00000001347" ] }, "reaction_10050208": { "compartment": "compartment_7660", "id": "reaction_10050208", "reactome": "R-BTA-450292", "name": "Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039493", "species_10050204" ], "products": [ "species_10050206" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005660", "O77628", "ENSBTAT00000005660", "Q08DH1", "ENSBTAT00000005279" ] }, "reaction_10039508": { "compartment": "compartment_7660", "id": "reaction_10039508", "reactome": "R-BTA-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10039489" ], "products": [ "species_113582", "species_10039493" ], "modifiers": [ [ "species_10039505", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005279", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10050218": { "compartment": "compartment_70101", "id": "reaction_10050218", "reactome": "R-BTA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050214" ], "products": [ "species_10050216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307" ] }, "reaction_10050254": { "compartment": "compartment_70101", "id": "reaction_10050254", "reactome": "R-BTA-450346", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10050251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LT51", "ENSBTAT00000068866", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176" ] }, "reaction_10050192": { "compartment": "compartment_7660", "id": "reaction_10050192", "reactome": "R-BTA-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050185" ], "products": [ "species_113582", "species_10050189" ], "modifiers": [ [ "species_10050185", "catalyst" ] ], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050196": { "compartment": "compartment_70101", "id": "reaction_10050196", "reactome": "R-BTA-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050189" ], "products": [ "species_10050194" ], "modifiers": [], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476" ] }, "reaction_10050231": { "compartment": "compartment_7660", "id": "reaction_10050231", "reactome": "R-BTA-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050228" ], "products": [ "species_113582", "species_10050185" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10069253": { "compartment": "compartment_876", "id": "reaction_10069253", "reactome": "R-BTA-3928651", "name": "NGEF exchanges GTP for GDP on RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069250", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "Q08DA6", "ENSBTAT00000011773" ] }, "reaction_10077455": { "compartment": "compartment_876", "id": "reaction_10077455", "reactome": "R-BTA-6784189", "name": "JAKs bind LIFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077414", "species_10049952" ], "products": [ "species_10077416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709" ] }, "reaction_10077422": { "compartment": "compartment_876", "id": "reaction_10077422", "reactome": "R-BTA-6783524", "name": "OSM,LIF,CTF1 receptor complex binds gp130", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049956", "species_10077418" ], "products": [ "species_10077420" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10077424": { "compartment": "compartment_876", "id": "reaction_10077424", "reactome": "R-BTA-6783552", "name": "OSM binds LIFR:JAKs,OSMR:JAKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077410", "species_10077416" ], "products": [ "species_10077418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515" ] }, "reaction_10065517": { "compartment": "compartment_876", "id": "reaction_10065517", "reactome": "R-BTA-2424480", "name": "PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065514", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "F1MI53", "ENSBTAT00000074586", "A0A3Q1NAW3", "ENSBTAT00000070846", "A0A2Z2AM52", "ENSBTAT00000080723", "A3R3B5", "ENSBTAT00000077363", "A0A3Q1M7L0", "ENSBTAT00000075285", "A8E4Q0", "ENSBTAT00000031648", "A0A3Q1NM98", "ENSBTAT00000071353", "F1MHY4", "ENSBTAT00000006472", "A3R3B4", "ENSBTAT00000077363", "F1MPK9", "ENSBTAT00000055860", "A0A140T8B5", "ENSBTAT00000037859", "A0A3Q1N4Y9", "ENSBTAT00000068807", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0JNB0", "ENSBTAT00000015730", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065491": { "compartment": "compartment_876", "id": "reaction_10065491", "reactome": "R-BTA-2424477", "name": "SOS mediated nucleotide exchange of RAS (SHC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040851": { "compartment": "compartment_12045", "id": "reaction_10040851", "reactome": "R-BTA-190681", "name": "Connexin oligomerization in endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040846" ], "products": [ "species_10040848" ], "modifiers": [ [ "species_10040846", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027331", "O18968", "ENSBTAT00000027331", "ENSBTAT00000027331" ] }, "reaction_10049067": { "compartment": "compartment_114584", "id": "reaction_10049067", "reactome": "R-BTA-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_114565" ], "modifiers": [ [ "species_10049064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013298" ] }, "reaction_10051002": { "compartment": "compartment_984", "id": "reaction_10051002", "reactome": "R-BTA-482770", "name": "Release of platelet secretory granule components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050998" ], "products": [ "species_10051000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "ENSBTAT00000009564" ] }, "reaction_10050924": { "compartment": "compartment_876", "id": "reaction_10050924", "reactome": "R-BTA-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050904" ], "products": [ "species_10050922" ], "modifiers": [], "additional_components": [ "species_29438", "A7E3W2", "ENSBTAT00000001802", "species_29370", "species_29926", "Q29RS5", "ENSBTAT00000084323", "species_113592", "A0A3Q1M5Q6", "ENSBTAT00000076112", "A5PKI3", "ENSBTAT00000073296", "species_29372", "A0A452DIU4", "ENSBTAT00000024391", "species_74016", "A0A3Q1LTE4", "ENSBTAT00000080253", "Q27967", "ENSBTAT00000002631", "species_209914", "species_29420", "species_111294", "A6H754", "ENSBTAT00000022777", "species_74016", "species_29438", "Q27967", "ENSBTAT00000002631", "species_29370", "A6H754", "ENSBTAT00000022777", "species_111294", "A0A452DIU4", "ENSBTAT00000024391", "species_29926", "species_113592", "Q29RS5", "ENSBTAT00000084323", "A0A3Q1LTE4", "ENSBTAT00000080253", "species_209914", "A0A3Q1M5Q6", "ENSBTAT00000076112", "species_29372", "A5PKI3", "ENSBTAT00000073296", "species_29420", "A7E3W2", "ENSBTAT00000001802" ] }, "reaction_10050994": { "compartment": "compartment_876", "id": "reaction_10050994", "reactome": "R-BTA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050980" ], "products": [ "species_10050992" ], "modifiers": [], "additional_components": [ "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "A0A3Q1LI93", "ENSBTAT00000075662", "P26201", "ENSBTAT00000080828", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A5PK28", "ENSBTAT00000067657", "A0A3Q1LEU1", "ENSBTAT00000081148", "A0A3Q1LN74", "ENSBTAT00000074339", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LI93", "ENSBTAT00000075662", "A5PK28", "ENSBTAT00000067657", "P26201", "ENSBTAT00000080828", "A0A3Q1LN74", "ENSBTAT00000074339", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "A0A3Q1LEU1", "ENSBTAT00000081148" ] }, "reaction_10050948": { "compartment": "compartment_876", "id": "reaction_10050948", "reactome": "R-BTA-481010", "name": "Surface deployment of platelet dense granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050938" ], "products": [ "species_10050946" ], "modifiers": [], "additional_components": [ "Q8HZJ5", "ENSBTAT00000078091", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "Q8HZJ5", "ENSBTAT00000078091" ] }, "reaction_10050870": { "compartment": "compartment_876", "id": "reaction_10050870", "reactome": "R-BTA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050802" ], "products": [ "species_10050868" ], "modifiers": [], "additional_components": [ "A0A452DIX0", "ENSBTAT00000026577", "P17697", "ENSBTAT00000007324", "A4IF69", "ENSBTAT00000004806", "F1MY12", "ENSBTAT00000016092", "A0A140T8C8", "ENSBTAT00000053071", "A0A0A0MP92", "ENSBTAT00000011576", "C4PU73", "ENSBTAT00000009718", "A0A0A0MPA0", "ENSBTAT00000038516", "G3N1U4", "ENSBTAT00000064475", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A0A0MP89", "ENSBTAT00000009261", "A0A452DJK6", "ENSBTAT00000064935", "E1BMJ0", "ENSBTAT00000021638", "Q9XS50", "ENSBTAT00000019613", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P28800", "ENSBTAT00000027793", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "A6QP91", "ENSBTAT00000015925", "E1BBY0", "ENSBTAT00000051964", "E1B726", "ENSBTAT00000001674", "A0A452DIJ9", "ENSBTAT00000019232", "G3X7J5", "ENSBTAT00000032623", "F1MD83", "ENSBTAT00000015874", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1M2H1", "ENSBTAT00000067311", "Q17QL4", "ENSBTAT00000007016", "A4IFA6", "ENSBTAT00000007913", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LPG8", "ENSBTAT00000083114", "G5E5W1", "ENSBTAT00000036726", "P12763", "ENSBTAT00000000673", "F1MX05", "ENSBTAT00000004949", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "Q2HJ33", "ENSBTAT00000009160", "P07455", "ENSBTAT00000014713", "A0A452DIJ9", "ENSBTAT00000019232", "P12763", "ENSBTAT00000000673", "Q5GN72", "ENSBTAT00000022991", "P07455", "ENSBTAT00000014713", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "E1BBY0", "ENSBTAT00000051964", "A4IFA6", "ENSBTAT00000007913", "E1BMJ0", "ENSBTAT00000021638", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "P17697", "ENSBTAT00000007324", "F1MY12", "ENSBTAT00000016092", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1M2H1", "ENSBTAT00000067311", "A0A140T8C8", "ENSBTAT00000053071", "E1B726", "ENSBTAT00000001674", "A6QP91", "ENSBTAT00000015925", "A4IF69", "ENSBTAT00000004806", "F1MX05", "ENSBTAT00000004949", "G5E5W1", "ENSBTAT00000036726", "P28800", "ENSBTAT00000027793", "F1MD83", "ENSBTAT00000015874", "Q2HJ33", "ENSBTAT00000009160", "Q17QL4", "ENSBTAT00000007016", "A0A3Q1LPG8", "ENSBTAT00000083114", "G3X7J5", "ENSBTAT00000032623", "Q9XS50", "ENSBTAT00000019613", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A452DIX0", "ENSBTAT00000026577" ] }, "reaction_10051062": { "compartment": "compartment_70101", "id": "reaction_10051062", "reactome": "R-BTA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051036" ], "products": [ "species_10051060" ], "modifiers": [], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "F1MHC2", "ENSBTAT00000012094", "P80513", "ENSBTAT00000045083", "P63258", "ENSBTAT00000008132", "F1MRZ8", "ENSBTAT00000012724", "A0A3Q1MLQ7", "ENSBTAT00000074863", "A7YY77", "ENSBTAT00000034535", "F1MNQ4", "ENSBTAT00000039344", "A0A3Q1LP13", "ENSBTAT00000075491", "E1B8Z0", "ENSBTAT00000079099", "Q5E9F5", "ENSBTAT00000080925", "A0A3Q1MLQ7", "ENSBTAT00000074863", "F1MHC2", "ENSBTAT00000012094", "A7YY77", "ENSBTAT00000034535", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1LP13", "ENSBTAT00000075491", "F1MRZ8", "ENSBTAT00000012724", "Q5E9F5", "ENSBTAT00000080925", "F1MNQ4", "ENSBTAT00000039344", "P80513", "ENSBTAT00000045083", "E1B8Z0", "ENSBTAT00000079099", "P63258", "ENSBTAT00000008132" ] }, "reaction_10090306": { "compartment": "compartment_876", "id": "reaction_10090306", "reactome": "R-BTA-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090272", "species_10090302" ], "products": [ "species_10090304" ], "modifiers": [], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29438", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A5D7J5", "ENSBTAT00000024876", "species_29438" ] }, "reaction_10090311": { "compartment": "compartment_876", "id": "reaction_10090311", "reactome": "R-BTA-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090308" ], "products": [ "species_29420", "species_10090272" ], "modifiers": [ [ "species_10090308", "catalyst" ] ], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29420", "A5D7J5", "ENSBTAT00000024876", "species_29438", "A5D7J5", "ENSBTAT00000024876", "species_29420" ] }, "reaction_10081497": { "compartment": "compartment_70101", "id": "reaction_10081497", "reactome": "R-BTA-6803789", "name": "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6803743" ], "products": [ "species_193473", "species_449701" ], "modifiers": [ [ "species_10081494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074115" ] }, "reaction_10050153": { "compartment": "compartment_70101", "id": "reaction_10050153", "reactome": "R-BTA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10050150", "catalyst" ] ], "additional_components": [ "F1MZY2", "ENSBTAT00000023441", "A0A452DHW0", "ENSBTAT00000002867" ] }, "reaction_10081490": { "compartment": "compartment_70101", "id": "reaction_10081490", "reactome": "R-BTA-6803771", "name": "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803785", "species_113592" ], "products": [ "species_6803738", "species_70106", "species_29370" ], "modifiers": [ [ "species_10081487", "catalyst" ] ], "additional_components": [ "CHEBI:27459", "species_1678743", "species_449703", "species_6803743", "A0A452DJF8", "ENSBTAT00000019528" ] }, "reaction_10049778": { "compartment": "compartment_70101", "id": "reaction_10049778", "reactome": "R-BTA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10049775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086526" ] }, "reaction_10069593": { "compartment": "compartment_70101", "id": "reaction_10069593", "reactome": "R-BTA-4608852", "name": "SMURF1/2 ubiquitinates PRICKLE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069585" ], "products": [ "species_10069588" ], "modifiers": [ [ "species_10069590", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072372", "ENSBTAT00000072372", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069595": { "compartment": "compartment_70101", "id": "reaction_10069595", "reactome": "R-BTA-4608854", "name": "SMURF1/2 are recruited to the DVL2:PARD6A complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069581", "species_10042973" ], "products": [ "species_10069590" ], "modifiers": [], "additional_components": [ "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000043725", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069872": { "compartment": "compartment_876", "id": "reaction_10069872", "reactome": "R-BTA-5099886", "name": "WNT5A binding to FZD promotes PRICKLE1 degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069868", "species_10067196" ], "products": [ "species_10069870" ], "modifiers": [], "additional_components": [ "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10044480": { "compartment": "compartment_17960", "id": "reaction_10044480", "reactome": "R-BTA-215526", "name": "CYP4F3 20-hydroxylates LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215557", "species_113601" ], "products": [ "species_113519", "species_113564", "species_571314" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10071909": { "compartment": "compartment_12045", "id": "reaction_10071909", "reactome": "R-BTA-5602295", "name": "CYP4F22 20-hydroxylates TrXA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2142713", "species_29368", "species_29364" ], "products": [ "species_5602281", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066325" ] }, "reaction_10044151": { "compartment": "compartment_12045", "id": "reaction_10044151", "reactome": "R-BTA-211873", "name": "CYP4F2, 4F3 20-hydroxylate LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266056", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2161636" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10073037": { "compartment": "compartment_876", "id": "reaction_10073037", "reactome": "R-BTA-5654423", "name": "Activated FGFR4:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073033" ], "products": [ "species_10073035" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073041": { "compartment": "compartment_70101", "id": "reaction_10073041", "reactome": "R-BTA-5654425", "name": "Activated FGFR4 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065241" ], "products": [ "species_10073039" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073044": { "compartment": "compartment_70101", "id": "reaction_10073044", "reactome": "R-BTA-5654426", "name": "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073047": { "compartment": "compartment_70101", "id": "reaction_10073047", "reactome": "R-BTA-5654428", "name": "Activated FGFR4 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073039" ], "products": [ "species_29370", "species_10073033" ], "modifiers": [ [ "species_10073039", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10076847": { "compartment": "compartment_12045", "id": "reaction_10076847", "reactome": "R-BTA-5696119", "name": "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_5696122", "species_29368" ], "products": [ "species_29356", "species_1497857", "species_76116", "species_5696116" ], "modifiers": [ [ "species_10076844", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069764" ] }, "reaction_10035838": { "compartment": "compartment_70101", "id": "reaction_10035838", "reactome": "R-BTA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10035795": { "compartment": "compartment_70101", "id": "reaction_10035795", "reactome": "R-BTA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10035790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030932" ] }, "reaction_10035829": { "compartment": "compartment_70101", "id": "reaction_10035829", "reactome": "R-BTA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10035826", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LV95", "ENSBTAT00000067199" ] }, "reaction_10080887": { "compartment": "compartment_12045", "id": "reaction_10080887", "reactome": "R-BTA-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76103", "species_76194" ], "modifiers": [ [ "species_10080884", "catalyst" ] ], "additional_components": [ "Q70VZ7", "ENSBTAT00000011091", "F1MLQ3", "ENSBTAT00000010395", "G3MYF6", "ENSBTAT00000064201" ] }, "reaction_10090409": { "compartment": "compartment_7660", "id": "reaction_10090409", "reactome": "R-BTA-9021357", "name": "PRKCI phosphorylates ELF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10090404" ], "products": [ "species_113582", "species_10090404" ], "modifiers": [ [ "species_10090406", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011536", "ENSBTAT00000011536", "ENSBTAT00000061563" ] }, "reaction_10044826": { "compartment": "compartment_70101", "id": "reaction_10044826", "reactome": "R-BTA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10044815" ], "products": [ "species_29420", "species_10044819" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "P84080", "ENSBTAT00000010159", "species_29420", "P84080", "ENSBTAT00000010159", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10045538": { "compartment": "compartment_70101", "id": "reaction_10045538", "reactome": "R-BTA-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10045525", "species_10045531" ], "products": [ "species_10045527", "species_10045525", "species_10045533" ], "modifiers": [ [ "species_10045535", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10034921": { "compartment": "compartment_70101", "id": "reaction_10034921", "reactome": "R-BTA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034924": { "compartment": "compartment_70101", "id": "reaction_10034924", "reactome": "R-BTA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034927": { "compartment": "compartment_70101", "id": "reaction_10034927", "reactome": "R-BTA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10048761": { "compartment": "compartment_876", "id": "reaction_10048761", "reactome": "R-BTA-427656", "name": "SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048758", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084837" ] }, "reaction_10048754": { "compartment": "compartment_876", "id": "reaction_10048754", "reactome": "R-BTA-427645", "name": "SLC34A3 cotransports Pi, 2Na+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069253" ] }, "reaction_10065819": { "compartment": "compartment_984", "id": "reaction_10065819", "reactome": "R-BTA-2534248", "name": "DCN (decorin) degradation by MMP2, MMP3, MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065294" ], "products": [ "species_10065814", "species_10065812" ], "modifiers": [ [ "species_10065816", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004562", "ENSBTAT00000004562", "ENSBTAT00000004562", "F1MU56", "ENSBTAT00000006029", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059674": { "compartment": "compartment_984", "id": "reaction_10059674", "reactome": "R-BTA-1566962", "name": "Elastin degradation by elastin-degrading extracellular proteinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059657" ], "products": [ "species_10059665" ], "modifiers": [ [ "species_10059671", "catalyst" ] ], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTX6", "ENSBTAT00000013124", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10087324": { "compartment": "compartment_984", "id": "reaction_10087324", "reactome": "R-BTA-8940561", "name": "MMP7 cleaves OPTC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087311" ], "products": [ "species_10087319", "species_10087317", "species_10087315", "species_10087321" ], "modifiers": [ [ "species_10058184", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000006029" ] }, "reaction_10064649": { "compartment": "compartment_876", "id": "reaction_10064649", "reactome": "R-BTA-2167942", "name": "Collagen type XIII ectodomain shedding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064303" ], "products": [ "species_10064625", "species_10064623" ], "modifiers": [], "additional_components": [ "F6RND5", "ENSBTAT00000039811", "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10076984": { "compartment": "compartment_5460", "id": "reaction_10076984", "reactome": "R-BTA-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696409", "species_113521" ], "products": [ "species_113548", "species_5693978", "species_113556" ], "modifiers": [ [ "species_10076981", "catalyst" ] ], "additional_components": [ "E1B8R9", "ENSBTAT00000018115" ] }, "reaction_10059533": { "compartment": "compartment_984", "id": "reaction_10059533", "reactome": "R-BTA-1564142", "name": "Collagen type IV degradation by MMP2,3,4,9,10,12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526" ], "products": [ "species_10058166" ], "modifiers": [ [ "species_10059530", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059598": { "compartment": "compartment_984", "id": "reaction_10059598", "reactome": "R-BTA-1564164", "name": "Collagen type V degradation by MMP2,9,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058699" ], "products": [ "species_10059595" ], "modifiers": [ [ "species_10059528", "catalyst" ] ], "additional_components": [ "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "ENSBTAT00000013124" ] }, "reaction_10058561": { "compartment": "compartment_984", "id": "reaction_10058561", "reactome": "R-BTA-1474197", "name": "Collagen type II degradation by MMP1,3,8,13,PRSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058552" ], "products": [ "species_10057938" ], "modifiers": [ [ "species_10058558", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059441": { "compartment": "compartment_984", "id": "reaction_10059441", "reactome": "R-BTA-1564112", "name": "Collagen type VI degradation by MMP2,9,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282" ], "products": [ "species_10059434" ], "modifiers": [ [ "species_10059438", "catalyst" ] ], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000008025" ] }, "reaction_10064705": { "compartment": "compartment_984", "id": "reaction_10064705", "reactome": "R-BTA-2168038", "name": "Collagen type XV restin release", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064651" ], "products": [ "species_10064677", "species_10064703" ], "modifiers": [], "additional_components": [ "A0A3Q1M0N0", "ENSBTAT00000072268", "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10058193": { "compartment": "compartment_984", "id": "reaction_10058193", "reactome": "R-BTA-1454757", "name": "Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058168" ], "products": [], "modifiers": [ [ "species_10058190", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059651": { "compartment": "compartment_984", "id": "reaction_10059651", "reactome": "R-BTA-1564169", "name": "Collagen type VIII degradation by MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059648" ], "products": [ "species_10058052" ], "modifiers": [ [ "species_10058172", "catalyst" ] ], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "ENSBTAT00000021014" ] }, "reaction_10059689": { "compartment": "compartment_984", "id": "reaction_10059689", "reactome": "R-BTA-1592297", "name": "Full activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059684" ], "products": [ "species_10058172" ], "modifiers": [ [ "species_10059686", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "F1MU56", "ENSBTAT00000006029", "F1MMD4", "ENSBTAT00000008025", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059913": { "compartment": "compartment_984", "id": "reaction_10059913", "reactome": "R-BTA-1604712", "name": "Initial activation of proMMP7 by trypsin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059908", "species_10059906" ], "modifiers": [ [ "species_10059910", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "A7YWU9", "ENSBTAT00000028731" ] }, "reaction_10059787": { "compartment": "compartment_984", "id": "reaction_10059787", "reactome": "R-BTA-1592371", "name": "Initial activation of proMMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059746" ], "products": [ "species_10059750", "species_10059748" ], "modifiers": [ [ "species_10059784", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A7YWU6", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059869": { "compartment": "compartment_984", "id": "reaction_10059869", "reactome": "R-BTA-1602458", "name": "Activation of proMMP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059862" ], "products": [ "species_10059528" ], "modifiers": [ [ "species_10059866", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059804": { "compartment": "compartment_984", "id": "reaction_10059804", "reactome": "R-BTA-1592398", "name": "Activation of proMMP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059793" ], "products": [ "species_10058188" ], "modifiers": [ [ "species_10059801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063400", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "Q6H320", "ENSBTAT00000024677", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10059902": { "compartment": "compartment_984", "id": "reaction_10059902", "reactome": "R-BTA-1602473", "name": "Autocatalytic activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059706" ], "products": [ "species_10059684", "species_10059899" ], "modifiers": [ [ "species_10059706", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014" ] }, "reaction_10059918": { "compartment": "compartment_984", "id": "reaction_10059918", "reactome": "R-BTA-1604731", "name": "Autocatalytic activation of MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059748" ], "products": [ "species_10058180", "species_10059915" ], "modifiers": [ [ "species_10059748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124" ] }, "reaction_10059744": { "compartment": "compartment_984", "id": "reaction_10059744", "reactome": "R-BTA-1592362", "name": "Activation of proMMP7 by MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059735", "species_10058184" ], "modifiers": [ [ "species_10059741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "P25975", "ENSBTAT00000036427", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059731": { "compartment": "compartment_984", "id": "reaction_10059731", "reactome": "R-BTA-1592316", "name": "Initial activation of proMMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059704" ], "products": [ "species_10059708", "species_10059706" ], "modifiers": [ [ "species_10059728", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "A6QPI9", "ENSBTAT00000009636", "E1BAD2", "ENSBTAT00000054741", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674", "E1B8U1", "ENSBTAT00000052512", "E1BIP7", "ENSBTAT00000011737" ] }, "reaction_10059923": { "compartment": "compartment_984", "id": "reaction_10059923", "reactome": "R-BTA-1604763", "name": "Autocatalytic activation of MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059906" ], "products": [ "species_10059920", "species_10058184" ], "modifiers": [ [ "species_10059906", "catalyst" ], [ "species_1604783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "CHEBI:24505", "species_444761" ] }, "reaction_10060003": { "compartment": "compartment_17963", "id": "reaction_10060003", "reactome": "R-BTA-1605825", "name": "MT-MMPs are sorted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059897" ], "products": [ "species_10060001" ], "modifiers": [], "additional_components": [ "F1N797", "ENSBTAT00000061368", "F1N797", "ENSBTAT00000061368" ] }, "reaction_10068885": { "compartment": "compartment_984", "id": "reaction_10068885", "reactome": "R-BTA-3814820", "name": "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10068874", "species_10068872" ], "modifiers": [ [ "species_10068882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MF35", "ENSBTAT00000015593", "E1BEV7", "ENSBTAT00000001218", "A0A452DK38", "ENSBTAT00000036427", "F1N0X6", "ENSBTAT00000007834" ] }, "reaction_10065751": { "compartment": "compartment_984", "id": "reaction_10065751", "reactome": "R-BTA-2485148", "name": "Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063837" ], "products": [ "species_10065748" ], "modifiers": [ [ "species_10058176", "catalyst" ] ], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "ENSBTAT00000081947" ] }, "reaction_10087543": { "compartment": "compartment_876", "id": "reaction_10087543", "reactome": "R-BTA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087535" ], "products": [ "species_10087541" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068477", "A0A3Q1MG91", "ENSBTAT00000068477" ] }, "reaction_10059702": { "compartment": "compartment_984", "id": "reaction_10059702", "reactome": "R-BTA-1592314", "name": "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10059697", "species_10059695" ], "modifiers": [ [ "species_10059699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MTX6", "ENSBTAT00000013124", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10061174": { "compartment": "compartment_876", "id": "reaction_10061174", "reactome": "R-BTA-1861621", "name": "Cross-linking of FCGRIIA with IgG-coated Ag", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061170", "species_10039426" ], "products": [ "species_10061172" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029116", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1MHH9", "ENSBTAT00000029116" ] }, "reaction_10033690": { "compartment": "compartment_5460", "id": "reaction_10033690", "reactome": "R-BTA-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113552" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10033687", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021616" ] }, "reaction_10033706": { "compartment": "compartment_70101", "id": "reaction_10033706", "reactome": "R-BTA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10033703", "catalyst" ] ], "additional_components": [ "species_113527", "Q2KJ64", "ENSBTAT00000016461" ] }, "reaction_10033770": { "compartment": "compartment_70101", "id": "reaction_10033770", "reactome": "R-BTA-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113567", "species_29498" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10033767", "catalyst" ] ], "additional_components": [ "Q2KHW4", "ENSBTAT00000015468", "A0A3Q1N1S4", "ENSBTAT00000015847" ] }, "reaction_10033697": { "compartment": "compartment_5460", "id": "reaction_10033697", "reactome": "R-BTA-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113561", "species_29896" ], "products": [ "species_113548", "species_113581", "species_29676" ], "modifiers": [ [ "species_10033694", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022158" ] }, "reaction_10084008": { "compartment": "compartment_70101", "id": "reaction_10084008", "reactome": "R-BTA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083994", "species_10083992" ], "products": [ "species_10084006", "species_10083996" ], "modifiers": [], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1ME38", "ENSBTAT00000008985", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "F1ME38", "ENSBTAT00000008985", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088" ] }, "reaction_10084122": { "compartment": "compartment_70101", "id": "reaction_10084122", "reactome": "R-BTA-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084119" ], "products": [ "species_10033406", "species_10033404", "species_10033402" ], "modifiers": [ [ "species_10075812", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000026356" ] }, "reaction_10084113": { "compartment": "compartment_70101", "id": "reaction_10084113", "reactome": "R-BTA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033394" ], "products": [ "species_10033394", "species_10034499" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087088", "ENSBTAT00000087088", "ENSBTAT00000087088", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10084117": { "compartment": "compartment_70101", "id": "reaction_10084117", "reactome": "R-BTA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084115" ], "products": [ "species_10033398", "species_10034743" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010176", "ENSBTAT00000010176", "ENSBTAT00000010176", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10086702": { "compartment": "compartment_459", "id": "reaction_10086702", "reactome": "R-BTA-8939323", "name": "RNF181 binds BCL10 and Ubiquitin:E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086688", "species_10086698", "species_10043291" ], "products": [ "species_10086700" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10086710": { "compartment": "compartment_459", "id": "reaction_10086710", "reactome": "R-BTA-8939335", "name": "RNF181 polyubiquinates BCL10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086700", "species_10086698" ], "products": [ "species_10086707", "species_10086688", "species_10086705" ], "modifiers": [ [ "species_10086700", "catalyst" ] ], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1MAR8", "ENSBTAT00000084854", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "ENSBTAT00000024336", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10047210": { "compartment": "compartment_984", "id": "reaction_10047210", "reactome": "R-BTA-390649", "name": "CHRM1,3,5 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045758", "species_372533" ], "products": [ "species_10045760" ], "modifiers": [], "additional_components": [ "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383" ] }, "reaction_10047214": { "compartment": "compartment_984", "id": "reaction_10047214", "reactome": "R-BTA-390673", "name": "CHRM2,4 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046209", "species_372533" ], "products": [ "species_10046211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019534", "species_372533", "P41985", "ENSBTAT00000019534" ] }, "reaction_10047224": { "compartment": "compartment_984", "id": "reaction_10047224", "reactome": "R-BTA-390846", "name": "D2D3,4 bind to DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10046197" ], "products": [ "species_10046199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002768", "species_159362", "F1N454", "ENSBTAT00000002768" ] }, "reaction_10091556": { "compartment": "compartment_984", "id": "reaction_10091556", "reactome": "R-BTA-9656244", "name": "DRD2 binds DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10091552" ], "products": [ "species_10091554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014422", "F1N4I3", "ENSBTAT00000014422", "species_159362" ] }, "reaction_10047222": { "compartment": "compartment_984", "id": "reaction_10047222", "reactome": "R-BTA-390835", "name": "DRD1,5 bind DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10047218" ], "products": [ "species_10047220" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062955", "Q95136", "ENSBTAT00000062955", "species_159362" ] }, "reaction_10091929": { "compartment": "compartment_984", "id": "reaction_10091929", "reactome": "R-BTA-9693347", "name": "HTR1A binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091925", "species_114523" ], "products": [ "species_10091927" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054712", "species_209914", "F6Q2H9", "ENSBTAT00000054712" ] }, "reaction_10047256": { "compartment": "compartment_984", "id": "reaction_10047256", "reactome": "R-BTA-390931", "name": "5-HT4, 6 and 7 receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047252", "species_114523" ], "products": [ "species_10047254" ], "modifiers": [], "additional_components": [ "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575", "species_209914", "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10047236": { "compartment": "compartment_984", "id": "reaction_10047236", "reactome": "R-BTA-390929", "name": "HTR1 and 5A receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114523", "species_10046185" ], "products": [ "species_10046187" ], "modifiers": [], "additional_components": [ "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914" ] }, "reaction_10047238": { "compartment": "compartment_984", "id": "reaction_10047238", "reactome": "R-BTA-390930", "name": "5-HT2 receptor can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045782", "species_114523" ], "products": [ "species_10045784" ], "modifiers": [], "additional_components": [ "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796" ] }, "reaction_10047226": { "compartment": "compartment_984", "id": "reaction_10047226", "reactome": "R-BTA-390886", "name": "HRH4 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046191", "species_390899" ], "products": [ "species_10046193" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048201", "species_390899", "E1BBS2", "ENSBTAT00000048201" ] }, "reaction_10091825": { "compartment": "compartment_984", "id": "reaction_10091825", "reactome": "R-BTA-9692880", "name": "HRH3 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390899", "species_10091821" ], "products": [ "species_10091823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020802", "F1MML8", "ENSBTAT00000020802", "species_390899" ] }, "reaction_10047234": { "compartment": "compartment_984", "id": "reaction_10047234", "reactome": "R-BTA-390909", "name": "HRH2 binds hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047230", "species_390899" ], "products": [ "species_10047232" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061359", "species_390899", "E1BK27", "ENSBTAT00000061359" ] }, "reaction_10090968": { "compartment": "compartment_984", "id": "reaction_10090968", "reactome": "R-BTA-9611852", "name": "ADRB3 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051599" ], "products": [ "species_10051601" ], "modifiers": [ [ "species_10090958", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000085511", "CHEBI:28918", "species_209789", "A0A3Q1MQZ8", "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090925": { "compartment": "compartment_984", "id": "reaction_10090925", "reactome": "R-BTA-9609310", "name": "-blockers bind ADRB1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9609307", "species_10090921" ], "products": [ "species_10090923" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047212": { "compartment": "compartment_984", "id": "reaction_10047212", "reactome": "R-BTA-390663", "name": "ADRA2A,B,C bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10090960": { "compartment": "compartment_984", "id": "reaction_10090960", "reactome": "R-BTA-9611839", "name": "3-agonists bind ADRB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611836", "species_10051599" ], "products": [ "species_10090958" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090964": { "compartment": "compartment_984", "id": "reaction_10090964", "reactome": "R-BTA-9611851", "name": "ADRB2 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051593" ], "products": [ "species_10051595" ], "modifiers": [ [ "species_10090962", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047206": { "compartment": "compartment_984", "id": "reaction_10047206", "reactome": "R-BTA-390641", "name": "ADRA1A,B,D bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10045770" ], "products": [ "species_10045772" ], "modifiers": [ [ "species_10047204", "catalyst" ], [ "species_10047202", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443" ] }, "reaction_10047332": { "compartment": "compartment_984", "id": "reaction_10047332", "reactome": "R-BTA-391211", "name": "Trace amine-associated receptors can bind trace amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047328", "species_391200" ], "products": [ "species_10047330" ], "modifiers": [], "additional_components": [ "F1N0G5", "ENSBTAT00000054907", "species_391200", "F1N0G5", "ENSBTAT00000054907" ] }, "reaction_10083878": { "compartment": "compartment_876", "id": "reaction_10083878", "reactome": "R-BTA-8851298", "name": "GPR143 binds L-Dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851314", "species_10046122" ], "products": [ "species_10046124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008485", "G5E581", "ENSBTAT00000008485", "species_8851314" ] }, "reaction_10038450": { "compartment": "compartment_70101", "id": "reaction_10038450", "reactome": "R-BTA-162425", "name": "p-S295-PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10038447", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10036570": { "compartment": "compartment_70101", "id": "reaction_10036570", "reactome": "R-BTA-109699", "name": "PI3K-containing complexes phosphorylate PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10036567", "catalyst" ] ], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "G3XGD3", "ENSBTAT00000029946", "E1BHC1", "ENSBTAT00000016675", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LRU7", "ENSBTAT00000072473", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1M3Q3", "ENSBTAT00000073054", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10036607": { "compartment": "compartment_70101", "id": "reaction_10036607", "reactome": "R-BTA-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10036588" ], "products": [ "species_29370", "species_10036604" ], "modifiers": [ [ "species_10036596", "catalyst" ] ], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036590": { "compartment": "compartment_876", "id": "reaction_10036590", "reactome": "R-BTA-109700", "name": "AKT2 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036586" ], "products": [ "species_10036580", "species_10036588" ], "modifiers": [], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838" ] }, "reaction_10036598": { "compartment": "compartment_876", "id": "reaction_10036598", "reactome": "R-BTA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036594" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10035507": { "compartment": "compartment_70101", "id": "reaction_10035507", "reactome": "R-BTA-74736", "name": "GRB2-1:SOS1 binds p-IRS1,p-IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035503" ], "products": [ "species_10035505" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10035527": { "compartment": "compartment_70101", "id": "reaction_10035527", "reactome": "R-BTA-74737", "name": "p-Y-IRS1,p-Y-IRS2 bind PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10035503" ], "products": [ "species_10035525" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10055817": { "compartment": "compartment_12045", "id": "reaction_10055817", "reactome": "R-BTA-983424", "name": "Budding of COPII coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055815" ], "products": [ "species_10055805" ], "modifiers": [], "additional_components": [ "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10043659": { "compartment": "compartment_12045", "id": "reaction_10043659", "reactome": "R-BTA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580" ], "products": [ "species_10043657" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055819": { "compartment": "compartment_12045", "id": "reaction_10055819", "reactome": "R-BTA-983426", "name": "Capturing cargo and formation of prebudding complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054858", "species_10043657" ], "products": [ "species_10055813" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055821": { "compartment": "compartment_876", "id": "reaction_10055821", "reactome": "R-BTA-983427", "name": "Expression of peptide bound class I MHC on cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055781" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10087807": { "compartment": "compartment_453088", "id": "reaction_10087807", "reactome": "R-BTA-8951499", "name": "Loading of antigenic peptides on to class I MHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055472", "species_983033" ], "products": [ "species_10055474" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "species_1236727", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10054866": { "compartment": "compartment_453088", "id": "reaction_10054866", "reactome": "R-BTA-983138", "name": "Transport of MHC heterotrimer to ER exit site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054864" ], "products": [ "species_10054862", "species_10054858" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q5E9F1", "ENSBTAT00000068015", "Q5E9F1", "ENSBTAT00000068015", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727" ] }, "reaction_10055444": { "compartment": "compartment_17957", "id": "reaction_10055444", "reactome": "R-BTA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10055441", "catalyst" ] ], "additional_components": [ "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10055460": { "compartment": "compartment_17957", "id": "reaction_10055460", "reactome": "R-BTA-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_8943716", "species_983033" ], "modifiers": [ [ "species_10055457", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078466" ] }, "reaction_10055783": { "compartment": "compartment_13945", "id": "reaction_10055783", "reactome": "R-BTA-983421", "name": "Journey of cargo through Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055715" ], "products": [ "species_10055781" ], "modifiers": [], "additional_components": [ "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10039485": { "compartment": "compartment_947587", "id": "reaction_10039485", "reactome": "R-BTA-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10036954" ], "products": [ "species_29438", "species_10037043" ], "modifiers": [ [ "species_10036952", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160" ] }, "reaction_10037641": { "compartment": "compartment_70101", "id": "reaction_10037641", "reactome": "R-BTA-139898", "name": "Caspase-8 activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037731": { "compartment": "compartment_70101", "id": "reaction_10037731", "reactome": "R-BTA-139920", "name": "Translocation of tBID to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037729" ], "products": [ "species_10037269" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737" ] }, "reaction_10037618": { "compartment": "compartment_70101", "id": "reaction_10037618", "reactome": "R-BTA-139893", "name": "Granzyme-B activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000013262" ] }, "reaction_10038007": { "compartment": "compartment_70101", "id": "reaction_10038007", "reactome": "R-BTA-141367", "name": "Myristoylation of tBID by NMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037611" ], "products": [ "species_10037729" ], "modifiers": [ [ "species_10038004", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000007950" ] }, "reaction_10049615": { "compartment": "compartment_984", "id": "reaction_10049615", "reactome": "R-BTA-444171", "name": "Receptor FFAR2 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046048", "species_444210" ], "products": [ "species_10046050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008619", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJV9", "ENSBTAT00000008619" ] }, "reaction_10049617": { "compartment": "compartment_984", "id": "reaction_10049617", "reactome": "R-BTA-444202", "name": "Receptor FFAR1 binds free fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10049585": { "compartment": "compartment_984", "id": "reaction_10049585", "reactome": "R-BTA-444047", "name": "Receptor FFAR3 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046054", "species_444074" ], "products": [ "species_10046056" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053502", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502" ] }, "reaction_10067360": { "compartment": "compartment_876", "id": "reaction_10067360", "reactome": "R-BTA-3296304", "name": "GPR31 is a receptor for 12(S)-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296298", "species_10046489" ], "products": [ "species_10046491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019274", "F1N1J4", "ENSBTAT00000019274", "species_3296298" ] }, "reaction_10041453": { "compartment": "compartment_984", "id": "reaction_10041453", "reactome": "R-BTA-194308", "name": "VEGF-C,D bind to VEGFR3 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041447", "species_10041443" ], "products": [ "species_10041451" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613", "F1MHP5", "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10041463": { "compartment": "compartment_984", "id": "reaction_10041463", "reactome": "R-BTA-194310", "name": "VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041443", "species_10041457" ], "products": [ "species_10041461" ], "modifiers": [], "additional_components": [ "Q9XS50", "ENSBTAT00000019613", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10040328": { "compartment": "compartment_70101", "id": "reaction_10040328", "reactome": "R-BTA-177944", "name": "Activation of SHP2 through the binding to phospho-Gab1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10040245" ], "products": [ "species_10040247" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040299": { "compartment": "compartment_70101", "id": "reaction_10040299", "reactome": "R-BTA-177935", "name": "SHP2 dephosphorylates Tyr 992 on EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040297" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040267": { "compartment": "compartment_70101", "id": "reaction_10040267", "reactome": "R-BTA-177926", "name": "Dephosphorylation of PAG by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040263", "species_29356" ], "products": [ "species_29372", "species_10040265" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067689", "ENSBTAT00000067689", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040254": { "compartment": "compartment_70101", "id": "reaction_10040254", "reactome": "R-BTA-177924", "name": "Dephosphorylation of Gab1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040251" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040277": { "compartment": "compartment_70101", "id": "reaction_10040277", "reactome": "R-BTA-177930", "name": "GAB1 phosphorylation by EGFR kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040271" ], "products": [ "species_10040245", "species_29370" ], "modifiers": [ [ "species_10040271", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10043129": { "compartment": "compartment_876", "id": "reaction_10043129", "reactome": "R-BTA-201677", "name": "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043120", "species_113592" ], "products": [ "species_10043126", "species_29370" ], "modifiers": [ [ "species_10043120", "catalyst" ] ], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1N1K8", "ENSBTAT00000007756", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10071320": { "compartment": "compartment_70101", "id": "reaction_10071320", "reactome": "R-BTA-5323526", "name": "FRAT proteins bind GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041625" ], "products": [ "species_10041627" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10059152": { "compartment": "compartment_70101", "id": "reaction_10059152", "reactome": "R-BTA-1504186", "name": "DVL recruits GSK3beta:AXIN1 to the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043061", "species_10043118" ], "products": [ "species_10043120" ], "modifiers": [], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10083835": { "compartment": "compartment_984", "id": "reaction_10083835", "reactome": "R-BTA-8850831", "name": "KLK5 cleaves and activates KLK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10083828" ], "products": [ "species_10083830", "species_10083832" ], "modifiers": [ [ "species_10083733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000070524" ] }, "reaction_10083741": { "compartment": "compartment_984", "id": "reaction_10083741", "reactome": "R-BTA-8849638", "name": "Dissociation of the SPINK5:KLK5 complex at low pH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083739" ], "products": [ "species_10083733", "species_10083737" ], "modifiers": [ [ "species_351626", "catalyst" ] ], "additional_components": [ "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524", "ENSBTAT00000070524", "ENSBTAT00000025479" ] }, "reaction_10083743": { "compartment": "compartment_984", "id": "reaction_10083743", "reactome": "R-BTA-8849646", "name": "SPINK5(490-624) binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083737" ], "products": [ "species_10083739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000025479", "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10083824": { "compartment": "compartment_984", "id": "reaction_10083824", "reactome": "R-BTA-8850818", "name": "SPINK9 binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083820" ], "products": [ "species_10083822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000081553", "A0A3Q1NK79", "ENSBTAT00000081553", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10077943": { "compartment": "compartment_984", "id": "reaction_10077943", "reactome": "R-BTA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10077940", "catalyst" ] ], "additional_components": [ "E1BA50", "ENSBTAT00000017778", "G3MVZ9", "ENSBTAT00000034704" ] }, "reaction_10084466": { "compartment": "compartment_70101", "id": "reaction_10084466", "reactome": "R-BTA-8857577", "name": "LINC01139 facilitates PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084458" ], "products": [ "species_29370", "species_10084463" ], "modifiers": [ [ "species_10084458", "catalyst" ] ], "additional_components": [ "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10090009": { "compartment": "compartment_876", "id": "reaction_10090009", "reactome": "R-BTA-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090005", "species_10089989" ], "products": [ "species_10090007" ], "modifiers": [], "additional_components": [ "A0A3Q1MD15", "ENSBTAT00000079650", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MD15", "ENSBTAT00000079650" ] }, "reaction_10091896": { "compartment": "compartment_17906", "id": "reaction_10091896", "reactome": "R-BTA-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091892", "species_10091882" ], "products": [ "species_10091894" ], "modifiers": [], "additional_components": [ "F1MY55", "ENSBTAT00000023513", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1MY55", "ENSBTAT00000023513" ] }, "reaction_10090011": { "compartment": "compartment_876", "id": "reaction_10090011", "reactome": "R-BTA-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10089989" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091884": { "compartment": "compartment_876", "id": "reaction_10091884", "reactome": "R-BTA-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091882" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091916": { "compartment": "compartment_20699", "id": "reaction_10091916", "reactome": "R-BTA-9693250", "name": "RHOD binds effectors at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091900", "species_10091912" ], "products": [ "species_10091914" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MZP2", "ENSBTAT00000081390", "A0A3Q1MZP2", "ENSBTAT00000081390", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091902": { "compartment": "compartment_876", "id": "reaction_10091902", "reactome": "R-BTA-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091900" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10089985": { "compartment": "compartment_876", "id": "reaction_10089985", "reactome": "R-BTA-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10089969" ], "products": [ "species_29372", "species_10089965" ], "modifiers": [ [ "species_10089982", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089972": { "compartment": "compartment_876", "id": "reaction_10089972", "reactome": "R-BTA-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089965" ], "products": [ "species_29420", "species_10089969" ], "modifiers": [ [ "species_10089965", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29420", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420" ] }, "reaction_10091878": { "compartment": "compartment_70101", "id": "reaction_10091878", "reactome": "R-BTA-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091874", "species_10089969" ], "products": [ "species_10091876" ], "modifiers": [], "additional_components": [ "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009" ] }, "reaction_10057177": { "compartment": "compartment_876", "id": "reaction_10057177", "reactome": "R-BTA-1250357", "name": "SHC1 binds P-ERBB4 isoform dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057163", "species_10035544" ], "products": [ "species_10057170" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057188": { "compartment": "compartment_876", "id": "reaction_10057188", "reactome": "R-BTA-1250380", "name": "Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057172", "species_10035491" ], "products": [ "species_10057186" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057175": { "compartment": "compartment_876", "id": "reaction_10057175", "reactome": "R-BTA-1250348", "name": "Phosphorylation of SHC1 by ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057170", "species_113592" ], "products": [ "species_10057172", "species_29370" ], "modifiers": [ [ "species_10057170", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057191": { "compartment": "compartment_70101", "id": "reaction_10057191", "reactome": "R-BTA-1250383", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057186", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10083712": { "compartment": "compartment_20699", "id": "reaction_10083712", "reactome": "R-BTA-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_8848483" ], "products": [ "species_429785", "species_76194" ], "modifiers": [ [ "species_10083709", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087371" ] }, "reaction_10083004": { "compartment": "compartment_20699", "id": "reaction_10083004", "reactome": "R-BTA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10082997" ], "products": [ "species_29420", "species_10083001" ], "modifiers": [ [ "species_10082997", "catalyst" ] ], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10083006": { "compartment": "compartment_20699", "id": "reaction_10083006", "reactome": "R-BTA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082993" ], "products": [ "species_10082995" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082999": { "compartment": "compartment_20699", "id": "reaction_10082999", "reactome": "R-BTA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082995" ], "products": [ "species_10082997" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10049867": { "compartment": "compartment_12045", "id": "reaction_10049867", "reactome": "R-BTA-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_29420", "species_449283" ], "modifiers": [ [ "species_10049864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002836" ] }, "reaction_10049851": { "compartment": "compartment_12045", "id": "reaction_10049851", "reactome": "R-BTA-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10049848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003187" ] }, "reaction_10049789": { "compartment": "compartment_17957", "id": "reaction_10049789", "reactome": "R-BTA-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449298" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10049782", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000032212", "ENSBTAT00000000147" ] }, "reaction_10049811": { "compartment": "compartment_17957", "id": "reaction_10049811", "reactome": "R-BTA-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449312" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10049808", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064352", "ENSBTAT00000000147" ] }, "reaction_10049858": { "compartment": "compartment_17957", "id": "reaction_10049858", "reactome": "R-BTA-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449315" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10082941": { "compartment": "compartment_70101", "id": "reaction_10082941", "reactome": "R-BTA-6810464", "name": "NUDT14 hydrolyses UDP-Glc to G1P and UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410" ], "products": [ "species_29548", "species_109402" ], "modifiers": [ [ "species_10082938", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063951" ] }, "reaction_10077816": { "compartment": "compartment_70101", "id": "reaction_10077816", "reactome": "R-BTA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10077800": { "compartment": "compartment_70101", "id": "reaction_10077800", "reactome": "R-BTA-6787533", "name": "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_6787542" ], "products": [ "species_111294", "species_742368" ], "modifiers": [ [ "species_10077797", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055149" ] }, "reaction_10077823": { "compartment": "compartment_70101", "id": "reaction_10077823", "reactome": "R-BTA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10077820", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015992" ] }, "reaction_10077807": { "compartment": "compartment_70101", "id": "reaction_10077807", "reactome": "R-BTA-6787540", "name": "FUK phosphorylates beta-Fuc to Fuc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6787678" ], "products": [ "species_29370", "species_6787542" ], "modifiers": [ [ "species_10077804", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085459" ] }, "reaction_10077826": { "compartment": "compartment_70101", "id": "reaction_10077826", "reactome": "R-BTA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10049831": { "compartment": "compartment_70101", "id": "reaction_10049831", "reactome": "R-BTA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10049828", "catalyst" ] ], "additional_components": [ "Q0VC17", "ENSBTAT00000076692", "Q3SZJ9", "ENSBTAT00000001888" ] }, "reaction_10069368": { "compartment": "compartment_70101", "id": "reaction_10069368", "reactome": "R-BTA-4085021", "name": "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_162756" ], "products": [ "species_110096", "species_4085214" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069320": { "compartment": "compartment_70101", "id": "reaction_10069320", "reactome": "R-BTA-4084976", "name": "NANS converts ManNAc-6-P to Neu5Ac-9-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085225", "species_29492" ], "products": [ "species_29372", "species_4085390" ], "modifiers": [ [ "species_10069317", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025318" ] }, "reaction_10069371": { "compartment": "compartment_70101", "id": "reaction_10069371", "reactome": "R-BTA-4085028", "name": "GNE phosphorylates ManNAc to ManNAc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_4085214" ], "products": [ "species_29370", "species_4085225" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069357": { "compartment": "compartment_70101", "id": "reaction_10069357", "reactome": "R-BTA-4084989", "name": "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085390" ], "products": [ "species_428633", "species_29372" ], "modifiers": [ [ "species_10069354", "catalyst" ] ], "additional_components": [ "A7YWM8", "ENSBTAT00000000918", "species_29926" ] }, "reaction_10069373": { "compartment": "compartment_70101", "id": "reaction_10069373", "reactome": "R-BTA-4085029", "name": "NEU2 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088202" ], "products": [ "species_428633", "species_4088123" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "species_4086294", "species_4086341", "species_4087982", "species_4086277", "species_4088006", "species_4086285", "species_4086301", "ENSBTAT00000027552" ] }, "reaction_10069359": { "compartment": "compartment_70101", "id": "reaction_10069359", "reactome": "R-BTA-4084994", "name": "NEU3 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088088" ], "products": [ "species_428633", "species_4088103" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "species_4086277", "species_4087982", "species_4088006", "species_4086285", "ENSBTAT00000036738" ] }, "reaction_10048958": { "compartment": "compartment_17938", "id": "reaction_10048958", "reactome": "R-BTA-428585", "name": "SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_428639" ], "products": [ "species_428633", "species_70106" ], "modifiers": [ [ "species_10048955", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061225" ] }, "reaction_10069329": { "compartment": "compartment_20699", "id": "reaction_10069329", "reactome": "R-BTA-4084978", "name": "ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4088006" ], "products": [ "species_727810", "species_4087982" ], "modifiers": [ [ "species_10069326", "catalyst" ] ], "additional_components": [ "A0A3Q1N8K2", "ENSBTAT00000074715", "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10051554": { "compartment": "compartment_20699", "id": "reaction_10051554", "reactome": "R-BTA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10051551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018680" ] }, "reaction_10069346": { "compartment": "compartment_20699", "id": "reaction_10069346", "reactome": "R-BTA-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086301" ], "products": [ "species_4086341", "species_727810" ], "modifiers": [ [ "species_10069343", "catalyst" ] ], "additional_components": [ "F1MXN8", "ENSBTAT00000009616", "G3N3B2", "ENSBTAT00000063122", "A0A452DJH9", "ENSBTAT00000061027", "A0A3Q1LRX1", "ENSBTAT00000078008", "F1N6V7", "ENSBTAT00000034693" ] }, "reaction_10069348": { "compartment": "compartment_17963", "id": "reaction_10069348", "reactome": "R-BTA-4084984", "name": "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_4086277", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10069382": { "compartment": "compartment_20699", "id": "reaction_10069382", "reactome": "R-BTA-4085033", "name": "ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_727810", "species_4086294" ], "modifiers": [ [ "species_10069379", "catalyst" ] ], "additional_components": [ "A0A3Q1M347", "ENSBTAT00000083430", "A5D7T4", "ENSBTAT00000070130" ] }, "reaction_10069498": { "compartment": "compartment_12045", "id": "reaction_10069498", "reactome": "R-BTA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10069495", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855" ] }, "reaction_10049818": { "compartment": "compartment_12045", "id": "reaction_10049818", "reactome": "R-BTA-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449744" ], "products": [ "species_29372", "species_449299" ], "modifiers": [ [ "species_10049815", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023834" ] }, "reaction_10049804": { "compartment": "compartment_12045", "id": "reaction_10049804", "reactome": "R-BTA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10049801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014016" ] }, "reaction_10040933": { "compartment": "compartment_70101", "id": "reaction_10040933", "reactome": "R-BTA-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29372", "species_29370", "species_113528", "species_191362" ], "modifiers": [ [ "species_10040930", "catalyst" ] ], "additional_components": [ "Q0P570", "ENSBTAT00000015994" ] }, "reaction_10049797": { "compartment": "compartment_12045", "id": "reaction_10049797", "reactome": "R-BTA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10049794", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070574" ] }, "reaction_10049844": { "compartment": "compartment_12045", "id": "reaction_10049844", "reactome": "R-BTA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10049841", "catalyst" ] ], "additional_components": [ "F1MU60", "ENSBTAT00000006020", "A0A3Q1MW72", "ENSBTAT00000076761" ] }, "reaction_10049860": { "compartment": "compartment_17957", "id": "reaction_10049860", "reactome": "R-BTA-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449371", "species_449311" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10056074": { "compartment": "compartment_20699", "id": "reaction_10056074", "reactome": "R-BTA-1022133", "name": "ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10056071", "catalyst" ] ], "additional_components": [ "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10056061": { "compartment": "compartment_20699", "id": "reaction_10056061", "reactome": "R-BTA-1022129", "name": "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075324" ] }, "reaction_10054431": { "compartment": "compartment_20699", "id": "reaction_10054431", "reactome": "R-BTA-975903", "name": "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981616" ], "modifiers": [ [ "species_10054428", "catalyst" ] ], "additional_components": [ "E1BNB2", "ENSBTAT00000014809", "A6QQ63", "ENSBTAT00000049734" ] }, "reaction_10054467": { "compartment": "compartment_20699", "id": "reaction_10054467", "reactome": "R-BTA-975919", "name": "Addition of galactose by beta 4-galactosyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_975910" ], "products": [ "species_981618" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10054418": { "compartment": "compartment_20699", "id": "reaction_10054418", "reactome": "R-BTA-975902", "name": "ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083430" ] }, "reaction_10054438": { "compartment": "compartment_20699", "id": "reaction_10054438", "reactome": "R-BTA-975916", "name": "Addition of GlcNAc to position 5 by MGAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981617" ], "modifiers": [ [ "species_10054435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084669" ] }, "reaction_10054474": { "compartment": "compartment_17963", "id": "reaction_10054474", "reactome": "R-BTA-975926", "name": "Addition of a bifurcating GlcNAc to the N-glycan by MGAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981613" ], "modifiers": [ [ "species_10054471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016591" ] }, "reaction_10054411": { "compartment": "compartment_20699", "id": "reaction_10054411", "reactome": "R-BTA-975829", "name": "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975819" ], "products": [ "species_205687", "species_975822" ], "modifiers": [ [ "species_10054408", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048092" ] }, "reaction_10076415": { "compartment": "compartment_161320", "id": "reaction_10076415", "reactome": "R-BTA-5693807", "name": "FUCA1 hydrolyses NGP:1,6-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6784247" ], "products": [ "species_6784248", "species_6784249" ], "modifiers": [ [ "species_10076412", "catalyst" ] ], "additional_components": [ "Q2KIM0", "ENSBTAT00000042970" ] }, "reaction_10077710": { "compartment": "compartment_20699", "id": "reaction_10077710", "reactome": "R-BTA-6786034", "name": "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10077694" ], "products": [ "species_10077703", "species_742343" ], "modifiers": [ [ "species_10077707", "catalyst" ] ], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000064164" ] }, "reaction_10077717": { "compartment": "compartment_20699", "id": "reaction_10077717", "reactome": "R-BTA-6786048", "name": "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_6786371" ], "products": [ "species_742343", "species_6786380" ], "modifiers": [ [ "species_10077714", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082120" ] }, "reaction_10076422": { "compartment": "compartment_17963", "id": "reaction_10076422", "reactome": "R-BTA-5693925", "name": "FUT3 transfers L-fucose to Gal1,3GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693930", "species_205683" ], "products": [ "species_5693933", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10076696": { "compartment": "compartment_12045", "id": "reaction_10076696", "reactome": "R-BTA-5694433", "name": "MIA2 binds PREB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076692", "species_10043646" ], "products": [ "species_10076694" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078548", "ENSBTAT00000009307", "E1BL12", "ENSBTAT00000009307", "A0A3Q1LM15", "ENSBTAT00000078548" ] }, "reaction_10076586": { "compartment": "compartment_12045", "id": "reaction_10076586", "reactome": "R-BTA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043590", "species_10043594", "species_10043592" ], "products": [ "species_10043596" ], "modifiers": [], "additional_components": [ "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "ENSBTAT00000004831", "ENSBTAT00000004721", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561" ] }, "reaction_10076590": { "compartment": "compartment_12045", "id": "reaction_10076590", "reactome": "R-BTA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10043651", "species_10043594" ], "products": [ "species_10076588" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "ENSBTAT00000043111", "ENSBTAT00000004831", "A6QNT8", "ENSBTAT00000043111", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10076706": { "compartment": "compartment_12045", "id": "reaction_10076706", "reactome": "R-BTA-5694442", "name": "CNIH2,3 bind GRIA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043622", "species_10043618" ], "products": [ "species_10043624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082647", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647" ] }, "reaction_10076708": { "compartment": "compartment_12045", "id": "reaction_10076708", "reactome": "R-BTA-5694445", "name": "CNIH1 binds TFGA and AREG precursors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043606", "species_10043600" ], "products": [ "species_10043608" ], "modifiers": [], "additional_components": [ "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "ENSBTAT00000025975", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129" ] }, "reaction_10076775": { "compartment": "compartment_12045", "id": "reaction_10076775", "reactome": "R-BTA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580", "species_10043626" ], "products": [ "species_10043628" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076584": { "compartment": "compartment_13959", "id": "reaction_10076584", "reactome": "R-BTA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10076577" ], "products": [ "species_10076581", "species_29420" ], "modifiers": [ [ "species_10076577", "catalyst" ] ], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10076635": { "compartment": "compartment_70101", "id": "reaction_10076635", "reactome": "R-BTA-5694421", "name": "PP6 dephosphorylates SEC24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10076618" ], "products": [ "species_29372", "species_10043653" ], "modifiers": [ [ "species_10076632", "catalyst" ] ], "additional_components": [ "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "E1BN43", "ENSBTAT00000034553", "Q2KIC7", "ENSBTAT00000010568", "G3N214", "ENSBTAT00000066016" ] }, "reaction_10076778": { "compartment": "compartment_70101", "id": "reaction_10076778", "reactome": "R-BTA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043628" ], "products": [ "species_10043655", "species_29372", "species_10043626", "species_10043642" ], "modifiers": [ [ "species_10043628", "catalyst" ] ], "additional_components": [ "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076698": { "compartment": "compartment_13959", "id": "reaction_10076698", "reactome": "R-BTA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076575", "species_10076493", "species_10076537" ], "products": [ "species_10076577" ], "modifiers": [], "additional_components": [ "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10043649": { "compartment": "compartment_70101", "id": "reaction_10043649", "reactome": "R-BTA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043642" ], "products": [ "species_29420", "species_10043580" ], "modifiers": [ [ "species_10043646", "catalyst" ] ], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "ENSBTAT00000009307" ] }, "reaction_10083377": { "compartment": "compartment_6791047", "id": "reaction_10083377", "reactome": "R-BTA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082020", "species_10083373" ], "products": [ "species_10083375" ], "modifiers": [], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10076736": { "compartment": "compartment_6791047", "id": "reaction_10076736", "reactome": "R-BTA-5694446", "name": "BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076704", "species_10076667" ], "products": [ "species_10076596", "species_10076677", "species_10076734", "species_10076602" ], "modifiers": [], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "P41541", "ENSBTAT00000022642", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "P41541", "ENSBTAT00000022642" ] }, "reaction_10076610": { "compartment": "compartment_20699", "id": "reaction_10076610", "reactome": "R-BTA-5694418", "name": "RAB1:GTP binds USO1 and GORASP1:GOLGA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076596", "species_10076581", "species_10076602" ], "products": [ "species_10076608" ], "modifiers": [], "additional_components": [ "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10083380": { "compartment": "compartment_6791047", "id": "reaction_10083380", "reactome": "R-BTA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083375" ], "products": [ "species_10083373", "species_10076493" ], "modifiers": [ [ "species_10083375", "catalyst" ] ], "additional_components": [ "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10082026": { "compartment": "compartment_6791047", "id": "reaction_10082026", "reactome": "R-BTA-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082020", "species_10076602" ], "products": [ "species_10082024" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082045": { "compartment": "compartment_6791047", "id": "reaction_10082045", "reactome": "R-BTA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082036", "species_113592" ], "products": [ "species_29370", "species_10082042" ], "modifiers": [ [ "species_10082036", "catalyst" ] ], "additional_components": [ "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10082038": { "compartment": "compartment_6791047", "id": "reaction_10082038", "reactome": "R-BTA-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082024" ], "products": [ "species_10082036" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10053337": { "compartment": "compartment_20699", "id": "reaction_10053337", "reactome": "R-BTA-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "CHEBI:60629", "CHEBI:60628", "CHEBI:60627", "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053339": { "compartment": "compartment_20699", "id": "reaction_10053339", "reactome": "R-BTA-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053317": { "compartment": "compartment_20699", "id": "reaction_10053317", "reactome": "R-BTA-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053324": { "compartment": "compartment_17963", "id": "reaction_10053324", "reactome": "R-BTA-964759", "name": "Alternative endo-mannosidase I route", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964754" ], "products": [ "species_964744", "species_964746" ], "modifiers": [ [ "species_10053321", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006614" ] }, "reaction_10053331": { "compartment": "compartment_20699", "id": "reaction_10053331", "reactome": "R-BTA-964768", "name": "Addition of GlcNAc to the glycan on the A arm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_964740" ], "products": [ "species_964837", "species_205687" ], "modifiers": [ [ "species_10053328", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066191" ] }, "reaction_10084373": { "compartment": "compartment_984", "id": "reaction_10084373", "reactome": "R-BTA-8855711", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855720", "species_10084369" ], "products": [ "species_10084371" ], "modifiers": [], "additional_components": [ "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "species_8855720" ] }, "reaction_10056058": { "compartment": "compartment_70101", "id": "reaction_10056058", "reactome": "R-BTA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056054" ], "products": [ "species_10056056" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "CHEBI:60627", "CHEBI:60628", "species_915149", "CHEBI:60629", "species_964740", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10089391": { "compartment": "compartment_5460", "id": "reaction_10089391", "reactome": "R-BTA-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089384" ], "products": [], "modifiers": [ [ "species_10089388", "catalyst" ] ], "additional_components": [ "Q02372", "ENSBTAT00000000100", "ENSBTAT00000046212" ] }, "reaction_10056912": { "compartment": "compartment_24339", "id": "reaction_10056912", "reactome": "R-BTA-1236955", "name": "Movement of clathrin coated vesicles into early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056833" ], "products": [ "species_10056803" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056835": { "compartment": "compartment_24339", "id": "reaction_10056835", "reactome": "R-BTA-1236941", "name": "Internalization of receptor bound antigen into clathrin coted vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056819" ], "products": [ "species_10056833" ], "modifiers": [], "additional_components": [ "species_1236715", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056805": { "compartment": "compartment_171043", "id": "reaction_10056805", "reactome": "R-BTA-1236940", "name": "Exogenous soluble antigen targeted to more stable early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056803" ], "products": [ "species_1236715", "species_10056801" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10087823": { "compartment": "compartment_6791047", "id": "reaction_10087823", "reactome": "R-BTA-8951595", "name": "CALR, TAP, TAPBP dissociate from SEC22B:STX4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084863" ], "products": [ "species_10087813", "species_10087809", "species_10087821", "species_10087819" ], "modifiers": [], "additional_components": [ "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899", "A0A3Q1MMA1", "ENSBTAT00000066705", "A0A452DIB2", "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10084865": { "compartment": "compartment_6791047", "id": "reaction_10084865", "reactome": "R-BTA-8863858", "name": "SEC22B, CALR, STX4, TAP and TAPBP bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084853", "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "products": [ "species_10084863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10084867": { "compartment": "compartment_6791047", "id": "reaction_10084867", "reactome": "R-BTA-8863914", "name": "Transport of SEC22B, TAP and PLC from ER to ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10055441", "species_10055470", "species_10055468" ], "products": [ "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10056982": { "compartment": "compartment_1222693", "id": "reaction_10056982", "reactome": "R-BTA-1236965", "name": "Export of peptide loaded MHC class I complex to PM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056980" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056910": { "compartment": "compartment_171062", "id": "reaction_10056910", "reactome": "R-BTA-1236954", "name": "Trimming of peptides by IRAP in endocytic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236722" ], "products": [ "species_8943711", "species_1236727" ], "modifiers": [ [ "species_10056907", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10056914": { "compartment": "compartment_876", "id": "reaction_10056914", "reactome": "R-BTA-1236964", "name": "Translocation of peptide bound MHC class I complex to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056901" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056903": { "compartment": "compartment_171043", "id": "reaction_10056903", "reactome": "R-BTA-1236943", "name": "Loading of antigen peptide onto MHC class I molecule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056899", "species_1236727" ], "products": [ "species_10056901" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10057004": { "compartment": "compartment_263698", "id": "reaction_10057004", "reactome": "R-BTA-1236967", "name": "Alkalization of the phagosomal lumen by NOX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_2000347" ], "products": [ "species_2000345", "species_2000349", "species_2000348" ], "modifiers": [ [ "species_10057001", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657" ] }, "reaction_10041962": { "compartment": "compartment_876", "id": "reaction_10041962", "reactome": "R-BTA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10041959", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042889" ] }, "reaction_10041955": { "compartment": "compartment_70101", "id": "reaction_10041955", "reactome": "R-BTA-198813", "name": "GSTO dimers reduce DeHA to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_198827" ], "products": [ "species_198816", "species_111745" ], "modifiers": [ [ "species_10041952", "catalyst" ] ], "additional_components": [ "E1BED9", "ENSBTAT00000005211" ] }, "reaction_10041975": { "compartment": "compartment_876", "id": "reaction_10041975", "reactome": "R-BTA-198870", "name": "SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198836", "species_74113" ], "products": [ "species_83910", "species_198816" ], "modifiers": [ [ "species_10041972", "catalyst" ] ], "additional_components": [ "E1BI45", "ENSBTAT00000010823", "E1BP61", "ENSBTAT00000083275" ] }, "reaction_10083656": { "compartment": "compartment_70101", "id": "reaction_10083656", "reactome": "R-BTA-8848930", "name": "PTK6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083480" ], "products": [ "species_10083654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122" ] }, "reaction_10083672": { "compartment": "compartment_7660", "id": "reaction_10083672", "reactome": "R-BTA-8848975", "name": "PTK6 phosphorylates KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10083662" ], "products": [ "species_10083654", "species_113582", "species_10083669" ], "modifiers": [ [ "species_10083662", "catalyst" ] ], "additional_components": [ "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083676": { "compartment": "compartment_7660", "id": "reaction_10083676", "reactome": "R-BTA-8848993", "name": "Phosphorylated KHDRBS1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083669" ], "products": [ "species_10083674" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016581", "ENSBTAT00000016581" ] }, "reaction_10083664": { "compartment": "compartment_7660", "id": "reaction_10083664", "reactome": "R-BTA-8848939", "name": "PTK6 binds KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083654", "species_10083660" ], "products": [ "species_10083662" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10037748": { "compartment": "compartment_17957", "id": "reaction_10037748", "reactome": "R-BTA-140355", "name": "Arachidonic acid is oxidised to PGG2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10037751": { "compartment": "compartment_17957", "id": "reaction_10037751", "reactome": "R-BTA-140359", "name": "PGG2 is reduced to PGH2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10063448": { "compartment": "compartment_17957", "id": "reaction_10063448", "reactome": "R-BTA-2046095", "name": "Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046060", "species_113601" ], "products": [ "species_2046048", "species_113519", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063450": { "compartment": "compartment_12045", "id": "reaction_10063450", "reactome": "R-BTA-2046096", "name": "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046063" ], "products": [ "species_194653", "species_113519", "species_2046042" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063452": { "compartment": "compartment_17957", "id": "reaction_10063452", "reactome": "R-BTA-2046097", "name": "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046048", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046050" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063454": { "compartment": "compartment_12045", "id": "reaction_10063454", "reactome": "R-BTA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063442": { "compartment": "compartment_17957", "id": "reaction_10063442", "reactome": "R-BTA-2046092", "name": "Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046045" ], "products": [ "species_194653", "species_113519", "species_2046053" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063413": { "compartment": "compartment_12045", "id": "reaction_10063413", "reactome": "R-BTA-2046083", "name": "Elongation of arachidonyl-CoA to docosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046053", "species_113601" ], "products": [ "species_113519", "species_162743", "species_159751", "species_2046060" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063444": { "compartment": "compartment_12045", "id": "reaction_10063444", "reactome": "R-BTA-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_5228339", "species_2046055", "species_211606" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063446": { "compartment": "compartment_17957", "id": "reaction_10063446", "reactome": "R-BTA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063437": { "compartment": "compartment_17957", "id": "reaction_10063437", "reactome": "R-BTA-2046089", "name": "Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046051", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046059" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063420": { "compartment": "compartment_12045", "id": "reaction_10063420", "reactome": "R-BTA-2046084", "name": "Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046062" ], "products": [ "species_194653", "species_113519", "species_2046052" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063425": { "compartment": "compartment_12045", "id": "reaction_10063425", "reactome": "R-BTA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063456": { "compartment": "compartment_12045", "id": "reaction_10063456", "reactome": "R-BTA-2046100", "name": "Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046059", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046057", "species_162743", "species_159751" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063440": { "compartment": "compartment_17957", "id": "reaction_10063440", "reactome": "R-BTA-2046090", "name": "Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046057", "species_113601" ], "products": [ "species_113519", "species_2046065", "species_113564", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063570": { "compartment": "compartment_17951", "id": "reaction_10063570", "reactome": "R-BTA-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10063573": { "compartment": "compartment_17951", "id": "reaction_10063573", "reactome": "R-BTA-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_2066762" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10063428": { "compartment": "compartment_17957", "id": "reaction_10063428", "reactome": "R-BTA-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_426639", "species_211606", "species_2046047" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063430": { "compartment": "compartment_17957", "id": "reaction_10063430", "reactome": "R-BTA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10033912": { "compartment": "compartment_5460", "id": "reaction_10033912", "reactome": "R-BTA-71031", "name": "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70843", "species_113593", "species_29376" ], "products": [ "species_113548", "species_113581", "species_71019" ], "modifiers": [ [ "species_10033909", "catalyst" ] ], "additional_components": [ "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10033896": { "compartment": "compartment_5460", "id": "reaction_10033896", "reactome": "R-BTA-71020", "name": "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71019" ], "products": [ "species_71009" ], "modifiers": [ [ "species_10033893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000049741" ] }, "reaction_10033889": { "compartment": "compartment_5460", "id": "reaction_10033889", "reactome": "R-BTA-71010", "name": "MUT isomerises L-MM-CoA to SUCC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71009" ], "products": [ "species_70958" ], "modifiers": [ [ "species_10033884", "catalyst" ] ], "additional_components": [ "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10075631": { "compartment": "compartment_5460", "id": "reaction_10075631", "reactome": "R-BTA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10075628", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_30495", "CHEBI:59554", "E1BA10", "ENSBTAP00000020594", "A6QQA9", "ENSBTAT00000074250", "F1N234", "ENSBTAT00000074250", "E1BAC0", "ENSBTAT00000000922" ] }, "reaction_10036029": { "compartment": "compartment_5460", "id": "reaction_10036029", "reactome": "R-BTA-77331", "name": "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77330" ], "products": [ "species_113529", "species_29362", "species_77328" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036038": { "compartment": "compartment_5460", "id": "reaction_10036038", "reactome": "R-BTA-77338", "name": "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77337" ], "products": [ "species_77332", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036027": { "compartment": "compartment_5460", "id": "reaction_10036027", "reactome": "R-BTA-77323", "name": "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77322", "species_113526" ], "products": [ "species_77320", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036040": { "compartment": "compartment_5460", "id": "reaction_10036040", "reactome": "R-BTA-77342", "name": "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77341", "species_113526" ], "products": [ "species_77339", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036042": { "compartment": "compartment_5460", "id": "reaction_10036042", "reactome": "R-BTA-77345", "name": "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77308", "species_113596" ], "products": [ "species_77343", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036012": { "compartment": "compartment_5460", "id": "reaction_10036012", "reactome": "R-BTA-77254", "name": "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77252" ], "products": [ "species_113529", "species_77253", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036021": { "compartment": "compartment_5460", "id": "reaction_10036021", "reactome": "R-BTA-77263", "name": "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77261" ], "products": [ "species_77255", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10036025": { "compartment": "compartment_5460", "id": "reaction_10036025", "reactome": "R-BTA-77312", "name": "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77251" ], "products": [ "species_73871", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036023": { "compartment": "compartment_5460", "id": "reaction_10036023", "reactome": "R-BTA-77274", "name": "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77272" ], "products": [ "species_77273", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10086403": { "compartment": "compartment_70616", "id": "reaction_10086403", "reactome": "R-BTA-8933547", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977314", "species_10086393" ], "products": [ "species_29374", "species_10086396" ], "modifiers": [ [ "species_10086400", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008382", "ENSBTAT00000008382", "ENSBTAT00000003130" ] }, "reaction_10036664": { "compartment": "compartment_5460", "id": "reaction_10036664", "reactome": "R-BTA-109998", "name": "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109994" ], "products": [ "species_77343" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036218": { "compartment": "compartment_5460", "id": "reaction_10036218", "reactome": "R-BTA-109338", "name": "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77358" ], "products": [ "species_77360" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036220": { "compartment": "compartment_5460", "id": "reaction_10036220", "reactome": "R-BTA-109341", "name": "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_109986" ], "products": [ "species_109990", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10075607": { "compartment": "compartment_70101", "id": "reaction_10075607", "reactome": "R-BTA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5690044" ], "products": [ "species_5690064", "species_76194" ], "modifiers": [ [ "species_10075600", "catalyst" ], [ "species_10075605", "catalyst" ] ], "additional_components": [ "CHEBI:61907", "CHEBI:33184", "CHEBI:59554", "species_30495", "F6QGE6", "ENSBTAT00000021731", "A6QQA9", "ENSBTAT00000074250", "A0A3Q1MI69", "ENSBTAT00000075163", "E1BNW7", "ENSBTAT00000014753", "ENSBTAT00000024898" ] }, "reaction_10076806": { "compartment": "compartment_5460", "id": "reaction_10076806", "reactome": "R-BTA-5695980", "name": "ACAD10 dehydrogenates S-2MPDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_5695946" ], "products": [ "species_5695949", "species_31649" ], "modifiers": [ [ "species_10076803", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080862" ] }, "reaction_10042860": { "compartment": "compartment_70101", "id": "reaction_10042860", "reactome": "R-BTA-200406", "name": "CPT1A,B transfers PALM to CAR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549207", "species_200993" ], "products": [ "species_201034", "species_76194" ], "modifiers": [ [ "species_10042857", "catalyst" ], [ "species_29508", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMV3", "ENSBTAT00000069870", "Q58DK1", "ENSBTAT00000021357" ] }, "reaction_10042897": { "compartment": "compartment_17927", "id": "reaction_10042897", "reactome": "R-BTA-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10042894", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000217" ] }, "reaction_10085185": { "compartment": "compartment_70101", "id": "reaction_10085185", "reactome": "R-BTA-8866941", "name": "MID1IP1 binds THRSP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085181", "species_10085177" ], "products": [ "species_10085183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015490", "ENSBTAT00000015231", "Q08E46", "ENSBTAT00000015231", "A0A3S5ZPK2", "ENSBTAT00000015490" ] }, "reaction_10077001": { "compartment": "compartment_12045", "id": "reaction_10077001", "reactome": "R-BTA-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192172", "species_5696426" ], "products": [ "species_5696412", "species_162743" ], "modifiers": [ [ "species_10076998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025081" ] }, "reaction_10044657": { "compartment": "compartment_876", "id": "reaction_10044657", "reactome": "R-BTA-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266013" ], "products": [ "species_266074", "species_210382" ], "modifiers": [ [ "species_10044654", "catalyst" ] ], "additional_components": [ "F1MYJ3", "ENSBTAT00000023658", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10064482": { "compartment": "compartment_12045", "id": "reaction_10064482", "reactome": "R-BTA-2161745", "name": "20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2161636" ], "products": [ "species_29356", "species_29366", "species_2142740" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064581": { "compartment": "compartment_70101", "id": "reaction_10064581", "reactome": "R-BTA-2162019", "name": "LTA4 is converted to EXA4 by ALOX15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281" ], "products": [ "species_2142772" ], "modifiers": [ [ "species_10064560", "catalyst" ] ], "additional_components": [ "P27479", "ENSBTAT00000015911", "species_71067" ] }, "reaction_10064503": { "compartment": "compartment_12045", "id": "reaction_10064503", "reactome": "R-BTA-2161792", "name": "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2142740" ], "products": [ "species_2161582", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064578": { "compartment": "compartment_70101", "id": "reaction_10064578", "reactome": "R-BTA-2162002", "name": "Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142718" ], "modifiers": [ [ "species_10064575", "catalyst" ] ], "additional_components": [ "F1MXW0", "ENSBTAT00000011570", "species_71067", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064546": { "compartment": "compartment_12045", "id": "reaction_10064546", "reactome": "R-BTA-2161951", "name": "Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142738" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064554": { "compartment": "compartment_70101", "id": "reaction_10064554", "reactome": "R-BTA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064565": { "compartment": "compartment_70101", "id": "reaction_10064565", "reactome": "R-BTA-2161964", "name": "Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142811" ], "modifiers": [ [ "species_10064562", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064567": { "compartment": "compartment_70101", "id": "reaction_10064567", "reactome": "R-BTA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064534": { "compartment": "compartment_70101", "id": "reaction_10064534", "reactome": "R-BTA-2161948", "name": "Arachidonic acid is converted to 12-oxoETE by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29768" ], "products": [ "species_2142745" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10076382": { "compartment": "compartment_12045", "id": "reaction_10076382", "reactome": "R-BTA-5693742", "name": "FAAH hydrolyses AEA to AA and ETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693754" ], "products": [ "species_1498751", "species_29768" ], "modifiers": [ [ "species_10076379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071864" ] }, "reaction_10064506": { "compartment": "compartment_70101", "id": "reaction_10064506", "reactome": "R-BTA-2161794", "name": "Arachidonic acid is converted to HXA3/B3 by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2162031" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:36190", "CHEBI:34784", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10086336": { "compartment": "compartment_984", "id": "reaction_10086336", "reactome": "R-BTA-8932633", "name": "PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8932801" ], "products": [ "species_8932804" ], "modifiers": [ [ "species_10086333", "catalyst" ] ], "additional_components": [ "Q1JQD3", "ENSBTAT00000049076", "species_74016", "Q2KIW1", "ENSBTAT00000020790" ] }, "reaction_10064521": { "compartment": "compartment_12045", "id": "reaction_10064521", "reactome": "R-BTA-2161890", "name": "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142739" ], "modifiers": [ [ "species_10064518", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10064526": { "compartment": "compartment_12045", "id": "reaction_10064526", "reactome": "R-BTA-2161899", "name": "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_2161753", "species_29366" ], "modifiers": [ [ "species_10064523", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "A0A3S5ZP79", "ENSBTAT00000027159", "F1MM10", "ENSBTAT00000061300", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10065210": { "compartment": "compartment_17957", "id": "reaction_10065210", "reactome": "R-BTA-2309773", "name": "PGG2 is reduced to PGH2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10065205", "catalyst" ], [ "species_549282", "catalyst" ], [ "species_10065208", "inhibitor" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064442": { "compartment": "compartment_70101", "id": "reaction_10064442", "reactome": "R-BTA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064474": { "compartment": "compartment_12045", "id": "reaction_10064474", "reactome": "R-BTA-2161660", "name": "PGH2 is isomerised to PGE2 by PTGES", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10064471", "catalyst" ] ], "additional_components": [ "species_29450", "Q95L14", "ENSBTAT00000025912" ] }, "reaction_10065213": { "compartment": "compartment_70101", "id": "reaction_10065213", "reactome": "R-BTA-2309779", "name": "PTGS2 dimer binds PTGS2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9716714", "species_10065205" ], "products": [ "species_10065208" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064445": { "compartment": "compartment_70101", "id": "reaction_10064445", "reactome": "R-BTA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064479": { "compartment": "compartment_70101", "id": "reaction_10064479", "reactome": "R-BTA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10064476", "catalyst" ] ], "additional_components": [ "species_29450", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10064465": { "compartment": "compartment_70101", "id": "reaction_10064465", "reactome": "R-BTA-2161651", "name": "PGE2 is converted to PGF2a by CBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265287" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10064462", "catalyst" ] ], "additional_components": [ "A0A3Q1NG39", "ENSBTAT00000084736", "Q3T0T9", "ENSBTAT00000043292" ] }, "reaction_10044599": { "compartment": "compartment_70101", "id": "reaction_10044599", "reactome": "R-BTA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10044596", "catalyst" ] ], "additional_components": [ "A0A3Q1LFK5", "ENSBTAT00000071669", "A0A452DIU3", "ENSBTAT00000023908" ] }, "reaction_10065225": { "compartment": "compartment_70101", "id": "reaction_10065225", "reactome": "R-BTA-2314686", "name": "Aspirin acetylates PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065205", "species_2314693" ], "products": [ "species_10064543", "species_2314690" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10065216": { "compartment": "compartment_17957", "id": "reaction_10065216", "reactome": "R-BTA-2309787", "name": "Arachidonic acid is oxidised to PGG2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064452": { "compartment": "compartment_12045", "id": "reaction_10064452", "reactome": "R-BTA-2161620", "name": "PGH2 is isomerised to PGD2 by PTGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30138" ], "products": [ "species_2161634" ], "modifiers": [ [ "species_10064449", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020065" ] }, "reaction_10065223": { "compartment": "compartment_70101", "id": "reaction_10065223", "reactome": "R-BTA-2314678", "name": "Aspirin acetylates PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037745", "species_2314693" ], "products": [ "species_10065221", "species_2314690" ], "modifiers": [], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355", "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10064511": { "compartment": "compartment_12045", "id": "reaction_10064511", "reactome": "R-BTA-2161795", "name": "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2161639" ], "modifiers": [ [ "species_10064508", "catalyst" ] ], "additional_components": [ "CHEBI:63995", "CHEBI:63994", "CHEBI:63579", "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064531": { "compartment": "compartment_12045", "id": "reaction_10064531", "reactome": "R-BTA-2161940", "name": "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142780" ], "modifiers": [ [ "species_10064528", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785", "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064516": { "compartment": "compartment_12045", "id": "reaction_10064516", "reactome": "R-BTA-2161814", "name": "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142836" ], "modifiers": [ [ "species_10064513", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1N3I8", "ENSBTAT00000021785", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10047033": { "compartment": "compartment_17951", "id": "reaction_10047033", "reactome": "R-BTA-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047030", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1LWZ7", "ENSBTAT00000082299", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10047056": { "compartment": "compartment_17951", "id": "reaction_10047056", "reactome": "R-BTA-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_353123" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10047042": { "compartment": "compartment_17951", "id": "reaction_10047042", "reactome": "R-BTA-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047039", "catalyst" ] ], "additional_components": [ "A4IFA4", "ENSBTAT00000044120", "species_113596" ] }, "reaction_10047044": { "compartment": "compartment_17951", "id": "reaction_10047044", "reactome": "R-BTA-389897", "name": "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389569" ], "products": [ "species_389893" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10077835": { "compartment": "compartment_17951", "id": "reaction_10077835", "reactome": "R-BTA-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_6787810" ], "products": [ "species_113575", "species_6787814" ], "modifiers": [ [ "species_10077832", "catalyst" ] ], "additional_components": [ "Q3ZBW2", "ENSBTAT00000000134" ] }, "reaction_10077784": { "compartment": "compartment_17951", "id": "reaction_10077784", "reactome": "R-BTA-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6786723", "species_113602" ], "products": [ "species_6786715", "species_389556" ], "modifiers": [ [ "species_10077781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072961" ] }, "reaction_10075576": { "compartment": "compartment_17951", "id": "reaction_10075576", "reactome": "R-BTA-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690520", "species_141343" ], "products": [ "species_5690539", "species_193514" ], "modifiers": [ [ "species_10075573", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "CHEBI:59554", "species_30495", "A0A3Q1N6L4", "ENSBTAT00000074004", "A0A3S5ZPS3", "ENSBTAT00000003683", "E1BBG0", "ENSBTAT00000013568" ] }, "reaction_10047053": { "compartment": "compartment_17951", "id": "reaction_10047053", "reactome": "R-BTA-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10082880": { "compartment": "compartment_17951", "id": "reaction_10082880", "reactome": "R-BTA-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10082877", "catalyst" ] ], "additional_components": [ "A0A3Q1LP28", "ENSBTAT00000083505" ] }, "reaction_10054592": { "compartment": "compartment_17951", "id": "reaction_10054592", "reactome": "R-BTA-977317", "name": "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977323" ], "products": [ "species_353123", "species_389536" ], "modifiers": [ [ "species_10054589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005562" ] }, "reaction_10047058": { "compartment": "compartment_17947", "id": "reaction_10047058", "reactome": "R-BTA-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10082889": { "compartment": "compartment_17947", "id": "reaction_10082889", "reactome": "R-BTA-6809810", "name": "PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6809811", "species_113602" ], "products": [ "species_389615", "species_389556" ], "modifiers": [ [ "species_10082886", "catalyst" ] ], "additional_components": [ "G3X6L7", "ENSBTAT00000008962" ] }, "reaction_10047001": { "compartment": "compartment_17951", "id": "reaction_10047001", "reactome": "R-BTA-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389615", "species_389537" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10046998", "catalyst" ] ], "additional_components": [ "species_71067", "O18778", "ENSBTAT00000010126" ] }, "reaction_10046984": { "compartment": "compartment_17951", "id": "reaction_10046984", "reactome": "R-BTA-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10046981", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10046989": { "compartment": "compartment_17951", "id": "reaction_10046989", "reactome": "R-BTA-389622", "name": "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389596", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389615", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10046992": { "compartment": "compartment_17951", "id": "reaction_10046992", "reactome": "R-BTA-389632", "name": "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6811612", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389569", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10083389": { "compartment": "compartment_12045", "id": "reaction_10083389", "reactome": "R-BTA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10083386", "catalyst" ] ], "additional_components": [ "Q2KIA4", "ENSBTAT00000025820" ] }, "reaction_10051261": { "compartment": "compartment_70101", "id": "reaction_10051261", "reactome": "R-BTA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10051258", "catalyst" ] ], "additional_components": [ "A6QNQ7", "ENSBTAT00000067475", "E1BBR7", "ENSBTAT00000020842" ] }, "reaction_10042961": { "compartment": "compartment_70101", "id": "reaction_10042961", "reactome": "R-BTA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10042958", "catalyst" ] ], "additional_components": [ "Q1LZF6", "ENSBTAT00000064114", "A0A3Q1LPX2", "ENSBTAT00000080693", "A0A3Q1LWT4", "ENSBTAT00000078831", "F1MEX9", "ENSBTAT00000022939" ] }, "reaction_10074353": { "compartment": "compartment_12045", "id": "reaction_10074353", "reactome": "R-BTA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10074350", "catalyst" ] ], "additional_components": [ "F1MXJ1", "ENSBTAT00000046976" ] }, "reaction_10051252": { "compartment": "compartment_70101", "id": "reaction_10051252", "reactome": "R-BTA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10044985": { "compartment": "compartment_876", "id": "reaction_10044985", "reactome": "R-BTA-352174", "name": "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352186", "species_70106", "species_74113" ], "products": [ "species_351626", "species_352169", "species_83910" ], "modifiers": [ [ "species_10044982", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_29612", "species_29642", "species_29472", "species_352036", "species_29642", "species_29612", "ENSBTAT00000011214" ] }, "reaction_10044955": { "compartment": "compartment_876", "id": "reaction_10044955", "reactome": "R-BTA-352103", "name": "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044952", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000072259" ] }, "reaction_10045501": { "compartment": "compartment_876", "id": "reaction_10045501", "reactome": "R-BTA-375776", "name": "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045498", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000019060" ] }, "reaction_10044978": { "compartment": "compartment_876", "id": "reaction_10044978", "reactome": "R-BTA-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10044975", "catalyst" ] ], "additional_components": [ "species_352006", "species_352030", "species_351993", "species_352030", "species_352006", "species_351993", "ENSBTAT00000012176" ] }, "reaction_10044948": { "compartment": "compartment_876", "id": "reaction_10044948", "reactome": "R-BTA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10044945", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "CHEBI:58045", "species_379717", "species_351990", "species_111707", "species_379732", "species_29642", "CHEBI:57427", "species_174390", "CHEBI:18240", "species_29702", "species_29472", "species_379717", "species_351990", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:18240", "CHEBI:58045", "species_29702", "species_352036", "species_29642", "species_111707", "ENSBTAT00000076418" ] }, "reaction_10045494": { "compartment": "compartment_876", "id": "reaction_10045494", "reactome": "R-BTA-375770", "name": "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045491", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000009736" ] }, "reaction_10088905": { "compartment": "compartment_70101", "id": "reaction_10088905", "reactome": "R-BTA-8959781", "name": "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959777" ], "products": [ "species_8959775" ], "modifiers": [ [ "species_10088902", "catalyst" ] ], "additional_components": [ "CHEBI:28229", "species_113586", "species_113530", "species_29612", "CHEBI:32551", "CHEBI:27747", "species_113586", "CHEBI:32551", "species_113530", "species_29612", "CHEBI:28229", "CHEBI:27747", "ENSBTAT00000018163" ] }, "reaction_10085384": { "compartment": "compartment_876", "id": "reaction_10085384", "reactome": "R-BTA-8870354", "name": "SLC36A4 transports extracellular L-Pro to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033" ], "products": [ "species_113538" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10045480": { "compartment": "compartment_876", "id": "reaction_10045480", "reactome": "R-BTA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10045477", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "species_29472", "CHEBI:58045", "species_111707", "species_379732", "species_29424", "CHEBI:57427", "species_174390", "species_352030", "species_351993", "species_29702", "species_29424", "species_29472", "species_352030", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_352036", "species_111707", "species_352006", "species_351993", "ENSBTAT00000064818" ] }, "reaction_10044971": { "compartment": "compartment_876", "id": "reaction_10044971", "reactome": "R-BTA-352136", "name": "SLC38A4 (ATA3)-mediated uptake of arginine and lysine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352128" ], "products": [ "species_352135" ], "modifiers": [ [ "species_10044968", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000070473" ] }, "reaction_10044941": { "compartment": "compartment_876", "id": "reaction_10044941", "reactome": "R-BTA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10044938", "catalyst" ] ], "additional_components": [ "species_73590", "species_428571", "species_352015", "CHEBI:48950", "CHEBI:48950", "species_73590", "species_352015", "species_428571", "ENSBTAT00000067153" ] }, "reaction_10045487": { "compartment": "compartment_876", "id": "reaction_10045487", "reactome": "R-BTA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10045484", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "CHEBI:58045", "species_29612", "species_379732", "species_29424", "species_113530", "species_73590", "CHEBI:32551", "species_111707", "CHEBI:57427", "species_174390", "species_29702", "species_379732", "species_29702", "species_29612", "CHEBI:32551", "species_29424", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_73590", "species_352036", "species_111707", "species_113530", "species_352006", "ENSBTAT00000083685" ] }, "reaction_10045473": { "compartment": "compartment_876", "id": "reaction_10045473", "reactome": "R-BTA-375405", "name": "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_375409" ], "products": [ "species_70106", "species_375414" ], "modifiers": [ [ "species_10045470", "catalyst" ] ], "additional_components": [ "species_379717", "species_29424", "species_29424", "species_379717", "ENSBTAT00000027731" ] }, "reaction_10044962": { "compartment": "compartment_876", "id": "reaction_10044962", "reactome": "R-BTA-352107", "name": "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044959", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000015260" ] }, "reaction_10044964": { "compartment": "compartment_876", "id": "reaction_10044964", "reactome": "R-BTA-352108", "name": "SLC38A2 (ATA2)-mediated uptake of neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352091", "species_74113" ], "products": [ "species_352088", "species_83910" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_379717", "species_351990", "species_379732", "species_29642", "species_29424", "CHEBI:57427", "species_174390", "species_29472", "species_29424", "species_379717", "species_379732", "species_351990", "CHEBI:57427", "species_174390", "species_352036", "species_29642", "ENSBTAT00000014749" ] }, "reaction_10044934": { "compartment": "compartment_876", "id": "reaction_10044934", "reactome": "R-BTA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10044931", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016676" ] }, "reaction_10039272": { "compartment": "compartment_984", "id": "reaction_10039272", "reactome": "R-BTA-166542", "name": "beta-NGF dimer binds to TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039264", "species_10039258" ], "products": [ "species_10039266" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10040684": { "compartment": "compartment_876", "id": "reaction_10040684", "reactome": "R-BTA-190065", "name": "Activated TrkA receptor internalizes to endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039569" ], "products": [ "species_10039684" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039270": { "compartment": "compartment_876", "id": "reaction_10039270", "reactome": "R-BTA-166538", "name": "The bound receptor dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039266", "species_10039258" ], "products": [ "species_10039268" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10088473": { "compartment": "compartment_17957", "id": "reaction_10088473", "reactome": "R-BTA-8952289", "name": "FAM20C phosphorylates FAM20C substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088246", "species_8931885" ], "products": [ "species_10088464", "species_8931884" ], "modifiers": [ [ "species_10088246", "catalyst" ], [ "species_10088471", "catalyst" ] ], "additional_components": [ "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MI67", "ENSBTAT00000025557", "A0A3Q1NJR8", "ENSBTAT00000071014", "Q2KJH1", "ENSBTAT00000004992", "A0A5H1ZRH6", "ENSBTAT00000028238", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3X6N3", "ENSBTAT00000009564", "E1B8P3", "ENSBTAT00000002384", "P11116", "ENSBTAT00000020080", "F1MD77", "ENSBTAT00000015881", "P81644", "ENSBTAT00000012138", "A0A3Q1LEU1", "ENSBTAT00000081148", "E1BDK6", "ENSBTAT00000057452", "E1BG25", "ENSBTAT00000046533", "F1MD94", "ENSBTAT00000027836", "A4FUZ9", "ENSBTAT00000026336", "A0A452DII7", "ENSBTAT00000016252", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1MS36", "ENSBTAT00000076629", "Q95M18", "ENSBTAT00000004364", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "A0A3Q1MY30", "ENSBTAT00000082437", "E1BJF8", "ENSBTAT00000022706", "P02817", "ENSBTAT00000016034", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A140T8C8", "ENSBTAT00000053071", "P12763", "ENSBTAT00000000673", "F1MEA1", "ENSBTAT00000024433", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "F1MY12", "ENSBTAT00000016092", "F6RJ01", "ENSBTAT00000027753", "A0A3Q1LRR3", "ENSBTAT00000074422", "G3N348", "ENSBTAT00000082028", "P01035", "ENSBTAT00000000790", "A0A3Q1LMK4", "ENSBTAT00000076179", "A0A452DJ03", "ENSBTAT00000028372", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "E1BLA8", "ENSBTAT00000044756", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LIS3", "ENSBTAT00000085388", "Q27967", "ENSBTAT00000002631", "A0A3Q1N9Y5", "ENSBTAT00000085713", "G3X724", "ENSBTAT00000065790", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QPR4", "ENSBTAT00000044682", "A6QQR3", "ENSBTAT00000044682", "A0A3Q1MEX5", "ENSBTAT00000072231", "A0A3Q1NAS1", "ENSBTAT00000074235", "E1BHJ7", "ENSBTAT00000016190", "F6QSG5", "ENSBTAT00000056456", "A0A3Q1NIX0", "ENSBTAT00000078756", "A6QP86", "ENSBTAT00000054074", "G3N2W6", "ENSBTAT00000065790", "G3N2L2", "ENSBTAT00000063521", "Q6PX77", "ENSBTAT00000064918", "P34955", "ENSBTAT00000072441", "P01211", "ENSBTAT00000087134", "Q1LZE9", "ENSBTAT00000020194", "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MJW4", "ENSBTAT00000001439" ] }, "reaction_10046621": { "compartment": "compartment_984", "id": "reaction_10046621", "reactome": "R-BTA-381487", "name": "IGFBP1 binds IGF forming IGF:IGFBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046613", "species_10046617" ], "products": [ "species_10046619" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014713", "ENSBTAT00000064194", "P24591", "ENSBTAT00000064194", "P07455", "ENSBTAT00000014713" ] }, "reaction_10068959": { "compartment": "compartment_7660", "id": "reaction_10068959", "reactome": "R-BTA-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068951", "species_10068947", "species_10068943", "species_10068955" ], "products": [ "species_10068957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064363", "ENSBTAT00000074434", "ENSBTAT00000002664", "ENSBTAT00000018360", "G3X746", "ENSBTAT00000018360", "Q2KIG1", "ENSBTAT00000002664", "A0A3Q1NMK6", "ENSBTAT00000074434", "G3N0Y4", "ENSBTAT00000064363" ] }, "reaction_10061480": { "compartment": "compartment_876", "id": "reaction_10061480", "reactome": "R-BTA-1963582", "name": "Trans-autophosphorylation of ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10057121" ], "modifiers": [ [ "species_10061477", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10061469": { "compartment": "compartment_876", "id": "reaction_10061469", "reactome": "R-BTA-1963581", "name": "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10061466" ], "products": [ "species_29370", "species_10057130" ], "modifiers": [ [ "species_10061466", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10057692": { "compartment": "compartment_70101", "id": "reaction_10057692", "reactome": "R-BTA-1306969", "name": "GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10057688" ], "products": [ "species_10057690" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10057695": { "compartment": "compartment_876", "id": "reaction_10057695", "reactome": "R-BTA-1306972", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057690", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10086415": { "compartment": "compartment_70101", "id": "reaction_10086415", "reactome": "R-BTA-8934465", "name": "SHC1 binds PTPN12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084846", "species_10086408" ], "products": [ "species_10086413" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068950", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1M0B4", "ENSBTAT00000068950" ] }, "reaction_10057139": { "compartment": "compartment_876", "id": "reaction_10057139", "reactome": "R-BTA-1250195", "name": "SHC1 phosphorylation by ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057134" ], "products": [ "species_29370", "species_10057136" ], "modifiers": [ [ "species_10057134", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10083483": { "compartment": "compartment_70101", "id": "reaction_10083483", "reactome": "R-BTA-8848005", "name": "ERBB2 promotes PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083475", "species_113592" ], "products": [ "species_29370", "species_10057132", "species_10083480" ], "modifiers": [ [ "species_10083475", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083477": { "compartment": "compartment_876", "id": "reaction_10083477", "reactome": "R-BTA-8847995", "name": "Activated ERBB2 binds PTK6 (BRK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083473", "species_10057132" ], "products": [ "species_10083475" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10057700": { "compartment": "compartment_876", "id": "reaction_10057700", "reactome": "R-BTA-1306979", "name": "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057697", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077601": { "compartment": "compartment_70101", "id": "reaction_10077601", "reactome": "R-BTA-6785636", "name": "Phosphorylated ERBB2 heterodimers bind MEMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057132", "species_10077597" ], "products": [ "species_10077599" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000085928", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077605": { "compartment": "compartment_70101", "id": "reaction_10077605", "reactome": "R-BTA-6785648", "name": "MEMO1 binds RHOA:GTP:DIAPH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073537", "species_10077599" ], "products": [ "species_10077603" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10084849": { "compartment": "compartment_876", "id": "reaction_10084849", "reactome": "R-BTA-8863804", "name": "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10057132" ], "products": [ "species_29372", "species_10084842" ], "modifiers": [ [ "species_10084846", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000068950" ] }, "reaction_10061458": { "compartment": "compartment_876", "id": "reaction_10061458", "reactome": "R-BTA-1963563", "name": "MATK (CSK homologous kinase) binds phosphorylated ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061454", "species_10057132" ], "products": [ "species_10061456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069379", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q58D16", "ENSBTAT00000069379" ] }, "reaction_10057740": { "compartment": "compartment_70101", "id": "reaction_10057740", "reactome": "R-BTA-1358795", "name": "Deubiquitination of RNF41 by P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057737" ], "products": [ "species_10033408", "species_10055232", "species_10057726" ], "modifiers": [ [ "species_10057737", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057742": { "compartment": "compartment_70101", "id": "reaction_10057742", "reactome": "R-BTA-1358797", "name": "Ubiquitinated RNF41 binds P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057726", "species_10057709" ], "products": [ "species_10057737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057744": { "compartment": "compartment_70101", "id": "reaction_10057744", "reactome": "R-BTA-1358801", "name": "ERBB3 binds RNF41 ubiquitin ligase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055232", "species_10057066" ], "products": [ "species_10057714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087037", "ENSBTAT00000013790", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057712": { "compartment": "compartment_70101", "id": "reaction_10057712", "reactome": "R-BTA-1358789", "name": "Self-ubiquitination of RNF41", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10055232" ], "products": [ "species_10057709" ], "modifiers": [ [ "species_10055232", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037" ] }, "reaction_10057719": { "compartment": "compartment_70101", "id": "reaction_10057719", "reactome": "R-BTA-1358790", "name": "RNF41 ubiquitinates ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057714", "species_10033408" ], "products": [ "species_10057716", "species_10055232" ], "modifiers": [ [ "species_10057714", "catalyst" ] ], "additional_components": [ "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QR62", "ENSBTAT00000013790", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057735": { "compartment": "compartment_70101", "id": "reaction_10057735", "reactome": "R-BTA-1358792", "name": "RNF41 ubiquitinates activated ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057730", "species_10033408" ], "products": [ "species_10057732", "species_10055232" ], "modifiers": [ [ "species_10057730", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10061492": { "compartment": "compartment_876", "id": "reaction_10061492", "reactome": "R-BTA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10061466" ], "modifiers": [ [ "species_10061489", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10066602": { "compartment": "compartment_70101", "id": "reaction_10066602", "reactome": "R-BTA-3165230", "name": "SLC52A1,2,3 transport RIB from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3165253" ], "products": [ "species_196931" ], "modifiers": [ [ "species_10066599", "catalyst" ], [ "species_73524", "inhibitor" ], [ "species_29386", "inhibitor" ] ], "additional_components": [ "A0A3Q1N6I5", "ENSBTAT00000083852", "Q5E9R1", "ENSBTAT00000084768" ] }, "reaction_10041772": { "compartment": "compartment_70101", "id": "reaction_10041772", "reactome": "R-BTA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10041769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081315" ] }, "reaction_10041790": { "compartment": "compartment_70101", "id": "reaction_10041790", "reactome": "R-BTA-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29386" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10041787", "catalyst" ] ], "additional_components": [ "F1MNS5", "ENSBTAT00000061365" ] }, "reaction_10041781": { "compartment": "compartment_70101", "id": "reaction_10041781", "reactome": "R-BTA-196950", "name": "2xTRAP hydrolyzes FMN to RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73524" ], "products": [ "species_29372", "species_196931" ], "modifiers": [ [ "species_10041778", "catalyst" ] ], "additional_components": [ "E1B8A0", "ENSBTAT00000006339" ] }, "reaction_10041799": { "compartment": "compartment_70101", "id": "reaction_10041799", "reactome": "R-BTA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10041796", "catalyst" ] ], "additional_components": [ "species_29926", "F6R223", "ENSBTAT00000025762" ] }, "reaction_10056185": { "compartment": "compartment_876", "id": "reaction_10056185", "reactome": "R-BTA-1112602", "name": "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056174" ], "products": [ "species_10056180", "species_29370" ], "modifiers": [ [ "species_10056174", "catalyst" ], [ "species_10056183", "inhibitor" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056123": { "compartment": "compartment_876", "id": "reaction_10056123", "reactome": "R-BTA-1067659", "name": "Assembly of hexameric IL-6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056119" ], "products": [ "species_10056121" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056188": { "compartment": "compartment_876", "id": "reaction_10056188", "reactome": "R-BTA-1112604", "name": "Phosphorylated STATs are released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180" ], "products": [ "species_10056166", "species_10051764" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342" ] }, "reaction_10056127": { "compartment": "compartment_876", "id": "reaction_10056127", "reactome": "R-BTA-1067667", "name": "IL6 binds IL6R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_10056094" ], "products": [ "species_10056115" ], "modifiers": [ [ "species_10056125", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056176": { "compartment": "compartment_876", "id": "reaction_10056176", "reactome": "R-BTA-1112565", "name": "Tyrosine phosphorylated IL6ST binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10046556" ], "products": [ "species_10056174" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056178": { "compartment": "compartment_70101", "id": "reaction_10056178", "reactome": "R-BTA-1112587", "name": "STAT1 and STAT3 dimers translocate to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056201": { "compartment": "compartment_876", "id": "reaction_10056201", "reactome": "R-BTA-1112708", "name": "PTPN11 binds p-Y759-IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10040231" ], "products": [ "species_10056190" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056168": { "compartment": "compartment_876", "id": "reaction_10056168", "reactome": "R-BTA-1112510", "name": "IL6ST is tyrosine phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056149", "species_113592" ], "products": [ "species_10056166", "species_29370" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056170": { "compartment": "compartment_876", "id": "reaction_10056170", "reactome": "R-BTA-1112514", "name": "JAK activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056121" ], "products": [ "species_10056149", "species_29370" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056205": { "compartment": "compartment_876", "id": "reaction_10056205", "reactome": "R-BTA-1112727", "name": "Serine phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180", "species_113592" ], "products": [ "species_29370", "species_10056203" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056172": { "compartment": "compartment_70101", "id": "reaction_10056172", "reactome": "R-BTA-1112538", "name": "Phosphorylated STAT1, STAT3 form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051764" ], "products": [ "species_10051766" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056207": { "compartment": "compartment_876", "id": "reaction_10056207", "reactome": "R-BTA-1112755", "name": "SOCS3 binds IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10051731" ], "products": [ "species_10056183" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000011106", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056110": { "compartment": "compartment_984", "id": "reaction_10056110", "reactome": "R-BTA-1067651", "name": "IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056100" ], "products": [ "species_10056104" ], "modifiers": [ [ "species_10056108", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10091747": { "compartment": "compartment_984", "id": "reaction_10091747", "reactome": "R-BTA-9681294", "name": "IL6R binds IL6R inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_9715042" ], "products": [ "species_10056125" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056130": { "compartment": "compartment_984", "id": "reaction_10056130", "reactome": "R-BTA-1067676", "name": "IL6:IL6R-2 binds IL6ST-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056100", "species_10056106" ], "products": [ "species_10056108" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056194": { "compartment": "compartment_876", "id": "reaction_10056194", "reactome": "R-BTA-1112690", "name": "PTPN11 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10056190" ], "products": [ "species_10056192" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10056132": { "compartment": "compartment_876", "id": "reaction_10056132", "reactome": "R-BTA-1067688", "name": "IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056115" ], "products": [ "species_10056117" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056199": { "compartment": "compartment_876", "id": "reaction_10056199", "reactome": "R-BTA-1112703", "name": "PTPN11 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056190" ], "products": [ "species_10056196", "species_29370" ], "modifiers": [ [ "species_10056190", "catalyst" ] ], "additional_components": [ "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056102": { "compartment": "compartment_984", "id": "reaction_10056102", "reactome": "R-BTA-1067640", "name": "IL6 binds IL6R-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056098", "species_10056094" ], "products": [ "species_10056100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10087338": { "compartment": "compartment_984", "id": "reaction_10087338", "reactome": "R-BTA-8940998", "name": "IL36RN, IL1F10 bind IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087334", "species_10083514" ], "products": [ "species_10087336" ], "modifiers": [], "additional_components": [ "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10083522": { "compartment": "compartment_984", "id": "reaction_10083522", "reactome": "R-BTA-8848316", "name": "IL36 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083510", "species_10083514" ], "products": [ "species_10083516" ], "modifiers": [ [ "species_10083520", "inhibitor" ] ], "additional_components": [ "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000023970" ] }, "reaction_10050024": { "compartment": "compartment_70101", "id": "reaction_10050024", "reactome": "R-BTA-448678", "name": "CTSG cleaves CASP1(1-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050013" ], "products": [ "species_10050007", "species_10050005", "species_10050017", "species_10050015" ], "modifiers": [ [ "species_10050021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000054741" ] }, "reaction_10050011": { "compartment": "compartment_70101", "id": "reaction_10050011", "reactome": "R-BTA-448673", "name": "Formation of caspase-1 p10/p20 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050007", "species_10050005" ], "products": [ "species_10050009" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10050028": { "compartment": "compartment_70101", "id": "reaction_10050028", "reactome": "R-BTA-448702", "name": "Caspase-1 active tetramer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050009" ], "products": [ "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089595": { "compartment": "compartment_984", "id": "reaction_10089595", "reactome": "R-BTA-9007901", "name": "IL1F10 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332", "species_10083514" ], "products": [ "species_10089593" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10089597": { "compartment": "compartment_984", "id": "reaction_10089597", "reactome": "R-BTA-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037699", "species_113592" ], "products": [ "species_29370", "species_10039514" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10089591": { "compartment": "compartment_984", "id": "reaction_10089591", "reactome": "R-BTA-9007882", "name": "IL1F10 is cleaved", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332" ], "products": [ "species_10089589", "species_10089587" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000023975", "ENSBTAT00000023975" ] }, "reaction_10089625": { "compartment": "compartment_70101", "id": "reaction_10089625", "reactome": "R-BTA-9008696", "name": "IL37(?-218) translocates from the cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089617" ], "products": [ "species_10089623" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089819": { "compartment": "compartment_70101", "id": "reaction_10089819", "reactome": "R-BTA-9012556", "name": "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089810" ], "products": [ "species_10089816" ], "modifiers": [ [ "species_10089810", "catalyst" ] ], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10089615": { "compartment": "compartment_70101", "id": "reaction_10089615", "reactome": "R-BTA-9008684", "name": "TBK1 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_113592" ], "products": [ "species_29370", "species_10089613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000023134" ] }, "reaction_10083537": { "compartment": "compartment_984", "id": "reaction_10083537", "reactome": "R-BTA-8848335", "name": "IL37 binds IL18R1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083527", "species_10083531" ], "products": [ "species_10083535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001371", "ENSBTAT00000029311", "E1BLE5", "ENSBTAT00000029311", "F1MJ29", "ENSBTAT00000001371" ] }, "reaction_10089843": { "compartment": "compartment_70101", "id": "reaction_10089843", "reactome": "R-BTA-9012689", "name": "IL37(1-?) and IL37 (?-) dissocates from IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089816" ], "products": [ "species_10089814", "species_10089617", "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "ENSBTAT00000029311", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089621": { "compartment": "compartment_70101", "id": "reaction_10089621", "reactome": "R-BTA-9008694", "name": "IL37, IL37(?-218) translocates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619" ], "products": [ "species_10083531" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089812": { "compartment": "compartment_70101", "id": "reaction_10089812", "reactome": "R-BTA-9012542", "name": "IL37 binds 2x(CASP1(120-197):CASP1(317-404))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619", "species_10050026" ], "products": [ "species_10089810" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10049721": { "compartment": "compartment_876", "id": "reaction_10049721", "reactome": "R-BTA-445757", "name": "IL1 receptor antagonist protein binds Interleukin 1 receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049717", "species_10049713" ], "products": [ "species_10049719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087066", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "A0A3Q1MKE9", "ENSBTAT00000087066" ] }, "reaction_10043867": { "compartment": "compartment_70101", "id": "reaction_10043867", "reactome": "R-BTA-209087", "name": "IKBA is phosphorylated by Phospho IKKB kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043854" ], "products": [ "species_10043858", "species_29370" ], "modifiers": [ [ "species_10043864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022183", "ENSBTAT00000022183", "ENSBTAT00000009995" ] }, "reaction_10091757": { "compartment": "compartment_984", "id": "reaction_10091757", "reactome": "R-BTA-9681763", "name": "IL1R1 binds IL1R1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9681804", "species_10049707" ], "products": [ "species_10091755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006938", "F1ML75", "ENSBTAT00000006938" ] }, "reaction_10050428": { "compartment": "compartment_70101", "id": "reaction_10050428", "reactome": "R-BTA-450827", "name": "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050418", "species_113592" ], "products": [ "species_29370", "species_10050425" ], "modifiers": [ [ "species_10050418", "catalyst" ] ], "additional_components": [ "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10050420": { "compartment": "compartment_70101", "id": "reaction_10050420", "reactome": "R-BTA-450690", "name": "hp-IRAK1,hp-IRAK4 bind Pellino1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050416", "species_10050412" ], "products": [ "species_10050418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067567", "ENSBTAT00000028115", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10051095": { "compartment": "compartment_70101", "id": "reaction_10051095", "reactome": "R-BTA-507719", "name": "p62:MEKK3 binds to TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051091", "species_10039473" ], "products": [ "species_10051093" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015" ] }, "reaction_10085017": { "compartment": "compartment_7660", "id": "reaction_10085017", "reactome": "R-BTA-8865613", "name": "BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084951", "species_10085013" ], "products": [ "species_10085015" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018087", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTQ0", "ENSBTAT00000018087" ] }, "reaction_10091731": { "compartment": "compartment_70101", "id": "reaction_10091731", "reactome": "R-BTA-9679028", "name": "JAK3 binds JAK3 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_9678772" ], "products": [ "species_10091729" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10089251": { "compartment": "compartment_876", "id": "reaction_10089251", "reactome": "R-BTA-8983059", "name": "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089244" ], "products": [ "species_29370", "species_10089248" ], "modifiers": [ [ "species_10089244", "catalyst" ] ], "additional_components": [ "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10089253": { "compartment": "compartment_984", "id": "reaction_10089253", "reactome": "R-BTA-8983061", "name": "TSLP binds CRLF2:IL7R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089234", "species_10089240" ], "products": [ "species_10089242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10087787": { "compartment": "compartment_70101", "id": "reaction_10087787", "reactome": "R-BTA-8950731", "name": "CRLF1:IL27 translocates to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087772" ], "products": [ "species_10087785" ], "modifiers": [], "additional_components": [ "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10049946": { "compartment": "compartment_984", "id": "reaction_10049946", "reactome": "R-BTA-448421", "name": "Interleukin-27 translocates from the ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049938" ], "products": [ "species_10049944" ], "modifiers": [], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046" ] }, "reaction_10087726": { "compartment": "compartment_876", "id": "reaction_10087726", "reactome": "R-BTA-8950340", "name": "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087711" ], "products": [ "species_29370", "species_10087723" ], "modifiers": [ [ "species_10087711", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087774": { "compartment": "compartment_70101", "id": "reaction_10087774", "reactome": "R-BTA-8950504", "name": "IL27 binds CRLF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087770", "species_10087768" ], "products": [ "species_10087772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083936", "ENSBTAT00000074594", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10087793": { "compartment": "compartment_876", "id": "reaction_10087793", "reactome": "R-BTA-8950766", "name": "IL27RA dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049962" ], "products": [ "species_10087791" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022524", "A5D7S4", "ENSBTAT00000022524" ] }, "reaction_10049970": { "compartment": "compartment_984", "id": "reaction_10049970", "reactome": "R-BTA-448427", "name": "Interleukin-27 binds Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10049964", "species_10049944" ], "products": [ "species_10049966" ], "modifiers": [ [ "species_10049968", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "ENSBTAT00000022524" ] }, "reaction_10087671": { "compartment": "compartment_984", "id": "reaction_10087671", "reactome": "R-BTA-8950210", "name": "Interleukin-27 dissociates from Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049966" ], "products": [ "species_10049958", "species_10049964", "species_10049944" ], "modifiers": [ [ "species_10049940", "inhibitor" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "ENSBTAT00000083936" ] }, "reaction_10087783": { "compartment": "compartment_876", "id": "reaction_10087783", "reactome": "R-BTA-8950537", "name": "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049966" ], "products": [ "species_29370", "species_10087711" ], "modifiers": [ [ "species_10049966", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10087766": { "compartment": "compartment_70101", "id": "reaction_10087766", "reactome": "R-BTA-8950485", "name": "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087736" ], "products": [ "species_10087734", "species_29370" ], "modifiers": [ [ "species_10087736", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089321": { "compartment": "compartment_876", "id": "reaction_10089321", "reactome": "R-BTA-8983834", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089313" ], "products": [ "species_10089319", "species_29370" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089329": { "compartment": "compartment_876", "id": "reaction_10089329", "reactome": "R-BTA-8983835", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089325" ], "products": [ "species_29370", "species_10089327" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089331": { "compartment": "compartment_876", "id": "reaction_10089331", "reactome": "R-BTA-8983841", "name": "STAT1 associates with IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046556", "species_10089323" ], "products": [ "species_10089325" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10087763": { "compartment": "compartment_70101", "id": "reaction_10087763", "reactome": "R-BTA-8950453", "name": "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087752" ], "products": [ "species_29370", "species_10087760" ], "modifiers": [ [ "species_10087752", "catalyst" ] ], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089333": { "compartment": "compartment_876", "id": "reaction_10089333", "reactome": "R-BTA-8983845", "name": "p-STAT1 dissociates from IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089327" ], "products": [ "species_10087758", "species_10089323" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087780": { "compartment": "compartment_70101", "id": "reaction_10087780", "reactome": "R-BTA-8950522", "name": "p-STAT1:p-STAT4 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087776" ], "products": [ "species_10087778" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10049928": { "compartment": "compartment_984", "id": "reaction_10049928", "reactome": "R-BTA-447130", "name": "Interleukin-23 binds interleukin-23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049924", "species_10049904", "species_10049914" ], "products": [ "species_10049926" ], "modifiers": [], "additional_components": [ "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10087789": { "compartment": "compartment_984", "id": "reaction_10087789", "reactome": "R-BTA-8950741", "name": "IL12B:IL23A translocates from ER lumen to extracellular space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087669" ], "products": [ "species_10049904" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MSN4", "ENSBTAT00000005745", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10087697": { "compartment": "compartment_70101", "id": "reaction_10087697", "reactome": "R-BTA-8950269", "name": "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087690" ], "products": [ "species_29370", "species_10087694" ], "modifiers": [ [ "species_10087690", "catalyst" ] ], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10088498": { "compartment": "compartment_70101", "id": "reaction_10088498", "reactome": "R-BTA-8952749", "name": "STAT4 binds p-Y-IL23R in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087674", "species_10087688" ], "products": [ "species_10087690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10051194": { "compartment": "compartment_70101", "id": "reaction_10051194", "reactome": "R-BTA-508451", "name": "PTK2B is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051187" ], "products": [ "species_10051192" ], "modifiers": [], "additional_components": [ "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857", "A0A3Q1LVP1", "ENSBTAT00000084967" ] }, "reaction_10051196": { "compartment": "compartment_70101", "id": "reaction_10051196", "reactome": "R-BTA-508513", "name": "PTK2B binds JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_10047260" ], "products": [ "species_10051187" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "ENSBTAT00000084967", "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10050527": { "compartment": "compartment_70101", "id": "reaction_10050527", "reactome": "R-BTA-451900", "name": "IL2RB binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050134", "species_10049950" ], "products": [ "species_10050136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074166", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166" ] }, "reaction_10089736": { "compartment": "compartment_70101", "id": "reaction_10089736", "reactome": "R-BTA-9011748", "name": "IL9R binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089732", "species_10049950" ], "products": [ "species_10089734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009944", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MTF9", "ENSBTAT00000009944" ] }, "reaction_10089363": { "compartment": "compartment_70101", "id": "reaction_10089363", "reactome": "R-BTA-8985943", "name": "p-Y701-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089359" ], "products": [ "species_10089361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10050619": { "compartment": "compartment_876", "id": "reaction_10050619", "reactome": "R-BTA-453104", "name": "Phosphorylated SHC1 recruits GRB2:GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050571", "species_10050569" ], "products": [ "species_10050617" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10050623": { "compartment": "compartment_70101", "id": "reaction_10050623", "reactome": "R-BTA-453111", "name": "Phosphorylated SHC recruits GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10050569" ], "products": [ "species_10050621" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10052254": { "compartment": "compartment_876", "id": "reaction_10052254", "reactome": "R-BTA-912527", "name": "SHC1 mediates cytokine-induced phosphorylation of GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050617" ], "products": [ "species_29370", "species_10052252" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10052337": { "compartment": "compartment_70101", "id": "reaction_10052337", "reactome": "R-BTA-913374", "name": "Phosphorylated SHC1 recruits SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052333", "species_10050569" ], "products": [ "species_10052335" ], "modifiers": [], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10052343": { "compartment": "compartment_70101", "id": "reaction_10052343", "reactome": "R-BTA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052339", "species_10035485" ], "products": [ "species_10052341" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529" ] }, "reaction_10089291": { "compartment": "compartment_17940", "id": "reaction_10089291", "reactome": "R-BTA-8983335", "name": "IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255" ], "products": [ "species_10089289" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089311": { "compartment": "compartment_70101", "id": "reaction_10089311", "reactome": "R-BTA-8983384", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089307", "species_10089305" ], "products": [ "species_10089309" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089267": { "compartment": "compartment_70101", "id": "reaction_10089267", "reactome": "R-BTA-8983300", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255", "species_113592" ], "products": [ "species_29370", "species_10089264" ], "modifiers": [ [ "species_10089255", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089269": { "compartment": "compartment_984", "id": "reaction_10089269", "reactome": "R-BTA-8983307", "name": "IL15 binds IL15RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050128", "species_10050124" ], "products": [ "species_10050130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083836", "ENSBTAT00000084366", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089689": { "compartment": "compartment_984", "id": "reaction_10089689", "reactome": "R-BTA-9009485", "name": "IL34:CSF1 binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089685", "species_10077839" ], "products": [ "species_10089687" ], "modifiers": [], "additional_components": [ "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179", "ENSBTAT00000016977", "A7Z067", "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10089691": { "compartment": "compartment_984", "id": "reaction_10089691", "reactome": "R-BTA-9009488", "name": "IL34 binds CSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089683", "species_10049979" ], "products": [ "species_10089685" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076179", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10090027": { "compartment": "compartment_984", "id": "reaction_10090027", "reactome": "R-BTA-9014052", "name": "TXLNA (IL14) binds syntaxin3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090023", "species_10050140" ], "products": [ "species_10090025" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069233", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A3Q1LYB4", "ENSBTAT00000069233" ] }, "reaction_10049983": { "compartment": "compartment_984", "id": "reaction_10049983", "reactome": "R-BTA-448632", "name": "IL34 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049979" ], "products": [ "species_10049981" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664" ] }, "reaction_10090031": { "compartment": "compartment_984", "id": "reaction_10090031", "reactome": "R-BTA-9014074", "name": "TXLNA (IL14) binds syntaxin4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10050140" ], "products": [ "species_10090029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10077843": { "compartment": "compartment_876", "id": "reaction_10077843", "reactome": "R-BTA-6787820", "name": "IL34 dimer binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077839", "species_10049981" ], "products": [ "species_10077841" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A7Z067", "ENSBTAT00000016977" ] }, "reaction_10077945": { "compartment": "compartment_17957", "id": "reaction_10077945", "reactome": "R-BTA-6790038", "name": "Expression of HSP90B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10060767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004364" ] }, "reaction_10077723": { "compartment": "compartment_70101", "id": "reaction_10077723", "reactome": "R-BTA-6786097", "name": "p-Y705-STAT3, p-Y641-STAT6 dimerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077719" ], "products": [ "species_10077721" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077870": { "compartment": "compartment_70101", "id": "reaction_10077870", "reactome": "R-BTA-6788622", "name": "p-Y-STATs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077866" ], "products": [ "species_10077868" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10077633": { "compartment": "compartment_876", "id": "reaction_10077633", "reactome": "R-BTA-6785762", "name": "IL13RA1 binds TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049908", "species_10077629" ], "products": [ "species_10077631" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015532", "ENSBTAT00000025754", "G3X7E9", "ENSBTAT00000025754", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10077874": { "compartment": "compartment_70101", "id": "reaction_10077874", "reactome": "R-BTA-6788623", "name": "p-Y-STATs translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077868" ], "products": [ "species_10077872" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077764": { "compartment": "compartment_70101", "id": "reaction_10077764", "reactome": "R-BTA-6786293", "name": "p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077721" ], "products": [ "species_10077762" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10052302": { "compartment": "compartment_70101", "id": "reaction_10052302", "reactome": "R-BTA-912734", "name": "CBL:CRKL binds RAPGEF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052298", "species_10039707" ], "products": [ "species_10052300" ], "modifiers": [], "additional_components": [ "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052323": { "compartment": "compartment_70101", "id": "reaction_10052323", "reactome": "R-BTA-912790", "name": "CBL binds CRK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052267", "species_10052296" ], "products": [ "species_10052298" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052294": { "compartment": "compartment_70101", "id": "reaction_10052294", "reactome": "R-BTA-912627", "name": "CBL ubiquitinates PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10052269" ], "products": [ "species_10052292" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10051962": { "compartment": "compartment_70101", "id": "reaction_10051962", "reactome": "R-BTA-879934", "name": "Recruitment of SHC1 is mediated by Y593 of the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051923", "species_10035544" ], "products": [ "species_10051960" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10051949": { "compartment": "compartment_70101", "id": "reaction_10051949", "reactome": "R-BTA-879909", "name": "Activation of STAT5a/b by JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051942", "species_113592" ], "products": [ "species_29370", "species_10051946" ], "modifiers": [ [ "species_10051942", "catalyst" ] ], "additional_components": [ "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10052735": { "compartment": "compartment_876", "id": "reaction_10052735", "reactome": "R-BTA-914036", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052238" ], "products": [ "species_10052732" ], "modifiers": [ [ "species_10052238", "catalyst" ] ], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051966": { "compartment": "compartment_876", "id": "reaction_10051966", "reactome": "R-BTA-879942", "name": "The receptor is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051964" ], "products": [ "species_10051921" ], "modifiers": [], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052321": { "compartment": "compartment_70101", "id": "reaction_10052321", "reactome": "R-BTA-912757", "name": "p-S585-IL3RB binds 14-3-3 proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037660", "species_10052317" ], "products": [ "species_10052319" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "P63103", "ENSBTAT00000000289" ] }, "reaction_10051936": { "compartment": "compartment_70101", "id": "reaction_10051936", "reactome": "R-BTA-879907", "name": "Tyrosine kinases phosphorylate the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051923" ], "modifiers": [ [ "species_10051933", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052240": { "compartment": "compartment_70101", "id": "reaction_10052240", "reactome": "R-BTA-909738", "name": "SHP1 and SHP2 bind the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047046", "species_10051923" ], "products": [ "species_10052238" ], "modifiers": [], "additional_components": [ "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051954": { "compartment": "compartment_70101", "id": "reaction_10051954", "reactome": "R-BTA-879910", "name": "JAK2 is phosphorylated, activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051951" ], "modifiers": [ [ "species_10051921", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052325": { "compartment": "compartment_984", "id": "reaction_10052325", "reactome": "R-BTA-913360", "name": "GM-CSF receptor alpha subunit binds GM-CSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050559", "species_10050555" ], "products": [ "species_10050561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002054", "ENSBTAT00000040022", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052327": { "compartment": "compartment_876", "id": "reaction_10052327", "reactome": "R-BTA-913371", "name": "GM-CSF receptor alpha:GM-CSF binds Bc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051911", "species_10050561" ], "products": [ "species_10051917" ], "modifiers": [], "additional_components": [ "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947" ] }, "reaction_10089466": { "compartment": "compartment_70101", "id": "reaction_10089466", "reactome": "R-BTA-8987084", "name": "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089459", "species_113592" ], "products": [ "species_10089463", "species_29370" ], "modifiers": [ [ "species_10089459", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089530": { "compartment": "compartment_70101", "id": "reaction_10089530", "reactome": "R-BTA-8987202", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089527", "species_113592" ], "products": [ "species_29370", "species_10089450" ], "modifiers": [ [ "species_10089527", "catalyst" ] ], "additional_components": [ "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10089523": { "compartment": "compartment_70101", "id": "reaction_10089523", "reactome": "R-BTA-8987179", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089520" ], "products": [ "species_10089490", "species_29370" ], "modifiers": [ [ "species_10089520", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089427": { "compartment": "compartment_459", "id": "reaction_10089427", "reactome": "R-BTA-8986985", "name": "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089417" ], "products": [ "species_29370", "species_10089424" ], "modifiers": [ [ "species_10089417", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089431": { "compartment": "compartment_70101", "id": "reaction_10089431", "reactome": "R-BTA-8987007", "name": "p-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087758" ], "products": [ "species_10089429" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089480": { "compartment": "compartment_70101", "id": "reaction_10089480", "reactome": "R-BTA-8987097", "name": "IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089476", "species_10046556" ], "products": [ "species_10089478" ], "modifiers": [], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089453": { "compartment": "compartment_70101", "id": "reaction_10089453", "reactome": "R-BTA-8987040", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089450" ], "products": [ "species_10089413", "species_29370" ], "modifiers": [ [ "species_10089450", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825" ] }, "reaction_10089516": { "compartment": "compartment_70101", "id": "reaction_10089516", "reactome": "R-BTA-8987150", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089478", "species_113592" ], "products": [ "species_29370", "species_10089513" ], "modifiers": [ [ "species_10089478", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089455": { "compartment": "compartment_70101", "id": "reaction_10089455", "reactome": "R-BTA-8987043", "name": "IL22RA1 binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050036", "species_10049950" ], "products": [ "species_10050038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001455", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089536": { "compartment": "compartment_70101", "id": "reaction_10089536", "reactome": "R-BTA-8987218", "name": "p-STAT1 dimer translocates from the cytosol to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089429" ], "products": [ "species_10089534" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089538": { "compartment": "compartment_70101", "id": "reaction_10089538", "reactome": "R-BTA-8987220", "name": "IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089518", "species_10089484" ], "products": [ "species_10089520" ], "modifiers": [], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089442": { "compartment": "compartment_70101", "id": "reaction_10089442", "reactome": "R-BTA-8987012", "name": "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089435" ], "products": [ "species_29370", "species_10089439" ], "modifiers": [ [ "species_10089435", "catalyst" ] ], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455", "F1MJR4", "ENSBTAT00000001455", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089506": { "compartment": "compartment_70101", "id": "reaction_10089506", "reactome": "R-BTA-8987120", "name": "JAK1 binds IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10049999" ], "products": [ "species_10050001" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000001456", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089540": { "compartment": "compartment_70101", "id": "reaction_10089540", "reactome": "R-BTA-8987266", "name": "IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089415", "species_10089413" ], "products": [ "species_10089417" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089444": { "compartment": "compartment_70101", "id": "reaction_10089444", "reactome": "R-BTA-8987033", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089424" ], "products": [ "species_10089413", "species_10089422" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089511": { "compartment": "compartment_70101", "id": "reaction_10089511", "reactome": "R-BTA-8987129", "name": "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089508", "species_113592" ], "products": [ "species_10089476", "species_29370" ], "modifiers": [ [ "species_10089508", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089446": { "compartment": "compartment_70101", "id": "reaction_10089446", "reactome": "R-BTA-8987039", "name": "JAK1 binds IL20RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10050044" ], "products": [ "species_10050046" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000066507", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10050054": { "compartment": "compartment_876", "id": "reaction_10050054", "reactome": "R-BTA-448744", "name": "IL20RA binds IL20RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050032", "species_10050046" ], "products": [ "species_10050048" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089542": { "compartment": "compartment_70101", "id": "reaction_10089542", "reactome": "R-BTA-8987270", "name": "p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089513" ], "products": [ "species_10089476", "species_10087758" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342" ] }, "reaction_10061449": { "compartment": "compartment_70101", "id": "reaction_10061449", "reactome": "R-BTA-1912382", "name": "Mature NOTCH heterodimer traffics to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061434" ], "products": [ "species_10061443" ], "modifiers": [ [ "species_10061447", "inhibitor" ] ], "additional_components": [ "G3X812", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "ENSBTAT00000084118" ] }, "reaction_10090834": { "compartment": "compartment_13231", "id": "reaction_10090834", "reactome": "R-BTA-9604308", "name": "NICD4 traffics to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090824" ], "products": [ "species_10044414" ], "modifiers": [ [ "species_10090832", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000050083", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "P63103", "ENSBTAT00000000289" ] }, "reaction_10078393": { "compartment": "compartment_5460", "id": "reaction_10078393", "reactome": "R-BTA-6793590", "name": "LIPT2 transfers octanoyl group to GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078383", "species_10076429" ], "products": [ "species_10038774", "species_10078386" ], "modifiers": [ [ "species_10078390", "catalyst" ] ], "additional_components": [ "CHEBI:25650", "G3X6L0", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000010820" ] }, "reaction_10052056": { "compartment": "compartment_5460", "id": "reaction_10052056", "reactome": "R-BTA-904864", "name": "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_904849", "species_379697" ], "products": [ "species_159549", "species_113557" ], "modifiers": [ [ "species_10052053", "catalyst" ] ], "additional_components": [ "F1MLG7", "ENSBTAT00000010113" ] }, "reaction_10047019": { "compartment": "compartment_17951", "id": "reaction_10047019", "reactome": "R-BTA-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389822" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078701": { "compartment": "compartment_70101", "id": "reaction_10078701", "reactome": "R-BTA-6798317", "name": "GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_29424" ], "products": [ "species_5359017", "species_71285" ], "modifiers": [ [ "species_10078698", "catalyst" ] ], "additional_components": [ "A0A3Q1LMP5", "ENSBTAT00000079667", "A0A3Q1M678", "ENSBTAT00000080669" ] }, "reaction_10047022": { "compartment": "compartment_17951", "id": "reaction_10047022", "reactome": "R-BTA-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_141343", "species_389678" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078366": { "compartment": "compartment_5460", "id": "reaction_10078366", "reactome": "R-BTA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078353", "species_10076427" ], "products": [ "species_10078359", "species_10076429" ], "modifiers": [ [ "species_10078363", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000005171" ] }, "reaction_10077458": { "compartment": "compartment_5460", "id": "reaction_10077458", "reactome": "R-BTA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10078402": { "compartment": "compartment_5460", "id": "reaction_10078402", "reactome": "R-BTA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10078386", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10076427" ], "modifiers": [ [ "species_10078399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "ENSBTAT00000008936", "Q5BIP7", "ENSBTAT00000019299", "CHEBI:49883" ] }, "reaction_10076441": { "compartment": "compartment_5460", "id": "reaction_10076441", "reactome": "R-BTA-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10076427" ], "products": [ "species_10076431", "species_29376" ], "modifiers": [ [ "species_10076438", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "P20821", "ENSBTAT00000008936", "CHEBI:14949", "E1BJQ1", "ENSBTAT00000036700" ] }, "reaction_10076459": { "compartment": "compartment_5460", "id": "reaction_10076459", "reactome": "R-BTA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10076443" ], "products": [ "species_113529", "species_29362", "species_10076427" ], "modifiers": [ [ "species_10076456", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000008936", "species_113596", "F1N206", "ENSBTAT00000033787" ] }, "reaction_10076450": { "compartment": "compartment_5460", "id": "reaction_10076450", "reactome": "R-BTA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10076431" ], "products": [ "species_5693978", "species_5693984", "species_10076443" ], "modifiers": [ [ "species_10076447", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:14949", "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000002992" ] }, "reaction_10051737": { "compartment": "compartment_70101", "id": "reaction_10051737", "reactome": "R-BTA-873918", "name": "Transphosphorylation of JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_113592" ], "products": [ "species_29370", "species_10051722" ], "modifiers": [ [ "species_10051716", "catalyst" ], [ "species_10043836", "inhibitor" ], [ "species_10051735", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "ENSBTAT00000077529", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10091723": { "compartment": "compartment_70101", "id": "reaction_10091723", "reactome": "R-BTA-9678561", "name": "IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678984", "species_10051743" ], "products": [ "species_10051778" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10051771": { "compartment": "compartment_70101", "id": "reaction_10051771", "reactome": "R-BTA-873922", "name": "Phosphorylation of STAT1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051760", "species_113592" ], "products": [ "species_29370", "species_10051768" ], "modifiers": [ [ "species_10051760", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051786": { "compartment": "compartment_70101", "id": "reaction_10051786", "reactome": "R-BTA-873927", "name": "Release of STAT1 dimer from active receptor unit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051784" ], "products": [ "species_10051756", "species_10051690" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051774": { "compartment": "compartment_70101", "id": "reaction_10051774", "reactome": "R-BTA-873924", "name": "Phosphorylation of IFNGR1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051722" ], "products": [ "species_29370", "species_10051756" ], "modifiers": [ [ "species_10051722", "catalyst" ] ], "additional_components": [ "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051696": { "compartment": "compartment_13231", "id": "reaction_10051696", "reactome": "R-BTA-873917", "name": "Translocation of STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051690" ], "products": [ "species_10051694" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10052067": { "compartment": "compartment_70101", "id": "reaction_10052067", "reactome": "R-BTA-909552", "name": "Phosphorylation of STAT1 at Ser727", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051768" ], "products": [ "species_29370", "species_10051784" ], "modifiers": [ [ "species_10052064", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10051762": { "compartment": "compartment_70101", "id": "reaction_10051762", "reactome": "R-BTA-873921", "name": "Binding of STAT1 to p-IFNGR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051758", "species_10051756" ], "products": [ "species_10051760" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051818": { "compartment": "compartment_7660", "id": "reaction_10051818", "reactome": "R-BTA-877281", "name": "PIAS1 binds p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051814", "species_10051796", "species_10051694" ], "products": [ "species_10051816" ], "modifiers": [], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "ENSBTAT00000083334", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ML58", "ENSBTAT00000083334", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456" ] }, "reaction_10055967": { "compartment": "compartment_7660", "id": "reaction_10055967", "reactome": "R-BTA-997326", "name": "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10051694" ], "products": [ "species_113550", "species_10055960" ], "modifiers": [ [ "species_10055964", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "ENSBTAT00000074168" ] }, "reaction_10051792": { "compartment": "compartment_70101", "id": "reaction_10051792", "reactome": "R-BTA-877269", "name": "SOCS-1 and SOCS-3 binds to p-JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_10051733" ], "products": [ "species_10051735" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051780": { "compartment": "compartment_984", "id": "reaction_10051780", "reactome": "R-BTA-873926", "name": "IFNG dimer binds IFNGR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051702", "species_10051743" ], "products": [ "species_10051745" ], "modifiers": [ [ "species_10051778", "inhibitor" ], [ "species_10051776", "inhibitor" ] ], "additional_components": [ "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051748": { "compartment": "compartment_70101", "id": "reaction_10051748", "reactome": "R-BTA-873919", "name": "Phosphorylation of JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051745" ], "products": [ "species_10051716", "species_29370" ], "modifiers": [ [ "species_10051745", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10078682": { "compartment": "compartment_876", "id": "reaction_10078682", "reactome": "R-BTA-6798258", "name": "PRTPRF, PTPRS, PTPRD bind LRRC4B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078678", "species_10046864" ], "products": [ "species_10078680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000043330", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "E1BPK8", "ENSBTAT00000043330" ] }, "reaction_10078674": { "compartment": "compartment_876", "id": "reaction_10078674", "reactome": "R-BTA-6798257", "name": "PTPRS binds NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046862", "species_10078670" ], "products": [ "species_10078672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074444", "ENSBTAT00000064547", "G3N3T6", "ENSBTAT00000064547", "A0A3Q1MZF8", "ENSBTAT00000074444" ] }, "reaction_10046868": { "compartment": "compartment_70101", "id": "reaction_10046868", "reactome": "R-BTA-388824", "name": "PTPRF, PTPRS, PTPRD bind Liprins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046854", "species_10046864" ], "products": [ "species_10046866" ], "modifiers": [], "additional_components": [ "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454" ] }, "reaction_10078566": { "compartment": "compartment_876", "id": "reaction_10078566", "reactome": "R-BTA-6797803", "name": "PTPRD binds SLITRK1-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078562", "species_10046858" ], "products": [ "species_10078564" ], "modifiers": [], "additional_components": [ "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827", "ENSBTAT00000066459", "A0A3Q1M422", "ENSBTAT00000066459", "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827" ] }, "reaction_10034944": { "compartment": "compartment_70101", "id": "reaction_10034944", "reactome": "R-BTA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10034941", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10036903": { "compartment": "compartment_70101", "id": "reaction_10036903", "reactome": "R-BTA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10034933", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10076792": { "compartment": "compartment_70101", "id": "reaction_10076792", "reactome": "R-BTA-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694568", "species_29356" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10076789", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022154" ] }, "reaction_10059002": { "compartment": "compartment_12045", "id": "reaction_10059002", "reactome": "R-BTA-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059853": { "compartment": "compartment_984", "id": "reaction_10059853", "reactome": "R-BTA-1602398", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602375", "species_109276" ], "products": [ "species_1602372", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10059004": { "compartment": "compartment_12045", "id": "reaction_10059004", "reactome": "R-BTA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10084526": { "compartment": "compartment_70101", "id": "reaction_10084526", "reactome": "R-BTA-8858298", "name": "HRASLS transfer acyl group from PC to PE to form NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_1500581" ], "products": [ "species_5694568", "species_6814253" ], "modifiers": [ [ "species_10084523", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451" ] }, "reaction_10058899": { "compartment": "compartment_12045", "id": "reaction_10058899", "reactome": "R-BTA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058885": { "compartment": "compartment_12045", "id": "reaction_10058885", "reactome": "R-BTA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058980": { "compartment": "compartment_12045", "id": "reaction_10058980", "reactome": "R-BTA-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10058977", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10046888": { "compartment": "compartment_876", "id": "reaction_10046888", "reactome": "R-BTA-388828", "name": "PD-1 binds B7DC and B7H1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046882", "species_10046872" ], "products": [ "species_10046884" ], "modifiers": [ [ "species_10046886", "inhibitor" ] ], "additional_components": [ "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165", "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10091743": { "compartment": "compartment_876", "id": "reaction_10091743", "reactome": "R-BTA-9679421", "name": "PDCD1 binds PDCD1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679406", "species_10046872" ], "products": [ "species_10046886" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10064439": { "compartment": "compartment_70101", "id": "reaction_10064439", "reactome": "R-BTA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10064584": { "compartment": "compartment_70101", "id": "reaction_10064584", "reactome": "R-BTA-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_2162081", "species_73473" ], "modifiers": [ [ "species_10034181", "catalyst" ] ], "additional_components": [ "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10075063": { "compartment": "compartment_70101", "id": "reaction_10075063", "reactome": "R-BTA-5686073", "name": "GRB2-1:SOS1 binds p-3Y-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050549", "species_10035491" ], "products": [ "species_10075061" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10086241": { "compartment": "compartment_7660", "id": "reaction_10086241", "reactome": "R-BTA-8878220", "name": "RUNX3 binds the NOTCH1 coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10086237" ], "products": [ "species_10086239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10072913": { "compartment": "compartment_876", "id": "reaction_10072913", "reactome": "R-BTA-5654148", "name": "p-4Y-PLCG1 dissociates from activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072911" ], "products": [ "species_10043237", "species_10065265" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072944": { "compartment": "compartment_70101", "id": "reaction_10072944", "reactome": "R-BTA-5654222", "name": "Activated FGFR3 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072941" ], "products": [ "species_29370", "species_10072911" ], "modifiers": [ [ "species_10072941", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10072946": { "compartment": "compartment_876", "id": "reaction_10072946", "reactome": "R-BTA-5654224", "name": "Activated FGFR3 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065265", "species_10061098" ], "products": [ "species_10072941" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10073152": { "compartment": "compartment_70101", "id": "reaction_10073152", "reactome": "R-BTA-5654634", "name": "Activated FGFR3 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073138", "species_113592" ], "products": [ "species_29370", "species_10073149" ], "modifiers": [ [ "species_10073138", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073140": { "compartment": "compartment_70101", "id": "reaction_10073140", "reactome": "R-BTA-5654625", "name": "Activated FGFR3 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065265" ], "products": [ "species_10073138" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073156": { "compartment": "compartment_876", "id": "reaction_10073156", "reactome": "R-BTA-5654646", "name": "Activated FGFR3:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073149" ], "products": [ "species_10073154" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073159": { "compartment": "compartment_70101", "id": "reaction_10073159", "reactome": "R-BTA-5654647", "name": "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073154", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073234": { "compartment": "compartment_70101", "id": "reaction_10073234", "reactome": "R-BTA-5654709", "name": "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065273", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073145": { "compartment": "compartment_876", "id": "reaction_10073145", "reactome": "R-BTA-5654631", "name": "Activated FGFR3 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073142", "species_113592" ], "products": [ "species_10065269", "species_29370" ], "modifiers": [ [ "species_10073142", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073019": { "compartment": "compartment_70101", "id": "reaction_10073019", "reactome": "R-BTA-5654413", "name": "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073016", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073147": { "compartment": "compartment_876", "id": "reaction_10073147", "reactome": "R-BTA-5654633", "name": "Activated FGFR3:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065267" ], "products": [ "species_10073142" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073021": { "compartment": "compartment_70101", "id": "reaction_10073021", "reactome": "R-BTA-5654416", "name": "Activated FGFR3:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065267" ], "products": [ "species_10073016" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10087376": { "compartment": "compartment_70101", "id": "reaction_10087376", "reactome": "R-BTA-8941628", "name": "Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065269", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073011": { "compartment": "compartment_876", "id": "reaction_10073011", "reactome": "R-BTA-5654408", "name": "Activated FGFR3 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073006" ], "products": [ "species_29370", "species_10065267" ], "modifiers": [ [ "species_10073006", "catalyst" ], [ "species_10073009", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073014": { "compartment": "compartment_70101", "id": "reaction_10073014", "reactome": "R-BTA-5654409", "name": "Activated FGFR3 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065265", "species_10072959" ], "products": [ "species_10073006" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10062984": { "compartment": "compartment_20699", "id": "reaction_10062984", "reactome": "R-BTA-2022860", "name": "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062948", "species_741440" ], "products": [ "species_742343", "species_10062971" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063610": { "compartment": "compartment_20699", "id": "reaction_10063610", "reactome": "R-BTA-2076508", "name": "HS2ST1 sulfates IdoA at C2 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063045", "species_741440" ], "products": [ "species_742343", "species_10063068" ], "modifiers": [ [ "species_10063607", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "ENSBTAT00000086518" ] }, "reaction_10063633": { "compartment": "compartment_20699", "id": "reaction_10063633", "reactome": "R-BTA-2076611", "name": "HS3STs sulfate GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063630", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VD21", "ENSBTAT00000085321", "E1B729", "ENSBTAT00000025630", "E1BKQ1", "ENSBTAT00000023123", "E1BNJ7", "ENSBTAT00000044024", "E1BP03", "ENSBTAT00000010350" ] }, "reaction_10063216": { "compartment": "compartment_17963", "id": "reaction_10063216", "reactome": "R-BTA-2024108", "name": "Some HSPGs are secreted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063132" ], "products": [ "species_10063214" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452" ] }, "reaction_10063603": { "compartment": "compartment_20699", "id": "reaction_10063603", "reactome": "R-BTA-2076419", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063114" ], "products": [ "species_742343", "species_10063130" ], "modifiers": [ [ "species_10063600", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LS54", "ENSBTAT00000078465", "A0A3Q1LTK3", "ENSBTAT00000075020" ] }, "reaction_10063010": { "compartment": "compartment_20699", "id": "reaction_10063010", "reactome": "R-BTA-2022887", "name": "NDST1-4 N-deacetylates GlcNAc residues in heparan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_10063007" ], "products": [ "species_10062948", "species_2022890" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063586": { "compartment": "compartment_17963", "id": "reaction_10063586", "reactome": "R-BTA-2076383", "name": "HS3ST1 sulfates GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063583", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VCB5", "ENSBTAT00000009799" ] }, "reaction_10051589": { "compartment": "compartment_20699", "id": "reaction_10051589", "reactome": "R-BTA-744231", "name": "SLC35D2 exchanges UDP-sugars for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744229", "species_735698" ], "products": [ "species_109402", "species_744234" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "species_29410", "species_914003", "species_29410", "species_914003", "ENSBTAT00000026562" ] }, "reaction_10084090": { "compartment": "compartment_70101", "id": "reaction_10084090", "reactome": "R-BTA-8853429", "name": "PHLDA1 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084084" ], "products": [ "species_10084088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084096": { "compartment": "compartment_70101", "id": "reaction_10084096", "reactome": "R-BTA-8853444", "name": "AURKA phosphorylates PHLDA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084088" ], "products": [ "species_10084086", "species_29370", "species_10084093" ], "modifiers": [ [ "species_10084088", "catalyst" ] ], "additional_components": [ "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590", "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10076112": { "compartment": "compartment_7660", "id": "reaction_10076112", "reactome": "R-BTA-5691381", "name": "MYSM1 deubiquitinates Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076107" ], "products": [ "species_10036828", "species_10076109" ], "modifiers": [ [ "species_10076107", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652" ] }, "reaction_10076119": { "compartment": "compartment_70101", "id": "reaction_10076119", "reactome": "R-BTA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539" ], "products": [ "species_10039537" ], "modifiers": [ [ "species_10076116", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "ENSBTAT00000046166" ] }, "reaction_10089947": { "compartment": "compartment_876", "id": "reaction_10089947", "reactome": "R-BTA-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089943", "species_10073483" ], "products": [ "species_10089945" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495" ] }, "reaction_10092364": { "compartment": "compartment_876", "id": "reaction_10092364", "reactome": "R-BTA-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073483" ], "products": [ "species_10092362" ], "modifiers": [], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438" ] }, "reaction_10089937": { "compartment": "compartment_70101", "id": "reaction_10089937", "reactome": "R-BTA-9013109", "name": "RHOC GEFs activate RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089932" ], "products": [ "species_29420", "species_10073483" ], "modifiers": [ [ "species_10089934", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LFQ5", "ENSBTAT00000066417", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LQ45", "ENSBTAT00000078928", "F1N2G5", "ENSBTAT00000002373", "F1MB21", "ENSBTAT00000017829" ] }, "reaction_10089952": { "compartment": "compartment_876", "id": "reaction_10089952", "reactome": "R-BTA-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073483" ], "products": [ "species_29372", "species_10089932" ], "modifiers": [ [ "species_10089949", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "E1BM23", "ENSBTAT00000038690", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092392": { "compartment": "compartment_12045", "id": "reaction_10092392", "reactome": "R-BTA-9714691", "name": "RAC3 binds ER effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092388", "species_10092384" ], "products": [ "species_10092390" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090330": { "compartment": "compartment_876", "id": "reaction_10090330", "reactome": "R-BTA-9018804", "name": "RAC3 GEFs activate RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090323" ], "products": [ "species_10090325", "species_29420" ], "modifiers": [ [ "species_10090327", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "A5PK69", "ENSBTAT00000079280", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10092394": { "compartment": "compartment_876", "id": "reaction_10092394", "reactome": "R-BTA-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090325" ], "products": [ "species_10092388" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090349": { "compartment": "compartment_876", "id": "reaction_10090349", "reactome": "R-BTA-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090341", "species_10090323" ], "products": [ "species_10090347" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "species_29420", "A5PK69", "ENSBTAT00000079280" ] }, "reaction_10090339": { "compartment": "compartment_876", "id": "reaction_10090339", "reactome": "R-BTA-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090325" ], "products": [ "species_29372", "species_10090323" ], "modifiers": [ [ "species_10090336", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29420", "F1N6V1", "ENSBTAT00000003400", "A4IF90", "ENSBTAT00000061453", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089930": { "compartment": "compartment_876", "id": "reaction_10089930", "reactome": "R-BTA-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089926", "species_10037315" ], "products": [ "species_10089928" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371" ] }, "reaction_10089149": { "compartment": "compartment_70101", "id": "reaction_10089149", "reactome": "R-BTA-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037315" ], "products": [ "species_29372", "species_10037313" ], "modifiers": [ [ "species_10089146", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29420", "Q08DB1", "ENSBTAT00000039899", "F1MGB9", "ENSBTAT00000052139", "A0A3Q1M2Q1", "ENSBTAT00000076617", "E1BI70", "ENSBTAT00000027682", "F1MYQ4", "ENSBTAT00000011665", "G3MXE8", "ENSBTAT00000066138", "E1BIM3", "ENSBTAT00000035838", "E1BM23", "ENSBTAT00000038690", "F1MWY5", "ENSBTAT00000023764", "F1N6V1", "ENSBTAT00000003400", "A4FV18", "ENSBTAT00000020147", "A0A3Q1LWV5", "ENSBTAT00000075058", "A0A3Q1LGT5", "ENSBTAT00000075956" ] }, "reaction_10089888": { "compartment": "compartment_12045", "id": "reaction_10089888", "reactome": "R-BTA-9013004", "name": "RHOA binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089862", "species_10089884" ], "products": [ "species_10089886" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089011": { "compartment": "compartment_70101", "id": "reaction_10089011", "reactome": "R-BTA-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10089008", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1MRV3", "ENSBTAT00000083879", "E1BH51", "ENSBTAT00000005514", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1M8D9", "ENSBTAT00000071999", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LNE2", "ENSBTAT00000077218", "E1BDY4", "ENSBTAT00000082024", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LFQ5", "ENSBTAT00000066417", "Q08DA6", "ENSBTAT00000011773", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1MA88", "ENSBTAT00000069507", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10089890": { "compartment": "compartment_876", "id": "reaction_10089890", "reactome": "R-BTA-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315" ], "products": [ "species_10089862" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089860": { "compartment": "compartment_70101", "id": "reaction_10089860", "reactome": "R-BTA-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313", "species_10089854" ], "products": [ "species_10089858" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "ENSBTAT00000007933", "A0A452DIS6", "ENSBTAT00000007933", "P61585", "ENSBTAT00000005600", "species_29420" ] }, "reaction_10090125": { "compartment": "compartment_70101", "id": "reaction_10090125", "reactome": "R-BTA-9014456", "name": "GDIs block activation of RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089854", "species_10090093" ], "products": [ "species_10090123" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007933", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29420", "A0A452DIS6", "ENSBTAT00000007933" ] }, "reaction_10090145": { "compartment": "compartment_12045", "id": "reaction_10090145", "reactome": "R-BTA-9014467", "name": "RHOG binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090117", "species_10090141" ], "products": [ "species_10090143" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090115": { "compartment": "compartment_876", "id": "reaction_10090115", "reactome": "R-BTA-9014449", "name": "RHOG binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090111", "species_10037305" ], "products": [ "species_10090113" ], "modifiers": [], "additional_components": [ "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570" ] }, "reaction_10090098": { "compartment": "compartment_876", "id": "reaction_10090098", "reactome": "R-BTA-9014433", "name": "RHOG GEFs activate RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090093" ], "products": [ "species_29420", "species_10037305" ], "modifiers": [ [ "species_10090095", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090103": { "compartment": "compartment_876", "id": "reaction_10090103", "reactome": "R-BTA-9014434", "name": "RHOG GAPs stimulate RHOG GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037305" ], "products": [ "species_29372", "species_10090093" ], "modifiers": [ [ "species_10090100", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10090119": { "compartment": "compartment_876", "id": "reaction_10090119", "reactome": "R-BTA-9014454", "name": "RHOG translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037305" ], "products": [ "species_10090117" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090089": { "compartment": "compartment_876", "id": "reaction_10090089", "reactome": "R-BTA-9014420", "name": "RAC2 translocates to the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10073712" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090091": { "compartment": "compartment_1222693", "id": "reaction_10090091", "reactome": "R-BTA-9014424", "name": "RAC2 binds effectors at the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090077": { "compartment": "compartment_70101", "id": "reaction_10090077", "reactome": "R-BTA-9014294", "name": "RAC2 binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299", "species_10090073" ], "products": [ "species_10090075" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092380": { "compartment": "compartment_12045", "id": "reaction_10092380", "reactome": "R-BTA-9714481", "name": "RAC2 binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092374", "species_10092376" ], "products": [ "species_10092378" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092382": { "compartment": "compartment_876", "id": "reaction_10092382", "reactome": "R-BTA-9714483", "name": "RAC2 translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092374" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090082": { "compartment": "compartment_70101", "id": "reaction_10090082", "reactome": "R-BTA-9014295", "name": "RAC2 GAPs stimulate RAC2 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037299" ], "products": [ "species_29372", "species_10090033" ], "modifiers": [ [ "species_10090079", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092370": { "compartment": "compartment_876", "id": "reaction_10092370", "reactome": "R-BTA-9714480", "name": "RAC2 translocates to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092368" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090087": { "compartment": "compartment_70101", "id": "reaction_10090087", "reactome": "R-BTA-9014296", "name": "RAC2 GEFs activate RAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090033" ], "products": [ "species_29420", "species_10037299" ], "modifiers": [ [ "species_10090084", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29420", "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1M4M7", "ENSBTAT00000071096", "A0A3Q1MKN5", "ENSBTAT00000080659", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090203": { "compartment": "compartment_876", "id": "reaction_10090203", "reactome": "R-BTA-9017491", "name": "RHOJ GEFs activate RHOJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090193" ], "products": [ "species_29420", "species_10090191" ], "modifiers": [ [ "species_10090200", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29420", "A4FV20", "ENSBTAT00000022858", "species_29438", "E1BNA6", "ENSBTAT00000002840" ] }, "reaction_10090198": { "compartment": "compartment_876", "id": "reaction_10090198", "reactome": "R-BTA-9017488", "name": "RHOJ GAPs stimulate RHOJ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090191" ], "products": [ "species_29372", "species_10090193" ], "modifiers": [ [ "species_10090195", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29438", "A4FV20", "ENSBTAT00000022858", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10091994": { "compartment": "compartment_70101", "id": "reaction_10091994", "reactome": "R-BTA-9696266", "name": "RND2 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091990", "species_10091948" ], "products": [ "species_10091992" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393", "F1MUP6", "ENSBTAT00000009719", "species_29438", "F1MUP6", "ENSBTAT00000009719", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393" ] }, "reaction_10092022": { "compartment": "compartment_70101", "id": "reaction_10092022", "reactome": "R-BTA-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091946" ], "products": [ "species_10091948" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009719", "F1MUP6", "ENSBTAT00000009719", "species_29438" ] }, "reaction_10091832": { "compartment": "compartment_876", "id": "reaction_10091832", "reactome": "R-BTA-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091827" ], "products": [ "species_29420", "species_10091829" ], "modifiers": [ [ "species_10091827", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29420", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420" ] }, "reaction_10091864": { "compartment": "compartment_876", "id": "reaction_10091864", "reactome": "R-BTA-9693125", "name": "RHOF binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091860", "species_10091829" ], "products": [ "species_10091862" ], "modifiers": [], "additional_components": [ "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393" ] }, "reaction_10091921": { "compartment": "compartment_876", "id": "reaction_10091921", "reactome": "R-BTA-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10091829" ], "products": [ "species_29372", "species_10091827" ], "modifiers": [ [ "species_10091918", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420", "F6RWK1", "ENSBTAT00000043933" ] }, "reaction_10090266": { "compartment": "compartment_70101", "id": "reaction_10090266", "reactome": "R-BTA-9018746", "name": "RHOQ binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090262", "species_10090239" ], "products": [ "species_10090264" ], "modifiers": [], "additional_components": [ "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391", "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438", "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391" ] }, "reaction_10090369": { "compartment": "compartment_876", "id": "reaction_10090369", "reactome": "R-BTA-9018836", "name": "RHOQ translocates to the Golgi-associated vesicle membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090239" ], "products": [ "species_10090367" ], "modifiers": [], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438" ] }, "reaction_10090246": { "compartment": "compartment_70101", "id": "reaction_10090246", "reactome": "R-BTA-9018745", "name": "RHOQ GAPs stimulate RHOQ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090239" ], "products": [ "species_29372", "species_10090241" ], "modifiers": [ [ "species_10090243", "catalyst" ] ], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29420", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092002": { "compartment": "compartment_70101", "id": "reaction_10092002", "reactome": "R-BTA-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091998" ], "products": [ "species_10092000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045869", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10092020": { "compartment": "compartment_70101", "id": "reaction_10092020", "reactome": "R-BTA-9696268", "name": "RND3 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092016", "species_10092000" ], "products": [ "species_10092018" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10063353": { "compartment": "compartment_70101", "id": "reaction_10063353", "reactome": "R-BTA-2029460", "name": "PAK1 phosphorylates LIMK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047644", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "ENSBTAT00000080749" ] }, "reaction_10073755": { "compartment": "compartment_70101", "id": "reaction_10073755", "reactome": "R-BTA-5668731", "name": "NOX3 complex:RAC1:GTP generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_352327" ], "products": [ "species_70106", "species_29366", "species_3299686" ], "modifiers": [ [ "species_10073752", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "E1BFF3", "ENSBTAT00000018021", "species_29438" ] }, "reaction_10091180": { "compartment": "compartment_70101", "id": "reaction_10091180", "reactome": "R-BTA-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091177" ], "products": [ "species_29370", "species_10091162" ], "modifiers": [ [ "species_10040565", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10091169": { "compartment": "compartment_70101", "id": "reaction_10091169", "reactome": "R-BTA-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091164", "species_10091162" ], "products": [ "species_10091166" ], "modifiers": [ [ "species_10091164", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022592", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "ENSBTAT00000022592" ] }, "reaction_10073731": { "compartment": "compartment_263698", "id": "reaction_10073731", "reactome": "R-BTA-5668629", "name": "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_29364" ], "products": [ "species_70106", "species_2000345", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ], [ "species_10073729", "catalyst" ], [ "species_1629751", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438", "species_74016", "P28782", "ENSBTAT00000066555", "species_140356", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10073716": { "compartment": "compartment_1222693", "id": "reaction_10073716", "reactome": "R-BTA-5668605", "name": "RAC2:GTP binds NOX2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10091175": { "compartment": "compartment_70101", "id": "reaction_10091175", "reactome": "R-BTA-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091166" ], "products": [ "species_10091173", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10063374": { "compartment": "compartment_70101", "id": "reaction_10063374", "reactome": "R-BTA-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043441", "species_10063372" ], "products": [ "species_10061166" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_29370", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "P63258", "ENSBTAT00000008132" ] }, "reaction_10073577": { "compartment": "compartment_70101", "id": "reaction_10073577", "reactome": "R-BTA-5667008", "name": "RHOA:GTP binds RHPN1 or RHPN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073573", "species_10037315" ], "products": [ "species_10073575" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073587", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LJH7", "ENSBTAT00000073587" ] }, "reaction_10072515": { "compartment": "compartment_70101", "id": "reaction_10072515", "reactome": "R-BTA-5625959", "name": "Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072511", "species_10072505" ], "products": [ "species_10072513" ], "modifiers": [], "additional_components": [ "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073842": { "compartment": "compartment_70101", "id": "reaction_10073842", "reactome": "R-BTA-5672083", "name": "KTN1 binds Kinesin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072513", "species_10055513" ], "products": [ "species_10073840" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073806": { "compartment": "compartment_876", "id": "reaction_10073806", "reactome": "R-BTA-5671993", "name": "CIT-3 binds DLG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073802", "species_10050472" ], "products": [ "species_10073804" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "ENSBTAT00000003326", "F1MM66", "ENSBTAT00000003326", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600" ] }, "reaction_10073796": { "compartment": "compartment_70101", "id": "reaction_10073796", "reactome": "R-BTA-5671970", "name": "Activated CIT binds KIF14 and PRC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073792", "species_10073788", "species_10073784" ], "products": [ "species_10073794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076885", "ENSBTAT00000029161", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "G5E5S3", "ENSBTAT00000029161", "Q2T9P1", "ENSBTAT00000076885" ] }, "reaction_10073561": { "compartment": "compartment_70101", "id": "reaction_10073561", "reactome": "R-BTA-5666001", "name": "Profilin:G-actin binds MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541", "species_10043459" ], "products": [ "species_10073543" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073503": { "compartment": "compartment_70101", "id": "reaction_10073503", "reactome": "R-BTA-5665761", "name": "FMNL3 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073499", "species_10073483" ], "products": [ "species_10073501" ], "modifiers": [], "additional_components": [ "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075" ] }, "reaction_10073525": { "compartment": "compartment_876", "id": "reaction_10073525", "reactome": "R-BTA-5665802", "name": "SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073521", "species_10073517" ], "products": [ "species_10073523" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068363", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LMM5", "ENSBTAT00000068363" ] }, "reaction_10073493": { "compartment": "compartment_876", "id": "reaction_10073493", "reactome": "R-BTA-5665748", "name": "FMNL2 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073489", "species_10073483" ], "products": [ "species_10073491" ], "modifiers": [], "additional_components": [ "A0A3Q1LSX9", "ENSBTAT00000073284", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LSX9", "ENSBTAT00000073284" ] }, "reaction_10073557": { "compartment": "compartment_7660", "id": "reaction_10073557", "reactome": "R-BTA-5665998", "name": "MKL1 binds SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068967", "species_10073553" ], "products": [ "species_10073555" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000016981", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073559": { "compartment": "compartment_70101", "id": "reaction_10073559", "reactome": "R-BTA-5665999", "name": "MKL1 translocates from cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541" ], "products": [ "species_10068967" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000070929" ] }, "reaction_10073547": { "compartment": "compartment_70101", "id": "reaction_10073547", "reactome": "R-BTA-5665982", "name": "RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073543", "species_10073539", "species_10073537" ], "products": [ "species_10073541", "species_10073545" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929", "A0A3Q1MSR1", "ENSBTAT00000069763", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000070929", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1MSR1", "ENSBTAT00000069763", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068939": { "compartment": "compartment_70101", "id": "reaction_10068939", "reactome": "R-BTA-3858495", "name": "DAAM1 recruits GTP-bound RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068935", "species_10068931" ], "products": [ "species_10068937" ], "modifiers": [], "additional_components": [ "species_29926", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "species_29926", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073549": { "compartment": "compartment_70101", "id": "reaction_10073549", "reactome": "R-BTA-5665989", "name": "DIAPH1 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315", "species_10073535" ], "products": [ "species_10073537" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073569": { "compartment": "compartment_7660", "id": "reaction_10073569", "reactome": "R-BTA-5666008", "name": "SCAI binds SRF:MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073555", "species_10073565" ], "products": [ "species_10073567" ], "modifiers": [], "additional_components": [ "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929", "ENSBTAT00000072829", "A0A3Q1M5I0", "ENSBTAT00000072829", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073507": { "compartment": "compartment_70101", "id": "reaction_10073507", "reactome": "R-BTA-5665767", "name": "Activated FMNL3 binds G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043459", "species_10073501" ], "products": [ "species_10073505" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10043461": { "compartment": "compartment_70101", "id": "reaction_10043461", "reactome": "R-BTA-203070", "name": "Association of profilin with monomeric actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043457", "species_10043441" ], "products": [ "species_10043459" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068933": { "compartment": "compartment_70101", "id": "reaction_10068933", "reactome": "R-BTA-3858489", "name": "ppDVL binds DAAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068929", "species_10068927" ], "products": [ "species_10068931" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000075877", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10092203": { "compartment": "compartment_263163", "id": "reaction_10092203", "reactome": "R-BTA-9706390", "name": "RHOBTB3 binds interacting proteins at trans-Golgi network", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092199", "species_10083329" ], "products": [ "species_10092201" ], "modifiers": [], "additional_components": [ "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10092205": { "compartment": "compartment_263163", "id": "reaction_10092205", "reactome": "R-BTA-9706393", "name": "RHOBTB3 binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083327" ], "products": [ "species_10083329" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080085", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10092208": { "compartment": "compartment_263163", "id": "reaction_10092208", "reactome": "R-BTA-9706399", "name": "RHOBTB3 hydrolyzes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083329" ], "products": [ "species_10083335", "species_29372" ], "modifiers": [ [ "species_10083329", "catalyst" ] ], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10071262": { "compartment": "compartment_13231", "id": "reaction_10071262", "reactome": "R-BTA-5252001", "name": "ATP1B4 binds SNW1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044442", "species_10071258" ], "products": [ "species_10071260" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010697", "ENSBTAT00000011740", "A7MB71", "ENSBTAT00000011740", "Q1JQE0", "ENSBTAT00000010697" ] }, "reaction_10064933": { "compartment": "compartment_7660", "id": "reaction_10064933", "reactome": "R-BTA-2186767", "name": "Degradation of ubiquitinated SKI/SKIL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064931" ], "products": [], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N727", "ENSBTAT00000060953", "E1BJ37", "ENSBTAT00000005438" ] }, "reaction_10043311": { "compartment": "compartment_876", "id": "reaction_10043311", "reactome": "R-BTA-202604", "name": "Formation of a heteromeric BMP receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042988", "species_10043000" ], "products": [ "species_10043002" ], "modifiers": [], "additional_components": [ "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282" ] }, "reaction_10084542": { "compartment": "compartment_984", "id": "reaction_10084542", "reactome": "R-BTA-8858346", "name": "AMHR2 binds AMH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084532", "species_10084538" ], "products": [ "species_10084540" ], "modifiers": [], "additional_components": [ "F1MZL1", "ENSBTAT00000019912", "E1BHR7", "ENSBTAT00000024657", "E1BHR7", "ENSBTAT00000024657", "F1MZL1", "ENSBTAT00000019912" ] }, "reaction_10042976": { "compartment": "compartment_70101", "id": "reaction_10042976", "reactome": "R-BTA-201445", "name": "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042969" ], "products": [], "modifiers": [ [ "species_10042973", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072746", "ENSBTAT00000043725" ] }, "reaction_10056354": { "compartment": "compartment_876", "id": "reaction_10056354", "reactome": "R-BTA-1181149", "name": "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056341", "species_113592" ], "products": [ "species_29370", "species_10056351" ], "modifiers": [ [ "species_10056341", "catalyst" ] ], "additional_components": [ "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665", "F1MSQ2", "ENSBTAT00000046665", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10056356": { "compartment": "compartment_876", "id": "reaction_10056356", "reactome": "R-BTA-1181153", "name": "Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056339", "species_10042992", "species_10045724" ], "products": [ "species_10056341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046665", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10068704": { "compartment": "compartment_70101", "id": "reaction_10068704", "reactome": "R-BTA-3772434", "name": "Phosphorylated DVL recruits PIP5K1B to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060420", "species_10043116" ], "products": [ "species_10068702" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080996", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10068707": { "compartment": "compartment_70101", "id": "reaction_10068707", "reactome": "R-BTA-3772436", "name": "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10068702", "catalyst" ] ], "additional_components": [ "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10067694": { "compartment": "compartment_7660", "id": "reaction_10067694", "reactome": "R-BTA-3322429", "name": "XIAP monoubiquinates TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10067672" ], "products": [ "species_10067691" ], "modifiers": [ [ "species_10067672", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067696": { "compartment": "compartment_7660", "id": "reaction_10067696", "reactome": "R-BTA-3322431", "name": "XIAP binds TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067670", "species_10067668" ], "products": [ "species_10067672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067698": { "compartment": "compartment_7660", "id": "reaction_10067698", "reactome": "R-BTA-3322434", "name": "XIAP dissociates from ub-TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067691" ], "products": [ "species_10067670", "species_10067689" ], "modifiers": [], "additional_components": [ "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289" ] }, "reaction_10068095": { "compartment": "compartment_70101", "id": "reaction_10068095", "reactome": "R-BTA-3640872", "name": "USP34 deubiquitinates AXIN1,AXIN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068083" ], "products": [ "species_10068071", "species_10033408" ], "modifiers": [ [ "species_10068092", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000078346" ] }, "reaction_10068073": { "compartment": "compartment_70101", "id": "reaction_10068073", "reactome": "R-BTA-3640844", "name": "RNF146 binds RibC-AXIN:TNKS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068054", "species_10068069" ], "products": [ "species_10068071" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10068088": { "compartment": "compartment_70101", "id": "reaction_10068088", "reactome": "R-BTA-3640862", "name": "Tankyrase binds AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041524", "species_10068067" ], "products": [ "species_10068075" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068078": { "compartment": "compartment_70101", "id": "reaction_10068078", "reactome": "R-BTA-3640858", "name": "Tankyrase ADP-ribosylates AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068075", "species_29360" ], "products": [ "species_197277", "species_10068069" ], "modifiers": [ [ "species_10068075", "catalyst" ] ], "additional_components": [ "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068086": { "compartment": "compartment_70101", "id": "reaction_10068086", "reactome": "R-BTA-3640861", "name": "RNF146 ubiquitinates ADP-ribosylated AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068071", "species_10033408" ], "products": [ "species_10068083" ], "modifiers": [ [ "species_10068071", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10067879": { "compartment": "compartment_7660", "id": "reaction_10067879", "reactome": "R-BTA-3364026", "name": "SET1 complex trimethylates H3K4 at the MYC gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10067848" ], "products": [ "species_77502", "species_10067852" ], "modifiers": [ [ "species_10067876", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "F1MHP8", "ENSBTAT00000012057", "E1BEP4", "ENSBTAT00000001294", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A4FUE3", "ENSBTAT00000021204", "E1BPF3", "ENSBTAT00000080372", "A0A3Q1M6V2", "ENSBTAT00000067448", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10071330": { "compartment": "compartment_984", "id": "reaction_10071330", "reactome": "R-BTA-5323545", "name": "Canonical WNT signaling through the atypical receptor RYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071326", "species_10071324" ], "products": [ "species_10071328" ], "modifiers": [], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000071795", "A0A3Q1N0Q2", "ENSBTAT00000071795", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10069645": { "compartment": "compartment_876", "id": "reaction_10069645", "reactome": "R-BTA-4641205", "name": "RSPO:LGR binds ZNRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069631", "species_10069641" ], "products": [ "species_10069643" ], "modifiers": [], "additional_components": [ "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069647": { "compartment": "compartment_876", "id": "reaction_10069647", "reactome": "R-BTA-4641206", "name": "RSPOs bind LGRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069615", "species_10069629" ], "products": [ "species_10069631" ], "modifiers": [], "additional_components": [ "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069664": { "compartment": "compartment_876", "id": "reaction_10069664", "reactome": "R-BTA-4641246", "name": "ZNRF3 autoubiquitinates to promote its internalization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069643" ], "products": [ "species_10069661" ], "modifiers": [ [ "species_10069643", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069607": { "compartment": "compartment_70101", "id": "reaction_10069607", "reactome": "R-BTA-4641147", "name": "DACT1 binds DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069603", "species_10043149" ], "products": [ "species_10069605" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025871", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MP88", "ENSBTAT00000025871" ] }, "reaction_10068923": { "compartment": "compartment_876", "id": "reaction_10068923", "reactome": "R-BTA-3858482", "name": "DVL is recruited to the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068919", "species_10068917" ], "products": [ "species_10068921" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069896": { "compartment": "compartment_876", "id": "reaction_10069896", "reactome": "R-BTA-5140741", "name": "WNT5A binds FZD and ROR receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069892", "species_10067196" ], "products": [ "species_10069894" ], "modifiers": [], "additional_components": [ "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10069882": { "compartment": "compartment_876", "id": "reaction_10069882", "reactome": "R-BTA-5138441", "name": "WNT5A-FZD4 recruits DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069874", "species_10043149" ], "products": [ "species_10069878" ], "modifiers": [], "additional_components": [ "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069876": { "compartment": "compartment_876", "id": "reaction_10069876", "reactome": "R-BTA-5099899", "name": "WNT5A binds FZD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069862", "species_10067196" ], "products": [ "species_10069874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061370", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069299": { "compartment": "compartment_70101", "id": "reaction_10069299", "reactome": "R-BTA-3965450", "name": "DAAM1 recruits PFN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068931", "species_10043451" ], "products": [ "species_10069297" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069448": { "compartment": "compartment_70101", "id": "reaction_10069448", "reactome": "R-BTA-4332358", "name": "Dissociation of CaM and CAMK2 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069445", "species_113592" ], "products": [ "species_29370", "species_10069441", "species_10037002" ], "modifiers": [ [ "species_10069445", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069456": { "compartment": "compartment_70101", "id": "reaction_10069456", "reactome": "R-BTA-4332359", "name": "Active calmodulin binds CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069452", "species_10037002" ], "products": [ "species_10069454" ], "modifiers": [], "additional_components": [ "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069459": { "compartment": "compartment_70101", "id": "reaction_10069459", "reactome": "R-BTA-4332363", "name": "Autophosphorylation and activation of CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069454" ], "products": [ "species_10069445", "species_29370" ], "modifiers": [ [ "species_10069454", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10067128": { "compartment": "compartment_20699", "id": "reaction_10067128", "reactome": "R-BTA-3247840", "name": "WLS binds WNT ligands in the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067122", "species_10066990" ], "products": [ "species_10067126" ], "modifiers": [], "additional_components": [ "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067200": { "compartment": "compartment_984", "id": "reaction_10067200", "reactome": "R-BTA-3247843", "name": "secretion of WNT ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10067198", "species_10067130" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "A0A3Q1M1A0", "ENSBTAT00000086580", "A6H6X8", "ENSBTAT00000018985", "E1BDG5", "ENSBTAT00000026930", "E1BKL2", "ENSBTAT00000035270", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "F1MHG3", "ENSBTAT00000017163", "A0A3Q1MPF5", "ENSBTAT00000081055", "A4D7S0", "ENSBTAT00000010650", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MEW8", "ENSBTAT00000012148", "F1MK64", "ENSBTAT00000020402", "F1N4C0", "ENSBTAT00000014355", "ENSBTAT00000077814" ] }, "reaction_10067202": { "compartment": "compartment_20699", "id": "reaction_10067202", "reactome": "R-BTA-3247844", "name": "WNT ligands traffic to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067126" ], "products": [ "species_10067168" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592" ] }, "reaction_10066994": { "compartment": "compartment_20699", "id": "reaction_10066994", "reactome": "R-BTA-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066988" ], "products": [ "species_10066992" ], "modifiers": [], "additional_components": [ "Q1RMH8", "ENSBTAT00000025026", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q1RMH8", "ENSBTAT00000025026", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239" ] }, "reaction_10068837": { "compartment": "compartment_383505", "id": "reaction_10068837", "reactome": "R-BTA-3781941", "name": "WNTs are secreted in exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068795" ], "products": [ "species_10068835" ], "modifiers": [], "additional_components": [ "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978" ] }, "reaction_10067124": { "compartment": "compartment_17963", "id": "reaction_10067124", "reactome": "R-BTA-3247837", "name": "WNT ligands traffic to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067086" ], "products": [ "species_10067122" ], "modifiers": [], "additional_components": [ "F1N6L8", "ENSBTAT00000002188", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1LVG1", "ENSBTAT00000068978", "A0A3Q1MQ82", "ENSBTAT00000083229", "A0A3Q1MJR6", "ENSBTAT00000085976", "F1MN70", "ENSBTAT00000018592", "E1BEN9", "ENSBTAT00000020414", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067204": { "compartment": "compartment_171062", "id": "reaction_10067204", "reactome": "R-BTA-3247847", "name": "WLS is endocytosed to the early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067130" ], "products": [ "species_10066982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077814", "ENSBTAT00000077814" ] }, "reaction_10068839": { "compartment": "compartment_876", "id": "reaction_10068839", "reactome": "R-BTA-3781943", "name": "WLS:WNT complex is internalized for maturation into exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10068795" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814" ] }, "reaction_10041640": { "compartment": "compartment_70101", "id": "reaction_10041640", "reactome": "R-BTA-195300", "name": "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041614" ], "products": [ "species_29370", "species_10041594" ], "modifiers": [ [ "species_10041614", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041629": { "compartment": "compartment_70101", "id": "reaction_10041629", "reactome": "R-BTA-195283", "name": "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041610" ], "products": [ "species_29370", "species_10041614" ], "modifiers": [ [ "species_10041610", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041647": { "compartment": "compartment_70101", "id": "reaction_10041647", "reactome": "R-BTA-195318", "name": "Phosphorylation of beta-catenin at Ser45 by CK1 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041644" ], "products": [ "species_10041634", "species_29370" ], "modifiers": [ [ "species_10041644", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041637": { "compartment": "compartment_70101", "id": "reaction_10041637", "reactome": "R-BTA-195287", "name": "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041634", "species_113592" ], "products": [ "species_29370", "species_10041610" ], "modifiers": [ [ "species_10041634", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063849": { "compartment": "compartment_70101", "id": "reaction_10063849", "reactome": "R-BTA-2130286", "name": "Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10063841" ], "products": [ "species_10063845" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10087597": { "compartment": "compartment_7660", "id": "reaction_10087597", "reactome": "R-BTA-8944349", "name": "TLE tetramers bind TCF/LEF at WNT promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067668", "species_10087593" ], "products": [ "species_10087595" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10071356": { "compartment": "compartment_7660", "id": "reaction_10071356", "reactome": "R-BTA-5334050", "name": "TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071346", "species_10071352" ], "products": [ "species_10071354" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1MAN6", "ENSBTAT00000079320" ] }, "reaction_10069651": { "compartment": "compartment_7660", "id": "reaction_10069651", "reactome": "R-BTA-4641229", "name": "TLE oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069649" ], "products": [ "species_10067668" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10041583": { "compartment": "compartment_70101", "id": "reaction_10041583", "reactome": "R-BTA-195251", "name": "Assembly of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041524", "species_10041570", "species_10041520", "species_10041566", "species_10041579" ], "products": [ "species_10041581" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "ENSBTAT00000087508", "ENSBTAT00000011639", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "ENSBTAT00000086393", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10070931": { "compartment": "compartment_70101", "id": "reaction_10070931", "reactome": "R-BTA-5229343", "name": "AXIN is phosphorylated in the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041581" ], "products": [ "species_10041590", "species_29370" ], "modifiers": [ [ "species_10041581", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063843": { "compartment": "compartment_70101", "id": "reaction_10063843", "reactome": "R-BTA-2130279", "name": "Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10041599" ], "products": [ "species_10063841" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10041604": { "compartment": "compartment_70101", "id": "reaction_10041604", "reactome": "R-BTA-195275", "name": "Phosphorylation of APC component of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041594" ], "products": [ "species_29370", "species_10041599" ], "modifiers": [ [ "species_10041594", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041606": { "compartment": "compartment_70101", "id": "reaction_10041606", "reactome": "R-BTA-195280", "name": "Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041599" ], "products": [ "species_10041599" ], "modifiers": [], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10060556": { "compartment": "compartment_876", "id": "reaction_10060556", "reactome": "R-BTA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060448": { "compartment": "compartment_876", "id": "reaction_10060448", "reactome": "R-BTA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060445", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10087531": { "compartment": "compartment_7660", "id": "reaction_10087531", "reactome": "R-BTA-8943817", "name": "MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087525", "species_10087523" ], "products": [ "species_10087529" ], "modifiers": [], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "A0A3Q1MWB8", "ENSBTAT00000079180" ] }, "reaction_10065099": { "compartment": "compartment_70101", "id": "reaction_10065099", "reactome": "R-BTA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043178", "species_179856" ], "products": [ "species_10065097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "species_6810412", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10065227": { "compartment": "compartment_70101", "id": "reaction_10065227", "reactome": "R-BTA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10043178" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036981": { "compartment": "compartment_7660", "id": "reaction_10036981", "reactome": "R-BTA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10036972" ], "products": [ "species_113582", "species_10036978" ], "modifiers": [ [ "species_10036972", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155" ] }, "reaction_10049478": { "compartment": "compartment_70101", "id": "reaction_10049478", "reactome": "R-BTA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10049470" ], "products": [ "species_113582", "species_10049475" ], "modifiers": [ [ "species_10049470", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10037022": { "compartment": "compartment_70101", "id": "reaction_10037022", "reactome": "R-BTA-111955", "name": "cAMP hydrolysis by Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037019", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318" ] }, "reaction_10037024": { "compartment": "compartment_70101", "id": "reaction_10037024", "reactome": "R-BTA-111956", "name": "Calmodulin activates Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037019" ], "products": [ "species_10037019" ], "modifiers": [ [ "species_10037002", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10037004": { "compartment": "compartment_876", "id": "reaction_10037004", "reactome": "R-BTA-111930", "name": "Adenylate cyclase produces cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10036997", "catalyst" ], [ "species_10037002", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10041863": { "compartment": "compartment_876", "id": "reaction_10041863", "reactome": "R-BTA-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041855" ], "products": [ "species_10041860", "species_29370" ], "modifiers": [ [ "species_10041855", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078659", "ENSBTAT00000078659", "ENSBTAT00000078659" ] }, "reaction_10063544": { "compartment": "compartment_70101", "id": "reaction_10063544", "reactome": "R-BTA-2064406", "name": "Translocation of YAP1:ZO-2 (TJP2) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063538" ], "products": [ "species_10063542" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10063550": { "compartment": "compartment_70101", "id": "reaction_10063550", "reactome": "R-BTA-2064417", "name": "WWTR1 (TAZ) binds ZO-1 (TJP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063546" ], "products": [ "species_10063548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000038824", "F1N2D3", "ENSBTAT00000038824", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063408": { "compartment": "compartment_70101", "id": "reaction_10063408", "reactome": "R-BTA-2038398", "name": "KIBRA (WWC1) binds LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063404", "species_10063259" ], "products": [ "species_10063406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019472", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "F1N3I6", "ENSBTAT00000019472" ] }, "reaction_10063568": { "compartment": "compartment_70101", "id": "reaction_10063568", "reactome": "R-BTA-2066299", "name": "DVL2 binds phosphorylated WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043149", "species_10063336" ], "products": [ "species_10063566" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078307", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10063346": { "compartment": "compartment_70101", "id": "reaction_10063346", "reactome": "R-BTA-2028735", "name": "AMOT proteins bind WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10063333" ], "products": [ "species_10063344" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063317": { "compartment": "compartment_70101", "id": "reaction_10063317", "reactome": "R-BTA-2028598", "name": "Phosphorylation of YAP by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063312" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063380": { "compartment": "compartment_70101", "id": "reaction_10063380", "reactome": "R-BTA-2032768", "name": "Translocation of WWTR1 (TAZ) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333" ], "products": [ "species_10063378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991" ] }, "reaction_10063319": { "compartment": "compartment_70101", "id": "reaction_10063319", "reactome": "R-BTA-2028626", "name": "Phosphorylated MOB1A proteins associate with LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063259", "species_10063273" ], "products": [ "species_10063275" ], "modifiers": [], "additional_components": [ "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063382": { "compartment": "compartment_70101", "id": "reaction_10063382", "reactome": "R-BTA-2032770", "name": "Translocation of YAP1 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276" ], "products": [ "species_10057280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112" ] }, "reaction_10063305": { "compartment": "compartment_70101", "id": "reaction_10063305", "reactome": "R-BTA-2028583", "name": "Phosphorylation of YAP by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063290" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063338": { "compartment": "compartment_70101", "id": "reaction_10063338", "reactome": "R-BTA-2028661", "name": "Phosphorylation of WWTR1 (TAZ) by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063342": { "compartment": "compartment_70101", "id": "reaction_10063342", "reactome": "R-BTA-2028724", "name": "AMOT proteins bind YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10057276" ], "products": [ "species_10063340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063534": { "compartment": "compartment_70101", "id": "reaction_10063534", "reactome": "R-BTA-2060328", "name": "Phosphorylation of WWTR1 (TAZ) by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063329": { "compartment": "compartment_70101", "id": "reaction_10063329", "reactome": "R-BTA-2028644", "name": "YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10063290" ], "products": [ "species_10063327" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10063554": { "compartment": "compartment_70101", "id": "reaction_10063554", "reactome": "R-BTA-2064418", "name": "WWTR1 (TAZ) binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063536" ], "products": [ "species_10063552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000069935", "A0A3Q1MEH9", "ENSBTAT00000069935", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063556": { "compartment": "compartment_70101", "id": "reaction_10063556", "reactome": "R-BTA-2064421", "name": "YAP1 binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063536", "species_10057276" ], "products": [ "species_10063538" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069935", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10043753": { "compartment": "compartment_70101", "id": "reaction_10043753", "reactome": "R-BTA-205075", "name": "JNK phosphorylates BIM, BAD and other targets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037714", "species_113592", "species_10037676" ], "products": [ "species_10043750", "species_29370", "species_10043747" ], "modifiers": [ [ "species_10039514", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000087439" ] }, "reaction_10041333": { "compartment": "compartment_13231", "id": "reaction_10041333", "reactome": "R-BTA-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039514" ], "products": [ "species_10039497" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10043739": { "compartment": "compartment_13231", "id": "reaction_10043739", "reactome": "R-BTA-204947", "name": "Polyubiquitinated NRIF migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043729" ], "products": [ "species_10043737" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119" ] }, "reaction_10043744": { "compartment": "compartment_70101", "id": "reaction_10043744", "reactome": "R-BTA-205008", "name": "Polyubiquitinated NRIF binds to p62 (Sequestosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043741", "species_10043723" ], "products": [ "species_10043729" ], "modifiers": [ [ "species_10043723", "catalyst" ] ], "additional_components": [ "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019" ] }, "reaction_10043778": { "compartment": "compartment_70101", "id": "reaction_10043778", "reactome": "R-BTA-205118", "name": "TRAF6 polyubiquitinates NRIF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043719", "species_10043727" ], "products": [ "species_10043741" ], "modifiers": [ [ "species_10043761", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000083119", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10043877": { "compartment": "compartment_70101", "id": "reaction_10043877", "reactome": "R-BTA-209536", "name": "IkB is ubiquitinated and degraded", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043858", "species_10033408" ], "products": [ "species_10043875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022183", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10041470": { "compartment": "compartment_876", "id": "reaction_10041470", "reactome": "R-BTA-194518", "name": "RhoA is activated by nucleotide exchange and inhibits axonal growth", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313" ], "products": [ "species_10037315" ], "modifiers": [ [ "species_10041467", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000083879" ] }, "reaction_10071524": { "compartment": "compartment_876", "id": "reaction_10071524", "reactome": "R-BTA-5357757", "name": "BIRC(cIAP1/2) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10071516" ], "products": [ "species_10071521" ], "modifiers": [ [ "species_10071516", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10071556": { "compartment": "compartment_70101", "id": "reaction_10071556", "reactome": "R-BTA-5357904", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071552", "species_10071521" ], "products": [ "species_10071554" ], "modifiers": [], "additional_components": [ "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670" ] }, "reaction_10071526": { "compartment": "compartment_876", "id": "reaction_10071526", "reactome": "R-BTA-5357780", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036142", "species_10071514" ], "products": [ "species_10071516" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10037964": { "compartment": "compartment_70101", "id": "reaction_10037964", "reactome": "R-BTA-140978", "name": "TRADD:TRAF2:RIP1 complex binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035378", "species_10036144" ], "products": [ "species_10037952" ], "modifiers": [ [ "species_10037962", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10067908": { "compartment": "compartment_984", "id": "reaction_10067908", "reactome": "R-BTA-3371385", "name": "TNF-alpha is cleaved by ADAM17 (TACE)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036154" ], "products": [ "species_10067885", "species_10067899" ], "modifiers": [ [ "species_10067905", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "species_29426", "E1B867", "ENSBTAT00000001519" ] }, "reaction_10092026": { "compartment": "compartment_70101", "id": "reaction_10092026", "reactome": "R-BTA-9697747", "name": "Caspase-8 and FLIP(L) processing at TNFR signaling complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067893" ], "products": [ "species_10092024", "species_10068040" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10092031": { "compartment": "compartment_70101", "id": "reaction_10092031", "reactome": "R-BTA-9697750", "name": "RIPK1 is cleaved by CASP8:FLIP(L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092024" ], "products": [ "species_10092028", "species_10071528" ], "modifiers": [ [ "species_10092024", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10071534": { "compartment": "compartment_70101", "id": "reaction_10071534", "reactome": "R-BTA-5357828", "name": "RIPK1 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952" ], "products": [ "species_10071532", "species_10071528" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "ENSBTAT00000008367", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10084723": { "compartment": "compartment_70101", "id": "reaction_10084723", "reactome": "R-BTA-8863101", "name": "SPPL2a/b cleaves TNF(1-76)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067899" ], "products": [ "species_10084710", "species_10084708" ], "modifiers": [ [ "species_10084720", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "ENSBTAT00000035815", "ENSBTAT00000035815", "A0A3Q1MBP7", "ENSBTAT00000077127", "E1BKF8", "ENSBTAT00000035792" ] }, "reaction_10071541": { "compartment": "compartment_70101", "id": "reaction_10071541", "reactome": "R-BTA-5357845", "name": "RIPK1 is deubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071521" ], "products": [ "species_10033408", "species_10071516" ], "modifiers": [ [ "species_10037962", "catalyst" ], [ "species_10071539", "catalyst" ] ], "additional_components": [ "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1NKI9", "ENSBTAT00000069028", "ENSBTAT00000026221" ] }, "reaction_10067895": { "compartment": "compartment_70101", "id": "reaction_10067895", "reactome": "R-BTA-3371360", "name": "FLIP(L) and procaspase-8 form heterodimer in TNF signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952", "species_10067887", "species_10035384" ], "products": [ "species_10067893" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322" ] }, "reaction_10035726": { "compartment": "compartment_876", "id": "reaction_10035726", "reactome": "R-BTA-75244", "name": "FASL binds FAS Receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033920", "species_10033916" ], "products": [ "species_10033922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014282", "ENSBTAT00000046575", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036146": { "compartment": "compartment_876", "id": "reaction_10036146", "reactome": "R-BTA-83586", "name": "FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035380", "species_10035384" ], "products": [ "species_10035386" ], "modifiers": [], "additional_components": [ "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036148": { "compartment": "compartment_876", "id": "reaction_10036148", "reactome": "R-BTA-83650", "name": "FasL:Fas binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033924", "species_10035378" ], "products": [ "species_10035380" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000024322", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10033926": { "compartment": "compartment_876", "id": "reaction_10033926", "reactome": "R-BTA-71050", "name": "Trimerization of the FASL:FAS receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033922" ], "products": [ "species_10033924" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10045016": { "compartment": "compartment_70101", "id": "reaction_10045016", "reactome": "R-BTA-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10045013", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "species_74016", "species_6797635", "E1BG59", "ENSBTAT00000029159" ] }, "reaction_10053213": { "compartment": "compartment_70101", "id": "reaction_10053213", "reactome": "R-BTA-939265", "name": "Activation of Rap1 by membrane-associated GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10047532", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10049279": { "compartment": "compartment_876", "id": "reaction_10049279", "reactome": "R-BTA-432110", "name": "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037443" ], "products": [ "species_10049276" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "ENSBTAT00000039221" ] }, "reaction_10049506": { "compartment": "compartment_876", "id": "reaction_10049506", "reactome": "R-BTA-443905", "name": "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049502" ], "products": [ "species_10049504" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10071673": { "compartment": "compartment_70101", "id": "reaction_10071673", "reactome": "R-BTA-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071670", "catalyst" ] ], "additional_components": [ "F1MFZ4", "ENSBTAT00000003769", "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10076840": { "compartment": "compartment_70101", "id": "reaction_10076840", "reactome": "R-BTA-5696101", "name": "ALDH8A1 oxidises 9cRAL to 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5362565", "species_29360" ], "products": [ "species_70106", "species_5362520", "species_73473" ], "modifiers": [ [ "species_10076837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010485" ] }, "reaction_10071691": { "compartment": "compartment_70101", "id": "reaction_10071691", "reactome": "R-BTA-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10071688", "catalyst" ] ], "additional_components": [ "F1MZD5", "ENSBTAT00000023493", "E1BM93", "ENSBTAT00000002535", "Q17QW3", "ENSBTAT00000006933" ] }, "reaction_10071659": { "compartment": "compartment_70101", "id": "reaction_10071659", "reactome": "R-BTA-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975622", "species_29360" ], "products": [ "species_70106", "species_5334816", "species_73473" ], "modifiers": [ [ "species_10071656", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661", "F1MHR3", "ENSBTAT00000012030" ] }, "reaction_10072397": { "compartment": "compartment_70101", "id": "reaction_10072397", "reactome": "R-BTA-5622134", "name": "CRABP1 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071664", "species_5334816" ], "products": [ "species_10071666" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017158", "species_215573", "P62964", "ENSBTAT00000017158" ] }, "reaction_10071678": { "compartment": "compartment_70101", "id": "reaction_10071678", "reactome": "R-BTA-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_29360" ], "products": [ "species_70106", "species_32737", "species_73473" ], "modifiers": [ [ "species_10071675", "catalyst" ] ], "additional_components": [ "Q27979", "ENSBTAT00000065932", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10072433": { "compartment": "compartment_70616", "id": "reaction_10072433", "reactome": "R-BTA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10072430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029403" ] }, "reaction_10072225": { "compartment": "compartment_70101", "id": "reaction_10072225", "reactome": "R-BTA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10071648": { "compartment": "compartment_70101", "id": "reaction_10071648", "reactome": "R-BTA-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071645", "catalyst" ] ], "additional_components": [ "Q8HYR6", "ENSBTAT00000005986", "Q0V8D0", "ENSBTAT00000001829", "Q8HZT6", "ENSBTAT00000026830" ] }, "reaction_10044211": { "compartment": "compartment_12045", "id": "reaction_10044211", "reactome": "R-BTA-211923", "name": "CYP26C1 4-hydroxylates 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5362520", "species_29368", "species_29364" ], "products": [ "species_5362524", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056396" ] }, "reaction_10071668": { "compartment": "compartment_70101", "id": "reaction_10071668", "reactome": "R-BTA-5362525", "name": "CYP26A1,B1,C1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10071666", "species_29368", "species_29364" ], "products": [ "species_29356", "species_10071664", "species_5362521", "species_29366" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "species_215573", "P62964", "ENSBTAT00000017158", "ENSBTAT00000017158", "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10071407": { "compartment": "compartment_7660", "id": "reaction_10071407", "reactome": "R-BTA-5334854", "name": "RAR:RXR binds SUMO-CRABP2:atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071399", "species_10071403" ], "products": [ "species_10071405" ], "modifiers": [], "additional_components": [ "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860" ] }, "reaction_10071397": { "compartment": "compartment_70101", "id": "reaction_10071397", "reactome": "R-BTA-5334827", "name": "SUMO-CRABP2 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071393", "species_5334816" ], "products": [ "species_10071395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158" ] }, "reaction_10072628": { "compartment": "compartment_7660", "id": "reaction_10072628", "reactome": "R-BTA-5634103", "name": "SUMO-CRABP2 dissociates from atRA:RAR:RXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071405" ], "products": [ "species_10072626", "species_10071401" ], "modifiers": [], "additional_components": [ "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "ENSBTAT00000087158" ] }, "reaction_10072630": { "compartment": "compartment_70101", "id": "reaction_10072630", "reactome": "R-BTA-5634104", "name": "SUMO-CRABP2:atRA translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071395" ], "products": [ "species_10071403" ], "modifiers": [], "additional_components": [ "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573" ] }, "reaction_10090456": { "compartment": "compartment_7660", "id": "reaction_10090456", "reactome": "R-BTA-9024334", "name": "Co-repressor complex dissociates from the transcription unit of the ABCA1 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090450" ], "products": [ "species_10090454", "species_10090444" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090559": { "compartment": "compartment_7660", "id": "reaction_10090559", "reactome": "R-BTA-9029551", "name": "NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090454", "species_10047785" ], "products": [ "species_10090557" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090563": { "compartment": "compartment_7660", "id": "reaction_10090563", "reactome": "R-BTA-9029561", "name": "NCOA1 recruits EP300 to the ABCA1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10090557" ], "products": [ "species_10090561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10090452": { "compartment": "compartment_7660", "id": "reaction_10090452", "reactome": "R-BTA-9024326", "name": "Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090448", "species_9024383" ], "products": [ "species_10090450" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090555": { "compartment": "compartment_7660", "id": "reaction_10090555", "reactome": "R-BTA-9029517", "name": "Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090551", "species_9024383" ], "products": [ "species_10090553" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090571": { "compartment": "compartment_7660", "id": "reaction_10090571", "reactome": "R-BTA-9029580", "name": "NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090565", "species_10047785" ], "products": [ "species_10090569" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090567": { "compartment": "compartment_7660", "id": "reaction_10090567", "reactome": "R-BTA-9029566", "name": "Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090553" ], "products": [ "species_10044694", "species_10090565" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090712": { "compartment": "compartment_7660", "id": "reaction_10090712", "reactome": "R-BTA-9038029", "name": "27-hydroxysterol binds ESR1, ESR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045570", "species_9024328" ], "products": [ "species_10090710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005899", "species_9024328", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10092314": { "compartment": "compartment_7660", "id": "reaction_10092314", "reactome": "R-BTA-9709547", "name": "ESTG binds ESR2:chaperone complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086682", "species_1254400" ], "products": [ "species_10086684" ], "modifiers": [], "additional_components": [ "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180", "species_1254400", "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180" ] }, "reaction_10089761": { "compartment": "compartment_7660", "id": "reaction_10089761", "reactome": "R-BTA-9011981", "name": "EP300 is recruited to MYC and BCL2 genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10089757" ], "products": [ "species_10089759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10091115": { "compartment": "compartment_876", "id": "reaction_10091115", "reactome": "R-BTA-9624272", "name": "MMPs cleave HB-EGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091106" ], "products": [ "species_10091108", "species_10040221" ], "modifiers": [ [ "species_10091110", "catalyst" ], [ "species_10091113", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000029015", "ENSBTAT00000029015", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10091275": { "compartment": "compartment_876", "id": "reaction_10091275", "reactome": "R-BTA-9632918", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091269" ], "products": [ "species_10091273" ], "modifiers": [], "additional_components": [ "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091260": { "compartment": "compartment_876", "id": "reaction_10091260", "reactome": "R-BTA-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091252", "species_113592" ], "products": [ "species_29370", "species_10091257" ], "modifiers": [ [ "species_10091252", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10091271": { "compartment": "compartment_876", "id": "reaction_10091271", "reactome": "R-BTA-9632906", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040312", "species_10091257" ], "products": [ "species_10091269" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10091151": { "compartment": "compartment_876", "id": "reaction_10091151", "reactome": "R-BTA-9625482", "name": "PTK2 binds activated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043033" ], "products": [ "species_10091149" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000085237", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091156": { "compartment": "compartment_876", "id": "reaction_10091156", "reactome": "R-BTA-9625487", "name": "PTK2 autophosphorylates downstream of EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091149" ], "products": [ "species_29370", "species_10091153" ], "modifiers": [ [ "species_10091149", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091118": { "compartment": "compartment_7660", "id": "reaction_10091118", "reactome": "R-BTA-9624527", "name": "AKT-phosphorylated FOXO3 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042685" ], "products": [ "species_10091011" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10091267": { "compartment": "compartment_7660", "id": "reaction_10091267", "reactome": "R-BTA-9632873", "name": "p-S10 CDKN1B translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091263" ], "products": [ "species_10091265" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "ENSBTAT00000017629" ] }, "reaction_10091158": { "compartment": "compartment_876", "id": "reaction_10091158", "reactome": "R-BTA-9625813", "name": "S1P binds S1PR3 in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5218688", "species_10046309" ], "products": [ "species_10091113" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015111", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10086662": { "compartment": "compartment_7660", "id": "reaction_10086662", "reactome": "R-BTA-8939201", "name": "ESR dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086658" ], "products": [ "species_10086660" ], "modifiers": [], "additional_components": [ "species_1254400", "Q9XSB5", "ENSBTAT00000005899", "species_1254400", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10086575": { "compartment": "compartment_984", "id": "reaction_10086575", "reactome": "R-BTA-8937631", "name": "CRHR2-2 binds CRH,UCN,UCN2,UCN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10086571" ], "products": [ "species_10086573" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10048270": { "compartment": "compartment_984", "id": "reaction_10048270", "reactome": "R-BTA-420173", "name": "CRHR1,CRHR2-1 binds CRH,UCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10048266" ], "products": [ "species_10048268" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10049681": { "compartment": "compartment_984", "id": "reaction_10049681", "reactome": "R-BTA-444773", "name": "EGF-TM7 receptors bind chondroitin sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444761", "species_10049677" ], "products": [ "species_10049679" ], "modifiers": [], "additional_components": [ "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "species_444761" ] }, "reaction_10051907": { "compartment": "compartment_876", "id": "reaction_10051907", "reactome": "R-BTA-879674", "name": "CD97 binds CD55", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049671", "species_10051903" ], "products": [ "species_10051905" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081916", "ENSBTAT00000078403", "A0A3Q1LQX2", "ENSBTAT00000078403", "A0A3Q1M0R0", "ENSBTAT00000081916" ] }, "reaction_10086565": { "compartment": "compartment_984", "id": "reaction_10086565", "reactome": "R-BTA-8937613", "name": "CRHBP binds CRH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086561", "species_10048266" ], "products": [ "species_10086563" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026905", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A7MBA3", "ENSBTAT00000026905" ] }, "reaction_10048248": { "compartment": "compartment_984", "id": "reaction_10048248", "reactome": "R-BTA-420123", "name": "Glucagon-like receptor 2 binds GLP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048244", "species_10048242" ], "products": [ "species_10048246" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000006662", "E1BAY1", "ENSBTAT00000006662", "P01272", "ENSBTAT00000000972" ] }, "reaction_10048282": { "compartment": "compartment_984", "id": "reaction_10048282", "reactome": "R-BTA-420202", "name": "Secretin receptor binds secretin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048278", "species_10048274" ], "products": [ "species_10048280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071185", "ENSBTAT00000079270", "A0A3Q1MB83", "ENSBTAT00000079270", "A0A3Q1M5G0", "ENSBTAT00000071185" ] }, "reaction_10048304": { "compartment": "compartment_984", "id": "reaction_10048304", "reactome": "R-BTA-420233", "name": "VIP receptors bind VIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048290", "species_10048300" ], "products": [ "species_10048302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017827", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "P81401", "ENSBTAT00000017827" ] }, "reaction_10038918": { "compartment": "compartment_984", "id": "reaction_10038918", "reactome": "R-BTA-163625", "name": "Glucagon binds to Glucagon receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038912", "species_10038908" ], "products": [ "species_10038916" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "ENSBTAT00000000972", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10048326": { "compartment": "compartment_984", "id": "reaction_10048326", "reactome": "R-BTA-420489", "name": "Parathyroid hormone receptor can bind parathyroid hormone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048322", "species_10048312" ], "products": [ "species_10048324" ], "modifiers": [], "additional_components": [ "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408", "ENSBTAT00000061196", "E1B7Q8", "ENSBTAT00000061196", "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408" ] }, "reaction_10091763": { "compartment": "compartment_984", "id": "reaction_10091763", "reactome": "R-BTA-9684627", "name": "CYSLTR1 binds CYSLTR1 antagonists", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_9684615" ], "products": [ "species_10091761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047378": { "compartment": "compartment_984", "id": "reaction_10047378", "reactome": "R-BTA-391937", "name": "UDP/CysLT receptor can bind cysteinyl leukotrienes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_416372" ], "products": [ "species_10046259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047396": { "compartment": "compartment_984", "id": "reaction_10047396", "reactome": "R-BTA-391941", "name": "BLT receptors can bind LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045934", "species_416436" ], "products": [ "species_10045936" ], "modifiers": [], "additional_components": [ "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992" ] }, "reaction_10091812": { "compartment": "compartment_984", "id": "reaction_10091812", "reactome": "R-BTA-9690439", "name": "CYSLTR1 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_416372" ], "products": [ "species_10045864" ], "modifiers": [ [ "species_10091761", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034352", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047398": { "compartment": "compartment_984", "id": "reaction_10047398", "reactome": "R-BTA-391943", "name": "CYSLT2 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038914", "species_416372" ], "products": [ "species_10045866" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10047374": { "compartment": "compartment_984", "id": "reaction_10047374", "reactome": "R-BTA-391935", "name": "DP1 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416911", "species_10047370" ], "products": [ "species_10047372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008808", "A0A452DI56", "ENSBTAT00000008808", "species_416911" ] }, "reaction_10047376": { "compartment": "compartment_984", "id": "reaction_10047376", "reactome": "R-BTA-391936", "name": "EP1 receptor can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10045990" ], "products": [ "species_10045992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046806", "species_391930", "F1MUY4", "ENSBTAT00000046806" ] }, "reaction_10047394": { "compartment": "compartment_984", "id": "reaction_10047394", "reactome": "R-BTA-391940", "name": "EP2 and EP4 receptors can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10047390" ], "products": [ "species_10047392" ], "modifiers": [], "additional_components": [ "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "species_391930" ] }, "reaction_10047380": { "compartment": "compartment_984", "id": "reaction_10047380", "reactome": "R-BTA-391939", "name": "TP receptor can bind thromboxane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391932", "species_10045856" ], "products": [ "species_10045858" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10047366": { "compartment": "compartment_984", "id": "reaction_10047366", "reactome": "R-BTA-391934", "name": "DP2 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046263", "species_416911" ], "products": [ "species_10046265" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066986", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986" ] }, "reaction_10047364": { "compartment": "compartment_984", "id": "reaction_10047364", "reactome": "R-BTA-391905", "name": "Oxoeicosanoid receptor can bind oxoeicosanoid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416428", "species_10046299" ], "products": [ "species_10046301" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005326", "F1MCJ0", "ENSBTAT00000005326", "species_416428" ] }, "reaction_10049657": { "compartment": "compartment_984", "id": "reaction_10049657", "reactome": "R-BTA-444654", "name": "G-protein coupled bile acid receptor binds lithocholic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444840", "species_10049653" ], "products": [ "species_10049655" ], "modifiers": [], "additional_components": [ "species_5357505", "species_193451", "species_176655", "CHEBI:16755", "ENSBTAT00000005120", "Q862A9", "ENSBTAT00000005120", "species_5357505", "species_193451", "species_176655", "CHEBI:16755" ] }, "reaction_10047354": { "compartment": "compartment_984", "id": "reaction_10047354", "reactome": "R-BTA-391375", "name": "Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047350", "species_10047338" ], "products": [ "species_10047352" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524", "ENSBTAT00000052615", "F1N4F6", "ENSBTAT00000052615", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524" ] }, "reaction_10047362": { "compartment": "compartment_984", "id": "reaction_10047362", "reactome": "R-BTA-391377", "name": "Luteinizing hormone receptor can bind LH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041267", "species_10047358" ], "products": [ "species_10047360" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000022047", "A0A140T893", "ENSBTAT00000022047", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10047334": { "compartment": "compartment_984", "id": "reaction_10047334", "reactome": "R-BTA-391372", "name": "Gonadotropin-releasing hormone receptors can bind GNRH I and II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045798", "species_10045788" ], "products": [ "species_10045800" ], "modifiers": [], "additional_components": [ "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "ENSBTAT00000000559", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568" ] }, "reaction_10049659": { "compartment": "compartment_984", "id": "reaction_10049659", "reactome": "R-BTA-444661", "name": "HCAR2 binds HCAR2 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296262", "species_10046459" ], "products": [ "species_10046461" ], "modifiers": [], "additional_components": [ "CHEBI:20067", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230" ] }, "reaction_10048208": { "compartment": "compartment_984", "id": "reaction_10048208", "reactome": "R-BTA-419841", "name": "Light stimulates opsin receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10048204" ], "products": [ "species_10048206" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10048214": { "compartment": "compartment_984", "id": "reaction_10048214", "reactome": "R-BTA-419861", "name": "Melanospin is stimulated by light", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10045850" ], "products": [ "species_10045852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040059", "E1BEK2", "ENSBTAT00000040059", "species_419777" ] }, "reaction_10045180": { "compartment": "compartment_984", "id": "reaction_10045180", "reactome": "R-BTA-373339", "name": "Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045172", "species_10045176" ], "products": [ "species_10045178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013116", "ENSBTAT00000026663", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116" ] }, "reaction_10067358": { "compartment": "compartment_876", "id": "reaction_10067358", "reactome": "R-BTA-3296301", "name": "CCRL2 binds CCL19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049514", "species_10067354" ], "products": [ "species_10067356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016850", "ENSBTAT00000008096", "Q0II78", "ENSBTAT00000008096", "Q3ZBN3", "ENSBTAT00000016850" ] }, "reaction_10045168": { "compartment": "compartment_984", "id": "reaction_10045168", "reactome": "R-BTA-373087", "name": "Receptor CCR6 binds CCL20 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045164", "species_10045160" ], "products": [ "species_10045166" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028430", "ENSBTAT00000037034", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430" ] }, "reaction_10045072": { "compartment": "compartment_984", "id": "reaction_10045072", "reactome": "R-BTA-373061", "name": "Receptors CCR3, 4 and 5 bind CCL5 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045054", "species_10045068" ], "products": [ "species_10045070" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082438", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438" ] }, "reaction_10049520": { "compartment": "compartment_984", "id": "reaction_10049520", "reactome": "R-BTA-443978", "name": "Receptor CCR11 binds CCL19, CCL21 & CCL25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049510", "species_10049516" ], "products": [ "species_10049518" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026082", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "P35350", "ENSBTAT00000026082" ] }, "reaction_10045106": { "compartment": "compartment_984", "id": "reaction_10045106", "reactome": "R-BTA-373074", "name": "Receptor CCR9 binds CCL25 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045102", "species_10045098" ], "products": [ "species_10045104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078248", "ENSBTAT00000007331", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248" ] }, "reaction_10045268": { "compartment": "compartment_984", "id": "reaction_10045268", "reactome": "R-BTA-374214", "name": "Receptors CXCR4 and 7 bind CXCL12 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045264", "species_10045260" ], "products": [ "species_10045266" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980" ] }, "reaction_10083880": { "compartment": "compartment_876", "id": "reaction_10083880", "reactome": "R-BTA-8851352", "name": "CCR8 binds CCL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046469", "species_10045080" ], "products": [ "species_10046471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047653", "ENSBTAT00000020577", "F6RDR3", "ENSBTAT00000020577", "E1BAG6", "ENSBTAT00000047653" ] }, "reaction_10045196": { "compartment": "compartment_984", "id": "reaction_10045196", "reactome": "R-BTA-373358", "name": "Receptor CXCR6 binds CXCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045188", "species_10045192" ], "products": [ "species_10045194" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020855", "ENSBTAT00000024371", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855" ] }, "reaction_10045280": { "compartment": "compartment_984", "id": "reaction_10045280", "reactome": "R-BTA-374248", "name": "Receptor CXCR3 binds ligands CXCL9 to 11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045276", "species_10045272" ], "products": [ "species_10045278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019690", "ENSBTAT00000075648", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690" ] }, "reaction_10049570": { "compartment": "compartment_984", "id": "reaction_10049570", "reactome": "R-BTA-443986", "name": "Receptor ACKR2 binds most inflammatory CC chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049524", "species_10049566" ], "products": [ "species_10049568" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068509", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "A0A3Q1LTZ4", "ENSBTAT00000068509" ] }, "reaction_10045156": { "compartment": "compartment_984", "id": "reaction_10045156", "reactome": "R-BTA-373086", "name": "Receptor CCR10 binds CCL27 and 28 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045142", "species_10045152" ], "products": [ "species_10045154" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025420", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420" ] }, "reaction_10049639": { "compartment": "compartment_984", "id": "reaction_10049639", "reactome": "R-BTA-444523", "name": "CXCR5 binds CXCL13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046161", "species_10046157" ], "products": [ "species_10046163" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011164", "ENSBTAT00000063808", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164" ] }, "reaction_10045094": { "compartment": "compartment_984", "id": "reaction_10045094", "reactome": "R-BTA-373073", "name": "Receptors CCR1, 2 and 8 bind CCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045090", "species_10045086" ], "products": [ "species_10045092" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079349", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349" ] }, "reaction_10091037": { "compartment": "compartment_984", "id": "reaction_10091037", "reactome": "R-BTA-9615249", "name": "ARBs bind AGRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9615246", "species_10045250" ], "products": [ "species_10091035" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063575", "P25104", "ENSBTAT00000063575" ] }, "reaction_10046731": { "compartment": "compartment_984", "id": "reaction_10046731", "reactome": "R-BTA-388468", "name": "AVP(20-28) binds AVPR1A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10045810" ], "products": [ "species_10045816" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10047483": { "compartment": "compartment_984", "id": "reaction_10047483", "reactome": "R-BTA-392263", "name": "AVP(20-28) binds AVPR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10047479" ], "products": [ "species_10047481" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "ENSBTAT00000065044", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10046733": { "compartment": "compartment_984", "id": "reaction_10046733", "reactome": "R-BTA-388503", "name": "Oxytocin receptor bind oxytocin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045970", "species_10045966" ], "products": [ "species_10045972" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026346", "ENSBTAT00000010554", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346" ] }, "reaction_10049661": { "compartment": "compartment_984", "id": "reaction_10049661", "reactome": "R-BTA-444691", "name": "Prokineticin receptors bind prokineticin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046036", "species_10046032" ], "products": [ "species_10046038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013959", "ENSBTAT00000021097", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959" ] }, "reaction_10046729": { "compartment": "compartment_984", "id": "reaction_10046729", "reactome": "R-BTA-383373", "name": "Tachykinin receptor 3 (NK3) binds to neurokinin B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045940", "species_10045944" ], "products": [ "species_10045946" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029067", "ENSBTAT00000021612", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067" ] }, "reaction_10045406": { "compartment": "compartment_984", "id": "reaction_10045406", "reactome": "R-BTA-374787", "name": "GPCR neuropeptide receptor binds neuropeptides B and W", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045398", "species_10045402" ], "products": [ "species_10045404" ], "modifiers": [], "additional_components": [ "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "ENSBTAT00000021510", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382" ] }, "reaction_10045362": { "compartment": "compartment_984", "id": "reaction_10045362", "reactome": "R-BTA-374723", "name": "Nociceptin receptor binds to nociceptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045358", "species_10045354" ], "products": [ "species_10045360" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084136", "ENSBTAT00000000695", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136" ] }, "reaction_10046773": { "compartment": "compartment_984", "id": "reaction_10046773", "reactome": "R-BTA-388605", "name": "POMC(138-176) binds MC2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046769", "species_10046767" ], "products": [ "species_10046771" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010386", "ENSBTAT00000014661", "P34974", "ENSBTAT00000014661", "P01190", "ENSBTAT00000010386" ] }, "reaction_10045332": { "compartment": "compartment_984", "id": "reaction_10045332", "reactome": "R-BTA-374331", "name": "Bradykinin receptors B1 and B2 bind to bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038198", "species_10045328" ], "products": [ "species_10045330" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053071", "ENSBTAT00000078035", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071" ] }, "reaction_10053335": { "compartment": "compartment_876", "id": "reaction_10053335", "reactome": "R-BTA-964800", "name": "Neuromedin-U receptors bind neuromedins U, S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046114", "species_10046110" ], "products": [ "species_10046116" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061371", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371" ] }, "reaction_10054775": { "compartment": "compartment_876", "id": "reaction_10054775", "reactome": "R-BTA-981832", "name": "NMUR2 binds neuromedin-S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046102", "species_10046098" ], "products": [ "species_10046104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048447", "ENSBTAT00000014782", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447" ] }, "reaction_10046953": { "compartment": "compartment_984", "id": "reaction_10046953", "reactome": "R-BTA-389463", "name": "Proteinase-activated receptors can bind thrombin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045984", "species_10037577" ], "products": [ "species_10045986" ], "modifiers": [], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191" ] }, "reaction_10045384": { "compartment": "compartment_984", "id": "reaction_10045384", "reactome": "R-BTA-374758", "name": "Somatostatin receptors bind somatostatin and cortistatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045366", "species_10045380" ], "products": [ "species_10045382" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063299", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299" ] }, "reaction_10046763": { "compartment": "compartment_984", "id": "reaction_10046763", "reactome": "R-BTA-388596", "name": "Melanocortin receptors bind melanocortins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046759", "species_10046737" ], "products": [ "species_10046761" ], "modifiers": [], "additional_components": [ "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049", "ENSBTAT00000010386", "P01190", "ENSBTAT00000010386", "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049" ] }, "reaction_10049645": { "compartment": "compartment_984", "id": "reaction_10049645", "reactome": "R-BTA-444620", "name": "Neuropeptide S receptor binds neuropeptide S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046022", "species_10046026" ], "products": [ "species_10046028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067360", "ENSBTAT00000018290", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360" ] }, "reaction_10049699": { "compartment": "compartment_984", "id": "reaction_10049699", "reactome": "R-BTA-444879", "name": "Relaxin receptor 2 binds relaxin 2 and INSL3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049687", "species_10049695" ], "products": [ "species_10049697" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020135", "O77801", "ENSBTAT00000027848", "O77801", "ENSBTAT00000027848", "E1BKC2", "ENSBTAT00000020135" ] }, "reaction_10049683": { "compartment": "compartment_984", "id": "reaction_10049683", "reactome": "R-BTA-444848", "name": "Relaxin 3 receptor 1 binds relaxin 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046333", "species_10046329" ], "products": [ "species_10046335" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055041", "F1MEV7", "ENSBTAT00000036249", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041" ] }, "reaction_10045292": { "compartment": "compartment_984", "id": "reaction_10045292", "reactome": "R-BTA-374251", "name": "DARC is a non-specific receptor for many chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045284", "species_10045288" ], "products": [ "species_10045290" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004179", "ENSBTAT00000026275", "P79255", "ENSBTAT00000026275", "F1N018", "ENSBTAT00000004179" ] }, "reaction_10045324": { "compartment": "compartment_984", "id": "reaction_10045324", "reactome": "R-BTA-374298", "name": "Opioid receptors bind opioid peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045302", "species_10045320" ], "products": [ "species_10045322" ], "modifiers": [], "additional_components": [ "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209" ] }, "reaction_10046735": { "compartment": "compartment_984", "id": "reaction_10046735", "reactome": "R-BTA-388560", "name": "Endothelin receptors bind endothelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045876", "species_10045886" ], "products": [ "species_10045888" ], "modifiers": [], "additional_components": [ "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571" ] }, "reaction_10046915": { "compartment": "compartment_984", "id": "reaction_10046915", "reactome": "R-BTA-388863", "name": "Neuropeptide Y receptors can bind neuropeptide Y-related peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046293", "species_10046275" ], "products": [ "species_10046295" ], "modifiers": [], "additional_components": [ "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "ENSBTAT00000062944", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149" ] }, "reaction_10046917": { "compartment": "compartment_984", "id": "reaction_10046917", "reactome": "R-BTA-388900", "name": "Neurotensin receptors can bind neurotensins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045950", "species_10045960" ], "products": [ "species_10045962" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006980", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980" ] }, "reaction_10049637": { "compartment": "compartment_984", "id": "reaction_10049637", "reactome": "R-BTA-444498", "name": "Thyrotropin-releasing hormone receptor binds thyrotropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046006", "species_10046002" ], "products": [ "species_10046018" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006982", "ENSBTAT00000026634", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982" ] }, "reaction_10046919": { "compartment": "compartment_984", "id": "reaction_10046919", "reactome": "R-BTA-388981", "name": "The Kiss receptor GPR54 binds kisspeptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045902", "species_10045898" ], "products": [ "species_10045904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028248", "ENSBTAT00000073562", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248" ] }, "reaction_10045350": { "compartment": "compartment_984", "id": "reaction_10045350", "reactome": "R-BTA-374337", "name": "Apelin receptor binds to apelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045346", "species_10045336" ], "products": [ "species_10045348" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039541", "ENSBTAT00000026630", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541" ] }, "reaction_10047864": { "compartment": "compartment_984", "id": "reaction_10047864", "reactome": "R-BTA-417890", "name": "P2Y5 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045826", "species_417891" ], "products": [ "species_10045828" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008730", "species_417891", "A6QL49", "ENSBTAT00000008730" ] }, "reaction_10047851": { "compartment": "compartment_984", "id": "reaction_10047851", "reactome": "R-BTA-417820", "name": "P2Y9 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045838", "species_417891" ], "products": [ "species_10045840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004269", "species_417891", "A4IFV1", "ENSBTAT00000004269" ] }, "reaction_10047866": { "compartment": "compartment_984", "id": "reaction_10047866", "reactome": "R-BTA-417896", "name": "P2Y6 receptor can bind to UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417888", "species_10045832" ], "products": [ "species_10045834" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057184", "F1MTB2", "ENSBTAT00000057184", "species_205687" ] }, "reaction_10047853": { "compartment": "compartment_984", "id": "reaction_10047853", "reactome": "R-BTA-417825", "name": "P2Y11 receptor can bind to ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114570", "species_10045976" ], "products": [ "species_10045978" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018000", "F1MU50", "ENSBTAT00000018000", "species_113592" ] }, "reaction_10047868": { "compartment": "compartment_984", "id": "reaction_10047868", "reactome": "R-BTA-417898", "name": "P2Y4 receptor can bind to UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046215", "species_417877" ], "products": [ "species_10046217" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054975", "species_29494", "F1MDW9", "ENSBTAT00000054975" ] }, "reaction_10090956": { "compartment": "compartment_984", "id": "reaction_10090956", "reactome": "R-BTA-9611277", "name": "P2RY12 antagonists bind P2RY12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611319", "species_10046221" ], "products": [ "species_10047855" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047870": { "compartment": "compartment_984", "id": "reaction_10047870", "reactome": "R-BTA-417908", "name": "P2RY1 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10045820" ], "products": [ "species_10045822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001919", "species_29370", "P48042", "ENSBTAT00000001919" ] }, "reaction_10047857": { "compartment": "compartment_984", "id": "reaction_10047857", "reactome": "R-BTA-417829", "name": "P2RY12 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10046221" ], "products": [ "species_10046223" ], "modifiers": [ [ "species_10047855", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047989": { "compartment": "compartment_984", "id": "reaction_10047989", "reactome": "R-BTA-418918", "name": "The UDP/CysLT (P2Y17) receptor can bind UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_417888" ], "products": [ "species_10045894" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_205687", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047860": { "compartment": "compartment_984", "id": "reaction_10047860", "reactome": "R-BTA-417842", "name": "P2Y10 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045844", "species_417891" ], "products": [ "species_10045846" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011278", "species_417891", "G3X6Q0", "ENSBTAT00000011278" ] }, "reaction_10047862": { "compartment": "compartment_984", "id": "reaction_10047862", "reactome": "R-BTA-417858", "name": "P2Y14 receptor can bind to UDP-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046227", "species_417855" ], "products": [ "species_10046229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027950", "species_29410", "Q3SX17", "ENSBTAT00000027950" ] }, "reaction_10047987": { "compartment": "compartment_984", "id": "reaction_10047987", "reactome": "R-BTA-418904", "name": "A1 and A3 receptors bind adenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046239", "species_83908" ], "products": [ "species_10046241" ], "modifiers": [], "additional_components": [ "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690" ] }, "reaction_10048003": { "compartment": "compartment_984", "id": "reaction_10048003", "reactome": "R-BTA-418925", "name": "ADORA2A,B bind Ade-Rib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047999", "species_83908" ], "products": [ "species_10048001" ], "modifiers": [], "additional_components": [ "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466" ] }, "reaction_10078536": { "compartment": "compartment_876", "id": "reaction_10078536", "reactome": "R-BTA-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_417891" ], "products": [ "species_109277", "species_6797635" ], "modifiers": [ [ "species_10078533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025329" ] }, "reaction_10048176": { "compartment": "compartment_984", "id": "reaction_10048176", "reactome": "R-BTA-419389", "name": "LPA-binding receptors bind LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045922", "species_417891" ], "products": [ "species_10045924" ], "modifiers": [], "additional_components": [ "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152" ] }, "reaction_10048180": { "compartment": "compartment_984", "id": "reaction_10048180", "reactome": "R-BTA-419428", "name": "S1PR2-5 bind S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_10046319" ], "products": [ "species_10046321" ], "modifiers": [], "additional_components": [ "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10049663": { "compartment": "compartment_984", "id": "reaction_10049663", "reactome": "R-BTA-444731", "name": "GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10046074" ], "products": [ "species_10046076" ], "modifiers": [], "additional_components": [ "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529" ] }, "reaction_10084702": { "compartment": "compartment_984", "id": "reaction_10084702", "reactome": "R-BTA-8862700", "name": "CMKLR1 binds Resolvin E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023982", "species_10084698" ], "products": [ "species_10084700" ], "modifiers": [], "additional_components": [ "CHEBI:81559", "species_9022660", "ENSBTAT00000029488", "B9VR26", "ENSBTAT00000029488", "CHEBI:81559", "species_9022660" ] }, "reaction_10051217": { "compartment": "compartment_984", "id": "reaction_10051217", "reactome": "R-BTA-517536", "name": "N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_517533", "species_10046339" ], "products": [ "species_10046341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007469", "Q3T0E9", "ENSBTAT00000007469", "species_517533" ] }, "reaction_10048178": { "compartment": "compartment_984", "id": "reaction_10048178", "reactome": "R-BTA-419426", "name": "Cannabinoid receptors can bind cannabinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444560", "species_10046255" ], "products": [ "species_10046257" ], "modifiers": [], "additional_components": [ "species_5693754", "species_426030", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030" ] }, "reaction_10053333": { "compartment": "compartment_984", "id": "reaction_10053333", "reactome": "R-BTA-964773", "name": "OXGR1 binds 2OG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_561075", "species_10046447" ], "products": [ "species_10046449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035454", "F1MYN3", "ENSBTAT00000035454", "species_113594" ] }, "reaction_10067350": { "compartment": "compartment_876", "id": "reaction_10067350", "reactome": "R-BTA-3296244", "name": "SUCNR1 binds SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433123", "species_10046441" ], "products": [ "species_10046443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068791", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536" ] }, "reaction_10049641": { "compartment": "compartment_984", "id": "reaction_10049641", "reactome": "R-BTA-444572", "name": "Zinc is an agonist of GPR39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046134", "species_158417" ], "products": [ "species_10046136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065884", "species_29426", "G3MWJ9", "ENSBTAT00000065884" ] }, "reaction_10048172": { "compartment": "compartment_984", "id": "reaction_10048172", "reactome": "R-BTA-419334", "name": "Melatonin receptors can bind melatonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419339", "species_10046269" ], "products": [ "species_10046271" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068939", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339" ] }, "reaction_10081580": { "compartment": "compartment_984", "id": "reaction_10081580", "reactome": "R-BTA-6805205", "name": "GPR35 binds kynurenic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6805204", "species_10081576" ], "products": [ "species_10081578" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021281", "F1N600", "ENSBTAT00000021281", "species_6805204" ] }, "reaction_10067362": { "compartment": "compartment_876", "id": "reaction_10067362", "reactome": "R-BTA-3296309", "name": "HCAR3 binds HCAR3 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296330", "species_10046463" ], "products": [ "species_10046465" ], "modifiers": [], "additional_components": [ "CHEBI:37098", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:37098", "species_197230" ] }, "reaction_10067364": { "compartment": "compartment_876", "id": "reaction_10067364", "reactome": "R-BTA-3296326", "name": "HCAR1 binds LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046453", "species_373863" ], "products": [ "species_10046455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001202", "species_373863", "B9UM28", "ENSBTAT00000001202" ] }, "reaction_10048174": { "compartment": "compartment_984", "id": "reaction_10048174", "reactome": "R-BTA-419351", "name": "PAF receptor binds platelet activating factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419375", "species_10045996" ], "products": [ "species_10045998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038757", "Q9TTY5", "ENSBTAT00000038757", "species_419375" ] }, "reaction_10083937": { "compartment": "compartment_984", "id": "reaction_10083937", "reactome": "R-BTA-8851679", "name": "GPR183 binds 7alpha,25-dihydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851675", "species_10046483" ], "products": [ "species_10046485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007471", "Q1RMI1", "ENSBTAT00000007471", "species_192184" ] }, "reaction_10049643": { "compartment": "compartment_984", "id": "reaction_10049643", "reactome": "R-BTA-444606", "name": "T1R2/T1R3 dimer is a sweet taste receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046501", "species_444679" ], "products": [ "species_10046503" ], "modifiers": [], "additional_components": [ "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207" ] }, "reaction_10045138": { "compartment": "compartment_984", "id": "reaction_10045138", "reactome": "R-BTA-373075", "name": "Metabotropic glutamate receptors bind glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10045134" ], "products": [ "species_10045136" ], "modifiers": [], "additional_components": [ "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "species_210382" ] }, "reaction_10067348": { "compartment": "compartment_876", "id": "reaction_10067348", "reactome": "R-BTA-3296233", "name": "T2Rs bind bitter-tasting compounds", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046435", "species_3296423" ], "products": [ "species_10046437" ], "modifiers": [], "additional_components": [ "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537" ] }, "reaction_10089211": { "compartment": "compartment_876", "id": "reaction_10089211", "reactome": "R-BTA-8982019", "name": "Active G alpha (i)i1/i2/i3 binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039640", "species_10089193" ], "products": [ "species_10089209" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089197": { "compartment": "compartment_876", "id": "reaction_10089197", "reactome": "R-BTA-8982012", "name": "G alpha (i):RGS dissociates to inactive G alpha (i)i1/i2/i3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089195" ], "products": [ "species_10039660", "species_10089193" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10088940": { "compartment": "compartment_876", "id": "reaction_10088940", "reactome": "R-BTA-8964242", "name": "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088932", "species_113592" ], "products": [ "species_29370", "species_10088937" ], "modifiers": [ [ "species_10088932", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088942": { "compartment": "compartment_70101", "id": "reaction_10088942", "reactome": "R-BTA-8964329", "name": "G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088937" ], "products": [ "species_10088935", "species_10039640" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089214": { "compartment": "compartment_876", "id": "reaction_10089214", "reactome": "R-BTA-8982020", "name": "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089209" ], "products": [ "species_29372", "species_10089195" ], "modifiers": [ [ "species_10089209", "catalyst" ] ], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10048370": { "compartment": "compartment_70101", "id": "reaction_10048370", "reactome": "R-BTA-420883", "name": "Opsins act as GEFs for G alpha-t", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10048361" ], "products": [ "species_29420", "species_10048367" ], "modifiers": [ [ "species_10048206", "catalyst" ] ], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "P63212", "ENSBTAT00000003959", "species_29420", "P04695", "ENSBTAT00000023990", "P04695", "ENSBTAT00000023990", "species_29438", "P63212", "ENSBTAT00000003959", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10037037": { "compartment": "compartment_70101", "id": "reaction_10037037", "reactome": "R-BTA-111962", "name": "PDE4A,C,D hydrolyse cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037034", "catalyst" ] ], "additional_components": [ "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100" ] }, "reaction_10039658": { "compartment": "compartment_876", "id": "reaction_10039658", "reactome": "R-BTA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10036997" ], "products": [ "species_10039655" ], "modifiers": [ [ "species_10036997", "catalyst" ] ], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10039674": { "compartment": "compartment_876", "id": "reaction_10039674", "reactome": "R-BTA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039655" ], "products": [ "species_29372", "species_10039669" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039667": { "compartment": "compartment_876", "id": "reaction_10039667", "reactome": "R-BTA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039671": { "compartment": "compartment_876", "id": "reaction_10039671", "reactome": "R-BTA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039669" ], "products": [ "species_10036997", "species_10039646" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420" ] }, "reaction_10036959": { "compartment": "compartment_70101", "id": "reaction_10036959", "reactome": "R-BTA-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10037045": { "compartment": "compartment_70101", "id": "reaction_10037045", "reactome": "R-BTA-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036956" ], "products": [ "species_29372", "species_10037043", "species_10036942" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "ENSBTAT00000074229" ] }, "reaction_10039676": { "compartment": "compartment_876", "id": "reaction_10039676", "reactome": "R-BTA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039662" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039664": { "compartment": "compartment_876", "id": "reaction_10039664", "reactome": "R-BTA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039662" ], "products": [ "species_10036997", "species_10039646", "species_10039660" ], "modifiers": [], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10039651": { "compartment": "compartment_876", "id": "reaction_10039651", "reactome": "R-BTA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039648" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039653": { "compartment": "compartment_876", "id": "reaction_10039653", "reactome": "R-BTA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10039642" ], "products": [ "species_10039644" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10046534": { "compartment": "compartment_947587", "id": "reaction_10046534", "reactome": "R-BTA-380073", "name": "Liganded Gi-activating GPCR acts as a GEF for Gi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046509" ], "products": [ "species_29420", "species_10046513" ], "modifiers": [ [ "species_10046509", "catalyst" ], [ "species_10046532", "inhibitor" ] ], "additional_components": [ "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "A0A3Q1MMQ2", "ENSBTAT00000081300", "A0A3Q1MKT3", "ENSBTAT00000078547" ] }, "reaction_10089224": { "compartment": "compartment_876", "id": "reaction_10089224", "reactome": "R-BTA-8982026", "name": "G alpha (q):RGS dissociates to inactive G alpha (q)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089219" ], "products": [ "species_10089199", "species_10037355" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420" ] }, "reaction_10047979": { "compartment": "compartment_876", "id": "reaction_10047979", "reactome": "R-BTA-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954" ], "products": [ "species_10037355" ], "modifiers": [ [ "species_10036954", "catalyst" ], [ "species_10047977", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "F1N7R3", "ENSBTAT00000005904" ] }, "reaction_10048632": { "compartment": "compartment_876", "id": "reaction_10048632", "reactome": "R-BTA-426209", "name": "DAG activation of TRPC channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048628", "species_114519" ], "products": [ "species_10048630" ], "modifiers": [], "additional_components": [ "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10048543": { "compartment": "compartment_70101", "id": "reaction_10048543", "reactome": "R-BTA-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519", "species_10048539" ], "products": [ "species_10048541" ], "modifiers": [], "additional_components": [ "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "species_6797635" ] }, "reaction_10048587": { "compartment": "compartment_70101", "id": "reaction_10048587", "reactome": "R-BTA-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426030" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10048584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073448" ] }, "reaction_10048580": { "compartment": "compartment_876", "id": "reaction_10048580", "reactome": "R-BTA-426032", "name": "DAG is metabolized by DAGL to 2-AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519" ], "products": [ "species_426026", "species_426030" ], "modifiers": [ [ "species_10048577", "catalyst" ] ], "additional_components": [ "E1BBV2", "ENSBTAT00000018523", "F6RA94", "ENSBTAT00000012173" ] }, "reaction_10076743": { "compartment": "compartment_876", "id": "reaction_10076743", "reactome": "R-BTA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10076740", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022100" ] }, "reaction_10048660": { "compartment": "compartment_70101", "id": "reaction_10048660", "reactome": "R-BTA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10048657", "catalyst" ] ], "additional_components": [ "F1MCG9", "ENSBTAT00000031198", "A0A3Q1NJA6", "ENSBTAT00000066461", "E1BGA9", "ENSBTAT00000022905", "A0A3Q1LYT4", "ENSBTAT00000075621", "A0A3Q1N4W0", "ENSBTAT00000080144" ] }, "reaction_10037549": { "compartment": "compartment_876", "id": "reaction_10037549", "reactome": "R-BTA-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037544" ], "products": [ "species_10037546" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "species_6810412", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "species_6797635", "species_114520", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10047823": { "compartment": "compartment_70101", "id": "reaction_10047823", "reactome": "R-BTA-400586", "name": "G alpha (q) binds to Trio family RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954", "species_10047819" ], "products": [ "species_10047821" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10064910": { "compartment": "compartment_984", "id": "reaction_10064910", "reactome": "R-BTA-2179387", "name": "Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040221", "species_10040201" ], "products": [ "species_10064908" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10064915": { "compartment": "compartment_70101", "id": "reaction_10064915", "reactome": "R-BTA-2179407", "name": "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10064912", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10064919": { "compartment": "compartment_70101", "id": "reaction_10064919", "reactome": "R-BTA-2179415", "name": "GRB2:SOS1 binds to HBEGF:p-Y-EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10064908" ], "products": [ "species_10064912" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10089203": { "compartment": "compartment_876", "id": "reaction_10089203", "reactome": "R-BTA-8982017", "name": "Active G alpha (q) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089199", "species_10036954" ], "products": [ "species_10089201" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10046149": { "compartment": "compartment_70101", "id": "reaction_10046149", "reactome": "R-BTA-379048", "name": "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046140" ], "products": [ "species_29420", "species_10046142" ], "modifiers": [ [ "species_10046146", "catalyst" ] ], "additional_components": [ "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "species_266013", "A7MBH4", "ENSBTAT00000023275", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10089222": { "compartment": "compartment_876", "id": "reaction_10089222", "reactome": "R-BTA-8982025", "name": "G alpha (q) in G (q):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089201" ], "products": [ "species_29372", "species_10089219" ], "modifiers": [ [ "species_10089201", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10047947": { "compartment": "compartment_70101", "id": "reaction_10047947", "reactome": "R-BTA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10047944", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100", "A0A3Q1M3R2", "ENSBTAT00000085287", "A0A3Q1M5L1", "ENSBTAT00000082666" ] }, "reaction_10089226": { "compartment": "compartment_876", "id": "reaction_10089226", "reactome": "R-BTA-8982641", "name": "ADRB2:GRK complex dissociates to Phosphorylated ADRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083948" ], "products": [ "species_10083941", "species_10084012" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789" ] }, "reaction_10089228": { "compartment": "compartment_876", "id": "reaction_10089228", "reactome": "R-BTA-8982645", "name": "GRKs bind ADRB2:Catecholamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083941", "species_10051595" ], "products": [ "species_10083943" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10091247": { "compartment": "compartment_70101", "id": "reaction_10091247", "reactome": "R-BTA-9629675", "name": "PDE3A hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10091244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072849" ] }, "reaction_10083951": { "compartment": "compartment_876", "id": "reaction_10083951", "reactome": "R-BTA-8851797", "name": "ADRB2 in ADRB2:GRK complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083943", "species_113592" ], "products": [ "species_29370", "species_10083948" ], "modifiers": [ [ "species_10083943", "catalyst" ] ], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10084016": { "compartment": "compartment_70101", "id": "reaction_10084016", "reactome": "R-BTA-8852167", "name": "ADRB2:Catecholamine binds ARRB1, ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10084012" ], "products": [ "species_10084014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092055": { "compartment": "compartment_70101", "id": "reaction_10092055", "reactome": "R-BTA-9705507", "name": "PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10092052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10047498": { "compartment": "compartment_70101", "id": "reaction_10047498", "reactome": "R-BTA-392300", "name": "G beta:gamma activated PI3Kgamma converts PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047495", "catalyst" ] ], "additional_components": [ "P63212", "ENSBTAT00000003959", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10043315": { "compartment": "compartment_876", "id": "reaction_10043315", "reactome": "R-BTA-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10037311" ], "products": [ "species_10043313" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005600", "P61585", "ENSBTAT00000005600", "species_179838" ] }, "reaction_10088962": { "compartment": "compartment_70101", "id": "reaction_10088962", "reactome": "R-BTA-8964619", "name": "PAK1 binds ARHGEF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047596", "species_10048105" ], "products": [ "species_10088960" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080749", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10051656": { "compartment": "compartment_70101", "id": "reaction_10051656", "reactome": "R-BTA-749453", "name": "Liganded Gz-activating GPCR acts as a GEF for Gz", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051649" ], "products": [ "species_29420", "species_10051653" ], "modifiers": [ [ "species_10051649", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959" ] }, "reaction_10047468": { "compartment": "compartment_876", "id": "reaction_10047468", "reactome": "R-BTA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036997", "species_10047464" ], "products": [ "species_10047466" ], "modifiers": [], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10089167": { "compartment": "compartment_876", "id": "reaction_10089167", "reactome": "R-BTA-8981892", "name": "Active G alpha (z) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089163", "species_10047464" ], "products": [ "species_10089165" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089217": { "compartment": "compartment_876", "id": "reaction_10089217", "reactome": "R-BTA-8982021", "name": "G alpha (z) in G alpha (z):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089165" ], "products": [ "species_29372", "species_10089205" ], "modifiers": [ [ "species_10089165", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089207": { "compartment": "compartment_876", "id": "reaction_10089207", "reactome": "R-BTA-8982018", "name": "G alpha (z):RGS complex dissociates to give inactive G alpha (z)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089205" ], "products": [ "species_10051645", "species_10089163" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10048170": { "compartment": "compartment_70101", "id": "reaction_10048170", "reactome": "R-BTA-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047839" ], "products": [ "species_29420", "species_10047841" ], "modifiers": [ [ "species_10048167", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "E1B9G8", "ENSBTAT00000014311", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1M8D9", "ENSBTAT00000071999", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LQ45", "ENSBTAT00000078928", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1MA97", "ENSBTAT00000081198", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1LXW7", "ENSBTAT00000081961", "A0A3Q1MA22", "ENSBTAT00000069238", "Q08DA6", "ENSBTAT00000011773", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417", "F1N7C3", "ENSBTAT00000015471", "A0A3Q1MA88", "ENSBTAT00000069507", "Q58CS5", "ENSBTAT00000009131", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1N5H1", "ENSBTAT00000068004" ] }, "reaction_10047552": { "compartment": "compartment_70101", "id": "reaction_10047552", "reactome": "R-BTA-398184", "name": "LARG activation by G alpha 12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047548", "species_10047544" ], "products": [ "species_10047550" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081099", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "A0A3Q1MN47", "ENSBTAT00000081099" ] }, "reaction_10051667": { "compartment": "compartment_70101", "id": "reaction_10051667", "reactome": "R-BTA-751029", "name": "Liganded G12/13-activating GPCR acts as a GEF for G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051664" ], "products": [ "species_29420", "species_10051660" ], "modifiers": [ [ "species_10051664", "catalyst" ] ], "additional_components": [ "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10037330": { "compartment": "compartment_70101", "id": "reaction_10037330", "reactome": "R-BTA-114544", "name": "p115-RhoGEF activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10037327", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10037332": { "compartment": "compartment_70101", "id": "reaction_10037332", "reactome": "R-BTA-114548", "name": "G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037325", "species_10037321" ], "products": [ "species_10037327" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066417", "G5E6P3", "ENSBTAT00000062941", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10047956": { "compartment": "compartment_876", "id": "reaction_10047956", "reactome": "R-BTA-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047544" ], "products": [ "species_10047953" ], "modifiers": [ [ "species_10047544", "catalyst" ] ], "additional_components": [ "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "species_29420", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757" ] }, "reaction_10072123": { "compartment": "compartment_5263228", "id": "reaction_10072123", "reactome": "R-BTA-5610733", "name": "KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072119", "species_10072115" ], "products": [ "species_10072121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075908", "species_29438", "species_29420", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908" ] }, "reaction_10072154": { "compartment": "compartment_24337", "id": "reaction_10072154", "reactome": "R-BTA-5610763", "name": "PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072144" ], "products": [ "species_10072148" ], "modifiers": [ [ "species_10072152", "inhibitor" ] ], "additional_components": [ "E1BE57", "ENSBTAT00000017670", "E1BE57", "ENSBTAT00000017670", "ENSBTAT00000064817" ] }, "reaction_10072220": { "compartment": "compartment_5263228", "id": "reaction_10072220", "reactome": "R-BTA-5610767", "name": "The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072218", "catalyst" ], [ "species_10072121", "catalyst" ], [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BKE3", "ENSBTAT00000035821", "A0A3Q1MNB3", "ENSBTAT00000078675", "Q32KR5", "ENSBTAT00000087155", "A0A452DIR3", "ENSBTAT00000007606", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308" ] }, "reaction_10072081": { "compartment": "compartment_70101", "id": "reaction_10072081", "reactome": "R-BTA-5610723", "name": "GLI proteins bind SUFU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072077", "species_10072073" ], "products": [ "species_10072079" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810" ] }, "reaction_10072138": { "compartment": "compartment_5263232", "id": "reaction_10072138", "reactome": "R-BTA-5610742", "name": "SCF(beta-TrCP) ubiquitinates p-GLI1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072130", "species_10033408" ], "products": [ "species_10072135" ], "modifiers": [ [ "species_10043873", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10072199": { "compartment": "compartment_5263232", "id": "reaction_10072199", "reactome": "R-BTA-5610766", "name": "The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072165" ], "products": [ "species_10072173" ], "modifiers": [ [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ], [ "species_10072187", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308", "ENSBTAT00000036487" ] }, "reaction_10072713": { "compartment": "compartment_7660", "id": "reaction_10072713", "reactome": "R-BTA-5635856", "name": "SPOP:CUL3:RBX1 ubiquitinates GLI2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072710", "species_10036828" ], "products": [ "species_10072708" ], "modifiers": [ [ "species_10072710", "catalyst" ] ], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660" ] }, "reaction_10072715": { "compartment": "compartment_5263228", "id": "reaction_10072715", "reactome": "R-BTA-5635860", "name": "GLI:SUFU translocates to the ciliary tip in response to Hh signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072119", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "ENSBTAT00000075908" ] }, "reaction_10072685": { "compartment": "compartment_7660", "id": "reaction_10072685", "reactome": "R-BTA-5635845", "name": "GLI proteins bind CDC73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072669", "species_10072681" ], "products": [ "species_10072683" ], "modifiers": [], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "ENSBTAT00000022205", "E1BPQ8", "ENSBTAT00000022205", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10072606": { "compartment": "compartment_261122", "id": "reaction_10072606", "reactome": "R-BTA-5632677", "name": "PTCH is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072602" ], "products": [ "species_10072604" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064817", "ENSBTAT00000064817" ] }, "reaction_10072720": { "compartment": "compartment_261122", "id": "reaction_10072720", "reactome": "R-BTA-5635865", "name": "SMURF1/2 dissociates from ub-PTCH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072718" ], "products": [ "species_10042973", "species_10072602" ], "modifiers": [], "additional_components": [ "G3N1D5", "ENSBTAT00000064817", "F1MLS5", "ENSBTAT00000043725", "ENSBTAT00000043725", "ENSBTAT00000064817" ] }, "reaction_10072677": { "compartment": "compartment_5263228", "id": "reaction_10072677", "reactome": "R-BTA-5635843", "name": "GLI translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072675" ], "products": [ "species_10072663" ], "modifiers": [], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10074038": { "compartment": "compartment_876", "id": "reaction_10074038", "reactome": "R-BTA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BG59", "ENSBTAT00000029159", "A0A3Q1MPT9", "ENSBTAT00000086336", "A0A3Q1MD11", "ENSBTAT00000081804", "A0A3Q1M7J4", "ENSBTAT00000085129", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A452DJB1", "ENSBTAT00000044847", "A0A452DHX3", "ENSBTAT00000003498", "F1N5N3", "ENSBTAT00000021391", "F1MP52", "ENSBTAT00000015112", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LSU3", "ENSBTAT00000068365", "species_6797635", "A0A3Q1N010", "ENSBTAT00000084300" ] }, "reaction_10091515": { "compartment": "compartment_876", "id": "reaction_10091515", "reactome": "R-BTA-9647994", "name": "RAS proteins are depalmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039726" ], "products": [ "species_8848337", "species_10091512" ], "modifiers": [ [ "species_10091502", "catalyst" ], [ "species_10091504", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091458": { "compartment": "compartment_12045", "id": "reaction_10091458", "reactome": "R-BTA-9647977", "name": "ICMT methylates S-Farn RAS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10091448" ], "products": [ "species_10091454", "species_71285" ], "modifiers": [ [ "species_10077880", "catalyst" ], [ "species_10091456", "inhibitor" ] ], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29426", "G3N1V4", "ENSBTAT00000064297", "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10091490": { "compartment": "compartment_20699", "id": "reaction_10091490", "reactome": "R-BTA-9647982", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091454", "species_200993" ], "products": [ "species_10091477", "species_76194" ], "modifiers": [ [ "species_10091487", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "Q5EA55", "ENSBTAT00000069302", "Q58DA8", "ENSBTAT00000075844" ] }, "reaction_10091506": { "compartment": "compartment_876", "id": "reaction_10091506", "reactome": "R-BTA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10091502" ], "products": [ "species_10091504" ], "modifiers": [], "additional_components": [ "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091479": { "compartment": "compartment_876", "id": "reaction_10091479", "reactome": "R-BTA-9647980", "name": "mature RAS proteins translocate to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091477" ], "products": [ "species_10039726" ], "modifiers": [], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897" ] }, "reaction_10091527": { "compartment": "compartment_876", "id": "reaction_10091527", "reactome": "R-BTA-9649733", "name": "mature p21 RAS binds GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10039726" ], "products": [ "species_10040312" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10074088": { "compartment": "compartment_876", "id": "reaction_10074088", "reactome": "R-BTA-5672969", "name": "Phosphorylation of RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074042" ], "products": [ "species_29370", "species_10074065" ], "modifiers": [ [ "species_10074085", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073930": { "compartment": "compartment_70101", "id": "reaction_10073930", "reactome": "R-BTA-5672957", "name": "PP2A dephosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073919" ], "products": [ "species_10073927", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073917": { "compartment": "compartment_70101", "id": "reaction_10073917", "reactome": "R-BTA-5672951", "name": "Inactive RAFs bind YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073913" ], "products": [ "species_10073915" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073932": { "compartment": "compartment_70101", "id": "reaction_10073932", "reactome": "R-BTA-5672958", "name": "YWHAB dimer dissociates from KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073927" ], "products": [ "species_10037668", "species_10073925" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091548": { "compartment": "compartment_876", "id": "reaction_10091548", "reactome": "R-BTA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657579", "species_10074042" ], "products": [ "species_10074135" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10073921": { "compartment": "compartment_70101", "id": "reaction_10073921", "reactome": "R-BTA-5672954", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073869" ], "products": [ "species_10073919" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073904": { "compartment": "compartment_876", "id": "reaction_10073904", "reactome": "R-BTA-5672950", "name": "\"Activator\" RAF:YWHAB dimer binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10073896" ], "products": [ "species_10073898" ], "modifiers": [ [ "species_10073902", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000070853" ] }, "reaction_10073872": { "compartment": "compartment_70101", "id": "reaction_10073872", "reactome": "R-BTA-5672948", "name": "MARK3 phosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_113592" ], "products": [ "species_29370", "species_10073869" ], "modifiers": [ [ "species_10073863", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074050": { "compartment": "compartment_876", "id": "reaction_10074050", "reactome": "R-BTA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073898", "species_10074040" ], "products": [ "species_10074042" ], "modifiers": [ [ "species_10074048", "inhibitor" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10073940": { "compartment": "compartment_70101", "id": "reaction_10073940", "reactome": "R-BTA-5672960", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073938" ], "products": [ "species_10037668", "species_10073936" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073942": { "compartment": "compartment_70101", "id": "reaction_10073942", "reactome": "R-BTA-5672961", "name": "PP2A dephosphorylates inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073915" ], "products": [ "species_29372", "species_10073938" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10074184": { "compartment": "compartment_20699", "id": "reaction_10074184", "reactome": "R-BTA-5674140", "name": "PAQR3 binds inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074180", "species_10073913" ], "products": [ "species_10074182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071243", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1M5M4", "ENSBTAT00000071243" ] }, "reaction_10074221": { "compartment": "compartment_876", "id": "reaction_10074221", "reactome": "R-BTA-5675417", "name": "PEBP1 binds activated RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074213", "species_10074217" ], "products": [ "species_10074219" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000024107", "P13696", "ENSBTAT00000024107", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10074156": { "compartment": "compartment_876", "id": "reaction_10074156", "reactome": "R-BTA-5674022", "name": "BRAP autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10074144" ], "products": [ "species_10074153" ], "modifiers": [ [ "species_10074144", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074238": { "compartment": "compartment_876", "id": "reaction_10074238", "reactome": "R-BTA-5675433", "name": "PP5 dephosphorylates RAF1 S338", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074213" ], "products": [ "species_29372", "species_10074225" ], "modifiers": [ [ "species_10074235", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000010538" ] }, "reaction_10074146": { "compartment": "compartment_876", "id": "reaction_10074146", "reactome": "R-BTA-5674018", "name": "BRAP binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10074046" ], "products": [ "species_10074144" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074148": { "compartment": "compartment_70101", "id": "reaction_10074148", "reactome": "R-BTA-5674019", "name": "BRAP binds KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_10074046" ], "products": [ "species_10074048" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074231": { "compartment": "compartment_876", "id": "reaction_10074231", "reactome": "R-BTA-5675431", "name": "PP2A dephosphorylates RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074225" ], "products": [ "species_10074229", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10091534": { "compartment": "compartment_876", "id": "reaction_10091534", "reactome": "R-BTA-9649736", "name": "RAS intrinsic GTPase activity hydrolyzes GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728" ], "products": [ "species_10040312" ], "modifiers": [ [ "species_10039728", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091580": { "compartment": "compartment_876", "id": "reaction_10091580", "reactome": "R-BTA-9658253", "name": "RAS:GTP binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10039728" ], "products": [ "species_10091578" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10074137": { "compartment": "compartment_876", "id": "reaction_10074137", "reactome": "R-BTA-5672978", "name": "RAF phosphorylates MAP2K dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074123" ], "products": [ "species_10074114", "species_29370" ], "modifiers": [ [ "species_10074123", "catalyst" ], [ "species_10074125", "inhibitor" ], [ "species_10074135", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091576": { "compartment": "compartment_876", "id": "reaction_10091576", "reactome": "R-BTA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074118", "species_9657577" ], "products": [ "species_10091574" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074129": { "compartment": "compartment_876", "id": "reaction_10074129", "reactome": "R-BTA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_113592" ], "products": [ "species_10074118", "species_29370" ], "modifiers": [ [ "species_10074114", "catalyst" ], [ "species_10074127", "inhibitor" ], [ "species_10074121", "inhibitor" ], [ "species_10074125", "inhibitor" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091568": { "compartment": "compartment_876", "id": "reaction_10091568", "reactome": "R-BTA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657567", "species_10074123" ], "products": [ "species_10074125" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074176": { "compartment": "compartment_74700", "id": "reaction_10074176", "reactome": "R-BTA-5674130", "name": "MAP2Ks and MAPKs are phosphorylated at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074172" ], "products": [ "species_29370", "species_10074174" ], "modifiers": [], "additional_components": [ "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833" ] }, "reaction_10074195": { "compartment": "compartment_20699", "id": "reaction_10074195", "reactome": "R-BTA-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074190" ], "products": [ "species_29370", "species_10074192" ], "modifiers": [ [ "species_10074190", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984" ] }, "reaction_10091570": { "compartment": "compartment_876", "id": "reaction_10091570", "reactome": "R-BTA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657570" ], "products": [ "species_10074127" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091572": { "compartment": "compartment_876", "id": "reaction_10091572", "reactome": "R-BTA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657574" ], "products": [ "species_10074121" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091595": { "compartment": "compartment_876", "id": "reaction_10091595", "reactome": "R-BTA-9660557", "name": "RAS:GTP binds RAL GDS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091591", "species_10091589" ], "products": [ "species_10091593" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10091529": { "compartment": "compartment_876", "id": "reaction_10091529", "reactome": "R-BTA-9649735", "name": "Intrinsic nucleotide exchange on RAS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10075256": { "compartment": "compartment_7660", "id": "reaction_10075256", "reactome": "R-BTA-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075220" ], "products": [ "species_10075236", "species_10075202" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075260": { "compartment": "compartment_7660", "id": "reaction_10075260", "reactome": "R-BTA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075208" ], "products": [ "species_10075258" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000012303" ] }, "reaction_10075262": { "compartment": "compartment_70101", "id": "reaction_10075262", "reactome": "R-BTA-5687126", "name": "p-S215 FOXO3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075234" ], "products": [ "species_10075226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10075251": { "compartment": "compartment_70101", "id": "reaction_10075251", "reactome": "R-BTA-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075241" ], "products": [ "species_10075249" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075218": { "compartment": "compartment_7660", "id": "reaction_10075218", "reactome": "R-BTA-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066851", "species_10075214" ], "products": [ "species_10075216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075253": { "compartment": "compartment_7660", "id": "reaction_10075253", "reactome": "R-BTA-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075249" ], "products": [ "species_10075241" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "ENSBTAT00000017629" ] }, "reaction_10075223": { "compartment": "compartment_7660", "id": "reaction_10075223", "reactome": "R-BTA-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075216" ], "products": [ "species_113582", "species_10075220" ], "modifiers": [ [ "species_10075216", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075916": { "compartment": "compartment_70101", "id": "reaction_10075916", "reactome": "R-BTA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075904" ], "products": [ "species_29370", "species_10075913" ], "modifiers": [ [ "species_10075904", "catalyst" ] ], "additional_components": [ "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303", "F1MH23", "ENSBTAT00000012303", "Q3MI00", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10076193": { "compartment": "compartment_7660", "id": "reaction_10076193", "reactome": "R-BTA-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076189", "species_10076185" ], "products": [ "species_10076191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075652", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10075906": { "compartment": "compartment_70101", "id": "reaction_10075906", "reactome": "R-BTA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075236", "species_10067944" ], "products": [ "species_10075904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075205": { "compartment": "compartment_70101", "id": "reaction_10075205", "reactome": "R-BTA-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075194" ], "products": [ "species_10075202", "species_29370" ], "modifiers": [ [ "species_10047654", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10076229": { "compartment": "compartment_7660", "id": "reaction_10076229", "reactome": "R-BTA-5692779", "name": "p-S182 MAPKAPK5 phosphorylates FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10042661" ], "products": [ "species_113582", "species_10076226" ], "modifiers": [ [ "species_10066865", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127", "ENSBTAT00000012303" ] }, "reaction_10075239": { "compartment": "compartment_70101", "id": "reaction_10075239", "reactome": "R-BTA-5687101", "name": "p-T182 MAPKAPK5 phosphorylates FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075232" ], "products": [ "species_10075234", "species_29370" ], "modifiers": [ [ "species_10075236", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "ENSBTAT00000012303" ] }, "reaction_10076198": { "compartment": "compartment_7660", "id": "reaction_10076198", "reactome": "R-BTA-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076191" ], "products": [ "species_113550", "species_10076195" ], "modifiers": [ [ "species_10076191", "catalyst" ] ], "additional_components": [ "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652", "A0A3Q1MTC5", "ENSBTAT00000075652", "G5E577", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10039690": { "compartment": "compartment_74700", "id": "reaction_10039690", "reactome": "R-BTA-170964", "name": "FRS2 binds to active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039686", "species_10039684" ], "products": [ "species_10039688" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090954": { "compartment": "compartment_74700", "id": "reaction_10090954", "reactome": "R-BTA-9610163", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090951", "species_113592" ], "products": [ "species_10090933", "species_29370" ], "modifiers": [ [ "species_10090951", "catalyst" ] ], "additional_components": [ "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039711": { "compartment": "compartment_74700", "id": "reaction_10039711", "reactome": "R-BTA-170978", "name": "p-FRS2:CRKL binds C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039703", "species_10039707" ], "products": [ "species_10039709" ], "modifiers": [], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039697": { "compartment": "compartment_74700", "id": "reaction_10039697", "reactome": "R-BTA-170977", "name": "FRS2 is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039688" ], "products": [ "species_29370", "species_10039694" ], "modifiers": [ [ "species_10039688", "catalyst" ] ], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090944": { "compartment": "compartment_74700", "id": "reaction_10090944", "reactome": "R-BTA-9610153", "name": "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090935", "species_113592" ], "products": [ "species_29370", "species_10090937" ], "modifiers": [ [ "species_10090935", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10090949": { "compartment": "compartment_70101", "id": "reaction_10090949", "reactome": "R-BTA-9610156", "name": "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090937" ], "products": [ "species_10090946", "species_29370" ], "modifiers": [ [ "species_10090937", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039592": { "compartment": "compartment_876", "id": "reaction_10039592", "reactome": "R-BTA-169904", "name": "C3G stimulates nucleotide exchange on Rap1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039587" ], "products": [ "species_10039589", "species_29420" ], "modifiers": [ [ "species_10039579", "catalyst" ] ], "additional_components": [ "P62833", "ENSBTAT00000068678", "species_29420", "P62833", "ENSBTAT00000068678", "species_29438", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039581": { "compartment": "compartment_984", "id": "reaction_10039581", "reactome": "R-BTA-169895", "name": "Crk's SH3 domain engages C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039579" ], "products": [ "species_10039579" ], "modifiers": [], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039601": { "compartment": "compartment_876", "id": "reaction_10039601", "reactome": "R-BTA-169905", "name": "ARMS is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039598" ], "products": [ "species_29370", "species_10039579" ], "modifiers": [ [ "species_10039598", "catalyst" ] ], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10074879": { "compartment": "compartment_70101", "id": "reaction_10074879", "reactome": "R-BTA-5685366", "name": "GRB2-1:SOS1 binds p-Y-SHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073958", "species_10035491" ], "products": [ "species_10073960" ], "modifiers": [], "additional_components": [ "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112" ] }, "reaction_10039736": { "compartment": "compartment_876", "id": "reaction_10039736", "reactome": "R-BTA-170986", "name": "Ral-GDS binds to Ras-GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039732", "species_10039728" ], "products": [ "species_10039734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1M6Z6", "ENSBTAT00000087412" ] }, "reaction_10040570": { "compartment": "compartment_70101", "id": "reaction_10040570", "reactome": "R-BTA-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040546", "species_113592" ], "products": [ "species_10040551", "species_29370" ], "modifiers": [ [ "species_10040567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084476", "ENSBTAT00000084476", "species_29926", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10090994": { "compartment": "compartment_7660", "id": "reaction_10090994", "reactome": "R-BTA-9613213", "name": "NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090982", "species_10090978", "species_10090990" ], "products": [ "species_10090992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008295", "ENSBTAT00000019612", "G3N0C9", "ENSBTAT00000064240", "G3N0C9", "ENSBTAT00000064240", "F1N3F6", "ENSBTAT00000019612", "Q1RMU0", "ENSBTAT00000008295" ] }, "reaction_10041851": { "compartment": "compartment_947587", "id": "reaction_10041851", "reactome": "R-BTA-198266", "name": "PI3K produces PIP3 and other phosphatidyl inositides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10041848", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10041869": { "compartment": "compartment_947587", "id": "reaction_10041869", "reactome": "R-BTA-198315", "name": "Active IRS recruits PI3K to the plasma membrane and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10041865" ], "products": [ "species_10041867" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10041917": { "compartment": "compartment_7660", "id": "reaction_10041917", "reactome": "R-BTA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041913" ], "products": [ "species_10041915" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001347", "ENSBTAT00000001347" ] }, "reaction_10040489": { "compartment": "compartment_17963", "id": "reaction_10040489", "reactome": "R-BTA-187020", "name": "Part of pro-beta-NGF is processed to mature beta-NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040476" ], "products": [ "species_10040480" ], "modifiers": [ [ "species_10040486", "catalyst" ] ], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "species_74016", "A0A3Q1MCD7", "ENSBTAT00000077745" ] }, "reaction_10040495": { "compartment": "compartment_984", "id": "reaction_10040495", "reactome": "R-BTA-187035", "name": "Pro-beta-NGF and mature beta-NGF are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040480", "species_10040476" ], "products": [ "species_10039264", "species_10040493" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10090722": { "compartment": "compartment_876", "id": "reaction_10090722", "reactome": "R-BTA-9603419", "name": "Activated NTRK3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090663", "species_10090411" ], "products": [ "species_10090720" ], "modifiers": [], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090727": { "compartment": "compartment_876", "id": "reaction_10090727", "reactome": "R-BTA-9603420", "name": "Activated NTRK3 promotes SRC autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090720" ], "products": [ "species_10090724", "species_29370" ], "modifiers": [ [ "species_10090720", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090666": { "compartment": "compartment_876", "id": "reaction_10090666", "reactome": "R-BTA-9034714", "name": "NTRK3 dimers trans-autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090654" ], "products": [ "species_10090663", "species_29370" ], "modifiers": [ [ "species_10090654", "catalyst" ] ], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090675": { "compartment": "compartment_876", "id": "reaction_10090675", "reactome": "R-BTA-9034855", "name": "Activated PCLG1 dissociates from NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090673" ], "products": [ "species_10090663", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000023383" ] }, "reaction_10073244": { "compartment": "compartment_70101", "id": "reaction_10073244", "reactome": "R-BTA-5654730", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065269" ], "products": [ "species_10073210" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073215": { "compartment": "compartment_70101", "id": "reaction_10073215", "reactome": "R-BTA-5654679", "name": "CBL ubiquitinates FRS2 and FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073210" ], "products": [ "species_10073212" ], "modifiers": [ [ "species_10073210", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057337": { "compartment": "compartment_70101", "id": "reaction_10057337", "reactome": "R-BTA-1295632", "name": "PPA2A dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057334" ], "products": [ "species_10057300", "species_29372" ], "modifiers": [ [ "species_10057334", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057323": { "compartment": "compartment_70101", "id": "reaction_10057323", "reactome": "R-BTA-1295613", "name": "SPRY2 binds GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057316", "species_10035485" ], "products": [ "species_10057321" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10053082": { "compartment": "compartment_70101", "id": "reaction_10053082", "reactome": "R-BTA-934604", "name": "Phosphorylated SPRY2 is ubiquitinated by CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053077", "species_10033408" ], "products": [ "species_10053079" ], "modifiers": [ [ "species_10053077", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057327": { "compartment": "compartment_70101", "id": "reaction_10057327", "reactome": "R-BTA-1295621", "name": "CBL dissociates from ubiquitinated p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053079" ], "products": [ "species_10040359", "species_10057325" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10057329": { "compartment": "compartment_70101", "id": "reaction_10057329", "reactome": "R-BTA-1295622", "name": "SPRY2 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10057316" ], "products": [ "species_10053062", "species_10053077" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057314": { "compartment": "compartment_70101", "id": "reaction_10057314", "reactome": "R-BTA-1295604", "name": "B-RAF dissociates from S111/S120 p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057312" ], "products": [ "species_10057310", "species_10057306" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000086962", "ENSBTAT00000002324" ] }, "reaction_10059156": { "compartment": "compartment_70101", "id": "reaction_10059156", "reactome": "R-BTA-1549564", "name": "PPTN11 dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057321" ], "products": [ "species_10057316", "species_10035485" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "ENSBTAT00000002653" ] }, "reaction_10057302": { "compartment": "compartment_70101", "id": "reaction_10057302", "reactome": "R-BTA-1295599", "name": "SPRY2 translocates to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057300" ], "products": [ "species_10053066" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057318": { "compartment": "compartment_70101", "id": "reaction_10057318", "reactome": "R-BTA-1295609", "name": "SRC phosphorylates SPRY2 on Y55 and Y227", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10053066" ], "products": [ "species_10057316", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ], [ "species_10053072", "inhibitor" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000011767", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10040761": { "compartment": "compartment_984", "id": "reaction_10040761", "reactome": "R-BTA-190263", "name": "FGFR3b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040755", "species_10036461", "species_190915" ], "products": [ "species_10040759" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040779": { "compartment": "compartment_876", "id": "reaction_10040779", "reactome": "R-BTA-190385", "name": "Autocatalytic phosphorylation of FGFR3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040759", "species_113592" ], "products": [ "species_29370", "species_10036473" ], "modifiers": [ [ "species_10040759", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10083933": { "compartment": "compartment_17963", "id": "reaction_10083933", "reactome": "R-BTA-8851619", "name": "GALNT3 transfers GalNAc to FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10083928" ], "products": [ "species_205687", "species_10083930" ], "modifiers": [ [ "species_10052428", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940", "ENSBTAT00000018541" ] }, "reaction_10083935": { "compartment": "compartment_17963", "id": "reaction_10083935", "reactome": "R-BTA-8851632", "name": "GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083930" ], "products": [ "species_10036373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940" ] }, "reaction_10040782": { "compartment": "compartment_876", "id": "reaction_10040782", "reactome": "R-BTA-190388", "name": "Autocatalytic phosphorylation of FGFR3c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040751" ], "products": [ "species_10036485", "species_29370" ], "modifiers": [ [ "species_10040751", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040753": { "compartment": "compartment_984", "id": "reaction_10040753", "reactome": "R-BTA-190261", "name": "FGFR3c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040747", "species_10036475", "species_190915" ], "products": [ "species_10040751" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10073240": { "compartment": "compartment_70101", "id": "reaction_10073240", "reactome": "R-BTA-5654717", "name": "FGFR4-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065247", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073192": { "compartment": "compartment_70101", "id": "reaction_10073192", "reactome": "R-BTA-5654669", "name": "Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073188", "species_10035515" ], "products": [ "species_10073190" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073237": { "compartment": "compartment_70101", "id": "reaction_10073237", "reactome": "R-BTA-5654714", "name": "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10073190", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073177": { "compartment": "compartment_876", "id": "reaction_10073177", "reactome": "R-BTA-5654658", "name": "Activated FGFR4:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10073168" ], "products": [ "species_10073170" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073166": { "compartment": "compartment_876", "id": "reaction_10073166", "reactome": "R-BTA-5654653", "name": "Activated FGFR4 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073161" ], "products": [ "species_29370", "species_10073163" ], "modifiers": [ [ "species_10073161", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073182": { "compartment": "compartment_70101", "id": "reaction_10073182", "reactome": "R-BTA-5654663", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073179", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073184": { "compartment": "compartment_70101", "id": "reaction_10073184", "reactome": "R-BTA-5654664", "name": "Activated FGFR4:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073168" ], "products": [ "species_10073179" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073028": { "compartment": "compartment_876", "id": "reaction_10073028", "reactome": "R-BTA-5654418", "name": "Activated FGFR4 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073023" ], "products": [ "species_29370", "species_10065243" ], "modifiers": [ [ "species_10073023", "catalyst" ], [ "species_10073026", "inhibitor" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073031": { "compartment": "compartment_70101", "id": "reaction_10073031", "reactome": "R-BTA-5654422", "name": "Activated FGFR4 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10065241" ], "products": [ "species_10073023" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073175": { "compartment": "compartment_876", "id": "reaction_10073175", "reactome": "R-BTA-5654655", "name": "Activated FGFR4 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073170", "species_113592" ], "products": [ "species_10073172", "species_29370" ], "modifiers": [ [ "species_10073170", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087367": { "compartment": "compartment_70101", "id": "reaction_10087367", "reactome": "R-BTA-8941613", "name": "Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073172", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10072939": { "compartment": "compartment_876", "id": "reaction_10072939", "reactome": "R-BTA-5654169", "name": "p-4Y-PLCG1 dissociates from activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072924" ], "products": [ "species_10043237", "species_10065241" ], "modifiers": [], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072927": { "compartment": "compartment_70101", "id": "reaction_10072927", "reactome": "R-BTA-5654151", "name": "Activated FGFR4 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072922" ], "products": [ "species_29370", "species_10072924" ], "modifiers": [ [ "species_10072922", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10072933": { "compartment": "compartment_876", "id": "reaction_10072933", "reactome": "R-BTA-5654163", "name": "Activated FGFR4 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10061098", "species_10065241" ], "products": [ "species_10072922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10073246": { "compartment": "compartment_70101", "id": "reaction_10073246", "reactome": "R-BTA-5654734", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10073186" ], "products": [ "species_10073217" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073222": { "compartment": "compartment_70101", "id": "reaction_10073222", "reactome": "R-BTA-5654684", "name": "CBL ubiquitinates FRS2 and FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073217" ], "products": [ "species_10073219" ], "modifiers": [ [ "species_10073217", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040776": { "compartment": "compartment_876", "id": "reaction_10040776", "reactome": "R-BTA-190326", "name": "Autocatalytic phosphorylation of FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040767" ], "products": [ "species_10036502", "species_29370" ], "modifiers": [ [ "species_10040767", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10040769": { "compartment": "compartment_984", "id": "reaction_10040769", "reactome": "R-BTA-190265", "name": "FGFR4 binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036500", "species_10040763", "species_190915" ], "products": [ "species_10040767" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10057704": { "compartment": "compartment_70101", "id": "reaction_10057704", "reactome": "R-BTA-1307955", "name": "FGFR4 binds HS:KLB:FGF19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036498", "species_10036506", "species_10040763", "species_190915" ], "products": [ "species_10057702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022973", "ENSBTAT00000019297", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10057707": { "compartment": "compartment_876", "id": "reaction_10057707", "reactome": "R-BTA-1307963", "name": "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057702", "species_113592" ], "products": [ "species_29370", "species_10036508" ], "modifiers": [ [ "species_10057702", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10040720": { "compartment": "compartment_876", "id": "reaction_10040720", "reactome": "R-BTA-190258", "name": "FGFR2c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036438", "species_10040706", "species_190915" ], "products": [ "species_10040718" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000072473", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040788": { "compartment": "compartment_876", "id": "reaction_10040788", "reactome": "R-BTA-190413", "name": "Autocatalytic phosphorylation of FGFR2c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040718" ], "products": [ "species_29370", "species_10036459" ], "modifiers": [ [ "species_10040718", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040744": { "compartment": "compartment_876", "id": "reaction_10040744", "reactome": "R-BTA-190260", "name": "FGFR2b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036405", "species_10040722", "species_190915" ], "products": [ "species_10040734" ], "modifiers": [ [ "species_190915", "catalyst" ], [ "species_10040742", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000072473", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10040785": { "compartment": "compartment_876", "id": "reaction_10040785", "reactome": "R-BTA-190408", "name": "Autocatalytic phosphorylation of FGFR2b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040734" ], "products": [ "species_29370", "species_10036432" ], "modifiers": [ [ "species_10040734", "catalyst" ] ], "additional_components": [ "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10073328": { "compartment": "compartment_984", "id": "reaction_10073328", "reactome": "R-BTA-5656070", "name": "FGFBPs bind FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040740", "species_10040736" ], "products": [ "species_10040742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044642", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10072909": { "compartment": "compartment_70101", "id": "reaction_10072909", "reactome": "R-BTA-5654147", "name": "Activated FGFR2 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072904" ], "products": [ "species_29370", "species_10072906" ], "modifiers": [ [ "species_10072904", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072929": { "compartment": "compartment_876", "id": "reaction_10072929", "reactome": "R-BTA-5654157", "name": "p-4Y-PLCG1 dissociates from activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072906" ], "products": [ "species_10065255", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383" ] }, "reaction_10072931": { "compartment": "compartment_876", "id": "reaction_10072931", "reactome": "R-BTA-5654159", "name": "Activated FGFR2 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_179838", "species_10061098" ], "products": [ "species_10072904" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073001": { "compartment": "compartment_876", "id": "reaction_10073001", "reactome": "R-BTA-5654406", "name": "Activated FGFR2:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072988" ], "products": [ "species_10072990" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073004": { "compartment": "compartment_70101", "id": "reaction_10073004", "reactome": "R-BTA-5654407", "name": "Activated FGFR2 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072997", "species_113592" ], "products": [ "species_29370", "species_10072988" ], "modifiers": [ [ "species_10072997", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072993": { "compartment": "compartment_70101", "id": "reaction_10072993", "reactome": "R-BTA-5654402", "name": "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072990", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072999": { "compartment": "compartment_70101", "id": "reaction_10072999", "reactome": "R-BTA-5654404", "name": "Activated FGFR2 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072995" ], "products": [ "species_10072997" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073129": { "compartment": "compartment_876", "id": "reaction_10073129", "reactome": "R-BTA-5654608", "name": "Activated FGFR2:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065257" ], "products": [ "species_10073124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087370": { "compartment": "compartment_70101", "id": "reaction_10087370", "reactome": "R-BTA-8941618", "name": "Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065259", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073133": { "compartment": "compartment_70101", "id": "reaction_10073133", "reactome": "R-BTA-5654615", "name": "Activated FGFR2:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065257" ], "products": [ "species_10073131" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072976": { "compartment": "compartment_876", "id": "reaction_10072976", "reactome": "R-BTA-5654397", "name": "Activated FGFR2 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072961" ], "products": [ "species_29370", "species_10065257" ], "modifiers": [ [ "species_10072961", "catalyst" ], [ "species_10072974", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073136": { "compartment": "compartment_70101", "id": "reaction_10073136", "reactome": "R-BTA-5654618", "name": "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073131", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072979": { "compartment": "compartment_70101", "id": "reaction_10072979", "reactome": "R-BTA-5654399", "name": "Activated FGFR2 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072959" ], "products": [ "species_10072961" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073127": { "compartment": "compartment_876", "id": "reaction_10073127", "reactome": "R-BTA-5654607", "name": "Activated FGFR2 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073124", "species_113592" ], "products": [ "species_29370", "species_10065259" ], "modifiers": [ [ "species_10073124", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073231": { "compartment": "compartment_70101", "id": "reaction_10073231", "reactome": "R-BTA-5654697", "name": "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065263", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073208": { "compartment": "compartment_70101", "id": "reaction_10073208", "reactome": "R-BTA-5654677", "name": "CBL ubiquitinates FRS2 and FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073203", "species_10033408" ], "products": [ "species_10073205" ], "modifiers": [ [ "species_10073203", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073242": { "compartment": "compartment_70101", "id": "reaction_10073242", "reactome": "R-BTA-5654729", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065259" ], "products": [ "species_10073203" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073071": { "compartment": "compartment_876", "id": "reaction_10073071", "reactome": "R-BTA-5654510", "name": "FGFRL1 binds SPRED1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073053", "species_10073067" ], "products": [ "species_10073069" ], "modifiers": [], "additional_components": [ "F1MQI5", "ENSBTAT00000039444", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "F1MQI5", "ENSBTAT00000039444" ] }, "reaction_10073077": { "compartment": "compartment_876", "id": "reaction_10073077", "reactome": "R-BTA-5654511", "name": "FGFRL1 dimer binds FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073073", "species_10073053", "species_190915" ], "products": [ "species_10073075" ], "modifiers": [], "additional_components": [ "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MQI5", "ENSBTAT00000039444", "species_190915", "F1MQI5", "ENSBTAT00000039444", "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073199": { "compartment": "compartment_70101", "id": "reaction_10073199", "reactome": "R-BTA-5654672", "name": "CBL ubiquitinates FRS2 and FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073194" ], "products": [ "species_10073196" ], "modifiers": [ [ "species_10073194", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073201": { "compartment": "compartment_70101", "id": "reaction_10073201", "reactome": "R-BTA-5654673", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065249" ], "products": [ "species_10073194" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040794": { "compartment": "compartment_876", "id": "reaction_10040794", "reactome": "R-BTA-190429", "name": "Autocatalytic phosphorylation of FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040702" ], "products": [ "species_29370", "species_10036379" ], "modifiers": [ [ "species_10040702", "catalyst" ] ], "additional_components": [ "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040704": { "compartment": "compartment_984", "id": "reaction_10040704", "reactome": "R-BTA-190256", "name": "FGFR1c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036375", "species_10040698", "species_190915" ], "products": [ "species_10040702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "ENSBTAT00000083788", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040696": { "compartment": "compartment_984", "id": "reaction_10040696", "reactome": "R-BTA-190245", "name": "FGFR1b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040690", "species_190915", "species_10036328" ], "products": [ "species_10040694" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040791": { "compartment": "compartment_876", "id": "reaction_10040791", "reactome": "R-BTA-190427", "name": "Autocatalytic phosphorylation of FGFR1b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040694", "species_113592" ], "products": [ "species_29370", "species_10036344" ], "modifiers": [ [ "species_10040694", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040860": { "compartment": "compartment_876", "id": "reaction_10040860", "reactome": "R-BTA-191062", "name": "Autocatalytic phosphorylation of Klotho-bound FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040771", "species_113592" ], "products": [ "species_29370", "species_10036399" ], "modifiers": [ [ "species_10040771", "catalyst" ] ], "additional_components": [ "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040773": { "compartment": "compartment_984", "id": "reaction_10040773", "reactome": "R-BTA-190268", "name": "FGFR1c binds to Klotho-bound FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036397", "species_10040698", "species_190915" ], "products": [ "species_10040771" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10073097": { "compartment": "compartment_876", "id": "reaction_10073097", "reactome": "R-BTA-5654578", "name": "Activated FGFR1 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073094", "species_113592" ], "products": [ "species_10072950", "species_29370" ], "modifiers": [ [ "species_10073094", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073113": { "compartment": "compartment_876", "id": "reaction_10073113", "reactome": "R-BTA-5654587", "name": "Activated FGFR1:p-FRS phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073104" ], "products": [ "species_10073110", "species_29370" ], "modifiers": [ [ "species_10073104", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073083": { "compartment": "compartment_70101", "id": "reaction_10073083", "reactome": "R-BTA-5654569", "name": "Activated FGFR1 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10072959" ], "products": [ "species_10073079" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072957": { "compartment": "compartment_70101", "id": "reaction_10072957", "reactome": "R-BTA-5654392", "name": "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072954", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10087373": { "compartment": "compartment_70101", "id": "reaction_10087373", "reactome": "R-BTA-8941623", "name": "Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073110", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073090": { "compartment": "compartment_876", "id": "reaction_10073090", "reactome": "R-BTA-5654575", "name": "Activated FGFR1 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073079", "species_113592" ], "products": [ "species_29370", "species_10065235" ], "modifiers": [ [ "species_10073079", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073106": { "compartment": "compartment_876", "id": "reaction_10073106", "reactome": "R-BTA-5654584", "name": "Activated FGFR1:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10072952" ], "products": [ "species_10073104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073108": { "compartment": "compartment_70101", "id": "reaction_10073108", "reactome": "R-BTA-5654586", "name": "Activated FGFR1:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072952" ], "products": [ "species_10072954" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073225": { "compartment": "compartment_70101", "id": "reaction_10073225", "reactome": "R-BTA-5654690", "name": "FGFR1-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065239", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073115": { "compartment": "compartment_70101", "id": "reaction_10073115", "reactome": "R-BTA-5654596", "name": "Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065251", "species_10035515" ], "products": [ "species_10065253" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073228": { "compartment": "compartment_70101", "id": "reaction_10073228", "reactome": "R-BTA-5654692", "name": "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065253", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073087": { "compartment": "compartment_70101", "id": "reaction_10073087", "reactome": "R-BTA-5654573", "name": "Activated FGFR1 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065233" ], "products": [ "species_10073085" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073119": { "compartment": "compartment_876", "id": "reaction_10073119", "reactome": "R-BTA-5654597", "name": "Activated FGFR1:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073099" ], "products": [ "species_10073117" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073102": { "compartment": "compartment_70101", "id": "reaction_10073102", "reactome": "R-BTA-5654582", "name": "Activated FGFR1 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073085" ], "products": [ "species_29370", "species_10073099" ], "modifiers": [ [ "species_10073085", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073122": { "compartment": "compartment_70101", "id": "reaction_10073122", "reactome": "R-BTA-5654600", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073117", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073326": { "compartment": "compartment_876", "id": "reaction_10073326", "reactome": "R-BTA-5656064", "name": "Activated FGFR1 binds FLRT1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10073322" ], "products": [ "species_10073324" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072937": { "compartment": "compartment_876", "id": "reaction_10072937", "reactome": "R-BTA-5654167", "name": "Activated FGFR1 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065233", "species_10061098" ], "products": [ "species_10072915" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072920": { "compartment": "compartment_70101", "id": "reaction_10072920", "reactome": "R-BTA-5654149", "name": "Activated FGFR1 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072915", "species_113592" ], "products": [ "species_10072917", "species_29370" ], "modifiers": [ [ "species_10072915", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072935": { "compartment": "compartment_876", "id": "reaction_10072935", "reactome": "R-BTA-5654165", "name": "p-4Y-PLCG1 dissociates from activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072917" ], "products": [ "species_10043237", "species_10065233" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10091689": { "compartment": "compartment_876", "id": "reaction_10091689", "reactome": "R-BTA-9674095", "name": "PDGFRs bind type II TKI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9674079", "species_10040472" ], "products": [ "species_10091687" ], "modifiers": [], "additional_components": [ "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976", "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976" ] }, "reaction_10046666": { "compartment": "compartment_984", "id": "reaction_10046666", "reactome": "R-BTA-382057", "name": "Release of novel PDGFs as latent factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046658" ], "products": [ "species_10046664" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10046677": { "compartment": "compartment_984", "id": "reaction_10046677", "reactome": "R-BTA-382061", "name": "Extracellular processing of novel PDGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046664" ], "products": [ "species_10046672", "species_10046670" ], "modifiers": [ [ "species_10046674", "catalyst" ] ], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10046660": { "compartment": "compartment_20699", "id": "reaction_10046660", "reactome": "R-BTA-382053", "name": "Translocation of PDGF from ER to Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046654" ], "products": [ "species_10046658" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10057850": { "compartment": "compartment_876", "id": "reaction_10057850", "reactome": "R-BTA-1433454", "name": "Phosphorylation of GAB2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043813", "species_113592" ], "products": [ "species_10057847", "species_29370" ], "modifiers": [ [ "species_10043813", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1M864", "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10057854": { "compartment": "compartment_876", "id": "reaction_10057854", "reactome": "R-BTA-1433456", "name": "Recruitment of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057840", "species_10046556" ], "products": [ "species_10057852" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057872": { "compartment": "compartment_876", "id": "reaction_10057872", "reactome": "R-BTA-1433514", "name": "Synthesis of PIP3 from PIP2 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057869", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10058480": { "compartment": "compartment_876", "id": "reaction_10058480", "reactome": "R-BTA-1470012", "name": "Disassociation and translocation of STATs to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058476" ], "products": [ "species_10057840", "species_10052345" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10091667": { "compartment": "compartment_876", "id": "reaction_10091667", "reactome": "R-BTA-9669854", "name": "KIT binds type II TKIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9669722" ], "products": [ "species_10091665" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057845": { "compartment": "compartment_876", "id": "reaction_10057845", "reactome": "R-BTA-1433428", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043807", "species_10035485" ], "products": [ "species_10043809" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10043832": { "compartment": "compartment_876", "id": "reaction_10043832", "reactome": "R-BTA-205244", "name": "Recruitment of CBL to KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10043828" ], "products": [ "species_10043830" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057867": { "compartment": "compartment_876", "id": "reaction_10057867", "reactome": "R-BTA-1433506", "name": "Phosphorylation of APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057864" ], "products": [ "species_10043826", "species_29370" ], "modifiers": [ [ "species_10057864", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781" ] }, "reaction_10058474": { "compartment": "compartment_876", "id": "reaction_10058474", "reactome": "R-BTA-1470009", "name": "Phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057852" ], "products": [ "species_10058471", "species_29370" ], "modifiers": [ [ "species_10057852", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10058478": { "compartment": "compartment_876", "id": "reaction_10058478", "reactome": "R-BTA-1470010", "name": "Dimerization of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058471" ], "products": [ "species_10058476" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10057857": { "compartment": "compartment_876", "id": "reaction_10057857", "reactome": "R-BTA-1433471", "name": "Activation of RAS by p-KIT bound SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10043817", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10043815": { "compartment": "compartment_876", "id": "reaction_10043815", "reactome": "R-BTA-205234", "name": "Indirect recruitment of GAB2 to p-KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10043809" ], "products": [ "species_10043813" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10091751": { "compartment": "compartment_876", "id": "reaction_10091751", "reactome": "R-BTA-9681375", "name": "KIT binds ripretinib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9674322" ], "products": [ "species_10091749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057862": { "compartment": "compartment_876", "id": "reaction_10057862", "reactome": "R-BTA-1433488", "name": "Phosphorylation of SHP2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057859", "species_113592" ], "products": [ "species_29370", "species_10043807" ], "modifiers": [ [ "species_10057859", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10041657": { "compartment": "compartment_876", "id": "reaction_10041657", "reactome": "R-BTA-195408", "name": "NRP-1 forms a ternary complex with VEGF165 and VEGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041653", "species_10041457" ], "products": [ "species_10041655" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026471", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "E1BMX5", "ENSBTAT00000026471" ] }, "reaction_10041649": { "compartment": "compartment_984", "id": "reaction_10041649", "reactome": "R-BTA-195378", "name": "Homodimerization of VEGF proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041441" ], "products": [ "species_10041443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019613", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10070651": { "compartment": "compartment_876", "id": "reaction_10070651", "reactome": "R-BTA-5218820", "name": "Src kinases phosphorylate VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070647", "species_113592" ], "products": [ "species_29370", "species_10070649" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070589": { "compartment": "compartment_876", "id": "reaction_10070589", "reactome": "R-BTA-5218640", "name": "SRC-1 phosphorylates p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070580", "species_113592" ], "products": [ "species_29370", "species_10070586" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070657": { "compartment": "compartment_876", "id": "reaction_10070657", "reactome": "R-BTA-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070655" ], "products": [ "species_29370", "species_10070605" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "ENSBTAT00000039221" ] }, "reaction_10070628": { "compartment": "compartment_70101", "id": "reaction_10070628", "reactome": "R-BTA-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070612", "species_112275", "species_74016" ], "products": [ "species_10070626" ], "modifiers": [], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_74016", "species_112275", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10070615": { "compartment": "compartment_70101", "id": "reaction_10070615", "reactome": "R-BTA-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070605" ], "products": [ "species_10070612", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10069535": { "compartment": "compartment_876", "id": "reaction_10069535", "reactome": "R-BTA-4420206", "name": "Phosphorylation of SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069530" ], "products": [ "species_29370", "species_10069532" ], "modifiers": [ [ "species_10069530", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071504": { "compartment": "compartment_876", "id": "reaction_10071504", "reactome": "R-BTA-5357429", "name": "AXL autophosphorylates on Y772 and Y814", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071501" ], "products": [ "species_29370", "species_10070638" ], "modifiers": [ [ "species_10071501", "catalyst" ] ], "additional_components": [ "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071506": { "compartment": "compartment_876", "id": "reaction_10071506", "reactome": "R-BTA-5357432", "name": "AXL binds SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069532", "species_10071499" ], "products": [ "species_10071501" ], "modifiers": [], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10070645": { "compartment": "compartment_876", "id": "reaction_10070645", "reactome": "R-BTA-5218819", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10070642", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10071508": { "compartment": "compartment_876", "id": "reaction_10071508", "reactome": "R-BTA-5357479", "name": "p-AXL binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10070638" ], "products": [ "species_10070640" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10070676": { "compartment": "compartment_876", "id": "reaction_10070676", "reactome": "R-BTA-5218847", "name": "PAK2 binds NCK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047604", "species_10070672" ], "products": [ "species_10070674" ], "modifiers": [], "additional_components": [ "A0A3Q1M0G8", "ENSBTAT00000082239", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10070624": { "compartment": "compartment_876", "id": "reaction_10070624", "reactome": "R-BTA-5218806", "name": "FYN autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070619" ], "products": [ "species_29370", "species_10070621" ], "modifiers": [ [ "species_10070619", "catalyst" ] ], "additional_components": [ "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10070594": { "compartment": "compartment_70101", "id": "reaction_10070594", "reactome": "R-BTA-5218642", "name": "PTK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070591" ], "products": [ "species_10070578", "species_29370" ], "modifiers": [ [ "species_10070591", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070596": { "compartment": "compartment_876", "id": "reaction_10070596", "reactome": "R-BTA-5218645", "name": "SRC-1 binds p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070578", "species_10040957" ], "products": [ "species_10070580" ], "modifiers": [], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10056781": { "compartment": "compartment_876", "id": "reaction_10056781", "reactome": "R-BTA-1236398", "name": "ERBB4 binds NRGs or EGF-like ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056771", "species_10056765" ], "products": [ "species_10056779" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057151": { "compartment": "compartment_984", "id": "reaction_10057151", "reactome": "R-BTA-1250220", "name": "Homodimerization of ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056779" ], "products": [ "species_10057149" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057166": { "compartment": "compartment_70101", "id": "reaction_10057166", "reactome": "R-BTA-1250315", "name": "Trans-autophosphorylation of ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057149" ], "products": [ "species_29370", "species_10057163" ], "modifiers": [ [ "species_10057149", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057184": { "compartment": "compartment_876", "id": "reaction_10057184", "reactome": "R-BTA-1250370", "name": "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057181", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "P32871", "ENSBTAT00000072391" ] }, "reaction_10090971": { "compartment": "compartment_876", "id": "reaction_10090971", "reactome": "R-BTA-9612219", "name": "ERBB4s80 binds to SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10057211" ], "products": [ "species_10057250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057262": { "compartment": "compartment_70101", "id": "reaction_10057262", "reactome": "R-BTA-1253282", "name": "ERBB4 ubiquitination by WWP1/ITCH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10057257" ], "products": [ "species_10057259" ], "modifiers": [ [ "species_10057257", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057264": { "compartment": "compartment_876", "id": "reaction_10057264", "reactome": "R-BTA-1253300", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055126", "species_10057255" ], "products": [ "species_10057257" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057272": { "compartment": "compartment_70101", "id": "reaction_10057272", "reactome": "R-BTA-1253343", "name": "WWOX binds ERBB4s80", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10057211" ], "products": [ "species_10057270" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10057298": { "compartment": "compartment_70101", "id": "reaction_10057298", "reactome": "R-BTA-1254376", "name": "Translocation of cytosolic ERBB4s80 to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057296" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057236": { "compartment": "compartment_70101", "id": "reaction_10057236", "reactome": "R-BTA-1251997", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057201" ], "products": [ "species_10057211" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10057252": { "compartment": "compartment_70101", "id": "reaction_10057252", "reactome": "R-BTA-1252013", "name": "Translocation of ERBB4s80 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057246" ], "modifiers": [ [ "species_10057250", "inhibitor" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057284": { "compartment": "compartment_70101", "id": "reaction_10057284", "reactome": "R-BTA-1254248", "name": "Translocation of ERBB4s80:YAP1 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057278" ], "products": [ "species_10057282" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10057286": { "compartment": "compartment_70101", "id": "reaction_10057286", "reactome": "R-BTA-1254251", "name": "ERBB4s80 binds YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276", "species_10057211" ], "products": [ "species_10057278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10084080": { "compartment": "compartment_984", "id": "reaction_10084080", "reactome": "R-BTA-8852552", "name": "MST1R autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084065" ], "products": [ "species_29370", "species_10084077" ], "modifiers": [ [ "species_10084065", "catalyst" ] ], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10084067": { "compartment": "compartment_984", "id": "reaction_10084067", "reactome": "R-BTA-8852522", "name": "MST1 dimer:MST1R dimer binds MST1R dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080868", "species_10080866" ], "products": [ "species_10084065" ], "modifiers": [], "additional_components": [ "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10080870": { "compartment": "compartment_876", "id": "reaction_10080870", "reactome": "R-BTA-6800315", "name": "MST1 binds MST1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080866", "species_10080858" ], "products": [ "species_10080868" ], "modifiers": [], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028" ] }, "reaction_10091705": { "compartment": "compartment_459", "id": "reaction_10091705", "reactome": "R-BTA-9674531", "name": "AAMP binds EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091695", "species_10040201" ], "products": [ "species_10091703" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005126", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3SZK1", "ENSBTAT00000005126" ] }, "reaction_10040393": { "compartment": "compartment_70101", "id": "reaction_10040393", "reactome": "R-BTA-182993", "name": "Ubiquitination of stimulated EGFR (CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040366" ], "products": [ "species_10040388" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040458": { "compartment": "compartment_70101", "id": "reaction_10040458", "reactome": "R-BTA-183058", "name": "Phosphorylation of CBL (EGFR:GRB2:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040455", "species_113592" ], "products": [ "species_29370", "species_10040395" ], "modifiers": [ [ "species_10040455", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040460": { "compartment": "compartment_70101", "id": "reaction_10040460", "reactome": "R-BTA-183067", "name": "Localization of CBL:GRB2 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10040449" ], "products": [ "species_10040455" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040447": { "compartment": "compartment_70101", "id": "reaction_10040447", "reactome": "R-BTA-183051", "name": "CBL ubiquitinates Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040440" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040440", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10040462": { "compartment": "compartment_70101", "id": "reaction_10040462", "reactome": "R-BTA-183089", "name": "CBL binds and ubiquitinates phosphorylated Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040382", "species_10040366" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040369": { "compartment": "compartment_70101", "id": "reaction_10040369", "reactome": "R-BTA-182969", "name": "Phosphorylation of CBL (EGFR:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040361" ], "products": [ "species_29370", "species_10040366" ], "modifiers": [ [ "species_10040361", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040432": { "compartment": "compartment_70101", "id": "reaction_10040432", "reactome": "R-BTA-183036", "name": "Ubiquitination of stimulated EGFR (CBL:GRB2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040395" ], "products": [ "species_10040425" ], "modifiers": [ [ "species_10040395", "catalyst" ], [ "species_10040430", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000061187" ] }, "reaction_10040451": { "compartment": "compartment_70101", "id": "reaction_10040451", "reactome": "R-BTA-183052", "name": "CBL binds to GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10035485" ], "products": [ "species_10040449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040386": { "compartment": "compartment_876", "id": "reaction_10040386", "reactome": "R-BTA-182988", "name": "Sprouty lures CBL away from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040374", "species_10040359" ], "products": [ "species_10040384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002324", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040453": { "compartment": "compartment_876", "id": "reaction_10040453", "reactome": "R-BTA-183055", "name": "Binding of CBL to EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10040243" ], "products": [ "species_10040361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040421": { "compartment": "compartment_70101", "id": "reaction_10040421", "reactome": "R-BTA-182994", "name": "Assembly of EGFR complex in clathrin-coated vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040417", "species_10040395" ], "products": [ "species_10040419" ], "modifiers": [], "additional_components": [ "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040331": { "compartment": "compartment_70101", "id": "reaction_10040331", "reactome": "R-BTA-177945", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040301", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040303": { "compartment": "compartment_70101", "id": "reaction_10040303", "reactome": "R-BTA-177936", "name": "GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10040283" ], "products": [ "species_10040301" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040286": { "compartment": "compartment_70101", "id": "reaction_10040286", "reactome": "R-BTA-177933", "name": "SHC1 phosphorylation by phosphorylated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040256", "species_113592" ], "products": [ "species_29370", "species_10040283" ], "modifiers": [ [ "species_10040256", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040258": { "compartment": "compartment_70101", "id": "reaction_10040258", "reactome": "R-BTA-177925", "name": "SHC1 binds to the phosphorylated EGF receptor:ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035544" ], "products": [ "species_10040256" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040289": { "compartment": "compartment_70101", "id": "reaction_10040289", "reactome": "R-BTA-177934", "name": "EGFR autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040227", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10036616": { "compartment": "compartment_70101", "id": "reaction_10036616", "reactome": "R-BTA-109813", "name": "GRB2-1 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10035485" ], "products": [ "species_10035491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040317": { "compartment": "compartment_70101", "id": "reaction_10040317", "reactome": "R-BTA-177938", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040314", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040326": { "compartment": "compartment_70101", "id": "reaction_10040326", "reactome": "R-BTA-177943", "name": "GRB2:SOS1 complex binds to EGF:EGFR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035491" ], "products": [ "species_10040314" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040323": { "compartment": "compartment_984", "id": "reaction_10040323", "reactome": "R-BTA-177942", "name": "EGFR binds EGF ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040223", "species_10040201" ], "products": [ "species_10040225" ], "modifiers": [ [ "species_10040321", "inhibitor" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000030750" ] }, "reaction_10040229": { "compartment": "compartment_876", "id": "reaction_10040229", "reactome": "R-BTA-177922", "name": "EGFR dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040225" ], "products": [ "species_10040227" ], "modifiers": [], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10044472": { "compartment": "compartment_876", "id": "reaction_10044472", "reactome": "R-BTA-212713", "name": "Active PLC-gamma1 dissociates from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044467" ], "products": [ "species_10043237", "species_10040243" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044465": { "compartment": "compartment_876", "id": "reaction_10044465", "reactome": "R-BTA-212706", "name": "Phospholipase C-gamma1 binds to the activated EGF receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043197" ], "products": [ "species_10044463" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044470": { "compartment": "compartment_70101", "id": "reaction_10044470", "reactome": "R-BTA-212710", "name": "EGFR activates PLC-gamma1 by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044463" ], "products": [ "species_29370", "species_10044467" ], "modifiers": [ [ "species_10044463", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040310": { "compartment": "compartment_70101", "id": "reaction_10040310", "reactome": "R-BTA-177937", "name": "Phosphorylation of EGFR by SRC kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000011767" ] }, "reaction_10035536": { "compartment": "compartment_70101", "id": "reaction_10035536", "reactome": "R-BTA-74746", "name": "GRB2-1:SOS1 binds p-Y427-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035532" ], "products": [ "species_10035534" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10075065": { "compartment": "compartment_70101", "id": "reaction_10075065", "reactome": "R-BTA-5686074", "name": "GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036626" ], "products": [ "species_10036624", "species_10035532" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "ENSBTAT00000075224" ] }, "reaction_10075097": { "compartment": "compartment_70101", "id": "reaction_10075097", "reactome": "R-BTA-5686315", "name": "GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036628" ], "products": [ "species_10036624", "species_10035503" ], "modifiers": [], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10083487": { "compartment": "compartment_70101", "id": "reaction_10083487", "reactome": "R-BTA-8848110", "name": "SOCS3 binds activated PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051731", "species_10083480" ], "products": [ "species_10083485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011106", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q9BEG9", "ENSBTAT00000011106" ] }, "reaction_10083565": { "compartment": "compartment_70101", "id": "reaction_10083565", "reactome": "R-BTA-8848436", "name": "PTK6 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083556", "species_113592" ], "products": [ "species_29370", "species_10083562", "species_10083480" ], "modifiers": [ [ "species_10083556", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083558": { "compartment": "compartment_70101", "id": "reaction_10083558", "reactome": "R-BTA-8848414", "name": "Activated PTK6 binds CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083554", "species_10083480" ], "products": [ "species_10083556" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083646": { "compartment": "compartment_70101", "id": "reaction_10083646", "reactome": "R-BTA-8848864", "name": "PTK6 binds ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083642", "species_10083480" ], "products": [ "species_10083644" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083632": { "compartment": "compartment_70101", "id": "reaction_10083632", "reactome": "R-BTA-8848818", "name": "PTK6 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_113592" ], "products": [ "species_29370", "species_10052267" ], "modifiers": [ [ "species_10083480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000061122" ] }, "reaction_10083652": { "compartment": "compartment_70101", "id": "reaction_10083652", "reactome": "R-BTA-8848873", "name": "PTK6 phosphorylates ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083644" ], "products": [ "species_29370", "species_10083649", "species_10083480" ], "modifiers": [ [ "species_10083644", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568", "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083638": { "compartment": "compartment_70101", "id": "reaction_10083638", "reactome": "R-BTA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10052267" ], "products": [ "species_10083635" ], "modifiers": [ [ "species_10052267", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000072559" ] }, "reaction_10083690": { "compartment": "compartment_70101", "id": "reaction_10083690", "reactome": "R-BTA-8849068", "name": "PTK6 phosphorylates ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083682", "species_113592" ], "products": [ "species_10083687", "species_29370", "species_10083480" ], "modifiers": [ [ "species_10083682", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083581": { "compartment": "compartment_70101", "id": "reaction_10083581", "reactome": "R-BTA-8848596", "name": "PTK6 binds PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070667", "species_10083480" ], "products": [ "species_10083579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083629": { "compartment": "compartment_70101", "id": "reaction_10083629", "reactome": "R-BTA-8848726", "name": "PTK6 phosphorylates BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083620", "species_113592" ], "products": [ "species_29370", "species_10083626", "species_10083480" ], "modifiers": [ [ "species_10083620", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322", "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083695": { "compartment": "compartment_70101", "id": "reaction_10083695", "reactome": "R-BTA-8849082", "name": "ARHGAP35 stimulates RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083692" ], "products": [ "species_10083687", "species_29372", "species_10037313" ], "modifiers": [ [ "species_10083692", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083697": { "compartment": "compartment_70101", "id": "reaction_10083697", "reactome": "R-BTA-8849085", "name": "ARHGAP35 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083687", "species_10037315" ], "products": [ "species_10083692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083588": { "compartment": "compartment_70101", "id": "reaction_10083588", "reactome": "R-BTA-8848606", "name": "PTK6 phosphorylates PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083579" ], "products": [ "species_29370", "species_10083585", "species_10083480" ], "modifiers": [ [ "species_10083579", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101", "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083684": { "compartment": "compartment_70101", "id": "reaction_10083684", "reactome": "R-BTA-8849055", "name": "PTK6 binds ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083680", "species_10083480" ], "products": [ "species_10083682" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083622": { "compartment": "compartment_70101", "id": "reaction_10083622", "reactome": "R-BTA-8848713", "name": "PTK6 binds BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083618", "species_10083480" ], "products": [ "species_10083620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083707": { "compartment": "compartment_70101", "id": "reaction_10083707", "reactome": "R-BTA-8849102", "name": "SRMS phosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083480" ], "products": [ "species_10083700", "species_29370" ], "modifiers": [ [ "species_10083704", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000002574" ] }, "reaction_10083726": { "compartment": "compartment_70101", "id": "reaction_10083726", "reactome": "R-BTA-8849428", "name": "PTPN1 binds PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055952", "species_10083480" ], "products": [ "species_10083724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10083729": { "compartment": "compartment_70101", "id": "reaction_10083729", "reactome": "R-BTA-8849435", "name": "PTPN1 dephosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083724" ], "products": [ "species_29372", "species_10055952", "species_10083473" ], "modifiers": [ [ "species_10083724", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678", "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090428": { "compartment": "compartment_876", "id": "reaction_10090428", "reactome": "R-BTA-9021627", "name": "EPOR-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10090425", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10089841": { "compartment": "compartment_876", "id": "reaction_10089841", "reactome": "R-BTA-9012657", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047493", "species_10089837" ], "products": [ "species_10089839" ], "modifiers": [], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10090501": { "compartment": "compartment_876", "id": "reaction_10090501", "reactome": "R-BTA-9027272", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090415" ], "products": [ "species_29370", "species_10089837" ], "modifiers": [ [ "species_10090415", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10073851": { "compartment": "compartment_17938", "id": "reaction_10073851", "reactome": "R-BTA-5672828", "name": "mTORC1 phosphorylates AKT1S1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039143", "species_113592" ], "products": [ "species_29370", "species_10073848" ], "modifiers": [ [ "species_10039143", "catalyst" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046572": { "compartment": "compartment_70101", "id": "reaction_10046572", "reactome": "R-BTA-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042890", "species_76577" ], "products": [ "species_10046570" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10046588": { "compartment": "compartment_70101", "id": "reaction_10046588", "reactome": "R-BTA-380979", "name": "RHEB in mTORC1:RHEB:GTP hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_29372", "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046583": { "compartment": "compartment_70101", "id": "reaction_10046583", "reactome": "R-BTA-380949", "name": "AMPK is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10042890" ], "products": [ "species_29372", "species_10042880" ], "modifiers": [ [ "species_10046580", "catalyst" ] ], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MBG5", "ENSBTAT00000000017", "F1MQV7", "ENSBTAT00000024965", "ENSBTAT00000024128" ] }, "reaction_10049894": { "compartment": "compartment_876", "id": "reaction_10049894", "reactome": "R-BTA-447074", "name": "AMPK phosphorylates Raptor in the mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_113592" ], "products": [ "species_29370", "species_10039178" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10088493": { "compartment": "compartment_70101", "id": "reaction_10088493", "reactome": "R-BTA-8952716", "name": "SLC38A9 binds Ragulator:Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039075", "species_10039119" ], "products": [ "species_10039121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10073853": { "compartment": "compartment_17938", "id": "reaction_10073853", "reactome": "R-BTA-5672843", "name": "AKT1S1 (PRAS40) binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_10039145" ], "products": [ "species_10039147" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000007575", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10088496": { "compartment": "compartment_70101", "id": "reaction_10088496", "reactome": "R-BTA-8952726", "name": "SLC38A9 transports L-Arg from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428011" ], "products": [ "species_29468" ], "modifiers": [ [ "species_10039121", "catalyst" ] ], "additional_components": [ "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039059": { "compartment": "compartment_17938", "id": "reaction_10039059", "reactome": "R-BTA-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039055" ], "products": [ "species_29420", "species_10039057" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438" ] }, "reaction_10039209": { "compartment": "compartment_70101", "id": "reaction_10039209", "reactome": "R-BTA-165758", "name": "Phosphorylation and inactivation of eEF2K by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039204", "species_113592" ], "products": [ "species_10039207", "species_29370" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023487", "ENSBTAT00000023487", "ENSBTAT00000022415" ] }, "reaction_10039160": { "compartment": "compartment_70101", "id": "reaction_10039160", "reactome": "R-BTA-165708", "name": "Dissociation of phosphorylated 4EBP1 from eIF4E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039133" ], "products": [ "species_10034357", "species_10039131" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10091741": { "compartment": "compartment_70101", "id": "reaction_10091741", "reactome": "R-BTA-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10039151" ], "products": [ "species_10039153" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10039180": { "compartment": "compartment_17938", "id": "reaction_10039180", "reactome": "R-BTA-165718", "name": "mTORC1 phosphorylation of RPS6KB1 (S6K)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039164" ], "products": [ "species_29370", "species_10039168" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039178", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022415", "ENSBTAT00000022415", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10039200": { "compartment": "compartment_70101", "id": "reaction_10039200", "reactome": "R-BTA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034529" ], "products": [ "species_29370", "species_10039197" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1N412", "ENSBTAT00000019214", "ENSBTAT00000022415" ] }, "reaction_10039155": { "compartment": "compartment_17938", "id": "reaction_10039155", "reactome": "R-BTA-165692", "name": "Phosphorylation of 4E-BP1 by activated mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034363" ], "products": [ "species_29370", "species_10039133" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039147", "inhibitor" ] ], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072900": { "compartment": "compartment_70101", "id": "reaction_10072900", "reactome": "R-BTA-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039101", "species_10039115" ], "products": [ "species_10039117" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438" ] }, "reaction_10073844": { "compartment": "compartment_17938", "id": "reaction_10073844", "reactome": "R-BTA-5672824", "name": "Phosphorylated AKT1S1:mTORC1 binds YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039141", "species_10037666" ], "products": [ "species_10039143" ], "modifiers": [], "additional_components": [ "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039127": { "compartment": "compartment_70101", "id": "reaction_10039127", "reactome": "R-BTA-165680", "name": "Formation of active mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039123", "species_10039057" ], "products": [ "species_10039125" ], "modifiers": [], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072902": { "compartment": "compartment_70101", "id": "reaction_10072902", "reactome": "R-BTA-5653974", "name": "Ragulator binds Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039095", "species_10039117" ], "products": [ "species_10039119" ], "modifiers": [], "additional_components": [ "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10046602": { "compartment": "compartment_12045", "id": "reaction_10046602", "reactome": "R-BTA-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046594", "species_113592" ], "products": [ "species_10046599", "species_29370" ], "modifiers": [ [ "species_10046594", "catalyst" ] ], "additional_components": [ "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10046604": { "compartment": "compartment_12045", "id": "reaction_10046604", "reactome": "R-BTA-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046592" ], "products": [ "species_10046594" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10085865": { "compartment": "compartment_7660", "id": "reaction_10085865", "reactome": "R-BTA-8874849", "name": "CREBRF binds CREB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085861", "species_10085857" ], "products": [ "species_10085863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065187", "ENSBTAT00000015193", "Q8SQ19", "ENSBTAT00000015193", "E1BPS0", "ENSBTAT00000065187" ] }, "reaction_10060285": { "compartment": "compartment_161320", "id": "reaction_10060285", "reactome": "R-BTA-1630304", "name": "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2105007", "species_1605715" ], "products": [ "species_2104997", "species_1606845" ], "modifiers": [ [ "species_10060282", "catalyst" ] ], "additional_components": [ "F1MU84", "ENSBTAT00000006001" ] }, "reaction_10091293": { "compartment": "compartment_161320", "id": "reaction_10091293", "reactome": "R-BTA-9638078", "name": "HEXB cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060293": { "compartment": "compartment_161320", "id": "reaction_10060293", "reactome": "R-BTA-1638032", "name": "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2104995" ], "products": [ "species_1606845", "species_2105012" ], "modifiers": [ [ "species_10060290", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023218" ] }, "reaction_10060295": { "compartment": "compartment_161320", "id": "reaction_10060295", "reactome": "R-BTA-1638053", "name": "HEXA cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10063510": { "compartment": "compartment_984", "id": "reaction_10063510", "reactome": "R-BTA-2046239", "name": "Extracellular KSPG translocates to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063483" ], "products": [ "species_10060854" ], "modifiers": [], "additional_components": [ "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279" ] }, "reaction_10038201": { "compartment": "compartment_984", "id": "reaction_10038201", "reactome": "R-BTA-158311", "name": "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038157" ], "products": [ "species_10038198", "species_10038196", "species_10038188" ], "modifiers": [ [ "species_10038157", "catalyst" ] ], "additional_components": [ "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10091546": { "compartment": "compartment_17957", "id": "reaction_10091546", "reactome": "R-BTA-9650473", "name": "SERPING1 is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091544" ], "products": [ "species_10038209" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "ENSBTAT00000021638" ] }, "reaction_10038205": { "compartment": "compartment_984", "id": "reaction_10038205", "reactome": "R-BTA-158354", "name": "kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038143", "species_10038203" ], "products": [ "species_10038145" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10090718": { "compartment": "compartment_984", "id": "reaction_10090718", "reactome": "R-BTA-9603302", "name": "Factor IIa inhibitors (peptide) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603327", "species_10037577" ], "products": [ "species_10038217" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038129": { "compartment": "compartment_984", "id": "reaction_10038129", "reactome": "R-BTA-158145", "name": "factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037535", "species_10038121" ], "products": [ "species_10038127" ], "modifiers": [], "additional_components": [ "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945" ] }, "reaction_10091600": { "compartment": "compartment_17957", "id": "reaction_10091600", "reactome": "R-BTA-9661625", "name": "FVIII is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076686" ], "products": [ "species_10038115" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10091671": { "compartment": "compartment_984", "id": "reaction_10091671", "reactome": "R-BTA-9670014", "name": "Factor VIIIa dissociates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10091669", "species_10071930" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726", "ENSBTAT00000036726" ] }, "reaction_10038166": { "compartment": "compartment_876", "id": "reaction_10038166", "reactome": "R-BTA-158251", "name": "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038147" ], "products": [ "species_10038157" ], "modifiers": [ [ "species_10038163", "catalyst" ] ], "additional_components": [ "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "F1MAU4", "ENSBTAT00000047906" ] }, "reaction_10090185": { "compartment": "compartment_984", "id": "reaction_10090185", "reactome": "R-BTA-9015379", "name": "Factor IIa inhibitors (compounds) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603311", "species_10037577" ], "products": [ "species_10038215" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10071946": { "compartment": "compartment_984", "id": "reaction_10071946", "reactome": "R-BTA-5607043", "name": "factor VIIIa associates with cell membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10038174" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10038221": { "compartment": "compartment_984", "id": "reaction_10038221", "reactome": "R-BTA-158419", "name": "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038127" ], "products": [ "species_10038182" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ], [ "species_10038219", "inhibitor" ] ], "additional_components": [ "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038149": { "compartment": "compartment_876", "id": "reaction_10038149", "reactome": "R-BTA-158218", "name": "prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038133", "species_10038145" ], "products": [ "species_10038147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503" ] }, "reaction_10038213": { "compartment": "compartment_984", "id": "reaction_10038213", "reactome": "R-BTA-158399", "name": "kallikrein binds SERPING1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038209", "species_10038188" ], "products": [ "species_10038211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "E1BMJ0", "ENSBTAT00000021638" ] }, "reaction_10035301": { "compartment": "compartment_7660", "id": "reaction_10035301", "reactome": "R-BTA-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035297", "species_10035293" ], "products": [ "species_10035299" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006308", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "E1B883", "ENSBTAT00000006308" ] }, "reaction_10035254": { "compartment": "compartment_350", "id": "reaction_10035254", "reactome": "R-BTA-73718", "name": "UBF-1 Binds rDNA Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73682", "species_10035051" ], "products": [ "species_10035053" ], "modifiers": [ [ "species_10035231", "inhibitor" ], [ "species_10035252", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034806", "F1MCZ7", "ENSBTAT00000034806", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10034224": { "compartment": "compartment_70101", "id": "reaction_10034224", "reactome": "R-BTA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10034221", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P37980", "ENSBTAT00000010311" ] }, "reaction_10050169": { "compartment": "compartment_5460", "id": "reaction_10050169", "reactome": "R-BTA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10050166", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "A0A3Q1LXA8", "ENSBTAT00000086411" ] }, "reaction_10038107": { "compartment": "compartment_70101", "id": "reaction_10038107", "reactome": "R-BTA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10038103" ], "products": [ "species_10038105" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005581", "Q3SYU2", "ENSBTAT00000005581", "species_29438" ] }, "reaction_10038082": { "compartment": "compartment_70101", "id": "reaction_10038082", "reactome": "R-BTA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034837" ], "products": [ "species_10038080", "species_10034641" ], "modifiers": [], "additional_components": [ "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000035330" ] }, "reaction_10034365": { "compartment": "compartment_70101", "id": "reaction_10034365", "reactome": "R-BTA-72622", "name": "Release of eIF4E from the inactive eIF4E:4E-BP complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034363" ], "products": [ "species_10034357", "species_10034361" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10034855": { "compartment": "compartment_70101", "id": "reaction_10034855", "reactome": "R-BTA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034839", "species_10034853" ], "products": [ "species_10034853", "species_10034837", "species_10034609" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000023455", "ENSBTAT00000023455", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484" ] }, "reaction_10034905": { "compartment": "compartment_70101", "id": "reaction_10034905", "reactome": "R-BTA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034901", "species_10034385" ], "products": [ "species_10034903" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455" ] }, "reaction_10034383": { "compartment": "compartment_70101", "id": "reaction_10034383", "reactome": "R-BTA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10034379" ], "products": [ "species_10034381" ], "modifiers": [], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10034387": { "compartment": "compartment_70101", "id": "reaction_10034387", "reactome": "R-BTA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72393", "species_10034381" ], "products": [ "species_10034385" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10060894": { "compartment": "compartment_70101", "id": "reaction_10060894", "reactome": "R-BTA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060890", "species_10060888" ], "products": [ "species_10060892" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912" ] }, "reaction_10048380": { "compartment": "compartment_17957", "id": "reaction_10048380", "reactome": "R-BTA-421416", "name": "Proglucagon translocates from the ER Lumen to secretory granules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048376" ], "products": [ "species_10048378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972" ] }, "reaction_10046723": { "compartment": "compartment_984", "id": "reaction_10046723", "reactome": "R-BTA-383313", "name": "Glucagon-like Peptide 1 is secreted from intestinal L cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046709" ], "products": [ "species_10046626" ], "modifiers": [ [ "species_10046721", "catalyst" ], [ "species_10046044", "catalyst" ], [ "species_10046717", "catalyst" ], [ "species_10046130", "catalyst" ], [ "species_70115", "catalyst" ], [ "species_372533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972", "E1B8Q3", "ENSBTAT00000026313", "A0A3Q1NGS8", "ENSBTAT00000082648", "G1K1V2", "ENSBTAT00000023234", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "G5E5H9", "ENSBTAT00000019647", "species_8848483", "CHEBI:71466", "CHEBI:28716", "species_426576", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "CHEBI:16196", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560" ] }, "reaction_10045736": { "compartment": "compartment_984", "id": "reaction_10045736", "reactome": "R-BTA-378975", "name": "Follitropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045700", "species_10041260" ], "products": [ "species_10045702" ], "modifiers": [ [ "species_10045734", "catalyst" ], [ "species_10045722", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000014462", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04837", "ENSBTAT00000014462", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07994", "ENSBTAT00000013154" ] }, "reaction_10045694": { "compartment": "compartment_984", "id": "reaction_10045694", "reactome": "R-BTA-378952", "name": "Thyrotropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043952", "species_10041260" ], "products": [ "species_10043954" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008264", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10045744": { "compartment": "compartment_984", "id": "reaction_10045744", "reactome": "R-BTA-378978", "name": "CGA and CGB3 bind to form Human chorionic gonadotropin (hCG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041260", "species_10045740" ], "products": [ "species_10045742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078886", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10045696": { "compartment": "compartment_984", "id": "reaction_10045696", "reactome": "R-BTA-378956", "name": "Luteinizing hormone is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041265", "species_10041260" ], "products": [ "species_10041267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057054", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10091056": { "compartment": "compartment_984", "id": "reaction_10091056", "reactome": "R-BTA-9619024", "name": "CES1trimer hydrolyses ACEI pro-drugs to ACEIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_9619052" ], "products": [ "species_8878776", "species_9619021" ], "modifiers": [ [ "species_10076366", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461" ] }, "reaction_10048461": { "compartment": "compartment_17957", "id": "reaction_10048461", "reactome": "R-BTA-422051", "name": "Cleavage of the signal peptide of Preproghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048434" ], "products": [ "species_10048438" ], "modifiers": [ [ "species_10048458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "P67810", "ENSBTAT00000014925", "Q2KI36", "ENSBTAT00000015866", "A0A3Q1MLX7", "ENSBTAT00000083476", "E1BEI2", "ENSBTAT00000008726" ] }, "reaction_10048429": { "compartment": "compartment_876", "id": "reaction_10048429", "reactome": "R-BTA-422048", "name": "Acyl Ghrelin and C-Ghrelin are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048421", "species_10048413" ], "products": [ "species_10048423", "species_10046085" ], "modifiers": [ [ "species_10046613", "catalyst" ], [ "species_70115", "inhibitor" ], [ "species_10038908", "inhibitor" ], [ "species_10048427", "inhibitor" ], [ "species_422024", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000014713", "ENSBTAT00000000972", "ENSBTAT00000082606" ] }, "reaction_10048465": { "compartment": "compartment_17957", "id": "reaction_10048465", "reactome": "R-BTA-422104", "name": "Ghrelin O-acyltransferase octanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_422042", "species_10048398" ], "products": [ "species_10048463" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10048407": { "compartment": "compartment_17957", "id": "reaction_10048407", "reactome": "R-BTA-422017", "name": "Ghrelin O-acyltransferase decanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048398", "species_422019" ], "products": [ "species_10048400" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10049385": { "compartment": "compartment_1462052", "id": "reaction_10049385", "reactome": "R-BTA-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049382", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001343" ] }, "reaction_10049392": { "compartment": "compartment_20699", "id": "reaction_10049392", "reactome": "R-BTA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049389", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086579" ] }, "reaction_10085101": { "compartment": "compartment_70101", "id": "reaction_10085101", "reactome": "R-BTA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29404", "species_113592" ], "products": [ "species_10085076", "species_29372", "species_29370" ], "modifiers": [ [ "species_10085098", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "G3N2U5", "ENSBTAT00000064999", "A7E2Z5", "ENSBTAT00000017043", "E1BKB4", "ENSBTAT00000069658" ] }, "reaction_10085250": { "compartment": "compartment_70101", "id": "reaction_10085250", "reactome": "R-BTA-8867370", "name": "TTLL3, TTLL8, TTLL10 polyglycylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_113592", "species_29424" ], "products": [ "species_29372", "species_10085237", "species_29370" ], "modifiers": [ [ "species_10085247", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N325", "ENSBTAT00000034047", "G3N3S4", "ENSBTAT00000065735" ] }, "reaction_10087993": { "compartment": "compartment_70101", "id": "reaction_10087993", "reactome": "R-BTA-8952044", "name": "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087978" ], "products": [ "species_10087990", "species_10087869" ], "modifiers": [ [ "species_10087978", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MXH0", "ENSBTAT00000068692", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207" ] }, "reaction_10087848": { "compartment": "compartment_70101", "id": "reaction_10087848", "reactome": "R-BTA-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075935", "species_10087835" ], "products": [ "species_111294", "species_10087845", "species_76577" ], "modifiers": [ [ "species_10087835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10087883": { "compartment": "compartment_70101", "id": "reaction_10087883", "reactome": "R-BTA-8951764", "name": "Transfer of NEDD8 to AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087871" ], "products": [ "species_10087845", "species_10087880" ], "modifiers": [ [ "species_10087871", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087885": { "compartment": "compartment_70101", "id": "reaction_10087885", "reactome": "R-BTA-8951766", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087869", "species_10087850" ], "products": [ "species_10087871" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087852": { "compartment": "compartment_70101", "id": "reaction_10087852", "reactome": "R-BTA-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087845", "species_113592", "species_10075935" ], "products": [ "species_111294", "species_10087850", "species_76577" ], "modifiers": [], "additional_components": [ "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10088734": { "compartment": "compartment_7660", "id": "reaction_10088734", "reactome": "R-BTA-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088730", "species_10088728" ], "products": [ "species_10088732" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10087825": { "compartment": "compartment_70101", "id": "reaction_10087825", "reactome": "R-BTA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075937" ], "products": [ "species_10075927", "species_10075935" ], "modifiers": [], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000079440", "ENSBTAT00000028591" ] }, "reaction_10088688": { "compartment": "compartment_70101", "id": "reaction_10088688", "reactome": "R-BTA-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10088684" ], "products": [ "species_10088686" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10088787": { "compartment": "compartment_70101", "id": "reaction_10088787", "reactome": "R-BTA-8956026", "name": "CUL9:RBX1 ubiquitinates BIRC5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10088761" ], "products": [ "species_10088764" ], "modifiers": [ [ "species_10088774", "catalyst" ], [ "species_10088785", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018046", "ENSBTAT00000018046", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591", "F6R7X9", "ENSBTAT00000024194", "E1BK00", "ENSBTAT00000061262", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591" ] }, "reaction_10088807": { "compartment": "compartment_70101", "id": "reaction_10088807", "reactome": "R-BTA-8956040", "name": "COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088802" ], "products": [ "species_10088804", "species_10075935" ], "modifiers": [ [ "species_10084815", "catalyst" ] ], "additional_components": [ "A0A3Q1MTL8", "ENSBTAT00000087337", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MXH0", "ENSBTAT00000068692", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "ENSBTAT00000028591", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10075942": { "compartment": "compartment_70101", "id": "reaction_10075942", "reactome": "R-BTA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075933" ], "products": [ "species_10075939", "species_10075937" ], "modifiers": [ [ "species_10075933", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440" ] }, "reaction_10038457": { "compartment": "compartment_70101", "id": "reaction_10038457", "reactome": "R-BTA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10038454", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017653" ] }, "reaction_10038464": { "compartment": "compartment_12045", "id": "reaction_10038464", "reactome": "R-BTA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10038461", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012921" ] }, "reaction_10052665": { "compartment": "compartment_17963", "id": "reaction_10052665", "reactome": "R-BTA-914012", "name": "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052629" ], "products": [ "species_10052652", "species_205687" ], "modifiers": [ [ "species_10052662", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "Q7YQE1", "ENSBTAT00000079217", "A0A3Q1MUB2", "ENSBTAT00000076540" ] }, "reaction_10052521": { "compartment": "compartment_17963", "id": "reaction_10052521", "reactome": "R-BTA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052519", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382" ] }, "reaction_10077688": { "compartment": "compartment_20699", "id": "reaction_10077688", "reactome": "R-BTA-6786012", "name": "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10052652" ], "products": [ "species_742343", "species_10077681" ], "modifiers": [ [ "species_10077685", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "ENSBTAT00000022569" ] }, "reaction_10052461": { "compartment": "compartment_20699", "id": "reaction_10052461", "reactome": "R-BTA-913675", "name": "GALNTs transfer GalNAc from UDP-GalNAc to mucins to form Tn antigens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052377" ], "products": [ "species_10052400", "species_205687" ], "modifiers": [ [ "species_10052458", "catalyst" ] ], "additional_components": [ "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1MQ00", "ENSBTAT00000071740", "A0A3Q1M986", "ENSBTAT00000078875", "E1BPR6", "ENSBTAT00000061536", "E1BDW8", "ENSBTAT00000028329", "E1BBP1", "ENSBTAT00000018541", "E1BHN6", "ENSBTAT00000010847", "A6QLX6", "ENSBTAT00000077005", "E1BKQ9", "ENSBTAT00000023104", "Q07537", "ENSBTAT00000081582", "A0A3Q1LM69", "ENSBTAT00000087139", "F6QA59", "ENSBTAT00000023106" ] }, "reaction_10052716": { "compartment": "compartment_20699", "id": "reaction_10052716", "reactome": "R-BTA-914018", "name": "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052569" ], "products": [ "species_205687", "species_10052713" ], "modifiers": [ [ "species_10052656", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000079217" ] }, "reaction_10052606": { "compartment": "compartment_20699", "id": "reaction_10052606", "reactome": "R-BTA-914010", "name": "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_205687", "species_10052569" ], "modifiers": [ [ "species_10052603", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1MPZ8", "ENSBTAT00000078680", "A7YY64", "ENSBTAT00000024024", "F1MGN7", "ENSBTAT00000063600", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494", "Q0VC83", "ENSBTAT00000021344" ] }, "reaction_10054575": { "compartment": "compartment_20699", "id": "reaction_10054575", "reactome": "R-BTA-977228", "name": "Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000083430" ] }, "reaction_10054766": { "compartment": "compartment_20699", "id": "reaction_10054766", "reactome": "R-BTA-981809", "name": "ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10054701" ], "products": [ "species_10054759", "species_727810" ], "modifiers": [ [ "species_10054763", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "ENSBTAT00000063122" ] }, "reaction_10054722": { "compartment": "compartment_20699", "id": "reaction_10054722", "reactome": "R-BTA-981497", "name": "ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054701" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10054773": { "compartment": "compartment_17963", "id": "reaction_10054773", "reactome": "R-BTA-981814", "name": "GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054770", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000078008" ] }, "reaction_10054550": { "compartment": "compartment_17963", "id": "reaction_10054550", "reactome": "R-BTA-977071", "name": "Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052400" ], "products": [ "species_10054548", "species_727810" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "ENSBTAT00000083430" ] }, "reaction_10052496": { "compartment": "compartment_17963", "id": "reaction_10052496", "reactome": "R-BTA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052494", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675" ] }, "reaction_10061538": { "compartment": "compartment_20699", "id": "reaction_10061538", "reactome": "R-BTA-1964505", "name": "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052629", "species_205687" ], "modifiers": [ [ "species_10061535", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "Q0VC84", "ENSBTAT00000068688", "Q3SX46", "ENSBTAT00000028542" ] }, "reaction_10052546": { "compartment": "compartment_17963", "id": "reaction_10052546", "reactome": "R-BTA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052544", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10052690": { "compartment": "compartment_17963", "id": "reaction_10052690", "reactome": "R-BTA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052400" ], "products": [ "species_10052688", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10076773": { "compartment": "compartment_20699", "id": "reaction_10076773", "reactome": "R-BTA-5694487", "name": "A4GNT transfers GlcNAc to core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052652" ], "products": [ "species_10076766", "species_205687" ], "modifiers": [ [ "species_10076770", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000001899" ] }, "reaction_10070145": { "compartment": "compartment_12045", "id": "reaction_10070145", "reactome": "R-BTA-5173005", "name": "B3GALTL transfers glucose to O-fucosyl-proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070064", "species_173594" ], "products": [ "species_158602", "species_10070138" ], "modifiers": [ [ "species_10070142", "catalyst" ] ], "additional_components": [ "F1MXR3", "ENSBTAT00000081541", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BK41", "ENSBTAT00000061071", "E1BK41", "ENSBTAT00000061071", "F1MXR3", "ENSBTAT00000081541", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "ENSBTAT00000047526" ] }, "reaction_10077897": { "compartment": "compartment_70101", "id": "reaction_10077897", "reactome": "R-BTA-6788855", "name": "FN3KRP phosphorylates PsiAm, RibAm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788865" ], "products": [ "species_6788858", "species_29370" ], "modifiers": [ [ "species_10077894", "catalyst" ] ], "additional_components": [ "CHEBI:87176", "CHEBI:87177", "CHEBI:87180", "CHEBI:87179", "ENSBTAT00000020456" ] }, "reaction_10077883": { "compartment": "compartment_12045", "id": "reaction_10077883", "reactome": "R-BTA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10077880", "catalyst" ] ], "additional_components": [ "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10038408": { "compartment": "compartment_13959", "id": "reaction_10038408", "reactome": "R-BTA-159757", "name": "Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038406" ], "products": [ "species_10038394" ], "modifiers": [], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10038416": { "compartment": "compartment_13959", "id": "reaction_10038416", "reactome": "R-BTA-159783", "name": "Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038412" ], "products": [ "species_10038414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009746", "ENSBTAT00000009746" ] }, "reaction_10038438": { "compartment": "compartment_13959", "id": "reaction_10038438", "reactome": "R-BTA-159843", "name": "Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038436" ], "products": [ "species_10038384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406" ] }, "reaction_10043698": { "compartment": "compartment_70101", "id": "reaction_10043698", "reactome": "R-BTA-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_204628", "species_73473" ], "products": [ "species_204635", "species_29360", "species_10043689" ], "modifiers": [ [ "species_10043695", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ6", "ENSBTAT00000008200" ] }, "reaction_10043717": { "compartment": "compartment_70101", "id": "reaction_10043717", "reactome": "R-BTA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10043708", "species_29360" ], "modifiers": [ [ "species_10043714", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q0VC53", "ENSBTAT00000006935", "species_71067" ] }, "reaction_10060109": { "compartment": "compartment_17957", "id": "reaction_10060109", "reactome": "R-BTA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194653", "species_10060079" ], "products": [ "species_1663154", "species_194697", "species_10060106" ], "modifiers": [ [ "species_10060045", "catalyst" ] ], "additional_components": [ "F1N665", "ENSBTAT00000014061", "Q148F3", "ENSBTAT00000026877", "A0A3Q1LZ44", "ENSBTAT00000081469", "A6QLZ3", "ENSBTAT00000010988", "G3N2T7", "ENSBTAT00000072310", "A0A3Q1LGQ6", "ENSBTAT00000080500", "E1BIN3", "ENSBTAT00000017050", "A5D7J7", "ENSBTAT00000050377", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LZ44", "ENSBTAT00000081469", "F1N665", "ENSBTAT00000014061", "G3N2T7", "ENSBTAT00000072310", "A6QLZ3", "ENSBTAT00000010988", "E1BIN3", "ENSBTAT00000017050", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LGQ6", "ENSBTAT00000080500", "A5D7J7", "ENSBTAT00000050377", "Q148F3", "ENSBTAT00000026877", "ENSBTAT00000055237" ] }, "reaction_10091630": { "compartment": "compartment_17963", "id": "reaction_10091630", "reactome": "R-BTA-9668023", "name": "TPST1,2 transfer SO4(2-) from PAPS to FVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091620", "species_741440" ], "products": [ "species_742343", "species_10091628" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036726", "ENSBTAT00000036726", "ENSBTAT00000000502" ] }, "reaction_10071579": { "compartment": "compartment_70101", "id": "reaction_10071579", "reactome": "R-BTA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071569", "species_71284" ], "products": [ "species_10071572", "species_71285" ], "modifiers": [ [ "species_10071576", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000025327" ] }, "reaction_10071566": { "compartment": "compartment_70101", "id": "reaction_10071566", "reactome": "R-BTA-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071559", "species_113592", "species_31633" ], "products": [ "species_111294", "species_10038103", "species_76577" ], "modifiers": [ [ "species_10071563", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000055382" ] }, "reaction_10066409": { "compartment": "compartment_7660", "id": "reaction_10066409", "reactome": "R-BTA-2993763", "name": "SENP1,2,5 proteolytically process SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066405" ], "products": [ "species_10066407" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023029", "ENSBTAT00000023029", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066380": { "compartment": "compartment_7660", "id": "reaction_10066380", "reactome": "R-BTA-2990842", "name": "SENP1,2,5 proteolytically process SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066376" ], "products": [ "species_10066378" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081472", "ENSBTAT00000081472", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066372": { "compartment": "compartment_7660", "id": "reaction_10066372", "reactome": "R-BTA-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066355" ], "products": [ "species_10051814" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10077406": { "compartment": "compartment_7660", "id": "reaction_10077406", "reactome": "R-BTA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056739", "species_10077402" ], "products": [ "species_10077404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055368", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "Q2TA10", "ENSBTAT00000055368" ] }, "reaction_10076001": { "compartment": "compartment_70101", "id": "reaction_10076001", "reactome": "R-BTA-5690870", "name": "OTUD7B,TNFAIP3 deubiquitinate TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075996" ], "products": [ "species_10052288", "species_10075998" ], "modifiers": [ [ "species_10075996", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10085345": { "compartment": "compartment_70101", "id": "reaction_10085345", "reactome": "R-BTA-8869506", "name": "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10085342" ], "products": [ "species_10039539", "species_10075998" ], "modifiers": [ [ "species_10085342", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075952": { "compartment": "compartment_70101", "id": "reaction_10075952", "reactome": "R-BTA-5690827", "name": "TNFAIP3 (A20) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10075944" ], "products": [ "species_10075949" ], "modifiers": [ [ "species_10075944", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075984": { "compartment": "compartment_70101", "id": "reaction_10075984", "reactome": "R-BTA-5690845", "name": "TNIPs bind TNFAIP3 (A20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037956", "species_10075980" ], "products": [ "species_10075982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069028", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10084931": { "compartment": "compartment_70101", "id": "reaction_10084931", "reactome": "R-BTA-8865182", "name": "OTUD7A hydrolyses K11diUb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075838" ], "products": [ "species_10033408" ], "modifiers": [ [ "species_10084928", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000009023" ] }, "reaction_10075970": { "compartment": "compartment_70101", "id": "reaction_10075970", "reactome": "R-BTA-5690843", "name": "OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075966", "species_10075962" ], "products": [ "species_10075968" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600" ] }, "reaction_10075989": { "compartment": "compartment_70101", "id": "reaction_10075989", "reactome": "R-BTA-5690856", "name": "TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075986" ], "products": [ "species_10039539", "species_10075944" ], "modifiers": [ [ "species_10075986", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10077371": { "compartment": "compartment_70101", "id": "reaction_10077371", "reactome": "R-BTA-6781899", "name": "USP13 binds SIAH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077367", "species_10054896" ], "products": [ "species_10077369" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061390", "ENSBTAT00000044404", "F1MBM6", "ENSBTAT00000044404", "E1BMF7", "ENSBTAT00000061390" ] }, "reaction_10077339": { "compartment": "compartment_70101", "id": "reaction_10077339", "reactome": "R-BTA-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077335", "species_10071514" ], "products": [ "species_10077337" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025198", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10075550": { "compartment": "compartment_7660", "id": "reaction_10075550", "reactome": "R-BTA-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075418" ], "products": [ "species_10075422", "species_10075547" ], "modifiers": [ [ "species_10075418", "catalyst" ] ], "additional_components": [ "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418", "F1N556", "ENSBTAT00000007177", "A6QLP0", "ENSBTAT00000006418", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10075902": { "compartment": "compartment_7660", "id": "reaction_10075902", "reactome": "R-BTA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075897" ], "products": [ "species_10036828", "species_10075899" ], "modifiers": [ [ "species_10075897", "catalyst" ] ], "additional_components": [ "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1MY85", "ENSBTAT00000087113" ] }, "reaction_10077393": { "compartment": "compartment_7660", "id": "reaction_10077393", "reactome": "R-BTA-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077388" ], "products": [ "species_10075488", "species_10077390" ], "modifiers": [ [ "species_10077388", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075891": { "compartment": "compartment_70101", "id": "reaction_10075891", "reactome": "R-BTA-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075886" ], "products": [ "species_10033408", "species_10075888" ], "modifiers": [ [ "species_10075886", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356" ] }, "reaction_10077363": { "compartment": "compartment_70101", "id": "reaction_10077363", "reactome": "R-BTA-6781897", "name": "USP11 deubiquitinates NFKBIA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077358" ], "products": [ "species_10077360", "species_10075884" ], "modifiers": [ [ "species_10077358", "catalyst" ] ], "additional_components": [ "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10077331": { "compartment": "compartment_7660", "id": "reaction_10077331", "reactome": "R-BTA-5696958", "name": "USP44 deubiquitinates CDC20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077326" ], "products": [ "species_10077328", "species_10075547" ], "modifiers": [ [ "species_10077326", "catalyst" ] ], "additional_components": [ "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571" ] }, "reaction_10075561": { "compartment": "compartment_7660", "id": "reaction_10075561", "reactome": "R-BTA-5689973", "name": "USP10,USP24,USP42 deubiquitinate TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075556" ], "products": [ "species_10075558", "species_10075547" ], "modifiers": [ [ "species_10075556", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967", "A0A452DHT6", "ENSBTAT00000000967", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967" ] }, "reaction_10077034": { "compartment": "compartment_70101", "id": "reaction_10077034", "reactome": "R-BTA-5696564", "name": "USP25 deubiquitinates DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077029" ], "products": [ "species_10077031", "species_10075884" ], "modifiers": [ [ "species_10077029", "catalyst" ] ], "additional_components": [ "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MMX0", "ENSBTAT00000075352", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10077292": { "compartment": "compartment_17906", "id": "reaction_10077292", "reactome": "R-BTA-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077171" ], "products": [ "species_10077189", "species_10077289" ], "modifiers": [ [ "species_10077171", "catalyst" ] ], "additional_components": [ "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733" ] }, "reaction_10077070": { "compartment": "compartment_70101", "id": "reaction_10077070", "reactome": "R-BTA-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077061" ], "products": [ "species_10075884", "species_10077067" ], "modifiers": [ [ "species_10077061", "catalyst" ] ], "additional_components": [ "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MKU1", "ENSBTAT00000061377", "E1BJZ0", "ENSBTAT00000010703", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075808": { "compartment": "compartment_7660", "id": "reaction_10075808", "reactome": "R-BTA-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075801" ], "products": [ "species_10036828", "species_10075805" ], "modifiers": [ [ "species_10075801", "catalyst" ] ], "additional_components": [ "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438" ] }, "reaction_10077379": { "compartment": "compartment_7660", "id": "reaction_10077379", "reactome": "R-BTA-6781922", "name": "USP13 binds UFD1L:SKP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077375", "species_10077373" ], "products": [ "species_10077377" ], "modifiers": [], "additional_components": [ "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000061390", "E1BMF7", "ENSBTAT00000061390", "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10077349": { "compartment": "compartment_70101", "id": "reaction_10077349", "reactome": "R-BTA-6781814", "name": "USP19 deubiquitinates RNF123", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077344" ], "products": [ "species_10077346", "species_10039539" ], "modifiers": [ [ "species_10077344", "catalyst" ] ], "additional_components": [ "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10077317": { "compartment": "compartment_7660", "id": "reaction_10077317", "reactome": "R-BTA-5696914", "name": "USP28 deubiquitinates CLSPN and MYC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077308" ], "products": [ "species_10077314", "species_10075547" ], "modifiers": [ [ "species_10077308", "catalyst" ] ], "additional_components": [ "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1LF69", "ENSBTAT00000074281", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720" ] }, "reaction_10075374": { "compartment": "compartment_7660", "id": "reaction_10075374", "reactome": "R-BTA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10075370" ], "products": [ "species_10075372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10075397": { "compartment": "compartment_70101", "id": "reaction_10075397", "reactome": "R-BTA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039539" ], "products": [ "species_10039539", "species_10039537" ], "modifiers": [ [ "species_10075394", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MF75", "ENSBTAT00000067648", "A6H799", "ENSBTAT00000007611", "A0A3Q1M4J1", "ENSBTAT00000073722", "F1ME39", "ENSBTAT00000008984" ] }, "reaction_10086303": { "compartment": "compartment_7660", "id": "reaction_10086303", "reactome": "R-BTA-8932275", "name": "METTL22 transfers 3xCH3 from 3xAdoMet to KIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086293" ], "products": [ "species_77502", "species_10086296" ], "modifiers": [ [ "species_10086300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061405", "ENSBTAT00000061405", "ENSBTAT00000084035" ] }, "reaction_10086319": { "compartment": "compartment_70101", "id": "reaction_10086319", "reactome": "R-BTA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_71285", "species_10086312" ], "modifiers": [ [ "species_10086316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000085737" ] }, "reaction_10086286": { "compartment": "compartment_70101", "id": "reaction_10086286", "reactome": "R-BTA-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_10086279", "species_71285" ], "modifiers": [ [ "species_10086283", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000065836" ] }, "reaction_10077744": { "compartment": "compartment_70101", "id": "reaction_10077744", "reactome": "R-BTA-6786205", "name": "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10037000" ], "products": [ "species_71285", "species_10077737" ], "modifiers": [ [ "species_10077741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044622", "ENSBTAT00000044622", "ENSBTAT00000046124" ] }, "reaction_10083231": { "compartment": "compartment_70101", "id": "reaction_10083231", "reactome": "R-BTA-6814418", "name": "PDCL promotes formation of G-beta:G-gamma heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037407", "species_10083225" ], "products": [ "species_10083229" ], "modifiers": [], "additional_components": [ "P63212", "ENSBTAT00000003959", "Q2HJA9", "ENSBTAT00000043370", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648" ] }, "reaction_10083808": { "compartment": "compartment_70101", "id": "reaction_10083808", "reactome": "R-BTA-8850560", "name": "G-protein alpha releases G-protein heterotrimer from PDCL ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083229", "species_10036952" ], "products": [ "species_10083806", "species_10083195" ], "modifiers": [], "additional_components": [ "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "ENSBTAT00000043370" ] }, "reaction_10077947": { "compartment": "compartment_3828046", "id": "reaction_10077947", "reactome": "R-BTA-6791016", "name": "SFTPB binds itself", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074840" ], "products": [ "species_10074859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "P15781", "ENSBTAT00000045134" ] }, "reaction_10088922": { "compartment": "compartment_12045", "id": "reaction_10088922", "reactome": "R-BTA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088918" ], "products": [ "species_10088920" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074686": { "compartment": "compartment_2133233", "id": "reaction_10074686", "reactome": "R-BTA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10074683", "catalyst" ] ], "additional_components": [ "species_429785", "species_1602402", "species_429785", "species_1602402", "ENSBTAT00000019840" ] }, "reaction_10074833": { "compartment": "compartment_80738", "id": "reaction_10074833", "reactome": "R-BTA-5684862", "name": "SFTPB,C, PC, PG translocate from lamellar body to extracellular region.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074821", "species_10074817", "species_5684869" ], "products": [ "species_5686242", "species_10074827", "species_10074825" ], "modifiers": [ [ "species_10048001", "catalyst" ], [ "species_10046205", "catalyst" ], [ "species_10074831", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_429785", "species_1602402", "species_1602402", "species_429785", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "ENSBTAT00000035930" ] }, "reaction_10091120": { "compartment": "compartment_12045", "id": "reaction_10091120", "reactome": "R-BTA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088920" ], "products": [ "species_10075101" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074707": { "compartment": "compartment_7660", "id": "reaction_10074707", "reactome": "R-BTA-5683831", "name": "CCDC59 binds TTF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074703", "species_10074699" ], "products": [ "species_10074705" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024905", "ENSBTAT00000050784", "A5PJN1", "ENSBTAT00000050784", "E1B9V4", "ENSBTAT00000024905" ] }, "reaction_10074869": { "compartment": "compartment_12045", "id": "reaction_10074869", "reactome": "R-BTA-5684868", "name": "pro-SFTPC translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074865" ], "products": [ "species_10074867" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672" ] }, "reaction_10075125": { "compartment": "compartment_876", "id": "reaction_10075125", "reactome": "R-BTA-5686359", "name": "SFTPs translocate from extracellular region to clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075103" ], "products": [ "species_10075111", "species_10075123", "species_10075117", "species_10075099", "species_10075115" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134" ] }, "reaction_10091124": { "compartment": "compartment_12045", "id": "reaction_10091124", "reactome": "R-BTA-9624789", "name": "pro-SFTPB translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091122" ], "products": [ "species_10074838" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134" ] }, "reaction_10075095": { "compartment": "compartment_876", "id": "reaction_10075095", "reactome": "R-BTA-5686304", "name": "ZDHHC2 transfers PALM from PALM-CoA to CKAP4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075088", "species_200993" ], "products": [ "species_10075070", "species_76194" ], "modifiers": [ [ "species_10075092", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015804", "ENSBTAT00000015804", "ENSBTAT00000064000" ] }, "reaction_10074857": { "compartment": "compartment_3828046", "id": "reaction_10074857", "reactome": "R-BTA-5684864", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074838", "species_5685882" ], "products": [ "species_10074844", "species_10074842", "species_10074840" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10075019": { "compartment": "compartment_12045", "id": "reaction_10075019", "reactome": "R-BTA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075015" ], "products": [ "species_10075017" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075084": { "compartment": "compartment_876", "id": "reaction_10075084", "reactome": "R-BTA-5686286", "name": "PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075072" ], "products": [ "species_10075082" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804", "F1ME65", "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075023": { "compartment": "compartment_3828046", "id": "reaction_10075023", "reactome": "R-BTA-5685902", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5685882", "species_10074867" ], "products": [ "species_10075021", "species_10074861" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672", "ENSBTAT00000016672", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10074863": { "compartment": "compartment_3828046", "id": "reaction_10074863", "reactome": "R-BTA-5684865", "name": "SFTPB dimer,C translocate from multivesicle body to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074861", "species_10074859" ], "products": [ "species_10074821", "species_10074817" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134" ] }, "reaction_10075086": { "compartment": "compartment_876", "id": "reaction_10075086", "reactome": "R-BTA-5686301", "name": "PALM-C100-CKAP4 binds SFTPAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075070", "species_10075017" ], "products": [ "species_10075072" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804" ] }, "reaction_10075105": { "compartment": "compartment_876", "id": "reaction_10075105", "reactome": "R-BTA-5686335", "name": "CSF2RA:CSF2RB binds SFTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075101", "species_10074827", "species_10075099", "species_10074825", "species_10075017" ], "products": [ "species_10075103" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579" ] }, "reaction_10081291": { "compartment": "compartment_70101", "id": "reaction_10081291", "reactome": "R-BTA-6800797", "name": "The PIDDosome activates CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081288" ], "products": [ "species_10081284", "species_10043771", "species_10043769" ], "modifiers": [ [ "species_10081288", "catalyst" ] ], "additional_components": [ "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "ENSBTAT00000071790", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081274": { "compartment": "compartment_7660", "id": "reaction_10081274", "reactome": "R-BTA-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10081269" ], "products": [ "species_113582", "species_10081272" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157", "ENSBTAT00000040104" ] }, "reaction_10081293": { "compartment": "compartment_70101", "id": "reaction_10081293", "reactome": "R-BTA-6800798", "name": "The PIDDosome binds CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043767", "species_10081284" ], "products": [ "species_10081288" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081278": { "compartment": "compartment_70101", "id": "reaction_10081278", "reactome": "R-BTA-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081272" ], "products": [ "species_10081276" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157" ] }, "reaction_10081286": { "compartment": "compartment_70101", "id": "reaction_10081286", "reactome": "R-BTA-6800794", "name": "PIDD1 associates with CRADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081282", "species_10081276" ], "products": [ "species_10081284" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071531", "ENSBTAT00000026157", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531" ] }, "reaction_10080457": { "compartment": "compartment_7660", "id": "reaction_10080457", "reactome": "R-BTA-6799097", "name": "ATM phosphorylates ZNF420", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10053725" ], "products": [ "species_113582", "species_10080455" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "A0A3Q1ML53", "ENSBTAT00000083153", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "A0A3Q1ML53", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "ENSBTAT00000040104" ] }, "reaction_10081305": { "compartment": "compartment_74700", "id": "reaction_10081305", "reactome": "R-BTA-6801195", "name": "STEAP3 binds BNIP3L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081301", "species_10052892" ], "products": [ "species_10081303" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033862", "ENSBTAT00000077862", "A0A3Q1LPT9", "ENSBTAT00000077862", "Q3T013", "ENSBTAT00000033862" ] }, "reaction_10081323": { "compartment": "compartment_17927", "id": "reaction_10081323", "reactome": "R-BTA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081319", "species_10081309" ], "products": [ "species_10081321" ], "modifiers": [], "additional_components": [ "Q32KN9", "ENSBTAT00000006594", "ENSBTAT00000016994", "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10081326": { "compartment": "compartment_17906", "id": "reaction_10081326", "reactome": "R-BTA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10081321", "catalyst" ] ], "additional_components": [ "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10080738": { "compartment": "compartment_70101", "id": "reaction_10080738", "reactome": "R-BTA-6799466", "name": "TP53I3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080734" ], "products": [ "species_10080736" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004413", "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10080789": { "compartment": "compartment_70101", "id": "reaction_10080789", "reactome": "R-BTA-6799722", "name": "TP53I3 oxidoreductase generates unstable semiquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6799725", "species_29364" ], "products": [ "species_6799726", "species_29366" ], "modifiers": [ [ "species_10080736", "catalyst" ] ], "additional_components": [ "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10056702": { "compartment": "compartment_70101", "id": "reaction_10056702", "reactome": "R-BTA-1234164", "name": "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056667" ], "products": [ "species_29434", "species_10056691", "species_113528" ], "modifiers": [ [ "species_10056699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075132", "ENSBTAT00000075132", "species_198836", "species_71067", "F1MG82", "ENSBTAT00000000101" ] }, "reaction_10056679": { "compartment": "compartment_70101", "id": "reaction_10056679", "reactome": "R-BTA-1234161", "name": "HIF-alpha translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056671" ], "products": [ "species_10056677" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056761": { "compartment": "compartment_70101", "id": "reaction_10056761", "reactome": "R-BTA-1234183", "name": "Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056629", "species_10056659" ], "products": [ "species_10056685" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056719": { "compartment": "compartment_7660", "id": "reaction_10056719", "reactome": "R-BTA-1234165", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056675", "species_113671", "species_113685" ], "products": [ "species_10056704", "species_159942", "species_159939" ], "modifiers": [ [ "species_10056716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_71067", "A0A3Q1LUX2", "ENSBTAT00000072600", "species_198836", "A7MBA0", "ENSBTAT00000010744" ] }, "reaction_10056737": { "compartment": "compartment_7660", "id": "reaction_10056737", "reactome": "R-BTA-1234169", "name": "Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056723", "species_10056733" ], "products": [ "species_10056735" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056688": { "compartment": "compartment_70101", "id": "reaction_10056688", "reactome": "R-BTA-1234163", "name": "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056685", "species_10056683" ], "products": [ "species_10056661", "species_10056681" ], "modifiers": [ [ "species_10056685", "catalyst" ] ], "additional_components": [ "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056754": { "compartment": "compartment_7660", "id": "reaction_10056754", "reactome": "R-BTA-1234172", "name": "Nuclear VBC complex ubiquitinylates HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056735", "species_10056747" ], "products": [ "species_10056751", "species_10056745" ], "modifiers": [ [ "species_10056735", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056757": { "compartment": "compartment_70101", "id": "reaction_10056757", "reactome": "R-BTA-1234173", "name": "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056669" ], "products": [ "species_29434", "species_10056627", "species_113528" ], "modifiers": [ [ "species_10056659", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10056759": { "compartment": "compartment_70101", "id": "reaction_10056759", "reactome": "R-BTA-1234175", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056751" ], "products": [ "species_10056633" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10044776": { "compartment": "compartment_70101", "id": "reaction_10044776", "reactome": "R-BTA-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044772", "species_10033775" ], "products": [ "species_10044774" ], "modifiers": [], "additional_components": [ "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000005575", "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044794": { "compartment": "compartment_70101", "id": "reaction_10044794", "reactome": "R-BTA-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044774", "species_10044788" ], "products": [ "species_10044792" ], "modifiers": [], "additional_components": [ "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000072826", "P27117", "ENSBTAT00000005575", "A3KMV9", "ENSBTAT00000072826", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044784": { "compartment": "compartment_70101", "id": "reaction_10044784", "reactome": "R-BTA-350578", "name": "NQO1 interaction with ODC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033775", "species_10044780" ], "products": [ "species_10044782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005575", "ENSBTAT00000079752", "A0A3Q1MK02", "ENSBTAT00000079752", "P27117", "ENSBTAT00000005575" ] }, "reaction_10047519": { "compartment": "compartment_70101", "id": "reaction_10047519", "reactome": "R-BTA-392513", "name": "Rap1 signal termination by Rap1GAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045005" ], "products": [ "species_111294", "species_10045007" ], "modifiers": [ [ "species_10047512", "catalyst" ], [ "species_10047517", "inhibitor" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "A0A3Q1MI55", "ENSBTAT00000066483", "A0A3Q1MTG9", "ENSBTAT00000077316", "A0A3Q1LME0", "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439" ] }, "reaction_10047536": { "compartment": "compartment_70101", "id": "reaction_10047536", "reactome": "R-BTA-392834", "name": "Activation of EPACs by cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10047532" ], "products": [ "species_10047534" ], "modifiers": [], "additional_components": [ "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389" ] }, "reaction_10052466": { "compartment": "compartment_70101", "id": "reaction_10052466", "reactome": "R-BTA-913993", "name": "14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_10047515" ], "products": [ "species_10047517" ], "modifiers": [ [ "species_10052464", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439", "ENSBTAT00000075439" ] }, "reaction_10052471": { "compartment": "compartment_70101", "id": "reaction_10052471", "reactome": "R-BTA-913996", "name": "PKA/PKG phosphorylate Rap1GAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_113592" ], "products": [ "species_29370", "species_10052464" ], "modifiers": [ [ "species_427893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075439", "ENSBTAT00000075439", "ENSBTAT00000030539" ] }, "reaction_10071800": { "compartment": "compartment_70101", "id": "reaction_10071800", "reactome": "R-BTA-5577050", "name": "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071797", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1LPA7", "ENSBTAT00000069177" ] }, "reaction_10059961": { "compartment": "compartment_70101", "id": "reaction_10059961", "reactome": "R-BTA-1605723", "name": "Neu5Ac is cleaved from GM3 by NEU2 to form a globoside (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605590", "species_29356" ], "products": [ "species_428633", "species_1605647" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027552" ] }, "reaction_10071483": { "compartment": "compartment_70101", "id": "reaction_10071483", "reactome": "R-BTA-5339535", "name": "GLTPD1 transports C1P from plasma membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1638840" ], "products": [ "species_5339515" ], "modifiers": [ [ "species_10071480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010025" ] }, "reaction_10084410": { "compartment": "compartment_20699", "id": "reaction_10084410", "reactome": "R-BTA-8856223", "name": "B4GALNT1 dimer transfers GalNAc from UDP-GalNAc to GM3 and GD3 gangliosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_8856243" ], "products": [ "species_8856242", "species_205687" ], "modifiers": [ [ "species_10084407", "catalyst" ] ], "additional_components": [ "species_1605641", "CHEBI:28424", "species_1605610", "CHEBI:28648", "Q58DI2", "ENSBTAT00000005893" ] }, "reaction_10060316": { "compartment": "compartment_876", "id": "reaction_10060316", "reactome": "R-BTA-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060313", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002552" ] }, "reaction_10059984": { "compartment": "compartment_70101", "id": "reaction_10059984", "reactome": "R-BTA-1605768", "name": "Neu5Ac is cleaved from GM3 by NEU3 to form globoside (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1605649" ], "products": [ "species_428633", "species_1605618" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036738" ] }, "reaction_10059954": { "compartment": "compartment_161320", "id": "reaction_10059954", "reactome": "R-BTA-1605717", "name": "Ganglioside GM2 activator presents GM2 to hexosaminidase for cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059927", "species_1605610" ], "products": [ "species_10059929" ], "modifiers": [ [ "species_10059927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029099", "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099" ] }, "reaction_10060021": { "compartment": "compartment_876", "id": "reaction_10060021", "reactome": "R-BTA-1606583", "name": "Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429807" ], "products": [ "species_1606609", "species_1861754" ], "modifiers": [ [ "species_10060018", "catalyst" ] ], "additional_components": [] }, "reaction_10060309": { "compartment": "compartment_876", "id": "reaction_10060309", "reactome": "R-BTA-1638845", "name": "CERK phosphorylates CERA to form C1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429807", "species_113592" ], "products": [ "species_29370", "species_1638840" ], "modifiers": [ [ "species_10060306", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064397" ] }, "reaction_10059991": { "compartment": "compartment_161320", "id": "reaction_10059991", "reactome": "R-BTA-1605797", "name": "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605713" ], "products": [ "species_1605750", "species_1605673" ], "modifiers": [ [ "species_10059988", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020758" ] }, "reaction_10059977": { "compartment": "compartment_161320", "id": "reaction_10059977", "reactome": "R-BTA-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605637", "species_1605601" ], "modifiers": [ [ "species_10059974", "catalyst" ] ], "additional_components": [ "E1B725", "ENSBTAT00000025636" ] }, "reaction_10060041": { "compartment": "compartment_12045", "id": "reaction_10060041", "reactome": "R-BTA-1606839", "name": "Steryl sulfatase hydrolyses sulfate from steroid sulfates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_1609648" ], "products": [ "species_1609650", "species_1609649" ], "modifiers": [ [ "species_10060038", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LZ44", "ENSBTAT00000081469" ] }, "reaction_10071497": { "compartment": "compartment_876", "id": "reaction_10071497", "reactome": "R-BTA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10071494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003355" ] }, "reaction_10059944": { "compartment": "compartment_161320", "id": "reaction_10059944", "reactome": "R-BTA-1605595", "name": "Hexosaminidase A cleaves GalNAc from GM2 to form GM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10059929" ], "products": [ "species_10059927", "species_1605658", "species_1605641" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099", "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060012": { "compartment": "compartment_876", "id": "reaction_10060012", "reactome": "R-BTA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060009", "catalyst" ] ], "additional_components": [ "species_29926", "F1N588", "ENSBTAT00000010706" ] }, "reaction_10059951": { "compartment": "compartment_161320", "id": "reaction_10059951", "reactome": "R-BTA-1605632", "name": "Both hexosaminidase A and B can cleave GalNAc from globoside", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605608" ], "products": [ "species_1605716", "species_1605658" ], "modifiers": [ [ "species_10059948", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411", "Q0V8R6", "ENSBTAT00000017261" ] }, "reaction_10060302": { "compartment": "compartment_20699", "id": "reaction_10060302", "reactome": "R-BTA-1638104", "name": "Ceramide glucosyltransferase (UGCG) catalyses the transfer of glucose to ceramide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744227", "species_428270" ], "products": [ "species_1660674", "species_205687" ], "modifiers": [ [ "species_10060299", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043826" ] }, "reaction_10059968": { "compartment": "compartment_161320", "id": "reaction_10059968", "reactome": "R-BTA-1605724", "name": "Neu5Ac is cleaved from GM3 by NEU1 and 4 to form a globoside (lysosomal lumen)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605641" ], "products": [ "species_1605601", "species_428639" ], "modifiers": [ [ "species_10059965", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019755" ] }, "reaction_10048986": { "compartment": "compartment_70101", "id": "reaction_10048986", "reactome": "R-BTA-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428671", "species_428686" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049116": { "compartment": "compartment_12045", "id": "reaction_10049116", "reactome": "R-BTA-429683", "name": "CERT:ceramide [ER] => ceramide [Golgi] + CERT [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049108" ], "products": [ "species_10049110", "species_428270" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000027095" ] }, "reaction_10048860": { "compartment": "compartment_70101", "id": "reaction_10048860", "reactome": "R-BTA-428127", "name": "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_9695889" ], "products": [ "species_113528", "species_76194", "species_428182" ], "modifiers": [ [ "species_10048843", "catalyst" ], [ "species_10048858", "inhibitor" ] ], "additional_components": [ "Q5E978", "ENSBTAT00000018578", "Q0IIK4", "ENSBTAT00000085219", "Q3MHG1", "ENSBTAT00000002872", "A5PKM3", "ENSBTAT00000027289", "Q0VD15", "ENSBTAT00000018402", "Q29RQ9", "ENSBTAT00000016673", "Q5E972", "ENSBTAT00000027540" ] }, "reaction_10048988": { "compartment": "compartment_70101", "id": "reaction_10048988", "reactome": "R-BTA-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049182": { "compartment": "compartment_876", "id": "reaction_10049182", "reactome": "R-BTA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10049179", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072919" ] }, "reaction_10048978": { "compartment": "compartment_70101", "id": "reaction_10048978", "reactome": "R-BTA-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428275" ], "products": [ "species_29372", "species_428694" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10048917": { "compartment": "compartment_70101", "id": "reaction_10048917", "reactome": "R-BTA-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9025544" ], "products": [ "species_428237", "species_3632878" ], "modifiers": [ [ "species_10048914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052101" ] }, "reaction_10049161": { "compartment": "compartment_70101", "id": "reaction_10049161", "reactome": "R-BTA-429730", "name": "multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049158", "species_29356" ], "products": [ "species_10049110", "species_29372" ], "modifiers": [ [ "species_10049158", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10049163": { "compartment": "compartment_70101", "id": "reaction_10049163", "reactome": "R-BTA-429732", "name": "multiphospho-CERT + PPM1L:VAPA/B => multiphospho-CERT:PPM1L:VAPA/B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049100", "species_10049147" ], "products": [ "species_10049158" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10082058": { "compartment": "compartment_13977", "id": "reaction_10082058", "reactome": "R-BTA-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6808468", "species_29360" ], "products": [ "species_2453691", "species_70106", "species_73473" ], "modifiers": [ [ "species_10082055", "catalyst" ] ], "additional_components": [ "A0A3Q1M3Q4", "ENSBTAT00000085198", "Q1JPA0", "ENSBTAT00000076578" ] }, "reaction_10048910": { "compartment": "compartment_70101", "id": "reaction_10048910", "reactome": "R-BTA-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428126", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9025544" ], "modifiers": [ [ "species_10048907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012243" ] }, "reaction_10048896": { "compartment": "compartment_70101", "id": "reaction_10048896", "reactome": "R-BTA-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428163" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10048893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074462" ] }, "reaction_10049154": { "compartment": "compartment_70101", "id": "reaction_10049154", "reactome": "R-BTA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049124", "species_113592" ], "products": [ "species_29370", "species_10049147" ], "modifiers": [ [ "species_10049151", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "ENSBTAT00000022345" ] }, "reaction_10048903": { "compartment": "compartment_70101", "id": "reaction_10048903", "reactome": "R-BTA-428231", "name": "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428256" ], "products": [ "species_428193", "species_428198" ], "modifiers": [ [ "species_10048900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010648" ] }, "reaction_10048889": { "compartment": "compartment_20699", "id": "reaction_10048889", "reactome": "R-BTA-428205", "name": "ceramide + H2O => stearate + sphingosine [Golgi]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428270" ], "products": [ "species_428248", "species_8934421" ], "modifiers": [ [ "species_10048886", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014354" ] }, "reaction_10048882": { "compartment": "compartment_70101", "id": "reaction_10048882", "reactome": "R-BTA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10048879", "catalyst" ] ], "additional_components": [ "A0A3Q1MVP2", "ENSBTAT00000082150", "A0A3Q1MJ30", "ENSBTAT00000080491", "A4FUG2", "ENSBTAT00000036524", "A5D7K4", "ENSBTAT00000052579" ] }, "reaction_10049141": { "compartment": "compartment_70101", "id": "reaction_10049141", "reactome": "R-BTA-429698", "name": "PRKD1,2,3 phosphorylates COL4A3BP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049119" ], "products": [ "species_10049124", "species_29370" ], "modifiers": [ [ "species_10049138", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "A0A3Q1N9F5", "ENSBTAT00000081006", "F1MIA2", "ENSBTAT00000020721", "E1B7L9", "ENSBTAT00000070039" ] }, "reaction_10049143": { "compartment": "compartment_12045", "id": "reaction_10049143", "reactome": "R-BTA-429699", "name": "CERT [ER] + ceramide [ER] => CERT:ceramide [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110", "species_428256" ], "products": [ "species_10049108" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10076151": { "compartment": "compartment_12045", "id": "reaction_10076151", "reactome": "R-BTA-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428671", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076148", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10049004": { "compartment": "compartment_70101", "id": "reaction_10049004", "reactome": "R-BTA-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10049001", "catalyst" ] ], "additional_components": [ "A0A3Q1MIK4", "ENSBTAT00000069794", "Q3SZE3", "ENSBTAT00000015460" ] }, "reaction_10049007": { "compartment": "compartment_70101", "id": "reaction_10049007", "reactome": "R-BTA-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10049121": { "compartment": "compartment_70101", "id": "reaction_10049121", "reactome": "R-BTA-429694", "name": "CERT:PPM1L:VAPA/B [ER] => CERT [cytosol] + PPM1L:VAPA/B [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110" ], "products": [ "species_10049119", "species_10049100" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250" ] }, "reaction_10076833": { "compartment": "compartment_876", "id": "reaction_10076833", "reactome": "R-BTA-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428663", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076830", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076578" ] }, "reaction_10091936": { "compartment": "compartment_70101", "id": "reaction_10091936", "reactome": "R-BTA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10091933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009765" ] }, "reaction_10048995": { "compartment": "compartment_984", "id": "reaction_10048995", "reactome": "R-BTA-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10048992", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069794" ] }, "reaction_10076389": { "compartment": "compartment_12045", "id": "reaction_10076389", "reactome": "R-BTA-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10076386", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016212" ] }, "reaction_10049189": { "compartment": "compartment_20699", "id": "reaction_10049189", "reactome": "R-BTA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10049186", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082007" ] }, "reaction_10091941": { "compartment": "compartment_70101", "id": "reaction_10091941", "reactome": "R-BTA-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_428203", "species_29370" ], "modifiers": [ [ "species_10048893", "catalyst" ], [ "species_10091939", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000074462", "A0A3Q1MBG6", "ENSBTAT00000074462" ] }, "reaction_10043933": { "compartment": "compartment_70101", "id": "reaction_10043933", "reactome": "R-BTA-209823", "name": "Tyrosine is hydroxylated to dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29368", "species_29506" ], "products": [ "species_209849", "species_71112" ], "modifiers": [ [ "species_10043930", "catalyst" ] ], "additional_components": [ "A0A3Q1MAN0", "ENSBTAT00000077835", "species_71067" ] }, "reaction_10073477": { "compartment": "compartment_5668572", "id": "reaction_10073477", "reactome": "R-BTA-5662660", "name": "Dopachrome is transformed to DHICA by DCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5662665" ], "products": [ "species_5662670" ], "modifiers": [ [ "species_10073474", "catalyst" ] ], "additional_components": [ "F1MC37", "ENSBTAT00000034881", "species_29426" ] }, "reaction_10044216": { "compartment": "compartment_17960", "id": "reaction_10044216", "reactome": "R-BTA-211924", "name": "CYP4B1 12-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215075" ], "modifiers": [ [ "species_10044213", "catalyst" ] ], "additional_components": [ "Q148E6", "ENSBTAT00000015892" ] }, "reaction_10044195": { "compartment": "compartment_17960", "id": "reaction_10044195", "reactome": "R-BTA-211904", "name": "CYP4F12 18-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_352318" ], "modifiers": [ [ "species_10044192", "catalyst" ] ], "additional_components": [ "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "A0A3Q1MCJ2", "ENSBTAT00000073532", "M0QW30", "ENSBTAT00000072981" ] }, "reaction_10044260": { "compartment": "compartment_17960", "id": "reaction_10044260", "reactome": "R-BTA-211983", "name": "CYP2J2 oxidises ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215062" ], "modifiers": [ [ "species_10044257", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34157", "species_2142739", "CHEBI:34490", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10035958": { "compartment": "compartment_17960", "id": "reaction_10035958", "reactome": "R-BTA-76466", "name": "CYP4A11 12-hydroxylates DDCX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_33549", "species_113601" ], "products": [ "species_113519", "species_113564", "species_42373" ], "modifiers": [ [ "species_10035955", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785" ] }, "reaction_10048504": { "compartment": "compartment_876", "id": "reaction_10048504", "reactome": "R-BTA-425661", "name": "SLC8A1,2,3 exchange 3Na+ for Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_74113" ], "products": [ "species_83910", "species_74112" ], "modifiers": [ [ "species_10048501", "catalyst" ], [ "species_10037000", "inhibitor" ] ], "additional_components": [ "E1B7D0", "ENSBTAT00000014410", "A0A3Q1LST7", "ENSBTAT00000077819", "ENSBTAT00000044622" ] }, "reaction_10072522": { "compartment": "compartment_263163", "id": "reaction_10072522", "reactome": "R-BTA-5626316", "name": "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5626313", "species_83910", "species_167012" ], "products": [ "species_29804", "species_74016", "species_425958" ], "modifiers": [ [ "species_10072519", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006382" ] }, "reaction_10048526": { "compartment": "compartment_876", "id": "reaction_10048526", "reactome": "R-BTA-425678", "name": "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_74016", "species_74113" ], "products": [ "species_74126", "species_83910", "species_74112" ], "modifiers": [ [ "species_10048523", "catalyst" ] ], "additional_components": [ "F1MD60", "ENSBTAT00000008703", "A0A3Q1M073", "ENSBTAT00000074844", "E1BM98", "ENSBTAT00000061324", "E1BGG7", "ENSBTAT00000015768" ] }, "reaction_10048533": { "compartment": "compartment_876", "id": "reaction_10048533", "reactome": "R-BTA-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425815", "species_74016" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10048530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10038895": { "compartment": "compartment_70616", "id": "reaction_10038895", "reactome": "R-BTA-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_113529", "species_29362" ], "products": [ "species_76633", "species_113526", "species_163953" ], "modifiers": [ [ "species_10038882", "catalyst" ], [ "species_10038893", "catalyst" ] ], "additional_components": [ "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219", "Q85BD6", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "P03910", "ENSBTAT00000060552", "F1MK72", "ENSBTAT00000006115", "Q1RMM6", "ENSBTAT00000005722" ] }, "reaction_10080521": { "compartment": "compartment_70616", "id": "reaction_10080521", "reactome": "R-BTA-6799202", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080503", "species_10080485" ], "products": [ "species_10080505" ], "modifiers": [], "additional_components": [ "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10080515": { "compartment": "compartment_70616", "id": "reaction_10080515", "reactome": "R-BTA-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038704", "species_10080511", "species_10080507" ], "products": [ "species_10080513" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077219", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219" ] }, "reaction_10080517": { "compartment": "compartment_70616", "id": "reaction_10080517", "reactome": "R-BTA-6799197", "name": "ND4, ND5 bind the 550kDa complex to form the 815kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038708", "species_10038712", "species_10080505" ], "products": [ "species_10080507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060552", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552" ] }, "reaction_10080519": { "compartment": "compartment_70616", "id": "reaction_10080519", "reactome": "R-BTA-6799199", "name": "COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038740", "species_10080501", "species_10038720", "species_10038716", "species_10038730" ], "products": [ "species_10080503" ], "modifiers": [], "additional_components": [ "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "ENSBTAT00000007761", "ENSBTAT00000060562", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10038647": { "compartment": "compartment_70616", "id": "reaction_10038647", "reactome": "R-BTA-163214", "name": "Electron transfer from reduced cytochrome c to molecular oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10038546", "species_113529" ], "products": [ "species_10038548", "species_163953", "species_113521" ], "modifiers": [ [ "species_10038606", "catalyst" ], [ "species_10038643", "catalyst" ], [ "species_10038611", "catalyst" ], [ "species_10038625", "catalyst" ], [ "species_10038645", "inhibitor" ] ], "additional_components": [ "CHEBI:38573", "P62894", "ENSBTAT00000007918", "P62894", "ENSBTAT00000007918", "CHEBI:38574", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "A6H784", "ENSBTAT00000016742", "A0A3Q1MQS6", "ENSBTAT00000067855", "E1BJK7", "ENSBTAT00000013031", "E1BPX9", "ENSBTAT00000021773", "ENSBTAT00000020289", "A0A3Q1MMW4", "ENSBTAT00000082257", "F1N5P2", "ENSBTAT00000007094", "Q1RMH3", "ENSBTAT00000001069", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10084313": { "compartment": "compartment_70101", "id": "reaction_10084313", "reactome": "R-BTA-8854981", "name": "SHC1 in the RET complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084133" ], "products": [ "species_10074027" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084185": { "compartment": "compartment_70101", "id": "reaction_10084185", "reactome": "R-BTA-8853774", "name": "GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084177" ], "products": [ "species_10084183", "species_29370" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084153": { "compartment": "compartment_70101", "id": "reaction_10084153", "reactome": "R-BTA-8853755", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043197", "species_10074025" ], "products": [ "species_10084151" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10085755": { "compartment": "compartment_876", "id": "reaction_10085755", "reactome": "R-BTA-8871226", "name": "RET binds GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074005", "species_10084137" ], "products": [ "species_10084157" ], "modifiers": [], "additional_components": [ "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398" ] }, "reaction_10084187": { "compartment": "compartment_984", "id": "reaction_10084187", "reactome": "R-BTA-8853789", "name": "GDNF,NRTN bind RET:GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073999", "species_10084157" ], "products": [ "species_10084159" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528" ] }, "reaction_10084379": { "compartment": "compartment_70101", "id": "reaction_10084379", "reactome": "R-BTA-8855747", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084375", "species_10074025" ], "products": [ "species_10084377" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316" ] }, "reaction_10085757": { "compartment": "compartment_876", "id": "reaction_10085757", "reactome": "R-BTA-8871227", "name": "RET binds GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074017", "species_10084137" ], "products": [ "species_10084161" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066172", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084190": { "compartment": "compartment_876", "id": "reaction_10084190", "reactome": "R-BTA-8853792", "name": "RET tyrosine phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084167", "species_113592" ], "products": [ "species_29370", "species_10074025" ], "modifiers": [ [ "species_10084167", "catalyst" ] ], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084309": { "compartment": "compartment_70101", "id": "reaction_10084309", "reactome": "R-BTA-8854897", "name": "p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10084175" ], "products": [ "species_10084177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084149": { "compartment": "compartment_70101", "id": "reaction_10084149", "reactome": "R-BTA-8853753", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10074025" ], "products": [ "species_10084147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10084311": { "compartment": "compartment_70101", "id": "reaction_10084311", "reactome": "R-BTA-8854899", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074025" ], "products": [ "species_10074031" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084169": { "compartment": "compartment_876", "id": "reaction_10084169", "reactome": "R-BTA-8853762", "name": "RET dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084165" ], "products": [ "species_10084167" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084393": { "compartment": "compartment_70101", "id": "reaction_10084393", "reactome": "R-BTA-8855915", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084389", "species_10074025" ], "products": [ "species_10084391" ], "modifiers": [], "additional_components": [ "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10084330": { "compartment": "compartment_984", "id": "reaction_10084330", "reactome": "R-BTA-8855564", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10074025" ], "products": [ "species_10084328" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10084141": { "compartment": "compartment_876", "id": "reaction_10084141", "reactome": "R-BTA-8853745", "name": "RET binds GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073976", "species_10084137" ], "products": [ "species_10084139" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083411", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411" ] }, "reaction_10084352": { "compartment": "compartment_70101", "id": "reaction_10084352", "reactome": "R-BTA-8855617", "name": "2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084348", "species_10074025" ], "products": [ "species_10084350" ], "modifiers": [], "additional_components": [ "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819" ] }, "reaction_10084131": { "compartment": "compartment_70101", "id": "reaction_10084131", "reactome": "R-BTA-8853734", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074027" ], "products": [ "species_10074029" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084194": { "compartment": "compartment_70101", "id": "reaction_10084194", "reactome": "R-BTA-8853793", "name": "p-5Y-RET complexes bind GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084192", "species_10035485" ], "products": [ "species_10084175" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084196": { "compartment": "compartment_984", "id": "reaction_10084196", "reactome": "R-BTA-8853800", "name": "ARTN binds RET:GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073972", "species_10084139" ], "products": [ "species_10084155" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023553", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553" ] }, "reaction_10084135": { "compartment": "compartment_70101", "id": "reaction_10084135", "reactome": "R-BTA-8853737", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035544", "species_10074025" ], "products": [ "species_10084133" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084198": { "compartment": "compartment_984", "id": "reaction_10084198", "reactome": "R-BTA-8853801", "name": "PSPN binds RET:GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084161", "species_10074013" ], "products": [ "species_10084163" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172", "ENSBTAT00000027984", "E1BCL0", "ENSBTAT00000027984", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084326": { "compartment": "compartment_876", "id": "reaction_10084326", "reactome": "R-BTA-8855508", "name": "p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10084183" ], "products": [ "species_10084324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10061049": { "compartment": "compartment_7660", "id": "reaction_10061049", "reactome": "R-BTA-1855206", "name": "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023891" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061017": { "compartment": "compartment_7660", "id": "reaction_10061017", "reactome": "R-BTA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061128": { "compartment": "compartment_7660", "id": "reaction_10061128", "reactome": "R-BTA-1855228", "name": "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023892" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061131": { "compartment": "compartment_7660", "id": "reaction_10061131", "reactome": "R-BTA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061052": { "compartment": "compartment_7660", "id": "reaction_10061052", "reactome": "R-BTA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061119": { "compartment": "compartment_7660", "id": "reaction_10061119", "reactome": "R-BTA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061137": { "compartment": "compartment_7660", "id": "reaction_10061137", "reactome": "R-BTA-1855233", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023907" ], "products": [ "species_113582", "species_2023891" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060993": { "compartment": "compartment_7660", "id": "reaction_10060993", "reactome": "R-BTA-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10060990", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10061031": { "compartment": "compartment_7660", "id": "reaction_10061031", "reactome": "R-BTA-1855185", "name": "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023935" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060951": { "compartment": "compartment_7660", "id": "reaction_10060951", "reactome": "R-BTA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10067955": { "compartment": "compartment_70101", "id": "reaction_10067955", "reactome": "R-BTA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067950" ], "products": [ "species_29372", "species_10067952" ], "modifiers": [ [ "species_10067950", "catalyst" ], [ "species_10067948", "catalyst" ] ], "additional_components": [ "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_29370", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890" ] }, "reaction_10068022": { "compartment": "compartment_70101", "id": "reaction_10068022", "reactome": "R-BTA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068020", "species_10068018" ], "products": [ "species_10067950" ], "modifiers": [], "additional_components": [ "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500" ] }, "reaction_10065708": { "compartment": "compartment_70101", "id": "reaction_10065708", "reactome": "R-BTA-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697" ], "products": [ "species_10065705" ], "modifiers": [ [ "species_10065697", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011761", "F1MW01", "ENSBTAT00000011761", "ENSBTAT00000011761" ] }, "reaction_10065726": { "compartment": "compartment_70101", "id": "reaction_10065726", "reactome": "R-BTA-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697", "species_10065722" ], "products": [ "species_10065724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011761", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "F1MW01", "ENSBTAT00000011761" ] }, "reaction_10091145": { "compartment": "compartment_70101", "id": "reaction_10091145", "reactome": "R-BTA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10091134" ], "products": [ "species_10091143" ], "modifiers": [], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438" ] }, "reaction_10091141": { "compartment": "compartment_1598585", "id": "reaction_10091141", "reactome": "R-BTA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043519" ], "products": [ "species_29420", "species_10091134" ], "modifiers": [ [ "species_10091138", "catalyst" ] ], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29420", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "ENSBTAT00000066656" ] }, "reaction_10091132": { "compartment": "compartment_13231", "id": "reaction_10091132", "reactome": "R-BTA-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10091128" ], "products": [ "species_10091130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "ENSBTAT00000011125", "A6QQV8", "ENSBTAT00000011125", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10091656": { "compartment": "compartment_70101", "id": "reaction_10091656", "reactome": "R-BTA-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091652", "species_10091648" ], "products": [ "species_10091654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065503", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "G3X8E2", "ENSBTAT00000065503" ] }, "reaction_10091658": { "compartment": "compartment_13231", "id": "reaction_10091658", "reactome": "R-BTA-9668395", "name": "CHMP7 binds CC2D1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091644", "species_10091640" ], "products": [ "species_10091646" ], "modifiers": [], "additional_components": [ "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000021129", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091661": { "compartment": "compartment_70101", "id": "reaction_10091661", "reactome": "R-BTA-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29356", "species_113592" ], "products": [ "species_29372", "species_10040834", "species_29370" ], "modifiers": [ [ "species_10091648", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091634": { "compartment": "compartment_70101", "id": "reaction_10091634", "reactome": "R-BTA-9668335", "name": "CHMP7 binds LEMD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052771", "species_10070769" ], "products": [ "species_10091632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017987", "ENSBTAT00000020642", "E1B828", "ENSBTAT00000020642", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091663": { "compartment": "compartment_7660", "id": "reaction_10091663", "reactome": "R-BTA-9668904", "name": "Formation of the CTF18 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039904", "species_10039900", "species_10039896" ], "products": [ "species_10039906" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020389", "ENSBTAT00000002226", "ENSBTAT00000026311", "E1B8Q4", "ENSBTAT00000026311", "P0CG11", "ENSBTAT00000002226", "F1MTU0", "ENSBTAT00000020389" ] }, "reaction_10057418": { "compartment": "compartment_876", "id": "reaction_10057418", "reactome": "R-BTA-1296046", "name": "KCNJs transport K+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10057415", "catalyst" ] ], "additional_components": [ "O19182", "ENSBTAT00000010914", "A0A3Q1M4V6", "ENSBTAT00000078632", "E1BCI4", "ENSBTAT00000000089" ] }, "reaction_10064591": { "compartment": "compartment_70616", "id": "reaction_10064591", "reactome": "R-BTA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10064588", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007549" ] }, "reaction_10046968": { "compartment": "compartment_70101", "id": "reaction_10046968", "reactome": "R-BTA-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389545", "species_29366" ], "products": [ "species_29406", "species_70106", "species_113528", "species_29364" ], "modifiers": [ [ "species_10046965", "catalyst" ] ], "additional_components": [ "A0A140T8A5", "ENSBTAT00000027348" ] }, "reaction_10058524": { "compartment": "compartment_70101", "id": "reaction_10058524", "reactome": "R-BTA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10058521", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411" ] }, "reaction_10058511": { "compartment": "compartment_70101", "id": "reaction_10058511", "reactome": "R-BTA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10058500", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ], [ "species_10058509", "inhibitor" ] ], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10058785": { "compartment": "compartment_70101", "id": "reaction_10058785", "reactome": "R-BTA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10058778" ], "products": [ "species_29370", "species_10058521" ], "modifiers": [ [ "species_10058782", "catalyst" ] ], "additional_components": [ "A0A3Q1MA59", "ENSBTAT00000030411", "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411", "ENSBTAT00000003877" ] }, "reaction_10058514": { "compartment": "compartment_70101", "id": "reaction_10058514", "reactome": "R-BTA-1474158", "name": "GCHFR binds to GCH1 and negatively regulates its activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058500", "species_10058507" ], "products": [ "species_10058509" ], "modifiers": [], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10085853": { "compartment": "compartment_70101", "id": "reaction_10085853", "reactome": "R-BTA-8874705", "name": "TTPA transports alpha-TOH from lysosomal membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085849" ], "products": [ "species_10085851" ], "modifiers": [], "additional_components": [ "species_8874708", "F1N086", "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10085855": { "compartment": "compartment_70101", "id": "reaction_10085855", "reactome": "R-BTA-8874718", "name": "TTPA binds alpha-TOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085847", "species_8874708" ], "products": [ "species_10085849" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10081928": { "compartment": "compartment_17957", "id": "reaction_10081928", "reactome": "R-BTA-6806647", "name": "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10081925", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064807" ] }, "reaction_10038427": { "compartment": "compartment_12045", "id": "reaction_10038427", "reactome": "R-BTA-159790", "name": "VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10038422", "catalyst" ], [ "species_10038425", "inhibitor" ] ], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10090493": { "compartment": "compartment_12045", "id": "reaction_10090493", "reactome": "R-BTA-9026967", "name": "VKORC1 inhibitors binds VKORC1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038422", "species_9035082" ], "products": [ "species_10038425" ], "modifiers": [], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10081935": { "compartment": "compartment_17957", "id": "reaction_10081935", "reactome": "R-BTA-6806674", "name": "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806891", "species_6806657" ], "products": [ "species_6806362", "species_6806656" ], "modifiers": [ [ "species_10081932", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018617" ] }, "reaction_10054393": { "compartment": "compartment_70101", "id": "reaction_10054393", "reactome": "R-BTA-975629", "name": "RDH11 reduces RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10035574", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "ENSBTAT00000002535" ] }, "reaction_10066249": { "compartment": "compartment_70101", "id": "reaction_10066249", "reactome": "R-BTA-2855259", "name": "atROL binds RBP1 (parenchymal cell)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473610", "species_10035554" ], "products": [ "species_10065443" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590" ] }, "reaction_10054395": { "compartment": "compartment_70101", "id": "reaction_10054395", "reactome": "R-BTA-975633", "name": "atROL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975590" ], "products": [ "species_10054388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10070971": { "compartment": "compartment_984", "id": "reaction_10070971", "reactome": "R-BTA-5246478", "name": "APOM binds retinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070967", "species_5246487" ], "products": [ "species_10070969" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075540", "species_975590", "species_5362520", "species_215573", "species_975590", "species_5362520", "species_215573", "A0A3Q1MB70", "ENSBTAT00000075540" ] }, "reaction_10065437": { "compartment": "compartment_70101", "id": "reaction_10065437", "reactome": "R-BTA-2399913", "name": "atRAL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975622" ], "products": [ "species_10054390" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975622", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10069948": { "compartment": "compartment_5460", "id": "reaction_10069948", "reactome": "R-BTA-5164399", "name": "BCO2:Fe2+ cleaves betaC to APO10al and bION", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_5164389" ], "products": [ "species_5164390", "species_5164383" ], "modifiers": [ [ "species_10069945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N2Z9", "ENSBTAT00000048395" ] }, "reaction_10054382": { "compartment": "compartment_984", "id": "reaction_10054382", "reactome": "R-BTA-975594", "name": "PLB1 hydrolyses RPALM to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10065441": { "compartment": "compartment_70101", "id": "reaction_10065441", "reactome": "R-BTA-2404142", "name": "atROL binds RBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473616" ], "products": [ "species_10065439" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065445": { "compartment": "compartment_70101", "id": "reaction_10065445", "reactome": "R-BTA-2404144", "name": "Parenchymal atROL translocates to HSCs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065443" ], "products": [ "species_10035554", "species_2473616" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10054404": { "compartment": "compartment_70101", "id": "reaction_10054404", "reactome": "R-BTA-975635", "name": "BCMO1:Fe2+ cleaves betaC to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_975643" ], "products": [ "species_975622" ], "modifiers": [ [ "species_10054401", "catalyst" ] ], "additional_components": [ "F1N3B7", "ENSBTAT00000048748", "species_71067" ] }, "reaction_10054375": { "compartment": "compartment_984", "id": "reaction_10054375", "reactome": "R-BTA-975593", "name": "PNLIP:CLPS hydrolyses RPALM to atROL and PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10066247": { "compartment": "compartment_70101", "id": "reaction_10066247", "reactome": "R-BTA-2855252", "name": "AKRs reduce RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10066244", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086", "F1N678", "ENSBTAT00000002073" ] }, "reaction_10042657": { "compartment": "compartment_876", "id": "reaction_10042657", "reactome": "R-BTA-199219", "name": "SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199238", "species_74113" ], "products": [ "species_83910", "species_199207" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10066401": { "compartment": "compartment_70101", "id": "reaction_10066401", "reactome": "R-BTA-2993447", "name": "HLCS biotinylates 6x(PCCA:PCCB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066388", "species_113592", "species_199207" ], "products": [ "species_111294", "species_10066394", "species_76577" ], "modifiers": [ [ "species_10066398", "catalyst" ] ], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "ENSBTAT00000057284" ] }, "reaction_10067733": { "compartment": "compartment_70101", "id": "reaction_10067733", "reactome": "R-BTA-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066394" ], "products": [ "species_10033909" ], "modifiers": [], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10042936": { "compartment": "compartment_70616", "id": "reaction_10042936", "reactome": "R-BTA-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10042933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048106" ] }, "reaction_10081339": { "compartment": "compartment_5460", "id": "reaction_10081339", "reactome": "R-BTA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10042940": { "compartment": "compartment_876", "id": "reaction_10042940", "reactome": "R-BTA-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10082078": { "compartment": "compartment_70101", "id": "reaction_10082078", "reactome": "R-BTA-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111353", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_197969" ], "modifiers": [ [ "species_10082075", "catalyst" ] ], "additional_components": [ "E1BMG9", "ENSBTAT00000043693" ] }, "reaction_10042929": { "compartment": "compartment_876", "id": "reaction_10042929", "reactome": "R-BTA-200652", "name": "SLC19A1 transports 5-methyl-THF from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200709" ], "products": [ "species_200665" ], "modifiers": [ [ "species_10042926", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082124" ] }, "reaction_10041840": { "compartment": "compartment_70101", "id": "reaction_10041840", "reactome": "R-BTA-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73604", "species_29364" ], "products": [ "species_111355", "species_29366" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10087442": { "compartment": "compartment_984", "id": "reaction_10087442", "reactome": "R-BTA-8942344", "name": "FOLR2 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086761" ], "products": [ "species_197965", "species_10086759" ], "modifiers": [], "additional_components": [ "Q0VCN9", "ENSBTAT00000027602", "species_197965", "ENSBTAT00000027602" ] }, "reaction_10092306": { "compartment": "compartment_70101", "id": "reaction_10092306", "reactome": "R-BTA-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10092303", "catalyst" ] ], "additional_components": [ "A0A140T872", "ENSBTAT00000010103" ] }, "reaction_10082068": { "compartment": "compartment_5460", "id": "reaction_10082068", "reactome": "R-BTA-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_6808499", "species_113521" ], "products": [ "species_113529", "species_200679", "species_113600", "species_29376" ], "modifiers": [ [ "species_10082065", "catalyst" ] ], "additional_components": [ "E1BDG9", "ENSBTAT00000008298" ] }, "reaction_10086763": { "compartment": "compartment_984", "id": "reaction_10086763", "reactome": "R-BTA-8940134", "name": "FOLR2 binds FOLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716", "species_10086759" ], "products": [ "species_10086761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027602", "Q0VCN9", "ENSBTAT00000027602", "species_197965" ] }, "reaction_10042922": { "compartment": "compartment_876", "id": "reaction_10042922", "reactome": "R-BTA-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10041838": { "compartment": "compartment_70101", "id": "reaction_10041838", "reactome": "R-BTA-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10081346": { "compartment": "compartment_70101", "id": "reaction_10081346", "reactome": "R-BTA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10081343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026669" ] }, "reaction_10076485": { "compartment": "compartment_70616", "id": "reaction_10076485", "reactome": "R-BTA-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_5693984", "species_113521" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10076482", "catalyst" ] ], "additional_components": [ "Q3SZ20", "ENSBTAT00000038244" ] }, "reaction_10081349": { "compartment": "compartment_5460", "id": "reaction_10081349", "reactome": "R-BTA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10041817": { "compartment": "compartment_70101", "id": "reaction_10041817", "reactome": "R-BTA-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10041814", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1NKT9", "ENSBTAT00000069099" ] }, "reaction_10042906": { "compartment": "compartment_5460", "id": "reaction_10042906", "reactome": "R-BTA-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938078", "species_8938090" ], "modifiers": [ [ "species_10042903", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NCV5", "ENSBTAT00000074137" ] }, "reaction_10088666": { "compartment": "compartment_5460", "id": "reaction_10088666", "reactome": "R-BTA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10088663", "catalyst" ] ], "additional_components": [ "A0A3Q1LR42", "ENSBTAT00000077253" ] }, "reaction_10086748": { "compartment": "compartment_984", "id": "reaction_10086748", "reactome": "R-BTA-8940070", "name": "NT5E:Zn2+ hydrolyses NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_109277", "species_8940067" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10086750": { "compartment": "compartment_984", "id": "reaction_10086750", "reactome": "R-BTA-8940074", "name": "NT5E:Zn2+ hydrolyses NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8940067" ], "products": [ "species_109277", "species_8940077" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10085374": { "compartment": "compartment_984", "id": "reaction_10085374", "reactome": "R-BTA-8870346", "name": "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10085371", "catalyst" ] ], "additional_components": [ "F1MLP3", "ENSBTAT00000008097" ] }, "reaction_10085362": { "compartment": "compartment_70101", "id": "reaction_10085362", "reactome": "R-BTA-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10085365": { "compartment": "compartment_70101", "id": "reaction_10085365", "reactome": "R-BTA-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10081977": { "compartment": "compartment_5460", "id": "reaction_10081977", "reactome": "R-BTA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10081974", "catalyst" ] ], "additional_components": [ "A0A3Q1MF13", "ENSBTAT00000080451" ] }, "reaction_10071643": { "compartment": "compartment_70101", "id": "reaction_10071643", "reactome": "R-BTA-5359451", "name": "NNMT transfers CH3 from SAM to NAM to form MNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197277", "species_71284" ], "products": [ "species_549282", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10086623": { "compartment": "compartment_70101", "id": "reaction_10086623", "reactome": "R-BTA-8938073", "name": "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938276", "species_29360" ], "products": [ "species_197277", "species_8938282" ], "modifiers": [ [ "species_10086620", "catalyst" ] ], "additional_components": [ "F6R6Y8", "ENSBTAT00000029045", "A0A3Q1M0E5", "ENSBTAT00000084343", "F1MRP9", "ENSBTAT00000012765" ] }, "reaction_10082143": { "compartment": "compartment_17951", "id": "reaction_10082143", "reactome": "R-BTA-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192305", "species_389620" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10082140", "catalyst" ] ], "additional_components": [ "ENSBTAT00000039965" ] }, "reaction_10041824": { "compartment": "compartment_70101", "id": "reaction_10041824", "reactome": "R-BTA-197250", "name": "NAMPT transfers PRIB to NAM to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197277" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041821", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083136" ] }, "reaction_10041808": { "compartment": "compartment_70101", "id": "reaction_10041808", "reactome": "R-BTA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041805", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "A0A3Q1N5S3", "ENSBTAT00000084634" ] }, "reaction_10081984": { "compartment": "compartment_5460", "id": "reaction_10081984", "reactome": "R-BTA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10081981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015238" ] }, "reaction_10088867": { "compartment": "compartment_984", "id": "reaction_10088867", "reactome": "R-BTA-8956458", "name": "RNLS:FAD oxidises dh-beta-NAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_352327", "species_8956473" ], "products": [ "species_352330", "species_351629" ], "modifiers": [ [ "species_10088864", "catalyst" ] ], "additional_components": [ "CHEBI:90174", "CHEBI:90171", "A0A3Q1NF84", "ENSBTAT00000069540", "species_113596" ] }, "reaction_10049170": { "compartment": "compartment_876", "id": "reaction_10049170", "reactome": "R-BTA-429749", "name": "SLC5A8 transports monocarboxylates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429739", "species_74113" ], "products": [ "species_83910", "species_429748" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_76179", "species_2022890", "CHEBI:30768", "species_76179", "species_113557", "species_2022890", "species_373863", "CHEBI:30768", "species_197230", "ENSBTAT00000015315" ] }, "reaction_10085352": { "compartment": "compartment_70101", "id": "reaction_10085352", "reactome": "R-BTA-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10085359": { "compartment": "compartment_70101", "id": "reaction_10085359", "reactome": "R-BTA-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10042915": { "compartment": "compartment_7660", "id": "reaction_10042915", "reactome": "R-BTA-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200492", "species_29358" ], "products": [ "species_8878981", "species_200499" ], "modifiers": [ [ "species_10042912", "catalyst" ] ], "additional_components": [ "Q0VD50", "ENSBTAT00000082151", "species_29426" ] }, "reaction_10041831": { "compartment": "compartment_70101", "id": "reaction_10041831", "reactome": "R-BTA-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_70106", "species_197238" ], "products": [ "species_111294", "species_113528", "species_197220" ], "modifiers": [ [ "species_10041828", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083204" ] }, "reaction_10086630": { "compartment": "compartment_984", "id": "reaction_10086630", "reactome": "R-BTA-8938076", "name": "CD38 hydrolyses NAD+ to NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10086627", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073897" ] }, "reaction_10053298": { "compartment": "compartment_70101", "id": "reaction_10053298", "reactome": "R-BTA-947531", "name": "Molybdenum ion transfer onto molybdopterin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947561", "species_947496" ], "products": [ "species_111294", "species_947539", "species_76577" ], "modifiers": [ [ "species_10053295", "catalyst" ] ], "additional_components": [ "A0A3Q1ME13", "ENSBTAT00000081310", "species_29926" ] }, "reaction_10053266": { "compartment": "compartment_70101", "id": "reaction_10053266", "reactome": "R-BTA-947499", "name": "Exchange of oxygen with sulfur in MoCo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947539", "species_111707" ], "products": [ "species_947575", "species_29432" ], "modifiers": [ [ "species_10053263", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065375" ] }, "reaction_10053287": { "compartment": "compartment_70101", "id": "reaction_10053287", "reactome": "R-BTA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10053272" ], "products": [ "species_29432", "species_10053277" ], "modifiers": [ [ "species_10053284", "catalyst" ] ], "additional_components": [ "species_29426", "A1A4L8", "ENSBTAT00000070167", "A1A4L8", "ENSBTAT00000070167", "species_29426", "A5PKG4", "ENSBTAT00000009149" ] }, "reaction_10053352": { "compartment": "compartment_70101", "id": "reaction_10053352", "reactome": "R-BTA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10066619": { "compartment": "compartment_70101", "id": "reaction_10066619", "reactome": "R-BTA-3204311", "name": "AOX1 oxidises PXL to PDXate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965131" ], "products": [ "species_3204324", "species_29408" ], "modifiers": [ [ "species_10066616", "catalyst" ] ], "additional_components": [ "CHEBI:33722", "CHEBI:44074", "species_113596", "A0A3Q1LJG6", "ENSBTAT00000075745" ] }, "reaction_10053361": { "compartment": "compartment_70101", "id": "reaction_10053361", "reactome": "R-BTA-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_964952" ], "products": [ "species_29390", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053363": { "compartment": "compartment_70101", "id": "reaction_10053363", "reactome": "R-BTA-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965146" ], "products": [ "species_29390", "species_31633", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053348": { "compartment": "compartment_70101", "id": "reaction_10053348", "reactome": "R-BTA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10053350": { "compartment": "compartment_70101", "id": "reaction_10053350", "reactome": "R-BTA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10041753": { "compartment": "compartment_70101", "id": "reaction_10041753", "reactome": "R-BTA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10041750", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LMH4", "ENSBTAT00000085465" ] }, "reaction_10042799": { "compartment": "compartment_876", "id": "reaction_10042799", "reactome": "R-BTA-199626", "name": "SLC19A2/3 transport extracellular THMN to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199622" ], "products": [ "species_196934" ], "modifiers": [ [ "species_10042796", "catalyst" ] ], "additional_components": [ "A7E352", "ENSBTAT00000084175", "E1BLU2", "ENSBTAT00000027006" ] }, "reaction_10066585": { "compartment": "compartment_5460", "id": "reaction_10066585", "reactome": "R-BTA-3159253", "name": "MMAB transfers adenosyl group from ATP to cob(I)alamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3159260", "species_113593" ], "products": [ "species_3159274", "species_3159297" ], "modifiers": [ [ "species_10066582", "catalyst" ] ], "additional_components": [ "A0A3Q1NBS4", "ENSBTAT00000056628" ] }, "reaction_10066587": { "compartment": "compartment_5460", "id": "reaction_10066587", "reactome": "R-BTA-3159259", "name": "MMAA:MUT binds AdoCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033882", "species_3159297" ], "products": [ "species_10033884" ], "modifiers": [], "additional_components": [ "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806", "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10066458": { "compartment": "compartment_984", "id": "reaction_10066458", "reactome": "R-BTA-3000120", "name": "GIF binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066454", "species_3000125" ], "products": [ "species_10066456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066461": { "compartment": "compartment_984", "id": "reaction_10066461", "reactome": "R-BTA-3000122", "name": "CD320 transports extracellular TCII:Cbl to endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066428", "species_10066440" ], "products": [ "species_10066438" ], "modifiers": [ [ "species_10066440", "catalyst" ] ], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777", "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10076254": { "compartment": "compartment_984", "id": "reaction_10076254", "reactome": "R-BTA-5693319", "name": "CTRC hydrolyses PRSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10076243" ], "products": [ "species_10076247", "species_10076245" ], "modifiers": [ [ "species_10076251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000071882" ] }, "reaction_10066526": { "compartment": "compartment_984", "id": "reaction_10066526", "reactome": "R-BTA-3132753", "name": "Pancreatic proteases degrade TCN1:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066519" ], "products": [ "species_3000125" ], "modifiers": [ [ "species_10066523", "catalyst" ] ], "additional_components": [ "species_3000241", "E1BCU6", "ENSBTAT00000027423", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10066430": { "compartment": "compartment_984", "id": "reaction_10066430", "reactome": "R-BTA-3000074", "name": "TCII binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066426", "species_3000125" ], "products": [ "species_10066428" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066576": { "compartment": "compartment_70101", "id": "reaction_10066576", "reactome": "R-BTA-3149563", "name": "MMADHC targets transport of cytosolic cob(II)alamin to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149564" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066450": { "compartment": "compartment_17940", "id": "reaction_10066450", "reactome": "R-BTA-3000112", "name": "Endosomal TCII:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066442" ], "products": [ "species_10066448" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066569": { "compartment": "compartment_70101", "id": "reaction_10066569", "reactome": "R-BTA-3149492", "name": "cob(II)alamin dissociates from MMACHC:MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066473": { "compartment": "compartment_161320", "id": "reaction_10066473", "reactome": "R-BTA-3000263", "name": "TCII:Cbl is degraded to release Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066448" ], "products": [ "species_3000239" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066571": { "compartment": "compartment_70101", "id": "reaction_10066571", "reactome": "R-BTA-3149494", "name": "MMACHC:cob(II)alamin binds MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066563", "species_10066499" ], "products": [ "species_10066565" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638" ] }, "reaction_10066444": { "compartment": "compartment_74700", "id": "reaction_10066444", "reactome": "R-BTA-3000109", "name": "CD320:TCII:Cbl dissociates into CD320 and TCII:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066438" ], "products": [ "species_10066442", "species_10066440" ], "modifiers": [], "additional_components": [ "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10066574": { "compartment": "compartment_70101", "id": "reaction_10066574", "reactome": "R-BTA-3149519", "name": "MMACHC decyanates CNCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10066497", "species_29364", "species_3149505" ], "products": [ "species_10066499", "species_29366", "species_1130611" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10066528": { "compartment": "compartment_984", "id": "reaction_10066528", "reactome": "R-BTA-3132759", "name": "TCN1 binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3132775" ], "products": [ "species_10066519", "species_3132772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066882": { "compartment": "compartment_984", "id": "reaction_10066882", "reactome": "R-BTA-3245898", "name": "TCN1 binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3000125" ], "products": [ "species_10066519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066471": { "compartment": "compartment_17940", "id": "reaction_10066471", "reactome": "R-BTA-3000247", "name": "Endosomal GIF:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066469" ], "products": [ "species_10066465" ], "modifiers": [], "additional_components": [ "species_3000241", "E1BCN2", "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066502": { "compartment": "compartment_70101", "id": "reaction_10066502", "reactome": "R-BTA-3095889", "name": "MMACHC reduces Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000241", "species_70106", "species_10066497", "species_29364" ], "products": [ "species_10066499", "species_29366" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10042648": { "compartment": "compartment_876", "id": "reaction_10042648", "reactome": "R-BTA-199206", "name": "SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199192", "species_74113" ], "products": [ "species_83910", "species_196820" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10041737": { "compartment": "compartment_70101", "id": "reaction_10041737", "reactome": "R-BTA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10041734", "catalyst" ] ], "additional_components": [ "A0A3S5ZP75", "ENSBTAT00000017259" ] }, "reaction_10041756": { "compartment": "compartment_70101", "id": "reaction_10041756", "reactome": "R-BTA-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_29370", "species_76194" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10042655": { "compartment": "compartment_70616", "id": "reaction_10042655", "reactome": "R-BTA-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10042652", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031344" ] }, "reaction_10041744": { "compartment": "compartment_70101", "id": "reaction_10041744", "reactome": "R-BTA-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_111294", "species_196778" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10041765": { "compartment": "compartment_70101", "id": "reaction_10041765", "reactome": "R-BTA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10041762", "catalyst" ] ], "additional_components": [ "species_73524", "A0A3Q1MNK4", "ENSBTAT00000076608" ] }, "reaction_10053048": { "compartment": "compartment_70101", "id": "reaction_10053048", "reactome": "R-BTA-933533", "name": "Dimerization of p-IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039550" ], "products": [ "species_10039554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053046": { "compartment": "compartment_13231", "id": "reaction_10053046", "reactome": "R-BTA-933531", "name": "Translocation of p-IRF7:p-IRF7 to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10037203": { "compartment": "compartment_7660", "id": "reaction_10037203", "reactome": "R-BTA-113402", "name": "Formation of DSIF:NELF:early elongation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037126", "species_10037171", "species_30595" ], "products": [ "species_10037173", "species_30595" ], "modifiers": [], "additional_components": [ "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "species_110614", "species_113592", "species_29494", "species_29438", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "species_110614", "species_113592", "species_29494", "species_29438" ] }, "reaction_10037205": { "compartment": "compartment_7660", "id": "reaction_10037205", "reactome": "R-BTA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037169", "species_10037137" ], "products": [ "species_10037171" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412" ] }, "reaction_10086136": { "compartment": "compartment_13946", "id": "reaction_10086136", "reactome": "R-BTA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086105" ], "products": [ "species_29420", "species_10086115", "species_10085883" ], "modifiers": [ [ "species_10086133", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N5L8", "ENSBTAT00000086931", "A0A3Q1MK52", "ENSBTAT00000082010", "F1MXL8", "ENSBTAT00000009769" ] }, "reaction_10085932": { "compartment": "compartment_437051", "id": "reaction_10085932", "reactome": "R-BTA-8876188", "name": "DENND4s exchange GTP for GDP on RAB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085911", "species_29438" ], "products": [ "species_29420", "species_10085915", "species_10085883" ], "modifiers": [ [ "species_10085929", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QLS9", "ENSBTAT00000001303", "species_29420", "A6QLS9", "ENSBTAT00000001303", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BJE1", "ENSBTAT00000022733", "F1N377", "ENSBTAT00000034026", "A0A3Q1NBE4", "ENSBTAT00000073212" ] }, "reaction_10086097": { "compartment": "compartment_171062", "id": "reaction_10086097", "reactome": "R-BTA-8877311", "name": "RAB31 GEFs exchange GTP for GDP on RAB31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086086", "species_29438" ], "products": [ "species_29420", "species_10086090", "species_10085883" ], "modifiers": [ [ "species_10086094", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29420", "Q08DC2", "ENSBTAT00000075871", "Q08DC2", "ENSBTAT00000075871", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000013748" ] }, "reaction_10086209": { "compartment": "compartment_20699", "id": "reaction_10086209", "reactome": "R-BTA-8877813", "name": "DENND5A,B exchange GTP for GDP on RAB39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086188" ], "products": [ "species_10086196", "species_29420", "species_10085883" ], "modifiers": [ [ "species_10086206", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "G3X7D3", "ENSBTAT00000024288", "species_29420", "G3X7D3", "ENSBTAT00000024288", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MUN3", "ENSBTAT00000069720", "F1MQ87", "ENSBTAT00000027075" ] }, "reaction_10086019": { "compartment": "compartment_70101", "id": "reaction_10086019", "reactome": "R-BTA-8876616", "name": "DENND6A,B exchange GTP for GDP on RAB14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086008" ], "products": [ "species_29420", "species_10086012", "species_10085883" ], "modifiers": [ [ "species_10086016", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3ZBG1", "ENSBTAT00000023671", "species_29420", "Q3ZBG1", "ENSBTAT00000023671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000067401" ] }, "reaction_10085988": { "compartment": "compartment_262783", "id": "reaction_10085988", "reactome": "R-BTA-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10085979" ], "products": [ "species_29420", "species_10085983", "species_10085883" ], "modifiers": [ [ "species_10085985", "catalyst" ] ], "additional_components": [ "species_29420", "A6QPX8", "ENSBTAT00000013671", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QPX8", "ENSBTAT00000013671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MCL3", "ENSBTAT00000087265" ] }, "reaction_10086054": { "compartment": "compartment_171062", "id": "reaction_10086054", "reactome": "R-BTA-8876837", "name": "RAB21 GEFs exchange GTP for GDP on RAB21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086037" ], "products": [ "species_29420", "species_10085883", "species_10086041" ], "modifiers": [ [ "species_10086051", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "F1MPP1", "ENSBTAT00000025807", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29438", "F1MPP1", "ENSBTAT00000025807", "A0A3Q1M4Y7", "ENSBTAT00000075635", "A0A3Q1M373", "ENSBTAT00000078087" ] }, "reaction_10086182": { "compartment": "compartment_5668575", "id": "reaction_10086182", "reactome": "R-BTA-8877760", "name": "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086161" ], "products": [ "species_29420", "species_10085883", "species_10086169" ], "modifiers": [ [ "species_10086179", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29438", "E1B7M9", "ENSBTAT00000056415", "A0A3Q1N720", "ENSBTAT00000071404" ] }, "reaction_10048567": { "compartment": "compartment_876", "id": "reaction_10048567", "reactome": "R-BTA-425994", "name": "Na+/H+ exchanger transport (at cell membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10048564", "catalyst" ] ], "additional_components": [ "E1BB11", "ENSBTAT00000002235", "F1MU00", "ENSBTAT00000006073", "E1B8Y0", "ENSBTAT00000054801" ] }, "reaction_10048550": { "compartment": "compartment_171062", "id": "reaction_10048550", "reactome": "R-BTA-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10048547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073706" ] }, "reaction_10058841": { "compartment": "compartment_12045", "id": "reaction_10058841", "reactome": "R-BTA-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10059000": { "compartment": "compartment_12045", "id": "reaction_10059000", "reactome": "R-BTA-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10059851": { "compartment": "compartment_984", "id": "reaction_10059851", "reactome": "R-BTA-1602377", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_426658" ], "products": [ "species_1602420", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058874": { "compartment": "compartment_12045", "id": "reaction_10058874", "reactome": "R-BTA-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10058975": { "compartment": "compartment_12045", "id": "reaction_10058975", "reactome": "R-BTA-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058972", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059026": { "compartment": "compartment_12045", "id": "reaction_10059026", "reactome": "R-BTA-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10059023", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576" ] }, "reaction_10048682": { "compartment": "compartment_7660", "id": "reaction_10048682", "reactome": "R-BTA-427337", "name": "MBD2 binds methylcytosine in chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035250", "species_10035235" ], "products": [ "species_10035252" ], "modifiers": [], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000053498", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10048717": { "compartment": "compartment_7660", "id": "reaction_10048717", "reactome": "R-BTA-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048700", "species_427523" ], "products": [ "species_427497", "species_10044309", "species_427498" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10048720": { "compartment": "compartment_7660", "id": "reaction_10048720", "reactome": "R-BTA-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044309" ], "products": [ "species_77502", "species_10048712" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10044361": { "compartment": "compartment_7660", "id": "reaction_10044361", "reactome": "R-BTA-212252", "name": "Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044357", "species_10044309" ], "products": [ "species_10044359" ], "modifiers": [], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044381": { "compartment": "compartment_7660", "id": "reaction_10044381", "reactome": "R-BTA-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044359" ], "products": [ "species_77502", "species_10044378" ], "modifiers": [ [ "species_10044359", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044333": { "compartment": "compartment_7660", "id": "reaction_10044333", "reactome": "R-BTA-212222", "name": "PRC2 recruits DNA methyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044307", "species_10044329" ], "products": [ "species_10044331" ], "modifiers": [], "additional_components": [ "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10044390": { "compartment": "compartment_7660", "id": "reaction_10044390", "reactome": "R-BTA-212269", "name": "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044331" ], "products": [ "species_77502", "species_10044387" ], "modifiers": [ [ "species_10044331", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10070700": { "compartment": "compartment_7660", "id": "reaction_10070700", "reactome": "R-BTA-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10036698" ], "products": [ "species_10036706", "species_5221065" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10070702": { "compartment": "compartment_7660", "id": "reaction_10070702", "reactome": "R-BTA-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10036698" ], "products": [ "species_10036706", "species_5221064" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10071065": { "compartment": "compartment_7660", "id": "reaction_10071065", "reactome": "R-BTA-5250938", "name": "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10035231" ], "products": [ "species_2485002", "species_10071014" ], "modifiers": [ [ "species_10071062", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "E1BP59", "ENSBTAT00000061193", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "A5PJQ1", "ENSBTAT00000017097", "E1B6X6", "ENSBTAT00000072070", "E1BKX3", "ENSBTAT00000009771", "F1MX61", "ENSBTAT00000011734", "A0A3Q1M384", "ENSBTAT00000070441", "F6QHI8", "ENSBTAT00000019351", "Q1JQD6", "ENSBTAT00000043676", "Q32LB6", "ENSBTAT00000004611", "F1MUD5", "ENSBTAT00000056158" ] }, "reaction_10065336": { "compartment": "compartment_984", "id": "reaction_10065336", "reactome": "R-BTA-2395328", "name": "LTBP1, LTBP3 bind TGF-Beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065332", "species_10065308" ], "products": [ "species_10065334" ], "modifiers": [], "additional_components": [ "A6QP91", "ENSBTAT00000015925", "ENSBTAT00000075583", "A0A3Q1LJU9", "ENSBTAT00000075583", "A6QP91", "ENSBTAT00000015925" ] }, "reaction_10065435": { "compartment": "compartment_984", "id": "reaction_10065435", "reactome": "R-BTA-2396399", "name": "Fibrillins bind BMPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065431", "species_10063837" ], "products": [ "species_10065433" ], "modifiers": [], "additional_components": [ "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807", "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807" ] }, "reaction_10064435": { "compartment": "compartment_984", "id": "reaction_10064435", "reactome": "R-BTA-2161282", "name": "Elastic fibres bind associated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064421", "species_10064431" ], "products": [ "species_10064433" ], "modifiers": [], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049" ] }, "reaction_10063839": { "compartment": "compartment_984", "id": "reaction_10063839", "reactome": "R-BTA-2129362", "name": "Fibrillin microfibril assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063825" ], "products": [ "species_10063837" ], "modifiers": [], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360" ] }, "reaction_10064437": { "compartment": "compartment_984", "id": "reaction_10064437", "reactome": "R-BTA-2161293", "name": "Tropoelastin forms aggregate globules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059655" ], "products": [ "species_10063809" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399" ] }, "reaction_10067346": { "compartment": "compartment_70101", "id": "reaction_10067346", "reactome": "R-BTA-3295580", "name": "TRPM4,5 transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10067343", "catalyst" ] ], "additional_components": [ "E1BNX9", "ENSBTAT00000008077", "A0A3Q1M0Y5", "ENSBTAT00000075032" ] }, "reaction_10092050": { "compartment": "compartment_70101", "id": "reaction_10092050", "reactome": "R-BTA-9701055", "name": "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10092047", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G5E522", "ENSBTAT00000002668", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10067332": { "compartment": "compartment_70101", "id": "reaction_10067332", "reactome": "R-BTA-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10067306", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G3MY82", "ENSBTAT00000065500", "E1BPC8", "ENSBTAT00000019509", "G3N2S2", "ENSBTAT00000066065", "Q5EA32", "ENSBTAT00000003922", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LTG6", "ENSBTAT00000070979", "F1MPF0", "ENSBTAT00000044081", "P79100", "ENSBTAT00000065392", "E1BAN3", "ENSBTAT00000033438", "F1N232", "ENSBTAT00000068680", "A0A3Q1M4W2", "ENSBTAT00000077611", "E1BDG0", "ENSBTAT00000022589", "E1BCP0", "ENSBTAT00000085000", "G5E522", "ENSBTAT00000002668", "E1B6Y9", "ENSBTAT00000002485", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10039604": { "compartment": "compartment_70616", "id": "reaction_10039604", "reactome": "R-BTA-170026", "name": "Protons are translocated from the intermembrane space to the matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953" ], "products": [ "species_113529" ], "modifiers": [ [ "species_10039233", "catalyst" ], [ "species_30495", "catalyst" ], [ "species_170037", "inhibitor" ] ], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_113592", "species_29370", "species_29420", "species_29438" ] }, "reaction_10039240": { "compartment": "compartment_70616", "id": "reaction_10039240", "reactome": "R-BTA-166214", "name": "FA anion flip-flops to the opposite surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039235" ], "products": [ "species_10039237" ], "modifiers": [ [ "species_10039235", "catalyst" ] ], "additional_components": [ "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039242": { "compartment": "compartment_70616", "id": "reaction_10039242", "reactome": "R-BTA-166220", "name": "FA anion diffuses laterally to UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039233", "species_166213" ], "products": [ "species_10039235" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039254": { "compartment": "compartment_70616", "id": "reaction_10039254", "reactome": "R-BTA-166387", "name": "The FA anion diffuses away laterally from UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039237" ], "products": [ "species_166216", "species_10039233" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10073400": { "compartment": "compartment_7660", "id": "reaction_10073400", "reactome": "R-BTA-5661122", "name": "JMJD6 demethylates Me2R3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073398", "species_113671", "species_113685" ], "products": [ "species_10066894", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10066651": { "compartment": "compartment_7660", "id": "reaction_10066651", "reactome": "R-BTA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066642" ], "products": [ "species_10066644", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10073402": { "compartment": "compartment_7660", "id": "reaction_10073402", "reactome": "R-BTA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069756" ], "products": [ "species_10066642", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10069754": { "compartment": "compartment_7660", "id": "reaction_10069754", "reactome": "R-BTA-4754176", "name": "JMJD6 demethylates MeR3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066894", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10073404": { "compartment": "compartment_7660", "id": "reaction_10073404", "reactome": "R-BTA-5661124", "name": "JMJD6 demethylates MeR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070273", "species_113671", "species_113685" ], "products": [ "species_10035060", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000025492" ] }, "reaction_10073406": { "compartment": "compartment_7660", "id": "reaction_10073406", "reactome": "R-BTA-5661125", "name": "JMJD6 demethylates Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_113671", "species_113685" ], "products": [ "species_10070273", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000025492" ] }, "reaction_10069747": { "compartment": "compartment_7660", "id": "reaction_10069747", "reactome": "R-BTA-4724284", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069723" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10073394": { "compartment": "compartment_7660", "id": "reaction_10073394", "reactome": "R-BTA-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069811", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069721" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073396": { "compartment": "compartment_7660", "id": "reaction_10073396", "reactome": "R-BTA-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10072792" ], "products": [ "species_10069777", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10069719": { "compartment": "compartment_7660", "id": "reaction_10069719", "reactome": "R-BTA-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069712", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069769": { "compartment": "compartment_7660", "id": "reaction_10069769", "reactome": "R-BTA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10069756", "species_113685" ], "products": [ "species_10066642", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10073384": { "compartment": "compartment_7660", "id": "reaction_10073384", "reactome": "R-BTA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070949", "species_113671", "species_113685" ], "products": [ "species_29478", "species_10069756", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10069740": { "compartment": "compartment_7660", "id": "reaction_10069740", "reactome": "R-BTA-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073380": { "compartment": "compartment_7660", "id": "reaction_10073380", "reactome": "R-BTA-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10072735", "species_113685" ], "products": [ "species_10069712", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069796": { "compartment": "compartment_7660", "id": "reaction_10069796", "reactome": "R-BTA-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069777", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069785" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10073382": { "compartment": "compartment_7660", "id": "reaction_10073382", "reactome": "R-BTA-5661115", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10069937": { "compartment": "compartment_7660", "id": "reaction_10069937", "reactome": "R-BTA-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10066642" ], "modifiers": [ [ "species_10069934", "catalyst" ] ], "additional_components": [ "F1MUT0", "ENSBTAT00000004658", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072752": { "compartment": "compartment_7660", "id": "reaction_10072752", "reactome": "R-BTA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069712" ], "products": [ "species_77502", "species_10072735" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072755": { "compartment": "compartment_7660", "id": "reaction_10072755", "reactome": "R-BTA-5638332", "name": "PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069785" ], "modifiers": [ [ "species_10044337", "catalyst" ] ], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10069939": { "compartment": "compartment_7660", "id": "reaction_10069939", "reactome": "R-BTA-5159250", "name": "ATF7IP binds SETDB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069830", "species_10069834" ], "products": [ "species_10069836" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000107", "ENSBTAT00000086218", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10070962": { "compartment": "compartment_7660", "id": "reaction_10070962", "reactome": "R-BTA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069756" ], "products": [ "species_77502", "species_10070949" ], "modifiers": [ [ "species_10070959", "catalyst" ], [ "species_10070404", "inhibitor" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "G3X834", "ENSBTAT00000056084", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072725": { "compartment": "compartment_7660", "id": "reaction_10072725", "reactome": "R-BTA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066642" ], "products": [ "species_77502", "species_10069756" ], "modifiers": [ [ "species_10072722", "catalyst" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072788": { "compartment": "compartment_7660", "id": "reaction_10072788", "reactome": "R-BTA-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072771" ], "products": [ "species_77502", "species_10072786" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072823": { "compartment": "compartment_7660", "id": "reaction_10072823", "reactome": "R-BTA-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072800" ], "products": [ "species_77502", "species_10072821" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10069846": { "compartment": "compartment_7660", "id": "reaction_10069846", "reactome": "R-BTA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069712" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072790": { "compartment": "compartment_7660", "id": "reaction_10072790", "reactome": "R-BTA-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10072763" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072778": { "compartment": "compartment_7660", "id": "reaction_10072778", "reactome": "R-BTA-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072763" ], "products": [ "species_77502", "species_10072771" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072813": { "compartment": "compartment_7660", "id": "reaction_10072813", "reactome": "R-BTA-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10064889" ], "products": [ "species_77502", "species_10072800" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10072655": { "compartment": "compartment_70101", "id": "reaction_10072655", "reactome": "R-BTA-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10072636" ], "products": [ "species_10072642", "species_71285" ], "modifiers": [ [ "species_10072652", "catalyst" ] ], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "F1MTF1", "ENSBTAT00000025245" ] }, "reaction_10069838": { "compartment": "compartment_7660", "id": "reaction_10069838", "reactome": "R-BTA-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069721" ], "products": [ "species_77502", "species_10069811" ], "modifiers": [ [ "species_10069825", "catalyst" ], [ "species_10069836", "catalyst" ] ], "additional_components": [ "F1N6Y5", "ENSBTAT00000022553", "F1MXG0", "ENSBTAT00000009641", "A0A452DJ38", "ENSBTAT00000013472", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10072750": { "compartment": "compartment_7660", "id": "reaction_10072750", "reactome": "R-BTA-5638141", "name": "SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072735" ], "products": [ "species_77502", "species_10072743" ], "modifiers": [ [ "species_10072747", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084416" ] }, "reaction_10068699": { "compartment": "compartment_7660", "id": "reaction_10068699", "reactome": "R-BTA-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068694", "catalyst" ], [ "species_10068697", "inhibitor" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068844": { "compartment": "compartment_7660", "id": "reaction_10068844", "reactome": "R-BTA-3782637", "name": "HDAC8 deacetylates histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10044720", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000070733" ] }, "reaction_10091745": { "compartment": "compartment_7660", "id": "reaction_10091745", "reactome": "R-BTA-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068694", "species_9679795" ], "products": [ "species_10068697" ], "modifiers": [], "additional_components": [ "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068725": { "compartment": "compartment_7660", "id": "reaction_10068725", "reactome": "R-BTA-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068722", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "CHEBI:57627", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1MPA7", "ENSBTAT00000013888", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10068569": { "compartment": "compartment_7660", "id": "reaction_10068569", "reactome": "R-BTA-3662335", "name": "EP300 acetylates histone H2A, H2B, H3, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068132", "species_113560" ], "products": [ "species_2485002", "species_10068566" ], "modifiers": [ [ "species_10053052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021556" ] }, "reaction_10067596": { "compartment": "compartment_7660", "id": "reaction_10067596", "reactome": "R-BTA-3321883", "name": "MSL acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035060", "species_113560" ], "products": [ "species_2485002", "species_10067575" ], "modifiers": [ [ "species_10067593", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "F1MP98", "ENSBTAT00000013893", "F1MRF9", "ENSBTAT00000000991", "E1BFW0", "ENSBTAT00000030541" ] }, "reaction_10071886": { "compartment": "compartment_7660", "id": "reaction_10071886", "reactome": "R-BTA-5579018", "name": "NCOA1(868-1441) binds PAX3(1-319)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071878", "species_10071882" ], "products": [ "species_10071884" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064008", "ENSBTAT00000013131", "F1MTX0", "ENSBTAT00000013131", "G3N0C2", "ENSBTAT00000064008" ] }, "reaction_10070409": { "compartment": "compartment_7660", "id": "reaction_10070409", "reactome": "R-BTA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070394" ], "products": [ "species_77502", "species_10070404" ], "modifiers": [ [ "species_10070406", "catalyst" ] ], "additional_components": [ "A0A3Q1LQR4", "ENSBTAT00000066577", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070377": { "compartment": "compartment_7660", "id": "reaction_10070377", "reactome": "R-BTA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070328" ], "products": [ "species_77502", "species_10070374" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070520": { "compartment": "compartment_7660", "id": "reaction_10070520", "reactome": "R-BTA-5212679", "name": "DNMT3A binds Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_10044297" ], "products": [ "species_10070518" ], "modifiers": [], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000086443", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717" ] }, "reaction_10073416": { "compartment": "compartment_7660", "id": "reaction_10073416", "reactome": "R-BTA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070273" ], "products": [ "species_77502", "species_10073414" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070392": { "compartment": "compartment_7660", "id": "reaction_10070392", "reactome": "R-BTA-5205822", "name": "CARM1 methylates arginine-18 (H3R17) of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070379" ], "products": [ "species_77502", "species_10070389" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070282": { "compartment": "compartment_7660", "id": "reaction_10070282", "reactome": "R-BTA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10035060" ], "products": [ "species_77502", "species_10070273" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070896": { "compartment": "compartment_7660", "id": "reaction_10070896", "reactome": "R-BTA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070848" ], "products": [ "species_77502", "species_10070894" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070757": { "compartment": "compartment_7660", "id": "reaction_10070757", "reactome": "R-BTA-5229010", "name": "CARM1 methylates arginine-27 of histone H3 (H3R26)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070745" ], "products": [ "species_77502", "species_10070755" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070516": { "compartment": "compartment_7660", "id": "reaction_10070516", "reactome": "R-BTA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070467" ], "products": [ "species_77502", "species_10070513" ], "modifiers": [ [ "species_10066655", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068896" ] }, "reaction_10056383": { "compartment": "compartment_70101", "id": "reaction_10056383", "reactome": "R-BTA-1183128", "name": "PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1183111" ], "products": [ "species_29382", "species_1183191" ], "modifiers": [ [ "species_10056380", "catalyst" ] ], "additional_components": [ "species_74016", "A6QLC1", "ENSBTAT00000015977", "F1N048", "ENSBTAT00000004411", "E1BD46", "ENSBTAT00000015978", "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10066966": { "compartment": "compartment_7660", "id": "reaction_10066966", "reactome": "R-BTA-3247569", "name": "PADI4 deiminates Histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066920" ], "products": [ "species_10066951", "species_76230" ], "modifiers": [ [ "species_10066963", "catalyst" ] ], "additional_components": [ "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10092108": { "compartment": "compartment_24337", "id": "reaction_10092108", "reactome": "R-BTA-9705738", "name": "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092095", "species_10092091" ], "products": [ "species_10051733", "species_10055212", "species_10055148", "species_10055146", "species_10055162", "species_10092105" ], "modifiers": [ [ "species_10092091", "catalyst" ] ], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "ENSBTAT00000002831", "ENSBTAT00000026036", "ENSBTAT00000078734", "ENSBTAT00000068692", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831" ] }, "reaction_10092257": { "compartment": "compartment_24337", "id": "reaction_10092257", "reactome": "R-BTA-9707977", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092105" ], "products": [ "species_10092255" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10073690": { "compartment": "compartment_876", "id": "reaction_10073690", "reactome": "R-BTA-5668414", "name": "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10073673" ], "products": [ "species_10073687" ], "modifiers": [ [ "species_10073673", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074280": { "compartment": "compartment_876", "id": "reaction_10074280", "reactome": "R-BTA-5675948", "name": "TNFRSF6B binds TNFSF6,14,15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074276", "species_10074270" ], "products": [ "species_10074278" ], "modifiers": [], "additional_components": [ "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452", "ENSBTAT00000028109", "A6QPW7", "ENSBTAT00000028109", "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10074266": { "compartment": "compartment_876", "id": "reaction_10074266", "reactome": "R-BTA-5675947", "name": "TNFSF18 binds TNFRSF18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074262", "species_10074258" ], "products": [ "species_10074264" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064406", "ENSBTAT00000079425", "A0A3Q1M9X1", "ENSBTAT00000079425", "Q08DT5", "ENSBTAT00000064406" ] }, "reaction_10076237": { "compartment": "compartment_876", "id": "reaction_10076237", "reactome": "R-BTA-5693012", "name": "TNFSF15 binds TNFRSF25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074274", "species_10076233" ], "products": [ "species_10076235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036452", "ENSBTAT00000085571", "A0A3Q1LIC4", "ENSBTAT00000085571", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10073765": { "compartment": "compartment_876", "id": "reaction_10073765", "reactome": "R-BTA-5669035", "name": "TNFSF11 binds TNFRSF11A, B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073761" ], "products": [ "species_10073763" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009759", "A5D7R1", "ENSBTAT00000009759", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10076165": { "compartment": "compartment_876", "id": "reaction_10076165", "reactome": "R-BTA-5692315", "name": "OX40L binds OX40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076161", "species_10076155" ], "products": [ "species_10076163" ], "modifiers": [], "additional_components": [ "E1BGY4", "ENSBTAT00000003763", "ENSBTAT00000066801", "A0A3Q1M5M3", "ENSBTAT00000066801", "E1BGY4", "ENSBTAT00000003763" ] }, "reaction_10074340": { "compartment": "compartment_876", "id": "reaction_10074340", "reactome": "R-BTA-5676607", "name": "sBAFF,sAPRIL binds TACI,BCMA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074326", "species_10074336" ], "products": [ "species_10074338" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10074312": { "compartment": "compartment_876", "id": "reaction_10074312", "reactome": "R-BTA-5676593", "name": "TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073669", "species_10073585" ], "products": [ "species_10073671" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074314": { "compartment": "compartment_876", "id": "reaction_10074314", "reactome": "R-BTA-5676595", "name": "TRAFs bind RANK:RANKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073623", "species_10073585" ], "products": [ "species_10073625" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073757": { "compartment": "compartment_876", "id": "reaction_10073757", "reactome": "R-BTA-5669023", "name": "TWEAK binds FN14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073601", "species_10073597" ], "products": [ "species_10073603" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081383", "F1MX43", "ENSBTAT00000045584", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074316": { "compartment": "compartment_876", "id": "reaction_10074316", "reactome": "R-BTA-5676596", "name": "TRAF3 binds BAFFR:BAFF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073637", "species_10073585" ], "products": [ "species_10073639" ], "modifiers": [], "additional_components": [ "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074318": { "compartment": "compartment_876", "id": "reaction_10074318", "reactome": "R-BTA-5676598", "name": "TRAF2:cIAP1/2 complex binds FN14:TWEAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073603", "species_10073585" ], "products": [ "species_10073605" ], "modifiers": [], "additional_components": [ "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074320": { "compartment": "compartment_876", "id": "reaction_10074320", "reactome": "R-BTA-5676599", "name": "sBAFF trimer binds BAFFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073635", "species_10073629" ], "products": [ "species_10073637" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "ENSBTAT00000037660", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074306": { "compartment": "compartment_876", "id": "reaction_10074306", "reactome": "R-BTA-5676589", "name": "RANKL,sRANKL trimer binds RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073609" ], "products": [ "species_10074304" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10074308": { "compartment": "compartment_876", "id": "reaction_10074308", "reactome": "R-BTA-5676591", "name": "2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073667", "species_10073643" ], "products": [ "species_10073669" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "ENSBTAT00000020355", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074310": { "compartment": "compartment_876", "id": "reaction_10074310", "reactome": "R-BTA-5676592", "name": "2xRANK binds RANKL,sRANKL trimer:RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074304", "species_10073609" ], "products": [ "species_10073623" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073699": { "compartment": "compartment_876", "id": "reaction_10073699", "reactome": "R-BTA-5668454", "name": "K63polyUb-cIAP1,2 ubiquitinates TRAF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073687", "species_10052288" ], "products": [ "species_10073696" ], "modifiers": [ [ "species_10073687", "catalyst" ] ], "additional_components": [ "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10071948": { "compartment": "compartment_70101", "id": "reaction_10071948", "reactome": "R-BTA-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524" ], "products": [ "species_10047524" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10073708": { "compartment": "compartment_70101", "id": "reaction_10073708", "reactome": "R-BTA-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_29370", "species_10073705" ], "modifiers": [ [ "species_10047524", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10071982": { "compartment": "compartment_70101", "id": "reaction_10071982", "reactome": "R-BTA-5607726", "name": "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071979" ], "products": [ "species_29370", "species_10071971" ], "modifiers": [ [ "species_10071979", "catalyst" ] ], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316" ] }, "reaction_10072030": { "compartment": "compartment_7660", "id": "reaction_10072030", "reactome": "R-BTA-5607741", "name": "p52:RELB translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071991" ], "products": [ "species_10072028" ], "modifiers": [], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "F1MBB0", "ENSBTAT00000055496", "A7MBB7", "ENSBTAT00000007904" ] }, "reaction_10071975": { "compartment": "compartment_70101", "id": "reaction_10071975", "reactome": "R-BTA-5607723", "name": "SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10071971" ], "products": [ "species_10071973" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10057834": { "compartment": "compartment_70101", "id": "reaction_10057834", "reactome": "R-BTA-1370500", "name": "PRLR binds SCF beta-TrCP complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10054520" ], "products": [ "species_10054522" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10054524": { "compartment": "compartment_984", "id": "reaction_10054524", "reactome": "R-BTA-976991", "name": "Prolactin receptor ligands bind the prolactin receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054501", "species_10054509" ], "products": [ "species_10054511" ], "modifiers": [ [ "species_10054522", "inhibitor" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10060412": { "compartment": "compartment_876", "id": "reaction_10060412", "reactome": "R-BTA-1671687", "name": "PRLR activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054511" ], "products": [ "species_10054511" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10057836": { "compartment": "compartment_876", "id": "reaction_10057836", "reactome": "R-BTA-1370505", "name": "PRLR is phosphorylated at Ser-349", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054520" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057823": { "compartment": "compartment_876", "id": "reaction_10057823", "reactome": "R-BTA-1364044", "name": "PRLR:JAK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054507" ], "products": [ "species_10054509" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10056335": { "compartment": "compartment_876", "id": "reaction_10056335", "reactome": "R-BTA-1170539", "name": "Prolactin receptor is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054522" ], "products": [ "species_10043873", "species_10056333" ], "modifiers": [], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10054791": { "compartment": "compartment_876", "id": "reaction_10054791", "reactome": "R-BTA-982810", "name": "JAK2 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054785" ], "modifiers": [ [ "species_10054789", "catalyst" ] ], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10054779": { "compartment": "compartment_984", "id": "reaction_10054779", "reactome": "R-BTA-982765", "name": "Growth hormone forms dimers and oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048427" ], "products": [ "species_10054777" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082606", "A0A3Q1LZG1", "ENSBTAT00000082606" ] }, "reaction_10056268": { "compartment": "compartment_876", "id": "reaction_10056268", "reactome": "R-BTA-1169192", "name": "PTP1B dephosphorylates GHR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10056255" ], "products": [ "species_29372", "species_10056265" ], "modifiers": [ [ "species_10056255", "catalyst" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678", "A6QQN2", "ENSBTAT00000008678", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090844": { "compartment": "compartment_876", "id": "reaction_10090844", "reactome": "R-BTA-9604767", "name": "FLT3LG dimer:FLT3 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084303" ], "products": [ "species_29370", "species_10036552" ], "modifiers": [ [ "species_10084303", "catalyst" ], [ "species_10090842", "inhibitor" ], [ "species_10090840", "inhibitor" ] ], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092151": { "compartment": "compartment_876", "id": "reaction_10092151", "reactome": "R-BTA-9706336", "name": "Active FLT3 binds to SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10036552" ], "products": [ "species_10092149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10092159": { "compartment": "compartment_876", "id": "reaction_10092159", "reactome": "R-BTA-9706344", "name": "FLT3 phosphorylates GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092135", "species_113592" ], "products": [ "species_29370", "species_10092156" ], "modifiers": [ [ "species_10092135", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10077790": { "compartment": "compartment_876", "id": "reaction_10077790", "reactome": "R-BTA-6786789", "name": "FLT3LG dimer binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036540", "species_10077786" ], "products": [ "species_10077788" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10084305": { "compartment": "compartment_876", "id": "reaction_10084305", "reactome": "R-BTA-8854736", "name": "FLT3LG dimer:FLT3 binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077788", "species_10077786" ], "products": [ "species_10084303" ], "modifiers": [], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10092040": { "compartment": "compartment_876", "id": "reaction_10092040", "reactome": "R-BTA-9698408", "name": "PTPRJ dephosphorylates active FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036552" ], "products": [ "species_10092037", "species_29372" ], "modifiers": [ [ "species_10080697", "catalyst" ], [ "species_29408", "inhibitor" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "ENSBTAT00000081330" ] }, "reaction_10092139": { "compartment": "compartment_876", "id": "reaction_10092139", "reactome": "R-BTA-9706315", "name": "Active FLT3 binds to SH2B3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055924", "species_10036552" ], "products": [ "species_10092112" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079236", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092173": { "compartment": "compartment_876", "id": "reaction_10092173", "reactome": "R-BTA-9706350", "name": "FLT3 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10092110" ], "products": [ "species_29370", "species_10092170" ], "modifiers": [ [ "species_10092110", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092141": { "compartment": "compartment_876", "id": "reaction_10092141", "reactome": "R-BTA-9706319", "name": "Active FLT3 binds to SLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092116", "species_10036552" ], "products": [ "species_10092118" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400" ] }, "reaction_10092143": { "compartment": "compartment_876", "id": "reaction_10092143", "reactome": "R-BTA-9706323", "name": "Active FLT3 binds to SLA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092122", "species_10036552" ], "products": [ "species_10092124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137" ] }, "reaction_10092126": { "compartment": "compartment_876", "id": "reaction_10092126", "reactome": "R-BTA-9706293", "name": "Active FLT3 binds to CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10036552" ], "products": [ "species_10092110" ], "modifiers": [ [ "species_10092118", "catalyst" ], [ "species_10092124", "catalyst" ], [ "species_10092112", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092147": { "compartment": "compartment_876", "id": "reaction_10092147", "reactome": "R-BTA-9706330", "name": "Active FLT3 binds to SOCS6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087926", "species_10036552" ], "products": [ "species_10092145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023144", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKN8", "ENSBTAT00000023144" ] }, "reaction_10092195": { "compartment": "compartment_876", "id": "reaction_10092195", "reactome": "R-BTA-9706364", "name": "Internalization of ubiquitinated FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092178" ], "products": [ "species_10092193" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092183": { "compartment": "compartment_876", "id": "reaction_10092183", "reactome": "R-BTA-9706354", "name": "Ubiquitination of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10036552" ], "products": [ "species_10092178" ], "modifiers": [ [ "species_10092180", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092137": { "compartment": "compartment_876", "id": "reaction_10092137", "reactome": "R-BTA-9706308", "name": "Active FLT3 binds to GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10036552" ], "products": [ "species_10092135" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10092043": { "compartment": "compartment_70101", "id": "reaction_10092043", "reactome": "R-BTA-9699578", "name": "Active FLT3 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499", "species_113592" ], "products": [ "species_29370", "species_10083560" ], "modifiers": [ [ "species_10036552", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092033": { "compartment": "compartment_876", "id": "reaction_10092033", "reactome": "R-BTA-9698170", "name": "Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036565", "species_10035515" ], "products": [ "species_10065275" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10092133": { "compartment": "compartment_876", "id": "reaction_10092133", "reactome": "R-BTA-9706304", "name": "Active FLT3 binds to GRAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046947", "species_10036552" ], "products": [ "species_10092131" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020161", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKA6", "ENSBTAT00000020161" ] }, "reaction_10092165": { "compartment": "compartment_876", "id": "reaction_10092165", "reactome": "R-BTA-9706345", "name": "Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092161", "species_10035515" ], "products": [ "species_10092163" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "P32871", "ENSBTAT00000072391", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10090916": { "compartment": "compartment_70101", "id": "reaction_10090916", "reactome": "R-BTA-9607301", "name": "Active FLT3:GRB2 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10036554" ], "products": [ "species_10074033" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10090919": { "compartment": "compartment_70101", "id": "reaction_10090919", "reactome": "R-BTA-9607304", "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074033", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10052217": { "compartment": "compartment_70101", "id": "reaction_10052217", "reactome": "R-BTA-909726", "name": "Phosphorylation of STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052144", "species_113592", "species_10051758" ], "products": [ "species_10052194", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ], [ "species_10047046", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10052347": { "compartment": "compartment_13231", "id": "reaction_10052347", "reactome": "R-BTA-913529", "name": "Translocation of p-STAT1:p-STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10052189": { "compartment": "compartment_13231", "id": "reaction_10052189", "reactome": "R-BTA-909721", "name": "Translocation of ISGF3 complex to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052169" ], "products": [ "species_10052181" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "Q58DC4", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10055946": { "compartment": "compartment_70101", "id": "reaction_10055946", "reactome": "R-BTA-997309", "name": "Dephosphorylation of STAT1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052194" ], "products": [ "species_10055943", "species_29372" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000002653" ] }, "reaction_10055955": { "compartment": "compartment_70101", "id": "reaction_10055955", "reactome": "R-BTA-997311", "name": "Dephosphorylation of TYK2 by PTP1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052222" ], "products": [ "species_29372", "species_10055948" ], "modifiers": [ [ "species_10055952", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000008678" ] }, "reaction_10055958": { "compartment": "compartment_70101", "id": "reaction_10055958", "reactome": "R-BTA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10055948" ], "products": [ "species_29372", "species_10052206" ], "modifiers": [ [ "species_10043836", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000077529" ] }, "reaction_10052159": { "compartment": "compartment_70101", "id": "reaction_10052159", "reactome": "R-BTA-909719", "name": "Recruitment of STAT2 to p-IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052140", "species_10052153" ], "products": [ "species_10052157" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10070719": { "compartment": "compartment_5460", "id": "reaction_10070719", "reactome": "R-BTA-5223305", "name": "ABCE1 binds RNASEL, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070711", "species_10070715" ], "products": [ "species_10070717" ], "modifiers": [], "additional_components": [ "A5H027", "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10052147": { "compartment": "compartment_70101", "id": "reaction_10052147", "reactome": "R-BTA-909718", "name": "Formation of p-STAT1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051758" ], "products": [ "species_10051766", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052210": { "compartment": "compartment_876", "id": "reaction_10052210", "reactome": "R-BTA-909724", "name": "Recruitment of IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052204", "species_10052200" ], "products": [ "species_10052206" ], "modifiers": [ [ "species_10052208", "inhibitor" ] ], "additional_components": [ "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052213": { "compartment": "compartment_70101", "id": "reaction_10052213", "reactome": "R-BTA-909725", "name": "Interaction of IRF9 with p-STAT2:p-STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052167", "species_10052163" ], "products": [ "species_10052169" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10052233": { "compartment": "compartment_70101", "id": "reaction_10052233", "reactome": "R-BTA-909730", "name": "Phosphorylation of INFAR1 by TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052222" ], "products": [ "species_29370", "species_10052153" ], "modifiers": [ [ "species_10052222", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10091725": { "compartment": "compartment_70101", "id": "reaction_10091725", "reactome": "R-BTA-9678737", "name": "IFNAR1:TYK2 binds TYK2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678619", "species_10052200" ], "products": [ "species_10052208" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052236": { "compartment": "compartment_70101", "id": "reaction_10052236", "reactome": "R-BTA-909732", "name": "Phosphorylation of STAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052157" ], "products": [ "species_29370", "species_10052144" ], "modifiers": [ [ "species_10052157", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052229": { "compartment": "compartment_70101", "id": "reaction_10052229", "reactome": "R-BTA-909729", "name": "Activation of JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052206" ], "products": [ "species_29370", "species_10052222" ], "modifiers": [ [ "species_10052206", "catalyst" ], [ "species_10052227", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052196": { "compartment": "compartment_70101", "id": "reaction_10052196", "reactome": "R-BTA-909722", "name": "Release of p-STAT2:p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052194" ], "products": [ "species_10052167", "species_10052153" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10056297": { "compartment": "compartment_70101", "id": "reaction_10056297", "reactome": "R-BTA-1169405", "name": "ISGylation of protein phosphatase 1 beta (PP2CB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056293", "species_113592" ], "products": [ "species_111294", "species_10056295", "species_10056276", "species_10053116", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000050064", "O02741", "ENSBTAT00000019573", "O62830", "ENSBTAT00000050064", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056315": { "compartment": "compartment_70101", "id": "reaction_10056315", "reactome": "R-BTA-1169406", "name": "ISGylation of host proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056311", "species_113592" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_76577", "species_10056313" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056283": { "compartment": "compartment_70101", "id": "reaction_10056283", "reactome": "R-BTA-1169394", "name": "ISGylation of IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10039246" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056280", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000031869", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "Q4JF28", "ENSBTAT00000031869", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060730": { "compartment": "compartment_70101", "id": "reaction_10060730", "reactome": "R-BTA-1678842", "name": "Competitive inhibition of translation initiation by ISGylated 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060726", "species_10060706" ], "products": [ "species_10060724", "species_10060728" ], "modifiers": [], "additional_components": [ "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060732": { "compartment": "compartment_70101", "id": "reaction_10060732", "reactome": "R-BTA-1678843", "name": "ISGylation of protein translation regulator 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10060704" ], "products": [ "species_10060706" ], "modifiers": [], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056287": { "compartment": "compartment_70101", "id": "reaction_10056287", "reactome": "R-BTA-1169402", "name": "ISGylation of E2 conjugating enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10055358" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056285", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000084854", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A3Q1MAR8", "ENSBTAT00000084854", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056289": { "compartment": "compartment_70101", "id": "reaction_10056289", "reactome": "R-BTA-1169403", "name": "Interaction of E3 ligase with ISG15:E2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056276", "species_10056270" ], "products": [ "species_10056278" ], "modifiers": [], "additional_components": [ "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060694": { "compartment": "compartment_70101", "id": "reaction_10060694", "reactome": "R-BTA-1678841", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056313" ], "products": [ "species_10056311", "species_141681" ], "modifiers": [ [ "species_10060689", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000086230" ] }, "reaction_10089341": { "compartment": "compartment_70101", "id": "reaction_10089341", "reactome": "R-BTA-8985153", "name": "OASL binds DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10089337" ], "products": [ "species_10089339" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "ENSBTAT00000004270", "F1MXX7", "ENSBTAT00000004270", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10089696": { "compartment": "compartment_70101", "id": "reaction_10089696", "reactome": "R-BTA-9009936", "name": "RNASEL cleaves cellular ssRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_170292" ], "products": [ "species_9009945" ], "modifiers": [ [ "species_10089693", "catalyst" ] ], "additional_components": [ "A5H027", "ENSBTAT00000044248", "species_113592" ] }, "reaction_10089349": { "compartment": "compartment_70101", "id": "reaction_10089349", "reactome": "R-BTA-8985201", "name": "ABCE1 binds RNASEL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089345", "species_10089343" ], "products": [ "species_10089347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10089703": { "compartment": "compartment_70101", "id": "reaction_10089703", "reactome": "R-BTA-9009950", "name": "PDE12 cleaves 2'-5' oligoadenylates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8983696" ], "products": [ "species_70106", "species_113592", "species_76577" ], "modifiers": [ [ "species_10089700", "catalyst" ] ], "additional_components": [ "species_113592", "ENSBTAT00000020675" ] }, "reaction_10057588": { "compartment": "compartment_876", "id": "reaction_10057588", "reactome": "R-BTA-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057585", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ50", "ENSBTAT00000074252", "E1BGH7", "ENSBTAT00000011399", "F1MLI5", "ENSBTAT00000025779" ] }, "reaction_10091423": { "compartment": "compartment_70101", "id": "reaction_10091423", "reactome": "R-BTA-9647643", "name": "GSDMD (1-275) binds bacterial cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647661", "species_10037243" ], "products": [ "species_10091421" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092350": { "compartment": "compartment_70101", "id": "reaction_10092350", "reactome": "R-BTA-9710106", "name": "ELANE cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10092343", "species_10092345" ], "modifiers": [ [ "species_10092347", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000064480" ] }, "reaction_10091409": { "compartment": "compartment_876", "id": "reaction_10091409", "reactome": "R-BTA-9647619", "name": "GSDMD forms ringshaped oligomers ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081899" ], "products": [ "species_10081901" ], "modifiers": [ [ "species_10052773", "inhibitor" ], [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000087110" ] }, "reaction_10081905": { "compartment": "compartment_984", "id": "reaction_10081905", "reactome": "R-BTA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044670" ], "products": [ "species_10081502" ], "modifiers": [ [ "species_10081901", "catalyst" ], [ "species_10081903", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024094", "ENSBTAT00000024094", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092341": { "compartment": "compartment_70101", "id": "reaction_10092341", "reactome": "R-BTA-9710101", "name": "CASP4, CASP5 cleave GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10092338", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "O75601", "ENSBTAT00000027820" ] }, "reaction_10091415": { "compartment": "compartment_70101", "id": "reaction_10091415", "reactome": "R-BTA-9647631", "name": "GSDMD (1-275) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037243" ], "products": [ "species_10091413" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10091439": { "compartment": "compartment_70101", "id": "reaction_10091439", "reactome": "R-BTA-9647680", "name": "CASP1 cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10050026", "catalyst" ], [ "species_10091437", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "A0A3Q1MFA5", "ENSBTAT00000072083", "ENSBTAT00000087110" ] }, "reaction_10091425": { "compartment": "compartment_70101", "id": "reaction_10091425", "reactome": "R-BTA-9647645", "name": "GSDMD oligomerizes into arc-, slit-shaped structures", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091413", "species_10037243" ], "products": [ "species_10081899" ], "modifiers": [ [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110" ] }, "reaction_10092352": { "compartment": "compartment_70101", "id": "reaction_10092352", "reactome": "R-BTA-9710254", "name": "GSDME oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091427", "species_10037249" ], "products": [ "species_10081903" ], "modifiers": [], "additional_components": [ "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092354": { "compartment": "compartment_70101", "id": "reaction_10092354", "reactome": "R-BTA-9710263", "name": "GZMB cleaves GSDME", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091417" ], "products": [ "species_10037249", "species_10091419" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000013262" ] }, "reaction_10091429": { "compartment": "compartment_70101", "id": "reaction_10091429", "reactome": "R-BTA-9647660", "name": "GSDME (1-270) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037249" ], "products": [ "species_10091427" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10037253": { "compartment": "compartment_17906", "id": "reaction_10037253", "reactome": "R-BTA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037239" ], "products": [ "species_10037211" ], "modifiers": [ [ "species_10037235", "catalyst" ], [ "species_10037245", "catalyst" ], [ "species_10037251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q05KI7", "ENSBTAT00000000549", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10092356": { "compartment": "compartment_70101", "id": "reaction_10092356", "reactome": "R-BTA-9710353", "name": "GSDMD (1-275) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037243" ], "products": [ "species_10037245" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092358": { "compartment": "compartment_70101", "id": "reaction_10092358", "reactome": "R-BTA-9710354", "name": "GSDME (1-270) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037249" ], "products": [ "species_10037251" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10091817": { "compartment": "compartment_70101", "id": "reaction_10091817", "reactome": "R-BTA-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10039151" ], "products": [ "species_10091815" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10056239": { "compartment": "compartment_876", "id": "reaction_10056239", "reactome": "R-BTA-1168636", "name": "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10056236", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LSU3", "ENSBTAT00000068365", "E1BG59", "ENSBTAT00000029159", "species_6797635" ] }, "reaction_10044568": { "compartment": "compartment_7660", "id": "reaction_10044568", "reactome": "R-BTA-264865", "name": "Caspase-mediated cleavage of Lamin A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044551" ], "products": [ "species_10044555", "species_10044553" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023373", "ENSBTAT00000023373", "ENSBTAT00000023373", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10090575": { "compartment": "compartment_13231", "id": "reaction_10090575", "reactome": "R-BTA-9029690", "name": "Caspase-6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044753" ], "products": [ "species_10044565" ], "modifiers": [], "additional_components": [ "G3X702", "ENSBTAT00000016642", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044578": { "compartment": "compartment_7660", "id": "reaction_10044578", "reactome": "R-BTA-264871", "name": "Caspase-mediated cleavage of Lamin B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044572" ], "products": [ "species_10044576", "species_10044574" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075973", "ENSBTAT00000075973", "ENSBTAT00000075973", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10036080": { "compartment": "compartment_7660", "id": "reaction_10036080", "reactome": "R-BTA-77586", "name": "Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036074" ], "products": [ "species_10036078", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1N0Z1", "ENSBTAT00000074628", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10036915": { "compartment": "compartment_7660", "id": "reaction_10036915", "reactome": "R-BTA-111437", "name": "Cleavage of the 3'-end of the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036911" ], "products": [ "species_10036913", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10083967": { "compartment": "compartment_876", "id": "reaction_10083967", "reactome": "R-BTA-8852010", "name": "BTNL2 binds activated T cells surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083963" ], "products": [ "species_10083965" ], "modifiers": [], "additional_components": [ "ENSBTAT00000049415", "A6QNP4", "ENSBTAT00000049415" ] }, "reaction_10083959": { "compartment": "compartment_876", "id": "reaction_10083959", "reactome": "R-BTA-8851988", "name": "BTN2A2 binds T cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083955" ], "products": [ "species_10083957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045031", "F1MZI6", "ENSBTAT00000045031" ] }, "reaction_10046811": { "compartment": "compartment_876", "id": "reaction_10046811", "reactome": "R-BTA-388811", "name": "CD28 homodimer binds B7-1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046779", "species_10046793" ], "products": [ "species_10046809" ], "modifiers": [], "additional_components": [ "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1ND77", "ENSBTAT00000079588" ] }, "reaction_10046907": { "compartment": "compartment_70101", "id": "reaction_10046907", "reactome": "R-BTA-388831", "name": "Phosphorylation of CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037459", "species_113592", "species_10046905" ], "products": [ "species_10046818", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015730", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10047530": { "compartment": "compartment_70101", "id": "reaction_10047530", "reactome": "R-BTA-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_10047527", "species_29370" ], "modifiers": [ [ "species_10047008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000080762" ] }, "reaction_10046932": { "compartment": "compartment_70101", "id": "reaction_10046932", "reactome": "R-BTA-389158", "name": "CD28 bound PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10046929", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046787": { "compartment": "compartment_876", "id": "reaction_10046787", "reactome": "R-BTA-388808", "name": "CD28 homodimer binds B7-2 monomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046783", "species_10046779" ], "products": [ "species_10046785" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1MLL9", "ENSBTAT00000081673" ] }, "reaction_10046943": { "compartment": "compartment_70101", "id": "reaction_10046943", "reactome": "R-BTA-389354", "name": "Activation of Vav1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10046936" ], "products": [ "species_29370", "species_10046940" ], "modifiers": [ [ "species_10037459", "catalyst" ] ], "additional_components": [ "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000015730" ] }, "reaction_10046822": { "compartment": "compartment_70101", "id": "reaction_10046822", "reactome": "R-BTA-388814", "name": "Grb2 binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10035485" ], "products": [ "species_10046820" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046951": { "compartment": "compartment_70101", "id": "reaction_10046951", "reactome": "R-BTA-389381", "name": "Gads binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10046947" ], "products": [ "species_10046949" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000020161", "E1BKA6", "ENSBTAT00000020161", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046834": { "compartment": "compartment_876", "id": "reaction_10046834", "reactome": "R-BTA-388817", "name": "ICOS binds ICOSL/B7-H2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046830", "species_10046826" ], "products": [ "species_10046832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019810", "ENSBTAT00000028775", "Q58DF9", "ENSBTAT00000028775", "E1BCU8", "ENSBTAT00000019810" ] }, "reaction_10046909": { "compartment": "compartment_70101", "id": "reaction_10046909", "reactome": "R-BTA-388833", "name": "Phosphorylation of CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046805", "species_113592", "species_10043788" ], "products": [ "species_29370", "species_10046899", "species_10041566" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10046959": { "compartment": "compartment_70101", "id": "reaction_10046959", "reactome": "R-BTA-389532", "name": "PP2A binds CTLA4 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046801", "species_10041566" ], "products": [ "species_10046803" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046807": { "compartment": "compartment_876", "id": "reaction_10046807", "reactome": "R-BTA-388809", "name": "CTLA-4 binds B7-1/B7-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046803", "species_10046795" ], "products": [ "species_10046805" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046903": { "compartment": "compartment_70101", "id": "reaction_10046903", "reactome": "R-BTA-388829", "name": "SHP2 phosphatase binds CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10046899" ], "products": [ "species_10046901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10075923": { "compartment": "compartment_876", "id": "reaction_10075923", "reactome": "R-BTA-5690669", "name": "CD22 binds itself to form homo-oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075919" ], "products": [ "species_10075921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081458", "A0A3Q1NI55", "ENSBTAT00000081458" ] }, "reaction_10065019": { "compartment": "compartment_453088", "id": "reaction_10065019", "reactome": "R-BTA-2213241", "name": "Formation of nonameric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065015", "species_10064164" ], "products": [ "species_10065017" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178" ] }, "reaction_10064219": { "compartment": "compartment_161320", "id": "reaction_10064219", "reactome": "R-BTA-2130504", "name": "Cleavage of lip22 to lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063931" ], "products": [ "species_10063937" ], "modifiers": [ [ "species_10064216", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "P25326", "ENSBTAT00000022774" ] }, "reaction_10065051": { "compartment": "compartment_161320", "id": "reaction_10065051", "reactome": "R-BTA-2213244", "name": "Loading of antigenic peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065047", "species_2213226" ], "products": [ "species_10065045", "species_10065049" ], "modifiers": [], "additional_components": [ "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10065021": { "compartment": "compartment_20699", "id": "reaction_10065021", "reactome": "R-BTA-2213243", "name": "Fusion of COPII vesicle with Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064275" ], "products": [ "species_10064116", "species_10064225" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064221": { "compartment": "compartment_161320", "id": "reaction_10064221", "reactome": "R-BTA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10065055": { "compartment": "compartment_17938", "id": "reaction_10065055", "reactome": "R-BTA-2213246", "name": "Disassociation of CLIP from MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065045", "species_10063941" ], "products": [ "species_10065047", "species_10065053" ], "modifiers": [], "additional_components": [ "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "ENSBTAT00000074178" ] }, "reaction_10065009": { "compartment": "compartment_24337", "id": "reaction_10065009", "reactome": "R-BTA-2213235", "name": "Trafficking of nonameric complex in the endocytic pathway", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065007" ], "products": [ "species_10063925" ], "modifiers": [], "additional_components": [ "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1ML60", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1N610", "ENSBTAT00000026100", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10084401": { "compartment": "compartment_876", "id": "reaction_10084401", "reactome": "R-BTA-8856157", "name": "LAG3 (CD233) binds MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064210", "species_10084397" ], "products": [ "species_10084399" ], "modifiers": [], "additional_components": [ "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "ENSBTAT00000077596", "A0A3Q1LYZ8", "ENSBTAT00000077596", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10065011": { "compartment": "compartment_453088", "id": "reaction_10065011", "reactome": "R-BTA-2213239", "name": "Formation of MHC II alpha beta heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064162", "species_10064138" ], "products": [ "species_10064164" ], "modifiers": [], "additional_components": [ "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064277": { "compartment": "compartment_13959", "id": "reaction_10064277", "reactome": "R-BTA-2130731", "name": "Formation of COPII vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064225", "species_10064223" ], "products": [ "species_10064275" ], "modifiers": [], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064118": { "compartment": "compartment_263163", "id": "reaction_10064118", "reactome": "R-BTA-2130393", "name": "Transport of MHC II:Ii complex along Golgi to TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064116" ], "products": [ "species_10064020" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064214": { "compartment": "compartment_876", "id": "reaction_10064214", "reactome": "R-BTA-2130500", "name": "Insertion of MHC II:Ii complex in to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064066" ], "products": [ "species_10064212" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064068": { "compartment": "compartment_13946", "id": "reaction_10064068", "reactome": "R-BTA-2130378", "name": "Transport of MHC II:Ii complex to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064020" ], "products": [ "species_10064066" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072" ] }, "reaction_10063972": { "compartment": "compartment_161320", "id": "reaction_10063972", "reactome": "R-BTA-2130349", "name": "Generation of CLIP from lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063937" ], "products": [ "species_10063941" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10042635": { "compartment": "compartment_876", "id": "reaction_10042635", "reactome": "R-BTA-199154", "name": "CD200 binds to CD200R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042631", "species_10042627" ], "products": [ "species_10042633" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027169", "ENSBTAT00000001635", "A5D7V5", "ENSBTAT00000001635", "Q3ZC60", "ENSBTAT00000027169" ] }, "reaction_10042253": { "compartment": "compartment_876", "id": "reaction_10042253", "reactome": "R-BTA-199032", "name": "MADCAM1-1 binds Integrin alpha4beta7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042245", "species_10042249" ], "products": [ "species_10042251" ], "modifiers": [], "additional_components": [ "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279", "ENSBTAT00000068738", "A0A3Q1MBF2", "ENSBTAT00000068738", "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279" ] }, "reaction_10042623": { "compartment": "compartment_876", "id": "reaction_10042623", "reactome": "R-BTA-199112", "name": "CRTAM binds to NECL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042615", "species_10042619" ], "products": [ "species_10042621" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076490", "ENSBTAT00000083396", "A0A3Q1M4X8", "ENSBTAT00000083396", "A7YWT5", "ENSBTAT00000076490" ] }, "reaction_10042129": { "compartment": "compartment_876", "id": "reaction_10042129", "reactome": "R-BTA-198955", "name": "TCR complex interacts with peptide antigen-presenting MHC Class I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042125", "species_10042061" ], "products": [ "species_10042127" ], "modifiers": [], "additional_components": [ "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046" ] }, "reaction_10074993": { "compartment": "compartment_876", "id": "reaction_10074993", "reactome": "R-BTA-5685607", "name": "Sialic acid binds SIGLEC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006168", "species_10074989" ], "products": [ "species_10074991" ], "modifiers": [], "additional_components": [ "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "species_1006168" ] }, "reaction_10075009": { "compartment": "compartment_876", "id": "reaction_10075009", "reactome": "R-BTA-5685608", "name": "CLEC2B binds KLRF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074999", "species_10075005" ], "products": [ "species_10075007" ], "modifiers": [], "additional_components": [ "A5PJG8", "ENSBTAT00000042955", "A0A3Q1NBN7", "ENSBTAT00000082969", "A0A3Q1NBN7", "ENSBTAT00000082969", "A5PJG8", "ENSBTAT00000042955" ] }, "reaction_10084672": { "compartment": "compartment_876", "id": "reaction_10084672", "reactome": "R-BTA-8862090", "name": "PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084640", "species_10084668" ], "products": [ "species_10084670" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001412", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "F1MJX3", "ENSBTAT00000001412" ] }, "reaction_10074899": { "compartment": "compartment_876", "id": "reaction_10074899", "reactome": "R-BTA-5685603", "name": "SAP and EAT2 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074895", "species_10074889" ], "products": [ "species_10074897" ], "modifiers": [], "additional_components": [ "F1MLN1", "ENSBTAT00000034482", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10076963": { "compartment": "compartment_876", "id": "reaction_10076963", "reactome": "R-BTA-5696358", "name": "TREM,CD300 binds lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696348", "species_10076959" ], "products": [ "species_10076961" ], "modifiers": [], "additional_components": [ "species_428256", "species_1500646", "species_1602375", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "species_428256", "species_1500646", "species_1602375" ] }, "reaction_10042786": { "compartment": "compartment_876", "id": "reaction_10042786", "reactome": "R-BTA-199579", "name": "KIR2DL4 interacting with HLA-G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042782", "species_10042780" ], "products": [ "species_10042784" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813" ] }, "reaction_10084658": { "compartment": "compartment_876", "id": "reaction_10084658", "reactome": "R-BTA-8862084", "name": "PILRA,PILRB bind CD99", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084654", "species_10084650" ], "products": [ "species_10084656" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087222", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1NN33", "ENSBTAT00000087222" ] }, "reaction_10074901": { "compartment": "compartment_876", "id": "reaction_10074901", "reactome": "R-BTA-5685604", "name": "SLAMF6 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074893" ], "products": [ "species_10074895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034482", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10043241": { "compartment": "compartment_70101", "id": "reaction_10043241", "reactome": "R-BTA-202354", "name": "Translocation of PLC-gamma1 to PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043234", "species_179856" ], "products": [ "species_10043239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "species_6810412", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043262": { "compartment": "compartment_70101", "id": "reaction_10043262", "reactome": "R-BTA-202407", "name": "PLC-gamma1 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10043259", "catalyst" ] ], "additional_components": [ "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043193": { "compartment": "compartment_70101", "id": "reaction_10043193", "reactome": "R-BTA-202203", "name": "Recruitment of PI3K to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043189", "species_10035523" ], "products": [ "species_10043191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074583", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043225": { "compartment": "compartment_70101", "id": "reaction_10043225", "reactome": "R-BTA-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043006", "species_112275" ], "products": [ "species_10043223" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043219": { "compartment": "compartment_70101", "id": "reaction_10043219", "reactome": "R-BTA-202237", "name": "Hydrolysis of PIP3 to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10043216", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077857" ] }, "reaction_10043252": { "compartment": "compartment_70101", "id": "reaction_10043252", "reactome": "R-BTA-202394", "name": "Translocation of CARMA1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043248", "species_10043180" ], "products": [ "species_10043250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043304": { "compartment": "compartment_70101", "id": "reaction_10043304", "reactome": "R-BTA-202489", "name": "Oligomerization of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043279", "species_10043295" ], "products": [ "species_10043281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043274": { "compartment": "compartment_876", "id": "reaction_10043274", "reactome": "R-BTA-202443", "name": "Oligomerization of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043267", "species_10043265" ], "products": [ "species_10043272" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043244": { "compartment": "compartment_70101", "id": "reaction_10043244", "reactome": "R-BTA-202365", "name": "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10043191", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043212": { "compartment": "compartment_876", "id": "reaction_10043212", "reactome": "R-BTA-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10043209" ], "modifiers": [ [ "species_10043180", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043182": { "compartment": "compartment_70101", "id": "reaction_10043182", "reactome": "R-BTA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202277", "species_10043178" ], "products": [ "species_10043180" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043298": { "compartment": "compartment_70101", "id": "reaction_10043298", "reactome": "R-BTA-202459", "name": "Phosphorylation of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043293" ], "products": [ "species_29370", "species_10043295" ], "modifiers": [ [ "species_10041331", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000020312" ] }, "reaction_10043300": { "compartment": "compartment_70101", "id": "reaction_10043300", "reactome": "R-BTA-202466", "name": "Interaction of Bcl10 to CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043291", "species_10043272" ], "products": [ "species_10043293" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043270": { "compartment": "compartment_70101", "id": "reaction_10043270", "reactome": "R-BTA-202437", "name": "Phosphorylation of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043250", "species_113592" ], "products": [ "species_29370", "species_10043267" ], "modifiers": [ [ "species_10043209", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043302": { "compartment": "compartment_70101", "id": "reaction_10043302", "reactome": "R-BTA-202472", "name": "Translocation of TRAF6 to CBM complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043287", "species_10039473" ], "products": [ "species_10043289" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10055448": { "compartment": "compartment_70101", "id": "reaction_10055448", "reactome": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055446" ], "products": [ "species_983123", "species_10055330" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055451": { "compartment": "compartment_70101", "id": "reaction_10055451", "reactome": "R-BTA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055428", "species_113592", "species_10055422" ], "products": [ "species_111294", "species_10055446", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055428", "catalyst" ] ], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10055453": { "compartment": "compartment_70101", "id": "reaction_10055453", "reactome": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055330", "species_10055422", "species_983035" ], "products": [ "species_10055424" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055491": { "compartment": "compartment_70101", "id": "reaction_10055491", "reactome": "R-BTA-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10055488", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "E1BP91", "ENSBTAT00000015199", "E1BL29", "ENSBTAT00000028490" ] }, "reaction_10055431": { "compartment": "compartment_70101", "id": "reaction_10055431", "reactome": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055424", "species_113592" ], "products": [ "species_111294", "species_10055428", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055330", "catalyst" ] ], "additional_components": [ "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10061657": { "compartment": "compartment_876", "id": "reaction_10061657", "reactome": "R-BTA-1973968", "name": "Beta-defensins 4A and 103 bind CCR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061653", "species_10045084" ], "products": [ "species_10061655" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "ENSBTAT00000018066", "A0A3S5ZP45", "ENSBTAT00000018066", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783" ] }, "reaction_10058456": { "compartment": "compartment_984", "id": "reaction_10058456", "reactome": "R-BTA-1467269", "name": "Beta-defensins bind microbial membranes causing disruption", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058452", "species_1462049" ], "products": [ "species_10058454" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "species_1462049", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10058492": { "compartment": "compartment_984", "id": "reaction_10058492", "reactome": "R-BTA-1471338", "name": "Beta-defensins 1, 4A and 103 bind CCR6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045160", "species_10058488" ], "products": [ "species_10058490" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "F1MT56", "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10058486": { "compartment": "compartment_17963", "id": "reaction_10058486", "reactome": "R-BTA-1471322", "name": "Beta-defensins are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058484" ], "products": [ "species_10058452" ], "modifiers": [], "additional_components": [ "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10063801": { "compartment": "compartment_161320", "id": "reaction_10063801", "reactome": "R-BTA-2090037", "name": "IDUA hydrolyses Heparan sulfate chain(6)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090055" ], "products": [ "species_2090070", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10063803": { "compartment": "compartment_161320", "id": "reaction_10063803", "reactome": "R-BTA-2090038", "name": "NAGLU hydrolyses heparan chain(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090053" ], "products": [ "species_1678743", "species_2065212" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10060634": { "compartment": "compartment_17938", "id": "reaction_10060634", "reactome": "R-BTA-1678660", "name": "HGSNAT oligomer acetylates Heparan sulfate chain(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090040", "species_76183" ], "products": [ "species_2090069", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060685": { "compartment": "compartment_161320", "id": "reaction_10060685", "reactome": "R-BTA-1678742", "name": "NAGLU hydrolyses Heparan sulfate chain(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090069" ], "products": [ "species_2090080", "species_1678743" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10063805": { "compartment": "compartment_17938", "id": "reaction_10063805", "reactome": "R-BTA-2090085", "name": "HGSNAT oligomer acetylates Heparan chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_2090045" ], "products": [ "species_2090053", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060671": { "compartment": "compartment_876", "id": "reaction_10060671", "reactome": "R-BTA-1678694", "name": "Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10060650" ], "products": [ "species_2090023", "species_10060664" ], "modifiers": [ [ "species_10060668", "catalyst" ] ], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "ENSBTAT00000085333" ] }, "reaction_10063022": { "compartment": "compartment_876", "id": "reaction_10063022", "reactome": "R-BTA-2024084", "name": "HS-GAGs translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060650" ], "products": [ "species_10060394" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1MZX8", "ENSBTAT00000011475", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "Q3ZBZ6", "ENSBTAT00000027192" ] }, "reaction_10060625": { "compartment": "compartment_161320", "id": "reaction_10060625", "reactome": "R-BTA-1678650", "name": "IDS hydrolyses Heparan sulfate chain(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090080", "species_1605715" ], "products": [ "species_2090055", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10060741": { "compartment": "compartment_161320", "id": "reaction_10060741", "reactome": "R-BTA-1678854", "name": "GUSB tetramer hydrolyses CS/HS precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065212" ], "products": [ "species_1678868", "species_2090075" ], "modifiers": [ [ "species_10060738", "catalyst" ], [ "species_427963", "inhibitor" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10060678": { "compartment": "compartment_161320", "id": "reaction_10060678", "reactome": "R-BTA-1678716", "name": "IDUA hydrolyses Heparan sulfate chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090033", "species_1605715" ], "products": [ "species_2090072", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10072894": { "compartment": "compartment_17963", "id": "reaction_10072894", "reactome": "R-BTA-5653878", "name": "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_964746" ], "products": [ "species_5653871", "species_205687" ], "modifiers": [ [ "species_10072891", "catalyst" ] ], "additional_components": [ "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10072898": { "compartment": "compartment_17963", "id": "reaction_10072898", "reactome": "R-BTA-5653886", "name": "B4GALT1 binds LALBA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072896", "species_10054442" ], "products": [ "species_10072891" ], "modifiers": [ [ "species_735682", "catalyst" ], [ "species_5653875", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066421", "ENSBTAT00000020286", "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10033611": { "compartment": "compartment_70101", "id": "reaction_10033611", "reactome": "R-BTA-70449", "name": "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_29578", "species_29360" ], "products": [ "species_70106", "species_29800", "species_73473" ], "modifiers": [ [ "species_10033608", "catalyst" ] ], "additional_components": [ "P10096", "ENSBTAT00000037753", "Q2KJE5", "ENSBTAT00000021166" ] }, "reaction_10080765": { "compartment": "compartment_70101", "id": "reaction_10080765", "reactome": "R-BTA-6799604", "name": "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449701" ], "products": [ "species_29512", "species_31633" ], "modifiers": [ [ "species_10080762", "catalyst" ] ], "additional_components": [ "A0A452DIC9", "ENSBTAT00000000357" ] }, "reaction_10033629": { "compartment": "compartment_70101", "id": "reaction_10033629", "reactome": "R-BTA-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_30014", "species_29370" ], "modifiers": [ [ "species_10033626", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_76190", "inhibitor" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "A1A4J1", "ENSBTAT00000056305" ] }, "reaction_10034157": { "compartment": "compartment_70101", "id": "reaction_10034157", "reactome": "R-BTA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10034154", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "species_29926", "species_74126", "Q1JPG7", "ENSBTAT00000086042", "A5D984", "ENSBTAT00000047412" ] }, "reaction_10034140": { "compartment": "compartment_70101", "id": "reaction_10034140", "reactome": "R-BTA-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10034049", "catalyst" ] ], "additional_components": [ "Q3SZ62", "ENSBTAT00000032937" ] }, "reaction_10076815": { "compartment": "compartment_12045", "id": "reaction_10076815", "reactome": "R-BTA-5696021", "name": "ADPGK:Mg2+ phosphorylates Glc to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_70113" ], "products": [ "species_30537", "species_76577" ], "modifiers": [ [ "species_10076812", "catalyst" ] ], "additional_components": [ "species_29926", "A2VE47", "ENSBTAT00000002065" ] }, "reaction_10088737": { "compartment": "compartment_70101", "id": "reaction_10088737", "reactome": "R-BTA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10033547", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926" ] }, "reaction_10033620": { "compartment": "compartment_70101", "id": "reaction_10033620", "reactome": "R-BTA-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10033617", "catalyst" ] ], "additional_components": [ "A0A452DIX3", "ENSBTAT00000026358" ] }, "reaction_10034071": { "compartment": "compartment_70101", "id": "reaction_10034071", "reactome": "R-BTA-71496", "name": "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014" ], "products": [ "species_29578", "species_75970" ], "modifiers": [ [ "species_10034066", "catalyst" ] ], "additional_components": [ "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416" ] }, "reaction_10078710": { "compartment": "compartment_70101", "id": "reaction_10078710", "reactome": "R-BTA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10078707", "catalyst" ] ], "additional_components": [ "F1MX69", "ENSBTAT00000070308" ] }, "reaction_10045050": { "compartment": "compartment_70101", "id": "reaction_10045050", "reactome": "R-BTA-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10033757": { "compartment": "compartment_5460", "id": "reaction_10033757", "reactome": "R-BTA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10041885": { "compartment": "compartment_70101", "id": "reaction_10041885", "reactome": "R-BTA-198513", "name": "Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10041882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077820" ] }, "reaction_10045692": { "compartment": "compartment_70101", "id": "reaction_10045692", "reactome": "R-BTA-376851", "name": "Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_198498" ], "products": [ "species_29406", "species_113544" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10034238": { "compartment": "compartment_17957", "id": "reaction_10034238", "reactome": "R-BTA-71825", "name": "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10034235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013436" ] }, "reaction_10045043": { "compartment": "compartment_5460", "id": "reaction_10045043", "reactome": "R-BTA-372819", "name": "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113573", "species_113587" ], "products": [ "species_372364", "species_113525", "species_29376" ], "modifiers": [ [ "species_10045040", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015834" ] }, "reaction_10041878": { "compartment": "compartment_70101", "id": "reaction_10041878", "reactome": "R-BTA-198440", "name": "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_113544" ], "products": [ "species_113594", "species_198498" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10033718": { "compartment": "compartment_70101", "id": "reaction_10033718", "reactome": "R-BTA-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29448" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10067254": { "compartment": "compartment_17957", "id": "reaction_10067254", "reactome": "R-BTA-3266566", "name": "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005552" ] }, "reaction_10067240": { "compartment": "compartment_70101", "id": "reaction_10067240", "reactome": "R-BTA-3257122", "name": "SLC37A1, SLC37A2 exchange G6P for Pi across the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10067237", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069229" ] }, "reaction_10067247": { "compartment": "compartment_17957", "id": "reaction_10067247", "reactome": "R-BTA-3262512", "name": "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021621" ] }, "reaction_10045029": { "compartment": "compartment_70101", "id": "reaction_10045029", "reactome": "R-BTA-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10045026", "catalyst" ] ], "additional_components": [ "A0A3Q1M9V5", "ENSBTAT00000083179", "A0A3Q1LHX4", "ENSBTAT00000073854" ] }, "reaction_10033638": { "compartment": "compartment_70101", "id": "reaction_10033638", "reactome": "R-BTA-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10033635", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "Q3SZB7", "ENSBTAT00000012835" ] }, "reaction_10033561": { "compartment": "compartment_70101", "id": "reaction_10033561", "reactome": "R-BTA-70333", "name": "KHK dimer phosphorylates Fru to Fru 1-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29532", "species_113592" ], "products": [ "species_29370", "species_31221" ], "modifiers": [ [ "species_10033558", "catalyst" ], [ "species_29804", "catalyst" ], [ "species_29370", "inhibitor" ] ], "additional_components": [ "Q0II75", "ENSBTAT00000015052" ] }, "reaction_10083115": { "compartment": "compartment_70101", "id": "reaction_10083115", "reactome": "R-BTA-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30393", "species_29360" ], "products": [ "species_6799497", "species_70106", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10033570": { "compartment": "compartment_70101", "id": "reaction_10033570", "reactome": "R-BTA-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_113592" ], "products": [ "species_29578", "species_29370" ], "modifiers": [ [ "species_10033567", "catalyst" ] ], "additional_components": [ "A0A3Q1MGZ4", "ENSBTAT00000085239", "species_29926" ] }, "reaction_10072825": { "compartment": "compartment_70101", "id": "reaction_10072825", "reactome": "R-BTA-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10063530": { "compartment": "compartment_20699", "id": "reaction_10063530", "reactome": "R-BTA-2046285", "name": "The keratan chain can be capped by N-acetylneuraminic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10063528" ], "products": [ "species_10063493", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10063485": { "compartment": "compartment_17963", "id": "reaction_10063485", "reactome": "R-BTA-2046180", "name": "KSPG is secreted from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063470" ], "products": [ "species_10063483" ], "modifiers": [], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854" ] }, "reaction_10063532": { "compartment": "compartment_20699", "id": "reaction_10063532", "reactome": "R-BTA-2046298", "name": "B4GALTs transfer Gal to a branch of keratan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063518" ], "products": [ "species_205687", "species_10063528" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063249": { "compartment": "compartment_20699", "id": "reaction_10063249", "reactome": "R-BTA-2025724", "name": "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10063230" ], "products": [ "species_205687", "species_10063240" ], "modifiers": [ [ "species_10063246", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A7YY64", "ENSBTAT00000024024", "Q5EA01", "ENSBTAT00000030023", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494" ] }, "reaction_10063232": { "compartment": "compartment_20699", "id": "reaction_10063232", "reactome": "R-BTA-2025723", "name": "B4GALTs transfer Gal to the N-glycan precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063222", "species_735682" ], "products": [ "species_10063230", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063520": { "compartment": "compartment_20699", "id": "reaction_10063520", "reactome": "R-BTA-2046265", "name": "B4GALTs transfer Gal to the keratan chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063240" ], "products": [ "species_10063518", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063477": { "compartment": "compartment_20699", "id": "reaction_10063477", "reactome": "R-BTA-2046175", "name": "Further sulfation on galactose residues produces KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063464" ], "products": [ "species_742343", "species_10063470" ], "modifiers": [ [ "species_10063474", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "ENSBTAT00000004844" ] }, "reaction_10063508": { "compartment": "compartment_20699", "id": "reaction_10063508", "reactome": "R-BTA-2046222", "name": "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063493", "species_741440" ], "products": [ "species_742343", "species_10063464" ], "modifiers": [ [ "species_10063505", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "E1BMN6", "ENSBTAT00000015389", "E1BK55", "ENSBTAT00000056191" ] }, "reaction_10060825": { "compartment": "compartment_161320", "id": "reaction_10060825", "reactome": "R-BTA-1793182", "name": "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065213" ], "products": [ "species_2065269", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10091289": { "compartment": "compartment_161320", "id": "reaction_10091289", "reactome": "R-BTA-9638075", "name": "HEXB cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060827": { "compartment": "compartment_161320", "id": "reaction_10060827", "reactome": "R-BTA-1793186", "name": "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105025" ], "products": [ "species_2104993", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10060842": { "compartment": "compartment_161320", "id": "reaction_10060842", "reactome": "R-BTA-1793209", "name": "HYAL1 hydrolyses Chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065257" ], "products": [ "species_2065212" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "CHEBI:63515", "species_2065239", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10060829": { "compartment": "compartment_161320", "id": "reaction_10060829", "reactome": "R-BTA-1793207", "name": "ARSB hydrolyses C4S/C6S chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2065251", "species_1605715" ], "products": [ "species_2065239", "species_1606845" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10062655": { "compartment": "compartment_984", "id": "reaction_10062655", "reactome": "R-BTA-2022056", "name": "DSPG and CSPG translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062551", "species_10062589" ], "products": [ "species_10062627", "species_10062653" ], "modifiers": [], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562" ] }, "reaction_10060031": { "compartment": "compartment_161320", "id": "reaction_10060031", "reactome": "R-BTA-1606789", "name": "ARSB hydrolyses DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065231" ], "products": [ "species_1606845", "species_2065213" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10063807": { "compartment": "compartment_161320", "id": "reaction_10063807", "reactome": "R-BTA-2105001", "name": "HEXA cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10061642": { "compartment": "compartment_20699", "id": "reaction_10061642", "reactome": "R-BTA-1971487", "name": "CHPF,CHSY3 transfer GalNAc to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10061629" ], "products": [ "species_10061574", "species_205687" ], "modifiers": [ [ "species_10061639", "catalyst" ] ], "additional_components": [ "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10061612": { "compartment": "compartment_20699", "id": "reaction_10061612", "reactome": "R-BTA-1971483", "name": "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_10061591", "species_742343" ], "modifiers": [ [ "species_10061609", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N663", "ENSBTAT00000014069", "A0A3Q1M362", "ENSBTAT00000073469", "A6QLZ9", "ENSBTAT00000011567", "A0A3Q1MTD8", "ENSBTAT00000068924" ] }, "reaction_10062463": { "compartment": "compartment_20699", "id": "reaction_10062463", "reactome": "R-BTA-2018682", "name": "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_742343", "species_10062450" ], "modifiers": [ [ "species_10062460", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "G3X6P1", "ENSBTAT00000010069", "E1BPN4", "ENSBTAT00000074793" ] }, "reaction_10061651": { "compartment": "compartment_20699", "id": "reaction_10061651", "reactome": "R-BTA-1971491", "name": "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061557" ], "products": [ "species_10061629", "species_205687" ], "modifiers": [ [ "species_10061648", "catalyst" ] ], "additional_components": [ "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "E1B9D0", "ENSBTAT00000019108", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10063014": { "compartment": "compartment_17963", "id": "reaction_10063014", "reactome": "R-BTA-2022911", "name": "CSPG is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063012" ], "products": [ "species_10062589" ], "modifiers": [], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562" ] }, "reaction_10061402": { "compartment": "compartment_20699", "id": "reaction_10061402", "reactome": "R-BTA-1889981", "name": "B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061238", "species_735682" ], "products": [ "species_10061388", "species_205687" ], "modifiers": [ [ "species_10061399", "catalyst" ] ], "additional_components": [ "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000035663" ] }, "reaction_10061251": { "compartment": "compartment_20699", "id": "reaction_10061251", "reactome": "R-BTA-1878002", "name": "XYLTs transfer Xyl to core protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061200", "species_742361" ], "products": [ "species_10061238", "species_205687" ], "modifiers": [ [ "species_10061248", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MY84", "ENSBTAT00000016206", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q0VCM1", "ENSBTAT00000002979", "Q3ZBZ6", "ENSBTAT00000027192", "P21793", "ENSBTAT00000004562", "F1MZX8", "ENSBTAT00000011475", "F1N2Y8", "ENSBTAT00000002312", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1N211", "ENSBTAT00000007264", "A0A3Q1LSF3", "ENSBTAT00000070229" ] }, "reaction_10061395": { "compartment": "compartment_20699", "id": "reaction_10061395", "reactome": "R-BTA-1889978", "name": "B3GALT6 transfers Gal to the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10061388" ], "products": [ "species_205687", "species_10061289" ], "modifiers": [ [ "species_10061392", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "ENSBTAT00000057493" ] }, "reaction_10061350": { "compartment": "compartment_20699", "id": "reaction_10061350", "reactome": "R-BTA-1889955", "name": "B3GAT dimers transfer GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061347", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1M0B6", "ENSBTAT00000083529", "species_113527", "A0A3Q1LG25", "ENSBTAT00000080834", "F1MQ60", "ENSBTAT00000070592" ] }, "reaction_10091286": { "compartment": "compartment_20699", "id": "reaction_10091286", "reactome": "R-BTA-9638064", "name": "B3GAT3 dimer transfers GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061345", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1LG25", "ENSBTAT00000080834", "species_113527" ] }, "reaction_10062697": { "compartment": "compartment_20699", "id": "reaction_10062697", "reactome": "R-BTA-2022063", "name": "CHST14 transfers SO4(2-) to GalNAc in dermatan or DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062676", "species_741440" ], "products": [ "species_742343", "species_10062690" ], "modifiers": [ [ "species_10062694", "catalyst" ] ], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000005795" ] }, "reaction_10062701": { "compartment": "compartment_17963", "id": "reaction_10062701", "reactome": "R-BTA-2022065", "name": "DSPGs are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062699" ], "products": [ "species_10062551" ], "modifiers": [], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312" ] }, "reaction_10062508": { "compartment": "compartment_20699", "id": "reaction_10062508", "reactome": "R-BTA-2022052", "name": "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062465" ], "products": [ "species_10062501" ], "modifiers": [ [ "species_10062505", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000056960" ] }, "reaction_10062674": { "compartment": "compartment_20699", "id": "reaction_10062674", "reactome": "R-BTA-2022061", "name": "Dermatan sulfate can be further sulfated on position 2 of iduronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10062482" ], "products": [ "species_742343", "species_10062667" ], "modifiers": [ [ "species_10062671", "catalyst" ] ], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000068674" ] }, "reaction_10039887": { "compartment": "compartment_70101", "id": "reaction_10039887", "reactome": "R-BTA-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174370" ], "products": [ "species_29370", "species_158471" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10039890": { "compartment": "compartment_70101", "id": "reaction_10039890", "reactome": "R-BTA-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174375" ], "products": [ "species_111294", "species_174370" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10051570": { "compartment": "compartment_20699", "id": "reaction_10051570", "reactome": "R-BTA-741449", "name": "SLC35B2,3 transport cytosolic PAPS to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471" ], "products": [ "species_741440" ], "modifiers": [ [ "species_10051567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010620" ] }, "reaction_10048727": { "compartment": "compartment_876", "id": "reaction_10048727", "reactome": "R-BTA-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_427648" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10048724", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019462" ] }, "reaction_10064353": { "compartment": "compartment_876", "id": "reaction_10064353", "reactome": "R-BTA-2160851", "name": "HAS1,2,3 mediate the polymerisation of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142867" ], "products": [ "species_2142896" ], "modifiers": [ [ "species_10064350", "catalyst" ] ], "additional_components": [ "species_2162224", "ENSBTAT00000071722" ] }, "reaction_10064393": { "compartment": "compartment_876", "id": "reaction_10064393", "reactome": "R-BTA-2160915", "name": "Receptor-mediated uptake of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064359", "species_10064373", "species_2160848" ], "products": [ "species_10064375" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070191", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "species_2162224", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10091291": { "compartment": "compartment_161320", "id": "reaction_10091291", "reactome": "R-BTA-9638076", "name": "HEXB cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064593": { "compartment": "compartment_161320", "id": "reaction_10064593", "reactome": "R-BTA-2162225", "name": "HEXA cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064355": { "compartment": "compartment_161320", "id": "reaction_10064355", "reactome": "R-BTA-2160874", "name": "HYAL1 hydrolyses (HA)50", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160864" ], "products": [ "species_2160866" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "species_2162224", "species_2162224", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10064595": { "compartment": "compartment_161320", "id": "reaction_10064595", "reactome": "R-BTA-2162226", "name": "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2162224" ], "products": [ "species_1678743", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064597": { "compartment": "compartment_161320", "id": "reaction_10064597", "reactome": "R-BTA-2162227", "name": "GUSB tetramer hydrolyses (HA)2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160866" ], "products": [ "species_2162223", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "species_2162224", "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064391": { "compartment": "compartment_876", "id": "reaction_10064391", "reactome": "R-BTA-2160892", "name": "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064388" ], "products": [ "species_2160894", "species_10064388" ], "modifiers": [ [ "species_10064388", "catalyst" ] ], "additional_components": [ "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "species_2162224", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10033579": { "compartment": "compartment_70101", "id": "reaction_10033579", "reactome": "R-BTA-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10033576", "catalyst" ] ], "additional_components": [ "species_29360", "A0A452DIP2", "ENSBTAT00000006586" ] }, "reaction_10033594": { "compartment": "compartment_70101", "id": "reaction_10033594", "reactome": "R-BTA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10033549", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10090620": { "compartment": "compartment_70101", "id": "reaction_10090620", "reactome": "R-BTA-9033959", "name": "ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_9033793" ], "products": [ "species_205687", "species_9033802" ], "modifiers": [ [ "species_10090617", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090703": { "compartment": "compartment_17963", "id": "reaction_10090703", "reactome": "R-BTA-9036987", "name": "FUT2 transfers Fuc to Type 1 chains to form H antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9037036" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090638": { "compartment": "compartment_984", "id": "reaction_10090638", "reactome": "R-BTA-9034042", "name": "sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034046" ], "products": [ "species_417888", "species_9037066" ], "modifiers": [ [ "species_10090635", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090611": { "compartment": "compartment_17963", "id": "reaction_10090611", "reactome": "R-BTA-9033949", "name": "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_205689", "species_9033793" ], "modifiers": [ [ "species_10090608", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023560" ] }, "reaction_10090645": { "compartment": "compartment_984", "id": "reaction_10090645", "reactome": "R-BTA-9034053", "name": "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034065" ], "products": [ "species_417888", "species_9037067" ], "modifiers": [ [ "species_10090642", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090631": { "compartment": "compartment_70101", "id": "reaction_10090631", "reactome": "R-BTA-9033961", "name": "ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_9033793" ], "products": [ "species_9033798", "species_205687" ], "modifiers": [ [ "species_10090628", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090856": { "compartment": "compartment_17963", "id": "reaction_10090856", "reactome": "R-BTA-9605644", "name": "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605649", "species_205683" ], "products": [ "species_205689", "species_9605651" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090797": { "compartment": "compartment_17963", "id": "reaction_10090797", "reactome": "R-BTA-9603984", "name": "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_9605593", "species_205689" ], "modifiers": [ [ "species_10090794", "catalyst" ] ], "additional_components": [ "F1MDG4", "ENSBTAT00000056091", "F1MBS8", "ENSBTAT00000000529", "F1N751", "ENSBTAT00000010501" ] }, "reaction_10090799": { "compartment": "compartment_17963", "id": "reaction_10090799", "reactome": "R-BTA-9603986", "name": "FUT3 transfers Fuc to Type 1 chains to form LeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9605607" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090819": { "compartment": "compartment_17963", "id": "reaction_10090819", "reactome": "R-BTA-9603989", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9604808", "species_735682" ], "products": [ "species_205687", "species_9036984" ], "modifiers": [ [ "species_10090816", "catalyst" ] ], "additional_components": [ "Q2HJA3", "ENSBTAT00000036248", "F1MSJ4", "ENSBTAT00000031889", "Q3T0R9", "ENSBTAT00000022206" ] }, "reaction_10090851": { "compartment": "compartment_17963", "id": "reaction_10090851", "reactome": "R-BTA-9605600", "name": "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9033790" ], "products": [ "species_727810", "species_9605685" ], "modifiers": [ [ "species_10090848", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324" ] }, "reaction_10090867": { "compartment": "compartment_17963", "id": "reaction_10090867", "reactome": "R-BTA-9605682", "name": "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605685", "species_205683" ], "products": [ "species_9605661", "species_205689" ], "modifiers": [ [ "species_10090864", "catalyst" ] ], "additional_components": [ "G3MZR2", "ENSBTAT00000066072", "F1MBS8", "ENSBTAT00000000529" ] }, "reaction_10090802": { "compartment": "compartment_17963", "id": "reaction_10090802", "reactome": "R-BTA-9603987", "name": "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9036984" ], "products": [ "species_727810", "species_9605595" ], "modifiers": [ [ "species_10054713", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078218" ] }, "reaction_10090772": { "compartment": "compartment_17963", "id": "reaction_10090772", "reactome": "R-BTA-9603982", "name": "FUT2 transfers Fuc to LeA to form LeB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605607", "species_205683" ], "products": [ "species_205689", "species_9605394" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090774": { "compartment": "compartment_17963", "id": "reaction_10090774", "reactome": "R-BTA-9603983", "name": "FUT2 transfers Fuc to LeX to form LeY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605593", "species_205683" ], "products": [ "species_205689", "species_9605586" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090854": { "compartment": "compartment_17963", "id": "reaction_10090854", "reactome": "R-BTA-9605609", "name": "FUT3 transfers Fuc to Type 1 MSGG to form sLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605595", "species_205683" ], "products": [ "species_9605615", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090822": { "compartment": "compartment_17963", "id": "reaction_10090822", "reactome": "R-BTA-9603991", "name": "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9605595" ], "products": [ "species_727810", "species_9605649" ], "modifiers": [ [ "species_10069341", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061027" ] }, "reaction_10034041": { "compartment": "compartment_70101", "id": "reaction_10034041", "reactome": "R-BTA-71324", "name": "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_73578" ], "products": [ "species_29882", "species_29578" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10033592": { "compartment": "compartment_70101", "id": "reaction_10033592", "reactome": "R-BTA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10033589", "catalyst" ] ], "additional_components": [ "A0A3Q1MM55", "ENSBTAT00000067626", "species_113563" ] }, "reaction_10034043": { "compartment": "compartment_70101", "id": "reaction_10034043", "reactome": "R-BTA-71335", "name": "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_29878" ], "products": [ "species_29578", "species_29512" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10034013": { "compartment": "compartment_70101", "id": "reaction_10034013", "reactome": "R-BTA-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29996", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_29732" ], "modifiers": [ [ "species_10034010", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM3", "ENSBTAT00000017988" ] }, "reaction_10042801": { "compartment": "compartment_70101", "id": "reaction_10042801", "reactome": "R-BTA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10034032": { "compartment": "compartment_70101", "id": "reaction_10034032", "reactome": "R-BTA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10088744": { "compartment": "compartment_70101", "id": "reaction_10088744", "reactome": "R-BTA-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_73578", "species_29370" ], "modifiers": [ [ "species_10088741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044396" ] }, "reaction_10089230": { "compartment": "compartment_70101", "id": "reaction_10089230", "reactome": "R-BTA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10077793": { "compartment": "compartment_70101", "id": "reaction_10077793", "reactome": "R-BTA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10088898": { "compartment": "compartment_70101", "id": "reaction_10088898", "reactome": "R-BTA-8959719", "name": "SHPK phosphorylates Sedo to Sedo7P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8959707" ], "products": [ "species_70106", "species_29370", "species_29882" ], "modifiers": [ [ "species_10088895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001095" ] }, "reaction_10073438": { "compartment": "compartment_70101", "id": "reaction_10073438", "reactome": "R-BTA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10073431": { "compartment": "compartment_70101", "id": "reaction_10073431", "reactome": "R-BTA-5661240", "name": "DCXR tetramer reduces L-xylulose to xylitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_5660036" ], "products": [ "species_5660033", "species_29366" ], "modifiers": [ [ "species_10073428", "catalyst" ] ], "additional_components": [ "A5PJR3", "ENSBTAT00000085766", "Q1JP75", "ENSBTAT00000085766" ] }, "reaction_10080747": { "compartment": "compartment_70101", "id": "reaction_10080747", "reactome": "R-BTA-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6799540" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10080744", "catalyst" ] ], "additional_components": [ "species_29426", "F1MWT0", "ENSBTAT00000009690" ] }, "reaction_10084129": { "compartment": "compartment_161320", "id": "reaction_10084129", "reactome": "R-BTA-8853686", "name": "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_8853396" ], "products": [ "species_6799577", "species_6799594" ], "modifiers": [ [ "species_10084126", "catalyst" ] ], "additional_components": [ "Q29451", "ENSBTAT00000070599", "species_29426" ] }, "reaction_10080756": { "compartment": "compartment_161320", "id": "reaction_10080756", "reactome": "R-BTA-6799581", "name": "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799577", "species_1605715" ], "products": [ "species_6799594", "species_8853719" ], "modifiers": [ [ "species_10080753", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ5", "ENSBTAT00000081381", "species_29426" ] }, "reaction_10067610": { "compartment": "compartment_70101", "id": "reaction_10067610", "reactome": "R-BTA-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067605", "species_29410" ], "products": [ "species_10067607", "species_110096" ], "modifiers": [ [ "species_10067605", "catalyst" ] ], "additional_components": [ "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10067644": { "compartment": "compartment_70101", "id": "reaction_10067644", "reactome": "R-BTA-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067619", "species_29410" ], "products": [ "species_110096", "species_10067641" ], "modifiers": [ [ "species_10067619", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10068748": { "compartment": "compartment_70101", "id": "reaction_10068748", "reactome": "R-BTA-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068745" ], "products": [ "species_10068740", "species_29372" ], "modifiers": [ [ "species_10068745", "catalyst" ] ], "additional_components": [ "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067648": { "compartment": "compartment_70101", "id": "reaction_10067648", "reactome": "R-BTA-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067641" ], "products": [ "species_10067646" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "ENSBTAT00000083071" ] }, "reaction_10068752": { "compartment": "compartment_70101", "id": "reaction_10068752", "reactome": "R-BTA-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067627", "species_10068729" ], "products": [ "species_10068750" ], "modifiers": [], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10068755": { "compartment": "compartment_70101", "id": "reaction_10068755", "reactome": "R-BTA-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068750", "species_29410" ], "products": [ "species_109402", "species_10068734" ], "modifiers": [ [ "species_10068750", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067634": { "compartment": "compartment_70101", "id": "reaction_10067634", "reactome": "R-BTA-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067607" ], "products": [ "species_10067627" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000083071" ] }, "reaction_10067639": { "compartment": "compartment_70101", "id": "reaction_10067639", "reactome": "R-BTA-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067636", "species_29410" ], "products": [ "species_10067605", "species_110096" ], "modifiers": [ [ "species_10067636", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067622": { "compartment": "compartment_70101", "id": "reaction_10067622", "reactome": "R-BTA-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067617", "species_29410" ], "products": [ "species_10067619", "species_110096" ], "modifiers": [ [ "species_10067617", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926" ] }, "reaction_10090696": { "compartment": "compartment_161320", "id": "reaction_10090696", "reactome": "R-BTA-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10090685" ], "products": [ "species_1605745", "species_10090689" ], "modifiers": [ [ "species_10090691", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "ENSBTAT00000021325" ] }, "reaction_10034138": { "compartment": "compartment_70101", "id": "reaction_10034138", "reactome": "R-BTA-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034111" ], "products": [ "species_10034135", "species_70113" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10050637": { "compartment": "compartment_70101", "id": "reaction_10050637", "reactome": "R-BTA-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050635" ], "products": [ "species_10034078", "species_76577" ], "modifiers": [], "additional_components": [ "species_76577", "F1MJ28", "ENSBTAT00000001373", "F1MJ28", "ENSBTAT00000001373" ] }, "reaction_10034118": { "compartment": "compartment_70101", "id": "reaction_10034118", "reactome": "R-BTA-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034099" ], "products": [ "species_10034111" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10033737": { "compartment": "compartment_70101", "id": "reaction_10033737", "reactome": "R-BTA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10033734", "catalyst" ] ], "additional_components": [ "Q1LZA3", "ENSBTAT00000079655" ] }, "reaction_10078529": { "compartment": "compartment_70101", "id": "reaction_10078529", "reactome": "R-BTA-6797627", "name": "ASPG hydrolyses L-Asn to L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29642" ], "products": [ "species_29448", "species_29382" ], "modifiers": [ [ "species_10078526", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066927" ] }, "reaction_10033728": { "compartment": "compartment_5460", "id": "reaction_10033728", "reactome": "R-BTA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10076130": { "compartment": "compartment_70101", "id": "reaction_10076130", "reactome": "R-BTA-5691507", "name": "ASPA deacetylates NAA to acetate and L-aspartate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5691492" ], "products": [ "species_29416", "species_29448" ], "modifiers": [ [ "species_10076127", "catalyst" ] ], "additional_components": [ "F1MUZ8", "ENSBTAT00000069554", "species_29426" ] }, "reaction_10033716": { "compartment": "compartment_70101", "id": "reaction_10033716", "reactome": "R-BTA-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_76213" ], "products": [ "species_29406", "species_29448" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10076406": { "compartment": "compartment_876", "id": "reaction_10076406", "reactome": "R-BTA-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10076403", "catalyst" ] ], "additional_components": [ "F1MUP1", "ENSBTAT00000009723", "F1MGS8", "ENSBTAT00000000354" ] }, "reaction_10043917": { "compartment": "compartment_70101", "id": "reaction_10043917", "reactome": "R-BTA-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914", "species_76183" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10043914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019543" ] }, "reaction_10043948": { "compartment": "compartment_70101", "id": "reaction_10043948", "reactome": "R-BTA-209828", "name": "Tryptophan is hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29500", "species_29368" ], "products": [ "species_71112", "species_209911" ], "modifiers": [ [ "species_10043945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N5Q8", "ENSBTAT00000007030", "E1BGX6", "ENSBTAT00000027708" ] }, "reaction_10033681": { "compartment": "compartment_70101", "id": "reaction_10033681", "reactome": "R-BTA-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10033678", "catalyst" ] ], "additional_components": [ "A0A452DIW8", "ENSBTAT00000010309" ] }, "reaction_10091773": { "compartment": "compartment_876", "id": "reaction_10091773", "reactome": "R-BTA-9686930", "name": "RIPK3 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070522" ], "products": [ "species_10091771", "species_10091769" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000024511", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068030": { "compartment": "compartment_70101", "id": "reaction_10068030", "reactome": "R-BTA-3465429", "name": "FLIP(S) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035394", "species_10068026" ], "products": [ "species_10068028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074240": { "compartment": "compartment_70101", "id": "reaction_10074240", "reactome": "R-BTA-5675456", "name": "FLIP(L) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068034", "species_10068026" ], "products": [ "species_10068032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074254": { "compartment": "compartment_70101", "id": "reaction_10074254", "reactome": "R-BTA-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10071514" ], "products": [ "species_10074251" ], "modifiers": [ [ "species_10071514", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103" ] }, "reaction_10091806": { "compartment": "compartment_70101", "id": "reaction_10091806", "reactome": "R-BTA-9688831", "name": "STUB1 ubiquitinates RIPK3 at K55, K363", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091797", "species_10033408" ], "products": [ "species_10091803" ], "modifiers": [ [ "species_10091797", "catalyst" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091793": { "compartment": "compartment_70101", "id": "reaction_10091793", "reactome": "R-BTA-9687828", "name": "O-GlcNAcylation of RIPK3 (TLR4 signaling)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_10070522" ], "products": [ "species_10091786", "species_110096" ], "modifiers": [ [ "species_10091790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000045447" ] }, "reaction_10091808": { "compartment": "compartment_70101", "id": "reaction_10091808", "reactome": "R-BTA-9688832", "name": "MLKL binds PDCD6IP and SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072342", "species_10045220", "species_10067330" ], "products": [ "species_10072344" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023165", "ENSBTAT00000026526", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165" ] }, "reaction_10091779": { "compartment": "compartment_70101", "id": "reaction_10091779", "reactome": "R-BTA-9687625", "name": "ATP binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_10091777" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "species_113592", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10091810": { "compartment": "compartment_70101", "id": "reaction_10091810", "reactome": "R-BTA-9688838", "name": "RIPK3 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091795", "species_10070522" ], "products": [ "species_10091797" ], "modifiers": [], "additional_components": [ "E1B7G3", "ENSBTAT00000025473", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091783": { "compartment": "compartment_70101", "id": "reaction_10091783", "reactome": "R-BTA-9687638", "name": "MLKL binds IP4, IP5 and IP6 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994146", "species_10070686", "species_1629770", "species_994141" ], "products": [ "species_10091781" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_994141", "species_1629770", "species_994146" ] }, "reaction_10081481": { "compartment": "compartment_161320", "id": "reaction_10081481", "reactome": "R-BTA-6803753", "name": "NAAA hydrolyses NAEs to FAs and ethanolamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6803725" ], "products": [ "species_6803745", "species_6803778" ], "modifiers": [ [ "species_10081478", "catalyst" ] ], "additional_components": [ "CHEBI:71466", "species_5693754", "CHEBI:85299", "CHEBI:85263", "CHEBI:71464", "CHEBI:85262", "species_426576", "species_33549", "species_8934421", "CHEBI:28875", "CHEBI:16196", "species_140356", "F1MN16", "ENSBTAT00000025945" ] }, "reaction_10044540": { "compartment": "compartment_70101", "id": "reaction_10044540", "reactome": "R-BTA-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_264643", "species_76194" ], "modifiers": [ [ "species_10044537", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022369" ] }, "reaction_10049090": { "compartment": "compartment_876", "id": "reaction_10049090", "reactome": "R-BTA-429594", "name": "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_264638", "species_74113" ], "products": [ "species_264618", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049087", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005693" ] }, "reaction_10071437": { "compartment": "compartment_70101", "id": "reaction_10071437", "reactome": "R-BTA-5336443", "name": "LIN7, CASK and APBA1 bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071423", "species_10071419", "species_10071433" ], "products": [ "species_10071435" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071329", "ENSBTAT00000079326", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "A0A3Q1MLH9", "ENSBTAT00000079326", "A0A3Q1LPV4", "ENSBTAT00000071329" ] }, "reaction_10049583": { "compartment": "compartment_70101", "id": "reaction_10049583", "reactome": "R-BTA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049580", "catalyst" ] ], "additional_components": [ "A5PJX7", "ENSBTAT00000019308", "E1BPI1", "ENSBTAT00000038826" ] }, "reaction_10052018": { "compartment": "compartment_70101", "id": "reaction_10052018", "reactome": "R-BTA-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10052015", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063578" ] }, "reaction_10052013": { "compartment": "compartment_917757", "id": "reaction_10052013", "reactome": "R-BTA-888577", "name": "Synthesis of GABA by GAD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10052010", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547", "F1N6X2", "ENSBTAT00000010598" ] }, "reaction_10051999": { "compartment": "compartment_70101", "id": "reaction_10051999", "reactome": "R-BTA-888572", "name": "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10051996", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547" ] }, "reaction_10051989": { "compartment": "compartment_5460", "id": "reaction_10051989", "reactome": "R-BTA-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_880046", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113536" ], "modifiers": [ [ "species_10051986", "catalyst" ] ], "additional_components": [ "E1BDP3", "ENSBTAT00000029203" ] }, "reaction_10033755": { "compartment": "compartment_5460", "id": "reaction_10033755", "reactome": "R-BTA-70609", "name": "glutamine + H2O => glutamate + NH4+ [GLS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113522", "species_113521" ], "products": [ "species_113561", "species_113552" ], "modifiers": [ [ "species_10033752", "catalyst" ] ], "additional_components": [ "E1BHZ6", "ENSBTAT00000012233" ] }, "reaction_10044461": { "compartment": "compartment_876", "id": "reaction_10044461", "reactome": "R-BTA-212642", "name": "L-Glutamine transport into neurons", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_212615", "species_74113" ], "products": [ "species_83910", "species_29472" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014749" ] }, "reaction_10044076": { "compartment": "compartment_984", "id": "reaction_10044076", "reactome": "R-BTA-210404", "name": "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_210382", "species_29804", "species_74113" ], "products": [ "species_74126", "species_29404", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ], [ "species_10044074", "inhibitor" ] ], "additional_components": [ "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455", "ENSBTAT00000028661" ] }, "reaction_10033746": { "compartment": "compartment_70101", "id": "reaction_10033746", "reactome": "R-BTA-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_31633" ], "products": [ "species_29372", "species_29370", "species_29472" ], "modifiers": [ [ "species_10033743", "catalyst" ] ], "additional_components": [ "P15103", "ENSBTAT00000074216" ] }, "reaction_10044086": { "compartment": "compartment_984", "id": "reaction_10044086", "reactome": "R-BTA-210439", "name": "glutamate uptake by astrocytes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382" ], "products": [ "species_29404" ], "modifiers": [ [ "species_10044083", "catalyst" ] ], "additional_components": [] }, "reaction_10054361": { "compartment": "compartment_876", "id": "reaction_10054361", "reactome": "R-BTA-975340", "name": "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054358", "catalyst" ] ], "additional_components": [ "species_428571", "A0A3Q1MA32", "ENSBTAT00000068615", "A0A3Q1MA22", "ENSBTAT00000069238", "F1MHX4", "ENSBTAT00000015688", "Q08E50", "ENSBTAT00000080524", "E1BE96", "ENSBTAT00000017637", "P08219", "ENSBTAT00000009483", "P08220", "ENSBTAT00000023711", "E1BJH4", "ENSBTAT00000060999" ] }, "reaction_10054372": { "compartment": "compartment_876", "id": "reaction_10054372", "reactome": "R-BTA-975449", "name": "GABRR pentamers:GABA transports extracellular Cl- to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054369", "catalyst" ] ], "additional_components": [ "species_428571", "E1B988", "ENSBTAT00000001857" ] }, "reaction_10051085": { "compartment": "compartment_984", "id": "reaction_10051085", "reactome": "R-BTA-500708", "name": "GRIK3 homomer binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050486", "species_210382" ], "products": [ "species_10051083" ], "modifiers": [], "additional_components": [ "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022", "species_210382", "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022" ] }, "reaction_10091067": { "compartment": "compartment_70101", "id": "reaction_10091067", "reactome": "R-BTA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091060", "species_113592" ], "products": [ "species_29370", "species_10091064" ], "modifiers": [ [ "species_10091060", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10091075": { "compartment": "compartment_70101", "id": "reaction_10091075", "reactome": "R-BTA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091071", "species_10037002" ], "products": [ "species_10091073" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010230", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "F6RXS3", "ENSBTAT00000010230" ] }, "reaction_10090547": { "compartment": "compartment_7660", "id": "reaction_10090547", "reactome": "R-BTA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090537" ], "products": [ "species_10090545" ], "modifiers": [], "additional_components": [ "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174" ] }, "reaction_10054318": { "compartment": "compartment_876", "id": "reaction_10054318", "reactome": "R-BTA-975311", "name": "HTR3 pentamers:5HT transport Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10054315", "catalyst" ] ], "additional_components": [ "G3N1Q1", "ENSBTAT00000062928", "F1N4Y2", "ENSBTAT00000014292", "E1BAL4", "ENSBTAT00000056946", "F1N5G0", "ENSBTAT00000055354", "G5E5J6", "ENSBTAT00000022113", "species_209914" ] }, "reaction_10091521": { "compartment": "compartment_876", "id": "reaction_10091521", "reactome": "R-BTA-9648983", "name": "HTR3A pentamer:5HT transports Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10091518", "catalyst" ] ], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10091525": { "compartment": "compartment_876", "id": "reaction_10091525", "reactome": "R-BTA-9649108", "name": "HTR3A pentamer binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091523", "species_114523" ], "products": [ "species_10091518" ], "modifiers": [], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10051521": { "compartment": "compartment_70101", "id": "reaction_10051521", "reactome": "R-BTA-629595", "name": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051518", "catalyst" ] ], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051523": { "compartment": "compartment_984", "id": "reaction_10051523", "reactome": "R-BTA-629596", "name": "Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051516", "species_372533" ], "products": [ "species_10051518" ], "modifiers": [], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051498": { "compartment": "compartment_876", "id": "reaction_10051498", "reactome": "R-BTA-622326", "name": "Activation of highly calcium permeable nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051495", "catalyst" ] ], "additional_components": [ "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10051525": { "compartment": "compartment_984", "id": "reaction_10051525", "reactome": "R-BTA-629599", "name": "Binding of acetylcholine to highly calcium permeable acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051493", "species_372533" ], "products": [ "species_10051495" ], "modifiers": [], "additional_components": [ "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679", "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10065894": { "compartment": "compartment_876", "id": "reaction_10065894", "reactome": "R-BTA-2559456", "name": "TIRAP binds PIP2-rich regions in the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065890", "species_179856" ], "products": [ "species_10065892" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070781", "species_6810412", "A0A3Q1M4J2", "ENSBTAT00000070781" ] }, "reaction_10039217": { "compartment": "compartment_984", "id": "reaction_10039217", "reactome": "R-BTA-166015", "name": "Association of LBP with LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10039213" ], "products": [ "species_10039215" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_166005" ] }, "reaction_10039560": { "compartment": "compartment_70101", "id": "reaction_10039560", "reactome": "R-BTA-168933", "name": "Dimerization of phosphorylated IRF3/IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039558" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10040197": { "compartment": "compartment_70101", "id": "reaction_10040197", "reactome": "R-BTA-177671", "name": "Dimerized phospho-IRF3/IRF7 is transported to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039558" ], "products": [ "species_10040195" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10085369": { "compartment": "compartment_984", "id": "reaction_10085369", "reactome": "R-BTA-8869683", "name": "oxPL binds LBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2186967", "species_10039213" ], "products": [ "species_10085367" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_2186967" ] }, "reaction_10081506": { "compartment": "compartment_984", "id": "reaction_10081506", "reactome": "R-BTA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081502", "species_181015" ], "products": [ "species_10081504" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_181015", "P10103", "ENSBTAT00000024094" ] }, "reaction_10081510": { "compartment": "compartment_984", "id": "reaction_10081510", "reactome": "R-BTA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10081502" ], "products": [ "species_10081508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_166005", "P10103", "ENSBTAT00000024094" ] }, "reaction_10060783": { "compartment": "compartment_17957", "id": "reaction_10060783", "reactome": "R-BTA-1678944", "name": "Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060771" ], "products": [ "species_10060769", "species_10060751", "species_211606", "species_10060763" ], "modifiers": [], "additional_components": [ "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592", "Q95M18", "ENSBTAT00000004364", "A0A3Q1MK24", "ENSBTAT00000079344", "ENSBTAT00000074388" ] }, "reaction_10060785": { "compartment": "compartment_17957", "id": "reaction_10060785", "reactome": "R-BTA-1678998", "name": "Endosomal TLRs pass through the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060757" ], "products": [ "species_10060781" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10060773": { "compartment": "compartment_17957", "id": "reaction_10060773", "reactome": "R-BTA-1678923", "name": "TLR folding by chaperones GP96 and CNPY3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060769", "species_211579", "species_10060749", "species_10060763" ], "products": [ "species_10060771" ], "modifiers": [], "additional_components": [ "Q95M18", "ENSBTAT00000004364", "ENSBTAT00000079344", "ENSBTAT00000074388", "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592" ] }, "reaction_10060759": { "compartment": "compartment_12045", "id": "reaction_10060759", "reactome": "R-BTA-1678921", "name": "Full-length TLR3/7/8/9 binds to UNC93B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060755", "species_10060751" ], "products": [ "species_10060757" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10091739": { "compartment": "compartment_70101", "id": "reaction_10091739", "reactome": "R-BTA-9679029", "name": "C-ter TLR7 dimer binds HCQ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091735", "species_9678628" ], "products": [ "species_10091737" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344" ] }, "reaction_10066168": { "compartment": "compartment_876", "id": "reaction_10066168", "reactome": "R-BTA-2730900", "name": "Activation of TAK1 complex bound to pUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066165", "species_113592" ], "products": [ "species_10066165", "species_29370" ], "modifiers": [ [ "species_10066165", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866" ] }, "reaction_10066059": { "compartment": "compartment_70101", "id": "reaction_10066059", "reactome": "R-BTA-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10066057" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066141": { "compartment": "compartment_876", "id": "reaction_10066141", "reactome": "R-BTA-2730864", "name": "Recruitment of TRAF6 to CBM complex by binding to MALT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066131", "species_10039473" ], "products": [ "species_10066139" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066172": { "compartment": "compartment_876", "id": "reaction_10066172", "reactome": "R-BTA-2730902", "name": "Oligomerization of p-CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066124", "species_10066109" ], "products": [ "species_10066170" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10066127": { "compartment": "compartment_876", "id": "reaction_10066127", "reactome": "R-BTA-2730863", "name": "Phosphorylation of CARMA1 by PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066122", "species_10066057" ], "products": [ "species_29370", "species_10066124" ], "modifiers": [ [ "species_10066057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066147": { "compartment": "compartment_876", "id": "reaction_10066147", "reactome": "R-BTA-2730882", "name": "Phosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043223", "species_113592" ], "products": [ "species_10043202", "species_29370" ], "modifiers": [ [ "species_10065638", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066180": { "compartment": "compartment_876", "id": "reaction_10066180", "reactome": "R-BTA-2730903", "name": "Oligomerization of TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10066139" ], "products": [ "species_10066178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066120": { "compartment": "compartment_876", "id": "reaction_10066120", "reactome": "R-BTA-2730862", "name": "Autophosphorylation of LYN kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066117", "species_113592" ], "products": [ "species_29370", "species_10065617" ], "modifiers": [ [ "species_10066117", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000075171", "ENSBTAT00000075171" ] }, "reaction_10066065": { "compartment": "compartment_876", "id": "reaction_10066065", "reactome": "R-BTA-2730841", "name": "Phosphorylation and activation of VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066061" ], "products": [ "species_29370", "species_10066063" ], "modifiers": [ [ "species_179838", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MQP9", "ENSBTAT00000086853" ] }, "reaction_10066082": { "compartment": "compartment_70101", "id": "reaction_10066082", "reactome": "R-BTA-2730844", "name": "Interaction of GRB2:SOS complex with p-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065484" ], "products": [ "species_10065486" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10066151": { "compartment": "compartment_876", "id": "reaction_10066151", "reactome": "R-BTA-2730886", "name": "Phosphorylation of SHC by SYK kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066149", "species_113592" ], "products": [ "species_29370", "species_10065484" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075224", "ENSBTAT00000075224", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066080": { "compartment": "compartment_876", "id": "reaction_10066080", "reactome": "R-BTA-2730842", "name": "PI3K associates with phosphorylated GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10066076" ], "products": [ "species_10066078" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10066144": { "compartment": "compartment_876", "id": "reaction_10066144", "reactome": "R-BTA-2730870", "name": "Phosphorylation of PIP2 to PIP3 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10066078", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065642": { "compartment": "compartment_876", "id": "reaction_10065642", "reactome": "R-BTA-2454240", "name": "Recruitment of SYK to p-FCERI gamma subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065638", "species_10037584" ], "products": [ "species_10065640" ], "modifiers": [], "additional_components": [ "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066094": { "compartment": "compartment_70101", "id": "reaction_10066094", "reactome": "R-BTA-2730847", "name": "Hydrolysis of PIP2 by PLCG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10066091", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383", "E1BKA6", "ENSBTAT00000020161", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10066052": { "compartment": "compartment_876", "id": "reaction_10066052", "reactome": "R-BTA-2730833", "name": "Phosphorylation of TEC kinases by p-SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066042" ], "products": [ "species_29370", "species_10066047" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "species_179838", "F1MSH3", "ENSBTAT00000046704", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066102": { "compartment": "compartment_876", "id": "reaction_10066102", "reactome": "R-BTA-2730858", "name": "Autophosphorylation of BTK/ITK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066047" ], "products": [ "species_10066099", "species_29370" ], "modifiers": [ [ "species_10066047", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10081085": { "compartment": "compartment_6800424", "id": "reaction_10081085", "reactome": "R-BTA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081071" ], "products": [ "species_10081083" ], "modifiers": [], "additional_components": [ "A0A3Q1LQX2", "ENSBTAT00000078403", "Q05204", "ENSBTAT00000045121", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1N8P4", "ENSBTAT00000066443", "F1MAU4", "ENSBTAT00000047906", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MS24", "ENSBTAT00000075240", "P61285", "ENSBTAT00000081563", "A7YWC4", "ENSBTAT00000012676", "P61585", "ENSBTAT00000005600", "G3N3S2", "ENSBTAT00000064122", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3S5ZPJ1", "ENSBTAT00000017459", "F1MIW8", "ENSBTAT00000018382", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M893", "ENSBTAT00000074148", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1LWC4", "ENSBTAT00000077476", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "F6PZJ9", "ENSBTAT00000084844", "E1BAJ4", "ENSBTAT00000013713", "Q9BDR7", "ENSBTAT00000034054", "A2VDP5", "ENSBTAT00000004547", "A2VDL2", "ENSBTAT00000042889", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "E1B6Z4", "ENSBTAT00000026429", "E1BHT5", "ENSBTAT00000020277", "A5PJK0", "ENSBTAT00000001458", "G5E5S0", "ENSBTAT00000028846", "Q1RMS1", "ENSBTAT00000000367", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1LMZ3", "ENSBTAT00000069125", "A0JN39", "ENSBTAT00000008616", "E1B876", "ENSBTAT00000047448", "Q3LUH2", "ENSBTAT00000032346", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "E1BDF5", "ENSBTAT00000049662", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A7YWC4", "ENSBTAT00000012676", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "Q05204", "ENSBTAT00000045121", "A0JN39", "ENSBTAT00000008616", "A0A3Q1LMZ3", "ENSBTAT00000069125", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MS24", "ENSBTAT00000075240", "A5PJK0", "ENSBTAT00000001458", "Q1RMS1", "ENSBTAT00000000367", "E1B876", "ENSBTAT00000047448", "A2VDP5", "ENSBTAT00000004547", "E1BD53", "ENSBTAT00000035679", "A0A3S5ZPJ1", "ENSBTAT00000017459", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LWC4", "ENSBTAT00000077476", "P61585", "ENSBTAT00000005600", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1N8P4", "ENSBTAT00000066443", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BCF4", "ENSBTAT00000012484", "E1BDF5", "ENSBTAT00000049662", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "F6PZJ9", "ENSBTAT00000084844", "Q9BDR7", "ENSBTAT00000034054", "F1MIW8", "ENSBTAT00000018382", "Q9MYM4", "ENSBTAT00000021325", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1M893", "ENSBTAT00000074148", "F1MAU4", "ENSBTAT00000047906", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "E1BGJ5", "ENSBTAT00000005511" ] }, "reaction_10079949": { "compartment": "compartment_1462052", "id": "reaction_10079949", "reactome": "R-BTA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079839" ], "products": [ "species_10079947" ], "modifiers": [], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A452DI43", "ENSBTAT00000008107", "F1MRP0", "ENSBTAT00000000876", "Q5E987", "ENSBTAT00000027507", "Q0II59", "ENSBTAT00000024203", "P68401", "ENSBTAT00000007398", "Q3SZ62", "ENSBTAT00000032937", "Q3ZCI9", "ENSBTAT00000018917", "P28782", "ENSBTAT00000066555", "E1BI70", "ENSBTAT00000027682", "P79105", "ENSBTAT00000063314", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MFC3", "ENSBTAT00000069599", "A5PKG9", "ENSBTAT00000078914", "Q3T0A3", "ENSBTAT00000063284", "P12763", "ENSBTAT00000000673", "F6QEU6", "ENSBTAT00000007589", "A1A4J1", "ENSBTAT00000056305", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "P10103", "ENSBTAT00000024094", "Q17QP9", "ENSBTAT00000046166", "F1MWU9", "ENSBTAT00000057500", "Q2KJ46", "ENSBTAT00000028608", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F1MHT1", "ENSBTAT00000008518", "Q5E9F9", "ENSBTAT00000065774", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q2KJ25", "ENSBTAT00000003145", "A0A452DJA8", "ENSBTAT00000016346", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A140T8A5", "ENSBTAT00000027348", "A6QQL9", "ENSBTAT00000019085", "F1MWE0", "ENSBTAT00000028983", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "P62935", "ENSBTAT00000015924", "A0A452DIT4", "ENSBTAT00000023325", "Q58DK5", "ENSBTAT00000000315", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1LXA9", "ENSBTAT00000077815", "G3MXC8", "ENSBTAT00000064442", "A0A452DIE3", "ENSBTAT00000000841", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "F1MWE0", "ENSBTAT00000028983", "Q5E9F9", "ENSBTAT00000065774", "Q2KJ25", "ENSBTAT00000003145", "Q3ZCI9", "ENSBTAT00000018917", "F1MRP0", "ENSBTAT00000000876", "Q0II59", "ENSBTAT00000024203", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "P28782", "ENSBTAT00000066555", "P79105", "ENSBTAT00000063314", "A0A3Q1MFC3", "ENSBTAT00000069599", "P68401", "ENSBTAT00000007398", "A5PKG9", "ENSBTAT00000078914", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A452DIE3", "ENSBTAT00000000841", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MBA7", "ENSBTAT00000013758", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "P12763", "ENSBTAT00000000673", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "F1MHT1", "ENSBTAT00000008518", "Q2KJ46", "ENSBTAT00000028608", "Q17QP9", "ENSBTAT00000046166" ] }, "reaction_10080063": { "compartment": "compartment_6799371", "id": "reaction_10080063", "reactome": "R-BTA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080039" ], "products": [ "species_10080061" ], "modifiers": [], "additional_components": [ "A0A3Q1LRA9", "ENSBTAT00000080425", "G3MWP1", "ENSBTAT00000064480", "P33046", "ENSBTAT00000044788", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BPI3", "ENSBTAT00000026661", "Q3ZCL0", "ENSBTAT00000076131", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q2LGB5", "ENSBTAT00000010835", "E1BCU6", "ENSBTAT00000027423", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "A0A3Q1M2J3", "ENSBTAT00000079464", "Q5GN72", "ENSBTAT00000022991", "E1B8Y2", "ENSBTAP00000001395", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZC41", "ENSBTAT00000024335", "F6RMV5", "ENSBTAT00000003618", "G3N0J0", "ENSBTAT00000063400", "E1B6Z6", "ENSBTAT00000018806", "F1MVJ8", "ENSBTAT00000030920", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "E1BFV0", "ENSBTAT00000008650", "P24627", "ENSBTAT00000001704", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F1MRP0", "ENSBTAT00000000876", "A0A3Q1LWX5", "ENSBTAT00000081739", "P80189", "ENSBTAT00000038266", "A0A3Q1MD51", "ENSBTAT00000087110", "F1MW13", "ENSBTAT00000009806", "Q3MHQ1", "ENSBTAT00000007133", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "G3MWP1", "ENSBTAT00000064480", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "A4IF76", "ENSBTAT00000074688", "E1BPI3", "ENSBTAT00000026661", "Q3MHQ1", "ENSBTAT00000007133", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "Q0VCN9", "ENSBTAT00000027602", "F1MRP0", "ENSBTAT00000000876", "Q2LGB5", "ENSBTAT00000010835", "A7YWG4", "ENSBTAT00000009917", "A0A3Q1LRA9", "ENSBTAT00000080425", "E1B6Z6", "ENSBTAT00000018806", "F6RMV5", "ENSBTAT00000003618", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MW13", "ENSBTAT00000009806", "Q3ZCL0", "ENSBTAT00000076131", "A0A3Q1LWX5", "ENSBTAT00000081739", "E1B8Y2", "ENSBTAP00000001395", "E1BFV0", "ENSBTAT00000008650", "Q3ZC41", "ENSBTAT00000024335", "P24627", "ENSBTAT00000001704", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10080719": { "compartment": "compartment_6799351", "id": "reaction_10080719", "reactome": "R-BTA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080687" ], "products": [ "species_10080717" ], "modifiers": [], "additional_components": [ "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MIE9", "ENSBTAT00000079230", "A2VDL2", "ENSBTAT00000042889", "Q29455", "ENSBTAT00000070817", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1MP64", "ENSBTAT00000068539", "Q0VD15", "ENSBTAT00000018402", "A0A3Q1M0A2", "ENSBTAT00000074088", "A0A3Q1LNV7", "ENSBTAT00000083870", "A6H797", "ENSBTAT00000026715", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MFT3", "ENSBTAT00000084806", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BFE2", "ENSBTAT00000020345", "F1N1F5", "ENSBTAT00000021843", "O46521", "ENSBTAT00000067849", "Q58DM3", "ENSBTAT00000008479", "E1BNL9", "ENSBTAT00000027255", "E1BHT5", "ENSBTAT00000020277", "F1N4H1", "ENSBTAT00000055016", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1MIW3", "ENSBTAT00000037423", "P26201", "ENSBTAT00000080828", "A0A3Q1M6K1", "ENSBTAT00000081330", "A0A3Q1MED5", "ENSBTAT00000085048", "P62833", "ENSBTAT00000068678", "F1ME65", "ENSBTAT00000015804", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1M4C7", "ENSBTAT00000078122", "A8E4P3", "ENSBTAT00000052503", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NF89", "ENSBTAT00000076616", "F1MTY9", "ENSBTAT00000047056", "F1MN89", "ENSBTAT00000008168", "F1N680", "ENSBTAT00000026019", "F1MLP3", "ENSBTAT00000008097", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1MQ27", "ENSBTAT00000069303", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q1JPA0", "ENSBTAT00000076578", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "Q32PA1", "ENSBTAT00000002967", "F1N3R7", "ENSBTAT00000026770", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1M288", "ENSBTAT00000085751", "Q6QRN7", "ENSBTAT00000005137", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "P62833", "ENSBTAT00000068678", "Q6QRN7", "ENSBTAT00000005137", "A6H797", "ENSBTAT00000026715", "A0A3Q1M0A2", "ENSBTAT00000074088", "A8E4P3", "ENSBTAT00000052503", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1NF89", "ENSBTAT00000076616", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "F1ME65", "ENSBTAT00000015804", "F1N1F5", "ENSBTAT00000021843", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "Q0VD15", "ENSBTAT00000018402", "Q58DM3", "ENSBTAT00000008479", "Q29455", "ENSBTAT00000070817", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "F1N680", "ENSBTAT00000026019", "Q2KI97", "ENSBTAT00000020710", "F1MIW3", "ENSBTAT00000037423", "F1N3R7", "ENSBTAT00000026770", "F1MLP3", "ENSBTAT00000008097", "F1N4H1", "ENSBTAT00000055016", "F1MZS9", "ENSBTAT00000035230", "P26201", "ENSBTAT00000080828", "F1MTY9", "ENSBTAT00000047056", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1MN89", "ENSBTAT00000008168", "A0A3Q1M2M7", "ENSBTAT00000073921", "A0A3Q1M4C7", "ENSBTAT00000078122", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1M6K1", "ENSBTAT00000081330", "Q17QQ1", "ENSBTAT00000047833", "O46521", "ENSBTAT00000067849", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1MIE9", "ENSBTAT00000079230", "Q1JPA0", "ENSBTAT00000076578", "E1BHT5", "ENSBTAT00000020277", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1M288", "ENSBTAT00000085751", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10079391": { "compartment": "compartment_6800173", "id": "reaction_10079391", "reactome": "R-BTA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079319" ], "products": [ "species_10079389" ], "modifiers": [], "additional_components": [ "A7YWG4", "ENSBTAT00000009917", "Q0VCN9", "ENSBTAT00000027602", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LMG1", "ENSBTAT00000083687", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5W1C4", "ENSBTAT00000080090", "Q5GN72", "ENSBTAT00000022991", "F1MVJ8", "ENSBTAT00000030920", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "G3N0J0", "ENSBTAT00000063400", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A140T831", "ENSBTAT00000000683", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1M739", "ENSBTAT00000077529", "A0A452DIT4", "ENSBTAT00000023325", "E1B8Y2", "ENSBTAP00000001395", "A7YWU9", "ENSBTAT00000028731", "P25326", "ENSBTAT00000022774", "P24627", "ENSBTAT00000001704", "E1BCU6", "ENSBTAT00000027423", "P01035", "ENSBTAT00000000790", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P33046", "ENSBTAT00000044788", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q3ZBE7", "ENSBTAT00000032525", "P80189", "ENSBTAT00000038266", "A0A140T8A5", "ENSBTAT00000027348", "A4IF76", "ENSBTAT00000074688", "Q5EA55", "ENSBTAT00000069302", "Q3ZCL0", "ENSBTAT00000076131", "P02070", "ENSBTAT00000057323", "A0A3Q1M2R9", "ENSBTAT00000085538", "Q5EA55", "ENSBTAT00000069302", "A7YWU9", "ENSBTAT00000028731", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A140T8A5", "ENSBTAT00000027348", "Q5W1C4", "ENSBTAT00000080090", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "P25326", "ENSBTAT00000022774", "A0A452DIT4", "ENSBTAT00000023325", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MGS0", "ENSBTAT00000074118", "P01035", "ENSBTAT00000000790", "A0A140T831", "ENSBTAT00000000683", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1B8Y2", "ENSBTAP00000001395", "Q3ZCL0", "ENSBTAT00000076131", "P24627", "ENSBTAT00000001704", "P02070", "ENSBTAT00000057323", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZBE7", "ENSBTAT00000032525", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10079199": { "compartment": "compartment_876", "id": "reaction_10079199", "reactome": "R-BTA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079131" ], "products": [ "species_10079197" ], "modifiers": [], "additional_components": [ "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1NF89", "ENSBTAT00000076616", "Q0VD15", "ENSBTAT00000018402", "Q9TTY5", "ENSBTAT00000038757", "A0JN39", "ENSBTAT00000008616", "A0A452DIB1", "ENSBTAT00000013018", "P08037", "ENSBTAT00000020286", "F1MDR7", "ENSBTAT00000003865", "A6QLS9", "ENSBTAT00000001303", "E1BK38", "ENSBTAT00000061018", "E1BCF4", "ENSBTAT00000012484", "P11023", "ENSBTAT00000014062", "A0A3Q1MS24", "ENSBTAT00000075240", "Q08DC2", "ENSBTAT00000075871", "A7YWC4", "ENSBTAT00000012676", "F1MNI4", "ENSBTAT00000018777", "F6PZJ9", "ENSBTAT00000084844", "F1MCK4", "ENSBTAT00000054453", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1LZT3", "ENSBTAT00000069265", "Q673L2", "ENSBTAT00000027807", "Q2KI99", "ENSBTAT00000071484", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1MHJ9", "ENSBTAT00000086833", "E1BI37", "ENSBTAT00000035878", "Q3LUH2", "ENSBTAT00000032346", "F1MHH9", "ENSBTAT00000029116", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N0T3", "ENSBTAT00000023242", "E1BPL8", "ENSBTAT00000002681", "E1B876", "ENSBTAT00000047448", "P61585", "ENSBTAT00000005600", "E1BD53", "ENSBTAT00000035679", "Q1RMI2", "ENSBTAT00000000453", "F1MIE6", "ENSBTAT00000037678", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1MB09", "ENSBTAT00000068383", "A5PJK0", "ENSBTAT00000001458", "E1BGJ5", "ENSBTAT00000005511", "Q1JPA0", "ENSBTAT00000076578", "F1MTR1", "ENSBTAT00000001190", "F1MHH9", "ENSBTAT00000029116", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A6QLS9", "ENSBTAT00000001303", "F1MTR1", "ENSBTAT00000001190", "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "Q673L2", "ENSBTAT00000027807", "F1MCK4", "ENSBTAT00000054453", "F6PZJ9", "ENSBTAT00000084844", "P11023", "ENSBTAT00000014062", "Q08DC2", "ENSBTAT00000075871", "A0A452DIB1", "ENSBTAT00000013018", "E1BPL8", "ENSBTAT00000002681", "A0A3Q1NF89", "ENSBTAT00000076616", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1MNI4", "ENSBTAT00000018777", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MB09", "ENSBTAT00000068383", "A0A3Q1NNM6", "ENSBTAT00000081334", "A7YWC4", "ENSBTAT00000012676", "Q0VD15", "ENSBTAT00000018402", "A0JN39", "ENSBTAT00000008616", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1MJS9", "ENSBTAT00000013320", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1MS24", "ENSBTAT00000075240", "Q1RMI2", "ENSBTAT00000000453", "E1BI37", "ENSBTAT00000035878", "A5PJK0", "ENSBTAT00000001458", "E1B876", "ENSBTAT00000047448", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "E1BK38", "ENSBTAT00000061018", "P61585", "ENSBTAT00000005600", "Q2KI99", "ENSBTAT00000071484", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BCF4", "ENSBTAT00000012484", "F1MIE6", "ENSBTAT00000037678", "A0A3Q1M0R0", "ENSBTAT00000081916", "P08037", "ENSBTAT00000020286", "Q1JPA0", "ENSBTAT00000076578", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10078929": { "compartment": "compartment_6798757", "id": "reaction_10078929", "reactome": "R-BTA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078881" ], "products": [ "species_10078927" ], "modifiers": [], "additional_components": [ "A0A3Q1MCZ8", "ENSBTAT00000067584", "P61223", "ENSBTAT00000019575", "Q2KIW2", "ENSBTAT00000000146", "Q02827", "ENSBTAT00000024209", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1MDC6", "ENSBTAT00000075241", "F1N3T5", "ENSBTAT00000021761", "A8E4P3", "ENSBTAT00000052503", "F1MAU4", "ENSBTAT00000047906", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BK38", "ENSBTAT00000061018", "Q3T0Y8", "ENSBTAT00000033040", "G3MY77", "ENSBTAT00000065645", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q29455", "ENSBTAT00000070817", "A4IFF5", "ENSBTAT00000026308", "F1ME65", "ENSBTAT00000015804", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1N680", "ENSBTAT00000026019", "A5PJY9", "ENSBTAT00000020644", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1NHB1", "ENSBTAT00000080189", "Q05204", "ENSBTAT00000045121", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q0II86", "ENSBTAT00000027666", "Q9XSK2", "ENSBTAT00000015829", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "P08037", "ENSBTAT00000020286", "A0A3Q1MDS4", "ENSBTAT00000073232", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q3T0Y8", "ENSBTAT00000033040", "F1MAU4", "ENSBTAT00000047906", "F1ME65", "ENSBTAT00000015804", "Q9MYM4", "ENSBTAT00000021325", "P61223", "ENSBTAT00000019575", "A0A3Q1N0X5", "ENSBTAT00000068372", "A0A3Q1MDC6", "ENSBTAT00000075241", "A8E4P3", "ENSBTAT00000052503", "P08037", "ENSBTAT00000020286", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "E1BI37", "ENSBTAT00000035878", "Q2KIW2", "ENSBTAT00000000146", "A0A3Q1NHB1", "ENSBTAT00000080189", "F1N3T5", "ENSBTAT00000021761", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1N8P4", "ENSBTAT00000066443", "G3MY77", "ENSBTAT00000065645", "Q9XSK2", "ENSBTAT00000015829", "E1BK38", "ENSBTAT00000061018", "A4IFF5", "ENSBTAT00000026308", "Q02827", "ENSBTAT00000024209", "A0A3Q1MDS4", "ENSBTAT00000073232", "Q0II86", "ENSBTAT00000027666", "F1N680", "ENSBTAT00000026019", "F1MDR7", "ENSBTAT00000003865", "Q29455", "ENSBTAT00000070817", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q05204", "ENSBTAT00000045121", "F1MTK4", "ENSBTAT00000001250", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10081265": { "compartment": "compartment_984", "id": "reaction_10081265", "reactome": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081245" ], "products": [ "species_10081263" ], "modifiers": [], "additional_components": [ "A0A3Q1LTT9", "ENSBTAT00000073013", "Q5E9F9", "ENSBTAT00000065774", "Q3SWY3", "ENSBTAT00000025179", "F1MWE0", "ENSBTAT00000028983", "Q3SZ62", "ENSBTAT00000032937", "F1MHT1", "ENSBTAT00000008518", "A0A452DI43", "ENSBTAT00000008107", "F1MNS8", "ENSBTAT00000061310", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "Q2KJ46", "ENSBTAT00000028608", "Q3T0A3", "ENSBTAT00000063284", "A0A140T8A5", "ENSBTAT00000027348", "P34955", "ENSBTAT00000072441", "P02070", "ENSBTAT00000057323", "Q5W1C4", "ENSBTAT00000080090", "Q3ZBE7", "ENSBTAT00000032525", "P68401", "ENSBTAT00000007398", "A1A4J1", "ENSBTAT00000056305", "Q3ZCI9", "ENSBTAT00000018917", "E1BFV0", "ENSBTAT00000008650", "G3N0V2", "ENSBTAT00000065029", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "Q29RY7", "ENSBTAT00000012815", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A3Q1MD51", "ENSBTAT00000087110", "A0A452DJA8", "ENSBTAT00000016346", "A6QQL9", "ENSBTAT00000019085", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "Q27975", "ENSBTAT00000017500", "P01035", "ENSBTAT00000000790", "P62935", "ENSBTAT00000015924", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "A0A452DIT4", "ENSBTAT00000023325", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "Q2KJ25", "ENSBTAT00000003145", "Q17QP9", "ENSBTAT00000046166", "A4IFQ6", "ENSBTAT00000018403", "P07688", "ENSBTAT00000036795", "P25326", "ENSBTAT00000022774", "E1BB52", "ENSBTAT00000002003", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A452DJ01", "ENSBTAT00000011678", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1LPS7", "ENSBTAT00000084564", "E1BA23", "ENSBTAT00000021018", "F1MMD5", "ENSBTAT00000008020", "F1MXZ0", "ENSBTAT00000023218", "A3KMY8", "ENSBTAT00000000941", "A6QLZ3", "ENSBTAT00000010988", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q2KJ25", "ENSBTAT00000003145", "F6RMV5", "ENSBTAT00000003618", "Q3ZCI9", "ENSBTAT00000018917", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "P01035", "ENSBTAT00000000790", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1MGS0", "ENSBTAT00000074118", "A6QLZ3", "ENSBTAT00000010988", "P68401", "ENSBTAT00000007398", "A3KMY8", "ENSBTAT00000000941", "A0A3Q1M2J3", "ENSBTAT00000079464", "F1MNS8", "ENSBTAT00000061310", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "E1BFV0", "ENSBTAT00000008650", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A3Q1M5Y2", "ENSBTAT00000084883", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "P34955", "ENSBTAT00000072441", "P25326", "ENSBTAT00000022774", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LXA9", "ENSBTAT00000077815", "Q58DK5", "ENSBTAT00000000315", "A0A3Q1MD51", "ENSBTAT00000087110", "A5D984", "ENSBTAT00000047412", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "Q5W1C4", "ENSBTAT00000080090", "Q29RY7", "ENSBTAT00000012815", "Q5E9F9", "ENSBTAT00000065774", "Q27975", "ENSBTAT00000017500", "F1MWE0", "ENSBTAT00000028983", "G3N0V2", "ENSBTAT00000065029", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "A0A452DJ01", "ENSBTAT00000011678", "F1MHT1", "ENSBTAT00000008518", "P02070", "ENSBTAT00000057323", "A4IFQ6", "ENSBTAT00000018403", "Q2KJ46", "ENSBTAT00000028608", "Q3ZBE7", "ENSBTAT00000032525", "P07688", "ENSBTAT00000036795", "Q17QP9", "ENSBTAT00000046166", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10080435": { "compartment": "compartment_1470028", "id": "reaction_10080435", "reactome": "R-BTA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080307" ], "products": [ "species_10080433" ], "modifiers": [], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1MGY9", "ENSBTAT00000022716", "A0A3Q1MPJ7", "ENSBTAT00000067144", "H7BWW2", "ENSBTAT00000048411", "F1MU84", "ENSBTAT00000006001", "A7MBA2", "ENSBTAT00000006754", "A6QPT4", "ENSBTAT00000067752", "O77834", "ENSBTAT00000006383", "E1BI70", "ENSBTAT00000027682", "P80189", "ENSBTAT00000038266", "A0A3Q1LYV0", "ENSBTAT00000070714", "Q5GN72", "ENSBTAT00000022991", "A6QLB7", "ENSBTAT00000017775", "G3MWP1", "ENSBTAT00000064480", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A3Q1MRR6", "ENSBTAT00000078659", "A7YWU9", "ENSBTAT00000028731", "Q3MHM5", "ENSBTAT00000074704", "Q17QI1", "ENSBTAT00000065281", "A0A3Q1LUG9", "ENSBTAT00000076880", "E1BPI3", "ENSBTAT00000026661", "O46415", "ENSBTAT00000009965", "Q2LGB5", "ENSBTAT00000010835", "F1N7I6", "ENSBTAT00000024550", "F1N1V6", "ENSBTAT00000005121", "F1MU24", "ENSBTAT00000006069", "Q2KJD0", "ENSBTAT00000009158", "A0A3Q1LQA6", "ENSBTAT00000072426", "E1BFP1", "ENSBTAT00000000304", "A7YWG4", "ENSBTAT00000009917", "Q29451", "ENSBTAT00000070599", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "E1BI28", "ENSBTAT00000029099", "E1BAD2", "ENSBTAT00000054741", "A0A452DJ87", "ENSBTAT00000039203", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1ML33", "ENSBTAT00000073654", "A0A3Q1LMW6", "ENSBTAT00000073103", "E1B8B5", "ENSBTAT00000053165", "A0A3Q1LTS9", "ENSBTAT00000068563", "F1MMS7", "ENSBTAT00000065330", "A0A3Q1LY36", "ENSBTAT00000068245", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LIW8", "ENSBTAT00000073870", "Q3ZCI9", "ENSBTAT00000018917", "P79345", "ENSBTAT00000029271", "F6QH17", "ENSBTAT00000026526", "F1MUP9", "ENSBTAT00000009715", "F1MGC2", "ENSBTAT00000036230", "G3N2H4", "ENSBTAT00000063121", "F6QIT9", "ENSBTAT00000019270", "A3KMY8", "ENSBTAT00000000941", "P04272", "ENSBTAT00000012655", "A0A3Q1MS42", "ENSBTAT00000074408", "Q2KJ64", "ENSBTAT00000016461", "F1N048", "ENSBTAT00000004411", "A6QLZ3", "ENSBTAT00000010988", "E1B725", "ENSBTAT00000025636", "Q2KIM0", "ENSBTAT00000042970", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "F1N5H2", "ENSBTAT00000002297", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "A0A3Q1LYV0", "ENSBTAT00000070714", "F1MXZ0", "ENSBTAT00000023218", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "F1MU84", "ENSBTAT00000006001", "F1MGY9", "ENSBTAT00000022716", "A6QLZ3", "ENSBTAT00000010988", "P04272", "ENSBTAT00000012655", "F1N5H2", "ENSBTAT00000002297", "E1BAD2", "ENSBTAT00000054741", "H7BWW2", "ENSBTAT00000048411", "A3KMY8", "ENSBTAT00000000941", "G3N2H4", "ENSBTAT00000063121", "E1BI28", "ENSBTAT00000029099", "A0A452DJ87", "ENSBTAT00000039203", "A0A3Q1MPJ7", "ENSBTAT00000067144", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LUG9", "ENSBTAT00000076880", "F6QH17", "ENSBTAT00000026526", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "F1MUP9", "ENSBTAT00000009715", "A0A3Q1ML33", "ENSBTAT00000073654", "E1B8B5", "ENSBTAT00000053165", "F1MMS7", "ENSBTAT00000065330", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1LMW6", "ENSBTAT00000073103", "A0A3Q1LTS9", "ENSBTAT00000068563", "A0A3Q1LY36", "ENSBTAT00000068245", "F1N1V6", "ENSBTAT00000005121", "Q3MHM5", "ENSBTAT00000074704", "Q2KJD0", "ENSBTAT00000009158", "Q17QI1", "ENSBTAT00000065281", "Q2KJ64", "ENSBTAT00000016461", "A7MBA2", "ENSBTAT00000006754", "O77834", "ENSBTAT00000006383", "Q2LGB5", "ENSBTAT00000010835", "Q2KIM0", "ENSBTAT00000042970", "A7YWU9", "ENSBTAT00000028731", "E1B725", "ENSBTAT00000025636", "A6QLB7", "ENSBTAT00000017775", "E1BPI3", "ENSBTAT00000026661", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "F6QIT9", "ENSBTAT00000019270", "F1N048", "ENSBTAT00000004411", "P80189", "ENSBTAT00000038266", "A0A3Q1MS42", "ENSBTAT00000074408", "G3MWP1", "ENSBTAT00000064480", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "Q29451", "ENSBTAT00000070599", "Q3ZCI9", "ENSBTAT00000018917", "A7YWG4", "ENSBTAT00000009917", "A6QPT4", "ENSBTAT00000067752", "F1MU24", "ENSBTAT00000006069", "F1N7I6", "ENSBTAT00000024550", "E1BFP1", "ENSBTAT00000000304", "A0A3Q1LQA6", "ENSBTAT00000072426", "A0A3Q1LIW8", "ENSBTAT00000073870", "F1MGC2", "ENSBTAT00000036230", "P79345", "ENSBTAT00000029271", "O46415", "ENSBTAT00000009965" ] }, "reaction_10079653": { "compartment": "compartment_6799713", "id": "reaction_10079653", "reactome": "R-BTA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079613" ], "products": [ "species_10079651" ], "modifiers": [], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230", "F1N0T3", "ENSBTAT00000023242", "E1BFE2", "ENSBTAT00000020345", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "Q9TTY5", "ENSBTAT00000038757", "Q58DM3", "ENSBTAT00000008479", "A0A3Q1MP64", "ENSBTAT00000068539", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "O46521", "ENSBTAT00000067849", "A8E4P3", "ENSBTAT00000052503", "P61285", "ENSBTAT00000081563", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1MED5", "ENSBTAT00000085048", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "G5E5N4", "ENSBTAT00000026431", "Q9MYM4", "ENSBTAT00000021325", "Q32LK2", "ENSBTAT00000022077", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "A0JN39", "ENSBTAT00000008616", "A2VDL2", "ENSBTAT00000042889", "G3X6D0", "ENSBTAT00000004058", "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A5D7R9", "ENSBTAT00000012897", "Q3ZBG1", "ENSBTAT00000023671", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1N4H1", "ENSBTAT00000055016", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1M2M7", "ENSBTAT00000073921", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MQ27", "ENSBTAT00000069303", "Q32PA1", "ENSBTAT00000002967", "G3N3S2", "ENSBTAT00000064122", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1LZT3", "ENSBTAT00000069265", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "A8E4P3", "ENSBTAT00000052503", "Q9BDR7", "ENSBTAT00000034054", "Q9MYM4", "ENSBTAT00000021325", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0JN39", "ENSBTAT00000008616", "Q58DM3", "ENSBTAT00000008479", "Q3LUH2", "ENSBTAT00000032346", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "Q2KI97", "ENSBTAT00000020710", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q3ZBG1", "ENSBTAT00000023671", "A5D7R9", "ENSBTAT00000012897", "O46521", "ENSBTAT00000067849", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "Q32LK2", "ENSBTAT00000022077", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1MIE9", "ENSBTAT00000079230", "E1BHT5", "ENSBTAT00000020277", "G3X6D0", "ENSBTAT00000004058", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1NDL5", "ENSBTAT00000086325", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10072392": { "compartment": "compartment_876", "id": "reaction_10072392", "reactome": "R-BTA-5621366", "name": "SYK binds to p-Y65,Y76-FCER1G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072358", "species_10037584" ], "products": [ "species_10072390" ], "modifiers": [], "additional_components": [ "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10072395": { "compartment": "compartment_876", "id": "reaction_10072395", "reactome": "R-BTA-5621370", "name": "SYK autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072390", "species_113592" ], "products": [ "species_29370", "species_10072360" ], "modifiers": [ [ "species_10072390", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10084636": { "compartment": "compartment_876", "id": "reaction_10084636", "reactome": "R-BTA-8858500", "name": "CLEC10A binds Tn-MUC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084632", "species_10084616" ], "products": [ "species_10084634" ], "modifiers": [], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000054378", "E1BJL5", "ENSBTAT00000054378", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897" ] }, "reaction_10072364": { "compartment": "compartment_876", "id": "reaction_10072364", "reactome": "R-BTA-5621347", "name": "PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072362" ], "products": [ "species_10072360", "species_10072008" ], "modifiers": [], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000074574" ] }, "reaction_10072383": { "compartment": "compartment_876", "id": "reaction_10072383", "reactome": "R-BTA-5621355", "name": "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072378" ], "products": [ "species_10072358", "species_29370" ], "modifiers": [ [ "species_10072380", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "CHEBI:28808", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10072388": { "compartment": "compartment_876", "id": "reaction_10072388", "reactome": "R-BTA-5621363", "name": "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072385" ], "products": [ "species_29370", "species_10072362" ], "modifiers": [ [ "species_10072385", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574" ] }, "reaction_10072374": { "compartment": "compartment_876", "id": "reaction_10072374", "reactome": "R-BTA-5621353", "name": "CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072370", "species_5621138" ], "products": [ "species_10072372" ], "modifiers": [], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016", "species_5621138", "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016" ] }, "reaction_10072057": { "compartment": "compartment_876", "id": "reaction_10072057", "reactome": "R-BTA-5607753", "name": "CARD9 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072055", "species_10071996" ], "products": [ "species_10071998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072011": { "compartment": "compartment_876", "id": "reaction_10072011", "reactome": "R-BTA-5607735", "name": "p-Y753,Y759-PLCG2 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10072008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10072045": { "compartment": "compartment_876", "id": "reaction_10072045", "reactome": "R-BTA-5607750", "name": "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072038", "species_113592" ], "products": [ "species_29370", "species_10072043" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "CHEBI:37671", "F1N2F3", "ENSBTAT00000085840", "F1N2F3", "ENSBTAT00000085840", "CHEBI:37671", "ENSBTAT00000011767" ] }, "reaction_10072061": { "compartment": "compartment_876", "id": "reaction_10072061", "reactome": "R-BTA-5607755", "name": "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072059" ], "products": [ "species_10072008" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10072015": { "compartment": "compartment_876", "id": "reaction_10072015", "reactome": "R-BTA-5607737", "name": "BCL10 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072000", "species_10043291" ], "products": [ "species_10072013" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072032": { "compartment": "compartment_876", "id": "reaction_10072032", "reactome": "R-BTA-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072004" ], "products": [ "species_10072019" ], "modifiers": [], "additional_components": [ "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072002": { "compartment": "compartment_876", "id": "reaction_10072002", "reactome": "R-BTA-5607733", "name": "BCL10 binds CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071998", "species_10043291" ], "products": [ "species_10072000" ], "modifiers": [], "additional_components": [ "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072053": { "compartment": "compartment_876", "id": "reaction_10072053", "reactome": "R-BTA-5607751", "name": "TRAF6 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072049", "species_10039473" ], "products": [ "species_10072051" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000021630", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10072006": { "compartment": "compartment_876", "id": "reaction_10072006", "reactome": "R-BTA-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070610", "species_112275" ], "products": [ "species_10072004" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072022": { "compartment": "compartment_876", "id": "reaction_10072022", "reactome": "R-BTA-5607740", "name": "PKC-delta phosphorylates CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072017" ], "products": [ "species_29370", "species_10071996" ], "modifiers": [ [ "species_10072019", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10054649": { "compartment": "compartment_876", "id": "reaction_10054649", "reactome": "R-BTA-977602", "name": "Complement factor I binds to MCP, CR1:C4b, C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054645", "species_10054492" ], "products": [ "species_10054647" ], "modifiers": [], "additional_components": [ "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10054494": { "compartment": "compartment_984", "id": "reaction_10054494", "reactome": "R-BTA-976801", "name": "Complement factor I complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054490", "species_10054488" ], "products": [ "species_10054492" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076236", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236" ] }, "reaction_10066238": { "compartment": "compartment_984", "id": "reaction_10066238", "reactome": "R-BTA-2855047", "name": "Hydrolysis of internal thioester in C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10039322" ], "products": [ "species_10066236" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019" ] }, "reaction_10090400": { "compartment": "compartment_984", "id": "reaction_10090400", "reactome": "R-BTA-9021306", "name": "C1-Inh binds and inactivates C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084018" ], "products": [ "species_10084063" ], "modifiers": [], "additional_components": [ "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "E1BMJ0", "ENSBTAT00000021638", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10055971": { "compartment": "compartment_876", "id": "reaction_10055971", "reactome": "R-BTA-1006169", "name": "Factor H binds host cell surface markers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006146", "species_10054484" ], "products": [ "species_10055969" ], "modifiers": [], "additional_components": [ "CHEBI:24505", "species_1006168", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "CHEBI:24505", "species_1006168" ] }, "reaction_10087797": { "compartment": "compartment_876", "id": "reaction_10087797", "reactome": "R-BTA-8951486", "name": "CD46 binds C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054643", "species_10054624" ], "products": [ "species_10054645" ], "modifiers": [], "additional_components": [ "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "ENSBTAT00000073079", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10084020": { "compartment": "compartment_984", "id": "reaction_10084020", "reactome": "R-BTA-8852266", "name": "C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039462", "species_10038209" ], "products": [ "species_10084018" ], "modifiers": [], "additional_components": [ "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "ENSBTAT00000021638", "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10054678": { "compartment": "compartment_876", "id": "reaction_10054678", "reactome": "R-BTA-977615", "name": "Factor I inactivates MCP/CR1-bound C4b/C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054647" ], "products": [ "species_10054675", "species_10054624", "species_10054657", "species_10054492" ], "modifiers": [ [ "species_10054647", "catalyst" ] ], "additional_components": [ "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "ENSBTAT00000073079", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10039465": { "compartment": "compartment_984", "id": "reaction_10039465", "reactome": "R-BTA-166753", "name": "Conversion of C4 into C4a and C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039302" ], "products": [ "species_10039310", "species_10039322" ], "modifiers": [ [ "species_10039462", "catalyst" ] ], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10039778": { "compartment": "compartment_984", "id": "reaction_10039778", "reactome": "R-BTA-173626", "name": "Activation of C1r", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039759" ], "products": [ "species_10039765" ], "modifiers": [ [ "species_10039759", "catalyst" ], [ "species_10039776", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "species_74016", "C4T8B4", "ENSBTAT00000018469", "species_1524071", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146" ] }, "reaction_10039782": { "compartment": "compartment_876", "id": "reaction_10039782", "reactome": "R-BTA-173631", "name": "Activation of C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039765" ], "products": [ "species_10039462" ], "modifiers": [ [ "species_10039765", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10054736": { "compartment": "compartment_876", "id": "reaction_10054736", "reactome": "R-BTA-981713", "name": "C4b binds to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039322", "species_983438" ], "products": [ "species_10054643" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10053134": { "compartment": "compartment_17906", "id": "reaction_10053134", "reactome": "R-BTA-936564", "name": "NLRX1 inhibits MAVS-DDX58 interaction.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10053130" ], "products": [ "species_10053132" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000016601", "F1MUU5", "ENSBTAT00000016601", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10053122": { "compartment": "compartment_70101", "id": "reaction_10053122", "reactome": "R-BTA-936563", "name": "ISGylation of DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10053118" ], "products": [ "species_10053120" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10053095": { "compartment": "compartment_7660", "id": "reaction_10053095", "reactome": "R-BTA-936380", "name": "Interaction of PIN1 with p-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053091", "species_10053086" ], "products": [ "species_10053093" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056088": { "compartment": "compartment_7660", "id": "reaction_10056088", "reactome": "R-BTA-1028820", "name": "Formation of VAF (virus-activated factor) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056080", "species_10053054" ], "products": [ "species_10056086" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053058": { "compartment": "compartment_7660", "id": "reaction_10053058", "reactome": "R-BTA-933536", "name": "p-IRF7 dimer interacts with coactivator CBP/p300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040193", "species_10053054" ], "products": [ "species_10053056" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10092318": { "compartment": "compartment_17906", "id": "reaction_10092318", "reactome": "R-BTA-9709842", "name": "MAVS binds TOMM70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10070254" ], "products": [ "species_10092316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000019001", "Q08E34", "ENSBTAT00000019001", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10056090": { "compartment": "compartment_70101", "id": "reaction_10056090", "reactome": "R-BTA-1028821", "name": "Dimerization of Phospho IRF3 or phospho IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039556", "species_10039554", "species_10056078" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10056082": { "compartment": "compartment_13231", "id": "reaction_10056082", "reactome": "R-BTA-1028816", "name": "Translocation of phosphorylated IRF3,IRF7 dimers into nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556", "species_10039554", "species_10056078" ], "products": [ "species_10056080", "species_10040193", "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056084": { "compartment": "compartment_7660", "id": "reaction_10056084", "reactome": "R-BTA-1028817", "name": "CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053054", "species_10040189" ], "products": [ "species_10056076" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10066559": { "compartment": "compartment_70101", "id": "reaction_10066559", "reactome": "R-BTA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066555", "species_3134861" ], "products": [ "species_10066557" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008082", "Q05B79", "ENSBTAT00000008082" ] }, "reaction_10090837": { "compartment": "compartment_13231", "id": "reaction_10090837", "reactome": "R-BTA-9604487", "name": "p-IRF7:p-IRF7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10066536": { "compartment": "compartment_70101", "id": "reaction_10066536", "reactome": "R-BTA-3134804", "name": "STING ubiquitination by TRIM32 or TRIM56", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10061500" ], "products": [ "species_10066530", "species_10055114" ], "modifiers": [ [ "species_10061500", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801", "ENSBTAT00000071484", "ENSBTAT00000022801", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10061502": { "compartment": "compartment_70101", "id": "reaction_10061502", "reactome": "R-BTA-1964496", "name": "STING binds TRIM32 or TRIM56 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055114", "species_10061498" ], "products": [ "species_10061500" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022801", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10066551": { "compartment": "compartment_70101", "id": "reaction_10066551", "reactome": "R-BTA-3134946", "name": "DDX41 ubiquitination by TRIM21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054900", "species_10033408", "species_10066540" ], "products": [ "species_10066548" ], "modifiers": [ [ "species_10054900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018459", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "Q7YRV4", "ENSBTAT00000018459", "ENSBTAT00000018459" ] }, "reaction_10066608": { "compartment": "compartment_70101", "id": "reaction_10066608", "reactome": "R-BTA-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10066604" ], "products": [ "species_10066606" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "E1BIN9", "ENSBTAT00000011748", "species_874088" ] }, "reaction_10065388": { "compartment": "compartment_70101", "id": "reaction_10065388", "reactome": "R-BTA-2395992", "name": "p-T,4S-IRF3 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039546" ], "products": [ "species_10039556" ], "modifiers": [], "additional_components": [ "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10063376": { "compartment": "compartment_70101", "id": "reaction_10063376", "reactome": "R-BTA-2032396", "name": "Dimerized phospho-IRF3 migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556" ], "products": [ "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10067225": { "compartment": "compartment_70101", "id": "reaction_10067225", "reactome": "R-BTA-3249372", "name": "p-S407,Y641-STAT6 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067208" ], "products": [ "species_10067210" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067229": { "compartment": "compartment_70101", "id": "reaction_10067229", "reactome": "R-BTA-3249378", "name": "STING recruits TBK1 and STAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_10046560", "species_10065393" ], "products": [ "species_10067227" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067231": { "compartment": "compartment_70101", "id": "reaction_10067231", "reactome": "R-BTA-3249379", "name": "p-S407-STAT6 is phosphorylated at Tyr641", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067220", "species_113592" ], "products": [ "species_29370", "species_10067208" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "ENSBTAT00000008311" ] }, "reaction_10067233": { "compartment": "compartment_70101", "id": "reaction_10067233", "reactome": "R-BTA-3249390", "name": "TBK1 is phosphorylated within STING:TBK1:STAT6 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10067227" ], "products": [ "species_10067218", "species_29370" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067216": { "compartment": "compartment_70101", "id": "reaction_10067216", "reactome": "R-BTA-3249370", "name": "p-S407,Y641-STAT6 dimer migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067210" ], "products": [ "species_10067214" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067223": { "compartment": "compartment_70101", "id": "reaction_10067223", "reactome": "R-BTA-3249371", "name": "TBK1 phosphorylates STAT6 at Ser407", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067218", "species_113592" ], "products": [ "species_10067220", "species_29370", "species_10065404" ], "modifiers": [ [ "species_10067218", "catalyst" ] ], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065402": { "compartment": "compartment_70101", "id": "reaction_10065402", "reactome": "R-BTA-2396002", "name": "TBK1 is phosphorylated within STING:TBK1:IRF3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065395", "species_113592" ], "products": [ "species_29370", "species_10065400" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065407": { "compartment": "compartment_70101", "id": "reaction_10065407", "reactome": "R-BTA-2396007", "name": "IRF3 is phosphorylated by TBK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065400" ], "products": [ "species_29370", "species_10065404", "species_10039546" ], "modifiers": [ [ "species_10065400", "catalyst" ] ], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10066880": { "compartment": "compartment_12045", "id": "reaction_10066880", "reactome": "R-BTA-3244643", "name": "STING binds cyclic GMP-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3244587", "species_10065409" ], "products": [ "species_10066878" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "species_3244587" ] }, "reaction_10090019": { "compartment": "compartment_70101", "id": "reaction_10090019", "reactome": "R-BTA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8982080", "species_10066540" ], "products": [ "species_10090017" ], "modifiers": [], "additional_components": [ "species_2395973", "CHEBI:47037", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "species_2395973", "CHEBI:47037" ] }, "reaction_10065413": { "compartment": "compartment_12045", "id": "reaction_10065413", "reactome": "R-BTA-2396009", "name": "STING binds c-di-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065409", "species_2395973" ], "products": [ "species_10065411" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "species_2395973", "Q2KI99", "ENSBTAT00000071484" ] }, "reaction_10066532": { "compartment": "compartment_12045", "id": "reaction_10066532", "reactome": "R-BTA-3134800", "name": "STING dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061498" ], "products": [ "species_10065409" ], "modifiers": [ [ "species_10066530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "ENSBTAT00000071484" ] }, "reaction_10081432": { "compartment": "compartment_984", "id": "reaction_10081432", "reactome": "R-BTA-6803063", "name": "RNASEs bind bacterial LPS, PGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_6803074" ], "products": [ "species_10081430" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "CHEBI:55478", "species_6789198", "species_166005", "CHEBI:55478", "species_6789198", "species_166005", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10082008": { "compartment": "compartment_984", "id": "reaction_10082008", "reactome": "R-BTA-6807565", "name": "GNLY is transferred to the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939" ], "products": [ "species_10082006" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "ENSBTAT00000083501" ] }, "reaction_10056539": { "compartment": "compartment_984", "id": "reaction_10056539", "reactome": "R-BTA-1222685", "name": "Cathelicidin LL-37 binds to bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056535", "species_8879165" ], "products": [ "species_10056537" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044788", "P33046", "ENSBTAT00000044788" ] }, "reaction_10082012": { "compartment": "compartment_1222282", "id": "reaction_10082012", "reactome": "R-BTA-6807578", "name": "GNLY binds the bacterial cell surface in the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082006", "species_8931784" ], "products": [ "species_10082010" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10083100": { "compartment": "compartment_984", "id": "reaction_10083100", "reactome": "R-BTA-6813626", "name": "LEAP2 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083096", "species_8931784" ], "products": [ "species_10083098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025186", "species_1462049", "species_1462049", "Q95JC3", "ENSBTAT00000025186" ] }, "reaction_10070906": { "compartment": "compartment_984", "id": "reaction_10070906", "reactome": "R-BTA-5229273", "name": "LCN2:2,5DHBA binds Fe3+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070902", "species_912516" ], "products": [ "species_10070904" ], "modifiers": [], "additional_components": [ "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806", "species_917966", "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806" ] }, "reaction_10056416": { "compartment": "compartment_1222282", "id": "reaction_10056416", "reactome": "R-BTA-1222491", "name": "Lactoferrin scavenges iron ions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2101051", "species_10056412", "species_1222611" ], "products": [ "species_10056414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001704", "species_917966", "P24627", "ENSBTAT00000001704", "species_2101051" ] }, "reaction_10078759": { "compartment": "compartment_984", "id": "reaction_10078759", "reactome": "R-BTA-6798489", "name": "S100A7 or S100A7A binds Zn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078755", "species_158417" ], "products": [ "species_10078757" ], "modifiers": [], "additional_components": [ "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "species_29426", "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838" ] }, "reaction_10082004": { "compartment": "compartment_984", "id": "reaction_10082004", "reactome": "R-BTA-6807144", "name": "HTN1,HTN3 or HTN5 binds the bacterial anionic surface ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081994", "species_8931784" ], "products": [ "species_10082002" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077381", "species_1462049", "species_1462049", "A0A3Q1LX31", "ENSBTAT00000077381" ] }, "reaction_10081559": { "compartment": "compartment_984", "id": "reaction_10081559", "reactome": "R-BTA-6804527", "name": "INTL1 binds bacterial glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081555", "species_6804535" ], "products": [ "species_10081557" ], "modifiers": [], "additional_components": [ "species_74016", "G3N3R4", "ENSBTAT00000064812", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "species_74016", "G3N3R4", "ENSBTAT00000064812" ] }, "reaction_10081943": { "compartment": "compartment_984", "id": "reaction_10081943", "reactome": "R-BTA-6806732", "name": "GNLY binds the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939", "species_8931784" ], "products": [ "species_10081941" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10082967": { "compartment": "compartment_5083403", "id": "reaction_10082967", "reactome": "R-BTA-6810643", "name": "EPPIN protein complex binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082963" ], "products": [ "species_10082965" ], "modifiers": [], "additional_components": [ "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324", "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324" ] }, "reaction_10084683": { "compartment": "compartment_984", "id": "reaction_10084683", "reactome": "R-BTA-8862300", "name": "LYZ binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10079373" ], "products": [ "species_10084681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038266", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10080842": { "compartment": "compartment_984", "id": "reaction_10080842", "reactome": "R-BTA-6799977", "name": "PGLYRP2 hydrolyzes bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080839", "species_109276" ], "products": [ "species_10080837", "species_6799970", "species_6799975" ], "modifiers": [ [ "species_10080837", "catalyst" ], [ "species_158417", "catalyst" ] ], "additional_components": [ "species_6789198", "E1BH94", "ENSBTAT00000047024", "E1BH94", "ENSBTAT00000047024", "CHEBI:28881", "species_1678743", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10080844": { "compartment": "compartment_984", "id": "reaction_10080844", "reactome": "R-BTA-6799981", "name": "PGLYRP2 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080837", "species_6789198" ], "products": [ "species_10080839" ], "modifiers": [], "additional_components": [ "E1BH94", "ENSBTAT00000047024", "species_6789198", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10084686": { "compartment": "compartment_984", "id": "reaction_10084686", "reactome": "R-BTA-8862320", "name": "LYZ hydrolyzes peptidoglycans in the bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10084681" ], "products": [ "species_6788991", "species_6788982" ], "modifiers": [ [ "species_10084681", "catalyst" ] ], "additional_components": [ "P80189", "ENSBTAT00000038266", "species_6789198", "species_1236715", "CHEBI:21615", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10058388": { "compartment": "compartment_17963", "id": "reaction_10058388", "reactome": "R-BTA-1462023", "name": "Pre-pro-defensins are cleaved to remove the signal peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058328" ], "products": [ "species_10058386" ], "modifiers": [], "additional_components": [ "A0A3Q1M0J5", "ENSBTAT00000086067", "O02775", "ENSBTAT00000009756", "A0A3Q1ME63", "ENSBTAT00000074783", "P25068", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "Q50JB9", "ENSBTAT00000072863", "G3MWU3", "ENSBTAT00000074783", "Q5W5I5", "ENSBTAT00000069740", "A0A452DIQ0", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "Q28880", "ENSBTAT00000050266", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10081410": { "compartment": "compartment_984", "id": "reaction_10081410", "reactome": "R-BTA-6801808", "name": "REG3A,REG3G binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10081389" ], "products": [ "species_10081408" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "P23132", "ENSBTAT00000086119", "species_6789198" ] }, "reaction_10082183": { "compartment": "compartment_984", "id": "reaction_10082183", "reactome": "R-BTA-6809521", "name": "BPIF binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082179" ], "products": [ "species_10082181" ], "modifiers": [], "additional_components": [ "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454", "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454" ] }, "reaction_10081404": { "compartment": "compartment_984", "id": "reaction_10081404", "reactome": "R-BTA-6801766", "name": "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081399" ], "products": [ "species_10081389", "species_10081401" ], "modifiers": [ [ "species_10058556", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000028731" ] }, "reaction_10080831": { "compartment": "compartment_984", "id": "reaction_10080831", "reactome": "R-BTA-6799959", "name": "PGLYRP3,4 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10080827" ], "products": [ "species_10080829" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "A0A3Q1M1U5", "ENSBTAT00000078335", "A0A3Q1M1U5", "ENSBTAT00000078335", "species_6789198" ] }, "reaction_10081406": { "compartment": "compartment_984", "id": "reaction_10081406", "reactome": "R-BTA-6801776", "name": "REG3A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081389", "species_8931784" ], "products": [ "species_10081391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "species_1462049", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10087601": { "compartment": "compartment_984", "id": "reaction_10087601", "reactome": "R-BTA-8948027", "name": "RNASEs bind bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_8931784" ], "products": [ "species_10087599" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "species_1462049", "species_1462049", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10081397": { "compartment": "compartment_984", "id": "reaction_10081397", "reactome": "R-BTA-6801762", "name": "REG3A oligomerize to form a pore complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081391" ], "products": [ "species_10081395" ], "modifiers": [ [ "species_166005", "inhibitor" ] ], "additional_components": [ "species_1462049", "P23132", "ENSBTAT00000086119", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10081385": { "compartment": "compartment_984", "id": "reaction_10081385", "reactome": "R-BTA-6801687", "name": "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081382" ], "products": [ "species_10056535" ], "modifiers": [ [ "species_10080371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044788", "ENSBTAT00000044788", "ENSBTAT00000064845" ] }, "reaction_10082977": { "compartment": "compartment_984", "id": "reaction_10082977", "reactome": "R-BTA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10082971" ], "products": [ "species_10082975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056512", "A1A4Q6", "ENSBTAT00000056512", "species_166005" ] }, "reaction_10083106": { "compartment": "compartment_984", "id": "reaction_10083106", "reactome": "R-BTA-6813659", "name": "ELANE, CTSG or PRTN3 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10083102" ], "products": [ "species_10083104" ], "modifiers": [], "additional_components": [ "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480", "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10084706": { "compartment": "compartment_984", "id": "reaction_10084706", "reactome": "R-BTA-8862771", "name": "PLA2G2A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059808", "species_8931784" ], "products": [ "species_10084704" ], "modifiers": [], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "species_1462049", "species_1462049", "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10051836": { "compartment": "compartment_70101", "id": "reaction_10051836", "reactome": "R-BTA-879221", "name": "PSTPIP1 binds Pyrin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051824", "species_10051832" ], "products": [ "species_10051834" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q8", "ENSBTAT00000085633", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1M2Q8", "ENSBTAT00000085633" ] }, "reaction_10077919": { "compartment": "compartment_21994", "id": "reaction_10077919", "reactome": "R-BTA-6789031", "name": "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077916", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10084322": { "compartment": "compartment_984", "id": "reaction_10084322", "reactome": "R-BTA-8855490", "name": "Lactoperoxidase (LPO) produces OSCN-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_8855492" ], "products": [ "species_109276", "species_8855489" ], "modifiers": [ [ "species_10084319", "catalyst" ] ], "additional_components": [ "P80025", "ENSBTAT00000016986", "CHEBI:55376" ] }, "reaction_10086405": { "compartment": "compartment_1222282", "id": "reaction_10086405", "reactome": "R-BTA-8933635", "name": "Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_1470067", "species_6789221" ], "products": [ "species_8933637", "species_1222475" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077924": { "compartment": "compartment_1222282", "id": "reaction_10077924", "reactome": "R-BTA-6789126", "name": "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077926": { "compartment": "compartment_21994", "id": "reaction_10077926", "reactome": "R-BTA-6789136", "name": "Myeloperoxidase (MPO) binds to the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077914", "species_983438" ], "products": [ "species_10077916" ], "modifiers": [], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376", "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077921": { "compartment": "compartment_1222282", "id": "reaction_10077921", "reactome": "R-BTA-6789092", "name": "NOX2 generates superoxide anion from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_1222561" ], "products": [ "species_1222461", "species_70106", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10077904": { "compartment": "compartment_70101", "id": "reaction_10077904", "reactome": "R-BTA-6788999", "name": "HV1-mediated H+ transfer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10077901", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10047907": { "compartment": "compartment_70101", "id": "reaction_10047907", "reactome": "R-BTA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10047904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069366" ] }, "reaction_10056531": { "compartment": "compartment_1222693", "id": "reaction_10056531", "reactome": "R-BTA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10056528", "catalyst" ] ], "additional_components": [ "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "O97681", "ENSBTAT00000009563", "E1BGJ7", "ENSBTAT00000005588", "Q1RMS1", "ENSBTAT00000000367", "A0A3Q1MS24", "ENSBTAT00000075240" ] }, "reaction_10063368": { "compartment": "compartment_876", "id": "reaction_10063368", "reactome": "R-BTA-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10063365", "catalyst" ] ], "additional_components": [ "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10049304": { "compartment": "compartment_70101", "id": "reaction_10049304", "reactome": "R-BTA-432909", "name": "Interaction of Plectin with Integrin beta 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043", "species_10044490" ], "products": [ "species_10049302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082561", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRS3", "ENSBTAT00000082561" ] }, "reaction_10075165": { "compartment": "compartment_7660", "id": "reaction_10075165", "reactome": "R-BTA-5686475", "name": "SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075149", "species_10075161" ], "products": [ "species_10075163" ], "modifiers": [], "additional_components": [ "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10075151": { "compartment": "compartment_7660", "id": "reaction_10075151", "reactome": "R-BTA-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075143", "species_10075139" ], "products": [ "species_10075149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053203", "G3N153", "ENSBTAT00000065898", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10050458": { "compartment": "compartment_70101", "id": "reaction_10050458", "reactome": "R-BTA-451056", "name": "Microtubule-independent trafficking of connexons to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050452" ], "products": [ "species_10050456" ], "modifiers": [], "additional_components": [ "A2VE67", "ENSBTAT00000023167", "A2VE67", "ENSBTAT00000023167" ] }, "reaction_10040857": { "compartment": "compartment_70101", "id": "reaction_10040857", "reactome": "R-BTA-190782", "name": "Budding of connexon-containing transport vesicles from the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040855" ], "products": [ "species_10040800" ], "modifiers": [], "additional_components": [ "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398" ] }, "reaction_10040842": { "compartment": "compartment_70101", "id": "reaction_10040842", "reactome": "R-BTA-190520", "name": "Association of Golgi transport vesicles with microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10040800" ], "products": [ "species_10040840" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398", "species_29438", "species_29420" ] }, "reaction_10036729": { "compartment": "compartment_7660", "id": "reaction_10036729", "reactome": "R-BTA-110231", "name": "Cleavage of uracil by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036724" ], "products": [ "species_10036726", "species_29554" ], "modifiers": [ [ "species_10036724", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036716": { "compartment": "compartment_7660", "id": "reaction_10036716", "reactome": "R-BTA-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036713" ], "products": [ "species_29692", "species_10036706" ], "modifiers": [ [ "species_10036713", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036767": { "compartment": "compartment_7660", "id": "reaction_10036767", "reactome": "R-BTA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036764" ], "products": [ "species_10036757", "species_5636006" ], "modifiers": [ [ "species_10036764", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10036736": { "compartment": "compartment_7660", "id": "reaction_10036736", "reactome": "R-BTA-110232", "name": "Cleavage of thymine by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036733" ], "products": [ "species_10036726", "species_29692" ], "modifiers": [ [ "species_10036733", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036709": { "compartment": "compartment_7660", "id": "reaction_10036709", "reactome": "R-BTA-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036702" ], "products": [ "species_10036706", "species_29554" ], "modifiers": [ [ "species_10036702", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036743": { "compartment": "compartment_7660", "id": "reaction_10036743", "reactome": "R-BTA-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036740" ], "products": [ "species_10036706", "species_110233" ], "modifiers": [ [ "species_10036740", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10089640": { "compartment": "compartment_7660", "id": "reaction_10089640", "reactome": "R-BTA-9008822", "name": "PPM1D dephosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10089633" ], "products": [ "species_10086640", "species_113541" ], "modifiers": [ [ "species_10089637", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000012404" ] }, "reaction_10086716": { "compartment": "compartment_7660", "id": "reaction_10086716", "reactome": "R-BTA-8939688", "name": "SCF(SKP2) complex binds RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10086712" ], "products": [ "species_10086714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089679": { "compartment": "compartment_70101", "id": "reaction_10089679", "reactome": "R-BTA-9009308", "name": "STUB1 polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10089672" ], "products": [ "species_10055082", "species_10089674" ], "modifiers": [ [ "species_10089672", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000025473", "ENSBTAT00000066565", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089681": { "compartment": "compartment_70101", "id": "reaction_10089681", "reactome": "R-BTA-9009309", "name": "RUNX2 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089668", "species_10055082" ], "products": [ "species_10089672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000025473", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10086724": { "compartment": "compartment_7660", "id": "reaction_10086724", "reactome": "R-BTA-8939706", "name": "SCF(SKP2) polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10086714" ], "products": [ "species_10086719", "species_10086712" ], "modifiers": [ [ "species_10086714", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089610": { "compartment": "compartment_7660", "id": "reaction_10089610", "reactome": "R-BTA-9008412", "name": "CDK4 phosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10086640" ], "products": [ "species_113582", "species_10089605" ], "modifiers": [ [ "species_10089607", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10089357": { "compartment": "compartment_7660", "id": "reaction_10089357", "reactome": "R-BTA-8985343", "name": "RUNX2 binds SOX9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10089353" ], "products": [ "species_10089355" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000084141", "A0A3Q1MN22", "ENSBTAT00000084141", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10074877": { "compartment": "compartment_7660", "id": "reaction_10074877", "reactome": "R-BTA-5685319", "name": "CX3 complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10074873" ], "products": [ "species_10074875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000013145", "A0A452DJ33", "ENSBTAT00000013145", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10065177": { "compartment": "compartment_7660", "id": "reaction_10065177", "reactome": "R-BTA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064869", "species_10064891" ], "products": [ "species_10065175" ], "modifiers": [], "additional_components": [ "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064904": { "compartment": "compartment_7660", "id": "reaction_10064904", "reactome": "R-BTA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064897", "species_113671", "species_113685" ], "products": [ "species_10064901", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10064897", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067", "species_71067", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067" ] }, "reaction_10065563": { "compartment": "compartment_7660", "id": "reaction_10065563", "reactome": "R-BTA-2429719", "name": "MCPH1 sequesters condensin II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065559", "species_10064869", "species_10050283" ], "products": [ "species_10065561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068774", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1M8A5", "ENSBTAT00000068774" ] }, "reaction_10065201": { "compartment": "compartment_7660", "id": "reaction_10065201", "reactome": "R-BTA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065186" ], "products": [ "species_113582", "species_10065198" ], "modifiers": [ [ "species_10065186", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "F1MPS0", "ENSBTAT00000039478", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064733": { "compartment": "compartment_7660", "id": "reaction_10064733", "reactome": "R-BTA-2168079", "name": "MASTL (GWL) phosphorylates ARPP19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10064715" ], "products": [ "species_113582", "species_10064723" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "A0A3Q1NDP8", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1NDP8", "ENSBTAT00000075206", "ENSBTAT00000022950" ] }, "reaction_10065572": { "compartment": "compartment_7660", "id": "reaction_10065572", "reactome": "R-BTA-2430535", "name": "MASTL phosphorylates ENSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065567" ], "products": [ "species_113582", "species_10065570" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009379", "ENSBTAT00000009379", "ENSBTAT00000022950" ] }, "reaction_10066345": { "compartment": "compartment_70101", "id": "reaction_10066345", "reactome": "R-BTA-2984258", "name": "NEK9 phosphorylates NEK6/NEK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066322", "species_113592" ], "products": [ "species_10066342", "species_29370" ], "modifiers": [ [ "species_10066322", "catalyst" ] ], "additional_components": [ "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10066324": { "compartment": "compartment_70101", "id": "reaction_10066324", "reactome": "R-BTA-2980720", "name": "NEK9 binds NEK6/NEK7 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066309", "species_10066320" ], "products": [ "species_10066322" ], "modifiers": [], "additional_components": [ "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10070705": { "compartment": "compartment_13231", "id": "reaction_10070705", "reactome": "R-BTA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10069478", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005" ] }, "reaction_10069491": { "compartment": "compartment_13231", "id": "reaction_10069491", "reactome": "R-BTA-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10069470" ], "products": [ "species_113550", "species_10069478" ], "modifiers": [ [ "species_10069488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LKP8", "ENSBTAT00000083005", "Q1RMV9", "ENSBTAT00000025896", "Q3ZBP2", "ENSBTAT00000046962" ] }, "reaction_10065095": { "compartment": "compartment_20699", "id": "reaction_10065095", "reactome": "R-BTA-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065087" ], "products": [ "species_10065092", "species_29370" ], "modifiers": [ [ "species_10065087", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10038371": { "compartment": "compartment_5460", "id": "reaction_10038371", "reactome": "R-BTA-159566", "name": "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159447" ], "products": [ "species_29374", "species_159564" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10038354": { "compartment": "compartment_5460", "id": "reaction_10038354", "reactome": "R-BTA-159443", "name": "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159446" ], "products": [ "species_159448", "species_159450", "species_159447" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10039520": { "compartment": "compartment_17906", "id": "reaction_10039520", "reactome": "R-BTA-168848", "name": "tBID binds to inactive BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037233" ], "products": [ "species_10037620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10037237": { "compartment": "compartment_17906", "id": "reaction_10037237", "reactome": "R-BTA-114263", "name": "Oligomerization of BAK at the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037233" ], "products": [ "species_10037235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10037622": { "compartment": "compartment_17906", "id": "reaction_10037622", "reactome": "R-BTA-139895", "name": "tBID activates BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037620" ], "products": [ "species_10037269", "species_10037233" ], "modifiers": [], "additional_components": [ "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000000549" ] }, "reaction_10047809": { "compartment": "compartment_876", "id": "reaction_10047809", "reactome": "R-BTA-400434", "name": "GPR40 (Free fatty acid receptor 1, FFAR1) binds fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10058908": { "compartment": "compartment_12045", "id": "reaction_10058908", "reactome": "R-BTA-1482679", "name": "PA is hydrolysed to 1-acyl LPA by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10077777": { "compartment": "compartment_70101", "id": "reaction_10077777", "reactome": "R-BTA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10077774", "catalyst" ] ], "additional_components": [ "A0A3Q1MMR4", "ENSBTAT00000085985", "F1MSS2", "ENSBTAT00000017473" ] }, "reaction_10058896": { "compartment": "compartment_70101", "id": "reaction_10058896", "reactome": "R-BTA-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10058834": { "compartment": "compartment_17906", "id": "reaction_10058834", "reactome": "R-BTA-1482548", "name": "1-acyl LPA is acylated to PA by AGPAT5 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500580" ], "products": [ "species_1500590", "species_76194" ], "modifiers": [ [ "species_10058831", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006476" ] }, "reaction_10059860": { "compartment": "compartment_984", "id": "reaction_10059860", "reactome": "R-BTA-1602446", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10088649": { "compartment": "compartment_17906", "id": "reaction_10088649", "reactome": "R-BTA-8954398", "name": "PLD6 dimer hydrolyses cardiolipin to PA and PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189422", "species_8954419" ], "products": [ "species_8954401", "species_1500590" ], "modifiers": [ [ "species_10088630", "catalyst" ], [ "species_10088647", "catalyst" ] ], "additional_components": [ "E1BE10", "ENSBTAT00000010531", "F1MNB3", "ENSBTAT00000043938", "Q1JPG0", "ENSBTAT00000014090" ] }, "reaction_10086248": { "compartment": "compartment_984", "id": "reaction_10086248", "reactome": "R-BTA-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8878780" ], "products": [ "species_8878776", "species_109277" ], "modifiers": [ [ "species_10086245", "catalyst" ] ], "additional_components": [ "species_29426", "species_74016", "F1N2M5", "ENSBTAT00000043359" ] }, "reaction_10058923": { "compartment": "compartment_17906", "id": "reaction_10058923", "reactome": "R-BTA-1482695", "name": "G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_76194", "species_1500580" ], "modifiers": [ [ "species_10058920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015359" ] }, "reaction_10035786": { "compartment": "compartment_12045", "id": "reaction_10035786", "reactome": "R-BTA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10035783", "catalyst" ] ], "additional_components": [ "Q95JH2", "ENSBTAT00000083979", "A6H7D4", "ENSBTAT00000007532", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1LJ33", "ENSBTAT00000076188", "G5E5P6", "ENSBTAT00000087371", "E1BGF8", "ENSBTAT00000023396", "A0A3S5ZPU2", "ENSBTAT00000006476", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10058858": { "compartment": "compartment_17906", "id": "reaction_10058858", "reactome": "R-BTA-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500590" ], "products": [ "species_1500580", "species_1524103" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059114": { "compartment": "compartment_12045", "id": "reaction_10059114", "reactome": "R-BTA-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10059111", "catalyst" ] ], "additional_components": [ "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10051264": { "compartment": "compartment_12045", "id": "reaction_10051264", "reactome": "R-BTA-549112", "name": "G3P is acylated to 1-acyl LPA by AGPAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_1500604", "species_76194" ], "modifiers": [ [ "species_10035769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007532" ] }, "reaction_10035812": { "compartment": "compartment_70101", "id": "reaction_10035812", "reactome": "R-BTA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10035809", "catalyst" ] ], "additional_components": [ "A0A452DJJ3", "ENSBTAT00000021683", "A0A3Q1MUU4", "ENSBTAT00000057343" ] }, "reaction_10044235": { "compartment": "compartment_17960", "id": "reaction_10044235", "reactome": "R-BTA-211959", "name": "CYP3A43 6b-hydroxylates TEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044177", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044255": { "compartment": "compartment_17960", "id": "reaction_10044255", "reactome": "R-BTA-211968", "name": "CYP2W1 oxidises INDOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_216547" ], "products": [ "species_113519", "species_113564", "species_216598" ], "modifiers": [ [ "species_10044252", "catalyst" ] ], "additional_components": [ "F1MXW1", "ENSBTAT00000023544" ] }, "reaction_10044158": { "compartment": "compartment_17960", "id": "reaction_10044158", "reactome": "R-BTA-211874", "name": "CYP2S1 4-hydroxylates atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044155", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024282" ] }, "reaction_10044242": { "compartment": "compartment_17960", "id": "reaction_10044242", "reactome": "R-BTA-211960", "name": "CYP2U1 19-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_216620", "species_113519", "species_113564" ], "modifiers": [ [ "species_10044239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017246" ] }, "reaction_10044247": { "compartment": "compartment_17960", "id": "reaction_10044247", "reactome": "R-BTA-211962", "name": "CYP4F11 16-hydroxylates 3OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_216621", "species_113601" ], "products": [ "species_113519", "species_113564", "species_216612" ], "modifiers": [ [ "species_10044244", "catalyst" ] ], "additional_components": [ "A0A3Q1MCJ2", "ENSBTAT00000073532" ] }, "reaction_10078408": { "compartment": "compartment_70101", "id": "reaction_10078408", "reactome": "R-BTA-6793685", "name": "Ubiquitinated TP53 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675" ], "products": [ "species_10078406" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10033535": { "compartment": "compartment_7660", "id": "reaction_10033535", "reactome": "R-BTA-69685", "name": "CHEK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10033532", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000006518" ] }, "reaction_10076341": { "compartment": "compartment_7660", "id": "reaction_10076341", "reactome": "R-BTA-5693609", "name": "ATM phosphorylates TP53 at S15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000040104" ] }, "reaction_10081470": { "compartment": "compartment_7660", "id": "reaction_10081470", "reactome": "R-BTA-6803719", "name": "TP53 binds ZNF385A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081466" ], "products": [ "species_10081468" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070196", "A0A3Q1M6W9", "ENSBTAT00000070196", "P67939", "ENSBTAT00000001420" ] }, "reaction_10057800": { "compartment": "compartment_7660", "id": "reaction_10057800", "reactome": "R-BTA-1363303", "name": "p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056559" ], "products": [ "species_10057798" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057804": { "compartment": "compartment_7660", "id": "reaction_10057804", "reactome": "R-BTA-1363306", "name": "p130 (RBL2) binds Cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056543" ], "products": [ "species_10057802" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057808": { "compartment": "compartment_7660", "id": "reaction_10057808", "reactome": "R-BTA-1363311", "name": "p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056608" ], "products": [ "species_10057806" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057812": { "compartment": "compartment_7660", "id": "reaction_10057812", "reactome": "R-BTA-1363314", "name": "p107 (RBL1) binds CyclinE/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056606" ], "products": [ "species_10057810" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000015333", "E1BMR3", "ENSBTAT00000015333", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10037433": { "compartment": "compartment_70101", "id": "reaction_10037433", "reactome": "R-BTA-114558", "name": "Thrombin-activated PARs activate Gq", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037427" ], "products": [ "species_10037431", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10037353": { "compartment": "compartment_70101", "id": "reaction_10037353", "reactome": "R-BTA-114552", "name": "Thrombin-activated PARs activate G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037346" ], "products": [ "species_10037350", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10047880": { "compartment": "compartment_70101", "id": "reaction_10047880", "reactome": "R-BTA-418172", "name": "F2R binds ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10047872" ], "products": [ "species_10047878" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "ENSBTAT00000026902", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092299": { "compartment": "compartment_984", "id": "reaction_10092299", "reactome": "R-BTA-9708859", "name": "Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092295" ], "products": [ "species_10047872", "species_10092297" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026902", "ENSBTAT00000026902", "ENSBTAT00000026902", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10037580": { "compartment": "compartment_984", "id": "reaction_10037580", "reactome": "R-BTA-114697", "name": "Activated thrombin (factor IIa) cleaves PAR3,4, activating them", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037563" ], "products": [ "species_10037569", "species_10037342" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10047886": { "compartment": "compartment_70101", "id": "reaction_10047886", "reactome": "R-BTA-418200", "name": "SRC-1 bound to ARRB2 is not activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047884" ], "products": [ "species_10047884" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078", "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10041337": { "compartment": "compartment_5460", "id": "reaction_10041337", "reactome": "R-BTA-193713", "name": "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193785", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193747", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041339": { "compartment": "compartment_5460", "id": "reaction_10041339", "reactome": "R-BTA-193719", "name": "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193708", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193716", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041341": { "compartment": "compartment_70101", "id": "reaction_10041341", "reactome": "R-BTA-193727", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041343": { "compartment": "compartment_17951", "id": "reaction_10041343", "reactome": "R-BTA-193736", "name": "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041361": { "compartment": "compartment_70101", "id": "reaction_10041361", "reactome": "R-BTA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041363": { "compartment": "compartment_5460", "id": "reaction_10041363", "reactome": "R-BTA-193787", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193777", "species_113600" ], "products": [ "species_113563", "species_193782", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041365": { "compartment": "compartment_70101", "id": "reaction_10041365", "reactome": "R-BTA-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_193724", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041367": { "compartment": "compartment_5460", "id": "reaction_10041367", "reactome": "R-BTA-193792", "name": "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193720", "species_113529", "species_113600" ], "products": [ "species_193708", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041335": { "compartment": "compartment_70101", "id": "reaction_10041335", "reactome": "R-BTA-193711", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041193": { "compartment": "compartment_70101", "id": "reaction_10041193", "reactome": "R-BTA-192061", "name": "CYP46A1 24-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_192060", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041190", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068208" ] }, "reaction_10041353": { "compartment": "compartment_70101", "id": "reaction_10041353", "reactome": "R-BTA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041355": { "compartment": "compartment_17951", "id": "reaction_10041355", "reactome": "R-BTA-193763", "name": "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193793" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041357": { "compartment": "compartment_70101", "id": "reaction_10041357", "reactome": "R-BTA-193766", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041359": { "compartment": "compartment_5460", "id": "reaction_10041359", "reactome": "R-BTA-193780", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193782", "species_113600" ], "products": [ "species_193785", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041217": { "compartment": "compartment_70101", "id": "reaction_10041217", "reactome": "R-BTA-192178", "name": "CYP39A1 7-hydroxylates 24OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192060", "species_70106", "species_29368", "species_29364" ], "products": [ "species_192189", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041214", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004736" ] }, "reaction_10041345": { "compartment": "compartment_5460", "id": "reaction_10041345", "reactome": "R-BTA-193737", "name": "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193716", "species_113600" ], "products": [ "species_193757", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041347": { "compartment": "compartment_70101", "id": "reaction_10041347", "reactome": "R-BTA-193743", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041349": { "compartment": "compartment_70101", "id": "reaction_10041349", "reactome": "R-BTA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041351": { "compartment": "compartment_70101", "id": "reaction_10041351", "reactome": "R-BTA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10047659": { "compartment": "compartment_70101", "id": "reaction_10047659", "reactome": "R-BTA-399939", "name": "Autophosphorylation of PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047616" ], "products": [ "species_29370", "species_10047656" ], "modifiers": [ [ "species_10047616", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047763": { "compartment": "compartment_70101", "id": "reaction_10047763", "reactome": "R-BTA-399952", "name": "Phosphorylation of LIMK-1 by PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047656", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10047618": { "compartment": "compartment_70101", "id": "reaction_10047618", "reactome": "R-BTA-399930", "name": "Activation of PAK by Rac1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047612", "species_10047592" ], "products": [ "species_10047616", "species_10047614" ], "modifiers": [], "additional_components": [ "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047753": { "compartment": "compartment_70101", "id": "reaction_10047753", "reactome": "R-BTA-399951", "name": "Phosphorylation of CRMPs by GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047714", "species_113592" ], "products": [ "species_10047750", "species_29370" ], "modifiers": [ [ "species_10041574", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "ENSBTAT00000056446" ] }, "reaction_10047717": { "compartment": "compartment_70101", "id": "reaction_10047717", "reactome": "R-BTA-399944", "name": "Phosphorylation of CRMPs by Cdk5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047695", "species_10047675" ], "products": [ "species_10047714", "species_29370" ], "modifiers": [ [ "species_10047695", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859" ] }, "reaction_10047735": { "compartment": "compartment_70101", "id": "reaction_10047735", "reactome": "R-BTA-399947", "name": "Tyrosine phosphorylation of CRMPs by Fes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047586", "species_113592", "species_10047675" ], "products": [ "species_10047732", "species_29370" ], "modifiers": [ [ "species_10043848", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "ENSBTAT00000003828" ] }, "reaction_10045244": { "compartment": "compartment_876", "id": "reaction_10045244", "reactome": "R-BTA-373748", "name": "SEMA4D interacts with CD72", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045240" ], "products": [ "species_10045242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000015162", "E1BPB4", "ENSBTAT00000015162", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10045236": { "compartment": "compartment_876", "id": "reaction_10045236", "reactome": "R-BTA-373746", "name": "SEMA4D interacts with CD45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045228" ], "products": [ "species_10045234" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000013320", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10089713": { "compartment": "compartment_984", "id": "reaction_10089713", "reactome": "R-BTA-9010815", "name": "SLITs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089709", "species_2299699" ], "products": [ "species_10089711" ], "modifiers": [], "additional_components": [ "F1MLJ7", "ENSBTAT00000061059", "species_2299699", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10090179": { "compartment": "compartment_984", "id": "reaction_10090179", "reactome": "R-BTA-9014812", "name": "ROBOs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043663", "species_2299699" ], "products": [ "species_10090177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061264", "species_2299699", "F1N739", "ENSBTAT00000061264" ] }, "reaction_10045517": { "compartment": "compartment_70101", "id": "reaction_10045517", "reactome": "R-BTA-376141", "name": "Interaction of ABL with ROBO1:SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10045513" ], "products": [ "species_10045515" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "ENSBTAT00000080797", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10049024": { "compartment": "compartment_70101", "id": "reaction_10049024", "reactome": "R-BTA-428888", "name": "Phosphorylation of ROBO1 by ABL kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10045515" ], "products": [ "species_29370", "species_10049021" ], "modifiers": [ [ "species_10045515", "catalyst" ] ], "additional_components": [ "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10089397": { "compartment": "compartment_876", "id": "reaction_10089397", "reactome": "R-BTA-8986258", "name": "SLIT2:ROBO1 binds CXCR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10089393" ], "products": [ "species_10089395" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048935": { "compartment": "compartment_876", "id": "reaction_10048935", "reactome": "R-BTA-428518", "name": "Glypican-1 (GPC1) binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048931", "species_10043667" ], "products": [ "species_10048933" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "ENSBTAT00000061059", "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10043671": { "compartment": "compartment_876", "id": "reaction_10043671", "reactome": "R-BTA-204364", "name": "ROBO1 binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043667", "species_10043663" ], "products": [ "species_10043669" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061059", "ENSBTAT00000061264", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048951": { "compartment": "compartment_70101", "id": "reaction_10048951", "reactome": "R-BTA-428534", "name": "Recruitment of Profilin by Ena/VASP proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048947", "species_10043457" ], "products": [ "species_10048949" ], "modifiers": [], "additional_components": [ "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10047449": { "compartment": "compartment_70101", "id": "reaction_10047449", "reactome": "R-BTA-392051", "name": "Recruitment of Grb2 to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047443", "species_10035485" ], "products": [ "species_10047447" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000006216", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10047455": { "compartment": "compartment_70101", "id": "reaction_10047455", "reactome": "R-BTA-392053", "name": "SOS binds Grb2 bound to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047447", "species_10035489" ], "products": [ "species_10047453" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000015471", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10047458": { "compartment": "compartment_70101", "id": "reaction_10047458", "reactome": "R-BTA-392054", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10047453", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10045509": { "compartment": "compartment_876", "id": "reaction_10045509", "reactome": "R-BTA-376122", "name": "DSCAM/DSCAML1 homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045505" ], "products": [ "species_10045507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082055", "A0A3Q1MBH9", "ENSBTAT00000082055" ] }, "reaction_10045224": { "compartment": "compartment_70101", "id": "reaction_10045224", "reactome": "R-BTA-373738", "name": "Neurofascin interacts with syntenin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10045216" ], "products": [ "species_10045222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "ENSBTAT00000069125", "A0A3Q1LMZ3", "ENSBTAT00000069125", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069192": { "compartment": "compartment_70101", "id": "reaction_10069192", "reactome": "R-BTA-3928615", "name": "EFNBs bind SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069057", "species_10069161" ], "products": [ "species_10069190" ], "modifiers": [], "additional_components": [ "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069226": { "compartment": "compartment_70101", "id": "reaction_10069226", "reactome": "R-BTA-3928640", "name": "PAKs phosphorylate MLC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049739" ], "products": [ "species_10049762", "species_29370" ], "modifiers": [ [ "species_10069218", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021328", "ENSBTAT00000021328", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438" ] }, "reaction_10069418": { "compartment": "compartment_70101", "id": "reaction_10069418", "reactome": "R-BTA-4093329", "name": "EFNBs bind SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10069057" ], "products": [ "species_10069416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069221": { "compartment": "compartment_70101", "id": "reaction_10069221", "reactome": "R-BTA-3928625", "name": "PAKs autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069208" ], "products": [ "species_10069218", "species_29370" ], "modifiers": [ [ "species_10069208", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10069188": { "compartment": "compartment_70101", "id": "reaction_10069188", "reactome": "R-BTA-3928614", "name": "EFNB:GRB4 binds GIT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069184", "species_10069179" ], "products": [ "species_10069186" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073530", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530" ] }, "reaction_10069223": { "compartment": "compartment_70101", "id": "reaction_10069223", "reactome": "R-BTA-3928639", "name": "p-EFNB binds GRB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045210", "species_10069177" ], "products": [ "species_10069179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542" ] }, "reaction_10069243": { "compartment": "compartment_876", "id": "reaction_10069243", "reactome": "R-BTA-3928646", "name": "EPHAs bind EFNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068993", "species_10069023" ], "products": [ "species_10069025" ], "modifiers": [], "additional_components": [ "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958" ] }, "reaction_10069131": { "compartment": "compartment_876", "id": "reaction_10069131", "reactome": "R-BTA-3928591", "name": "EPH:EFN tetramers oligomerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069127", "species_10069129" ], "products": [ "species_10069061" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069285": { "compartment": "compartment_876", "id": "reaction_10069285", "reactome": "R-BTA-3928656", "name": "gamma-secretase cleaves EPHB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069263" ], "products": [ "species_10069283", "species_10069273" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10069157": { "compartment": "compartment_876", "id": "reaction_10069157", "reactome": "R-BTA-3928604", "name": "SFKs phosphorylate VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069152" ], "products": [ "species_10069154", "species_29370" ], "modifiers": [ [ "species_10069152", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069159": { "compartment": "compartment_876", "id": "reaction_10069159", "reactome": "R-BTA-3928607", "name": "p-EPHs bind VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069150", "species_10048073" ], "products": [ "species_10069152" ], "modifiers": [], "additional_components": [ "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "ENSBTAT00000086853", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069194": { "compartment": "compartment_876", "id": "reaction_10069194", "reactome": "R-BTA-3928624", "name": "EPHBs bind EFNBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069055", "species_10069037" ], "products": [ "species_10069057" ], "modifiers": [], "additional_components": [ "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069146": { "compartment": "compartment_876", "id": "reaction_10069146", "reactome": "R-BTA-3928597", "name": "EPH:EFN dimers tetramerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069129" ], "products": [ "species_10069127" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069121": { "compartment": "compartment_70101", "id": "reaction_10069121", "reactome": "R-BTA-3928578", "name": "EPH receptors autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069061", "species_113592" ], "products": [ "species_29370", "species_10069118" ], "modifiers": [ [ "species_10069061", "catalyst" ] ], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069144": { "compartment": "compartment_70101", "id": "reaction_10069144", "reactome": "R-BTA-3928592", "name": "p190RhoGEF exchanges GTP for GDP on RHOA, activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069141", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10069435": { "compartment": "compartment_876", "id": "reaction_10069435", "reactome": "R-BTA-4093339", "name": "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069428", "species_29356" ], "products": [ "species_29372", "species_10069432" ], "modifiers": [ [ "species_10069428", "catalyst" ] ], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29420", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10069148": { "compartment": "compartment_70101", "id": "reaction_10069148", "reactome": "R-BTA-3928598", "name": "Recruitment of p190RhoGEF to p-FAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069139", "species_10069135" ], "products": [ "species_10069141" ], "modifiers": [], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000074225", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10091007": { "compartment": "compartment_12045", "id": "reaction_10091007", "reactome": "R-BTA-9614271", "name": "Autocleavage of ADGRG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090998" ], "products": [ "species_10091004" ], "modifiers": [ [ "species_10090998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895", "ENSBTAT00000079895" ] }, "reaction_10091009": { "compartment": "compartment_876", "id": "reaction_10091009", "reactome": "R-BTA-9614273", "name": "ADGRG heterodimer translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091004" ], "products": [ "species_10091004" ], "modifiers": [], "additional_components": [ "A0A3Q1MTZ4", "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895" ] }, "reaction_10074603": { "compartment": "compartment_876", "id": "reaction_10074603", "reactome": "R-BTA-5682709", "name": "LGI4 binds ADAM22,23,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074599", "species_10074595" ], "products": [ "species_10074601" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025189", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A6QLD0", "ENSBTAT00000025189" ] }, "reaction_10074641": { "compartment": "compartment_984", "id": "reaction_10074641", "reactome": "R-BTA-5682802", "name": "LGI3 binds ADAM22,23,synatxin1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074637" ], "products": [ "species_10074639" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000006011", "E1BFY8", "ENSBTAT00000006011", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10074613": { "compartment": "compartment_984", "id": "reaction_10074613", "reactome": "R-BTA-5682769", "name": "LGI2 binds ADAM22,23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074607" ], "products": [ "species_10074611" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000023124", "F1MZT1", "ENSBTAT00000023124", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10081915": { "compartment": "compartment_70101", "id": "reaction_10081915", "reactome": "R-BTA-6806610", "name": "Keratin filament formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081911" ], "products": [ "species_10081913" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081917": { "compartment": "compartment_70101", "id": "reaction_10081917", "reactome": "R-BTA-6806613", "name": "Keratin tetramers bind to form unit length filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081859" ], "products": [ "species_10081909" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081857": { "compartment": "compartment_70101", "id": "reaction_10081857", "reactome": "R-BTA-6805546", "name": "Keratin type I binds keratin type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081853", "species_10081739" ], "products": [ "species_10081855" ], "modifiers": [], "additional_components": [ "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081921": { "compartment": "compartment_70101", "id": "reaction_10081921", "reactome": "R-BTA-6806629", "name": "Formation of tonofilament bundles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081913" ], "products": [ "species_10081919" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081861": { "compartment": "compartment_70101", "id": "reaction_10081861", "reactome": "R-BTA-6805573", "name": "Keratin type I/type II heterodimers form tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081855" ], "products": [ "species_10081859" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10082871": { "compartment": "compartment_70101", "id": "reaction_10082871", "reactome": "R-BTA-6809663", "name": "Formation of hair keratin fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082865", "species_10081919" ], "products": [ "species_10082869" ], "modifiers": [], "additional_components": [ "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298" ] }, "reaction_10050085": { "compartment": "compartment_7660", "id": "reaction_10050085", "reactome": "R-BTA-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050064", "species_10050074" ], "products": [ "species_113582", "species_10050082" ], "modifiers": [ [ "species_10050074", "catalyst" ] ], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050116": { "compartment": "compartment_7660", "id": "reaction_10050116", "reactome": "R-BTA-448963", "name": "Interaction of MyoD:E protein with MEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050080", "species_10050112" ], "products": [ "species_10050114" ], "modifiers": [], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "A0A3Q1NNL3", "ENSBTAT00000079928" ] }, "reaction_10044090": { "compartment": "compartment_7660", "id": "reaction_10044090", "reactome": "R-BTA-211178", "name": "Phosphorylated FOXO1A is excluded from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042680" ], "products": [ "species_10044088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127" ] }, "reaction_10071769": { "compartment": "compartment_7660", "id": "reaction_10071769", "reactome": "R-BTA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071589", "species_10071585" ], "products": [ "species_10071591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082240", "ENSBTAT00000022288", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071640": { "compartment": "compartment_7660", "id": "reaction_10071640", "reactome": "R-BTA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10071626" ], "products": [ "species_113582", "species_10071603" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592" ] }, "reaction_10071628": { "compartment": "compartment_7660", "id": "reaction_10071628", "reactome": "R-BTA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10071624" ], "products": [ "species_10071626" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071630": { "compartment": "compartment_7660", "id": "reaction_10071630", "reactome": "R-BTA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10071767": { "compartment": "compartment_7660", "id": "reaction_10071767", "reactome": "R-BTA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071599", "species_10071595" ], "products": [ "species_10071624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001867", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071607": { "compartment": "compartment_7660", "id": "reaction_10071607", "reactome": "R-BTA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071591", "species_10039892", "species_10071603" ], "products": [ "species_10071605" ], "modifiers": [], "additional_components": [ "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3ZBW4", "ENSBTAT00000007967", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071622": { "compartment": "compartment_7660", "id": "reaction_10071622", "reactome": "R-BTA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071605" ], "products": [ "species_10071619" ], "modifiers": [ [ "species_10071605", "catalyst" ] ], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071638": { "compartment": "compartment_7660", "id": "reaction_10071638", "reactome": "R-BTA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071634", "species_10071619" ], "products": [ "species_10071636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012365", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "E1BF15", "ENSBTAT00000012365", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071617": { "compartment": "compartment_7660", "id": "reaction_10071617", "reactome": "R-BTA-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10071613" ], "products": [ "species_10071615" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10071765": { "compartment": "compartment_7660", "id": "reaction_10071765", "reactome": "R-BTA-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071611", "species_10071595" ], "products": [ "species_10071613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076740", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10047196": { "compartment": "compartment_70101", "id": "reaction_10047196", "reactome": "R-BTA-390595", "name": "Calcium Binds Troponin-C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10047192" ], "products": [ "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047198": { "compartment": "compartment_70101", "id": "reaction_10047198", "reactome": "R-BTA-390597", "name": "Release Of ADP From Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047181" ], "products": [ "species_29370", "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047200": { "compartment": "compartment_70101", "id": "reaction_10047200", "reactome": "R-BTA-390598", "name": "Myosin Binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047194" ], "products": [ "species_10047177" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10047186": { "compartment": "compartment_70101", "id": "reaction_10047186", "reactome": "R-BTA-390593", "name": "ATP Hydrolysis By Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047177" ], "products": [ "species_29372", "species_10047181" ], "modifiers": [ [ "species_10047183", "catalyst" ] ], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10071824": { "compartment": "compartment_70101", "id": "reaction_10071824", "reactome": "R-BTA-5577237", "name": "KCNH2:KCNE transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071821", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1LSF6", "ENSBTAT00000067149" ] }, "reaction_10077468": { "compartment": "compartment_984", "id": "reaction_10077468", "reactome": "R-BTA-6784598", "name": "NPPA(124-151) binds NPR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071836", "species_10077464" ], "products": [ "species_10077466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008819", "E1BN71", "ENSBTAT00000008184", "E1BN71", "ENSBTAT00000008184", "P07501", "ENSBTAT00000008819" ] }, "reaction_10071843": { "compartment": "compartment_876", "id": "reaction_10071843", "reactome": "R-BTA-5578783", "name": "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071828" ], "products": [ "species_10071830", "species_10071836", "species_10071834", "species_10071832" ], "modifiers": [ [ "species_10071840", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000085692" ] }, "reaction_10071819": { "compartment": "compartment_876", "id": "reaction_10071819", "reactome": "R-BTA-5577234", "name": "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071816", "catalyst" ] ], "additional_components": [ "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "A0A3Q1LV43", "ENSBTAT00000072593", "A0A3Q1M5I5", "ENSBTAT00000066696" ] }, "reaction_10053180": { "compartment": "compartment_876", "id": "reaction_10053180", "reactome": "R-BTA-936897", "name": "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_113592", "species_83910" ], "products": [ "species_29372", "species_29804", "species_29370", "species_74113" ], "modifiers": [ [ "species_10053175", "catalyst" ], [ "species_10053178", "inhibitor" ] ], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10091759": { "compartment": "compartment_984", "id": "reaction_10091759", "reactome": "R-BTA-9684068", "name": "ATP1A:ATP1B:FXYD binds cardiac glycosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053175", "species_9684063" ], "products": [ "species_10053178" ], "modifiers": [], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10048787": { "compartment": "compartment_12045", "id": "reaction_10048787", "reactome": "R-BTA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10048770", "catalyst" ], [ "species_10048785", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10047893": { "compartment": "compartment_876", "id": "reaction_10047893", "reactome": "R-BTA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10047890", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077323" ] }, "reaction_10071876": { "compartment": "compartment_70101", "id": "reaction_10071876", "reactome": "R-BTA-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071873", "catalyst" ] ], "additional_components": [ "E1BEH3", "ENSBTAT00000004382", "A0A3Q1MT89", "ENSBTAT00000075452", "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182" ] }, "reaction_10035579": { "compartment": "compartment_12045", "id": "reaction_10035579", "reactome": "R-BTA-74872", "name": "RDH10,11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_10035564" ], "products": [ "species_70106", "species_10035566", "species_29364" ], "modifiers": [ [ "species_10035576", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q8HZT6", "ENSBTAT00000026830", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10065597": { "compartment": "compartment_12045", "id": "reaction_10065597", "reactome": "R-BTA-2454081", "name": "RDH5 oxidises 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_29360" ], "products": [ "species_70106", "species_10035566", "species_73473" ], "modifiers": [ [ "species_10065594", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q27979", "ENSBTAT00000065932" ] }, "reaction_10065644": { "compartment": "compartment_70101", "id": "reaction_10065644", "reactome": "R-BTA-2454264", "name": "11cROL binds to RLBP1 to form RLBP1:11cROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_10035562" ], "products": [ "species_10035564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_2473611" ] }, "reaction_10035406": { "compartment": "compartment_2514888", "id": "reaction_10035406", "reactome": "R-BTA-74101", "name": "Photons induce isomerization of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10035401" ], "products": [ "species_10035404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10065646": { "compartment": "compartment_70101", "id": "reaction_10065646", "reactome": "R-BTA-2464809", "name": "RBP3 regulates the transport of atROL from ROS to RPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473615" ], "products": [ "species_2473604" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10088914": { "compartment": "compartment_70101", "id": "reaction_10088914", "reactome": "R-BTA-8960973", "name": "RLBP1:11cRAL dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035566" ], "products": [ "species_8960974", "species_10035562" ], "modifiers": [], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_32737", "ENSBTAT00000047900" ] }, "reaction_10065604": { "compartment": "compartment_70101", "id": "reaction_10065604", "reactome": "R-BTA-2454113", "name": "RBP3 transports 11cRAL to rod photoreceptor outer segment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8960974" ], "products": [ "species_32737" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10077751": { "compartment": "compartment_12045", "id": "reaction_10077751", "reactome": "R-BTA-6786239", "name": "CYP4V2 omega-hydroxylates DHA to HDoHE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6786220", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6786225" ], "modifiers": [ [ "species_10077748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085962" ] }, "reaction_10035558": { "compartment": "compartment_70101", "id": "reaction_10035558", "reactome": "R-BTA-74843", "name": "atROL binds RBP1 to form RBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473604" ], "products": [ "species_10035556" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065606": { "compartment": "compartment_70101", "id": "reaction_10065606", "reactome": "R-BTA-2454118", "name": "11cRAL binds to opsin to form 11c-retinyl:RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2565923", "species_32737" ], "products": [ "species_29356", "species_10035401" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10049433": { "compartment": "compartment_876", "id": "reaction_10049433", "reactome": "R-BTA-442317", "name": "ZIP6 and ZIP14 mediate zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065246" ] }, "reaction_10049464": { "compartment": "compartment_876", "id": "reaction_10049464", "reactome": "R-BTA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049461", "catalyst" ] ], "additional_components": [ "Q3SYU3", "ENSBTAT00000034015", "E1BEU4", "ENSBTAT00000001238", "A0A3Q1LWM2", "ENSBTAT00000075196" ] }, "reaction_10049440": { "compartment": "compartment_876", "id": "reaction_10049440", "reactome": "R-BTA-442387", "name": "ZIP8 mediates zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049437", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007448" ] }, "reaction_10049447": { "compartment": "compartment_12045", "id": "reaction_10049447", "reactome": "R-BTA-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049444", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010771" ] }, "reaction_10071469": { "compartment": "compartment_70101", "id": "reaction_10071469", "reactome": "R-BTA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10071466", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006554" ] }, "reaction_10070735": { "compartment": "compartment_70101", "id": "reaction_10070735", "reactome": "R-BTA-5226964", "name": "ANKH transports PPi from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294" ], "products": [ "species_113542" ], "modifiers": [ [ "species_10070732", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017818" ] }, "reaction_10071280": { "compartment": "compartment_984", "id": "reaction_10071280", "reactome": "R-BTA-5252072", "name": "AZGP1 binds PIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071266", "species_10071276" ], "products": [ "species_10071278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037204", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "A0A452DK44", "ENSBTAT00000037204" ] }, "reaction_10071490": { "compartment": "compartment_70101", "id": "reaction_10071490", "reactome": "R-BTA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071487", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065645" ] }, "reaction_10087365": { "compartment": "compartment_70101", "id": "reaction_10087365", "reactome": "R-BTA-8941543", "name": "VRAC heteromer transports I-, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941540" ], "products": [ "species_8941541" ], "modifiers": [ [ "species_10087362", "catalyst" ] ], "additional_components": [ "species_352022", "species_209785", "species_209785", "species_352022", "A4IFE5", "ENSBTAT00000027912", "Q08E42", "ENSBTAT00000084512", "F6PRJ0", "ENSBTAT00000005636", "A5PK13", "ENSBTAT00000085971" ] }, "reaction_10071476": { "compartment": "compartment_70101", "id": "reaction_10071476", "reactome": "R-BTA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071473", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012110" ] }, "reaction_10086343": { "compartment": "compartment_70101", "id": "reaction_10086343", "reactome": "R-BTA-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10086340", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:32551", "species_113530", "species_113530", "species_29612", "CHEBI:32551", "ENSBTAT00000018143" ] }, "reaction_10071462": { "compartment": "compartment_70101", "id": "reaction_10071462", "reactome": "R-BTA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071459", "catalyst" ] ], "additional_components": [ "F1N136", "ENSBTAT00000002985" ] }, "reaction_10047930": { "compartment": "compartment_70101", "id": "reaction_10047930", "reactome": "R-BTA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10047927", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N569", "ENSBTAT00000072103" ] }, "reaction_10065369": { "compartment": "compartment_70101", "id": "reaction_10065369", "reactome": "R-BTA-2395869", "name": "NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065371": { "compartment": "compartment_70101", "id": "reaction_10065371", "reactome": "R-BTA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065386": { "compartment": "compartment_70101", "id": "reaction_10065386", "reactome": "R-BTA-2395965", "name": "NUDT18 hydrolyses 8-OH-dADP to 8-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395963", "species_29356" ], "products": [ "species_29372", "species_2395964" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065359": { "compartment": "compartment_70101", "id": "reaction_10065359", "reactome": "R-BTA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065760": { "compartment": "compartment_7660", "id": "reaction_10065760", "reactome": "R-BTA-2509793", "name": "NUDT16 hydrolyses dIDP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509796" ], "products": [ "species_113550", "species_2509805" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065328": { "compartment": "compartment_5460", "id": "reaction_10065328", "reactome": "R-BTA-2393954", "name": "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2393945", "species_113521" ], "products": [ "species_2393950", "species_159448" ], "modifiers": [ [ "species_10065325", "catalyst" ] ], "additional_components": [ "A7MBI8", "ENSBTAT00000015090", "species_29926" ] }, "reaction_10065763": { "compartment": "compartment_7660", "id": "reaction_10065763", "reactome": "R-BTA-2509816", "name": "NUDT16 hydrolyses IDP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509811" ], "products": [ "species_113550", "species_2509792" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065362": { "compartment": "compartment_70101", "id": "reaction_10065362", "reactome": "R-BTA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065378": { "compartment": "compartment_70101", "id": "reaction_10065378", "reactome": "R-BTA-2395873", "name": "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395880" ], "products": [ "species_29372", "species_2395877" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065381": { "compartment": "compartment_70101", "id": "reaction_10065381", "reactome": "R-BTA-2395876", "name": "NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065383": { "compartment": "compartment_70101", "id": "reaction_10065383", "reactome": "R-BTA-2395879", "name": "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065319": { "compartment": "compartment_70101", "id": "reaction_10065319", "reactome": "R-BTA-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10065316", "catalyst" ] ], "additional_components": [ "species_29926", "F1MMR8", "ENSBTAT00000068724" ] }, "reaction_10072489": { "compartment": "compartment_70101", "id": "reaction_10072489", "reactome": "R-BTA-5624131", "name": "UNC119B binds myristoylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072485", "species_10072480" ], "products": [ "species_10072487" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007584", "ENSBTAT00000009843", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10072497": { "compartment": "compartment_18730", "id": "reaction_10072497", "reactome": "R-BTA-5624132", "name": "UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072487" ], "products": [ "species_10072495" ], "modifiers": [], "additional_components": [ "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10033379": { "compartment": "compartment_7660", "id": "reaction_10033379", "reactome": "R-BTA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10033367" ], "modifiers": [ [ "species_10033377", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083861", "E1BG94", "ENSBTAT00000005182", "E1BD75", "ENSBTAT00000023554" ] }, "reaction_10033412": { "compartment": "compartment_70101", "id": "reaction_10033412", "reactome": "R-BTA-68712", "name": "The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10033390" ], "products": [ "species_10033410", "species_10033388" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336", "Q56JZ0", "ENSBTAT00000023040", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000067336" ] }, "reaction_10085788": { "compartment": "compartment_70101", "id": "reaction_10085788", "reactome": "R-BTA-8873794", "name": "PCTP binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075605", "species_1524163" ], "products": [ "species_10085786" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024898", "species_429785", "P02720", "ENSBTAT00000024898" ] }, "reaction_10086064": { "compartment": "compartment_12045", "id": "reaction_10086064", "reactome": "R-BTA-8877153", "name": "STARD7 binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10086060" ], "products": [ "species_10086062" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071992", "A0A3Q1LZP9", "ENSBTAT00000071992", "species_429785" ] }, "reaction_10085808": { "compartment": "compartment_70101", "id": "reaction_10085808", "reactome": "R-BTA-8873923", "name": "STARD10 binds LPCAT1 and PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035781", "species_426925", "species_10085792" ], "products": [ "species_10085794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001250", "ENSBTAT00000071421", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10085024": { "compartment": "compartment_984", "id": "reaction_10085024", "reactome": "R-BTA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10085021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017353" ] }, "reaction_10059141": { "compartment": "compartment_12045", "id": "reaction_10059141", "reactome": "R-BTA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10059138", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "species_29926", "A0A3Q1LV95", "ENSBTAT00000067199", "E1BLQ9", "ENSBTAT00000012081" ] }, "reaction_10059063": { "compartment": "compartment_70101", "id": "reaction_10059063", "reactome": "R-BTA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10059060", "catalyst" ] ], "additional_components": [ "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10085798": { "compartment": "compartment_70101", "id": "reaction_10085798", "reactome": "R-BTA-8873834", "name": "STARD10 transports PC from ER membrane to lamellar body membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085794" ], "products": [ "species_10085796", "species_10035781" ], "modifiers": [], "additional_components": [ "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "ENSBTAT00000001250" ] }, "reaction_10059094": { "compartment": "compartment_70101", "id": "reaction_10059094", "reactome": "R-BTA-1483159", "name": "PCho is dephosphorylated to Cho by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524071" ], "products": [ "species_264618", "species_29372" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10090489": { "compartment": "compartment_70101", "id": "reaction_10090489", "reactome": "R-BTA-9026780", "name": "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10090480": { "compartment": "compartment_70101", "id": "reaction_10090480", "reactome": "R-BTA-9026777", "name": "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10039964", "catalyst" ] ], "additional_components": [ "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425" ] }, "reaction_10090491": { "compartment": "compartment_70101", "id": "reaction_10090491", "reactome": "R-BTA-9026911", "name": "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024768" ], "products": [ "species_9026915" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10044835": { "compartment": "compartment_70101", "id": "reaction_10044835", "reactome": "R-BTA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10044837": { "compartment": "compartment_70101", "id": "reaction_10044837", "reactome": "R-BTA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10076360": { "compartment": "compartment_876", "id": "reaction_10076360", "reactome": "R-BTA-5693681", "name": "DUOX1,2 reduce O2 to H2O2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352327" ], "products": [ "species_351628", "species_351629" ], "modifiers": [ [ "species_10076357", "catalyst" ] ], "additional_components": [ "E1BMK1", "ENSBTAT00000021618", "E1BMS3", "ENSBTAT00000021603" ] }, "reaction_10043978": { "compartment": "compartment_876", "id": "reaction_10043978", "reactome": "R-BTA-209910", "name": "Iodide is taken up by thyroid epithelial cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10044828": { "compartment": "compartment_984", "id": "reaction_10044828", "reactome": "R-BTA-350901", "name": "Iodide is organified", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_209818", "species_351629" ], "products": [ "species_109276", "species_351630", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043980": { "compartment": "compartment_984", "id": "reaction_10043980", "reactome": "R-BTA-209925", "name": "DIT and MIT combine to form triiodothyronine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329", "species_351639" ], "products": [ "species_352331", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10043986": { "compartment": "compartment_984", "id": "reaction_10043986", "reactome": "R-BTA-209973", "name": "Tyrosine is diiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352030", "species_209818", "species_351629" ], "products": [ "species_109276", "species_352329", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043924": { "compartment": "compartment_984", "id": "reaction_10043924", "reactome": "R-BTA-209815", "name": "Tyrosine is monoiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351630", "species_352030" ], "products": [ "species_622410", "species_351639" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043956": { "compartment": "compartment_984", "id": "reaction_10043956", "reactome": "R-BTA-209840", "name": "Two DITs combine to form thyroxine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329" ], "products": [ "species_352326", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10066745": { "compartment": "compartment_7660", "id": "reaction_10066745", "reactome": "R-BTA-3222128", "name": "NOC2L binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066741" ], "products": [ "species_10066743" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021980", "Q3SYU1", "ENSBTAT00000021980", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066712": { "compartment": "compartment_7660", "id": "reaction_10066712", "reactome": "R-BTA-3222020", "name": "NUAK1 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066701" ], "products": [ "species_113582", "species_10066709", "species_10066690", "species_10066699" ], "modifiers": [ [ "species_10066701", "catalyst" ] ], "additional_components": [ "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081563": { "compartment": "compartment_7660", "id": "reaction_10081563", "reactome": "R-BTA-6805035", "name": "TP53 binds STK11 and NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066694", "species_10066677", "species_10066690" ], "products": [ "species_10066696" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013805", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10081595": { "compartment": "compartment_7660", "id": "reaction_10081595", "reactome": "R-BTA-6805276", "name": "CDK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10081585" ], "modifiers": [ [ "species_10081592", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064" ] }, "reaction_10080730": { "compartment": "compartment_7660", "id": "reaction_10080730", "reactome": "R-BTA-6799431", "name": "TP53 binds HIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080726", "species_10066677" ], "products": [ "species_10080728" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015051", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BQ34", "ENSBTAT00000015051" ] }, "reaction_10081629": { "compartment": "compartment_7660", "id": "reaction_10081629", "reactome": "R-BTA-6805479", "name": "TP53RK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081626", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000039179" ] }, "reaction_10066704": { "compartment": "compartment_7660", "id": "reaction_10066704", "reactome": "R-BTA-3222006", "name": "STK11 (LKB1) phosphorylates NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066696" ], "products": [ "species_113582", "species_10066701" ], "modifiers": [ [ "species_10066696", "catalyst" ] ], "additional_components": [ "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10080722": { "compartment": "compartment_7660", "id": "reaction_10080722", "reactome": "R-BTA-6799409", "name": "HIPK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066668" ], "products": [ "species_113582", "species_10066659", "species_10066666", "species_10078728" ], "modifiers": [ [ "species_10066668", "catalyst" ] ], "additional_components": [ "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "P67939", "ENSBTAT00000001420", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066870": { "compartment": "compartment_7660", "id": "reaction_10066870", "reactome": "R-BTA-3239014", "name": "MAPKAPK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10066862" ], "modifiers": [ [ "species_10066867", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10081622": { "compartment": "compartment_7660", "id": "reaction_10081622", "reactome": "R-BTA-6805470", "name": "AMPK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081619", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10078731": { "compartment": "compartment_7660", "id": "reaction_10078731", "reactome": "R-BTA-6798374", "name": "DYRK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033524" ], "products": [ "species_113582", "species_10078728" ], "modifiers": [ [ "species_10078718", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000009545" ] }, "reaction_10066670": { "compartment": "compartment_7660", "id": "reaction_10066670", "reactome": "R-BTA-3215251", "name": "TP53INP1 and HIPK2 bind TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066659", "species_10066666" ], "products": [ "species_10066668" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078720": { "compartment": "compartment_7660", "id": "reaction_10078720", "reactome": "R-BTA-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10078714" ], "products": [ "species_113582", "species_10078718" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009545", "ENSBTAT00000009545", "ENSBTAT00000040104" ] }, "reaction_10081602": { "compartment": "compartment_7660", "id": "reaction_10081602", "reactome": "R-BTA-6805285", "name": "PLK3 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10081599", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000008055" ] }, "reaction_10039801": { "compartment": "compartment_7660", "id": "reaction_10039801", "reactome": "R-BTA-174097", "name": "Association of Emi1 with Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039797" ], "products": [ "species_10039799" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "Q32L05", "ENSBTAT00000074490", "Q32L05", "ENSBTAT00000074490", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10039852": { "compartment": "compartment_7660", "id": "reaction_10039852", "reactome": "R-BTA-174235", "name": "Association of Emi1 with Cdc20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039803" ], "products": [ "species_10039850" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "ENSBTAT00000077512", "F1MRW5", "ENSBTAT00000077512", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10038033": { "compartment": "compartment_70101", "id": "reaction_10038033", "reactome": "R-BTA-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038027" ], "products": [ "species_10038031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10038035": { "compartment": "compartment_70101", "id": "reaction_10038035", "reactome": "R-BTA-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038019", "species_10038015", "species_10038027" ], "products": [ "species_10038029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000057027", "ENSBTAT00000009521", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MWP1", "ENSBTAT00000009521", "Q1JQB2", "ENSBTAT00000057027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10033833": { "compartment": "compartment_70101", "id": "reaction_10033833", "reactome": "R-BTA-70903", "name": "urocanate + H2O => 4-imidazolone-5-propionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30721" ], "products": [ "species_34979" ], "modifiers": [ [ "species_10033830", "catalyst" ] ], "additional_components": [ "species_29360", "A0A3Q1LXH7", "ENSBTAT00000083727" ] }, "reaction_10033849": { "compartment": "compartment_70101", "id": "reaction_10033849", "reactome": "R-BTA-70920", "name": "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30158", "species_111355" ], "products": [ "species_29404", "species_70919" ], "modifiers": [ [ "species_10033846", "catalyst" ] ], "additional_components": [ "A0A3Q1MBB6", "ENSBTAT00000074746" ] }, "reaction_10054585": { "compartment": "compartment_70101", "id": "reaction_10054585", "reactome": "R-BTA-977301", "name": "Histidine is decarboxylated to histamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612" ], "products": [ "species_175992", "species_113528" ], "modifiers": [ [ "species_10054582", "catalyst" ] ], "additional_components": [ "Q5EA83", "ENSBTAT00000013083" ] }, "reaction_10077758": { "compartment": "compartment_70101", "id": "reaction_10077758", "reactome": "R-BTA-6786245", "name": "CARNS1 transforms ATP, L-His, b-Ala to CARN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612", "species_113592", "species_73590" ], "products": [ "species_6786250", "species_29372", "species_29370" ], "modifiers": [ [ "species_10077755", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023529" ] }, "reaction_10086033": { "compartment": "compartment_70101", "id": "reaction_10086033", "reactome": "R-BTA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10086030", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010790" ] }, "reaction_10033840": { "compartment": "compartment_70101", "id": "reaction_10033840", "reactome": "R-BTA-70906", "name": "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34979" ], "products": [ "species_30158", "species_70106" ], "modifiers": [ [ "species_10033837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021647" ] }, "reaction_10059066": { "compartment": "compartment_70616", "id": "reaction_10059066", "reactome": "R-BTA-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524072", "species_1524067" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10092237": { "compartment": "compartment_7660", "id": "reaction_10092237", "reactome": "R-BTA-9707523", "name": "Hemes bind to BACH1:MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707575", "species_10092233" ], "products": [ "species_10055987", "species_10092235" ], "modifiers": [], "additional_components": [ "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092269": { "compartment": "compartment_70101", "id": "reaction_10092269", "reactome": "R-BTA-9708423", "name": "XPO1:BACH1:Hemes are transported out of the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092259" ], "products": [ "species_10092267" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092239": { "compartment": "compartment_7660", "id": "reaction_10092239", "reactome": "R-BTA-9707690", "name": "BACH1 binds MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231", "species_10055987" ], "products": [ "species_10092233" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092271": { "compartment": "compartment_7660", "id": "reaction_10092271", "reactome": "R-BTA-9708430", "name": "XPO1 (CRM1) binds to BACH1:Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092235", "species_10050265" ], "products": [ "species_10092259" ], "modifiers": [], "additional_components": [ "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092225": { "compartment": "compartment_984", "id": "reaction_10092225", "reactome": "R-BTA-9707505", "name": "Hemes bind to CLEC1B dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10092221" ], "products": [ "species_10092223" ], "modifiers": [], "additional_components": [ "species_71185", "E1BLL1", "ENSBTAT00000053034", "E1BLL1", "ENSBTAT00000053034", "species_71185" ] }, "reaction_10092227": { "compartment": "compartment_984", "id": "reaction_10092227", "reactome": "R-BTA-9707516", "name": "FeHM dissociates from MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743" ], "products": [ "species_917955", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10052914": { "compartment": "compartment_876", "id": "reaction_10052914", "reactome": "R-BTA-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "species_71185", "ENSBTAT00000035283" ] }, "reaction_10092214": { "compartment": "compartment_984", "id": "reaction_10092214", "reactome": "R-BTA-9707504", "name": "H2O2 oxidises ferrohemoglobin to MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_351629" ], "products": [ "species_10064743", "species_9707624", "species_9707647" ], "modifiers": [ [ "species_10092212", "inhibitor" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10081561": { "compartment": "compartment_7660", "id": "reaction_10081561", "reactome": "R-BTA-6804762", "name": "TP53 forms homotetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066422" ], "products": [ "species_10066677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10091685": { "compartment": "compartment_7660", "id": "reaction_10091685", "reactome": "R-BTA-9670114", "name": "Histone H3.3 deposition at telomere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091677", "species_10035227" ], "products": [ "species_10091683", "species_10040161" ], "modifiers": [], "additional_components": [ "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000034695", "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000033058" ] }, "reaction_10038540": { "compartment": "compartment_7660", "id": "reaction_10038540", "reactome": "R-BTA-163099", "name": "Alignment Of The RNA Template On The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038538" ], "products": [ "species_10038529" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10038947": { "compartment": "compartment_7660", "id": "reaction_10038947", "reactome": "R-BTA-164617", "name": "Elongation of Extended Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10038531", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10038542" ], "modifiers": [ [ "species_10038531", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038949": { "compartment": "compartment_7660", "id": "reaction_10038949", "reactome": "R-BTA-164620", "name": "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038531" ], "products": [ "species_10038531" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038534": { "compartment": "compartment_7660", "id": "reaction_10038534", "reactome": "R-BTA-163090", "name": "Elongation Of The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_30185", "species_10038529", "species_29892", "species_29604" ], "products": [ "species_10038531" ], "modifiers": [ [ "species_10038529", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10087577": { "compartment": "compartment_17957", "id": "reaction_10087577", "reactome": "R-BTA-8944242", "name": "Association of procollagen type XXVII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062035" ], "products": [ "species_10062840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081723", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10087579": { "compartment": "compartment_17957", "id": "reaction_10087579", "reactome": "R-BTA-8944246", "name": "Association of procollagen type XXI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062810" ], "products": [ "species_10062812" ], "modifiers": [], "additional_components": [ "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1MQC5", "ENSBTAT00000074238" ] }, "reaction_10087581": { "compartment": "compartment_17957", "id": "reaction_10087581", "reactome": "R-BTA-8944247", "name": "Association of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060135", "species_10060159", "species_10060111" ], "products": [ "species_10060183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025663", "ENSBTAT00000018479", "ENSBTAT00000015668", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087583": { "compartment": "compartment_17957", "id": "reaction_10087583", "reactome": "R-BTA-8944250", "name": "Association of procollagen type XXV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062400" ], "products": [ "species_10062823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087569": { "compartment": "compartment_17957", "id": "reaction_10087569", "reactome": "R-BTA-8944219", "name": "Association of procollagen type XVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062025" ], "products": [ "species_10062790" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065364", "G3MXK9", "ENSBTAT00000065364" ] }, "reaction_10087571": { "compartment": "compartment_17957", "id": "reaction_10087571", "reactome": "R-BTA-8944220", "name": "Association of procollagen type XXIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062031" ], "products": [ "species_10062821" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017548", "F1MSJ7", "ENSBTAT00000017548" ] }, "reaction_10087573": { "compartment": "compartment_17957", "id": "reaction_10087573", "reactome": "R-BTA-8944223", "name": "Association of procollagen type V", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062017", "species_10062045", "species_10062041" ], "products": [ "species_10062749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063052", "ENSBTAT00000013440", "ENSBTAT00000084344", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052" ] }, "reaction_10062071": { "compartment": "compartment_17957", "id": "reaction_10062071", "reactome": "R-BTA-2002401", "name": "Association of procollagen type XVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062037" ], "products": [ "species_10062069" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067622", "A0A3Q1LYA4", "ENSBTAT00000067622" ] }, "reaction_10087563": { "compartment": "compartment_17957", "id": "reaction_10087563", "reactome": "R-BTA-8944215", "name": "Association of procollagen type XX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062027" ], "products": [ "species_10062801" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063888", "G3N021", "ENSBTAT00000063888" ] }, "reaction_10087565": { "compartment": "compartment_17957", "id": "reaction_10087565", "reactome": "R-BTA-8944216", "name": "Association of procollagen type XV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062023" ], "products": [ "species_10062781" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10087567": { "compartment": "compartment_17957", "id": "reaction_10087567", "reactome": "R-BTA-8944218", "name": "Association of procollagen type VIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062019", "species_10062043" ], "products": [ "species_10062763" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018159", "ENSBTAT00000083731", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159" ] }, "reaction_10087585": { "compartment": "compartment_17957", "id": "reaction_10087585", "reactome": "R-BTA-8944254", "name": "Association of procollagen type XXVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062033" ], "products": [ "species_10062832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087587": { "compartment": "compartment_17957", "id": "reaction_10087587", "reactome": "R-BTA-8944261", "name": "Association of procollagen type XIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062021" ], "products": [ "species_10062772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10087589": { "compartment": "compartment_17957", "id": "reaction_10087589", "reactome": "R-BTA-8944263", "name": "Association of procollagen type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062015" ], "products": [ "species_10062709" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505" ] }, "reaction_10044446": { "compartment": "compartment_7660", "id": "reaction_10044446", "reactome": "R-BTA-212356", "name": "Formation of CSL-NICD coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10044434", "species_10044414", "species_10044442", "species_10044410", "species_10044424" ], "products": [ "species_10044444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "A0A3Q1MLT2", "ENSBTAT00000075969", "ENSBTAT00000050083", "ENSBTAT00000010697", "ENSBTAT00000004696", "A0A3Q1MF28", "ENSBTAT00000078064", "A0A3Q1MF28", "ENSBTAT00000078064", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "G3X812", "ENSBTAT00000050083", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10044726": { "compartment": "compartment_7660", "id": "reaction_10044726", "reactome": "R-BTA-350058", "name": "Formation of CSL NCOR corepressor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10044722", "species_10044704", "species_10044442", "species_10044410" ], "products": [ "species_10044724" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000010697", "ENSBTAT00000004696", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092287": { "compartment": "compartment_7660", "id": "reaction_10092287", "reactome": "R-BTA-9708517", "name": "FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10092281" ], "products": [ "species_10092277", "species_10092284", "species_10086712" ], "modifiers": [ [ "species_10092281", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000069043", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092273": { "compartment": "compartment_70101", "id": "reaction_10092273", "reactome": "R-BTA-9708466", "name": "BACH1 translocates from the nucleoplasm to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231" ], "products": [ "species_10092261" ], "modifiers": [ [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000005416" ] }, "reaction_10092289": { "compartment": "compartment_7660", "id": "reaction_10092289", "reactome": "R-BTA-9708525", "name": "BACH1:FBXL17 binds SCF(SKP2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092279", "species_10086712" ], "products": [ "species_10092281" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092293": { "compartment": "compartment_7660", "id": "reaction_10092293", "reactome": "R-BTA-9708557", "name": "FBXL17 binds BACH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092277", "species_10092233" ], "products": [ "species_10092279", "species_10055987" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069043", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702" ] }, "reaction_10057639": { "compartment": "compartment_876", "id": "reaction_10057639", "reactome": "R-BTA-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057636", "catalyst" ] ], "additional_components": [ "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182", "E1B9M4", "ENSBTAT00000014309" ] }, "reaction_10065673": { "compartment": "compartment_70101", "id": "reaction_10065673", "reactome": "R-BTA-2465919", "name": "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_200993" ], "products": [ "species_10065666", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "CHEBI:16254", "ENSBTAT00000074877" ] }, "reaction_10091560": { "compartment": "compartment_70101", "id": "reaction_10091560", "reactome": "R-BTA-9656893", "name": "OPN1MW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065675": { "compartment": "compartment_70101", "id": "reaction_10065675", "reactome": "R-BTA-2465924", "name": "OPN1LW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065677": { "compartment": "compartment_70101", "id": "reaction_10065677", "reactome": "R-BTA-2465934", "name": "11cROL translocates from Muller cells to cone photoreceptor cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473606" ], "products": [ "species_2473611" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065679": { "compartment": "compartment_70101", "id": "reaction_10065679", "reactome": "R-BTA-2465938", "name": "RBP3 regulates atROL taken up by Muller cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473607" ], "products": [ "species_2473617" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065664": { "compartment": "compartment_74000", "id": "reaction_10065664", "reactome": "R-BTA-2465917", "name": "Photons induce isomerisation of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065654", "species_419777" ], "products": [ "species_10065662" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10065683": { "compartment": "compartment_70101", "id": "reaction_10065683", "reactome": "R-BTA-2465971", "name": "RLBP1 binds atROL to form RLBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473617", "species_10035562" ], "products": [ "species_10065681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_975590" ] }, "reaction_10065687": { "compartment": "compartment_70101", "id": "reaction_10065687", "reactome": "R-BTA-2466085", "name": "at-retinyl is hydrolysed from R* to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10065662" ], "products": [ "species_10065685", "species_975622" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10091558": { "compartment": "compartment_70101", "id": "reaction_10091558", "reactome": "R-BTA-9656891", "name": "OPN1SW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048190", "species_32737" ], "products": [ "species_10065652", "species_29356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021912", "ENSBTAT00000021912" ] }, "reaction_10068899": { "compartment": "compartment_7660", "id": "reaction_10068899", "reactome": "R-BTA-3857336", "name": "CEBPB homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068891" ], "products": [ "species_10068893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086463", "A0A3Q1NLC4", "ENSBTAT00000086463" ] }, "reaction_10040355": { "compartment": "compartment_70101", "id": "reaction_10040355", "reactome": "R-BTA-182594", "name": "Association of INK4 family proteins with CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040351", "species_10040345" ], "products": [ "species_10040353" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10088026": { "compartment": "compartment_984", "id": "reaction_10088026", "reactome": "R-BTA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10088023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009888" ] }, "reaction_10058910": { "compartment": "compartment_12045", "id": "reaction_10058910", "reactome": "R-BTA-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524028" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058871": { "compartment": "compartment_12045", "id": "reaction_10058871", "reactome": "R-BTA-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975614" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10057007": { "compartment": "compartment_70101", "id": "reaction_10057007", "reactome": "R-BTA-1237042", "name": "AQP1 tetramer transports CO2 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237009" ], "products": [ "species_113528" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10081968": { "compartment": "compartment_70101", "id": "reaction_10081968", "reactome": "R-BTA-6806831", "name": "CYB5Rs reduce MetHb to HbA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081949", "species_73473" ], "products": [ "species_70106", "species_10081955", "species_29360" ], "modifiers": [ [ "species_10081965", "catalyst" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "A0A3Q1LIS5", "ENSBTAT00000068812", "A0A3Q1MXD6", "ENSBTAT00000072609" ] }, "reaction_10058790": { "compartment": "compartment_70101", "id": "reaction_10058790", "reactome": "R-BTA-1475435", "name": "CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057062": { "compartment": "compartment_70101", "id": "reaction_10057062", "reactome": "R-BTA-1237325", "name": "Hemoglobin A is protonated and carbamated causing release of oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057046", "species_70106", "species_113528" ], "products": [ "species_10057060", "species_29368" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10037739": { "compartment": "compartment_70101", "id": "reaction_10037739", "reactome": "R-BTA-140216", "name": "Translocation of PMAIP1 (NOXA) to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037735" ], "products": [ "species_10037737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071269", "ENSBTAT00000071269" ] }, "reaction_10058985": { "compartment": "compartment_70616", "id": "reaction_10058985", "reactome": "R-BTA-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524083", "species_1498773" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058955": { "compartment": "compartment_70616", "id": "reaction_10058955", "reactome": "R-BTA-1482781", "name": "MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524075", "species_1498773" ], "products": [ "species_1524072", "species_1524079" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058993": { "compartment": "compartment_12045", "id": "reaction_10058993", "reactome": "R-BTA-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1524069" ], "products": [ "species_1524081", "species_76194" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10058998": { "compartment": "compartment_12045", "id": "reaction_10058998", "reactome": "R-BTA-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10045466": { "compartment": "compartment_204883", "id": "reaction_10045466", "reactome": "R-BTA-375342", "name": "Connexin 36 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045463", "catalyst" ] ], "additional_components": [ "Q866T7", "ENSBTAT00000028966" ] }, "reaction_10045455": { "compartment": "compartment_876", "id": "reaction_10045455", "reactome": "R-BTA-375340", "name": "Connexin 62 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045452", "catalyst" ] ], "additional_components": [ "E1BLU3", "ENSBTAT00000015039" ] }, "reaction_10045444": { "compartment": "compartment_876", "id": "reaction_10045444", "reactome": "R-BTA-375339", "name": "Pannexin 1/Pannexin2 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045441", "catalyst" ] ], "additional_components": [ "D7R519", "ENSBTAT00000015932", "G5E5X7", "ENSBTAT00000037612" ] }, "reaction_10084238": { "compartment": "compartment_262783", "id": "reaction_10084238", "reactome": "R-BTA-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084234" ], "products": [ "species_10084236" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "G3N3N1", "ENSBTAT00000063023", "species_29438", "G3N3N1", "ENSBTAT00000063023", "species_29438", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084291": { "compartment": "compartment_5683628", "id": "reaction_10084291", "reactome": "R-BTA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084286" ], "products": [ "species_29372", "species_10084288" ], "modifiers": [ [ "species_10084286", "catalyst" ], [ "species_10084272", "catalyst" ] ], "additional_components": [ "E1BJA0", "ENSBTAT00000083670", "species_29438", "E1BJA0", "ENSBTAT00000083670", "species_29420", "E1BJA0", "ENSBTAT00000083670", "species_29438", "ENSBTAT00000012236" ] }, "reaction_10084261": { "compartment": "compartment_17938", "id": "reaction_10084261", "reactome": "R-BTA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084252" ], "products": [ "species_29372", "species_10084254" ], "modifiers": [ [ "species_10084252", "catalyst" ], [ "species_10084259", "catalyst" ] ], "additional_components": [ "species_29438", "Q08DE8", "ENSBTAT00000016976", "Q08DE8", "ENSBTAT00000016976", "species_29420", "species_29438", "Q08DE8", "ENSBTAT00000016976", "ENSBTAT00000082752" ] }, "reaction_10084228": { "compartment": "compartment_19363", "id": "reaction_10084228", "reactome": "R-BTA-8854209", "name": "TBC1D10A binds JFC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084220" ], "products": [ "species_10084226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "ENSBTAT00000077895", "A0A3Q1M443", "ENSBTAT00000077895", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084276": { "compartment": "compartment_5683628", "id": "reaction_10084276", "reactome": "R-BTA-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084272", "species_10084268" ], "products": [ "species_10084274" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012236", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "E1BHZ5", "ENSBTAT00000012236" ] }, "reaction_10084246": { "compartment": "compartment_20699", "id": "reaction_10084246", "reactome": "R-BTA-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084242", "species_10083720" ], "products": [ "species_10084244" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061025", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N746", "ENSBTAT00000061025" ] }, "reaction_10044801": { "compartment": "compartment_70101", "id": "reaction_10044801", "reactome": "R-BTA-350604", "name": "Agmatine + H2O <=> putrescine + urea", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_351164" ], "products": [ "species_29514", "species_29610" ], "modifiers": [ [ "species_10044798", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085149" ] }, "reaction_10041177": { "compartment": "compartment_70101", "id": "reaction_10041177", "reactome": "R-BTA-192051", "name": "CYP7A1 7-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192114" ], "modifiers": [ [ "species_10041174", "catalyst" ] ], "additional_components": [ "E1BM29", "ENSBTAT00000006957" ] }, "reaction_10041500": { "compartment": "compartment_70101", "id": "reaction_10041500", "reactome": "R-BTA-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194634", "species_29364" ], "products": [ "species_29356", "species_29366", "species_194644", "species_29460" ], "modifiers": [ [ "species_10041497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002582" ] }, "reaction_10041206": { "compartment": "compartment_5460", "id": "reaction_10041206", "reactome": "R-BTA-192123", "name": "CYP27A1 27-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193840", "species_113600" ], "products": [ "species_113563", "species_193846", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10044232": { "compartment": "compartment_70101", "id": "reaction_10044232", "reactome": "R-BTA-211951", "name": "CYP1B1 4-hydroxylates EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_211973" ], "modifiers": [ [ "species_10044229", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075887", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10041195": { "compartment": "compartment_70101", "id": "reaction_10041195", "reactome": "R-BTA-192065", "name": "CYP7B1 7-hydroxylates 25OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_192148", "species_29364" ], "products": [ "species_29356", "species_192184", "species_29366" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10043964": { "compartment": "compartment_70101", "id": "reaction_10043964", "reactome": "R-BTA-209845", "name": "CYP2R1 25-hydroxylates VD3 to 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_8963870", "species_29364" ], "products": [ "species_8963879", "species_29356", "species_29366" ], "modifiers": [ [ "species_10043961", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084891" ] }, "reaction_10044225": { "compartment": "compartment_5460", "id": "reaction_10044225", "reactome": "R-BTA-211950", "name": "CYP24A1 24-hydroxylates CTL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_215607", "species_113600" ], "products": [ "species_113563", "species_215622", "species_113521" ], "modifiers": [ [ "species_10043907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10043971": { "compartment": "compartment_70101", "id": "reaction_10043971", "reactome": "R-BTA-209868", "name": "CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209804", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_209800", "species_29366" ], "modifiers": [ [ "species_10043968", "catalyst" ], [ "species_29532", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022485" ] }, "reaction_10044293": { "compartment": "compartment_12045", "id": "reaction_10044293", "reactome": "R-BTA-212007", "name": "CYP26A1,B1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10044280": { "compartment": "compartment_12045", "id": "reaction_10044280", "reactome": "R-BTA-212005", "name": "CYP2F1 dehydrogenates 3-methylindole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_213162", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213163" ], "modifiers": [ [ "species_10044277", "catalyst" ] ], "additional_components": [ "G3MYW0", "ENSBTAT00000063781" ] }, "reaction_10044218": { "compartment": "compartment_12045", "id": "reaction_10044218", "reactome": "R-BTA-211929", "name": "CYP2C19 5-hydroxylates omeprazole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211892", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211944" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044250": { "compartment": "compartment_12045", "id": "reaction_10044250", "reactome": "R-BTA-211966", "name": "CYP2D6 4-hydroxylates debrisoquine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211993", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211952" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10044477": { "compartment": "compartment_12045", "id": "reaction_10044477", "reactome": "R-BTA-213175", "name": "CYP3A4,5 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_156522", "species_113601" ], "products": [ "species_113519", "species_113564", "species_156523" ], "modifiers": [ [ "species_10044474", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044223": { "compartment": "compartment_12045", "id": "reaction_10044223", "reactome": "R-BTA-211948", "name": "CYP3A4 can N-demethylate loperamide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_213155" ], "products": [ "species_113519", "species_113564", "species_213151" ], "modifiers": [ [ "species_10044220", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10035865": { "compartment": "compartment_17960", "id": "reaction_10035865", "reactome": "R-BTA-76426", "name": "N-atom dealkylation of caffeine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_40727", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76424" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10035861": { "compartment": "compartment_17960", "id": "reaction_10035861", "reactome": "R-BTA-76373", "name": "N-hydroxylation of 4-aminobiphenyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_47687", "species_113601" ], "products": [ "species_113519", "species_113564", "species_34889" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10044275": { "compartment": "compartment_12045", "id": "reaction_10044275", "reactome": "R-BTA-212004", "name": "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_211939" ], "products": [ "species_113519", "species_113564", "species_211927" ], "modifiers": [ [ "species_10044272", "catalyst" ] ], "additional_components": [ "F1MRH2", "ENSBTAT00000040300" ] }, "reaction_10044182": { "compartment": "compartment_12045", "id": "reaction_10044182", "reactome": "R-BTA-211882", "name": "CYP3A7 can 6beta-hydroxylate testosterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044179", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10035977": { "compartment": "compartment_12045", "id": "reaction_10035977", "reactome": "R-BTA-76472", "name": "Ethylene is oxidized to Ethylene oxide by CYP1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_38985", "species_113601" ], "products": [ "species_113519", "species_113564", "species_38987" ], "modifiers": [ [ "species_10035962", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061300", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10044265": { "compartment": "compartment_12045", "id": "reaction_10044265", "reactome": "R-BTA-211988", "name": "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211855", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211937" ], "modifiers": [ [ "species_10044262", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159" ] }, "reaction_10044204": { "compartment": "compartment_12045", "id": "reaction_10044204", "reactome": "R-BTA-211910", "name": "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211906", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211894" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044270": { "compartment": "compartment_12045", "id": "reaction_10044270", "reactome": "R-BTA-211991", "name": "Cyclophosphamide is 4-hydroxylated by CYP2B6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211977", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211967" ], "modifiers": [ [ "species_10044267", "catalyst" ] ], "additional_components": [ "A0A3Q1MU42", "ENSBTAT00000079854" ] }, "reaction_10044167": { "compartment": "compartment_12045", "id": "reaction_10044167", "reactome": "R-BTA-211881", "name": "Coumarin is 7-hydroxylated by CYP2A13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10044164", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10035911": { "compartment": "compartment_12045", "id": "reaction_10035911", "reactome": "R-BTA-76456", "name": "O-atom dealkylation of dextromethorphan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_39703", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76455" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10035878": { "compartment": "compartment_12045", "id": "reaction_10035878", "reactome": "R-BTA-76453", "name": "Coumarin is 7-hydroxylated by CYP2A6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10035875", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10059035": { "compartment": "compartment_12045", "id": "reaction_10059035", "reactome": "R-BTA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10059032", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "Q17QM4", "ENSBTAT00000010310" ] }, "reaction_10059082": { "compartment": "compartment_70101", "id": "reaction_10059082", "reactome": "R-BTA-1483096", "name": "PETA is dephosphorylated to ETA by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428686" ], "products": [ "species_29372", "species_1498751" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10059130": { "compartment": "compartment_12045", "id": "reaction_10059130", "reactome": "R-BTA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10059127", "catalyst" ] ], "additional_components": [ "A0A3Q1MLB5", "ENSBTAT00000070509" ] }, "reaction_10059150": { "compartment": "compartment_70101", "id": "reaction_10059150", "reactome": "R-BTA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10059147", "catalyst" ] ], "additional_components": [ "F1MRD9", "ENSBTAT00000024637", "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10076994": { "compartment": "compartment_5460", "id": "reaction_10076994", "reactome": "R-BTA-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696414", "species_113521" ], "products": [ "species_113548", "species_113532", "species_5693978" ], "modifiers": [ [ "species_10076991", "catalyst" ] ], "additional_components": [ "Q5E9S4", "ENSBTAT00000013587" ] }, "reaction_10077004": { "compartment": "compartment_12045", "id": "reaction_10077004", "reactome": "R-BTA-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10058892": { "compartment": "compartment_12045", "id": "reaction_10058892", "reactome": "R-BTA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10059006": { "compartment": "compartment_12045", "id": "reaction_10059006", "reactome": "R-BTA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10058894": { "compartment": "compartment_12045", "id": "reaction_10058894", "reactome": "R-BTA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058961": { "compartment": "compartment_12045", "id": "reaction_10058961", "reactome": "R-BTA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058819": { "compartment": "compartment_12045", "id": "reaction_10058819", "reactome": "R-BTA-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_1500593", "species_76116" ], "modifiers": [ [ "species_10058816", "catalyst" ] ], "additional_components": [ "A0A3Q1LUK0", "ENSBTAT00000073448" ] }, "reaction_10058948": { "compartment": "compartment_12045", "id": "reaction_10058948", "reactome": "R-BTA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10083572": { "compartment": "compartment_12045", "id": "reaction_10083572", "reactome": "R-BTA-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10083569", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010259" ] }, "reaction_10038938": { "compartment": "compartment_7660", "id": "reaction_10038938", "reactome": "R-BTA-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038932", "species_164121" ], "products": [ "species_10038936" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10083614": { "compartment": "compartment_984", "id": "reaction_10083614", "reactome": "R-BTA-8848663", "name": "ADIPOQ trimer binds ADIPOR dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083610", "species_10083594" ], "products": [ "species_10083612" ], "modifiers": [], "additional_components": [ "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795", "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795" ] }, "reaction_10060553": { "compartment": "compartment_172574", "id": "reaction_10060553", "reactome": "R-BTA-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060537": { "compartment": "compartment_172574", "id": "reaction_10060537", "reactome": "R-BTA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060468": { "compartment": "compartment_172574", "id": "reaction_10060468", "reactome": "R-BTA-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_29372", "species_1806195" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10088526": { "compartment": "compartment_5460", "id": "reaction_10088526", "reactome": "R-BTA-8952903", "name": "ADPRHL2 hydrolyses poly(ADP-ribose)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8952909", "species_113521" ], "products": [ "species_8952909", "species_8952905" ], "modifiers": [ [ "species_10088523", "catalyst" ] ], "additional_components": [ "species_8870342", "species_8870342", "ENSBTAT00000028950" ] }, "reaction_10037674": { "compartment": "compartment_70101", "id": "reaction_10037674", "reactome": "R-BTA-139899", "name": "Sequestration of BAD protein by 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10037644" ], "products": [ "species_10037672" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000016610", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10037678": { "compartment": "compartment_70101", "id": "reaction_10037678", "reactome": "R-BTA-139905", "name": "Translocation of activated BAD protein to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037676" ], "products": [ "species_10037626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "ENSBTAT00000016610" ] }, "reaction_10037630": { "compartment": "compartment_17906", "id": "reaction_10037630", "reactome": "R-BTA-139897", "name": "BAD displaces tBID from BCL-2 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037626", "species_10037275" ], "products": [ "species_10037269", "species_10037628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "F6R2C4", "ENSBTAT00000025701", "F1MUT9", "ENSBTAT00000016610" ] }, "reaction_10047900": { "compartment": "compartment_114521", "id": "reaction_10047900", "reactome": "R-BTA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10047897", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158" ] }, "reaction_10076824": { "compartment": "compartment_17906", "id": "reaction_10076824", "reactome": "R-BTA-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696066", "species_5696069" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10076821", "catalyst" ] ], "additional_components": [ "species_6814795", "species_6797635", "species_1524101", "species_417891", "A0A3Q1MFM9", "ENSBTAT00000074114", "species_29926" ] }, "reaction_10085340": { "compartment": "compartment_70101", "id": "reaction_10085340", "reactome": "R-BTA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10085337", "catalyst" ] ], "additional_components": [ "E1B9I9", "ENSBTAT00000013851", "A0A3Q1MUM3", "ENSBTAT00000079883", "A0A3Q1N293", "ENSBTAT00000069345" ] }, "reaction_10059091": { "compartment": "compartment_12045", "id": "reaction_10059091", "reactome": "R-BTA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10059088", "catalyst" ] ], "additional_components": [ "species_29926", "G3MZU2", "ENSBTAT00000065725" ] }, "reaction_10059044": { "compartment": "compartment_12045", "id": "reaction_10059044", "reactome": "R-BTA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10059041", "catalyst" ] ], "additional_components": [ "Q3T103", "ENSBTAT00000010454", "species_29926", "species_113527" ] }, "reaction_10071344": { "compartment": "compartment_876", "id": "reaction_10071344", "reactome": "R-BTA-5333678", "name": "CPNEs bind PL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071340", "species_171142" ], "products": [ "species_10071342" ], "modifiers": [ [ "species_74016", "catalyst" ] ], "additional_components": [ "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644", "species_171142", "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10059849": { "compartment": "compartment_984", "id": "reaction_10059849", "reactome": "R-BTA-1602374", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_33625" ], "products": [ "species_1602419", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058943": { "compartment": "compartment_12045", "id": "reaction_10058943", "reactome": "R-BTA-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10085310": { "compartment": "compartment_12045", "id": "reaction_10085310", "reactome": "R-BTA-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_392417", "species_1500646" ], "products": [ "species_33625", "species_1806234" ], "modifiers": [ [ "species_10085307", "catalyst" ] ], "additional_components": [ "A0A3Q1MI45", "ENSBTAT00000070851", "F1MFD9", "ENSBTAT00000012114", "A0A3Q1LWY5", "ENSBTAT00000073265" ] }, "reaction_10058945": { "compartment": "compartment_12045", "id": "reaction_10058945", "reactome": "R-BTA-1482776", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058880": { "compartment": "compartment_12045", "id": "reaction_10058880", "reactome": "R-BTA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10058916": { "compartment": "compartment_12045", "id": "reaction_10058916", "reactome": "R-BTA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10059014": { "compartment": "compartment_12045", "id": "reaction_10059014", "reactome": "R-BTA-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059016": { "compartment": "compartment_12045", "id": "reaction_10059016", "reactome": "R-BTA-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059018": { "compartment": "compartment_12045", "id": "reaction_10059018", "reactome": "R-BTA-1482907", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058826": { "compartment": "compartment_70616", "id": "reaction_10058826", "reactome": "R-BTA-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10059021": { "compartment": "compartment_12045", "id": "reaction_10059021", "reactome": "R-BTA-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058877": { "compartment": "compartment_12045", "id": "reaction_10058877", "reactome": "R-BTA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058812": { "compartment": "compartment_12045", "id": "reaction_10058812", "reactome": "R-BTA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058913": { "compartment": "compartment_70616", "id": "reaction_10058913", "reactome": "R-BTA-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10058983": { "compartment": "compartment_70616", "id": "reaction_10058983", "reactome": "R-BTA-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524047", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10059847": { "compartment": "compartment_984", "id": "reaction_10059847", "reactome": "R-BTA-1602368", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602402" ], "products": [ "species_1602415", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058934": { "compartment": "compartment_70616", "id": "reaction_10058934", "reactome": "R-BTA-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524027", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10058809": { "compartment": "compartment_12045", "id": "reaction_10058809", "reactome": "R-BTA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058970": { "compartment": "compartment_12045", "id": "reaction_10058970", "reactome": "R-BTA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10058829": { "compartment": "compartment_12045", "id": "reaction_10058829", "reactome": "R-BTA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058990": { "compartment": "compartment_12045", "id": "reaction_10058990", "reactome": "R-BTA-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058987", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059856": { "compartment": "compartment_984", "id": "reaction_10059856", "reactome": "R-BTA-1602399", "name": "PC is hydrolyzed to 1-acyl LPC by PLB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10059858": { "compartment": "compartment_984", "id": "reaction_10059858", "reactome": "R-BTA-1602417", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10085826": { "compartment": "compartment_12045", "id": "reaction_10085826", "reactome": "R-BTA-8874435", "name": "THEM86B hydrolyses PMCHO, PMETAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8874447" ], "products": [ "species_8874450", "species_5696116" ], "modifiers": [ [ "species_10085823", "catalyst" ] ], "additional_components": [ "CHEBI:17810", "CHEBI:17476", "CHEBI:36313", "CHEBI:36314", "ENSBTAT00000076823" ] }, "reaction_10058996": { "compartment": "compartment_12045", "id": "reaction_10058996", "reactome": "R-BTA-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524021", "species_975614" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059121": { "compartment": "compartment_12045", "id": "reaction_10059121", "reactome": "R-BTA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10059118", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018461" ] }, "reaction_10059073": { "compartment": "compartment_12045", "id": "reaction_10059073", "reactome": "R-BTA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10059070", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077015" ] }, "reaction_10059101": { "compartment": "compartment_70616", "id": "reaction_10059101", "reactome": "R-BTA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10059098", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007970" ] }, "reaction_10057390": { "compartment": "compartment_876", "id": "reaction_10057390", "reactome": "R-BTA-1296043", "name": "Activation of HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057387", "catalyst" ] ], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10057607": { "compartment": "compartment_876", "id": "reaction_10057607", "reactome": "R-BTA-1297444", "name": "Binding of cAMP to HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10057385" ], "products": [ "species_10057387" ], "modifiers": [], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10049326": { "compartment": "compartment_876", "id": "reaction_10049326", "reactome": "R-BTA-433104", "name": "NACT co-transports trivalent citrate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433138", "species_74113" ], "products": [ "species_76190", "species_83910" ], "modifiers": [ [ "species_10049323", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006144" ] }, "reaction_10049333": { "compartment": "compartment_876", "id": "reaction_10049333", "reactome": "R-BTA-433114", "name": "NaS1 co-transports sulphate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_74113" ], "products": [ "species_83910", "species_174375" ], "modifiers": [ [ "species_10049330", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078998" ] }, "reaction_10051305": { "compartment": "compartment_876", "id": "reaction_10051305", "reactome": "R-BTA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10051302", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "species_561052", "species_561052", "CHEBI:104011", "F1MIJ1", "ENSBTAT00000018132", "G3N1R8", "ENSBTAT00000064695", "F1MII8", "ENSBTAT00000018139" ] }, "reaction_10051314": { "compartment": "compartment_876", "id": "reaction_10051314", "reactome": "R-BTA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10051311", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068956" ] }, "reaction_10051307": { "compartment": "compartment_876", "id": "reaction_10051307", "reactome": "R-BTA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051325": { "compartment": "compartment_876", "id": "reaction_10051325", "reactome": "R-BTA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10051322", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016935" ] }, "reaction_10051276": { "compartment": "compartment_876", "id": "reaction_10051276", "reactome": "R-BTA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10051273", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013203" ] }, "reaction_10051283": { "compartment": "compartment_876", "id": "reaction_10051283", "reactome": "R-BTA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051269": { "compartment": "compartment_876", "id": "reaction_10051269", "reactome": "R-BTA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10051286": { "compartment": "compartment_876", "id": "reaction_10051286", "reactome": "R-BTA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10067993": { "compartment": "compartment_7660", "id": "reaction_10067993", "reactome": "R-BTA-3371537", "name": "DBC1 binds SIRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048710", "species_10067989" ], "products": [ "species_10067991" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018630", "ENSBTAT00000007194", "E1B9H3", "ENSBTAT00000007194", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10071241": { "compartment": "compartment_70101", "id": "reaction_10071241", "reactome": "R-BTA-5251959", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10071123" ], "products": [ "species_29372", "species_10071232" ], "modifiers": [ [ "species_10071238", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q27975", "ENSBTAT00000017500", "species_29370", "Q3MI00", "ENSBTAT00000036270", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437" ] }, "reaction_10068008": { "compartment": "compartment_7660", "id": "reaction_10068008", "reactome": "R-BTA-3371567", "name": "DBC1 is phosphorylated by ATM/ART", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10067995" ], "products": [ "species_113582", "species_10067989" ], "modifiers": [ [ "species_10068005", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007194", "ENSBTAT00000007194", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1M8V1", "ENSBTAT00000066572" ] }, "reaction_10071208": { "compartment": "compartment_7660", "id": "reaction_10071208", "reactome": "R-BTA-5251955", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10071171" ], "products": [ "species_113550", "species_10071169", "species_10071195" ], "modifiers": [ [ "species_10071205", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q56JY0", "ENSBTAT00000026632", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_29370", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437", "Q3MI00", "ENSBTAT00000036270" ] }, "reaction_10071313": { "compartment": "compartment_70101", "id": "reaction_10071313", "reactome": "R-BTA-5252079", "name": "HSP110s exchange ATP for ADP on HSP70s:ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071232", "species_113592" ], "products": [ "species_10071123", "species_29370" ], "modifiers": [ [ "species_10071304", "catalyst" ], [ "species_10071311", "inhibitor" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_29370", "Q27975", "ENSBTAT00000017500", "species_113592", "Q0IIM3", "ENSBTAT00000006600", "Q148J7", "ENSBTAT00000023720", "Q3ZBG5", "ENSBTAT00000007039", "F1MIU2", "ENSBTAT00000018131", "F1MSS9", "ENSBTAT00000017468", "A0A3Q1MQM3", "ENSBTAT00000074682" ] }, "reaction_10071127": { "compartment": "compartment_70101", "id": "reaction_10071127", "reactome": "R-BTA-5251942", "name": "Hikeshi binds HSP70s:ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071123", "species_10071069" ], "products": [ "species_10071125" ], "modifiers": [], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "ENSBTAT00000026632", "Q56JY0", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_113592" ] }, "reaction_10092312": { "compartment": "compartment_70616", "id": "reaction_10092312", "reactome": "R-BTA-9709406", "name": "CO binds to Cytochrome c oxidase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9709326", "species_10038606" ], "products": [ "species_10038645" ], "modifiers": [], "additional_components": [ "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10040636": { "compartment": "compartment_70101", "id": "reaction_10040636", "reactome": "R-BTA-189398", "name": "HMOX1 dimer, HMOX2 cleave heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364", "species_71185" ], "products": [ "species_29356", "species_189385", "species_71067", "species_189396", "species_29366" ], "modifiers": [ [ "species_10040633", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047056" ] }, "reaction_10047807": { "compartment": "compartment_7660", "id": "reaction_10047807", "reactome": "R-BTA-400143", "name": "Fatty acid ligands activate PPARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047799", "species_10047793", "species_10047777" ], "products": [ "species_10047797", "species_10047805", "species_10047771" ], "modifiers": [], "additional_components": [ "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "P80425", "ENSBTAT00000024032", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068", "B7TCI5", "ENSBTAT00000084466", "Q5EA13", "ENSBTAT00000068423", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000024032", "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "Q5EA13", "ENSBTAT00000068423", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092308": { "compartment": "compartment_984", "id": "reaction_10092308", "reactome": "R-BTA-9709317", "name": "CO binds to free ferrohemoglobin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_9709335" ], "products": [ "species_10092212" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10092310": { "compartment": "compartment_984", "id": "reaction_10092310", "reactome": "R-BTA-9709360", "name": "H2O2 reduces MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_351629" ], "products": [ "species_109276", "species_10092210", "species_352327" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10067416": { "compartment": "compartment_70101", "id": "reaction_10067416", "reactome": "R-BTA-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067409" ], "products": [ "species_10067413", "species_10067395" ], "modifiers": [ [ "species_10067409", "catalyst" ] ], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_29426", "species_3299744", "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10056408": { "compartment": "compartment_1222693", "id": "reaction_10056408", "reactome": "R-BTA-1222376", "name": "NOX2 generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_70106", "species_1222424", "species_29366" ], "modifiers": [ [ "species_10056405", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "species_71185", "O46521", "ENSBTAT00000067849", "species_113596" ] }, "reaction_10076891": { "compartment": "compartment_5460", "id": "reaction_10076891", "reactome": "R-BTA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10076888", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045076" ] }, "reaction_10087866": { "compartment": "compartment_70101", "id": "reaction_10087866", "reactome": "R-BTA-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068573" ], "products": [ "species_10067409" ], "modifiers": [], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067388": { "compartment": "compartment_984", "id": "reaction_10067388", "reactome": "R-BTA-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_3299686" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10067385", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10068575": { "compartment": "compartment_70101", "id": "reaction_10068575", "reactome": "R-BTA-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067407", "species_10068571" ], "products": [ "species_10068573" ], "modifiers": [], "additional_components": [ "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10069854": { "compartment": "compartment_17963", "id": "reaction_10069854", "reactome": "R-BTA-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069852" ], "products": [ "species_10067385" ], "modifiers": [], "additional_components": [ "F6R4N7", "ENSBTAT00000018580", "species_29426", "species_209799", "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10067731": { "compartment": "compartment_5460", "id": "reaction_10067731", "reactome": "R-BTA-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_1655882", "species_113600" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10067728", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10080786": { "compartment": "compartment_984", "id": "reaction_10080786", "reactome": "R-BTA-6799695", "name": "GPX5,6 reduce H2O2 to H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_1247892" ], "products": [ "species_109276", "species_3341331" ], "modifiers": [ [ "species_10080783", "catalyst" ] ], "additional_components": [ "A0A3Q1M7E3", "ENSBTAT00000068263", "F1MCF5", "ENSBTAT00000015939" ] }, "reaction_10067735": { "compartment": "compartment_70616", "id": "reaction_10067735", "reactome": "R-BTA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10038548" ], "products": [ "species_10038546", "species_189461" ], "modifiers": [], "additional_components": [ "P62894", "ENSBTAT00000007918", "CHEBI:38574", "CHEBI:38573", "P62894", "ENSBTAT00000007918" ] }, "reaction_10034166": { "compartment": "compartment_70101", "id": "reaction_10034166", "reactome": "R-BTA-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29450", "species_29366" ], "modifiers": [ [ "species_10034163", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10067722": { "compartment": "compartment_5460", "id": "reaction_10067722", "reactome": "R-BTA-3322995", "name": "PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_1614617" ], "products": [ "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067719", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "P35705", "ENSBTAT00000011505", "Q9BGI1", "ENSBTAT00000011403" ] }, "reaction_10068716": { "compartment": "compartment_17927", "id": "reaction_10068716", "reactome": "R-BTA-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10068713", "catalyst" ] ], "additional_components": [ "species_209799", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067375": { "compartment": "compartment_5460", "id": "reaction_10067375", "reactome": "R-BTA-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_3299683" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10067372", "catalyst" ] ], "additional_components": [ "E1BHL1", "ENSBTAT00000008569", "species_113527" ] }, "reaction_10067744": { "compartment": "compartment_70101", "id": "reaction_10067744", "reactome": "R-BTA-3343700", "name": "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_29408" ], "products": [ "species_29356", "species_111745" ], "modifiers": [ [ "species_10067741", "catalyst" ] ], "additional_components": [ "O77834", "ENSBTAT00000006383", "A0A3Q1LMV5", "ENSBTAT00000084460" ] }, "reaction_10068578": { "compartment": "compartment_5460", "id": "reaction_10068578", "reactome": "R-BTA-3697894", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_3697881" ], "products": [ "species_3697842", "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "ENSBTAT00000011403" ] }, "reaction_10067398": { "compartment": "compartment_70101", "id": "reaction_10067398", "reactome": "R-BTA-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29368", "species_29408" ], "modifiers": [ [ "species_10067395", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10066873": { "compartment": "compartment_7660", "id": "reaction_10066873", "reactome": "R-BTA-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066855", "species_29358" ], "products": [ "species_113582", "species_10066867" ], "modifiers": [ [ "species_10066855", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10066779": { "compartment": "compartment_7660", "id": "reaction_10066779", "reactome": "R-BTA-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_113671" ], "products": [ "species_10066770", "species_159939" ], "modifiers": [ [ "species_10066776", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10066876": { "compartment": "compartment_7660", "id": "reaction_10066876", "reactome": "R-BTA-3240295", "name": "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066770" ], "products": [ "species_77502", "species_10066768" ], "modifiers": [ [ "species_10044327", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10066832": { "compartment": "compartment_7660", "id": "reaction_10066832", "reactome": "R-BTA-3229089", "name": "PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_10066828" ], "products": [ "species_10066830" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179" ] }, "reaction_10066857": { "compartment": "compartment_7660", "id": "reaction_10066857", "reactome": "R-BTA-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066853" ], "products": [ "species_113582", "species_10066855" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10066786": { "compartment": "compartment_70101", "id": "reaction_10066786", "reactome": "R-BTA-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10066783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "ENSBTAT00000011949" ] }, "reaction_10088964": { "compartment": "compartment_7660", "id": "reaction_10088964", "reactome": "R-BTA-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066774", "species_111793" ], "products": [ "species_10066776" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063022", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10076298": { "compartment": "compartment_7660", "id": "reaction_10076298", "reactome": "R-BTA-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074450" ], "products": [ "species_113582", "species_10076295", "species_10074441" ], "modifiers": [ [ "species_10074450", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10074429": { "compartment": "compartment_7660", "id": "reaction_10074429", "reactome": "R-BTA-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074417", "species_10074425" ], "products": [ "species_10074427" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074431": { "compartment": "compartment_7660", "id": "reaction_10074431", "reactome": "R-BTA-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_3785706" ], "products": [ "species_10074417" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074446": { "compartment": "compartment_7660", "id": "reaction_10074446", "reactome": "R-BTA-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074438", "species_29358" ], "products": [ "species_113582", "species_10074443", "species_10074441" ], "modifiers": [ [ "species_10074438", "catalyst" ] ], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10078369": { "compartment": "compartment_7660", "id": "reaction_10078369", "reactome": "R-BTA-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074427" ], "products": [ "species_10074438", "species_2485002" ], "modifiers": [ [ "species_10074427", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074453": { "compartment": "compartment_7660", "id": "reaction_10074453", "reactome": "R-BTA-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074448" ], "products": [ "species_2485002", "species_10074450" ], "modifiers": [ [ "species_10074448", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10069684": { "compartment": "compartment_7660", "id": "reaction_10069684", "reactome": "R-BTA-4647593", "name": "EP400 binds CDKN1A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069680", "species_10069676" ], "products": [ "species_10069682" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000027216", "F1MLB1", "ENSBTAT00000027216", "P67939", "ENSBTAT00000001420" ] }, "reaction_10076343": { "compartment": "compartment_7660", "id": "reaction_10076343", "reactome": "R-BTA-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074425" ], "products": [ "species_10074448" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10068854": { "compartment": "compartment_7660", "id": "reaction_10068854", "reactome": "R-BTA-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_75165" ], "products": [ "species_10068852" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10066630": { "compartment": "compartment_7660", "id": "reaction_10066630", "reactome": "R-BTA-3209159", "name": "Phosphorylated ERF translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066626" ], "products": [ "species_10066628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000437", "ENSBTAT00000000437" ] }, "reaction_10091401": { "compartment": "compartment_17938", "id": "reaction_10091401", "reactome": "R-BTA-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091329" ], "products": [ "species_29372", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ], [ "species_10091399", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3B7L5", "ENSBTAT00000010532", "A0A3Q1MS15", "ENSBTAT00000083520", "A0A3Q1NF19", "ENSBTAT00000067422" ] }, "reaction_10091336": { "compartment": "compartment_17938", "id": "reaction_10091336", "reactome": "R-BTA-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10091329" ], "products": [ "species_29438", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091354": { "compartment": "compartment_17938", "id": "reaction_10091354", "reactome": "R-BTA-9640168", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091344" ], "products": [ "species_10091342", "species_10091338" ], "modifiers": [], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530" ] }, "reaction_10091356": { "compartment": "compartment_17938", "id": "reaction_10091356", "reactome": "R-BTA-9640175", "name": "v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091333", "species_10091338" ], "products": [ "species_10091340" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091404": { "compartment": "compartment_17938", "id": "reaction_10091404", "reactome": "R-BTA-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039057", "species_10091358" ], "products": [ "species_10091360" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091365": { "compartment": "compartment_17938", "id": "reaction_10091365", "reactome": "R-BTA-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091360" ], "products": [ "species_29372", "species_10091362" ], "modifiers": [ [ "species_10091360", "catalyst" ] ], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091351": { "compartment": "compartment_17938", "id": "reaction_10091351", "reactome": "R-BTA-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091340" ], "products": [ "species_29420", "species_10091344" ], "modifiers": [ [ "species_10091340", "catalyst" ], [ "species_10091349", "inhibitor" ] ], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "ENSBTAT00000087052" ] }, "reaction_10073481": { "compartment": "compartment_70101", "id": "reaction_10073481", "reactome": "R-BTA-5662986", "name": "MT2A binds copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_3299744" ], "products": [ "species_10073479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_3299744", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073464": { "compartment": "compartment_70101", "id": "reaction_10073464", "reactome": "R-BTA-5662613", "name": "MT3 exchanges zinc for copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073444", "species_209799" ], "products": [ "species_10073462", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "P37359", "ENSBTAT00000022460", "species_29426", "species_3299744", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073468": { "compartment": "compartment_70101", "id": "reaction_10073468", "reactome": "R-BTA-5662620", "name": "MT3 binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_1132098" ], "products": [ "species_10073466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_1132098", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073460": { "compartment": "compartment_70101", "id": "reaction_10073460", "reactome": "R-BTA-5662608", "name": "MT2A binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_1132098" ], "products": [ "species_10073458" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_1132098", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073446": { "compartment": "compartment_70101", "id": "reaction_10073446", "reactome": "R-BTA-5662606", "name": "MT3 binds zinc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_29426" ], "products": [ "species_10073444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_29426", "P37359", "ENSBTAT00000022460" ] }, "reaction_10075304": { "compartment": "compartment_7660", "id": "reaction_10075304", "reactome": "R-BTA-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075297" ], "products": [ "species_10075301", "species_30555" ], "modifiers": [ [ "species_10075297", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075323": { "compartment": "compartment_7660", "id": "reaction_10075323", "reactome": "R-BTA-5687673", "name": "MRN recruits LIG3:XRCC1 to MMEJ sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036900", "species_10075316" ], "products": [ "species_10075321" ], "modifiers": [], "additional_components": [ "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075306": { "compartment": "compartment_7660", "id": "reaction_10075306", "reactome": "R-BTA-5687465", "name": "MRN complex binds RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074778" ], "products": [ "species_10075297" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075326": { "compartment": "compartment_7660", "id": "reaction_10075326", "reactome": "R-BTA-5687675", "name": "LIG3 ligates remaining SSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075321" ], "products": [ "species_10035718", "species_10036900", "species_10074778", "species_5687670" ], "modifiers": [ [ "species_10075321", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075319": { "compartment": "compartment_7660", "id": "reaction_10075319", "reactome": "R-BTA-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075312" ], "products": [ "species_10075316", "species_68454", "species_10036890" ], "modifiers": [ [ "species_10075312", "catalyst" ] ], "additional_components": [ "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000000071", "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10086350": { "compartment": "compartment_876", "id": "reaction_10086350", "reactome": "R-BTA-8932955", "name": "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189227", "species_74113" ], "products": [ "species_83910", "species_189254" ], "modifiers": [ [ "species_10086347", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_188995", "species_70113", "species_70113", "species_188995", "ENSBTAT00000084455", "ENSBTAT00000055483" ] }, "reaction_10057350": { "compartment": "compartment_876", "id": "reaction_10057350", "reactome": "R-BTA-1296024", "name": "Activation of ATP sensitive Potassium channels in neuroendocrine cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057347", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q2KHY6", "ENSBTAT00000003307", "A2VDS4", "ENSBTAT00000021523", "E1BKR6", "ENSBTAT00000046676" ] }, "reaction_10057399": { "compartment": "compartment_876", "id": "reaction_10057399", "reactome": "R-BTA-1296045", "name": "Activation of Potassium transport channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057396", "catalyst" ] ], "additional_components": [ "A0A3Q1N684", "ENSBTAT00000081253" ] }, "reaction_10033473": { "compartment": "compartment_7660", "id": "reaction_10033473", "reactome": "R-BTA-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033469" ], "products": [ "species_10033471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083861", "ENSBTAT00000083861" ] }, "reaction_10084497": { "compartment": "compartment_7660", "id": "reaction_10084497", "reactome": "R-BTA-8857692", "name": "RNA demethylases demethylate N6-methyladenosine RNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8857725", "species_113671", "species_111793" ], "products": [ "species_8857850", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10084494", "catalyst" ] ], "additional_components": [ "species_71067", "A0A3Q1N5P9", "ENSBTAT00000081168", "A0A452DJ48", "ENSBTAT00000034976" ] }, "reaction_10090466": { "compartment": "compartment_70101", "id": "reaction_10090466", "reactome": "R-BTA-9025152", "name": "ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025151" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "CHEBI:138674", "CHEBI:138673", "ENSBTAT00000015911" ] }, "reaction_10090468": { "compartment": "compartment_70101", "id": "reaction_10090468", "reactome": "R-BTA-9025957", "name": "ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025960" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090477": { "compartment": "compartment_70101", "id": "reaction_10090477", "reactome": "R-BTA-9026408", "name": "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026407" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090470": { "compartment": "compartment_70101", "id": "reaction_10090470", "reactome": "R-BTA-9026003", "name": "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026047" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090472": { "compartment": "compartment_70101", "id": "reaction_10090472", "reactome": "R-BTA-9026006", "name": "ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026293" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090474": { "compartment": "compartment_70101", "id": "reaction_10090474", "reactome": "R-BTA-9026007", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_9026307", "species_29364" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10052888": { "compartment": "compartment_876", "id": "reaction_10052888", "reactome": "R-BTA-917807", "name": "holoTF:TFRC dimer translocates from plasma membrane to endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052876" ], "products": [ "species_10052886" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052923": { "compartment": "compartment_74700", "id": "reaction_10052923", "reactome": "R-BTA-917936", "name": "MCOLN1 transports Fe2+ from endosome lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917810" ], "products": [ "species_71067" ], "modifiers": [ [ "species_10052920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065500" ] }, "reaction_10052907": { "compartment": "compartment_70101", "id": "reaction_10052907", "reactome": "R-BTA-917814", "name": "apoTF:TFRC dimer translocates from endosome membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052903" ], "products": [ "species_10052905" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052925": { "compartment": "compartment_984", "id": "reaction_10052925", "reactome": "R-BTA-917987", "name": "TFRC dimer binds 2xholoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052874", "species_10052872" ], "products": [ "species_10052876" ], "modifiers": [], "additional_components": [ "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10052909": { "compartment": "compartment_171907", "id": "reaction_10052909", "reactome": "R-BTA-917835", "name": "Fe3+ dissociates from holoTF:TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052886" ], "products": [ "species_10052903", "species_917966" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052911": { "compartment": "compartment_947586", "id": "reaction_10052911", "reactome": "R-BTA-917839", "name": "apo-Transferrin dissociates from the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052905" ], "products": [ "species_10051000", "species_10052872" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421" ] }, "reaction_10076099": { "compartment": "compartment_876", "id": "reaction_10076099", "reactome": "R-BTA-5691154", "name": "HFE binds TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076095", "species_10052872" ], "products": [ "species_10076097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017371", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "Q5EEZ1", "ENSBTAT00000017371" ] }, "reaction_10052901": { "compartment": "compartment_171907", "id": "reaction_10052901", "reactome": "R-BTA-917811", "name": "STEAP3-like proteins reduce Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917882", "species_917966" ], "products": [ "species_917810" ], "modifiers": [ [ "species_10052898", "catalyst" ] ], "additional_components": [ "A0A3Q1LPT9", "ENSBTAT00000077862" ] }, "reaction_10036076": { "compartment": "compartment_7660", "id": "reaction_10036076", "reactome": "R-BTA-77585", "name": "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036050", "species_10036072" ], "products": [ "species_10036074" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10036052": { "compartment": "compartment_7660", "id": "reaction_10036052", "reactome": "R-BTA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036048", "species_10036044" ], "products": [ "species_10036050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10085967": { "compartment": "compartment_70101", "id": "reaction_10085967", "reactome": "R-BTA-8876312", "name": "SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876310", "species_74113" ], "products": [ "species_83910", "species_8876304" ], "modifiers": [ [ "species_10085964", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_113557", "species_373863", "species_197230", "ENSBTAT00000029140" ] }, "reaction_10048768": { "compartment": "compartment_876", "id": "reaction_10048768", "reactome": "R-BTA-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048765", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033777" ] }, "reaction_10048740": { "compartment": "compartment_876", "id": "reaction_10048740", "reactome": "R-BTA-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10048737", "catalyst" ] ], "additional_components": [ "E1BD54", "ENSBTAT00000045797", "E1B9J2", "ENSBTAT00000001818" ] }, "reaction_10052040": { "compartment": "compartment_70101", "id": "reaction_10052040", "reactome": "R-BTA-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_29432", "species_893599" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10064346": { "compartment": "compartment_984", "id": "reaction_10064346", "reactome": "R-BTA-2160492", "name": "IL4I1:FAD oxidises L-Phe to kPPV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_351993", "species_352327" ], "products": [ "species_2022135", "species_351629", "species_2160466" ], "modifiers": [ [ "species_10064343", "catalyst" ] ], "additional_components": [ "species_113596", "F1N191", "ENSBTAT00000007580" ] }, "reaction_10033935": { "compartment": "compartment_70101", "id": "reaction_10033935", "reactome": "R-BTA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10033932", "catalyst" ] ], "additional_components": [ "Q3ZBD3", "ENSBTAT00000015750" ] }, "reaction_10076974": { "compartment": "compartment_70101", "id": "reaction_10076974", "reactome": "R-BTA-5696365", "name": "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696361", "species_29356" ], "products": [ "species_29502", "species_29448", "species_5359061" ], "modifiers": [ [ "species_10076971", "catalyst" ] ], "additional_components": [ "Q32LE5", "ENSBTAT00000077904" ] }, "reaction_10033944": { "compartment": "compartment_70101", "id": "reaction_10033944", "reactome": "R-BTA-71164", "name": "homogentisate + O2 => maleylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30337" ], "products": [ "species_31135" ], "modifiers": [ [ "species_10033941", "catalyst" ] ], "additional_components": [ "A0A3Q1LS65", "ENSBTAT00000087453", "species_71067" ] }, "reaction_10033962": { "compartment": "compartment_70101", "id": "reaction_10033962", "reactome": "R-BTA-71181", "name": "fumarylacetoacetate => fumarate + acetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_31175" ], "products": [ "species_29666", "species_29586" ], "modifiers": [ [ "species_10033959", "catalyst" ] ], "additional_components": [ "A0A3Q1MPJ4", "ENSBTAT00000072597" ] }, "reaction_10033953": { "compartment": "compartment_70101", "id": "reaction_10033953", "reactome": "R-BTA-71173", "name": "maleylacetoacetate => fumarylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31135" ], "products": [ "species_31175" ], "modifiers": [ [ "species_10033950", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10075181": { "compartment": "compartment_7660", "id": "reaction_10075181", "reactome": "R-BTA-5686587", "name": "ABL1 phosphorylates RAD52", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10035844" ], "products": [ "species_113582", "species_10075178" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "A2VE43", "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617", "ENSBTAT00000080797" ] }, "reaction_10035846": { "compartment": "compartment_7660", "id": "reaction_10035846", "reactome": "R-BTA-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035842" ], "products": [ "species_10035844" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617" ] }, "reaction_10040183": { "compartment": "compartment_7660", "id": "reaction_10040183", "reactome": "R-BTA-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040167", "species_10040179", "species_10040175", "species_10040171" ], "products": [ "species_10040181" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026619", "ENSBTAT00000022773", "ENSBTAT00000012322", "ENSBTAT00000061540", "E1BC42", "ENSBTAT00000061540", "Q08E12", "ENSBTAT00000012322", "A2VE40", "ENSBTAT00000022773", "A4IFH4", "ENSBTAT00000026619" ] }, "reaction_10033504": { "compartment": "compartment_7660", "id": "reaction_10033504", "reactome": "R-BTA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10038904": { "compartment": "compartment_5460", "id": "reaction_10038904", "reactome": "R-BTA-163320", "name": "Association of mTERF with the termination sequence", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038900", "species_164569" ], "products": [ "species_10038902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063305", "G3N2I6", "ENSBTAT00000063305" ] }, "reaction_10040864": { "compartment": "compartment_12045", "id": "reaction_10040864", "reactome": "R-BTA-191072", "name": "Synthesis of Cx43", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10040862" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002398" ] }, "reaction_10055833": { "compartment": "compartment_70101", "id": "reaction_10055833", "reactome": "R-BTA-990489", "name": "Kinesin-13 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055577" ], "products": [ "species_10055579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023059", "F1N0Y3", "ENSBTAT00000023059" ] }, "reaction_10055515": { "compartment": "compartment_70101", "id": "reaction_10055515", "reactome": "R-BTA-983194", "name": "Kinesin-1 is a heterotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055511", "species_10055501" ], "products": [ "species_10055513" ], "modifiers": [], "additional_components": [ "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358" ] }, "reaction_10055645": { "compartment": "compartment_70101", "id": "reaction_10055645", "reactome": "R-BTA-983259", "name": "Kinesins move along microtubules consuming ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10055643" ], "products": [ "species_29370", "species_10055643" ], "modifiers": [], "additional_components": [ "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055823": { "compartment": "compartment_70101", "id": "reaction_10055823", "reactome": "R-BTA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055559" ], "products": [ "species_10055561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012347", "E1BF29", "ENSBTAT00000012347" ] }, "reaction_10055647": { "compartment": "compartment_70101", "id": "reaction_10055647", "reactome": "R-BTA-983266", "name": "Kinesins bind microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10055641" ], "products": [ "species_10055643" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055827": { "compartment": "compartment_70101", "id": "reaction_10055827", "reactome": "R-BTA-984671", "name": "Chromokinesins form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055825" ], "products": [ "species_10055555" ], "modifiers": [], "additional_components": [ "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936" ] }, "reaction_10055829": { "compartment": "compartment_70101", "id": "reaction_10055829", "reactome": "R-BTA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055565" ], "products": [ "species_10055567" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011898", "E1BG49", "ENSBTAT00000011898" ] }, "reaction_10055831": { "compartment": "compartment_70101", "id": "reaction_10055831", "reactome": "R-BTA-984733", "name": "Kinesin-3 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055533" ], "products": [ "species_10055535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035821", "E1BKE3", "ENSBTAT00000035821" ] }, "reaction_10090460": { "compartment": "compartment_70101", "id": "reaction_10090460", "reactome": "R-BTA-9024872", "name": "ALOX15 oxidises 17(S)-Hp-DHA to PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024012" ], "products": [ "species_9024883" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090386": { "compartment": "compartment_70101", "id": "reaction_10090386", "reactome": "R-BTA-9020262", "name": "ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024522" ], "products": [ "species_29364", "species_9024893" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090708": { "compartment": "compartment_12045", "id": "reaction_10090708", "reactome": "R-BTA-9037761", "name": "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024886", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9037755" ], "modifiers": [ [ "species_10090705", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094" ] }, "reaction_10091753": { "compartment": "compartment_70101", "id": "reaction_10091753", "reactome": "R-BTA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10084440" ], "products": [ "species_10085164" ], "modifiers": [], "additional_components": [ "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10084824": { "compartment": "compartment_70101", "id": "reaction_10084824", "reactome": "R-BTA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084753", "species_10075931" ], "products": [ "species_10084779" ], "modifiers": [], "additional_components": [ "A0A3Q1MWJ5", "ENSBTAT00000082605", "ENSBTAT00000028591", "A0A3Q1MWJ5", "ENSBTAT00000082605" ] }, "reaction_10085116": { "compartment": "compartment_876", "id": "reaction_10085116", "reactome": "R-BTA-8866269", "name": "ARRB bind GPCRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10085112" ], "products": [ "species_10085114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10085166": { "compartment": "compartment_876", "id": "reaction_10085166", "reactome": "R-BTA-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085160", "species_10084440" ], "products": [ "species_10085162" ], "modifiers": [ [ "species_10085164", "inhibitor" ] ], "additional_components": [ "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10085134": { "compartment": "compartment_70101", "id": "reaction_10085134", "reactome": "R-BTA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085126", "species_10085130" ], "products": [ "species_10085132" ], "modifiers": [], "additional_components": [ "G5E628", "ENSBTAT00000029117", "ENSBTAT00000084618", "A0A3Q1MSK9", "ENSBTAT00000084618", "G5E628", "ENSBTAT00000029117" ] }, "reaction_10085264": { "compartment": "compartment_876", "id": "reaction_10085264", "reactome": "R-BTA-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085260", "species_10045533" ], "products": [ "species_10085262" ], "modifiers": [], "additional_components": [ "A0A3Q1NKA6", "ENSBTAT00000070874", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1NKA6", "ENSBTAT00000070874" ] }, "reaction_10084819": { "compartment": "compartment_70101", "id": "reaction_10084819", "reactome": "R-BTA-8863721", "name": "NEDD8-STON binds TOR1 hexamer and COP9 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084815", "species_10084779", "species_10084793" ], "products": [ "species_10084817" ], "modifiers": [], "additional_components": [ "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10084757": { "compartment": "compartment_876", "id": "reaction_10084757", "reactome": "R-BTA-8863463", "name": "STON2 binds SYT proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084743", "species_10084753" ], "products": [ "species_10084755" ], "modifiers": [], "additional_components": [ "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553" ] }, "reaction_10084822": { "compartment": "compartment_70101", "id": "reaction_10084822", "reactome": "R-BTA-8863723", "name": "COP9 and TOR1 deneddylate STON2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084817" ], "products": [ "species_10084753", "species_10084815", "species_10075931", "species_10084793" ], "modifiers": [ [ "species_10084817", "catalyst" ] ], "additional_components": [ "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "ENSBTAT00000028591", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10089048": { "compartment": "compartment_70101", "id": "reaction_10089048", "reactome": "R-BTA-8981606", "name": "Myoglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089044", "species_29368" ], "products": [ "species_10089046" ], "modifiers": [], "additional_components": [ "species_71185", "P02192", "ENSBTAT00000084629", "species_113533", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10089058": { "compartment": "compartment_70101", "id": "reaction_10089058", "reactome": "R-BTA-8981610", "name": "Neuroglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_10089054" ], "products": [ "species_10089056" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533" ] }, "reaction_10089060": { "compartment": "compartment_70101", "id": "reaction_10089060", "reactome": "R-BTA-8981621", "name": "Neuroglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089056" ], "products": [ "species_29368", "species_10089054" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533", "species_71185", "Q6WZ19", "ENSBTAT00000021661" ] }, "reaction_10089062": { "compartment": "compartment_70101", "id": "reaction_10089062", "reactome": "R-BTA-8981622", "name": "Myoglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089046" ], "products": [ "species_10089044", "species_29368" ], "modifiers": [], "additional_components": [ "species_113533", "species_71185", "P02192", "ENSBTAT00000084629", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10049869": { "compartment": "compartment_876", "id": "reaction_10049869", "reactome": "R-BTA-446277", "name": "RhCG mediates ammonium efflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049628": { "compartment": "compartment_876", "id": "reaction_10049628", "reactome": "R-BTA-444393", "name": "RhCG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049871": { "compartment": "compartment_876", "id": "reaction_10049871", "reactome": "R-BTA-446278", "name": "RhBG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049635": { "compartment": "compartment_876", "id": "reaction_10049635", "reactome": "R-BTA-444419", "name": "RhBG mediates ammonium effflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049371": { "compartment": "compartment_876", "id": "reaction_10049371", "reactome": "R-BTA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10049368", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068742" ] }, "reaction_10049402": { "compartment": "compartment_876", "id": "reaction_10049402", "reactome": "R-BTA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10049399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072292" ] }, "reaction_10049378": { "compartment": "compartment_876", "id": "reaction_10049378", "reactome": "R-BTA-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10049375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014489" ] }, "reaction_10088912": { "compartment": "compartment_70101", "id": "reaction_10088912", "reactome": "R-BTA-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10088909", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005787" ] }, "reaction_10049358": { "compartment": "compartment_876", "id": "reaction_10049358", "reactome": "R-BTA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10049355", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "ENSBTAT00000074816" ] }, "reaction_10049060": { "compartment": "compartment_876", "id": "reaction_10049060", "reactome": "R-BTA-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_429130" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10049057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061504" ] }, "reaction_10049078": { "compartment": "compartment_876", "id": "reaction_10049078", "reactome": "R-BTA-429571", "name": "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429652", "species_74113" ], "products": [ "species_83910", "species_429648" ], "modifiers": [ [ "species_10049075", "catalyst" ] ], "additional_components": [ "CHEBI:27372", "species_426910", "species_426910", "CHEBI:27372", "ENSBTAT00000004510" ] }, "reaction_10049592": { "compartment": "compartment_876", "id": "reaction_10049592", "reactome": "R-BTA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10049589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035184" ] }, "reaction_10049613": { "compartment": "compartment_876", "id": "reaction_10049613", "reactome": "R-BTA-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10049610", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_209914", "species_390899", "species_209789", "species_209789", "CHEBI:28918", "species_390899", "species_159362", "species_209914", "ENSBTAT00000045811" ] }, "reaction_10049599": { "compartment": "compartment_876", "id": "reaction_10049599", "reactome": "R-BTA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10049596", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087022" ] }, "reaction_10049319": { "compartment": "compartment_876", "id": "reaction_10049319", "reactome": "R-BTA-433089", "name": "SOAT can transport taurolithocholate-3-sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433120", "species_74113" ], "products": [ "species_83910", "species_176483" ], "modifiers": [ [ "species_10049316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066284" ] }, "reaction_10049606": { "compartment": "compartment_876", "id": "reaction_10049606", "reactome": "R-BTA-444126", "name": "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10049603", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002712" ] }, "reaction_10049080": { "compartment": "compartment_876", "id": "reaction_10049080", "reactome": "R-BTA-429581", "name": "SLC5A6 transports vitamins from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429605", "species_74113" ], "products": [ "species_429627", "species_83910" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "CHEBI:16494", "species_199207", "species_196820", "species_199207", "species_196820", "CHEBI:16494", "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10051577": { "compartment": "compartment_20699", "id": "reaction_10051577", "reactome": "R-BTA-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051580": { "compartment": "compartment_20699", "id": "reaction_10051580", "reactome": "R-BTA-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051587": { "compartment": "compartment_20699", "id": "reaction_10051587", "reactome": "R-BTA-744230", "name": "SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_744239" ], "products": [ "species_113578", "species_744233" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026562" ] }, "reaction_10039874": { "compartment": "compartment_12045", "id": "reaction_10039874", "reactome": "R-BTA-174368", "name": "SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_162756" ], "products": [ "species_3499326", "species_174384" ], "modifiers": [ [ "species_10039871", "catalyst" ] ], "additional_components": [ "A2VE55", "ENSBTAT00000026562" ] }, "reaction_10051899": { "compartment": "compartment_876", "id": "reaction_10051899", "reactome": "R-BTA-879594", "name": "SLCO4C1 mediates the transport of digoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879521" ], "products": [ "species_879517" ], "modifiers": [ [ "species_10051896", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021761" ] }, "reaction_10051866": { "compartment": "compartment_876", "id": "reaction_10051866", "reactome": "R-BTA-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051863", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "E1BC23", "ENSBTAT00000026117", "E1BPV8", "ENSBTAT00000021795", "F1MM56", "ENSBTAT00000003345", "F1MYV0", "ENSBTAT00000030217" ] }, "reaction_10051843": { "compartment": "compartment_876", "id": "reaction_10051843", "reactome": "R-BTA-879528", "name": "SLCO2A1 transports PGT substrates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879566" ], "products": [ "species_879614" ], "modifiers": [ [ "species_10051840", "catalyst" ] ], "additional_components": [ "species_879535", "CHEBI:15544", "species_416911", "species_391930", "species_416911", "CHEBI:15544", "species_879535", "species_391930", "ENSBTAT00000001747" ] }, "reaction_10091250": { "compartment": "compartment_876", "id": "reaction_10091250", "reactome": "R-BTA-9631987", "name": "SLCO1B1 transports T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "ENSBTAT00000030217" ] }, "reaction_10051879": { "compartment": "compartment_876", "id": "reaction_10051879", "reactome": "R-BTA-879584", "name": "SLCO3A1 isoform 1 has abroad substrate specificity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051868" ], "products": [ "species_10051872" ], "modifiers": [ [ "species_10051876", "catalyst" ] ], "additional_components": [ "species_352326", "CHEBI:15544", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "CHEBI:15544", "species_352326", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "ENSBTAT00000055950" ] }, "reaction_10070928": { "compartment": "compartment_984", "id": "reaction_10070928", "reactome": "R-BTA-5229283", "name": "LCNs bind lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070924", "species_5229279" ], "products": [ "species_10070926" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576", "species_5229279", "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576" ] }, "reaction_10051892": { "compartment": "compartment_876", "id": "reaction_10051892", "reactome": "R-BTA-879585", "name": "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879559" ], "products": [ "species_879544" ], "modifiers": [ [ "species_10051889", "catalyst" ] ], "additional_components": [ "CHEBI:16196", "CHEBI:16196", "Q0VCQ2", "ENSBTAT00000020526", "A6QQD5", "ENSBTAT00000044112" ] }, "reaction_10036297": { "compartment": "compartment_70101", "id": "reaction_10036297", "reactome": "R-BTA-109539", "name": "Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179740", "species_74113" ], "products": [ "species_179741", "species_83910" ], "modifiers": [ [ "species_10036294", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83909", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "ENSBTAT00000021720" ] }, "reaction_10051545": { "compartment": "compartment_70101", "id": "reaction_10051545", "reactome": "R-BTA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "ENSBTAT00000010219" ] }, "reaction_10071001": { "compartment": "compartment_5460", "id": "reaction_10071001", "reactome": "R-BTA-5250210", "name": "ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070999" ], "products": [ "species_10070983" ], "modifiers": [], "additional_components": [ "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036283": { "compartment": "compartment_70101", "id": "reaction_10036283", "reactome": "R-BTA-109530", "name": "Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179738", "species_74113" ], "products": [ "species_179739", "species_83910" ], "modifiers": [ [ "species_10036280", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "CHEBI:17256", "CHEBI:17256", "species_83909", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000075356" ] }, "reaction_10051547": { "compartment": "compartment_70101", "id": "reaction_10051547", "reactome": "R-BTA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "ENSBTAT00000010219" ] }, "reaction_10071003": { "compartment": "compartment_70101", "id": "reaction_10071003", "reactome": "R-BTA-5250217", "name": "ARL2:GTP binds ARL2BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070997", "species_10070995" ], "products": [ "species_10070999" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006363", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10070991": { "compartment": "compartment_5460", "id": "reaction_10070991", "reactome": "R-BTA-5250209", "name": "ARL2:GTP:ARL2BP binds SLC25A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070983", "species_10070987" ], "products": [ "species_10070989" ], "modifiers": [], "additional_components": [ "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363", "ENSBTAT00000017580", "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10073838": { "compartment": "compartment_70616", "id": "reaction_10073838", "reactome": "R-BTA-5672027", "name": "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10070989", "catalyst" ] ], "additional_components": [ "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036290": { "compartment": "compartment_70101", "id": "reaction_10036290", "reactome": "R-BTA-109538", "name": "Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737", "species_74113" ], "products": [ "species_179743", "species_83910" ], "modifiers": [ [ "species_10036287", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000024328" ] }, "reaction_10036274": { "compartment": "compartment_70101", "id": "reaction_10036274", "reactome": "R-BTA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "ENSBTAT00000015948" ] }, "reaction_10036276": { "compartment": "compartment_70101", "id": "reaction_10036276", "reactome": "R-BTA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "ENSBTAT00000015948" ] }, "reaction_10038660": { "compartment": "compartment_70616", "id": "reaction_10038660", "reactome": "R-BTA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10038657", "catalyst" ] ], "additional_components": [ "P32007", "ENSBTAT00000063682" ] }, "reaction_10048747": { "compartment": "compartment_876", "id": "reaction_10048747", "reactome": "R-BTA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010384" ] }, "reaction_10085896": { "compartment": "compartment_70101", "id": "reaction_10085896", "reactome": "R-BTA-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_113529", "species_113552" ], "modifiers": [ [ "species_10085893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001624" ] }, "reaction_10049083": { "compartment": "compartment_876", "id": "reaction_10049083", "reactome": "R-BTA-429591", "name": "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10060218": { "compartment": "compartment_70616", "id": "reaction_10060218", "reactome": "R-BTA-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198498", "species_1614584" ], "products": [ "species_113544", "species_174375" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10048821": { "compartment": "compartment_201753", "id": "reaction_10048821", "reactome": "R-BTA-428052", "name": "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_428548" ], "products": [ "species_70106", "species_428614" ], "modifiers": [ [ "species_10048818", "catalyst" ] ], "additional_components": [ "A4FV52", "ENSBTAT00000009255", "A6QLI1", "ENSBTAT00000007935", "E1BA07", "ENSBTAT00000001445" ] }, "reaction_10049173": { "compartment": "compartment_876", "id": "reaction_10049173", "reactome": "R-BTA-429767", "name": "Passive I- efflux mediated by SMCT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015315" ] }, "reaction_10048601": { "compartment": "compartment_876", "id": "reaction_10048601", "reactome": "R-BTA-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_74113" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10048598", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076302" ] }, "reaction_10048618": { "compartment": "compartment_876", "id": "reaction_10048618", "reactome": "R-BTA-426155", "name": "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_352022" ], "products": [ "species_74126", "species_188972" ], "modifiers": [ [ "species_10048615", "catalyst" ] ], "additional_components": [ "E1BCI8", "ENSBTAT00000024019", "A0A3S5ZPL9", "ENSBTAT00000018852", "A0A3Q1NIV4", "ENSBTAT00000082311" ] }, "reaction_10048594": { "compartment": "compartment_876", "id": "reaction_10048594", "reactome": "R-BTA-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_188972", "species_74113" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10048591", "catalyst" ] ], "additional_components": [ "ENSBTAT00000046583" ] }, "reaction_10048795": { "compartment": "compartment_876", "id": "reaction_10048795", "reactome": "R-BTA-427998", "name": "Proton-coupled di- and tri-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428037" ], "products": [ "species_428026", "species_70106" ], "modifiers": [ [ "species_10048792", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:47923", "CHEBI:47923", "CHEBI:90799", "ENSBTAT00000001891" ] }, "reaction_10048802": { "compartment": "compartment_17938", "id": "reaction_10048802", "reactome": "R-BTA-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_427984" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10048799", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:90799", "CHEBI:46761", "species_29612", "ENSBTAT00000030236" ] }, "reaction_10048965": { "compartment": "compartment_201753", "id": "reaction_10048965", "reactome": "R-BTA-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428592", "species_428548" ], "products": [ "species_428632", "species_70106" ], "modifiers": [ [ "species_10048962", "catalyst" ] ], "additional_components": [ "species_29424", "species_428571", "species_428571", "species_29424", "ENSBTAT00000063578" ] }, "reaction_10048804": { "compartment": "compartment_876", "id": "reaction_10048804", "reactome": "R-BTA-428015", "name": "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428027", "species_29804", "species_74113" ], "products": [ "species_74126", "species_427997", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ] ], "additional_components": [ "species_427963", "CHEBI:17364", "species_210382", "species_427963", "CHEBI:17364", "species_210382", "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455" ] }, "reaction_10048491": { "compartment": "compartment_876", "id": "reaction_10048491", "reactome": "R-BTA-425483", "name": "SLC4A5,7,9 cotransport Na+ with 3HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_83910" ], "products": [ "species_425425", "species_74113" ], "modifiers": [ [ "species_10048488", "catalyst" ] ], "additional_components": [ "E1BBH7", "ENSBTAT00000006425", "E1BIN2", "ENSBTAT00000029024" ] }, "reaction_10048478": { "compartment": "compartment_876", "id": "reaction_10048478", "reactome": "R-BTA-425482", "name": "SLC4A1,2,3 exchanges HCO3- for Cl-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048475", "catalyst" ] ], "additional_components": [ "E1BKK3", "ENSBTAT00000019936", "A0A3Q1M051", "ENSBTAT00000071207" ] }, "reaction_10049053": { "compartment": "compartment_876", "id": "reaction_10049053", "reactome": "R-BTA-429094", "name": "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10049050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066412" ] }, "reaction_10089038": { "compartment": "compartment_70101", "id": "reaction_10089038", "reactome": "R-BTA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089035", "catalyst" ] ], "additional_components": [ "Q27994", "ENSBTAT00000012109" ] }, "reaction_10089024": { "compartment": "compartment_70101", "id": "reaction_10089024", "reactome": "R-BTA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089021", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889", "A0A3Q1MA30", "ENSBTAT00000042945" ] }, "reaction_10085907": { "compartment": "compartment_70101", "id": "reaction_10085907", "reactome": "R-BTA-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10085904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010116" ] }, "reaction_10089029": { "compartment": "compartment_70101", "id": "reaction_10089029", "reactome": "R-BTA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089026", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10049046": { "compartment": "compartment_876", "id": "reaction_10049046", "reactome": "R-BTA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10049043", "catalyst" ] ], "additional_components": [ "species_70113", "species_30034", "species_29532", "species_70113", "species_30034", "species_29532", "ENSBTAT00000079223" ] }, "reaction_10037913": { "compartment": "compartment_984", "id": "reaction_10037913", "reactome": "R-BTA-140777", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037910", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037899": { "compartment": "compartment_876", "id": "reaction_10037899", "reactome": "R-BTA-140761", "name": "sequestered tissue factor -> tissue factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037897" ], "products": [ "species_10037864" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009341", "ENSBTAT00000009341" ] }, "reaction_10037915": { "compartment": "compartment_984", "id": "reaction_10037915", "reactome": "R-BTA-140783", "name": "tissue factor (TF) + factor VII (F7) -> TF:F7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903", "species_10037864" ], "products": [ "species_10037910" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037887": { "compartment": "compartment_984", "id": "reaction_10037887", "reactome": "R-BTA-140736", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857", "species_74112" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037884", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10037937": { "compartment": "compartment_984", "id": "reaction_10037937", "reactome": "R-BTA-140825", "name": "TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037807", "species_10037884", "species_10037931" ], "products": [ "species_10037935" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016", "ENSBTAT00000085417", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "A0A3Q1NLA0", "ENSBTAT00000085417", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037906": { "compartment": "compartment_984", "id": "reaction_10037906", "reactome": "R-BTA-140769", "name": "factor VII -> factor VIIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903" ], "products": [ "species_10037893" ], "modifiers": [ [ "species_10037807", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037895": { "compartment": "compartment_984", "id": "reaction_10037895", "reactome": "R-BTA-140748", "name": "tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037893", "species_10037864" ], "products": [ "species_10037884" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10048635": { "compartment": "compartment_876", "id": "reaction_10048635", "reactome": "R-BTA-426223", "name": "Cation influx mediated by TRPC3/6/7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426219" ], "products": [ "species_426221" ], "modifiers": [ [ "species_10048630", "catalyst" ] ], "additional_components": [ "species_83910", "species_74016", "species_29926", "species_74016", "species_29926", "species_83910", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10037607": { "compartment": "compartment_876", "id": "reaction_10037607", "reactome": "R-BTA-139855", "name": "P2X1-mediated entry of Ca++ from plasma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10037604", "catalyst" ] ], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10044680": { "compartment": "compartment_7660", "id": "reaction_10044680", "reactome": "R-BTA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044676", "species_29428" ], "products": [ "species_10044678" ], "modifiers": [], "additional_components": [ "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096", "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096" ] }, "reaction_10044142": { "compartment": "compartment_13231", "id": "reaction_10044142", "reactome": "R-BTA-211206", "name": "Translocation of DFF to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044132" ], "products": [ "species_10044140" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044144": { "compartment": "compartment_7660", "id": "reaction_10044144", "reactome": "R-BTA-211207", "name": "Cleaved fragments of DFF45 dissociate from DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044108" ], "products": [ "species_10044098", "species_10044094", "species_10044106", "species_10044104" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000017999" ] }, "reaction_10044146": { "compartment": "compartment_70101", "id": "reaction_10044146", "reactome": "R-BTA-211224", "name": "Association of DFF40 with DFF45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044118", "species_10044120" ], "products": [ "species_10044122" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "ENSBTAT00000017999", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044116": { "compartment": "compartment_7660", "id": "reaction_10044116", "reactome": "R-BTA-211193", "name": "Homodimerization of DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044094" ], "products": [ "species_10044114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10066489": { "compartment": "compartment_70101", "id": "reaction_10066489", "reactome": "R-BTA-3000339", "name": "Phosphorylated BORA binds SCF-beta-TrCp1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10066480" ], "products": [ "species_10066482" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "ENSBTAT00000026496", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10065938": { "compartment": "compartment_70101", "id": "reaction_10065938", "reactome": "R-BTA-2562594", "name": "Phosphorylated OPTN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065934" ], "products": [ "species_10065936" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021808", "ENSBTAT00000021808" ] }, "reaction_10066487": { "compartment": "compartment_70101", "id": "reaction_10066487", "reactome": "R-BTA-3000335", "name": "SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066482", "species_10033408" ], "products": [ "species_10066484", "species_10056243" ], "modifiers": [ [ "species_10066482", "catalyst" ] ], "additional_components": [ "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3C9", "ENSBTAT00000026496", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10084216": { "compartment": "compartment_70101", "id": "reaction_10084216", "reactome": "R-BTA-8854052", "name": "Formation of the SCF-FBXL7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10039822", "species_10043871", "species_10039818" ], "products": [ "species_10084098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004177", "ENSBTAT00000068449", "ENSBTAT00000075328", "ENSBTAT00000035306", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177" ] }, "reaction_10084206": { "compartment": "compartment_70101", "id": "reaction_10084206", "reactome": "R-BTA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084100", "species_10033408" ], "products": [ "species_10084203" ], "modifiers": [ [ "species_10084100", "catalyst" ] ], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA06", "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084102": { "compartment": "compartment_70101", "id": "reaction_10084102", "reactome": "R-BTA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084098" ], "products": [ "species_10084100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084214": { "compartment": "compartment_70101", "id": "reaction_10084214", "reactome": "R-BTA-8854051", "name": "SCF-FBXL18 ubiquitinates FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10033408" ], "products": [ "species_10084209" ], "modifiers": [ [ "species_10084211", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004177", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F6PQR5", "ENSBTAT00000046646" ] }, "reaction_10039612": { "compartment": "compartment_13231", "id": "reaction_10039612", "reactome": "R-BTA-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039608" ], "products": [ "species_10039610" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10039614": { "compartment": "compartment_13231", "id": "reaction_10039614", "reactome": "R-BTA-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039610" ], "products": [ "species_10039608" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10084043": { "compartment": "compartment_70101", "id": "reaction_10084043", "reactome": "R-BTA-8852331", "name": "GTSE1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084039" ], "products": [ "species_10084041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009339", "ENSBTAT00000009339" ] }, "reaction_10084028": { "compartment": "compartment_70101", "id": "reaction_10084028", "reactome": "R-BTA-8852280", "name": "GTSE1 binds microtubule lattice in interphase cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10084024" ], "products": [ "species_10084026" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "species_29438", "species_29420" ] }, "reaction_10084047": { "compartment": "compartment_7660", "id": "reaction_10084047", "reactome": "R-BTA-8852337", "name": "GTSE1 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675", "species_10084041" ], "products": [ "species_10084045" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10084051": { "compartment": "compartment_70101", "id": "reaction_10084051", "reactome": "R-BTA-8852351", "name": "GTSE1 promotes translocation of TP53 to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084045" ], "products": [ "species_10084049" ], "modifiers": [], "additional_components": [ "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10087635": { "compartment": "compartment_70616", "id": "reaction_10087635", "reactome": "R-BTA-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039037" ], "products": [ "species_10087633" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326" ] }, "reaction_10052963": { "compartment": "compartment_70101", "id": "reaction_10052963", "reactome": "R-BTA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052929", "species_10052959" ], "products": [ "species_10052961" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027868", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10083789": { "compartment": "compartment_876", "id": "reaction_10083789", "reactome": "R-BTA-8849891", "name": "SALMs 1-3 bind to PSD-95 family members", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083783", "species_10083785" ], "products": [ "species_10083787" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778" ] }, "reaction_10083793": { "compartment": "compartment_876", "id": "reaction_10083793", "reactome": "R-BTA-8849900", "name": "SALMs1-3 bind each other in cis interactions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083785" ], "products": [ "species_10083791" ], "modifiers": [], "additional_components": [ "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10084356": { "compartment": "compartment_876", "id": "reaction_10084356", "reactome": "R-BTA-8855648", "name": "SALM3 binds LAR-RPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083779", "species_10046864" ], "products": [ "species_10084354" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053062", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10087862": { "compartment": "compartment_7660", "id": "reaction_10087862", "reactome": "R-BTA-8951676", "name": "RUNX3 binds TEADs and YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087858", "species_10084943" ], "products": [ "species_10087860" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10087997": { "compartment": "compartment_7660", "id": "reaction_10087997", "reactome": "R-BTA-8952058", "name": "CCND1 binds RUNX3 and displaces EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087908", "species_10056568" ], "products": [ "species_10053052", "species_10087995" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "ENSBTAT00000023277", "ENSBTAT00000021556", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087900": { "compartment": "compartment_7660", "id": "reaction_10087900", "reactome": "R-BTA-8951966", "name": "EP300 acetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10087887" ], "products": [ "species_2485002", "species_10087897" ], "modifiers": [ [ "species_10087887", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087889": { "compartment": "compartment_7660", "id": "reaction_10087889", "reactome": "R-BTA-8951951", "name": "RUNX3 binds EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084945", "species_10053052" ], "products": [ "species_10087887" ], "modifiers": [], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087910": { "compartment": "compartment_7660", "id": "reaction_10087910", "reactome": "R-BTA-8951977", "name": "Acetylated RUNX3 binds to BRD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087906", "species_10087897" ], "products": [ "species_10087908" ], "modifiers": [], "additional_components": [ "Q32S26", "ENSBTAT00000014704", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704" ] }, "reaction_10088006": { "compartment": "compartment_7660", "id": "reaction_10088006", "reactome": "R-BTA-8952069", "name": "HDAC4 deacetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10088001" ], "products": [ "species_10087906", "species_10088003", "species_427486" ], "modifiers": [ [ "species_10088001", "catalyst" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "A0A452DIV3", "ENSBTAT00000023277", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088012": { "compartment": "compartment_7660", "id": "reaction_10088012", "reactome": "R-BTA-8952128", "name": "RUNX3 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066677", "species_10084943" ], "products": [ "species_10088010" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "P67939", "ENSBTAT00000001420" ] }, "reaction_10086231": { "compartment": "compartment_7660", "id": "reaction_10086231", "reactome": "R-BTA-8878117", "name": "RUNX3 binds ZFHX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086227", "species_10084943" ], "products": [ "species_10086229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019489", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BPV9", "ENSBTAT00000019489" ] }, "reaction_10086587": { "compartment": "compartment_70101", "id": "reaction_10086587", "reactome": "R-BTA-8937807", "name": "SRC phosphorylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086579", "species_113592" ], "products": [ "species_29370", "species_10057248", "species_10086584" ], "modifiers": [ [ "species_10086579", "catalyst" ] ], "additional_components": [ "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088490": { "compartment": "compartment_7660", "id": "reaction_10088490", "reactome": "R-BTA-8952419", "name": "SMURFs ubiquitinate RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10036828" ], "products": [ "species_10088485" ], "modifiers": [ [ "species_10088487", "catalyst" ], [ "species_10053052", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000070567", "ENSBTAT00000043725", "ENSBTAT00000021556" ] }, "reaction_10086589": { "compartment": "compartment_70101", "id": "reaction_10086589", "reactome": "R-BTA-8937814", "name": "RUNX3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086577" ], "products": [ "species_10084943" ], "modifiers": [ [ "species_10057248", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567", "ENSBTAT00000011767" ] }, "reaction_10084947": { "compartment": "compartment_7660", "id": "reaction_10084947", "reactome": "R-BTA-8865454", "name": "CBFB binds RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10084939" ], "products": [ "species_10084945" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000021434", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088482": { "compartment": "compartment_7660", "id": "reaction_10088482", "reactome": "R-BTA-8952399", "name": "Polyubiquitinated RUNX3 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088478" ], "products": [ "species_10088480" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567" ] }, "reaction_10086581": { "compartment": "compartment_70101", "id": "reaction_10086581", "reactome": "R-BTA-8937792", "name": "RUNX3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10086577" ], "products": [ "species_10086579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040059": { "compartment": "compartment_7660", "id": "reaction_10040059", "reactome": "R-BTA-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040054", "species_10040050" ], "products": [ "species_10040056" ], "modifiers": [ [ "species_10040054", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525" ] }, "reaction_10040955": { "compartment": "compartment_70101", "id": "reaction_10040955", "reactome": "R-BTA-191636", "name": "Phosphorylation of Cx43 by c-src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040945" ], "products": [ "species_29370", "species_10040952" ], "modifiers": [ [ "species_10040945", "catalyst" ] ], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040961": { "compartment": "compartment_70101", "id": "reaction_10040961", "reactome": "R-BTA-191654", "name": "c-src associates with Cx43 in gap junctions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040959", "species_10040957" ], "products": [ "species_10040945" ], "modifiers": [], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040967": { "compartment": "compartment_876", "id": "reaction_10040967", "reactome": "R-BTA-191656", "name": "Closure of gap junction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040965" ], "products": [ "species_10040965" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398" ] }, "reaction_10085313": { "compartment": "compartment_876", "id": "reaction_10085313", "reactome": "R-BTA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060424", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076329" ] }, "reaction_10083179": { "compartment": "compartment_263163", "id": "reaction_10083179", "reactome": "R-BTA-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083175", "species_10083141" ], "products": [ "species_10083177" ], "modifiers": [], "additional_components": [ "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850" ] }, "reaction_10083149": { "compartment": "compartment_263163", "id": "reaction_10083149", "reactome": "R-BTA-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083119", "species_10083147" ], "products": [ "species_10083128" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438" ] }, "reaction_10083340": { "compartment": "compartment_432051", "id": "reaction_10083340", "reactome": "R-BTA-6814670", "name": "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083331" ], "products": [ "species_10083335", "species_10083333", "species_10083337" ], "modifiers": [ [ "species_10083331", "catalyst" ] ], "additional_components": [ "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "Q5EA50", "ENSBTAT00000074576", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "ENSBTAT00000015669", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083342": { "compartment": "compartment_263163", "id": "reaction_10083342", "reactome": "R-BTA-6814675", "name": "RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083329", "species_10083323" ], "products": [ "species_10083331" ], "modifiers": [], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083187": { "compartment": "compartment_70101", "id": "reaction_10083187", "reactome": "R-BTA-6814096", "name": "ARL1:GTP binds SCOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083183", "species_10083135" ], "products": [ "species_10083185" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065986", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "A0A3Q1M9K7", "ENSBTAT00000065986" ] }, "reaction_10083143": { "compartment": "compartment_263163", "id": "reaction_10083143", "reactome": "R-BTA-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083135", "species_10083128" ], "products": [ "species_10083141" ], "modifiers": [], "additional_components": [ "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767" ] }, "reaction_10083451": { "compartment": "compartment_20699", "id": "reaction_10083451", "reactome": "R-BTA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083439" ], "products": [ "species_10083449" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083425": { "compartment": "compartment_20699", "id": "reaction_10083425", "reactome": "R-BTA-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083421" ], "products": [ "species_10083423" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1MQ84", "ENSBTAT00000084706", "A0A3Q1MQ84", "ENSBTAT00000084706", "species_29438", "P84080", "ENSBTAT00000010159" ] }, "reaction_10083056": { "compartment": "compartment_20699", "id": "reaction_10083056", "reactome": "R-BTA-6811433", "name": "The COG tethering complex interacts with numerous SNAREs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083052" ], "products": [ "species_10083054" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10083458": { "compartment": "compartment_20699", "id": "reaction_10083458", "reactome": "R-BTA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083449" ], "products": [ "species_10083455" ], "modifiers": [ [ "species_10083449", "catalyst" ] ], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "P84080", "ENSBTAT00000010159", "species_29420", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083767": { "compartment": "compartment_20699", "id": "reaction_10083767", "reactome": "R-BTA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083763" ], "products": [ "species_10083765" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10065827": { "compartment": "compartment_876", "id": "reaction_10065827", "reactome": "R-BTA-2534346", "name": "SPAM1 Binds Hyaluronic Acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065823", "species_1297302" ], "products": [ "species_10065825" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045309", "species_1297302", "F1MZM9", "ENSBTAT00000045309" ] }, "reaction_10047292": { "compartment": "compartment_984", "id": "reaction_10047292", "reactome": "R-BTA-391155", "name": "SIRPA binds SFTPA oligomer, SFTPD oligomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047270", "species_10047288" ], "products": [ "species_10047290" ], "modifiers": [], "additional_components": [ "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380" ] }, "reaction_10060207": { "compartment": "compartment_70101", "id": "reaction_10060207", "reactome": "R-BTA-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_174369" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10060204", "catalyst" ] ], "additional_components": [ "species_71185", "F1MEW4", "ENSBTAT00000087445" ] }, "reaction_10060231": { "compartment": "compartment_70101", "id": "reaction_10060231", "reactome": "R-BTA-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_111707", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060275": { "compartment": "compartment_70101", "id": "reaction_10060275", "reactome": "R-BTA-1614654", "name": "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352015", "species_174369" ], "products": [ "species_174390", "species_1614585" ], "modifiers": [ [ "species_10060272", "catalyst" ] ], "additional_components": [ "species_29426", "A0A452DHV7", "ENSBTAT00000002916" ] }, "reaction_10057032": { "compartment": "compartment_70101", "id": "reaction_10057032", "reactome": "R-BTA-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_353106" ], "products": [ "species_1237165", "species_83951" ], "modifiers": [ [ "species_10057029", "catalyst" ] ], "additional_components": [ "Q3MHF7", "ENSBTAT00000048509" ] }, "reaction_10057023": { "compartment": "compartment_70101", "id": "reaction_10057023", "reactome": "R-BTA-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1237176" ], "products": [ "species_29372", "species_70106", "species_1237155" ], "modifiers": [ [ "species_10057020", "catalyst" ] ], "additional_components": [ "Q0VD27", "ENSBTAT00000019702", "species_29926" ] }, "reaction_10057684": { "compartment": "compartment_70101", "id": "reaction_10057684", "reactome": "R-BTA-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10057011", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003273" ] }, "reaction_10090681": { "compartment": "compartment_5460", "id": "reaction_10090681", "reactome": "R-BTA-9035484", "name": "CysS248-MPST:TXN2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090677" ], "products": [ "species_10089847", "species_10067705", "species_1655881" ], "modifiers": [], "additional_components": [ "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014", "ENSBTAT00000069079", "ENSBTAT00000000014" ] }, "reaction_10089850": { "compartment": "compartment_5460", "id": "reaction_10089850", "reactome": "R-BTA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090013": { "compartment": "compartment_5460", "id": "reaction_10090013", "reactome": "R-BTA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10060252": { "compartment": "compartment_70101", "id": "reaction_10060252", "reactome": "R-BTA-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111707" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060255": { "compartment": "compartment_70101", "id": "reaction_10060255", "reactome": "R-BTA-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_174369" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090015": { "compartment": "compartment_5460", "id": "reaction_10090015", "reactome": "R-BTA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090679": { "compartment": "compartment_5460", "id": "reaction_10090679", "reactome": "R-BTA-9035227", "name": "TXN2 binds CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_10090669" ], "products": [ "species_10090677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000069079", "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014" ] }, "reaction_10060361": { "compartment": "compartment_5460", "id": "reaction_10060361", "reactome": "R-BTA-1655879", "name": "Thiosulfate can transfer its sulfur atom to glutathione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_113529", "species_1655887" ], "products": [ "species_1655882", "species_1614538", "species_1655881" ], "modifiers": [ [ "species_10060358", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023735" ] }, "reaction_10060216": { "compartment": "compartment_5460", "id": "reaction_10060216", "reactome": "R-BTA-1614544", "name": "Sulfite is oxidized to sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_1614538", "species_113521" ], "products": [ "species_1614617", "species_1614584" ], "modifiers": [ [ "species_10060213", "catalyst" ] ], "additional_components": [ "Q3MHX0", "ENSBTAT00000008101", "species_947539" ] }, "reaction_10060250": { "compartment": "compartment_70616", "id": "reaction_10060250", "reactome": "R-BTA-1614605", "name": "Persulfide sulfur is dioxygenated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10060239", "species_113521" ], "products": [ "species_10060241", "species_113529", "species_1614538" ], "modifiers": [ [ "species_10060247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013690", "ENSBTAT00000013690", "Q3T094", "ENSBTAT00000005747", "species_29426" ] }, "reaction_10060264": { "compartment": "compartment_70101", "id": "reaction_10060264", "reactome": "R-BTA-1614645", "name": "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29368" ], "products": [ "species_1614519" ], "modifiers": [ [ "species_10060261", "catalyst" ] ], "additional_components": [ "A0A3Q1MCZ5", "ENSBTAT00000079843", "species_71067" ] }, "reaction_10060234": { "compartment": "compartment_70101", "id": "reaction_10060234", "reactome": "R-BTA-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614582", "species_1614532" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090671": { "compartment": "compartment_5460", "id": "reaction_10090671", "reactome": "R-BTA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089847", "species_9012592" ], "products": [ "species_113557", "species_10090669" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079", "ENSBTAT00000069079", "ENSBTAT00000069079" ] }, "reaction_10083204": { "compartment": "compartment_70101", "id": "reaction_10083204", "reactome": "R-BTA-6814153", "name": "ADO oxidises 2AET to HTAU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_6814151" ], "products": [ "species_1655445", "species_70106" ], "modifiers": [ [ "species_10083201", "catalyst" ] ], "additional_components": [ "G3MZK0", "ENSBTAT00000064438", "species_71067" ] }, "reaction_10060228": { "compartment": "compartment_70101", "id": "reaction_10060228", "reactome": "R-BTA-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10089959": { "compartment": "compartment_5460", "id": "reaction_10089959", "reactome": "R-BTA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10089956", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043317" ] }, "reaction_10077124": { "compartment": "compartment_70101", "id": "reaction_10077124", "reactome": "R-BTA-5696838", "name": "BHMT2 tetramer transfers CH3 group from SMM to LHCYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4789070", "species_174369" ], "products": [ "species_70106", "species_174390" ], "modifiers": [ [ "species_10077121", "catalyst" ] ], "additional_components": [ "species_29426", "F1N4C6", "ENSBTAT00000048928" ] }, "reaction_10078575": { "compartment": "compartment_5460", "id": "reaction_10078575", "reactome": "R-BTA-6797913", "name": "SARDH:FAD oxidatively demethylates SARC to Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6797917", "species_113521" ], "products": [ "species_159549", "species_6797920" ], "modifiers": [ [ "species_10078572", "catalyst" ] ], "additional_components": [ "A0A3Q1MR10", "ENSBTAT00000075705", "species_113596" ] }, "reaction_10078582": { "compartment": "compartment_5460", "id": "reaction_10078582", "reactome": "R-BTA-6797961", "name": "CHDH oxidises Cho to BETALD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_6798162" ], "products": [ "species_6798194", "species_31649" ], "modifiers": [ [ "species_10078579", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013227" ] }, "reaction_10044844": { "compartment": "compartment_70101", "id": "reaction_10044844", "reactome": "R-BTA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10044841", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006978" ] }, "reaction_10044851": { "compartment": "compartment_70101", "id": "reaction_10044851", "reactome": "R-BTA-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10044848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054971" ] }, "reaction_10033778": { "compartment": "compartment_70101", "id": "reaction_10033778", "reactome": "R-BTA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10033775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005575" ] }, "reaction_10033788": { "compartment": "compartment_70101", "id": "reaction_10033788", "reactome": "R-BTA-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_508182" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10033785", "catalyst" ] ], "additional_components": [ "CHEBI:57427", "CHEBI:58045", "species_29702", "CHEBI:28654", "CHEBI:17865", "CHEBI:16530", "A0A3Q1ML78", "ENSBTAT00000086973" ] }, "reaction_10033806": { "compartment": "compartment_5460", "id": "reaction_10033806", "reactome": "R-BTA-70785", "name": "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70772", "species_113521" ], "products": [ "species_70784" ], "modifiers": [ [ "species_10033803", "catalyst" ] ], "additional_components": [ "A0A3Q1M9N4", "ENSBTAT00000068139" ] }, "reaction_10051185": { "compartment": "compartment_5460", "id": "reaction_10051185", "reactome": "R-BTA-508369", "name": "alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_70836", "species_29362" ], "products": [ "species_70829", "species_113526" ], "modifiers": [ [ "species_10033812", "catalyst" ] ], "additional_components": [ "O02691", "ENSBTAT00000023642" ] }, "reaction_10033824": { "compartment": "compartment_5460", "id": "reaction_10033824", "reactome": "R-BTA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10033797": { "compartment": "compartment_5460", "id": "reaction_10033797", "reactome": "R-BTA-70745", "name": "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_70715" ], "products": [ "species_70744", "species_31649" ], "modifiers": [ [ "species_10033794", "catalyst" ] ], "additional_components": [ "A0A452DI40", "ENSBTAT00000005782", "species_113596" ] }, "reaction_10052027": { "compartment": "compartment_70101", "id": "reaction_10052027", "reactome": "R-BTA-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10052024", "catalyst" ] ], "additional_components": [ "species_71185", "E1BPE1", "ENSBTAT00000007525" ] }, "reaction_10052043": { "compartment": "compartment_70101", "id": "reaction_10052043", "reactome": "R-BTA-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_29432", "species_893615" ], "modifiers": [ [ "species_10052037", "catalyst" ], [ "species_29502", "inhibitor" ], [ "species_8939576", "inhibitor" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10033979": { "compartment": "compartment_70101", "id": "reaction_10033979", "reactome": "R-BTA-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34351", "species_29356" ], "products": [ "species_29432", "species_30487" ], "modifiers": [ [ "species_10033976", "catalyst" ] ], "additional_components": [ "A0A3Q1MB81", "ENSBTAT00000069075" ] }, "reaction_10052030": { "compartment": "compartment_5460", "id": "reaction_10052030", "reactome": "R-BTA-893583", "name": "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_893607" ], "products": [ "species_893617", "species_113552" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10033969": { "compartment": "compartment_70101", "id": "reaction_10033969", "reactome": "R-BTA-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_29970" ], "products": [ "species_34351", "species_29356", "species_29366" ], "modifiers": [ [ "species_10033966", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073847" ] }, "reaction_10085381": { "compartment": "compartment_876", "id": "reaction_10085381", "reactome": "R-BTA-8870352", "name": "SLC36A4 transports L-Trp from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352006" ], "products": [ "species_29500" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10033988": { "compartment": "compartment_70101", "id": "reaction_10033988", "reactome": "R-BTA-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10033985", "catalyst" ] ], "additional_components": [ "A0A452DIN3", "ENSBTAT00000006132", "species_71067" ] }, "reaction_10041894": { "compartment": "compartment_70101", "id": "reaction_10041894", "reactome": "R-BTA-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10041891", "catalyst" ] ], "additional_components": [ "species_71185", "A0A3Q1LFW8", "ENSBTAT00000070085" ] }, "reaction_10090155": { "compartment": "compartment_70101", "id": "reaction_10090155", "reactome": "R-BTA-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_29356", "species_9014643" ], "modifiers": [ [ "species_10090152", "catalyst" ] ], "additional_components": [ "A5PKH5", "ENSBTAT00000011776" ] }, "reaction_10090162": { "compartment": "compartment_70101", "id": "reaction_10090162", "reactome": "R-BTA-9014641", "name": "HRSP12 deaminates 2AA to 2OBUTA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9014643" ], "products": [ "species_29382", "species_936714" ], "modifiers": [ [ "species_10090159", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016718" ] }, "reaction_10065455": { "compartment": "compartment_70101", "id": "reaction_10065455", "reactome": "R-BTA-2408524", "name": "Sec is reduced to H2Se by PXLP-K259-SCLY dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5359016", "species_5357697" ], "products": [ "species_5357660", "species_29432", "species_5359011" ], "modifiers": [ [ "species_10065452", "catalyst" ] ], "additional_components": [ "A2VDS1", "ENSBTAT00000013719" ] }, "reaction_10054601": { "compartment": "compartment_70101", "id": "reaction_10054601", "reactome": "R-BTA-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_29372", "species_200736" ], "modifiers": [ [ "species_10054598", "catalyst" ] ], "additional_components": [ "species_29926", "Q2KHU0", "ENSBTAT00000017392" ] }, "reaction_10054620": { "compartment": "compartment_70101", "id": "reaction_10054620", "reactome": "R-BTA-977348", "name": "PHGHD tetramer dehydrogenates 3PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29728" ], "products": [ "species_977329", "species_70106", "species_73473" ], "modifiers": [ [ "species_10054617", "catalyst" ] ], "additional_components": [ "A0A140T866", "ENSBTAT00000008907" ] }, "reaction_10090172": { "compartment": "compartment_70101", "id": "reaction_10090172", "reactome": "R-BTA-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10090175": { "compartment": "compartment_70101", "id": "reaction_10090175", "reactome": "R-BTA-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10054611": { "compartment": "compartment_70101", "id": "reaction_10054611", "reactome": "R-BTA-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977329", "species_29404" ], "products": [ "species_29406", "species_936706" ], "modifiers": [ [ "species_10054608", "catalyst" ] ], "additional_components": [ "A0A3S5ZPF7", "ENSBTAT00000018554" ] }, "reaction_10086371": { "compartment": "compartment_70101", "id": "reaction_10086371", "reactome": "R-BTA-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10086368", "catalyst" ] ], "additional_components": [ "A4FUZ5", "ENSBTAT00000002833", "A0A3Q1LF32", "ENSBTAT00000072137" ] }, "reaction_10090647": { "compartment": "compartment_70101", "id": "reaction_10090647", "reactome": "R-BTA-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10051165": { "compartment": "compartment_5460", "id": "reaction_10051165", "reactome": "R-BTA-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113593", "species_113600", "species_113552" ], "products": [ "species_113548", "species_113581", "species_31339", "species_113563" ], "modifiers": [ [ "species_10051162", "catalyst" ] ], "additional_components": [ "Q2KJH7", "ENSBTAT00000015703" ] }, "reaction_10077453": { "compartment": "compartment_70101", "id": "reaction_10077453", "reactome": "R-BTA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10077450", "catalyst" ] ], "additional_components": [ "Q58D08", "ENSBTAT00000022364" ] }, "reaction_10087455": { "compartment": "compartment_70101", "id": "reaction_10087455", "reactome": "R-BTA-8942575", "name": "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_5691492" ], "products": [ "species_29370", "species_5693762" ], "modifiers": [ [ "species_10087452", "catalyst" ] ], "additional_components": [ "Q0VCE9", "ENSBTAT00000004262", "F1N0M1", "ENSBTAT00000023262" ] }, "reaction_10052046": { "compartment": "compartment_70101", "id": "reaction_10052046", "reactome": "R-BTA-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29472" ], "products": [ "species_29432", "species_893598" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10077444": { "compartment": "compartment_5460", "id": "reaction_10077444", "reactome": "R-BTA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10077441", "catalyst" ] ], "additional_components": [ "Q17QJ7", "ENSBTAT00000000047" ] }, "reaction_10077864": { "compartment": "compartment_5460", "id": "reaction_10077864", "reactome": "R-BTA-6788611", "name": "HYKK phosphorylates 5HLYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788606", "species_113573" ], "products": [ "species_5696409", "species_113525" ], "modifiers": [ [ "species_10077861", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067508" ] }, "reaction_10077435": { "compartment": "compartment_17951", "id": "reaction_10077435", "reactome": "R-BTA-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_5693325" ], "products": [ "species_113575", "species_6783877" ], "modifiers": [ [ "species_10077432", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010444" ] }, "reaction_10045036": { "compartment": "compartment_5460", "id": "reaction_10045036", "reactome": "R-BTA-372480", "name": "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113577" ], "products": [ "species_29406", "species_70951" ], "modifiers": [ [ "species_10045033", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077809" ] }, "reaction_10051198": { "compartment": "compartment_5460", "id": "reaction_10051198", "reactome": "R-BTA-508561", "name": "alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70951", "species_113552" ], "products": [ "species_113594", "species_508531" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10076261": { "compartment": "compartment_17951", "id": "reaction_10076261", "reactome": "R-BTA-5693347", "name": "CRYM reduces P2C to PPCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_5693311", "species_113602" ], "products": [ "species_5693325", "species_389556" ], "modifiers": [ [ "species_10076258", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012972" ] }, "reaction_10033997": { "compartment": "compartment_17927", "id": "reaction_10033997", "reactome": "R-BTA-71275", "name": "arginine + glycine => ornithine + guanidoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113530", "species_113545" ], "products": [ "species_113543", "species_113586" ], "modifiers": [ [ "species_10033994", "catalyst" ] ], "additional_components": [ "Q2HJ74", "ENSBTAT00000007338" ] }, "reaction_10042847": { "compartment": "compartment_70616", "id": "reaction_10042847", "reactome": "R-BTA-200326", "name": "creatine + ATP => phosphocreatine + ADP [CK octamer]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042844", "catalyst" ] ], "additional_components": [ "Q9TTK8", "ENSBTAT00000009871" ] }, "reaction_10034004": { "compartment": "compartment_70101", "id": "reaction_10034004", "reactome": "R-BTA-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_29916", "species_70106", "species_71285" ], "modifiers": [ [ "species_10034001", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005375" ] }, "reaction_10042838": { "compartment": "compartment_70101", "id": "reaction_10042838", "reactome": "R-BTA-200318", "name": "creatine + ATP => phosphocreatine + ADP [CKB,CKM]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042835", "catalyst" ] ], "additional_components": [ "Q5EA61", "ENSBTAT00000050490" ] }, "reaction_10066232": { "compartment": "compartment_70101", "id": "reaction_10066232", "reactome": "R-BTA-2752067", "name": "BESTs transport cytosolic HCO3- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627" ], "products": [ "species_425425" ], "modifiers": [ [ "species_10066224", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10084767": { "compartment": "compartment_876", "id": "reaction_10084767", "reactome": "R-BTA-8863494", "name": "ASICs bind STOML3, (STOM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065958", "species_10084763" ], "products": [ "species_10084765" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "F1MCB3", "ENSBTAT00000024268", "F1MCB3", "ENSBTAT00000024268", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10091583": { "compartment": "compartment_70101", "id": "reaction_10091583", "reactome": "R-BTA-9659568", "name": "ANO1 transports cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065970", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067569" ] }, "reaction_10066206": { "compartment": "compartment_70101", "id": "reaction_10066206", "reactome": "R-BTA-2744242", "name": "TTYH2/3 transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066203", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080053" ] }, "reaction_10066270": { "compartment": "compartment_984", "id": "reaction_10066270", "reactome": "R-BTA-2872444", "name": "SLC9B1/C2 exchange Na+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10066267", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027774" ] }, "reaction_10066289": { "compartment": "compartment_17927", "id": "reaction_10066289", "reactome": "R-BTA-2889070", "name": "SLC9B2 exchanges Na+, Li+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_2889081" ], "products": [ "species_2889062", "species_163953" ], "modifiers": [ [ "species_10066286", "catalyst" ] ], "additional_components": [ "species_83910", "species_8953505", "species_8953505", "species_83910", "ENSBTAT00000085969" ] }, "reaction_10066227": { "compartment": "compartment_70101", "id": "reaction_10066227", "reactome": "R-BTA-2744361", "name": "BESTs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066224", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10066034": { "compartment": "compartment_70101", "id": "reaction_10066034", "reactome": "R-BTA-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_74722", "species_352022" ], "modifiers": [ [ "species_10066031", "catalyst" ] ], "additional_components": [ "G3N3A9", "ENSBTAT00000064202", "E1BK15", "ENSBTAT00000027587" ] }, "reaction_10066004": { "compartment": "compartment_161320", "id": "reaction_10066004", "reactome": "R-BTA-2685505", "name": "TPCN1/2 transport lysosomal Ca2+ to cytosol ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606834" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10066001", "catalyst" ], [ "species_2730676", "catalyst" ] ], "additional_components": [ "A0A3Q1MQ38", "ENSBTAT00000082890", "A0A3Q1N2G9", "ENSBTAT00000077727" ] }, "reaction_10066199": { "compartment": "compartment_70101", "id": "reaction_10066199", "reactome": "R-BTA-2744228", "name": "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066196", "catalyst" ] ], "additional_components": [ "E1BLQ0", "ENSBTAT00000012099", "E1BEP9", "ENSBTAT00000017615", "E1B792", "ENSBTAT00000049019" ] }, "reaction_10091542": { "compartment": "compartment_876", "id": "reaction_10091542", "reactome": "R-BTA-9650165", "name": "ASIC trimers bind H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10091540" ], "products": [ "species_10065958" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "F1MGK7", "ENSBTAT00000061078", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10066282": { "compartment": "compartment_70101", "id": "reaction_10066282", "reactome": "R-BTA-2872498", "name": "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_83910" ], "products": [ "species_113551", "species_2892454" ], "modifiers": [ [ "species_10066279", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065965": { "compartment": "compartment_70101", "id": "reaction_10065965", "reactome": "R-BTA-2671885", "name": "ASIC trimers:H+ transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10065958", "catalyst" ], [ "species_2672379", "inhibitor" ], [ "species_2672383", "inhibitor" ], [ "species_10065963", "inhibitor" ] ], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "ENSBTAT00000027364" ] }, "reaction_10066021": { "compartment": "compartment_70101", "id": "reaction_10066021", "reactome": "R-BTA-2730664", "name": "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10066018", "catalyst" ], [ "species_74016", "inhibitor" ] ], "additional_components": [ "A0A3Q1LL71", "ENSBTAT00000082451", "G3N0G4", "ENSBTAT00000065331", "F1MJ95", "ENSBTAT00000020495" ] }, "reaction_10066277": { "compartment": "compartment_70101", "id": "reaction_10066277", "reactome": "R-BTA-2872497", "name": "SLC17A3-2 transports cytosolic urate to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30034" ], "products": [ "species_429056" ], "modifiers": [ [ "species_10066274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065991": { "compartment": "compartment_70101", "id": "reaction_10065991", "reactome": "R-BTA-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065988", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A0A3Q1M2M7", "ENSBTAT00000073921", "E1BJF8", "ENSBTAT00000022706", "A0A3Q1MCG6", "ENSBTAT00000067569", "A0A3Q1LNC2", "ENSBTAT00000071379", "A0A3Q1MUE0", "ENSBTAT00000078140" ] }, "reaction_10049035": { "compartment": "compartment_70101", "id": "reaction_10049035", "reactome": "R-BTA-428917", "name": "G13 activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049028" ], "products": [ "species_29420", "species_10049032" ], "modifiers": [ [ "species_10049028", "catalyst" ] ], "additional_components": [ "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "G5E6P3", "ENSBTAT00000062941", "species_29438", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959" ] }, "reaction_10091701": { "compartment": "compartment_70101", "id": "reaction_10091701", "reactome": "R-BTA-9674529", "name": "AAMP binds to TBXA2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045856", "species_10091695" ], "products": [ "species_10091699" ], "modifiers": [ [ "species_391932", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000019892", "ENSBTAT00000005126", "Q3SZK1", "ENSBTAT00000005126", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10049014": { "compartment": "compartment_70101", "id": "reaction_10049014", "reactome": "R-BTA-428750", "name": "Gq activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049009" ], "products": [ "species_29420", "species_10049011" ], "modifiers": [ [ "species_10049009", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10048059": { "compartment": "compartment_70101", "id": "reaction_10048059", "reactome": "R-BTA-419003", "name": "Interaction of Nectins with Afadin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055", "species_10048049" ], "products": [ "species_10048057" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "ENSBTAT00000083796", "A0A3Q1LN46", "ENSBTAT00000083796", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048045": { "compartment": "compartment_204883", "id": "reaction_10048045", "reactome": "R-BTA-419001", "name": "Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_140648", "species_10048041" ], "products": [ "species_10048043" ], "modifiers": [], "additional_components": [ "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042", "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042" ] }, "reaction_10048348": { "compartment": "compartment_204883", "id": "reaction_10048348", "reactome": "R-BTA-420592", "name": "Transhomodimerization of Nectin-like (Necl) proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048344" ], "products": [ "species_10048346" ], "modifiers": [], "additional_components": [ "A0A3Q1M7P7", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841" ] }, "reaction_10048065": { "compartment": "compartment_204883", "id": "reaction_10048065", "reactome": "R-BTA-419011", "name": "Transhomodimerization of Nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048061" ], "products": [ "species_10048063" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048334": { "compartment": "compartment_204883", "id": "reaction_10048334", "reactome": "R-BTA-420584", "name": "Necl-1:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10048330" ], "products": [ "species_10048332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048352": { "compartment": "compartment_204883", "id": "reaction_10048352", "reactome": "R-BTA-420593", "name": "PVR:PVRL3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10042235" ], "products": [ "species_10048350" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070790", "A0A3Q1MRJ9", "ENSBTAT00000070790", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048342": { "compartment": "compartment_204883", "id": "reaction_10048342", "reactome": "R-BTA-420591", "name": "Nectin-2:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048338", "species_10048336" ], "products": [ "species_10048340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396" ] }, "reaction_10049335": { "compartment": "compartment_876", "id": "reaction_10049335", "reactome": "R-BTA-433711", "name": "Cis-homodimerization of nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055" ], "products": [ "species_10048061" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10044043": { "compartment": "compartment_70101", "id": "reaction_10044043", "reactome": "R-BTA-210294", "name": "Interaction of PECAM-1 and SHP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10044014" ], "products": [ "species_10044041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10049290": { "compartment": "compartment_70101", "id": "reaction_10049290", "reactome": "R-BTA-432148", "name": "Fgr may phosphorylate p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10049287", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "ENSBTAT00000078914" ] }, "reaction_10049283": { "compartment": "compartment_70101", "id": "reaction_10049283", "reactome": "R-BTA-432143", "name": "PECAM-1 binds PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041566", "species_10044014" ], "products": [ "species_10049281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044018": { "compartment": "compartment_70101", "id": "reaction_10044018", "reactome": "R-BTA-210277", "name": "Interaction of PECAM-1 and SHP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043836" ], "products": [ "species_10044016" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000077529", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10049364": { "compartment": "compartment_876", "id": "reaction_10049364", "reactome": "R-BTA-435244", "name": "PECAM1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044026" ], "products": [ "species_29370", "species_10044014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000086833" ] }, "reaction_10085323": { "compartment": "compartment_12045", "id": "reaction_10085323", "reactome": "R-BTA-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8869214" ], "products": [ "species_29416", "species_8869207" ], "modifiers": [ [ "species_10085320", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006727" ] }, "reaction_10048182": { "compartment": "compartment_984", "id": "reaction_10048182", "reactome": "R-BTA-419490", "name": "Binding of ATP to P2X receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037602", "species_114570" ], "products": [ "species_10037604" ], "modifiers": [], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10072426": { "compartment": "compartment_20699", "id": "reaction_10072426", "reactome": "R-BTA-5623513", "name": "ASAP1 stimulates GTPase activity of ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10072421" ], "products": [ "species_10072423", "species_29372", "species_10072399" ], "modifiers": [ [ "species_10072421", "catalyst" ] ], "additional_components": [ "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "P02699", "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072401": { "compartment": "compartment_70101", "id": "reaction_10072401", "reactome": "R-BTA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10072399" ], "products": [ "species_29420", "species_10072322" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10072326": { "compartment": "compartment_20699", "id": "reaction_10072326", "reactome": "R-BTA-5620914", "name": "ARF4:GTP binds VxPx-motifs of membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623403", "species_10072322" ], "products": [ "species_10072324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072475": { "compartment": "compartment_261122", "id": "reaction_10072475", "reactome": "R-BTA-5624127", "name": "ARL6:GTP and the BBSome target cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072451" ], "products": [ "species_10072467" ], "modifiers": [ [ "species_10072473", "inhibitor" ] ], "additional_components": [ "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072435": { "compartment": "compartment_70101", "id": "reaction_10072435", "reactome": "R-BTA-5624125", "name": "Formation of the BBSome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072245", "species_10072229", "species_10072257", "species_10072241", "species_10072253", "species_10072237", "species_10072249", "species_10072233" ], "products": [ "species_10072259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006505", "ENSBTAT00000026844", "ENSBTAT00000064380", "ENSBTAT00000014216", "ENSBTAT00000042964", "ENSBTAT00000010013", "ENSBTAT00000008587", "ENSBTAT00000032389", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072453": { "compartment": "compartment_876", "id": "reaction_10072453", "reactome": "R-BTA-5624126", "name": "ARL6:GTP and the BBSome bind ciliary cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072259", "species_10072449", "species_10072441" ], "products": [ "species_10072451" ], "modifiers": [], "additional_components": [ "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10057569": { "compartment": "compartment_876", "id": "reaction_10057569", "reactome": "R-BTA-1296127", "name": "Activation of voltage gated Potassium channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057566", "catalyst" ] ], "additional_components": [ "Q4PJK1", "ENSBTAT00000024576", "A2VDT0", "ENSBTAT00000019888", "E1B7K3", "ENSBTAT00000064709", "F1MLD6", "ENSBTAT00000022142", "F1MTJ1", "ENSBTAT00000009938", "F1N0E8", "ENSBTAT00000010960", "G3N1T8", "ENSBTAT00000065475", "F1MKB0", "ENSBTAT00000020543", "E1B9N0", "ENSBTAT00000021458", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1MFH2", "ENSBTAT00000086274", "A0A3Q1MPE6", "ENSBTAT00000074581", "E1BDC5", "ENSBTAT00000039169", "F1ML52", "ENSBTAT00000022193", "F1MJA9", "ENSBTAT00000018162", "E1BCM0", "ENSBTAT00000004406", "F1MC54", "ENSBTAT00000046307", "F1MP51", "ENSBTAT00000015122", "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "F1MPV7", "ENSBTAT00000010214", "E1BKI8", "ENSBTAT00000011681", "F1N553", "ENSBTAT00000007132", "A0A3Q1M6H7", "ENSBTAT00000071160", "A4FV89", "ENSBTAT00000028357", "F1MXZ4", "ENSBTAT00000011219", "E1BII8", "ENSBTAT00000023770", "E1B760", "ENSBTAT00000025668", "E1BLH0", "ENSBTAT00000005335", "F1MDM5", "ENSBTAT00000017003", "A0A3Q1LSF6", "ENSBTAT00000067149", "E1BMA2", "ENSBTAT00000022102" ] }, "reaction_10057365": { "compartment": "compartment_876", "id": "reaction_10057365", "reactome": "R-BTA-1296039", "name": "Activation of Ca2+ activated Potassium channels with small conductance", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057362", "catalyst" ] ], "additional_components": [ "E1BGY2", "ENSBTAT00000011376", "F1N467", "ENSBTAT00000014706" ] }, "reaction_10057665": { "compartment": "compartment_876", "id": "reaction_10057665", "reactome": "R-BTA-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057662", "catalyst" ] ], "additional_components": [ "F1MW24", "ENSBTAT00000020046" ] }, "reaction_10057656": { "compartment": "compartment_876", "id": "reaction_10057656", "reactome": "R-BTA-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057653", "catalyst" ] ], "additional_components": [ "A0A3Q1MT89", "ENSBTAT00000075452", "G3N1D1", "ENSBTAT00000063834" ] }, "reaction_10057682": { "compartment": "compartment_876", "id": "reaction_10057682", "reactome": "R-BTA-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057679", "catalyst" ] ], "additional_components": [ "Q8HZT2", "ENSBTAT00000013646", "E1BEH1", "ENSBTAT00000030656" ] }, "reaction_10057616": { "compartment": "compartment_876", "id": "reaction_10057616", "reactome": "R-BTA-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057613", "catalyst" ] ], "additional_components": [ "G3N1Q6", "ENSBTAT00000065420" ] }, "reaction_10090498": { "compartment": "compartment_70101", "id": "reaction_10090498", "reactome": "R-BTA-9027043", "name": "CYPs hydroxylate DHA to 14(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_9024011" ], "products": [ "species_29356", "species_29366", "species_9027049" ], "modifiers": [ [ "species_10090495", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "Q2KJJ2", "ENSBTAT00000000869", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10084300": { "compartment": "compartment_876", "id": "reaction_10084300", "reactome": "R-BTA-8854628", "name": "MYLIP dimer ubiquitinates VLDLR on Lys-839", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084266" ], "products": [ "species_10084295" ], "modifiers": [ [ "species_10084297", "catalyst" ], [ "species_10045642", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071362", "ENSBTAT00000071362", "A6QQD1", "ENSBTAT00000005377", "ENSBTAT00000071739" ] }, "reaction_10083113": { "compartment": "compartment_70101", "id": "reaction_10083113", "reactome": "R-BTA-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10083110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026745" ] }, "reaction_10085994": { "compartment": "compartment_161320", "id": "reaction_10085994", "reactome": "R-BTA-8876472", "name": "NPC2 binds CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085990", "species_8848047" ], "products": [ "species_10085992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029271", "species_193840", "P79345", "ENSBTAT00000029271" ] }, "reaction_10086026": { "compartment": "compartment_12045", "id": "reaction_10086026", "reactome": "R-BTA-8876696", "name": "SOAT1,2 transfer acyl group to CHOL forming CHEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384", "species_1500578" ], "products": [ "species_8876704", "species_76194" ], "modifiers": [ [ "species_10086023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033962" ] }, "reaction_10086557": { "compartment": "compartment_70101", "id": "reaction_10086557", "reactome": "R-BTA-8937442", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10086554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056670" ] }, "reaction_10086002": { "compartment": "compartment_161320", "id": "reaction_10086002", "reactome": "R-BTA-8876484", "name": "NPC2 transfers CHOL to NPC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085998", "species_10085992" ], "products": [ "species_10085990", "species_10086000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085568", "species_193840", "P79345", "ENSBTAT00000029271", "ENSBTAT00000029271", "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840" ] }, "reaction_10086004": { "compartment": "compartment_12045", "id": "reaction_10086004", "reactome": "R-BTA-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086000" ], "products": [ "species_193384", "species_10085998" ], "modifiers": [], "additional_components": [ "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840", "ENSBTAT00000085568" ] }, "reaction_10044020": { "compartment": "compartment_876", "id": "reaction_10044020", "reactome": "R-BTA-210282", "name": "Interaction of GPVI and FceRI gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037447", "species_10037453" ], "products": [ "species_10037455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426" ] }, "reaction_10049300": { "compartment": "compartment_70101", "id": "reaction_10049300", "reactome": "R-BTA-432295", "name": "GPVI binds Fyn and Lyn", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037463", "species_10037459", "species_10037455" ], "products": [ "species_10037465" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000015730", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10040521": { "compartment": "compartment_7660", "id": "reaction_10040521", "reactome": "R-BTA-187545", "name": "Association of Cks1 with SCF(Skp2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040517", "species_10040513" ], "products": [ "species_10040519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033975", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040542": { "compartment": "compartment_7660", "id": "reaction_10040542", "reactome": "R-BTA-187575", "name": "Ubiquitination of phospho-p27/p21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10040537" ], "products": [ "species_10040539" ], "modifiers": [ [ "species_10040537", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040576": { "compartment": "compartment_13231", "id": "reaction_10040576", "reactome": "R-BTA-187828", "name": "Translocation of p21 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040572" ], "products": [ "species_10040574" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011001", "ENSBTAT00000011001" ] }, "reaction_10040503": { "compartment": "compartment_13231", "id": "reaction_10040503", "reactome": "R-BTA-187506", "name": "Translocation of p27 to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499" ], "products": [ "species_10040501" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297" ] }, "reaction_10033512": { "compartment": "compartment_7660", "id": "reaction_10033512", "reactome": "R-BTA-69299", "name": "Cdt1 associates with geminin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033414", "species_10033508" ], "products": [ "species_10033510" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067336", "ENSBTAT00000023040", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336" ] }, "reaction_10033466": { "compartment": "compartment_7660", "id": "reaction_10033466", "reactome": "R-BTA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033462", "species_68419" ], "products": [ "species_10033464" ], "modifiers": [], "additional_components": [ "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798", "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798" ] }, "reaction_10087385": { "compartment": "compartment_70101", "id": "reaction_10087385", "reactome": "R-BTA-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087381", "species_10040351" ], "products": [ "species_10087383" ], "modifiers": [ [ "species_10040353", "inhibitor" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10056616": { "compartment": "compartment_7660", "id": "reaction_10056616", "reactome": "R-BTA-1226095", "name": "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056608" ], "products": [ "species_10056566", "species_113582", "species_10056614" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000015333", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057816": { "compartment": "compartment_7660", "id": "reaction_10057816", "reactome": "R-BTA-1363328", "name": "Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040519", "species_10056564" ], "products": [ "species_10057814" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10056602": { "compartment": "compartment_7660", "id": "reaction_10056602", "reactome": "R-BTA-1226094", "name": "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056559" ], "products": [ "species_113582", "species_10056566", "species_10056564" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000084739", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057821": { "compartment": "compartment_7660", "id": "reaction_10057821", "reactome": "R-BTA-1363331", "name": "Ubiquitination of p130 (RBL2) by SCF (Skp2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057814", "species_10036828" ], "products": [ "species_10040519", "species_10057818" ], "modifiers": [ [ "species_10057814", "catalyst" ] ], "additional_components": [ "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1M1Y7", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10087487": { "compartment": "compartment_70101", "id": "reaction_10087487", "reactome": "R-BTA-8942607", "name": "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087392" ], "products": [ "species_29370", "species_10087465" ], "modifiers": [ [ "species_10087484", "catalyst" ] ], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001" ] }, "reaction_10087503": { "compartment": "compartment_13231", "id": "reaction_10087503", "reactome": "R-BTA-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087491" ], "products": [ "species_10087501" ], "modifiers": [], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10087394": { "compartment": "compartment_70101", "id": "reaction_10087394", "reactome": "R-BTA-8941915", "name": "Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087383", "species_10087390" ], "products": [ "species_10087392" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277" ] }, "reaction_10065794": { "compartment": "compartment_70101", "id": "reaction_10065794", "reactome": "R-BTA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065782", "species_29356" ], "products": [ "species_29372", "species_10065792" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562", "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10035745": { "compartment": "compartment_13231", "id": "reaction_10035745", "reactome": "R-BTA-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035737" ], "products": [ "species_10035743" ], "modifiers": [], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10035747": { "compartment": "compartment_13231", "id": "reaction_10035747", "reactome": "R-BTA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035731" ], "products": [ "species_10035739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023277", "ENSBTAT00000023277" ] }, "reaction_10074692": { "compartment": "compartment_7660", "id": "reaction_10074692", "reactome": "R-BTA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074688" ], "products": [ "species_10074690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10074695": { "compartment": "compartment_7660", "id": "reaction_10074695", "reactome": "R-BTA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074690" ], "products": [ "species_113582", "species_10033532" ], "modifiers": [ [ "species_10074690", "catalyst" ] ], "additional_components": [ "F6R5E4", "ENSBTAT00000006518", "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10051465": { "compartment": "compartment_7660", "id": "reaction_10051465", "reactome": "R-BTA-606349", "name": "Mis18 complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051445", "species_10051395" ], "products": [ "species_10051453" ], "modifiers": [], "additional_components": [ "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256" ] }, "reaction_10051451": { "compartment": "compartment_7660", "id": "reaction_10051451", "reactome": "R-BTA-606287", "name": "RSF complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051447", "species_10051335" ], "products": [ "species_10051431", "species_10051445", "species_10051449" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10051461": { "compartment": "compartment_7660", "id": "reaction_10051461", "reactome": "R-BTA-606289", "name": "New CENPA-containing nucleosomes are deposited at the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035218", "species_10051459", "species_10035105" ], "products": [ "species_10051447" ], "modifiers": [], "additional_components": [ "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10051463": { "compartment": "compartment_7660", "id": "reaction_10051463", "reactome": "R-BTA-606326", "name": "HJURP:CENPA complex localizes to the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051457", "species_10051453" ], "products": [ "species_10051459" ], "modifiers": [], "additional_components": [ "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10058792": { "compartment": "compartment_70101", "id": "reaction_10058792", "reactome": "R-BTA-1475436", "name": "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057070": { "compartment": "compartment_70101", "id": "reaction_10057070", "reactome": "R-BTA-1247668", "name": "Hemoglobin A binds O2, releasing H+ and CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057060", "species_29368" ], "products": [ "species_10057046", "species_70106", "species_113528" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323" ] }, "reaction_10063560": { "compartment": "compartment_7660", "id": "reaction_10063560", "reactome": "R-BTA-2065539", "name": "SREBP1A,1C,2:Importin beta-1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043501", "species_10060344" ], "products": [ "species_10063558", "species_10060342" ], "modifiers": [], "additional_components": [ "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063562": { "compartment": "compartment_70101", "id": "reaction_10063562", "reactome": "R-BTA-2065549", "name": "SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060328" ], "products": [ "species_10060330" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10060346": { "compartment": "compartment_70101", "id": "reaction_10060346", "reactome": "R-BTA-1655831", "name": "SREBP1A,1C,2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060332" ], "products": [ "species_10060344" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063564": { "compartment": "compartment_70101", "id": "reaction_10063564", "reactome": "R-BTA-2065550", "name": "SREBP1A,1C,2 binds Importin beta-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10060330" ], "products": [ "species_10060332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10090604": { "compartment": "compartment_17951", "id": "reaction_10090604", "reactome": "R-BTA-9033520", "name": "TYSND1 cleaves TYSND1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_10090597" ], "products": [ "species_10090599", "species_10090601" ], "modifiers": [ [ "species_10090597", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816" ] }, "reaction_10037293": { "compartment": "compartment_70101", "id": "reaction_10037293", "reactome": "R-BTA-114392", "name": "Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037287" ], "products": [ "species_10037229", "species_10037291" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10090504": { "compartment": "compartment_70101", "id": "reaction_10090504", "reactome": "R-BTA-9027532", "name": "PTGS2 dimer oxidises DHA to 13-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027547" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090506": { "compartment": "compartment_70101", "id": "reaction_10090506", "reactome": "R-BTA-9027607", "name": "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9027614" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090508": { "compartment": "compartment_70101", "id": "reaction_10090508", "reactome": "R-BTA-9027627", "name": "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027622" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090510": { "compartment": "compartment_70101", "id": "reaction_10090510", "reactome": "R-BTA-9028255", "name": "PTGS2 dimer oxidises EPA to PGH3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9028280" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10075037": { "compartment": "compartment_7660", "id": "reaction_10075037", "reactome": "R-BTA-5685953", "name": "SIRT6 deacetylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075030", "species_427523" ], "products": [ "species_427497", "species_427498", "species_10074778" ], "modifiers": [ [ "species_10075034", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "ENSBTAT00000026521" ] }, "reaction_10074798": { "compartment": "compartment_7660", "id": "reaction_10074798", "reactome": "R-BTA-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074795" ], "products": [ "species_113582", "species_10074789" ], "modifiers": [ [ "species_10074795", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076339": { "compartment": "compartment_7660", "id": "reaction_10076339", "reactome": "R-BTA-5693608", "name": "Initial resection of double-strand break ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076336" ], "products": [ "species_30555", "species_10075051" ], "modifiers": [ [ "species_10076336", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498" ] }, "reaction_10060476": { "compartment": "compartment_12045", "id": "reaction_10060476", "reactome": "R-BTA-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10060456", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047316" ] }, "reaction_10083369": { "compartment": "compartment_876", "id": "reaction_10083369", "reactome": "R-BTA-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10083366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015375" ] }, "reaction_10083211": { "compartment": "compartment_12045", "id": "reaction_10083211", "reactome": "R-BTA-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6814253" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10083208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084401" ] }, "reaction_10082931": { "compartment": "compartment_172574", "id": "reaction_10082931", "reactome": "R-BTA-6810392", "name": "TMEM55B translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082927" ], "products": [ "species_10082929" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003561", "ENSBTAT00000003561" ] }, "reaction_10083092": { "compartment": "compartment_7660", "id": "reaction_10083092", "reactome": "R-BTA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10083089", "catalyst" ] ], "additional_components": [ "F1MHT2", "ENSBTAT00000008517", "F1MHR4", "ENSBTAT00000024007" ] }, "reaction_10082934": { "compartment": "compartment_7660", "id": "reaction_10082934", "reactome": "R-BTA-6810410", "name": "PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_6810412" ], "products": [ "species_6810408", "species_113550" ], "modifiers": [ [ "species_10082929", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003561" ] }, "reaction_10060569": { "compartment": "compartment_876", "id": "reaction_10060569", "reactome": "R-BTA-1676109", "name": "PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060566", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "E1B8D1", "ENSBTAT00000043102", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MBU9", "ENSBTAT00000017388", "species_113527" ] }, "reaction_10060473": { "compartment": "compartment_876", "id": "reaction_10060473", "reactome": "R-BTA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082136": { "compartment": "compartment_70101", "id": "reaction_10082136", "reactome": "R-BTA-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10082128" ], "products": [ "species_10082134" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000050192", "F1ME94", "ENSBTAT00000050192", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060600": { "compartment": "compartment_876", "id": "reaction_10060600", "reactome": "R-BTA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10085784": { "compartment": "compartment_171062", "id": "reaction_10085784", "reactome": "R-BTA-8871376", "name": "p-Y281,292-RUFY1 binds PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085767", "species_1806200" ], "products": [ "species_10085782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "species_5693050", "F6R352", "ENSBTAT00000000317" ] }, "reaction_10060572": { "compartment": "compartment_876", "id": "reaction_10060572", "reactome": "R-BTA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060595": { "compartment": "compartment_876", "id": "reaction_10060595", "reactome": "R-BTA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10060592", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BLB5", "ENSBTAT00000022635" ] }, "reaction_10085780": { "compartment": "compartment_70101", "id": "reaction_10085780", "reactome": "R-BTA-8871373", "name": "BMX phosphorylates RUFY1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10085777" ], "products": [ "species_29370", "species_10085773" ], "modifiers": [ [ "species_10044855", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317", "ENSBTAT00000000488" ] }, "reaction_10060535": { "compartment": "compartment_876", "id": "reaction_10060535", "reactome": "R-BTA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10082152": { "compartment": "compartment_876", "id": "reaction_10082152", "reactome": "R-BTA-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10082155": { "compartment": "compartment_876", "id": "reaction_10082155", "reactome": "R-BTA-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10060429": { "compartment": "compartment_876", "id": "reaction_10060429", "reactome": "R-BTA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060461": { "compartment": "compartment_876", "id": "reaction_10060461", "reactome": "R-BTA-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10085775": { "compartment": "compartment_70101", "id": "reaction_10085775", "reactome": "R-BTA-8871370", "name": "p-Y281,292-RUFY1 translocates from cytosol to early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085773" ], "products": [ "species_10085767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317" ] }, "reaction_10060590": { "compartment": "compartment_876", "id": "reaction_10060590", "reactome": "R-BTA-1676164", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_202247" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10085697": { "compartment": "compartment_876", "id": "reaction_10085697", "reactome": "R-BTA-8870489", "name": "PLEKHA4,(5,6) bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_10085693" ], "products": [ "species_10085695" ], "modifiers": [], "additional_components": [ "E1B7V8", "ENSBTAT00000061135", "E1B7V8", "ENSBTAT00000061135", "species_5693050" ] }, "reaction_10060579": { "compartment": "compartment_876", "id": "reaction_10060579", "reactome": "R-BTA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060576", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082147": { "compartment": "compartment_70101", "id": "reaction_10082147", "reactome": "R-BTA-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10060526" ], "products": [ "species_10082145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000069408", "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060514": { "compartment": "compartment_876", "id": "reaction_10060514", "reactome": "R-BTA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10060511", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10060550": { "compartment": "compartment_876", "id": "reaction_10060550", "reactome": "R-BTA-1676048", "name": "PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060547", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10083800": { "compartment": "compartment_70101", "id": "reaction_10083800", "reactome": "R-BTA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10083797", "catalyst" ] ], "additional_components": [ "species_179838", "species_1806238", "species_6810412", "species_5693050", "species_1806205", "species_1806259", "ENSBTAT00000029059" ] }, "reaction_10060588": { "compartment": "compartment_171062", "id": "reaction_10060588", "reactome": "R-BTA-1676162", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806238" ], "products": [ "species_29372", "species_1806200" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10060558": { "compartment": "compartment_171062", "id": "reaction_10060558", "reactome": "R-BTA-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806205" ], "products": [ "species_29372", "species_1806259" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060574": { "compartment": "compartment_171062", "id": "reaction_10060574", "reactome": "R-BTA-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_29372", "species_1806199" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060501": { "compartment": "compartment_171062", "id": "reaction_10060501", "reactome": "R-BTA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060518": { "compartment": "compartment_171062", "id": "reaction_10060518", "reactome": "R-BTA-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_1806180", "species_29370" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060614": { "compartment": "compartment_171062", "id": "reaction_10060614", "reactome": "R-BTA-1676206", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806180", "species_113592" ], "products": [ "species_29370", "species_1806238" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060611": { "compartment": "compartment_20699", "id": "reaction_10060611", "reactome": "R-BTA-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060608", "catalyst" ] ], "additional_components": [ "A0A3Q1MHQ7", "ENSBTAT00000081928" ] }, "reaction_10060483": { "compartment": "compartment_20699", "id": "reaction_10060483", "reactome": "R-BTA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001784" ] }, "reaction_10060498": { "compartment": "compartment_20699", "id": "reaction_10060498", "reactome": "R-BTA-1675928", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806217" ], "products": [ "species_1806230", "species_29370" ], "modifiers": [ [ "species_10060495", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "E1B8D1", "ENSBTAT00000043102" ] }, "reaction_10060597": { "compartment": "compartment_20699", "id": "reaction_10060597", "reactome": "R-BTA-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060516": { "compartment": "compartment_20699", "id": "reaction_10060516", "reactome": "R-BTA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10085843": { "compartment": "compartment_437051", "id": "reaction_10085843", "reactome": "R-BTA-8874470", "name": "TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8874484" ], "products": [ "species_8874460" ], "modifiers": [ [ "species_10085840", "catalyst" ] ], "additional_components": [ "species_179838", "species_6810412", "species_6810412", "species_179838", "A0A3Q1LVF0", "ENSBTAT00000072298" ] }, "reaction_10040152": { "compartment": "compartment_70101", "id": "reaction_10040152", "reactome": "R-BTA-176664", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176575", "species_158471" ], "products": [ "species_176501", "species_158466" ], "modifiers": [ [ "species_10040149", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040120": { "compartment": "compartment_70101", "id": "reaction_10040120", "reactome": "R-BTA-176588", "name": "lithocholate + PAPS => lithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_158471" ], "products": [ "species_176555", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040122": { "compartment": "compartment_70101", "id": "reaction_10040122", "reactome": "R-BTA-176604", "name": "taurolithocholate + PAPS => taurolithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176565", "species_158471" ], "products": [ "species_176483", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040157": { "compartment": "compartment_70101", "id": "reaction_10040157", "reactome": "R-BTA-176669", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176566" ], "products": [ "species_176500", "species_158466" ], "modifiers": [ [ "species_10040154", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388" ] }, "reaction_10076799": { "compartment": "compartment_70101", "id": "reaction_10076799", "reactome": "R-BTA-5695964", "name": "ABHD14B hydrolyses PNPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695960", "species_29356" ], "products": [ "species_5695950", "species_76179" ], "modifiers": [ [ "species_10076796", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024782" ] }, "reaction_10038320": { "compartment": "compartment_70101", "id": "reaction_10038320", "reactome": "R-BTA-158860", "name": "SULT1A1 dimer sulfonates NHABP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158847", "species_158471" ], "products": [ "species_158859", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040112": { "compartment": "compartment_70101", "id": "reaction_10040112", "reactome": "R-BTA-176517", "name": "SULTs transfer (SO4)2- group to PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_158471" ], "products": [ "species_176665", "species_158466" ], "modifiers": [ [ "species_10040109", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040147": { "compartment": "compartment_70101", "id": "reaction_10040147", "reactome": "R-BTA-176646", "name": "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695950", "species_158471" ], "products": [ "species_176600", "species_158466" ], "modifiers": [ [ "species_10040144", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "P50227", "ENSBTAT00000011388" ] }, "reaction_10040115": { "compartment": "compartment_70101", "id": "reaction_10040115", "reactome": "R-BTA-176521", "name": "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_158471" ], "products": [ "species_176492", "species_158466" ], "modifiers": [ [ "species_10040075", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040117": { "compartment": "compartment_70101", "id": "reaction_10040117", "reactome": "R-BTA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176667", "species_158471" ], "products": [ "species_176564", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038231": { "compartment": "compartment_70101", "id": "reaction_10038231", "reactome": "R-BTA-158468", "name": "SULT1A1 dimer sulfonates PARA to PARA-SO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158469", "species_158471" ], "products": [ "species_158472", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088617": { "compartment": "compartment_17963", "id": "reaction_10088617", "reactome": "R-BTA-8954262", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10088606" ], "products": [ "species_742343", "species_10088610" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043559", "ENSBTAT00000043559", "ENSBTAT00000000502" ] }, "reaction_10040136": { "compartment": "compartment_70101", "id": "reaction_10040136", "reactome": "R-BTA-176631", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176626" ], "products": [ "species_176496", "species_158466" ], "modifiers": [ [ "species_10040133", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040107": { "compartment": "compartment_70101", "id": "reaction_10040107", "reactome": "R-BTA-176494", "name": "SULTs transfer (SO4)2- group to 27HCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176617", "species_158471" ], "products": [ "species_176502", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10038318": { "compartment": "compartment_70101", "id": "reaction_10038318", "reactome": "R-BTA-158849", "name": "Phenol can form a sulfate conjugate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158858", "species_158471" ], "products": [ "species_158466", "species_158850" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040129": { "compartment": "compartment_70101", "id": "reaction_10040129", "reactome": "R-BTA-176606", "name": "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_158466" ], "products": [ "species_29372", "species_76577" ], "modifiers": [ [ "species_10040126", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005311" ] }, "reaction_10040131": { "compartment": "compartment_70101", "id": "reaction_10040131", "reactome": "R-BTA-176609", "name": "cholesterol + PAPS => cholesterol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_158471" ], "products": [ "species_176618", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10040098": { "compartment": "compartment_70101", "id": "reaction_10040098", "reactome": "R-BTA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176486" ], "products": [ "species_176519", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038340": { "compartment": "compartment_70101", "id": "reaction_10038340", "reactome": "R-BTA-159358", "name": "SULT1A3,4 dimers sulfate DA to DAOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_159362" ], "products": [ "species_159352", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088580": { "compartment": "compartment_17963", "id": "reaction_10088580", "reactome": "R-BTA-8953499", "name": "IMPAD1 hydrolyses PAP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742343", "species_2022884" ], "products": [ "species_8851226", "species_8953493" ], "modifiers": [ [ "species_10088577", "catalyst" ], [ "species_8953505", "inhibitor" ] ], "additional_components": [ "species_29926", "A0A452DIR7", "ENSBTAT00000020766" ] }, "reaction_10050342": { "compartment": "compartment_70101", "id": "reaction_10050342", "reactome": "R-BTA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10050336" ], "products": [ "species_10050340" ], "modifiers": [], "additional_components": [ "A0A3Q1M8I4", "ENSBTAT00000075547", "A0A3Q1M8I4", "ENSBTAT00000075547" ] }, "reaction_10082923": { "compartment": "compartment_7660", "id": "reaction_10082923", "reactome": "R-BTA-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_10069400" ], "products": [ "species_10082921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "species_1806259" ] }, "reaction_10086155": { "compartment": "compartment_7660", "id": "reaction_10086155", "reactome": "R-BTA-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086151", "species_10053086" ], "products": [ "species_10086153" ], "modifiers": [], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10083072": { "compartment": "compartment_7660", "id": "reaction_10083072", "reactome": "R-BTA-6811479", "name": "ING2 recruits EP300 to TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10053052", "species_10069400" ], "products": [ "species_10083070" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021556", "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10083077": { "compartment": "compartment_7660", "id": "reaction_10083077", "reactome": "R-BTA-6811508", "name": "ING2-bound EP300 acetylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10083070" ], "products": [ "species_2485002", "species_10083074" ], "modifiers": [ [ "species_10083070", "catalyst" ], [ "species_6810408", "catalyst" ] ], "additional_components": [ "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10090593": { "compartment": "compartment_70101", "id": "reaction_10090593", "reactome": "R-BTA-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090579", "species_10090589" ], "products": [ "species_10090591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022338", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "Q08DL6", "ENSBTAT00000022338" ] }, "reaction_10090770": { "compartment": "compartment_70101", "id": "reaction_10090770", "reactome": "R-BTA-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090766", "species_10090732" ], "products": [ "species_10090768" ], "modifiers": [], "additional_components": [ "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885", "ENSBTAT00000009921", "Q3SZD1", "ENSBTAT00000009921", "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885" ] }, "reaction_10039049": { "compartment": "compartment_5460", "id": "reaction_10039049", "reactome": "R-BTA-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10039037" ], "products": [ "species_10039039" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039044": { "compartment": "compartment_5460", "id": "reaction_10039044", "reactome": "R-BTA-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039039" ], "products": [ "species_10039041", "species_113521" ], "modifiers": [ [ "species_10039039", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039047": { "compartment": "compartment_5460", "id": "reaction_10039047", "reactome": "R-BTA-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039041", "species_163953" ], "products": [ "species_113529", "species_113593", "species_10039037" ], "modifiers": [ [ "species_10039041", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592" ] }, "reaction_10035417": { "compartment": "compartment_5460", "id": "reaction_10035417", "reactome": "R-BTA-74181", "name": "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_73871" ], "products": [ "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10035374": { "compartment": "compartment_5460", "id": "reaction_10035374", "reactome": "R-BTA-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_73911" ], "products": [ "species_113529", "species_73909", "species_29362" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10035415": { "compartment": "compartment_5460", "id": "reaction_10035415", "reactome": "R-BTA-74177", "name": "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_73909" ], "products": [ "species_73871", "species_113536" ], "modifiers": [ [ "species_10035412", "catalyst" ] ], "additional_components": [ "A0A3Q1LIX4", "ENSBTAT00000077723" ] }, "reaction_10065944": { "compartment": "compartment_2514888", "id": "reaction_10065944", "reactome": "R-BTA-2632521", "name": "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035617" ], "products": [ "species_10065942", "species_2466098" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10035596": { "compartment": "compartment_2514888", "id": "reaction_10035596", "reactome": "R-BTA-74885", "name": "GUCYs converts GTP to cGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438" ], "products": [ "species_111294", "species_30991" ], "modifiers": [ [ "species_10035583", "catalyst" ], [ "species_10035592", "catalyst" ], [ "species_10035594", "inhibitor" ], [ "species_10035590", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000011564", "ENSBTAT00000087322", "P46065", "ENSBTAT00000087322", "species_74016", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10065808": { "compartment": "compartment_70101", "id": "reaction_10065808", "reactome": "R-BTA-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065796", "species_2534019" ], "products": [ "species_10065799", "species_76194" ], "modifiers": [ [ "species_10065805", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023990", "ENSBTAT00000023990", "Q9N181", "ENSBTAT00000050460", "F1MZK0", "ENSBTAT00000007950" ] }, "reaction_10035619": { "compartment": "compartment_2514888", "id": "reaction_10035619", "reactome": "R-BTA-74948", "name": "PP2A dephosphorylates p-RHO to RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035601" ], "products": [ "species_29372", "species_2565923" ], "modifiers": [ [ "species_10035607", "catalyst" ], [ "species_74016", "catalyst" ], [ "species_10035617", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730", "species_29926", "F1MBQ1", "ENSBTAT00000068795", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10065940": { "compartment": "compartment_70101", "id": "reaction_10065940", "reactome": "R-BTA-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035588", "species_74016" ], "products": [ "species_10035590" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087322", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10078600": { "compartment": "compartment_876", "id": "reaction_10078600", "reactome": "R-BTA-6797974", "name": "LRRTMs bind NRXNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078596", "species_10078418" ], "products": [ "species_10078598" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078488": { "compartment": "compartment_70101", "id": "reaction_10078488", "reactome": "R-BTA-6797553", "name": "Protein 4.1 binds CASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078484", "species_10071423" ], "products": [ "species_10078486" ], "modifiers": [], "additional_components": [ "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "ENSBTAT00000071329", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078522": { "compartment": "compartment_876", "id": "reaction_10078522", "reactome": "R-BTA-6797568", "name": "NRXNs bind CASK:Protein 4.1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078486", "species_10078444" ], "products": [ "species_10078520" ], "modifiers": [], "additional_components": [ "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078446": { "compartment": "compartment_876", "id": "reaction_10078446", "reactome": "R-BTA-6794346", "name": "NRXNs bind NLGNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078418", "species_10078442" ], "products": [ "species_10078444" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078464": { "compartment": "compartment_876", "id": "reaction_10078464", "reactome": "R-BTA-6794347", "name": "Homer1,2,3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078458", "species_10078456" ], "products": [ "species_10078462" ], "modifiers": [], "additional_components": [ "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078466": { "compartment": "compartment_876", "id": "reaction_10078466", "reactome": "R-BTA-6794355", "name": "Homer1,2,3 binds mGluR1a,5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045110", "species_10078456" ], "products": [ "species_10078458" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078518": { "compartment": "compartment_876", "id": "reaction_10078518", "reactome": "R-BTA-6797554", "name": "ABP1 binds SHANK proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078514", "species_10043423" ], "products": [ "species_10078516" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330", "ENSBTAT00000023325", "A0A452DIT4", "ENSBTAT00000023325", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330" ] }, "reaction_10046648": { "compartment": "compartment_70101", "id": "reaction_10046648", "reactome": "R-BTA-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046644" ], "products": [ "species_10046646", "species_29420" ], "modifiers": [ [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ] ], "additional_components": [ "species_29420", "P62833", "ENSBTAT00000068678", "P62833", "ENSBTAT00000068678", "species_29438", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046623": { "compartment": "compartment_876", "id": "reaction_10046623", "reactome": "R-BTA-381608", "name": "cAMP activates EPAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044624", "species_30389" ], "products": [ "species_10044626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061074", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046642": { "compartment": "compartment_876", "id": "reaction_10046642", "reactome": "R-BTA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046640" ], "products": [ "species_10046640" ], "modifiers": [], "additional_components": [ "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162", "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162" ] }, "reaction_10046630": { "compartment": "compartment_876", "id": "reaction_10046630", "reactome": "R-BTA-381668", "name": "cAMP activates EPAC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044630", "species_30389" ], "products": [ "species_10044632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085533", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10043885": { "compartment": "compartment_876", "id": "reaction_10043885", "reactome": "R-BTA-209738", "name": "VD3 binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209767", "species_10043881" ], "products": [ "species_10043883" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870" ] }, "reaction_10043903": { "compartment": "compartment_70101", "id": "reaction_10043903", "reactome": "R-BTA-209760", "name": "Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043895" ], "products": [ "species_10043901" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "A0A3Q1LQ02", "ENSBTAT00000075079", "F1MKV7", "ENSBTAT00000039417", "species_209804" ] }, "reaction_10088926": { "compartment": "compartment_984", "id": "reaction_10088926", "reactome": "R-BTA-8963851", "name": "VD3 dissociates from GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043883" ], "products": [ "species_209767", "species_10043881" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870", "ENSBTAT00000075079" ] }, "reaction_10043984": { "compartment": "compartment_984", "id": "reaction_10043984", "reactome": "R-BTA-209944", "name": "25(OH)D binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209906", "species_10043881" ], "products": [ "species_10043982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10088928": { "compartment": "compartment_161320", "id": "reaction_10088928", "reactome": "R-BTA-8963864", "name": "CUBN dissociates from 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044728" ], "products": [ "species_350136", "species_10043899" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "species_209804", "ENSBTAT00000039417" ] }, "reaction_10044739": { "compartment": "compartment_876", "id": "reaction_10044739", "reactome": "R-BTA-350168", "name": "LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044732" ], "products": [ "species_10043895" ], "modifiers": [ [ "species_10044736", "catalyst" ] ], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000005988" ] }, "reaction_10044741": { "compartment": "compartment_984", "id": "reaction_10044741", "reactome": "R-BTA-350186", "name": "CUBN binds GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043982", "species_10044730" ], "products": [ "species_10044732" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000039417", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10043910": { "compartment": "compartment_70616", "id": "reaction_10043910", "reactome": "R-BTA-209765", "name": "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_209800", "species_29368", "species_29364" ], "products": [ "species_29356", "species_350159", "species_29366" ], "modifiers": [ [ "species_10043907", "catalyst" ], [ "species_29532", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10040922": { "compartment": "compartment_70101", "id": "reaction_10040922", "reactome": "R-BTA-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191265" ], "products": [ "species_111294", "species_191269", "species_29366" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10041664": { "compartment": "compartment_70101", "id": "reaction_10041664", "reactome": "R-BTA-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_195691", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_195655" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10041728": { "compartment": "compartment_70101", "id": "reaction_10041728", "reactome": "R-BTA-196417", "name": "Reduction of desmosterol to cholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_196420", "species_29364" ], "products": [ "species_193384", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041671": { "compartment": "compartment_12045", "id": "reaction_10041671", "reactome": "R-BTA-195690", "name": "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194691" ], "products": [ "species_195691" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10040892": { "compartment": "compartment_70101", "id": "reaction_10040892", "reactome": "R-BTA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10040924": { "compartment": "compartment_70101", "id": "reaction_10040924", "reactome": "R-BTA-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_111294", "species_191265" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10040895": { "compartment": "compartment_70101", "id": "reaction_10040895", "reactome": "R-BTA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10041502": { "compartment": "compartment_70101", "id": "reaction_10041502", "reactome": "R-BTA-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194657", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194661", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10040913": { "compartment": "compartment_70101", "id": "reaction_10040913", "reactome": "R-BTA-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10040910", "catalyst" ] ], "additional_components": [ "A0A140T853", "ENSBTAT00000005323", "species_29926" ] }, "reaction_10040881": { "compartment": "compartment_70101", "id": "reaction_10040881", "reactome": "R-BTA-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_191269", "species_29364" ], "products": [ "species_191309", "species_29356", "species_29366" ], "modifiers": [ [ "species_10040878", "catalyst" ] ], "additional_components": [ "A5D9A8", "ENSBTAT00000007228", "species_113596" ] }, "reaction_10088019": { "compartment": "compartment_70101", "id": "reaction_10088019", "reactome": "R-BTA-8952137", "name": "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_191265" ], "products": [ "species_8952135", "species_29372" ], "modifiers": [ [ "species_10088016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014674" ] }, "reaction_10041493": { "compartment": "compartment_13231", "id": "reaction_10041493", "reactome": "R-BTA-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194725", "species_194688" ], "products": [ "species_194668", "species_194704" ], "modifiers": [ [ "species_10041490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011125" ] }, "reaction_10083496": { "compartment": "compartment_70101", "id": "reaction_10083496", "reactome": "R-BTA-8848215", "name": "ACAT2 condenses 2 Ac-CoA to form ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_191293", "species_29356", "species_76194" ], "modifiers": [ [ "species_10083493", "catalyst" ] ], "additional_components": [ "A0A3Q1MLP4", "ENSBTAT00000012548" ] }, "reaction_10040904": { "compartment": "compartment_70101", "id": "reaction_10040904", "reactome": "R-BTA-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191374", "species_70106", "species_29364" ], "products": [ "species_29366", "species_76194", "species_191424" ], "modifiers": [ [ "species_10040901", "catalyst" ] ], "additional_components": [ "A7Z064", "ENSBTAT00000010315" ] }, "reaction_10041484": { "compartment": "compartment_70101", "id": "reaction_10041484", "reactome": "R-BTA-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194667", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10041486": { "compartment": "compartment_70101", "id": "reaction_10041486", "reactome": "R-BTA-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_194723" ], "products": [ "species_29356", "species_29366", "species_194657" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10081986": { "compartment": "compartment_12045", "id": "reaction_10081986", "reactome": "R-BTA-6807052", "name": "EBP isomerizes ZYMSTNL to LTHSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807048" ], "products": [ "species_6807054" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10081988": { "compartment": "compartment_12045", "id": "reaction_10081988", "reactome": "R-BTA-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6807054", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6807057" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10081990": { "compartment": "compartment_12045", "id": "reaction_10081990", "reactome": "R-BTA-6807064", "name": "DHCR24 reduces ZYMOL to ZYMSTNL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194691" ], "products": [ "species_6807048", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041477": { "compartment": "compartment_70101", "id": "reaction_10041477", "reactome": "R-BTA-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194644", "species_29364" ], "products": [ "species_194735", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10038347": { "compartment": "compartment_70101", "id": "reaction_10038347", "reactome": "R-BTA-159425", "name": "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_194096" ], "products": [ "species_111294", "species_29356", "species_194073", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "species_193451", "CHEBI:16755", "species_192356", "CHEBI:28701", "ENSBTAT00000020170" ] }, "reaction_10041437": { "compartment": "compartment_876", "id": "reaction_10041437", "reactome": "R-BTA-194187", "name": "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041428", "species_192483", "species_74113" ], "products": [ "species_10041430", "species_83910" ], "modifiers": [ [ "species_10041434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014054", "CHEBI:17687", "CHEBI:28865", "CHEBI:16755", "CHEBI:36274", "species_193451", "CHEBI:9407", "A0A452DID8", "ENSBTAT00000014054", "species_193451", "CHEBI:17687", "CHEBI:36274", "CHEBI:16525", "CHEBI:16755", "CHEBI:28865", "ENSBTAT00000021363" ] }, "reaction_10085806": { "compartment": "compartment_70101", "id": "reaction_10085806", "reactome": "R-BTA-8873850", "name": "STARD5 binds DCA, LCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_10085802", "species_5357505" ], "products": [ "species_10085804" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014559", "species_5357505", "A1A4M6", "ENSBTAT00000014559", "species_176655" ] }, "reaction_10085291": { "compartment": "compartment_70101", "id": "reaction_10085291", "reactome": "R-BTA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10085288", "catalyst" ] ], "additional_components": [ "A0A3Q1LYV2", "ENSBTAT00000083446", "E1BBD8", "ENSBTAT00000017982", "E1BL67", "ENSBTAT00000044841", "A0A3Q1M0E7", "ENSBTAT00000066543", "A0A3Q1MW81", "ENSBTAT00000066543" ] }, "reaction_10041097": { "compartment": "compartment_70101", "id": "reaction_10041097", "reactome": "R-BTA-191972", "name": "27-hydroxycholesterol is 7alpha-hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_176617", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192194" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10041369": { "compartment": "compartment_70101", "id": "reaction_10041369", "reactome": "R-BTA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041371": { "compartment": "compartment_70101", "id": "reaction_10041371", "reactome": "R-BTA-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192194" ], "products": [ "species_70106", "species_193835", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041373": { "compartment": "compartment_70101", "id": "reaction_10041373", "reactome": "R-BTA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041375": { "compartment": "compartment_70101", "id": "reaction_10041375", "reactome": "R-BTA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041377": { "compartment": "compartment_70101", "id": "reaction_10041377", "reactome": "R-BTA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041208": { "compartment": "compartment_70101", "id": "reaction_10041208", "reactome": "R-BTA-192137", "name": "THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041179": { "compartment": "compartment_5460", "id": "reaction_10041179", "reactome": "R-BTA-192054", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_191968", "species_113600" ], "products": [ "species_113563", "species_192161", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041210": { "compartment": "compartment_70101", "id": "reaction_10041210", "reactome": "R-BTA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041308": { "compartment": "compartment_17951", "id": "reaction_10041308", "reactome": "R-BTA-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192356" ], "products": [ "species_193451", "species_193514" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10041310": { "compartment": "compartment_5460", "id": "reaction_10041310", "reactome": "R-BTA-193393", "name": "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193436", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193387", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041104": { "compartment": "compartment_5460", "id": "reaction_10041104", "reactome": "R-BTA-191999", "name": "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_192078", "species_113529", "species_113600" ], "products": [ "species_192201", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041170": { "compartment": "compartment_70101", "id": "reaction_10041170", "reactome": "R-BTA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041301": { "compartment": "compartment_17951", "id": "reaction_10041301", "reactome": "R-BTA-193369", "name": "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_193442" ], "products": [ "species_113575", "species_193459" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041204": { "compartment": "compartment_70101", "id": "reaction_10041204", "reactome": "R-BTA-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192114" ], "products": [ "species_70106", "species_192136", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041172": { "compartment": "compartment_5460", "id": "reaction_10041172", "reactome": "R-BTA-192042", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192201", "species_113563" ], "products": [ "species_113529", "species_191968", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041111": { "compartment": "compartment_70101", "id": "reaction_10041111", "reactome": "R-BTA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041321": { "compartment": "compartment_70101", "id": "reaction_10041321", "reactome": "R-BTA-193424", "name": "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193505" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041323": { "compartment": "compartment_17951", "id": "reaction_10041323", "reactome": "R-BTA-193452", "name": "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193429" ], "products": [ "species_193442" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041226": { "compartment": "compartment_17951", "id": "reaction_10041226", "reactome": "R-BTA-192335", "name": "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_192316" ], "products": [ "species_113575", "species_192342" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041197": { "compartment": "compartment_70101", "id": "reaction_10041197", "reactome": "R-BTA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041325": { "compartment": "compartment_5460", "id": "reaction_10041325", "reactome": "R-BTA-193460", "name": "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193435", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193440", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041327": { "compartment": "compartment_5460", "id": "reaction_10041327", "reactome": "R-BTA-193497", "name": "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_193387" ], "products": [ "species_193435", "species_113529", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041186": { "compartment": "compartment_17951", "id": "reaction_10041186", "reactome": "R-BTA-192056", "name": "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192308" ], "products": [ "species_192316" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041317": { "compartment": "compartment_70101", "id": "reaction_10041317", "reactome": "R-BTA-193401", "name": "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041319": { "compartment": "compartment_70101", "id": "reaction_10041319", "reactome": "R-BTA-193407", "name": "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_193505", "species_76194" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10085316": { "compartment": "compartment_70101", "id": "reaction_10085316", "reactome": "R-BTA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027095" ] }, "reaction_10076009": { "compartment": "compartment_7660", "id": "reaction_10076009", "reactome": "R-BTA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10069573", "species_10069565" ], "products": [ "species_10076007" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000080567", "ENSBTAT00000010319", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077396": { "compartment": "compartment_7660", "id": "reaction_10077396", "reactome": "R-BTA-6782943", "name": "UV-DDB ubiquitinates XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076069", "species_10036828" ], "products": [ "species_10077087" ], "modifiers": [ [ "species_10076069", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077108": { "compartment": "compartment_7660", "id": "reaction_10077108", "reactome": "R-BTA-5696655", "name": "PARP1 or PARP2 PARylates DDB2 and autoPARylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077089", "species_427523" ], "products": [ "species_427497", "species_10077106" ], "modifiers": [], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740" ] }, "reaction_10076071": { "compartment": "compartment_7660", "id": "reaction_10076071", "reactome": "R-BTA-5691006", "name": "XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076007", "species_10076067", "species_5688114" ], "products": [ "species_10076069", "species_10076065" ], "modifiers": [], "additional_components": [ "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128" ] }, "reaction_10077016": { "compartment": "compartment_7660", "id": "reaction_10077016", "reactome": "R-BTA-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077009" ], "products": [ "species_10036828", "species_10036653" ], "modifiers": [ [ "species_10077013", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q1LZ75", "ENSBTAT00000023078", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000023078", "ENSBTAT00000067380" ] }, "reaction_10036661": { "compartment": "compartment_7660", "id": "reaction_10036661", "reactome": "R-BTA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036657", "species_10036653" ], "products": [ "species_10036659" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046336", "ENSBTAT00000023078", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336" ] }, "reaction_10037517": { "compartment": "compartment_70101", "id": "reaction_10037517", "reactome": "R-BTA-114600", "name": "Fyn/Lyn-mediated phosphorylation of FcR1 gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037504" ], "products": [ "species_29370", "species_10037514" ], "modifiers": [ [ "species_10037504", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420" ] }, "reaction_10049071": { "compartment": "compartment_876", "id": "reaction_10049071", "reactome": "R-BTA-429497", "name": "SLP-76 stimulates PLC gamma 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049069" ], "products": [ "species_10037554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10049395": { "compartment": "compartment_70101", "id": "reaction_10049395", "reactome": "R-BTA-437162", "name": "PI3K alpha, beta, gamma convert PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047493", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10049426": { "compartment": "compartment_70101", "id": "reaction_10049426", "reactome": "R-BTA-442291", "name": "VAV2 is a GEF for Rho/Rac family kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049418" ], "products": [ "species_29420", "species_10049420" ], "modifiers": [ [ "species_10049423", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000086853" ] }, "reaction_10037557": { "compartment": "compartment_70101", "id": "reaction_10037557", "reactome": "R-BTA-114689", "name": "PLC gamma 2-mediated PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10037554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10037588": { "compartment": "compartment_70101", "id": "reaction_10037588", "reactome": "R-BTA-139842", "name": "Binding of Syk tyrosine kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10037514" ], "products": [ "species_10037586" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10050630": { "compartment": "compartment_70101", "id": "reaction_10050630", "reactome": "R-BTA-453183", "name": "p-Y348-SYK dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050628" ], "products": [ "species_10050626", "species_10037514" ], "modifiers": [], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168", "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420" ] }, "reaction_10047475": { "compartment": "compartment_70101", "id": "reaction_10047475", "reactome": "R-BTA-392195", "name": "Gi activation by P2Y purinoceptor 12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047470" ], "products": [ "species_29420", "species_10047472" ], "modifiers": [ [ "species_10047470", "catalyst" ] ], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370" ] }, "reaction_10049039": { "compartment": "compartment_70101", "id": "reaction_10049039", "reactome": "R-BTA-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10036954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10047985": { "compartment": "compartment_70101", "id": "reaction_10047985", "reactome": "R-BTA-418662", "name": "Src activation following P2Y purinoceptor activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040957" ], "products": [ "species_10047983" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000011767" ] }, "reaction_10037201": { "compartment": "compartment_7660", "id": "reaction_10037201", "reactome": "R-BTA-112435", "name": "Formation of Elongin BC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037197", "species_10037193" ], "products": [ "species_10037199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026036", "ENSBTAT00000078734", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036" ] }, "reaction_10037185": { "compartment": "compartment_7660", "id": "reaction_10037185", "reactome": "R-BTA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037181", "species_10037177" ], "products": [ "species_10037183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027214", "ENSBTAT00000073946", "A6QQT5", "ENSBTAT00000073946", "E1BNP8", "ENSBTAT00000027214" ] }, "reaction_10037187": { "compartment": "compartment_7660", "id": "reaction_10037187", "reactome": "R-BTA-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037108", "species_10037098" ], "products": [ "species_10037110" ], "modifiers": [], "additional_components": [ "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231", "ENSBTAT00000006162", "Q5EAB2", "ENSBTAT00000006162", "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231" ] }, "reaction_10037189": { "compartment": "compartment_7660", "id": "reaction_10037189", "reactome": "R-BTA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037135", "species_10037130" ], "products": [ "species_10037137" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070366", "ENSBTAT00000071171", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366" ] }, "reaction_10037207": { "compartment": "compartment_7660", "id": "reaction_10037207", "reactome": "R-BTA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037173" ], "products": [ "species_10037173" ], "modifiers": [], "additional_components": [ "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006" ] }, "reaction_10081897": { "compartment": "compartment_70101", "id": "reaction_10081897", "reactome": "R-BTA-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081893" ], "products": [ "species_10081895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086118", "ENSBTAT00000086118" ] }, "reaction_10037264": { "compartment": "compartment_17906", "id": "reaction_10037264", "reactome": "R-BTA-114307", "name": "Release of SMAC (DIABLO) from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037260" ], "products": [ "species_10037262" ], "modifiers": [ [ "species_10037235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005496", "ENSBTAT00000005496", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10091186": { "compartment": "compartment_70101", "id": "reaction_10091186", "reactome": "R-BTA-9627106", "name": "SMAC (DIABLO) forms dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037262" ], "products": [ "species_10037285" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005496", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10049241": { "compartment": "compartment_876", "id": "reaction_10049241", "reactome": "R-BTA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049243": { "compartment": "compartment_876", "id": "reaction_10049243", "reactome": "R-BTA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049262": { "compartment": "compartment_876", "id": "reaction_10049262", "reactome": "R-BTA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049259", "catalyst" ] ], "additional_components": [ "O77750", "ENSBTAT00000082069" ] }, "reaction_10049253": { "compartment": "compartment_876", "id": "reaction_10049253", "reactome": "R-BTA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049250", "catalyst" ] ], "additional_components": [ "P79099", "ENSBTAT00000011024" ] }, "reaction_10049271": { "compartment": "compartment_876", "id": "reaction_10049271", "reactome": "R-BTA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10049268", "catalyst" ] ], "additional_components": [ "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051145": { "compartment": "compartment_876", "id": "reaction_10051145", "reactome": "R-BTA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051148": { "compartment": "compartment_876", "id": "reaction_10051148", "reactome": "R-BTA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051150": { "compartment": "compartment_876", "id": "reaction_10051150", "reactome": "R-BTA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051136": { "compartment": "compartment_876", "id": "reaction_10051136", "reactome": "R-BTA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10051141": { "compartment": "compartment_876", "id": "reaction_10051141", "reactome": "R-BTA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051143": { "compartment": "compartment_876", "id": "reaction_10051143", "reactome": "R-BTA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10041050": { "compartment": "compartment_70101", "id": "reaction_10041050", "reactome": "R-BTA-191784", "name": "snRNA Cap hypermethylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041043" ], "products": [ "species_10041031" ], "modifiers": [ [ "species_10041047", "catalyst" ] ], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:2274", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000007749" ] }, "reaction_10041039": { "compartment": "compartment_70101", "id": "reaction_10041039", "reactome": "R-BTA-191763", "name": "snRNP:Snurportin complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041031", "species_10041035" ], "products": [ "species_10041037" ], "modifiers": [], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000076267", "Q2TBK8", "ENSBTAT00000076267", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604" ] }, "reaction_10039916": { "compartment": "compartment_17957", "id": "reaction_10039916", "reactome": "R-BTA-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174932", "species_174384" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "species_159154", "CHEBI:17688", "CHEBI:63860", "CHEBI:32663", "ENSBTAT00000076879" ] }, "reaction_10076785": { "compartment": "compartment_5460", "id": "reaction_10076785", "reactome": "R-BTA-5694563", "name": "ABHD10 hydrolyses MPAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694574", "species_113521" ], "products": [ "species_5694569", "species_5694565" ], "modifiers": [ [ "species_10076782", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006038" ] }, "reaction_10038336": { "compartment": "compartment_17957", "id": "reaction_10038336", "reactome": "R-BTA-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_159149", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10038338": { "compartment": "compartment_17957", "id": "reaction_10038338", "reactome": "R-BTA-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10039749": { "compartment": "compartment_70101", "id": "reaction_10039749", "reactome": "R-BTA-173597", "name": "UDP-glucose is oxidised to UDP-glucuronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410", "species_29360" ], "products": [ "species_70106", "species_158601", "species_73473" ], "modifiers": [ [ "species_10039746", "catalyst" ] ], "additional_components": [ "P12378", "ENSBTAT00000019302" ] }, "reaction_10040682": { "compartment": "compartment_5460", "id": "reaction_10040682", "reactome": "R-BTA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10040679", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "A0A452DI36", "ENSBTAT00000005380" ] }, "reaction_10040654": { "compartment": "compartment_17927", "id": "reaction_10040654", "reactome": "R-BTA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10040651", "catalyst" ] ], "additional_components": [ "E1BKY9", "ENSBTAT00000005398" ] }, "reaction_10040688": { "compartment": "compartment_70101", "id": "reaction_10040688", "reactome": "R-BTA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10040669" ], "products": [ "species_10040686", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_190173" ] }, "reaction_10040672": { "compartment": "compartment_70101", "id": "reaction_10040672", "reactome": "R-BTA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10040669", "catalyst" ] ], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315" ] }, "reaction_10066416": { "compartment": "compartment_5460", "id": "reaction_10066416", "reactome": "R-BTA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10066413", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020336" ] }, "reaction_10040645": { "compartment": "compartment_70101", "id": "reaction_10040645", "reactome": "R-BTA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10040642", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q2KIN5", "ENSBTAT00000007052" ] }, "reaction_10040663": { "compartment": "compartment_17927", "id": "reaction_10040663", "reactome": "R-BTA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10040660", "catalyst" ] ], "additional_components": [ "P56602", "ENSBTAT00000061124", "species_113596" ] }, "reaction_10038380": { "compartment": "compartment_5460", "id": "reaction_10038380", "reactome": "R-BTA-159567", "name": "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159559" ], "products": [ "species_159448", "species_159450", "species_159557" ], "modifiers": [ [ "species_10038377", "catalyst" ] ], "additional_components": [ "A7MBE6", "ENSBTAT00000025874" ] }, "reaction_10038382": { "compartment": "compartment_5460", "id": "reaction_10038382", "reactome": "R-BTA-159574", "name": "salicylate-CoA + glycine => salicyluric acid + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159557" ], "products": [ "species_29374", "species_159572" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10083864": { "compartment": "compartment_984", "id": "reaction_10083864", "reactome": "R-BTA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083852": { "compartment": "compartment_984", "id": "reaction_10083852", "reactome": "R-BTA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10083849", "catalyst" ] ], "additional_components": [ "CHEBI:16039", "species_29438", "species_29494", "species_110614", "species_113592", "species_2509811", "species_29370", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "G3MZH7", "ENSBTAT00000063714" ] }, "reaction_10083873": { "compartment": "compartment_17963", "id": "reaction_10083873", "reactome": "R-BTA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_727810", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083889": { "compartment": "compartment_984", "id": "reaction_10083889", "reactome": "R-BTA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10083886", "catalyst" ] ], "additional_components": [ "species_2509811", "species_205687", "species_29420", "species_110094", "species_109402", "species_2509792", "species_727810", "species_113578", "Q2KJI4", "ENSBTAT00000081265", "species_29926", "species_74016" ] }, "reaction_10083861": { "compartment": "compartment_984", "id": "reaction_10083861", "reactome": "R-BTA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083876": { "compartment": "compartment_17963", "id": "reaction_10083876", "reactome": "R-BTA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110614", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083926": { "compartment": "compartment_528865", "id": "reaction_10083926", "reactome": "R-BTA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10083923", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_110094", "species_205687", "species_29420", "species_74016", "G3MYV7", "ENSBTAT00000062934" ] }, "reaction_10066684": { "compartment": "compartment_7660", "id": "reaction_10066684", "reactome": "R-BTA-3215310", "name": "USP7 deubiquitinates TP53 and counteracts MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066675" ], "products": [ "species_10066677", "species_10036828" ], "modifiers": [ [ "species_10066681", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000007177" ] }, "reaction_10081541": { "compartment": "compartment_7660", "id": "reaction_10081541", "reactome": "R-BTA-6804441", "name": "RNF34 or RFFL ubiquitinates phosphorylated TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10036828" ], "products": [ "species_10081534" ], "modifiers": [ [ "species_10081538", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "ENSBTAT00000083405" ] }, "reaction_10066737": { "compartment": "compartment_7660", "id": "reaction_10066737", "reactome": "R-BTA-3222116", "name": "L3MBTL1 binds TP53 monomethylated on K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066733", "species_10066728" ], "products": [ "species_10066735" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000069634", "A0A3Q1M5Y5", "ENSBTAT00000069634", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081877": { "compartment": "compartment_7660", "id": "reaction_10081877", "reactome": "R-BTA-6805730", "name": "SETD9 methylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10033524" ], "products": [ "species_77502", "species_10081870" ], "modifiers": [ [ "species_10081874", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000052840" ] }, "reaction_10066724": { "compartment": "compartment_7660", "id": "reaction_10066724", "reactome": "R-BTA-3222093", "name": "BRD7 binds TP53 and EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066720", "species_10053052" ], "products": [ "species_10066722" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000067101", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10072550": { "compartment": "compartment_7660", "id": "reaction_10072550", "reactome": "R-BTA-5628871", "name": "BRD7 promotes EP300-mediated acetylation of TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066722", "species_113560" ], "products": [ "species_2485002", "species_10072547" ], "modifiers": [ [ "species_10066722", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "A6QLF6", "ENSBTAT00000067101", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10080811": { "compartment": "compartment_7660", "id": "reaction_10080811", "reactome": "R-BTA-6799777", "name": "TP53 family members bind PPP1R13B or TP53BP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080807", "species_10078666" ], "products": [ "species_10080809" ], "modifiers": [], "additional_components": [ "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457" ] }, "reaction_10081530": { "compartment": "compartment_7660", "id": "reaction_10081530", "reactome": "R-BTA-6804425", "name": "TP53 binds POU4F2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081526", "species_10033524" ], "products": [ "species_10081528" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007421", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BLU8", "ENSBTAT00000007421" ] }, "reaction_10080797": { "compartment": "compartment_7660", "id": "reaction_10080797", "reactome": "R-BTA-6799761", "name": "TP53 binds PPP1R13L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078666", "species_10080793" ], "products": [ "species_10080795" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "ENSBTAT00000070207", "A0A3Q1M2S9", "ENSBTAT00000070207", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066764": { "compartment": "compartment_7660", "id": "reaction_10066764", "reactome": "R-BTA-3222259", "name": "PHF20 binds TP53 dimethylated on K370 and K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066754", "species_10066760" ], "products": [ "species_10066762" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BMS9", "ENSBTAT00000007321" ] }, "reaction_10081889": { "compartment": "compartment_7660", "id": "reaction_10081889", "reactome": "R-BTA-6805792", "name": "p-S291-PHF20 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081885" ], "products": [ "species_10081887" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "ENSBTAT00000007321" ] }, "reaction_10081522": { "compartment": "compartment_7660", "id": "reaction_10081522", "reactome": "R-BTA-6804402", "name": "TP53 binds POU4F1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081518" ], "products": [ "species_10081520" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000077824", "A0A3Q1MTW2", "ENSBTAT00000077824", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078474": { "compartment": "compartment_7660", "id": "reaction_10078474", "reactome": "R-BTA-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078470", "species_10037102" ], "products": [ "species_10078472" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002003", "ENSBTAT00000063128", "G3N172", "ENSBTAT00000063128", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10072571": { "compartment": "compartment_70101", "id": "reaction_10072571", "reactome": "R-BTA-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072563", "species_29408" ], "products": [ "species_29356", "species_10072568" ], "modifiers": [ [ "species_10072563", "catalyst" ] ], "additional_components": [ "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751" ] }, "reaction_10072557": { "compartment": "compartment_70101", "id": "reaction_10072557", "reactome": "R-BTA-5628905", "name": "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30533" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10072554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022146" ] }, "reaction_10072591": { "compartment": "compartment_70101", "id": "reaction_10072591", "reactome": "R-BTA-5631903", "name": "SESN1,2,3 bind overoxidized PRDX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072587", "species_10072568" ], "products": [ "species_10072589" ], "modifiers": [], "additional_components": [ "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532" ] }, "reaction_10072595": { "compartment": "compartment_70101", "id": "reaction_10072595", "reactome": "R-BTA-5631941", "name": "SESN1,2,3 bind AMPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046570", "species_10072587" ], "products": [ "species_10072593" ], "modifiers": [], "additional_components": [ "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10072614": { "compartment": "compartment_70101", "id": "reaction_10072614", "reactome": "R-BTA-5632738", "name": "DDIT4 binds 14-3-3 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10072610" ], "products": [ "species_10072612" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000000187", "Q08E62", "ENSBTAT00000000187", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10053210": { "compartment": "compartment_876", "id": "reaction_10053210", "reactome": "R-BTA-937311", "name": "ATP4A/12A:ATP4B exchanges K+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_70106", "species_113592" ], "products": [ "species_351626", "species_29804", "species_29372", "species_29370" ], "modifiers": [ [ "species_10053207", "catalyst" ] ], "additional_components": [ "F1MXW4", "ENSBTAT00000011569", "A0A3Q1M1C8", "ENSBTAT00000073742", "E1BLX8", "ENSBTAT00000026587" ] }, "reaction_10053258": { "compartment": "compartment_876", "id": "reaction_10053258", "reactome": "R-BTA-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947594" ], "products": [ "species_29372", "species_29370", "species_947588" ], "modifiers": [ [ "species_10053255", "catalyst" ] ], "additional_components": [ "species_1602375", "species_1500646", "species_1500646", "species_1602375", "F1MZ89", "ENSBTAT00000035192", "A0A3Q1MCF3", "ENSBTAT00000082277", "A0A3Q1M082", "ENSBTAT00000075591", "F1N3G6", "ENSBTAT00000021914" ] }, "reaction_10076172": { "compartment": "compartment_70101", "id": "reaction_10076172", "reactome": "R-BTA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10076169", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009383" ] }, "reaction_10076179": { "compartment": "compartment_70101", "id": "reaction_10076179", "reactome": "R-BTA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10076176", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010946" ] }, "reaction_10053143": { "compartment": "compartment_20699", "id": "reaction_10053143", "reactome": "R-BTA-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_74016" ], "products": [ "species_29372", "species_29370", "species_167012" ], "modifiers": [ [ "species_10053140", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LYD6", "ENSBTAT00000086525" ] }, "reaction_10071254": { "compartment": "compartment_70101", "id": "reaction_10071254", "reactome": "R-BTA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10071251", "catalyst" ] ], "additional_components": [ "F1N272", "ENSBTAT00000021694", "A0A3Q1M0A4", "ENSBTAT00000077002" ] }, "reaction_10057787": { "compartment": "compartment_5460", "id": "reaction_10057787", "reactome": "R-BTA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379721", "species_10057762", "species_10057776" ], "products": [ "species_10057778", "species_379697", "species_10057784" ], "modifiers": [ [ "species_10057762", "catalyst" ], [ "species_10057776", "catalyst" ] ], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "CHEBI:33739", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33737", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630" ] }, "reaction_10057792": { "compartment": "compartment_5460", "id": "reaction_10057792", "reactome": "R-BTA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113531", "species_10057790" ], "products": [ "species_10057762" ], "modifiers": [], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648" ] }, "reaction_10086272": { "compartment": "compartment_5460", "id": "reaction_10086272", "reactome": "R-BTA-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086254", "species_10086264" ], "products": [ "species_10086252", "species_10086266" ], "modifiers": [ [ "species_10086270", "catalyst" ] ], "additional_components": [ "A6QLZ6", "ENSBTAT00000017860", "CHEBI:33739", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "ENSBTAT00000017860", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "CHEBI:49883", "ENSBTAT00000044111" ] }, "reaction_10070682": { "compartment": "compartment_70101", "id": "reaction_10070682", "reactome": "R-BTA-5218891", "name": "RIPK1:RIPK3 oligomer binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070678", "species_10067320" ], "products": [ "species_10070680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10072346": { "compartment": "compartment_876", "id": "reaction_10072346", "reactome": "R-BTA-5620975", "name": "MLKL binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067330", "species_5620974" ], "products": [ "species_10072328" ], "modifiers": [ [ "species_10072344", "inhibitor" ], [ "species_10072338", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_179838", "species_1806180", "species_6810412", "species_179838", "species_1806180", "species_6810412", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165", "Q08DN8", "ENSBTAT00000013135", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070684": { "compartment": "compartment_70101", "id": "reaction_10070684", "reactome": "R-BTA-5218905", "name": "RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067318" ], "products": [ "species_10067320" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070689": { "compartment": "compartment_70101", "id": "reaction_10070689", "reactome": "R-BTA-5218906", "name": "RIPK3 phosphorylates MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_29370", "species_10070686" ], "modifiers": [ [ "species_10070680", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070531": { "compartment": "compartment_70101", "id": "reaction_10070531", "reactome": "R-BTA-5213464", "name": "RIPK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070524" ], "products": [ "species_29370", "species_10070526" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070534": { "compartment": "compartment_70101", "id": "reaction_10070534", "reactome": "R-BTA-5213466", "name": "RIPK3 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070526" ], "products": [ "species_10067318", "species_29370" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10061064": { "compartment": "compartment_70101", "id": "reaction_10061064", "reactome": "R-BTA-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061067": { "compartment": "compartment_70101", "id": "reaction_10061067", "reactome": "R-BTA-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629753" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10060986": { "compartment": "compartment_70101", "id": "reaction_10060986", "reactome": "R-BTA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10060509", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022635" ] }, "reaction_10060938": { "compartment": "compartment_70101", "id": "reaction_10060938", "reactome": "R-BTA-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_870330" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061134": { "compartment": "compartment_70101", "id": "reaction_10061134", "reactome": "R-BTA-1855232", "name": "I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629746" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061061": { "compartment": "compartment_70101", "id": "reaction_10061061", "reactome": "R-BTA-1855208", "name": "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629739" ], "products": [ "species_29372", "species_1629753" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061014": { "compartment": "compartment_70101", "id": "reaction_10061014", "reactome": "R-BTA-1855180", "name": "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629769" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10061046": { "compartment": "compartment_70101", "id": "reaction_10061046", "reactome": "R-BTA-1855202", "name": "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629746" ], "products": [ "species_29372", "species_1629731" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10044666": { "compartment": "compartment_876", "id": "reaction_10044666", "reactome": "R-BTA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10044663", "catalyst" ] ], "additional_components": [ "A0A3Q1M833", "ENSBTAT00000085091" ] }, "reaction_10074493": { "compartment": "compartment_70101", "id": "reaction_10074493", "reactome": "R-BTA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10074490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004518" ] }, "reaction_10046707": { "compartment": "compartment_17947", "id": "reaction_10046707", "reactome": "R-BTA-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_382577" ], "products": [ "species_382571", "species_29372", "species_29370" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10058216": { "compartment": "compartment_70101", "id": "reaction_10058216", "reactome": "R-BTA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10058213", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ85", "ENSBTAT00000076899", "E1BNL1", "ENSBTAT00000007685", "F1N4I6", "ENSBTAT00000014417", "F1N3Y6", "ENSBTAT00000026744", "F1MUC1", "ENSBTAT00000013298" ] }, "reaction_10074360": { "compartment": "compartment_984", "id": "reaction_10074360", "reactome": "R-BTA-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429802", "species_113592" ], "products": [ "species_382539", "species_29372", "species_29370" ], "modifiers": [ [ "species_10074357", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070307" ] }, "reaction_10070728": { "compartment": "compartment_70101", "id": "reaction_10070728", "reactome": "R-BTA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10070725", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ87", "ENSBTAT00000070992" ] }, "reaction_10057832": { "compartment": "compartment_17906", "id": "reaction_10057832", "reactome": "R-BTA-1369065", "name": "ABCB6 transports porphyrin from cytosol to mitchondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1369066", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1369027" ], "modifiers": [ [ "species_10057829", "catalyst" ] ], "additional_components": [ "A5D7P7", "ENSBTAT00000027459" ] }, "reaction_10046698": { "compartment": "compartment_70616", "id": "reaction_10046698", "reactome": "R-BTA-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_189444", "species_113521" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10046695", "catalyst" ] ], "additional_components": [ "A0A3Q1MUB7", "ENSBTAT00000085390" ] }, "reaction_10058469": { "compartment": "compartment_876", "id": "reaction_10058469", "reactome": "R-BTA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10058466", "catalyst" ] ], "additional_components": [ "A0A3Q1MB23", "ENSBTAT00000080713", "A0A3Q1LS24", "ENSBTAT00000073046" ] }, "reaction_10070743": { "compartment": "compartment_70101", "id": "reaction_10070743", "reactome": "R-BTA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070739", "species_10034379" ], "products": [ "species_10070741" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070886", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "A0A3Q1NB13", "ENSBTAT00000070886" ] }, "reaction_10088584": { "compartment": "compartment_7660", "id": "reaction_10088584", "reactome": "R-BTA-8954056", "name": "E2F6 binds TFDP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056555" ], "products": [ "species_10088582" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000076561", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088554": { "compartment": "compartment_7660", "id": "reaction_10088554", "reactome": "R-BTA-8953111", "name": "E2F6 binds TFDP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056551" ], "products": [ "species_10088552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000084839", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10089578": { "compartment": "compartment_7660", "id": "reaction_10089578", "reactome": "R-BTA-9007447", "name": "E2F6 forms the PRC1L4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10089554", "species_10089550", "species_10066826", "species_10081545" ], "products": [ "species_10089576" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000013026", "ENSBTAT00000076903", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "ENSBTAT00000085264", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "A6H7C4", "ENSBTAT00000076903", "E1BJL2", "ENSBTAT00000013026", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088564": { "compartment": "compartment_7660", "id": "reaction_10088564", "reactome": "R-BTA-8953115", "name": "E2F6:TFDP1 binds to MGA:MAX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088560", "species_10088552" ], "products": [ "species_10088562" ], "modifiers": [], "additional_components": [ "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10088596": { "compartment": "compartment_7660", "id": "reaction_10088596", "reactome": "R-BTA-8954082", "name": "E2F6 binds the PRC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088592", "species_10088586" ], "products": [ "species_10088594" ], "modifiers": [], "additional_components": [ "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711" ] }, "reaction_10089574": { "compartment": "compartment_7660", "id": "reaction_10089574", "reactome": "R-BTA-9007283", "name": "CBX3 and PRC1.6 associate with E2F6.com-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089570", "species_10089550", "species_10089560" ], "products": [ "species_10089572" ], "modifiers": [], "additional_components": [ "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "ENSBTAT00000076903", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A6H7C4", "ENSBTAT00000076903", "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10091049": { "compartment": "compartment_7660", "id": "reaction_10091049", "reactome": "R-BTA-9617927", "name": "FOXO4 binds ATXN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042669", "species_10075370" ], "products": [ "species_10091047" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091096": { "compartment": "compartment_7660", "id": "reaction_10091096", "reactome": "R-BTA-9620532", "name": "SIRT1,SIRT3 deacetylate FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427523", "species_10091084" ], "products": [ "species_427497", "species_427498", "species_10042665" ], "modifiers": [ [ "species_10091093", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "G5E521", "ENSBTAT00000002648", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10091089": { "compartment": "compartment_7660", "id": "reaction_10091089", "reactome": "R-BTA-9620515", "name": "KAT2B,EP300 acetylate FOXO3 under oxidative stress", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10042665" ], "products": [ "species_2485002", "species_10091084" ], "modifiers": [ [ "species_10091086", "catalyst" ], [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10091184": { "compartment": "compartment_7660", "id": "reaction_10091184", "reactome": "R-BTA-9626928", "name": "CREBBP binds FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10042661" ], "products": [ "species_10091182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10091017": { "compartment": "compartment_7660", "id": "reaction_10091017", "reactome": "R-BTA-9614414", "name": "AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042696" ], "products": [ "species_10091015" ], "modifiers": [], "additional_components": [ "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418", "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091033": { "compartment": "compartment_70101", "id": "reaction_10091033", "reactome": "R-BTA-9614564", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091013", "species_10037662" ], "products": [ "species_10091031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "P63103", "ENSBTAT00000000289", "P63103", "ENSBTAT00000000289", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091023": { "compartment": "compartment_70101", "id": "reaction_10091023", "reactome": "R-BTA-9614423", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091019", "species_10044088" ], "products": [ "species_10091021" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10091029": { "compartment": "compartment_70101", "id": "reaction_10091029", "reactome": "R-BTA-9614562", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091011", "species_10091025" ], "products": [ "species_10091027" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "F1N4K5", "ENSBTAT00000014920" ] }, "reaction_10088872": { "compartment": "compartment_7660", "id": "reaction_10088872", "reactome": "R-BTA-8956659", "name": "ABL1 phosphorylates YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10057280" ], "products": [ "species_113582", "species_10088870" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "ENSBTAT00000080797" ] }, "reaction_10088876": { "compartment": "compartment_7660", "id": "reaction_10088876", "reactome": "R-BTA-8956676", "name": "YAP1 binds TP73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088870", "species_10078664" ], "products": [ "species_10088874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10088887": { "compartment": "compartment_13231", "id": "reaction_10088887", "reactome": "R-BTA-8957241", "name": "TP73 tetramer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088880" ], "products": [ "species_10078664" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643" ] }, "reaction_10086458": { "compartment": "compartment_7660", "id": "reaction_10086458", "reactome": "R-BTA-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086449" ], "products": [ "species_77502", "species_10086455" ], "modifiers": [ [ "species_10086449", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086493": { "compartment": "compartment_7660", "id": "reaction_10086493", "reactome": "R-BTA-8936584", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086477" ], "products": [ "species_77502", "species_10086490" ], "modifiers": [ [ "species_10086477", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086509": { "compartment": "compartment_7660", "id": "reaction_10086509", "reactome": "R-BTA-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086504" ], "products": [ "species_77502", "species_10086506" ], "modifiers": [ [ "species_10086504", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086525": { "compartment": "compartment_7660", "id": "reaction_10086525", "reactome": "R-BTA-8937022", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086520" ], "products": [ "species_77502", "species_10086522" ], "modifiers": [ [ "species_10086520", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086541": { "compartment": "compartment_7660", "id": "reaction_10086541", "reactome": "R-BTA-8937113", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086536" ], "products": [ "species_77502", "species_10086538" ], "modifiers": [ [ "species_10086536", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086502": { "compartment": "compartment_7660", "id": "reaction_10086502", "reactome": "R-BTA-8936608", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086497" ], "products": [ "species_77502", "species_10086499" ], "modifiers": [ [ "species_10086497", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086518": { "compartment": "compartment_7660", "id": "reaction_10086518", "reactome": "R-BTA-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086513" ], "products": [ "species_77502", "species_10086515" ], "modifiers": [ [ "species_10086513", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086534": { "compartment": "compartment_7660", "id": "reaction_10086534", "reactome": "R-BTA-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086529" ], "products": [ "species_77502", "species_10086531" ], "modifiers": [ [ "species_10086529", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086638": { "compartment": "compartment_161320", "id": "reaction_10086638", "reactome": "R-BTA-8938108", "name": "SERPINB13 binds cathepsin L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086634", "species_10063945" ], "products": [ "species_10086636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005068", "ENSBTAT00000036427", "A0A452DK38", "ENSBTAT00000036427", "E1BIP8", "ENSBTAT00000005068" ] }, "reaction_10084922": { "compartment": "compartment_7660", "id": "reaction_10084922", "reactome": "R-BTA-8864595", "name": "TFAP2B homodimer binds YEATS4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084918", "species_10084916" ], "products": [ "species_10084920" ], "modifiers": [], "additional_components": [ "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000002913", "Q32LE1", "ENSBTAT00000002913", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084911": { "compartment": "compartment_70101", "id": "reaction_10084911", "reactome": "R-BTA-8864577", "name": "TFAP2C translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084905" ], "products": [ "species_10066845" ], "modifiers": [ [ "species_10084907", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000002671", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084895": { "compartment": "compartment_7660", "id": "reaction_10084895", "reactome": "R-BTA-8864307", "name": "TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10084879", "species_10053052", "species_10084891" ], "products": [ "species_10084893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000021556", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "E1B8D6", "ENSBTAT00000021556", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10084881": { "compartment": "compartment_7660", "id": "reaction_10084881", "reactome": "R-BTA-8864278", "name": "AP-2 (TFAP2) transcription factors form homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084877" ], "products": [ "species_10084879" ], "modifiers": [], "additional_components": [ "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084935": { "compartment": "compartment_7660", "id": "reaction_10084935", "reactome": "R-BTA-8865265", "name": "TFAP2C homodimer binds MYC and KDM5B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069764", "species_10077310", "species_10066847" ], "products": [ "species_10084933" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028871", "ENSBTAT00000076263", "Q0VC14", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "Q2HJ27", "ENSBTAT00000076263", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10084909": { "compartment": "compartment_70101", "id": "reaction_10084909", "reactome": "R-BTA-8864569", "name": "WWOX binds TFAP2C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10084905" ], "products": [ "species_10084907" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084903": { "compartment": "compartment_7660", "id": "reaction_10084903", "reactome": "R-BTA-8864343", "name": "KCTD1 binds TFAP2 homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084899", "species_10084879" ], "products": [ "species_10084901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068462", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "A0A3Q1MKM9", "ENSBTAT00000068462" ] }, "reaction_10063400": { "compartment": "compartment_7660", "id": "reaction_10063400", "reactome": "R-BTA-2032781", "name": "WWTR1 (TAZ) binds TEAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063396", "species_10063378" ], "products": [ "species_10063398" ], "modifiers": [], "additional_components": [ "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10063390": { "compartment": "compartment_7660", "id": "reaction_10063390", "reactome": "R-BTA-2032775", "name": "YAP1 binds TEAD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057280", "species_10063386" ], "products": [ "species_10063388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000067627", "A0A3Q1N1G2", "ENSBTAT00000067627", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10085761": { "compartment": "compartment_7660", "id": "reaction_10085761", "reactome": "R-BTA-8871265", "name": "YAP1 binds TEAD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063394", "species_10057280" ], "products": [ "species_10085759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074335", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10046681": { "compartment": "compartment_7660", "id": "reaction_10046681", "reactome": "R-BTA-382096", "name": "Formation of NR-NCOR Corepressor Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10045690" ], "products": [ "species_10046679" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10054279": { "compartment": "compartment_7660", "id": "reaction_10054279", "reactome": "R-BTA-975040", "name": "KRAB-ZNF / KAP Interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053367", "species_10054275" ], "products": [ "species_10054277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008424", "Q17R08", "ENSBTAT00000080509", "Q17R08", "ENSBTAT00000080509", "E1BJG5", "ENSBTAT00000008424" ] }, "reaction_10065292": { "compartment": "compartment_876", "id": "reaction_10065292", "reactome": "R-BTA-2327738", "name": "DDR1 binds collagen type I, II, III, IV, V, XI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065286", "species_10065288" ], "products": [ "species_10065290" ], "modifiers": [], "additional_components": [ "E1BBP4", "ENSBTAT00000046062", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "E1BBP4", "ENSBTAT00000046062" ] }, "reaction_10068042": { "compartment": "compartment_70101", "id": "reaction_10068042", "reactome": "R-BTA-3465448", "name": "Caspase-8 and FLIP(L) processing at DISC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068032" ], "products": [ "species_10068038", "species_10068040" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068046": { "compartment": "compartment_876", "id": "reaction_10068046", "reactome": "R-BTA-3465459", "name": "FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10035386" ], "products": [ "species_10068044" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10067891": { "compartment": "compartment_876", "id": "reaction_10067891", "reactome": "R-BTA-3371359", "name": "FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10037981" ], "products": [ "species_10067889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10037985": { "compartment": "compartment_876", "id": "reaction_10037985", "reactome": "R-BTA-141156", "name": "TRAIL-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037981", "species_10035384" ], "products": [ "species_10037983" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10035396": { "compartment": "compartment_876", "id": "reaction_10035396", "reactome": "R-BTA-73945", "name": "FAS-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035386", "species_10035384" ], "products": [ "species_10035390" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000085853" ] }, "reaction_10037991": { "compartment": "compartment_70101", "id": "reaction_10037991", "reactome": "R-BTA-141159", "name": "TNF-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037987", "species_10035384" ], "products": [ "species_10037989" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853" ] }, "reaction_10043049": { "compartment": "compartment_70101", "id": "reaction_10043049", "reactome": "R-BTA-201637", "name": "Caspase-mediated cleavage of plectin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043" ], "products": [ "species_10043047", "species_10043045" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082561", "ENSBTAT00000082561", "ENSBTAT00000082561", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044762": { "compartment": "compartment_70101", "id": "reaction_10044762", "reactome": "R-BTA-350319", "name": "Caspase mediated cleavage of vimentin at IDVD (259)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044758", "species_10044760" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10043021": { "compartment": "compartment_70101", "id": "reaction_10043021", "reactome": "R-BTA-201628", "name": "Caspase-mediated cleavage of vimentin at DSVD (85)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10043018", "species_10043016" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043059": { "compartment": "compartment_70101", "id": "reaction_10043059", "reactome": "R-BTA-201639", "name": "Caspase-mediated cleavage of GAS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043053" ], "products": [ "species_10043057", "species_10043055" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028855", "ENSBTAT00000028855", "ENSBTAT00000028855", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044756": { "compartment": "compartment_70101", "id": "reaction_10044756", "reactome": "R-BTA-350318", "name": "Caspase-mediated cleavage of vimentin at TNLD (429)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044743", "species_10044745" ], "modifiers": [ [ "species_10044753", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044923": { "compartment": "compartment_7660", "id": "reaction_10044923", "reactome": "R-BTA-351936", "name": "Caspase-mediated cleavage of claspin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040063" ], "products": [ "species_10044912", "species_10044910" ], "modifiers": [ [ "species_10044920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074281", "ENSBTAT00000074281", "ENSBTAT00000074281", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044906": { "compartment": "compartment_70101", "id": "reaction_10044906", "reactome": "R-BTA-351901", "name": "Caspase-mediated cleavage of MST3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044900" ], "products": [ "species_10044902", "species_10044904" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747", "ENSBTAT00000075747", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10090573": { "compartment": "compartment_7660", "id": "reaction_10090573", "reactome": "R-BTA-9029680", "name": "Caspase-7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037229" ], "products": [ "species_10044920" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043039": { "compartment": "compartment_70101", "id": "reaction_10043039", "reactome": "R-BTA-201634", "name": "Caspase-mediated cleavage of FADK 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043033" ], "products": [ "species_10043037", "species_10043035" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085237", "ENSBTAT00000085237", "ENSBTAT00000085237", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044896": { "compartment": "compartment_12045", "id": "reaction_10044896", "reactome": "R-BTA-351894", "name": "Caspase mediated cleavage of BAP31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044887" ], "products": [ "species_10044893", "species_10044891", "species_10044889" ], "modifiers": [ [ "species_10044867", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044995": { "compartment": "compartment_7660", "id": "reaction_10044995", "reactome": "R-BTA-352268", "name": "Cleavage of Satb1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044989" ], "products": [ "species_10044993", "species_10044991" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028199", "ENSBTAT00000028199", "ENSBTAT00000028199", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044927": { "compartment": "compartment_13231", "id": "reaction_10044927", "reactome": "R-BTA-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044902" ], "products": [ "species_10044925" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747" ] }, "reaction_10044869": { "compartment": "compartment_70101", "id": "reaction_10044869", "reactome": "R-BTA-351863", "name": "Translocation of active caspase-8 to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037638" ], "products": [ "species_10044867" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037723": { "compartment": "compartment_70101", "id": "reaction_10037723", "reactome": "R-BTA-139918", "name": "Phosphorylation of BIM by JNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037716", "species_113592" ], "products": [ "species_10037718", "species_29370", "species_10037721" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "P61285", "ENSBTAT00000081563", "A0A3Q1NJ55", "ENSBTAT00000078264", "P61285", "ENSBTAT00000081563", "ENSBTAT00000078264", "ENSBTAT00000087439" ] }, "reaction_10037727": { "compartment": "compartment_70101", "id": "reaction_10037727", "reactome": "R-BTA-139919", "name": "Translocation of BIM to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037721" ], "products": [ "species_10037725" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000078264" ] }, "reaction_10037706": { "compartment": "compartment_70101", "id": "reaction_10037706", "reactome": "R-BTA-139909", "name": "Translocation of BMF to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037695" ], "products": [ "species_10037704" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077917", "ENSBTAT00000077917" ] }, "reaction_10037702": { "compartment": "compartment_70101", "id": "reaction_10037702", "reactome": "R-BTA-139908", "name": "Phosphorylation of DLC2 by MAPK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037690" ], "products": [ "species_29370", "species_10037695", "species_10037692" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "Q3MHR3", "ENSBTAT00000006190", "Q05KI3", "ENSBTAT00000077917", "ENSBTAT00000077917", "Q3MHR3", "ENSBTAT00000006190", "ENSBTAT00000087439" ] }, "reaction_10051181": { "compartment": "compartment_17906", "id": "reaction_10051181", "reactome": "R-BTA-508163", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037273", "species_10051177" ], "products": [ "species_10051179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264", "F6R2C4", "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264" ] }, "reaction_10037277": { "compartment": "compartment_17906", "id": "reaction_10037277", "reactome": "R-BTA-114352", "name": "Sequestration of tBID by BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037273" ], "products": [ "species_10037275" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000025701", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10051175": { "compartment": "compartment_17906", "id": "reaction_10051175", "reactome": "R-BTA-508162", "name": "BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051171", "species_10051167" ], "products": [ "species_10051173" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076163", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "Q05KJ0", "ENSBTAT00000076163" ] }, "reaction_10037289": { "compartment": "compartment_70101", "id": "reaction_10037289", "reactome": "R-BTA-114354", "name": "SMAC binds XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037283" ], "products": [ "species_10037287" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091191": { "compartment": "compartment_70101", "id": "reaction_10091191", "reactome": "R-BTA-9627350", "name": "SMAC (DIABLO) binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037281" ], "products": [ "species_10037291" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "ENSBTAT00000067597", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091197": { "compartment": "compartment_70101", "id": "reaction_10091197", "reactome": "R-BTA-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10091193" ], "products": [ "species_10091195" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118" ] }, "reaction_10091188": { "compartment": "compartment_70101", "id": "reaction_10091188", "reactome": "R-BTA-9627107", "name": "XIAP binds CASP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10037229" ], "products": [ "species_10037283" ], "modifiers": [ [ "species_10037285", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10039930": { "compartment": "compartment_70101", "id": "reaction_10039930", "reactome": "R-BTA-175987", "name": "NNMT transfers CH3 from AdoMet to PY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175973", "species_71284" ], "products": [ "species_175979", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10038238": { "compartment": "compartment_70101", "id": "reaction_10038238", "reactome": "R-BTA-158609", "name": "TPMT transfers CH3 from AdoMet to 6MP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158619", "species_71284" ], "products": [ "species_70106", "species_71285", "species_158611" ], "modifiers": [ [ "species_10038235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025698" ] }, "reaction_10076898": { "compartment": "compartment_70101", "id": "reaction_10076898", "reactome": "R-BTA-5696213", "name": "AS3MT transfers CH3 from AdoMet to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696224", "species_71284" ], "products": [ "species_5696211", "species_71285" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10071924": { "compartment": "compartment_70101", "id": "reaction_10071924", "reactome": "R-BTA-5603114", "name": "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10071921", "catalyst" ] ], "additional_components": [ "Q29RI9", "ENSBTAT00000016399", "A0A3Q1MZ37", "ENSBTAT00000075325", "species_29926", "species_74126" ] }, "reaction_10076900": { "compartment": "compartment_70101", "id": "reaction_10076900", "reactome": "R-BTA-5696220", "name": "AS3MT transfers CH3 from AdoMet to arsenite(3-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696216", "species_71284" ], "products": [ "species_71285", "species_5696214" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10035863": { "compartment": "compartment_17960", "id": "reaction_10035863", "reactome": "R-BTA-76386", "name": "CYP1A2 S-demethylates 6MMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76384", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_33153" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10076903": { "compartment": "compartment_70101", "id": "reaction_10076903", "reactome": "R-BTA-5696230", "name": "GSTO1 dimer reduces methylarsonate to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5696214" ], "products": [ "species_29356", "species_5696224", "species_111745" ], "modifiers": [ [ "species_10039980", "catalyst" ] ], "additional_components": [ "E1BJ08", "ENSBTAT00000017435" ] }, "reaction_10037800": { "compartment": "compartment_984", "id": "reaction_10037800", "reactome": "R-BTA-140664", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037795", "catalyst" ], [ "species_10037798", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037852": { "compartment": "compartment_984", "id": "reaction_10037852", "reactome": "R-BTA-140700", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037785", "catalyst" ], [ "species_10037850", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037948": { "compartment": "compartment_876", "id": "reaction_10037948", "reactome": "R-BTA-140870", "name": "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037921" ], "products": [ "species_10037945" ], "modifiers": [ [ "species_10037921", "catalyst" ] ], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037950": { "compartment": "compartment_984", "id": "reaction_10037950", "reactome": "R-BTA-140872", "name": "thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037945" ], "products": [ "species_10037829", "species_9693058" ], "modifiers": [], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037923": { "compartment": "compartment_984", "id": "reaction_10037923", "reactome": "R-BTA-140791", "name": "activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037919", "species_10037577" ], "products": [ "species_10037921" ], "modifiers": [], "additional_components": [ "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10071906": { "compartment": "compartment_876", "id": "reaction_10071906", "reactome": "R-BTA-5602080", "name": "Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037841", "species_10037835" ], "products": [ "species_10037843" ], "modifiers": [], "additional_components": [ "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10090181": { "compartment": "compartment_984", "id": "reaction_10090181", "reactome": "R-BTA-9015111", "name": "Factor Xa inhibitors binds Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037785" ], "products": [ "species_10037850" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037845": { "compartment": "compartment_984", "id": "reaction_10037845", "reactome": "R-BTA-140696", "name": "factor V -> factor Va + factor V activation peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037817" ], "products": [ "species_10037813", "species_10037819" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000023573", "species_74016", "F1N0I3", "ENSBTAT00000023573", "ENSBTAT00000023573", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10037815": { "compartment": "compartment_984", "id": "reaction_10037815", "reactome": "R-BTA-140686", "name": "factor Va + factor Xa -> Va:Xa complex (prothrombinase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037813", "species_10037807" ], "products": [ "species_10037795" ], "modifiers": [], "additional_components": [ "species_74016", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10090183": { "compartment": "compartment_984", "id": "reaction_10090183", "reactome": "R-BTA-9015122", "name": "Factor Xa inhibitors bind Va:Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037795" ], "products": [ "species_10037798" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037927": { "compartment": "compartment_984", "id": "reaction_10037927", "reactome": "R-BTA-140806", "name": "SERPINC1 binds SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037925", "species_9693058" ], "products": [ "species_10037919" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071014", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10055529": { "compartment": "compartment_7660", "id": "reaction_10055529", "reactome": "R-BTA-983218", "name": "RAD51B:RAD51C binds single-stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29868", "species_10055525" ], "products": [ "species_10055527" ], "modifiers": [], "additional_components": [ "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "species_29868" ] }, "reaction_10055995": { "compartment": "compartment_7660", "id": "reaction_10055995", "reactome": "R-BTA-1008200", "name": "NFE2 binds the beta globin locus control region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055991", "species_1008228" ], "products": [ "species_10055993" ], "modifiers": [], "additional_components": [ "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479", "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479" ] }, "reaction_10055933": { "compartment": "compartment_70101", "id": "reaction_10055933", "reactome": "R-BTA-997237", "name": "SH2B proteins bind JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055926", "species_10055929" ], "products": [ "species_10055931" ], "modifiers": [], "additional_components": [ "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236", "ENSBTAT00000015986", "E1BCP6", "ENSBTAT00000015986", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10055870": { "compartment": "compartment_7660", "id": "reaction_10055870", "reactome": "R-BTA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055855", "species_10055866" ], "products": [ "species_10055868" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008198", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F2Z4J7", "ENSBTAT00000008198" ] }, "reaction_10055649": { "compartment": "compartment_7660", "id": "reaction_10055649", "reactome": "R-BTA-983285", "name": "RAD51B binds RAD51C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10055519" ], "products": [ "species_10055525" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000025252", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10055920": { "compartment": "compartment_7660", "id": "reaction_10055920", "reactome": "R-BTA-996755", "name": "ZFPM proteins bind GATA proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055890", "species_10055916" ], "products": [ "species_10055918" ], "modifiers": [], "additional_components": [ "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161" ] }, "reaction_10056002": { "compartment": "compartment_5460", "id": "reaction_10056002", "reactome": "R-BTA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10055999", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022789" ] }, "reaction_10055847": { "compartment": "compartment_17906", "id": "reaction_10055847", "reactome": "R-BTA-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055843" ], "products": [ "species_10055845" ], "modifiers": [], "additional_components": [ "D7GLD0", "ENSBTAT00000080672", "D7GLD0", "ENSBTAT00000080672" ] }, "reaction_10085753": { "compartment": "compartment_876", "id": "reaction_10085753", "reactome": "R-BTA-8870732", "name": "PSGs bind proteoglycans and TGF-beta1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085749", "species_10085701" ], "products": [ "species_10085751" ], "modifiers": [], "additional_components": [ "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125" ] }, "reaction_10043323": { "compartment": "compartment_876", "id": "reaction_10043323", "reactome": "R-BTA-202709", "name": "JAM2 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319" ], "products": [ "species_10043321" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043355": { "compartment": "compartment_876", "id": "reaction_10043355", "reactome": "R-BTA-202717", "name": "Heterodimerization of CEACAMs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043351" ], "products": [ "species_10043353" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069303", "A0A3Q1MQ27", "ENSBTAT00000069303" ] }, "reaction_10043375": { "compartment": "compartment_876", "id": "reaction_10043375", "reactome": "R-BTA-202722", "name": "CD48 binds CD244", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043367", "species_10043371" ], "products": [ "species_10043373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014924", "ENSBTAT00000084280", "A0A3Q1LFU5", "ENSBTAT00000084280", "Q2KHZ6", "ENSBTAT00000014924" ] }, "reaction_10044024": { "compartment": "compartment_70101", "id": "reaction_10044024", "reactome": "R-BTA-210283", "name": "Interaction of PECAM-1 and PLC gamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043197" ], "products": [ "species_10044022" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044030": { "compartment": "compartment_876", "id": "reaction_10044030", "reactome": "R-BTA-210285", "name": "Trans-homophilic interaction of PECAM-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044026" ], "products": [ "species_10044028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044034": { "compartment": "compartment_70101", "id": "reaction_10044034", "reactome": "R-BTA-210290", "name": "Interaction of PECAM-1 and SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043216", "species_10044014" ], "products": [ "species_10044032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077857", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10044039": { "compartment": "compartment_70101", "id": "reaction_10044039", "reactome": "R-BTA-210291", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044028" ], "products": [ "species_10044036", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10043393": { "compartment": "compartment_876", "id": "reaction_10043393", "reactome": "R-BTA-202724", "name": "P-selectin binds P-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043379", "species_10043389" ], "products": [ "species_10043391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029578", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10043363": { "compartment": "compartment_876", "id": "reaction_10043363", "reactome": "R-BTA-202721", "name": "JAM2 binds JAM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319", "species_10043359" ], "products": [ "species_10043361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043347": { "compartment": "compartment_876", "id": "reaction_10043347", "reactome": "R-BTA-202714", "name": "CD58 binds CD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043343", "species_10043339" ], "products": [ "species_10043345" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084844", "ENSBTAT00000022936", "Q148M9", "ENSBTAT00000022936", "F6PZJ9", "ENSBTAT00000084844" ] }, "reaction_10043397": { "compartment": "compartment_876", "id": "reaction_10043397", "reactome": "R-BTA-202731", "name": "JAM3 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043359" ], "products": [ "species_10043395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263" ] }, "reaction_10043335": { "compartment": "compartment_876", "id": "reaction_10043335", "reactome": "R-BTA-202713", "name": "CD84 homodimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043331" ], "products": [ "species_10043333" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053223", "F1N7U9", "ENSBTAT00000053223" ] }, "reaction_10066263": { "compartment": "compartment_876", "id": "reaction_10066263", "reactome": "R-BTA-2870221", "name": "E-selectin binds E-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066259", "species_10043387" ], "products": [ "species_10066261" ], "modifiers": [], "additional_components": [ "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578", "ENSBTAT00000009612", "P98107", "ENSBTAT00000009612", "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10038329": { "compartment": "compartment_984", "id": "reaction_10038329", "reactome": "R-BTA-158893", "name": "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038260", "species_10038324" ], "products": [ "species_10038326" ], "modifiers": [ [ "species_10038324", "catalyst" ] ], "additional_components": [ "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793", "P28800", "ENSBTAT00000027793", "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793" ] }, "reaction_10038285": { "compartment": "compartment_984", "id": "reaction_10038285", "reactome": "R-BTA-158750", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038272" ], "products": [ "species_10038260", "species_10038267" ], "modifiers": [ [ "species_10038272", "catalyst" ], [ "species_10038283", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "P60902", "ENSBTAT00000020150", "P04272", "ENSBTAT00000012655" ] }, "reaction_10038303": { "compartment": "compartment_984", "id": "reaction_10038303", "reactome": "R-BTA-158795", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267", "species_10038296" ], "products": [ "species_10038298" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038270": { "compartment": "compartment_984", "id": "reaction_10038270", "reactome": "R-BTA-158747", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267" ], "products": [ "species_10038248" ], "modifiers": [ [ "species_10038260", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038288": { "compartment": "compartment_984", "id": "reaction_10038288", "reactome": "R-BTA-158756", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038248" ], "products": [ "species_10038254" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038307": { "compartment": "compartment_984", "id": "reaction_10038307", "reactome": "R-BTA-158800", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038296", "species_10038248" ], "products": [ "species_10038305" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038290": { "compartment": "compartment_984", "id": "reaction_10038290", "reactome": "R-BTA-158781", "name": "crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_157771", "species_10038265" ], "products": [ "species_10038267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642" ] }, "reaction_10038292": { "compartment": "compartment_984", "id": "reaction_10038292", "reactome": "R-BTA-158784", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038267" ], "products": [ "species_10038272" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038263": { "compartment": "compartment_984", "id": "reaction_10038263", "reactome": "R-BTA-158744", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038254" ], "products": [ "species_10038260", "species_10038248" ], "modifiers": [ [ "species_10038254", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10057598": { "compartment": "compartment_984", "id": "reaction_10057598", "reactome": "R-BTA-1297333", "name": "Association of Acrosin Heavy and Light Chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057594", "species_10057592" ], "products": [ "species_10057596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "G5E5C6", "ENSBTAT00000013434" ] }, "reaction_10057605": { "compartment": "compartment_984", "id": "reaction_10057605", "reactome": "R-BTA-1297354", "name": "Acrosin Cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057602" ], "products": [ "species_10057594", "species_10057592" ], "modifiers": [ [ "species_10057602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434" ] }, "reaction_10091211": { "compartment": "compartment_7660", "id": "reaction_10091211", "reactome": "R-BTA-9629195", "name": "NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091207", "species_10091201" ], "products": [ "species_10091209" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10091566": { "compartment": "compartment_70101", "id": "reaction_10091566", "reactome": "R-BTA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091562" ], "products": [ "species_10091564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010226", "ENSBTAT00000010226" ] }, "reaction_10035854": { "compartment": "compartment_7660", "id": "reaction_10035854", "reactome": "R-BTA-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10035850" ], "products": [ "species_10035852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016732", "F1MUY9", "ENSBTAT00000016732" ] }, "reaction_10036760": { "compartment": "compartment_7660", "id": "reaction_10036760", "reactome": "R-BTA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036755" ], "products": [ "species_10036757", "species_110242" ], "modifiers": [ [ "species_10036755", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10091240": { "compartment": "compartment_7660", "id": "reaction_10091240", "reactome": "R-BTA-9629492", "name": "NEIL3 cleaves spiroiminodihydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091237" ], "products": [ "species_9629439", "species_10091230" ], "modifiers": [ [ "species_10091237", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036782": { "compartment": "compartment_7660", "id": "reaction_10036782", "reactome": "R-BTA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036777" ], "products": [ "species_5635947", "species_10036779" ], "modifiers": [ [ "species_10036777", "catalyst" ] ], "additional_components": [ "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928" ] }, "reaction_10036798": { "compartment": "compartment_7660", "id": "reaction_10036798", "reactome": "R-BTA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036795" ], "products": [ "species_10036788", "species_110249" ], "modifiers": [ [ "species_10036795", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091233": { "compartment": "compartment_7660", "id": "reaction_10091233", "reactome": "R-BTA-9629470", "name": "NEIL3 cleaves 5-guanidinohydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091226" ], "products": [ "species_10091230", "species_9629218" ], "modifiers": [ [ "species_10091226", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036805": { "compartment": "compartment_7660", "id": "reaction_10036805", "reactome": "R-BTA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036802" ], "products": [ "species_10036788", "species_29850" ], "modifiers": [ [ "species_10036802", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10036791": { "compartment": "compartment_7660", "id": "reaction_10036791", "reactome": "R-BTA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036786" ], "products": [ "species_10036788", "species_30947" ], "modifiers": [ [ "species_10036786", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091222": { "compartment": "compartment_7660", "id": "reaction_10091222", "reactome": "R-BTA-9629216", "name": "NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091209" ], "products": [ "species_10091219", "species_9629218" ], "modifiers": [ [ "species_10091209", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10072876": { "compartment": "compartment_7660", "id": "reaction_10072876", "reactome": "R-BTA-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072868", "species_10072872" ], "products": [ "species_10072874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000131", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10072883": { "compartment": "compartment_7660", "id": "reaction_10072883", "reactome": "R-BTA-5653786", "name": "USP43 deISGylates ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10072874" ], "products": [ "species_10072868", "species_10072880", "species_10072878" ], "modifiers": [ [ "species_10072874", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131", "ENSBTAT00000000131", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10073302": { "compartment": "compartment_7660", "id": "reaction_10073302", "reactome": "R-BTA-5655193", "name": "KIAA0101 double monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073294", "species_10036828" ], "products": [ "species_10073300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054209", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q5E9B2", "ENSBTAT00000054209" ] }, "reaction_10044547": { "compartment": "compartment_984", "id": "reaction_10044547", "reactome": "R-BTA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10044544", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024018" ] }, "reaction_10088982": { "compartment": "compartment_984", "id": "reaction_10088982", "reactome": "R-BTA-8980228", "name": "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088979", "catalyst" ] ], "additional_components": [ "A0A3Q1LR40", "ENSBTAT00000075023" ] }, "reaction_10084509": { "compartment": "compartment_876", "id": "reaction_10084509", "reactome": "R-BTA-8857928", "name": "GPIHBP1 binds HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077472", "species_10077480" ], "products": [ "species_10077482" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071232", "species_1678620", "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232" ] }, "reaction_10077487": { "compartment": "compartment_876", "id": "reaction_10077487", "reactome": "R-BTA-6784676", "name": "PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077482" ], "products": [ "species_10077476", "species_10077472", "species_1678620" ], "modifiers": [ [ "species_10077484", "catalyst" ] ], "additional_components": [ "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232", "ENSBTAT00000017086", "ENSBTAT00000071232", "ENSBTAT00000077745" ] }, "reaction_10077489": { "compartment": "compartment_984", "id": "reaction_10077489", "reactome": "R-BTA-6784861", "name": "HSPG binds LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077478", "species_1678620" ], "products": [ "species_10077480" ], "modifiers": [], "additional_components": [ "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086" ] }, "reaction_10077593": { "compartment": "compartment_7660", "id": "reaction_10077593", "reactome": "R-BTA-6785607", "name": "FANCM binds FAAP24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077506", "species_10077502" ], "products": [ "species_10077508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071085", "ENSBTAT00000065656", "Q2KHY5", "ENSBTAT00000065656", "A0A3Q1MT39", "ENSBTAT00000071085" ] }, "reaction_10077625": { "compartment": "compartment_7660", "id": "reaction_10077625", "reactome": "R-BTA-6785732", "name": "DNA nucleases bind monoubiquitinated ID2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036659", "species_10077619", "species_10077582", "species_10075163", "species_10077609" ], "products": [ "species_10077623" ], "modifiers": [], "additional_components": [ "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "E1BN11", "ENSBTAT00000026896", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "ENSBTAT00000085708", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BN11", "ENSBTAT00000026896", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "A0A3Q1MJE2", "ENSBTAT00000085708" ] }, "reaction_10077591": { "compartment": "compartment_7660", "id": "reaction_10077591", "reactome": "R-BTA-6785361", "name": "Monoubiquitination of FANCD2:FANCI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077569", "species_10036828" ], "products": [ "species_10077588", "species_10077582" ], "modifiers": [ [ "species_10077569", "catalyst" ] ], "additional_components": [ "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467" ] }, "reaction_10035372": { "compartment": "compartment_5460", "id": "reaction_10035372", "reactome": "R-BTA-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10035369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005088" ] }, "reaction_10035363": { "compartment": "compartment_5460", "id": "reaction_10035363", "reactome": "R-BTA-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_73909", "species_29362" ], "products": [ "species_113526", "species_73911" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10049883": { "compartment": "compartment_70101", "id": "reaction_10049883", "reactome": "R-BTA-446322", "name": "PARVA associates with Paxillin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049875" ], "products": [ "species_10049881" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000024101", "F1MFD1", "ENSBTAT00000024101", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10049312": { "compartment": "compartment_70101", "id": "reaction_10049312", "reactome": "R-BTA-432946", "name": "PARVB/Affixin interacts with alpha PIX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049308", "species_10048105" ], "products": [ "species_10049310" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084501", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1M7B6", "ENSBTAT00000084501" ] }, "reaction_10049891": { "compartment": "compartment_70101", "id": "reaction_10049891", "reactome": "R-BTA-446372", "name": "Association of PARVA with TESK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049887" ], "products": [ "species_10049889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000082961", "A0A3Q1MET9", "ENSBTAT00000082961", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10038942": { "compartment": "compartment_7660", "id": "reaction_10038942", "reactome": "R-BTA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10035753" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083979" ] }, "reaction_10036844": { "compartment": "compartment_7660", "id": "reaction_10036844", "reactome": "R-BTA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036840", "species_10036809" ], "products": [ "species_10036842" ], "modifiers": [], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000066497", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10036853": { "compartment": "compartment_7660", "id": "reaction_10036853", "reactome": "R-BTA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10036842" ], "products": [ "species_10036850" ], "modifiers": [ [ "species_10036842", "catalyst" ] ], "additional_components": [ "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073275": { "compartment": "compartment_7660", "id": "reaction_10073275", "reactome": "R-BTA-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073270", "species_29358" ], "products": [ "species_113582", "species_10073272", "species_10036857" ], "modifiers": [ [ "species_10073270", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "A5D979", "ENSBTAT00000008030", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10073290": { "compartment": "compartment_7660", "id": "reaction_10073290", "reactome": "R-BTA-5655170", "name": "RCHY1 monoubiquitinates POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10073277" ], "products": [ "species_10073287", "species_10036867" ], "modifiers": [ [ "species_10073277", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "ENSBTAT00000009461", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036879": { "compartment": "compartment_7660", "id": "reaction_10036879", "reactome": "R-BTA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036863", "species_29604" ], "products": [ "species_10036876", "species_113541" ], "modifiers": [ [ "species_10036863", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073279": { "compartment": "compartment_7660", "id": "reaction_10073279", "reactome": "R-BTA-5655142", "name": "RCHY1 binds POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036867", "species_10036857" ], "products": [ "species_10073277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009461", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036869": { "compartment": "compartment_7660", "id": "reaction_10036869", "reactome": "R-BTA-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036861", "species_10036857" ], "products": [ "species_10036863" ], "modifiers": [ [ "species_10036867", "inhibitor" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000009461" ] }, "reaction_10036886": { "compartment": "compartment_7660", "id": "reaction_10036886", "reactome": "R-BTA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10036876" ], "products": [ "species_10036883", "species_113541" ], "modifiers": [ [ "species_10036876", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073254": { "compartment": "compartment_7660", "id": "reaction_10073254", "reactome": "R-BTA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073250", "species_10036883" ], "products": [ "species_10073252" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008030", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030" ] }, "reaction_10090392": { "compartment": "compartment_70101", "id": "reaction_10090392", "reactome": "R-BTA-9020274", "name": "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9025012" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090394": { "compartment": "compartment_70101", "id": "reaction_10090394", "reactome": "R-BTA-9020275", "name": "ALOX15 oxidises DHA to 17(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024012" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090462": { "compartment": "compartment_70101", "id": "reaction_10090462", "reactome": "R-BTA-9024881", "name": "ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024012" ], "products": [ "species_29364", "species_9024873" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090384": { "compartment": "compartment_70101", "id": "reaction_10090384", "reactome": "R-BTA-9020261", "name": "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024522" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090464": { "compartment": "compartment_70101", "id": "reaction_10090464", "reactome": "R-BTA-9024983", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_29364", "species_9025001" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090458": { "compartment": "compartment_70101", "id": "reaction_10090458", "reactome": "R-BTA-9024766", "name": "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024764", "species_29360" ], "products": [ "species_9024799", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "CHEBI:132797", "CHEBI:132800", "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090390": { "compartment": "compartment_70101", "id": "reaction_10090390", "reactome": "R-BTA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090388": { "compartment": "compartment_70101", "id": "reaction_10090388", "reactome": "R-BTA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10062377": { "compartment": "compartment_984", "id": "reaction_10062377", "reactome": "R-BTA-2002440", "name": "Removal of fibrillar collagen C-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062335" ], "products": [ "species_10058697" ], "modifiers": [ [ "species_10062368", "catalyst" ], [ "species_10062375", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "F1N0X6", "ENSBTAT00000007834", "Q2HJB6", "ENSBTAT00000027347", "F1MKP1", "ENSBTAT00000021330" ] }, "reaction_10061787": { "compartment": "compartment_17957", "id": "reaction_10061787", "reactome": "R-BTA-1980233", "name": "Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_10061734", "species_1650779" ], "products": [ "species_1650769", "species_159751", "species_10061784" ], "modifiers": [ [ "species_10061734", "catalyst" ] ], "additional_components": [ "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067" ] }, "reaction_10060187": { "compartment": "compartment_17957", "id": "reaction_10060187", "reactome": "R-BTA-1614460", "name": "Dimerization of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060183" ], "products": [ "species_10060185" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087626": { "compartment": "compartment_17957", "id": "reaction_10087626", "reactome": "R-BTA-8948228", "name": "COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061921", "species_10061791" ], "products": [ "species_10061923" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10062058": { "compartment": "compartment_17957", "id": "reaction_10062058", "reactome": "R-BTA-1981120", "name": "Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1981137", "species_10061923" ], "products": [ "species_10062055", "species_158602" ], "modifiers": [ [ "species_10061923", "catalyst" ] ], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10087628": { "compartment": "compartment_17957", "id": "reaction_10087628", "reactome": "R-BTA-8948231", "name": "COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062055" ], "products": [ "species_10062053", "species_10061791" ], "modifiers": [], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "ENSBTAT00000050322" ] }, "reaction_10060191": { "compartment": "compartment_17957", "id": "reaction_10060191", "reactome": "R-BTA-1614461", "name": "Tetramerization of procollagen VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060185" ], "products": [ "species_10060189" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10064337": { "compartment": "compartment_17957", "id": "reaction_10064337", "reactome": "R-BTA-2152276", "name": "Secretion of transmembrane collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062852" ], "products": [ "species_10064335" ], "modifiers": [], "additional_components": [ "F1MSJ7", "ENSBTAT00000017548", "F6RND5", "ENSBTAT00000039811", "E1BKJ9", "ENSBTAT00000044319", "F1MSJ7", "ENSBTAT00000017548", "E1BKJ9", "ENSBTAT00000044319", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10062352": { "compartment": "compartment_984", "id": "reaction_10062352", "reactome": "R-BTA-2002428", "name": "Removal of fibrillar collagen N-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062205" ], "products": [ "species_10062335" ], "modifiers": [ [ "species_10062349", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "E1BC50", "ENSBTAT00000061447", "E1BFV4", "ENSBTAT00000028224" ] }, "reaction_10063799": { "compartment": "compartment_17957", "id": "reaction_10063799", "reactome": "R-BTA-2089971", "name": "Secretion of collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063637" ], "products": [ "species_10063797", "species_10062846" ], "modifiers": [], "additional_components": [ "Q2KJH6", "ENSBTAT00000083385", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "A0A3Q1M646", "ENSBTAT00000081723", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052", "P02459", "ENSBTAT00000017505", "F1MSJ7", "ENSBTAT00000017548", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "A0A3Q1M0N0", "ENSBTAT00000072268", "A0A3Q1MQC5", "ENSBTAT00000074238", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1M0N0", "ENSBTAT00000072268", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "ENSBTAT00000083385" ] }, "reaction_10064491": { "compartment": "compartment_70101", "id": "reaction_10064491", "reactome": "R-BTA-2161775", "name": "ALOX12 oxidises LTA4 to LXA4/B4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9032038", "species_29368" ], "products": [ "species_2161856" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:6499", "species_2161759", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10064500": { "compartment": "compartment_70101", "id": "reaction_10064500", "reactome": "R-BTA-2161779", "name": "LXA4 is oxidised to 15k-LXA4 by HPGD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161759", "species_29360" ], "products": [ "species_70106", "species_2142761", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10065691": { "compartment": "compartment_984", "id": "reaction_10065691", "reactome": "R-BTA-2466106", "name": "BGN binds Collagen types I, VI, (IX)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282", "species_10062553" ], "products": [ "species_10065689" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000047242", "P21809", "ENSBTAT00000047242", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10065300": { "compartment": "compartment_984", "id": "reaction_10065300", "reactome": "R-BTA-2327909", "name": "DCN binds collagen I, II, III, VI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065296", "species_10065294" ], "products": [ "species_10065298" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000004562", "P21793", "ENSBTAT00000004562", "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10064953": { "compartment": "compartment_984", "id": "reaction_10064953", "reactome": "R-BTA-2213201", "name": "Formation of collagen fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058703" ], "products": [ "species_10064951" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10064959": { "compartment": "compartment_984", "id": "reaction_10064959", "reactome": "R-BTA-2213207", "name": "Formation of collagen networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064955" ], "products": [ "species_10064957" ], "modifiers": [], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10058705": { "compartment": "compartment_984", "id": "reaction_10058705", "reactome": "R-BTA-1474266", "name": "Formation of collagen fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058697" ], "products": [ "species_10058703" ], "modifiers": [], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10065929": { "compartment": "compartment_984", "id": "reaction_10065929", "reactome": "R-BTA-2559639", "name": "Collagen type IV sulfilimine cross-linking by peroxidasin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_351629" ], "products": [ "species_10065920" ], "modifiers": [ [ "species_10065926", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "CHEBI:15858", "A0A3Q1LMN6", "ENSBTAT00000073028" ] }, "reaction_10035464": { "compartment": "compartment_70101", "id": "reaction_10035464", "reactome": "R-BTA-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_83956" ], "products": [ "species_31633", "species_30064" ], "modifiers": [ [ "species_10035461", "catalyst" ] ], "additional_components": [ "species_29426", "F1MLX9", "ENSBTAT00000015339" ] }, "reaction_10088571": { "compartment": "compartment_70101", "id": "reaction_10088571", "reactome": "R-BTA-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109327", "species_29356" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10088568", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026530" ] }, "reaction_10035453": { "compartment": "compartment_70101", "id": "reaction_10035453", "reactome": "R-BTA-74242", "name": "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500172" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036207": { "compartment": "compartment_984", "id": "reaction_10036207", "reactome": "R-BTA-109278", "name": "NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500101" ], "products": [ "species_500104", "species_109277" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_2509792", "species_76577", "species_113578", "species_109386", "CHEBI:17596", "CHEBI:16750", "species_83909", "CHEBI:17256", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035455": { "compartment": "compartment_70101", "id": "reaction_10035455", "reactome": "R-BTA-74249", "name": "(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500245" ], "products": [ "species_83956", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:16750", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036238": { "compartment": "compartment_70101", "id": "reaction_10036238", "reactome": "R-BTA-109415", "name": "AMP + H2O => adenosine + orthophosphate [NT5C1B]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29372", "species_83909" ], "modifiers": [ [ "species_10036235", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006950" ] }, "reaction_10036256": { "compartment": "compartment_70101", "id": "reaction_10036256", "reactome": "R-BTA-109470", "name": "(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500120", "species_29356" ], "products": [ "species_29372", "species_500118" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "species_2509792", "species_2509805", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "CHEBI:17596", "CHEBI:16750", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10036231": { "compartment": "compartment_70101", "id": "reaction_10036231", "reactome": "R-BTA-109387", "name": "(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500125" ], "products": [ "species_29372", "species_500124" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_76577", "species_2509792", "species_2509805", "species_109386", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "species_83909", "CHEBI:17256", "CHEBI:17596", "CHEBI:16750", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10053044": { "compartment": "compartment_70101", "id": "reaction_10053044", "reactome": "R-BTA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053039", "species_113592" ], "products": [ "species_10053041", "species_29370" ], "modifiers": [ [ "species_10053039", "catalyst" ] ], "additional_components": [ "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10090377": { "compartment": "compartment_70101", "id": "reaction_10090377", "reactome": "R-BTA-9018880", "name": "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9022921" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "species_9023653", "species_9020583", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090440": { "compartment": "compartment_70101", "id": "reaction_10090440", "reactome": "R-BTA-9023968", "name": "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9022660", "species_29360" ], "products": [ "species_9023963", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090396": { "compartment": "compartment_70101", "id": "reaction_10090396", "reactome": "R-BTA-9020610", "name": "ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9020474" ], "products": [ "species_9022679" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090374": { "compartment": "compartment_70101", "id": "reaction_10090374", "reactome": "R-BTA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090379": { "compartment": "compartment_70101", "id": "reaction_10090379", "reactome": "R-BTA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090382": { "compartment": "compartment_70101", "id": "reaction_10090382", "reactome": "R-BTA-9018907", "name": "ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023651", "species_29368" ], "products": [ "species_9023644" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10065866": { "compartment": "compartment_876", "id": "reaction_10065866", "reactome": "R-BTA-2534359", "name": "CatSper Channel Mediated Calcium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10065861", "catalyst" ] ], "additional_components": [ "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065884": { "compartment": "compartment_876", "id": "reaction_10065884", "reactome": "R-BTA-2534378", "name": "Hv1 Mediated H+ Permeability", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1132304" ], "products": [ "species_351626" ], "modifiers": [ [ "species_10065881", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10065886": { "compartment": "compartment_984", "id": "reaction_10065886", "reactome": "R-BTA-2534388", "name": "Progesterone Activation Of CatSper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065863", "species_1449667" ], "products": [ "species_10065861" ], "modifiers": [], "additional_components": [ "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586", "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065875": { "compartment": "compartment_876", "id": "reaction_10065875", "reactome": "R-BTA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10065872", "catalyst" ] ], "additional_components": [ "A0A3S5ZP59", "ENSBTAT00000038859" ] }, "reaction_10076856": { "compartment": "compartment_984", "id": "reaction_10076856", "reactome": "R-BTA-5696131", "name": "AOC1 deaminates Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_390899", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696128" ], "modifiers": [ [ "species_10076853", "catalyst" ] ], "additional_components": [ "Q3MHQ1", "ENSBTAT00000007133", "species_74016", "CHEBI:28694" ] }, "reaction_10077496": { "compartment": "compartment_70101", "id": "reaction_10077496", "reactome": "R-BTA-6784959", "name": "BPHL hydrolyses VACV to ACV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6784964" ], "products": [ "species_29702", "species_561052" ], "modifiers": [ [ "species_10077493", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008368" ] }, "reaction_10076475": { "compartment": "compartment_12045", "id": "reaction_10076475", "reactome": "R-BTA-5694077", "name": "EPHX1 hydrates BaP4,5O to BaP4,5-DHD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694080" ], "products": [ "species_5694091" ], "modifiers": [ [ "species_10076472", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083641" ] }, "reaction_10076863": { "compartment": "compartment_984", "id": "reaction_10076863", "reactome": "R-BTA-5696146", "name": "AOC2 deaminates TYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5696181", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696178" ], "modifiers": [ [ "species_10076860", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042833" ] }, "reaction_10076884": { "compartment": "compartment_984", "id": "reaction_10076884", "reactome": "R-BTA-5696183", "name": "AOC3 deaminates BZAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_352327", "species_5696148" ], "products": [ "species_351626", "species_5696154", "species_2022135", "species_351629" ], "modifiers": [ [ "species_10076881", "catalyst" ] ], "additional_components": [ "Q9TTK6", "ENSBTAT00000081083", "A0A452DHX8", "ENSBTAT00000001383", "Q29437", "ENSBTAT00000081083", "species_74016", "CHEBI:28694" ] }, "reaction_10076375": { "compartment": "compartment_17957", "id": "reaction_10076375", "reactome": "R-BTA-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693702" ], "products": [ "species_156540", "species_5693711", "species_5693712" ], "modifiers": [ [ "species_10076372", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461", "F1MU22", "ENSBTAT00000032343" ] }, "reaction_10086550": { "compartment": "compartment_70101", "id": "reaction_10086550", "reactome": "R-BTA-8937419", "name": "CBR3 reduces DOX to DOXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8937424", "species_29364" ], "products": [ "species_29366", "species_8937418" ], "modifiers": [ [ "species_10086547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024873" ] }, "reaction_10044524": { "compartment": "compartment_17960", "id": "reaction_10044524", "reactome": "R-BTA-217255", "name": "FMO1:FAD N-oxidises TAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_159154" ], "products": [ "species_113519", "species_113564", "species_217269" ], "modifiers": [ [ "species_10044521", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1M207", "ENSBTAT00000079411" ] }, "reaction_10044533": { "compartment": "compartment_17960", "id": "reaction_10044533", "reactome": "R-BTA-217258", "name": "FMO2:FAD:Mg2+ S-oxidises MTZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_217315" ], "products": [ "species_113519", "species_113564", "species_217320" ], "modifiers": [ [ "species_10044530", "catalyst" ] ], "additional_components": [ "species_29926", "species_113596", "G5E540", "ENSBTAT00000003873" ] }, "reaction_10034175": { "compartment": "compartment_70101", "id": "reaction_10034175", "reactome": "R-BTA-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29510", "species_29360" ], "products": [ "species_70106", "species_29416", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10034206": { "compartment": "compartment_70101", "id": "reaction_10034206", "reactome": "R-BTA-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_29510", "species_73473" ], "modifiers": [ [ "species_10034203", "catalyst" ] ], "additional_components": [ "species_29426", "E1BBW9", "ENSBTAT00000020879", "F1MFZ4", "ENSBTAT00000003769", "F1MZN9", "ENSBTAT00000009191", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10050160": { "compartment": "compartment_5460", "id": "reaction_10050160", "reactome": "R-BTA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10050157", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086374" ] }, "reaction_10076144": { "compartment": "compartment_70101", "id": "reaction_10076144", "reactome": "R-BTA-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_5692249", "species_70106", "species_73473" ], "modifiers": [ [ "species_10076141", "catalyst" ] ], "additional_components": [ "Q3ZC42", "ENSBTAT00000021304", "species_29426" ] }, "reaction_10034215": { "compartment": "compartment_5460", "id": "reaction_10034215", "reactome": "R-BTA-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113532", "species_113526", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113539" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10034231": { "compartment": "compartment_70101", "id": "reaction_10034231", "reactome": "R-BTA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10034228", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078990" ] }, "reaction_10075404": { "compartment": "compartment_12045", "id": "reaction_10075404", "reactome": "R-BTA-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5689006" ], "products": [ "species_5689001", "species_5688995" ], "modifiers": [ [ "species_10075401", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015373" ] }, "reaction_10086543": { "compartment": "compartment_7660", "id": "reaction_10086543", "reactome": "R-BTA-8937177", "name": "AHR:TCDD binds ARNT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035973", "species_10035969" ], "products": [ "species_10035975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016391", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10086469": { "compartment": "compartment_70101", "id": "reaction_10086469", "reactome": "R-BTA-8936519", "name": "NQO2:FAD dimer reduces quinones to hydroquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936516", "species_8936520" ], "products": [ "species_8936514", "species_8936507" ], "modifiers": [ [ "species_10086466", "catalyst" ], [ "species_209934", "inhibitor" ], [ "species_1130942", "inhibitor" ] ], "additional_components": [ "Q3SZT2", "ENSBTAT00000072063", "species_113596" ] }, "reaction_10077734": { "compartment": "compartment_70101", "id": "reaction_10077734", "reactome": "R-BTA-6786190", "name": "CMBL hydrolyses OM to OLMS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6786175" ], "products": [ "species_6786194", "species_6786179" ], "modifiers": [ [ "species_10077731", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072469" ] }, "reaction_10041241": { "compartment": "compartment_984", "id": "reaction_10041241", "reactome": "R-BTA-192434", "name": "Digestion of diacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_174675" ], "products": [ "species_6814795", "species_174602" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10088973": { "compartment": "compartment_984", "id": "reaction_10088973", "reactome": "R-BTA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088970", "catalyst" ] ], "additional_components": [] }, "reaction_10041239": { "compartment": "compartment_984", "id": "reaction_10041239", "reactome": "R-BTA-192422", "name": "Digestion of triacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10076274": { "compartment": "compartment_876", "id": "reaction_10076274", "reactome": "R-BTA-5693373", "name": "DDAH1,2 hydrolyses ADMA to DMA and L-Cit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693375" ], "products": [ "species_5693410", "species_29968" ], "modifiers": [ [ "species_10076271", "catalyst" ] ], "additional_components": [ "P56965", "ENSBTAT00000049235", "Q3SX44", "ENSBTAT00000085909" ] }, "reaction_10040617": { "compartment": "compartment_984", "id": "reaction_10040617", "reactome": "R-BTA-189062", "name": "lactose + H2O => D-glucose + D-galactose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188973", "species_109276" ], "products": [ "species_70115", "species_188995" ], "modifiers": [ [ "species_10040614", "catalyst" ] ], "additional_components": [ "E1BK89", "ENSBTAT00000020185" ] }, "reaction_10040872": { "compartment": "compartment_984", "id": "reaction_10040872", "reactome": "R-BTA-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040620": { "compartment": "compartment_984", "id": "reaction_10040620", "reactome": "R-BTA-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_189049", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040608": { "compartment": "compartment_984", "id": "reaction_10040608", "reactome": "R-BTA-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189108" ], "products": [ "species_191103", "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040595": { "compartment": "compartment_984", "id": "reaction_10040595", "reactome": "R-BTA-188979", "name": "Digestion of linear starch (amylose) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189075" ], "products": [ "species_191103", "species_188986" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10040866": { "compartment": "compartment_984", "id": "reaction_10040866", "reactome": "R-BTA-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10073378": { "compartment": "compartment_984", "id": "reaction_10073378", "reactome": "R-BTA-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040629": { "compartment": "compartment_984", "id": "reaction_10040629", "reactome": "R-BTA-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040868": { "compartment": "compartment_984", "id": "reaction_10040868", "reactome": "R-BTA-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040870": { "compartment": "compartment_984", "id": "reaction_10040870", "reactome": "R-BTA-191114", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189071" ], "products": [ "species_191103", "species_188986", "species_189108" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10086435": { "compartment": "compartment_984", "id": "reaction_10086435", "reactome": "R-BTA-8936214", "name": "GUCY2C trimer binds GUCA2A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086431", "species_10086425" ], "products": [ "species_10086433" ], "modifiers": [], "additional_components": [ "F1N5B2", "ENSBTAT00000026286", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "F1N5B2", "ENSBTAT00000026286" ] }, "reaction_10036917": { "compartment": "compartment_7660", "id": "reaction_10036917", "reactome": "R-BTA-111438", "name": "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036044", "species_10036072" ], "products": [ "species_10036911" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10039865": { "compartment": "compartment_70101", "id": "reaction_10039865", "reactome": "R-BTA-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_111707", "species_113592" ], "products": [ "species_29372", "species_174393", "species_29370" ], "modifiers": [ [ "species_10039862", "catalyst" ] ], "additional_components": [ "A0A3Q1MN33", "ENSBTAT00000081594", "Q2T9Y6", "ENSBTAT00000026855" ] }, "reaction_10087515": { "compartment": "compartment_876", "id": "reaction_10087515", "reactome": "R-BTA-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1247892" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10077658": { "compartment": "compartment_70101", "id": "reaction_10077658", "reactome": "R-BTA-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247942", "species_1247904" ], "modifiers": [ [ "species_10077655", "catalyst" ] ], "additional_components": [ "A6H738", "ENSBTAT00000013689", "Q0IIH4", "ENSBTAT00000025922" ] }, "reaction_10057079": { "compartment": "compartment_70101", "id": "reaction_10057079", "reactome": "R-BTA-1247922", "name": "GGCT transforms gGluCys to OPRO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393" ], "products": [ "species_111707", "species_1247942" ], "modifiers": [ [ "species_10057076", "catalyst" ] ], "additional_components": [ "Q32LE4", "ENSBTAT00000014010" ] }, "reaction_10075362": { "compartment": "compartment_17927", "id": "reaction_10075362", "reactome": "R-BTA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10075353" ], "products": [ "species_5688281", "species_10037239", "species_5688340" ], "modifiers": [ [ "species_10075359", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q3ZBQ0", "ENSBTAT00000072664", "species_29426" ] }, "reaction_10075350": { "compartment": "compartment_5460", "id": "reaction_10075350", "reactome": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10075337" ], "products": [ "species_5688337", "species_5688274", "species_10075341" ], "modifiers": [ [ "species_10075347", "catalyst" ] ], "additional_components": [ "A0A3Q1MB37", "ENSBTAT00000078990", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "A0A3Q1MB37", "ENSBTAT00000078990", "G5E521", "ENSBTAT00000002648", "species_29426" ] }, "reaction_10072271": { "compartment": "compartment_20699", "id": "reaction_10072271", "reactome": "R-BTA-5617828", "name": "TRIP11:IFT20 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072269" ], "products": [ "species_10072263", "species_10072267" ], "modifiers": [], "additional_components": [ "A0A3Q1MQ84", "ENSBTAT00000084706", "Q58CS6", "ENSBTAT00000084852", "ENSBTAT00000084852", "ENSBTAT00000084706" ] }, "reaction_10058751": { "compartment": "compartment_70101", "id": "reaction_10058751", "reactome": "R-BTA-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058753": { "compartment": "compartment_876", "id": "reaction_10058753", "reactome": "R-BTA-1475025", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1237009" ], "products": [ "species_351626", "species_425425" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058755": { "compartment": "compartment_70101", "id": "reaction_10058755", "reactome": "R-BTA-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058722": { "compartment": "compartment_876", "id": "reaction_10058722", "reactome": "R-BTA-1475017", "name": "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_425425" ], "products": [ "species_109276", "species_1237009" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058772": { "compartment": "compartment_5460", "id": "reaction_10058772", "reactome": "R-BTA-1475028", "name": "Carbonic anhydrase dehydrates bicarbonate (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29896", "species_113529" ], "products": [ "species_113521", "species_29376" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10058774": { "compartment": "compartment_5460", "id": "reaction_10058774", "reactome": "R-BTA-1475032", "name": "Carbonic anhydrase hydrates carbon dioxide (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_29376" ], "products": [ "species_29896", "species_113529" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10040030": { "compartment": "compartment_17957", "id": "reaction_10040030", "reactome": "R-BTA-176059", "name": "GST trimers transfer GS from GSH to luminal substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158543", "species_176065" ], "products": [ "species_176048" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_38987", "CHEBI:29132", "CHEBI:32639", "CHEBI:2505", "CHEBI:35896", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10067425": { "compartment": "compartment_5460", "id": "reaction_10067425", "reactome": "R-BTA-3301943", "name": "GSTK1 dimer transfers GS from GSH to CDNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1655887", "species_3301954" ], "products": [ "species_3301973", "species_3301969" ], "modifiers": [ [ "species_10067422", "catalyst" ] ], "additional_components": [ "F1MRG0", "ENSBTAT00000012969" ] }, "reaction_10040021": { "compartment": "compartment_70101", "id": "reaction_10040021", "reactome": "R-BTA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10040018", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "species_3301954", "CHEBI:30614", "species_3301969", "CHEBI:32639", "CHEBI:34479", "A0A3Q1LMV5", "ENSBTAT00000084460", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425", "E1BJ08", "ENSBTAT00000017435", "Q2NL00", "ENSBTAT00000007403", "A1A4L7", "ENSBTAT00000021896", "A0A3Q1MEZ2", "ENSBTAT00000075831", "A0A3Q1LSN6", "ENSBTAT00000085178", "E1BED9", "ENSBTAT00000005211", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10076133": { "compartment": "compartment_70101", "id": "reaction_10076133", "reactome": "R-BTA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10040185": { "compartment": "compartment_5460", "id": "reaction_10040185", "reactome": "R-BTA-177157", "name": "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_177153" ], "products": [ "species_159448", "species_159450", "species_177137" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10038316": { "compartment": "compartment_70101", "id": "reaction_10038316", "reactome": "R-BTA-158832", "name": "The acetyl group from acetyl-CoA is transferred to the NAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039918": { "compartment": "compartment_70101", "id": "reaction_10039918", "reactome": "R-BTA-174959", "name": "The acetyl group from acetyl-CoA is transferred to the NAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039921": { "compartment": "compartment_70101", "id": "reaction_10039921", "reactome": "R-BTA-174963", "name": "NAT1 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174969", "species_10038314" ], "products": [ "species_10038311", "species_174960" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:45373", "CHEBI:30753", "species_34889", "CHEBI:27565", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:63845", "CHEBI:16395", "CHEBI:63815", "CHEBI:63817", "ENSBTAT00000048506" ] }, "reaction_10039923": { "compartment": "compartment_70101", "id": "reaction_10039923", "reactome": "R-BTA-174967", "name": "NAT2 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174971", "species_10038314" ], "products": [ "species_10038311", "species_174958" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:6030", "species_76424", "species_34889", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:7207", "CHEBI:32643", "CHEBI:16395", "ENSBTAT00000048506" ] }, "reaction_10071722": { "compartment": "compartment_70101", "id": "reaction_10071722", "reactome": "R-BTA-5423664", "name": "CYP3A4,5 hydroxylates AFB1 to AFQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423660", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071719", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071754": { "compartment": "compartment_984", "id": "reaction_10071754", "reactome": "R-BTA-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "CHEBI:78581", "CHEBI:78587", "CHEBI:78579", "CHEBI:78584", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10038060": { "compartment": "compartment_70101", "id": "reaction_10038060", "reactome": "R-BTA-156526", "name": "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_29356", "species_159211", "species_29366" ], "modifiers": [ [ "species_10038057", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071727": { "compartment": "compartment_70101", "id": "reaction_10071727", "reactome": "R-BTA-5423672", "name": "CYP1A2, 3A4 oxidise AFB1 to AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071724", "catalyst" ] ], "additional_components": [ "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10071729": { "compartment": "compartment_12045", "id": "reaction_10071729", "reactome": "R-BTA-5423678", "name": "CYP1A2 hydroxylates AFB1 to AFM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423629", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10071712": { "compartment": "compartment_70101", "id": "reaction_10071712", "reactome": "R-BTA-5423637", "name": "AKR dimers reduce AFBDHO to AFBDOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423727", "species_70106", "species_29364" ], "products": [ "species_29366", "species_5423729" ], "modifiers": [ [ "species_10071709", "catalyst" ] ], "additional_components": [ "F1MZC0", "ENSBTAT00000016300", "F1N6I4", "ENSBTAT00000038217" ] }, "reaction_10071715": { "compartment": "compartment_70101", "id": "reaction_10071715", "reactome": "R-BTA-5423647", "name": "CYP2A13 oxidises AFM1 to AFM1E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423629", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_5423657", "species_29366" ], "modifiers": [ [ "species_10035869", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065779" ] }, "reaction_10071763": { "compartment": "compartment_70101", "id": "reaction_10071763", "reactome": "R-BTA-5433074", "name": "ACY1:Zn2+ dimer hydrolyses mercapturic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490236", "species_29356" ], "products": [ "species_2022890", "species_5490231" ], "modifiers": [ [ "species_10071760", "catalyst" ] ], "additional_components": [ "CHEBI:78580", "CHEBI:78585", "CHEBI:78583", "CHEBI:78578", "species_29426", "F1MR63", "ENSBTAT00000024787" ] }, "reaction_10071717": { "compartment": "compartment_70101", "id": "reaction_10071717", "reactome": "R-BTA-5423653", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5423723" ], "products": [ "species_5423730" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_5423663", "CHEBI:78581", "CHEBI:78587", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10074761": { "compartment": "compartment_70101", "id": "reaction_10074761", "reactome": "R-BTA-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074753", "species_10074751" ], "products": [ "species_10074755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "ENSBTAT00000016216", "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035720": { "compartment": "compartment_7660", "id": "reaction_10035720", "reactome": "R-BTA-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035716", "species_10035710" ], "products": [ "species_10035718" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035712": { "compartment": "compartment_7660", "id": "reaction_10035712", "reactome": "R-BTA-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035708", "species_10035704" ], "products": [ "species_10035710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "ENSBTAT00000014945", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748" ] }, "reaction_10074759": { "compartment": "compartment_7660", "id": "reaction_10074759", "reactome": "R-BTA-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074755" ], "products": [ "species_10035716", "species_10074757" ], "modifiers": [], "additional_components": [ "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000017598", "ENSBTAT00000016216" ] }, "reaction_10074747": { "compartment": "compartment_7660", "id": "reaction_10074747", "reactome": "R-BTA-5683986", "name": "APBB1 and MAPK8 bind diphosphorylated H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074743", "species_10074733", "species_10039497" ], "products": [ "species_10074745" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069360", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000087439", "A0A3Q1LWJ8", "ENSBTAT00000087439", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1MU04", "ENSBTAT00000069360" ] }, "reaction_10074558": { "compartment": "compartment_7660", "id": "reaction_10074558", "reactome": "R-BTA-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074548" ], "products": [ "species_113582", "species_10074555" ], "modifiers": [ [ "species_10074548", "catalyst" ] ], "additional_components": [ "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10074736": { "compartment": "compartment_7660", "id": "reaction_10074736", "reactome": "R-BTA-5683964", "name": "ATM phosphorylates EYA1-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074724" ], "products": [ "species_113582", "species_10074727" ], "modifiers": [ [ "species_10074733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074020", "ENSBTAT00000074020", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074739": { "compartment": "compartment_7660", "id": "reaction_10074739", "reactome": "R-BTA-5683967", "name": "EYA1-4 dephosphorylates tyrosine Y142 of H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10074733" ], "products": [ "species_113550", "species_10074663" ], "modifiers": [ [ "species_10074727", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000074020" ] }, "reaction_10074677": { "compartment": "compartment_7660", "id": "reaction_10074677", "reactome": "R-BTA-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074674" ], "products": [ "species_113582", "species_10074667" ], "modifiers": [ [ "species_10074674", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074679": { "compartment": "compartment_7660", "id": "reaction_10074679", "reactome": "R-BTA-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069716", "species_10074542" ], "products": [ "species_10074544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002687", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687" ] }, "reaction_10074550": { "compartment": "compartment_7660", "id": "reaction_10074550", "reactome": "R-BTA-5682586", "name": "HERC2 and PIAS4 are recruited to DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069303", "species_10074546", "species_10069553" ], "products": [ "species_10074548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001000", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "ENSBTAT00000018496", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10076329": { "compartment": "compartment_7660", "id": "reaction_10076329", "reactome": "R-BTA-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074663", "species_10076288" ], "products": [ "species_10076290" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10076332": { "compartment": "compartment_7660", "id": "reaction_10076332", "reactome": "R-BTA-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076295", "species_29358" ], "products": [ "species_113582", "species_10074530" ], "modifiers": [ [ "species_10076295", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10076303": { "compartment": "compartment_7660", "id": "reaction_10076303", "reactome": "R-BTA-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076300" ], "products": [ "species_113582", "species_10074733" ], "modifiers": [ [ "species_10076300", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076334": { "compartment": "compartment_7660", "id": "reaction_10076334", "reactome": "R-BTA-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074530", "species_10074715" ], "products": [ "species_10076300" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074670": { "compartment": "compartment_7660", "id": "reaction_10074670", "reactome": "R-BTA-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10074667" ], "products": [ "species_77502", "species_10074542" ], "modifiers": [ [ "species_10074667", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074720": { "compartment": "compartment_7660", "id": "reaction_10074720", "reactome": "R-BTA-5683930", "name": "WICH phosphorylates H2AFX on Y142", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074711" ], "products": [ "species_113582", "species_10074715" ], "modifiers": [ [ "species_10074717", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B6X6", "ENSBTAT00000072070", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10076293": { "compartment": "compartment_7660", "id": "reaction_10076293", "reactome": "R-BTA-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076290" ], "products": [ "species_113582", "species_10074665" ], "modifiers": [ [ "species_10076290", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10075173": { "compartment": "compartment_7660", "id": "reaction_10075173", "reactome": "R-BTA-5686578", "name": "Activated ATM phosphorylates ABL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075167" ], "products": [ "species_113582", "species_10075170" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080797", "ENSBTAT00000080797", "ENSBTAT00000040104" ] }, "reaction_10049230": { "compartment": "compartment_70101", "id": "reaction_10049230", "reactome": "R-BTA-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429926" ], "products": [ "species_430042", "species_429925" ], "modifiers": [ [ "species_10049227", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003732" ] }, "reaction_10049232": { "compartment": "compartment_70101", "id": "reaction_10049232", "reactome": "R-BTA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049219", "species_429974" ], "products": [ "species_10049221" ], "modifiers": [], "additional_components": [ "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566", "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566" ] }, "reaction_10061043": { "compartment": "compartment_17957", "id": "reaction_10061043", "reactome": "R-BTA-1855200", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024002" ], "products": [ "species_113551", "species_2024016" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10060963": { "compartment": "compartment_17957", "id": "reaction_10060963", "reactome": "R-BTA-1855163", "name": "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024008" ], "products": [ "species_113551", "species_2024012" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10061122": { "compartment": "compartment_17957", "id": "reaction_10061122", "reactome": "R-BTA-1855225", "name": "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024018" ], "products": [ "species_113551", "species_2564836" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10036907": { "compartment": "compartment_70101", "id": "reaction_10036907", "reactome": "R-BTA-111285", "name": "Formation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035351" ], "products": [ "species_10036905" ], "modifiers": [ [ "species_113578", "catalyst" ], [ "species_29602", "catalyst" ], [ "species_76577", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035339": { "compartment": "compartment_70101", "id": "reaction_10035339", "reactome": "R-BTA-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_29372", "species_111370", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035354": { "compartment": "compartment_70101", "id": "reaction_10035354", "reactome": "R-BTA-73815", "name": "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_29356", "species_29472" ], "products": [ "species_111294", "species_111292", "species_29404" ], "modifiers": [ [ "species_10035351", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10036909": { "compartment": "compartment_70101", "id": "reaction_10036909", "reactome": "R-BTA-111289", "name": "Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036905" ], "products": [ "species_10035351" ], "modifiers": [ [ "species_73566", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035308": { "compartment": "compartment_70101", "id": "reaction_10035308", "reactome": "R-BTA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10035305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084984" ] }, "reaction_10091727": { "compartment": "compartment_70101", "id": "reaction_10091727", "reactome": "R-BTA-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678719", "species_10035314" ], "products": [ "species_10035317" ], "modifiers": [], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10035342": { "compartment": "compartment_70101", "id": "reaction_10035342", "reactome": "R-BTA-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_111354", "species_111355" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035345": { "compartment": "compartment_70101", "id": "reaction_10035345", "reactome": "R-BTA-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111292", "species_113592", "species_29424" ], "products": [ "species_29372", "species_111338", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035329": { "compartment": "compartment_70101", "id": "reaction_10035329", "reactome": "R-BTA-73805", "name": "CAIR + Aspartate + ATP => SAICAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29448", "species_111395" ], "products": [ "species_29372", "species_29370", "species_111399" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10036928": { "compartment": "compartment_70101", "id": "reaction_10036928", "reactome": "R-BTA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10036925", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "A7MBG0", "ENSBTAT00000047061", "species_29926" ] }, "reaction_10035332": { "compartment": "compartment_70101", "id": "reaction_10035332", "reactome": "R-BTA-73806", "name": "AIR + CO2 => CAIR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111370", "species_113528" ], "products": [ "species_111395" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10035319": { "compartment": "compartment_70101", "id": "reaction_10035319", "reactome": "R-BTA-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29602", "species_29360" ], "products": [ "species_70106", "species_111584", "species_73473" ], "modifiers": [ [ "species_10035314", "catalyst" ], [ "species_111584", "inhibitor" ], [ "species_10035317", "inhibitor" ] ], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10076312": { "compartment": "compartment_7660", "id": "reaction_10076312", "reactome": "R-BTA-5693575", "name": "DNA-PKcs autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076309" ], "products": [ "species_113582", "species_10075286" ], "modifiers": [ [ "species_10076309", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076347": { "compartment": "compartment_7660", "id": "reaction_10076347", "reactome": "R-BTA-5693615", "name": "Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076305", "species_10076345" ], "products": [ "species_10076309" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10075295": { "compartment": "compartment_7660", "id": "reaction_10075295", "reactome": "R-BTA-5687183", "name": "PRKDC phosphorylates DCLRE1C at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075288" ], "products": [ "species_113582", "species_10075292" ], "modifiers": [ [ "species_10075288", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076286": { "compartment": "compartment_7660", "id": "reaction_10076286", "reactome": "R-BTA-5693533", "name": "DCLRE1C (ARTEMIS) processes DNA DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075292" ], "products": [ "species_10076283" ], "modifiers": [ [ "species_10075292", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076327": { "compartment": "compartment_7660", "id": "reaction_10076327", "reactome": "R-BTA-5693578", "name": "TDP1 and TDP2 process unligatable DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076283" ], "products": [ "species_10076314" ], "modifiers": [ [ "species_10076324", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10036649": { "compartment": "compartment_70101", "id": "reaction_10036649", "reactome": "R-BTA-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10036646", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A3Q1LZ00", "ENSBTAT00000077740" ] }, "reaction_10034989": { "compartment": "compartment_70101", "id": "reaction_10034989", "reactome": "R-BTA-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10034986", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A452DII0", "ENSBTAT00000014316" ] }, "reaction_10035020": { "compartment": "compartment_70101", "id": "reaction_10035020", "reactome": "R-BTA-73632", "name": "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_83928" ], "products": [ "species_29370", "species_109366" ], "modifiers": [ [ "species_10035017", "catalyst" ] ], "additional_components": [ "A0A3Q1NEX0", "ENSBTAT00000073714" ] }, "reaction_10035007": { "compartment": "compartment_70101", "id": "reaction_10035007", "reactome": "R-BTA-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500829" ], "products": [ "species_500430", "species_31633" ], "modifiers": [ [ "species_10035004", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "CHEBI:16450", "CHEBI:16704", "species_29426", "A0A3Q1MGS0", "ENSBTAT00000074118" ] }, "reaction_10088624": { "compartment": "compartment_70101", "id": "reaction_10088624", "reactome": "R-BTA-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10088621", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "ENSBTAT00000071389" ] }, "reaction_10034980": { "compartment": "compartment_70101", "id": "reaction_10034980", "reactome": "R-BTA-73598", "name": "(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_113592" ], "products": [ "species_500828", "species_29370" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "species_727810", "species_109378", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035479": { "compartment": "compartment_70101", "id": "reaction_10035479", "reactome": "R-BTA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10036614": { "compartment": "compartment_5460", "id": "reaction_10036614", "reactome": "R-BTA-109759", "name": "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500822" ], "products": [ "species_113581", "species_500823" ], "modifiers": [ [ "species_10036611", "catalyst" ] ], "additional_components": [ "species_83928", "CHEBI:16450", "CHEBI:15698", "species_109366", "species_500742", "species_109378", "ENSBTAT00000064369" ] }, "reaction_10069313": { "compartment": "compartment_984", "id": "reaction_10069313", "reactome": "R-BTA-4084505", "name": "Laminins bind HSPG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693", "species_10069309" ], "products": [ "species_10069311" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022744", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "F1MER7", "ENSBTAT00000022744" ] }, "reaction_10044515": { "compartment": "compartment_984", "id": "reaction_10044515", "reactome": "R-BTA-216048", "name": "Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044511", "species_10044490" ], "products": [ "species_10044513" ], "modifiers": [], "additional_components": [ "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126" ] }, "reaction_10065555": { "compartment": "compartment_984", "id": "reaction_10065555", "reactome": "R-BTA-2426450", "name": "Laminins:Nidogens binds collagen type IV networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_10065551" ], "products": [ "species_10065553" ], "modifiers": [], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10047065": { "compartment": "compartment_17951", "id": "reaction_10047065", "reactome": "R-BTA-390438", "name": "FAR2 reduces PalmCoA to HXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200993" ], "products": [ "species_29366", "species_8848577", "species_76194" ], "modifiers": [ [ "species_10047062", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014725" ] }, "reaction_10083577": { "compartment": "compartment_12045", "id": "reaction_10083577", "reactome": "R-BTA-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_30209" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10083575": { "compartment": "compartment_12045", "id": "reaction_10083575", "reactome": "R-BTA-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_8848499", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10091611": { "compartment": "compartment_70101", "id": "reaction_10091611", "reactome": "R-BTA-9663492", "name": "BIL dissociates from GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091609" ], "products": [ "species_10091607", "species_189386" ], "modifiers": [], "additional_components": [ "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091613": { "compartment": "compartment_70101", "id": "reaction_10091613", "reactome": "R-BTA-9663511", "name": "BIL binds GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091607", "species_189386" ], "products": [ "species_10091609" ], "modifiers": [], "additional_components": [ "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091598": { "compartment": "compartment_70101", "id": "reaction_10091598", "reactome": "R-BTA-9661397", "name": "SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10091605": { "compartment": "compartment_70101", "id": "reaction_10091605", "reactome": "R-BTA-9661799", "name": "SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10091602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10069412": { "compartment": "compartment_876", "id": "reaction_10069412", "reactome": "R-BTA-4088281", "name": "Endorepellin binds KDR (VEGFR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041457", "species_10068872" ], "products": [ "species_10069410" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001038", "ENSBTAT00000022744", "F1MER7", "ENSBTAT00000022744", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10074474": { "compartment": "compartment_12045", "id": "reaction_10074474", "reactome": "R-BTA-5682084", "name": "ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_10074459" ], "products": [ "species_10074467", "species_76194" ], "modifiers": [ [ "species_10074471", "catalyst" ] ], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538", "ENSBTAT00000006197" ] }, "reaction_10074486": { "compartment": "compartment_12045", "id": "reaction_10074486", "reactome": "R-BTA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074467" ], "products": [ "species_10074478" ], "modifiers": [], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538" ] }, "reaction_10076091": { "compartment": "compartment_70101", "id": "reaction_10076091", "reactome": "R-BTA-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10039822" ], "products": [ "species_10076089" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "ENSBTAT00000068449", "F1MYD0", "ENSBTAT00000068449", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10059181": { "compartment": "compartment_70101", "id": "reaction_10059181", "reactome": "R-BTA-1562626", "name": "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_71067", "species_29368" ], "products": [ "species_5691103" ], "modifiers": [ [ "species_10059178", "catalyst" ] ], "additional_components": [ "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "O46415", "ENSBTAT00000009965" ] }, "reaction_10076083": { "compartment": "compartment_70101", "id": "reaction_10076083", "reactome": "R-BTA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076005", "species_10033408" ], "products": [ "species_10076074" ], "modifiers": [ [ "species_10076080", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077304", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000077304", "E1BJ64", "ENSBTAT00000028591", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10052866": { "compartment": "compartment_984", "id": "reaction_10052866", "reactome": "R-BTA-917805", "name": "CYBRD1:Heme reduces Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917828", "species_912516" ], "products": [ "species_435347" ], "modifiers": [ [ "species_10052863", "catalyst" ] ], "additional_components": [ "species_71185", "F1MLZ1", "ENSBTAT00000010387" ] }, "reaction_10052916": { "compartment": "compartment_984", "id": "reaction_10052916", "reactome": "R-BTA-917888", "name": "apoTF binds 2Fe3+ to form holoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_912516", "species_10051000" ], "products": [ "species_10052874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10087646": { "compartment": "compartment_70616", "id": "reaction_10087646", "reactome": "R-BTA-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2889072", "species_8949220" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10087643", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10061116": { "compartment": "compartment_70101", "id": "reaction_10061116", "reactome": "R-BTA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10060956": { "compartment": "compartment_70101", "id": "reaction_10060956", "reactome": "R-BTA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061040": { "compartment": "compartment_70101", "id": "reaction_10061040", "reactome": "R-BTA-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061011": { "compartment": "compartment_70101", "id": "reaction_10061011", "reactome": "R-BTA-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10061008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10060980": { "compartment": "compartment_70101", "id": "reaction_10060980", "reactome": "R-BTA-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10060983": { "compartment": "compartment_70101", "id": "reaction_10060983", "reactome": "R-BTA-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023943" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10060969", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797" ] }, "reaction_10061079": { "compartment": "compartment_70101", "id": "reaction_10061079", "reactome": "R-BTA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061034": { "compartment": "compartment_70101", "id": "reaction_10061034", "reactome": "R-BTA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063018": { "compartment": "compartment_70101", "id": "reaction_10063018", "reactome": "R-BTA-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023974" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061037": { "compartment": "compartment_70101", "id": "reaction_10061037", "reactome": "R-BTA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063020": { "compartment": "compartment_70101", "id": "reaction_10063020", "reactome": "R-BTA-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_29372", "species_2023974" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061024": { "compartment": "compartment_70101", "id": "reaction_10061024", "reactome": "R-BTA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061125": { "compartment": "compartment_70101", "id": "reaction_10061125", "reactome": "R-BTA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061113": { "compartment": "compartment_876", "id": "reaction_10061113", "reactome": "R-BTA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061110", "catalyst" ] ], "additional_components": [ "species_74016", "E1BJE0", "ENSBTAT00000034821", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MTE8", "ENSBTAT00000078103", "A0A3Q1M8P8", "ENSBTAT00000085120" ] }, "reaction_10061084": { "compartment": "compartment_70101", "id": "reaction_10061084", "reactome": "R-BTA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10061081", "catalyst" ] ], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10061006": { "compartment": "compartment_70101", "id": "reaction_10061006", "reactome": "R-BTA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061003", "catalyst" ] ], "additional_components": [ "species_74016", "Q1RML2", "ENSBTAT00000017574", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10060917": { "compartment": "compartment_70101", "id": "reaction_10060917", "reactome": "R-BTA-1855153", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114520" ], "products": [ "species_29370", "species_994170" ], "modifiers": [ [ "species_10060914", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LNH2", "ENSBTAT00000070709", "A0A3Q1MR28", "ENSBTAT00000044622", "F1MN32", "ENSBTAT00000025930", "A4FV33", "ENSBTAT00000002194" ] }, "reaction_10061076": { "compartment": "compartment_12045", "id": "reaction_10061076", "reactome": "R-BTA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10061073", "catalyst" ] ], "additional_components": [ "A0A3Q1LJY0", "ENSBTAT00000074483", "species_74016" ] }, "reaction_10036003": { "compartment": "compartment_7660", "id": "reaction_10036003", "reactome": "R-BTA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034244", "species_10034248" ], "products": [ "species_10034250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011684", "ENSBTAT00000061170", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10084424": { "compartment": "compartment_13977", "id": "reaction_10084424", "reactome": "R-BTA-8856630", "name": "CIDEA:CIDEC binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084420", "species_8866926" ], "products": [ "species_10084422" ], "modifiers": [], "additional_components": [ "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299" ] }, "reaction_10084480": { "compartment": "compartment_12045", "id": "reaction_10084480", "reactome": "R-BTA-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10084476" ], "products": [ "species_10084478" ], "modifiers": [], "additional_components": [ "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "species_549167" ] }, "reaction_10084694": { "compartment": "compartment_70101", "id": "reaction_10084694", "reactome": "R-BTA-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084690", "species_8866926" ], "products": [ "species_10084692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038453", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "Q29RS1", "ENSBTAT00000038453" ] }, "reaction_10083544": { "compartment": "compartment_70101", "id": "reaction_10083544", "reactome": "R-BTA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10083541", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021067" ] }, "reaction_10083547": { "compartment": "compartment_70101", "id": "reaction_10083547", "reactome": "R-BTA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10083541", "catalyst" ], [ "species_10083337", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000021067", "ENSBTAT00000015669" ] }, "reaction_10071388": { "compartment": "compartment_70101", "id": "reaction_10071388", "reactome": "R-BTA-5334794", "name": "FABPs bind LCFAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876730", "species_10071384" ], "products": [ "species_10071386" ], "modifiers": [], "additional_components": [ "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "species_1602366" ] }, "reaction_10035435": { "compartment": "compartment_70101", "id": "reaction_10035435", "reactome": "R-BTA-74213", "name": "Adenine + PRPP => AMP + PPi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10035432", "catalyst" ] ], "additional_components": [ "A0A452DIE3", "ENSBTAT00000000841" ] }, "reaction_10051215": { "compartment": "compartment_70101", "id": "reaction_10051215", "reactome": "R-BTA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10051212", "catalyst" ] ], "additional_components": [ "F1MCZ0", "ENSBTAT00000003519", "F6R1R5", "ENSBTAT00000020904" ] }, "reaction_10036001": { "compartment": "compartment_70101", "id": "reaction_10036001", "reactome": "R-BTA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10035998", "catalyst" ] ], "additional_components": [ "E1BA23", "ENSBTAT00000021018", "F1MLX6", "ENSBTAT00000015348", "A0A3Q1M723", "ENSBTAT00000080896" ] }, "reaction_10035426": { "compartment": "compartment_5460", "id": "reaction_10035426", "reactome": "R-BTA-74207", "name": "dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500224" ], "products": [ "species_113581", "species_500222" ], "modifiers": [ [ "species_10035423", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "CHEBI:28997", "species_109327", "species_109386", "species_2509805", "Q2KIN2", "ENSBTAT00000047239" ] }, "reaction_10036306": { "compartment": "compartment_70101", "id": "reaction_10036306", "reactome": "R-BTA-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_500088", "species_29370" ], "modifiers": [ [ "species_10036303", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "A0A3Q1MB39", "ENSBTAT00000071820", "species_29926" ] }, "reaction_10036308": { "compartment": "compartment_70101", "id": "reaction_10036308", "reactome": "R-BTA-109671", "name": "deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500201", "species_113592" ], "products": [ "species_29370", "species_500199" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "species_109386", "species_109327", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035444": { "compartment": "compartment_70101", "id": "reaction_10035444", "reactome": "R-BTA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10035441", "catalyst" ] ], "additional_components": [ "species_83956", "species_29850", "species_2509792", "species_113578", "Q3SZ18", "ENSBTAT00000019547", "species_29926" ] }, "reaction_10050378": { "compartment": "compartment_7660", "id": "reaction_10050378", "reactome": "R-BTA-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050287" ], "products": [ "species_113582", "species_10050298" ], "modifiers": [ [ "species_10050375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000805", "ENSBTAT00000000805", "ENSBTAT00000078659" ] }, "reaction_10050368": { "compartment": "compartment_7660", "id": "reaction_10050368", "reactome": "R-BTA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050287", "species_450613" ], "products": [ "species_10050289" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050400": { "compartment": "compartment_7660", "id": "reaction_10050400", "reactome": "R-BTA-450595", "name": "HuR:mRNA complex translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050304" ], "products": [ "species_10050398", "species_10050382" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000000141" ] }, "reaction_10051219": { "compartment": "compartment_7660", "id": "reaction_10051219", "reactome": "R-BTA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050293", "species_450605" ], "products": [ "species_10050295" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050306": { "compartment": "compartment_7660", "id": "reaction_10050306", "reactome": "R-BTA-450387", "name": "HuR binds the CRM1 nuclear export machinery", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050261", "species_10050273", "species_10050302", "species_10050269", "species_10050283", "species_10050265" ], "products": [ "species_10050304" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000141", "ENSBTAT00000029190", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000016410", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10051221": { "compartment": "compartment_7660", "id": "reaction_10051221", "reactome": "R-BTA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050298", "species_517622" ], "products": [ "species_10050300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10051066": { "compartment": "compartment_70101", "id": "reaction_10051066", "reactome": "R-BTA-482788", "name": "p-S54,92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050363" ], "products": [ "species_10051064" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050366": { "compartment": "compartment_70101", "id": "reaction_10050366", "reactome": "R-BTA-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050357", "species_113592" ], "products": [ "species_29370", "species_10050363" ], "modifiers": [ [ "species_10040551", "catalyst" ] ], "additional_components": [ "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "ENSBTAT00000084476" ] }, "reaction_10050318": { "compartment": "compartment_70101", "id": "reaction_10050318", "reactome": "R-BTA-450406", "name": "p-S92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050314" ], "products": [ "species_10050316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050373": { "compartment": "compartment_70101", "id": "reaction_10050373", "reactome": "R-BTA-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450523", "species_10050355" ], "products": [ "species_10050357" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778" ] }, "reaction_10050408": { "compartment": "compartment_70101", "id": "reaction_10050408", "reactome": "R-BTA-450620", "name": "p-S193-KSRP binds 14-3-3zeta in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050402", "species_10050371" ], "products": [ "species_10050406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "ENSBTAT00000070369", "P63103", "ENSBTAT00000000289", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10050380": { "compartment": "compartment_70101", "id": "reaction_10050380", "reactome": "R-BTA-450592", "name": "KSRP binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050322", "species_450386" ], "products": [ "species_10050324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070369", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10049346": { "compartment": "compartment_876", "id": "reaction_10049346", "reactome": "R-BTA-434381", "name": "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400452" ], "products": [ "species_3632881" ], "modifiers": [ [ "species_10049343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080828" ] }, "reaction_10049351": { "compartment": "compartment_17906", "id": "reaction_10049351", "reactome": "R-BTA-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_1132084", "species_200993", "species_76577" ], "modifiers": [ [ "species_10049348", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022939" ] }, "reaction_10044634": { "compartment": "compartment_70101", "id": "reaction_10044634", "reactome": "R-BTA-265682", "name": "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044615", "species_113592" ], "products": [ "species_6790050", "species_10044619" ], "modifiers": [ [ "species_10044615", "catalyst" ], [ "species_70113", "catalyst" ], [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ], [ "species_158417", "inhibitor" ] ], "additional_components": [ "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_29926", "species_29370", "A2VDS4", "ENSBTAT00000021523", "species_113592", "E1BKR6", "ENSBTAT00000046676", "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10047765": { "compartment": "compartment_876", "id": "reaction_10047765", "reactome": "R-BTA-400071", "name": "Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10034971": { "compartment": "compartment_70101", "id": "reaction_10034971", "reactome": "R-BTA-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109378" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10034968", "catalyst" ] ], "additional_components": [ "A6QQC3", "ENSBTAT00000083533" ] }, "reaction_10035038": { "compartment": "compartment_70101", "id": "reaction_10035038", "reactome": "R-BTA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10035035", "catalyst" ] ], "additional_components": [ "A0JNE9", "ENSBTAT00000068403" ] }, "reaction_10035698": { "compartment": "compartment_70101", "id": "reaction_10035698", "reactome": "R-BTA-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500006" ], "products": [ "species_500009", "species_113592" ], "modifiers": [ [ "species_10034909", "catalyst" ] ], "additional_components": [ "species_205687", "CHEBI:28846", "species_110094", "species_727810", "species_109378", "species_109402", "ENSBTAT00000026582" ] }, "reaction_10035029": { "compartment": "compartment_70101", "id": "reaction_10035029", "reactome": "R-BTA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10035026", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "A0A3Q1N7A8", "ENSBTAT00000069715" ] }, "reaction_10036692": { "compartment": "compartment_70101", "id": "reaction_10036692", "reactome": "R-BTA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10036689", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023406" ] }, "reaction_10034998": { "compartment": "compartment_70101", "id": "reaction_10034998", "reactome": "R-BTA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10034995", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NID0", "ENSBTAT00000077973" ] }, "reaction_10036683": { "compartment": "compartment_70101", "id": "reaction_10036683", "reactome": "R-BTA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_727810", "species_109378", "species_109386", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10036938": { "compartment": "compartment_70101", "id": "reaction_10036938", "reactome": "R-BTA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036935", "species_29450" ], "products": [ "species_10036932", "species_111745" ], "modifiers": [ [ "species_10036935", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001575", "ENSBTAT00000001575", "ENSBTAT00000001575" ] }, "reaction_10036685": { "compartment": "compartment_70101", "id": "reaction_10036685", "reactome": "R-BTA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_76577", "species_727810", "species_109378", "species_109386", "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10051075": { "compartment": "compartment_5460", "id": "reaction_10051075", "reactome": "R-BTA-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_482803" ], "products": [ "species_113581", "species_482807" ], "modifiers": [ [ "species_10051072", "catalyst" ] ], "additional_components": [ "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "species_110614", "species_29438", "species_500739", "species_29892", "species_29494", "species_29604", "species_30185", "species_30187", "F1N6T4", "ENSBTAT00000047964" ] }, "reaction_10077890": { "compartment": "compartment_5460", "id": "reaction_10077890", "reactome": "R-BTA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10077887", "catalyst" ] ], "additional_components": [ "species_727810", "species_109386", "species_76577", "species_109378", "species_29370", "CHEBI:16174", "CHEBI:28846", "species_110094", "ENSBTAT00000043366" ] }, "reaction_10082948": { "compartment": "compartment_5460", "id": "reaction_10082948", "reactome": "R-BTA-6810472", "name": "NUDT13 hydrolyses AP6A to AP4 and ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810468", "species_113521" ], "products": [ "species_113581", "species_6810471" ], "modifiers": [ [ "species_10082945", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000407" ] }, "reaction_10035047": { "compartment": "compartment_7660", "id": "reaction_10035047", "reactome": "R-BTA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10035044", "catalyst" ] ], "additional_components": [ "A0A3Q1MT44", "ENSBTAT00000070515" ] }, "reaction_10035481": { "compartment": "compartment_70101", "id": "reaction_10035481", "reactome": "R-BTA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10034953": { "compartment": "compartment_70101", "id": "reaction_10034953", "reactome": "R-BTA-73589", "name": "5,6-dihydrouracil + H2O => beta-ureidopropionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73584" ], "products": [ "species_73588" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10036267": { "compartment": "compartment_5460", "id": "reaction_10036267", "reactome": "R-BTA-109514", "name": "TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500420", "species_113521" ], "products": [ "species_113548", "species_500421" ], "modifiers": [ [ "species_10036264", "catalyst" ] ], "additional_components": [ "species_109366", "species_500742", "CHEBI:28895", "species_109402", "CHEBI:28070", "species_83928", "CHEBI:16450", "CHEBI:16704", "species_29926", "E1B8C1", "ENSBTAT00000043576" ] }, "reaction_10036209": { "compartment": "compartment_984", "id": "reaction_10036209", "reactome": "R-BTA-109291", "name": "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500316" ], "products": [ "species_109277", "species_500318" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_109402", "species_727810", "species_109366", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035009": { "compartment": "compartment_70101", "id": "reaction_10035009", "reactome": "R-BTA-73618", "name": "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73541" ], "products": [ "species_73617" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10035011": { "compartment": "compartment_70101", "id": "reaction_10035011", "reactome": "R-BTA-73620", "name": "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73617" ], "products": [ "species_113528", "species_73619", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036258": { "compartment": "compartment_70101", "id": "reaction_10036258", "reactome": "R-BTA-109480", "name": "TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500414" ], "products": [ "species_29372", "species_500415" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "CHEBI:28070", "CHEBI:28895", "species_109366", "species_500742", "CHEBI:46322", "species_109402", "CHEBI:16450", "CHEBI:16704", "species_83928", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10034962": { "compartment": "compartment_70101", "id": "reaction_10034962", "reactome": "R-BTA-73591", "name": "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73588" ], "products": [ "species_113528", "species_73590", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036229": { "compartment": "compartment_70101", "id": "reaction_10036229", "reactome": "R-BTA-109380", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10036247": { "compartment": "compartment_70101", "id": "reaction_10036247", "reactome": "R-BTA-109449", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036244", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "Q32L46", "ENSBTAT00000033700" ] }, "reaction_10065163": { "compartment": "compartment_876", "id": "reaction_10065163", "reactome": "R-BTA-2230938", "name": "Hemoglobin:Haptoglobin:CD163 is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065129" ], "products": [ "species_10065161" ], "modifiers": [], "additional_components": [ "P85521", "ENSBTAT00000026215", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_113533", "P85521", "ENSBTAT00000026215", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533" ] }, "reaction_10064765": { "compartment": "compartment_984", "id": "reaction_10064765", "reactome": "R-BTA-2168897", "name": "LRP1 (CD91) binds Hemopexin:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064755", "species_10064761" ], "products": [ "species_10064763" ], "modifiers": [], "additional_components": [ "A0A452DI25", "ENSBTAT00000004635", "species_71185", "ENSBTAT00000017556", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10064753": { "compartment": "compartment_984", "id": "reaction_10064753", "reactome": "R-BTA-2168884", "name": "Ferriheme is transferred from Methemoglobin to Hemopexin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_10064747" ], "products": [ "species_10064751", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_917955", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10064757": { "compartment": "compartment_984", "id": "reaction_10064757", "reactome": "R-BTA-2168886", "name": "Hemopexin binds Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10064747" ], "products": [ "species_10064755" ], "modifiers": [], "additional_components": [ "species_71185", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10065173": { "compartment": "compartment_24337", "id": "reaction_10065173", "reactome": "R-BTA-2230983", "name": "LRP1:Hemopexin:heme is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064763" ], "products": [ "species_10065171" ], "modifiers": [], "additional_components": [ "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "species_917955" ] } }, "collapsed_reaction_dictionary": { "reaction_10087663": { "compartment": "compartment_70101", "id": "reaction_10087663", "reactome": "R-BTA-8950181", "name": "Y693-STAT4 dimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087657" ], "products": [ "species_10087661" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087795": { "compartment": "compartment_70101", "id": "reaction_10087795", "reactome": "R-BTA-8950778", "name": "p-Y693-STAT4 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087655" ], "products": [ "species_10087657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087650": { "compartment": "compartment_70101", "id": "reaction_10087650", "reactome": "R-BTA-8950179", "name": "IL12B translocates from the cytosol to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087648" ], "products": [ "species_10049902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077926", "ENSBTAT00000077926" ] }, "reaction_10087732": { "compartment": "compartment_17957", "id": "reaction_10087732", "reactome": "R-BTA-8950410", "name": "IL12B:IL12B translocates from ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087728" ], "products": [ "species_10087730" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10088519": { "compartment": "compartment_70101", "id": "reaction_10088519", "reactome": "R-BTA-8952807", "name": "p-Y693-STAT4 dissociates after IL12:IL12R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088517" ], "products": [ "species_10087655" ], "modifiers": [], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1N0R2", "ENSBTAT00000030584", "ENSBTAT00000030584" ] }, "reaction_10045423": { "compartment": "compartment_984", "id": "reaction_10045423", "reactome": "R-BTA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10046151": { "compartment": "compartment_70101", "id": "reaction_10046151", "reactome": "R-BTA-379382", "name": "MAOA:FAD deaminates DA to DOPAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_159362" ], "products": [ "species_9677997", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10046153": { "compartment": "compartment_70101", "id": "reaction_10046153", "reactome": "R-BTA-379395", "name": "MAOA:FAD deaminates 3MT to HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954997", "species_29356", "species_29368" ], "products": [ "species_9677992", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10088657": { "compartment": "compartment_70101", "id": "reaction_10088657", "reactome": "R-BTA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10088654", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003905" ] }, "reaction_10046552": { "compartment": "compartment_5460", "id": "reaction_10046552", "reactome": "R-BTA-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_380598" ], "products": [ "species_113529", "species_380593", "species_29362" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10038000": { "compartment": "compartment_70101", "id": "reaction_10038000", "reactome": "R-BTA-141186", "name": "MAOA:FAD oxidatively deaminates of 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_209914", "species_29368" ], "products": [ "species_500604", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10078658": { "compartment": "compartment_70101", "id": "reaction_10078658", "reactome": "R-BTA-6798044", "name": "BTG2 binds CCR4-NOT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078654", "species_10078604" ], "products": [ "species_10078656" ], "modifiers": [], "additional_components": [ "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100", "ENSBTAT00000020860", "F1MNK6", "ENSBTAT00000020860", "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100" ] }, "reaction_10081380": { "compartment": "compartment_70101", "id": "reaction_10081380", "reactome": "R-BTA-6801675", "name": "PLK2 phosphorylates NPM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10081359" ], "products": [ "species_29370", "species_10081373" ], "modifiers": [ [ "species_10081377", "catalyst" ] ], "additional_components": [ "A0A3Q1LXL7", "ENSBTAT00000054559", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "ENSBTAT00000022307" ] }, "reaction_10081499": { "compartment": "compartment_70101", "id": "reaction_10081499", "reactome": "R-BTA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037648" ], "products": [ "species_10037650" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012154", "Q0VC36", "ENSBTAT00000012154" ] }, "reaction_10078349": { "compartment": "compartment_7660", "id": "reaction_10078349", "reactome": "R-BTA-6791235", "name": "GADD45A binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077951", "species_10078345" ], "products": [ "species_10078347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033450", "ENSBTAT00000044590", "Q2TA06", "ENSBTAT00000044590", "Q3ZBN6", "ENSBTAT00000033450" ] }, "reaction_10077955": { "compartment": "compartment_7660", "id": "reaction_10077955", "reactome": "R-BTA-6791109", "name": "GADD45A binds PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039892", "species_10077951" ], "products": [ "species_10077953" ], "modifiers": [], "additional_components": [ "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000033450", "Q3ZBN6", "ENSBTAT00000033450", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10088542": { "compartment": "compartment_7660", "id": "reaction_10088542", "reactome": "R-BTA-8953013", "name": "E2F7 binds E2F8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530", "species_10088538" ], "products": [ "species_10088540" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10088546": { "compartment": "compartment_7660", "id": "reaction_10088546", "reactome": "R-BTA-8953037", "name": "E2F8 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088538" ], "products": [ "species_10088544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675" ] }, "reaction_10088534": { "compartment": "compartment_7660", "id": "reaction_10088534", "reactome": "R-BTA-8952996", "name": "E2F7 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530" ], "products": [ "species_10088532" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10041386": { "compartment": "compartment_70101", "id": "reaction_10041386", "reactome": "R-BTA-193964", "name": "CYP21A2 21-hydroxylates PROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_194037", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041393": { "compartment": "compartment_5460", "id": "reaction_10041393", "reactome": "R-BTA-193965", "name": "CYP11B2 oxidises 18HCORST to ALDO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194012", "species_113533", "species_113529", "species_113600" ], "products": [ "species_193982", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041269": { "compartment": "compartment_70101", "id": "reaction_10041269", "reactome": "R-BTA-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041267", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10041397": { "compartment": "compartment_5460", "id": "reaction_10041397", "reactome": "R-BTA-193995", "name": "CYP11B2 18-hydroxylates CORST to 18HCORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_194005", "species_113600" ], "products": [ "species_194012", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041719": { "compartment": "compartment_70101", "id": "reaction_10041719", "reactome": "R-BTA-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_196344", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041415": { "compartment": "compartment_5460", "id": "reaction_10041415", "reactome": "R-BTA-194017", "name": "CYP11B2 oxidises 11DCORST to CORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193988", "species_113600" ], "products": [ "species_113563", "species_194005", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10076281": { "compartment": "compartment_70101", "id": "reaction_10076281", "reactome": "R-BTA-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10076278", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008272" ] }, "reaction_10077113": { "compartment": "compartment_5460", "id": "reaction_10077113", "reactome": "R-BTA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10077110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002073" ] }, "reaction_10041277": { "compartment": "compartment_70101", "id": "reaction_10041277", "reactome": "R-BTA-193060", "name": "CYP19A1 hydroxylates ANDST to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193079", "species_29364" ], "products": [ "species_29356", "species_193066", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10051676": { "compartment": "compartment_70101", "id": "reaction_10051676", "reactome": "R-BTA-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193066", "species_29364" ], "products": [ "species_193132", "species_29366" ], "modifiers": [ [ "species_10051673", "catalyst" ] ], "additional_components": [ "Q1JQD0", "ENSBTAT00000064720" ] }, "reaction_10041299": { "compartment": "compartment_70101", "id": "reaction_10041299", "reactome": "R-BTA-193143", "name": "CYP19A1 hydroxylates TEST to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_193057" ], "products": [ "species_193132", "species_29356", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10084679": { "compartment": "compartment_70101", "id": "reaction_10084679", "reactome": "R-BTA-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10084676", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004193" ] }, "reaction_10041692": { "compartment": "compartment_70616", "id": "reaction_10041692", "reactome": "R-BTA-196086", "name": "Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041690" ], "products": [ "species_193156", "species_10041688" ], "modifiers": [], "additional_components": [ "Q28918", "ENSBTAT00000047426", "species_193840", "ENSBTAT00000047426" ] }, "reaction_10041716": { "compartment": "compartment_17906", "id": "reaction_10041716", "reactome": "R-BTA-196126", "name": "CHOL translocates from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041714", "species_10041688" ], "products": [ "species_10041712", "species_10041690" ], "modifiers": [], "additional_components": [ "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "species_193840", "ENSBTAT00000047426", "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "Q28918", "ENSBTAT00000047426", "species_193840" ] }, "reaction_10041684": { "compartment": "compartment_70101", "id": "reaction_10041684", "reactome": "R-BTA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10041290": { "compartment": "compartment_70101", "id": "reaction_10041290", "reactome": "R-BTA-193070", "name": "CYP17A1 cleaves 17aHPREG to DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193124", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_176626" ], "modifiers": [ [ "species_10041281", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189", "ENSBTAT00000010386" ] }, "reaction_10050650": { "compartment": "compartment_70101", "id": "reaction_10050650", "reactome": "R-BTA-469659", "name": "SRD5A1 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10050647", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020570", "ENSBTAT00000010386" ] }, "reaction_10041293": { "compartment": "compartment_70101", "id": "reaction_10041293", "reactome": "R-BTA-193072", "name": "CYP17A1 17-hydroxylates P4 to 17aHPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193092" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041295": { "compartment": "compartment_70101", "id": "reaction_10041295", "reactome": "R-BTA-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176626", "species_29360" ], "products": [ "species_70106", "species_193079", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "ENSBTAT00000010386" ] }, "reaction_10092062": { "compartment": "compartment_70101", "id": "reaction_10092062", "reactome": "R-BTA-9705713", "name": "SRD5A2 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10092059", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004043", "ENSBTAT00000010386" ] }, "reaction_10041297": { "compartment": "compartment_70101", "id": "reaction_10041297", "reactome": "R-BTA-193099", "name": "CYP17A1 cleaves 17aHPROG to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_193079" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10092065": { "compartment": "compartment_70101", "id": "reaction_10092065", "reactome": "R-BTA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10069495", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855", "ENSBTAT00000010386" ] }, "reaction_10041284": { "compartment": "compartment_70101", "id": "reaction_10041284", "reactome": "R-BTA-193068", "name": "CYP17A1 17-hydroxylates PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193124" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041721": { "compartment": "compartment_70101", "id": "reaction_10041721", "reactome": "R-BTA-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_196366", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10057880": { "compartment": "compartment_984", "id": "reaction_10057880", "reactome": "R-BTA-1449687", "name": "Corticosteroids bind to CBG in blood", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1449707", "species_10057876" ], "products": [ "species_10057878" ], "modifiers": [], "additional_components": [ "species_193982", "species_193055", "species_194011", "species_193988", "ENSBTAT00000023402", "E1BF81", "ENSBTAT00000023402", "species_193982", "species_193055", "species_194011", "species_193988" ] }, "reaction_10041424": { "compartment": "compartment_17957", "id": "reaction_10041424", "reactome": "R-BTA-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193977", "species_29366" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10041421", "catalyst" ] ], "additional_components": [ "F6PTG3", "ENSBTAT00000020078" ] }, "reaction_10041379": { "compartment": "compartment_70101", "id": "reaction_10041379", "reactome": "R-BTA-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041395": { "compartment": "compartment_70101", "id": "reaction_10041395", "reactome": "R-BTA-193981", "name": "CYP21A2 oxidises 17HPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_193966", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041412": { "compartment": "compartment_5460", "id": "reaction_10041412", "reactome": "R-BTA-193997", "name": "CYP11B1 oxidises 11DCORT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193998", "species_113529", "species_113600" ], "products": [ "species_113563", "species_194011", "species_113521" ], "modifiers": [ [ "species_10041409", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "F1MG97", "ENSBTAT00000055451", "F1MU47", "ENSBTAT00000006034", "F1MWH3", "ENSBTAT00000055451", "ENSBTAT00000010386" ] }, "reaction_10034240": { "compartment": "compartment_70101", "id": "reaction_10034240", "reactome": "R-BTA-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29398", "species_73473" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10089721": { "compartment": "compartment_5460", "id": "reaction_10089721", "reactome": "R-BTA-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089717", "species_9010792" ], "products": [ "species_10089719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011523", "F6Q200", "ENSBTAT00000011523" ] }, "reaction_10089728": { "compartment": "compartment_5460", "id": "reaction_10089728", "reactome": "R-BTA-9011595", "name": "GSTZ1 dimer dehalogenates DCA to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_113521" ], "products": [ "species_904849", "species_3301973" ], "modifiers": [ [ "species_10089725", "catalyst" ], [ "species_1655887", "catalyst" ], [ "species_9010792", "inhibitor" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10076468": { "compartment": "compartment_70101", "id": "reaction_10076468", "reactome": "R-BTA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10076465", "catalyst" ] ], "additional_components": [ "species_29426", "A4FUZ1", "ENSBTAT00000016884" ] }, "reaction_10033671": { "compartment": "compartment_70101", "id": "reaction_10033671", "reactome": "R-BTA-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_29398", "species_73473" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10051980": { "compartment": "compartment_70616", "id": "reaction_10051980", "reactome": "R-BTA-880050", "name": "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_880013" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051977", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020226" ] }, "reaction_10051973": { "compartment": "compartment_5460", "id": "reaction_10051973", "reactome": "R-BTA-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051970", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_880067", "catalyst" ], [ "species_113527", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081426" ] }, "reaction_10033868": { "compartment": "compartment_5460", "id": "reaction_10033868", "reactome": "R-BTA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10033865", "catalyst" ] ], "additional_components": [ "Q29RK1", "ENSBTAT00000005730" ] }, "reaction_10050446": { "compartment": "compartment_5460", "id": "reaction_10050446", "reactome": "R-BTA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10050443", "catalyst" ] ], "additional_components": [ "Q04467", "ENSBTAT00000018741", "species_113527" ] }, "reaction_10089808": { "compartment": "compartment_5460", "id": "reaction_10089808", "reactome": "R-BTA-9012349", "name": "ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_113544" ], "products": [ "species_113529", "species_113557", "species_113600", "species_29376" ], "modifiers": [ [ "species_10089805", "catalyst" ] ], "additional_components": [ "species_29926", "Q0VCX7", "ENSBTAT00000000306" ] }, "reaction_10089795": { "compartment": "compartment_5460", "id": "reaction_10089795", "reactome": "R-BTA-9012268", "name": "ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544", "species_113526" ], "products": [ "species_113529", "species_113557", "species_29362", "species_29376" ], "modifiers": [ [ "species_10089792", "catalyst" ], [ "species_113588", "catalyst" ], [ "species_113593", "inhibitor" ] ], "additional_components": [ "A0A3Q1MWG7", "ENSBTAT00000074198", "species_29926" ] }, "reaction_10050437": { "compartment": "compartment_5462", "id": "reaction_10050437", "reactome": "R-BTA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10050434", "catalyst" ] ], "additional_components": [ "P11024", "ENSBTAT00000080867" ] }, "reaction_10089782": { "compartment": "compartment_5460", "id": "reaction_10089782", "reactome": "R-BTA-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_113557", "species_29376" ], "modifiers": [ [ "species_10089779", "catalyst" ] ], "additional_components": [ "Q2HJ98", "ENSBTAT00000046873", "species_29926" ] }, "reaction_10073835": { "compartment": "compartment_17938", "id": "reaction_10073835", "reactome": "R-BTA-5672017", "name": "Rheb in the MTORC1 complex hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10074507": { "compartment": "compartment_5683628", "id": "reaction_10074507", "reactome": "R-BTA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074495" ], "products": [ "species_10074505" ], "modifiers": [ [ "species_10052773", "catalyst" ] ], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "species_1602375", "species_1602375", "O41515", "ENSBTAT00000015449", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10074365": { "compartment": "compartment_70101", "id": "reaction_10074365", "reactome": "R-BTA-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10074362", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10074381": { "compartment": "compartment_70101", "id": "reaction_10074381", "reactome": "R-BTA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074371", "species_10074377" ], "products": [ "species_10074379" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074415": { "compartment": "compartment_70101", "id": "reaction_10074415", "reactome": "R-BTA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074399", "species_10074377" ], "products": [ "species_10074413" ], "modifiers": [], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449" ] }, "reaction_10074142": { "compartment": "compartment_70101", "id": "reaction_10074142", "reactome": "R-BTA-5673768", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073828", "species_113592" ], "products": [ "species_29370", "species_10074140" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10074302": { "compartment": "compartment_70101", "id": "reaction_10074302", "reactome": "R-BTA-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693050", "species_10074298" ], "products": [ "species_10074300" ], "modifiers": [], "additional_components": [ "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "species_5693050" ] }, "reaction_10090398": { "compartment": "compartment_70101", "id": "reaction_10090398", "reactome": "R-BTA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074379" ], "products": [ "species_10074653" ], "modifiers": [], "additional_components": [ "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074659": { "compartment": "compartment_70101", "id": "reaction_10074659", "reactome": "R-BTA-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074655", "species_10074653" ], "products": [ "species_10074657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083652", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A4FUE9", "ENSBTAT00000083652" ] }, "reaction_10070265": { "compartment": "compartment_17927", "id": "reaction_10070265", "reactome": "R-BTA-5205681", "name": "Pink1 is cleaved on healthy mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070263" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10070218": { "compartment": "compartment_70101", "id": "reaction_10070218", "reactome": "R-BTA-5205649", "name": "p62 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10070210" ], "products": [ "species_10070216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "O41515", "ENSBTAT00000015449" ] }, "reaction_10070259": { "compartment": "compartment_70101", "id": "reaction_10070259", "reactome": "R-BTA-5205661", "name": "Pink1 is recruited from the cytoplasm to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070224" ], "products": [ "species_10070226" ], "modifiers": [ [ "species_10070256", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455", "A6QPI6", "ENSBTAT00000013405", "Q2KI08", "ENSBTAT00000070920", "Q1LZB5", "ENSBTAT00000032251", "Q08E34", "ENSBTAT00000019001", "A8YXZ8", "ENSBTAT00000046547", "A6H7B1", "ENSBTAT00000000733", "Q56JY4", "ENSBTAT00000011817" ] }, "reaction_10070261": { "compartment": "compartment_17906", "id": "reaction_10070261", "reactome": "R-BTA-5205672", "name": "Uncleaved Pink1 accumulates in damaged mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10088891": { "compartment": "compartment_70101", "id": "reaction_10088891", "reactome": "R-BTA-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10087624" ], "products": [ "species_10088889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "ENSBTAT00000002144", "F1N5S9", "ENSBTAT00000002144", "O41515", "ENSBTAT00000015449" ] }, "reaction_10087615": { "compartment": "compartment_70101", "id": "reaction_10087615", "reactome": "R-BTA-8948139", "name": "p-S13-FUNDC1 is dephosphorylated by PGAM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087608" ], "products": [ "species_10087605" ], "modifiers": [ [ "species_10087612", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000009887" ] }, "reaction_10087621": { "compartment": "compartment_70101", "id": "reaction_10087621", "reactome": "R-BTA-8948143", "name": "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087608" ], "products": [ "species_10087618", "species_29370" ], "modifiers": [ [ "species_10040957", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000011767" ] }, "reaction_10073831": { "compartment": "compartment_17938", "id": "reaction_10073831", "reactome": "R-BTA-5672010", "name": "Active MTORC1 phosphorylates ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073822" ], "products": [ "species_10073828", "species_29370" ], "modifiers": [ [ "species_10073822", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10050514": { "compartment": "compartment_876", "id": "reaction_10050514", "reactome": "R-BTA-451283", "name": "kainate receptor binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10050510" ], "products": [ "species_10050512" ], "modifiers": [], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10050517": { "compartment": "compartment_70101", "id": "reaction_10050517", "reactome": "R-BTA-451311", "name": "Activation of Ca-permeable Kainate receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10050512", "catalyst" ] ], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10045419": { "compartment": "compartment_876", "id": "reaction_10045419", "reactome": "R-BTA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10045421": { "compartment": "compartment_70101", "id": "reaction_10045421", "reactome": "R-BTA-374909", "name": "Metabolism of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209789", "species_29356", "species_29368" ], "products": [ "species_5279533", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10039481": { "compartment": "compartment_70101", "id": "reaction_10039481", "reactome": "R-BTA-166869", "name": "TRAF6 binds MEKK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10039469" ], "products": [ "species_10039475" ], "modifiers": [ [ "species_10039479", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021630", "ENSBTAT00000018325", "E1B847", "ENSBTAT00000018325", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000020029" ] }, "reaction_10050256": { "compartment": "compartment_70101", "id": "reaction_10050256", "reactome": "R-BTA-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039518" ], "products": [ "species_10039505" ], "modifiers": [], "additional_components": [ "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10042826": { "compartment": "compartment_7660", "id": "reaction_10042826", "reactome": "R-BTA-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10042823", "catalyst" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "F1N1S8", "ENSBTAT00000007277" ] }, "reaction_10043488": { "compartment": "compartment_7660", "id": "reaction_10043488", "reactome": "R-BTA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10043479", "catalyst" ], [ "species_10043486", "inhibitor" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "Q2T9T7", "ENSBTAT00000078874", "F1MM08", "ENSBTAT00000061049", "A6QLS1", "ENSBTAT00000029212", "Q2KJ36", "ENSBTAT00000006022", "Q2T9T7", "ENSBTAT00000078874", "Q2YDN8", "ENSBTAT00000007054" ] }, "reaction_10041950": { "compartment": "compartment_7660", "id": "reaction_10041950", "reactome": "R-BTA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10041927" ], "products": [ "species_113582", "species_10041945" ], "modifiers": [ [ "species_10041947", "catalyst" ] ], "additional_components": [ "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A5PKJ4", "ENSBTAT00000001347" ] }, "reaction_10050208": { "compartment": "compartment_7660", "id": "reaction_10050208", "reactome": "R-BTA-450292", "name": "Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039493", "species_10050204" ], "products": [ "species_10050206" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005660", "O77628", "ENSBTAT00000005660", "Q08DH1", "ENSBTAT00000005279" ] }, "reaction_10039508": { "compartment": "compartment_7660", "id": "reaction_10039508", "reactome": "R-BTA-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10039489" ], "products": [ "species_113582", "species_10039493" ], "modifiers": [ [ "species_10039505", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005279", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10050218": { "compartment": "compartment_70101", "id": "reaction_10050218", "reactome": "R-BTA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050214" ], "products": [ "species_10050216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307" ] }, "reaction_10050254": { "compartment": "compartment_70101", "id": "reaction_10050254", "reactome": "R-BTA-450346", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10050251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LT51", "ENSBTAT00000068866", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176" ] }, "reaction_10050192": { "compartment": "compartment_7660", "id": "reaction_10050192", "reactome": "R-BTA-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050185" ], "products": [ "species_113582", "species_10050189" ], "modifiers": [ [ "species_10050185", "catalyst" ] ], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050196": { "compartment": "compartment_70101", "id": "reaction_10050196", "reactome": "R-BTA-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050189" ], "products": [ "species_10050194" ], "modifiers": [], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476" ] }, "reaction_10050231": { "compartment": "compartment_7660", "id": "reaction_10050231", "reactome": "R-BTA-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050228" ], "products": [ "species_113582", "species_10050185" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10069253": { "compartment": "compartment_876", "id": "reaction_10069253", "reactome": "R-BTA-3928651", "name": "NGEF exchanges GTP for GDP on RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069250", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "Q08DA6", "ENSBTAT00000011773" ] }, "reaction_10077455": { "compartment": "compartment_876", "id": "reaction_10077455", "reactome": "R-BTA-6784189", "name": "JAKs bind LIFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077414", "species_10049952" ], "products": [ "species_10077416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709" ] }, "reaction_10077422": { "compartment": "compartment_876", "id": "reaction_10077422", "reactome": "R-BTA-6783524", "name": "OSM,LIF,CTF1 receptor complex binds gp130", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049956", "species_10077418" ], "products": [ "species_10077420" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10077424": { "compartment": "compartment_876", "id": "reaction_10077424", "reactome": "R-BTA-6783552", "name": "OSM binds LIFR:JAKs,OSMR:JAKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077410", "species_10077416" ], "products": [ "species_10077418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515" ] }, "reaction_10065517": { "compartment": "compartment_876", "id": "reaction_10065517", "reactome": "R-BTA-2424480", "name": "PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065514", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "F1MI53", "ENSBTAT00000074586", "A0A3Q1NAW3", "ENSBTAT00000070846", "A0A2Z2AM52", "ENSBTAT00000080723", "A3R3B5", "ENSBTAT00000077363", "A0A3Q1M7L0", "ENSBTAT00000075285", "A8E4Q0", "ENSBTAT00000031648", "A0A3Q1NM98", "ENSBTAT00000071353", "F1MHY4", "ENSBTAT00000006472", "A3R3B4", "ENSBTAT00000077363", "F1MPK9", "ENSBTAT00000055860", "A0A140T8B5", "ENSBTAT00000037859", "A0A3Q1N4Y9", "ENSBTAT00000068807", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0JNB0", "ENSBTAT00000015730", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065491": { "compartment": "compartment_876", "id": "reaction_10065491", "reactome": "R-BTA-2424477", "name": "SOS mediated nucleotide exchange of RAS (SHC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040851": { "compartment": "compartment_12045", "id": "reaction_10040851", "reactome": "R-BTA-190681", "name": "Connexin oligomerization in endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040846" ], "products": [ "species_10040848" ], "modifiers": [ [ "species_10040846", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027331", "O18968", "ENSBTAT00000027331", "ENSBTAT00000027331" ] }, "reaction_10049067": { "compartment": "compartment_114584", "id": "reaction_10049067", "reactome": "R-BTA-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_114565" ], "modifiers": [ [ "species_10049064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013298" ] }, "reaction_10051002": { "compartment": "compartment_984", "id": "reaction_10051002", "reactome": "R-BTA-482770", "name": "Release of platelet secretory granule components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050998" ], "products": [ "species_10051000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "ENSBTAT00000009564" ] }, "reaction_10050924": { "compartment": "compartment_876", "id": "reaction_10050924", "reactome": "R-BTA-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050904" ], "products": [ "species_10050922" ], "modifiers": [], "additional_components": [ "species_29438", "A7E3W2", "ENSBTAT00000001802", "species_29370", "species_29926", "Q29RS5", "ENSBTAT00000084323", "species_113592", "A0A3Q1M5Q6", "ENSBTAT00000076112", "A5PKI3", "ENSBTAT00000073296", "species_29372", "A0A452DIU4", "ENSBTAT00000024391", "species_74016", "A0A3Q1LTE4", "ENSBTAT00000080253", "Q27967", "ENSBTAT00000002631", "species_209914", "species_29420", "species_111294", "A6H754", "ENSBTAT00000022777", "species_74016", "species_29438", "Q27967", "ENSBTAT00000002631", "species_29370", "A6H754", "ENSBTAT00000022777", "species_111294", "A0A452DIU4", "ENSBTAT00000024391", "species_29926", "species_113592", "Q29RS5", "ENSBTAT00000084323", "A0A3Q1LTE4", "ENSBTAT00000080253", "species_209914", "A0A3Q1M5Q6", "ENSBTAT00000076112", "species_29372", "A5PKI3", "ENSBTAT00000073296", "species_29420", "A7E3W2", "ENSBTAT00000001802" ] }, "reaction_10050994": { "compartment": "compartment_876", "id": "reaction_10050994", "reactome": "R-BTA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050980" ], "products": [ "species_10050992" ], "modifiers": [], "additional_components": [ "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "A0A3Q1LI93", "ENSBTAT00000075662", "P26201", "ENSBTAT00000080828", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A5PK28", "ENSBTAT00000067657", "A0A3Q1LEU1", "ENSBTAT00000081148", "A0A3Q1LN74", "ENSBTAT00000074339", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LI93", "ENSBTAT00000075662", "A5PK28", "ENSBTAT00000067657", "P26201", "ENSBTAT00000080828", "A0A3Q1LN74", "ENSBTAT00000074339", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "A0A3Q1LEU1", "ENSBTAT00000081148" ] }, "reaction_10050948": { "compartment": "compartment_876", "id": "reaction_10050948", "reactome": "R-BTA-481010", "name": "Surface deployment of platelet dense granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050938" ], "products": [ "species_10050946" ], "modifiers": [], "additional_components": [ "Q8HZJ5", "ENSBTAT00000078091", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "Q8HZJ5", "ENSBTAT00000078091" ] }, "reaction_10050870": { "compartment": "compartment_876", "id": "reaction_10050870", "reactome": "R-BTA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050802" ], "products": [ "species_10050868" ], "modifiers": [], "additional_components": [ "A0A452DIX0", "ENSBTAT00000026577", "P17697", "ENSBTAT00000007324", "A4IF69", "ENSBTAT00000004806", "F1MY12", "ENSBTAT00000016092", "A0A140T8C8", "ENSBTAT00000053071", "A0A0A0MP92", "ENSBTAT00000011576", "C4PU73", "ENSBTAT00000009718", "A0A0A0MPA0", "ENSBTAT00000038516", "G3N1U4", "ENSBTAT00000064475", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A0A0MP89", "ENSBTAT00000009261", "A0A452DJK6", "ENSBTAT00000064935", "E1BMJ0", "ENSBTAT00000021638", "Q9XS50", "ENSBTAT00000019613", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P28800", "ENSBTAT00000027793", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "A6QP91", "ENSBTAT00000015925", "E1BBY0", "ENSBTAT00000051964", "E1B726", "ENSBTAT00000001674", "A0A452DIJ9", "ENSBTAT00000019232", "G3X7J5", "ENSBTAT00000032623", "F1MD83", "ENSBTAT00000015874", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1M2H1", "ENSBTAT00000067311", "Q17QL4", "ENSBTAT00000007016", "A4IFA6", "ENSBTAT00000007913", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LPG8", "ENSBTAT00000083114", "G5E5W1", "ENSBTAT00000036726", "P12763", "ENSBTAT00000000673", "F1MX05", "ENSBTAT00000004949", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "Q2HJ33", "ENSBTAT00000009160", "P07455", "ENSBTAT00000014713", "A0A452DIJ9", "ENSBTAT00000019232", "P12763", "ENSBTAT00000000673", "Q5GN72", "ENSBTAT00000022991", "P07455", "ENSBTAT00000014713", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "E1BBY0", "ENSBTAT00000051964", "A4IFA6", "ENSBTAT00000007913", "E1BMJ0", "ENSBTAT00000021638", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "P17697", "ENSBTAT00000007324", "F1MY12", "ENSBTAT00000016092", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1M2H1", "ENSBTAT00000067311", "A0A140T8C8", "ENSBTAT00000053071", "E1B726", "ENSBTAT00000001674", "A6QP91", "ENSBTAT00000015925", "A4IF69", "ENSBTAT00000004806", "F1MX05", "ENSBTAT00000004949", "G5E5W1", "ENSBTAT00000036726", "P28800", "ENSBTAT00000027793", "F1MD83", "ENSBTAT00000015874", "Q2HJ33", "ENSBTAT00000009160", "Q17QL4", "ENSBTAT00000007016", "A0A3Q1LPG8", "ENSBTAT00000083114", "G3X7J5", "ENSBTAT00000032623", "Q9XS50", "ENSBTAT00000019613", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A452DIX0", "ENSBTAT00000026577" ] }, "reaction_10051062": { "compartment": "compartment_70101", "id": "reaction_10051062", "reactome": "R-BTA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051036" ], "products": [ "species_10051060" ], "modifiers": [], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "F1MHC2", "ENSBTAT00000012094", "P80513", "ENSBTAT00000045083", "P63258", "ENSBTAT00000008132", "F1MRZ8", "ENSBTAT00000012724", "A0A3Q1MLQ7", "ENSBTAT00000074863", "A7YY77", "ENSBTAT00000034535", "F1MNQ4", "ENSBTAT00000039344", "A0A3Q1LP13", "ENSBTAT00000075491", "E1B8Z0", "ENSBTAT00000079099", "Q5E9F5", "ENSBTAT00000080925", "A0A3Q1MLQ7", "ENSBTAT00000074863", "F1MHC2", "ENSBTAT00000012094", "A7YY77", "ENSBTAT00000034535", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1LP13", "ENSBTAT00000075491", "F1MRZ8", "ENSBTAT00000012724", "Q5E9F5", "ENSBTAT00000080925", "F1MNQ4", "ENSBTAT00000039344", "P80513", "ENSBTAT00000045083", "E1B8Z0", "ENSBTAT00000079099", "P63258", "ENSBTAT00000008132" ] }, "reaction_10090306": { "compartment": "compartment_876", "id": "reaction_10090306", "reactome": "R-BTA-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090272", "species_10090302" ], "products": [ "species_10090304" ], "modifiers": [], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29438", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A5D7J5", "ENSBTAT00000024876", "species_29438" ] }, "reaction_10090311": { "compartment": "compartment_876", "id": "reaction_10090311", "reactome": "R-BTA-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090308" ], "products": [ "species_29420", "species_10090272" ], "modifiers": [ [ "species_10090308", "catalyst" ] ], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29420", "A5D7J5", "ENSBTAT00000024876", "species_29438", "A5D7J5", "ENSBTAT00000024876", "species_29420" ] }, "reaction_10081497": { "compartment": "compartment_70101", "id": "reaction_10081497", "reactome": "R-BTA-6803789", "name": "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6803743" ], "products": [ "species_193473", "species_449701" ], "modifiers": [ [ "species_10081494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074115" ] }, "reaction_10050153": { "compartment": "compartment_70101", "id": "reaction_10050153", "reactome": "R-BTA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10050150", "catalyst" ] ], "additional_components": [ "F1MZY2", "ENSBTAT00000023441", "A0A452DHW0", "ENSBTAT00000002867" ] }, "reaction_10081490": { "compartment": "compartment_70101", "id": "reaction_10081490", "reactome": "R-BTA-6803771", "name": "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803785", "species_113592" ], "products": [ "species_6803738", "species_70106", "species_29370" ], "modifiers": [ [ "species_10081487", "catalyst" ] ], "additional_components": [ "CHEBI:27459", "species_1678743", "species_449703", "species_6803743", "A0A452DJF8", "ENSBTAT00000019528" ] }, "reaction_10049778": { "compartment": "compartment_70101", "id": "reaction_10049778", "reactome": "R-BTA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10049775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086526" ] }, "reaction_10069593": { "compartment": "compartment_70101", "id": "reaction_10069593", "reactome": "R-BTA-4608852", "name": "SMURF1/2 ubiquitinates PRICKLE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069585" ], "products": [ "species_10069588" ], "modifiers": [ [ "species_10069590", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072372", "ENSBTAT00000072372", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069595": { "compartment": "compartment_70101", "id": "reaction_10069595", "reactome": "R-BTA-4608854", "name": "SMURF1/2 are recruited to the DVL2:PARD6A complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069581", "species_10042973" ], "products": [ "species_10069590" ], "modifiers": [], "additional_components": [ "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000043725", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069872": { "compartment": "compartment_876", "id": "reaction_10069872", "reactome": "R-BTA-5099886", "name": "WNT5A binding to FZD promotes PRICKLE1 degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069868", "species_10067196" ], "products": [ "species_10069870" ], "modifiers": [], "additional_components": [ "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10044480": { "compartment": "compartment_17960", "id": "reaction_10044480", "reactome": "R-BTA-215526", "name": "CYP4F3 20-hydroxylates LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215557", "species_113601" ], "products": [ "species_113519", "species_113564", "species_571314" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10071909": { "compartment": "compartment_12045", "id": "reaction_10071909", "reactome": "R-BTA-5602295", "name": "CYP4F22 20-hydroxylates TrXA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2142713", "species_29368", "species_29364" ], "products": [ "species_5602281", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066325" ] }, "reaction_10044151": { "compartment": "compartment_12045", "id": "reaction_10044151", "reactome": "R-BTA-211873", "name": "CYP4F2, 4F3 20-hydroxylate LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266056", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2161636" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10073037": { "compartment": "compartment_876", "id": "reaction_10073037", "reactome": "R-BTA-5654423", "name": "Activated FGFR4:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073033" ], "products": [ "species_10073035" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073041": { "compartment": "compartment_70101", "id": "reaction_10073041", "reactome": "R-BTA-5654425", "name": "Activated FGFR4 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065241" ], "products": [ "species_10073039" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073044": { "compartment": "compartment_70101", "id": "reaction_10073044", "reactome": "R-BTA-5654426", "name": "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073047": { "compartment": "compartment_70101", "id": "reaction_10073047", "reactome": "R-BTA-5654428", "name": "Activated FGFR4 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073039" ], "products": [ "species_29370", "species_10073033" ], "modifiers": [ [ "species_10073039", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10076847": { "compartment": "compartment_12045", "id": "reaction_10076847", "reactome": "R-BTA-5696119", "name": "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_5696122", "species_29368" ], "products": [ "species_29356", "species_1497857", "species_76116", "species_5696116" ], "modifiers": [ [ "species_10076844", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069764" ] }, "reaction_10035838": { "compartment": "compartment_70101", "id": "reaction_10035838", "reactome": "R-BTA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10035795": { "compartment": "compartment_70101", "id": "reaction_10035795", "reactome": "R-BTA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10035790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030932" ] }, "reaction_10035829": { "compartment": "compartment_70101", "id": "reaction_10035829", "reactome": "R-BTA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10035826", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LV95", "ENSBTAT00000067199" ] }, "reaction_10080887": { "compartment": "compartment_12045", "id": "reaction_10080887", "reactome": "R-BTA-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76103", "species_76194" ], "modifiers": [ [ "species_10080884", "catalyst" ] ], "additional_components": [ "Q70VZ7", "ENSBTAT00000011091", "F1MLQ3", "ENSBTAT00000010395", "G3MYF6", "ENSBTAT00000064201" ] }, "reaction_10090409": { "compartment": "compartment_7660", "id": "reaction_10090409", "reactome": "R-BTA-9021357", "name": "PRKCI phosphorylates ELF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10090404" ], "products": [ "species_113582", "species_10090404" ], "modifiers": [ [ "species_10090406", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011536", "ENSBTAT00000011536", "ENSBTAT00000061563" ] }, "reaction_10044826": { "compartment": "compartment_70101", "id": "reaction_10044826", "reactome": "R-BTA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10044815" ], "products": [ "species_29420", "species_10044819" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "P84080", "ENSBTAT00000010159", "species_29420", "P84080", "ENSBTAT00000010159", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10045538": { "compartment": "compartment_70101", "id": "reaction_10045538", "reactome": "R-BTA-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10045525", "species_10045531" ], "products": [ "species_10045527", "species_10045525", "species_10045533" ], "modifiers": [ [ "species_10045535", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10034921": { "compartment": "compartment_70101", "id": "reaction_10034921", "reactome": "R-BTA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034924": { "compartment": "compartment_70101", "id": "reaction_10034924", "reactome": "R-BTA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034927": { "compartment": "compartment_70101", "id": "reaction_10034927", "reactome": "R-BTA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10048761": { "compartment": "compartment_876", "id": "reaction_10048761", "reactome": "R-BTA-427656", "name": "SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048758", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084837" ] }, "reaction_10048754": { "compartment": "compartment_876", "id": "reaction_10048754", "reactome": "R-BTA-427645", "name": "SLC34A3 cotransports Pi, 2Na+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069253" ] }, "reaction_10065819": { "compartment": "compartment_984", "id": "reaction_10065819", "reactome": "R-BTA-2534248", "name": "DCN (decorin) degradation by MMP2, MMP3, MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065294" ], "products": [ "species_10065814", "species_10065812" ], "modifiers": [ [ "species_10065816", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004562", "ENSBTAT00000004562", "ENSBTAT00000004562", "F1MU56", "ENSBTAT00000006029", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059674": { "compartment": "compartment_984", "id": "reaction_10059674", "reactome": "R-BTA-1566962", "name": "Elastin degradation by elastin-degrading extracellular proteinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059657" ], "products": [ "species_10059665" ], "modifiers": [ [ "species_10059671", "catalyst" ] ], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTX6", "ENSBTAT00000013124", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10087324": { "compartment": "compartment_984", "id": "reaction_10087324", "reactome": "R-BTA-8940561", "name": "MMP7 cleaves OPTC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087311" ], "products": [ "species_10087319", "species_10087317", "species_10087315", "species_10087321" ], "modifiers": [ [ "species_10058184", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000006029" ] }, "reaction_10064649": { "compartment": "compartment_876", "id": "reaction_10064649", "reactome": "R-BTA-2167942", "name": "Collagen type XIII ectodomain shedding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064303" ], "products": [ "species_10064625", "species_10064623" ], "modifiers": [], "additional_components": [ "F6RND5", "ENSBTAT00000039811", "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10076984": { "compartment": "compartment_5460", "id": "reaction_10076984", "reactome": "R-BTA-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696409", "species_113521" ], "products": [ "species_113548", "species_5693978", "species_113556" ], "modifiers": [ [ "species_10076981", "catalyst" ] ], "additional_components": [ "E1B8R9", "ENSBTAT00000018115" ] }, "reaction_10059533": { "compartment": "compartment_984", "id": "reaction_10059533", "reactome": "R-BTA-1564142", "name": "Collagen type IV degradation by MMP2,3,4,9,10,12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526" ], "products": [ "species_10058166" ], "modifiers": [ [ "species_10059530", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059598": { "compartment": "compartment_984", "id": "reaction_10059598", "reactome": "R-BTA-1564164", "name": "Collagen type V degradation by MMP2,9,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058699" ], "products": [ "species_10059595" ], "modifiers": [ [ "species_10059528", "catalyst" ] ], "additional_components": [ "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "ENSBTAT00000013124" ] }, "reaction_10058561": { "compartment": "compartment_984", "id": "reaction_10058561", "reactome": "R-BTA-1474197", "name": "Collagen type II degradation by MMP1,3,8,13,PRSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058552" ], "products": [ "species_10057938" ], "modifiers": [ [ "species_10058558", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059441": { "compartment": "compartment_984", "id": "reaction_10059441", "reactome": "R-BTA-1564112", "name": "Collagen type VI degradation by MMP2,9,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282" ], "products": [ "species_10059434" ], "modifiers": [ [ "species_10059438", "catalyst" ] ], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000008025" ] }, "reaction_10064705": { "compartment": "compartment_984", "id": "reaction_10064705", "reactome": "R-BTA-2168038", "name": "Collagen type XV restin release", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064651" ], "products": [ "species_10064677", "species_10064703" ], "modifiers": [], "additional_components": [ "A0A3Q1M0N0", "ENSBTAT00000072268", "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10058193": { "compartment": "compartment_984", "id": "reaction_10058193", "reactome": "R-BTA-1454757", "name": "Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058168" ], "products": [], "modifiers": [ [ "species_10058190", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059651": { "compartment": "compartment_984", "id": "reaction_10059651", "reactome": "R-BTA-1564169", "name": "Collagen type VIII degradation by MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059648" ], "products": [ "species_10058052" ], "modifiers": [ [ "species_10058172", "catalyst" ] ], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "ENSBTAT00000021014" ] }, "reaction_10059689": { "compartment": "compartment_984", "id": "reaction_10059689", "reactome": "R-BTA-1592297", "name": "Full activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059684" ], "products": [ "species_10058172" ], "modifiers": [ [ "species_10059686", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "F1MU56", "ENSBTAT00000006029", "F1MMD4", "ENSBTAT00000008025", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059913": { "compartment": "compartment_984", "id": "reaction_10059913", "reactome": "R-BTA-1604712", "name": "Initial activation of proMMP7 by trypsin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059908", "species_10059906" ], "modifiers": [ [ "species_10059910", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "A7YWU9", "ENSBTAT00000028731" ] }, "reaction_10059787": { "compartment": "compartment_984", "id": "reaction_10059787", "reactome": "R-BTA-1592371", "name": "Initial activation of proMMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059746" ], "products": [ "species_10059750", "species_10059748" ], "modifiers": [ [ "species_10059784", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A7YWU6", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059869": { "compartment": "compartment_984", "id": "reaction_10059869", "reactome": "R-BTA-1602458", "name": "Activation of proMMP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059862" ], "products": [ "species_10059528" ], "modifiers": [ [ "species_10059866", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059804": { "compartment": "compartment_984", "id": "reaction_10059804", "reactome": "R-BTA-1592398", "name": "Activation of proMMP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059793" ], "products": [ "species_10058188" ], "modifiers": [ [ "species_10059801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063400", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "Q6H320", "ENSBTAT00000024677", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10059902": { "compartment": "compartment_984", "id": "reaction_10059902", "reactome": "R-BTA-1602473", "name": "Autocatalytic activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059706" ], "products": [ "species_10059684", "species_10059899" ], "modifiers": [ [ "species_10059706", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014" ] }, "reaction_10059918": { "compartment": "compartment_984", "id": "reaction_10059918", "reactome": "R-BTA-1604731", "name": "Autocatalytic activation of MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059748" ], "products": [ "species_10058180", "species_10059915" ], "modifiers": [ [ "species_10059748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124" ] }, "reaction_10059744": { "compartment": "compartment_984", "id": "reaction_10059744", "reactome": "R-BTA-1592362", "name": "Activation of proMMP7 by MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059735", "species_10058184" ], "modifiers": [ [ "species_10059741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "P25975", "ENSBTAT00000036427", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059731": { "compartment": "compartment_984", "id": "reaction_10059731", "reactome": "R-BTA-1592316", "name": "Initial activation of proMMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059704" ], "products": [ "species_10059708", "species_10059706" ], "modifiers": [ [ "species_10059728", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "A6QPI9", "ENSBTAT00000009636", "E1BAD2", "ENSBTAT00000054741", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674", "E1B8U1", "ENSBTAT00000052512", "E1BIP7", "ENSBTAT00000011737" ] }, "reaction_10059923": { "compartment": "compartment_984", "id": "reaction_10059923", "reactome": "R-BTA-1604763", "name": "Autocatalytic activation of MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059906" ], "products": [ "species_10059920", "species_10058184" ], "modifiers": [ [ "species_10059906", "catalyst" ], [ "species_1604783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "CHEBI:24505", "species_444761" ] }, "reaction_10060003": { "compartment": "compartment_17963", "id": "reaction_10060003", "reactome": "R-BTA-1605825", "name": "MT-MMPs are sorted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059897" ], "products": [ "species_10060001" ], "modifiers": [], "additional_components": [ "F1N797", "ENSBTAT00000061368", "F1N797", "ENSBTAT00000061368" ] }, "reaction_10068885": { "compartment": "compartment_984", "id": "reaction_10068885", "reactome": "R-BTA-3814820", "name": "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10068874", "species_10068872" ], "modifiers": [ [ "species_10068882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MF35", "ENSBTAT00000015593", "E1BEV7", "ENSBTAT00000001218", "A0A452DK38", "ENSBTAT00000036427", "F1N0X6", "ENSBTAT00000007834" ] }, "reaction_10065751": { "compartment": "compartment_984", "id": "reaction_10065751", "reactome": "R-BTA-2485148", "name": "Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063837" ], "products": [ "species_10065748" ], "modifiers": [ [ "species_10058176", "catalyst" ] ], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "ENSBTAT00000081947" ] }, "reaction_10087543": { "compartment": "compartment_876", "id": "reaction_10087543", "reactome": "R-BTA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087535" ], "products": [ "species_10087541" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068477", "A0A3Q1MG91", "ENSBTAT00000068477" ] }, "reaction_10059702": { "compartment": "compartment_984", "id": "reaction_10059702", "reactome": "R-BTA-1592314", "name": "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10059697", "species_10059695" ], "modifiers": [ [ "species_10059699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MTX6", "ENSBTAT00000013124", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10061174": { "compartment": "compartment_876", "id": "reaction_10061174", "reactome": "R-BTA-1861621", "name": "Cross-linking of FCGRIIA with IgG-coated Ag", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061170", "species_10039426" ], "products": [ "species_10061172" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029116", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1MHH9", "ENSBTAT00000029116" ] }, "reaction_10033690": { "compartment": "compartment_5460", "id": "reaction_10033690", "reactome": "R-BTA-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113552" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10033687", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021616" ] }, "reaction_10033706": { "compartment": "compartment_70101", "id": "reaction_10033706", "reactome": "R-BTA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10033703", "catalyst" ] ], "additional_components": [ "species_113527", "Q2KJ64", "ENSBTAT00000016461" ] }, "reaction_10033770": { "compartment": "compartment_70101", "id": "reaction_10033770", "reactome": "R-BTA-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113567", "species_29498" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10033767", "catalyst" ] ], "additional_components": [ "Q2KHW4", "ENSBTAT00000015468", "A0A3Q1N1S4", "ENSBTAT00000015847" ] }, "reaction_10033697": { "compartment": "compartment_5460", "id": "reaction_10033697", "reactome": "R-BTA-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113561", "species_29896" ], "products": [ "species_113548", "species_113581", "species_29676" ], "modifiers": [ [ "species_10033694", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022158" ] }, "reaction_10084008": { "compartment": "compartment_70101", "id": "reaction_10084008", "reactome": "R-BTA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083994", "species_10083992" ], "products": [ "species_10084006", "species_10083996" ], "modifiers": [], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1ME38", "ENSBTAT00000008985", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "F1ME38", "ENSBTAT00000008985", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088" ] }, "reaction_10084122": { "compartment": "compartment_70101", "id": "reaction_10084122", "reactome": "R-BTA-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084119" ], "products": [ "species_10033406", "species_10033404", "species_10033402" ], "modifiers": [ [ "species_10075812", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000026356" ] }, "reaction_10084113": { "compartment": "compartment_70101", "id": "reaction_10084113", "reactome": "R-BTA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033394" ], "products": [ "species_10033394", "species_10034499" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087088", "ENSBTAT00000087088", "ENSBTAT00000087088", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10084117": { "compartment": "compartment_70101", "id": "reaction_10084117", "reactome": "R-BTA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084115" ], "products": [ "species_10033398", "species_10034743" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010176", "ENSBTAT00000010176", "ENSBTAT00000010176", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10086702": { "compartment": "compartment_459", "id": "reaction_10086702", "reactome": "R-BTA-8939323", "name": "RNF181 binds BCL10 and Ubiquitin:E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086688", "species_10086698", "species_10043291" ], "products": [ "species_10086700" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10086710": { "compartment": "compartment_459", "id": "reaction_10086710", "reactome": "R-BTA-8939335", "name": "RNF181 polyubiquinates BCL10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086700", "species_10086698" ], "products": [ "species_10086707", "species_10086688", "species_10086705" ], "modifiers": [ [ "species_10086700", "catalyst" ] ], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1MAR8", "ENSBTAT00000084854", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "ENSBTAT00000024336", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10047210": { "compartment": "compartment_984", "id": "reaction_10047210", "reactome": "R-BTA-390649", "name": "CHRM1,3,5 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045758", "species_372533" ], "products": [ "species_10045760" ], "modifiers": [], "additional_components": [ "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383" ] }, "reaction_10047214": { "compartment": "compartment_984", "id": "reaction_10047214", "reactome": "R-BTA-390673", "name": "CHRM2,4 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046209", "species_372533" ], "products": [ "species_10046211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019534", "species_372533", "P41985", "ENSBTAT00000019534" ] }, "reaction_10047224": { "compartment": "compartment_984", "id": "reaction_10047224", "reactome": "R-BTA-390846", "name": "D2D3,4 bind to DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10046197" ], "products": [ "species_10046199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002768", "species_159362", "F1N454", "ENSBTAT00000002768" ] }, "reaction_10091556": { "compartment": "compartment_984", "id": "reaction_10091556", "reactome": "R-BTA-9656244", "name": "DRD2 binds DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10091552" ], "products": [ "species_10091554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014422", "F1N4I3", "ENSBTAT00000014422", "species_159362" ] }, "reaction_10047222": { "compartment": "compartment_984", "id": "reaction_10047222", "reactome": "R-BTA-390835", "name": "DRD1,5 bind DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10047218" ], "products": [ "species_10047220" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062955", "Q95136", "ENSBTAT00000062955", "species_159362" ] }, "reaction_10091929": { "compartment": "compartment_984", "id": "reaction_10091929", "reactome": "R-BTA-9693347", "name": "HTR1A binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091925", "species_114523" ], "products": [ "species_10091927" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054712", "species_209914", "F6Q2H9", "ENSBTAT00000054712" ] }, "reaction_10047256": { "compartment": "compartment_984", "id": "reaction_10047256", "reactome": "R-BTA-390931", "name": "5-HT4, 6 and 7 receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047252", "species_114523" ], "products": [ "species_10047254" ], "modifiers": [], "additional_components": [ "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575", "species_209914", "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10047236": { "compartment": "compartment_984", "id": "reaction_10047236", "reactome": "R-BTA-390929", "name": "HTR1 and 5A receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114523", "species_10046185" ], "products": [ "species_10046187" ], "modifiers": [], "additional_components": [ "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914" ] }, "reaction_10047238": { "compartment": "compartment_984", "id": "reaction_10047238", "reactome": "R-BTA-390930", "name": "5-HT2 receptor can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045782", "species_114523" ], "products": [ "species_10045784" ], "modifiers": [], "additional_components": [ "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796" ] }, "reaction_10047226": { "compartment": "compartment_984", "id": "reaction_10047226", "reactome": "R-BTA-390886", "name": "HRH4 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046191", "species_390899" ], "products": [ "species_10046193" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048201", "species_390899", "E1BBS2", "ENSBTAT00000048201" ] }, "reaction_10091825": { "compartment": "compartment_984", "id": "reaction_10091825", "reactome": "R-BTA-9692880", "name": "HRH3 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390899", "species_10091821" ], "products": [ "species_10091823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020802", "F1MML8", "ENSBTAT00000020802", "species_390899" ] }, "reaction_10047234": { "compartment": "compartment_984", "id": "reaction_10047234", "reactome": "R-BTA-390909", "name": "HRH2 binds hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047230", "species_390899" ], "products": [ "species_10047232" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061359", "species_390899", "E1BK27", "ENSBTAT00000061359" ] }, "reaction_10090968": { "compartment": "compartment_984", "id": "reaction_10090968", "reactome": "R-BTA-9611852", "name": "ADRB3 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051599" ], "products": [ "species_10051601" ], "modifiers": [ [ "species_10090958", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000085511", "CHEBI:28918", "species_209789", "A0A3Q1MQZ8", "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090925": { "compartment": "compartment_984", "id": "reaction_10090925", "reactome": "R-BTA-9609310", "name": "-blockers bind ADRB1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9609307", "species_10090921" ], "products": [ "species_10090923" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047212": { "compartment": "compartment_984", "id": "reaction_10047212", "reactome": "R-BTA-390663", "name": "ADRA2A,B,C bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10090960": { "compartment": "compartment_984", "id": "reaction_10090960", "reactome": "R-BTA-9611839", "name": "3-agonists bind ADRB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611836", "species_10051599" ], "products": [ "species_10090958" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090964": { "compartment": "compartment_984", "id": "reaction_10090964", "reactome": "R-BTA-9611851", "name": "ADRB2 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051593" ], "products": [ "species_10051595" ], "modifiers": [ [ "species_10090962", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047206": { "compartment": "compartment_984", "id": "reaction_10047206", "reactome": "R-BTA-390641", "name": "ADRA1A,B,D bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10045770" ], "products": [ "species_10045772" ], "modifiers": [ [ "species_10047204", "catalyst" ], [ "species_10047202", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443" ] }, "reaction_10047332": { "compartment": "compartment_984", "id": "reaction_10047332", "reactome": "R-BTA-391211", "name": "Trace amine-associated receptors can bind trace amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047328", "species_391200" ], "products": [ "species_10047330" ], "modifiers": [], "additional_components": [ "F1N0G5", "ENSBTAT00000054907", "species_391200", "F1N0G5", "ENSBTAT00000054907" ] }, "reaction_10083878": { "compartment": "compartment_876", "id": "reaction_10083878", "reactome": "R-BTA-8851298", "name": "GPR143 binds L-Dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851314", "species_10046122" ], "products": [ "species_10046124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008485", "G5E581", "ENSBTAT00000008485", "species_8851314" ] }, "reaction_10038450": { "compartment": "compartment_70101", "id": "reaction_10038450", "reactome": "R-BTA-162425", "name": "p-S295-PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10038447", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10036570": { "compartment": "compartment_70101", "id": "reaction_10036570", "reactome": "R-BTA-109699", "name": "PI3K-containing complexes phosphorylate PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10036567", "catalyst" ] ], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "G3XGD3", "ENSBTAT00000029946", "E1BHC1", "ENSBTAT00000016675", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LRU7", "ENSBTAT00000072473", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1M3Q3", "ENSBTAT00000073054", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10036607": { "compartment": "compartment_70101", "id": "reaction_10036607", "reactome": "R-BTA-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10036588" ], "products": [ "species_29370", "species_10036604" ], "modifiers": [ [ "species_10036596", "catalyst" ] ], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036590": { "compartment": "compartment_876", "id": "reaction_10036590", "reactome": "R-BTA-109700", "name": "AKT2 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036586" ], "products": [ "species_10036580", "species_10036588" ], "modifiers": [], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838" ] }, "reaction_10036598": { "compartment": "compartment_876", "id": "reaction_10036598", "reactome": "R-BTA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036594" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10035507": { "compartment": "compartment_70101", "id": "reaction_10035507", "reactome": "R-BTA-74736", "name": "GRB2-1:SOS1 binds p-IRS1,p-IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035503" ], "products": [ "species_10035505" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10035527": { "compartment": "compartment_70101", "id": "reaction_10035527", "reactome": "R-BTA-74737", "name": "p-Y-IRS1,p-Y-IRS2 bind PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10035503" ], "products": [ "species_10035525" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10055817": { "compartment": "compartment_12045", "id": "reaction_10055817", "reactome": "R-BTA-983424", "name": "Budding of COPII coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055815" ], "products": [ "species_10055805" ], "modifiers": [], "additional_components": [ "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10043659": { "compartment": "compartment_12045", "id": "reaction_10043659", "reactome": "R-BTA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580" ], "products": [ "species_10043657" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055819": { "compartment": "compartment_12045", "id": "reaction_10055819", "reactome": "R-BTA-983426", "name": "Capturing cargo and formation of prebudding complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054858", "species_10043657" ], "products": [ "species_10055813" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055821": { "compartment": "compartment_876", "id": "reaction_10055821", "reactome": "R-BTA-983427", "name": "Expression of peptide bound class I MHC on cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055781" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10087807": { "compartment": "compartment_453088", "id": "reaction_10087807", "reactome": "R-BTA-8951499", "name": "Loading of antigenic peptides on to class I MHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055472", "species_983033" ], "products": [ "species_10055474" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "species_1236727", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10054866": { "compartment": "compartment_453088", "id": "reaction_10054866", "reactome": "R-BTA-983138", "name": "Transport of MHC heterotrimer to ER exit site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054864" ], "products": [ "species_10054862", "species_10054858" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q5E9F1", "ENSBTAT00000068015", "Q5E9F1", "ENSBTAT00000068015", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727" ] }, "reaction_10055444": { "compartment": "compartment_17957", "id": "reaction_10055444", "reactome": "R-BTA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10055441", "catalyst" ] ], "additional_components": [ "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10055460": { "compartment": "compartment_17957", "id": "reaction_10055460", "reactome": "R-BTA-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_8943716", "species_983033" ], "modifiers": [ [ "species_10055457", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078466" ] }, "reaction_10055783": { "compartment": "compartment_13945", "id": "reaction_10055783", "reactome": "R-BTA-983421", "name": "Journey of cargo through Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055715" ], "products": [ "species_10055781" ], "modifiers": [], "additional_components": [ "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10039485": { "compartment": "compartment_947587", "id": "reaction_10039485", "reactome": "R-BTA-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10036954" ], "products": [ "species_29438", "species_10037043" ], "modifiers": [ [ "species_10036952", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160" ] }, "reaction_10037641": { "compartment": "compartment_70101", "id": "reaction_10037641", "reactome": "R-BTA-139898", "name": "Caspase-8 activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037731": { "compartment": "compartment_70101", "id": "reaction_10037731", "reactome": "R-BTA-139920", "name": "Translocation of tBID to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037729" ], "products": [ "species_10037269" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737" ] }, "reaction_10037618": { "compartment": "compartment_70101", "id": "reaction_10037618", "reactome": "R-BTA-139893", "name": "Granzyme-B activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000013262" ] }, "reaction_10038007": { "compartment": "compartment_70101", "id": "reaction_10038007", "reactome": "R-BTA-141367", "name": "Myristoylation of tBID by NMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037611" ], "products": [ "species_10037729" ], "modifiers": [ [ "species_10038004", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000007950" ] }, "reaction_10049615": { "compartment": "compartment_984", "id": "reaction_10049615", "reactome": "R-BTA-444171", "name": "Receptor FFAR2 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046048", "species_444210" ], "products": [ "species_10046050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008619", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJV9", "ENSBTAT00000008619" ] }, "reaction_10049617": { "compartment": "compartment_984", "id": "reaction_10049617", "reactome": "R-BTA-444202", "name": "Receptor FFAR1 binds free fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10049585": { "compartment": "compartment_984", "id": "reaction_10049585", "reactome": "R-BTA-444047", "name": "Receptor FFAR3 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046054", "species_444074" ], "products": [ "species_10046056" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053502", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502" ] }, "reaction_10067360": { "compartment": "compartment_876", "id": "reaction_10067360", "reactome": "R-BTA-3296304", "name": "GPR31 is a receptor for 12(S)-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296298", "species_10046489" ], "products": [ "species_10046491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019274", "F1N1J4", "ENSBTAT00000019274", "species_3296298" ] }, "reaction_10041453": { "compartment": "compartment_984", "id": "reaction_10041453", "reactome": "R-BTA-194308", "name": "VEGF-C,D bind to VEGFR3 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041447", "species_10041443" ], "products": [ "species_10041451" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613", "F1MHP5", "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10041463": { "compartment": "compartment_984", "id": "reaction_10041463", "reactome": "R-BTA-194310", "name": "VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041443", "species_10041457" ], "products": [ "species_10041461" ], "modifiers": [], "additional_components": [ "Q9XS50", "ENSBTAT00000019613", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10040328": { "compartment": "compartment_70101", "id": "reaction_10040328", "reactome": "R-BTA-177944", "name": "Activation of SHP2 through the binding to phospho-Gab1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10040245" ], "products": [ "species_10040247" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040299": { "compartment": "compartment_70101", "id": "reaction_10040299", "reactome": "R-BTA-177935", "name": "SHP2 dephosphorylates Tyr 992 on EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040297" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040267": { "compartment": "compartment_70101", "id": "reaction_10040267", "reactome": "R-BTA-177926", "name": "Dephosphorylation of PAG by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040263", "species_29356" ], "products": [ "species_29372", "species_10040265" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067689", "ENSBTAT00000067689", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040254": { "compartment": "compartment_70101", "id": "reaction_10040254", "reactome": "R-BTA-177924", "name": "Dephosphorylation of Gab1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040251" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040277": { "compartment": "compartment_70101", "id": "reaction_10040277", "reactome": "R-BTA-177930", "name": "GAB1 phosphorylation by EGFR kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040271" ], "products": [ "species_10040245", "species_29370" ], "modifiers": [ [ "species_10040271", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10043129": { "compartment": "compartment_876", "id": "reaction_10043129", "reactome": "R-BTA-201677", "name": "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043120", "species_113592" ], "products": [ "species_10043126", "species_29370" ], "modifiers": [ [ "species_10043120", "catalyst" ] ], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1N1K8", "ENSBTAT00000007756", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10071320": { "compartment": "compartment_70101", "id": "reaction_10071320", "reactome": "R-BTA-5323526", "name": "FRAT proteins bind GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041625" ], "products": [ "species_10041627" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10059152": { "compartment": "compartment_70101", "id": "reaction_10059152", "reactome": "R-BTA-1504186", "name": "DVL recruits GSK3beta:AXIN1 to the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043061", "species_10043118" ], "products": [ "species_10043120" ], "modifiers": [], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10083835": { "compartment": "compartment_984", "id": "reaction_10083835", "reactome": "R-BTA-8850831", "name": "KLK5 cleaves and activates KLK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10083828" ], "products": [ "species_10083830", "species_10083832" ], "modifiers": [ [ "species_10083733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000070524" ] }, "reaction_10083741": { "compartment": "compartment_984", "id": "reaction_10083741", "reactome": "R-BTA-8849638", "name": "Dissociation of the SPINK5:KLK5 complex at low pH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083739" ], "products": [ "species_10083733", "species_10083737" ], "modifiers": [ [ "species_351626", "catalyst" ] ], "additional_components": [ "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524", "ENSBTAT00000070524", "ENSBTAT00000025479" ] }, "reaction_10083743": { "compartment": "compartment_984", "id": "reaction_10083743", "reactome": "R-BTA-8849646", "name": "SPINK5(490-624) binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083737" ], "products": [ "species_10083739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000025479", "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10083824": { "compartment": "compartment_984", "id": "reaction_10083824", "reactome": "R-BTA-8850818", "name": "SPINK9 binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083820" ], "products": [ "species_10083822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000081553", "A0A3Q1NK79", "ENSBTAT00000081553", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10077943": { "compartment": "compartment_984", "id": "reaction_10077943", "reactome": "R-BTA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10077940", "catalyst" ] ], "additional_components": [ "E1BA50", "ENSBTAT00000017778", "G3MVZ9", "ENSBTAT00000034704" ] }, "reaction_10084466": { "compartment": "compartment_70101", "id": "reaction_10084466", "reactome": "R-BTA-8857577", "name": "LINC01139 facilitates PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084458" ], "products": [ "species_29370", "species_10084463" ], "modifiers": [ [ "species_10084458", "catalyst" ] ], "additional_components": [ "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10090009": { "compartment": "compartment_876", "id": "reaction_10090009", "reactome": "R-BTA-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090005", "species_10089989" ], "products": [ "species_10090007" ], "modifiers": [], "additional_components": [ "A0A3Q1MD15", "ENSBTAT00000079650", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MD15", "ENSBTAT00000079650" ] }, "reaction_10091896": { "compartment": "compartment_17906", "id": "reaction_10091896", "reactome": "R-BTA-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091892", "species_10091882" ], "products": [ "species_10091894" ], "modifiers": [], "additional_components": [ "F1MY55", "ENSBTAT00000023513", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1MY55", "ENSBTAT00000023513" ] }, "reaction_10090011": { "compartment": "compartment_876", "id": "reaction_10090011", "reactome": "R-BTA-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10089989" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091884": { "compartment": "compartment_876", "id": "reaction_10091884", "reactome": "R-BTA-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091882" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091916": { "compartment": "compartment_20699", "id": "reaction_10091916", "reactome": "R-BTA-9693250", "name": "RHOD binds effectors at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091900", "species_10091912" ], "products": [ "species_10091914" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MZP2", "ENSBTAT00000081390", "A0A3Q1MZP2", "ENSBTAT00000081390", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091902": { "compartment": "compartment_876", "id": "reaction_10091902", "reactome": "R-BTA-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091900" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10089985": { "compartment": "compartment_876", "id": "reaction_10089985", "reactome": "R-BTA-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10089969" ], "products": [ "species_29372", "species_10089965" ], "modifiers": [ [ "species_10089982", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089972": { "compartment": "compartment_876", "id": "reaction_10089972", "reactome": "R-BTA-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089965" ], "products": [ "species_29420", "species_10089969" ], "modifiers": [ [ "species_10089965", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29420", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420" ] }, "reaction_10091878": { "compartment": "compartment_70101", "id": "reaction_10091878", "reactome": "R-BTA-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091874", "species_10089969" ], "products": [ "species_10091876" ], "modifiers": [], "additional_components": [ "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009" ] }, "reaction_10057177": { "compartment": "compartment_876", "id": "reaction_10057177", "reactome": "R-BTA-1250357", "name": "SHC1 binds P-ERBB4 isoform dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057163", "species_10035544" ], "products": [ "species_10057170" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057188": { "compartment": "compartment_876", "id": "reaction_10057188", "reactome": "R-BTA-1250380", "name": "Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057172", "species_10035491" ], "products": [ "species_10057186" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057175": { "compartment": "compartment_876", "id": "reaction_10057175", "reactome": "R-BTA-1250348", "name": "Phosphorylation of SHC1 by ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057170", "species_113592" ], "products": [ "species_10057172", "species_29370" ], "modifiers": [ [ "species_10057170", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057191": { "compartment": "compartment_70101", "id": "reaction_10057191", "reactome": "R-BTA-1250383", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057186", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10083712": { "compartment": "compartment_20699", "id": "reaction_10083712", "reactome": "R-BTA-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_8848483" ], "products": [ "species_429785", "species_76194" ], "modifiers": [ [ "species_10083709", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087371" ] }, "reaction_10083004": { "compartment": "compartment_20699", "id": "reaction_10083004", "reactome": "R-BTA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10082997" ], "products": [ "species_29420", "species_10083001" ], "modifiers": [ [ "species_10082997", "catalyst" ] ], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10083006": { "compartment": "compartment_20699", "id": "reaction_10083006", "reactome": "R-BTA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082993" ], "products": [ "species_10082995" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082999": { "compartment": "compartment_20699", "id": "reaction_10082999", "reactome": "R-BTA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082995" ], "products": [ "species_10082997" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10049867": { "compartment": "compartment_12045", "id": "reaction_10049867", "reactome": "R-BTA-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_29420", "species_449283" ], "modifiers": [ [ "species_10049864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002836" ] }, "reaction_10049851": { "compartment": "compartment_12045", "id": "reaction_10049851", "reactome": "R-BTA-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10049848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003187" ] }, "reaction_10049789": { "compartment": "compartment_17957", "id": "reaction_10049789", "reactome": "R-BTA-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449298" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10049782", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000032212", "ENSBTAT00000000147" ] }, "reaction_10049811": { "compartment": "compartment_17957", "id": "reaction_10049811", "reactome": "R-BTA-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449312" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10049808", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064352", "ENSBTAT00000000147" ] }, "reaction_10049858": { "compartment": "compartment_17957", "id": "reaction_10049858", "reactome": "R-BTA-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449315" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10082941": { "compartment": "compartment_70101", "id": "reaction_10082941", "reactome": "R-BTA-6810464", "name": "NUDT14 hydrolyses UDP-Glc to G1P and UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410" ], "products": [ "species_29548", "species_109402" ], "modifiers": [ [ "species_10082938", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063951" ] }, "reaction_10077816": { "compartment": "compartment_70101", "id": "reaction_10077816", "reactome": "R-BTA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10077800": { "compartment": "compartment_70101", "id": "reaction_10077800", "reactome": "R-BTA-6787533", "name": "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_6787542" ], "products": [ "species_111294", "species_742368" ], "modifiers": [ [ "species_10077797", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055149" ] }, "reaction_10077823": { "compartment": "compartment_70101", "id": "reaction_10077823", "reactome": "R-BTA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10077820", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015992" ] }, "reaction_10077807": { "compartment": "compartment_70101", "id": "reaction_10077807", "reactome": "R-BTA-6787540", "name": "FUK phosphorylates beta-Fuc to Fuc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6787678" ], "products": [ "species_29370", "species_6787542" ], "modifiers": [ [ "species_10077804", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085459" ] }, "reaction_10077826": { "compartment": "compartment_70101", "id": "reaction_10077826", "reactome": "R-BTA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10049831": { "compartment": "compartment_70101", "id": "reaction_10049831", "reactome": "R-BTA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10049828", "catalyst" ] ], "additional_components": [ "Q0VC17", "ENSBTAT00000076692", "Q3SZJ9", "ENSBTAT00000001888" ] }, "reaction_10069368": { "compartment": "compartment_70101", "id": "reaction_10069368", "reactome": "R-BTA-4085021", "name": "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_162756" ], "products": [ "species_110096", "species_4085214" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069320": { "compartment": "compartment_70101", "id": "reaction_10069320", "reactome": "R-BTA-4084976", "name": "NANS converts ManNAc-6-P to Neu5Ac-9-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085225", "species_29492" ], "products": [ "species_29372", "species_4085390" ], "modifiers": [ [ "species_10069317", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025318" ] }, "reaction_10069371": { "compartment": "compartment_70101", "id": "reaction_10069371", "reactome": "R-BTA-4085028", "name": "GNE phosphorylates ManNAc to ManNAc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_4085214" ], "products": [ "species_29370", "species_4085225" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069357": { "compartment": "compartment_70101", "id": "reaction_10069357", "reactome": "R-BTA-4084989", "name": "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085390" ], "products": [ "species_428633", "species_29372" ], "modifiers": [ [ "species_10069354", "catalyst" ] ], "additional_components": [ "A7YWM8", "ENSBTAT00000000918", "species_29926" ] }, "reaction_10069373": { "compartment": "compartment_70101", "id": "reaction_10069373", "reactome": "R-BTA-4085029", "name": "NEU2 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088202" ], "products": [ "species_428633", "species_4088123" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "species_4086294", "species_4086341", "species_4087982", "species_4086277", "species_4088006", "species_4086285", "species_4086301", "ENSBTAT00000027552" ] }, "reaction_10069359": { "compartment": "compartment_70101", "id": "reaction_10069359", "reactome": "R-BTA-4084994", "name": "NEU3 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088088" ], "products": [ "species_428633", "species_4088103" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "species_4086277", "species_4087982", "species_4088006", "species_4086285", "ENSBTAT00000036738" ] }, "reaction_10048958": { "compartment": "compartment_17938", "id": "reaction_10048958", "reactome": "R-BTA-428585", "name": "SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_428639" ], "products": [ "species_428633", "species_70106" ], "modifiers": [ [ "species_10048955", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061225" ] }, "reaction_10069329": { "compartment": "compartment_20699", "id": "reaction_10069329", "reactome": "R-BTA-4084978", "name": "ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4088006" ], "products": [ "species_727810", "species_4087982" ], "modifiers": [ [ "species_10069326", "catalyst" ] ], "additional_components": [ "A0A3Q1N8K2", "ENSBTAT00000074715", "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10051554": { "compartment": "compartment_20699", "id": "reaction_10051554", "reactome": "R-BTA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10051551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018680" ] }, "reaction_10069346": { "compartment": "compartment_20699", "id": "reaction_10069346", "reactome": "R-BTA-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086301" ], "products": [ "species_4086341", "species_727810" ], "modifiers": [ [ "species_10069343", "catalyst" ] ], "additional_components": [ "F1MXN8", "ENSBTAT00000009616", "G3N3B2", "ENSBTAT00000063122", "A0A452DJH9", "ENSBTAT00000061027", "A0A3Q1LRX1", "ENSBTAT00000078008", "F1N6V7", "ENSBTAT00000034693" ] }, "reaction_10069348": { "compartment": "compartment_17963", "id": "reaction_10069348", "reactome": "R-BTA-4084984", "name": "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_4086277", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10069382": { "compartment": "compartment_20699", "id": "reaction_10069382", "reactome": "R-BTA-4085033", "name": "ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_727810", "species_4086294" ], "modifiers": [ [ "species_10069379", "catalyst" ] ], "additional_components": [ "A0A3Q1M347", "ENSBTAT00000083430", "A5D7T4", "ENSBTAT00000070130" ] }, "reaction_10069498": { "compartment": "compartment_12045", "id": "reaction_10069498", "reactome": "R-BTA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10069495", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855" ] }, "reaction_10049818": { "compartment": "compartment_12045", "id": "reaction_10049818", "reactome": "R-BTA-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449744" ], "products": [ "species_29372", "species_449299" ], "modifiers": [ [ "species_10049815", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023834" ] }, "reaction_10049804": { "compartment": "compartment_12045", "id": "reaction_10049804", "reactome": "R-BTA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10049801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014016" ] }, "reaction_10040933": { "compartment": "compartment_70101", "id": "reaction_10040933", "reactome": "R-BTA-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29372", "species_29370", "species_113528", "species_191362" ], "modifiers": [ [ "species_10040930", "catalyst" ] ], "additional_components": [ "Q0P570", "ENSBTAT00000015994" ] }, "reaction_10049797": { "compartment": "compartment_12045", "id": "reaction_10049797", "reactome": "R-BTA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10049794", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070574" ] }, "reaction_10049844": { "compartment": "compartment_12045", "id": "reaction_10049844", "reactome": "R-BTA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10049841", "catalyst" ] ], "additional_components": [ "F1MU60", "ENSBTAT00000006020", "A0A3Q1MW72", "ENSBTAT00000076761" ] }, "reaction_10049860": { "compartment": "compartment_17957", "id": "reaction_10049860", "reactome": "R-BTA-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449371", "species_449311" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10056074": { "compartment": "compartment_20699", "id": "reaction_10056074", "reactome": "R-BTA-1022133", "name": "ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10056071", "catalyst" ] ], "additional_components": [ "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10056061": { "compartment": "compartment_20699", "id": "reaction_10056061", "reactome": "R-BTA-1022129", "name": "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075324" ] }, "reaction_10054431": { "compartment": "compartment_20699", "id": "reaction_10054431", "reactome": "R-BTA-975903", "name": "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981616" ], "modifiers": [ [ "species_10054428", "catalyst" ] ], "additional_components": [ "E1BNB2", "ENSBTAT00000014809", "A6QQ63", "ENSBTAT00000049734" ] }, "reaction_10054467": { "compartment": "compartment_20699", "id": "reaction_10054467", "reactome": "R-BTA-975919", "name": "Addition of galactose by beta 4-galactosyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_975910" ], "products": [ "species_981618" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10054418": { "compartment": "compartment_20699", "id": "reaction_10054418", "reactome": "R-BTA-975902", "name": "ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083430" ] }, "reaction_10054438": { "compartment": "compartment_20699", "id": "reaction_10054438", "reactome": "R-BTA-975916", "name": "Addition of GlcNAc to position 5 by MGAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981617" ], "modifiers": [ [ "species_10054435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084669" ] }, "reaction_10054474": { "compartment": "compartment_17963", "id": "reaction_10054474", "reactome": "R-BTA-975926", "name": "Addition of a bifurcating GlcNAc to the N-glycan by MGAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981613" ], "modifiers": [ [ "species_10054471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016591" ] }, "reaction_10054411": { "compartment": "compartment_20699", "id": "reaction_10054411", "reactome": "R-BTA-975829", "name": "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975819" ], "products": [ "species_205687", "species_975822" ], "modifiers": [ [ "species_10054408", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048092" ] }, "reaction_10076415": { "compartment": "compartment_161320", "id": "reaction_10076415", "reactome": "R-BTA-5693807", "name": "FUCA1 hydrolyses NGP:1,6-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6784247" ], "products": [ "species_6784248", "species_6784249" ], "modifiers": [ [ "species_10076412", "catalyst" ] ], "additional_components": [ "Q2KIM0", "ENSBTAT00000042970" ] }, "reaction_10077710": { "compartment": "compartment_20699", "id": "reaction_10077710", "reactome": "R-BTA-6786034", "name": "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10077694" ], "products": [ "species_10077703", "species_742343" ], "modifiers": [ [ "species_10077707", "catalyst" ] ], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000064164" ] }, "reaction_10077717": { "compartment": "compartment_20699", "id": "reaction_10077717", "reactome": "R-BTA-6786048", "name": "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_6786371" ], "products": [ "species_742343", "species_6786380" ], "modifiers": [ [ "species_10077714", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082120" ] }, "reaction_10076422": { "compartment": "compartment_17963", "id": "reaction_10076422", "reactome": "R-BTA-5693925", "name": "FUT3 transfers L-fucose to Gal1,3GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693930", "species_205683" ], "products": [ "species_5693933", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10076696": { "compartment": "compartment_12045", "id": "reaction_10076696", "reactome": "R-BTA-5694433", "name": "MIA2 binds PREB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076692", "species_10043646" ], "products": [ "species_10076694" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078548", "ENSBTAT00000009307", "E1BL12", "ENSBTAT00000009307", "A0A3Q1LM15", "ENSBTAT00000078548" ] }, "reaction_10076586": { "compartment": "compartment_12045", "id": "reaction_10076586", "reactome": "R-BTA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043590", "species_10043594", "species_10043592" ], "products": [ "species_10043596" ], "modifiers": [], "additional_components": [ "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "ENSBTAT00000004831", "ENSBTAT00000004721", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561" ] }, "reaction_10076590": { "compartment": "compartment_12045", "id": "reaction_10076590", "reactome": "R-BTA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10043651", "species_10043594" ], "products": [ "species_10076588" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "ENSBTAT00000043111", "ENSBTAT00000004831", "A6QNT8", "ENSBTAT00000043111", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10076706": { "compartment": "compartment_12045", "id": "reaction_10076706", "reactome": "R-BTA-5694442", "name": "CNIH2,3 bind GRIA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043622", "species_10043618" ], "products": [ "species_10043624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082647", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647" ] }, "reaction_10076708": { "compartment": "compartment_12045", "id": "reaction_10076708", "reactome": "R-BTA-5694445", "name": "CNIH1 binds TFGA and AREG precursors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043606", "species_10043600" ], "products": [ "species_10043608" ], "modifiers": [], "additional_components": [ "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "ENSBTAT00000025975", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129" ] }, "reaction_10076775": { "compartment": "compartment_12045", "id": "reaction_10076775", "reactome": "R-BTA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580", "species_10043626" ], "products": [ "species_10043628" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076584": { "compartment": "compartment_13959", "id": "reaction_10076584", "reactome": "R-BTA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10076577" ], "products": [ "species_10076581", "species_29420" ], "modifiers": [ [ "species_10076577", "catalyst" ] ], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10076635": { "compartment": "compartment_70101", "id": "reaction_10076635", "reactome": "R-BTA-5694421", "name": "PP6 dephosphorylates SEC24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10076618" ], "products": [ "species_29372", "species_10043653" ], "modifiers": [ [ "species_10076632", "catalyst" ] ], "additional_components": [ "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "E1BN43", "ENSBTAT00000034553", "Q2KIC7", "ENSBTAT00000010568", "G3N214", "ENSBTAT00000066016" ] }, "reaction_10076778": { "compartment": "compartment_70101", "id": "reaction_10076778", "reactome": "R-BTA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043628" ], "products": [ "species_10043655", "species_29372", "species_10043626", "species_10043642" ], "modifiers": [ [ "species_10043628", "catalyst" ] ], "additional_components": [ "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076698": { "compartment": "compartment_13959", "id": "reaction_10076698", "reactome": "R-BTA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076575", "species_10076493", "species_10076537" ], "products": [ "species_10076577" ], "modifiers": [], "additional_components": [ "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10043649": { "compartment": "compartment_70101", "id": "reaction_10043649", "reactome": "R-BTA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043642" ], "products": [ "species_29420", "species_10043580" ], "modifiers": [ [ "species_10043646", "catalyst" ] ], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "ENSBTAT00000009307" ] }, "reaction_10083377": { "compartment": "compartment_6791047", "id": "reaction_10083377", "reactome": "R-BTA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082020", "species_10083373" ], "products": [ "species_10083375" ], "modifiers": [], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10076736": { "compartment": "compartment_6791047", "id": "reaction_10076736", "reactome": "R-BTA-5694446", "name": "BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076704", "species_10076667" ], "products": [ "species_10076596", "species_10076677", "species_10076734", "species_10076602" ], "modifiers": [], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "P41541", "ENSBTAT00000022642", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "P41541", "ENSBTAT00000022642" ] }, "reaction_10076610": { "compartment": "compartment_20699", "id": "reaction_10076610", "reactome": "R-BTA-5694418", "name": "RAB1:GTP binds USO1 and GORASP1:GOLGA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076596", "species_10076581", "species_10076602" ], "products": [ "species_10076608" ], "modifiers": [], "additional_components": [ "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10083380": { "compartment": "compartment_6791047", "id": "reaction_10083380", "reactome": "R-BTA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083375" ], "products": [ "species_10083373", "species_10076493" ], "modifiers": [ [ "species_10083375", "catalyst" ] ], "additional_components": [ "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10082026": { "compartment": "compartment_6791047", "id": "reaction_10082026", "reactome": "R-BTA-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082020", "species_10076602" ], "products": [ "species_10082024" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082045": { "compartment": "compartment_6791047", "id": "reaction_10082045", "reactome": "R-BTA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082036", "species_113592" ], "products": [ "species_29370", "species_10082042" ], "modifiers": [ [ "species_10082036", "catalyst" ] ], "additional_components": [ "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10082038": { "compartment": "compartment_6791047", "id": "reaction_10082038", "reactome": "R-BTA-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082024" ], "products": [ "species_10082036" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10053337": { "compartment": "compartment_20699", "id": "reaction_10053337", "reactome": "R-BTA-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "CHEBI:60629", "CHEBI:60628", "CHEBI:60627", "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053339": { "compartment": "compartment_20699", "id": "reaction_10053339", "reactome": "R-BTA-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053317": { "compartment": "compartment_20699", "id": "reaction_10053317", "reactome": "R-BTA-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053324": { "compartment": "compartment_17963", "id": "reaction_10053324", "reactome": "R-BTA-964759", "name": "Alternative endo-mannosidase I route", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964754" ], "products": [ "species_964744", "species_964746" ], "modifiers": [ [ "species_10053321", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006614" ] }, "reaction_10053331": { "compartment": "compartment_20699", "id": "reaction_10053331", "reactome": "R-BTA-964768", "name": "Addition of GlcNAc to the glycan on the A arm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_964740" ], "products": [ "species_964837", "species_205687" ], "modifiers": [ [ "species_10053328", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066191" ] }, "reaction_10084373": { "compartment": "compartment_984", "id": "reaction_10084373", "reactome": "R-BTA-8855711", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855720", "species_10084369" ], "products": [ "species_10084371" ], "modifiers": [], "additional_components": [ "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "species_8855720" ] }, "reaction_10056058": { "compartment": "compartment_70101", "id": "reaction_10056058", "reactome": "R-BTA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056054" ], "products": [ "species_10056056" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "CHEBI:60627", "CHEBI:60628", "species_915149", "CHEBI:60629", "species_964740", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10089391": { "compartment": "compartment_5460", "id": "reaction_10089391", "reactome": "R-BTA-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089384" ], "products": [], "modifiers": [ [ "species_10089388", "catalyst" ] ], "additional_components": [ "Q02372", "ENSBTAT00000000100", "ENSBTAT00000046212" ] }, "reaction_10056912": { "compartment": "compartment_24339", "id": "reaction_10056912", "reactome": "R-BTA-1236955", "name": "Movement of clathrin coated vesicles into early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056833" ], "products": [ "species_10056803" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056835": { "compartment": "compartment_24339", "id": "reaction_10056835", "reactome": "R-BTA-1236941", "name": "Internalization of receptor bound antigen into clathrin coted vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056819" ], "products": [ "species_10056833" ], "modifiers": [], "additional_components": [ "species_1236715", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056805": { "compartment": "compartment_171043", "id": "reaction_10056805", "reactome": "R-BTA-1236940", "name": "Exogenous soluble antigen targeted to more stable early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056803" ], "products": [ "species_1236715", "species_10056801" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10087823": { "compartment": "compartment_6791047", "id": "reaction_10087823", "reactome": "R-BTA-8951595", "name": "CALR, TAP, TAPBP dissociate from SEC22B:STX4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084863" ], "products": [ "species_10087813", "species_10087809", "species_10087821", "species_10087819" ], "modifiers": [], "additional_components": [ "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899", "A0A3Q1MMA1", "ENSBTAT00000066705", "A0A452DIB2", "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10084865": { "compartment": "compartment_6791047", "id": "reaction_10084865", "reactome": "R-BTA-8863858", "name": "SEC22B, CALR, STX4, TAP and TAPBP bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084853", "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "products": [ "species_10084863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10084867": { "compartment": "compartment_6791047", "id": "reaction_10084867", "reactome": "R-BTA-8863914", "name": "Transport of SEC22B, TAP and PLC from ER to ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10055441", "species_10055470", "species_10055468" ], "products": [ "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10056982": { "compartment": "compartment_1222693", "id": "reaction_10056982", "reactome": "R-BTA-1236965", "name": "Export of peptide loaded MHC class I complex to PM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056980" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056910": { "compartment": "compartment_171062", "id": "reaction_10056910", "reactome": "R-BTA-1236954", "name": "Trimming of peptides by IRAP in endocytic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236722" ], "products": [ "species_8943711", "species_1236727" ], "modifiers": [ [ "species_10056907", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10056914": { "compartment": "compartment_876", "id": "reaction_10056914", "reactome": "R-BTA-1236964", "name": "Translocation of peptide bound MHC class I complex to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056901" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056903": { "compartment": "compartment_171043", "id": "reaction_10056903", "reactome": "R-BTA-1236943", "name": "Loading of antigen peptide onto MHC class I molecule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056899", "species_1236727" ], "products": [ "species_10056901" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10057004": { "compartment": "compartment_263698", "id": "reaction_10057004", "reactome": "R-BTA-1236967", "name": "Alkalization of the phagosomal lumen by NOX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_2000347" ], "products": [ "species_2000345", "species_2000349", "species_2000348" ], "modifiers": [ [ "species_10057001", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657" ] }, "reaction_10041962": { "compartment": "compartment_876", "id": "reaction_10041962", "reactome": "R-BTA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10041959", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042889" ] }, "reaction_10041955": { "compartment": "compartment_70101", "id": "reaction_10041955", "reactome": "R-BTA-198813", "name": "GSTO dimers reduce DeHA to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_198827" ], "products": [ "species_198816", "species_111745" ], "modifiers": [ [ "species_10041952", "catalyst" ] ], "additional_components": [ "E1BED9", "ENSBTAT00000005211" ] }, "reaction_10041975": { "compartment": "compartment_876", "id": "reaction_10041975", "reactome": "R-BTA-198870", "name": "SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198836", "species_74113" ], "products": [ "species_83910", "species_198816" ], "modifiers": [ [ "species_10041972", "catalyst" ] ], "additional_components": [ "E1BI45", "ENSBTAT00000010823", "E1BP61", "ENSBTAT00000083275" ] }, "reaction_10083656": { "compartment": "compartment_70101", "id": "reaction_10083656", "reactome": "R-BTA-8848930", "name": "PTK6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083480" ], "products": [ "species_10083654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122" ] }, "reaction_10083672": { "compartment": "compartment_7660", "id": "reaction_10083672", "reactome": "R-BTA-8848975", "name": "PTK6 phosphorylates KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10083662" ], "products": [ "species_10083654", "species_113582", "species_10083669" ], "modifiers": [ [ "species_10083662", "catalyst" ] ], "additional_components": [ "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083676": { "compartment": "compartment_7660", "id": "reaction_10083676", "reactome": "R-BTA-8848993", "name": "Phosphorylated KHDRBS1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083669" ], "products": [ "species_10083674" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016581", "ENSBTAT00000016581" ] }, "reaction_10083664": { "compartment": "compartment_7660", "id": "reaction_10083664", "reactome": "R-BTA-8848939", "name": "PTK6 binds KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083654", "species_10083660" ], "products": [ "species_10083662" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10037748": { "compartment": "compartment_17957", "id": "reaction_10037748", "reactome": "R-BTA-140355", "name": "Arachidonic acid is oxidised to PGG2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10037751": { "compartment": "compartment_17957", "id": "reaction_10037751", "reactome": "R-BTA-140359", "name": "PGG2 is reduced to PGH2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10063448": { "compartment": "compartment_17957", "id": "reaction_10063448", "reactome": "R-BTA-2046095", "name": "Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046060", "species_113601" ], "products": [ "species_2046048", "species_113519", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063450": { "compartment": "compartment_12045", "id": "reaction_10063450", "reactome": "R-BTA-2046096", "name": "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046063" ], "products": [ "species_194653", "species_113519", "species_2046042" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063452": { "compartment": "compartment_17957", "id": "reaction_10063452", "reactome": "R-BTA-2046097", "name": "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046048", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046050" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063454": { "compartment": "compartment_12045", "id": "reaction_10063454", "reactome": "R-BTA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063442": { "compartment": "compartment_17957", "id": "reaction_10063442", "reactome": "R-BTA-2046092", "name": "Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046045" ], "products": [ "species_194653", "species_113519", "species_2046053" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063413": { "compartment": "compartment_12045", "id": "reaction_10063413", "reactome": "R-BTA-2046083", "name": "Elongation of arachidonyl-CoA to docosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046053", "species_113601" ], "products": [ "species_113519", "species_162743", "species_159751", "species_2046060" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063444": { "compartment": "compartment_12045", "id": "reaction_10063444", "reactome": "R-BTA-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_5228339", "species_2046055", "species_211606" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063446": { "compartment": "compartment_17957", "id": "reaction_10063446", "reactome": "R-BTA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063437": { "compartment": "compartment_17957", "id": "reaction_10063437", "reactome": "R-BTA-2046089", "name": "Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046051", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046059" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063420": { "compartment": "compartment_12045", "id": "reaction_10063420", "reactome": "R-BTA-2046084", "name": "Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046062" ], "products": [ "species_194653", "species_113519", "species_2046052" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063425": { "compartment": "compartment_12045", "id": "reaction_10063425", "reactome": "R-BTA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063456": { "compartment": "compartment_12045", "id": "reaction_10063456", "reactome": "R-BTA-2046100", "name": "Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046059", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046057", "species_162743", "species_159751" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063440": { "compartment": "compartment_17957", "id": "reaction_10063440", "reactome": "R-BTA-2046090", "name": "Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046057", "species_113601" ], "products": [ "species_113519", "species_2046065", "species_113564", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063570": { "compartment": "compartment_17951", "id": "reaction_10063570", "reactome": "R-BTA-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10063573": { "compartment": "compartment_17951", "id": "reaction_10063573", "reactome": "R-BTA-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_2066762" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10063428": { "compartment": "compartment_17957", "id": "reaction_10063428", "reactome": "R-BTA-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_426639", "species_211606", "species_2046047" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063430": { "compartment": "compartment_17957", "id": "reaction_10063430", "reactome": "R-BTA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10033912": { "compartment": "compartment_5460", "id": "reaction_10033912", "reactome": "R-BTA-71031", "name": "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70843", "species_113593", "species_29376" ], "products": [ "species_113548", "species_113581", "species_71019" ], "modifiers": [ [ "species_10033909", "catalyst" ] ], "additional_components": [ "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10033896": { "compartment": "compartment_5460", "id": "reaction_10033896", "reactome": "R-BTA-71020", "name": "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71019" ], "products": [ "species_71009" ], "modifiers": [ [ "species_10033893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000049741" ] }, "reaction_10033889": { "compartment": "compartment_5460", "id": "reaction_10033889", "reactome": "R-BTA-71010", "name": "MUT isomerises L-MM-CoA to SUCC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71009" ], "products": [ "species_70958" ], "modifiers": [ [ "species_10033884", "catalyst" ] ], "additional_components": [ "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10075631": { "compartment": "compartment_5460", "id": "reaction_10075631", "reactome": "R-BTA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10075628", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_30495", "CHEBI:59554", "E1BA10", "ENSBTAP00000020594", "A6QQA9", "ENSBTAT00000074250", "F1N234", "ENSBTAT00000074250", "E1BAC0", "ENSBTAT00000000922" ] }, "reaction_10036029": { "compartment": "compartment_5460", "id": "reaction_10036029", "reactome": "R-BTA-77331", "name": "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77330" ], "products": [ "species_113529", "species_29362", "species_77328" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036038": { "compartment": "compartment_5460", "id": "reaction_10036038", "reactome": "R-BTA-77338", "name": "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77337" ], "products": [ "species_77332", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036027": { "compartment": "compartment_5460", "id": "reaction_10036027", "reactome": "R-BTA-77323", "name": "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77322", "species_113526" ], "products": [ "species_77320", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036040": { "compartment": "compartment_5460", "id": "reaction_10036040", "reactome": "R-BTA-77342", "name": "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77341", "species_113526" ], "products": [ "species_77339", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036042": { "compartment": "compartment_5460", "id": "reaction_10036042", "reactome": "R-BTA-77345", "name": "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77308", "species_113596" ], "products": [ "species_77343", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036012": { "compartment": "compartment_5460", "id": "reaction_10036012", "reactome": "R-BTA-77254", "name": "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77252" ], "products": [ "species_113529", "species_77253", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036021": { "compartment": "compartment_5460", "id": "reaction_10036021", "reactome": "R-BTA-77263", "name": "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77261" ], "products": [ "species_77255", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10036025": { "compartment": "compartment_5460", "id": "reaction_10036025", "reactome": "R-BTA-77312", "name": "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77251" ], "products": [ "species_73871", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036023": { "compartment": "compartment_5460", "id": "reaction_10036023", "reactome": "R-BTA-77274", "name": "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77272" ], "products": [ "species_77273", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10086403": { "compartment": "compartment_70616", "id": "reaction_10086403", "reactome": "R-BTA-8933547", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977314", "species_10086393" ], "products": [ "species_29374", "species_10086396" ], "modifiers": [ [ "species_10086400", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008382", "ENSBTAT00000008382", "ENSBTAT00000003130" ] }, "reaction_10036664": { "compartment": "compartment_5460", "id": "reaction_10036664", "reactome": "R-BTA-109998", "name": "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109994" ], "products": [ "species_77343" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036218": { "compartment": "compartment_5460", "id": "reaction_10036218", "reactome": "R-BTA-109338", "name": "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77358" ], "products": [ "species_77360" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036220": { "compartment": "compartment_5460", "id": "reaction_10036220", "reactome": "R-BTA-109341", "name": "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_109986" ], "products": [ "species_109990", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10075607": { "compartment": "compartment_70101", "id": "reaction_10075607", "reactome": "R-BTA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5690044" ], "products": [ "species_5690064", "species_76194" ], "modifiers": [ [ "species_10075600", "catalyst" ], [ "species_10075605", "catalyst" ] ], "additional_components": [ "CHEBI:61907", "CHEBI:33184", "CHEBI:59554", "species_30495", "F6QGE6", "ENSBTAT00000021731", "A6QQA9", "ENSBTAT00000074250", "A0A3Q1MI69", "ENSBTAT00000075163", "E1BNW7", "ENSBTAT00000014753", "ENSBTAT00000024898" ] }, "reaction_10076806": { "compartment": "compartment_5460", "id": "reaction_10076806", "reactome": "R-BTA-5695980", "name": "ACAD10 dehydrogenates S-2MPDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_5695946" ], "products": [ "species_5695949", "species_31649" ], "modifiers": [ [ "species_10076803", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080862" ] }, "reaction_10042860": { "compartment": "compartment_70101", "id": "reaction_10042860", "reactome": "R-BTA-200406", "name": "CPT1A,B transfers PALM to CAR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549207", "species_200993" ], "products": [ "species_201034", "species_76194" ], "modifiers": [ [ "species_10042857", "catalyst" ], [ "species_29508", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMV3", "ENSBTAT00000069870", "Q58DK1", "ENSBTAT00000021357" ] }, "reaction_10042897": { "compartment": "compartment_17927", "id": "reaction_10042897", "reactome": "R-BTA-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10042894", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000217" ] }, "reaction_10085185": { "compartment": "compartment_70101", "id": "reaction_10085185", "reactome": "R-BTA-8866941", "name": "MID1IP1 binds THRSP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085181", "species_10085177" ], "products": [ "species_10085183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015490", "ENSBTAT00000015231", "Q08E46", "ENSBTAT00000015231", "A0A3S5ZPK2", "ENSBTAT00000015490" ] }, "reaction_10077001": { "compartment": "compartment_12045", "id": "reaction_10077001", "reactome": "R-BTA-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192172", "species_5696426" ], "products": [ "species_5696412", "species_162743" ], "modifiers": [ [ "species_10076998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025081" ] }, "reaction_10044657": { "compartment": "compartment_876", "id": "reaction_10044657", "reactome": "R-BTA-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266013" ], "products": [ "species_266074", "species_210382" ], "modifiers": [ [ "species_10044654", "catalyst" ] ], "additional_components": [ "F1MYJ3", "ENSBTAT00000023658", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10064482": { "compartment": "compartment_12045", "id": "reaction_10064482", "reactome": "R-BTA-2161745", "name": "20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2161636" ], "products": [ "species_29356", "species_29366", "species_2142740" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064581": { "compartment": "compartment_70101", "id": "reaction_10064581", "reactome": "R-BTA-2162019", "name": "LTA4 is converted to EXA4 by ALOX15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281" ], "products": [ "species_2142772" ], "modifiers": [ [ "species_10064560", "catalyst" ] ], "additional_components": [ "P27479", "ENSBTAT00000015911", "species_71067" ] }, "reaction_10064503": { "compartment": "compartment_12045", "id": "reaction_10064503", "reactome": "R-BTA-2161792", "name": "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2142740" ], "products": [ "species_2161582", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064578": { "compartment": "compartment_70101", "id": "reaction_10064578", "reactome": "R-BTA-2162002", "name": "Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142718" ], "modifiers": [ [ "species_10064575", "catalyst" ] ], "additional_components": [ "F1MXW0", "ENSBTAT00000011570", "species_71067", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064546": { "compartment": "compartment_12045", "id": "reaction_10064546", "reactome": "R-BTA-2161951", "name": "Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142738" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064554": { "compartment": "compartment_70101", "id": "reaction_10064554", "reactome": "R-BTA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064565": { "compartment": "compartment_70101", "id": "reaction_10064565", "reactome": "R-BTA-2161964", "name": "Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142811" ], "modifiers": [ [ "species_10064562", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064567": { "compartment": "compartment_70101", "id": "reaction_10064567", "reactome": "R-BTA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064534": { "compartment": "compartment_70101", "id": "reaction_10064534", "reactome": "R-BTA-2161948", "name": "Arachidonic acid is converted to 12-oxoETE by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29768" ], "products": [ "species_2142745" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10076382": { "compartment": "compartment_12045", "id": "reaction_10076382", "reactome": "R-BTA-5693742", "name": "FAAH hydrolyses AEA to AA and ETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693754" ], "products": [ "species_1498751", "species_29768" ], "modifiers": [ [ "species_10076379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071864" ] }, "reaction_10064506": { "compartment": "compartment_70101", "id": "reaction_10064506", "reactome": "R-BTA-2161794", "name": "Arachidonic acid is converted to HXA3/B3 by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2162031" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:36190", "CHEBI:34784", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10086336": { "compartment": "compartment_984", "id": "reaction_10086336", "reactome": "R-BTA-8932633", "name": "PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8932801" ], "products": [ "species_8932804" ], "modifiers": [ [ "species_10086333", "catalyst" ] ], "additional_components": [ "Q1JQD3", "ENSBTAT00000049076", "species_74016", "Q2KIW1", "ENSBTAT00000020790" ] }, "reaction_10064521": { "compartment": "compartment_12045", "id": "reaction_10064521", "reactome": "R-BTA-2161890", "name": "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142739" ], "modifiers": [ [ "species_10064518", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10064526": { "compartment": "compartment_12045", "id": "reaction_10064526", "reactome": "R-BTA-2161899", "name": "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_2161753", "species_29366" ], "modifiers": [ [ "species_10064523", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "A0A3S5ZP79", "ENSBTAT00000027159", "F1MM10", "ENSBTAT00000061300", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10065210": { "compartment": "compartment_17957", "id": "reaction_10065210", "reactome": "R-BTA-2309773", "name": "PGG2 is reduced to PGH2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10065205", "catalyst" ], [ "species_549282", "catalyst" ], [ "species_10065208", "inhibitor" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064442": { "compartment": "compartment_70101", "id": "reaction_10064442", "reactome": "R-BTA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064474": { "compartment": "compartment_12045", "id": "reaction_10064474", "reactome": "R-BTA-2161660", "name": "PGH2 is isomerised to PGE2 by PTGES", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10064471", "catalyst" ] ], "additional_components": [ "species_29450", "Q95L14", "ENSBTAT00000025912" ] }, "reaction_10065213": { "compartment": "compartment_70101", "id": "reaction_10065213", "reactome": "R-BTA-2309779", "name": "PTGS2 dimer binds PTGS2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9716714", "species_10065205" ], "products": [ "species_10065208" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064445": { "compartment": "compartment_70101", "id": "reaction_10064445", "reactome": "R-BTA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064479": { "compartment": "compartment_70101", "id": "reaction_10064479", "reactome": "R-BTA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10064476", "catalyst" ] ], "additional_components": [ "species_29450", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10064465": { "compartment": "compartment_70101", "id": "reaction_10064465", "reactome": "R-BTA-2161651", "name": "PGE2 is converted to PGF2a by CBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265287" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10064462", "catalyst" ] ], "additional_components": [ "A0A3Q1NG39", "ENSBTAT00000084736", "Q3T0T9", "ENSBTAT00000043292" ] }, "reaction_10044599": { "compartment": "compartment_70101", "id": "reaction_10044599", "reactome": "R-BTA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10044596", "catalyst" ] ], "additional_components": [ "A0A3Q1LFK5", "ENSBTAT00000071669", "A0A452DIU3", "ENSBTAT00000023908" ] }, "reaction_10065225": { "compartment": "compartment_70101", "id": "reaction_10065225", "reactome": "R-BTA-2314686", "name": "Aspirin acetylates PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065205", "species_2314693" ], "products": [ "species_10064543", "species_2314690" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10065216": { "compartment": "compartment_17957", "id": "reaction_10065216", "reactome": "R-BTA-2309787", "name": "Arachidonic acid is oxidised to PGG2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064452": { "compartment": "compartment_12045", "id": "reaction_10064452", "reactome": "R-BTA-2161620", "name": "PGH2 is isomerised to PGD2 by PTGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30138" ], "products": [ "species_2161634" ], "modifiers": [ [ "species_10064449", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020065" ] }, "reaction_10065223": { "compartment": "compartment_70101", "id": "reaction_10065223", "reactome": "R-BTA-2314678", "name": "Aspirin acetylates PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037745", "species_2314693" ], "products": [ "species_10065221", "species_2314690" ], "modifiers": [], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355", "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10064511": { "compartment": "compartment_12045", "id": "reaction_10064511", "reactome": "R-BTA-2161795", "name": "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2161639" ], "modifiers": [ [ "species_10064508", "catalyst" ] ], "additional_components": [ "CHEBI:63995", "CHEBI:63994", "CHEBI:63579", "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064531": { "compartment": "compartment_12045", "id": "reaction_10064531", "reactome": "R-BTA-2161940", "name": "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142780" ], "modifiers": [ [ "species_10064528", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785", "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064516": { "compartment": "compartment_12045", "id": "reaction_10064516", "reactome": "R-BTA-2161814", "name": "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142836" ], "modifiers": [ [ "species_10064513", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1N3I8", "ENSBTAT00000021785", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10047033": { "compartment": "compartment_17951", "id": "reaction_10047033", "reactome": "R-BTA-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047030", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1LWZ7", "ENSBTAT00000082299", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10047056": { "compartment": "compartment_17951", "id": "reaction_10047056", "reactome": "R-BTA-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_353123" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10047042": { "compartment": "compartment_17951", "id": "reaction_10047042", "reactome": "R-BTA-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047039", "catalyst" ] ], "additional_components": [ "A4IFA4", "ENSBTAT00000044120", "species_113596" ] }, "reaction_10047044": { "compartment": "compartment_17951", "id": "reaction_10047044", "reactome": "R-BTA-389897", "name": "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389569" ], "products": [ "species_389893" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10077835": { "compartment": "compartment_17951", "id": "reaction_10077835", "reactome": "R-BTA-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_6787810" ], "products": [ "species_113575", "species_6787814" ], "modifiers": [ [ "species_10077832", "catalyst" ] ], "additional_components": [ "Q3ZBW2", "ENSBTAT00000000134" ] }, "reaction_10077784": { "compartment": "compartment_17951", "id": "reaction_10077784", "reactome": "R-BTA-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6786723", "species_113602" ], "products": [ "species_6786715", "species_389556" ], "modifiers": [ [ "species_10077781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072961" ] }, "reaction_10075576": { "compartment": "compartment_17951", "id": "reaction_10075576", "reactome": "R-BTA-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690520", "species_141343" ], "products": [ "species_5690539", "species_193514" ], "modifiers": [ [ "species_10075573", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "CHEBI:59554", "species_30495", "A0A3Q1N6L4", "ENSBTAT00000074004", "A0A3S5ZPS3", "ENSBTAT00000003683", "E1BBG0", "ENSBTAT00000013568" ] }, "reaction_10047053": { "compartment": "compartment_17951", "id": "reaction_10047053", "reactome": "R-BTA-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10082880": { "compartment": "compartment_17951", "id": "reaction_10082880", "reactome": "R-BTA-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10082877", "catalyst" ] ], "additional_components": [ "A0A3Q1LP28", "ENSBTAT00000083505" ] }, "reaction_10054592": { "compartment": "compartment_17951", "id": "reaction_10054592", "reactome": "R-BTA-977317", "name": "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977323" ], "products": [ "species_353123", "species_389536" ], "modifiers": [ [ "species_10054589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005562" ] }, "reaction_10047058": { "compartment": "compartment_17947", "id": "reaction_10047058", "reactome": "R-BTA-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10082889": { "compartment": "compartment_17947", "id": "reaction_10082889", "reactome": "R-BTA-6809810", "name": "PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6809811", "species_113602" ], "products": [ "species_389615", "species_389556" ], "modifiers": [ [ "species_10082886", "catalyst" ] ], "additional_components": [ "G3X6L7", "ENSBTAT00000008962" ] }, "reaction_10047001": { "compartment": "compartment_17951", "id": "reaction_10047001", "reactome": "R-BTA-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389615", "species_389537" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10046998", "catalyst" ] ], "additional_components": [ "species_71067", "O18778", "ENSBTAT00000010126" ] }, "reaction_10046984": { "compartment": "compartment_17951", "id": "reaction_10046984", "reactome": "R-BTA-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10046981", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10046989": { "compartment": "compartment_17951", "id": "reaction_10046989", "reactome": "R-BTA-389622", "name": "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389596", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389615", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10046992": { "compartment": "compartment_17951", "id": "reaction_10046992", "reactome": "R-BTA-389632", "name": "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6811612", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389569", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10083389": { "compartment": "compartment_12045", "id": "reaction_10083389", "reactome": "R-BTA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10083386", "catalyst" ] ], "additional_components": [ "Q2KIA4", "ENSBTAT00000025820" ] }, "reaction_10051261": { "compartment": "compartment_70101", "id": "reaction_10051261", "reactome": "R-BTA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10051258", "catalyst" ] ], "additional_components": [ "A6QNQ7", "ENSBTAT00000067475", "E1BBR7", "ENSBTAT00000020842" ] }, "reaction_10042961": { "compartment": "compartment_70101", "id": "reaction_10042961", "reactome": "R-BTA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10042958", "catalyst" ] ], "additional_components": [ "Q1LZF6", "ENSBTAT00000064114", "A0A3Q1LPX2", "ENSBTAT00000080693", "A0A3Q1LWT4", "ENSBTAT00000078831", "F1MEX9", "ENSBTAT00000022939" ] }, "reaction_10074353": { "compartment": "compartment_12045", "id": "reaction_10074353", "reactome": "R-BTA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10074350", "catalyst" ] ], "additional_components": [ "F1MXJ1", "ENSBTAT00000046976" ] }, "reaction_10051252": { "compartment": "compartment_70101", "id": "reaction_10051252", "reactome": "R-BTA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10044985": { "compartment": "compartment_876", "id": "reaction_10044985", "reactome": "R-BTA-352174", "name": "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352186", "species_70106", "species_74113" ], "products": [ "species_351626", "species_352169", "species_83910" ], "modifiers": [ [ "species_10044982", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_29612", "species_29642", "species_29472", "species_352036", "species_29642", "species_29612", "ENSBTAT00000011214" ] }, "reaction_10044955": { "compartment": "compartment_876", "id": "reaction_10044955", "reactome": "R-BTA-352103", "name": "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044952", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000072259" ] }, "reaction_10045501": { "compartment": "compartment_876", "id": "reaction_10045501", "reactome": "R-BTA-375776", "name": "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045498", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000019060" ] }, "reaction_10044978": { "compartment": "compartment_876", "id": "reaction_10044978", "reactome": "R-BTA-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10044975", "catalyst" ] ], "additional_components": [ "species_352006", "species_352030", "species_351993", "species_352030", "species_352006", "species_351993", "ENSBTAT00000012176" ] }, "reaction_10044948": { "compartment": "compartment_876", "id": "reaction_10044948", "reactome": "R-BTA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10044945", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "CHEBI:58045", "species_379717", "species_351990", "species_111707", "species_379732", "species_29642", "CHEBI:57427", "species_174390", "CHEBI:18240", "species_29702", "species_29472", "species_379717", "species_351990", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:18240", "CHEBI:58045", "species_29702", "species_352036", "species_29642", "species_111707", "ENSBTAT00000076418" ] }, "reaction_10045494": { "compartment": "compartment_876", "id": "reaction_10045494", "reactome": "R-BTA-375770", "name": "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045491", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000009736" ] }, "reaction_10088905": { "compartment": "compartment_70101", "id": "reaction_10088905", "reactome": "R-BTA-8959781", "name": "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959777" ], "products": [ "species_8959775" ], "modifiers": [ [ "species_10088902", "catalyst" ] ], "additional_components": [ "CHEBI:28229", "species_113586", "species_113530", "species_29612", "CHEBI:32551", "CHEBI:27747", "species_113586", "CHEBI:32551", "species_113530", "species_29612", "CHEBI:28229", "CHEBI:27747", "ENSBTAT00000018163" ] }, "reaction_10085384": { "compartment": "compartment_876", "id": "reaction_10085384", "reactome": "R-BTA-8870354", "name": "SLC36A4 transports extracellular L-Pro to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033" ], "products": [ "species_113538" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10045480": { "compartment": "compartment_876", "id": "reaction_10045480", "reactome": "R-BTA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10045477", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "species_29472", "CHEBI:58045", "species_111707", "species_379732", "species_29424", "CHEBI:57427", "species_174390", "species_352030", "species_351993", "species_29702", "species_29424", "species_29472", "species_352030", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_352036", "species_111707", "species_352006", "species_351993", "ENSBTAT00000064818" ] }, "reaction_10044971": { "compartment": "compartment_876", "id": "reaction_10044971", "reactome": "R-BTA-352136", "name": "SLC38A4 (ATA3)-mediated uptake of arginine and lysine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352128" ], "products": [ "species_352135" ], "modifiers": [ [ "species_10044968", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000070473" ] }, "reaction_10044941": { "compartment": "compartment_876", "id": "reaction_10044941", "reactome": "R-BTA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10044938", "catalyst" ] ], "additional_components": [ "species_73590", "species_428571", "species_352015", "CHEBI:48950", "CHEBI:48950", "species_73590", "species_352015", "species_428571", "ENSBTAT00000067153" ] }, "reaction_10045487": { "compartment": "compartment_876", "id": "reaction_10045487", "reactome": "R-BTA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10045484", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "CHEBI:58045", "species_29612", "species_379732", "species_29424", "species_113530", "species_73590", "CHEBI:32551", "species_111707", "CHEBI:57427", "species_174390", "species_29702", "species_379732", "species_29702", "species_29612", "CHEBI:32551", "species_29424", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_73590", "species_352036", "species_111707", "species_113530", "species_352006", "ENSBTAT00000083685" ] }, "reaction_10045473": { "compartment": "compartment_876", "id": "reaction_10045473", "reactome": "R-BTA-375405", "name": "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_375409" ], "products": [ "species_70106", "species_375414" ], "modifiers": [ [ "species_10045470", "catalyst" ] ], "additional_components": [ "species_379717", "species_29424", "species_29424", "species_379717", "ENSBTAT00000027731" ] }, "reaction_10044962": { "compartment": "compartment_876", "id": "reaction_10044962", "reactome": "R-BTA-352107", "name": "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044959", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000015260" ] }, "reaction_10044964": { "compartment": "compartment_876", "id": "reaction_10044964", "reactome": "R-BTA-352108", "name": "SLC38A2 (ATA2)-mediated uptake of neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352091", "species_74113" ], "products": [ "species_352088", "species_83910" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_379717", "species_351990", "species_379732", "species_29642", "species_29424", "CHEBI:57427", "species_174390", "species_29472", "species_29424", "species_379717", "species_379732", "species_351990", "CHEBI:57427", "species_174390", "species_352036", "species_29642", "ENSBTAT00000014749" ] }, "reaction_10044934": { "compartment": "compartment_876", "id": "reaction_10044934", "reactome": "R-BTA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10044931", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016676" ] }, "reaction_10039272": { "compartment": "compartment_984", "id": "reaction_10039272", "reactome": "R-BTA-166542", "name": "beta-NGF dimer binds to TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039264", "species_10039258" ], "products": [ "species_10039266" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10040684": { "compartment": "compartment_876", "id": "reaction_10040684", "reactome": "R-BTA-190065", "name": "Activated TrkA receptor internalizes to endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039569" ], "products": [ "species_10039684" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039270": { "compartment": "compartment_876", "id": "reaction_10039270", "reactome": "R-BTA-166538", "name": "The bound receptor dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039266", "species_10039258" ], "products": [ "species_10039268" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10088473": { "compartment": "compartment_17957", "id": "reaction_10088473", "reactome": "R-BTA-8952289", "name": "FAM20C phosphorylates FAM20C substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088246", "species_8931885" ], "products": [ "species_10088464", "species_8931884" ], "modifiers": [ [ "species_10088246", "catalyst" ], [ "species_10088471", "catalyst" ] ], "additional_components": [ "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MI67", "ENSBTAT00000025557", "A0A3Q1NJR8", "ENSBTAT00000071014", "Q2KJH1", "ENSBTAT00000004992", "A0A5H1ZRH6", "ENSBTAT00000028238", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3X6N3", "ENSBTAT00000009564", "E1B8P3", "ENSBTAT00000002384", "P11116", "ENSBTAT00000020080", "F1MD77", "ENSBTAT00000015881", "P81644", "ENSBTAT00000012138", "A0A3Q1LEU1", "ENSBTAT00000081148", "E1BDK6", "ENSBTAT00000057452", "E1BG25", "ENSBTAT00000046533", "F1MD94", "ENSBTAT00000027836", "A4FUZ9", "ENSBTAT00000026336", "A0A452DII7", "ENSBTAT00000016252", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1MS36", "ENSBTAT00000076629", "Q95M18", "ENSBTAT00000004364", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "A0A3Q1MY30", "ENSBTAT00000082437", "E1BJF8", "ENSBTAT00000022706", "P02817", "ENSBTAT00000016034", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A140T8C8", "ENSBTAT00000053071", "P12763", "ENSBTAT00000000673", "F1MEA1", "ENSBTAT00000024433", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "F1MY12", "ENSBTAT00000016092", "F6RJ01", "ENSBTAT00000027753", "A0A3Q1LRR3", "ENSBTAT00000074422", "G3N348", "ENSBTAT00000082028", "P01035", "ENSBTAT00000000790", "A0A3Q1LMK4", "ENSBTAT00000076179", "A0A452DJ03", "ENSBTAT00000028372", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "E1BLA8", "ENSBTAT00000044756", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LIS3", "ENSBTAT00000085388", "Q27967", "ENSBTAT00000002631", "A0A3Q1N9Y5", "ENSBTAT00000085713", "G3X724", "ENSBTAT00000065790", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QPR4", "ENSBTAT00000044682", "A6QQR3", "ENSBTAT00000044682", "A0A3Q1MEX5", "ENSBTAT00000072231", "A0A3Q1NAS1", "ENSBTAT00000074235", "E1BHJ7", "ENSBTAT00000016190", "F6QSG5", "ENSBTAT00000056456", "A0A3Q1NIX0", "ENSBTAT00000078756", "A6QP86", "ENSBTAT00000054074", "G3N2W6", "ENSBTAT00000065790", "G3N2L2", "ENSBTAT00000063521", "Q6PX77", "ENSBTAT00000064918", "P34955", "ENSBTAT00000072441", "P01211", "ENSBTAT00000087134", "Q1LZE9", "ENSBTAT00000020194", "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MJW4", "ENSBTAT00000001439" ] }, "reaction_10046621": { "compartment": "compartment_984", "id": "reaction_10046621", "reactome": "R-BTA-381487", "name": "IGFBP1 binds IGF forming IGF:IGFBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046613", "species_10046617" ], "products": [ "species_10046619" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014713", "ENSBTAT00000064194", "P24591", "ENSBTAT00000064194", "P07455", "ENSBTAT00000014713" ] }, "reaction_10068959": { "compartment": "compartment_7660", "id": "reaction_10068959", "reactome": "R-BTA-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068951", "species_10068947", "species_10068943", "species_10068955" ], "products": [ "species_10068957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064363", "ENSBTAT00000074434", "ENSBTAT00000002664", "ENSBTAT00000018360", "G3X746", "ENSBTAT00000018360", "Q2KIG1", "ENSBTAT00000002664", "A0A3Q1NMK6", "ENSBTAT00000074434", "G3N0Y4", "ENSBTAT00000064363" ] }, "reaction_10061480": { "compartment": "compartment_876", "id": "reaction_10061480", "reactome": "R-BTA-1963582", "name": "Trans-autophosphorylation of ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10057121" ], "modifiers": [ [ "species_10061477", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10061469": { "compartment": "compartment_876", "id": "reaction_10061469", "reactome": "R-BTA-1963581", "name": "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10061466" ], "products": [ "species_29370", "species_10057130" ], "modifiers": [ [ "species_10061466", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10057692": { "compartment": "compartment_70101", "id": "reaction_10057692", "reactome": "R-BTA-1306969", "name": "GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10057688" ], "products": [ "species_10057690" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10057695": { "compartment": "compartment_876", "id": "reaction_10057695", "reactome": "R-BTA-1306972", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057690", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10086415": { "compartment": "compartment_70101", "id": "reaction_10086415", "reactome": "R-BTA-8934465", "name": "SHC1 binds PTPN12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084846", "species_10086408" ], "products": [ "species_10086413" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068950", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1M0B4", "ENSBTAT00000068950" ] }, "reaction_10057139": { "compartment": "compartment_876", "id": "reaction_10057139", "reactome": "R-BTA-1250195", "name": "SHC1 phosphorylation by ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057134" ], "products": [ "species_29370", "species_10057136" ], "modifiers": [ [ "species_10057134", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10083483": { "compartment": "compartment_70101", "id": "reaction_10083483", "reactome": "R-BTA-8848005", "name": "ERBB2 promotes PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083475", "species_113592" ], "products": [ "species_29370", "species_10057132", "species_10083480" ], "modifiers": [ [ "species_10083475", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083477": { "compartment": "compartment_876", "id": "reaction_10083477", "reactome": "R-BTA-8847995", "name": "Activated ERBB2 binds PTK6 (BRK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083473", "species_10057132" ], "products": [ "species_10083475" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10057700": { "compartment": "compartment_876", "id": "reaction_10057700", "reactome": "R-BTA-1306979", "name": "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057697", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077601": { "compartment": "compartment_70101", "id": "reaction_10077601", "reactome": "R-BTA-6785636", "name": "Phosphorylated ERBB2 heterodimers bind MEMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057132", "species_10077597" ], "products": [ "species_10077599" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000085928", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077605": { "compartment": "compartment_70101", "id": "reaction_10077605", "reactome": "R-BTA-6785648", "name": "MEMO1 binds RHOA:GTP:DIAPH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073537", "species_10077599" ], "products": [ "species_10077603" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10084849": { "compartment": "compartment_876", "id": "reaction_10084849", "reactome": "R-BTA-8863804", "name": "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10057132" ], "products": [ "species_29372", "species_10084842" ], "modifiers": [ [ "species_10084846", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000068950" ] }, "reaction_10061458": { "compartment": "compartment_876", "id": "reaction_10061458", "reactome": "R-BTA-1963563", "name": "MATK (CSK homologous kinase) binds phosphorylated ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061454", "species_10057132" ], "products": [ "species_10061456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069379", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q58D16", "ENSBTAT00000069379" ] }, "reaction_10057740": { "compartment": "compartment_70101", "id": "reaction_10057740", "reactome": "R-BTA-1358795", "name": "Deubiquitination of RNF41 by P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057737" ], "products": [ "species_10033408", "species_10055232", "species_10057726" ], "modifiers": [ [ "species_10057737", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057742": { "compartment": "compartment_70101", "id": "reaction_10057742", "reactome": "R-BTA-1358797", "name": "Ubiquitinated RNF41 binds P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057726", "species_10057709" ], "products": [ "species_10057737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057744": { "compartment": "compartment_70101", "id": "reaction_10057744", "reactome": "R-BTA-1358801", "name": "ERBB3 binds RNF41 ubiquitin ligase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055232", "species_10057066" ], "products": [ "species_10057714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087037", "ENSBTAT00000013790", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057712": { "compartment": "compartment_70101", "id": "reaction_10057712", "reactome": "R-BTA-1358789", "name": "Self-ubiquitination of RNF41", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10055232" ], "products": [ "species_10057709" ], "modifiers": [ [ "species_10055232", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037" ] }, "reaction_10057719": { "compartment": "compartment_70101", "id": "reaction_10057719", "reactome": "R-BTA-1358790", "name": "RNF41 ubiquitinates ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057714", "species_10033408" ], "products": [ "species_10057716", "species_10055232" ], "modifiers": [ [ "species_10057714", "catalyst" ] ], "additional_components": [ "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QR62", "ENSBTAT00000013790", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057735": { "compartment": "compartment_70101", "id": "reaction_10057735", "reactome": "R-BTA-1358792", "name": "RNF41 ubiquitinates activated ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057730", "species_10033408" ], "products": [ "species_10057732", "species_10055232" ], "modifiers": [ [ "species_10057730", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10061492": { "compartment": "compartment_876", "id": "reaction_10061492", "reactome": "R-BTA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10061466" ], "modifiers": [ [ "species_10061489", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10066602": { "compartment": "compartment_70101", "id": "reaction_10066602", "reactome": "R-BTA-3165230", "name": "SLC52A1,2,3 transport RIB from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3165253" ], "products": [ "species_196931" ], "modifiers": [ [ "species_10066599", "catalyst" ], [ "species_73524", "inhibitor" ], [ "species_29386", "inhibitor" ] ], "additional_components": [ "A0A3Q1N6I5", "ENSBTAT00000083852", "Q5E9R1", "ENSBTAT00000084768" ] }, "reaction_10041772": { "compartment": "compartment_70101", "id": "reaction_10041772", "reactome": "R-BTA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10041769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081315" ] }, "reaction_10041790": { "compartment": "compartment_70101", "id": "reaction_10041790", "reactome": "R-BTA-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29386" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10041787", "catalyst" ] ], "additional_components": [ "F1MNS5", "ENSBTAT00000061365" ] }, "reaction_10041781": { "compartment": "compartment_70101", "id": "reaction_10041781", "reactome": "R-BTA-196950", "name": "2xTRAP hydrolyzes FMN to RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73524" ], "products": [ "species_29372", "species_196931" ], "modifiers": [ [ "species_10041778", "catalyst" ] ], "additional_components": [ "E1B8A0", "ENSBTAT00000006339" ] }, "reaction_10041799": { "compartment": "compartment_70101", "id": "reaction_10041799", "reactome": "R-BTA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10041796", "catalyst" ] ], "additional_components": [ "species_29926", "F6R223", "ENSBTAT00000025762" ] }, "reaction_10056185": { "compartment": "compartment_876", "id": "reaction_10056185", "reactome": "R-BTA-1112602", "name": "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056174" ], "products": [ "species_10056180", "species_29370" ], "modifiers": [ [ "species_10056174", "catalyst" ], [ "species_10056183", "inhibitor" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056123": { "compartment": "compartment_876", "id": "reaction_10056123", "reactome": "R-BTA-1067659", "name": "Assembly of hexameric IL-6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056119" ], "products": [ "species_10056121" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056188": { "compartment": "compartment_876", "id": "reaction_10056188", "reactome": "R-BTA-1112604", "name": "Phosphorylated STATs are released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180" ], "products": [ "species_10056166", "species_10051764" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342" ] }, "reaction_10056127": { "compartment": "compartment_876", "id": "reaction_10056127", "reactome": "R-BTA-1067667", "name": "IL6 binds IL6R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_10056094" ], "products": [ "species_10056115" ], "modifiers": [ [ "species_10056125", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056176": { "compartment": "compartment_876", "id": "reaction_10056176", "reactome": "R-BTA-1112565", "name": "Tyrosine phosphorylated IL6ST binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10046556" ], "products": [ "species_10056174" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056178": { "compartment": "compartment_70101", "id": "reaction_10056178", "reactome": "R-BTA-1112587", "name": "STAT1 and STAT3 dimers translocate to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056201": { "compartment": "compartment_876", "id": "reaction_10056201", "reactome": "R-BTA-1112708", "name": "PTPN11 binds p-Y759-IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10040231" ], "products": [ "species_10056190" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056168": { "compartment": "compartment_876", "id": "reaction_10056168", "reactome": "R-BTA-1112510", "name": "IL6ST is tyrosine phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056149", "species_113592" ], "products": [ "species_10056166", "species_29370" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056170": { "compartment": "compartment_876", "id": "reaction_10056170", "reactome": "R-BTA-1112514", "name": "JAK activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056121" ], "products": [ "species_10056149", "species_29370" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056205": { "compartment": "compartment_876", "id": "reaction_10056205", "reactome": "R-BTA-1112727", "name": "Serine phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180", "species_113592" ], "products": [ "species_29370", "species_10056203" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056172": { "compartment": "compartment_70101", "id": "reaction_10056172", "reactome": "R-BTA-1112538", "name": "Phosphorylated STAT1, STAT3 form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051764" ], "products": [ "species_10051766" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056207": { "compartment": "compartment_876", "id": "reaction_10056207", "reactome": "R-BTA-1112755", "name": "SOCS3 binds IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10051731" ], "products": [ "species_10056183" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000011106", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056110": { "compartment": "compartment_984", "id": "reaction_10056110", "reactome": "R-BTA-1067651", "name": "IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056100" ], "products": [ "species_10056104" ], "modifiers": [ [ "species_10056108", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10091747": { "compartment": "compartment_984", "id": "reaction_10091747", "reactome": "R-BTA-9681294", "name": "IL6R binds IL6R inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_9715042" ], "products": [ "species_10056125" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056130": { "compartment": "compartment_984", "id": "reaction_10056130", "reactome": "R-BTA-1067676", "name": "IL6:IL6R-2 binds IL6ST-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056100", "species_10056106" ], "products": [ "species_10056108" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056194": { "compartment": "compartment_876", "id": "reaction_10056194", "reactome": "R-BTA-1112690", "name": "PTPN11 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10056190" ], "products": [ "species_10056192" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10056132": { "compartment": "compartment_876", "id": "reaction_10056132", "reactome": "R-BTA-1067688", "name": "IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056115" ], "products": [ "species_10056117" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056199": { "compartment": "compartment_876", "id": "reaction_10056199", "reactome": "R-BTA-1112703", "name": "PTPN11 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056190" ], "products": [ "species_10056196", "species_29370" ], "modifiers": [ [ "species_10056190", "catalyst" ] ], "additional_components": [ "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056102": { "compartment": "compartment_984", "id": "reaction_10056102", "reactome": "R-BTA-1067640", "name": "IL6 binds IL6R-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056098", "species_10056094" ], "products": [ "species_10056100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10087338": { "compartment": "compartment_984", "id": "reaction_10087338", "reactome": "R-BTA-8940998", "name": "IL36RN, IL1F10 bind IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087334", "species_10083514" ], "products": [ "species_10087336" ], "modifiers": [], "additional_components": [ "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10083522": { "compartment": "compartment_984", "id": "reaction_10083522", "reactome": "R-BTA-8848316", "name": "IL36 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083510", "species_10083514" ], "products": [ "species_10083516" ], "modifiers": [ [ "species_10083520", "inhibitor" ] ], "additional_components": [ "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000023970" ] }, "reaction_10050024": { "compartment": "compartment_70101", "id": "reaction_10050024", "reactome": "R-BTA-448678", "name": "CTSG cleaves CASP1(1-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050013" ], "products": [ "species_10050007", "species_10050005", "species_10050017", "species_10050015" ], "modifiers": [ [ "species_10050021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000054741" ] }, "reaction_10050011": { "compartment": "compartment_70101", "id": "reaction_10050011", "reactome": "R-BTA-448673", "name": "Formation of caspase-1 p10/p20 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050007", "species_10050005" ], "products": [ "species_10050009" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10050028": { "compartment": "compartment_70101", "id": "reaction_10050028", "reactome": "R-BTA-448702", "name": "Caspase-1 active tetramer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050009" ], "products": [ "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089595": { "compartment": "compartment_984", "id": "reaction_10089595", "reactome": "R-BTA-9007901", "name": "IL1F10 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332", "species_10083514" ], "products": [ "species_10089593" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10089597": { "compartment": "compartment_984", "id": "reaction_10089597", "reactome": "R-BTA-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037699", "species_113592" ], "products": [ "species_29370", "species_10039514" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10089591": { "compartment": "compartment_984", "id": "reaction_10089591", "reactome": "R-BTA-9007882", "name": "IL1F10 is cleaved", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332" ], "products": [ "species_10089589", "species_10089587" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000023975", "ENSBTAT00000023975" ] }, "reaction_10089625": { "compartment": "compartment_70101", "id": "reaction_10089625", "reactome": "R-BTA-9008696", "name": "IL37(?-218) translocates from the cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089617" ], "products": [ "species_10089623" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089819": { "compartment": "compartment_70101", "id": "reaction_10089819", "reactome": "R-BTA-9012556", "name": "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089810" ], "products": [ "species_10089816" ], "modifiers": [ [ "species_10089810", "catalyst" ] ], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10089615": { "compartment": "compartment_70101", "id": "reaction_10089615", "reactome": "R-BTA-9008684", "name": "TBK1 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_113592" ], "products": [ "species_29370", "species_10089613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000023134" ] }, "reaction_10083537": { "compartment": "compartment_984", "id": "reaction_10083537", "reactome": "R-BTA-8848335", "name": "IL37 binds IL18R1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083527", "species_10083531" ], "products": [ "species_10083535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001371", "ENSBTAT00000029311", "E1BLE5", "ENSBTAT00000029311", "F1MJ29", "ENSBTAT00000001371" ] }, "reaction_10089843": { "compartment": "compartment_70101", "id": "reaction_10089843", "reactome": "R-BTA-9012689", "name": "IL37(1-?) and IL37 (?-) dissocates from IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089816" ], "products": [ "species_10089814", "species_10089617", "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "ENSBTAT00000029311", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089621": { "compartment": "compartment_70101", "id": "reaction_10089621", "reactome": "R-BTA-9008694", "name": "IL37, IL37(?-218) translocates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619" ], "products": [ "species_10083531" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089812": { "compartment": "compartment_70101", "id": "reaction_10089812", "reactome": "R-BTA-9012542", "name": "IL37 binds 2x(CASP1(120-197):CASP1(317-404))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619", "species_10050026" ], "products": [ "species_10089810" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10049721": { "compartment": "compartment_876", "id": "reaction_10049721", "reactome": "R-BTA-445757", "name": "IL1 receptor antagonist protein binds Interleukin 1 receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049717", "species_10049713" ], "products": [ "species_10049719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087066", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "A0A3Q1MKE9", "ENSBTAT00000087066" ] }, "reaction_10043867": { "compartment": "compartment_70101", "id": "reaction_10043867", "reactome": "R-BTA-209087", "name": "IKBA is phosphorylated by Phospho IKKB kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043854" ], "products": [ "species_10043858", "species_29370" ], "modifiers": [ [ "species_10043864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022183", "ENSBTAT00000022183", "ENSBTAT00000009995" ] }, "reaction_10091757": { "compartment": "compartment_984", "id": "reaction_10091757", "reactome": "R-BTA-9681763", "name": "IL1R1 binds IL1R1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9681804", "species_10049707" ], "products": [ "species_10091755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006938", "F1ML75", "ENSBTAT00000006938" ] }, "reaction_10050428": { "compartment": "compartment_70101", "id": "reaction_10050428", "reactome": "R-BTA-450827", "name": "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050418", "species_113592" ], "products": [ "species_29370", "species_10050425" ], "modifiers": [ [ "species_10050418", "catalyst" ] ], "additional_components": [ "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10050420": { "compartment": "compartment_70101", "id": "reaction_10050420", "reactome": "R-BTA-450690", "name": "hp-IRAK1,hp-IRAK4 bind Pellino1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050416", "species_10050412" ], "products": [ "species_10050418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067567", "ENSBTAT00000028115", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10051095": { "compartment": "compartment_70101", "id": "reaction_10051095", "reactome": "R-BTA-507719", "name": "p62:MEKK3 binds to TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051091", "species_10039473" ], "products": [ "species_10051093" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015" ] }, "reaction_10085017": { "compartment": "compartment_7660", "id": "reaction_10085017", "reactome": "R-BTA-8865613", "name": "BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084951", "species_10085013" ], "products": [ "species_10085015" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018087", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTQ0", "ENSBTAT00000018087" ] }, "reaction_10091731": { "compartment": "compartment_70101", "id": "reaction_10091731", "reactome": "R-BTA-9679028", "name": "JAK3 binds JAK3 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_9678772" ], "products": [ "species_10091729" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10089251": { "compartment": "compartment_876", "id": "reaction_10089251", "reactome": "R-BTA-8983059", "name": "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089244" ], "products": [ "species_29370", "species_10089248" ], "modifiers": [ [ "species_10089244", "catalyst" ] ], "additional_components": [ "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10089253": { "compartment": "compartment_984", "id": "reaction_10089253", "reactome": "R-BTA-8983061", "name": "TSLP binds CRLF2:IL7R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089234", "species_10089240" ], "products": [ "species_10089242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10087787": { "compartment": "compartment_70101", "id": "reaction_10087787", "reactome": "R-BTA-8950731", "name": "CRLF1:IL27 translocates to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087772" ], "products": [ "species_10087785" ], "modifiers": [], "additional_components": [ "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10049946": { "compartment": "compartment_984", "id": "reaction_10049946", "reactome": "R-BTA-448421", "name": "Interleukin-27 translocates from the ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049938" ], "products": [ "species_10049944" ], "modifiers": [], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046" ] }, "reaction_10087726": { "compartment": "compartment_876", "id": "reaction_10087726", "reactome": "R-BTA-8950340", "name": "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087711" ], "products": [ "species_29370", "species_10087723" ], "modifiers": [ [ "species_10087711", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087774": { "compartment": "compartment_70101", "id": "reaction_10087774", "reactome": "R-BTA-8950504", "name": "IL27 binds CRLF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087770", "species_10087768" ], "products": [ "species_10087772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083936", "ENSBTAT00000074594", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10087793": { "compartment": "compartment_876", "id": "reaction_10087793", "reactome": "R-BTA-8950766", "name": "IL27RA dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049962" ], "products": [ "species_10087791" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022524", "A5D7S4", "ENSBTAT00000022524" ] }, "reaction_10049970": { "compartment": "compartment_984", "id": "reaction_10049970", "reactome": "R-BTA-448427", "name": "Interleukin-27 binds Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10049964", "species_10049944" ], "products": [ "species_10049966" ], "modifiers": [ [ "species_10049968", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "ENSBTAT00000022524" ] }, "reaction_10087671": { "compartment": "compartment_984", "id": "reaction_10087671", "reactome": "R-BTA-8950210", "name": "Interleukin-27 dissociates from Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049966" ], "products": [ "species_10049958", "species_10049964", "species_10049944" ], "modifiers": [ [ "species_10049940", "inhibitor" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "ENSBTAT00000083936" ] }, "reaction_10087783": { "compartment": "compartment_876", "id": "reaction_10087783", "reactome": "R-BTA-8950537", "name": "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049966" ], "products": [ "species_29370", "species_10087711" ], "modifiers": [ [ "species_10049966", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10087766": { "compartment": "compartment_70101", "id": "reaction_10087766", "reactome": "R-BTA-8950485", "name": "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087736" ], "products": [ "species_10087734", "species_29370" ], "modifiers": [ [ "species_10087736", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089321": { "compartment": "compartment_876", "id": "reaction_10089321", "reactome": "R-BTA-8983834", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089313" ], "products": [ "species_10089319", "species_29370" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089329": { "compartment": "compartment_876", "id": "reaction_10089329", "reactome": "R-BTA-8983835", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089325" ], "products": [ "species_29370", "species_10089327" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089331": { "compartment": "compartment_876", "id": "reaction_10089331", "reactome": "R-BTA-8983841", "name": "STAT1 associates with IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046556", "species_10089323" ], "products": [ "species_10089325" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10087763": { "compartment": "compartment_70101", "id": "reaction_10087763", "reactome": "R-BTA-8950453", "name": "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087752" ], "products": [ "species_29370", "species_10087760" ], "modifiers": [ [ "species_10087752", "catalyst" ] ], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089333": { "compartment": "compartment_876", "id": "reaction_10089333", "reactome": "R-BTA-8983845", "name": "p-STAT1 dissociates from IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089327" ], "products": [ "species_10087758", "species_10089323" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087780": { "compartment": "compartment_70101", "id": "reaction_10087780", "reactome": "R-BTA-8950522", "name": "p-STAT1:p-STAT4 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087776" ], "products": [ "species_10087778" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10049928": { "compartment": "compartment_984", "id": "reaction_10049928", "reactome": "R-BTA-447130", "name": "Interleukin-23 binds interleukin-23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049924", "species_10049904", "species_10049914" ], "products": [ "species_10049926" ], "modifiers": [], "additional_components": [ "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10087789": { "compartment": "compartment_984", "id": "reaction_10087789", "reactome": "R-BTA-8950741", "name": "IL12B:IL23A translocates from ER lumen to extracellular space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087669" ], "products": [ "species_10049904" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MSN4", "ENSBTAT00000005745", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10087697": { "compartment": "compartment_70101", "id": "reaction_10087697", "reactome": "R-BTA-8950269", "name": "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087690" ], "products": [ "species_29370", "species_10087694" ], "modifiers": [ [ "species_10087690", "catalyst" ] ], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10088498": { "compartment": "compartment_70101", "id": "reaction_10088498", "reactome": "R-BTA-8952749", "name": "STAT4 binds p-Y-IL23R in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087674", "species_10087688" ], "products": [ "species_10087690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10051194": { "compartment": "compartment_70101", "id": "reaction_10051194", "reactome": "R-BTA-508451", "name": "PTK2B is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051187" ], "products": [ "species_10051192" ], "modifiers": [], "additional_components": [ "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857", "A0A3Q1LVP1", "ENSBTAT00000084967" ] }, "reaction_10051196": { "compartment": "compartment_70101", "id": "reaction_10051196", "reactome": "R-BTA-508513", "name": "PTK2B binds JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_10047260" ], "products": [ "species_10051187" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "ENSBTAT00000084967", "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10050527": { "compartment": "compartment_70101", "id": "reaction_10050527", "reactome": "R-BTA-451900", "name": "IL2RB binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050134", "species_10049950" ], "products": [ "species_10050136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074166", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166" ] }, "reaction_10089736": { "compartment": "compartment_70101", "id": "reaction_10089736", "reactome": "R-BTA-9011748", "name": "IL9R binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089732", "species_10049950" ], "products": [ "species_10089734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009944", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MTF9", "ENSBTAT00000009944" ] }, "reaction_10089363": { "compartment": "compartment_70101", "id": "reaction_10089363", "reactome": "R-BTA-8985943", "name": "p-Y701-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089359" ], "products": [ "species_10089361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10050619": { "compartment": "compartment_876", "id": "reaction_10050619", "reactome": "R-BTA-453104", "name": "Phosphorylated SHC1 recruits GRB2:GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050571", "species_10050569" ], "products": [ "species_10050617" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10050623": { "compartment": "compartment_70101", "id": "reaction_10050623", "reactome": "R-BTA-453111", "name": "Phosphorylated SHC recruits GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10050569" ], "products": [ "species_10050621" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10052254": { "compartment": "compartment_876", "id": "reaction_10052254", "reactome": "R-BTA-912527", "name": "SHC1 mediates cytokine-induced phosphorylation of GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050617" ], "products": [ "species_29370", "species_10052252" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10052337": { "compartment": "compartment_70101", "id": "reaction_10052337", "reactome": "R-BTA-913374", "name": "Phosphorylated SHC1 recruits SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052333", "species_10050569" ], "products": [ "species_10052335" ], "modifiers": [], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10052343": { "compartment": "compartment_70101", "id": "reaction_10052343", "reactome": "R-BTA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052339", "species_10035485" ], "products": [ "species_10052341" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529" ] }, "reaction_10089291": { "compartment": "compartment_17940", "id": "reaction_10089291", "reactome": "R-BTA-8983335", "name": "IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255" ], "products": [ "species_10089289" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089311": { "compartment": "compartment_70101", "id": "reaction_10089311", "reactome": "R-BTA-8983384", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089307", "species_10089305" ], "products": [ "species_10089309" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089267": { "compartment": "compartment_70101", "id": "reaction_10089267", "reactome": "R-BTA-8983300", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255", "species_113592" ], "products": [ "species_29370", "species_10089264" ], "modifiers": [ [ "species_10089255", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089269": { "compartment": "compartment_984", "id": "reaction_10089269", "reactome": "R-BTA-8983307", "name": "IL15 binds IL15RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050128", "species_10050124" ], "products": [ "species_10050130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083836", "ENSBTAT00000084366", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089689": { "compartment": "compartment_984", "id": "reaction_10089689", "reactome": "R-BTA-9009485", "name": "IL34:CSF1 binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089685", "species_10077839" ], "products": [ "species_10089687" ], "modifiers": [], "additional_components": [ "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179", "ENSBTAT00000016977", "A7Z067", "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10089691": { "compartment": "compartment_984", "id": "reaction_10089691", "reactome": "R-BTA-9009488", "name": "IL34 binds CSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089683", "species_10049979" ], "products": [ "species_10089685" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076179", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10090027": { "compartment": "compartment_984", "id": "reaction_10090027", "reactome": "R-BTA-9014052", "name": "TXLNA (IL14) binds syntaxin3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090023", "species_10050140" ], "products": [ "species_10090025" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069233", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A3Q1LYB4", "ENSBTAT00000069233" ] }, "reaction_10049983": { "compartment": "compartment_984", "id": "reaction_10049983", "reactome": "R-BTA-448632", "name": "IL34 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049979" ], "products": [ "species_10049981" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664" ] }, "reaction_10090031": { "compartment": "compartment_984", "id": "reaction_10090031", "reactome": "R-BTA-9014074", "name": "TXLNA (IL14) binds syntaxin4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10050140" ], "products": [ "species_10090029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10077843": { "compartment": "compartment_876", "id": "reaction_10077843", "reactome": "R-BTA-6787820", "name": "IL34 dimer binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077839", "species_10049981" ], "products": [ "species_10077841" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A7Z067", "ENSBTAT00000016977" ] }, "reaction_10077945": { "compartment": "compartment_17957", "id": "reaction_10077945", "reactome": "R-BTA-6790038", "name": "Expression of HSP90B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10060767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004364" ] }, "reaction_10077723": { "compartment": "compartment_70101", "id": "reaction_10077723", "reactome": "R-BTA-6786097", "name": "p-Y705-STAT3, p-Y641-STAT6 dimerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077719" ], "products": [ "species_10077721" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077870": { "compartment": "compartment_70101", "id": "reaction_10077870", "reactome": "R-BTA-6788622", "name": "p-Y-STATs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077866" ], "products": [ "species_10077868" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10077633": { "compartment": "compartment_876", "id": "reaction_10077633", "reactome": "R-BTA-6785762", "name": "IL13RA1 binds TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049908", "species_10077629" ], "products": [ "species_10077631" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015532", "ENSBTAT00000025754", "G3X7E9", "ENSBTAT00000025754", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10077874": { "compartment": "compartment_70101", "id": "reaction_10077874", "reactome": "R-BTA-6788623", "name": "p-Y-STATs translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077868" ], "products": [ "species_10077872" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077764": { "compartment": "compartment_70101", "id": "reaction_10077764", "reactome": "R-BTA-6786293", "name": "p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077721" ], "products": [ "species_10077762" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10052302": { "compartment": "compartment_70101", "id": "reaction_10052302", "reactome": "R-BTA-912734", "name": "CBL:CRKL binds RAPGEF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052298", "species_10039707" ], "products": [ "species_10052300" ], "modifiers": [], "additional_components": [ "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052323": { "compartment": "compartment_70101", "id": "reaction_10052323", "reactome": "R-BTA-912790", "name": "CBL binds CRK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052267", "species_10052296" ], "products": [ "species_10052298" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052294": { "compartment": "compartment_70101", "id": "reaction_10052294", "reactome": "R-BTA-912627", "name": "CBL ubiquitinates PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10052269" ], "products": [ "species_10052292" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10051962": { "compartment": "compartment_70101", "id": "reaction_10051962", "reactome": "R-BTA-879934", "name": "Recruitment of SHC1 is mediated by Y593 of the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051923", "species_10035544" ], "products": [ "species_10051960" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10051949": { "compartment": "compartment_70101", "id": "reaction_10051949", "reactome": "R-BTA-879909", "name": "Activation of STAT5a/b by JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051942", "species_113592" ], "products": [ "species_29370", "species_10051946" ], "modifiers": [ [ "species_10051942", "catalyst" ] ], "additional_components": [ "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10052735": { "compartment": "compartment_876", "id": "reaction_10052735", "reactome": "R-BTA-914036", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052238" ], "products": [ "species_10052732" ], "modifiers": [ [ "species_10052238", "catalyst" ] ], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051966": { "compartment": "compartment_876", "id": "reaction_10051966", "reactome": "R-BTA-879942", "name": "The receptor is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051964" ], "products": [ "species_10051921" ], "modifiers": [], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052321": { "compartment": "compartment_70101", "id": "reaction_10052321", "reactome": "R-BTA-912757", "name": "p-S585-IL3RB binds 14-3-3 proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037660", "species_10052317" ], "products": [ "species_10052319" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "P63103", "ENSBTAT00000000289" ] }, "reaction_10051936": { "compartment": "compartment_70101", "id": "reaction_10051936", "reactome": "R-BTA-879907", "name": "Tyrosine kinases phosphorylate the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051923" ], "modifiers": [ [ "species_10051933", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052240": { "compartment": "compartment_70101", "id": "reaction_10052240", "reactome": "R-BTA-909738", "name": "SHP1 and SHP2 bind the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047046", "species_10051923" ], "products": [ "species_10052238" ], "modifiers": [], "additional_components": [ "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051954": { "compartment": "compartment_70101", "id": "reaction_10051954", "reactome": "R-BTA-879910", "name": "JAK2 is phosphorylated, activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051951" ], "modifiers": [ [ "species_10051921", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052325": { "compartment": "compartment_984", "id": "reaction_10052325", "reactome": "R-BTA-913360", "name": "GM-CSF receptor alpha subunit binds GM-CSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050559", "species_10050555" ], "products": [ "species_10050561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002054", "ENSBTAT00000040022", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052327": { "compartment": "compartment_876", "id": "reaction_10052327", "reactome": "R-BTA-913371", "name": "GM-CSF receptor alpha:GM-CSF binds Bc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051911", "species_10050561" ], "products": [ "species_10051917" ], "modifiers": [], "additional_components": [ "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947" ] }, "reaction_10089466": { "compartment": "compartment_70101", "id": "reaction_10089466", "reactome": "R-BTA-8987084", "name": "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089459", "species_113592" ], "products": [ "species_10089463", "species_29370" ], "modifiers": [ [ "species_10089459", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089530": { "compartment": "compartment_70101", "id": "reaction_10089530", "reactome": "R-BTA-8987202", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089527", "species_113592" ], "products": [ "species_29370", "species_10089450" ], "modifiers": [ [ "species_10089527", "catalyst" ] ], "additional_components": [ "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10089523": { "compartment": "compartment_70101", "id": "reaction_10089523", "reactome": "R-BTA-8987179", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089520" ], "products": [ "species_10089490", "species_29370" ], "modifiers": [ [ "species_10089520", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089427": { "compartment": "compartment_459", "id": "reaction_10089427", "reactome": "R-BTA-8986985", "name": "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089417" ], "products": [ "species_29370", "species_10089424" ], "modifiers": [ [ "species_10089417", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089431": { "compartment": "compartment_70101", "id": "reaction_10089431", "reactome": "R-BTA-8987007", "name": "p-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087758" ], "products": [ "species_10089429" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089480": { "compartment": "compartment_70101", "id": "reaction_10089480", "reactome": "R-BTA-8987097", "name": "IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089476", "species_10046556" ], "products": [ "species_10089478" ], "modifiers": [], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089453": { "compartment": "compartment_70101", "id": "reaction_10089453", "reactome": "R-BTA-8987040", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089450" ], "products": [ "species_10089413", "species_29370" ], "modifiers": [ [ "species_10089450", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825" ] }, "reaction_10089516": { "compartment": "compartment_70101", "id": "reaction_10089516", "reactome": "R-BTA-8987150", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089478", "species_113592" ], "products": [ "species_29370", "species_10089513" ], "modifiers": [ [ "species_10089478", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089455": { "compartment": "compartment_70101", "id": "reaction_10089455", "reactome": "R-BTA-8987043", "name": "IL22RA1 binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050036", "species_10049950" ], "products": [ "species_10050038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001455", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089536": { "compartment": "compartment_70101", "id": "reaction_10089536", "reactome": "R-BTA-8987218", "name": "p-STAT1 dimer translocates from the cytosol to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089429" ], "products": [ "species_10089534" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089538": { "compartment": "compartment_70101", "id": "reaction_10089538", "reactome": "R-BTA-8987220", "name": "IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089518", "species_10089484" ], "products": [ "species_10089520" ], "modifiers": [], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089442": { "compartment": "compartment_70101", "id": "reaction_10089442", "reactome": "R-BTA-8987012", "name": "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089435" ], "products": [ "species_29370", "species_10089439" ], "modifiers": [ [ "species_10089435", "catalyst" ] ], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455", "F1MJR4", "ENSBTAT00000001455", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089506": { "compartment": "compartment_70101", "id": "reaction_10089506", "reactome": "R-BTA-8987120", "name": "JAK1 binds IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10049999" ], "products": [ "species_10050001" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000001456", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089540": { "compartment": "compartment_70101", "id": "reaction_10089540", "reactome": "R-BTA-8987266", "name": "IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089415", "species_10089413" ], "products": [ "species_10089417" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089444": { "compartment": "compartment_70101", "id": "reaction_10089444", "reactome": "R-BTA-8987033", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089424" ], "products": [ "species_10089413", "species_10089422" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089511": { "compartment": "compartment_70101", "id": "reaction_10089511", "reactome": "R-BTA-8987129", "name": "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089508", "species_113592" ], "products": [ "species_10089476", "species_29370" ], "modifiers": [ [ "species_10089508", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089446": { "compartment": "compartment_70101", "id": "reaction_10089446", "reactome": "R-BTA-8987039", "name": "JAK1 binds IL20RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10050044" ], "products": [ "species_10050046" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000066507", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10050054": { "compartment": "compartment_876", "id": "reaction_10050054", "reactome": "R-BTA-448744", "name": "IL20RA binds IL20RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050032", "species_10050046" ], "products": [ "species_10050048" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089542": { "compartment": "compartment_70101", "id": "reaction_10089542", "reactome": "R-BTA-8987270", "name": "p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089513" ], "products": [ "species_10089476", "species_10087758" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342" ] }, "reaction_10061449": { "compartment": "compartment_70101", "id": "reaction_10061449", "reactome": "R-BTA-1912382", "name": "Mature NOTCH heterodimer traffics to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061434" ], "products": [ "species_10061443" ], "modifiers": [ [ "species_10061447", "inhibitor" ] ], "additional_components": [ "G3X812", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "ENSBTAT00000084118" ] }, "reaction_10090834": { "compartment": "compartment_13231", "id": "reaction_10090834", "reactome": "R-BTA-9604308", "name": "NICD4 traffics to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090824" ], "products": [ "species_10044414" ], "modifiers": [ [ "species_10090832", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000050083", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "P63103", "ENSBTAT00000000289" ] }, "reaction_10078393": { "compartment": "compartment_5460", "id": "reaction_10078393", "reactome": "R-BTA-6793590", "name": "LIPT2 transfers octanoyl group to GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078383", "species_10076429" ], "products": [ "species_10038774", "species_10078386" ], "modifiers": [ [ "species_10078390", "catalyst" ] ], "additional_components": [ "CHEBI:25650", "G3X6L0", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000010820" ] }, "reaction_10052056": { "compartment": "compartment_5460", "id": "reaction_10052056", "reactome": "R-BTA-904864", "name": "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_904849", "species_379697" ], "products": [ "species_159549", "species_113557" ], "modifiers": [ [ "species_10052053", "catalyst" ] ], "additional_components": [ "F1MLG7", "ENSBTAT00000010113" ] }, "reaction_10047019": { "compartment": "compartment_17951", "id": "reaction_10047019", "reactome": "R-BTA-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389822" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078701": { "compartment": "compartment_70101", "id": "reaction_10078701", "reactome": "R-BTA-6798317", "name": "GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_29424" ], "products": [ "species_5359017", "species_71285" ], "modifiers": [ [ "species_10078698", "catalyst" ] ], "additional_components": [ "A0A3Q1LMP5", "ENSBTAT00000079667", "A0A3Q1M678", "ENSBTAT00000080669" ] }, "reaction_10047022": { "compartment": "compartment_17951", "id": "reaction_10047022", "reactome": "R-BTA-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_141343", "species_389678" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078366": { "compartment": "compartment_5460", "id": "reaction_10078366", "reactome": "R-BTA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078353", "species_10076427" ], "products": [ "species_10078359", "species_10076429" ], "modifiers": [ [ "species_10078363", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000005171" ] }, "reaction_10077458": { "compartment": "compartment_5460", "id": "reaction_10077458", "reactome": "R-BTA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10078402": { "compartment": "compartment_5460", "id": "reaction_10078402", "reactome": "R-BTA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10078386", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10076427" ], "modifiers": [ [ "species_10078399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "ENSBTAT00000008936", "Q5BIP7", "ENSBTAT00000019299", "CHEBI:49883" ] }, "reaction_10076441": { "compartment": "compartment_5460", "id": "reaction_10076441", "reactome": "R-BTA-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10076427" ], "products": [ "species_10076431", "species_29376" ], "modifiers": [ [ "species_10076438", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "P20821", "ENSBTAT00000008936", "CHEBI:14949", "E1BJQ1", "ENSBTAT00000036700" ] }, "reaction_10076459": { "compartment": "compartment_5460", "id": "reaction_10076459", "reactome": "R-BTA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10076443" ], "products": [ "species_113529", "species_29362", "species_10076427" ], "modifiers": [ [ "species_10076456", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000008936", "species_113596", "F1N206", "ENSBTAT00000033787" ] }, "reaction_10076450": { "compartment": "compartment_5460", "id": "reaction_10076450", "reactome": "R-BTA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10076431" ], "products": [ "species_5693978", "species_5693984", "species_10076443" ], "modifiers": [ [ "species_10076447", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:14949", "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000002992" ] }, "reaction_10051737": { "compartment": "compartment_70101", "id": "reaction_10051737", "reactome": "R-BTA-873918", "name": "Transphosphorylation of JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_113592" ], "products": [ "species_29370", "species_10051722" ], "modifiers": [ [ "species_10051716", "catalyst" ], [ "species_10043836", "inhibitor" ], [ "species_10051735", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "ENSBTAT00000077529", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10091723": { "compartment": "compartment_70101", "id": "reaction_10091723", "reactome": "R-BTA-9678561", "name": "IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678984", "species_10051743" ], "products": [ "species_10051778" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10051771": { "compartment": "compartment_70101", "id": "reaction_10051771", "reactome": "R-BTA-873922", "name": "Phosphorylation of STAT1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051760", "species_113592" ], "products": [ "species_29370", "species_10051768" ], "modifiers": [ [ "species_10051760", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051786": { "compartment": "compartment_70101", "id": "reaction_10051786", "reactome": "R-BTA-873927", "name": "Release of STAT1 dimer from active receptor unit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051784" ], "products": [ "species_10051756", "species_10051690" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051774": { "compartment": "compartment_70101", "id": "reaction_10051774", "reactome": "R-BTA-873924", "name": "Phosphorylation of IFNGR1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051722" ], "products": [ "species_29370", "species_10051756" ], "modifiers": [ [ "species_10051722", "catalyst" ] ], "additional_components": [ "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051696": { "compartment": "compartment_13231", "id": "reaction_10051696", "reactome": "R-BTA-873917", "name": "Translocation of STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051690" ], "products": [ "species_10051694" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10052067": { "compartment": "compartment_70101", "id": "reaction_10052067", "reactome": "R-BTA-909552", "name": "Phosphorylation of STAT1 at Ser727", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051768" ], "products": [ "species_29370", "species_10051784" ], "modifiers": [ [ "species_10052064", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10051762": { "compartment": "compartment_70101", "id": "reaction_10051762", "reactome": "R-BTA-873921", "name": "Binding of STAT1 to p-IFNGR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051758", "species_10051756" ], "products": [ "species_10051760" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051818": { "compartment": "compartment_7660", "id": "reaction_10051818", "reactome": "R-BTA-877281", "name": "PIAS1 binds p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051814", "species_10051796", "species_10051694" ], "products": [ "species_10051816" ], "modifiers": [], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "ENSBTAT00000083334", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ML58", "ENSBTAT00000083334", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456" ] }, "reaction_10055967": { "compartment": "compartment_7660", "id": "reaction_10055967", "reactome": "R-BTA-997326", "name": "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10051694" ], "products": [ "species_113550", "species_10055960" ], "modifiers": [ [ "species_10055964", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "ENSBTAT00000074168" ] }, "reaction_10051792": { "compartment": "compartment_70101", "id": "reaction_10051792", "reactome": "R-BTA-877269", "name": "SOCS-1 and SOCS-3 binds to p-JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_10051733" ], "products": [ "species_10051735" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051780": { "compartment": "compartment_984", "id": "reaction_10051780", "reactome": "R-BTA-873926", "name": "IFNG dimer binds IFNGR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051702", "species_10051743" ], "products": [ "species_10051745" ], "modifiers": [ [ "species_10051778", "inhibitor" ], [ "species_10051776", "inhibitor" ] ], "additional_components": [ "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051748": { "compartment": "compartment_70101", "id": "reaction_10051748", "reactome": "R-BTA-873919", "name": "Phosphorylation of JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051745" ], "products": [ "species_10051716", "species_29370" ], "modifiers": [ [ "species_10051745", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10078682": { "compartment": "compartment_876", "id": "reaction_10078682", "reactome": "R-BTA-6798258", "name": "PRTPRF, PTPRS, PTPRD bind LRRC4B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078678", "species_10046864" ], "products": [ "species_10078680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000043330", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "E1BPK8", "ENSBTAT00000043330" ] }, "reaction_10078674": { "compartment": "compartment_876", "id": "reaction_10078674", "reactome": "R-BTA-6798257", "name": "PTPRS binds NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046862", "species_10078670" ], "products": [ "species_10078672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074444", "ENSBTAT00000064547", "G3N3T6", "ENSBTAT00000064547", "A0A3Q1MZF8", "ENSBTAT00000074444" ] }, "reaction_10046868": { "compartment": "compartment_70101", "id": "reaction_10046868", "reactome": "R-BTA-388824", "name": "PTPRF, PTPRS, PTPRD bind Liprins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046854", "species_10046864" ], "products": [ "species_10046866" ], "modifiers": [], "additional_components": [ "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454" ] }, "reaction_10078566": { "compartment": "compartment_876", "id": "reaction_10078566", "reactome": "R-BTA-6797803", "name": "PTPRD binds SLITRK1-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078562", "species_10046858" ], "products": [ "species_10078564" ], "modifiers": [], "additional_components": [ "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827", "ENSBTAT00000066459", "A0A3Q1M422", "ENSBTAT00000066459", "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827" ] }, "reaction_10034944": { "compartment": "compartment_70101", "id": "reaction_10034944", "reactome": "R-BTA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10034941", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10036903": { "compartment": "compartment_70101", "id": "reaction_10036903", "reactome": "R-BTA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10034933", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10076792": { "compartment": "compartment_70101", "id": "reaction_10076792", "reactome": "R-BTA-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694568", "species_29356" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10076789", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022154" ] }, "reaction_10059002": { "compartment": "compartment_12045", "id": "reaction_10059002", "reactome": "R-BTA-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059853": { "compartment": "compartment_984", "id": "reaction_10059853", "reactome": "R-BTA-1602398", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602375", "species_109276" ], "products": [ "species_1602372", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10059004": { "compartment": "compartment_12045", "id": "reaction_10059004", "reactome": "R-BTA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10084526": { "compartment": "compartment_70101", "id": "reaction_10084526", "reactome": "R-BTA-8858298", "name": "HRASLS transfer acyl group from PC to PE to form NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_1500581" ], "products": [ "species_5694568", "species_6814253" ], "modifiers": [ [ "species_10084523", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451" ] }, "reaction_10058899": { "compartment": "compartment_12045", "id": "reaction_10058899", "reactome": "R-BTA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058885": { "compartment": "compartment_12045", "id": "reaction_10058885", "reactome": "R-BTA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058980": { "compartment": "compartment_12045", "id": "reaction_10058980", "reactome": "R-BTA-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10058977", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10046888": { "compartment": "compartment_876", "id": "reaction_10046888", "reactome": "R-BTA-388828", "name": "PD-1 binds B7DC and B7H1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046882", "species_10046872" ], "products": [ "species_10046884" ], "modifiers": [ [ "species_10046886", "inhibitor" ] ], "additional_components": [ "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165", "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10091743": { "compartment": "compartment_876", "id": "reaction_10091743", "reactome": "R-BTA-9679421", "name": "PDCD1 binds PDCD1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679406", "species_10046872" ], "products": [ "species_10046886" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10064439": { "compartment": "compartment_70101", "id": "reaction_10064439", "reactome": "R-BTA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10064584": { "compartment": "compartment_70101", "id": "reaction_10064584", "reactome": "R-BTA-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_2162081", "species_73473" ], "modifiers": [ [ "species_10034181", "catalyst" ] ], "additional_components": [ "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10075063": { "compartment": "compartment_70101", "id": "reaction_10075063", "reactome": "R-BTA-5686073", "name": "GRB2-1:SOS1 binds p-3Y-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050549", "species_10035491" ], "products": [ "species_10075061" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10086241": { "compartment": "compartment_7660", "id": "reaction_10086241", "reactome": "R-BTA-8878220", "name": "RUNX3 binds the NOTCH1 coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10086237" ], "products": [ "species_10086239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10072913": { "compartment": "compartment_876", "id": "reaction_10072913", "reactome": "R-BTA-5654148", "name": "p-4Y-PLCG1 dissociates from activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072911" ], "products": [ "species_10043237", "species_10065265" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072944": { "compartment": "compartment_70101", "id": "reaction_10072944", "reactome": "R-BTA-5654222", "name": "Activated FGFR3 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072941" ], "products": [ "species_29370", "species_10072911" ], "modifiers": [ [ "species_10072941", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10072946": { "compartment": "compartment_876", "id": "reaction_10072946", "reactome": "R-BTA-5654224", "name": "Activated FGFR3 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065265", "species_10061098" ], "products": [ "species_10072941" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10073152": { "compartment": "compartment_70101", "id": "reaction_10073152", "reactome": "R-BTA-5654634", "name": "Activated FGFR3 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073138", "species_113592" ], "products": [ "species_29370", "species_10073149" ], "modifiers": [ [ "species_10073138", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073140": { "compartment": "compartment_70101", "id": "reaction_10073140", "reactome": "R-BTA-5654625", "name": "Activated FGFR3 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065265" ], "products": [ "species_10073138" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073156": { "compartment": "compartment_876", "id": "reaction_10073156", "reactome": "R-BTA-5654646", "name": "Activated FGFR3:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073149" ], "products": [ "species_10073154" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073159": { "compartment": "compartment_70101", "id": "reaction_10073159", "reactome": "R-BTA-5654647", "name": "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073154", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073234": { "compartment": "compartment_70101", "id": "reaction_10073234", "reactome": "R-BTA-5654709", "name": "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065273", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073145": { "compartment": "compartment_876", "id": "reaction_10073145", "reactome": "R-BTA-5654631", "name": "Activated FGFR3 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073142", "species_113592" ], "products": [ "species_10065269", "species_29370" ], "modifiers": [ [ "species_10073142", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073019": { "compartment": "compartment_70101", "id": "reaction_10073019", "reactome": "R-BTA-5654413", "name": "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073016", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073147": { "compartment": "compartment_876", "id": "reaction_10073147", "reactome": "R-BTA-5654633", "name": "Activated FGFR3:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065267" ], "products": [ "species_10073142" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073021": { "compartment": "compartment_70101", "id": "reaction_10073021", "reactome": "R-BTA-5654416", "name": "Activated FGFR3:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065267" ], "products": [ "species_10073016" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10087376": { "compartment": "compartment_70101", "id": "reaction_10087376", "reactome": "R-BTA-8941628", "name": "Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065269", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073011": { "compartment": "compartment_876", "id": "reaction_10073011", "reactome": "R-BTA-5654408", "name": "Activated FGFR3 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073006" ], "products": [ "species_29370", "species_10065267" ], "modifiers": [ [ "species_10073006", "catalyst" ], [ "species_10073009", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073014": { "compartment": "compartment_70101", "id": "reaction_10073014", "reactome": "R-BTA-5654409", "name": "Activated FGFR3 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065265", "species_10072959" ], "products": [ "species_10073006" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10062984": { "compartment": "compartment_20699", "id": "reaction_10062984", "reactome": "R-BTA-2022860", "name": "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062948", "species_741440" ], "products": [ "species_742343", "species_10062971" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063610": { "compartment": "compartment_20699", "id": "reaction_10063610", "reactome": "R-BTA-2076508", "name": "HS2ST1 sulfates IdoA at C2 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063045", "species_741440" ], "products": [ "species_742343", "species_10063068" ], "modifiers": [ [ "species_10063607", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "ENSBTAT00000086518" ] }, "reaction_10063633": { "compartment": "compartment_20699", "id": "reaction_10063633", "reactome": "R-BTA-2076611", "name": "HS3STs sulfate GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063630", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VD21", "ENSBTAT00000085321", "E1B729", "ENSBTAT00000025630", "E1BKQ1", "ENSBTAT00000023123", "E1BNJ7", "ENSBTAT00000044024", "E1BP03", "ENSBTAT00000010350" ] }, "reaction_10063216": { "compartment": "compartment_17963", "id": "reaction_10063216", "reactome": "R-BTA-2024108", "name": "Some HSPGs are secreted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063132" ], "products": [ "species_10063214" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452" ] }, "reaction_10063603": { "compartment": "compartment_20699", "id": "reaction_10063603", "reactome": "R-BTA-2076419", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063114" ], "products": [ "species_742343", "species_10063130" ], "modifiers": [ [ "species_10063600", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LS54", "ENSBTAT00000078465", "A0A3Q1LTK3", "ENSBTAT00000075020" ] }, "reaction_10063010": { "compartment": "compartment_20699", "id": "reaction_10063010", "reactome": "R-BTA-2022887", "name": "NDST1-4 N-deacetylates GlcNAc residues in heparan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_10063007" ], "products": [ "species_10062948", "species_2022890" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063586": { "compartment": "compartment_17963", "id": "reaction_10063586", "reactome": "R-BTA-2076383", "name": "HS3ST1 sulfates GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063583", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VCB5", "ENSBTAT00000009799" ] }, "reaction_10051589": { "compartment": "compartment_20699", "id": "reaction_10051589", "reactome": "R-BTA-744231", "name": "SLC35D2 exchanges UDP-sugars for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744229", "species_735698" ], "products": [ "species_109402", "species_744234" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "species_29410", "species_914003", "species_29410", "species_914003", "ENSBTAT00000026562" ] }, "reaction_10084090": { "compartment": "compartment_70101", "id": "reaction_10084090", "reactome": "R-BTA-8853429", "name": "PHLDA1 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084084" ], "products": [ "species_10084088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084096": { "compartment": "compartment_70101", "id": "reaction_10084096", "reactome": "R-BTA-8853444", "name": "AURKA phosphorylates PHLDA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084088" ], "products": [ "species_10084086", "species_29370", "species_10084093" ], "modifiers": [ [ "species_10084088", "catalyst" ] ], "additional_components": [ "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590", "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10076112": { "compartment": "compartment_7660", "id": "reaction_10076112", "reactome": "R-BTA-5691381", "name": "MYSM1 deubiquitinates Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076107" ], "products": [ "species_10036828", "species_10076109" ], "modifiers": [ [ "species_10076107", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652" ] }, "reaction_10076119": { "compartment": "compartment_70101", "id": "reaction_10076119", "reactome": "R-BTA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539" ], "products": [ "species_10039537" ], "modifiers": [ [ "species_10076116", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "ENSBTAT00000046166" ] }, "reaction_10089947": { "compartment": "compartment_876", "id": "reaction_10089947", "reactome": "R-BTA-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089943", "species_10073483" ], "products": [ "species_10089945" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495" ] }, "reaction_10092364": { "compartment": "compartment_876", "id": "reaction_10092364", "reactome": "R-BTA-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073483" ], "products": [ "species_10092362" ], "modifiers": [], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438" ] }, "reaction_10089937": { "compartment": "compartment_70101", "id": "reaction_10089937", "reactome": "R-BTA-9013109", "name": "RHOC GEFs activate RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089932" ], "products": [ "species_29420", "species_10073483" ], "modifiers": [ [ "species_10089934", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LFQ5", "ENSBTAT00000066417", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LQ45", "ENSBTAT00000078928", "F1N2G5", "ENSBTAT00000002373", "F1MB21", "ENSBTAT00000017829" ] }, "reaction_10089952": { "compartment": "compartment_876", "id": "reaction_10089952", "reactome": "R-BTA-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073483" ], "products": [ "species_29372", "species_10089932" ], "modifiers": [ [ "species_10089949", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "E1BM23", "ENSBTAT00000038690", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092392": { "compartment": "compartment_12045", "id": "reaction_10092392", "reactome": "R-BTA-9714691", "name": "RAC3 binds ER effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092388", "species_10092384" ], "products": [ "species_10092390" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090330": { "compartment": "compartment_876", "id": "reaction_10090330", "reactome": "R-BTA-9018804", "name": "RAC3 GEFs activate RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090323" ], "products": [ "species_10090325", "species_29420" ], "modifiers": [ [ "species_10090327", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "A5PK69", "ENSBTAT00000079280", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10092394": { "compartment": "compartment_876", "id": "reaction_10092394", "reactome": "R-BTA-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090325" ], "products": [ "species_10092388" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090349": { "compartment": "compartment_876", "id": "reaction_10090349", "reactome": "R-BTA-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090341", "species_10090323" ], "products": [ "species_10090347" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "species_29420", "A5PK69", "ENSBTAT00000079280" ] }, "reaction_10090339": { "compartment": "compartment_876", "id": "reaction_10090339", "reactome": "R-BTA-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090325" ], "products": [ "species_29372", "species_10090323" ], "modifiers": [ [ "species_10090336", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29420", "F1N6V1", "ENSBTAT00000003400", "A4IF90", "ENSBTAT00000061453", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089930": { "compartment": "compartment_876", "id": "reaction_10089930", "reactome": "R-BTA-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089926", "species_10037315" ], "products": [ "species_10089928" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371" ] }, "reaction_10089149": { "compartment": "compartment_70101", "id": "reaction_10089149", "reactome": "R-BTA-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037315" ], "products": [ "species_29372", "species_10037313" ], "modifiers": [ [ "species_10089146", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29420", "Q08DB1", "ENSBTAT00000039899", "F1MGB9", "ENSBTAT00000052139", "A0A3Q1M2Q1", "ENSBTAT00000076617", "E1BI70", "ENSBTAT00000027682", "F1MYQ4", "ENSBTAT00000011665", "G3MXE8", "ENSBTAT00000066138", "E1BIM3", "ENSBTAT00000035838", "E1BM23", "ENSBTAT00000038690", "F1MWY5", "ENSBTAT00000023764", "F1N6V1", "ENSBTAT00000003400", "A4FV18", "ENSBTAT00000020147", "A0A3Q1LWV5", "ENSBTAT00000075058", "A0A3Q1LGT5", "ENSBTAT00000075956" ] }, "reaction_10089888": { "compartment": "compartment_12045", "id": "reaction_10089888", "reactome": "R-BTA-9013004", "name": "RHOA binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089862", "species_10089884" ], "products": [ "species_10089886" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089011": { "compartment": "compartment_70101", "id": "reaction_10089011", "reactome": "R-BTA-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10089008", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1MRV3", "ENSBTAT00000083879", "E1BH51", "ENSBTAT00000005514", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1M8D9", "ENSBTAT00000071999", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LNE2", "ENSBTAT00000077218", "E1BDY4", "ENSBTAT00000082024", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LFQ5", "ENSBTAT00000066417", "Q08DA6", "ENSBTAT00000011773", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1MA88", "ENSBTAT00000069507", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10089890": { "compartment": "compartment_876", "id": "reaction_10089890", "reactome": "R-BTA-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315" ], "products": [ "species_10089862" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089860": { "compartment": "compartment_70101", "id": "reaction_10089860", "reactome": "R-BTA-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313", "species_10089854" ], "products": [ "species_10089858" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "ENSBTAT00000007933", "A0A452DIS6", "ENSBTAT00000007933", "P61585", "ENSBTAT00000005600", "species_29420" ] }, "reaction_10090125": { "compartment": "compartment_70101", "id": "reaction_10090125", "reactome": "R-BTA-9014456", "name": "GDIs block activation of RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089854", "species_10090093" ], "products": [ "species_10090123" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007933", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29420", "A0A452DIS6", "ENSBTAT00000007933" ] }, "reaction_10090145": { "compartment": "compartment_12045", "id": "reaction_10090145", "reactome": "R-BTA-9014467", "name": "RHOG binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090117", "species_10090141" ], "products": [ "species_10090143" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090115": { "compartment": "compartment_876", "id": "reaction_10090115", "reactome": "R-BTA-9014449", "name": "RHOG binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090111", "species_10037305" ], "products": [ "species_10090113" ], "modifiers": [], "additional_components": [ "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570" ] }, "reaction_10090098": { "compartment": "compartment_876", "id": "reaction_10090098", "reactome": "R-BTA-9014433", "name": "RHOG GEFs activate RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090093" ], "products": [ "species_29420", "species_10037305" ], "modifiers": [ [ "species_10090095", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090103": { "compartment": "compartment_876", "id": "reaction_10090103", "reactome": "R-BTA-9014434", "name": "RHOG GAPs stimulate RHOG GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037305" ], "products": [ "species_29372", "species_10090093" ], "modifiers": [ [ "species_10090100", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10090119": { "compartment": "compartment_876", "id": "reaction_10090119", "reactome": "R-BTA-9014454", "name": "RHOG translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037305" ], "products": [ "species_10090117" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090089": { "compartment": "compartment_876", "id": "reaction_10090089", "reactome": "R-BTA-9014420", "name": "RAC2 translocates to the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10073712" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090091": { "compartment": "compartment_1222693", "id": "reaction_10090091", "reactome": "R-BTA-9014424", "name": "RAC2 binds effectors at the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090077": { "compartment": "compartment_70101", "id": "reaction_10090077", "reactome": "R-BTA-9014294", "name": "RAC2 binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299", "species_10090073" ], "products": [ "species_10090075" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092380": { "compartment": "compartment_12045", "id": "reaction_10092380", "reactome": "R-BTA-9714481", "name": "RAC2 binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092374", "species_10092376" ], "products": [ "species_10092378" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092382": { "compartment": "compartment_876", "id": "reaction_10092382", "reactome": "R-BTA-9714483", "name": "RAC2 translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092374" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090082": { "compartment": "compartment_70101", "id": "reaction_10090082", "reactome": "R-BTA-9014295", "name": "RAC2 GAPs stimulate RAC2 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037299" ], "products": [ "species_29372", "species_10090033" ], "modifiers": [ [ "species_10090079", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092370": { "compartment": "compartment_876", "id": "reaction_10092370", "reactome": "R-BTA-9714480", "name": "RAC2 translocates to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092368" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090087": { "compartment": "compartment_70101", "id": "reaction_10090087", "reactome": "R-BTA-9014296", "name": "RAC2 GEFs activate RAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090033" ], "products": [ "species_29420", "species_10037299" ], "modifiers": [ [ "species_10090084", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29420", "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1M4M7", "ENSBTAT00000071096", "A0A3Q1MKN5", "ENSBTAT00000080659", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090203": { "compartment": "compartment_876", "id": "reaction_10090203", "reactome": "R-BTA-9017491", "name": "RHOJ GEFs activate RHOJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090193" ], "products": [ "species_29420", "species_10090191" ], "modifiers": [ [ "species_10090200", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29420", "A4FV20", "ENSBTAT00000022858", "species_29438", "E1BNA6", "ENSBTAT00000002840" ] }, "reaction_10090198": { "compartment": "compartment_876", "id": "reaction_10090198", "reactome": "R-BTA-9017488", "name": "RHOJ GAPs stimulate RHOJ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090191" ], "products": [ "species_29372", "species_10090193" ], "modifiers": [ [ "species_10090195", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29438", "A4FV20", "ENSBTAT00000022858", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10091994": { "compartment": "compartment_70101", "id": "reaction_10091994", "reactome": "R-BTA-9696266", "name": "RND2 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091990", "species_10091948" ], "products": [ "species_10091992" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393", "F1MUP6", "ENSBTAT00000009719", "species_29438", "F1MUP6", "ENSBTAT00000009719", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393" ] }, "reaction_10092022": { "compartment": "compartment_70101", "id": "reaction_10092022", "reactome": "R-BTA-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091946" ], "products": [ "species_10091948" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009719", "F1MUP6", "ENSBTAT00000009719", "species_29438" ] }, "reaction_10091832": { "compartment": "compartment_876", "id": "reaction_10091832", "reactome": "R-BTA-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091827" ], "products": [ "species_29420", "species_10091829" ], "modifiers": [ [ "species_10091827", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29420", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420" ] }, "reaction_10091864": { "compartment": "compartment_876", "id": "reaction_10091864", "reactome": "R-BTA-9693125", "name": "RHOF binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091860", "species_10091829" ], "products": [ "species_10091862" ], "modifiers": [], "additional_components": [ "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393" ] }, "reaction_10091921": { "compartment": "compartment_876", "id": "reaction_10091921", "reactome": "R-BTA-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10091829" ], "products": [ "species_29372", "species_10091827" ], "modifiers": [ [ "species_10091918", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420", "F6RWK1", "ENSBTAT00000043933" ] }, "reaction_10090266": { "compartment": "compartment_70101", "id": "reaction_10090266", "reactome": "R-BTA-9018746", "name": "RHOQ binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090262", "species_10090239" ], "products": [ "species_10090264" ], "modifiers": [], "additional_components": [ "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391", "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438", "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391" ] }, "reaction_10090369": { "compartment": "compartment_876", "id": "reaction_10090369", "reactome": "R-BTA-9018836", "name": "RHOQ translocates to the Golgi-associated vesicle membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090239" ], "products": [ "species_10090367" ], "modifiers": [], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438" ] }, "reaction_10090246": { "compartment": "compartment_70101", "id": "reaction_10090246", "reactome": "R-BTA-9018745", "name": "RHOQ GAPs stimulate RHOQ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090239" ], "products": [ "species_29372", "species_10090241" ], "modifiers": [ [ "species_10090243", "catalyst" ] ], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29420", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092002": { "compartment": "compartment_70101", "id": "reaction_10092002", "reactome": "R-BTA-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091998" ], "products": [ "species_10092000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045869", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10092020": { "compartment": "compartment_70101", "id": "reaction_10092020", "reactome": "R-BTA-9696268", "name": "RND3 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092016", "species_10092000" ], "products": [ "species_10092018" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10063353": { "compartment": "compartment_70101", "id": "reaction_10063353", "reactome": "R-BTA-2029460", "name": "PAK1 phosphorylates LIMK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047644", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "ENSBTAT00000080749" ] }, "reaction_10073755": { "compartment": "compartment_70101", "id": "reaction_10073755", "reactome": "R-BTA-5668731", "name": "NOX3 complex:RAC1:GTP generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_352327" ], "products": [ "species_70106", "species_29366", "species_3299686" ], "modifiers": [ [ "species_10073752", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "E1BFF3", "ENSBTAT00000018021", "species_29438" ] }, "reaction_10091180": { "compartment": "compartment_70101", "id": "reaction_10091180", "reactome": "R-BTA-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091177" ], "products": [ "species_29370", "species_10091162" ], "modifiers": [ [ "species_10040565", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10091169": { "compartment": "compartment_70101", "id": "reaction_10091169", "reactome": "R-BTA-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091164", "species_10091162" ], "products": [ "species_10091166" ], "modifiers": [ [ "species_10091164", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022592", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "ENSBTAT00000022592" ] }, "reaction_10073731": { "compartment": "compartment_263698", "id": "reaction_10073731", "reactome": "R-BTA-5668629", "name": "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_29364" ], "products": [ "species_70106", "species_2000345", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ], [ "species_10073729", "catalyst" ], [ "species_1629751", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438", "species_74016", "P28782", "ENSBTAT00000066555", "species_140356", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10073716": { "compartment": "compartment_1222693", "id": "reaction_10073716", "reactome": "R-BTA-5668605", "name": "RAC2:GTP binds NOX2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10091175": { "compartment": "compartment_70101", "id": "reaction_10091175", "reactome": "R-BTA-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091166" ], "products": [ "species_10091173", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10063374": { "compartment": "compartment_70101", "id": "reaction_10063374", "reactome": "R-BTA-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043441", "species_10063372" ], "products": [ "species_10061166" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_29370", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "P63258", "ENSBTAT00000008132" ] }, "reaction_10073577": { "compartment": "compartment_70101", "id": "reaction_10073577", "reactome": "R-BTA-5667008", "name": "RHOA:GTP binds RHPN1 or RHPN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073573", "species_10037315" ], "products": [ "species_10073575" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073587", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LJH7", "ENSBTAT00000073587" ] }, "reaction_10072515": { "compartment": "compartment_70101", "id": "reaction_10072515", "reactome": "R-BTA-5625959", "name": "Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072511", "species_10072505" ], "products": [ "species_10072513" ], "modifiers": [], "additional_components": [ "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073842": { "compartment": "compartment_70101", "id": "reaction_10073842", "reactome": "R-BTA-5672083", "name": "KTN1 binds Kinesin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072513", "species_10055513" ], "products": [ "species_10073840" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073806": { "compartment": "compartment_876", "id": "reaction_10073806", "reactome": "R-BTA-5671993", "name": "CIT-3 binds DLG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073802", "species_10050472" ], "products": [ "species_10073804" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "ENSBTAT00000003326", "F1MM66", "ENSBTAT00000003326", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600" ] }, "reaction_10073796": { "compartment": "compartment_70101", "id": "reaction_10073796", "reactome": "R-BTA-5671970", "name": "Activated CIT binds KIF14 and PRC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073792", "species_10073788", "species_10073784" ], "products": [ "species_10073794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076885", "ENSBTAT00000029161", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "G5E5S3", "ENSBTAT00000029161", "Q2T9P1", "ENSBTAT00000076885" ] }, "reaction_10073561": { "compartment": "compartment_70101", "id": "reaction_10073561", "reactome": "R-BTA-5666001", "name": "Profilin:G-actin binds MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541", "species_10043459" ], "products": [ "species_10073543" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073503": { "compartment": "compartment_70101", "id": "reaction_10073503", "reactome": "R-BTA-5665761", "name": "FMNL3 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073499", "species_10073483" ], "products": [ "species_10073501" ], "modifiers": [], "additional_components": [ "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075" ] }, "reaction_10073525": { "compartment": "compartment_876", "id": "reaction_10073525", "reactome": "R-BTA-5665802", "name": "SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073521", "species_10073517" ], "products": [ "species_10073523" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068363", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LMM5", "ENSBTAT00000068363" ] }, "reaction_10073493": { "compartment": "compartment_876", "id": "reaction_10073493", "reactome": "R-BTA-5665748", "name": "FMNL2 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073489", "species_10073483" ], "products": [ "species_10073491" ], "modifiers": [], "additional_components": [ "A0A3Q1LSX9", "ENSBTAT00000073284", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LSX9", "ENSBTAT00000073284" ] }, "reaction_10073557": { "compartment": "compartment_7660", "id": "reaction_10073557", "reactome": "R-BTA-5665998", "name": "MKL1 binds SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068967", "species_10073553" ], "products": [ "species_10073555" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000016981", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073559": { "compartment": "compartment_70101", "id": "reaction_10073559", "reactome": "R-BTA-5665999", "name": "MKL1 translocates from cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541" ], "products": [ "species_10068967" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000070929" ] }, "reaction_10073547": { "compartment": "compartment_70101", "id": "reaction_10073547", "reactome": "R-BTA-5665982", "name": "RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073543", "species_10073539", "species_10073537" ], "products": [ "species_10073541", "species_10073545" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929", "A0A3Q1MSR1", "ENSBTAT00000069763", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000070929", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1MSR1", "ENSBTAT00000069763", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068939": { "compartment": "compartment_70101", "id": "reaction_10068939", "reactome": "R-BTA-3858495", "name": "DAAM1 recruits GTP-bound RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068935", "species_10068931" ], "products": [ "species_10068937" ], "modifiers": [], "additional_components": [ "species_29926", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "species_29926", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073549": { "compartment": "compartment_70101", "id": "reaction_10073549", "reactome": "R-BTA-5665989", "name": "DIAPH1 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315", "species_10073535" ], "products": [ "species_10073537" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073569": { "compartment": "compartment_7660", "id": "reaction_10073569", "reactome": "R-BTA-5666008", "name": "SCAI binds SRF:MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073555", "species_10073565" ], "products": [ "species_10073567" ], "modifiers": [], "additional_components": [ "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929", "ENSBTAT00000072829", "A0A3Q1M5I0", "ENSBTAT00000072829", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073507": { "compartment": "compartment_70101", "id": "reaction_10073507", "reactome": "R-BTA-5665767", "name": "Activated FMNL3 binds G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043459", "species_10073501" ], "products": [ "species_10073505" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10043461": { "compartment": "compartment_70101", "id": "reaction_10043461", "reactome": "R-BTA-203070", "name": "Association of profilin with monomeric actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043457", "species_10043441" ], "products": [ "species_10043459" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068933": { "compartment": "compartment_70101", "id": "reaction_10068933", "reactome": "R-BTA-3858489", "name": "ppDVL binds DAAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068929", "species_10068927" ], "products": [ "species_10068931" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000075877", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10092203": { "compartment": "compartment_263163", "id": "reaction_10092203", "reactome": "R-BTA-9706390", "name": "RHOBTB3 binds interacting proteins at trans-Golgi network", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092199", "species_10083329" ], "products": [ "species_10092201" ], "modifiers": [], "additional_components": [ "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10092205": { "compartment": "compartment_263163", "id": "reaction_10092205", "reactome": "R-BTA-9706393", "name": "RHOBTB3 binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083327" ], "products": [ "species_10083329" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080085", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10092208": { "compartment": "compartment_263163", "id": "reaction_10092208", "reactome": "R-BTA-9706399", "name": "RHOBTB3 hydrolyzes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083329" ], "products": [ "species_10083335", "species_29372" ], "modifiers": [ [ "species_10083329", "catalyst" ] ], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10071262": { "compartment": "compartment_13231", "id": "reaction_10071262", "reactome": "R-BTA-5252001", "name": "ATP1B4 binds SNW1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044442", "species_10071258" ], "products": [ "species_10071260" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010697", "ENSBTAT00000011740", "A7MB71", "ENSBTAT00000011740", "Q1JQE0", "ENSBTAT00000010697" ] }, "reaction_10064933": { "compartment": "compartment_7660", "id": "reaction_10064933", "reactome": "R-BTA-2186767", "name": "Degradation of ubiquitinated SKI/SKIL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064931" ], "products": [], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N727", "ENSBTAT00000060953", "E1BJ37", "ENSBTAT00000005438" ] }, "reaction_10043311": { "compartment": "compartment_876", "id": "reaction_10043311", "reactome": "R-BTA-202604", "name": "Formation of a heteromeric BMP receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042988", "species_10043000" ], "products": [ "species_10043002" ], "modifiers": [], "additional_components": [ "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282" ] }, "reaction_10084542": { "compartment": "compartment_984", "id": "reaction_10084542", "reactome": "R-BTA-8858346", "name": "AMHR2 binds AMH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084532", "species_10084538" ], "products": [ "species_10084540" ], "modifiers": [], "additional_components": [ "F1MZL1", "ENSBTAT00000019912", "E1BHR7", "ENSBTAT00000024657", "E1BHR7", "ENSBTAT00000024657", "F1MZL1", "ENSBTAT00000019912" ] }, "reaction_10042976": { "compartment": "compartment_70101", "id": "reaction_10042976", "reactome": "R-BTA-201445", "name": "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042969" ], "products": [], "modifiers": [ [ "species_10042973", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072746", "ENSBTAT00000043725" ] }, "reaction_10056354": { "compartment": "compartment_876", "id": "reaction_10056354", "reactome": "R-BTA-1181149", "name": "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056341", "species_113592" ], "products": [ "species_29370", "species_10056351" ], "modifiers": [ [ "species_10056341", "catalyst" ] ], "additional_components": [ "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665", "F1MSQ2", "ENSBTAT00000046665", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10056356": { "compartment": "compartment_876", "id": "reaction_10056356", "reactome": "R-BTA-1181153", "name": "Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056339", "species_10042992", "species_10045724" ], "products": [ "species_10056341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046665", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10068704": { "compartment": "compartment_70101", "id": "reaction_10068704", "reactome": "R-BTA-3772434", "name": "Phosphorylated DVL recruits PIP5K1B to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060420", "species_10043116" ], "products": [ "species_10068702" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080996", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10068707": { "compartment": "compartment_70101", "id": "reaction_10068707", "reactome": "R-BTA-3772436", "name": "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10068702", "catalyst" ] ], "additional_components": [ "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10067694": { "compartment": "compartment_7660", "id": "reaction_10067694", "reactome": "R-BTA-3322429", "name": "XIAP monoubiquinates TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10067672" ], "products": [ "species_10067691" ], "modifiers": [ [ "species_10067672", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067696": { "compartment": "compartment_7660", "id": "reaction_10067696", "reactome": "R-BTA-3322431", "name": "XIAP binds TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067670", "species_10067668" ], "products": [ "species_10067672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067698": { "compartment": "compartment_7660", "id": "reaction_10067698", "reactome": "R-BTA-3322434", "name": "XIAP dissociates from ub-TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067691" ], "products": [ "species_10067670", "species_10067689" ], "modifiers": [], "additional_components": [ "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289" ] }, "reaction_10068095": { "compartment": "compartment_70101", "id": "reaction_10068095", "reactome": "R-BTA-3640872", "name": "USP34 deubiquitinates AXIN1,AXIN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068083" ], "products": [ "species_10068071", "species_10033408" ], "modifiers": [ [ "species_10068092", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000078346" ] }, "reaction_10068073": { "compartment": "compartment_70101", "id": "reaction_10068073", "reactome": "R-BTA-3640844", "name": "RNF146 binds RibC-AXIN:TNKS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068054", "species_10068069" ], "products": [ "species_10068071" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10068088": { "compartment": "compartment_70101", "id": "reaction_10068088", "reactome": "R-BTA-3640862", "name": "Tankyrase binds AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041524", "species_10068067" ], "products": [ "species_10068075" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068078": { "compartment": "compartment_70101", "id": "reaction_10068078", "reactome": "R-BTA-3640858", "name": "Tankyrase ADP-ribosylates AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068075", "species_29360" ], "products": [ "species_197277", "species_10068069" ], "modifiers": [ [ "species_10068075", "catalyst" ] ], "additional_components": [ "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068086": { "compartment": "compartment_70101", "id": "reaction_10068086", "reactome": "R-BTA-3640861", "name": "RNF146 ubiquitinates ADP-ribosylated AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068071", "species_10033408" ], "products": [ "species_10068083" ], "modifiers": [ [ "species_10068071", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10067879": { "compartment": "compartment_7660", "id": "reaction_10067879", "reactome": "R-BTA-3364026", "name": "SET1 complex trimethylates H3K4 at the MYC gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10067848" ], "products": [ "species_77502", "species_10067852" ], "modifiers": [ [ "species_10067876", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "F1MHP8", "ENSBTAT00000012057", "E1BEP4", "ENSBTAT00000001294", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A4FUE3", "ENSBTAT00000021204", "E1BPF3", "ENSBTAT00000080372", "A0A3Q1M6V2", "ENSBTAT00000067448", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10071330": { "compartment": "compartment_984", "id": "reaction_10071330", "reactome": "R-BTA-5323545", "name": "Canonical WNT signaling through the atypical receptor RYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071326", "species_10071324" ], "products": [ "species_10071328" ], "modifiers": [], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000071795", "A0A3Q1N0Q2", "ENSBTAT00000071795", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10069645": { "compartment": "compartment_876", "id": "reaction_10069645", "reactome": "R-BTA-4641205", "name": "RSPO:LGR binds ZNRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069631", "species_10069641" ], "products": [ "species_10069643" ], "modifiers": [], "additional_components": [ "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069647": { "compartment": "compartment_876", "id": "reaction_10069647", "reactome": "R-BTA-4641206", "name": "RSPOs bind LGRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069615", "species_10069629" ], "products": [ "species_10069631" ], "modifiers": [], "additional_components": [ "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069664": { "compartment": "compartment_876", "id": "reaction_10069664", "reactome": "R-BTA-4641246", "name": "ZNRF3 autoubiquitinates to promote its internalization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069643" ], "products": [ "species_10069661" ], "modifiers": [ [ "species_10069643", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069607": { "compartment": "compartment_70101", "id": "reaction_10069607", "reactome": "R-BTA-4641147", "name": "DACT1 binds DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069603", "species_10043149" ], "products": [ "species_10069605" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025871", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MP88", "ENSBTAT00000025871" ] }, "reaction_10068923": { "compartment": "compartment_876", "id": "reaction_10068923", "reactome": "R-BTA-3858482", "name": "DVL is recruited to the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068919", "species_10068917" ], "products": [ "species_10068921" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069896": { "compartment": "compartment_876", "id": "reaction_10069896", "reactome": "R-BTA-5140741", "name": "WNT5A binds FZD and ROR receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069892", "species_10067196" ], "products": [ "species_10069894" ], "modifiers": [], "additional_components": [ "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10069882": { "compartment": "compartment_876", "id": "reaction_10069882", "reactome": "R-BTA-5138441", "name": "WNT5A-FZD4 recruits DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069874", "species_10043149" ], "products": [ "species_10069878" ], "modifiers": [], "additional_components": [ "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069876": { "compartment": "compartment_876", "id": "reaction_10069876", "reactome": "R-BTA-5099899", "name": "WNT5A binds FZD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069862", "species_10067196" ], "products": [ "species_10069874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061370", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069299": { "compartment": "compartment_70101", "id": "reaction_10069299", "reactome": "R-BTA-3965450", "name": "DAAM1 recruits PFN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068931", "species_10043451" ], "products": [ "species_10069297" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069448": { "compartment": "compartment_70101", "id": "reaction_10069448", "reactome": "R-BTA-4332358", "name": "Dissociation of CaM and CAMK2 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069445", "species_113592" ], "products": [ "species_29370", "species_10069441", "species_10037002" ], "modifiers": [ [ "species_10069445", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069456": { "compartment": "compartment_70101", "id": "reaction_10069456", "reactome": "R-BTA-4332359", "name": "Active calmodulin binds CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069452", "species_10037002" ], "products": [ "species_10069454" ], "modifiers": [], "additional_components": [ "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069459": { "compartment": "compartment_70101", "id": "reaction_10069459", "reactome": "R-BTA-4332363", "name": "Autophosphorylation and activation of CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069454" ], "products": [ "species_10069445", "species_29370" ], "modifiers": [ [ "species_10069454", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10067128": { "compartment": "compartment_20699", "id": "reaction_10067128", "reactome": "R-BTA-3247840", "name": "WLS binds WNT ligands in the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067122", "species_10066990" ], "products": [ "species_10067126" ], "modifiers": [], "additional_components": [ "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067200": { "compartment": "compartment_984", "id": "reaction_10067200", "reactome": "R-BTA-3247843", "name": "secretion of WNT ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10067198", "species_10067130" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "A0A3Q1M1A0", "ENSBTAT00000086580", "A6H6X8", "ENSBTAT00000018985", "E1BDG5", "ENSBTAT00000026930", "E1BKL2", "ENSBTAT00000035270", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "F1MHG3", "ENSBTAT00000017163", "A0A3Q1MPF5", "ENSBTAT00000081055", "A4D7S0", "ENSBTAT00000010650", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MEW8", "ENSBTAT00000012148", "F1MK64", "ENSBTAT00000020402", "F1N4C0", "ENSBTAT00000014355", "ENSBTAT00000077814" ] }, "reaction_10067202": { "compartment": "compartment_20699", "id": "reaction_10067202", "reactome": "R-BTA-3247844", "name": "WNT ligands traffic to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067126" ], "products": [ "species_10067168" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592" ] }, "reaction_10066994": { "compartment": "compartment_20699", "id": "reaction_10066994", "reactome": "R-BTA-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066988" ], "products": [ "species_10066992" ], "modifiers": [], "additional_components": [ "Q1RMH8", "ENSBTAT00000025026", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q1RMH8", "ENSBTAT00000025026", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239" ] }, "reaction_10068837": { "compartment": "compartment_383505", "id": "reaction_10068837", "reactome": "R-BTA-3781941", "name": "WNTs are secreted in exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068795" ], "products": [ "species_10068835" ], "modifiers": [], "additional_components": [ "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978" ] }, "reaction_10067124": { "compartment": "compartment_17963", "id": "reaction_10067124", "reactome": "R-BTA-3247837", "name": "WNT ligands traffic to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067086" ], "products": [ "species_10067122" ], "modifiers": [], "additional_components": [ "F1N6L8", "ENSBTAT00000002188", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1LVG1", "ENSBTAT00000068978", "A0A3Q1MQ82", "ENSBTAT00000083229", "A0A3Q1MJR6", "ENSBTAT00000085976", "F1MN70", "ENSBTAT00000018592", "E1BEN9", "ENSBTAT00000020414", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067204": { "compartment": "compartment_171062", "id": "reaction_10067204", "reactome": "R-BTA-3247847", "name": "WLS is endocytosed to the early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067130" ], "products": [ "species_10066982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077814", "ENSBTAT00000077814" ] }, "reaction_10068839": { "compartment": "compartment_876", "id": "reaction_10068839", "reactome": "R-BTA-3781943", "name": "WLS:WNT complex is internalized for maturation into exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10068795" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814" ] }, "reaction_10041640": { "compartment": "compartment_70101", "id": "reaction_10041640", "reactome": "R-BTA-195300", "name": "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041614" ], "products": [ "species_29370", "species_10041594" ], "modifiers": [ [ "species_10041614", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041629": { "compartment": "compartment_70101", "id": "reaction_10041629", "reactome": "R-BTA-195283", "name": "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041610" ], "products": [ "species_29370", "species_10041614" ], "modifiers": [ [ "species_10041610", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041647": { "compartment": "compartment_70101", "id": "reaction_10041647", "reactome": "R-BTA-195318", "name": "Phosphorylation of beta-catenin at Ser45 by CK1 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041644" ], "products": [ "species_10041634", "species_29370" ], "modifiers": [ [ "species_10041644", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041637": { "compartment": "compartment_70101", "id": "reaction_10041637", "reactome": "R-BTA-195287", "name": "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041634", "species_113592" ], "products": [ "species_29370", "species_10041610" ], "modifiers": [ [ "species_10041634", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063849": { "compartment": "compartment_70101", "id": "reaction_10063849", "reactome": "R-BTA-2130286", "name": "Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10063841" ], "products": [ "species_10063845" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10087597": { "compartment": "compartment_7660", "id": "reaction_10087597", "reactome": "R-BTA-8944349", "name": "TLE tetramers bind TCF/LEF at WNT promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067668", "species_10087593" ], "products": [ "species_10087595" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10071356": { "compartment": "compartment_7660", "id": "reaction_10071356", "reactome": "R-BTA-5334050", "name": "TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071346", "species_10071352" ], "products": [ "species_10071354" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1MAN6", "ENSBTAT00000079320" ] }, "reaction_10069651": { "compartment": "compartment_7660", "id": "reaction_10069651", "reactome": "R-BTA-4641229", "name": "TLE oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069649" ], "products": [ "species_10067668" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10041583": { "compartment": "compartment_70101", "id": "reaction_10041583", "reactome": "R-BTA-195251", "name": "Assembly of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041524", "species_10041570", "species_10041520", "species_10041566", "species_10041579" ], "products": [ "species_10041581" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "ENSBTAT00000087508", "ENSBTAT00000011639", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "ENSBTAT00000086393", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10070931": { "compartment": "compartment_70101", "id": "reaction_10070931", "reactome": "R-BTA-5229343", "name": "AXIN is phosphorylated in the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041581" ], "products": [ "species_10041590", "species_29370" ], "modifiers": [ [ "species_10041581", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063843": { "compartment": "compartment_70101", "id": "reaction_10063843", "reactome": "R-BTA-2130279", "name": "Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10041599" ], "products": [ "species_10063841" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10041604": { "compartment": "compartment_70101", "id": "reaction_10041604", "reactome": "R-BTA-195275", "name": "Phosphorylation of APC component of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041594" ], "products": [ "species_29370", "species_10041599" ], "modifiers": [ [ "species_10041594", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041606": { "compartment": "compartment_70101", "id": "reaction_10041606", "reactome": "R-BTA-195280", "name": "Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041599" ], "products": [ "species_10041599" ], "modifiers": [], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10060556": { "compartment": "compartment_876", "id": "reaction_10060556", "reactome": "R-BTA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060448": { "compartment": "compartment_876", "id": "reaction_10060448", "reactome": "R-BTA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060445", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10087531": { "compartment": "compartment_7660", "id": "reaction_10087531", "reactome": "R-BTA-8943817", "name": "MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087525", "species_10087523" ], "products": [ "species_10087529" ], "modifiers": [], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "A0A3Q1MWB8", "ENSBTAT00000079180" ] }, "reaction_10065099": { "compartment": "compartment_70101", "id": "reaction_10065099", "reactome": "R-BTA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043178", "species_179856" ], "products": [ "species_10065097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "species_6810412", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10065227": { "compartment": "compartment_70101", "id": "reaction_10065227", "reactome": "R-BTA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10043178" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036981": { "compartment": "compartment_7660", "id": "reaction_10036981", "reactome": "R-BTA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10036972" ], "products": [ "species_113582", "species_10036978" ], "modifiers": [ [ "species_10036972", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155" ] }, "reaction_10049478": { "compartment": "compartment_70101", "id": "reaction_10049478", "reactome": "R-BTA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10049470" ], "products": [ "species_113582", "species_10049475" ], "modifiers": [ [ "species_10049470", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10037022": { "compartment": "compartment_70101", "id": "reaction_10037022", "reactome": "R-BTA-111955", "name": "cAMP hydrolysis by Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037019", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318" ] }, "reaction_10037024": { "compartment": "compartment_70101", "id": "reaction_10037024", "reactome": "R-BTA-111956", "name": "Calmodulin activates Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037019" ], "products": [ "species_10037019" ], "modifiers": [ [ "species_10037002", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10037004": { "compartment": "compartment_876", "id": "reaction_10037004", "reactome": "R-BTA-111930", "name": "Adenylate cyclase produces cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10036997", "catalyst" ], [ "species_10037002", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10041863": { "compartment": "compartment_876", "id": "reaction_10041863", "reactome": "R-BTA-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041855" ], "products": [ "species_10041860", "species_29370" ], "modifiers": [ [ "species_10041855", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078659", "ENSBTAT00000078659", "ENSBTAT00000078659" ] }, "reaction_10063544": { "compartment": "compartment_70101", "id": "reaction_10063544", "reactome": "R-BTA-2064406", "name": "Translocation of YAP1:ZO-2 (TJP2) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063538" ], "products": [ "species_10063542" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10063550": { "compartment": "compartment_70101", "id": "reaction_10063550", "reactome": "R-BTA-2064417", "name": "WWTR1 (TAZ) binds ZO-1 (TJP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063546" ], "products": [ "species_10063548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000038824", "F1N2D3", "ENSBTAT00000038824", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063408": { "compartment": "compartment_70101", "id": "reaction_10063408", "reactome": "R-BTA-2038398", "name": "KIBRA (WWC1) binds LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063404", "species_10063259" ], "products": [ "species_10063406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019472", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "F1N3I6", "ENSBTAT00000019472" ] }, "reaction_10063568": { "compartment": "compartment_70101", "id": "reaction_10063568", "reactome": "R-BTA-2066299", "name": "DVL2 binds phosphorylated WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043149", "species_10063336" ], "products": [ "species_10063566" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078307", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10063346": { "compartment": "compartment_70101", "id": "reaction_10063346", "reactome": "R-BTA-2028735", "name": "AMOT proteins bind WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10063333" ], "products": [ "species_10063344" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063317": { "compartment": "compartment_70101", "id": "reaction_10063317", "reactome": "R-BTA-2028598", "name": "Phosphorylation of YAP by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063312" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063380": { "compartment": "compartment_70101", "id": "reaction_10063380", "reactome": "R-BTA-2032768", "name": "Translocation of WWTR1 (TAZ) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333" ], "products": [ "species_10063378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991" ] }, "reaction_10063319": { "compartment": "compartment_70101", "id": "reaction_10063319", "reactome": "R-BTA-2028626", "name": "Phosphorylated MOB1A proteins associate with LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063259", "species_10063273" ], "products": [ "species_10063275" ], "modifiers": [], "additional_components": [ "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063382": { "compartment": "compartment_70101", "id": "reaction_10063382", "reactome": "R-BTA-2032770", "name": "Translocation of YAP1 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276" ], "products": [ "species_10057280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112" ] }, "reaction_10063305": { "compartment": "compartment_70101", "id": "reaction_10063305", "reactome": "R-BTA-2028583", "name": "Phosphorylation of YAP by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063290" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063338": { "compartment": "compartment_70101", "id": "reaction_10063338", "reactome": "R-BTA-2028661", "name": "Phosphorylation of WWTR1 (TAZ) by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063342": { "compartment": "compartment_70101", "id": "reaction_10063342", "reactome": "R-BTA-2028724", "name": "AMOT proteins bind YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10057276" ], "products": [ "species_10063340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063534": { "compartment": "compartment_70101", "id": "reaction_10063534", "reactome": "R-BTA-2060328", "name": "Phosphorylation of WWTR1 (TAZ) by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063329": { "compartment": "compartment_70101", "id": "reaction_10063329", "reactome": "R-BTA-2028644", "name": "YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10063290" ], "products": [ "species_10063327" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10063554": { "compartment": "compartment_70101", "id": "reaction_10063554", "reactome": "R-BTA-2064418", "name": "WWTR1 (TAZ) binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063536" ], "products": [ "species_10063552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000069935", "A0A3Q1MEH9", "ENSBTAT00000069935", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063556": { "compartment": "compartment_70101", "id": "reaction_10063556", "reactome": "R-BTA-2064421", "name": "YAP1 binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063536", "species_10057276" ], "products": [ "species_10063538" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069935", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10043753": { "compartment": "compartment_70101", "id": "reaction_10043753", "reactome": "R-BTA-205075", "name": "JNK phosphorylates BIM, BAD and other targets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037714", "species_113592", "species_10037676" ], "products": [ "species_10043750", "species_29370", "species_10043747" ], "modifiers": [ [ "species_10039514", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000087439" ] }, "reaction_10041333": { "compartment": "compartment_13231", "id": "reaction_10041333", "reactome": "R-BTA-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039514" ], "products": [ "species_10039497" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10043739": { "compartment": "compartment_13231", "id": "reaction_10043739", "reactome": "R-BTA-204947", "name": "Polyubiquitinated NRIF migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043729" ], "products": [ "species_10043737" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119" ] }, "reaction_10043744": { "compartment": "compartment_70101", "id": "reaction_10043744", "reactome": "R-BTA-205008", "name": "Polyubiquitinated NRIF binds to p62 (Sequestosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043741", "species_10043723" ], "products": [ "species_10043729" ], "modifiers": [ [ "species_10043723", "catalyst" ] ], "additional_components": [ "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019" ] }, "reaction_10043778": { "compartment": "compartment_70101", "id": "reaction_10043778", "reactome": "R-BTA-205118", "name": "TRAF6 polyubiquitinates NRIF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043719", "species_10043727" ], "products": [ "species_10043741" ], "modifiers": [ [ "species_10043761", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000083119", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10043877": { "compartment": "compartment_70101", "id": "reaction_10043877", "reactome": "R-BTA-209536", "name": "IkB is ubiquitinated and degraded", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043858", "species_10033408" ], "products": [ "species_10043875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022183", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10041470": { "compartment": "compartment_876", "id": "reaction_10041470", "reactome": "R-BTA-194518", "name": "RhoA is activated by nucleotide exchange and inhibits axonal growth", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313" ], "products": [ "species_10037315" ], "modifiers": [ [ "species_10041467", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000083879" ] }, "reaction_10071524": { "compartment": "compartment_876", "id": "reaction_10071524", "reactome": "R-BTA-5357757", "name": "BIRC(cIAP1/2) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10071516" ], "products": [ "species_10071521" ], "modifiers": [ [ "species_10071516", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10071556": { "compartment": "compartment_70101", "id": "reaction_10071556", "reactome": "R-BTA-5357904", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071552", "species_10071521" ], "products": [ "species_10071554" ], "modifiers": [], "additional_components": [ "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670" ] }, "reaction_10071526": { "compartment": "compartment_876", "id": "reaction_10071526", "reactome": "R-BTA-5357780", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036142", "species_10071514" ], "products": [ "species_10071516" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10037964": { "compartment": "compartment_70101", "id": "reaction_10037964", "reactome": "R-BTA-140978", "name": "TRADD:TRAF2:RIP1 complex binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035378", "species_10036144" ], "products": [ "species_10037952" ], "modifiers": [ [ "species_10037962", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10067908": { "compartment": "compartment_984", "id": "reaction_10067908", "reactome": "R-BTA-3371385", "name": "TNF-alpha is cleaved by ADAM17 (TACE)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036154" ], "products": [ "species_10067885", "species_10067899" ], "modifiers": [ [ "species_10067905", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "species_29426", "E1B867", "ENSBTAT00000001519" ] }, "reaction_10092026": { "compartment": "compartment_70101", "id": "reaction_10092026", "reactome": "R-BTA-9697747", "name": "Caspase-8 and FLIP(L) processing at TNFR signaling complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067893" ], "products": [ "species_10092024", "species_10068040" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10092031": { "compartment": "compartment_70101", "id": "reaction_10092031", "reactome": "R-BTA-9697750", "name": "RIPK1 is cleaved by CASP8:FLIP(L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092024" ], "products": [ "species_10092028", "species_10071528" ], "modifiers": [ [ "species_10092024", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10071534": { "compartment": "compartment_70101", "id": "reaction_10071534", "reactome": "R-BTA-5357828", "name": "RIPK1 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952" ], "products": [ "species_10071532", "species_10071528" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "ENSBTAT00000008367", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10084723": { "compartment": "compartment_70101", "id": "reaction_10084723", "reactome": "R-BTA-8863101", "name": "SPPL2a/b cleaves TNF(1-76)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067899" ], "products": [ "species_10084710", "species_10084708" ], "modifiers": [ [ "species_10084720", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "ENSBTAT00000035815", "ENSBTAT00000035815", "A0A3Q1MBP7", "ENSBTAT00000077127", "E1BKF8", "ENSBTAT00000035792" ] }, "reaction_10071541": { "compartment": "compartment_70101", "id": "reaction_10071541", "reactome": "R-BTA-5357845", "name": "RIPK1 is deubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071521" ], "products": [ "species_10033408", "species_10071516" ], "modifiers": [ [ "species_10037962", "catalyst" ], [ "species_10071539", "catalyst" ] ], "additional_components": [ "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1NKI9", "ENSBTAT00000069028", "ENSBTAT00000026221" ] }, "reaction_10067895": { "compartment": "compartment_70101", "id": "reaction_10067895", "reactome": "R-BTA-3371360", "name": "FLIP(L) and procaspase-8 form heterodimer in TNF signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952", "species_10067887", "species_10035384" ], "products": [ "species_10067893" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322" ] }, "reaction_10035726": { "compartment": "compartment_876", "id": "reaction_10035726", "reactome": "R-BTA-75244", "name": "FASL binds FAS Receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033920", "species_10033916" ], "products": [ "species_10033922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014282", "ENSBTAT00000046575", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036146": { "compartment": "compartment_876", "id": "reaction_10036146", "reactome": "R-BTA-83586", "name": "FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035380", "species_10035384" ], "products": [ "species_10035386" ], "modifiers": [], "additional_components": [ "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036148": { "compartment": "compartment_876", "id": "reaction_10036148", "reactome": "R-BTA-83650", "name": "FasL:Fas binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033924", "species_10035378" ], "products": [ "species_10035380" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000024322", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10033926": { "compartment": "compartment_876", "id": "reaction_10033926", "reactome": "R-BTA-71050", "name": "Trimerization of the FASL:FAS receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033922" ], "products": [ "species_10033924" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10045016": { "compartment": "compartment_70101", "id": "reaction_10045016", "reactome": "R-BTA-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10045013", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "species_74016", "species_6797635", "E1BG59", "ENSBTAT00000029159" ] }, "reaction_10053213": { "compartment": "compartment_70101", "id": "reaction_10053213", "reactome": "R-BTA-939265", "name": "Activation of Rap1 by membrane-associated GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10047532", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10049279": { "compartment": "compartment_876", "id": "reaction_10049279", "reactome": "R-BTA-432110", "name": "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037443" ], "products": [ "species_10049276" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "ENSBTAT00000039221" ] }, "reaction_10049506": { "compartment": "compartment_876", "id": "reaction_10049506", "reactome": "R-BTA-443905", "name": "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049502" ], "products": [ "species_10049504" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10071673": { "compartment": "compartment_70101", "id": "reaction_10071673", "reactome": "R-BTA-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071670", "catalyst" ] ], "additional_components": [ "F1MFZ4", "ENSBTAT00000003769", "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10076840": { "compartment": "compartment_70101", "id": "reaction_10076840", "reactome": "R-BTA-5696101", "name": "ALDH8A1 oxidises 9cRAL to 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5362565", "species_29360" ], "products": [ "species_70106", "species_5362520", "species_73473" ], "modifiers": [ [ "species_10076837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010485" ] }, "reaction_10071691": { "compartment": "compartment_70101", "id": "reaction_10071691", "reactome": "R-BTA-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10071688", "catalyst" ] ], "additional_components": [ "F1MZD5", "ENSBTAT00000023493", "E1BM93", "ENSBTAT00000002535", "Q17QW3", "ENSBTAT00000006933" ] }, "reaction_10071659": { "compartment": "compartment_70101", "id": "reaction_10071659", "reactome": "R-BTA-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975622", "species_29360" ], "products": [ "species_70106", "species_5334816", "species_73473" ], "modifiers": [ [ "species_10071656", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661", "F1MHR3", "ENSBTAT00000012030" ] }, "reaction_10072397": { "compartment": "compartment_70101", "id": "reaction_10072397", "reactome": "R-BTA-5622134", "name": "CRABP1 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071664", "species_5334816" ], "products": [ "species_10071666" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017158", "species_215573", "P62964", "ENSBTAT00000017158" ] }, "reaction_10071678": { "compartment": "compartment_70101", "id": "reaction_10071678", "reactome": "R-BTA-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_29360" ], "products": [ "species_70106", "species_32737", "species_73473" ], "modifiers": [ [ "species_10071675", "catalyst" ] ], "additional_components": [ "Q27979", "ENSBTAT00000065932", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10072433": { "compartment": "compartment_70616", "id": "reaction_10072433", "reactome": "R-BTA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10072430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029403" ] }, "reaction_10072225": { "compartment": "compartment_70101", "id": "reaction_10072225", "reactome": "R-BTA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10071648": { "compartment": "compartment_70101", "id": "reaction_10071648", "reactome": "R-BTA-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071645", "catalyst" ] ], "additional_components": [ "Q8HYR6", "ENSBTAT00000005986", "Q0V8D0", "ENSBTAT00000001829", "Q8HZT6", "ENSBTAT00000026830" ] }, "reaction_10044211": { "compartment": "compartment_12045", "id": "reaction_10044211", "reactome": "R-BTA-211923", "name": "CYP26C1 4-hydroxylates 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5362520", "species_29368", "species_29364" ], "products": [ "species_5362524", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056396" ] }, "reaction_10071668": { "compartment": "compartment_70101", "id": "reaction_10071668", "reactome": "R-BTA-5362525", "name": "CYP26A1,B1,C1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10071666", "species_29368", "species_29364" ], "products": [ "species_29356", "species_10071664", "species_5362521", "species_29366" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "species_215573", "P62964", "ENSBTAT00000017158", "ENSBTAT00000017158", "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10071407": { "compartment": "compartment_7660", "id": "reaction_10071407", "reactome": "R-BTA-5334854", "name": "RAR:RXR binds SUMO-CRABP2:atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071399", "species_10071403" ], "products": [ "species_10071405" ], "modifiers": [], "additional_components": [ "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860" ] }, "reaction_10071397": { "compartment": "compartment_70101", "id": "reaction_10071397", "reactome": "R-BTA-5334827", "name": "SUMO-CRABP2 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071393", "species_5334816" ], "products": [ "species_10071395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158" ] }, "reaction_10072628": { "compartment": "compartment_7660", "id": "reaction_10072628", "reactome": "R-BTA-5634103", "name": "SUMO-CRABP2 dissociates from atRA:RAR:RXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071405" ], "products": [ "species_10072626", "species_10071401" ], "modifiers": [], "additional_components": [ "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "ENSBTAT00000087158" ] }, "reaction_10072630": { "compartment": "compartment_70101", "id": "reaction_10072630", "reactome": "R-BTA-5634104", "name": "SUMO-CRABP2:atRA translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071395" ], "products": [ "species_10071403" ], "modifiers": [], "additional_components": [ "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573" ] }, "reaction_10090456": { "compartment": "compartment_7660", "id": "reaction_10090456", "reactome": "R-BTA-9024334", "name": "Co-repressor complex dissociates from the transcription unit of the ABCA1 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090450" ], "products": [ "species_10090454", "species_10090444" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090559": { "compartment": "compartment_7660", "id": "reaction_10090559", "reactome": "R-BTA-9029551", "name": "NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090454", "species_10047785" ], "products": [ "species_10090557" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090563": { "compartment": "compartment_7660", "id": "reaction_10090563", "reactome": "R-BTA-9029561", "name": "NCOA1 recruits EP300 to the ABCA1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10090557" ], "products": [ "species_10090561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10090452": { "compartment": "compartment_7660", "id": "reaction_10090452", "reactome": "R-BTA-9024326", "name": "Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090448", "species_9024383" ], "products": [ "species_10090450" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090555": { "compartment": "compartment_7660", "id": "reaction_10090555", "reactome": "R-BTA-9029517", "name": "Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090551", "species_9024383" ], "products": [ "species_10090553" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090571": { "compartment": "compartment_7660", "id": "reaction_10090571", "reactome": "R-BTA-9029580", "name": "NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090565", "species_10047785" ], "products": [ "species_10090569" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090567": { "compartment": "compartment_7660", "id": "reaction_10090567", "reactome": "R-BTA-9029566", "name": "Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090553" ], "products": [ "species_10044694", "species_10090565" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090712": { "compartment": "compartment_7660", "id": "reaction_10090712", "reactome": "R-BTA-9038029", "name": "27-hydroxysterol binds ESR1, ESR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045570", "species_9024328" ], "products": [ "species_10090710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005899", "species_9024328", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10092314": { "compartment": "compartment_7660", "id": "reaction_10092314", "reactome": "R-BTA-9709547", "name": "ESTG binds ESR2:chaperone complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086682", "species_1254400" ], "products": [ "species_10086684" ], "modifiers": [], "additional_components": [ "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180", "species_1254400", "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180" ] }, "reaction_10089761": { "compartment": "compartment_7660", "id": "reaction_10089761", "reactome": "R-BTA-9011981", "name": "EP300 is recruited to MYC and BCL2 genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10089757" ], "products": [ "species_10089759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10091115": { "compartment": "compartment_876", "id": "reaction_10091115", "reactome": "R-BTA-9624272", "name": "MMPs cleave HB-EGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091106" ], "products": [ "species_10091108", "species_10040221" ], "modifiers": [ [ "species_10091110", "catalyst" ], [ "species_10091113", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000029015", "ENSBTAT00000029015", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10091275": { "compartment": "compartment_876", "id": "reaction_10091275", "reactome": "R-BTA-9632918", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091269" ], "products": [ "species_10091273" ], "modifiers": [], "additional_components": [ "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091260": { "compartment": "compartment_876", "id": "reaction_10091260", "reactome": "R-BTA-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091252", "species_113592" ], "products": [ "species_29370", "species_10091257" ], "modifiers": [ [ "species_10091252", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10091271": { "compartment": "compartment_876", "id": "reaction_10091271", "reactome": "R-BTA-9632906", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040312", "species_10091257" ], "products": [ "species_10091269" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10091151": { "compartment": "compartment_876", "id": "reaction_10091151", "reactome": "R-BTA-9625482", "name": "PTK2 binds activated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043033" ], "products": [ "species_10091149" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000085237", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091156": { "compartment": "compartment_876", "id": "reaction_10091156", "reactome": "R-BTA-9625487", "name": "PTK2 autophosphorylates downstream of EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091149" ], "products": [ "species_29370", "species_10091153" ], "modifiers": [ [ "species_10091149", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091118": { "compartment": "compartment_7660", "id": "reaction_10091118", "reactome": "R-BTA-9624527", "name": "AKT-phosphorylated FOXO3 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042685" ], "products": [ "species_10091011" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10091267": { "compartment": "compartment_7660", "id": "reaction_10091267", "reactome": "R-BTA-9632873", "name": "p-S10 CDKN1B translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091263" ], "products": [ "species_10091265" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "ENSBTAT00000017629" ] }, "reaction_10091158": { "compartment": "compartment_876", "id": "reaction_10091158", "reactome": "R-BTA-9625813", "name": "S1P binds S1PR3 in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5218688", "species_10046309" ], "products": [ "species_10091113" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015111", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10086662": { "compartment": "compartment_7660", "id": "reaction_10086662", "reactome": "R-BTA-8939201", "name": "ESR dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086658" ], "products": [ "species_10086660" ], "modifiers": [], "additional_components": [ "species_1254400", "Q9XSB5", "ENSBTAT00000005899", "species_1254400", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10086575": { "compartment": "compartment_984", "id": "reaction_10086575", "reactome": "R-BTA-8937631", "name": "CRHR2-2 binds CRH,UCN,UCN2,UCN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10086571" ], "products": [ "species_10086573" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10048270": { "compartment": "compartment_984", "id": "reaction_10048270", "reactome": "R-BTA-420173", "name": "CRHR1,CRHR2-1 binds CRH,UCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10048266" ], "products": [ "species_10048268" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10049681": { "compartment": "compartment_984", "id": "reaction_10049681", "reactome": "R-BTA-444773", "name": "EGF-TM7 receptors bind chondroitin sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444761", "species_10049677" ], "products": [ "species_10049679" ], "modifiers": [], "additional_components": [ "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "species_444761" ] }, "reaction_10051907": { "compartment": "compartment_876", "id": "reaction_10051907", "reactome": "R-BTA-879674", "name": "CD97 binds CD55", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049671", "species_10051903" ], "products": [ "species_10051905" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081916", "ENSBTAT00000078403", "A0A3Q1LQX2", "ENSBTAT00000078403", "A0A3Q1M0R0", "ENSBTAT00000081916" ] }, "reaction_10086565": { "compartment": "compartment_984", "id": "reaction_10086565", "reactome": "R-BTA-8937613", "name": "CRHBP binds CRH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086561", "species_10048266" ], "products": [ "species_10086563" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026905", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A7MBA3", "ENSBTAT00000026905" ] }, "reaction_10048248": { "compartment": "compartment_984", "id": "reaction_10048248", "reactome": "R-BTA-420123", "name": "Glucagon-like receptor 2 binds GLP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048244", "species_10048242" ], "products": [ "species_10048246" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000006662", "E1BAY1", "ENSBTAT00000006662", "P01272", "ENSBTAT00000000972" ] }, "reaction_10048282": { "compartment": "compartment_984", "id": "reaction_10048282", "reactome": "R-BTA-420202", "name": "Secretin receptor binds secretin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048278", "species_10048274" ], "products": [ "species_10048280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071185", "ENSBTAT00000079270", "A0A3Q1MB83", "ENSBTAT00000079270", "A0A3Q1M5G0", "ENSBTAT00000071185" ] }, "reaction_10048304": { "compartment": "compartment_984", "id": "reaction_10048304", "reactome": "R-BTA-420233", "name": "VIP receptors bind VIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048290", "species_10048300" ], "products": [ "species_10048302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017827", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "P81401", "ENSBTAT00000017827" ] }, "reaction_10038918": { "compartment": "compartment_984", "id": "reaction_10038918", "reactome": "R-BTA-163625", "name": "Glucagon binds to Glucagon receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038912", "species_10038908" ], "products": [ "species_10038916" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "ENSBTAT00000000972", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10048326": { "compartment": "compartment_984", "id": "reaction_10048326", "reactome": "R-BTA-420489", "name": "Parathyroid hormone receptor can bind parathyroid hormone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048322", "species_10048312" ], "products": [ "species_10048324" ], "modifiers": [], "additional_components": [ "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408", "ENSBTAT00000061196", "E1B7Q8", "ENSBTAT00000061196", "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408" ] }, "reaction_10091763": { "compartment": "compartment_984", "id": "reaction_10091763", "reactome": "R-BTA-9684627", "name": "CYSLTR1 binds CYSLTR1 antagonists", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_9684615" ], "products": [ "species_10091761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047378": { "compartment": "compartment_984", "id": "reaction_10047378", "reactome": "R-BTA-391937", "name": "UDP/CysLT receptor can bind cysteinyl leukotrienes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_416372" ], "products": [ "species_10046259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047396": { "compartment": "compartment_984", "id": "reaction_10047396", "reactome": "R-BTA-391941", "name": "BLT receptors can bind LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045934", "species_416436" ], "products": [ "species_10045936" ], "modifiers": [], "additional_components": [ "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992" ] }, "reaction_10091812": { "compartment": "compartment_984", "id": "reaction_10091812", "reactome": "R-BTA-9690439", "name": "CYSLTR1 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_416372" ], "products": [ "species_10045864" ], "modifiers": [ [ "species_10091761", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034352", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047398": { "compartment": "compartment_984", "id": "reaction_10047398", "reactome": "R-BTA-391943", "name": "CYSLT2 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038914", "species_416372" ], "products": [ "species_10045866" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10047374": { "compartment": "compartment_984", "id": "reaction_10047374", "reactome": "R-BTA-391935", "name": "DP1 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416911", "species_10047370" ], "products": [ "species_10047372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008808", "A0A452DI56", "ENSBTAT00000008808", "species_416911" ] }, "reaction_10047376": { "compartment": "compartment_984", "id": "reaction_10047376", "reactome": "R-BTA-391936", "name": "EP1 receptor can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10045990" ], "products": [ "species_10045992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046806", "species_391930", "F1MUY4", "ENSBTAT00000046806" ] }, "reaction_10047394": { "compartment": "compartment_984", "id": "reaction_10047394", "reactome": "R-BTA-391940", "name": "EP2 and EP4 receptors can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10047390" ], "products": [ "species_10047392" ], "modifiers": [], "additional_components": [ "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "species_391930" ] }, "reaction_10047380": { "compartment": "compartment_984", "id": "reaction_10047380", "reactome": "R-BTA-391939", "name": "TP receptor can bind thromboxane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391932", "species_10045856" ], "products": [ "species_10045858" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10047366": { "compartment": "compartment_984", "id": "reaction_10047366", "reactome": "R-BTA-391934", "name": "DP2 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046263", "species_416911" ], "products": [ "species_10046265" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066986", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986" ] }, "reaction_10047364": { "compartment": "compartment_984", "id": "reaction_10047364", "reactome": "R-BTA-391905", "name": "Oxoeicosanoid receptor can bind oxoeicosanoid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416428", "species_10046299" ], "products": [ "species_10046301" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005326", "F1MCJ0", "ENSBTAT00000005326", "species_416428" ] }, "reaction_10049657": { "compartment": "compartment_984", "id": "reaction_10049657", "reactome": "R-BTA-444654", "name": "G-protein coupled bile acid receptor binds lithocholic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444840", "species_10049653" ], "products": [ "species_10049655" ], "modifiers": [], "additional_components": [ "species_5357505", "species_193451", "species_176655", "CHEBI:16755", "ENSBTAT00000005120", "Q862A9", "ENSBTAT00000005120", "species_5357505", "species_193451", "species_176655", "CHEBI:16755" ] }, "reaction_10047354": { "compartment": "compartment_984", "id": "reaction_10047354", "reactome": "R-BTA-391375", "name": "Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047350", "species_10047338" ], "products": [ "species_10047352" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524", "ENSBTAT00000052615", "F1N4F6", "ENSBTAT00000052615", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524" ] }, "reaction_10047362": { "compartment": "compartment_984", "id": "reaction_10047362", "reactome": "R-BTA-391377", "name": "Luteinizing hormone receptor can bind LH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041267", "species_10047358" ], "products": [ "species_10047360" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000022047", "A0A140T893", "ENSBTAT00000022047", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10047334": { "compartment": "compartment_984", "id": "reaction_10047334", "reactome": "R-BTA-391372", "name": "Gonadotropin-releasing hormone receptors can bind GNRH I and II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045798", "species_10045788" ], "products": [ "species_10045800" ], "modifiers": [], "additional_components": [ "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "ENSBTAT00000000559", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568" ] }, "reaction_10049659": { "compartment": "compartment_984", "id": "reaction_10049659", "reactome": "R-BTA-444661", "name": "HCAR2 binds HCAR2 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296262", "species_10046459" ], "products": [ "species_10046461" ], "modifiers": [], "additional_components": [ "CHEBI:20067", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230" ] }, "reaction_10048208": { "compartment": "compartment_984", "id": "reaction_10048208", "reactome": "R-BTA-419841", "name": "Light stimulates opsin receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10048204" ], "products": [ "species_10048206" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10048214": { "compartment": "compartment_984", "id": "reaction_10048214", "reactome": "R-BTA-419861", "name": "Melanospin is stimulated by light", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10045850" ], "products": [ "species_10045852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040059", "E1BEK2", "ENSBTAT00000040059", "species_419777" ] }, "reaction_10045180": { "compartment": "compartment_984", "id": "reaction_10045180", "reactome": "R-BTA-373339", "name": "Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045172", "species_10045176" ], "products": [ "species_10045178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013116", "ENSBTAT00000026663", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116" ] }, "reaction_10067358": { "compartment": "compartment_876", "id": "reaction_10067358", "reactome": "R-BTA-3296301", "name": "CCRL2 binds CCL19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049514", "species_10067354" ], "products": [ "species_10067356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016850", "ENSBTAT00000008096", "Q0II78", "ENSBTAT00000008096", "Q3ZBN3", "ENSBTAT00000016850" ] }, "reaction_10045168": { "compartment": "compartment_984", "id": "reaction_10045168", "reactome": "R-BTA-373087", "name": "Receptor CCR6 binds CCL20 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045164", "species_10045160" ], "products": [ "species_10045166" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028430", "ENSBTAT00000037034", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430" ] }, "reaction_10045072": { "compartment": "compartment_984", "id": "reaction_10045072", "reactome": "R-BTA-373061", "name": "Receptors CCR3, 4 and 5 bind CCL5 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045054", "species_10045068" ], "products": [ "species_10045070" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082438", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438" ] }, "reaction_10049520": { "compartment": "compartment_984", "id": "reaction_10049520", "reactome": "R-BTA-443978", "name": "Receptor CCR11 binds CCL19, CCL21 & CCL25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049510", "species_10049516" ], "products": [ "species_10049518" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026082", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "P35350", "ENSBTAT00000026082" ] }, "reaction_10045106": { "compartment": "compartment_984", "id": "reaction_10045106", "reactome": "R-BTA-373074", "name": "Receptor CCR9 binds CCL25 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045102", "species_10045098" ], "products": [ "species_10045104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078248", "ENSBTAT00000007331", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248" ] }, "reaction_10045268": { "compartment": "compartment_984", "id": "reaction_10045268", "reactome": "R-BTA-374214", "name": "Receptors CXCR4 and 7 bind CXCL12 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045264", "species_10045260" ], "products": [ "species_10045266" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980" ] }, "reaction_10083880": { "compartment": "compartment_876", "id": "reaction_10083880", "reactome": "R-BTA-8851352", "name": "CCR8 binds CCL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046469", "species_10045080" ], "products": [ "species_10046471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047653", "ENSBTAT00000020577", "F6RDR3", "ENSBTAT00000020577", "E1BAG6", "ENSBTAT00000047653" ] }, "reaction_10045196": { "compartment": "compartment_984", "id": "reaction_10045196", "reactome": "R-BTA-373358", "name": "Receptor CXCR6 binds CXCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045188", "species_10045192" ], "products": [ "species_10045194" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020855", "ENSBTAT00000024371", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855" ] }, "reaction_10045280": { "compartment": "compartment_984", "id": "reaction_10045280", "reactome": "R-BTA-374248", "name": "Receptor CXCR3 binds ligands CXCL9 to 11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045276", "species_10045272" ], "products": [ "species_10045278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019690", "ENSBTAT00000075648", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690" ] }, "reaction_10049570": { "compartment": "compartment_984", "id": "reaction_10049570", "reactome": "R-BTA-443986", "name": "Receptor ACKR2 binds most inflammatory CC chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049524", "species_10049566" ], "products": [ "species_10049568" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068509", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "A0A3Q1LTZ4", "ENSBTAT00000068509" ] }, "reaction_10045156": { "compartment": "compartment_984", "id": "reaction_10045156", "reactome": "R-BTA-373086", "name": "Receptor CCR10 binds CCL27 and 28 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045142", "species_10045152" ], "products": [ "species_10045154" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025420", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420" ] }, "reaction_10049639": { "compartment": "compartment_984", "id": "reaction_10049639", "reactome": "R-BTA-444523", "name": "CXCR5 binds CXCL13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046161", "species_10046157" ], "products": [ "species_10046163" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011164", "ENSBTAT00000063808", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164" ] }, "reaction_10045094": { "compartment": "compartment_984", "id": "reaction_10045094", "reactome": "R-BTA-373073", "name": "Receptors CCR1, 2 and 8 bind CCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045090", "species_10045086" ], "products": [ "species_10045092" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079349", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349" ] }, "reaction_10091037": { "compartment": "compartment_984", "id": "reaction_10091037", "reactome": "R-BTA-9615249", "name": "ARBs bind AGRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9615246", "species_10045250" ], "products": [ "species_10091035" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063575", "P25104", "ENSBTAT00000063575" ] }, "reaction_10046731": { "compartment": "compartment_984", "id": "reaction_10046731", "reactome": "R-BTA-388468", "name": "AVP(20-28) binds AVPR1A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10045810" ], "products": [ "species_10045816" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10047483": { "compartment": "compartment_984", "id": "reaction_10047483", "reactome": "R-BTA-392263", "name": "AVP(20-28) binds AVPR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10047479" ], "products": [ "species_10047481" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "ENSBTAT00000065044", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10046733": { "compartment": "compartment_984", "id": "reaction_10046733", "reactome": "R-BTA-388503", "name": "Oxytocin receptor bind oxytocin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045970", "species_10045966" ], "products": [ "species_10045972" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026346", "ENSBTAT00000010554", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346" ] }, "reaction_10049661": { "compartment": "compartment_984", "id": "reaction_10049661", "reactome": "R-BTA-444691", "name": "Prokineticin receptors bind prokineticin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046036", "species_10046032" ], "products": [ "species_10046038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013959", "ENSBTAT00000021097", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959" ] }, "reaction_10046729": { "compartment": "compartment_984", "id": "reaction_10046729", "reactome": "R-BTA-383373", "name": "Tachykinin receptor 3 (NK3) binds to neurokinin B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045940", "species_10045944" ], "products": [ "species_10045946" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029067", "ENSBTAT00000021612", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067" ] }, "reaction_10045406": { "compartment": "compartment_984", "id": "reaction_10045406", "reactome": "R-BTA-374787", "name": "GPCR neuropeptide receptor binds neuropeptides B and W", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045398", "species_10045402" ], "products": [ "species_10045404" ], "modifiers": [], "additional_components": [ "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "ENSBTAT00000021510", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382" ] }, "reaction_10045362": { "compartment": "compartment_984", "id": "reaction_10045362", "reactome": "R-BTA-374723", "name": "Nociceptin receptor binds to nociceptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045358", "species_10045354" ], "products": [ "species_10045360" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084136", "ENSBTAT00000000695", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136" ] }, "reaction_10046773": { "compartment": "compartment_984", "id": "reaction_10046773", "reactome": "R-BTA-388605", "name": "POMC(138-176) binds MC2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046769", "species_10046767" ], "products": [ "species_10046771" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010386", "ENSBTAT00000014661", "P34974", "ENSBTAT00000014661", "P01190", "ENSBTAT00000010386" ] }, "reaction_10045332": { "compartment": "compartment_984", "id": "reaction_10045332", "reactome": "R-BTA-374331", "name": "Bradykinin receptors B1 and B2 bind to bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038198", "species_10045328" ], "products": [ "species_10045330" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053071", "ENSBTAT00000078035", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071" ] }, "reaction_10053335": { "compartment": "compartment_876", "id": "reaction_10053335", "reactome": "R-BTA-964800", "name": "Neuromedin-U receptors bind neuromedins U, S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046114", "species_10046110" ], "products": [ "species_10046116" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061371", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371" ] }, "reaction_10054775": { "compartment": "compartment_876", "id": "reaction_10054775", "reactome": "R-BTA-981832", "name": "NMUR2 binds neuromedin-S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046102", "species_10046098" ], "products": [ "species_10046104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048447", "ENSBTAT00000014782", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447" ] }, "reaction_10046953": { "compartment": "compartment_984", "id": "reaction_10046953", "reactome": "R-BTA-389463", "name": "Proteinase-activated receptors can bind thrombin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045984", "species_10037577" ], "products": [ "species_10045986" ], "modifiers": [], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191" ] }, "reaction_10045384": { "compartment": "compartment_984", "id": "reaction_10045384", "reactome": "R-BTA-374758", "name": "Somatostatin receptors bind somatostatin and cortistatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045366", "species_10045380" ], "products": [ "species_10045382" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063299", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299" ] }, "reaction_10046763": { "compartment": "compartment_984", "id": "reaction_10046763", "reactome": "R-BTA-388596", "name": "Melanocortin receptors bind melanocortins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046759", "species_10046737" ], "products": [ "species_10046761" ], "modifiers": [], "additional_components": [ "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049", "ENSBTAT00000010386", "P01190", "ENSBTAT00000010386", "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049" ] }, "reaction_10049645": { "compartment": "compartment_984", "id": "reaction_10049645", "reactome": "R-BTA-444620", "name": "Neuropeptide S receptor binds neuropeptide S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046022", "species_10046026" ], "products": [ "species_10046028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067360", "ENSBTAT00000018290", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360" ] }, "reaction_10049699": { "compartment": "compartment_984", "id": "reaction_10049699", "reactome": "R-BTA-444879", "name": "Relaxin receptor 2 binds relaxin 2 and INSL3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049687", "species_10049695" ], "products": [ "species_10049697" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020135", "O77801", "ENSBTAT00000027848", "O77801", "ENSBTAT00000027848", "E1BKC2", "ENSBTAT00000020135" ] }, "reaction_10049683": { "compartment": "compartment_984", "id": "reaction_10049683", "reactome": "R-BTA-444848", "name": "Relaxin 3 receptor 1 binds relaxin 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046333", "species_10046329" ], "products": [ "species_10046335" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055041", "F1MEV7", "ENSBTAT00000036249", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041" ] }, "reaction_10045292": { "compartment": "compartment_984", "id": "reaction_10045292", "reactome": "R-BTA-374251", "name": "DARC is a non-specific receptor for many chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045284", "species_10045288" ], "products": [ "species_10045290" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004179", "ENSBTAT00000026275", "P79255", "ENSBTAT00000026275", "F1N018", "ENSBTAT00000004179" ] }, "reaction_10045324": { "compartment": "compartment_984", "id": "reaction_10045324", "reactome": "R-BTA-374298", "name": "Opioid receptors bind opioid peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045302", "species_10045320" ], "products": [ "species_10045322" ], "modifiers": [], "additional_components": [ "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209" ] }, "reaction_10046735": { "compartment": "compartment_984", "id": "reaction_10046735", "reactome": "R-BTA-388560", "name": "Endothelin receptors bind endothelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045876", "species_10045886" ], "products": [ "species_10045888" ], "modifiers": [], "additional_components": [ "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571" ] }, "reaction_10046915": { "compartment": "compartment_984", "id": "reaction_10046915", "reactome": "R-BTA-388863", "name": "Neuropeptide Y receptors can bind neuropeptide Y-related peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046293", "species_10046275" ], "products": [ "species_10046295" ], "modifiers": [], "additional_components": [ "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "ENSBTAT00000062944", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149" ] }, "reaction_10046917": { "compartment": "compartment_984", "id": "reaction_10046917", "reactome": "R-BTA-388900", "name": "Neurotensin receptors can bind neurotensins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045950", "species_10045960" ], "products": [ "species_10045962" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006980", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980" ] }, "reaction_10049637": { "compartment": "compartment_984", "id": "reaction_10049637", "reactome": "R-BTA-444498", "name": "Thyrotropin-releasing hormone receptor binds thyrotropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046006", "species_10046002" ], "products": [ "species_10046018" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006982", "ENSBTAT00000026634", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982" ] }, "reaction_10046919": { "compartment": "compartment_984", "id": "reaction_10046919", "reactome": "R-BTA-388981", "name": "The Kiss receptor GPR54 binds kisspeptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045902", "species_10045898" ], "products": [ "species_10045904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028248", "ENSBTAT00000073562", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248" ] }, "reaction_10045350": { "compartment": "compartment_984", "id": "reaction_10045350", "reactome": "R-BTA-374337", "name": "Apelin receptor binds to apelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045346", "species_10045336" ], "products": [ "species_10045348" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039541", "ENSBTAT00000026630", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541" ] }, "reaction_10047864": { "compartment": "compartment_984", "id": "reaction_10047864", "reactome": "R-BTA-417890", "name": "P2Y5 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045826", "species_417891" ], "products": [ "species_10045828" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008730", "species_417891", "A6QL49", "ENSBTAT00000008730" ] }, "reaction_10047851": { "compartment": "compartment_984", "id": "reaction_10047851", "reactome": "R-BTA-417820", "name": "P2Y9 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045838", "species_417891" ], "products": [ "species_10045840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004269", "species_417891", "A4IFV1", "ENSBTAT00000004269" ] }, "reaction_10047866": { "compartment": "compartment_984", "id": "reaction_10047866", "reactome": "R-BTA-417896", "name": "P2Y6 receptor can bind to UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417888", "species_10045832" ], "products": [ "species_10045834" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057184", "F1MTB2", "ENSBTAT00000057184", "species_205687" ] }, "reaction_10047853": { "compartment": "compartment_984", "id": "reaction_10047853", "reactome": "R-BTA-417825", "name": "P2Y11 receptor can bind to ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114570", "species_10045976" ], "products": [ "species_10045978" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018000", "F1MU50", "ENSBTAT00000018000", "species_113592" ] }, "reaction_10047868": { "compartment": "compartment_984", "id": "reaction_10047868", "reactome": "R-BTA-417898", "name": "P2Y4 receptor can bind to UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046215", "species_417877" ], "products": [ "species_10046217" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054975", "species_29494", "F1MDW9", "ENSBTAT00000054975" ] }, "reaction_10090956": { "compartment": "compartment_984", "id": "reaction_10090956", "reactome": "R-BTA-9611277", "name": "P2RY12 antagonists bind P2RY12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611319", "species_10046221" ], "products": [ "species_10047855" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047870": { "compartment": "compartment_984", "id": "reaction_10047870", "reactome": "R-BTA-417908", "name": "P2RY1 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10045820" ], "products": [ "species_10045822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001919", "species_29370", "P48042", "ENSBTAT00000001919" ] }, "reaction_10047857": { "compartment": "compartment_984", "id": "reaction_10047857", "reactome": "R-BTA-417829", "name": "P2RY12 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10046221" ], "products": [ "species_10046223" ], "modifiers": [ [ "species_10047855", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047989": { "compartment": "compartment_984", "id": "reaction_10047989", "reactome": "R-BTA-418918", "name": "The UDP/CysLT (P2Y17) receptor can bind UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_417888" ], "products": [ "species_10045894" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_205687", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047860": { "compartment": "compartment_984", "id": "reaction_10047860", "reactome": "R-BTA-417842", "name": "P2Y10 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045844", "species_417891" ], "products": [ "species_10045846" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011278", "species_417891", "G3X6Q0", "ENSBTAT00000011278" ] }, "reaction_10047862": { "compartment": "compartment_984", "id": "reaction_10047862", "reactome": "R-BTA-417858", "name": "P2Y14 receptor can bind to UDP-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046227", "species_417855" ], "products": [ "species_10046229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027950", "species_29410", "Q3SX17", "ENSBTAT00000027950" ] }, "reaction_10047987": { "compartment": "compartment_984", "id": "reaction_10047987", "reactome": "R-BTA-418904", "name": "A1 and A3 receptors bind adenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046239", "species_83908" ], "products": [ "species_10046241" ], "modifiers": [], "additional_components": [ "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690" ] }, "reaction_10048003": { "compartment": "compartment_984", "id": "reaction_10048003", "reactome": "R-BTA-418925", "name": "ADORA2A,B bind Ade-Rib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047999", "species_83908" ], "products": [ "species_10048001" ], "modifiers": [], "additional_components": [ "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466" ] }, "reaction_10078536": { "compartment": "compartment_876", "id": "reaction_10078536", "reactome": "R-BTA-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_417891" ], "products": [ "species_109277", "species_6797635" ], "modifiers": [ [ "species_10078533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025329" ] }, "reaction_10048176": { "compartment": "compartment_984", "id": "reaction_10048176", "reactome": "R-BTA-419389", "name": "LPA-binding receptors bind LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045922", "species_417891" ], "products": [ "species_10045924" ], "modifiers": [], "additional_components": [ "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152" ] }, "reaction_10048180": { "compartment": "compartment_984", "id": "reaction_10048180", "reactome": "R-BTA-419428", "name": "S1PR2-5 bind S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_10046319" ], "products": [ "species_10046321" ], "modifiers": [], "additional_components": [ "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10049663": { "compartment": "compartment_984", "id": "reaction_10049663", "reactome": "R-BTA-444731", "name": "GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10046074" ], "products": [ "species_10046076" ], "modifiers": [], "additional_components": [ "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529" ] }, "reaction_10084702": { "compartment": "compartment_984", "id": "reaction_10084702", "reactome": "R-BTA-8862700", "name": "CMKLR1 binds Resolvin E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023982", "species_10084698" ], "products": [ "species_10084700" ], "modifiers": [], "additional_components": [ "CHEBI:81559", "species_9022660", "ENSBTAT00000029488", "B9VR26", "ENSBTAT00000029488", "CHEBI:81559", "species_9022660" ] }, "reaction_10051217": { "compartment": "compartment_984", "id": "reaction_10051217", "reactome": "R-BTA-517536", "name": "N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_517533", "species_10046339" ], "products": [ "species_10046341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007469", "Q3T0E9", "ENSBTAT00000007469", "species_517533" ] }, "reaction_10048178": { "compartment": "compartment_984", "id": "reaction_10048178", "reactome": "R-BTA-419426", "name": "Cannabinoid receptors can bind cannabinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444560", "species_10046255" ], "products": [ "species_10046257" ], "modifiers": [], "additional_components": [ "species_5693754", "species_426030", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030" ] }, "reaction_10053333": { "compartment": "compartment_984", "id": "reaction_10053333", "reactome": "R-BTA-964773", "name": "OXGR1 binds 2OG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_561075", "species_10046447" ], "products": [ "species_10046449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035454", "F1MYN3", "ENSBTAT00000035454", "species_113594" ] }, "reaction_10067350": { "compartment": "compartment_876", "id": "reaction_10067350", "reactome": "R-BTA-3296244", "name": "SUCNR1 binds SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433123", "species_10046441" ], "products": [ "species_10046443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068791", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536" ] }, "reaction_10049641": { "compartment": "compartment_984", "id": "reaction_10049641", "reactome": "R-BTA-444572", "name": "Zinc is an agonist of GPR39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046134", "species_158417" ], "products": [ "species_10046136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065884", "species_29426", "G3MWJ9", "ENSBTAT00000065884" ] }, "reaction_10048172": { "compartment": "compartment_984", "id": "reaction_10048172", "reactome": "R-BTA-419334", "name": "Melatonin receptors can bind melatonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419339", "species_10046269" ], "products": [ "species_10046271" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068939", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339" ] }, "reaction_10081580": { "compartment": "compartment_984", "id": "reaction_10081580", "reactome": "R-BTA-6805205", "name": "GPR35 binds kynurenic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6805204", "species_10081576" ], "products": [ "species_10081578" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021281", "F1N600", "ENSBTAT00000021281", "species_6805204" ] }, "reaction_10067362": { "compartment": "compartment_876", "id": "reaction_10067362", "reactome": "R-BTA-3296309", "name": "HCAR3 binds HCAR3 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296330", "species_10046463" ], "products": [ "species_10046465" ], "modifiers": [], "additional_components": [ "CHEBI:37098", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:37098", "species_197230" ] }, "reaction_10067364": { "compartment": "compartment_876", "id": "reaction_10067364", "reactome": "R-BTA-3296326", "name": "HCAR1 binds LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046453", "species_373863" ], "products": [ "species_10046455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001202", "species_373863", "B9UM28", "ENSBTAT00000001202" ] }, "reaction_10048174": { "compartment": "compartment_984", "id": "reaction_10048174", "reactome": "R-BTA-419351", "name": "PAF receptor binds platelet activating factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419375", "species_10045996" ], "products": [ "species_10045998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038757", "Q9TTY5", "ENSBTAT00000038757", "species_419375" ] }, "reaction_10083937": { "compartment": "compartment_984", "id": "reaction_10083937", "reactome": "R-BTA-8851679", "name": "GPR183 binds 7alpha,25-dihydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851675", "species_10046483" ], "products": [ "species_10046485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007471", "Q1RMI1", "ENSBTAT00000007471", "species_192184" ] }, "reaction_10049643": { "compartment": "compartment_984", "id": "reaction_10049643", "reactome": "R-BTA-444606", "name": "T1R2/T1R3 dimer is a sweet taste receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046501", "species_444679" ], "products": [ "species_10046503" ], "modifiers": [], "additional_components": [ "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207" ] }, "reaction_10045138": { "compartment": "compartment_984", "id": "reaction_10045138", "reactome": "R-BTA-373075", "name": "Metabotropic glutamate receptors bind glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10045134" ], "products": [ "species_10045136" ], "modifiers": [], "additional_components": [ "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "species_210382" ] }, "reaction_10067348": { "compartment": "compartment_876", "id": "reaction_10067348", "reactome": "R-BTA-3296233", "name": "T2Rs bind bitter-tasting compounds", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046435", "species_3296423" ], "products": [ "species_10046437" ], "modifiers": [], "additional_components": [ "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537" ] }, "reaction_10089211": { "compartment": "compartment_876", "id": "reaction_10089211", "reactome": "R-BTA-8982019", "name": "Active G alpha (i)i1/i2/i3 binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039640", "species_10089193" ], "products": [ "species_10089209" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089197": { "compartment": "compartment_876", "id": "reaction_10089197", "reactome": "R-BTA-8982012", "name": "G alpha (i):RGS dissociates to inactive G alpha (i)i1/i2/i3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089195" ], "products": [ "species_10039660", "species_10089193" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10088940": { "compartment": "compartment_876", "id": "reaction_10088940", "reactome": "R-BTA-8964242", "name": "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088932", "species_113592" ], "products": [ "species_29370", "species_10088937" ], "modifiers": [ [ "species_10088932", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088942": { "compartment": "compartment_70101", "id": "reaction_10088942", "reactome": "R-BTA-8964329", "name": "G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088937" ], "products": [ "species_10088935", "species_10039640" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089214": { "compartment": "compartment_876", "id": "reaction_10089214", "reactome": "R-BTA-8982020", "name": "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089209" ], "products": [ "species_29372", "species_10089195" ], "modifiers": [ [ "species_10089209", "catalyst" ] ], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10048370": { "compartment": "compartment_70101", "id": "reaction_10048370", "reactome": "R-BTA-420883", "name": "Opsins act as GEFs for G alpha-t", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10048361" ], "products": [ "species_29420", "species_10048367" ], "modifiers": [ [ "species_10048206", "catalyst" ] ], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "P63212", "ENSBTAT00000003959", "species_29420", "P04695", "ENSBTAT00000023990", "P04695", "ENSBTAT00000023990", "species_29438", "P63212", "ENSBTAT00000003959", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10037037": { "compartment": "compartment_70101", "id": "reaction_10037037", "reactome": "R-BTA-111962", "name": "PDE4A,C,D hydrolyse cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037034", "catalyst" ] ], "additional_components": [ "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100" ] }, "reaction_10039658": { "compartment": "compartment_876", "id": "reaction_10039658", "reactome": "R-BTA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10036997" ], "products": [ "species_10039655" ], "modifiers": [ [ "species_10036997", "catalyst" ] ], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10039674": { "compartment": "compartment_876", "id": "reaction_10039674", "reactome": "R-BTA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039655" ], "products": [ "species_29372", "species_10039669" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039667": { "compartment": "compartment_876", "id": "reaction_10039667", "reactome": "R-BTA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039671": { "compartment": "compartment_876", "id": "reaction_10039671", "reactome": "R-BTA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039669" ], "products": [ "species_10036997", "species_10039646" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420" ] }, "reaction_10036959": { "compartment": "compartment_70101", "id": "reaction_10036959", "reactome": "R-BTA-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10037045": { "compartment": "compartment_70101", "id": "reaction_10037045", "reactome": "R-BTA-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036956" ], "products": [ "species_29372", "species_10037043", "species_10036942" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "ENSBTAT00000074229" ] }, "reaction_10039676": { "compartment": "compartment_876", "id": "reaction_10039676", "reactome": "R-BTA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039662" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039664": { "compartment": "compartment_876", "id": "reaction_10039664", "reactome": "R-BTA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039662" ], "products": [ "species_10036997", "species_10039646", "species_10039660" ], "modifiers": [], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10039651": { "compartment": "compartment_876", "id": "reaction_10039651", "reactome": "R-BTA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039648" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039653": { "compartment": "compartment_876", "id": "reaction_10039653", "reactome": "R-BTA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10039642" ], "products": [ "species_10039644" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10046534": { "compartment": "compartment_947587", "id": "reaction_10046534", "reactome": "R-BTA-380073", "name": "Liganded Gi-activating GPCR acts as a GEF for Gi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046509" ], "products": [ "species_29420", "species_10046513" ], "modifiers": [ [ "species_10046509", "catalyst" ], [ "species_10046532", "inhibitor" ] ], "additional_components": [ "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "A0A3Q1MMQ2", "ENSBTAT00000081300", "A0A3Q1MKT3", "ENSBTAT00000078547" ] }, "reaction_10089224": { "compartment": "compartment_876", "id": "reaction_10089224", "reactome": "R-BTA-8982026", "name": "G alpha (q):RGS dissociates to inactive G alpha (q)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089219" ], "products": [ "species_10089199", "species_10037355" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420" ] }, "reaction_10047979": { "compartment": "compartment_876", "id": "reaction_10047979", "reactome": "R-BTA-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954" ], "products": [ "species_10037355" ], "modifiers": [ [ "species_10036954", "catalyst" ], [ "species_10047977", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "F1N7R3", "ENSBTAT00000005904" ] }, "reaction_10048632": { "compartment": "compartment_876", "id": "reaction_10048632", "reactome": "R-BTA-426209", "name": "DAG activation of TRPC channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048628", "species_114519" ], "products": [ "species_10048630" ], "modifiers": [], "additional_components": [ "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10048543": { "compartment": "compartment_70101", "id": "reaction_10048543", "reactome": "R-BTA-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519", "species_10048539" ], "products": [ "species_10048541" ], "modifiers": [], "additional_components": [ "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "species_6797635" ] }, "reaction_10048587": { "compartment": "compartment_70101", "id": "reaction_10048587", "reactome": "R-BTA-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426030" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10048584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073448" ] }, "reaction_10048580": { "compartment": "compartment_876", "id": "reaction_10048580", "reactome": "R-BTA-426032", "name": "DAG is metabolized by DAGL to 2-AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519" ], "products": [ "species_426026", "species_426030" ], "modifiers": [ [ "species_10048577", "catalyst" ] ], "additional_components": [ "E1BBV2", "ENSBTAT00000018523", "F6RA94", "ENSBTAT00000012173" ] }, "reaction_10076743": { "compartment": "compartment_876", "id": "reaction_10076743", "reactome": "R-BTA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10076740", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022100" ] }, "reaction_10048660": { "compartment": "compartment_70101", "id": "reaction_10048660", "reactome": "R-BTA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10048657", "catalyst" ] ], "additional_components": [ "F1MCG9", "ENSBTAT00000031198", "A0A3Q1NJA6", "ENSBTAT00000066461", "E1BGA9", "ENSBTAT00000022905", "A0A3Q1LYT4", "ENSBTAT00000075621", "A0A3Q1N4W0", "ENSBTAT00000080144" ] }, "reaction_10037549": { "compartment": "compartment_876", "id": "reaction_10037549", "reactome": "R-BTA-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037544" ], "products": [ "species_10037546" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "species_6810412", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "species_6797635", "species_114520", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10047823": { "compartment": "compartment_70101", "id": "reaction_10047823", "reactome": "R-BTA-400586", "name": "G alpha (q) binds to Trio family RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954", "species_10047819" ], "products": [ "species_10047821" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10064910": { "compartment": "compartment_984", "id": "reaction_10064910", "reactome": "R-BTA-2179387", "name": "Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040221", "species_10040201" ], "products": [ "species_10064908" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10064915": { "compartment": "compartment_70101", "id": "reaction_10064915", "reactome": "R-BTA-2179407", "name": "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10064912", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10064919": { "compartment": "compartment_70101", "id": "reaction_10064919", "reactome": "R-BTA-2179415", "name": "GRB2:SOS1 binds to HBEGF:p-Y-EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10064908" ], "products": [ "species_10064912" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10089203": { "compartment": "compartment_876", "id": "reaction_10089203", "reactome": "R-BTA-8982017", "name": "Active G alpha (q) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089199", "species_10036954" ], "products": [ "species_10089201" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10046149": { "compartment": "compartment_70101", "id": "reaction_10046149", "reactome": "R-BTA-379048", "name": "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046140" ], "products": [ "species_29420", "species_10046142" ], "modifiers": [ [ "species_10046146", "catalyst" ] ], "additional_components": [ "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "species_266013", "A7MBH4", "ENSBTAT00000023275", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10089222": { "compartment": "compartment_876", "id": "reaction_10089222", "reactome": "R-BTA-8982025", "name": "G alpha (q) in G (q):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089201" ], "products": [ "species_29372", "species_10089219" ], "modifiers": [ [ "species_10089201", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10047947": { "compartment": "compartment_70101", "id": "reaction_10047947", "reactome": "R-BTA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10047944", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100", "A0A3Q1M3R2", "ENSBTAT00000085287", "A0A3Q1M5L1", "ENSBTAT00000082666" ] }, "reaction_10089226": { "compartment": "compartment_876", "id": "reaction_10089226", "reactome": "R-BTA-8982641", "name": "ADRB2:GRK complex dissociates to Phosphorylated ADRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083948" ], "products": [ "species_10083941", "species_10084012" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789" ] }, "reaction_10089228": { "compartment": "compartment_876", "id": "reaction_10089228", "reactome": "R-BTA-8982645", "name": "GRKs bind ADRB2:Catecholamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083941", "species_10051595" ], "products": [ "species_10083943" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10091247": { "compartment": "compartment_70101", "id": "reaction_10091247", "reactome": "R-BTA-9629675", "name": "PDE3A hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10091244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072849" ] }, "reaction_10083951": { "compartment": "compartment_876", "id": "reaction_10083951", "reactome": "R-BTA-8851797", "name": "ADRB2 in ADRB2:GRK complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083943", "species_113592" ], "products": [ "species_29370", "species_10083948" ], "modifiers": [ [ "species_10083943", "catalyst" ] ], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10084016": { "compartment": "compartment_70101", "id": "reaction_10084016", "reactome": "R-BTA-8852167", "name": "ADRB2:Catecholamine binds ARRB1, ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10084012" ], "products": [ "species_10084014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092055": { "compartment": "compartment_70101", "id": "reaction_10092055", "reactome": "R-BTA-9705507", "name": "PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10092052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10047498": { "compartment": "compartment_70101", "id": "reaction_10047498", "reactome": "R-BTA-392300", "name": "G beta:gamma activated PI3Kgamma converts PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047495", "catalyst" ] ], "additional_components": [ "P63212", "ENSBTAT00000003959", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10043315": { "compartment": "compartment_876", "id": "reaction_10043315", "reactome": "R-BTA-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10037311" ], "products": [ "species_10043313" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005600", "P61585", "ENSBTAT00000005600", "species_179838" ] }, "reaction_10088962": { "compartment": "compartment_70101", "id": "reaction_10088962", "reactome": "R-BTA-8964619", "name": "PAK1 binds ARHGEF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047596", "species_10048105" ], "products": [ "species_10088960" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080749", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10051656": { "compartment": "compartment_70101", "id": "reaction_10051656", "reactome": "R-BTA-749453", "name": "Liganded Gz-activating GPCR acts as a GEF for Gz", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051649" ], "products": [ "species_29420", "species_10051653" ], "modifiers": [ [ "species_10051649", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959" ] }, "reaction_10047468": { "compartment": "compartment_876", "id": "reaction_10047468", "reactome": "R-BTA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036997", "species_10047464" ], "products": [ "species_10047466" ], "modifiers": [], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10089167": { "compartment": "compartment_876", "id": "reaction_10089167", "reactome": "R-BTA-8981892", "name": "Active G alpha (z) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089163", "species_10047464" ], "products": [ "species_10089165" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089217": { "compartment": "compartment_876", "id": "reaction_10089217", "reactome": "R-BTA-8982021", "name": "G alpha (z) in G alpha (z):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089165" ], "products": [ "species_29372", "species_10089205" ], "modifiers": [ [ "species_10089165", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089207": { "compartment": "compartment_876", "id": "reaction_10089207", "reactome": "R-BTA-8982018", "name": "G alpha (z):RGS complex dissociates to give inactive G alpha (z)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089205" ], "products": [ "species_10051645", "species_10089163" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10048170": { "compartment": "compartment_70101", "id": "reaction_10048170", "reactome": "R-BTA-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047839" ], "products": [ "species_29420", "species_10047841" ], "modifiers": [ [ "species_10048167", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "E1B9G8", "ENSBTAT00000014311", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1M8D9", "ENSBTAT00000071999", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LQ45", "ENSBTAT00000078928", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1MA97", "ENSBTAT00000081198", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1LXW7", "ENSBTAT00000081961", "A0A3Q1MA22", "ENSBTAT00000069238", "Q08DA6", "ENSBTAT00000011773", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417", "F1N7C3", "ENSBTAT00000015471", "A0A3Q1MA88", "ENSBTAT00000069507", "Q58CS5", "ENSBTAT00000009131", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1N5H1", "ENSBTAT00000068004" ] }, "reaction_10047552": { "compartment": "compartment_70101", "id": "reaction_10047552", "reactome": "R-BTA-398184", "name": "LARG activation by G alpha 12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047548", "species_10047544" ], "products": [ "species_10047550" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081099", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "A0A3Q1MN47", "ENSBTAT00000081099" ] }, "reaction_10051667": { "compartment": "compartment_70101", "id": "reaction_10051667", "reactome": "R-BTA-751029", "name": "Liganded G12/13-activating GPCR acts as a GEF for G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051664" ], "products": [ "species_29420", "species_10051660" ], "modifiers": [ [ "species_10051664", "catalyst" ] ], "additional_components": [ "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10037330": { "compartment": "compartment_70101", "id": "reaction_10037330", "reactome": "R-BTA-114544", "name": "p115-RhoGEF activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10037327", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10037332": { "compartment": "compartment_70101", "id": "reaction_10037332", "reactome": "R-BTA-114548", "name": "G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037325", "species_10037321" ], "products": [ "species_10037327" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066417", "G5E6P3", "ENSBTAT00000062941", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10047956": { "compartment": "compartment_876", "id": "reaction_10047956", "reactome": "R-BTA-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047544" ], "products": [ "species_10047953" ], "modifiers": [ [ "species_10047544", "catalyst" ] ], "additional_components": [ "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "species_29420", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757" ] }, "reaction_10072123": { "compartment": "compartment_5263228", "id": "reaction_10072123", "reactome": "R-BTA-5610733", "name": "KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072119", "species_10072115" ], "products": [ "species_10072121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075908", "species_29438", "species_29420", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908" ] }, "reaction_10072154": { "compartment": "compartment_24337", "id": "reaction_10072154", "reactome": "R-BTA-5610763", "name": "PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072144" ], "products": [ "species_10072148" ], "modifiers": [ [ "species_10072152", "inhibitor" ] ], "additional_components": [ "E1BE57", "ENSBTAT00000017670", "E1BE57", "ENSBTAT00000017670", "ENSBTAT00000064817" ] }, "reaction_10072220": { "compartment": "compartment_5263228", "id": "reaction_10072220", "reactome": "R-BTA-5610767", "name": "The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072218", "catalyst" ], [ "species_10072121", "catalyst" ], [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BKE3", "ENSBTAT00000035821", "A0A3Q1MNB3", "ENSBTAT00000078675", "Q32KR5", "ENSBTAT00000087155", "A0A452DIR3", "ENSBTAT00000007606", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308" ] }, "reaction_10072081": { "compartment": "compartment_70101", "id": "reaction_10072081", "reactome": "R-BTA-5610723", "name": "GLI proteins bind SUFU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072077", "species_10072073" ], "products": [ "species_10072079" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810" ] }, "reaction_10072138": { "compartment": "compartment_5263232", "id": "reaction_10072138", "reactome": "R-BTA-5610742", "name": "SCF(beta-TrCP) ubiquitinates p-GLI1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072130", "species_10033408" ], "products": [ "species_10072135" ], "modifiers": [ [ "species_10043873", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10072199": { "compartment": "compartment_5263232", "id": "reaction_10072199", "reactome": "R-BTA-5610766", "name": "The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072165" ], "products": [ "species_10072173" ], "modifiers": [ [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ], [ "species_10072187", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308", "ENSBTAT00000036487" ] }, "reaction_10072713": { "compartment": "compartment_7660", "id": "reaction_10072713", "reactome": "R-BTA-5635856", "name": "SPOP:CUL3:RBX1 ubiquitinates GLI2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072710", "species_10036828" ], "products": [ "species_10072708" ], "modifiers": [ [ "species_10072710", "catalyst" ] ], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660" ] }, "reaction_10072715": { "compartment": "compartment_5263228", "id": "reaction_10072715", "reactome": "R-BTA-5635860", "name": "GLI:SUFU translocates to the ciliary tip in response to Hh signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072119", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "ENSBTAT00000075908" ] }, "reaction_10072685": { "compartment": "compartment_7660", "id": "reaction_10072685", "reactome": "R-BTA-5635845", "name": "GLI proteins bind CDC73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072669", "species_10072681" ], "products": [ "species_10072683" ], "modifiers": [], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "ENSBTAT00000022205", "E1BPQ8", "ENSBTAT00000022205", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10072606": { "compartment": "compartment_261122", "id": "reaction_10072606", "reactome": "R-BTA-5632677", "name": "PTCH is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072602" ], "products": [ "species_10072604" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064817", "ENSBTAT00000064817" ] }, "reaction_10072720": { "compartment": "compartment_261122", "id": "reaction_10072720", "reactome": "R-BTA-5635865", "name": "SMURF1/2 dissociates from ub-PTCH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072718" ], "products": [ "species_10042973", "species_10072602" ], "modifiers": [], "additional_components": [ "G3N1D5", "ENSBTAT00000064817", "F1MLS5", "ENSBTAT00000043725", "ENSBTAT00000043725", "ENSBTAT00000064817" ] }, "reaction_10072677": { "compartment": "compartment_5263228", "id": "reaction_10072677", "reactome": "R-BTA-5635843", "name": "GLI translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072675" ], "products": [ "species_10072663" ], "modifiers": [], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10074038": { "compartment": "compartment_876", "id": "reaction_10074038", "reactome": "R-BTA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BG59", "ENSBTAT00000029159", "A0A3Q1MPT9", "ENSBTAT00000086336", "A0A3Q1MD11", "ENSBTAT00000081804", "A0A3Q1M7J4", "ENSBTAT00000085129", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A452DJB1", "ENSBTAT00000044847", "A0A452DHX3", "ENSBTAT00000003498", "F1N5N3", "ENSBTAT00000021391", "F1MP52", "ENSBTAT00000015112", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LSU3", "ENSBTAT00000068365", "species_6797635", "A0A3Q1N010", "ENSBTAT00000084300" ] }, "reaction_10091515": { "compartment": "compartment_876", "id": "reaction_10091515", "reactome": "R-BTA-9647994", "name": "RAS proteins are depalmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039726" ], "products": [ "species_8848337", "species_10091512" ], "modifiers": [ [ "species_10091502", "catalyst" ], [ "species_10091504", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091458": { "compartment": "compartment_12045", "id": "reaction_10091458", "reactome": "R-BTA-9647977", "name": "ICMT methylates S-Farn RAS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10091448" ], "products": [ "species_10091454", "species_71285" ], "modifiers": [ [ "species_10077880", "catalyst" ], [ "species_10091456", "inhibitor" ] ], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29426", "G3N1V4", "ENSBTAT00000064297", "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10091490": { "compartment": "compartment_20699", "id": "reaction_10091490", "reactome": "R-BTA-9647982", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091454", "species_200993" ], "products": [ "species_10091477", "species_76194" ], "modifiers": [ [ "species_10091487", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "Q5EA55", "ENSBTAT00000069302", "Q58DA8", "ENSBTAT00000075844" ] }, "reaction_10091506": { "compartment": "compartment_876", "id": "reaction_10091506", "reactome": "R-BTA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10091502" ], "products": [ "species_10091504" ], "modifiers": [], "additional_components": [ "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091479": { "compartment": "compartment_876", "id": "reaction_10091479", "reactome": "R-BTA-9647980", "name": "mature RAS proteins translocate to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091477" ], "products": [ "species_10039726" ], "modifiers": [], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897" ] }, "reaction_10091527": { "compartment": "compartment_876", "id": "reaction_10091527", "reactome": "R-BTA-9649733", "name": "mature p21 RAS binds GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10039726" ], "products": [ "species_10040312" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10074088": { "compartment": "compartment_876", "id": "reaction_10074088", "reactome": "R-BTA-5672969", "name": "Phosphorylation of RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074042" ], "products": [ "species_29370", "species_10074065" ], "modifiers": [ [ "species_10074085", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073930": { "compartment": "compartment_70101", "id": "reaction_10073930", "reactome": "R-BTA-5672957", "name": "PP2A dephosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073919" ], "products": [ "species_10073927", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073917": { "compartment": "compartment_70101", "id": "reaction_10073917", "reactome": "R-BTA-5672951", "name": "Inactive RAFs bind YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073913" ], "products": [ "species_10073915" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073932": { "compartment": "compartment_70101", "id": "reaction_10073932", "reactome": "R-BTA-5672958", "name": "YWHAB dimer dissociates from KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073927" ], "products": [ "species_10037668", "species_10073925" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091548": { "compartment": "compartment_876", "id": "reaction_10091548", "reactome": "R-BTA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657579", "species_10074042" ], "products": [ "species_10074135" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10073921": { "compartment": "compartment_70101", "id": "reaction_10073921", "reactome": "R-BTA-5672954", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073869" ], "products": [ "species_10073919" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073904": { "compartment": "compartment_876", "id": "reaction_10073904", "reactome": "R-BTA-5672950", "name": "\"Activator\" RAF:YWHAB dimer binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10073896" ], "products": [ "species_10073898" ], "modifiers": [ [ "species_10073902", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000070853" ] }, "reaction_10073872": { "compartment": "compartment_70101", "id": "reaction_10073872", "reactome": "R-BTA-5672948", "name": "MARK3 phosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_113592" ], "products": [ "species_29370", "species_10073869" ], "modifiers": [ [ "species_10073863", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074050": { "compartment": "compartment_876", "id": "reaction_10074050", "reactome": "R-BTA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073898", "species_10074040" ], "products": [ "species_10074042" ], "modifiers": [ [ "species_10074048", "inhibitor" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10073940": { "compartment": "compartment_70101", "id": "reaction_10073940", "reactome": "R-BTA-5672960", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073938" ], "products": [ "species_10037668", "species_10073936" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073942": { "compartment": "compartment_70101", "id": "reaction_10073942", "reactome": "R-BTA-5672961", "name": "PP2A dephosphorylates inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073915" ], "products": [ "species_29372", "species_10073938" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10074184": { "compartment": "compartment_20699", "id": "reaction_10074184", "reactome": "R-BTA-5674140", "name": "PAQR3 binds inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074180", "species_10073913" ], "products": [ "species_10074182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071243", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1M5M4", "ENSBTAT00000071243" ] }, "reaction_10074221": { "compartment": "compartment_876", "id": "reaction_10074221", "reactome": "R-BTA-5675417", "name": "PEBP1 binds activated RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074213", "species_10074217" ], "products": [ "species_10074219" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000024107", "P13696", "ENSBTAT00000024107", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10074156": { "compartment": "compartment_876", "id": "reaction_10074156", "reactome": "R-BTA-5674022", "name": "BRAP autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10074144" ], "products": [ "species_10074153" ], "modifiers": [ [ "species_10074144", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074238": { "compartment": "compartment_876", "id": "reaction_10074238", "reactome": "R-BTA-5675433", "name": "PP5 dephosphorylates RAF1 S338", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074213" ], "products": [ "species_29372", "species_10074225" ], "modifiers": [ [ "species_10074235", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000010538" ] }, "reaction_10074146": { "compartment": "compartment_876", "id": "reaction_10074146", "reactome": "R-BTA-5674018", "name": "BRAP binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10074046" ], "products": [ "species_10074144" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074148": { "compartment": "compartment_70101", "id": "reaction_10074148", "reactome": "R-BTA-5674019", "name": "BRAP binds KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_10074046" ], "products": [ "species_10074048" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074231": { "compartment": "compartment_876", "id": "reaction_10074231", "reactome": "R-BTA-5675431", "name": "PP2A dephosphorylates RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074225" ], "products": [ "species_10074229", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10091534": { "compartment": "compartment_876", "id": "reaction_10091534", "reactome": "R-BTA-9649736", "name": "RAS intrinsic GTPase activity hydrolyzes GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728" ], "products": [ "species_10040312" ], "modifiers": [ [ "species_10039728", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091580": { "compartment": "compartment_876", "id": "reaction_10091580", "reactome": "R-BTA-9658253", "name": "RAS:GTP binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10039728" ], "products": [ "species_10091578" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10074137": { "compartment": "compartment_876", "id": "reaction_10074137", "reactome": "R-BTA-5672978", "name": "RAF phosphorylates MAP2K dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074123" ], "products": [ "species_10074114", "species_29370" ], "modifiers": [ [ "species_10074123", "catalyst" ], [ "species_10074125", "inhibitor" ], [ "species_10074135", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091576": { "compartment": "compartment_876", "id": "reaction_10091576", "reactome": "R-BTA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074118", "species_9657577" ], "products": [ "species_10091574" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074129": { "compartment": "compartment_876", "id": "reaction_10074129", "reactome": "R-BTA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_113592" ], "products": [ "species_10074118", "species_29370" ], "modifiers": [ [ "species_10074114", "catalyst" ], [ "species_10074127", "inhibitor" ], [ "species_10074121", "inhibitor" ], [ "species_10074125", "inhibitor" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091568": { "compartment": "compartment_876", "id": "reaction_10091568", "reactome": "R-BTA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657567", "species_10074123" ], "products": [ "species_10074125" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074176": { "compartment": "compartment_74700", "id": "reaction_10074176", "reactome": "R-BTA-5674130", "name": "MAP2Ks and MAPKs are phosphorylated at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074172" ], "products": [ "species_29370", "species_10074174" ], "modifiers": [], "additional_components": [ "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833" ] }, "reaction_10074195": { "compartment": "compartment_20699", "id": "reaction_10074195", "reactome": "R-BTA-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074190" ], "products": [ "species_29370", "species_10074192" ], "modifiers": [ [ "species_10074190", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984" ] }, "reaction_10091570": { "compartment": "compartment_876", "id": "reaction_10091570", "reactome": "R-BTA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657570" ], "products": [ "species_10074127" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091572": { "compartment": "compartment_876", "id": "reaction_10091572", "reactome": "R-BTA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657574" ], "products": [ "species_10074121" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091595": { "compartment": "compartment_876", "id": "reaction_10091595", "reactome": "R-BTA-9660557", "name": "RAS:GTP binds RAL GDS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091591", "species_10091589" ], "products": [ "species_10091593" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10091529": { "compartment": "compartment_876", "id": "reaction_10091529", "reactome": "R-BTA-9649735", "name": "Intrinsic nucleotide exchange on RAS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10075256": { "compartment": "compartment_7660", "id": "reaction_10075256", "reactome": "R-BTA-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075220" ], "products": [ "species_10075236", "species_10075202" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075260": { "compartment": "compartment_7660", "id": "reaction_10075260", "reactome": "R-BTA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075208" ], "products": [ "species_10075258" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000012303" ] }, "reaction_10075262": { "compartment": "compartment_70101", "id": "reaction_10075262", "reactome": "R-BTA-5687126", "name": "p-S215 FOXO3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075234" ], "products": [ "species_10075226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10075251": { "compartment": "compartment_70101", "id": "reaction_10075251", "reactome": "R-BTA-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075241" ], "products": [ "species_10075249" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075218": { "compartment": "compartment_7660", "id": "reaction_10075218", "reactome": "R-BTA-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066851", "species_10075214" ], "products": [ "species_10075216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075253": { "compartment": "compartment_7660", "id": "reaction_10075253", "reactome": "R-BTA-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075249" ], "products": [ "species_10075241" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "ENSBTAT00000017629" ] }, "reaction_10075223": { "compartment": "compartment_7660", "id": "reaction_10075223", "reactome": "R-BTA-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075216" ], "products": [ "species_113582", "species_10075220" ], "modifiers": [ [ "species_10075216", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075916": { "compartment": "compartment_70101", "id": "reaction_10075916", "reactome": "R-BTA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075904" ], "products": [ "species_29370", "species_10075913" ], "modifiers": [ [ "species_10075904", "catalyst" ] ], "additional_components": [ "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303", "F1MH23", "ENSBTAT00000012303", "Q3MI00", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10076193": { "compartment": "compartment_7660", "id": "reaction_10076193", "reactome": "R-BTA-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076189", "species_10076185" ], "products": [ "species_10076191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075652", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10075906": { "compartment": "compartment_70101", "id": "reaction_10075906", "reactome": "R-BTA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075236", "species_10067944" ], "products": [ "species_10075904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075205": { "compartment": "compartment_70101", "id": "reaction_10075205", "reactome": "R-BTA-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075194" ], "products": [ "species_10075202", "species_29370" ], "modifiers": [ [ "species_10047654", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10076229": { "compartment": "compartment_7660", "id": "reaction_10076229", "reactome": "R-BTA-5692779", "name": "p-S182 MAPKAPK5 phosphorylates FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10042661" ], "products": [ "species_113582", "species_10076226" ], "modifiers": [ [ "species_10066865", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127", "ENSBTAT00000012303" ] }, "reaction_10075239": { "compartment": "compartment_70101", "id": "reaction_10075239", "reactome": "R-BTA-5687101", "name": "p-T182 MAPKAPK5 phosphorylates FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075232" ], "products": [ "species_10075234", "species_29370" ], "modifiers": [ [ "species_10075236", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "ENSBTAT00000012303" ] }, "reaction_10076198": { "compartment": "compartment_7660", "id": "reaction_10076198", "reactome": "R-BTA-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076191" ], "products": [ "species_113550", "species_10076195" ], "modifiers": [ [ "species_10076191", "catalyst" ] ], "additional_components": [ "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652", "A0A3Q1MTC5", "ENSBTAT00000075652", "G5E577", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10039690": { "compartment": "compartment_74700", "id": "reaction_10039690", "reactome": "R-BTA-170964", "name": "FRS2 binds to active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039686", "species_10039684" ], "products": [ "species_10039688" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090954": { "compartment": "compartment_74700", "id": "reaction_10090954", "reactome": "R-BTA-9610163", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090951", "species_113592" ], "products": [ "species_10090933", "species_29370" ], "modifiers": [ [ "species_10090951", "catalyst" ] ], "additional_components": [ "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039711": { "compartment": "compartment_74700", "id": "reaction_10039711", "reactome": "R-BTA-170978", "name": "p-FRS2:CRKL binds C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039703", "species_10039707" ], "products": [ "species_10039709" ], "modifiers": [], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039697": { "compartment": "compartment_74700", "id": "reaction_10039697", "reactome": "R-BTA-170977", "name": "FRS2 is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039688" ], "products": [ "species_29370", "species_10039694" ], "modifiers": [ [ "species_10039688", "catalyst" ] ], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090944": { "compartment": "compartment_74700", "id": "reaction_10090944", "reactome": "R-BTA-9610153", "name": "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090935", "species_113592" ], "products": [ "species_29370", "species_10090937" ], "modifiers": [ [ "species_10090935", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10090949": { "compartment": "compartment_70101", "id": "reaction_10090949", "reactome": "R-BTA-9610156", "name": "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090937" ], "products": [ "species_10090946", "species_29370" ], "modifiers": [ [ "species_10090937", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039592": { "compartment": "compartment_876", "id": "reaction_10039592", "reactome": "R-BTA-169904", "name": "C3G stimulates nucleotide exchange on Rap1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039587" ], "products": [ "species_10039589", "species_29420" ], "modifiers": [ [ "species_10039579", "catalyst" ] ], "additional_components": [ "P62833", "ENSBTAT00000068678", "species_29420", "P62833", "ENSBTAT00000068678", "species_29438", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039581": { "compartment": "compartment_984", "id": "reaction_10039581", "reactome": "R-BTA-169895", "name": "Crk's SH3 domain engages C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039579" ], "products": [ "species_10039579" ], "modifiers": [], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039601": { "compartment": "compartment_876", "id": "reaction_10039601", "reactome": "R-BTA-169905", "name": "ARMS is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039598" ], "products": [ "species_29370", "species_10039579" ], "modifiers": [ [ "species_10039598", "catalyst" ] ], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10074879": { "compartment": "compartment_70101", "id": "reaction_10074879", "reactome": "R-BTA-5685366", "name": "GRB2-1:SOS1 binds p-Y-SHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073958", "species_10035491" ], "products": [ "species_10073960" ], "modifiers": [], "additional_components": [ "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112" ] }, "reaction_10039736": { "compartment": "compartment_876", "id": "reaction_10039736", "reactome": "R-BTA-170986", "name": "Ral-GDS binds to Ras-GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039732", "species_10039728" ], "products": [ "species_10039734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1M6Z6", "ENSBTAT00000087412" ] }, "reaction_10040570": { "compartment": "compartment_70101", "id": "reaction_10040570", "reactome": "R-BTA-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040546", "species_113592" ], "products": [ "species_10040551", "species_29370" ], "modifiers": [ [ "species_10040567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084476", "ENSBTAT00000084476", "species_29926", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10090994": { "compartment": "compartment_7660", "id": "reaction_10090994", "reactome": "R-BTA-9613213", "name": "NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090982", "species_10090978", "species_10090990" ], "products": [ "species_10090992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008295", "ENSBTAT00000019612", "G3N0C9", "ENSBTAT00000064240", "G3N0C9", "ENSBTAT00000064240", "F1N3F6", "ENSBTAT00000019612", "Q1RMU0", "ENSBTAT00000008295" ] }, "reaction_10041851": { "compartment": "compartment_947587", "id": "reaction_10041851", "reactome": "R-BTA-198266", "name": "PI3K produces PIP3 and other phosphatidyl inositides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10041848", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10041869": { "compartment": "compartment_947587", "id": "reaction_10041869", "reactome": "R-BTA-198315", "name": "Active IRS recruits PI3K to the plasma membrane and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10041865" ], "products": [ "species_10041867" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10041917": { "compartment": "compartment_7660", "id": "reaction_10041917", "reactome": "R-BTA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041913" ], "products": [ "species_10041915" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001347", "ENSBTAT00000001347" ] }, "reaction_10040489": { "compartment": "compartment_17963", "id": "reaction_10040489", "reactome": "R-BTA-187020", "name": "Part of pro-beta-NGF is processed to mature beta-NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040476" ], "products": [ "species_10040480" ], "modifiers": [ [ "species_10040486", "catalyst" ] ], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "species_74016", "A0A3Q1MCD7", "ENSBTAT00000077745" ] }, "reaction_10040495": { "compartment": "compartment_984", "id": "reaction_10040495", "reactome": "R-BTA-187035", "name": "Pro-beta-NGF and mature beta-NGF are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040480", "species_10040476" ], "products": [ "species_10039264", "species_10040493" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10090722": { "compartment": "compartment_876", "id": "reaction_10090722", "reactome": "R-BTA-9603419", "name": "Activated NTRK3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090663", "species_10090411" ], "products": [ "species_10090720" ], "modifiers": [], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090727": { "compartment": "compartment_876", "id": "reaction_10090727", "reactome": "R-BTA-9603420", "name": "Activated NTRK3 promotes SRC autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090720" ], "products": [ "species_10090724", "species_29370" ], "modifiers": [ [ "species_10090720", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090666": { "compartment": "compartment_876", "id": "reaction_10090666", "reactome": "R-BTA-9034714", "name": "NTRK3 dimers trans-autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090654" ], "products": [ "species_10090663", "species_29370" ], "modifiers": [ [ "species_10090654", "catalyst" ] ], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090675": { "compartment": "compartment_876", "id": "reaction_10090675", "reactome": "R-BTA-9034855", "name": "Activated PCLG1 dissociates from NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090673" ], "products": [ "species_10090663", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000023383" ] }, "reaction_10073244": { "compartment": "compartment_70101", "id": "reaction_10073244", "reactome": "R-BTA-5654730", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065269" ], "products": [ "species_10073210" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073215": { "compartment": "compartment_70101", "id": "reaction_10073215", "reactome": "R-BTA-5654679", "name": "CBL ubiquitinates FRS2 and FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073210" ], "products": [ "species_10073212" ], "modifiers": [ [ "species_10073210", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057337": { "compartment": "compartment_70101", "id": "reaction_10057337", "reactome": "R-BTA-1295632", "name": "PPA2A dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057334" ], "products": [ "species_10057300", "species_29372" ], "modifiers": [ [ "species_10057334", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057323": { "compartment": "compartment_70101", "id": "reaction_10057323", "reactome": "R-BTA-1295613", "name": "SPRY2 binds GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057316", "species_10035485" ], "products": [ "species_10057321" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10053082": { "compartment": "compartment_70101", "id": "reaction_10053082", "reactome": "R-BTA-934604", "name": "Phosphorylated SPRY2 is ubiquitinated by CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053077", "species_10033408" ], "products": [ "species_10053079" ], "modifiers": [ [ "species_10053077", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057327": { "compartment": "compartment_70101", "id": "reaction_10057327", "reactome": "R-BTA-1295621", "name": "CBL dissociates from ubiquitinated p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053079" ], "products": [ "species_10040359", "species_10057325" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10057329": { "compartment": "compartment_70101", "id": "reaction_10057329", "reactome": "R-BTA-1295622", "name": "SPRY2 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10057316" ], "products": [ "species_10053062", "species_10053077" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057314": { "compartment": "compartment_70101", "id": "reaction_10057314", "reactome": "R-BTA-1295604", "name": "B-RAF dissociates from S111/S120 p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057312" ], "products": [ "species_10057310", "species_10057306" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000086962", "ENSBTAT00000002324" ] }, "reaction_10059156": { "compartment": "compartment_70101", "id": "reaction_10059156", "reactome": "R-BTA-1549564", "name": "PPTN11 dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057321" ], "products": [ "species_10057316", "species_10035485" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "ENSBTAT00000002653" ] }, "reaction_10057302": { "compartment": "compartment_70101", "id": "reaction_10057302", "reactome": "R-BTA-1295599", "name": "SPRY2 translocates to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057300" ], "products": [ "species_10053066" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057318": { "compartment": "compartment_70101", "id": "reaction_10057318", "reactome": "R-BTA-1295609", "name": "SRC phosphorylates SPRY2 on Y55 and Y227", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10053066" ], "products": [ "species_10057316", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ], [ "species_10053072", "inhibitor" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000011767", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10040761": { "compartment": "compartment_984", "id": "reaction_10040761", "reactome": "R-BTA-190263", "name": "FGFR3b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040755", "species_10036461", "species_190915" ], "products": [ "species_10040759" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040779": { "compartment": "compartment_876", "id": "reaction_10040779", "reactome": "R-BTA-190385", "name": "Autocatalytic phosphorylation of FGFR3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040759", "species_113592" ], "products": [ "species_29370", "species_10036473" ], "modifiers": [ [ "species_10040759", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10083933": { "compartment": "compartment_17963", "id": "reaction_10083933", "reactome": "R-BTA-8851619", "name": "GALNT3 transfers GalNAc to FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10083928" ], "products": [ "species_205687", "species_10083930" ], "modifiers": [ [ "species_10052428", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940", "ENSBTAT00000018541" ] }, "reaction_10083935": { "compartment": "compartment_17963", "id": "reaction_10083935", "reactome": "R-BTA-8851632", "name": "GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083930" ], "products": [ "species_10036373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940" ] }, "reaction_10040782": { "compartment": "compartment_876", "id": "reaction_10040782", "reactome": "R-BTA-190388", "name": "Autocatalytic phosphorylation of FGFR3c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040751" ], "products": [ "species_10036485", "species_29370" ], "modifiers": [ [ "species_10040751", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040753": { "compartment": "compartment_984", "id": "reaction_10040753", "reactome": "R-BTA-190261", "name": "FGFR3c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040747", "species_10036475", "species_190915" ], "products": [ "species_10040751" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10073240": { "compartment": "compartment_70101", "id": "reaction_10073240", "reactome": "R-BTA-5654717", "name": "FGFR4-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065247", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073192": { "compartment": "compartment_70101", "id": "reaction_10073192", "reactome": "R-BTA-5654669", "name": "Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073188", "species_10035515" ], "products": [ "species_10073190" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073237": { "compartment": "compartment_70101", "id": "reaction_10073237", "reactome": "R-BTA-5654714", "name": "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10073190", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073177": { "compartment": "compartment_876", "id": "reaction_10073177", "reactome": "R-BTA-5654658", "name": "Activated FGFR4:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10073168" ], "products": [ "species_10073170" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073166": { "compartment": "compartment_876", "id": "reaction_10073166", "reactome": "R-BTA-5654653", "name": "Activated FGFR4 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073161" ], "products": [ "species_29370", "species_10073163" ], "modifiers": [ [ "species_10073161", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073182": { "compartment": "compartment_70101", "id": "reaction_10073182", "reactome": "R-BTA-5654663", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073179", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073184": { "compartment": "compartment_70101", "id": "reaction_10073184", "reactome": "R-BTA-5654664", "name": "Activated FGFR4:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073168" ], "products": [ "species_10073179" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073028": { "compartment": "compartment_876", "id": "reaction_10073028", "reactome": "R-BTA-5654418", "name": "Activated FGFR4 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073023" ], "products": [ "species_29370", "species_10065243" ], "modifiers": [ [ "species_10073023", "catalyst" ], [ "species_10073026", "inhibitor" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073031": { "compartment": "compartment_70101", "id": "reaction_10073031", "reactome": "R-BTA-5654422", "name": "Activated FGFR4 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10065241" ], "products": [ "species_10073023" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073175": { "compartment": "compartment_876", "id": "reaction_10073175", "reactome": "R-BTA-5654655", "name": "Activated FGFR4 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073170", "species_113592" ], "products": [ "species_10073172", "species_29370" ], "modifiers": [ [ "species_10073170", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087367": { "compartment": "compartment_70101", "id": "reaction_10087367", "reactome": "R-BTA-8941613", "name": "Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073172", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10072939": { "compartment": "compartment_876", "id": "reaction_10072939", "reactome": "R-BTA-5654169", "name": "p-4Y-PLCG1 dissociates from activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072924" ], "products": [ "species_10043237", "species_10065241" ], "modifiers": [], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072927": { "compartment": "compartment_70101", "id": "reaction_10072927", "reactome": "R-BTA-5654151", "name": "Activated FGFR4 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072922" ], "products": [ "species_29370", "species_10072924" ], "modifiers": [ [ "species_10072922", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10072933": { "compartment": "compartment_876", "id": "reaction_10072933", "reactome": "R-BTA-5654163", "name": "Activated FGFR4 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10061098", "species_10065241" ], "products": [ "species_10072922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10073246": { "compartment": "compartment_70101", "id": "reaction_10073246", "reactome": "R-BTA-5654734", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10073186" ], "products": [ "species_10073217" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073222": { "compartment": "compartment_70101", "id": "reaction_10073222", "reactome": "R-BTA-5654684", "name": "CBL ubiquitinates FRS2 and FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073217" ], "products": [ "species_10073219" ], "modifiers": [ [ "species_10073217", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040776": { "compartment": "compartment_876", "id": "reaction_10040776", "reactome": "R-BTA-190326", "name": "Autocatalytic phosphorylation of FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040767" ], "products": [ "species_10036502", "species_29370" ], "modifiers": [ [ "species_10040767", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10040769": { "compartment": "compartment_984", "id": "reaction_10040769", "reactome": "R-BTA-190265", "name": "FGFR4 binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036500", "species_10040763", "species_190915" ], "products": [ "species_10040767" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10057704": { "compartment": "compartment_70101", "id": "reaction_10057704", "reactome": "R-BTA-1307955", "name": "FGFR4 binds HS:KLB:FGF19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036498", "species_10036506", "species_10040763", "species_190915" ], "products": [ "species_10057702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022973", "ENSBTAT00000019297", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10057707": { "compartment": "compartment_876", "id": "reaction_10057707", "reactome": "R-BTA-1307963", "name": "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057702", "species_113592" ], "products": [ "species_29370", "species_10036508" ], "modifiers": [ [ "species_10057702", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10040720": { "compartment": "compartment_876", "id": "reaction_10040720", "reactome": "R-BTA-190258", "name": "FGFR2c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036438", "species_10040706", "species_190915" ], "products": [ "species_10040718" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000072473", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040788": { "compartment": "compartment_876", "id": "reaction_10040788", "reactome": "R-BTA-190413", "name": "Autocatalytic phosphorylation of FGFR2c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040718" ], "products": [ "species_29370", "species_10036459" ], "modifiers": [ [ "species_10040718", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040744": { "compartment": "compartment_876", "id": "reaction_10040744", "reactome": "R-BTA-190260", "name": "FGFR2b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036405", "species_10040722", "species_190915" ], "products": [ "species_10040734" ], "modifiers": [ [ "species_190915", "catalyst" ], [ "species_10040742", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000072473", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10040785": { "compartment": "compartment_876", "id": "reaction_10040785", "reactome": "R-BTA-190408", "name": "Autocatalytic phosphorylation of FGFR2b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040734" ], "products": [ "species_29370", "species_10036432" ], "modifiers": [ [ "species_10040734", "catalyst" ] ], "additional_components": [ "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10073328": { "compartment": "compartment_984", "id": "reaction_10073328", "reactome": "R-BTA-5656070", "name": "FGFBPs bind FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040740", "species_10040736" ], "products": [ "species_10040742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044642", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10072909": { "compartment": "compartment_70101", "id": "reaction_10072909", "reactome": "R-BTA-5654147", "name": "Activated FGFR2 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072904" ], "products": [ "species_29370", "species_10072906" ], "modifiers": [ [ "species_10072904", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072929": { "compartment": "compartment_876", "id": "reaction_10072929", "reactome": "R-BTA-5654157", "name": "p-4Y-PLCG1 dissociates from activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072906" ], "products": [ "species_10065255", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383" ] }, "reaction_10072931": { "compartment": "compartment_876", "id": "reaction_10072931", "reactome": "R-BTA-5654159", "name": "Activated FGFR2 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_179838", "species_10061098" ], "products": [ "species_10072904" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073001": { "compartment": "compartment_876", "id": "reaction_10073001", "reactome": "R-BTA-5654406", "name": "Activated FGFR2:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072988" ], "products": [ "species_10072990" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073004": { "compartment": "compartment_70101", "id": "reaction_10073004", "reactome": "R-BTA-5654407", "name": "Activated FGFR2 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072997", "species_113592" ], "products": [ "species_29370", "species_10072988" ], "modifiers": [ [ "species_10072997", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072993": { "compartment": "compartment_70101", "id": "reaction_10072993", "reactome": "R-BTA-5654402", "name": "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072990", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072999": { "compartment": "compartment_70101", "id": "reaction_10072999", "reactome": "R-BTA-5654404", "name": "Activated FGFR2 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072995" ], "products": [ "species_10072997" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073129": { "compartment": "compartment_876", "id": "reaction_10073129", "reactome": "R-BTA-5654608", "name": "Activated FGFR2:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065257" ], "products": [ "species_10073124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087370": { "compartment": "compartment_70101", "id": "reaction_10087370", "reactome": "R-BTA-8941618", "name": "Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065259", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073133": { "compartment": "compartment_70101", "id": "reaction_10073133", "reactome": "R-BTA-5654615", "name": "Activated FGFR2:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065257" ], "products": [ "species_10073131" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072976": { "compartment": "compartment_876", "id": "reaction_10072976", "reactome": "R-BTA-5654397", "name": "Activated FGFR2 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072961" ], "products": [ "species_29370", "species_10065257" ], "modifiers": [ [ "species_10072961", "catalyst" ], [ "species_10072974", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073136": { "compartment": "compartment_70101", "id": "reaction_10073136", "reactome": "R-BTA-5654618", "name": "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073131", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072979": { "compartment": "compartment_70101", "id": "reaction_10072979", "reactome": "R-BTA-5654399", "name": "Activated FGFR2 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072959" ], "products": [ "species_10072961" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073127": { "compartment": "compartment_876", "id": "reaction_10073127", "reactome": "R-BTA-5654607", "name": "Activated FGFR2 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073124", "species_113592" ], "products": [ "species_29370", "species_10065259" ], "modifiers": [ [ "species_10073124", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073231": { "compartment": "compartment_70101", "id": "reaction_10073231", "reactome": "R-BTA-5654697", "name": "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065263", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073208": { "compartment": "compartment_70101", "id": "reaction_10073208", "reactome": "R-BTA-5654677", "name": "CBL ubiquitinates FRS2 and FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073203", "species_10033408" ], "products": [ "species_10073205" ], "modifiers": [ [ "species_10073203", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073242": { "compartment": "compartment_70101", "id": "reaction_10073242", "reactome": "R-BTA-5654729", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065259" ], "products": [ "species_10073203" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073071": { "compartment": "compartment_876", "id": "reaction_10073071", "reactome": "R-BTA-5654510", "name": "FGFRL1 binds SPRED1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073053", "species_10073067" ], "products": [ "species_10073069" ], "modifiers": [], "additional_components": [ "F1MQI5", "ENSBTAT00000039444", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "F1MQI5", "ENSBTAT00000039444" ] }, "reaction_10073077": { "compartment": "compartment_876", "id": "reaction_10073077", "reactome": "R-BTA-5654511", "name": "FGFRL1 dimer binds FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073073", "species_10073053", "species_190915" ], "products": [ "species_10073075" ], "modifiers": [], "additional_components": [ "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MQI5", "ENSBTAT00000039444", "species_190915", "F1MQI5", "ENSBTAT00000039444", "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073199": { "compartment": "compartment_70101", "id": "reaction_10073199", "reactome": "R-BTA-5654672", "name": "CBL ubiquitinates FRS2 and FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073194" ], "products": [ "species_10073196" ], "modifiers": [ [ "species_10073194", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073201": { "compartment": "compartment_70101", "id": "reaction_10073201", "reactome": "R-BTA-5654673", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065249" ], "products": [ "species_10073194" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040794": { "compartment": "compartment_876", "id": "reaction_10040794", "reactome": "R-BTA-190429", "name": "Autocatalytic phosphorylation of FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040702" ], "products": [ "species_29370", "species_10036379" ], "modifiers": [ [ "species_10040702", "catalyst" ] ], "additional_components": [ "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040704": { "compartment": "compartment_984", "id": "reaction_10040704", "reactome": "R-BTA-190256", "name": "FGFR1c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036375", "species_10040698", "species_190915" ], "products": [ "species_10040702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "ENSBTAT00000083788", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040696": { "compartment": "compartment_984", "id": "reaction_10040696", "reactome": "R-BTA-190245", "name": "FGFR1b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040690", "species_190915", "species_10036328" ], "products": [ "species_10040694" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040791": { "compartment": "compartment_876", "id": "reaction_10040791", "reactome": "R-BTA-190427", "name": "Autocatalytic phosphorylation of FGFR1b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040694", "species_113592" ], "products": [ "species_29370", "species_10036344" ], "modifiers": [ [ "species_10040694", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040860": { "compartment": "compartment_876", "id": "reaction_10040860", "reactome": "R-BTA-191062", "name": "Autocatalytic phosphorylation of Klotho-bound FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040771", "species_113592" ], "products": [ "species_29370", "species_10036399" ], "modifiers": [ [ "species_10040771", "catalyst" ] ], "additional_components": [ "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040773": { "compartment": "compartment_984", "id": "reaction_10040773", "reactome": "R-BTA-190268", "name": "FGFR1c binds to Klotho-bound FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036397", "species_10040698", "species_190915" ], "products": [ "species_10040771" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10073097": { "compartment": "compartment_876", "id": "reaction_10073097", "reactome": "R-BTA-5654578", "name": "Activated FGFR1 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073094", "species_113592" ], "products": [ "species_10072950", "species_29370" ], "modifiers": [ [ "species_10073094", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073113": { "compartment": "compartment_876", "id": "reaction_10073113", "reactome": "R-BTA-5654587", "name": "Activated FGFR1:p-FRS phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073104" ], "products": [ "species_10073110", "species_29370" ], "modifiers": [ [ "species_10073104", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073083": { "compartment": "compartment_70101", "id": "reaction_10073083", "reactome": "R-BTA-5654569", "name": "Activated FGFR1 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10072959" ], "products": [ "species_10073079" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072957": { "compartment": "compartment_70101", "id": "reaction_10072957", "reactome": "R-BTA-5654392", "name": "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072954", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10087373": { "compartment": "compartment_70101", "id": "reaction_10087373", "reactome": "R-BTA-8941623", "name": "Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073110", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073090": { "compartment": "compartment_876", "id": "reaction_10073090", "reactome": "R-BTA-5654575", "name": "Activated FGFR1 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073079", "species_113592" ], "products": [ "species_29370", "species_10065235" ], "modifiers": [ [ "species_10073079", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073106": { "compartment": "compartment_876", "id": "reaction_10073106", "reactome": "R-BTA-5654584", "name": "Activated FGFR1:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10072952" ], "products": [ "species_10073104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073108": { "compartment": "compartment_70101", "id": "reaction_10073108", "reactome": "R-BTA-5654586", "name": "Activated FGFR1:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072952" ], "products": [ "species_10072954" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073225": { "compartment": "compartment_70101", "id": "reaction_10073225", "reactome": "R-BTA-5654690", "name": "FGFR1-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065239", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073115": { "compartment": "compartment_70101", "id": "reaction_10073115", "reactome": "R-BTA-5654596", "name": "Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065251", "species_10035515" ], "products": [ "species_10065253" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073228": { "compartment": "compartment_70101", "id": "reaction_10073228", "reactome": "R-BTA-5654692", "name": "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065253", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073087": { "compartment": "compartment_70101", "id": "reaction_10073087", "reactome": "R-BTA-5654573", "name": "Activated FGFR1 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065233" ], "products": [ "species_10073085" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073119": { "compartment": "compartment_876", "id": "reaction_10073119", "reactome": "R-BTA-5654597", "name": "Activated FGFR1:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073099" ], "products": [ "species_10073117" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073102": { "compartment": "compartment_70101", "id": "reaction_10073102", "reactome": "R-BTA-5654582", "name": "Activated FGFR1 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073085" ], "products": [ "species_29370", "species_10073099" ], "modifiers": [ [ "species_10073085", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073122": { "compartment": "compartment_70101", "id": "reaction_10073122", "reactome": "R-BTA-5654600", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073117", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073326": { "compartment": "compartment_876", "id": "reaction_10073326", "reactome": "R-BTA-5656064", "name": "Activated FGFR1 binds FLRT1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10073322" ], "products": [ "species_10073324" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072937": { "compartment": "compartment_876", "id": "reaction_10072937", "reactome": "R-BTA-5654167", "name": "Activated FGFR1 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065233", "species_10061098" ], "products": [ "species_10072915" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072920": { "compartment": "compartment_70101", "id": "reaction_10072920", "reactome": "R-BTA-5654149", "name": "Activated FGFR1 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072915", "species_113592" ], "products": [ "species_10072917", "species_29370" ], "modifiers": [ [ "species_10072915", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072935": { "compartment": "compartment_876", "id": "reaction_10072935", "reactome": "R-BTA-5654165", "name": "p-4Y-PLCG1 dissociates from activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072917" ], "products": [ "species_10043237", "species_10065233" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10091689": { "compartment": "compartment_876", "id": "reaction_10091689", "reactome": "R-BTA-9674095", "name": "PDGFRs bind type II TKI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9674079", "species_10040472" ], "products": [ "species_10091687" ], "modifiers": [], "additional_components": [ "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976", "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976" ] }, "reaction_10046666": { "compartment": "compartment_984", "id": "reaction_10046666", "reactome": "R-BTA-382057", "name": "Release of novel PDGFs as latent factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046658" ], "products": [ "species_10046664" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10046677": { "compartment": "compartment_984", "id": "reaction_10046677", "reactome": "R-BTA-382061", "name": "Extracellular processing of novel PDGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046664" ], "products": [ "species_10046672", "species_10046670" ], "modifiers": [ [ "species_10046674", "catalyst" ] ], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10046660": { "compartment": "compartment_20699", "id": "reaction_10046660", "reactome": "R-BTA-382053", "name": "Translocation of PDGF from ER to Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046654" ], "products": [ "species_10046658" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10057850": { "compartment": "compartment_876", "id": "reaction_10057850", "reactome": "R-BTA-1433454", "name": "Phosphorylation of GAB2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043813", "species_113592" ], "products": [ "species_10057847", "species_29370" ], "modifiers": [ [ "species_10043813", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1M864", "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10057854": { "compartment": "compartment_876", "id": "reaction_10057854", "reactome": "R-BTA-1433456", "name": "Recruitment of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057840", "species_10046556" ], "products": [ "species_10057852" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057872": { "compartment": "compartment_876", "id": "reaction_10057872", "reactome": "R-BTA-1433514", "name": "Synthesis of PIP3 from PIP2 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057869", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10058480": { "compartment": "compartment_876", "id": "reaction_10058480", "reactome": "R-BTA-1470012", "name": "Disassociation and translocation of STATs to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058476" ], "products": [ "species_10057840", "species_10052345" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10091667": { "compartment": "compartment_876", "id": "reaction_10091667", "reactome": "R-BTA-9669854", "name": "KIT binds type II TKIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9669722" ], "products": [ "species_10091665" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057845": { "compartment": "compartment_876", "id": "reaction_10057845", "reactome": "R-BTA-1433428", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043807", "species_10035485" ], "products": [ "species_10043809" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10043832": { "compartment": "compartment_876", "id": "reaction_10043832", "reactome": "R-BTA-205244", "name": "Recruitment of CBL to KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10043828" ], "products": [ "species_10043830" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057867": { "compartment": "compartment_876", "id": "reaction_10057867", "reactome": "R-BTA-1433506", "name": "Phosphorylation of APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057864" ], "products": [ "species_10043826", "species_29370" ], "modifiers": [ [ "species_10057864", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781" ] }, "reaction_10058474": { "compartment": "compartment_876", "id": "reaction_10058474", "reactome": "R-BTA-1470009", "name": "Phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057852" ], "products": [ "species_10058471", "species_29370" ], "modifiers": [ [ "species_10057852", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10058478": { "compartment": "compartment_876", "id": "reaction_10058478", "reactome": "R-BTA-1470010", "name": "Dimerization of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058471" ], "products": [ "species_10058476" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10057857": { "compartment": "compartment_876", "id": "reaction_10057857", "reactome": "R-BTA-1433471", "name": "Activation of RAS by p-KIT bound SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10043817", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10043815": { "compartment": "compartment_876", "id": "reaction_10043815", "reactome": "R-BTA-205234", "name": "Indirect recruitment of GAB2 to p-KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10043809" ], "products": [ "species_10043813" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10091751": { "compartment": "compartment_876", "id": "reaction_10091751", "reactome": "R-BTA-9681375", "name": "KIT binds ripretinib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9674322" ], "products": [ "species_10091749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057862": { "compartment": "compartment_876", "id": "reaction_10057862", "reactome": "R-BTA-1433488", "name": "Phosphorylation of SHP2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057859", "species_113592" ], "products": [ "species_29370", "species_10043807" ], "modifiers": [ [ "species_10057859", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10041657": { "compartment": "compartment_876", "id": "reaction_10041657", "reactome": "R-BTA-195408", "name": "NRP-1 forms a ternary complex with VEGF165 and VEGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041653", "species_10041457" ], "products": [ "species_10041655" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026471", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "E1BMX5", "ENSBTAT00000026471" ] }, "reaction_10041649": { "compartment": "compartment_984", "id": "reaction_10041649", "reactome": "R-BTA-195378", "name": "Homodimerization of VEGF proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041441" ], "products": [ "species_10041443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019613", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10070651": { "compartment": "compartment_876", "id": "reaction_10070651", "reactome": "R-BTA-5218820", "name": "Src kinases phosphorylate VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070647", "species_113592" ], "products": [ "species_29370", "species_10070649" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070589": { "compartment": "compartment_876", "id": "reaction_10070589", "reactome": "R-BTA-5218640", "name": "SRC-1 phosphorylates p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070580", "species_113592" ], "products": [ "species_29370", "species_10070586" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070657": { "compartment": "compartment_876", "id": "reaction_10070657", "reactome": "R-BTA-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070655" ], "products": [ "species_29370", "species_10070605" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "ENSBTAT00000039221" ] }, "reaction_10070628": { "compartment": "compartment_70101", "id": "reaction_10070628", "reactome": "R-BTA-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070612", "species_112275", "species_74016" ], "products": [ "species_10070626" ], "modifiers": [], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_74016", "species_112275", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10070615": { "compartment": "compartment_70101", "id": "reaction_10070615", "reactome": "R-BTA-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070605" ], "products": [ "species_10070612", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10069535": { "compartment": "compartment_876", "id": "reaction_10069535", "reactome": "R-BTA-4420206", "name": "Phosphorylation of SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069530" ], "products": [ "species_29370", "species_10069532" ], "modifiers": [ [ "species_10069530", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071504": { "compartment": "compartment_876", "id": "reaction_10071504", "reactome": "R-BTA-5357429", "name": "AXL autophosphorylates on Y772 and Y814", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071501" ], "products": [ "species_29370", "species_10070638" ], "modifiers": [ [ "species_10071501", "catalyst" ] ], "additional_components": [ "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071506": { "compartment": "compartment_876", "id": "reaction_10071506", "reactome": "R-BTA-5357432", "name": "AXL binds SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069532", "species_10071499" ], "products": [ "species_10071501" ], "modifiers": [], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10070645": { "compartment": "compartment_876", "id": "reaction_10070645", "reactome": "R-BTA-5218819", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10070642", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10071508": { "compartment": "compartment_876", "id": "reaction_10071508", "reactome": "R-BTA-5357479", "name": "p-AXL binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10070638" ], "products": [ "species_10070640" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10070676": { "compartment": "compartment_876", "id": "reaction_10070676", "reactome": "R-BTA-5218847", "name": "PAK2 binds NCK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047604", "species_10070672" ], "products": [ "species_10070674" ], "modifiers": [], "additional_components": [ "A0A3Q1M0G8", "ENSBTAT00000082239", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10070624": { "compartment": "compartment_876", "id": "reaction_10070624", "reactome": "R-BTA-5218806", "name": "FYN autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070619" ], "products": [ "species_29370", "species_10070621" ], "modifiers": [ [ "species_10070619", "catalyst" ] ], "additional_components": [ "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10070594": { "compartment": "compartment_70101", "id": "reaction_10070594", "reactome": "R-BTA-5218642", "name": "PTK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070591" ], "products": [ "species_10070578", "species_29370" ], "modifiers": [ [ "species_10070591", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070596": { "compartment": "compartment_876", "id": "reaction_10070596", "reactome": "R-BTA-5218645", "name": "SRC-1 binds p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070578", "species_10040957" ], "products": [ "species_10070580" ], "modifiers": [], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10056781": { "compartment": "compartment_876", "id": "reaction_10056781", "reactome": "R-BTA-1236398", "name": "ERBB4 binds NRGs or EGF-like ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056771", "species_10056765" ], "products": [ "species_10056779" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057151": { "compartment": "compartment_984", "id": "reaction_10057151", "reactome": "R-BTA-1250220", "name": "Homodimerization of ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056779" ], "products": [ "species_10057149" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057166": { "compartment": "compartment_70101", "id": "reaction_10057166", "reactome": "R-BTA-1250315", "name": "Trans-autophosphorylation of ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057149" ], "products": [ "species_29370", "species_10057163" ], "modifiers": [ [ "species_10057149", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057184": { "compartment": "compartment_876", "id": "reaction_10057184", "reactome": "R-BTA-1250370", "name": "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057181", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "P32871", "ENSBTAT00000072391" ] }, "reaction_10090971": { "compartment": "compartment_876", "id": "reaction_10090971", "reactome": "R-BTA-9612219", "name": "ERBB4s80 binds to SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10057211" ], "products": [ "species_10057250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057262": { "compartment": "compartment_70101", "id": "reaction_10057262", "reactome": "R-BTA-1253282", "name": "ERBB4 ubiquitination by WWP1/ITCH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10057257" ], "products": [ "species_10057259" ], "modifiers": [ [ "species_10057257", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057264": { "compartment": "compartment_876", "id": "reaction_10057264", "reactome": "R-BTA-1253300", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055126", "species_10057255" ], "products": [ "species_10057257" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057272": { "compartment": "compartment_70101", "id": "reaction_10057272", "reactome": "R-BTA-1253343", "name": "WWOX binds ERBB4s80", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10057211" ], "products": [ "species_10057270" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10057298": { "compartment": "compartment_70101", "id": "reaction_10057298", "reactome": "R-BTA-1254376", "name": "Translocation of cytosolic ERBB4s80 to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057296" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057236": { "compartment": "compartment_70101", "id": "reaction_10057236", "reactome": "R-BTA-1251997", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057201" ], "products": [ "species_10057211" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10057252": { "compartment": "compartment_70101", "id": "reaction_10057252", "reactome": "R-BTA-1252013", "name": "Translocation of ERBB4s80 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057246" ], "modifiers": [ [ "species_10057250", "inhibitor" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057284": { "compartment": "compartment_70101", "id": "reaction_10057284", "reactome": "R-BTA-1254248", "name": "Translocation of ERBB4s80:YAP1 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057278" ], "products": [ "species_10057282" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10057286": { "compartment": "compartment_70101", "id": "reaction_10057286", "reactome": "R-BTA-1254251", "name": "ERBB4s80 binds YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276", "species_10057211" ], "products": [ "species_10057278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10084080": { "compartment": "compartment_984", "id": "reaction_10084080", "reactome": "R-BTA-8852552", "name": "MST1R autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084065" ], "products": [ "species_29370", "species_10084077" ], "modifiers": [ [ "species_10084065", "catalyst" ] ], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10084067": { "compartment": "compartment_984", "id": "reaction_10084067", "reactome": "R-BTA-8852522", "name": "MST1 dimer:MST1R dimer binds MST1R dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080868", "species_10080866" ], "products": [ "species_10084065" ], "modifiers": [], "additional_components": [ "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10080870": { "compartment": "compartment_876", "id": "reaction_10080870", "reactome": "R-BTA-6800315", "name": "MST1 binds MST1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080866", "species_10080858" ], "products": [ "species_10080868" ], "modifiers": [], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028" ] }, "reaction_10091705": { "compartment": "compartment_459", "id": "reaction_10091705", "reactome": "R-BTA-9674531", "name": "AAMP binds EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091695", "species_10040201" ], "products": [ "species_10091703" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005126", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3SZK1", "ENSBTAT00000005126" ] }, "reaction_10040393": { "compartment": "compartment_70101", "id": "reaction_10040393", "reactome": "R-BTA-182993", "name": "Ubiquitination of stimulated EGFR (CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040366" ], "products": [ "species_10040388" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040458": { "compartment": "compartment_70101", "id": "reaction_10040458", "reactome": "R-BTA-183058", "name": "Phosphorylation of CBL (EGFR:GRB2:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040455", "species_113592" ], "products": [ "species_29370", "species_10040395" ], "modifiers": [ [ "species_10040455", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040460": { "compartment": "compartment_70101", "id": "reaction_10040460", "reactome": "R-BTA-183067", "name": "Localization of CBL:GRB2 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10040449" ], "products": [ "species_10040455" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040447": { "compartment": "compartment_70101", "id": "reaction_10040447", "reactome": "R-BTA-183051", "name": "CBL ubiquitinates Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040440" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040440", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10040462": { "compartment": "compartment_70101", "id": "reaction_10040462", "reactome": "R-BTA-183089", "name": "CBL binds and ubiquitinates phosphorylated Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040382", "species_10040366" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040369": { "compartment": "compartment_70101", "id": "reaction_10040369", "reactome": "R-BTA-182969", "name": "Phosphorylation of CBL (EGFR:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040361" ], "products": [ "species_29370", "species_10040366" ], "modifiers": [ [ "species_10040361", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040432": { "compartment": "compartment_70101", "id": "reaction_10040432", "reactome": "R-BTA-183036", "name": "Ubiquitination of stimulated EGFR (CBL:GRB2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040395" ], "products": [ "species_10040425" ], "modifiers": [ [ "species_10040395", "catalyst" ], [ "species_10040430", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000061187" ] }, "reaction_10040451": { "compartment": "compartment_70101", "id": "reaction_10040451", "reactome": "R-BTA-183052", "name": "CBL binds to GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10035485" ], "products": [ "species_10040449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040386": { "compartment": "compartment_876", "id": "reaction_10040386", "reactome": "R-BTA-182988", "name": "Sprouty lures CBL away from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040374", "species_10040359" ], "products": [ "species_10040384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002324", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040453": { "compartment": "compartment_876", "id": "reaction_10040453", "reactome": "R-BTA-183055", "name": "Binding of CBL to EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10040243" ], "products": [ "species_10040361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040421": { "compartment": "compartment_70101", "id": "reaction_10040421", "reactome": "R-BTA-182994", "name": "Assembly of EGFR complex in clathrin-coated vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040417", "species_10040395" ], "products": [ "species_10040419" ], "modifiers": [], "additional_components": [ "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040331": { "compartment": "compartment_70101", "id": "reaction_10040331", "reactome": "R-BTA-177945", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040301", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040303": { "compartment": "compartment_70101", "id": "reaction_10040303", "reactome": "R-BTA-177936", "name": "GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10040283" ], "products": [ "species_10040301" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040286": { "compartment": "compartment_70101", "id": "reaction_10040286", "reactome": "R-BTA-177933", "name": "SHC1 phosphorylation by phosphorylated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040256", "species_113592" ], "products": [ "species_29370", "species_10040283" ], "modifiers": [ [ "species_10040256", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040258": { "compartment": "compartment_70101", "id": "reaction_10040258", "reactome": "R-BTA-177925", "name": "SHC1 binds to the phosphorylated EGF receptor:ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035544" ], "products": [ "species_10040256" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040289": { "compartment": "compartment_70101", "id": "reaction_10040289", "reactome": "R-BTA-177934", "name": "EGFR autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040227", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10036616": { "compartment": "compartment_70101", "id": "reaction_10036616", "reactome": "R-BTA-109813", "name": "GRB2-1 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10035485" ], "products": [ "species_10035491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040317": { "compartment": "compartment_70101", "id": "reaction_10040317", "reactome": "R-BTA-177938", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040314", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040326": { "compartment": "compartment_70101", "id": "reaction_10040326", "reactome": "R-BTA-177943", "name": "GRB2:SOS1 complex binds to EGF:EGFR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035491" ], "products": [ "species_10040314" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040323": { "compartment": "compartment_984", "id": "reaction_10040323", "reactome": "R-BTA-177942", "name": "EGFR binds EGF ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040223", "species_10040201" ], "products": [ "species_10040225" ], "modifiers": [ [ "species_10040321", "inhibitor" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000030750" ] }, "reaction_10040229": { "compartment": "compartment_876", "id": "reaction_10040229", "reactome": "R-BTA-177922", "name": "EGFR dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040225" ], "products": [ "species_10040227" ], "modifiers": [], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10044472": { "compartment": "compartment_876", "id": "reaction_10044472", "reactome": "R-BTA-212713", "name": "Active PLC-gamma1 dissociates from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044467" ], "products": [ "species_10043237", "species_10040243" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044465": { "compartment": "compartment_876", "id": "reaction_10044465", "reactome": "R-BTA-212706", "name": "Phospholipase C-gamma1 binds to the activated EGF receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043197" ], "products": [ "species_10044463" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044470": { "compartment": "compartment_70101", "id": "reaction_10044470", "reactome": "R-BTA-212710", "name": "EGFR activates PLC-gamma1 by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044463" ], "products": [ "species_29370", "species_10044467" ], "modifiers": [ [ "species_10044463", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040310": { "compartment": "compartment_70101", "id": "reaction_10040310", "reactome": "R-BTA-177937", "name": "Phosphorylation of EGFR by SRC kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000011767" ] }, "reaction_10035536": { "compartment": "compartment_70101", "id": "reaction_10035536", "reactome": "R-BTA-74746", "name": "GRB2-1:SOS1 binds p-Y427-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035532" ], "products": [ "species_10035534" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10075065": { "compartment": "compartment_70101", "id": "reaction_10075065", "reactome": "R-BTA-5686074", "name": "GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036626" ], "products": [ "species_10036624", "species_10035532" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "ENSBTAT00000075224" ] }, "reaction_10075097": { "compartment": "compartment_70101", "id": "reaction_10075097", "reactome": "R-BTA-5686315", "name": "GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036628" ], "products": [ "species_10036624", "species_10035503" ], "modifiers": [], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10083487": { "compartment": "compartment_70101", "id": "reaction_10083487", "reactome": "R-BTA-8848110", "name": "SOCS3 binds activated PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051731", "species_10083480" ], "products": [ "species_10083485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011106", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q9BEG9", "ENSBTAT00000011106" ] }, "reaction_10083565": { "compartment": "compartment_70101", "id": "reaction_10083565", "reactome": "R-BTA-8848436", "name": "PTK6 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083556", "species_113592" ], "products": [ "species_29370", "species_10083562", "species_10083480" ], "modifiers": [ [ "species_10083556", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083558": { "compartment": "compartment_70101", "id": "reaction_10083558", "reactome": "R-BTA-8848414", "name": "Activated PTK6 binds CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083554", "species_10083480" ], "products": [ "species_10083556" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083646": { "compartment": "compartment_70101", "id": "reaction_10083646", "reactome": "R-BTA-8848864", "name": "PTK6 binds ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083642", "species_10083480" ], "products": [ "species_10083644" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083632": { "compartment": "compartment_70101", "id": "reaction_10083632", "reactome": "R-BTA-8848818", "name": "PTK6 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_113592" ], "products": [ "species_29370", "species_10052267" ], "modifiers": [ [ "species_10083480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000061122" ] }, "reaction_10083652": { "compartment": "compartment_70101", "id": "reaction_10083652", "reactome": "R-BTA-8848873", "name": "PTK6 phosphorylates ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083644" ], "products": [ "species_29370", "species_10083649", "species_10083480" ], "modifiers": [ [ "species_10083644", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568", "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083638": { "compartment": "compartment_70101", "id": "reaction_10083638", "reactome": "R-BTA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10052267" ], "products": [ "species_10083635" ], "modifiers": [ [ "species_10052267", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000072559" ] }, "reaction_10083690": { "compartment": "compartment_70101", "id": "reaction_10083690", "reactome": "R-BTA-8849068", "name": "PTK6 phosphorylates ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083682", "species_113592" ], "products": [ "species_10083687", "species_29370", "species_10083480" ], "modifiers": [ [ "species_10083682", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083581": { "compartment": "compartment_70101", "id": "reaction_10083581", "reactome": "R-BTA-8848596", "name": "PTK6 binds PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070667", "species_10083480" ], "products": [ "species_10083579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083629": { "compartment": "compartment_70101", "id": "reaction_10083629", "reactome": "R-BTA-8848726", "name": "PTK6 phosphorylates BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083620", "species_113592" ], "products": [ "species_29370", "species_10083626", "species_10083480" ], "modifiers": [ [ "species_10083620", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322", "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083695": { "compartment": "compartment_70101", "id": "reaction_10083695", "reactome": "R-BTA-8849082", "name": "ARHGAP35 stimulates RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083692" ], "products": [ "species_10083687", "species_29372", "species_10037313" ], "modifiers": [ [ "species_10083692", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083697": { "compartment": "compartment_70101", "id": "reaction_10083697", "reactome": "R-BTA-8849085", "name": "ARHGAP35 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083687", "species_10037315" ], "products": [ "species_10083692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083588": { "compartment": "compartment_70101", "id": "reaction_10083588", "reactome": "R-BTA-8848606", "name": "PTK6 phosphorylates PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083579" ], "products": [ "species_29370", "species_10083585", "species_10083480" ], "modifiers": [ [ "species_10083579", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101", "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083684": { "compartment": "compartment_70101", "id": "reaction_10083684", "reactome": "R-BTA-8849055", "name": "PTK6 binds ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083680", "species_10083480" ], "products": [ "species_10083682" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083622": { "compartment": "compartment_70101", "id": "reaction_10083622", "reactome": "R-BTA-8848713", "name": "PTK6 binds BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083618", "species_10083480" ], "products": [ "species_10083620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083707": { "compartment": "compartment_70101", "id": "reaction_10083707", "reactome": "R-BTA-8849102", "name": "SRMS phosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083480" ], "products": [ "species_10083700", "species_29370" ], "modifiers": [ [ "species_10083704", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000002574" ] }, "reaction_10083726": { "compartment": "compartment_70101", "id": "reaction_10083726", "reactome": "R-BTA-8849428", "name": "PTPN1 binds PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055952", "species_10083480" ], "products": [ "species_10083724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10083729": { "compartment": "compartment_70101", "id": "reaction_10083729", "reactome": "R-BTA-8849435", "name": "PTPN1 dephosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083724" ], "products": [ "species_29372", "species_10055952", "species_10083473" ], "modifiers": [ [ "species_10083724", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678", "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090428": { "compartment": "compartment_876", "id": "reaction_10090428", "reactome": "R-BTA-9021627", "name": "EPOR-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10090425", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10089841": { "compartment": "compartment_876", "id": "reaction_10089841", "reactome": "R-BTA-9012657", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047493", "species_10089837" ], "products": [ "species_10089839" ], "modifiers": [], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10090501": { "compartment": "compartment_876", "id": "reaction_10090501", "reactome": "R-BTA-9027272", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090415" ], "products": [ "species_29370", "species_10089837" ], "modifiers": [ [ "species_10090415", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10073851": { "compartment": "compartment_17938", "id": "reaction_10073851", "reactome": "R-BTA-5672828", "name": "mTORC1 phosphorylates AKT1S1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039143", "species_113592" ], "products": [ "species_29370", "species_10073848" ], "modifiers": [ [ "species_10039143", "catalyst" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046572": { "compartment": "compartment_70101", "id": "reaction_10046572", "reactome": "R-BTA-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042890", "species_76577" ], "products": [ "species_10046570" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10046588": { "compartment": "compartment_70101", "id": "reaction_10046588", "reactome": "R-BTA-380979", "name": "RHEB in mTORC1:RHEB:GTP hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_29372", "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046583": { "compartment": "compartment_70101", "id": "reaction_10046583", "reactome": "R-BTA-380949", "name": "AMPK is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10042890" ], "products": [ "species_29372", "species_10042880" ], "modifiers": [ [ "species_10046580", "catalyst" ] ], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MBG5", "ENSBTAT00000000017", "F1MQV7", "ENSBTAT00000024965", "ENSBTAT00000024128" ] }, "reaction_10049894": { "compartment": "compartment_876", "id": "reaction_10049894", "reactome": "R-BTA-447074", "name": "AMPK phosphorylates Raptor in the mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_113592" ], "products": [ "species_29370", "species_10039178" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10088493": { "compartment": "compartment_70101", "id": "reaction_10088493", "reactome": "R-BTA-8952716", "name": "SLC38A9 binds Ragulator:Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039075", "species_10039119" ], "products": [ "species_10039121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10073853": { "compartment": "compartment_17938", "id": "reaction_10073853", "reactome": "R-BTA-5672843", "name": "AKT1S1 (PRAS40) binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_10039145" ], "products": [ "species_10039147" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000007575", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10088496": { "compartment": "compartment_70101", "id": "reaction_10088496", "reactome": "R-BTA-8952726", "name": "SLC38A9 transports L-Arg from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428011" ], "products": [ "species_29468" ], "modifiers": [ [ "species_10039121", "catalyst" ] ], "additional_components": [ "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039059": { "compartment": "compartment_17938", "id": "reaction_10039059", "reactome": "R-BTA-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039055" ], "products": [ "species_29420", "species_10039057" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438" ] }, "reaction_10039209": { "compartment": "compartment_70101", "id": "reaction_10039209", "reactome": "R-BTA-165758", "name": "Phosphorylation and inactivation of eEF2K by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039204", "species_113592" ], "products": [ "species_10039207", "species_29370" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023487", "ENSBTAT00000023487", "ENSBTAT00000022415" ] }, "reaction_10039160": { "compartment": "compartment_70101", "id": "reaction_10039160", "reactome": "R-BTA-165708", "name": "Dissociation of phosphorylated 4EBP1 from eIF4E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039133" ], "products": [ "species_10034357", "species_10039131" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10091741": { "compartment": "compartment_70101", "id": "reaction_10091741", "reactome": "R-BTA-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10039151" ], "products": [ "species_10039153" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10039180": { "compartment": "compartment_17938", "id": "reaction_10039180", "reactome": "R-BTA-165718", "name": "mTORC1 phosphorylation of RPS6KB1 (S6K)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039164" ], "products": [ "species_29370", "species_10039168" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039178", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022415", "ENSBTAT00000022415", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10039200": { "compartment": "compartment_70101", "id": "reaction_10039200", "reactome": "R-BTA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034529" ], "products": [ "species_29370", "species_10039197" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1N412", "ENSBTAT00000019214", "ENSBTAT00000022415" ] }, "reaction_10039155": { "compartment": "compartment_17938", "id": "reaction_10039155", "reactome": "R-BTA-165692", "name": "Phosphorylation of 4E-BP1 by activated mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034363" ], "products": [ "species_29370", "species_10039133" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039147", "inhibitor" ] ], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072900": { "compartment": "compartment_70101", "id": "reaction_10072900", "reactome": "R-BTA-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039101", "species_10039115" ], "products": [ "species_10039117" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438" ] }, "reaction_10073844": { "compartment": "compartment_17938", "id": "reaction_10073844", "reactome": "R-BTA-5672824", "name": "Phosphorylated AKT1S1:mTORC1 binds YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039141", "species_10037666" ], "products": [ "species_10039143" ], "modifiers": [], "additional_components": [ "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039127": { "compartment": "compartment_70101", "id": "reaction_10039127", "reactome": "R-BTA-165680", "name": "Formation of active mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039123", "species_10039057" ], "products": [ "species_10039125" ], "modifiers": [], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072902": { "compartment": "compartment_70101", "id": "reaction_10072902", "reactome": "R-BTA-5653974", "name": "Ragulator binds Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039095", "species_10039117" ], "products": [ "species_10039119" ], "modifiers": [], "additional_components": [ "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10046602": { "compartment": "compartment_12045", "id": "reaction_10046602", "reactome": "R-BTA-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046594", "species_113592" ], "products": [ "species_10046599", "species_29370" ], "modifiers": [ [ "species_10046594", "catalyst" ] ], "additional_components": [ "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10046604": { "compartment": "compartment_12045", "id": "reaction_10046604", "reactome": "R-BTA-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046592" ], "products": [ "species_10046594" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10085865": { "compartment": "compartment_7660", "id": "reaction_10085865", "reactome": "R-BTA-8874849", "name": "CREBRF binds CREB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085861", "species_10085857" ], "products": [ "species_10085863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065187", "ENSBTAT00000015193", "Q8SQ19", "ENSBTAT00000015193", "E1BPS0", "ENSBTAT00000065187" ] }, "reaction_10060285": { "compartment": "compartment_161320", "id": "reaction_10060285", "reactome": "R-BTA-1630304", "name": "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2105007", "species_1605715" ], "products": [ "species_2104997", "species_1606845" ], "modifiers": [ [ "species_10060282", "catalyst" ] ], "additional_components": [ "F1MU84", "ENSBTAT00000006001" ] }, "reaction_10091293": { "compartment": "compartment_161320", "id": "reaction_10091293", "reactome": "R-BTA-9638078", "name": "HEXB cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060293": { "compartment": "compartment_161320", "id": "reaction_10060293", "reactome": "R-BTA-1638032", "name": "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2104995" ], "products": [ "species_1606845", "species_2105012" ], "modifiers": [ [ "species_10060290", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023218" ] }, "reaction_10060295": { "compartment": "compartment_161320", "id": "reaction_10060295", "reactome": "R-BTA-1638053", "name": "HEXA cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10063510": { "compartment": "compartment_984", "id": "reaction_10063510", "reactome": "R-BTA-2046239", "name": "Extracellular KSPG translocates to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063483" ], "products": [ "species_10060854" ], "modifiers": [], "additional_components": [ "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279" ] }, "reaction_10038201": { "compartment": "compartment_984", "id": "reaction_10038201", "reactome": "R-BTA-158311", "name": "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038157" ], "products": [ "species_10038198", "species_10038196", "species_10038188" ], "modifiers": [ [ "species_10038157", "catalyst" ] ], "additional_components": [ "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10091546": { "compartment": "compartment_17957", "id": "reaction_10091546", "reactome": "R-BTA-9650473", "name": "SERPING1 is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091544" ], "products": [ "species_10038209" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "ENSBTAT00000021638" ] }, "reaction_10038205": { "compartment": "compartment_984", "id": "reaction_10038205", "reactome": "R-BTA-158354", "name": "kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038143", "species_10038203" ], "products": [ "species_10038145" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10090718": { "compartment": "compartment_984", "id": "reaction_10090718", "reactome": "R-BTA-9603302", "name": "Factor IIa inhibitors (peptide) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603327", "species_10037577" ], "products": [ "species_10038217" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038129": { "compartment": "compartment_984", "id": "reaction_10038129", "reactome": "R-BTA-158145", "name": "factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037535", "species_10038121" ], "products": [ "species_10038127" ], "modifiers": [], "additional_components": [ "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945" ] }, "reaction_10091600": { "compartment": "compartment_17957", "id": "reaction_10091600", "reactome": "R-BTA-9661625", "name": "FVIII is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076686" ], "products": [ "species_10038115" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10091671": { "compartment": "compartment_984", "id": "reaction_10091671", "reactome": "R-BTA-9670014", "name": "Factor VIIIa dissociates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10091669", "species_10071930" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726", "ENSBTAT00000036726" ] }, "reaction_10038166": { "compartment": "compartment_876", "id": "reaction_10038166", "reactome": "R-BTA-158251", "name": "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038147" ], "products": [ "species_10038157" ], "modifiers": [ [ "species_10038163", "catalyst" ] ], "additional_components": [ "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "F1MAU4", "ENSBTAT00000047906" ] }, "reaction_10090185": { "compartment": "compartment_984", "id": "reaction_10090185", "reactome": "R-BTA-9015379", "name": "Factor IIa inhibitors (compounds) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603311", "species_10037577" ], "products": [ "species_10038215" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10071946": { "compartment": "compartment_984", "id": "reaction_10071946", "reactome": "R-BTA-5607043", "name": "factor VIIIa associates with cell membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10038174" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10038221": { "compartment": "compartment_984", "id": "reaction_10038221", "reactome": "R-BTA-158419", "name": "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038127" ], "products": [ "species_10038182" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ], [ "species_10038219", "inhibitor" ] ], "additional_components": [ "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038149": { "compartment": "compartment_876", "id": "reaction_10038149", "reactome": "R-BTA-158218", "name": "prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038133", "species_10038145" ], "products": [ "species_10038147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503" ] }, "reaction_10038213": { "compartment": "compartment_984", "id": "reaction_10038213", "reactome": "R-BTA-158399", "name": "kallikrein binds SERPING1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038209", "species_10038188" ], "products": [ "species_10038211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "E1BMJ0", "ENSBTAT00000021638" ] }, "reaction_10035301": { "compartment": "compartment_7660", "id": "reaction_10035301", "reactome": "R-BTA-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035297", "species_10035293" ], "products": [ "species_10035299" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006308", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "E1B883", "ENSBTAT00000006308" ] }, "reaction_10035254": { "compartment": "compartment_350", "id": "reaction_10035254", "reactome": "R-BTA-73718", "name": "UBF-1 Binds rDNA Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73682", "species_10035051" ], "products": [ "species_10035053" ], "modifiers": [ [ "species_10035231", "inhibitor" ], [ "species_10035252", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034806", "F1MCZ7", "ENSBTAT00000034806", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10034224": { "compartment": "compartment_70101", "id": "reaction_10034224", "reactome": "R-BTA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10034221", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P37980", "ENSBTAT00000010311" ] }, "reaction_10050169": { "compartment": "compartment_5460", "id": "reaction_10050169", "reactome": "R-BTA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10050166", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "A0A3Q1LXA8", "ENSBTAT00000086411" ] }, "reaction_10038107": { "compartment": "compartment_70101", "id": "reaction_10038107", "reactome": "R-BTA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10038103" ], "products": [ "species_10038105" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005581", "Q3SYU2", "ENSBTAT00000005581", "species_29438" ] }, "reaction_10038082": { "compartment": "compartment_70101", "id": "reaction_10038082", "reactome": "R-BTA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034837" ], "products": [ "species_10038080", "species_10034641" ], "modifiers": [], "additional_components": [ "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000035330" ] }, "reaction_10034365": { "compartment": "compartment_70101", "id": "reaction_10034365", "reactome": "R-BTA-72622", "name": "Release of eIF4E from the inactive eIF4E:4E-BP complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034363" ], "products": [ "species_10034357", "species_10034361" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10034855": { "compartment": "compartment_70101", "id": "reaction_10034855", "reactome": "R-BTA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034839", "species_10034853" ], "products": [ "species_10034853", "species_10034837", "species_10034609" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000023455", "ENSBTAT00000023455", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484" ] }, "reaction_10034905": { "compartment": "compartment_70101", "id": "reaction_10034905", "reactome": "R-BTA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034901", "species_10034385" ], "products": [ "species_10034903" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455" ] }, "reaction_10034383": { "compartment": "compartment_70101", "id": "reaction_10034383", "reactome": "R-BTA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10034379" ], "products": [ "species_10034381" ], "modifiers": [], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10034387": { "compartment": "compartment_70101", "id": "reaction_10034387", "reactome": "R-BTA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72393", "species_10034381" ], "products": [ "species_10034385" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10060894": { "compartment": "compartment_70101", "id": "reaction_10060894", "reactome": "R-BTA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060890", "species_10060888" ], "products": [ "species_10060892" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912" ] }, "reaction_10048380": { "compartment": "compartment_17957", "id": "reaction_10048380", "reactome": "R-BTA-421416", "name": "Proglucagon translocates from the ER Lumen to secretory granules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048376" ], "products": [ "species_10048378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972" ] }, "reaction_10046723": { "compartment": "compartment_984", "id": "reaction_10046723", "reactome": "R-BTA-383313", "name": "Glucagon-like Peptide 1 is secreted from intestinal L cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046709" ], "products": [ "species_10046626" ], "modifiers": [ [ "species_10046721", "catalyst" ], [ "species_10046044", "catalyst" ], [ "species_10046717", "catalyst" ], [ "species_10046130", "catalyst" ], [ "species_70115", "catalyst" ], [ "species_372533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972", "E1B8Q3", "ENSBTAT00000026313", "A0A3Q1NGS8", "ENSBTAT00000082648", "G1K1V2", "ENSBTAT00000023234", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "G5E5H9", "ENSBTAT00000019647", "species_8848483", "CHEBI:71466", "CHEBI:28716", "species_426576", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "CHEBI:16196", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560" ] }, "reaction_10045736": { "compartment": "compartment_984", "id": "reaction_10045736", "reactome": "R-BTA-378975", "name": "Follitropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045700", "species_10041260" ], "products": [ "species_10045702" ], "modifiers": [ [ "species_10045734", "catalyst" ], [ "species_10045722", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000014462", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04837", "ENSBTAT00000014462", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07994", "ENSBTAT00000013154" ] }, "reaction_10045694": { "compartment": "compartment_984", "id": "reaction_10045694", "reactome": "R-BTA-378952", "name": "Thyrotropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043952", "species_10041260" ], "products": [ "species_10043954" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008264", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10045744": { "compartment": "compartment_984", "id": "reaction_10045744", "reactome": "R-BTA-378978", "name": "CGA and CGB3 bind to form Human chorionic gonadotropin (hCG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041260", "species_10045740" ], "products": [ "species_10045742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078886", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10045696": { "compartment": "compartment_984", "id": "reaction_10045696", "reactome": "R-BTA-378956", "name": "Luteinizing hormone is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041265", "species_10041260" ], "products": [ "species_10041267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057054", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10091056": { "compartment": "compartment_984", "id": "reaction_10091056", "reactome": "R-BTA-9619024", "name": "CES1trimer hydrolyses ACEI pro-drugs to ACEIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_9619052" ], "products": [ "species_8878776", "species_9619021" ], "modifiers": [ [ "species_10076366", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461" ] }, "reaction_10048461": { "compartment": "compartment_17957", "id": "reaction_10048461", "reactome": "R-BTA-422051", "name": "Cleavage of the signal peptide of Preproghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048434" ], "products": [ "species_10048438" ], "modifiers": [ [ "species_10048458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "P67810", "ENSBTAT00000014925", "Q2KI36", "ENSBTAT00000015866", "A0A3Q1MLX7", "ENSBTAT00000083476", "E1BEI2", "ENSBTAT00000008726" ] }, "reaction_10048429": { "compartment": "compartment_876", "id": "reaction_10048429", "reactome": "R-BTA-422048", "name": "Acyl Ghrelin and C-Ghrelin are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048421", "species_10048413" ], "products": [ "species_10048423", "species_10046085" ], "modifiers": [ [ "species_10046613", "catalyst" ], [ "species_70115", "inhibitor" ], [ "species_10038908", "inhibitor" ], [ "species_10048427", "inhibitor" ], [ "species_422024", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000014713", "ENSBTAT00000000972", "ENSBTAT00000082606" ] }, "reaction_10048465": { "compartment": "compartment_17957", "id": "reaction_10048465", "reactome": "R-BTA-422104", "name": "Ghrelin O-acyltransferase octanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_422042", "species_10048398" ], "products": [ "species_10048463" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10048407": { "compartment": "compartment_17957", "id": "reaction_10048407", "reactome": "R-BTA-422017", "name": "Ghrelin O-acyltransferase decanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048398", "species_422019" ], "products": [ "species_10048400" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10049385": { "compartment": "compartment_1462052", "id": "reaction_10049385", "reactome": "R-BTA-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049382", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001343" ] }, "reaction_10049392": { "compartment": "compartment_20699", "id": "reaction_10049392", "reactome": "R-BTA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049389", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086579" ] }, "reaction_10085101": { "compartment": "compartment_70101", "id": "reaction_10085101", "reactome": "R-BTA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29404", "species_113592" ], "products": [ "species_10085076", "species_29372", "species_29370" ], "modifiers": [ [ "species_10085098", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "G3N2U5", "ENSBTAT00000064999", "A7E2Z5", "ENSBTAT00000017043", "E1BKB4", "ENSBTAT00000069658" ] }, "reaction_10085250": { "compartment": "compartment_70101", "id": "reaction_10085250", "reactome": "R-BTA-8867370", "name": "TTLL3, TTLL8, TTLL10 polyglycylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_113592", "species_29424" ], "products": [ "species_29372", "species_10085237", "species_29370" ], "modifiers": [ [ "species_10085247", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N325", "ENSBTAT00000034047", "G3N3S4", "ENSBTAT00000065735" ] }, "reaction_10087993": { "compartment": "compartment_70101", "id": "reaction_10087993", "reactome": "R-BTA-8952044", "name": "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087978" ], "products": [ "species_10087990", "species_10087869" ], "modifiers": [ [ "species_10087978", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MXH0", "ENSBTAT00000068692", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207" ] }, "reaction_10087848": { "compartment": "compartment_70101", "id": "reaction_10087848", "reactome": "R-BTA-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075935", "species_10087835" ], "products": [ "species_111294", "species_10087845", "species_76577" ], "modifiers": [ [ "species_10087835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10087883": { "compartment": "compartment_70101", "id": "reaction_10087883", "reactome": "R-BTA-8951764", "name": "Transfer of NEDD8 to AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087871" ], "products": [ "species_10087845", "species_10087880" ], "modifiers": [ [ "species_10087871", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087885": { "compartment": "compartment_70101", "id": "reaction_10087885", "reactome": "R-BTA-8951766", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087869", "species_10087850" ], "products": [ "species_10087871" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087852": { "compartment": "compartment_70101", "id": "reaction_10087852", "reactome": "R-BTA-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087845", "species_113592", "species_10075935" ], "products": [ "species_111294", "species_10087850", "species_76577" ], "modifiers": [], "additional_components": [ "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10088734": { "compartment": "compartment_7660", "id": "reaction_10088734", "reactome": "R-BTA-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088730", "species_10088728" ], "products": [ "species_10088732" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10087825": { "compartment": "compartment_70101", "id": "reaction_10087825", "reactome": "R-BTA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075937" ], "products": [ "species_10075927", "species_10075935" ], "modifiers": [], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000079440", "ENSBTAT00000028591" ] }, "reaction_10088688": { "compartment": "compartment_70101", "id": "reaction_10088688", "reactome": "R-BTA-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10088684" ], "products": [ "species_10088686" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10088787": { "compartment": "compartment_70101", "id": "reaction_10088787", "reactome": "R-BTA-8956026", "name": "CUL9:RBX1 ubiquitinates BIRC5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10088761" ], "products": [ "species_10088764" ], "modifiers": [ [ "species_10088774", "catalyst" ], [ "species_10088785", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018046", "ENSBTAT00000018046", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591", "F6R7X9", "ENSBTAT00000024194", "E1BK00", "ENSBTAT00000061262", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591" ] }, "reaction_10088807": { "compartment": "compartment_70101", "id": "reaction_10088807", "reactome": "R-BTA-8956040", "name": "COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088802" ], "products": [ "species_10088804", "species_10075935" ], "modifiers": [ [ "species_10084815", "catalyst" ] ], "additional_components": [ "A0A3Q1MTL8", "ENSBTAT00000087337", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MXH0", "ENSBTAT00000068692", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "ENSBTAT00000028591", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10075942": { "compartment": "compartment_70101", "id": "reaction_10075942", "reactome": "R-BTA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075933" ], "products": [ "species_10075939", "species_10075937" ], "modifiers": [ [ "species_10075933", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440" ] }, "reaction_10038457": { "compartment": "compartment_70101", "id": "reaction_10038457", "reactome": "R-BTA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10038454", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017653" ] }, "reaction_10038464": { "compartment": "compartment_12045", "id": "reaction_10038464", "reactome": "R-BTA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10038461", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012921" ] }, "reaction_10052665": { "compartment": "compartment_17963", "id": "reaction_10052665", "reactome": "R-BTA-914012", "name": "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052629" ], "products": [ "species_10052652", "species_205687" ], "modifiers": [ [ "species_10052662", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "Q7YQE1", "ENSBTAT00000079217", "A0A3Q1MUB2", "ENSBTAT00000076540" ] }, "reaction_10052521": { "compartment": "compartment_17963", "id": "reaction_10052521", "reactome": "R-BTA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052519", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382" ] }, "reaction_10077688": { "compartment": "compartment_20699", "id": "reaction_10077688", "reactome": "R-BTA-6786012", "name": "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10052652" ], "products": [ "species_742343", "species_10077681" ], "modifiers": [ [ "species_10077685", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "ENSBTAT00000022569" ] }, "reaction_10052461": { "compartment": "compartment_20699", "id": "reaction_10052461", "reactome": "R-BTA-913675", "name": "GALNTs transfer GalNAc from UDP-GalNAc to mucins to form Tn antigens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052377" ], "products": [ "species_10052400", "species_205687" ], "modifiers": [ [ "species_10052458", "catalyst" ] ], "additional_components": [ "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1MQ00", "ENSBTAT00000071740", "A0A3Q1M986", "ENSBTAT00000078875", "E1BPR6", "ENSBTAT00000061536", "E1BDW8", "ENSBTAT00000028329", "E1BBP1", "ENSBTAT00000018541", "E1BHN6", "ENSBTAT00000010847", "A6QLX6", "ENSBTAT00000077005", "E1BKQ9", "ENSBTAT00000023104", "Q07537", "ENSBTAT00000081582", "A0A3Q1LM69", "ENSBTAT00000087139", "F6QA59", "ENSBTAT00000023106" ] }, "reaction_10052716": { "compartment": "compartment_20699", "id": "reaction_10052716", "reactome": "R-BTA-914018", "name": "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052569" ], "products": [ "species_205687", "species_10052713" ], "modifiers": [ [ "species_10052656", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000079217" ] }, "reaction_10052606": { "compartment": "compartment_20699", "id": "reaction_10052606", "reactome": "R-BTA-914010", "name": "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_205687", "species_10052569" ], "modifiers": [ [ "species_10052603", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1MPZ8", "ENSBTAT00000078680", "A7YY64", "ENSBTAT00000024024", "F1MGN7", "ENSBTAT00000063600", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494", "Q0VC83", "ENSBTAT00000021344" ] }, "reaction_10054575": { "compartment": "compartment_20699", "id": "reaction_10054575", "reactome": "R-BTA-977228", "name": "Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000083430" ] }, "reaction_10054766": { "compartment": "compartment_20699", "id": "reaction_10054766", "reactome": "R-BTA-981809", "name": "ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10054701" ], "products": [ "species_10054759", "species_727810" ], "modifiers": [ [ "species_10054763", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "ENSBTAT00000063122" ] }, "reaction_10054722": { "compartment": "compartment_20699", "id": "reaction_10054722", "reactome": "R-BTA-981497", "name": "ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054701" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10054773": { "compartment": "compartment_17963", "id": "reaction_10054773", "reactome": "R-BTA-981814", "name": "GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054770", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000078008" ] }, "reaction_10054550": { "compartment": "compartment_17963", "id": "reaction_10054550", "reactome": "R-BTA-977071", "name": "Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052400" ], "products": [ "species_10054548", "species_727810" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "ENSBTAT00000083430" ] }, "reaction_10052496": { "compartment": "compartment_17963", "id": "reaction_10052496", "reactome": "R-BTA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052494", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675" ] }, "reaction_10061538": { "compartment": "compartment_20699", "id": "reaction_10061538", "reactome": "R-BTA-1964505", "name": "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052629", "species_205687" ], "modifiers": [ [ "species_10061535", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "Q0VC84", "ENSBTAT00000068688", "Q3SX46", "ENSBTAT00000028542" ] }, "reaction_10052546": { "compartment": "compartment_17963", "id": "reaction_10052546", "reactome": "R-BTA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052544", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10052690": { "compartment": "compartment_17963", "id": "reaction_10052690", "reactome": "R-BTA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052400" ], "products": [ "species_10052688", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10076773": { "compartment": "compartment_20699", "id": "reaction_10076773", "reactome": "R-BTA-5694487", "name": "A4GNT transfers GlcNAc to core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052652" ], "products": [ "species_10076766", "species_205687" ], "modifiers": [ [ "species_10076770", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000001899" ] }, "reaction_10070145": { "compartment": "compartment_12045", "id": "reaction_10070145", "reactome": "R-BTA-5173005", "name": "B3GALTL transfers glucose to O-fucosyl-proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070064", "species_173594" ], "products": [ "species_158602", "species_10070138" ], "modifiers": [ [ "species_10070142", "catalyst" ] ], "additional_components": [ "F1MXR3", "ENSBTAT00000081541", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BK41", "ENSBTAT00000061071", "E1BK41", "ENSBTAT00000061071", "F1MXR3", "ENSBTAT00000081541", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "ENSBTAT00000047526" ] }, "reaction_10077897": { "compartment": "compartment_70101", "id": "reaction_10077897", "reactome": "R-BTA-6788855", "name": "FN3KRP phosphorylates PsiAm, RibAm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788865" ], "products": [ "species_6788858", "species_29370" ], "modifiers": [ [ "species_10077894", "catalyst" ] ], "additional_components": [ "CHEBI:87176", "CHEBI:87177", "CHEBI:87180", "CHEBI:87179", "ENSBTAT00000020456" ] }, "reaction_10077883": { "compartment": "compartment_12045", "id": "reaction_10077883", "reactome": "R-BTA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10077880", "catalyst" ] ], "additional_components": [ "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10038408": { "compartment": "compartment_13959", "id": "reaction_10038408", "reactome": "R-BTA-159757", "name": "Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038406" ], "products": [ "species_10038394" ], "modifiers": [], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10038416": { "compartment": "compartment_13959", "id": "reaction_10038416", "reactome": "R-BTA-159783", "name": "Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038412" ], "products": [ "species_10038414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009746", "ENSBTAT00000009746" ] }, "reaction_10038438": { "compartment": "compartment_13959", "id": "reaction_10038438", "reactome": "R-BTA-159843", "name": "Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038436" ], "products": [ "species_10038384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406" ] }, "reaction_10043698": { "compartment": "compartment_70101", "id": "reaction_10043698", "reactome": "R-BTA-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_204628", "species_73473" ], "products": [ "species_204635", "species_29360", "species_10043689" ], "modifiers": [ [ "species_10043695", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ6", "ENSBTAT00000008200" ] }, "reaction_10043717": { "compartment": "compartment_70101", "id": "reaction_10043717", "reactome": "R-BTA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10043708", "species_29360" ], "modifiers": [ [ "species_10043714", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q0VC53", "ENSBTAT00000006935", "species_71067" ] }, "reaction_10060109": { "compartment": "compartment_17957", "id": "reaction_10060109", "reactome": "R-BTA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194653", "species_10060079" ], "products": [ "species_1663154", "species_194697", "species_10060106" ], "modifiers": [ [ "species_10060045", "catalyst" ] ], "additional_components": [ "F1N665", "ENSBTAT00000014061", "Q148F3", "ENSBTAT00000026877", "A0A3Q1LZ44", "ENSBTAT00000081469", "A6QLZ3", "ENSBTAT00000010988", "G3N2T7", "ENSBTAT00000072310", "A0A3Q1LGQ6", "ENSBTAT00000080500", "E1BIN3", "ENSBTAT00000017050", "A5D7J7", "ENSBTAT00000050377", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LZ44", "ENSBTAT00000081469", "F1N665", "ENSBTAT00000014061", "G3N2T7", "ENSBTAT00000072310", "A6QLZ3", "ENSBTAT00000010988", "E1BIN3", "ENSBTAT00000017050", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LGQ6", "ENSBTAT00000080500", "A5D7J7", "ENSBTAT00000050377", "Q148F3", "ENSBTAT00000026877", "ENSBTAT00000055237" ] }, "reaction_10091630": { "compartment": "compartment_17963", "id": "reaction_10091630", "reactome": "R-BTA-9668023", "name": "TPST1,2 transfer SO4(2-) from PAPS to FVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091620", "species_741440" ], "products": [ "species_742343", "species_10091628" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036726", "ENSBTAT00000036726", "ENSBTAT00000000502" ] }, "reaction_10071579": { "compartment": "compartment_70101", "id": "reaction_10071579", "reactome": "R-BTA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071569", "species_71284" ], "products": [ "species_10071572", "species_71285" ], "modifiers": [ [ "species_10071576", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000025327" ] }, "reaction_10071566": { "compartment": "compartment_70101", "id": "reaction_10071566", "reactome": "R-BTA-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071559", "species_113592", "species_31633" ], "products": [ "species_111294", "species_10038103", "species_76577" ], "modifiers": [ [ "species_10071563", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000055382" ] }, "reaction_10066409": { "compartment": "compartment_7660", "id": "reaction_10066409", "reactome": "R-BTA-2993763", "name": "SENP1,2,5 proteolytically process SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066405" ], "products": [ "species_10066407" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023029", "ENSBTAT00000023029", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066380": { "compartment": "compartment_7660", "id": "reaction_10066380", "reactome": "R-BTA-2990842", "name": "SENP1,2,5 proteolytically process SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066376" ], "products": [ "species_10066378" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081472", "ENSBTAT00000081472", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066372": { "compartment": "compartment_7660", "id": "reaction_10066372", "reactome": "R-BTA-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066355" ], "products": [ "species_10051814" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10077406": { "compartment": "compartment_7660", "id": "reaction_10077406", "reactome": "R-BTA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056739", "species_10077402" ], "products": [ "species_10077404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055368", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "Q2TA10", "ENSBTAT00000055368" ] }, "reaction_10076001": { "compartment": "compartment_70101", "id": "reaction_10076001", "reactome": "R-BTA-5690870", "name": "OTUD7B,TNFAIP3 deubiquitinate TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075996" ], "products": [ "species_10052288", "species_10075998" ], "modifiers": [ [ "species_10075996", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10085345": { "compartment": "compartment_70101", "id": "reaction_10085345", "reactome": "R-BTA-8869506", "name": "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10085342" ], "products": [ "species_10039539", "species_10075998" ], "modifiers": [ [ "species_10085342", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075952": { "compartment": "compartment_70101", "id": "reaction_10075952", "reactome": "R-BTA-5690827", "name": "TNFAIP3 (A20) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10075944" ], "products": [ "species_10075949" ], "modifiers": [ [ "species_10075944", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075984": { "compartment": "compartment_70101", "id": "reaction_10075984", "reactome": "R-BTA-5690845", "name": "TNIPs bind TNFAIP3 (A20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037956", "species_10075980" ], "products": [ "species_10075982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069028", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10084931": { "compartment": "compartment_70101", "id": "reaction_10084931", "reactome": "R-BTA-8865182", "name": "OTUD7A hydrolyses K11diUb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075838" ], "products": [ "species_10033408" ], "modifiers": [ [ "species_10084928", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000009023" ] }, "reaction_10075970": { "compartment": "compartment_70101", "id": "reaction_10075970", "reactome": "R-BTA-5690843", "name": "OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075966", "species_10075962" ], "products": [ "species_10075968" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600" ] }, "reaction_10075989": { "compartment": "compartment_70101", "id": "reaction_10075989", "reactome": "R-BTA-5690856", "name": "TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075986" ], "products": [ "species_10039539", "species_10075944" ], "modifiers": [ [ "species_10075986", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10077371": { "compartment": "compartment_70101", "id": "reaction_10077371", "reactome": "R-BTA-6781899", "name": "USP13 binds SIAH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077367", "species_10054896" ], "products": [ "species_10077369" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061390", "ENSBTAT00000044404", "F1MBM6", "ENSBTAT00000044404", "E1BMF7", "ENSBTAT00000061390" ] }, "reaction_10077339": { "compartment": "compartment_70101", "id": "reaction_10077339", "reactome": "R-BTA-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077335", "species_10071514" ], "products": [ "species_10077337" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025198", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10075550": { "compartment": "compartment_7660", "id": "reaction_10075550", "reactome": "R-BTA-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075418" ], "products": [ "species_10075422", "species_10075547" ], "modifiers": [ [ "species_10075418", "catalyst" ] ], "additional_components": [ "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418", "F1N556", "ENSBTAT00000007177", "A6QLP0", "ENSBTAT00000006418", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10075902": { "compartment": "compartment_7660", "id": "reaction_10075902", "reactome": "R-BTA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075897" ], "products": [ "species_10036828", "species_10075899" ], "modifiers": [ [ "species_10075897", "catalyst" ] ], "additional_components": [ "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1MY85", "ENSBTAT00000087113" ] }, "reaction_10077393": { "compartment": "compartment_7660", "id": "reaction_10077393", "reactome": "R-BTA-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077388" ], "products": [ "species_10075488", "species_10077390" ], "modifiers": [ [ "species_10077388", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075891": { "compartment": "compartment_70101", "id": "reaction_10075891", "reactome": "R-BTA-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075886" ], "products": [ "species_10033408", "species_10075888" ], "modifiers": [ [ "species_10075886", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356" ] }, "reaction_10077363": { "compartment": "compartment_70101", "id": "reaction_10077363", "reactome": "R-BTA-6781897", "name": "USP11 deubiquitinates NFKBIA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077358" ], "products": [ "species_10077360", "species_10075884" ], "modifiers": [ [ "species_10077358", "catalyst" ] ], "additional_components": [ "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10077331": { "compartment": "compartment_7660", "id": "reaction_10077331", "reactome": "R-BTA-5696958", "name": "USP44 deubiquitinates CDC20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077326" ], "products": [ "species_10077328", "species_10075547" ], "modifiers": [ [ "species_10077326", "catalyst" ] ], "additional_components": [ "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571" ] }, "reaction_10075561": { "compartment": "compartment_7660", "id": "reaction_10075561", "reactome": "R-BTA-5689973", "name": "USP10,USP24,USP42 deubiquitinate TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075556" ], "products": [ "species_10075558", "species_10075547" ], "modifiers": [ [ "species_10075556", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967", "A0A452DHT6", "ENSBTAT00000000967", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967" ] }, "reaction_10077034": { "compartment": "compartment_70101", "id": "reaction_10077034", "reactome": "R-BTA-5696564", "name": "USP25 deubiquitinates DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077029" ], "products": [ "species_10077031", "species_10075884" ], "modifiers": [ [ "species_10077029", "catalyst" ] ], "additional_components": [ "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MMX0", "ENSBTAT00000075352", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10077292": { "compartment": "compartment_17906", "id": "reaction_10077292", "reactome": "R-BTA-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077171" ], "products": [ "species_10077189", "species_10077289" ], "modifiers": [ [ "species_10077171", "catalyst" ] ], "additional_components": [ "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733" ] }, "reaction_10077070": { "compartment": "compartment_70101", "id": "reaction_10077070", "reactome": "R-BTA-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077061" ], "products": [ "species_10075884", "species_10077067" ], "modifiers": [ [ "species_10077061", "catalyst" ] ], "additional_components": [ "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MKU1", "ENSBTAT00000061377", "E1BJZ0", "ENSBTAT00000010703", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075808": { "compartment": "compartment_7660", "id": "reaction_10075808", "reactome": "R-BTA-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075801" ], "products": [ "species_10036828", "species_10075805" ], "modifiers": [ [ "species_10075801", "catalyst" ] ], "additional_components": [ "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438" ] }, "reaction_10077379": { "compartment": "compartment_7660", "id": "reaction_10077379", "reactome": "R-BTA-6781922", "name": "USP13 binds UFD1L:SKP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077375", "species_10077373" ], "products": [ "species_10077377" ], "modifiers": [], "additional_components": [ "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000061390", "E1BMF7", "ENSBTAT00000061390", "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10077349": { "compartment": "compartment_70101", "id": "reaction_10077349", "reactome": "R-BTA-6781814", "name": "USP19 deubiquitinates RNF123", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077344" ], "products": [ "species_10077346", "species_10039539" ], "modifiers": [ [ "species_10077344", "catalyst" ] ], "additional_components": [ "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10077317": { "compartment": "compartment_7660", "id": "reaction_10077317", "reactome": "R-BTA-5696914", "name": "USP28 deubiquitinates CLSPN and MYC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077308" ], "products": [ "species_10077314", "species_10075547" ], "modifiers": [ [ "species_10077308", "catalyst" ] ], "additional_components": [ "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1LF69", "ENSBTAT00000074281", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720" ] }, "reaction_10075374": { "compartment": "compartment_7660", "id": "reaction_10075374", "reactome": "R-BTA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10075370" ], "products": [ "species_10075372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10075397": { "compartment": "compartment_70101", "id": "reaction_10075397", "reactome": "R-BTA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039539" ], "products": [ "species_10039539", "species_10039537" ], "modifiers": [ [ "species_10075394", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MF75", "ENSBTAT00000067648", "A6H799", "ENSBTAT00000007611", "A0A3Q1M4J1", "ENSBTAT00000073722", "F1ME39", "ENSBTAT00000008984" ] }, "reaction_10086303": { "compartment": "compartment_7660", "id": "reaction_10086303", "reactome": "R-BTA-8932275", "name": "METTL22 transfers 3xCH3 from 3xAdoMet to KIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086293" ], "products": [ "species_77502", "species_10086296" ], "modifiers": [ [ "species_10086300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061405", "ENSBTAT00000061405", "ENSBTAT00000084035" ] }, "reaction_10086319": { "compartment": "compartment_70101", "id": "reaction_10086319", "reactome": "R-BTA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_71285", "species_10086312" ], "modifiers": [ [ "species_10086316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000085737" ] }, "reaction_10086286": { "compartment": "compartment_70101", "id": "reaction_10086286", "reactome": "R-BTA-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_10086279", "species_71285" ], "modifiers": [ [ "species_10086283", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000065836" ] }, "reaction_10077744": { "compartment": "compartment_70101", "id": "reaction_10077744", "reactome": "R-BTA-6786205", "name": "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10037000" ], "products": [ "species_71285", "species_10077737" ], "modifiers": [ [ "species_10077741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044622", "ENSBTAT00000044622", "ENSBTAT00000046124" ] }, "reaction_10083231": { "compartment": "compartment_70101", "id": "reaction_10083231", "reactome": "R-BTA-6814418", "name": "PDCL promotes formation of G-beta:G-gamma heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037407", "species_10083225" ], "products": [ "species_10083229" ], "modifiers": [], "additional_components": [ "P63212", "ENSBTAT00000003959", "Q2HJA9", "ENSBTAT00000043370", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648" ] }, "reaction_10083808": { "compartment": "compartment_70101", "id": "reaction_10083808", "reactome": "R-BTA-8850560", "name": "G-protein alpha releases G-protein heterotrimer from PDCL ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083229", "species_10036952" ], "products": [ "species_10083806", "species_10083195" ], "modifiers": [], "additional_components": [ "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "ENSBTAT00000043370" ] }, "reaction_10077947": { "compartment": "compartment_3828046", "id": "reaction_10077947", "reactome": "R-BTA-6791016", "name": "SFTPB binds itself", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074840" ], "products": [ "species_10074859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "P15781", "ENSBTAT00000045134" ] }, "reaction_10088922": { "compartment": "compartment_12045", "id": "reaction_10088922", "reactome": "R-BTA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088918" ], "products": [ "species_10088920" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074686": { "compartment": "compartment_2133233", "id": "reaction_10074686", "reactome": "R-BTA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10074683", "catalyst" ] ], "additional_components": [ "species_429785", "species_1602402", "species_429785", "species_1602402", "ENSBTAT00000019840" ] }, "reaction_10074833": { "compartment": "compartment_80738", "id": "reaction_10074833", "reactome": "R-BTA-5684862", "name": "SFTPB,C, PC, PG translocate from lamellar body to extracellular region.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074821", "species_10074817", "species_5684869" ], "products": [ "species_5686242", "species_10074827", "species_10074825" ], "modifiers": [ [ "species_10048001", "catalyst" ], [ "species_10046205", "catalyst" ], [ "species_10074831", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_429785", "species_1602402", "species_1602402", "species_429785", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "ENSBTAT00000035930" ] }, "reaction_10091120": { "compartment": "compartment_12045", "id": "reaction_10091120", "reactome": "R-BTA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088920" ], "products": [ "species_10075101" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074707": { "compartment": "compartment_7660", "id": "reaction_10074707", "reactome": "R-BTA-5683831", "name": "CCDC59 binds TTF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074703", "species_10074699" ], "products": [ "species_10074705" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024905", "ENSBTAT00000050784", "A5PJN1", "ENSBTAT00000050784", "E1B9V4", "ENSBTAT00000024905" ] }, "reaction_10074869": { "compartment": "compartment_12045", "id": "reaction_10074869", "reactome": "R-BTA-5684868", "name": "pro-SFTPC translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074865" ], "products": [ "species_10074867" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672" ] }, "reaction_10075125": { "compartment": "compartment_876", "id": "reaction_10075125", "reactome": "R-BTA-5686359", "name": "SFTPs translocate from extracellular region to clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075103" ], "products": [ "species_10075111", "species_10075123", "species_10075117", "species_10075099", "species_10075115" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134" ] }, "reaction_10091124": { "compartment": "compartment_12045", "id": "reaction_10091124", "reactome": "R-BTA-9624789", "name": "pro-SFTPB translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091122" ], "products": [ "species_10074838" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134" ] }, "reaction_10075095": { "compartment": "compartment_876", "id": "reaction_10075095", "reactome": "R-BTA-5686304", "name": "ZDHHC2 transfers PALM from PALM-CoA to CKAP4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075088", "species_200993" ], "products": [ "species_10075070", "species_76194" ], "modifiers": [ [ "species_10075092", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015804", "ENSBTAT00000015804", "ENSBTAT00000064000" ] }, "reaction_10074857": { "compartment": "compartment_3828046", "id": "reaction_10074857", "reactome": "R-BTA-5684864", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074838", "species_5685882" ], "products": [ "species_10074844", "species_10074842", "species_10074840" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10075019": { "compartment": "compartment_12045", "id": "reaction_10075019", "reactome": "R-BTA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075015" ], "products": [ "species_10075017" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075084": { "compartment": "compartment_876", "id": "reaction_10075084", "reactome": "R-BTA-5686286", "name": "PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075072" ], "products": [ "species_10075082" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804", "F1ME65", "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075023": { "compartment": "compartment_3828046", "id": "reaction_10075023", "reactome": "R-BTA-5685902", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5685882", "species_10074867" ], "products": [ "species_10075021", "species_10074861" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672", "ENSBTAT00000016672", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10074863": { "compartment": "compartment_3828046", "id": "reaction_10074863", "reactome": "R-BTA-5684865", "name": "SFTPB dimer,C translocate from multivesicle body to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074861", "species_10074859" ], "products": [ "species_10074821", "species_10074817" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134" ] }, "reaction_10075086": { "compartment": "compartment_876", "id": "reaction_10075086", "reactome": "R-BTA-5686301", "name": "PALM-C100-CKAP4 binds SFTPAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075070", "species_10075017" ], "products": [ "species_10075072" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804" ] }, "reaction_10075105": { "compartment": "compartment_876", "id": "reaction_10075105", "reactome": "R-BTA-5686335", "name": "CSF2RA:CSF2RB binds SFTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075101", "species_10074827", "species_10075099", "species_10074825", "species_10075017" ], "products": [ "species_10075103" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579" ] }, "reaction_10081291": { "compartment": "compartment_70101", "id": "reaction_10081291", "reactome": "R-BTA-6800797", "name": "The PIDDosome activates CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081288" ], "products": [ "species_10081284", "species_10043771", "species_10043769" ], "modifiers": [ [ "species_10081288", "catalyst" ] ], "additional_components": [ "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "ENSBTAT00000071790", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081274": { "compartment": "compartment_7660", "id": "reaction_10081274", "reactome": "R-BTA-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10081269" ], "products": [ "species_113582", "species_10081272" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157", "ENSBTAT00000040104" ] }, "reaction_10081293": { "compartment": "compartment_70101", "id": "reaction_10081293", "reactome": "R-BTA-6800798", "name": "The PIDDosome binds CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043767", "species_10081284" ], "products": [ "species_10081288" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081278": { "compartment": "compartment_70101", "id": "reaction_10081278", "reactome": "R-BTA-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081272" ], "products": [ "species_10081276" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157" ] }, "reaction_10081286": { "compartment": "compartment_70101", "id": "reaction_10081286", "reactome": "R-BTA-6800794", "name": "PIDD1 associates with CRADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081282", "species_10081276" ], "products": [ "species_10081284" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071531", "ENSBTAT00000026157", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531" ] }, "reaction_10080457": { "compartment": "compartment_7660", "id": "reaction_10080457", "reactome": "R-BTA-6799097", "name": "ATM phosphorylates ZNF420", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10053725" ], "products": [ "species_113582", "species_10080455" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "A0A3Q1ML53", "ENSBTAT00000083153", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "A0A3Q1ML53", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "ENSBTAT00000040104" ] }, "reaction_10081305": { "compartment": "compartment_74700", "id": "reaction_10081305", "reactome": "R-BTA-6801195", "name": "STEAP3 binds BNIP3L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081301", "species_10052892" ], "products": [ "species_10081303" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033862", "ENSBTAT00000077862", "A0A3Q1LPT9", "ENSBTAT00000077862", "Q3T013", "ENSBTAT00000033862" ] }, "reaction_10081323": { "compartment": "compartment_17927", "id": "reaction_10081323", "reactome": "R-BTA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081319", "species_10081309" ], "products": [ "species_10081321" ], "modifiers": [], "additional_components": [ "Q32KN9", "ENSBTAT00000006594", "ENSBTAT00000016994", "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10081326": { "compartment": "compartment_17906", "id": "reaction_10081326", "reactome": "R-BTA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10081321", "catalyst" ] ], "additional_components": [ "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10080738": { "compartment": "compartment_70101", "id": "reaction_10080738", "reactome": "R-BTA-6799466", "name": "TP53I3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080734" ], "products": [ "species_10080736" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004413", "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10080789": { "compartment": "compartment_70101", "id": "reaction_10080789", "reactome": "R-BTA-6799722", "name": "TP53I3 oxidoreductase generates unstable semiquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6799725", "species_29364" ], "products": [ "species_6799726", "species_29366" ], "modifiers": [ [ "species_10080736", "catalyst" ] ], "additional_components": [ "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10056702": { "compartment": "compartment_70101", "id": "reaction_10056702", "reactome": "R-BTA-1234164", "name": "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056667" ], "products": [ "species_29434", "species_10056691", "species_113528" ], "modifiers": [ [ "species_10056699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075132", "ENSBTAT00000075132", "species_198836", "species_71067", "F1MG82", "ENSBTAT00000000101" ] }, "reaction_10056679": { "compartment": "compartment_70101", "id": "reaction_10056679", "reactome": "R-BTA-1234161", "name": "HIF-alpha translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056671" ], "products": [ "species_10056677" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056761": { "compartment": "compartment_70101", "id": "reaction_10056761", "reactome": "R-BTA-1234183", "name": "Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056629", "species_10056659" ], "products": [ "species_10056685" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056719": { "compartment": "compartment_7660", "id": "reaction_10056719", "reactome": "R-BTA-1234165", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056675", "species_113671", "species_113685" ], "products": [ "species_10056704", "species_159942", "species_159939" ], "modifiers": [ [ "species_10056716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_71067", "A0A3Q1LUX2", "ENSBTAT00000072600", "species_198836", "A7MBA0", "ENSBTAT00000010744" ] }, "reaction_10056737": { "compartment": "compartment_7660", "id": "reaction_10056737", "reactome": "R-BTA-1234169", "name": "Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056723", "species_10056733" ], "products": [ "species_10056735" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056688": { "compartment": "compartment_70101", "id": "reaction_10056688", "reactome": "R-BTA-1234163", "name": "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056685", "species_10056683" ], "products": [ "species_10056661", "species_10056681" ], "modifiers": [ [ "species_10056685", "catalyst" ] ], "additional_components": [ "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056754": { "compartment": "compartment_7660", "id": "reaction_10056754", "reactome": "R-BTA-1234172", "name": "Nuclear VBC complex ubiquitinylates HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056735", "species_10056747" ], "products": [ "species_10056751", "species_10056745" ], "modifiers": [ [ "species_10056735", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056757": { "compartment": "compartment_70101", "id": "reaction_10056757", "reactome": "R-BTA-1234173", "name": "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056669" ], "products": [ "species_29434", "species_10056627", "species_113528" ], "modifiers": [ [ "species_10056659", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10056759": { "compartment": "compartment_70101", "id": "reaction_10056759", "reactome": "R-BTA-1234175", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056751" ], "products": [ "species_10056633" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10044776": { "compartment": "compartment_70101", "id": "reaction_10044776", "reactome": "R-BTA-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044772", "species_10033775" ], "products": [ "species_10044774" ], "modifiers": [], "additional_components": [ "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000005575", "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044794": { "compartment": "compartment_70101", "id": "reaction_10044794", "reactome": "R-BTA-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044774", "species_10044788" ], "products": [ "species_10044792" ], "modifiers": [], "additional_components": [ "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000072826", "P27117", "ENSBTAT00000005575", "A3KMV9", "ENSBTAT00000072826", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044784": { "compartment": "compartment_70101", "id": "reaction_10044784", "reactome": "R-BTA-350578", "name": "NQO1 interaction with ODC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033775", "species_10044780" ], "products": [ "species_10044782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005575", "ENSBTAT00000079752", "A0A3Q1MK02", "ENSBTAT00000079752", "P27117", "ENSBTAT00000005575" ] }, "reaction_10047519": { "compartment": "compartment_70101", "id": "reaction_10047519", "reactome": "R-BTA-392513", "name": "Rap1 signal termination by Rap1GAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045005" ], "products": [ "species_111294", "species_10045007" ], "modifiers": [ [ "species_10047512", "catalyst" ], [ "species_10047517", "inhibitor" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "A0A3Q1MI55", "ENSBTAT00000066483", "A0A3Q1MTG9", "ENSBTAT00000077316", "A0A3Q1LME0", "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439" ] }, "reaction_10047536": { "compartment": "compartment_70101", "id": "reaction_10047536", "reactome": "R-BTA-392834", "name": "Activation of EPACs by cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10047532" ], "products": [ "species_10047534" ], "modifiers": [], "additional_components": [ "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389" ] }, "reaction_10052466": { "compartment": "compartment_70101", "id": "reaction_10052466", "reactome": "R-BTA-913993", "name": "14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_10047515" ], "products": [ "species_10047517" ], "modifiers": [ [ "species_10052464", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439", "ENSBTAT00000075439" ] }, "reaction_10052471": { "compartment": "compartment_70101", "id": "reaction_10052471", "reactome": "R-BTA-913996", "name": "PKA/PKG phosphorylate Rap1GAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_113592" ], "products": [ "species_29370", "species_10052464" ], "modifiers": [ [ "species_427893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075439", "ENSBTAT00000075439", "ENSBTAT00000030539" ] }, "reaction_10071800": { "compartment": "compartment_70101", "id": "reaction_10071800", "reactome": "R-BTA-5577050", "name": "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071797", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1LPA7", "ENSBTAT00000069177" ] }, "reaction_10059961": { "compartment": "compartment_70101", "id": "reaction_10059961", "reactome": "R-BTA-1605723", "name": "Neu5Ac is cleaved from GM3 by NEU2 to form a globoside (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605590", "species_29356" ], "products": [ "species_428633", "species_1605647" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027552" ] }, "reaction_10071483": { "compartment": "compartment_70101", "id": "reaction_10071483", "reactome": "R-BTA-5339535", "name": "GLTPD1 transports C1P from plasma membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1638840" ], "products": [ "species_5339515" ], "modifiers": [ [ "species_10071480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010025" ] }, "reaction_10084410": { "compartment": "compartment_20699", "id": "reaction_10084410", "reactome": "R-BTA-8856223", "name": "B4GALNT1 dimer transfers GalNAc from UDP-GalNAc to GM3 and GD3 gangliosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_8856243" ], "products": [ "species_8856242", "species_205687" ], "modifiers": [ [ "species_10084407", "catalyst" ] ], "additional_components": [ "species_1605641", "CHEBI:28424", "species_1605610", "CHEBI:28648", "Q58DI2", "ENSBTAT00000005893" ] }, "reaction_10060316": { "compartment": "compartment_876", "id": "reaction_10060316", "reactome": "R-BTA-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060313", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002552" ] }, "reaction_10059984": { "compartment": "compartment_70101", "id": "reaction_10059984", "reactome": "R-BTA-1605768", "name": "Neu5Ac is cleaved from GM3 by NEU3 to form globoside (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1605649" ], "products": [ "species_428633", "species_1605618" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036738" ] }, "reaction_10059954": { "compartment": "compartment_161320", "id": "reaction_10059954", "reactome": "R-BTA-1605717", "name": "Ganglioside GM2 activator presents GM2 to hexosaminidase for cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059927", "species_1605610" ], "products": [ "species_10059929" ], "modifiers": [ [ "species_10059927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029099", "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099" ] }, "reaction_10060021": { "compartment": "compartment_876", "id": "reaction_10060021", "reactome": "R-BTA-1606583", "name": "Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429807" ], "products": [ "species_1606609", "species_1861754" ], "modifiers": [ [ "species_10060018", "catalyst" ] ], "additional_components": [] }, "reaction_10060309": { "compartment": "compartment_876", "id": "reaction_10060309", "reactome": "R-BTA-1638845", "name": "CERK phosphorylates CERA to form C1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429807", "species_113592" ], "products": [ "species_29370", "species_1638840" ], "modifiers": [ [ "species_10060306", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064397" ] }, "reaction_10059991": { "compartment": "compartment_161320", "id": "reaction_10059991", "reactome": "R-BTA-1605797", "name": "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605713" ], "products": [ "species_1605750", "species_1605673" ], "modifiers": [ [ "species_10059988", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020758" ] }, "reaction_10059977": { "compartment": "compartment_161320", "id": "reaction_10059977", "reactome": "R-BTA-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605637", "species_1605601" ], "modifiers": [ [ "species_10059974", "catalyst" ] ], "additional_components": [ "E1B725", "ENSBTAT00000025636" ] }, "reaction_10060041": { "compartment": "compartment_12045", "id": "reaction_10060041", "reactome": "R-BTA-1606839", "name": "Steryl sulfatase hydrolyses sulfate from steroid sulfates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_1609648" ], "products": [ "species_1609650", "species_1609649" ], "modifiers": [ [ "species_10060038", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LZ44", "ENSBTAT00000081469" ] }, "reaction_10071497": { "compartment": "compartment_876", "id": "reaction_10071497", "reactome": "R-BTA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10071494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003355" ] }, "reaction_10059944": { "compartment": "compartment_161320", "id": "reaction_10059944", "reactome": "R-BTA-1605595", "name": "Hexosaminidase A cleaves GalNAc from GM2 to form GM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10059929" ], "products": [ "species_10059927", "species_1605658", "species_1605641" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099", "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060012": { "compartment": "compartment_876", "id": "reaction_10060012", "reactome": "R-BTA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060009", "catalyst" ] ], "additional_components": [ "species_29926", "F1N588", "ENSBTAT00000010706" ] }, "reaction_10059951": { "compartment": "compartment_161320", "id": "reaction_10059951", "reactome": "R-BTA-1605632", "name": "Both hexosaminidase A and B can cleave GalNAc from globoside", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605608" ], "products": [ "species_1605716", "species_1605658" ], "modifiers": [ [ "species_10059948", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411", "Q0V8R6", "ENSBTAT00000017261" ] }, "reaction_10060302": { "compartment": "compartment_20699", "id": "reaction_10060302", "reactome": "R-BTA-1638104", "name": "Ceramide glucosyltransferase (UGCG) catalyses the transfer of glucose to ceramide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744227", "species_428270" ], "products": [ "species_1660674", "species_205687" ], "modifiers": [ [ "species_10060299", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043826" ] }, "reaction_10059968": { "compartment": "compartment_161320", "id": "reaction_10059968", "reactome": "R-BTA-1605724", "name": "Neu5Ac is cleaved from GM3 by NEU1 and 4 to form a globoside (lysosomal lumen)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605641" ], "products": [ "species_1605601", "species_428639" ], "modifiers": [ [ "species_10059965", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019755" ] }, "reaction_10048986": { "compartment": "compartment_70101", "id": "reaction_10048986", "reactome": "R-BTA-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428671", "species_428686" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049116": { "compartment": "compartment_12045", "id": "reaction_10049116", "reactome": "R-BTA-429683", "name": "CERT:ceramide [ER] => ceramide [Golgi] + CERT [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049108" ], "products": [ "species_10049110", "species_428270" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000027095" ] }, "reaction_10048860": { "compartment": "compartment_70101", "id": "reaction_10048860", "reactome": "R-BTA-428127", "name": "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_9695889" ], "products": [ "species_113528", "species_76194", "species_428182" ], "modifiers": [ [ "species_10048843", "catalyst" ], [ "species_10048858", "inhibitor" ] ], "additional_components": [ "Q5E978", "ENSBTAT00000018578", "Q0IIK4", "ENSBTAT00000085219", "Q3MHG1", "ENSBTAT00000002872", "A5PKM3", "ENSBTAT00000027289", "Q0VD15", "ENSBTAT00000018402", "Q29RQ9", "ENSBTAT00000016673", "Q5E972", "ENSBTAT00000027540" ] }, "reaction_10048988": { "compartment": "compartment_70101", "id": "reaction_10048988", "reactome": "R-BTA-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049182": { "compartment": "compartment_876", "id": "reaction_10049182", "reactome": "R-BTA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10049179", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072919" ] }, "reaction_10048978": { "compartment": "compartment_70101", "id": "reaction_10048978", "reactome": "R-BTA-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428275" ], "products": [ "species_29372", "species_428694" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10048917": { "compartment": "compartment_70101", "id": "reaction_10048917", "reactome": "R-BTA-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9025544" ], "products": [ "species_428237", "species_3632878" ], "modifiers": [ [ "species_10048914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052101" ] }, "reaction_10049161": { "compartment": "compartment_70101", "id": "reaction_10049161", "reactome": "R-BTA-429730", "name": "multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049158", "species_29356" ], "products": [ "species_10049110", "species_29372" ], "modifiers": [ [ "species_10049158", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10049163": { "compartment": "compartment_70101", "id": "reaction_10049163", "reactome": "R-BTA-429732", "name": "multiphospho-CERT + PPM1L:VAPA/B => multiphospho-CERT:PPM1L:VAPA/B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049100", "species_10049147" ], "products": [ "species_10049158" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10082058": { "compartment": "compartment_13977", "id": "reaction_10082058", "reactome": "R-BTA-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6808468", "species_29360" ], "products": [ "species_2453691", "species_70106", "species_73473" ], "modifiers": [ [ "species_10082055", "catalyst" ] ], "additional_components": [ "A0A3Q1M3Q4", "ENSBTAT00000085198", "Q1JPA0", "ENSBTAT00000076578" ] }, "reaction_10048910": { "compartment": "compartment_70101", "id": "reaction_10048910", "reactome": "R-BTA-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428126", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9025544" ], "modifiers": [ [ "species_10048907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012243" ] }, "reaction_10048896": { "compartment": "compartment_70101", "id": "reaction_10048896", "reactome": "R-BTA-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428163" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10048893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074462" ] }, "reaction_10049154": { "compartment": "compartment_70101", "id": "reaction_10049154", "reactome": "R-BTA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049124", "species_113592" ], "products": [ "species_29370", "species_10049147" ], "modifiers": [ [ "species_10049151", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "ENSBTAT00000022345" ] }, "reaction_10048903": { "compartment": "compartment_70101", "id": "reaction_10048903", "reactome": "R-BTA-428231", "name": "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428256" ], "products": [ "species_428193", "species_428198" ], "modifiers": [ [ "species_10048900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010648" ] }, "reaction_10048889": { "compartment": "compartment_20699", "id": "reaction_10048889", "reactome": "R-BTA-428205", "name": "ceramide + H2O => stearate + sphingosine [Golgi]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428270" ], "products": [ "species_428248", "species_8934421" ], "modifiers": [ [ "species_10048886", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014354" ] }, "reaction_10048882": { "compartment": "compartment_70101", "id": "reaction_10048882", "reactome": "R-BTA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10048879", "catalyst" ] ], "additional_components": [ "A0A3Q1MVP2", "ENSBTAT00000082150", "A0A3Q1MJ30", "ENSBTAT00000080491", "A4FUG2", "ENSBTAT00000036524", "A5D7K4", "ENSBTAT00000052579" ] }, "reaction_10049141": { "compartment": "compartment_70101", "id": "reaction_10049141", "reactome": "R-BTA-429698", "name": "PRKD1,2,3 phosphorylates COL4A3BP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049119" ], "products": [ "species_10049124", "species_29370" ], "modifiers": [ [ "species_10049138", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "A0A3Q1N9F5", "ENSBTAT00000081006", "F1MIA2", "ENSBTAT00000020721", "E1B7L9", "ENSBTAT00000070039" ] }, "reaction_10049143": { "compartment": "compartment_12045", "id": "reaction_10049143", "reactome": "R-BTA-429699", "name": "CERT [ER] + ceramide [ER] => CERT:ceramide [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110", "species_428256" ], "products": [ "species_10049108" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10076151": { "compartment": "compartment_12045", "id": "reaction_10076151", "reactome": "R-BTA-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428671", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076148", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10049004": { "compartment": "compartment_70101", "id": "reaction_10049004", "reactome": "R-BTA-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10049001", "catalyst" ] ], "additional_components": [ "A0A3Q1MIK4", "ENSBTAT00000069794", "Q3SZE3", "ENSBTAT00000015460" ] }, "reaction_10049007": { "compartment": "compartment_70101", "id": "reaction_10049007", "reactome": "R-BTA-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10049121": { "compartment": "compartment_70101", "id": "reaction_10049121", "reactome": "R-BTA-429694", "name": "CERT:PPM1L:VAPA/B [ER] => CERT [cytosol] + PPM1L:VAPA/B [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110" ], "products": [ "species_10049119", "species_10049100" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250" ] }, "reaction_10076833": { "compartment": "compartment_876", "id": "reaction_10076833", "reactome": "R-BTA-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428663", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076830", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076578" ] }, "reaction_10091936": { "compartment": "compartment_70101", "id": "reaction_10091936", "reactome": "R-BTA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10091933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009765" ] }, "reaction_10048995": { "compartment": "compartment_984", "id": "reaction_10048995", "reactome": "R-BTA-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10048992", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069794" ] }, "reaction_10076389": { "compartment": "compartment_12045", "id": "reaction_10076389", "reactome": "R-BTA-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10076386", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016212" ] }, "reaction_10049189": { "compartment": "compartment_20699", "id": "reaction_10049189", "reactome": "R-BTA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10049186", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082007" ] }, "reaction_10091941": { "compartment": "compartment_70101", "id": "reaction_10091941", "reactome": "R-BTA-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_428203", "species_29370" ], "modifiers": [ [ "species_10048893", "catalyst" ], [ "species_10091939", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000074462", "A0A3Q1MBG6", "ENSBTAT00000074462" ] }, "reaction_10043933": { "compartment": "compartment_70101", "id": "reaction_10043933", "reactome": "R-BTA-209823", "name": "Tyrosine is hydroxylated to dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29368", "species_29506" ], "products": [ "species_209849", "species_71112" ], "modifiers": [ [ "species_10043930", "catalyst" ] ], "additional_components": [ "A0A3Q1MAN0", "ENSBTAT00000077835", "species_71067" ] }, "reaction_10073477": { "compartment": "compartment_5668572", "id": "reaction_10073477", "reactome": "R-BTA-5662660", "name": "Dopachrome is transformed to DHICA by DCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5662665" ], "products": [ "species_5662670" ], "modifiers": [ [ "species_10073474", "catalyst" ] ], "additional_components": [ "F1MC37", "ENSBTAT00000034881", "species_29426" ] }, "reaction_10044216": { "compartment": "compartment_17960", "id": "reaction_10044216", "reactome": "R-BTA-211924", "name": "CYP4B1 12-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215075" ], "modifiers": [ [ "species_10044213", "catalyst" ] ], "additional_components": [ "Q148E6", "ENSBTAT00000015892" ] }, "reaction_10044195": { "compartment": "compartment_17960", "id": "reaction_10044195", "reactome": "R-BTA-211904", "name": "CYP4F12 18-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_352318" ], "modifiers": [ [ "species_10044192", "catalyst" ] ], "additional_components": [ "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "A0A3Q1MCJ2", "ENSBTAT00000073532", "M0QW30", "ENSBTAT00000072981" ] }, "reaction_10044260": { "compartment": "compartment_17960", "id": "reaction_10044260", "reactome": "R-BTA-211983", "name": "CYP2J2 oxidises ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215062" ], "modifiers": [ [ "species_10044257", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34157", "species_2142739", "CHEBI:34490", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10035958": { "compartment": "compartment_17960", "id": "reaction_10035958", "reactome": "R-BTA-76466", "name": "CYP4A11 12-hydroxylates DDCX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_33549", "species_113601" ], "products": [ "species_113519", "species_113564", "species_42373" ], "modifiers": [ [ "species_10035955", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785" ] }, "reaction_10048504": { "compartment": "compartment_876", "id": "reaction_10048504", "reactome": "R-BTA-425661", "name": "SLC8A1,2,3 exchange 3Na+ for Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_74113" ], "products": [ "species_83910", "species_74112" ], "modifiers": [ [ "species_10048501", "catalyst" ], [ "species_10037000", "inhibitor" ] ], "additional_components": [ "E1B7D0", "ENSBTAT00000014410", "A0A3Q1LST7", "ENSBTAT00000077819", "ENSBTAT00000044622" ] }, "reaction_10072522": { "compartment": "compartment_263163", "id": "reaction_10072522", "reactome": "R-BTA-5626316", "name": "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5626313", "species_83910", "species_167012" ], "products": [ "species_29804", "species_74016", "species_425958" ], "modifiers": [ [ "species_10072519", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006382" ] }, "reaction_10048526": { "compartment": "compartment_876", "id": "reaction_10048526", "reactome": "R-BTA-425678", "name": "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_74016", "species_74113" ], "products": [ "species_74126", "species_83910", "species_74112" ], "modifiers": [ [ "species_10048523", "catalyst" ] ], "additional_components": [ "F1MD60", "ENSBTAT00000008703", "A0A3Q1M073", "ENSBTAT00000074844", "E1BM98", "ENSBTAT00000061324", "E1BGG7", "ENSBTAT00000015768" ] }, "reaction_10048533": { "compartment": "compartment_876", "id": "reaction_10048533", "reactome": "R-BTA-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425815", "species_74016" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10048530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10038895": { "compartment": "compartment_70616", "id": "reaction_10038895", "reactome": "R-BTA-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_113529", "species_29362" ], "products": [ "species_76633", "species_113526", "species_163953" ], "modifiers": [ [ "species_10038882", "catalyst" ], [ "species_10038893", "catalyst" ] ], "additional_components": [ "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219", "Q85BD6", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "P03910", "ENSBTAT00000060552", "F1MK72", "ENSBTAT00000006115", "Q1RMM6", "ENSBTAT00000005722" ] }, "reaction_10080521": { "compartment": "compartment_70616", "id": "reaction_10080521", "reactome": "R-BTA-6799202", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080503", "species_10080485" ], "products": [ "species_10080505" ], "modifiers": [], "additional_components": [ "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10080515": { "compartment": "compartment_70616", "id": "reaction_10080515", "reactome": "R-BTA-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038704", "species_10080511", "species_10080507" ], "products": [ "species_10080513" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077219", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219" ] }, "reaction_10080517": { "compartment": "compartment_70616", "id": "reaction_10080517", "reactome": "R-BTA-6799197", "name": "ND4, ND5 bind the 550kDa complex to form the 815kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038708", "species_10038712", "species_10080505" ], "products": [ "species_10080507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060552", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552" ] }, "reaction_10080519": { "compartment": "compartment_70616", "id": "reaction_10080519", "reactome": "R-BTA-6799199", "name": "COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038740", "species_10080501", "species_10038720", "species_10038716", "species_10038730" ], "products": [ "species_10080503" ], "modifiers": [], "additional_components": [ "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "ENSBTAT00000007761", "ENSBTAT00000060562", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10038647": { "compartment": "compartment_70616", "id": "reaction_10038647", "reactome": "R-BTA-163214", "name": "Electron transfer from reduced cytochrome c to molecular oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10038546", "species_113529" ], "products": [ "species_10038548", "species_163953", "species_113521" ], "modifiers": [ [ "species_10038606", "catalyst" ], [ "species_10038643", "catalyst" ], [ "species_10038611", "catalyst" ], [ "species_10038625", "catalyst" ], [ "species_10038645", "inhibitor" ] ], "additional_components": [ "CHEBI:38573", "P62894", "ENSBTAT00000007918", "P62894", "ENSBTAT00000007918", "CHEBI:38574", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "A6H784", "ENSBTAT00000016742", "A0A3Q1MQS6", "ENSBTAT00000067855", "E1BJK7", "ENSBTAT00000013031", "E1BPX9", "ENSBTAT00000021773", "ENSBTAT00000020289", "A0A3Q1MMW4", "ENSBTAT00000082257", "F1N5P2", "ENSBTAT00000007094", "Q1RMH3", "ENSBTAT00000001069", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10084313": { "compartment": "compartment_70101", "id": "reaction_10084313", "reactome": "R-BTA-8854981", "name": "SHC1 in the RET complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084133" ], "products": [ "species_10074027" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084185": { "compartment": "compartment_70101", "id": "reaction_10084185", "reactome": "R-BTA-8853774", "name": "GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084177" ], "products": [ "species_10084183", "species_29370" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084153": { "compartment": "compartment_70101", "id": "reaction_10084153", "reactome": "R-BTA-8853755", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043197", "species_10074025" ], "products": [ "species_10084151" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10085755": { "compartment": "compartment_876", "id": "reaction_10085755", "reactome": "R-BTA-8871226", "name": "RET binds GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074005", "species_10084137" ], "products": [ "species_10084157" ], "modifiers": [], "additional_components": [ "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398" ] }, "reaction_10084187": { "compartment": "compartment_984", "id": "reaction_10084187", "reactome": "R-BTA-8853789", "name": "GDNF,NRTN bind RET:GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073999", "species_10084157" ], "products": [ "species_10084159" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528" ] }, "reaction_10084379": { "compartment": "compartment_70101", "id": "reaction_10084379", "reactome": "R-BTA-8855747", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084375", "species_10074025" ], "products": [ "species_10084377" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316" ] }, "reaction_10085757": { "compartment": "compartment_876", "id": "reaction_10085757", "reactome": "R-BTA-8871227", "name": "RET binds GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074017", "species_10084137" ], "products": [ "species_10084161" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066172", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084190": { "compartment": "compartment_876", "id": "reaction_10084190", "reactome": "R-BTA-8853792", "name": "RET tyrosine phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084167", "species_113592" ], "products": [ "species_29370", "species_10074025" ], "modifiers": [ [ "species_10084167", "catalyst" ] ], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084309": { "compartment": "compartment_70101", "id": "reaction_10084309", "reactome": "R-BTA-8854897", "name": "p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10084175" ], "products": [ "species_10084177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084149": { "compartment": "compartment_70101", "id": "reaction_10084149", "reactome": "R-BTA-8853753", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10074025" ], "products": [ "species_10084147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10084311": { "compartment": "compartment_70101", "id": "reaction_10084311", "reactome": "R-BTA-8854899", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074025" ], "products": [ "species_10074031" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084169": { "compartment": "compartment_876", "id": "reaction_10084169", "reactome": "R-BTA-8853762", "name": "RET dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084165" ], "products": [ "species_10084167" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084393": { "compartment": "compartment_70101", "id": "reaction_10084393", "reactome": "R-BTA-8855915", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084389", "species_10074025" ], "products": [ "species_10084391" ], "modifiers": [], "additional_components": [ "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10084330": { "compartment": "compartment_984", "id": "reaction_10084330", "reactome": "R-BTA-8855564", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10074025" ], "products": [ "species_10084328" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10084141": { "compartment": "compartment_876", "id": "reaction_10084141", "reactome": "R-BTA-8853745", "name": "RET binds GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073976", "species_10084137" ], "products": [ "species_10084139" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083411", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411" ] }, "reaction_10084352": { "compartment": "compartment_70101", "id": "reaction_10084352", "reactome": "R-BTA-8855617", "name": "2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084348", "species_10074025" ], "products": [ "species_10084350" ], "modifiers": [], "additional_components": [ "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819" ] }, "reaction_10084131": { "compartment": "compartment_70101", "id": "reaction_10084131", "reactome": "R-BTA-8853734", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074027" ], "products": [ "species_10074029" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084194": { "compartment": "compartment_70101", "id": "reaction_10084194", "reactome": "R-BTA-8853793", "name": "p-5Y-RET complexes bind GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084192", "species_10035485" ], "products": [ "species_10084175" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084196": { "compartment": "compartment_984", "id": "reaction_10084196", "reactome": "R-BTA-8853800", "name": "ARTN binds RET:GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073972", "species_10084139" ], "products": [ "species_10084155" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023553", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553" ] }, "reaction_10084135": { "compartment": "compartment_70101", "id": "reaction_10084135", "reactome": "R-BTA-8853737", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035544", "species_10074025" ], "products": [ "species_10084133" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084198": { "compartment": "compartment_984", "id": "reaction_10084198", "reactome": "R-BTA-8853801", "name": "PSPN binds RET:GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084161", "species_10074013" ], "products": [ "species_10084163" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172", "ENSBTAT00000027984", "E1BCL0", "ENSBTAT00000027984", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084326": { "compartment": "compartment_876", "id": "reaction_10084326", "reactome": "R-BTA-8855508", "name": "p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10084183" ], "products": [ "species_10084324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10061049": { "compartment": "compartment_7660", "id": "reaction_10061049", "reactome": "R-BTA-1855206", "name": "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023891" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061017": { "compartment": "compartment_7660", "id": "reaction_10061017", "reactome": "R-BTA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061128": { "compartment": "compartment_7660", "id": "reaction_10061128", "reactome": "R-BTA-1855228", "name": "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023892" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061131": { "compartment": "compartment_7660", "id": "reaction_10061131", "reactome": "R-BTA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061052": { "compartment": "compartment_7660", "id": "reaction_10061052", "reactome": "R-BTA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061119": { "compartment": "compartment_7660", "id": "reaction_10061119", "reactome": "R-BTA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061137": { "compartment": "compartment_7660", "id": "reaction_10061137", "reactome": "R-BTA-1855233", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023907" ], "products": [ "species_113582", "species_2023891" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060993": { "compartment": "compartment_7660", "id": "reaction_10060993", "reactome": "R-BTA-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10060990", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10061031": { "compartment": "compartment_7660", "id": "reaction_10061031", "reactome": "R-BTA-1855185", "name": "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023935" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060951": { "compartment": "compartment_7660", "id": "reaction_10060951", "reactome": "R-BTA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10067955": { "compartment": "compartment_70101", "id": "reaction_10067955", "reactome": "R-BTA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067950" ], "products": [ "species_29372", "species_10067952" ], "modifiers": [ [ "species_10067950", "catalyst" ], [ "species_10067948", "catalyst" ] ], "additional_components": [ "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_29370", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890" ] }, "reaction_10068022": { "compartment": "compartment_70101", "id": "reaction_10068022", "reactome": "R-BTA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068020", "species_10068018" ], "products": [ "species_10067950" ], "modifiers": [], "additional_components": [ "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500" ] }, "reaction_10065708": { "compartment": "compartment_70101", "id": "reaction_10065708", "reactome": "R-BTA-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697" ], "products": [ "species_10065705" ], "modifiers": [ [ "species_10065697", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011761", "F1MW01", "ENSBTAT00000011761", "ENSBTAT00000011761" ] }, "reaction_10065726": { "compartment": "compartment_70101", "id": "reaction_10065726", "reactome": "R-BTA-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697", "species_10065722" ], "products": [ "species_10065724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011761", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "F1MW01", "ENSBTAT00000011761" ] }, "reaction_10091145": { "compartment": "compartment_70101", "id": "reaction_10091145", "reactome": "R-BTA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10091134" ], "products": [ "species_10091143" ], "modifiers": [], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438" ] }, "reaction_10091141": { "compartment": "compartment_1598585", "id": "reaction_10091141", "reactome": "R-BTA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043519" ], "products": [ "species_29420", "species_10091134" ], "modifiers": [ [ "species_10091138", "catalyst" ] ], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29420", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "ENSBTAT00000066656" ] }, "reaction_10091132": { "compartment": "compartment_13231", "id": "reaction_10091132", "reactome": "R-BTA-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10091128" ], "products": [ "species_10091130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "ENSBTAT00000011125", "A6QQV8", "ENSBTAT00000011125", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10091656": { "compartment": "compartment_70101", "id": "reaction_10091656", "reactome": "R-BTA-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091652", "species_10091648" ], "products": [ "species_10091654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065503", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "G3X8E2", "ENSBTAT00000065503" ] }, "reaction_10091658": { "compartment": "compartment_13231", "id": "reaction_10091658", "reactome": "R-BTA-9668395", "name": "CHMP7 binds CC2D1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091644", "species_10091640" ], "products": [ "species_10091646" ], "modifiers": [], "additional_components": [ "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000021129", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091661": { "compartment": "compartment_70101", "id": "reaction_10091661", "reactome": "R-BTA-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29356", "species_113592" ], "products": [ "species_29372", "species_10040834", "species_29370" ], "modifiers": [ [ "species_10091648", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091634": { "compartment": "compartment_70101", "id": "reaction_10091634", "reactome": "R-BTA-9668335", "name": "CHMP7 binds LEMD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052771", "species_10070769" ], "products": [ "species_10091632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017987", "ENSBTAT00000020642", "E1B828", "ENSBTAT00000020642", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091663": { "compartment": "compartment_7660", "id": "reaction_10091663", "reactome": "R-BTA-9668904", "name": "Formation of the CTF18 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039904", "species_10039900", "species_10039896" ], "products": [ "species_10039906" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020389", "ENSBTAT00000002226", "ENSBTAT00000026311", "E1B8Q4", "ENSBTAT00000026311", "P0CG11", "ENSBTAT00000002226", "F1MTU0", "ENSBTAT00000020389" ] }, "reaction_10057418": { "compartment": "compartment_876", "id": "reaction_10057418", "reactome": "R-BTA-1296046", "name": "KCNJs transport K+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10057415", "catalyst" ] ], "additional_components": [ "O19182", "ENSBTAT00000010914", "A0A3Q1M4V6", "ENSBTAT00000078632", "E1BCI4", "ENSBTAT00000000089" ] }, "reaction_10064591": { "compartment": "compartment_70616", "id": "reaction_10064591", "reactome": "R-BTA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10064588", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007549" ] }, "reaction_10046968": { "compartment": "compartment_70101", "id": "reaction_10046968", "reactome": "R-BTA-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389545", "species_29366" ], "products": [ "species_29406", "species_70106", "species_113528", "species_29364" ], "modifiers": [ [ "species_10046965", "catalyst" ] ], "additional_components": [ "A0A140T8A5", "ENSBTAT00000027348" ] }, "reaction_10058524": { "compartment": "compartment_70101", "id": "reaction_10058524", "reactome": "R-BTA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10058521", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411" ] }, "reaction_10058511": { "compartment": "compartment_70101", "id": "reaction_10058511", "reactome": "R-BTA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10058500", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ], [ "species_10058509", "inhibitor" ] ], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10058785": { "compartment": "compartment_70101", "id": "reaction_10058785", "reactome": "R-BTA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10058778" ], "products": [ "species_29370", "species_10058521" ], "modifiers": [ [ "species_10058782", "catalyst" ] ], "additional_components": [ "A0A3Q1MA59", "ENSBTAT00000030411", "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411", "ENSBTAT00000003877" ] }, "reaction_10058514": { "compartment": "compartment_70101", "id": "reaction_10058514", "reactome": "R-BTA-1474158", "name": "GCHFR binds to GCH1 and negatively regulates its activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058500", "species_10058507" ], "products": [ "species_10058509" ], "modifiers": [], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10085853": { "compartment": "compartment_70101", "id": "reaction_10085853", "reactome": "R-BTA-8874705", "name": "TTPA transports alpha-TOH from lysosomal membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085849" ], "products": [ "species_10085851" ], "modifiers": [], "additional_components": [ "species_8874708", "F1N086", "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10085855": { "compartment": "compartment_70101", "id": "reaction_10085855", "reactome": "R-BTA-8874718", "name": "TTPA binds alpha-TOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085847", "species_8874708" ], "products": [ "species_10085849" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10081928": { "compartment": "compartment_17957", "id": "reaction_10081928", "reactome": "R-BTA-6806647", "name": "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10081925", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064807" ] }, "reaction_10038427": { "compartment": "compartment_12045", "id": "reaction_10038427", "reactome": "R-BTA-159790", "name": "VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10038422", "catalyst" ], [ "species_10038425", "inhibitor" ] ], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10090493": { "compartment": "compartment_12045", "id": "reaction_10090493", "reactome": "R-BTA-9026967", "name": "VKORC1 inhibitors binds VKORC1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038422", "species_9035082" ], "products": [ "species_10038425" ], "modifiers": [], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10081935": { "compartment": "compartment_17957", "id": "reaction_10081935", "reactome": "R-BTA-6806674", "name": "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806891", "species_6806657" ], "products": [ "species_6806362", "species_6806656" ], "modifiers": [ [ "species_10081932", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018617" ] }, "reaction_10054393": { "compartment": "compartment_70101", "id": "reaction_10054393", "reactome": "R-BTA-975629", "name": "RDH11 reduces RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10035574", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "ENSBTAT00000002535" ] }, "reaction_10066249": { "compartment": "compartment_70101", "id": "reaction_10066249", "reactome": "R-BTA-2855259", "name": "atROL binds RBP1 (parenchymal cell)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473610", "species_10035554" ], "products": [ "species_10065443" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590" ] }, "reaction_10054395": { "compartment": "compartment_70101", "id": "reaction_10054395", "reactome": "R-BTA-975633", "name": "atROL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975590" ], "products": [ "species_10054388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10070971": { "compartment": "compartment_984", "id": "reaction_10070971", "reactome": "R-BTA-5246478", "name": "APOM binds retinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070967", "species_5246487" ], "products": [ "species_10070969" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075540", "species_975590", "species_5362520", "species_215573", "species_975590", "species_5362520", "species_215573", "A0A3Q1MB70", "ENSBTAT00000075540" ] }, "reaction_10065437": { "compartment": "compartment_70101", "id": "reaction_10065437", "reactome": "R-BTA-2399913", "name": "atRAL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975622" ], "products": [ "species_10054390" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975622", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10069948": { "compartment": "compartment_5460", "id": "reaction_10069948", "reactome": "R-BTA-5164399", "name": "BCO2:Fe2+ cleaves betaC to APO10al and bION", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_5164389" ], "products": [ "species_5164390", "species_5164383" ], "modifiers": [ [ "species_10069945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N2Z9", "ENSBTAT00000048395" ] }, "reaction_10054382": { "compartment": "compartment_984", "id": "reaction_10054382", "reactome": "R-BTA-975594", "name": "PLB1 hydrolyses RPALM to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10065441": { "compartment": "compartment_70101", "id": "reaction_10065441", "reactome": "R-BTA-2404142", "name": "atROL binds RBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473616" ], "products": [ "species_10065439" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065445": { "compartment": "compartment_70101", "id": "reaction_10065445", "reactome": "R-BTA-2404144", "name": "Parenchymal atROL translocates to HSCs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065443" ], "products": [ "species_10035554", "species_2473616" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10054404": { "compartment": "compartment_70101", "id": "reaction_10054404", "reactome": "R-BTA-975635", "name": "BCMO1:Fe2+ cleaves betaC to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_975643" ], "products": [ "species_975622" ], "modifiers": [ [ "species_10054401", "catalyst" ] ], "additional_components": [ "F1N3B7", "ENSBTAT00000048748", "species_71067" ] }, "reaction_10054375": { "compartment": "compartment_984", "id": "reaction_10054375", "reactome": "R-BTA-975593", "name": "PNLIP:CLPS hydrolyses RPALM to atROL and PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10066247": { "compartment": "compartment_70101", "id": "reaction_10066247", "reactome": "R-BTA-2855252", "name": "AKRs reduce RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10066244", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086", "F1N678", "ENSBTAT00000002073" ] }, "reaction_10042657": { "compartment": "compartment_876", "id": "reaction_10042657", "reactome": "R-BTA-199219", "name": "SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199238", "species_74113" ], "products": [ "species_83910", "species_199207" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10066401": { "compartment": "compartment_70101", "id": "reaction_10066401", "reactome": "R-BTA-2993447", "name": "HLCS biotinylates 6x(PCCA:PCCB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066388", "species_113592", "species_199207" ], "products": [ "species_111294", "species_10066394", "species_76577" ], "modifiers": [ [ "species_10066398", "catalyst" ] ], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "ENSBTAT00000057284" ] }, "reaction_10067733": { "compartment": "compartment_70101", "id": "reaction_10067733", "reactome": "R-BTA-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066394" ], "products": [ "species_10033909" ], "modifiers": [], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10042936": { "compartment": "compartment_70616", "id": "reaction_10042936", "reactome": "R-BTA-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10042933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048106" ] }, "reaction_10081339": { "compartment": "compartment_5460", "id": "reaction_10081339", "reactome": "R-BTA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10042940": { "compartment": "compartment_876", "id": "reaction_10042940", "reactome": "R-BTA-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10082078": { "compartment": "compartment_70101", "id": "reaction_10082078", "reactome": "R-BTA-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111353", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_197969" ], "modifiers": [ [ "species_10082075", "catalyst" ] ], "additional_components": [ "E1BMG9", "ENSBTAT00000043693" ] }, "reaction_10042929": { "compartment": "compartment_876", "id": "reaction_10042929", "reactome": "R-BTA-200652", "name": "SLC19A1 transports 5-methyl-THF from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200709" ], "products": [ "species_200665" ], "modifiers": [ [ "species_10042926", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082124" ] }, "reaction_10041840": { "compartment": "compartment_70101", "id": "reaction_10041840", "reactome": "R-BTA-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73604", "species_29364" ], "products": [ "species_111355", "species_29366" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10087442": { "compartment": "compartment_984", "id": "reaction_10087442", "reactome": "R-BTA-8942344", "name": "FOLR2 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086761" ], "products": [ "species_197965", "species_10086759" ], "modifiers": [], "additional_components": [ "Q0VCN9", "ENSBTAT00000027602", "species_197965", "ENSBTAT00000027602" ] }, "reaction_10092306": { "compartment": "compartment_70101", "id": "reaction_10092306", "reactome": "R-BTA-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10092303", "catalyst" ] ], "additional_components": [ "A0A140T872", "ENSBTAT00000010103" ] }, "reaction_10082068": { "compartment": "compartment_5460", "id": "reaction_10082068", "reactome": "R-BTA-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_6808499", "species_113521" ], "products": [ "species_113529", "species_200679", "species_113600", "species_29376" ], "modifiers": [ [ "species_10082065", "catalyst" ] ], "additional_components": [ "E1BDG9", "ENSBTAT00000008298" ] }, "reaction_10086763": { "compartment": "compartment_984", "id": "reaction_10086763", "reactome": "R-BTA-8940134", "name": "FOLR2 binds FOLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716", "species_10086759" ], "products": [ "species_10086761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027602", "Q0VCN9", "ENSBTAT00000027602", "species_197965" ] }, "reaction_10042922": { "compartment": "compartment_876", "id": "reaction_10042922", "reactome": "R-BTA-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10041838": { "compartment": "compartment_70101", "id": "reaction_10041838", "reactome": "R-BTA-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10081346": { "compartment": "compartment_70101", "id": "reaction_10081346", "reactome": "R-BTA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10081343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026669" ] }, "reaction_10076485": { "compartment": "compartment_70616", "id": "reaction_10076485", "reactome": "R-BTA-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_5693984", "species_113521" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10076482", "catalyst" ] ], "additional_components": [ "Q3SZ20", "ENSBTAT00000038244" ] }, "reaction_10081349": { "compartment": "compartment_5460", "id": "reaction_10081349", "reactome": "R-BTA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10041817": { "compartment": "compartment_70101", "id": "reaction_10041817", "reactome": "R-BTA-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10041814", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1NKT9", "ENSBTAT00000069099" ] }, "reaction_10042906": { "compartment": "compartment_5460", "id": "reaction_10042906", "reactome": "R-BTA-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938078", "species_8938090" ], "modifiers": [ [ "species_10042903", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NCV5", "ENSBTAT00000074137" ] }, "reaction_10088666": { "compartment": "compartment_5460", "id": "reaction_10088666", "reactome": "R-BTA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10088663", "catalyst" ] ], "additional_components": [ "A0A3Q1LR42", "ENSBTAT00000077253" ] }, "reaction_10086748": { "compartment": "compartment_984", "id": "reaction_10086748", "reactome": "R-BTA-8940070", "name": "NT5E:Zn2+ hydrolyses NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_109277", "species_8940067" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10086750": { "compartment": "compartment_984", "id": "reaction_10086750", "reactome": "R-BTA-8940074", "name": "NT5E:Zn2+ hydrolyses NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8940067" ], "products": [ "species_109277", "species_8940077" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10085374": { "compartment": "compartment_984", "id": "reaction_10085374", "reactome": "R-BTA-8870346", "name": "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10085371", "catalyst" ] ], "additional_components": [ "F1MLP3", "ENSBTAT00000008097" ] }, "reaction_10085362": { "compartment": "compartment_70101", "id": "reaction_10085362", "reactome": "R-BTA-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10085365": { "compartment": "compartment_70101", "id": "reaction_10085365", "reactome": "R-BTA-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10081977": { "compartment": "compartment_5460", "id": "reaction_10081977", "reactome": "R-BTA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10081974", "catalyst" ] ], "additional_components": [ "A0A3Q1MF13", "ENSBTAT00000080451" ] }, "reaction_10071643": { "compartment": "compartment_70101", "id": "reaction_10071643", "reactome": "R-BTA-5359451", "name": "NNMT transfers CH3 from SAM to NAM to form MNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197277", "species_71284" ], "products": [ "species_549282", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10086623": { "compartment": "compartment_70101", "id": "reaction_10086623", "reactome": "R-BTA-8938073", "name": "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938276", "species_29360" ], "products": [ "species_197277", "species_8938282" ], "modifiers": [ [ "species_10086620", "catalyst" ] ], "additional_components": [ "F6R6Y8", "ENSBTAT00000029045", "A0A3Q1M0E5", "ENSBTAT00000084343", "F1MRP9", "ENSBTAT00000012765" ] }, "reaction_10082143": { "compartment": "compartment_17951", "id": "reaction_10082143", "reactome": "R-BTA-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192305", "species_389620" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10082140", "catalyst" ] ], "additional_components": [ "ENSBTAT00000039965" ] }, "reaction_10041824": { "compartment": "compartment_70101", "id": "reaction_10041824", "reactome": "R-BTA-197250", "name": "NAMPT transfers PRIB to NAM to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197277" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041821", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083136" ] }, "reaction_10041808": { "compartment": "compartment_70101", "id": "reaction_10041808", "reactome": "R-BTA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041805", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "A0A3Q1N5S3", "ENSBTAT00000084634" ] }, "reaction_10081984": { "compartment": "compartment_5460", "id": "reaction_10081984", "reactome": "R-BTA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10081981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015238" ] }, "reaction_10088867": { "compartment": "compartment_984", "id": "reaction_10088867", "reactome": "R-BTA-8956458", "name": "RNLS:FAD oxidises dh-beta-NAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_352327", "species_8956473" ], "products": [ "species_352330", "species_351629" ], "modifiers": [ [ "species_10088864", "catalyst" ] ], "additional_components": [ "CHEBI:90174", "CHEBI:90171", "A0A3Q1NF84", "ENSBTAT00000069540", "species_113596" ] }, "reaction_10049170": { "compartment": "compartment_876", "id": "reaction_10049170", "reactome": "R-BTA-429749", "name": "SLC5A8 transports monocarboxylates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429739", "species_74113" ], "products": [ "species_83910", "species_429748" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_76179", "species_2022890", "CHEBI:30768", "species_76179", "species_113557", "species_2022890", "species_373863", "CHEBI:30768", "species_197230", "ENSBTAT00000015315" ] }, "reaction_10085352": { "compartment": "compartment_70101", "id": "reaction_10085352", "reactome": "R-BTA-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10085359": { "compartment": "compartment_70101", "id": "reaction_10085359", "reactome": "R-BTA-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10042915": { "compartment": "compartment_7660", "id": "reaction_10042915", "reactome": "R-BTA-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200492", "species_29358" ], "products": [ "species_8878981", "species_200499" ], "modifiers": [ [ "species_10042912", "catalyst" ] ], "additional_components": [ "Q0VD50", "ENSBTAT00000082151", "species_29426" ] }, "reaction_10041831": { "compartment": "compartment_70101", "id": "reaction_10041831", "reactome": "R-BTA-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_70106", "species_197238" ], "products": [ "species_111294", "species_113528", "species_197220" ], "modifiers": [ [ "species_10041828", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083204" ] }, "reaction_10086630": { "compartment": "compartment_984", "id": "reaction_10086630", "reactome": "R-BTA-8938076", "name": "CD38 hydrolyses NAD+ to NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10086627", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073897" ] }, "reaction_10053298": { "compartment": "compartment_70101", "id": "reaction_10053298", "reactome": "R-BTA-947531", "name": "Molybdenum ion transfer onto molybdopterin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947561", "species_947496" ], "products": [ "species_111294", "species_947539", "species_76577" ], "modifiers": [ [ "species_10053295", "catalyst" ] ], "additional_components": [ "A0A3Q1ME13", "ENSBTAT00000081310", "species_29926" ] }, "reaction_10053266": { "compartment": "compartment_70101", "id": "reaction_10053266", "reactome": "R-BTA-947499", "name": "Exchange of oxygen with sulfur in MoCo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947539", "species_111707" ], "products": [ "species_947575", "species_29432" ], "modifiers": [ [ "species_10053263", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065375" ] }, "reaction_10053287": { "compartment": "compartment_70101", "id": "reaction_10053287", "reactome": "R-BTA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10053272" ], "products": [ "species_29432", "species_10053277" ], "modifiers": [ [ "species_10053284", "catalyst" ] ], "additional_components": [ "species_29426", "A1A4L8", "ENSBTAT00000070167", "A1A4L8", "ENSBTAT00000070167", "species_29426", "A5PKG4", "ENSBTAT00000009149" ] }, "reaction_10053352": { "compartment": "compartment_70101", "id": "reaction_10053352", "reactome": "R-BTA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10066619": { "compartment": "compartment_70101", "id": "reaction_10066619", "reactome": "R-BTA-3204311", "name": "AOX1 oxidises PXL to PDXate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965131" ], "products": [ "species_3204324", "species_29408" ], "modifiers": [ [ "species_10066616", "catalyst" ] ], "additional_components": [ "CHEBI:33722", "CHEBI:44074", "species_113596", "A0A3Q1LJG6", "ENSBTAT00000075745" ] }, "reaction_10053361": { "compartment": "compartment_70101", "id": "reaction_10053361", "reactome": "R-BTA-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_964952" ], "products": [ "species_29390", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053363": { "compartment": "compartment_70101", "id": "reaction_10053363", "reactome": "R-BTA-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965146" ], "products": [ "species_29390", "species_31633", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053348": { "compartment": "compartment_70101", "id": "reaction_10053348", "reactome": "R-BTA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10053350": { "compartment": "compartment_70101", "id": "reaction_10053350", "reactome": "R-BTA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10041753": { "compartment": "compartment_70101", "id": "reaction_10041753", "reactome": "R-BTA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10041750", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LMH4", "ENSBTAT00000085465" ] }, "reaction_10042799": { "compartment": "compartment_876", "id": "reaction_10042799", "reactome": "R-BTA-199626", "name": "SLC19A2/3 transport extracellular THMN to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199622" ], "products": [ "species_196934" ], "modifiers": [ [ "species_10042796", "catalyst" ] ], "additional_components": [ "A7E352", "ENSBTAT00000084175", "E1BLU2", "ENSBTAT00000027006" ] }, "reaction_10066585": { "compartment": "compartment_5460", "id": "reaction_10066585", "reactome": "R-BTA-3159253", "name": "MMAB transfers adenosyl group from ATP to cob(I)alamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3159260", "species_113593" ], "products": [ "species_3159274", "species_3159297" ], "modifiers": [ [ "species_10066582", "catalyst" ] ], "additional_components": [ "A0A3Q1NBS4", "ENSBTAT00000056628" ] }, "reaction_10066587": { "compartment": "compartment_5460", "id": "reaction_10066587", "reactome": "R-BTA-3159259", "name": "MMAA:MUT binds AdoCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033882", "species_3159297" ], "products": [ "species_10033884" ], "modifiers": [], "additional_components": [ "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806", "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10066458": { "compartment": "compartment_984", "id": "reaction_10066458", "reactome": "R-BTA-3000120", "name": "GIF binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066454", "species_3000125" ], "products": [ "species_10066456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066461": { "compartment": "compartment_984", "id": "reaction_10066461", "reactome": "R-BTA-3000122", "name": "CD320 transports extracellular TCII:Cbl to endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066428", "species_10066440" ], "products": [ "species_10066438" ], "modifiers": [ [ "species_10066440", "catalyst" ] ], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777", "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10076254": { "compartment": "compartment_984", "id": "reaction_10076254", "reactome": "R-BTA-5693319", "name": "CTRC hydrolyses PRSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10076243" ], "products": [ "species_10076247", "species_10076245" ], "modifiers": [ [ "species_10076251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000071882" ] }, "reaction_10066526": { "compartment": "compartment_984", "id": "reaction_10066526", "reactome": "R-BTA-3132753", "name": "Pancreatic proteases degrade TCN1:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066519" ], "products": [ "species_3000125" ], "modifiers": [ [ "species_10066523", "catalyst" ] ], "additional_components": [ "species_3000241", "E1BCU6", "ENSBTAT00000027423", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10066430": { "compartment": "compartment_984", "id": "reaction_10066430", "reactome": "R-BTA-3000074", "name": "TCII binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066426", "species_3000125" ], "products": [ "species_10066428" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066576": { "compartment": "compartment_70101", "id": "reaction_10066576", "reactome": "R-BTA-3149563", "name": "MMADHC targets transport of cytosolic cob(II)alamin to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149564" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066450": { "compartment": "compartment_17940", "id": "reaction_10066450", "reactome": "R-BTA-3000112", "name": "Endosomal TCII:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066442" ], "products": [ "species_10066448" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066569": { "compartment": "compartment_70101", "id": "reaction_10066569", "reactome": "R-BTA-3149492", "name": "cob(II)alamin dissociates from MMACHC:MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066473": { "compartment": "compartment_161320", "id": "reaction_10066473", "reactome": "R-BTA-3000263", "name": "TCII:Cbl is degraded to release Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066448" ], "products": [ "species_3000239" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066571": { "compartment": "compartment_70101", "id": "reaction_10066571", "reactome": "R-BTA-3149494", "name": "MMACHC:cob(II)alamin binds MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066563", "species_10066499" ], "products": [ "species_10066565" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638" ] }, "reaction_10066444": { "compartment": "compartment_74700", "id": "reaction_10066444", "reactome": "R-BTA-3000109", "name": "CD320:TCII:Cbl dissociates into CD320 and TCII:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066438" ], "products": [ "species_10066442", "species_10066440" ], "modifiers": [], "additional_components": [ "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10066574": { "compartment": "compartment_70101", "id": "reaction_10066574", "reactome": "R-BTA-3149519", "name": "MMACHC decyanates CNCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10066497", "species_29364", "species_3149505" ], "products": [ "species_10066499", "species_29366", "species_1130611" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10066528": { "compartment": "compartment_984", "id": "reaction_10066528", "reactome": "R-BTA-3132759", "name": "TCN1 binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3132775" ], "products": [ "species_10066519", "species_3132772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066882": { "compartment": "compartment_984", "id": "reaction_10066882", "reactome": "R-BTA-3245898", "name": "TCN1 binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3000125" ], "products": [ "species_10066519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066471": { "compartment": "compartment_17940", "id": "reaction_10066471", "reactome": "R-BTA-3000247", "name": "Endosomal GIF:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066469" ], "products": [ "species_10066465" ], "modifiers": [], "additional_components": [ "species_3000241", "E1BCN2", "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066502": { "compartment": "compartment_70101", "id": "reaction_10066502", "reactome": "R-BTA-3095889", "name": "MMACHC reduces Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000241", "species_70106", "species_10066497", "species_29364" ], "products": [ "species_10066499", "species_29366" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10042648": { "compartment": "compartment_876", "id": "reaction_10042648", "reactome": "R-BTA-199206", "name": "SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199192", "species_74113" ], "products": [ "species_83910", "species_196820" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10041737": { "compartment": "compartment_70101", "id": "reaction_10041737", "reactome": "R-BTA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10041734", "catalyst" ] ], "additional_components": [ "A0A3S5ZP75", "ENSBTAT00000017259" ] }, "reaction_10041756": { "compartment": "compartment_70101", "id": "reaction_10041756", "reactome": "R-BTA-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_29370", "species_76194" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10042655": { "compartment": "compartment_70616", "id": "reaction_10042655", "reactome": "R-BTA-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10042652", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031344" ] }, "reaction_10041744": { "compartment": "compartment_70101", "id": "reaction_10041744", "reactome": "R-BTA-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_111294", "species_196778" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10041765": { "compartment": "compartment_70101", "id": "reaction_10041765", "reactome": "R-BTA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10041762", "catalyst" ] ], "additional_components": [ "species_73524", "A0A3Q1MNK4", "ENSBTAT00000076608" ] }, "reaction_10053048": { "compartment": "compartment_70101", "id": "reaction_10053048", "reactome": "R-BTA-933533", "name": "Dimerization of p-IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039550" ], "products": [ "species_10039554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053046": { "compartment": "compartment_13231", "id": "reaction_10053046", "reactome": "R-BTA-933531", "name": "Translocation of p-IRF7:p-IRF7 to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10037203": { "compartment": "compartment_7660", "id": "reaction_10037203", "reactome": "R-BTA-113402", "name": "Formation of DSIF:NELF:early elongation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037126", "species_10037171", "species_30595" ], "products": [ "species_10037173", "species_30595" ], "modifiers": [], "additional_components": [ "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "species_110614", "species_113592", "species_29494", "species_29438", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "species_110614", "species_113592", "species_29494", "species_29438" ] }, "reaction_10037205": { "compartment": "compartment_7660", "id": "reaction_10037205", "reactome": "R-BTA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037169", "species_10037137" ], "products": [ "species_10037171" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412" ] }, "reaction_10086136": { "compartment": "compartment_13946", "id": "reaction_10086136", "reactome": "R-BTA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086105" ], "products": [ "species_29420", "species_10086115", "species_10085883" ], "modifiers": [ [ "species_10086133", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N5L8", "ENSBTAT00000086931", "A0A3Q1MK52", "ENSBTAT00000082010", "F1MXL8", "ENSBTAT00000009769" ] }, "reaction_10085932": { "compartment": "compartment_437051", "id": "reaction_10085932", "reactome": "R-BTA-8876188", "name": "DENND4s exchange GTP for GDP on RAB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085911", "species_29438" ], "products": [ "species_29420", "species_10085915", "species_10085883" ], "modifiers": [ [ "species_10085929", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QLS9", "ENSBTAT00000001303", "species_29420", "A6QLS9", "ENSBTAT00000001303", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BJE1", "ENSBTAT00000022733", "F1N377", "ENSBTAT00000034026", "A0A3Q1NBE4", "ENSBTAT00000073212" ] }, "reaction_10086097": { "compartment": "compartment_171062", "id": "reaction_10086097", "reactome": "R-BTA-8877311", "name": "RAB31 GEFs exchange GTP for GDP on RAB31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086086", "species_29438" ], "products": [ "species_29420", "species_10086090", "species_10085883" ], "modifiers": [ [ "species_10086094", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29420", "Q08DC2", "ENSBTAT00000075871", "Q08DC2", "ENSBTAT00000075871", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000013748" ] }, "reaction_10086209": { "compartment": "compartment_20699", "id": "reaction_10086209", "reactome": "R-BTA-8877813", "name": "DENND5A,B exchange GTP for GDP on RAB39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086188" ], "products": [ "species_10086196", "species_29420", "species_10085883" ], "modifiers": [ [ "species_10086206", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "G3X7D3", "ENSBTAT00000024288", "species_29420", "G3X7D3", "ENSBTAT00000024288", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MUN3", "ENSBTAT00000069720", "F1MQ87", "ENSBTAT00000027075" ] }, "reaction_10086019": { "compartment": "compartment_70101", "id": "reaction_10086019", "reactome": "R-BTA-8876616", "name": "DENND6A,B exchange GTP for GDP on RAB14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086008" ], "products": [ "species_29420", "species_10086012", "species_10085883" ], "modifiers": [ [ "species_10086016", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3ZBG1", "ENSBTAT00000023671", "species_29420", "Q3ZBG1", "ENSBTAT00000023671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000067401" ] }, "reaction_10085988": { "compartment": "compartment_262783", "id": "reaction_10085988", "reactome": "R-BTA-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10085979" ], "products": [ "species_29420", "species_10085983", "species_10085883" ], "modifiers": [ [ "species_10085985", "catalyst" ] ], "additional_components": [ "species_29420", "A6QPX8", "ENSBTAT00000013671", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QPX8", "ENSBTAT00000013671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MCL3", "ENSBTAT00000087265" ] }, "reaction_10086054": { "compartment": "compartment_171062", "id": "reaction_10086054", "reactome": "R-BTA-8876837", "name": "RAB21 GEFs exchange GTP for GDP on RAB21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086037" ], "products": [ "species_29420", "species_10085883", "species_10086041" ], "modifiers": [ [ "species_10086051", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "F1MPP1", "ENSBTAT00000025807", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29438", "F1MPP1", "ENSBTAT00000025807", "A0A3Q1M4Y7", "ENSBTAT00000075635", "A0A3Q1M373", "ENSBTAT00000078087" ] }, "reaction_10086182": { "compartment": "compartment_5668575", "id": "reaction_10086182", "reactome": "R-BTA-8877760", "name": "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086161" ], "products": [ "species_29420", "species_10085883", "species_10086169" ], "modifiers": [ [ "species_10086179", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29438", "E1B7M9", "ENSBTAT00000056415", "A0A3Q1N720", "ENSBTAT00000071404" ] }, "reaction_10048567": { "compartment": "compartment_876", "id": "reaction_10048567", "reactome": "R-BTA-425994", "name": "Na+/H+ exchanger transport (at cell membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10048564", "catalyst" ] ], "additional_components": [ "E1BB11", "ENSBTAT00000002235", "F1MU00", "ENSBTAT00000006073", "E1B8Y0", "ENSBTAT00000054801" ] }, "reaction_10048550": { "compartment": "compartment_171062", "id": "reaction_10048550", "reactome": "R-BTA-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10048547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073706" ] }, "reaction_10058841": { "compartment": "compartment_12045", "id": "reaction_10058841", "reactome": "R-BTA-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10059000": { "compartment": "compartment_12045", "id": "reaction_10059000", "reactome": "R-BTA-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10059851": { "compartment": "compartment_984", "id": "reaction_10059851", "reactome": "R-BTA-1602377", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_426658" ], "products": [ "species_1602420", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058874": { "compartment": "compartment_12045", "id": "reaction_10058874", "reactome": "R-BTA-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10058975": { "compartment": "compartment_12045", "id": "reaction_10058975", "reactome": "R-BTA-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058972", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059026": { "compartment": "compartment_12045", "id": "reaction_10059026", "reactome": "R-BTA-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10059023", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576" ] }, "reaction_10048682": { "compartment": "compartment_7660", "id": "reaction_10048682", "reactome": "R-BTA-427337", "name": "MBD2 binds methylcytosine in chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035250", "species_10035235" ], "products": [ "species_10035252" ], "modifiers": [], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000053498", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10048717": { "compartment": "compartment_7660", "id": "reaction_10048717", "reactome": "R-BTA-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048700", "species_427523" ], "products": [ "species_427497", "species_10044309", "species_427498" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10048720": { "compartment": "compartment_7660", "id": "reaction_10048720", "reactome": "R-BTA-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044309" ], "products": [ "species_77502", "species_10048712" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10044361": { "compartment": "compartment_7660", "id": "reaction_10044361", "reactome": "R-BTA-212252", "name": "Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044357", "species_10044309" ], "products": [ "species_10044359" ], "modifiers": [], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044381": { "compartment": "compartment_7660", "id": "reaction_10044381", "reactome": "R-BTA-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044359" ], "products": [ "species_77502", "species_10044378" ], "modifiers": [ [ "species_10044359", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044333": { "compartment": "compartment_7660", "id": "reaction_10044333", "reactome": "R-BTA-212222", "name": "PRC2 recruits DNA methyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044307", "species_10044329" ], "products": [ "species_10044331" ], "modifiers": [], "additional_components": [ "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10044390": { "compartment": "compartment_7660", "id": "reaction_10044390", "reactome": "R-BTA-212269", "name": "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044331" ], "products": [ "species_77502", "species_10044387" ], "modifiers": [ [ "species_10044331", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10070700": { "compartment": "compartment_7660", "id": "reaction_10070700", "reactome": "R-BTA-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10036698" ], "products": [ "species_10036706", "species_5221065" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10070702": { "compartment": "compartment_7660", "id": "reaction_10070702", "reactome": "R-BTA-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10036698" ], "products": [ "species_10036706", "species_5221064" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10071065": { "compartment": "compartment_7660", "id": "reaction_10071065", "reactome": "R-BTA-5250938", "name": "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10035231" ], "products": [ "species_2485002", "species_10071014" ], "modifiers": [ [ "species_10071062", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "E1BP59", "ENSBTAT00000061193", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "A5PJQ1", "ENSBTAT00000017097", "E1B6X6", "ENSBTAT00000072070", "E1BKX3", "ENSBTAT00000009771", "F1MX61", "ENSBTAT00000011734", "A0A3Q1M384", "ENSBTAT00000070441", "F6QHI8", "ENSBTAT00000019351", "Q1JQD6", "ENSBTAT00000043676", "Q32LB6", "ENSBTAT00000004611", "F1MUD5", "ENSBTAT00000056158" ] }, "reaction_10065336": { "compartment": "compartment_984", "id": "reaction_10065336", "reactome": "R-BTA-2395328", "name": "LTBP1, LTBP3 bind TGF-Beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065332", "species_10065308" ], "products": [ "species_10065334" ], "modifiers": [], "additional_components": [ "A6QP91", "ENSBTAT00000015925", "ENSBTAT00000075583", "A0A3Q1LJU9", "ENSBTAT00000075583", "A6QP91", "ENSBTAT00000015925" ] }, "reaction_10065435": { "compartment": "compartment_984", "id": "reaction_10065435", "reactome": "R-BTA-2396399", "name": "Fibrillins bind BMPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065431", "species_10063837" ], "products": [ "species_10065433" ], "modifiers": [], "additional_components": [ "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807", "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807" ] }, "reaction_10064435": { "compartment": "compartment_984", "id": "reaction_10064435", "reactome": "R-BTA-2161282", "name": "Elastic fibres bind associated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064421", "species_10064431" ], "products": [ "species_10064433" ], "modifiers": [], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049" ] }, "reaction_10063839": { "compartment": "compartment_984", "id": "reaction_10063839", "reactome": "R-BTA-2129362", "name": "Fibrillin microfibril assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063825" ], "products": [ "species_10063837" ], "modifiers": [], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360" ] }, "reaction_10064437": { "compartment": "compartment_984", "id": "reaction_10064437", "reactome": "R-BTA-2161293", "name": "Tropoelastin forms aggregate globules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059655" ], "products": [ "species_10063809" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399" ] }, "reaction_10067346": { "compartment": "compartment_70101", "id": "reaction_10067346", "reactome": "R-BTA-3295580", "name": "TRPM4,5 transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10067343", "catalyst" ] ], "additional_components": [ "E1BNX9", "ENSBTAT00000008077", "A0A3Q1M0Y5", "ENSBTAT00000075032" ] }, "reaction_10092050": { "compartment": "compartment_70101", "id": "reaction_10092050", "reactome": "R-BTA-9701055", "name": "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10092047", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G5E522", "ENSBTAT00000002668", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10067332": { "compartment": "compartment_70101", "id": "reaction_10067332", "reactome": "R-BTA-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10067306", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G3MY82", "ENSBTAT00000065500", "E1BPC8", "ENSBTAT00000019509", "G3N2S2", "ENSBTAT00000066065", "Q5EA32", "ENSBTAT00000003922", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LTG6", "ENSBTAT00000070979", "F1MPF0", "ENSBTAT00000044081", "P79100", "ENSBTAT00000065392", "E1BAN3", "ENSBTAT00000033438", "F1N232", "ENSBTAT00000068680", "A0A3Q1M4W2", "ENSBTAT00000077611", "E1BDG0", "ENSBTAT00000022589", "E1BCP0", "ENSBTAT00000085000", "G5E522", "ENSBTAT00000002668", "E1B6Y9", "ENSBTAT00000002485", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10039604": { "compartment": "compartment_70616", "id": "reaction_10039604", "reactome": "R-BTA-170026", "name": "Protons are translocated from the intermembrane space to the matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953" ], "products": [ "species_113529" ], "modifiers": [ [ "species_10039233", "catalyst" ], [ "species_30495", "catalyst" ], [ "species_170037", "inhibitor" ] ], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_113592", "species_29370", "species_29420", "species_29438" ] }, "reaction_10039240": { "compartment": "compartment_70616", "id": "reaction_10039240", "reactome": "R-BTA-166214", "name": "FA anion flip-flops to the opposite surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039235" ], "products": [ "species_10039237" ], "modifiers": [ [ "species_10039235", "catalyst" ] ], "additional_components": [ "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039242": { "compartment": "compartment_70616", "id": "reaction_10039242", "reactome": "R-BTA-166220", "name": "FA anion diffuses laterally to UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039233", "species_166213" ], "products": [ "species_10039235" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039254": { "compartment": "compartment_70616", "id": "reaction_10039254", "reactome": "R-BTA-166387", "name": "The FA anion diffuses away laterally from UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039237" ], "products": [ "species_166216", "species_10039233" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10073400": { "compartment": "compartment_7660", "id": "reaction_10073400", "reactome": "R-BTA-5661122", "name": "JMJD6 demethylates Me2R3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073398", "species_113671", "species_113685" ], "products": [ "species_10066894", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10066651": { "compartment": "compartment_7660", "id": "reaction_10066651", "reactome": "R-BTA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066642" ], "products": [ "species_10066644", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10073402": { "compartment": "compartment_7660", "id": "reaction_10073402", "reactome": "R-BTA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069756" ], "products": [ "species_10066642", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10069754": { "compartment": "compartment_7660", "id": "reaction_10069754", "reactome": "R-BTA-4754176", "name": "JMJD6 demethylates MeR3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066894", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10073404": { "compartment": "compartment_7660", "id": "reaction_10073404", "reactome": "R-BTA-5661124", "name": "JMJD6 demethylates MeR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070273", "species_113671", "species_113685" ], "products": [ "species_10035060", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000025492" ] }, "reaction_10073406": { "compartment": "compartment_7660", "id": "reaction_10073406", "reactome": "R-BTA-5661125", "name": "JMJD6 demethylates Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_113671", "species_113685" ], "products": [ "species_10070273", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000025492" ] }, "reaction_10069747": { "compartment": "compartment_7660", "id": "reaction_10069747", "reactome": "R-BTA-4724284", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069723" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10073394": { "compartment": "compartment_7660", "id": "reaction_10073394", "reactome": "R-BTA-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069811", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069721" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073396": { "compartment": "compartment_7660", "id": "reaction_10073396", "reactome": "R-BTA-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10072792" ], "products": [ "species_10069777", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10069719": { "compartment": "compartment_7660", "id": "reaction_10069719", "reactome": "R-BTA-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069712", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069769": { "compartment": "compartment_7660", "id": "reaction_10069769", "reactome": "R-BTA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10069756", "species_113685" ], "products": [ "species_10066642", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10073384": { "compartment": "compartment_7660", "id": "reaction_10073384", "reactome": "R-BTA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070949", "species_113671", "species_113685" ], "products": [ "species_29478", "species_10069756", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10069740": { "compartment": "compartment_7660", "id": "reaction_10069740", "reactome": "R-BTA-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073380": { "compartment": "compartment_7660", "id": "reaction_10073380", "reactome": "R-BTA-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10072735", "species_113685" ], "products": [ "species_10069712", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069796": { "compartment": "compartment_7660", "id": "reaction_10069796", "reactome": "R-BTA-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069777", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069785" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10073382": { "compartment": "compartment_7660", "id": "reaction_10073382", "reactome": "R-BTA-5661115", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10069937": { "compartment": "compartment_7660", "id": "reaction_10069937", "reactome": "R-BTA-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10066642" ], "modifiers": [ [ "species_10069934", "catalyst" ] ], "additional_components": [ "F1MUT0", "ENSBTAT00000004658", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072752": { "compartment": "compartment_7660", "id": "reaction_10072752", "reactome": "R-BTA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069712" ], "products": [ "species_77502", "species_10072735" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072755": { "compartment": "compartment_7660", "id": "reaction_10072755", "reactome": "R-BTA-5638332", "name": "PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069785" ], "modifiers": [ [ "species_10044337", "catalyst" ] ], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10069939": { "compartment": "compartment_7660", "id": "reaction_10069939", "reactome": "R-BTA-5159250", "name": "ATF7IP binds SETDB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069830", "species_10069834" ], "products": [ "species_10069836" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000107", "ENSBTAT00000086218", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10070962": { "compartment": "compartment_7660", "id": "reaction_10070962", "reactome": "R-BTA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069756" ], "products": [ "species_77502", "species_10070949" ], "modifiers": [ [ "species_10070959", "catalyst" ], [ "species_10070404", "inhibitor" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "G3X834", "ENSBTAT00000056084", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072725": { "compartment": "compartment_7660", "id": "reaction_10072725", "reactome": "R-BTA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066642" ], "products": [ "species_77502", "species_10069756" ], "modifiers": [ [ "species_10072722", "catalyst" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072788": { "compartment": "compartment_7660", "id": "reaction_10072788", "reactome": "R-BTA-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072771" ], "products": [ "species_77502", "species_10072786" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072823": { "compartment": "compartment_7660", "id": "reaction_10072823", "reactome": "R-BTA-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072800" ], "products": [ "species_77502", "species_10072821" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10069846": { "compartment": "compartment_7660", "id": "reaction_10069846", "reactome": "R-BTA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069712" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072790": { "compartment": "compartment_7660", "id": "reaction_10072790", "reactome": "R-BTA-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10072763" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072778": { "compartment": "compartment_7660", "id": "reaction_10072778", "reactome": "R-BTA-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072763" ], "products": [ "species_77502", "species_10072771" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072813": { "compartment": "compartment_7660", "id": "reaction_10072813", "reactome": "R-BTA-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10064889" ], "products": [ "species_77502", "species_10072800" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10072655": { "compartment": "compartment_70101", "id": "reaction_10072655", "reactome": "R-BTA-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10072636" ], "products": [ "species_10072642", "species_71285" ], "modifiers": [ [ "species_10072652", "catalyst" ] ], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "F1MTF1", "ENSBTAT00000025245" ] }, "reaction_10069838": { "compartment": "compartment_7660", "id": "reaction_10069838", "reactome": "R-BTA-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069721" ], "products": [ "species_77502", "species_10069811" ], "modifiers": [ [ "species_10069825", "catalyst" ], [ "species_10069836", "catalyst" ] ], "additional_components": [ "F1N6Y5", "ENSBTAT00000022553", "F1MXG0", "ENSBTAT00000009641", "A0A452DJ38", "ENSBTAT00000013472", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10072750": { "compartment": "compartment_7660", "id": "reaction_10072750", "reactome": "R-BTA-5638141", "name": "SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072735" ], "products": [ "species_77502", "species_10072743" ], "modifiers": [ [ "species_10072747", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084416" ] }, "reaction_10068699": { "compartment": "compartment_7660", "id": "reaction_10068699", "reactome": "R-BTA-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068694", "catalyst" ], [ "species_10068697", "inhibitor" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068844": { "compartment": "compartment_7660", "id": "reaction_10068844", "reactome": "R-BTA-3782637", "name": "HDAC8 deacetylates histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10044720", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000070733" ] }, "reaction_10091745": { "compartment": "compartment_7660", "id": "reaction_10091745", "reactome": "R-BTA-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068694", "species_9679795" ], "products": [ "species_10068697" ], "modifiers": [], "additional_components": [ "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068725": { "compartment": "compartment_7660", "id": "reaction_10068725", "reactome": "R-BTA-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068722", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "CHEBI:57627", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1MPA7", "ENSBTAT00000013888", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10068569": { "compartment": "compartment_7660", "id": "reaction_10068569", "reactome": "R-BTA-3662335", "name": "EP300 acetylates histone H2A, H2B, H3, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068132", "species_113560" ], "products": [ "species_2485002", "species_10068566" ], "modifiers": [ [ "species_10053052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021556" ] }, "reaction_10067596": { "compartment": "compartment_7660", "id": "reaction_10067596", "reactome": "R-BTA-3321883", "name": "MSL acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035060", "species_113560" ], "products": [ "species_2485002", "species_10067575" ], "modifiers": [ [ "species_10067593", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "F1MP98", "ENSBTAT00000013893", "F1MRF9", "ENSBTAT00000000991", "E1BFW0", "ENSBTAT00000030541" ] }, "reaction_10071886": { "compartment": "compartment_7660", "id": "reaction_10071886", "reactome": "R-BTA-5579018", "name": "NCOA1(868-1441) binds PAX3(1-319)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071878", "species_10071882" ], "products": [ "species_10071884" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064008", "ENSBTAT00000013131", "F1MTX0", "ENSBTAT00000013131", "G3N0C2", "ENSBTAT00000064008" ] }, "reaction_10070409": { "compartment": "compartment_7660", "id": "reaction_10070409", "reactome": "R-BTA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070394" ], "products": [ "species_77502", "species_10070404" ], "modifiers": [ [ "species_10070406", "catalyst" ] ], "additional_components": [ "A0A3Q1LQR4", "ENSBTAT00000066577", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070377": { "compartment": "compartment_7660", "id": "reaction_10070377", "reactome": "R-BTA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070328" ], "products": [ "species_77502", "species_10070374" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070520": { "compartment": "compartment_7660", "id": "reaction_10070520", "reactome": "R-BTA-5212679", "name": "DNMT3A binds Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_10044297" ], "products": [ "species_10070518" ], "modifiers": [], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000086443", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717" ] }, "reaction_10073416": { "compartment": "compartment_7660", "id": "reaction_10073416", "reactome": "R-BTA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070273" ], "products": [ "species_77502", "species_10073414" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070392": { "compartment": "compartment_7660", "id": "reaction_10070392", "reactome": "R-BTA-5205822", "name": "CARM1 methylates arginine-18 (H3R17) of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070379" ], "products": [ "species_77502", "species_10070389" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070282": { "compartment": "compartment_7660", "id": "reaction_10070282", "reactome": "R-BTA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10035060" ], "products": [ "species_77502", "species_10070273" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070896": { "compartment": "compartment_7660", "id": "reaction_10070896", "reactome": "R-BTA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070848" ], "products": [ "species_77502", "species_10070894" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070757": { "compartment": "compartment_7660", "id": "reaction_10070757", "reactome": "R-BTA-5229010", "name": "CARM1 methylates arginine-27 of histone H3 (H3R26)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070745" ], "products": [ "species_77502", "species_10070755" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070516": { "compartment": "compartment_7660", "id": "reaction_10070516", "reactome": "R-BTA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070467" ], "products": [ "species_77502", "species_10070513" ], "modifiers": [ [ "species_10066655", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068896" ] }, "reaction_10056383": { "compartment": "compartment_70101", "id": "reaction_10056383", "reactome": "R-BTA-1183128", "name": "PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1183111" ], "products": [ "species_29382", "species_1183191" ], "modifiers": [ [ "species_10056380", "catalyst" ] ], "additional_components": [ "species_74016", "A6QLC1", "ENSBTAT00000015977", "F1N048", "ENSBTAT00000004411", "E1BD46", "ENSBTAT00000015978", "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10066966": { "compartment": "compartment_7660", "id": "reaction_10066966", "reactome": "R-BTA-3247569", "name": "PADI4 deiminates Histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066920" ], "products": [ "species_10066951", "species_76230" ], "modifiers": [ [ "species_10066963", "catalyst" ] ], "additional_components": [ "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10092108": { "compartment": "compartment_24337", "id": "reaction_10092108", "reactome": "R-BTA-9705738", "name": "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092095", "species_10092091" ], "products": [ "species_10051733", "species_10055212", "species_10055148", "species_10055146", "species_10055162", "species_10092105" ], "modifiers": [ [ "species_10092091", "catalyst" ] ], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "ENSBTAT00000002831", "ENSBTAT00000026036", "ENSBTAT00000078734", "ENSBTAT00000068692", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831" ] }, "reaction_10092257": { "compartment": "compartment_24337", "id": "reaction_10092257", "reactome": "R-BTA-9707977", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092105" ], "products": [ "species_10092255" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10073690": { "compartment": "compartment_876", "id": "reaction_10073690", "reactome": "R-BTA-5668414", "name": "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10073673" ], "products": [ "species_10073687" ], "modifiers": [ [ "species_10073673", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074280": { "compartment": "compartment_876", "id": "reaction_10074280", "reactome": "R-BTA-5675948", "name": "TNFRSF6B binds TNFSF6,14,15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074276", "species_10074270" ], "products": [ "species_10074278" ], "modifiers": [], "additional_components": [ "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452", "ENSBTAT00000028109", "A6QPW7", "ENSBTAT00000028109", "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10074266": { "compartment": "compartment_876", "id": "reaction_10074266", "reactome": "R-BTA-5675947", "name": "TNFSF18 binds TNFRSF18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074262", "species_10074258" ], "products": [ "species_10074264" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064406", "ENSBTAT00000079425", "A0A3Q1M9X1", "ENSBTAT00000079425", "Q08DT5", "ENSBTAT00000064406" ] }, "reaction_10076237": { "compartment": "compartment_876", "id": "reaction_10076237", "reactome": "R-BTA-5693012", "name": "TNFSF15 binds TNFRSF25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074274", "species_10076233" ], "products": [ "species_10076235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036452", "ENSBTAT00000085571", "A0A3Q1LIC4", "ENSBTAT00000085571", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10073765": { "compartment": "compartment_876", "id": "reaction_10073765", "reactome": "R-BTA-5669035", "name": "TNFSF11 binds TNFRSF11A, B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073761" ], "products": [ "species_10073763" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009759", "A5D7R1", "ENSBTAT00000009759", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10076165": { "compartment": "compartment_876", "id": "reaction_10076165", "reactome": "R-BTA-5692315", "name": "OX40L binds OX40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076161", "species_10076155" ], "products": [ "species_10076163" ], "modifiers": [], "additional_components": [ "E1BGY4", "ENSBTAT00000003763", "ENSBTAT00000066801", "A0A3Q1M5M3", "ENSBTAT00000066801", "E1BGY4", "ENSBTAT00000003763" ] }, "reaction_10074340": { "compartment": "compartment_876", "id": "reaction_10074340", "reactome": "R-BTA-5676607", "name": "sBAFF,sAPRIL binds TACI,BCMA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074326", "species_10074336" ], "products": [ "species_10074338" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10074312": { "compartment": "compartment_876", "id": "reaction_10074312", "reactome": "R-BTA-5676593", "name": "TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073669", "species_10073585" ], "products": [ "species_10073671" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074314": { "compartment": "compartment_876", "id": "reaction_10074314", "reactome": "R-BTA-5676595", "name": "TRAFs bind RANK:RANKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073623", "species_10073585" ], "products": [ "species_10073625" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073757": { "compartment": "compartment_876", "id": "reaction_10073757", "reactome": "R-BTA-5669023", "name": "TWEAK binds FN14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073601", "species_10073597" ], "products": [ "species_10073603" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081383", "F1MX43", "ENSBTAT00000045584", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074316": { "compartment": "compartment_876", "id": "reaction_10074316", "reactome": "R-BTA-5676596", "name": "TRAF3 binds BAFFR:BAFF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073637", "species_10073585" ], "products": [ "species_10073639" ], "modifiers": [], "additional_components": [ "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074318": { "compartment": "compartment_876", "id": "reaction_10074318", "reactome": "R-BTA-5676598", "name": "TRAF2:cIAP1/2 complex binds FN14:TWEAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073603", "species_10073585" ], "products": [ "species_10073605" ], "modifiers": [], "additional_components": [ "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074320": { "compartment": "compartment_876", "id": "reaction_10074320", "reactome": "R-BTA-5676599", "name": "sBAFF trimer binds BAFFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073635", "species_10073629" ], "products": [ "species_10073637" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "ENSBTAT00000037660", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074306": { "compartment": "compartment_876", "id": "reaction_10074306", "reactome": "R-BTA-5676589", "name": "RANKL,sRANKL trimer binds RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073609" ], "products": [ "species_10074304" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10074308": { "compartment": "compartment_876", "id": "reaction_10074308", "reactome": "R-BTA-5676591", "name": "2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073667", "species_10073643" ], "products": [ "species_10073669" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "ENSBTAT00000020355", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074310": { "compartment": "compartment_876", "id": "reaction_10074310", "reactome": "R-BTA-5676592", "name": "2xRANK binds RANKL,sRANKL trimer:RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074304", "species_10073609" ], "products": [ "species_10073623" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073699": { "compartment": "compartment_876", "id": "reaction_10073699", "reactome": "R-BTA-5668454", "name": "K63polyUb-cIAP1,2 ubiquitinates TRAF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073687", "species_10052288" ], "products": [ "species_10073696" ], "modifiers": [ [ "species_10073687", "catalyst" ] ], "additional_components": [ "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10071948": { "compartment": "compartment_70101", "id": "reaction_10071948", "reactome": "R-BTA-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524" ], "products": [ "species_10047524" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10073708": { "compartment": "compartment_70101", "id": "reaction_10073708", "reactome": "R-BTA-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_29370", "species_10073705" ], "modifiers": [ [ "species_10047524", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10071982": { "compartment": "compartment_70101", "id": "reaction_10071982", "reactome": "R-BTA-5607726", "name": "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071979" ], "products": [ "species_29370", "species_10071971" ], "modifiers": [ [ "species_10071979", "catalyst" ] ], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316" ] }, "reaction_10072030": { "compartment": "compartment_7660", "id": "reaction_10072030", "reactome": "R-BTA-5607741", "name": "p52:RELB translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071991" ], "products": [ "species_10072028" ], "modifiers": [], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "F1MBB0", "ENSBTAT00000055496", "A7MBB7", "ENSBTAT00000007904" ] }, "reaction_10071975": { "compartment": "compartment_70101", "id": "reaction_10071975", "reactome": "R-BTA-5607723", "name": "SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10071971" ], "products": [ "species_10071973" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10057834": { "compartment": "compartment_70101", "id": "reaction_10057834", "reactome": "R-BTA-1370500", "name": "PRLR binds SCF beta-TrCP complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10054520" ], "products": [ "species_10054522" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10054524": { "compartment": "compartment_984", "id": "reaction_10054524", "reactome": "R-BTA-976991", "name": "Prolactin receptor ligands bind the prolactin receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054501", "species_10054509" ], "products": [ "species_10054511" ], "modifiers": [ [ "species_10054522", "inhibitor" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10060412": { "compartment": "compartment_876", "id": "reaction_10060412", "reactome": "R-BTA-1671687", "name": "PRLR activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054511" ], "products": [ "species_10054511" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10057836": { "compartment": "compartment_876", "id": "reaction_10057836", "reactome": "R-BTA-1370505", "name": "PRLR is phosphorylated at Ser-349", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054520" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057823": { "compartment": "compartment_876", "id": "reaction_10057823", "reactome": "R-BTA-1364044", "name": "PRLR:JAK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054507" ], "products": [ "species_10054509" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10056335": { "compartment": "compartment_876", "id": "reaction_10056335", "reactome": "R-BTA-1170539", "name": "Prolactin receptor is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054522" ], "products": [ "species_10043873", "species_10056333" ], "modifiers": [], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10054791": { "compartment": "compartment_876", "id": "reaction_10054791", "reactome": "R-BTA-982810", "name": "JAK2 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054785" ], "modifiers": [ [ "species_10054789", "catalyst" ] ], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10054779": { "compartment": "compartment_984", "id": "reaction_10054779", "reactome": "R-BTA-982765", "name": "Growth hormone forms dimers and oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048427" ], "products": [ "species_10054777" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082606", "A0A3Q1LZG1", "ENSBTAT00000082606" ] }, "reaction_10056268": { "compartment": "compartment_876", "id": "reaction_10056268", "reactome": "R-BTA-1169192", "name": "PTP1B dephosphorylates GHR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10056255" ], "products": [ "species_29372", "species_10056265" ], "modifiers": [ [ "species_10056255", "catalyst" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678", "A6QQN2", "ENSBTAT00000008678", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090844": { "compartment": "compartment_876", "id": "reaction_10090844", "reactome": "R-BTA-9604767", "name": "FLT3LG dimer:FLT3 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084303" ], "products": [ "species_29370", "species_10036552" ], "modifiers": [ [ "species_10084303", "catalyst" ], [ "species_10090842", "inhibitor" ], [ "species_10090840", "inhibitor" ] ], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092151": { "compartment": "compartment_876", "id": "reaction_10092151", "reactome": "R-BTA-9706336", "name": "Active FLT3 binds to SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10036552" ], "products": [ "species_10092149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10092159": { "compartment": "compartment_876", "id": "reaction_10092159", "reactome": "R-BTA-9706344", "name": "FLT3 phosphorylates GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092135", "species_113592" ], "products": [ "species_29370", "species_10092156" ], "modifiers": [ [ "species_10092135", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10077790": { "compartment": "compartment_876", "id": "reaction_10077790", "reactome": "R-BTA-6786789", "name": "FLT3LG dimer binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036540", "species_10077786" ], "products": [ "species_10077788" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10084305": { "compartment": "compartment_876", "id": "reaction_10084305", "reactome": "R-BTA-8854736", "name": "FLT3LG dimer:FLT3 binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077788", "species_10077786" ], "products": [ "species_10084303" ], "modifiers": [], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10092040": { "compartment": "compartment_876", "id": "reaction_10092040", "reactome": "R-BTA-9698408", "name": "PTPRJ dephosphorylates active FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036552" ], "products": [ "species_10092037", "species_29372" ], "modifiers": [ [ "species_10080697", "catalyst" ], [ "species_29408", "inhibitor" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "ENSBTAT00000081330" ] }, "reaction_10092139": { "compartment": "compartment_876", "id": "reaction_10092139", "reactome": "R-BTA-9706315", "name": "Active FLT3 binds to SH2B3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055924", "species_10036552" ], "products": [ "species_10092112" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079236", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092173": { "compartment": "compartment_876", "id": "reaction_10092173", "reactome": "R-BTA-9706350", "name": "FLT3 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10092110" ], "products": [ "species_29370", "species_10092170" ], "modifiers": [ [ "species_10092110", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092141": { "compartment": "compartment_876", "id": "reaction_10092141", "reactome": "R-BTA-9706319", "name": "Active FLT3 binds to SLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092116", "species_10036552" ], "products": [ "species_10092118" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400" ] }, "reaction_10092143": { "compartment": "compartment_876", "id": "reaction_10092143", "reactome": "R-BTA-9706323", "name": "Active FLT3 binds to SLA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092122", "species_10036552" ], "products": [ "species_10092124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137" ] }, "reaction_10092126": { "compartment": "compartment_876", "id": "reaction_10092126", "reactome": "R-BTA-9706293", "name": "Active FLT3 binds to CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10036552" ], "products": [ "species_10092110" ], "modifiers": [ [ "species_10092118", "catalyst" ], [ "species_10092124", "catalyst" ], [ "species_10092112", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092147": { "compartment": "compartment_876", "id": "reaction_10092147", "reactome": "R-BTA-9706330", "name": "Active FLT3 binds to SOCS6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087926", "species_10036552" ], "products": [ "species_10092145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023144", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKN8", "ENSBTAT00000023144" ] }, "reaction_10092195": { "compartment": "compartment_876", "id": "reaction_10092195", "reactome": "R-BTA-9706364", "name": "Internalization of ubiquitinated FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092178" ], "products": [ "species_10092193" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092183": { "compartment": "compartment_876", "id": "reaction_10092183", "reactome": "R-BTA-9706354", "name": "Ubiquitination of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10036552" ], "products": [ "species_10092178" ], "modifiers": [ [ "species_10092180", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092137": { "compartment": "compartment_876", "id": "reaction_10092137", "reactome": "R-BTA-9706308", "name": "Active FLT3 binds to GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10036552" ], "products": [ "species_10092135" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10092043": { "compartment": "compartment_70101", "id": "reaction_10092043", "reactome": "R-BTA-9699578", "name": "Active FLT3 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499", "species_113592" ], "products": [ "species_29370", "species_10083560" ], "modifiers": [ [ "species_10036552", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092033": { "compartment": "compartment_876", "id": "reaction_10092033", "reactome": "R-BTA-9698170", "name": "Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036565", "species_10035515" ], "products": [ "species_10065275" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10092133": { "compartment": "compartment_876", "id": "reaction_10092133", "reactome": "R-BTA-9706304", "name": "Active FLT3 binds to GRAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046947", "species_10036552" ], "products": [ "species_10092131" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020161", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKA6", "ENSBTAT00000020161" ] }, "reaction_10092165": { "compartment": "compartment_876", "id": "reaction_10092165", "reactome": "R-BTA-9706345", "name": "Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092161", "species_10035515" ], "products": [ "species_10092163" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "P32871", "ENSBTAT00000072391", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10090916": { "compartment": "compartment_70101", "id": "reaction_10090916", "reactome": "R-BTA-9607301", "name": "Active FLT3:GRB2 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10036554" ], "products": [ "species_10074033" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10090919": { "compartment": "compartment_70101", "id": "reaction_10090919", "reactome": "R-BTA-9607304", "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074033", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10052217": { "compartment": "compartment_70101", "id": "reaction_10052217", "reactome": "R-BTA-909726", "name": "Phosphorylation of STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052144", "species_113592", "species_10051758" ], "products": [ "species_10052194", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ], [ "species_10047046", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10052347": { "compartment": "compartment_13231", "id": "reaction_10052347", "reactome": "R-BTA-913529", "name": "Translocation of p-STAT1:p-STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10052189": { "compartment": "compartment_13231", "id": "reaction_10052189", "reactome": "R-BTA-909721", "name": "Translocation of ISGF3 complex to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052169" ], "products": [ "species_10052181" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "Q58DC4", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10055946": { "compartment": "compartment_70101", "id": "reaction_10055946", "reactome": "R-BTA-997309", "name": "Dephosphorylation of STAT1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052194" ], "products": [ "species_10055943", "species_29372" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000002653" ] }, "reaction_10055955": { "compartment": "compartment_70101", "id": "reaction_10055955", "reactome": "R-BTA-997311", "name": "Dephosphorylation of TYK2 by PTP1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052222" ], "products": [ "species_29372", "species_10055948" ], "modifiers": [ [ "species_10055952", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000008678" ] }, "reaction_10055958": { "compartment": "compartment_70101", "id": "reaction_10055958", "reactome": "R-BTA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10055948" ], "products": [ "species_29372", "species_10052206" ], "modifiers": [ [ "species_10043836", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000077529" ] }, "reaction_10052159": { "compartment": "compartment_70101", "id": "reaction_10052159", "reactome": "R-BTA-909719", "name": "Recruitment of STAT2 to p-IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052140", "species_10052153" ], "products": [ "species_10052157" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10070719": { "compartment": "compartment_5460", "id": "reaction_10070719", "reactome": "R-BTA-5223305", "name": "ABCE1 binds RNASEL, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070711", "species_10070715" ], "products": [ "species_10070717" ], "modifiers": [], "additional_components": [ "A5H027", "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10052147": { "compartment": "compartment_70101", "id": "reaction_10052147", "reactome": "R-BTA-909718", "name": "Formation of p-STAT1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051758" ], "products": [ "species_10051766", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052210": { "compartment": "compartment_876", "id": "reaction_10052210", "reactome": "R-BTA-909724", "name": "Recruitment of IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052204", "species_10052200" ], "products": [ "species_10052206" ], "modifiers": [ [ "species_10052208", "inhibitor" ] ], "additional_components": [ "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052213": { "compartment": "compartment_70101", "id": "reaction_10052213", "reactome": "R-BTA-909725", "name": "Interaction of IRF9 with p-STAT2:p-STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052167", "species_10052163" ], "products": [ "species_10052169" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10052233": { "compartment": "compartment_70101", "id": "reaction_10052233", "reactome": "R-BTA-909730", "name": "Phosphorylation of INFAR1 by TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052222" ], "products": [ "species_29370", "species_10052153" ], "modifiers": [ [ "species_10052222", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10091725": { "compartment": "compartment_70101", "id": "reaction_10091725", "reactome": "R-BTA-9678737", "name": "IFNAR1:TYK2 binds TYK2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678619", "species_10052200" ], "products": [ "species_10052208" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052236": { "compartment": "compartment_70101", "id": "reaction_10052236", "reactome": "R-BTA-909732", "name": "Phosphorylation of STAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052157" ], "products": [ "species_29370", "species_10052144" ], "modifiers": [ [ "species_10052157", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052229": { "compartment": "compartment_70101", "id": "reaction_10052229", "reactome": "R-BTA-909729", "name": "Activation of JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052206" ], "products": [ "species_29370", "species_10052222" ], "modifiers": [ [ "species_10052206", "catalyst" ], [ "species_10052227", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052196": { "compartment": "compartment_70101", "id": "reaction_10052196", "reactome": "R-BTA-909722", "name": "Release of p-STAT2:p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052194" ], "products": [ "species_10052167", "species_10052153" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10056297": { "compartment": "compartment_70101", "id": "reaction_10056297", "reactome": "R-BTA-1169405", "name": "ISGylation of protein phosphatase 1 beta (PP2CB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056293", "species_113592" ], "products": [ "species_111294", "species_10056295", "species_10056276", "species_10053116", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000050064", "O02741", "ENSBTAT00000019573", "O62830", "ENSBTAT00000050064", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056315": { "compartment": "compartment_70101", "id": "reaction_10056315", "reactome": "R-BTA-1169406", "name": "ISGylation of host proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056311", "species_113592" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_76577", "species_10056313" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056283": { "compartment": "compartment_70101", "id": "reaction_10056283", "reactome": "R-BTA-1169394", "name": "ISGylation of IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10039246" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056280", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000031869", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "Q4JF28", "ENSBTAT00000031869", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060730": { "compartment": "compartment_70101", "id": "reaction_10060730", "reactome": "R-BTA-1678842", "name": "Competitive inhibition of translation initiation by ISGylated 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060726", "species_10060706" ], "products": [ "species_10060724", "species_10060728" ], "modifiers": [], "additional_components": [ "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060732": { "compartment": "compartment_70101", "id": "reaction_10060732", "reactome": "R-BTA-1678843", "name": "ISGylation of protein translation regulator 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10060704" ], "products": [ "species_10060706" ], "modifiers": [], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056287": { "compartment": "compartment_70101", "id": "reaction_10056287", "reactome": "R-BTA-1169402", "name": "ISGylation of E2 conjugating enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10055358" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056285", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000084854", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A3Q1MAR8", "ENSBTAT00000084854", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056289": { "compartment": "compartment_70101", "id": "reaction_10056289", "reactome": "R-BTA-1169403", "name": "Interaction of E3 ligase with ISG15:E2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056276", "species_10056270" ], "products": [ "species_10056278" ], "modifiers": [], "additional_components": [ "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060694": { "compartment": "compartment_70101", "id": "reaction_10060694", "reactome": "R-BTA-1678841", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056313" ], "products": [ "species_10056311", "species_141681" ], "modifiers": [ [ "species_10060689", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000086230" ] }, "reaction_10089341": { "compartment": "compartment_70101", "id": "reaction_10089341", "reactome": "R-BTA-8985153", "name": "OASL binds DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10089337" ], "products": [ "species_10089339" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "ENSBTAT00000004270", "F1MXX7", "ENSBTAT00000004270", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10089696": { "compartment": "compartment_70101", "id": "reaction_10089696", "reactome": "R-BTA-9009936", "name": "RNASEL cleaves cellular ssRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_170292" ], "products": [ "species_9009945" ], "modifiers": [ [ "species_10089693", "catalyst" ] ], "additional_components": [ "A5H027", "ENSBTAT00000044248", "species_113592" ] }, "reaction_10089349": { "compartment": "compartment_70101", "id": "reaction_10089349", "reactome": "R-BTA-8985201", "name": "ABCE1 binds RNASEL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089345", "species_10089343" ], "products": [ "species_10089347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10089703": { "compartment": "compartment_70101", "id": "reaction_10089703", "reactome": "R-BTA-9009950", "name": "PDE12 cleaves 2'-5' oligoadenylates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8983696" ], "products": [ "species_70106", "species_113592", "species_76577" ], "modifiers": [ [ "species_10089700", "catalyst" ] ], "additional_components": [ "species_113592", "ENSBTAT00000020675" ] }, "reaction_10057588": { "compartment": "compartment_876", "id": "reaction_10057588", "reactome": "R-BTA-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057585", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ50", "ENSBTAT00000074252", "E1BGH7", "ENSBTAT00000011399", "F1MLI5", "ENSBTAT00000025779" ] }, "reaction_10091423": { "compartment": "compartment_70101", "id": "reaction_10091423", "reactome": "R-BTA-9647643", "name": "GSDMD (1-275) binds bacterial cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647661", "species_10037243" ], "products": [ "species_10091421" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092350": { "compartment": "compartment_70101", "id": "reaction_10092350", "reactome": "R-BTA-9710106", "name": "ELANE cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10092343", "species_10092345" ], "modifiers": [ [ "species_10092347", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000064480" ] }, "reaction_10091409": { "compartment": "compartment_876", "id": "reaction_10091409", "reactome": "R-BTA-9647619", "name": "GSDMD forms ringshaped oligomers ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081899" ], "products": [ "species_10081901" ], "modifiers": [ [ "species_10052773", "inhibitor" ], [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000087110" ] }, "reaction_10081905": { "compartment": "compartment_984", "id": "reaction_10081905", "reactome": "R-BTA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044670" ], "products": [ "species_10081502" ], "modifiers": [ [ "species_10081901", "catalyst" ], [ "species_10081903", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024094", "ENSBTAT00000024094", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092341": { "compartment": "compartment_70101", "id": "reaction_10092341", "reactome": "R-BTA-9710101", "name": "CASP4, CASP5 cleave GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10092338", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "O75601", "ENSBTAT00000027820" ] }, "reaction_10091415": { "compartment": "compartment_70101", "id": "reaction_10091415", "reactome": "R-BTA-9647631", "name": "GSDMD (1-275) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037243" ], "products": [ "species_10091413" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10091439": { "compartment": "compartment_70101", "id": "reaction_10091439", "reactome": "R-BTA-9647680", "name": "CASP1 cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10050026", "catalyst" ], [ "species_10091437", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "A0A3Q1MFA5", "ENSBTAT00000072083", "ENSBTAT00000087110" ] }, "reaction_10091425": { "compartment": "compartment_70101", "id": "reaction_10091425", "reactome": "R-BTA-9647645", "name": "GSDMD oligomerizes into arc-, slit-shaped structures", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091413", "species_10037243" ], "products": [ "species_10081899" ], "modifiers": [ [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110" ] }, "reaction_10092352": { "compartment": "compartment_70101", "id": "reaction_10092352", "reactome": "R-BTA-9710254", "name": "GSDME oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091427", "species_10037249" ], "products": [ "species_10081903" ], "modifiers": [], "additional_components": [ "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092354": { "compartment": "compartment_70101", "id": "reaction_10092354", "reactome": "R-BTA-9710263", "name": "GZMB cleaves GSDME", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091417" ], "products": [ "species_10037249", "species_10091419" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000013262" ] }, "reaction_10091429": { "compartment": "compartment_70101", "id": "reaction_10091429", "reactome": "R-BTA-9647660", "name": "GSDME (1-270) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037249" ], "products": [ "species_10091427" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10037253": { "compartment": "compartment_17906", "id": "reaction_10037253", "reactome": "R-BTA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037239" ], "products": [ "species_10037211" ], "modifiers": [ [ "species_10037235", "catalyst" ], [ "species_10037245", "catalyst" ], [ "species_10037251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q05KI7", "ENSBTAT00000000549", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10092356": { "compartment": "compartment_70101", "id": "reaction_10092356", "reactome": "R-BTA-9710353", "name": "GSDMD (1-275) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037243" ], "products": [ "species_10037245" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092358": { "compartment": "compartment_70101", "id": "reaction_10092358", "reactome": "R-BTA-9710354", "name": "GSDME (1-270) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037249" ], "products": [ "species_10037251" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10091817": { "compartment": "compartment_70101", "id": "reaction_10091817", "reactome": "R-BTA-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10039151" ], "products": [ "species_10091815" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10056239": { "compartment": "compartment_876", "id": "reaction_10056239", "reactome": "R-BTA-1168636", "name": "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10056236", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LSU3", "ENSBTAT00000068365", "E1BG59", "ENSBTAT00000029159", "species_6797635" ] }, "reaction_10044568": { "compartment": "compartment_7660", "id": "reaction_10044568", "reactome": "R-BTA-264865", "name": "Caspase-mediated cleavage of Lamin A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044551" ], "products": [ "species_10044555", "species_10044553" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023373", "ENSBTAT00000023373", "ENSBTAT00000023373", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10090575": { "compartment": "compartment_13231", "id": "reaction_10090575", "reactome": "R-BTA-9029690", "name": "Caspase-6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044753" ], "products": [ "species_10044565" ], "modifiers": [], "additional_components": [ "G3X702", "ENSBTAT00000016642", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044578": { "compartment": "compartment_7660", "id": "reaction_10044578", "reactome": "R-BTA-264871", "name": "Caspase-mediated cleavage of Lamin B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044572" ], "products": [ "species_10044576", "species_10044574" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075973", "ENSBTAT00000075973", "ENSBTAT00000075973", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10036080": { "compartment": "compartment_7660", "id": "reaction_10036080", "reactome": "R-BTA-77586", "name": "Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036074" ], "products": [ "species_10036078", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1N0Z1", "ENSBTAT00000074628", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10036915": { "compartment": "compartment_7660", "id": "reaction_10036915", "reactome": "R-BTA-111437", "name": "Cleavage of the 3'-end of the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036911" ], "products": [ "species_10036913", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10083967": { "compartment": "compartment_876", "id": "reaction_10083967", "reactome": "R-BTA-8852010", "name": "BTNL2 binds activated T cells surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083963" ], "products": [ "species_10083965" ], "modifiers": [], "additional_components": [ "ENSBTAT00000049415", "A6QNP4", "ENSBTAT00000049415" ] }, "reaction_10083959": { "compartment": "compartment_876", "id": "reaction_10083959", "reactome": "R-BTA-8851988", "name": "BTN2A2 binds T cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083955" ], "products": [ "species_10083957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045031", "F1MZI6", "ENSBTAT00000045031" ] }, "reaction_10046811": { "compartment": "compartment_876", "id": "reaction_10046811", "reactome": "R-BTA-388811", "name": "CD28 homodimer binds B7-1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046779", "species_10046793" ], "products": [ "species_10046809" ], "modifiers": [], "additional_components": [ "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1ND77", "ENSBTAT00000079588" ] }, "reaction_10046907": { "compartment": "compartment_70101", "id": "reaction_10046907", "reactome": "R-BTA-388831", "name": "Phosphorylation of CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037459", "species_113592", "species_10046905" ], "products": [ "species_10046818", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015730", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10047530": { "compartment": "compartment_70101", "id": "reaction_10047530", "reactome": "R-BTA-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_10047527", "species_29370" ], "modifiers": [ [ "species_10047008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000080762" ] }, "reaction_10046932": { "compartment": "compartment_70101", "id": "reaction_10046932", "reactome": "R-BTA-389158", "name": "CD28 bound PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10046929", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046787": { "compartment": "compartment_876", "id": "reaction_10046787", "reactome": "R-BTA-388808", "name": "CD28 homodimer binds B7-2 monomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046783", "species_10046779" ], "products": [ "species_10046785" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1MLL9", "ENSBTAT00000081673" ] }, "reaction_10046943": { "compartment": "compartment_70101", "id": "reaction_10046943", "reactome": "R-BTA-389354", "name": "Activation of Vav1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10046936" ], "products": [ "species_29370", "species_10046940" ], "modifiers": [ [ "species_10037459", "catalyst" ] ], "additional_components": [ "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000015730" ] }, "reaction_10046822": { "compartment": "compartment_70101", "id": "reaction_10046822", "reactome": "R-BTA-388814", "name": "Grb2 binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10035485" ], "products": [ "species_10046820" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046951": { "compartment": "compartment_70101", "id": "reaction_10046951", "reactome": "R-BTA-389381", "name": "Gads binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10046947" ], "products": [ "species_10046949" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000020161", "E1BKA6", "ENSBTAT00000020161", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046834": { "compartment": "compartment_876", "id": "reaction_10046834", "reactome": "R-BTA-388817", "name": "ICOS binds ICOSL/B7-H2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046830", "species_10046826" ], "products": [ "species_10046832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019810", "ENSBTAT00000028775", "Q58DF9", "ENSBTAT00000028775", "E1BCU8", "ENSBTAT00000019810" ] }, "reaction_10046909": { "compartment": "compartment_70101", "id": "reaction_10046909", "reactome": "R-BTA-388833", "name": "Phosphorylation of CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046805", "species_113592", "species_10043788" ], "products": [ "species_29370", "species_10046899", "species_10041566" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10046959": { "compartment": "compartment_70101", "id": "reaction_10046959", "reactome": "R-BTA-389532", "name": "PP2A binds CTLA4 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046801", "species_10041566" ], "products": [ "species_10046803" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046807": { "compartment": "compartment_876", "id": "reaction_10046807", "reactome": "R-BTA-388809", "name": "CTLA-4 binds B7-1/B7-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046803", "species_10046795" ], "products": [ "species_10046805" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046903": { "compartment": "compartment_70101", "id": "reaction_10046903", "reactome": "R-BTA-388829", "name": "SHP2 phosphatase binds CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10046899" ], "products": [ "species_10046901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10075923": { "compartment": "compartment_876", "id": "reaction_10075923", "reactome": "R-BTA-5690669", "name": "CD22 binds itself to form homo-oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075919" ], "products": [ "species_10075921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081458", "A0A3Q1NI55", "ENSBTAT00000081458" ] }, "reaction_10065019": { "compartment": "compartment_453088", "id": "reaction_10065019", "reactome": "R-BTA-2213241", "name": "Formation of nonameric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065015", "species_10064164" ], "products": [ "species_10065017" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178" ] }, "reaction_10064219": { "compartment": "compartment_161320", "id": "reaction_10064219", "reactome": "R-BTA-2130504", "name": "Cleavage of lip22 to lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063931" ], "products": [ "species_10063937" ], "modifiers": [ [ "species_10064216", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "P25326", "ENSBTAT00000022774" ] }, "reaction_10065051": { "compartment": "compartment_161320", "id": "reaction_10065051", "reactome": "R-BTA-2213244", "name": "Loading of antigenic peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065047", "species_2213226" ], "products": [ "species_10065045", "species_10065049" ], "modifiers": [], "additional_components": [ "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10065021": { "compartment": "compartment_20699", "id": "reaction_10065021", "reactome": "R-BTA-2213243", "name": "Fusion of COPII vesicle with Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064275" ], "products": [ "species_10064116", "species_10064225" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064221": { "compartment": "compartment_161320", "id": "reaction_10064221", "reactome": "R-BTA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10065055": { "compartment": "compartment_17938", "id": "reaction_10065055", "reactome": "R-BTA-2213246", "name": "Disassociation of CLIP from MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065045", "species_10063941" ], "products": [ "species_10065047", "species_10065053" ], "modifiers": [], "additional_components": [ "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "ENSBTAT00000074178" ] }, "reaction_10065009": { "compartment": "compartment_24337", "id": "reaction_10065009", "reactome": "R-BTA-2213235", "name": "Trafficking of nonameric complex in the endocytic pathway", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065007" ], "products": [ "species_10063925" ], "modifiers": [], "additional_components": [ "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1ML60", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1N610", "ENSBTAT00000026100", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10084401": { "compartment": "compartment_876", "id": "reaction_10084401", "reactome": "R-BTA-8856157", "name": "LAG3 (CD233) binds MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064210", "species_10084397" ], "products": [ "species_10084399" ], "modifiers": [], "additional_components": [ "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "ENSBTAT00000077596", "A0A3Q1LYZ8", "ENSBTAT00000077596", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10065011": { "compartment": "compartment_453088", "id": "reaction_10065011", "reactome": "R-BTA-2213239", "name": "Formation of MHC II alpha beta heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064162", "species_10064138" ], "products": [ "species_10064164" ], "modifiers": [], "additional_components": [ "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064277": { "compartment": "compartment_13959", "id": "reaction_10064277", "reactome": "R-BTA-2130731", "name": "Formation of COPII vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064225", "species_10064223" ], "products": [ "species_10064275" ], "modifiers": [], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064118": { "compartment": "compartment_263163", "id": "reaction_10064118", "reactome": "R-BTA-2130393", "name": "Transport of MHC II:Ii complex along Golgi to TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064116" ], "products": [ "species_10064020" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064214": { "compartment": "compartment_876", "id": "reaction_10064214", "reactome": "R-BTA-2130500", "name": "Insertion of MHC II:Ii complex in to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064066" ], "products": [ "species_10064212" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064068": { "compartment": "compartment_13946", "id": "reaction_10064068", "reactome": "R-BTA-2130378", "name": "Transport of MHC II:Ii complex to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064020" ], "products": [ "species_10064066" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072" ] }, "reaction_10063972": { "compartment": "compartment_161320", "id": "reaction_10063972", "reactome": "R-BTA-2130349", "name": "Generation of CLIP from lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063937" ], "products": [ "species_10063941" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10042635": { "compartment": "compartment_876", "id": "reaction_10042635", "reactome": "R-BTA-199154", "name": "CD200 binds to CD200R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042631", "species_10042627" ], "products": [ "species_10042633" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027169", "ENSBTAT00000001635", "A5D7V5", "ENSBTAT00000001635", "Q3ZC60", "ENSBTAT00000027169" ] }, "reaction_10042253": { "compartment": "compartment_876", "id": "reaction_10042253", "reactome": "R-BTA-199032", "name": "MADCAM1-1 binds Integrin alpha4beta7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042245", "species_10042249" ], "products": [ "species_10042251" ], "modifiers": [], "additional_components": [ "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279", "ENSBTAT00000068738", "A0A3Q1MBF2", "ENSBTAT00000068738", "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279" ] }, "reaction_10042623": { "compartment": "compartment_876", "id": "reaction_10042623", "reactome": "R-BTA-199112", "name": "CRTAM binds to NECL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042615", "species_10042619" ], "products": [ "species_10042621" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076490", "ENSBTAT00000083396", "A0A3Q1M4X8", "ENSBTAT00000083396", "A7YWT5", "ENSBTAT00000076490" ] }, "reaction_10042129": { "compartment": "compartment_876", "id": "reaction_10042129", "reactome": "R-BTA-198955", "name": "TCR complex interacts with peptide antigen-presenting MHC Class I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042125", "species_10042061" ], "products": [ "species_10042127" ], "modifiers": [], "additional_components": [ "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046" ] }, "reaction_10074993": { "compartment": "compartment_876", "id": "reaction_10074993", "reactome": "R-BTA-5685607", "name": "Sialic acid binds SIGLEC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006168", "species_10074989" ], "products": [ "species_10074991" ], "modifiers": [], "additional_components": [ "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "species_1006168" ] }, "reaction_10075009": { "compartment": "compartment_876", "id": "reaction_10075009", "reactome": "R-BTA-5685608", "name": "CLEC2B binds KLRF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074999", "species_10075005" ], "products": [ "species_10075007" ], "modifiers": [], "additional_components": [ "A5PJG8", "ENSBTAT00000042955", "A0A3Q1NBN7", "ENSBTAT00000082969", "A0A3Q1NBN7", "ENSBTAT00000082969", "A5PJG8", "ENSBTAT00000042955" ] }, "reaction_10084672": { "compartment": "compartment_876", "id": "reaction_10084672", "reactome": "R-BTA-8862090", "name": "PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084640", "species_10084668" ], "products": [ "species_10084670" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001412", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "F1MJX3", "ENSBTAT00000001412" ] }, "reaction_10074899": { "compartment": "compartment_876", "id": "reaction_10074899", "reactome": "R-BTA-5685603", "name": "SAP and EAT2 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074895", "species_10074889" ], "products": [ "species_10074897" ], "modifiers": [], "additional_components": [ "F1MLN1", "ENSBTAT00000034482", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10076963": { "compartment": "compartment_876", "id": "reaction_10076963", "reactome": "R-BTA-5696358", "name": "TREM,CD300 binds lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696348", "species_10076959" ], "products": [ "species_10076961" ], "modifiers": [], "additional_components": [ "species_428256", "species_1500646", "species_1602375", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "species_428256", "species_1500646", "species_1602375" ] }, "reaction_10042786": { "compartment": "compartment_876", "id": "reaction_10042786", "reactome": "R-BTA-199579", "name": "KIR2DL4 interacting with HLA-G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042782", "species_10042780" ], "products": [ "species_10042784" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813" ] }, "reaction_10084658": { "compartment": "compartment_876", "id": "reaction_10084658", "reactome": "R-BTA-8862084", "name": "PILRA,PILRB bind CD99", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084654", "species_10084650" ], "products": [ "species_10084656" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087222", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1NN33", "ENSBTAT00000087222" ] }, "reaction_10074901": { "compartment": "compartment_876", "id": "reaction_10074901", "reactome": "R-BTA-5685604", "name": "SLAMF6 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074893" ], "products": [ "species_10074895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034482", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10043241": { "compartment": "compartment_70101", "id": "reaction_10043241", "reactome": "R-BTA-202354", "name": "Translocation of PLC-gamma1 to PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043234", "species_179856" ], "products": [ "species_10043239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "species_6810412", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043262": { "compartment": "compartment_70101", "id": "reaction_10043262", "reactome": "R-BTA-202407", "name": "PLC-gamma1 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10043259", "catalyst" ] ], "additional_components": [ "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043193": { "compartment": "compartment_70101", "id": "reaction_10043193", "reactome": "R-BTA-202203", "name": "Recruitment of PI3K to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043189", "species_10035523" ], "products": [ "species_10043191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074583", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043225": { "compartment": "compartment_70101", "id": "reaction_10043225", "reactome": "R-BTA-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043006", "species_112275" ], "products": [ "species_10043223" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043219": { "compartment": "compartment_70101", "id": "reaction_10043219", "reactome": "R-BTA-202237", "name": "Hydrolysis of PIP3 to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10043216", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077857" ] }, "reaction_10043252": { "compartment": "compartment_70101", "id": "reaction_10043252", "reactome": "R-BTA-202394", "name": "Translocation of CARMA1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043248", "species_10043180" ], "products": [ "species_10043250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043304": { "compartment": "compartment_70101", "id": "reaction_10043304", "reactome": "R-BTA-202489", "name": "Oligomerization of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043279", "species_10043295" ], "products": [ "species_10043281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043274": { "compartment": "compartment_876", "id": "reaction_10043274", "reactome": "R-BTA-202443", "name": "Oligomerization of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043267", "species_10043265" ], "products": [ "species_10043272" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043244": { "compartment": "compartment_70101", "id": "reaction_10043244", "reactome": "R-BTA-202365", "name": "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10043191", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043212": { "compartment": "compartment_876", "id": "reaction_10043212", "reactome": "R-BTA-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10043209" ], "modifiers": [ [ "species_10043180", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043182": { "compartment": "compartment_70101", "id": "reaction_10043182", "reactome": "R-BTA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202277", "species_10043178" ], "products": [ "species_10043180" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043298": { "compartment": "compartment_70101", "id": "reaction_10043298", "reactome": "R-BTA-202459", "name": "Phosphorylation of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043293" ], "products": [ "species_29370", "species_10043295" ], "modifiers": [ [ "species_10041331", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000020312" ] }, "reaction_10043300": { "compartment": "compartment_70101", "id": "reaction_10043300", "reactome": "R-BTA-202466", "name": "Interaction of Bcl10 to CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043291", "species_10043272" ], "products": [ "species_10043293" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043270": { "compartment": "compartment_70101", "id": "reaction_10043270", "reactome": "R-BTA-202437", "name": "Phosphorylation of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043250", "species_113592" ], "products": [ "species_29370", "species_10043267" ], "modifiers": [ [ "species_10043209", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043302": { "compartment": "compartment_70101", "id": "reaction_10043302", "reactome": "R-BTA-202472", "name": "Translocation of TRAF6 to CBM complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043287", "species_10039473" ], "products": [ "species_10043289" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10055448": { "compartment": "compartment_70101", "id": "reaction_10055448", "reactome": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055446" ], "products": [ "species_983123", "species_10055330" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055451": { "compartment": "compartment_70101", "id": "reaction_10055451", "reactome": "R-BTA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055428", "species_113592", "species_10055422" ], "products": [ "species_111294", "species_10055446", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055428", "catalyst" ] ], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10055453": { "compartment": "compartment_70101", "id": "reaction_10055453", "reactome": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055330", "species_10055422", "species_983035" ], "products": [ "species_10055424" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055491": { "compartment": "compartment_70101", "id": "reaction_10055491", "reactome": "R-BTA-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10055488", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "E1BP91", "ENSBTAT00000015199", "E1BL29", "ENSBTAT00000028490" ] }, "reaction_10055431": { "compartment": "compartment_70101", "id": "reaction_10055431", "reactome": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055424", "species_113592" ], "products": [ "species_111294", "species_10055428", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055330", "catalyst" ] ], "additional_components": [ "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10061657": { "compartment": "compartment_876", "id": "reaction_10061657", "reactome": "R-BTA-1973968", "name": "Beta-defensins 4A and 103 bind CCR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061653", "species_10045084" ], "products": [ "species_10061655" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "ENSBTAT00000018066", "A0A3S5ZP45", "ENSBTAT00000018066", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783" ] }, "reaction_10058456": { "compartment": "compartment_984", "id": "reaction_10058456", "reactome": "R-BTA-1467269", "name": "Beta-defensins bind microbial membranes causing disruption", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058452", "species_1462049" ], "products": [ "species_10058454" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "species_1462049", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10058492": { "compartment": "compartment_984", "id": "reaction_10058492", "reactome": "R-BTA-1471338", "name": "Beta-defensins 1, 4A and 103 bind CCR6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045160", "species_10058488" ], "products": [ "species_10058490" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "F1MT56", "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10058486": { "compartment": "compartment_17963", "id": "reaction_10058486", "reactome": "R-BTA-1471322", "name": "Beta-defensins are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058484" ], "products": [ "species_10058452" ], "modifiers": [], "additional_components": [ "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10063801": { "compartment": "compartment_161320", "id": "reaction_10063801", "reactome": "R-BTA-2090037", "name": "IDUA hydrolyses Heparan sulfate chain(6)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090055" ], "products": [ "species_2090070", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10063803": { "compartment": "compartment_161320", "id": "reaction_10063803", "reactome": "R-BTA-2090038", "name": "NAGLU hydrolyses heparan chain(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090053" ], "products": [ "species_1678743", "species_2065212" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10060634": { "compartment": "compartment_17938", "id": "reaction_10060634", "reactome": "R-BTA-1678660", "name": "HGSNAT oligomer acetylates Heparan sulfate chain(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090040", "species_76183" ], "products": [ "species_2090069", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060685": { "compartment": "compartment_161320", "id": "reaction_10060685", "reactome": "R-BTA-1678742", "name": "NAGLU hydrolyses Heparan sulfate chain(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090069" ], "products": [ "species_2090080", "species_1678743" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10063805": { "compartment": "compartment_17938", "id": "reaction_10063805", "reactome": "R-BTA-2090085", "name": "HGSNAT oligomer acetylates Heparan chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_2090045" ], "products": [ "species_2090053", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060671": { "compartment": "compartment_876", "id": "reaction_10060671", "reactome": "R-BTA-1678694", "name": "Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10060650" ], "products": [ "species_2090023", "species_10060664" ], "modifiers": [ [ "species_10060668", "catalyst" ] ], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "ENSBTAT00000085333" ] }, "reaction_10063022": { "compartment": "compartment_876", "id": "reaction_10063022", "reactome": "R-BTA-2024084", "name": "HS-GAGs translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060650" ], "products": [ "species_10060394" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1MZX8", "ENSBTAT00000011475", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "Q3ZBZ6", "ENSBTAT00000027192" ] }, "reaction_10060625": { "compartment": "compartment_161320", "id": "reaction_10060625", "reactome": "R-BTA-1678650", "name": "IDS hydrolyses Heparan sulfate chain(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090080", "species_1605715" ], "products": [ "species_2090055", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10060741": { "compartment": "compartment_161320", "id": "reaction_10060741", "reactome": "R-BTA-1678854", "name": "GUSB tetramer hydrolyses CS/HS precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065212" ], "products": [ "species_1678868", "species_2090075" ], "modifiers": [ [ "species_10060738", "catalyst" ], [ "species_427963", "inhibitor" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10060678": { "compartment": "compartment_161320", "id": "reaction_10060678", "reactome": "R-BTA-1678716", "name": "IDUA hydrolyses Heparan sulfate chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090033", "species_1605715" ], "products": [ "species_2090072", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10072894": { "compartment": "compartment_17963", "id": "reaction_10072894", "reactome": "R-BTA-5653878", "name": "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_964746" ], "products": [ "species_5653871", "species_205687" ], "modifiers": [ [ "species_10072891", "catalyst" ] ], "additional_components": [ "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10072898": { "compartment": "compartment_17963", "id": "reaction_10072898", "reactome": "R-BTA-5653886", "name": "B4GALT1 binds LALBA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072896", "species_10054442" ], "products": [ "species_10072891" ], "modifiers": [ [ "species_735682", "catalyst" ], [ "species_5653875", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066421", "ENSBTAT00000020286", "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10033611": { "compartment": "compartment_70101", "id": "reaction_10033611", "reactome": "R-BTA-70449", "name": "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_29578", "species_29360" ], "products": [ "species_70106", "species_29800", "species_73473" ], "modifiers": [ [ "species_10033608", "catalyst" ] ], "additional_components": [ "P10096", "ENSBTAT00000037753", "Q2KJE5", "ENSBTAT00000021166" ] }, "reaction_10080765": { "compartment": "compartment_70101", "id": "reaction_10080765", "reactome": "R-BTA-6799604", "name": "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449701" ], "products": [ "species_29512", "species_31633" ], "modifiers": [ [ "species_10080762", "catalyst" ] ], "additional_components": [ "A0A452DIC9", "ENSBTAT00000000357" ] }, "reaction_10033629": { "compartment": "compartment_70101", "id": "reaction_10033629", "reactome": "R-BTA-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_30014", "species_29370" ], "modifiers": [ [ "species_10033626", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_76190", "inhibitor" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "A1A4J1", "ENSBTAT00000056305" ] }, "reaction_10034157": { "compartment": "compartment_70101", "id": "reaction_10034157", "reactome": "R-BTA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10034154", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "species_29926", "species_74126", "Q1JPG7", "ENSBTAT00000086042", "A5D984", "ENSBTAT00000047412" ] }, "reaction_10034140": { "compartment": "compartment_70101", "id": "reaction_10034140", "reactome": "R-BTA-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10034049", "catalyst" ] ], "additional_components": [ "Q3SZ62", "ENSBTAT00000032937" ] }, "reaction_10076815": { "compartment": "compartment_12045", "id": "reaction_10076815", "reactome": "R-BTA-5696021", "name": "ADPGK:Mg2+ phosphorylates Glc to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_70113" ], "products": [ "species_30537", "species_76577" ], "modifiers": [ [ "species_10076812", "catalyst" ] ], "additional_components": [ "species_29926", "A2VE47", "ENSBTAT00000002065" ] }, "reaction_10088737": { "compartment": "compartment_70101", "id": "reaction_10088737", "reactome": "R-BTA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10033547", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926" ] }, "reaction_10033620": { "compartment": "compartment_70101", "id": "reaction_10033620", "reactome": "R-BTA-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10033617", "catalyst" ] ], "additional_components": [ "A0A452DIX3", "ENSBTAT00000026358" ] }, "reaction_10034071": { "compartment": "compartment_70101", "id": "reaction_10034071", "reactome": "R-BTA-71496", "name": "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014" ], "products": [ "species_29578", "species_75970" ], "modifiers": [ [ "species_10034066", "catalyst" ] ], "additional_components": [ "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416" ] }, "reaction_10078710": { "compartment": "compartment_70101", "id": "reaction_10078710", "reactome": "R-BTA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10078707", "catalyst" ] ], "additional_components": [ "F1MX69", "ENSBTAT00000070308" ] }, "reaction_10045050": { "compartment": "compartment_70101", "id": "reaction_10045050", "reactome": "R-BTA-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10033757": { "compartment": "compartment_5460", "id": "reaction_10033757", "reactome": "R-BTA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10041885": { "compartment": "compartment_70101", "id": "reaction_10041885", "reactome": "R-BTA-198513", "name": "Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10041882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077820" ] }, "reaction_10045692": { "compartment": "compartment_70101", "id": "reaction_10045692", "reactome": "R-BTA-376851", "name": "Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_198498" ], "products": [ "species_29406", "species_113544" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10034238": { "compartment": "compartment_17957", "id": "reaction_10034238", "reactome": "R-BTA-71825", "name": "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10034235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013436" ] }, "reaction_10045043": { "compartment": "compartment_5460", "id": "reaction_10045043", "reactome": "R-BTA-372819", "name": "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113573", "species_113587" ], "products": [ "species_372364", "species_113525", "species_29376" ], "modifiers": [ [ "species_10045040", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015834" ] }, "reaction_10041878": { "compartment": "compartment_70101", "id": "reaction_10041878", "reactome": "R-BTA-198440", "name": "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_113544" ], "products": [ "species_113594", "species_198498" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10033718": { "compartment": "compartment_70101", "id": "reaction_10033718", "reactome": "R-BTA-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29448" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10067254": { "compartment": "compartment_17957", "id": "reaction_10067254", "reactome": "R-BTA-3266566", "name": "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005552" ] }, "reaction_10067240": { "compartment": "compartment_70101", "id": "reaction_10067240", "reactome": "R-BTA-3257122", "name": "SLC37A1, SLC37A2 exchange G6P for Pi across the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10067237", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069229" ] }, "reaction_10067247": { "compartment": "compartment_17957", "id": "reaction_10067247", "reactome": "R-BTA-3262512", "name": "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021621" ] }, "reaction_10045029": { "compartment": "compartment_70101", "id": "reaction_10045029", "reactome": "R-BTA-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10045026", "catalyst" ] ], "additional_components": [ "A0A3Q1M9V5", "ENSBTAT00000083179", "A0A3Q1LHX4", "ENSBTAT00000073854" ] }, "reaction_10033638": { "compartment": "compartment_70101", "id": "reaction_10033638", "reactome": "R-BTA-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10033635", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "Q3SZB7", "ENSBTAT00000012835" ] }, "reaction_10033561": { "compartment": "compartment_70101", "id": "reaction_10033561", "reactome": "R-BTA-70333", "name": "KHK dimer phosphorylates Fru to Fru 1-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29532", "species_113592" ], "products": [ "species_29370", "species_31221" ], "modifiers": [ [ "species_10033558", "catalyst" ], [ "species_29804", "catalyst" ], [ "species_29370", "inhibitor" ] ], "additional_components": [ "Q0II75", "ENSBTAT00000015052" ] }, "reaction_10083115": { "compartment": "compartment_70101", "id": "reaction_10083115", "reactome": "R-BTA-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30393", "species_29360" ], "products": [ "species_6799497", "species_70106", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10033570": { "compartment": "compartment_70101", "id": "reaction_10033570", "reactome": "R-BTA-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_113592" ], "products": [ "species_29578", "species_29370" ], "modifiers": [ [ "species_10033567", "catalyst" ] ], "additional_components": [ "A0A3Q1MGZ4", "ENSBTAT00000085239", "species_29926" ] }, "reaction_10072825": { "compartment": "compartment_70101", "id": "reaction_10072825", "reactome": "R-BTA-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10063530": { "compartment": "compartment_20699", "id": "reaction_10063530", "reactome": "R-BTA-2046285", "name": "The keratan chain can be capped by N-acetylneuraminic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10063528" ], "products": [ "species_10063493", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10063485": { "compartment": "compartment_17963", "id": "reaction_10063485", "reactome": "R-BTA-2046180", "name": "KSPG is secreted from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063470" ], "products": [ "species_10063483" ], "modifiers": [], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854" ] }, "reaction_10063532": { "compartment": "compartment_20699", "id": "reaction_10063532", "reactome": "R-BTA-2046298", "name": "B4GALTs transfer Gal to a branch of keratan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063518" ], "products": [ "species_205687", "species_10063528" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063249": { "compartment": "compartment_20699", "id": "reaction_10063249", "reactome": "R-BTA-2025724", "name": "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10063230" ], "products": [ "species_205687", "species_10063240" ], "modifiers": [ [ "species_10063246", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A7YY64", "ENSBTAT00000024024", "Q5EA01", "ENSBTAT00000030023", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494" ] }, "reaction_10063232": { "compartment": "compartment_20699", "id": "reaction_10063232", "reactome": "R-BTA-2025723", "name": "B4GALTs transfer Gal to the N-glycan precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063222", "species_735682" ], "products": [ "species_10063230", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063520": { "compartment": "compartment_20699", "id": "reaction_10063520", "reactome": "R-BTA-2046265", "name": "B4GALTs transfer Gal to the keratan chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063240" ], "products": [ "species_10063518", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063477": { "compartment": "compartment_20699", "id": "reaction_10063477", "reactome": "R-BTA-2046175", "name": "Further sulfation on galactose residues produces KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063464" ], "products": [ "species_742343", "species_10063470" ], "modifiers": [ [ "species_10063474", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "ENSBTAT00000004844" ] }, "reaction_10063508": { "compartment": "compartment_20699", "id": "reaction_10063508", "reactome": "R-BTA-2046222", "name": "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063493", "species_741440" ], "products": [ "species_742343", "species_10063464" ], "modifiers": [ [ "species_10063505", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "E1BMN6", "ENSBTAT00000015389", "E1BK55", "ENSBTAT00000056191" ] }, "reaction_10060825": { "compartment": "compartment_161320", "id": "reaction_10060825", "reactome": "R-BTA-1793182", "name": "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065213" ], "products": [ "species_2065269", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10091289": { "compartment": "compartment_161320", "id": "reaction_10091289", "reactome": "R-BTA-9638075", "name": "HEXB cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060827": { "compartment": "compartment_161320", "id": "reaction_10060827", "reactome": "R-BTA-1793186", "name": "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105025" ], "products": [ "species_2104993", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10060842": { "compartment": "compartment_161320", "id": "reaction_10060842", "reactome": "R-BTA-1793209", "name": "HYAL1 hydrolyses Chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065257" ], "products": [ "species_2065212" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "CHEBI:63515", "species_2065239", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10060829": { "compartment": "compartment_161320", "id": "reaction_10060829", "reactome": "R-BTA-1793207", "name": "ARSB hydrolyses C4S/C6S chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2065251", "species_1605715" ], "products": [ "species_2065239", "species_1606845" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10062655": { "compartment": "compartment_984", "id": "reaction_10062655", "reactome": "R-BTA-2022056", "name": "DSPG and CSPG translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062551", "species_10062589" ], "products": [ "species_10062627", "species_10062653" ], "modifiers": [], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562" ] }, "reaction_10060031": { "compartment": "compartment_161320", "id": "reaction_10060031", "reactome": "R-BTA-1606789", "name": "ARSB hydrolyses DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065231" ], "products": [ "species_1606845", "species_2065213" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10063807": { "compartment": "compartment_161320", "id": "reaction_10063807", "reactome": "R-BTA-2105001", "name": "HEXA cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10061642": { "compartment": "compartment_20699", "id": "reaction_10061642", "reactome": "R-BTA-1971487", "name": "CHPF,CHSY3 transfer GalNAc to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10061629" ], "products": [ "species_10061574", "species_205687" ], "modifiers": [ [ "species_10061639", "catalyst" ] ], "additional_components": [ "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10061612": { "compartment": "compartment_20699", "id": "reaction_10061612", "reactome": "R-BTA-1971483", "name": "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_10061591", "species_742343" ], "modifiers": [ [ "species_10061609", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N663", "ENSBTAT00000014069", "A0A3Q1M362", "ENSBTAT00000073469", "A6QLZ9", "ENSBTAT00000011567", "A0A3Q1MTD8", "ENSBTAT00000068924" ] }, "reaction_10062463": { "compartment": "compartment_20699", "id": "reaction_10062463", "reactome": "R-BTA-2018682", "name": "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_742343", "species_10062450" ], "modifiers": [ [ "species_10062460", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "G3X6P1", "ENSBTAT00000010069", "E1BPN4", "ENSBTAT00000074793" ] }, "reaction_10061651": { "compartment": "compartment_20699", "id": "reaction_10061651", "reactome": "R-BTA-1971491", "name": "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061557" ], "products": [ "species_10061629", "species_205687" ], "modifiers": [ [ "species_10061648", "catalyst" ] ], "additional_components": [ "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "E1B9D0", "ENSBTAT00000019108", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10063014": { "compartment": "compartment_17963", "id": "reaction_10063014", "reactome": "R-BTA-2022911", "name": "CSPG is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063012" ], "products": [ "species_10062589" ], "modifiers": [], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562" ] }, "reaction_10061402": { "compartment": "compartment_20699", "id": "reaction_10061402", "reactome": "R-BTA-1889981", "name": "B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061238", "species_735682" ], "products": [ "species_10061388", "species_205687" ], "modifiers": [ [ "species_10061399", "catalyst" ] ], "additional_components": [ "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000035663" ] }, "reaction_10061251": { "compartment": "compartment_20699", "id": "reaction_10061251", "reactome": "R-BTA-1878002", "name": "XYLTs transfer Xyl to core protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061200", "species_742361" ], "products": [ "species_10061238", "species_205687" ], "modifiers": [ [ "species_10061248", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MY84", "ENSBTAT00000016206", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q0VCM1", "ENSBTAT00000002979", "Q3ZBZ6", "ENSBTAT00000027192", "P21793", "ENSBTAT00000004562", "F1MZX8", "ENSBTAT00000011475", "F1N2Y8", "ENSBTAT00000002312", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1N211", "ENSBTAT00000007264", "A0A3Q1LSF3", "ENSBTAT00000070229" ] }, "reaction_10061395": { "compartment": "compartment_20699", "id": "reaction_10061395", "reactome": "R-BTA-1889978", "name": "B3GALT6 transfers Gal to the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10061388" ], "products": [ "species_205687", "species_10061289" ], "modifiers": [ [ "species_10061392", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "ENSBTAT00000057493" ] }, "reaction_10061350": { "compartment": "compartment_20699", "id": "reaction_10061350", "reactome": "R-BTA-1889955", "name": "B3GAT dimers transfer GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061347", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1M0B6", "ENSBTAT00000083529", "species_113527", "A0A3Q1LG25", "ENSBTAT00000080834", "F1MQ60", "ENSBTAT00000070592" ] }, "reaction_10091286": { "compartment": "compartment_20699", "id": "reaction_10091286", "reactome": "R-BTA-9638064", "name": "B3GAT3 dimer transfers GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061345", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1LG25", "ENSBTAT00000080834", "species_113527" ] }, "reaction_10062697": { "compartment": "compartment_20699", "id": "reaction_10062697", "reactome": "R-BTA-2022063", "name": "CHST14 transfers SO4(2-) to GalNAc in dermatan or DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062676", "species_741440" ], "products": [ "species_742343", "species_10062690" ], "modifiers": [ [ "species_10062694", "catalyst" ] ], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000005795" ] }, "reaction_10062701": { "compartment": "compartment_17963", "id": "reaction_10062701", "reactome": "R-BTA-2022065", "name": "DSPGs are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062699" ], "products": [ "species_10062551" ], "modifiers": [], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312" ] }, "reaction_10062508": { "compartment": "compartment_20699", "id": "reaction_10062508", "reactome": "R-BTA-2022052", "name": "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062465" ], "products": [ "species_10062501" ], "modifiers": [ [ "species_10062505", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000056960" ] }, "reaction_10062674": { "compartment": "compartment_20699", "id": "reaction_10062674", "reactome": "R-BTA-2022061", "name": "Dermatan sulfate can be further sulfated on position 2 of iduronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10062482" ], "products": [ "species_742343", "species_10062667" ], "modifiers": [ [ "species_10062671", "catalyst" ] ], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000068674" ] }, "reaction_10039887": { "compartment": "compartment_70101", "id": "reaction_10039887", "reactome": "R-BTA-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174370" ], "products": [ "species_29370", "species_158471" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10039890": { "compartment": "compartment_70101", "id": "reaction_10039890", "reactome": "R-BTA-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174375" ], "products": [ "species_111294", "species_174370" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10051570": { "compartment": "compartment_20699", "id": "reaction_10051570", "reactome": "R-BTA-741449", "name": "SLC35B2,3 transport cytosolic PAPS to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471" ], "products": [ "species_741440" ], "modifiers": [ [ "species_10051567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010620" ] }, "reaction_10048727": { "compartment": "compartment_876", "id": "reaction_10048727", "reactome": "R-BTA-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_427648" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10048724", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019462" ] }, "reaction_10064353": { "compartment": "compartment_876", "id": "reaction_10064353", "reactome": "R-BTA-2160851", "name": "HAS1,2,3 mediate the polymerisation of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142867" ], "products": [ "species_2142896" ], "modifiers": [ [ "species_10064350", "catalyst" ] ], "additional_components": [ "species_2162224", "ENSBTAT00000071722" ] }, "reaction_10064393": { "compartment": "compartment_876", "id": "reaction_10064393", "reactome": "R-BTA-2160915", "name": "Receptor-mediated uptake of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064359", "species_10064373", "species_2160848" ], "products": [ "species_10064375" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070191", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "species_2162224", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10091291": { "compartment": "compartment_161320", "id": "reaction_10091291", "reactome": "R-BTA-9638076", "name": "HEXB cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064593": { "compartment": "compartment_161320", "id": "reaction_10064593", "reactome": "R-BTA-2162225", "name": "HEXA cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064355": { "compartment": "compartment_161320", "id": "reaction_10064355", "reactome": "R-BTA-2160874", "name": "HYAL1 hydrolyses (HA)50", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160864" ], "products": [ "species_2160866" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "species_2162224", "species_2162224", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10064595": { "compartment": "compartment_161320", "id": "reaction_10064595", "reactome": "R-BTA-2162226", "name": "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2162224" ], "products": [ "species_1678743", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064597": { "compartment": "compartment_161320", "id": "reaction_10064597", "reactome": "R-BTA-2162227", "name": "GUSB tetramer hydrolyses (HA)2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160866" ], "products": [ "species_2162223", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "species_2162224", "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064391": { "compartment": "compartment_876", "id": "reaction_10064391", "reactome": "R-BTA-2160892", "name": "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064388" ], "products": [ "species_2160894", "species_10064388" ], "modifiers": [ [ "species_10064388", "catalyst" ] ], "additional_components": [ "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "species_2162224", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10033579": { "compartment": "compartment_70101", "id": "reaction_10033579", "reactome": "R-BTA-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10033576", "catalyst" ] ], "additional_components": [ "species_29360", "A0A452DIP2", "ENSBTAT00000006586" ] }, "reaction_10033594": { "compartment": "compartment_70101", "id": "reaction_10033594", "reactome": "R-BTA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10033549", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10090620": { "compartment": "compartment_70101", "id": "reaction_10090620", "reactome": "R-BTA-9033959", "name": "ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_9033793" ], "products": [ "species_205687", "species_9033802" ], "modifiers": [ [ "species_10090617", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090703": { "compartment": "compartment_17963", "id": "reaction_10090703", "reactome": "R-BTA-9036987", "name": "FUT2 transfers Fuc to Type 1 chains to form H antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9037036" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090638": { "compartment": "compartment_984", "id": "reaction_10090638", "reactome": "R-BTA-9034042", "name": "sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034046" ], "products": [ "species_417888", "species_9037066" ], "modifiers": [ [ "species_10090635", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090611": { "compartment": "compartment_17963", "id": "reaction_10090611", "reactome": "R-BTA-9033949", "name": "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_205689", "species_9033793" ], "modifiers": [ [ "species_10090608", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023560" ] }, "reaction_10090645": { "compartment": "compartment_984", "id": "reaction_10090645", "reactome": "R-BTA-9034053", "name": "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034065" ], "products": [ "species_417888", "species_9037067" ], "modifiers": [ [ "species_10090642", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090631": { "compartment": "compartment_70101", "id": "reaction_10090631", "reactome": "R-BTA-9033961", "name": "ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_9033793" ], "products": [ "species_9033798", "species_205687" ], "modifiers": [ [ "species_10090628", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090856": { "compartment": "compartment_17963", "id": "reaction_10090856", "reactome": "R-BTA-9605644", "name": "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605649", "species_205683" ], "products": [ "species_205689", "species_9605651" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090797": { "compartment": "compartment_17963", "id": "reaction_10090797", "reactome": "R-BTA-9603984", "name": "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_9605593", "species_205689" ], "modifiers": [ [ "species_10090794", "catalyst" ] ], "additional_components": [ "F1MDG4", "ENSBTAT00000056091", "F1MBS8", "ENSBTAT00000000529", "F1N751", "ENSBTAT00000010501" ] }, "reaction_10090799": { "compartment": "compartment_17963", "id": "reaction_10090799", "reactome": "R-BTA-9603986", "name": "FUT3 transfers Fuc to Type 1 chains to form LeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9605607" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090819": { "compartment": "compartment_17963", "id": "reaction_10090819", "reactome": "R-BTA-9603989", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9604808", "species_735682" ], "products": [ "species_205687", "species_9036984" ], "modifiers": [ [ "species_10090816", "catalyst" ] ], "additional_components": [ "Q2HJA3", "ENSBTAT00000036248", "F1MSJ4", "ENSBTAT00000031889", "Q3T0R9", "ENSBTAT00000022206" ] }, "reaction_10090851": { "compartment": "compartment_17963", "id": "reaction_10090851", "reactome": "R-BTA-9605600", "name": "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9033790" ], "products": [ "species_727810", "species_9605685" ], "modifiers": [ [ "species_10090848", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324" ] }, "reaction_10090867": { "compartment": "compartment_17963", "id": "reaction_10090867", "reactome": "R-BTA-9605682", "name": "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605685", "species_205683" ], "products": [ "species_9605661", "species_205689" ], "modifiers": [ [ "species_10090864", "catalyst" ] ], "additional_components": [ "G3MZR2", "ENSBTAT00000066072", "F1MBS8", "ENSBTAT00000000529" ] }, "reaction_10090802": { "compartment": "compartment_17963", "id": "reaction_10090802", "reactome": "R-BTA-9603987", "name": "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9036984" ], "products": [ "species_727810", "species_9605595" ], "modifiers": [ [ "species_10054713", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078218" ] }, "reaction_10090772": { "compartment": "compartment_17963", "id": "reaction_10090772", "reactome": "R-BTA-9603982", "name": "FUT2 transfers Fuc to LeA to form LeB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605607", "species_205683" ], "products": [ "species_205689", "species_9605394" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090774": { "compartment": "compartment_17963", "id": "reaction_10090774", "reactome": "R-BTA-9603983", "name": "FUT2 transfers Fuc to LeX to form LeY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605593", "species_205683" ], "products": [ "species_205689", "species_9605586" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090854": { "compartment": "compartment_17963", "id": "reaction_10090854", "reactome": "R-BTA-9605609", "name": "FUT3 transfers Fuc to Type 1 MSGG to form sLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605595", "species_205683" ], "products": [ "species_9605615", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090822": { "compartment": "compartment_17963", "id": "reaction_10090822", "reactome": "R-BTA-9603991", "name": "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9605595" ], "products": [ "species_727810", "species_9605649" ], "modifiers": [ [ "species_10069341", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061027" ] }, "reaction_10034041": { "compartment": "compartment_70101", "id": "reaction_10034041", "reactome": "R-BTA-71324", "name": "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_73578" ], "products": [ "species_29882", "species_29578" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10033592": { "compartment": "compartment_70101", "id": "reaction_10033592", "reactome": "R-BTA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10033589", "catalyst" ] ], "additional_components": [ "A0A3Q1MM55", "ENSBTAT00000067626", "species_113563" ] }, "reaction_10034043": { "compartment": "compartment_70101", "id": "reaction_10034043", "reactome": "R-BTA-71335", "name": "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_29878" ], "products": [ "species_29578", "species_29512" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10034013": { "compartment": "compartment_70101", "id": "reaction_10034013", "reactome": "R-BTA-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29996", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_29732" ], "modifiers": [ [ "species_10034010", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM3", "ENSBTAT00000017988" ] }, "reaction_10042801": { "compartment": "compartment_70101", "id": "reaction_10042801", "reactome": "R-BTA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10034032": { "compartment": "compartment_70101", "id": "reaction_10034032", "reactome": "R-BTA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10088744": { "compartment": "compartment_70101", "id": "reaction_10088744", "reactome": "R-BTA-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_73578", "species_29370" ], "modifiers": [ [ "species_10088741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044396" ] }, "reaction_10089230": { "compartment": "compartment_70101", "id": "reaction_10089230", "reactome": "R-BTA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10077793": { "compartment": "compartment_70101", "id": "reaction_10077793", "reactome": "R-BTA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10088898": { "compartment": "compartment_70101", "id": "reaction_10088898", "reactome": "R-BTA-8959719", "name": "SHPK phosphorylates Sedo to Sedo7P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8959707" ], "products": [ "species_70106", "species_29370", "species_29882" ], "modifiers": [ [ "species_10088895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001095" ] }, "reaction_10073438": { "compartment": "compartment_70101", "id": "reaction_10073438", "reactome": "R-BTA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10073431": { "compartment": "compartment_70101", "id": "reaction_10073431", "reactome": "R-BTA-5661240", "name": "DCXR tetramer reduces L-xylulose to xylitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_5660036" ], "products": [ "species_5660033", "species_29366" ], "modifiers": [ [ "species_10073428", "catalyst" ] ], "additional_components": [ "A5PJR3", "ENSBTAT00000085766", "Q1JP75", "ENSBTAT00000085766" ] }, "reaction_10080747": { "compartment": "compartment_70101", "id": "reaction_10080747", "reactome": "R-BTA-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6799540" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10080744", "catalyst" ] ], "additional_components": [ "species_29426", "F1MWT0", "ENSBTAT00000009690" ] }, "reaction_10084129": { "compartment": "compartment_161320", "id": "reaction_10084129", "reactome": "R-BTA-8853686", "name": "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_8853396" ], "products": [ "species_6799577", "species_6799594" ], "modifiers": [ [ "species_10084126", "catalyst" ] ], "additional_components": [ "Q29451", "ENSBTAT00000070599", "species_29426" ] }, "reaction_10080756": { "compartment": "compartment_161320", "id": "reaction_10080756", "reactome": "R-BTA-6799581", "name": "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799577", "species_1605715" ], "products": [ "species_6799594", "species_8853719" ], "modifiers": [ [ "species_10080753", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ5", "ENSBTAT00000081381", "species_29426" ] }, "reaction_10067610": { "compartment": "compartment_70101", "id": "reaction_10067610", "reactome": "R-BTA-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067605", "species_29410" ], "products": [ "species_10067607", "species_110096" ], "modifiers": [ [ "species_10067605", "catalyst" ] ], "additional_components": [ "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10067644": { "compartment": "compartment_70101", "id": "reaction_10067644", "reactome": "R-BTA-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067619", "species_29410" ], "products": [ "species_110096", "species_10067641" ], "modifiers": [ [ "species_10067619", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10068748": { "compartment": "compartment_70101", "id": "reaction_10068748", "reactome": "R-BTA-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068745" ], "products": [ "species_10068740", "species_29372" ], "modifiers": [ [ "species_10068745", "catalyst" ] ], "additional_components": [ "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067648": { "compartment": "compartment_70101", "id": "reaction_10067648", "reactome": "R-BTA-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067641" ], "products": [ "species_10067646" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "ENSBTAT00000083071" ] }, "reaction_10068752": { "compartment": "compartment_70101", "id": "reaction_10068752", "reactome": "R-BTA-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067627", "species_10068729" ], "products": [ "species_10068750" ], "modifiers": [], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10068755": { "compartment": "compartment_70101", "id": "reaction_10068755", "reactome": "R-BTA-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068750", "species_29410" ], "products": [ "species_109402", "species_10068734" ], "modifiers": [ [ "species_10068750", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067634": { "compartment": "compartment_70101", "id": "reaction_10067634", "reactome": "R-BTA-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067607" ], "products": [ "species_10067627" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000083071" ] }, "reaction_10067639": { "compartment": "compartment_70101", "id": "reaction_10067639", "reactome": "R-BTA-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067636", "species_29410" ], "products": [ "species_10067605", "species_110096" ], "modifiers": [ [ "species_10067636", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067622": { "compartment": "compartment_70101", "id": "reaction_10067622", "reactome": "R-BTA-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067617", "species_29410" ], "products": [ "species_10067619", "species_110096" ], "modifiers": [ [ "species_10067617", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926" ] }, "reaction_10090696": { "compartment": "compartment_161320", "id": "reaction_10090696", "reactome": "R-BTA-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10090685" ], "products": [ "species_1605745", "species_10090689" ], "modifiers": [ [ "species_10090691", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "ENSBTAT00000021325" ] }, "reaction_10034138": { "compartment": "compartment_70101", "id": "reaction_10034138", "reactome": "R-BTA-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034111" ], "products": [ "species_10034135", "species_70113" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10050637": { "compartment": "compartment_70101", "id": "reaction_10050637", "reactome": "R-BTA-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050635" ], "products": [ "species_10034078", "species_76577" ], "modifiers": [], "additional_components": [ "species_76577", "F1MJ28", "ENSBTAT00000001373", "F1MJ28", "ENSBTAT00000001373" ] }, "reaction_10034118": { "compartment": "compartment_70101", "id": "reaction_10034118", "reactome": "R-BTA-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034099" ], "products": [ "species_10034111" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10033737": { "compartment": "compartment_70101", "id": "reaction_10033737", "reactome": "R-BTA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10033734", "catalyst" ] ], "additional_components": [ "Q1LZA3", "ENSBTAT00000079655" ] }, "reaction_10078529": { "compartment": "compartment_70101", "id": "reaction_10078529", "reactome": "R-BTA-6797627", "name": "ASPG hydrolyses L-Asn to L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29642" ], "products": [ "species_29448", "species_29382" ], "modifiers": [ [ "species_10078526", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066927" ] }, "reaction_10033728": { "compartment": "compartment_5460", "id": "reaction_10033728", "reactome": "R-BTA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10076130": { "compartment": "compartment_70101", "id": "reaction_10076130", "reactome": "R-BTA-5691507", "name": "ASPA deacetylates NAA to acetate and L-aspartate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5691492" ], "products": [ "species_29416", "species_29448" ], "modifiers": [ [ "species_10076127", "catalyst" ] ], "additional_components": [ "F1MUZ8", "ENSBTAT00000069554", "species_29426" ] }, "reaction_10033716": { "compartment": "compartment_70101", "id": "reaction_10033716", "reactome": "R-BTA-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_76213" ], "products": [ "species_29406", "species_29448" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10076406": { "compartment": "compartment_876", "id": "reaction_10076406", "reactome": "R-BTA-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10076403", "catalyst" ] ], "additional_components": [ "F1MUP1", "ENSBTAT00000009723", "F1MGS8", "ENSBTAT00000000354" ] }, "reaction_10043917": { "compartment": "compartment_70101", "id": "reaction_10043917", "reactome": "R-BTA-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914", "species_76183" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10043914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019543" ] }, "reaction_10043948": { "compartment": "compartment_70101", "id": "reaction_10043948", "reactome": "R-BTA-209828", "name": "Tryptophan is hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29500", "species_29368" ], "products": [ "species_71112", "species_209911" ], "modifiers": [ [ "species_10043945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N5Q8", "ENSBTAT00000007030", "E1BGX6", "ENSBTAT00000027708" ] }, "reaction_10033681": { "compartment": "compartment_70101", "id": "reaction_10033681", "reactome": "R-BTA-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10033678", "catalyst" ] ], "additional_components": [ "A0A452DIW8", "ENSBTAT00000010309" ] }, "reaction_10091773": { "compartment": "compartment_876", "id": "reaction_10091773", "reactome": "R-BTA-9686930", "name": "RIPK3 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070522" ], "products": [ "species_10091771", "species_10091769" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000024511", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068030": { "compartment": "compartment_70101", "id": "reaction_10068030", "reactome": "R-BTA-3465429", "name": "FLIP(S) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035394", "species_10068026" ], "products": [ "species_10068028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074240": { "compartment": "compartment_70101", "id": "reaction_10074240", "reactome": "R-BTA-5675456", "name": "FLIP(L) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068034", "species_10068026" ], "products": [ "species_10068032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074254": { "compartment": "compartment_70101", "id": "reaction_10074254", "reactome": "R-BTA-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10071514" ], "products": [ "species_10074251" ], "modifiers": [ [ "species_10071514", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103" ] }, "reaction_10091806": { "compartment": "compartment_70101", "id": "reaction_10091806", "reactome": "R-BTA-9688831", "name": "STUB1 ubiquitinates RIPK3 at K55, K363", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091797", "species_10033408" ], "products": [ "species_10091803" ], "modifiers": [ [ "species_10091797", "catalyst" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091793": { "compartment": "compartment_70101", "id": "reaction_10091793", "reactome": "R-BTA-9687828", "name": "O-GlcNAcylation of RIPK3 (TLR4 signaling)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_10070522" ], "products": [ "species_10091786", "species_110096" ], "modifiers": [ [ "species_10091790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000045447" ] }, "reaction_10091808": { "compartment": "compartment_70101", "id": "reaction_10091808", "reactome": "R-BTA-9688832", "name": "MLKL binds PDCD6IP and SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072342", "species_10045220", "species_10067330" ], "products": [ "species_10072344" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023165", "ENSBTAT00000026526", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165" ] }, "reaction_10091779": { "compartment": "compartment_70101", "id": "reaction_10091779", "reactome": "R-BTA-9687625", "name": "ATP binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_10091777" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "species_113592", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10091810": { "compartment": "compartment_70101", "id": "reaction_10091810", "reactome": "R-BTA-9688838", "name": "RIPK3 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091795", "species_10070522" ], "products": [ "species_10091797" ], "modifiers": [], "additional_components": [ "E1B7G3", "ENSBTAT00000025473", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091783": { "compartment": "compartment_70101", "id": "reaction_10091783", "reactome": "R-BTA-9687638", "name": "MLKL binds IP4, IP5 and IP6 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994146", "species_10070686", "species_1629770", "species_994141" ], "products": [ "species_10091781" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_994141", "species_1629770", "species_994146" ] }, "reaction_10081481": { "compartment": "compartment_161320", "id": "reaction_10081481", "reactome": "R-BTA-6803753", "name": "NAAA hydrolyses NAEs to FAs and ethanolamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6803725" ], "products": [ "species_6803745", "species_6803778" ], "modifiers": [ [ "species_10081478", "catalyst" ] ], "additional_components": [ "CHEBI:71466", "species_5693754", "CHEBI:85299", "CHEBI:85263", "CHEBI:71464", "CHEBI:85262", "species_426576", "species_33549", "species_8934421", "CHEBI:28875", "CHEBI:16196", "species_140356", "F1MN16", "ENSBTAT00000025945" ] }, "reaction_10044540": { "compartment": "compartment_70101", "id": "reaction_10044540", "reactome": "R-BTA-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_264643", "species_76194" ], "modifiers": [ [ "species_10044537", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022369" ] }, "reaction_10049090": { "compartment": "compartment_876", "id": "reaction_10049090", "reactome": "R-BTA-429594", "name": "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_264638", "species_74113" ], "products": [ "species_264618", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049087", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005693" ] }, "reaction_10071437": { "compartment": "compartment_70101", "id": "reaction_10071437", "reactome": "R-BTA-5336443", "name": "LIN7, CASK and APBA1 bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071423", "species_10071419", "species_10071433" ], "products": [ "species_10071435" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071329", "ENSBTAT00000079326", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "A0A3Q1MLH9", "ENSBTAT00000079326", "A0A3Q1LPV4", "ENSBTAT00000071329" ] }, "reaction_10049583": { "compartment": "compartment_70101", "id": "reaction_10049583", "reactome": "R-BTA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049580", "catalyst" ] ], "additional_components": [ "A5PJX7", "ENSBTAT00000019308", "E1BPI1", "ENSBTAT00000038826" ] }, "reaction_10052018": { "compartment": "compartment_70101", "id": "reaction_10052018", "reactome": "R-BTA-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10052015", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063578" ] }, "reaction_10052013": { "compartment": "compartment_917757", "id": "reaction_10052013", "reactome": "R-BTA-888577", "name": "Synthesis of GABA by GAD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10052010", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547", "F1N6X2", "ENSBTAT00000010598" ] }, "reaction_10051999": { "compartment": "compartment_70101", "id": "reaction_10051999", "reactome": "R-BTA-888572", "name": "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10051996", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547" ] }, "reaction_10051989": { "compartment": "compartment_5460", "id": "reaction_10051989", "reactome": "R-BTA-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_880046", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113536" ], "modifiers": [ [ "species_10051986", "catalyst" ] ], "additional_components": [ "E1BDP3", "ENSBTAT00000029203" ] }, "reaction_10033755": { "compartment": "compartment_5460", "id": "reaction_10033755", "reactome": "R-BTA-70609", "name": "glutamine + H2O => glutamate + NH4+ [GLS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113522", "species_113521" ], "products": [ "species_113561", "species_113552" ], "modifiers": [ [ "species_10033752", "catalyst" ] ], "additional_components": [ "E1BHZ6", "ENSBTAT00000012233" ] }, "reaction_10044461": { "compartment": "compartment_876", "id": "reaction_10044461", "reactome": "R-BTA-212642", "name": "L-Glutamine transport into neurons", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_212615", "species_74113" ], "products": [ "species_83910", "species_29472" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014749" ] }, "reaction_10044076": { "compartment": "compartment_984", "id": "reaction_10044076", "reactome": "R-BTA-210404", "name": "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_210382", "species_29804", "species_74113" ], "products": [ "species_74126", "species_29404", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ], [ "species_10044074", "inhibitor" ] ], "additional_components": [ "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455", "ENSBTAT00000028661" ] }, "reaction_10033746": { "compartment": "compartment_70101", "id": "reaction_10033746", "reactome": "R-BTA-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_31633" ], "products": [ "species_29372", "species_29370", "species_29472" ], "modifiers": [ [ "species_10033743", "catalyst" ] ], "additional_components": [ "P15103", "ENSBTAT00000074216" ] }, "reaction_10044086": { "compartment": "compartment_984", "id": "reaction_10044086", "reactome": "R-BTA-210439", "name": "glutamate uptake by astrocytes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382" ], "products": [ "species_29404" ], "modifiers": [ [ "species_10044083", "catalyst" ] ], "additional_components": [] }, "reaction_10054361": { "compartment": "compartment_876", "id": "reaction_10054361", "reactome": "R-BTA-975340", "name": "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054358", "catalyst" ] ], "additional_components": [ "species_428571", "A0A3Q1MA32", "ENSBTAT00000068615", "A0A3Q1MA22", "ENSBTAT00000069238", "F1MHX4", "ENSBTAT00000015688", "Q08E50", "ENSBTAT00000080524", "E1BE96", "ENSBTAT00000017637", "P08219", "ENSBTAT00000009483", "P08220", "ENSBTAT00000023711", "E1BJH4", "ENSBTAT00000060999" ] }, "reaction_10054372": { "compartment": "compartment_876", "id": "reaction_10054372", "reactome": "R-BTA-975449", "name": "GABRR pentamers:GABA transports extracellular Cl- to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054369", "catalyst" ] ], "additional_components": [ "species_428571", "E1B988", "ENSBTAT00000001857" ] }, "reaction_10051085": { "compartment": "compartment_984", "id": "reaction_10051085", "reactome": "R-BTA-500708", "name": "GRIK3 homomer binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050486", "species_210382" ], "products": [ "species_10051083" ], "modifiers": [], "additional_components": [ "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022", "species_210382", "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022" ] }, "reaction_10091067": { "compartment": "compartment_70101", "id": "reaction_10091067", "reactome": "R-BTA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091060", "species_113592" ], "products": [ "species_29370", "species_10091064" ], "modifiers": [ [ "species_10091060", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10091075": { "compartment": "compartment_70101", "id": "reaction_10091075", "reactome": "R-BTA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091071", "species_10037002" ], "products": [ "species_10091073" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010230", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "F6RXS3", "ENSBTAT00000010230" ] }, "reaction_10090547": { "compartment": "compartment_7660", "id": "reaction_10090547", "reactome": "R-BTA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090537" ], "products": [ "species_10090545" ], "modifiers": [], "additional_components": [ "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174" ] }, "reaction_10054318": { "compartment": "compartment_876", "id": "reaction_10054318", "reactome": "R-BTA-975311", "name": "HTR3 pentamers:5HT transport Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10054315", "catalyst" ] ], "additional_components": [ "G3N1Q1", "ENSBTAT00000062928", "F1N4Y2", "ENSBTAT00000014292", "E1BAL4", "ENSBTAT00000056946", "F1N5G0", "ENSBTAT00000055354", "G5E5J6", "ENSBTAT00000022113", "species_209914" ] }, "reaction_10091521": { "compartment": "compartment_876", "id": "reaction_10091521", "reactome": "R-BTA-9648983", "name": "HTR3A pentamer:5HT transports Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10091518", "catalyst" ] ], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10091525": { "compartment": "compartment_876", "id": "reaction_10091525", "reactome": "R-BTA-9649108", "name": "HTR3A pentamer binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091523", "species_114523" ], "products": [ "species_10091518" ], "modifiers": [], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10051521": { "compartment": "compartment_70101", "id": "reaction_10051521", "reactome": "R-BTA-629595", "name": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051518", "catalyst" ] ], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051523": { "compartment": "compartment_984", "id": "reaction_10051523", "reactome": "R-BTA-629596", "name": "Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051516", "species_372533" ], "products": [ "species_10051518" ], "modifiers": [], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051498": { "compartment": "compartment_876", "id": "reaction_10051498", "reactome": "R-BTA-622326", "name": "Activation of highly calcium permeable nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051495", "catalyst" ] ], "additional_components": [ "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10051525": { "compartment": "compartment_984", "id": "reaction_10051525", "reactome": "R-BTA-629599", "name": "Binding of acetylcholine to highly calcium permeable acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051493", "species_372533" ], "products": [ "species_10051495" ], "modifiers": [], "additional_components": [ "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679", "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10065894": { "compartment": "compartment_876", "id": "reaction_10065894", "reactome": "R-BTA-2559456", "name": "TIRAP binds PIP2-rich regions in the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065890", "species_179856" ], "products": [ "species_10065892" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070781", "species_6810412", "A0A3Q1M4J2", "ENSBTAT00000070781" ] }, "reaction_10039217": { "compartment": "compartment_984", "id": "reaction_10039217", "reactome": "R-BTA-166015", "name": "Association of LBP with LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10039213" ], "products": [ "species_10039215" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_166005" ] }, "reaction_10039560": { "compartment": "compartment_70101", "id": "reaction_10039560", "reactome": "R-BTA-168933", "name": "Dimerization of phosphorylated IRF3/IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039558" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10040197": { "compartment": "compartment_70101", "id": "reaction_10040197", "reactome": "R-BTA-177671", "name": "Dimerized phospho-IRF3/IRF7 is transported to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039558" ], "products": [ "species_10040195" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10085369": { "compartment": "compartment_984", "id": "reaction_10085369", "reactome": "R-BTA-8869683", "name": "oxPL binds LBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2186967", "species_10039213" ], "products": [ "species_10085367" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_2186967" ] }, "reaction_10081506": { "compartment": "compartment_984", "id": "reaction_10081506", "reactome": "R-BTA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081502", "species_181015" ], "products": [ "species_10081504" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_181015", "P10103", "ENSBTAT00000024094" ] }, "reaction_10081510": { "compartment": "compartment_984", "id": "reaction_10081510", "reactome": "R-BTA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10081502" ], "products": [ "species_10081508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_166005", "P10103", "ENSBTAT00000024094" ] }, "reaction_10060783": { "compartment": "compartment_17957", "id": "reaction_10060783", "reactome": "R-BTA-1678944", "name": "Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060771" ], "products": [ "species_10060769", "species_10060751", "species_211606", "species_10060763" ], "modifiers": [], "additional_components": [ "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592", "Q95M18", "ENSBTAT00000004364", "A0A3Q1MK24", "ENSBTAT00000079344", "ENSBTAT00000074388" ] }, "reaction_10060785": { "compartment": "compartment_17957", "id": "reaction_10060785", "reactome": "R-BTA-1678998", "name": "Endosomal TLRs pass through the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060757" ], "products": [ "species_10060781" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10060773": { "compartment": "compartment_17957", "id": "reaction_10060773", "reactome": "R-BTA-1678923", "name": "TLR folding by chaperones GP96 and CNPY3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060769", "species_211579", "species_10060749", "species_10060763" ], "products": [ "species_10060771" ], "modifiers": [], "additional_components": [ "Q95M18", "ENSBTAT00000004364", "ENSBTAT00000079344", "ENSBTAT00000074388", "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592" ] }, "reaction_10060759": { "compartment": "compartment_12045", "id": "reaction_10060759", "reactome": "R-BTA-1678921", "name": "Full-length TLR3/7/8/9 binds to UNC93B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060755", "species_10060751" ], "products": [ "species_10060757" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10091739": { "compartment": "compartment_70101", "id": "reaction_10091739", "reactome": "R-BTA-9679029", "name": "C-ter TLR7 dimer binds HCQ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091735", "species_9678628" ], "products": [ "species_10091737" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344" ] }, "reaction_10066168": { "compartment": "compartment_876", "id": "reaction_10066168", "reactome": "R-BTA-2730900", "name": "Activation of TAK1 complex bound to pUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066165", "species_113592" ], "products": [ "species_10066165", "species_29370" ], "modifiers": [ [ "species_10066165", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866" ] }, "reaction_10066059": { "compartment": "compartment_70101", "id": "reaction_10066059", "reactome": "R-BTA-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10066057" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066141": { "compartment": "compartment_876", "id": "reaction_10066141", "reactome": "R-BTA-2730864", "name": "Recruitment of TRAF6 to CBM complex by binding to MALT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066131", "species_10039473" ], "products": [ "species_10066139" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066172": { "compartment": "compartment_876", "id": "reaction_10066172", "reactome": "R-BTA-2730902", "name": "Oligomerization of p-CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066124", "species_10066109" ], "products": [ "species_10066170" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10066127": { "compartment": "compartment_876", "id": "reaction_10066127", "reactome": "R-BTA-2730863", "name": "Phosphorylation of CARMA1 by PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066122", "species_10066057" ], "products": [ "species_29370", "species_10066124" ], "modifiers": [ [ "species_10066057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066147": { "compartment": "compartment_876", "id": "reaction_10066147", "reactome": "R-BTA-2730882", "name": "Phosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043223", "species_113592" ], "products": [ "species_10043202", "species_29370" ], "modifiers": [ [ "species_10065638", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066180": { "compartment": "compartment_876", "id": "reaction_10066180", "reactome": "R-BTA-2730903", "name": "Oligomerization of TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10066139" ], "products": [ "species_10066178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066120": { "compartment": "compartment_876", "id": "reaction_10066120", "reactome": "R-BTA-2730862", "name": "Autophosphorylation of LYN kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066117", "species_113592" ], "products": [ "species_29370", "species_10065617" ], "modifiers": [ [ "species_10066117", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000075171", "ENSBTAT00000075171" ] }, "reaction_10066065": { "compartment": "compartment_876", "id": "reaction_10066065", "reactome": "R-BTA-2730841", "name": "Phosphorylation and activation of VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066061" ], "products": [ "species_29370", "species_10066063" ], "modifiers": [ [ "species_179838", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MQP9", "ENSBTAT00000086853" ] }, "reaction_10066082": { "compartment": "compartment_70101", "id": "reaction_10066082", "reactome": "R-BTA-2730844", "name": "Interaction of GRB2:SOS complex with p-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065484" ], "products": [ "species_10065486" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10066151": { "compartment": "compartment_876", "id": "reaction_10066151", "reactome": "R-BTA-2730886", "name": "Phosphorylation of SHC by SYK kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066149", "species_113592" ], "products": [ "species_29370", "species_10065484" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075224", "ENSBTAT00000075224", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066080": { "compartment": "compartment_876", "id": "reaction_10066080", "reactome": "R-BTA-2730842", "name": "PI3K associates with phosphorylated GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10066076" ], "products": [ "species_10066078" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10066144": { "compartment": "compartment_876", "id": "reaction_10066144", "reactome": "R-BTA-2730870", "name": "Phosphorylation of PIP2 to PIP3 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10066078", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065642": { "compartment": "compartment_876", "id": "reaction_10065642", "reactome": "R-BTA-2454240", "name": "Recruitment of SYK to p-FCERI gamma subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065638", "species_10037584" ], "products": [ "species_10065640" ], "modifiers": [], "additional_components": [ "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066094": { "compartment": "compartment_70101", "id": "reaction_10066094", "reactome": "R-BTA-2730847", "name": "Hydrolysis of PIP2 by PLCG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10066091", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383", "E1BKA6", "ENSBTAT00000020161", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10066052": { "compartment": "compartment_876", "id": "reaction_10066052", "reactome": "R-BTA-2730833", "name": "Phosphorylation of TEC kinases by p-SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066042" ], "products": [ "species_29370", "species_10066047" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "species_179838", "F1MSH3", "ENSBTAT00000046704", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066102": { "compartment": "compartment_876", "id": "reaction_10066102", "reactome": "R-BTA-2730858", "name": "Autophosphorylation of BTK/ITK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066047" ], "products": [ "species_10066099", "species_29370" ], "modifiers": [ [ "species_10066047", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10081085": { "compartment": "compartment_6800424", "id": "reaction_10081085", "reactome": "R-BTA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081071" ], "products": [ "species_10081083" ], "modifiers": [], "additional_components": [ "A0A3Q1LQX2", "ENSBTAT00000078403", "Q05204", "ENSBTAT00000045121", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1N8P4", "ENSBTAT00000066443", "F1MAU4", "ENSBTAT00000047906", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MS24", "ENSBTAT00000075240", "P61285", "ENSBTAT00000081563", "A7YWC4", "ENSBTAT00000012676", "P61585", "ENSBTAT00000005600", "G3N3S2", "ENSBTAT00000064122", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3S5ZPJ1", "ENSBTAT00000017459", "F1MIW8", "ENSBTAT00000018382", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M893", "ENSBTAT00000074148", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1LWC4", "ENSBTAT00000077476", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "F6PZJ9", "ENSBTAT00000084844", "E1BAJ4", "ENSBTAT00000013713", "Q9BDR7", "ENSBTAT00000034054", "A2VDP5", "ENSBTAT00000004547", "A2VDL2", "ENSBTAT00000042889", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "E1B6Z4", "ENSBTAT00000026429", "E1BHT5", "ENSBTAT00000020277", "A5PJK0", "ENSBTAT00000001458", "G5E5S0", "ENSBTAT00000028846", "Q1RMS1", "ENSBTAT00000000367", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1LMZ3", "ENSBTAT00000069125", "A0JN39", "ENSBTAT00000008616", "E1B876", "ENSBTAT00000047448", "Q3LUH2", "ENSBTAT00000032346", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "E1BDF5", "ENSBTAT00000049662", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A7YWC4", "ENSBTAT00000012676", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "Q05204", "ENSBTAT00000045121", "A0JN39", "ENSBTAT00000008616", "A0A3Q1LMZ3", "ENSBTAT00000069125", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MS24", "ENSBTAT00000075240", "A5PJK0", "ENSBTAT00000001458", "Q1RMS1", "ENSBTAT00000000367", "E1B876", "ENSBTAT00000047448", "A2VDP5", "ENSBTAT00000004547", "E1BD53", "ENSBTAT00000035679", "A0A3S5ZPJ1", "ENSBTAT00000017459", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LWC4", "ENSBTAT00000077476", "P61585", "ENSBTAT00000005600", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1N8P4", "ENSBTAT00000066443", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BCF4", "ENSBTAT00000012484", "E1BDF5", "ENSBTAT00000049662", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "F6PZJ9", "ENSBTAT00000084844", "Q9BDR7", "ENSBTAT00000034054", "F1MIW8", "ENSBTAT00000018382", "Q9MYM4", "ENSBTAT00000021325", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1M893", "ENSBTAT00000074148", "F1MAU4", "ENSBTAT00000047906", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "E1BGJ5", "ENSBTAT00000005511" ] }, "reaction_10079949": { "compartment": "compartment_1462052", "id": "reaction_10079949", "reactome": "R-BTA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079839" ], "products": [ "species_10079947" ], "modifiers": [], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A452DI43", "ENSBTAT00000008107", "F1MRP0", "ENSBTAT00000000876", "Q5E987", "ENSBTAT00000027507", "Q0II59", "ENSBTAT00000024203", "P68401", "ENSBTAT00000007398", "Q3SZ62", "ENSBTAT00000032937", "Q3ZCI9", "ENSBTAT00000018917", "P28782", "ENSBTAT00000066555", "E1BI70", "ENSBTAT00000027682", "P79105", "ENSBTAT00000063314", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MFC3", "ENSBTAT00000069599", "A5PKG9", "ENSBTAT00000078914", "Q3T0A3", "ENSBTAT00000063284", "P12763", "ENSBTAT00000000673", "F6QEU6", "ENSBTAT00000007589", "A1A4J1", "ENSBTAT00000056305", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "P10103", "ENSBTAT00000024094", "Q17QP9", "ENSBTAT00000046166", "F1MWU9", "ENSBTAT00000057500", "Q2KJ46", "ENSBTAT00000028608", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F1MHT1", "ENSBTAT00000008518", "Q5E9F9", "ENSBTAT00000065774", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q2KJ25", "ENSBTAT00000003145", "A0A452DJA8", "ENSBTAT00000016346", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A140T8A5", "ENSBTAT00000027348", "A6QQL9", "ENSBTAT00000019085", "F1MWE0", "ENSBTAT00000028983", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "P62935", "ENSBTAT00000015924", "A0A452DIT4", "ENSBTAT00000023325", "Q58DK5", "ENSBTAT00000000315", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1LXA9", "ENSBTAT00000077815", "G3MXC8", "ENSBTAT00000064442", "A0A452DIE3", "ENSBTAT00000000841", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "F1MWE0", "ENSBTAT00000028983", "Q5E9F9", "ENSBTAT00000065774", "Q2KJ25", "ENSBTAT00000003145", "Q3ZCI9", "ENSBTAT00000018917", "F1MRP0", "ENSBTAT00000000876", "Q0II59", "ENSBTAT00000024203", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "P28782", "ENSBTAT00000066555", "P79105", "ENSBTAT00000063314", "A0A3Q1MFC3", "ENSBTAT00000069599", "P68401", "ENSBTAT00000007398", "A5PKG9", "ENSBTAT00000078914", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A452DIE3", "ENSBTAT00000000841", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MBA7", "ENSBTAT00000013758", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "P12763", "ENSBTAT00000000673", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "F1MHT1", "ENSBTAT00000008518", "Q2KJ46", "ENSBTAT00000028608", "Q17QP9", "ENSBTAT00000046166" ] }, "reaction_10080063": { "compartment": "compartment_6799371", "id": "reaction_10080063", "reactome": "R-BTA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080039" ], "products": [ "species_10080061" ], "modifiers": [], "additional_components": [ "A0A3Q1LRA9", "ENSBTAT00000080425", "G3MWP1", "ENSBTAT00000064480", "P33046", "ENSBTAT00000044788", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BPI3", "ENSBTAT00000026661", "Q3ZCL0", "ENSBTAT00000076131", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q2LGB5", "ENSBTAT00000010835", "E1BCU6", "ENSBTAT00000027423", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "A0A3Q1M2J3", "ENSBTAT00000079464", "Q5GN72", "ENSBTAT00000022991", "E1B8Y2", "ENSBTAP00000001395", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZC41", "ENSBTAT00000024335", "F6RMV5", "ENSBTAT00000003618", "G3N0J0", "ENSBTAT00000063400", "E1B6Z6", "ENSBTAT00000018806", "F1MVJ8", "ENSBTAT00000030920", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "E1BFV0", "ENSBTAT00000008650", "P24627", "ENSBTAT00000001704", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F1MRP0", "ENSBTAT00000000876", "A0A3Q1LWX5", "ENSBTAT00000081739", "P80189", "ENSBTAT00000038266", "A0A3Q1MD51", "ENSBTAT00000087110", "F1MW13", "ENSBTAT00000009806", "Q3MHQ1", "ENSBTAT00000007133", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "G3MWP1", "ENSBTAT00000064480", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "A4IF76", "ENSBTAT00000074688", "E1BPI3", "ENSBTAT00000026661", "Q3MHQ1", "ENSBTAT00000007133", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "Q0VCN9", "ENSBTAT00000027602", "F1MRP0", "ENSBTAT00000000876", "Q2LGB5", "ENSBTAT00000010835", "A7YWG4", "ENSBTAT00000009917", "A0A3Q1LRA9", "ENSBTAT00000080425", "E1B6Z6", "ENSBTAT00000018806", "F6RMV5", "ENSBTAT00000003618", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MW13", "ENSBTAT00000009806", "Q3ZCL0", "ENSBTAT00000076131", "A0A3Q1LWX5", "ENSBTAT00000081739", "E1B8Y2", "ENSBTAP00000001395", "E1BFV0", "ENSBTAT00000008650", "Q3ZC41", "ENSBTAT00000024335", "P24627", "ENSBTAT00000001704", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10080719": { "compartment": "compartment_6799351", "id": "reaction_10080719", "reactome": "R-BTA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080687" ], "products": [ "species_10080717" ], "modifiers": [], "additional_components": [ "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MIE9", "ENSBTAT00000079230", "A2VDL2", "ENSBTAT00000042889", "Q29455", "ENSBTAT00000070817", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1MP64", "ENSBTAT00000068539", "Q0VD15", "ENSBTAT00000018402", "A0A3Q1M0A2", "ENSBTAT00000074088", "A0A3Q1LNV7", "ENSBTAT00000083870", "A6H797", "ENSBTAT00000026715", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MFT3", "ENSBTAT00000084806", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BFE2", "ENSBTAT00000020345", "F1N1F5", "ENSBTAT00000021843", "O46521", "ENSBTAT00000067849", "Q58DM3", "ENSBTAT00000008479", "E1BNL9", "ENSBTAT00000027255", "E1BHT5", "ENSBTAT00000020277", "F1N4H1", "ENSBTAT00000055016", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1MIW3", "ENSBTAT00000037423", "P26201", "ENSBTAT00000080828", "A0A3Q1M6K1", "ENSBTAT00000081330", "A0A3Q1MED5", "ENSBTAT00000085048", "P62833", "ENSBTAT00000068678", "F1ME65", "ENSBTAT00000015804", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1M4C7", "ENSBTAT00000078122", "A8E4P3", "ENSBTAT00000052503", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NF89", "ENSBTAT00000076616", "F1MTY9", "ENSBTAT00000047056", "F1MN89", "ENSBTAT00000008168", "F1N680", "ENSBTAT00000026019", "F1MLP3", "ENSBTAT00000008097", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1MQ27", "ENSBTAT00000069303", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q1JPA0", "ENSBTAT00000076578", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "Q32PA1", "ENSBTAT00000002967", "F1N3R7", "ENSBTAT00000026770", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1M288", "ENSBTAT00000085751", "Q6QRN7", "ENSBTAT00000005137", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "P62833", "ENSBTAT00000068678", "Q6QRN7", "ENSBTAT00000005137", "A6H797", "ENSBTAT00000026715", "A0A3Q1M0A2", "ENSBTAT00000074088", "A8E4P3", "ENSBTAT00000052503", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1NF89", "ENSBTAT00000076616", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "F1ME65", "ENSBTAT00000015804", "F1N1F5", "ENSBTAT00000021843", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "Q0VD15", "ENSBTAT00000018402", "Q58DM3", "ENSBTAT00000008479", "Q29455", "ENSBTAT00000070817", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "F1N680", "ENSBTAT00000026019", "Q2KI97", "ENSBTAT00000020710", "F1MIW3", "ENSBTAT00000037423", "F1N3R7", "ENSBTAT00000026770", "F1MLP3", "ENSBTAT00000008097", "F1N4H1", "ENSBTAT00000055016", "F1MZS9", "ENSBTAT00000035230", "P26201", "ENSBTAT00000080828", "F1MTY9", "ENSBTAT00000047056", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1MN89", "ENSBTAT00000008168", "A0A3Q1M2M7", "ENSBTAT00000073921", "A0A3Q1M4C7", "ENSBTAT00000078122", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1M6K1", "ENSBTAT00000081330", "Q17QQ1", "ENSBTAT00000047833", "O46521", "ENSBTAT00000067849", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1MIE9", "ENSBTAT00000079230", "Q1JPA0", "ENSBTAT00000076578", "E1BHT5", "ENSBTAT00000020277", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1M288", "ENSBTAT00000085751", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10079391": { "compartment": "compartment_6800173", "id": "reaction_10079391", "reactome": "R-BTA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079319" ], "products": [ "species_10079389" ], "modifiers": [], "additional_components": [ "A7YWG4", "ENSBTAT00000009917", "Q0VCN9", "ENSBTAT00000027602", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LMG1", "ENSBTAT00000083687", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5W1C4", "ENSBTAT00000080090", "Q5GN72", "ENSBTAT00000022991", "F1MVJ8", "ENSBTAT00000030920", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "G3N0J0", "ENSBTAT00000063400", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A140T831", "ENSBTAT00000000683", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1M739", "ENSBTAT00000077529", "A0A452DIT4", "ENSBTAT00000023325", "E1B8Y2", "ENSBTAP00000001395", "A7YWU9", "ENSBTAT00000028731", "P25326", "ENSBTAT00000022774", "P24627", "ENSBTAT00000001704", "E1BCU6", "ENSBTAT00000027423", "P01035", "ENSBTAT00000000790", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P33046", "ENSBTAT00000044788", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q3ZBE7", "ENSBTAT00000032525", "P80189", "ENSBTAT00000038266", "A0A140T8A5", "ENSBTAT00000027348", "A4IF76", "ENSBTAT00000074688", "Q5EA55", "ENSBTAT00000069302", "Q3ZCL0", "ENSBTAT00000076131", "P02070", "ENSBTAT00000057323", "A0A3Q1M2R9", "ENSBTAT00000085538", "Q5EA55", "ENSBTAT00000069302", "A7YWU9", "ENSBTAT00000028731", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A140T8A5", "ENSBTAT00000027348", "Q5W1C4", "ENSBTAT00000080090", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "P25326", "ENSBTAT00000022774", "A0A452DIT4", "ENSBTAT00000023325", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MGS0", "ENSBTAT00000074118", "P01035", "ENSBTAT00000000790", "A0A140T831", "ENSBTAT00000000683", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1B8Y2", "ENSBTAP00000001395", "Q3ZCL0", "ENSBTAT00000076131", "P24627", "ENSBTAT00000001704", "P02070", "ENSBTAT00000057323", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZBE7", "ENSBTAT00000032525", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10079199": { "compartment": "compartment_876", "id": "reaction_10079199", "reactome": "R-BTA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079131" ], "products": [ "species_10079197" ], "modifiers": [], "additional_components": [ "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1NF89", "ENSBTAT00000076616", "Q0VD15", "ENSBTAT00000018402", "Q9TTY5", "ENSBTAT00000038757", "A0JN39", "ENSBTAT00000008616", "A0A452DIB1", "ENSBTAT00000013018", "P08037", "ENSBTAT00000020286", "F1MDR7", "ENSBTAT00000003865", "A6QLS9", "ENSBTAT00000001303", "E1BK38", "ENSBTAT00000061018", "E1BCF4", "ENSBTAT00000012484", "P11023", "ENSBTAT00000014062", "A0A3Q1MS24", "ENSBTAT00000075240", "Q08DC2", "ENSBTAT00000075871", "A7YWC4", "ENSBTAT00000012676", "F1MNI4", "ENSBTAT00000018777", "F6PZJ9", "ENSBTAT00000084844", "F1MCK4", "ENSBTAT00000054453", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1LZT3", "ENSBTAT00000069265", "Q673L2", "ENSBTAT00000027807", "Q2KI99", "ENSBTAT00000071484", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1MHJ9", "ENSBTAT00000086833", "E1BI37", "ENSBTAT00000035878", "Q3LUH2", "ENSBTAT00000032346", "F1MHH9", "ENSBTAT00000029116", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N0T3", "ENSBTAT00000023242", "E1BPL8", "ENSBTAT00000002681", "E1B876", "ENSBTAT00000047448", "P61585", "ENSBTAT00000005600", "E1BD53", "ENSBTAT00000035679", "Q1RMI2", "ENSBTAT00000000453", "F1MIE6", "ENSBTAT00000037678", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1MB09", "ENSBTAT00000068383", "A5PJK0", "ENSBTAT00000001458", "E1BGJ5", "ENSBTAT00000005511", "Q1JPA0", "ENSBTAT00000076578", "F1MTR1", "ENSBTAT00000001190", "F1MHH9", "ENSBTAT00000029116", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A6QLS9", "ENSBTAT00000001303", "F1MTR1", "ENSBTAT00000001190", "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "Q673L2", "ENSBTAT00000027807", "F1MCK4", "ENSBTAT00000054453", "F6PZJ9", "ENSBTAT00000084844", "P11023", "ENSBTAT00000014062", "Q08DC2", "ENSBTAT00000075871", "A0A452DIB1", "ENSBTAT00000013018", "E1BPL8", "ENSBTAT00000002681", "A0A3Q1NF89", "ENSBTAT00000076616", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1MNI4", "ENSBTAT00000018777", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MB09", "ENSBTAT00000068383", "A0A3Q1NNM6", "ENSBTAT00000081334", "A7YWC4", "ENSBTAT00000012676", "Q0VD15", "ENSBTAT00000018402", "A0JN39", "ENSBTAT00000008616", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1MJS9", "ENSBTAT00000013320", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1MS24", "ENSBTAT00000075240", "Q1RMI2", "ENSBTAT00000000453", "E1BI37", "ENSBTAT00000035878", "A5PJK0", "ENSBTAT00000001458", "E1B876", "ENSBTAT00000047448", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "E1BK38", "ENSBTAT00000061018", "P61585", "ENSBTAT00000005600", "Q2KI99", "ENSBTAT00000071484", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BCF4", "ENSBTAT00000012484", "F1MIE6", "ENSBTAT00000037678", "A0A3Q1M0R0", "ENSBTAT00000081916", "P08037", "ENSBTAT00000020286", "Q1JPA0", "ENSBTAT00000076578", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10078929": { "compartment": "compartment_6798757", "id": "reaction_10078929", "reactome": "R-BTA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078881" ], "products": [ "species_10078927" ], "modifiers": [], "additional_components": [ "A0A3Q1MCZ8", "ENSBTAT00000067584", "P61223", "ENSBTAT00000019575", "Q2KIW2", "ENSBTAT00000000146", "Q02827", "ENSBTAT00000024209", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1MDC6", "ENSBTAT00000075241", "F1N3T5", "ENSBTAT00000021761", "A8E4P3", "ENSBTAT00000052503", "F1MAU4", "ENSBTAT00000047906", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BK38", "ENSBTAT00000061018", "Q3T0Y8", "ENSBTAT00000033040", "G3MY77", "ENSBTAT00000065645", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q29455", "ENSBTAT00000070817", "A4IFF5", "ENSBTAT00000026308", "F1ME65", "ENSBTAT00000015804", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1N680", "ENSBTAT00000026019", "A5PJY9", "ENSBTAT00000020644", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1NHB1", "ENSBTAT00000080189", "Q05204", "ENSBTAT00000045121", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q0II86", "ENSBTAT00000027666", "Q9XSK2", "ENSBTAT00000015829", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "P08037", "ENSBTAT00000020286", "A0A3Q1MDS4", "ENSBTAT00000073232", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q3T0Y8", "ENSBTAT00000033040", "F1MAU4", "ENSBTAT00000047906", "F1ME65", "ENSBTAT00000015804", "Q9MYM4", "ENSBTAT00000021325", "P61223", "ENSBTAT00000019575", "A0A3Q1N0X5", "ENSBTAT00000068372", "A0A3Q1MDC6", "ENSBTAT00000075241", "A8E4P3", "ENSBTAT00000052503", "P08037", "ENSBTAT00000020286", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "E1BI37", "ENSBTAT00000035878", "Q2KIW2", "ENSBTAT00000000146", "A0A3Q1NHB1", "ENSBTAT00000080189", "F1N3T5", "ENSBTAT00000021761", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1N8P4", "ENSBTAT00000066443", "G3MY77", "ENSBTAT00000065645", "Q9XSK2", "ENSBTAT00000015829", "E1BK38", "ENSBTAT00000061018", "A4IFF5", "ENSBTAT00000026308", "Q02827", "ENSBTAT00000024209", "A0A3Q1MDS4", "ENSBTAT00000073232", "Q0II86", "ENSBTAT00000027666", "F1N680", "ENSBTAT00000026019", "F1MDR7", "ENSBTAT00000003865", "Q29455", "ENSBTAT00000070817", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q05204", "ENSBTAT00000045121", "F1MTK4", "ENSBTAT00000001250", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10081265": { "compartment": "compartment_984", "id": "reaction_10081265", "reactome": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081245" ], "products": [ "species_10081263" ], "modifiers": [], "additional_components": [ "A0A3Q1LTT9", "ENSBTAT00000073013", "Q5E9F9", "ENSBTAT00000065774", "Q3SWY3", "ENSBTAT00000025179", "F1MWE0", "ENSBTAT00000028983", "Q3SZ62", "ENSBTAT00000032937", "F1MHT1", "ENSBTAT00000008518", "A0A452DI43", "ENSBTAT00000008107", "F1MNS8", "ENSBTAT00000061310", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "Q2KJ46", "ENSBTAT00000028608", "Q3T0A3", "ENSBTAT00000063284", "A0A140T8A5", "ENSBTAT00000027348", "P34955", "ENSBTAT00000072441", "P02070", "ENSBTAT00000057323", "Q5W1C4", "ENSBTAT00000080090", "Q3ZBE7", "ENSBTAT00000032525", "P68401", "ENSBTAT00000007398", "A1A4J1", "ENSBTAT00000056305", "Q3ZCI9", "ENSBTAT00000018917", "E1BFV0", "ENSBTAT00000008650", "G3N0V2", "ENSBTAT00000065029", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "Q29RY7", "ENSBTAT00000012815", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A3Q1MD51", "ENSBTAT00000087110", "A0A452DJA8", "ENSBTAT00000016346", "A6QQL9", "ENSBTAT00000019085", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "Q27975", "ENSBTAT00000017500", "P01035", "ENSBTAT00000000790", "P62935", "ENSBTAT00000015924", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "A0A452DIT4", "ENSBTAT00000023325", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "Q2KJ25", "ENSBTAT00000003145", "Q17QP9", "ENSBTAT00000046166", "A4IFQ6", "ENSBTAT00000018403", "P07688", "ENSBTAT00000036795", "P25326", "ENSBTAT00000022774", "E1BB52", "ENSBTAT00000002003", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A452DJ01", "ENSBTAT00000011678", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1LPS7", "ENSBTAT00000084564", "E1BA23", "ENSBTAT00000021018", "F1MMD5", "ENSBTAT00000008020", "F1MXZ0", "ENSBTAT00000023218", "A3KMY8", "ENSBTAT00000000941", "A6QLZ3", "ENSBTAT00000010988", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q2KJ25", "ENSBTAT00000003145", "F6RMV5", "ENSBTAT00000003618", "Q3ZCI9", "ENSBTAT00000018917", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "P01035", "ENSBTAT00000000790", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1MGS0", "ENSBTAT00000074118", "A6QLZ3", "ENSBTAT00000010988", "P68401", "ENSBTAT00000007398", "A3KMY8", "ENSBTAT00000000941", "A0A3Q1M2J3", "ENSBTAT00000079464", "F1MNS8", "ENSBTAT00000061310", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "E1BFV0", "ENSBTAT00000008650", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A3Q1M5Y2", "ENSBTAT00000084883", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "P34955", "ENSBTAT00000072441", "P25326", "ENSBTAT00000022774", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LXA9", "ENSBTAT00000077815", "Q58DK5", "ENSBTAT00000000315", "A0A3Q1MD51", "ENSBTAT00000087110", "A5D984", "ENSBTAT00000047412", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "Q5W1C4", "ENSBTAT00000080090", "Q29RY7", "ENSBTAT00000012815", "Q5E9F9", "ENSBTAT00000065774", "Q27975", "ENSBTAT00000017500", "F1MWE0", "ENSBTAT00000028983", "G3N0V2", "ENSBTAT00000065029", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "A0A452DJ01", "ENSBTAT00000011678", "F1MHT1", "ENSBTAT00000008518", "P02070", "ENSBTAT00000057323", "A4IFQ6", "ENSBTAT00000018403", "Q2KJ46", "ENSBTAT00000028608", "Q3ZBE7", "ENSBTAT00000032525", "P07688", "ENSBTAT00000036795", "Q17QP9", "ENSBTAT00000046166", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10080435": { "compartment": "compartment_1470028", "id": "reaction_10080435", "reactome": "R-BTA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080307" ], "products": [ "species_10080433" ], "modifiers": [], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1MGY9", "ENSBTAT00000022716", "A0A3Q1MPJ7", "ENSBTAT00000067144", "H7BWW2", "ENSBTAT00000048411", "F1MU84", "ENSBTAT00000006001", "A7MBA2", "ENSBTAT00000006754", "A6QPT4", "ENSBTAT00000067752", "O77834", "ENSBTAT00000006383", "E1BI70", "ENSBTAT00000027682", "P80189", "ENSBTAT00000038266", "A0A3Q1LYV0", "ENSBTAT00000070714", "Q5GN72", "ENSBTAT00000022991", "A6QLB7", "ENSBTAT00000017775", "G3MWP1", "ENSBTAT00000064480", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A3Q1MRR6", "ENSBTAT00000078659", "A7YWU9", "ENSBTAT00000028731", "Q3MHM5", "ENSBTAT00000074704", "Q17QI1", "ENSBTAT00000065281", "A0A3Q1LUG9", "ENSBTAT00000076880", "E1BPI3", "ENSBTAT00000026661", "O46415", "ENSBTAT00000009965", "Q2LGB5", "ENSBTAT00000010835", "F1N7I6", "ENSBTAT00000024550", "F1N1V6", "ENSBTAT00000005121", "F1MU24", "ENSBTAT00000006069", "Q2KJD0", "ENSBTAT00000009158", "A0A3Q1LQA6", "ENSBTAT00000072426", "E1BFP1", "ENSBTAT00000000304", "A7YWG4", "ENSBTAT00000009917", "Q29451", "ENSBTAT00000070599", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "E1BI28", "ENSBTAT00000029099", "E1BAD2", "ENSBTAT00000054741", "A0A452DJ87", "ENSBTAT00000039203", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1ML33", "ENSBTAT00000073654", "A0A3Q1LMW6", "ENSBTAT00000073103", "E1B8B5", "ENSBTAT00000053165", "A0A3Q1LTS9", "ENSBTAT00000068563", "F1MMS7", "ENSBTAT00000065330", "A0A3Q1LY36", "ENSBTAT00000068245", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LIW8", "ENSBTAT00000073870", "Q3ZCI9", "ENSBTAT00000018917", "P79345", "ENSBTAT00000029271", "F6QH17", "ENSBTAT00000026526", "F1MUP9", "ENSBTAT00000009715", "F1MGC2", "ENSBTAT00000036230", "G3N2H4", "ENSBTAT00000063121", "F6QIT9", "ENSBTAT00000019270", "A3KMY8", "ENSBTAT00000000941", "P04272", "ENSBTAT00000012655", "A0A3Q1MS42", "ENSBTAT00000074408", "Q2KJ64", "ENSBTAT00000016461", "F1N048", "ENSBTAT00000004411", "A6QLZ3", "ENSBTAT00000010988", "E1B725", "ENSBTAT00000025636", "Q2KIM0", "ENSBTAT00000042970", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "F1N5H2", "ENSBTAT00000002297", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "A0A3Q1LYV0", "ENSBTAT00000070714", "F1MXZ0", "ENSBTAT00000023218", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "F1MU84", "ENSBTAT00000006001", "F1MGY9", "ENSBTAT00000022716", "A6QLZ3", "ENSBTAT00000010988", "P04272", "ENSBTAT00000012655", "F1N5H2", "ENSBTAT00000002297", "E1BAD2", "ENSBTAT00000054741", "H7BWW2", "ENSBTAT00000048411", "A3KMY8", "ENSBTAT00000000941", "G3N2H4", "ENSBTAT00000063121", "E1BI28", "ENSBTAT00000029099", "A0A452DJ87", "ENSBTAT00000039203", "A0A3Q1MPJ7", "ENSBTAT00000067144", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LUG9", "ENSBTAT00000076880", "F6QH17", "ENSBTAT00000026526", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "F1MUP9", "ENSBTAT00000009715", "A0A3Q1ML33", "ENSBTAT00000073654", "E1B8B5", "ENSBTAT00000053165", "F1MMS7", "ENSBTAT00000065330", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1LMW6", "ENSBTAT00000073103", "A0A3Q1LTS9", "ENSBTAT00000068563", "A0A3Q1LY36", "ENSBTAT00000068245", "F1N1V6", "ENSBTAT00000005121", "Q3MHM5", "ENSBTAT00000074704", "Q2KJD0", "ENSBTAT00000009158", "Q17QI1", "ENSBTAT00000065281", "Q2KJ64", "ENSBTAT00000016461", "A7MBA2", "ENSBTAT00000006754", "O77834", "ENSBTAT00000006383", "Q2LGB5", "ENSBTAT00000010835", "Q2KIM0", "ENSBTAT00000042970", "A7YWU9", "ENSBTAT00000028731", "E1B725", "ENSBTAT00000025636", "A6QLB7", "ENSBTAT00000017775", "E1BPI3", "ENSBTAT00000026661", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "F6QIT9", "ENSBTAT00000019270", "F1N048", "ENSBTAT00000004411", "P80189", "ENSBTAT00000038266", "A0A3Q1MS42", "ENSBTAT00000074408", "G3MWP1", "ENSBTAT00000064480", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "Q29451", "ENSBTAT00000070599", "Q3ZCI9", "ENSBTAT00000018917", "A7YWG4", "ENSBTAT00000009917", "A6QPT4", "ENSBTAT00000067752", "F1MU24", "ENSBTAT00000006069", "F1N7I6", "ENSBTAT00000024550", "E1BFP1", "ENSBTAT00000000304", "A0A3Q1LQA6", "ENSBTAT00000072426", "A0A3Q1LIW8", "ENSBTAT00000073870", "F1MGC2", "ENSBTAT00000036230", "P79345", "ENSBTAT00000029271", "O46415", "ENSBTAT00000009965" ] }, "reaction_10079653": { "compartment": "compartment_6799713", "id": "reaction_10079653", "reactome": "R-BTA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079613" ], "products": [ "species_10079651" ], "modifiers": [], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230", "F1N0T3", "ENSBTAT00000023242", "E1BFE2", "ENSBTAT00000020345", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "Q9TTY5", "ENSBTAT00000038757", "Q58DM3", "ENSBTAT00000008479", "A0A3Q1MP64", "ENSBTAT00000068539", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "O46521", "ENSBTAT00000067849", "A8E4P3", "ENSBTAT00000052503", "P61285", "ENSBTAT00000081563", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1MED5", "ENSBTAT00000085048", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "G5E5N4", "ENSBTAT00000026431", "Q9MYM4", "ENSBTAT00000021325", "Q32LK2", "ENSBTAT00000022077", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "A0JN39", "ENSBTAT00000008616", "A2VDL2", "ENSBTAT00000042889", "G3X6D0", "ENSBTAT00000004058", "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A5D7R9", "ENSBTAT00000012897", "Q3ZBG1", "ENSBTAT00000023671", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1N4H1", "ENSBTAT00000055016", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1M2M7", "ENSBTAT00000073921", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MQ27", "ENSBTAT00000069303", "Q32PA1", "ENSBTAT00000002967", "G3N3S2", "ENSBTAT00000064122", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1LZT3", "ENSBTAT00000069265", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "A8E4P3", "ENSBTAT00000052503", "Q9BDR7", "ENSBTAT00000034054", "Q9MYM4", "ENSBTAT00000021325", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0JN39", "ENSBTAT00000008616", "Q58DM3", "ENSBTAT00000008479", "Q3LUH2", "ENSBTAT00000032346", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "Q2KI97", "ENSBTAT00000020710", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q3ZBG1", "ENSBTAT00000023671", "A5D7R9", "ENSBTAT00000012897", "O46521", "ENSBTAT00000067849", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "Q32LK2", "ENSBTAT00000022077", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1MIE9", "ENSBTAT00000079230", "E1BHT5", "ENSBTAT00000020277", "G3X6D0", "ENSBTAT00000004058", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1NDL5", "ENSBTAT00000086325", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10072392": { "compartment": "compartment_876", "id": "reaction_10072392", "reactome": "R-BTA-5621366", "name": "SYK binds to p-Y65,Y76-FCER1G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072358", "species_10037584" ], "products": [ "species_10072390" ], "modifiers": [], "additional_components": [ "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10072395": { "compartment": "compartment_876", "id": "reaction_10072395", "reactome": "R-BTA-5621370", "name": "SYK autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072390", "species_113592" ], "products": [ "species_29370", "species_10072360" ], "modifiers": [ [ "species_10072390", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10084636": { "compartment": "compartment_876", "id": "reaction_10084636", "reactome": "R-BTA-8858500", "name": "CLEC10A binds Tn-MUC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084632", "species_10084616" ], "products": [ "species_10084634" ], "modifiers": [], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000054378", "E1BJL5", "ENSBTAT00000054378", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897" ] }, "reaction_10072364": { "compartment": "compartment_876", "id": "reaction_10072364", "reactome": "R-BTA-5621347", "name": "PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072362" ], "products": [ "species_10072360", "species_10072008" ], "modifiers": [], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000074574" ] }, "reaction_10072383": { "compartment": "compartment_876", "id": "reaction_10072383", "reactome": "R-BTA-5621355", "name": "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072378" ], "products": [ "species_10072358", "species_29370" ], "modifiers": [ [ "species_10072380", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "CHEBI:28808", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10072388": { "compartment": "compartment_876", "id": "reaction_10072388", "reactome": "R-BTA-5621363", "name": "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072385" ], "products": [ "species_29370", "species_10072362" ], "modifiers": [ [ "species_10072385", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574" ] }, "reaction_10072374": { "compartment": "compartment_876", "id": "reaction_10072374", "reactome": "R-BTA-5621353", "name": "CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072370", "species_5621138" ], "products": [ "species_10072372" ], "modifiers": [], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016", "species_5621138", "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016" ] }, "reaction_10072057": { "compartment": "compartment_876", "id": "reaction_10072057", "reactome": "R-BTA-5607753", "name": "CARD9 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072055", "species_10071996" ], "products": [ "species_10071998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072011": { "compartment": "compartment_876", "id": "reaction_10072011", "reactome": "R-BTA-5607735", "name": "p-Y753,Y759-PLCG2 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10072008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10072045": { "compartment": "compartment_876", "id": "reaction_10072045", "reactome": "R-BTA-5607750", "name": "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072038", "species_113592" ], "products": [ "species_29370", "species_10072043" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "CHEBI:37671", "F1N2F3", "ENSBTAT00000085840", "F1N2F3", "ENSBTAT00000085840", "CHEBI:37671", "ENSBTAT00000011767" ] }, "reaction_10072061": { "compartment": "compartment_876", "id": "reaction_10072061", "reactome": "R-BTA-5607755", "name": "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072059" ], "products": [ "species_10072008" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10072015": { "compartment": "compartment_876", "id": "reaction_10072015", "reactome": "R-BTA-5607737", "name": "BCL10 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072000", "species_10043291" ], "products": [ "species_10072013" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072032": { "compartment": "compartment_876", "id": "reaction_10072032", "reactome": "R-BTA-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072004" ], "products": [ "species_10072019" ], "modifiers": [], "additional_components": [ "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072002": { "compartment": "compartment_876", "id": "reaction_10072002", "reactome": "R-BTA-5607733", "name": "BCL10 binds CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071998", "species_10043291" ], "products": [ "species_10072000" ], "modifiers": [], "additional_components": [ "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072053": { "compartment": "compartment_876", "id": "reaction_10072053", "reactome": "R-BTA-5607751", "name": "TRAF6 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072049", "species_10039473" ], "products": [ "species_10072051" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000021630", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10072006": { "compartment": "compartment_876", "id": "reaction_10072006", "reactome": "R-BTA-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070610", "species_112275" ], "products": [ "species_10072004" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072022": { "compartment": "compartment_876", "id": "reaction_10072022", "reactome": "R-BTA-5607740", "name": "PKC-delta phosphorylates CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072017" ], "products": [ "species_29370", "species_10071996" ], "modifiers": [ [ "species_10072019", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10054649": { "compartment": "compartment_876", "id": "reaction_10054649", "reactome": "R-BTA-977602", "name": "Complement factor I binds to MCP, CR1:C4b, C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054645", "species_10054492" ], "products": [ "species_10054647" ], "modifiers": [], "additional_components": [ "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10054494": { "compartment": "compartment_984", "id": "reaction_10054494", "reactome": "R-BTA-976801", "name": "Complement factor I complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054490", "species_10054488" ], "products": [ "species_10054492" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076236", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236" ] }, "reaction_10066238": { "compartment": "compartment_984", "id": "reaction_10066238", "reactome": "R-BTA-2855047", "name": "Hydrolysis of internal thioester in C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10039322" ], "products": [ "species_10066236" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019" ] }, "reaction_10090400": { "compartment": "compartment_984", "id": "reaction_10090400", "reactome": "R-BTA-9021306", "name": "C1-Inh binds and inactivates C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084018" ], "products": [ "species_10084063" ], "modifiers": [], "additional_components": [ "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "E1BMJ0", "ENSBTAT00000021638", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10055971": { "compartment": "compartment_876", "id": "reaction_10055971", "reactome": "R-BTA-1006169", "name": "Factor H binds host cell surface markers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006146", "species_10054484" ], "products": [ "species_10055969" ], "modifiers": [], "additional_components": [ "CHEBI:24505", "species_1006168", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "CHEBI:24505", "species_1006168" ] }, "reaction_10087797": { "compartment": "compartment_876", "id": "reaction_10087797", "reactome": "R-BTA-8951486", "name": "CD46 binds C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054643", "species_10054624" ], "products": [ "species_10054645" ], "modifiers": [], "additional_components": [ "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "ENSBTAT00000073079", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10084020": { "compartment": "compartment_984", "id": "reaction_10084020", "reactome": "R-BTA-8852266", "name": "C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039462", "species_10038209" ], "products": [ "species_10084018" ], "modifiers": [], "additional_components": [ "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "ENSBTAT00000021638", "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10054678": { "compartment": "compartment_876", "id": "reaction_10054678", "reactome": "R-BTA-977615", "name": "Factor I inactivates MCP/CR1-bound C4b/C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054647" ], "products": [ "species_10054675", "species_10054624", "species_10054657", "species_10054492" ], "modifiers": [ [ "species_10054647", "catalyst" ] ], "additional_components": [ "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "ENSBTAT00000073079", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10039465": { "compartment": "compartment_984", "id": "reaction_10039465", "reactome": "R-BTA-166753", "name": "Conversion of C4 into C4a and C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039302" ], "products": [ "species_10039310", "species_10039322" ], "modifiers": [ [ "species_10039462", "catalyst" ] ], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10039778": { "compartment": "compartment_984", "id": "reaction_10039778", "reactome": "R-BTA-173626", "name": "Activation of C1r", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039759" ], "products": [ "species_10039765" ], "modifiers": [ [ "species_10039759", "catalyst" ], [ "species_10039776", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "species_74016", "C4T8B4", "ENSBTAT00000018469", "species_1524071", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146" ] }, "reaction_10039782": { "compartment": "compartment_876", "id": "reaction_10039782", "reactome": "R-BTA-173631", "name": "Activation of C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039765" ], "products": [ "species_10039462" ], "modifiers": [ [ "species_10039765", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10054736": { "compartment": "compartment_876", "id": "reaction_10054736", "reactome": "R-BTA-981713", "name": "C4b binds to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039322", "species_983438" ], "products": [ "species_10054643" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10053134": { "compartment": "compartment_17906", "id": "reaction_10053134", "reactome": "R-BTA-936564", "name": "NLRX1 inhibits MAVS-DDX58 interaction.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10053130" ], "products": [ "species_10053132" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000016601", "F1MUU5", "ENSBTAT00000016601", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10053122": { "compartment": "compartment_70101", "id": "reaction_10053122", "reactome": "R-BTA-936563", "name": "ISGylation of DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10053118" ], "products": [ "species_10053120" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10053095": { "compartment": "compartment_7660", "id": "reaction_10053095", "reactome": "R-BTA-936380", "name": "Interaction of PIN1 with p-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053091", "species_10053086" ], "products": [ "species_10053093" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056088": { "compartment": "compartment_7660", "id": "reaction_10056088", "reactome": "R-BTA-1028820", "name": "Formation of VAF (virus-activated factor) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056080", "species_10053054" ], "products": [ "species_10056086" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053058": { "compartment": "compartment_7660", "id": "reaction_10053058", "reactome": "R-BTA-933536", "name": "p-IRF7 dimer interacts with coactivator CBP/p300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040193", "species_10053054" ], "products": [ "species_10053056" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10092318": { "compartment": "compartment_17906", "id": "reaction_10092318", "reactome": "R-BTA-9709842", "name": "MAVS binds TOMM70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10070254" ], "products": [ "species_10092316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000019001", "Q08E34", "ENSBTAT00000019001", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10056090": { "compartment": "compartment_70101", "id": "reaction_10056090", "reactome": "R-BTA-1028821", "name": "Dimerization of Phospho IRF3 or phospho IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039556", "species_10039554", "species_10056078" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10056082": { "compartment": "compartment_13231", "id": "reaction_10056082", "reactome": "R-BTA-1028816", "name": "Translocation of phosphorylated IRF3,IRF7 dimers into nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556", "species_10039554", "species_10056078" ], "products": [ "species_10056080", "species_10040193", "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056084": { "compartment": "compartment_7660", "id": "reaction_10056084", "reactome": "R-BTA-1028817", "name": "CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053054", "species_10040189" ], "products": [ "species_10056076" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10066559": { "compartment": "compartment_70101", "id": "reaction_10066559", "reactome": "R-BTA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066555", "species_3134861" ], "products": [ "species_10066557" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008082", "Q05B79", "ENSBTAT00000008082" ] }, "reaction_10090837": { "compartment": "compartment_13231", "id": "reaction_10090837", "reactome": "R-BTA-9604487", "name": "p-IRF7:p-IRF7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10066536": { "compartment": "compartment_70101", "id": "reaction_10066536", "reactome": "R-BTA-3134804", "name": "STING ubiquitination by TRIM32 or TRIM56", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10061500" ], "products": [ "species_10066530", "species_10055114" ], "modifiers": [ [ "species_10061500", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801", "ENSBTAT00000071484", "ENSBTAT00000022801", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10061502": { "compartment": "compartment_70101", "id": "reaction_10061502", "reactome": "R-BTA-1964496", "name": "STING binds TRIM32 or TRIM56 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055114", "species_10061498" ], "products": [ "species_10061500" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022801", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10066551": { "compartment": "compartment_70101", "id": "reaction_10066551", "reactome": "R-BTA-3134946", "name": "DDX41 ubiquitination by TRIM21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054900", "species_10033408", "species_10066540" ], "products": [ "species_10066548" ], "modifiers": [ [ "species_10054900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018459", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "Q7YRV4", "ENSBTAT00000018459", "ENSBTAT00000018459" ] }, "reaction_10066608": { "compartment": "compartment_70101", "id": "reaction_10066608", "reactome": "R-BTA-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10066604" ], "products": [ "species_10066606" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "E1BIN9", "ENSBTAT00000011748", "species_874088" ] }, "reaction_10065388": { "compartment": "compartment_70101", "id": "reaction_10065388", "reactome": "R-BTA-2395992", "name": "p-T,4S-IRF3 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039546" ], "products": [ "species_10039556" ], "modifiers": [], "additional_components": [ "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10063376": { "compartment": "compartment_70101", "id": "reaction_10063376", "reactome": "R-BTA-2032396", "name": "Dimerized phospho-IRF3 migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556" ], "products": [ "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10067225": { "compartment": "compartment_70101", "id": "reaction_10067225", "reactome": "R-BTA-3249372", "name": "p-S407,Y641-STAT6 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067208" ], "products": [ "species_10067210" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067229": { "compartment": "compartment_70101", "id": "reaction_10067229", "reactome": "R-BTA-3249378", "name": "STING recruits TBK1 and STAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_10046560", "species_10065393" ], "products": [ "species_10067227" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067231": { "compartment": "compartment_70101", "id": "reaction_10067231", "reactome": "R-BTA-3249379", "name": "p-S407-STAT6 is phosphorylated at Tyr641", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067220", "species_113592" ], "products": [ "species_29370", "species_10067208" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "ENSBTAT00000008311" ] }, "reaction_10067233": { "compartment": "compartment_70101", "id": "reaction_10067233", "reactome": "R-BTA-3249390", "name": "TBK1 is phosphorylated within STING:TBK1:STAT6 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10067227" ], "products": [ "species_10067218", "species_29370" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067216": { "compartment": "compartment_70101", "id": "reaction_10067216", "reactome": "R-BTA-3249370", "name": "p-S407,Y641-STAT6 dimer migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067210" ], "products": [ "species_10067214" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067223": { "compartment": "compartment_70101", "id": "reaction_10067223", "reactome": "R-BTA-3249371", "name": "TBK1 phosphorylates STAT6 at Ser407", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067218", "species_113592" ], "products": [ "species_10067220", "species_29370", "species_10065404" ], "modifiers": [ [ "species_10067218", "catalyst" ] ], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065402": { "compartment": "compartment_70101", "id": "reaction_10065402", "reactome": "R-BTA-2396002", "name": "TBK1 is phosphorylated within STING:TBK1:IRF3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065395", "species_113592" ], "products": [ "species_29370", "species_10065400" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065407": { "compartment": "compartment_70101", "id": "reaction_10065407", "reactome": "R-BTA-2396007", "name": "IRF3 is phosphorylated by TBK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065400" ], "products": [ "species_29370", "species_10065404", "species_10039546" ], "modifiers": [ [ "species_10065400", "catalyst" ] ], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10066880": { "compartment": "compartment_12045", "id": "reaction_10066880", "reactome": "R-BTA-3244643", "name": "STING binds cyclic GMP-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3244587", "species_10065409" ], "products": [ "species_10066878" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "species_3244587" ] }, "reaction_10090019": { "compartment": "compartment_70101", "id": "reaction_10090019", "reactome": "R-BTA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8982080", "species_10066540" ], "products": [ "species_10090017" ], "modifiers": [], "additional_components": [ "species_2395973", "CHEBI:47037", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "species_2395973", "CHEBI:47037" ] }, "reaction_10065413": { "compartment": "compartment_12045", "id": "reaction_10065413", "reactome": "R-BTA-2396009", "name": "STING binds c-di-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065409", "species_2395973" ], "products": [ "species_10065411" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "species_2395973", "Q2KI99", "ENSBTAT00000071484" ] }, "reaction_10066532": { "compartment": "compartment_12045", "id": "reaction_10066532", "reactome": "R-BTA-3134800", "name": "STING dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061498" ], "products": [ "species_10065409" ], "modifiers": [ [ "species_10066530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "ENSBTAT00000071484" ] }, "reaction_10081432": { "compartment": "compartment_984", "id": "reaction_10081432", "reactome": "R-BTA-6803063", "name": "RNASEs bind bacterial LPS, PGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_6803074" ], "products": [ "species_10081430" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "CHEBI:55478", "species_6789198", "species_166005", "CHEBI:55478", "species_6789198", "species_166005", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10082008": { "compartment": "compartment_984", "id": "reaction_10082008", "reactome": "R-BTA-6807565", "name": "GNLY is transferred to the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939" ], "products": [ "species_10082006" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "ENSBTAT00000083501" ] }, "reaction_10056539": { "compartment": "compartment_984", "id": "reaction_10056539", "reactome": "R-BTA-1222685", "name": "Cathelicidin LL-37 binds to bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056535", "species_8879165" ], "products": [ "species_10056537" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044788", "P33046", "ENSBTAT00000044788" ] }, "reaction_10082012": { "compartment": "compartment_1222282", "id": "reaction_10082012", "reactome": "R-BTA-6807578", "name": "GNLY binds the bacterial cell surface in the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082006", "species_8931784" ], "products": [ "species_10082010" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10083100": { "compartment": "compartment_984", "id": "reaction_10083100", "reactome": "R-BTA-6813626", "name": "LEAP2 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083096", "species_8931784" ], "products": [ "species_10083098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025186", "species_1462049", "species_1462049", "Q95JC3", "ENSBTAT00000025186" ] }, "reaction_10070906": { "compartment": "compartment_984", "id": "reaction_10070906", "reactome": "R-BTA-5229273", "name": "LCN2:2,5DHBA binds Fe3+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070902", "species_912516" ], "products": [ "species_10070904" ], "modifiers": [], "additional_components": [ "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806", "species_917966", "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806" ] }, "reaction_10056416": { "compartment": "compartment_1222282", "id": "reaction_10056416", "reactome": "R-BTA-1222491", "name": "Lactoferrin scavenges iron ions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2101051", "species_10056412", "species_1222611" ], "products": [ "species_10056414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001704", "species_917966", "P24627", "ENSBTAT00000001704", "species_2101051" ] }, "reaction_10078759": { "compartment": "compartment_984", "id": "reaction_10078759", "reactome": "R-BTA-6798489", "name": "S100A7 or S100A7A binds Zn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078755", "species_158417" ], "products": [ "species_10078757" ], "modifiers": [], "additional_components": [ "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "species_29426", "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838" ] }, "reaction_10082004": { "compartment": "compartment_984", "id": "reaction_10082004", "reactome": "R-BTA-6807144", "name": "HTN1,HTN3 or HTN5 binds the bacterial anionic surface ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081994", "species_8931784" ], "products": [ "species_10082002" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077381", "species_1462049", "species_1462049", "A0A3Q1LX31", "ENSBTAT00000077381" ] }, "reaction_10081559": { "compartment": "compartment_984", "id": "reaction_10081559", "reactome": "R-BTA-6804527", "name": "INTL1 binds bacterial glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081555", "species_6804535" ], "products": [ "species_10081557" ], "modifiers": [], "additional_components": [ "species_74016", "G3N3R4", "ENSBTAT00000064812", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "species_74016", "G3N3R4", "ENSBTAT00000064812" ] }, "reaction_10081943": { "compartment": "compartment_984", "id": "reaction_10081943", "reactome": "R-BTA-6806732", "name": "GNLY binds the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939", "species_8931784" ], "products": [ "species_10081941" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10082967": { "compartment": "compartment_5083403", "id": "reaction_10082967", "reactome": "R-BTA-6810643", "name": "EPPIN protein complex binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082963" ], "products": [ "species_10082965" ], "modifiers": [], "additional_components": [ "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324", "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324" ] }, "reaction_10084683": { "compartment": "compartment_984", "id": "reaction_10084683", "reactome": "R-BTA-8862300", "name": "LYZ binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10079373" ], "products": [ "species_10084681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038266", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10080842": { "compartment": "compartment_984", "id": "reaction_10080842", "reactome": "R-BTA-6799977", "name": "PGLYRP2 hydrolyzes bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080839", "species_109276" ], "products": [ "species_10080837", "species_6799970", "species_6799975" ], "modifiers": [ [ "species_10080837", "catalyst" ], [ "species_158417", "catalyst" ] ], "additional_components": [ "species_6789198", "E1BH94", "ENSBTAT00000047024", "E1BH94", "ENSBTAT00000047024", "CHEBI:28881", "species_1678743", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10080844": { "compartment": "compartment_984", "id": "reaction_10080844", "reactome": "R-BTA-6799981", "name": "PGLYRP2 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080837", "species_6789198" ], "products": [ "species_10080839" ], "modifiers": [], "additional_components": [ "E1BH94", "ENSBTAT00000047024", "species_6789198", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10084686": { "compartment": "compartment_984", "id": "reaction_10084686", "reactome": "R-BTA-8862320", "name": "LYZ hydrolyzes peptidoglycans in the bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10084681" ], "products": [ "species_6788991", "species_6788982" ], "modifiers": [ [ "species_10084681", "catalyst" ] ], "additional_components": [ "P80189", "ENSBTAT00000038266", "species_6789198", "species_1236715", "CHEBI:21615", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10058388": { "compartment": "compartment_17963", "id": "reaction_10058388", "reactome": "R-BTA-1462023", "name": "Pre-pro-defensins are cleaved to remove the signal peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058328" ], "products": [ "species_10058386" ], "modifiers": [], "additional_components": [ "A0A3Q1M0J5", "ENSBTAT00000086067", "O02775", "ENSBTAT00000009756", "A0A3Q1ME63", "ENSBTAT00000074783", "P25068", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "Q50JB9", "ENSBTAT00000072863", "G3MWU3", "ENSBTAT00000074783", "Q5W5I5", "ENSBTAT00000069740", "A0A452DIQ0", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "Q28880", "ENSBTAT00000050266", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10081410": { "compartment": "compartment_984", "id": "reaction_10081410", "reactome": "R-BTA-6801808", "name": "REG3A,REG3G binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10081389" ], "products": [ "species_10081408" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "P23132", "ENSBTAT00000086119", "species_6789198" ] }, "reaction_10082183": { "compartment": "compartment_984", "id": "reaction_10082183", "reactome": "R-BTA-6809521", "name": "BPIF binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082179" ], "products": [ "species_10082181" ], "modifiers": [], "additional_components": [ "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454", "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454" ] }, "reaction_10081404": { "compartment": "compartment_984", "id": "reaction_10081404", "reactome": "R-BTA-6801766", "name": "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081399" ], "products": [ "species_10081389", "species_10081401" ], "modifiers": [ [ "species_10058556", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000028731" ] }, "reaction_10080831": { "compartment": "compartment_984", "id": "reaction_10080831", "reactome": "R-BTA-6799959", "name": "PGLYRP3,4 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10080827" ], "products": [ "species_10080829" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "A0A3Q1M1U5", "ENSBTAT00000078335", "A0A3Q1M1U5", "ENSBTAT00000078335", "species_6789198" ] }, "reaction_10081406": { "compartment": "compartment_984", "id": "reaction_10081406", "reactome": "R-BTA-6801776", "name": "REG3A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081389", "species_8931784" ], "products": [ "species_10081391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "species_1462049", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10087601": { "compartment": "compartment_984", "id": "reaction_10087601", "reactome": "R-BTA-8948027", "name": "RNASEs bind bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_8931784" ], "products": [ "species_10087599" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "species_1462049", "species_1462049", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10081397": { "compartment": "compartment_984", "id": "reaction_10081397", "reactome": "R-BTA-6801762", "name": "REG3A oligomerize to form a pore complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081391" ], "products": [ "species_10081395" ], "modifiers": [ [ "species_166005", "inhibitor" ] ], "additional_components": [ "species_1462049", "P23132", "ENSBTAT00000086119", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10081385": { "compartment": "compartment_984", "id": "reaction_10081385", "reactome": "R-BTA-6801687", "name": "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081382" ], "products": [ "species_10056535" ], "modifiers": [ [ "species_10080371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044788", "ENSBTAT00000044788", "ENSBTAT00000064845" ] }, "reaction_10082977": { "compartment": "compartment_984", "id": "reaction_10082977", "reactome": "R-BTA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10082971" ], "products": [ "species_10082975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056512", "A1A4Q6", "ENSBTAT00000056512", "species_166005" ] }, "reaction_10083106": { "compartment": "compartment_984", "id": "reaction_10083106", "reactome": "R-BTA-6813659", "name": "ELANE, CTSG or PRTN3 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10083102" ], "products": [ "species_10083104" ], "modifiers": [], "additional_components": [ "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480", "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10084706": { "compartment": "compartment_984", "id": "reaction_10084706", "reactome": "R-BTA-8862771", "name": "PLA2G2A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059808", "species_8931784" ], "products": [ "species_10084704" ], "modifiers": [], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "species_1462049", "species_1462049", "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10051836": { "compartment": "compartment_70101", "id": "reaction_10051836", "reactome": "R-BTA-879221", "name": "PSTPIP1 binds Pyrin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051824", "species_10051832" ], "products": [ "species_10051834" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q8", "ENSBTAT00000085633", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1M2Q8", "ENSBTAT00000085633" ] }, "reaction_10077919": { "compartment": "compartment_21994", "id": "reaction_10077919", "reactome": "R-BTA-6789031", "name": "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077916", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10084322": { "compartment": "compartment_984", "id": "reaction_10084322", "reactome": "R-BTA-8855490", "name": "Lactoperoxidase (LPO) produces OSCN-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_8855492" ], "products": [ "species_109276", "species_8855489" ], "modifiers": [ [ "species_10084319", "catalyst" ] ], "additional_components": [ "P80025", "ENSBTAT00000016986", "CHEBI:55376" ] }, "reaction_10086405": { "compartment": "compartment_1222282", "id": "reaction_10086405", "reactome": "R-BTA-8933635", "name": "Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_1470067", "species_6789221" ], "products": [ "species_8933637", "species_1222475" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077924": { "compartment": "compartment_1222282", "id": "reaction_10077924", "reactome": "R-BTA-6789126", "name": "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077926": { "compartment": "compartment_21994", "id": "reaction_10077926", "reactome": "R-BTA-6789136", "name": "Myeloperoxidase (MPO) binds to the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077914", "species_983438" ], "products": [ "species_10077916" ], "modifiers": [], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376", "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077921": { "compartment": "compartment_1222282", "id": "reaction_10077921", "reactome": "R-BTA-6789092", "name": "NOX2 generates superoxide anion from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_1222561" ], "products": [ "species_1222461", "species_70106", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10077904": { "compartment": "compartment_70101", "id": "reaction_10077904", "reactome": "R-BTA-6788999", "name": "HV1-mediated H+ transfer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10077901", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10047907": { "compartment": "compartment_70101", "id": "reaction_10047907", "reactome": "R-BTA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10047904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069366" ] }, "reaction_10056531": { "compartment": "compartment_1222693", "id": "reaction_10056531", "reactome": "R-BTA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10056528", "catalyst" ] ], "additional_components": [ "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "O97681", "ENSBTAT00000009563", "E1BGJ7", "ENSBTAT00000005588", "Q1RMS1", "ENSBTAT00000000367", "A0A3Q1MS24", "ENSBTAT00000075240" ] }, "reaction_10063368": { "compartment": "compartment_876", "id": "reaction_10063368", "reactome": "R-BTA-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10063365", "catalyst" ] ], "additional_components": [ "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10049304": { "compartment": "compartment_70101", "id": "reaction_10049304", "reactome": "R-BTA-432909", "name": "Interaction of Plectin with Integrin beta 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043", "species_10044490" ], "products": [ "species_10049302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082561", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRS3", "ENSBTAT00000082561" ] }, "reaction_10075165": { "compartment": "compartment_7660", "id": "reaction_10075165", "reactome": "R-BTA-5686475", "name": "SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075149", "species_10075161" ], "products": [ "species_10075163" ], "modifiers": [], "additional_components": [ "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10075151": { "compartment": "compartment_7660", "id": "reaction_10075151", "reactome": "R-BTA-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075143", "species_10075139" ], "products": [ "species_10075149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053203", "G3N153", "ENSBTAT00000065898", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10050458": { "compartment": "compartment_70101", "id": "reaction_10050458", "reactome": "R-BTA-451056", "name": "Microtubule-independent trafficking of connexons to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050452" ], "products": [ "species_10050456" ], "modifiers": [], "additional_components": [ "A2VE67", "ENSBTAT00000023167", "A2VE67", "ENSBTAT00000023167" ] }, "reaction_10040857": { "compartment": "compartment_70101", "id": "reaction_10040857", "reactome": "R-BTA-190782", "name": "Budding of connexon-containing transport vesicles from the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040855" ], "products": [ "species_10040800" ], "modifiers": [], "additional_components": [ "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398" ] }, "reaction_10040842": { "compartment": "compartment_70101", "id": "reaction_10040842", "reactome": "R-BTA-190520", "name": "Association of Golgi transport vesicles with microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10040800" ], "products": [ "species_10040840" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398", "species_29438", "species_29420" ] }, "reaction_10036729": { "compartment": "compartment_7660", "id": "reaction_10036729", "reactome": "R-BTA-110231", "name": "Cleavage of uracil by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036724" ], "products": [ "species_10036726", "species_29554" ], "modifiers": [ [ "species_10036724", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036716": { "compartment": "compartment_7660", "id": "reaction_10036716", "reactome": "R-BTA-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036713" ], "products": [ "species_29692", "species_10036706" ], "modifiers": [ [ "species_10036713", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036767": { "compartment": "compartment_7660", "id": "reaction_10036767", "reactome": "R-BTA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036764" ], "products": [ "species_10036757", "species_5636006" ], "modifiers": [ [ "species_10036764", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10036736": { "compartment": "compartment_7660", "id": "reaction_10036736", "reactome": "R-BTA-110232", "name": "Cleavage of thymine by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036733" ], "products": [ "species_10036726", "species_29692" ], "modifiers": [ [ "species_10036733", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036709": { "compartment": "compartment_7660", "id": "reaction_10036709", "reactome": "R-BTA-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036702" ], "products": [ "species_10036706", "species_29554" ], "modifiers": [ [ "species_10036702", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036743": { "compartment": "compartment_7660", "id": "reaction_10036743", "reactome": "R-BTA-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036740" ], "products": [ "species_10036706", "species_110233" ], "modifiers": [ [ "species_10036740", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10089640": { "compartment": "compartment_7660", "id": "reaction_10089640", "reactome": "R-BTA-9008822", "name": "PPM1D dephosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10089633" ], "products": [ "species_10086640", "species_113541" ], "modifiers": [ [ "species_10089637", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000012404" ] }, "reaction_10086716": { "compartment": "compartment_7660", "id": "reaction_10086716", "reactome": "R-BTA-8939688", "name": "SCF(SKP2) complex binds RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10086712" ], "products": [ "species_10086714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089679": { "compartment": "compartment_70101", "id": "reaction_10089679", "reactome": "R-BTA-9009308", "name": "STUB1 polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10089672" ], "products": [ "species_10055082", "species_10089674" ], "modifiers": [ [ "species_10089672", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000025473", "ENSBTAT00000066565", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089681": { "compartment": "compartment_70101", "id": "reaction_10089681", "reactome": "R-BTA-9009309", "name": "RUNX2 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089668", "species_10055082" ], "products": [ "species_10089672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000025473", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10086724": { "compartment": "compartment_7660", "id": "reaction_10086724", "reactome": "R-BTA-8939706", "name": "SCF(SKP2) polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10086714" ], "products": [ "species_10086719", "species_10086712" ], "modifiers": [ [ "species_10086714", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089610": { "compartment": "compartment_7660", "id": "reaction_10089610", "reactome": "R-BTA-9008412", "name": "CDK4 phosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10086640" ], "products": [ "species_113582", "species_10089605" ], "modifiers": [ [ "species_10089607", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10089357": { "compartment": "compartment_7660", "id": "reaction_10089357", "reactome": "R-BTA-8985343", "name": "RUNX2 binds SOX9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10089353" ], "products": [ "species_10089355" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000084141", "A0A3Q1MN22", "ENSBTAT00000084141", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10074877": { "compartment": "compartment_7660", "id": "reaction_10074877", "reactome": "R-BTA-5685319", "name": "CX3 complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10074873" ], "products": [ "species_10074875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000013145", "A0A452DJ33", "ENSBTAT00000013145", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10065177": { "compartment": "compartment_7660", "id": "reaction_10065177", "reactome": "R-BTA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064869", "species_10064891" ], "products": [ "species_10065175" ], "modifiers": [], "additional_components": [ "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064904": { "compartment": "compartment_7660", "id": "reaction_10064904", "reactome": "R-BTA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064897", "species_113671", "species_113685" ], "products": [ "species_10064901", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10064897", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067", "species_71067", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067" ] }, "reaction_10065563": { "compartment": "compartment_7660", "id": "reaction_10065563", "reactome": "R-BTA-2429719", "name": "MCPH1 sequesters condensin II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065559", "species_10064869", "species_10050283" ], "products": [ "species_10065561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068774", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1M8A5", "ENSBTAT00000068774" ] }, "reaction_10065201": { "compartment": "compartment_7660", "id": "reaction_10065201", "reactome": "R-BTA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065186" ], "products": [ "species_113582", "species_10065198" ], "modifiers": [ [ "species_10065186", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "F1MPS0", "ENSBTAT00000039478", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064733": { "compartment": "compartment_7660", "id": "reaction_10064733", "reactome": "R-BTA-2168079", "name": "MASTL (GWL) phosphorylates ARPP19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10064715" ], "products": [ "species_113582", "species_10064723" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "A0A3Q1NDP8", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1NDP8", "ENSBTAT00000075206", "ENSBTAT00000022950" ] }, "reaction_10065572": { "compartment": "compartment_7660", "id": "reaction_10065572", "reactome": "R-BTA-2430535", "name": "MASTL phosphorylates ENSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065567" ], "products": [ "species_113582", "species_10065570" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009379", "ENSBTAT00000009379", "ENSBTAT00000022950" ] }, "reaction_10066345": { "compartment": "compartment_70101", "id": "reaction_10066345", "reactome": "R-BTA-2984258", "name": "NEK9 phosphorylates NEK6/NEK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066322", "species_113592" ], "products": [ "species_10066342", "species_29370" ], "modifiers": [ [ "species_10066322", "catalyst" ] ], "additional_components": [ "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10066324": { "compartment": "compartment_70101", "id": "reaction_10066324", "reactome": "R-BTA-2980720", "name": "NEK9 binds NEK6/NEK7 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066309", "species_10066320" ], "products": [ "species_10066322" ], "modifiers": [], "additional_components": [ "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10070705": { "compartment": "compartment_13231", "id": "reaction_10070705", "reactome": "R-BTA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10069478", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005" ] }, "reaction_10069491": { "compartment": "compartment_13231", "id": "reaction_10069491", "reactome": "R-BTA-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10069470" ], "products": [ "species_113550", "species_10069478" ], "modifiers": [ [ "species_10069488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LKP8", "ENSBTAT00000083005", "Q1RMV9", "ENSBTAT00000025896", "Q3ZBP2", "ENSBTAT00000046962" ] }, "reaction_10065095": { "compartment": "compartment_20699", "id": "reaction_10065095", "reactome": "R-BTA-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065087" ], "products": [ "species_10065092", "species_29370" ], "modifiers": [ [ "species_10065087", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10038371": { "compartment": "compartment_5460", "id": "reaction_10038371", "reactome": "R-BTA-159566", "name": "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159447" ], "products": [ "species_29374", "species_159564" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10038354": { "compartment": "compartment_5460", "id": "reaction_10038354", "reactome": "R-BTA-159443", "name": "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159446" ], "products": [ "species_159448", "species_159450", "species_159447" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10039520": { "compartment": "compartment_17906", "id": "reaction_10039520", "reactome": "R-BTA-168848", "name": "tBID binds to inactive BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037233" ], "products": [ "species_10037620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10037237": { "compartment": "compartment_17906", "id": "reaction_10037237", "reactome": "R-BTA-114263", "name": "Oligomerization of BAK at the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037233" ], "products": [ "species_10037235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10037622": { "compartment": "compartment_17906", "id": "reaction_10037622", "reactome": "R-BTA-139895", "name": "tBID activates BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037620" ], "products": [ "species_10037269", "species_10037233" ], "modifiers": [], "additional_components": [ "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000000549" ] }, "reaction_10047809": { "compartment": "compartment_876", "id": "reaction_10047809", "reactome": "R-BTA-400434", "name": "GPR40 (Free fatty acid receptor 1, FFAR1) binds fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10058908": { "compartment": "compartment_12045", "id": "reaction_10058908", "reactome": "R-BTA-1482679", "name": "PA is hydrolysed to 1-acyl LPA by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10077777": { "compartment": "compartment_70101", "id": "reaction_10077777", "reactome": "R-BTA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10077774", "catalyst" ] ], "additional_components": [ "A0A3Q1MMR4", "ENSBTAT00000085985", "F1MSS2", "ENSBTAT00000017473" ] }, "reaction_10058896": { "compartment": "compartment_70101", "id": "reaction_10058896", "reactome": "R-BTA-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10058834": { "compartment": "compartment_17906", "id": "reaction_10058834", "reactome": "R-BTA-1482548", "name": "1-acyl LPA is acylated to PA by AGPAT5 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500580" ], "products": [ "species_1500590", "species_76194" ], "modifiers": [ [ "species_10058831", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006476" ] }, "reaction_10059860": { "compartment": "compartment_984", "id": "reaction_10059860", "reactome": "R-BTA-1602446", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10088649": { "compartment": "compartment_17906", "id": "reaction_10088649", "reactome": "R-BTA-8954398", "name": "PLD6 dimer hydrolyses cardiolipin to PA and PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189422", "species_8954419" ], "products": [ "species_8954401", "species_1500590" ], "modifiers": [ [ "species_10088630", "catalyst" ], [ "species_10088647", "catalyst" ] ], "additional_components": [ "E1BE10", "ENSBTAT00000010531", "F1MNB3", "ENSBTAT00000043938", "Q1JPG0", "ENSBTAT00000014090" ] }, "reaction_10086248": { "compartment": "compartment_984", "id": "reaction_10086248", "reactome": "R-BTA-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8878780" ], "products": [ "species_8878776", "species_109277" ], "modifiers": [ [ "species_10086245", "catalyst" ] ], "additional_components": [ "species_29426", "species_74016", "F1N2M5", "ENSBTAT00000043359" ] }, "reaction_10058923": { "compartment": "compartment_17906", "id": "reaction_10058923", "reactome": "R-BTA-1482695", "name": "G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_76194", "species_1500580" ], "modifiers": [ [ "species_10058920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015359" ] }, "reaction_10035786": { "compartment": "compartment_12045", "id": "reaction_10035786", "reactome": "R-BTA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10035783", "catalyst" ] ], "additional_components": [ "Q95JH2", "ENSBTAT00000083979", "A6H7D4", "ENSBTAT00000007532", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1LJ33", "ENSBTAT00000076188", "G5E5P6", "ENSBTAT00000087371", "E1BGF8", "ENSBTAT00000023396", "A0A3S5ZPU2", "ENSBTAT00000006476", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10058858": { "compartment": "compartment_17906", "id": "reaction_10058858", "reactome": "R-BTA-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500590" ], "products": [ "species_1500580", "species_1524103" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059114": { "compartment": "compartment_12045", "id": "reaction_10059114", "reactome": "R-BTA-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10059111", "catalyst" ] ], "additional_components": [ "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10051264": { "compartment": "compartment_12045", "id": "reaction_10051264", "reactome": "R-BTA-549112", "name": "G3P is acylated to 1-acyl LPA by AGPAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_1500604", "species_76194" ], "modifiers": [ [ "species_10035769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007532" ] }, "reaction_10035812": { "compartment": "compartment_70101", "id": "reaction_10035812", "reactome": "R-BTA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10035809", "catalyst" ] ], "additional_components": [ "A0A452DJJ3", "ENSBTAT00000021683", "A0A3Q1MUU4", "ENSBTAT00000057343" ] }, "reaction_10044235": { "compartment": "compartment_17960", "id": "reaction_10044235", "reactome": "R-BTA-211959", "name": "CYP3A43 6b-hydroxylates TEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044177", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044255": { "compartment": "compartment_17960", "id": "reaction_10044255", "reactome": "R-BTA-211968", "name": "CYP2W1 oxidises INDOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_216547" ], "products": [ "species_113519", "species_113564", "species_216598" ], "modifiers": [ [ "species_10044252", "catalyst" ] ], "additional_components": [ "F1MXW1", "ENSBTAT00000023544" ] }, "reaction_10044158": { "compartment": "compartment_17960", "id": "reaction_10044158", "reactome": "R-BTA-211874", "name": "CYP2S1 4-hydroxylates atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044155", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024282" ] }, "reaction_10044242": { "compartment": "compartment_17960", "id": "reaction_10044242", "reactome": "R-BTA-211960", "name": "CYP2U1 19-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_216620", "species_113519", "species_113564" ], "modifiers": [ [ "species_10044239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017246" ] }, "reaction_10044247": { "compartment": "compartment_17960", "id": "reaction_10044247", "reactome": "R-BTA-211962", "name": "CYP4F11 16-hydroxylates 3OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_216621", "species_113601" ], "products": [ "species_113519", "species_113564", "species_216612" ], "modifiers": [ [ "species_10044244", "catalyst" ] ], "additional_components": [ "A0A3Q1MCJ2", "ENSBTAT00000073532" ] }, "reaction_10078408": { "compartment": "compartment_70101", "id": "reaction_10078408", "reactome": "R-BTA-6793685", "name": "Ubiquitinated TP53 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675" ], "products": [ "species_10078406" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10033535": { "compartment": "compartment_7660", "id": "reaction_10033535", "reactome": "R-BTA-69685", "name": "CHEK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10033532", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000006518" ] }, "reaction_10076341": { "compartment": "compartment_7660", "id": "reaction_10076341", "reactome": "R-BTA-5693609", "name": "ATM phosphorylates TP53 at S15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000040104" ] }, "reaction_10081470": { "compartment": "compartment_7660", "id": "reaction_10081470", "reactome": "R-BTA-6803719", "name": "TP53 binds ZNF385A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081466" ], "products": [ "species_10081468" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070196", "A0A3Q1M6W9", "ENSBTAT00000070196", "P67939", "ENSBTAT00000001420" ] }, "reaction_10057800": { "compartment": "compartment_7660", "id": "reaction_10057800", "reactome": "R-BTA-1363303", "name": "p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056559" ], "products": [ "species_10057798" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057804": { "compartment": "compartment_7660", "id": "reaction_10057804", "reactome": "R-BTA-1363306", "name": "p130 (RBL2) binds Cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056543" ], "products": [ "species_10057802" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057808": { "compartment": "compartment_7660", "id": "reaction_10057808", "reactome": "R-BTA-1363311", "name": "p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056608" ], "products": [ "species_10057806" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057812": { "compartment": "compartment_7660", "id": "reaction_10057812", "reactome": "R-BTA-1363314", "name": "p107 (RBL1) binds CyclinE/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056606" ], "products": [ "species_10057810" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000015333", "E1BMR3", "ENSBTAT00000015333", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10037433": { "compartment": "compartment_70101", "id": "reaction_10037433", "reactome": "R-BTA-114558", "name": "Thrombin-activated PARs activate Gq", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037427" ], "products": [ "species_10037431", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10037353": { "compartment": "compartment_70101", "id": "reaction_10037353", "reactome": "R-BTA-114552", "name": "Thrombin-activated PARs activate G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037346" ], "products": [ "species_10037350", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10047880": { "compartment": "compartment_70101", "id": "reaction_10047880", "reactome": "R-BTA-418172", "name": "F2R binds ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10047872" ], "products": [ "species_10047878" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "ENSBTAT00000026902", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092299": { "compartment": "compartment_984", "id": "reaction_10092299", "reactome": "R-BTA-9708859", "name": "Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092295" ], "products": [ "species_10047872", "species_10092297" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026902", "ENSBTAT00000026902", "ENSBTAT00000026902", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10037580": { "compartment": "compartment_984", "id": "reaction_10037580", "reactome": "R-BTA-114697", "name": "Activated thrombin (factor IIa) cleaves PAR3,4, activating them", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037563" ], "products": [ "species_10037569", "species_10037342" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10047886": { "compartment": "compartment_70101", "id": "reaction_10047886", "reactome": "R-BTA-418200", "name": "SRC-1 bound to ARRB2 is not activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047884" ], "products": [ "species_10047884" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078", "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10041337": { "compartment": "compartment_5460", "id": "reaction_10041337", "reactome": "R-BTA-193713", "name": "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193785", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193747", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041339": { "compartment": "compartment_5460", "id": "reaction_10041339", "reactome": "R-BTA-193719", "name": "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193708", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193716", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041341": { "compartment": "compartment_70101", "id": "reaction_10041341", "reactome": "R-BTA-193727", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041343": { "compartment": "compartment_17951", "id": "reaction_10041343", "reactome": "R-BTA-193736", "name": "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041361": { "compartment": "compartment_70101", "id": "reaction_10041361", "reactome": "R-BTA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041363": { "compartment": "compartment_5460", "id": "reaction_10041363", "reactome": "R-BTA-193787", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193777", "species_113600" ], "products": [ "species_113563", "species_193782", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041365": { "compartment": "compartment_70101", "id": "reaction_10041365", "reactome": "R-BTA-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_193724", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041367": { "compartment": "compartment_5460", "id": "reaction_10041367", "reactome": "R-BTA-193792", "name": "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193720", "species_113529", "species_113600" ], "products": [ "species_193708", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041335": { "compartment": "compartment_70101", "id": "reaction_10041335", "reactome": "R-BTA-193711", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041193": { "compartment": "compartment_70101", "id": "reaction_10041193", "reactome": "R-BTA-192061", "name": "CYP46A1 24-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_192060", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041190", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068208" ] }, "reaction_10041353": { "compartment": "compartment_70101", "id": "reaction_10041353", "reactome": "R-BTA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041355": { "compartment": "compartment_17951", "id": "reaction_10041355", "reactome": "R-BTA-193763", "name": "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193793" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041357": { "compartment": "compartment_70101", "id": "reaction_10041357", "reactome": "R-BTA-193766", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041359": { "compartment": "compartment_5460", "id": "reaction_10041359", "reactome": "R-BTA-193780", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193782", "species_113600" ], "products": [ "species_193785", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041217": { "compartment": "compartment_70101", "id": "reaction_10041217", "reactome": "R-BTA-192178", "name": "CYP39A1 7-hydroxylates 24OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192060", "species_70106", "species_29368", "species_29364" ], "products": [ "species_192189", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041214", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004736" ] }, "reaction_10041345": { "compartment": "compartment_5460", "id": "reaction_10041345", "reactome": "R-BTA-193737", "name": "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193716", "species_113600" ], "products": [ "species_193757", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041347": { "compartment": "compartment_70101", "id": "reaction_10041347", "reactome": "R-BTA-193743", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041349": { "compartment": "compartment_70101", "id": "reaction_10041349", "reactome": "R-BTA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041351": { "compartment": "compartment_70101", "id": "reaction_10041351", "reactome": "R-BTA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10047659": { "compartment": "compartment_70101", "id": "reaction_10047659", "reactome": "R-BTA-399939", "name": "Autophosphorylation of PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047616" ], "products": [ "species_29370", "species_10047656" ], "modifiers": [ [ "species_10047616", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047763": { "compartment": "compartment_70101", "id": "reaction_10047763", "reactome": "R-BTA-399952", "name": "Phosphorylation of LIMK-1 by PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047656", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10047618": { "compartment": "compartment_70101", "id": "reaction_10047618", "reactome": "R-BTA-399930", "name": "Activation of PAK by Rac1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047612", "species_10047592" ], "products": [ "species_10047616", "species_10047614" ], "modifiers": [], "additional_components": [ "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047753": { "compartment": "compartment_70101", "id": "reaction_10047753", "reactome": "R-BTA-399951", "name": "Phosphorylation of CRMPs by GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047714", "species_113592" ], "products": [ "species_10047750", "species_29370" ], "modifiers": [ [ "species_10041574", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "ENSBTAT00000056446" ] }, "reaction_10047717": { "compartment": "compartment_70101", "id": "reaction_10047717", "reactome": "R-BTA-399944", "name": "Phosphorylation of CRMPs by Cdk5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047695", "species_10047675" ], "products": [ "species_10047714", "species_29370" ], "modifiers": [ [ "species_10047695", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859" ] }, "reaction_10047735": { "compartment": "compartment_70101", "id": "reaction_10047735", "reactome": "R-BTA-399947", "name": "Tyrosine phosphorylation of CRMPs by Fes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047586", "species_113592", "species_10047675" ], "products": [ "species_10047732", "species_29370" ], "modifiers": [ [ "species_10043848", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "ENSBTAT00000003828" ] }, "reaction_10045244": { "compartment": "compartment_876", "id": "reaction_10045244", "reactome": "R-BTA-373748", "name": "SEMA4D interacts with CD72", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045240" ], "products": [ "species_10045242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000015162", "E1BPB4", "ENSBTAT00000015162", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10045236": { "compartment": "compartment_876", "id": "reaction_10045236", "reactome": "R-BTA-373746", "name": "SEMA4D interacts with CD45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045228" ], "products": [ "species_10045234" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000013320", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10089713": { "compartment": "compartment_984", "id": "reaction_10089713", "reactome": "R-BTA-9010815", "name": "SLITs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089709", "species_2299699" ], "products": [ "species_10089711" ], "modifiers": [], "additional_components": [ "F1MLJ7", "ENSBTAT00000061059", "species_2299699", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10090179": { "compartment": "compartment_984", "id": "reaction_10090179", "reactome": "R-BTA-9014812", "name": "ROBOs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043663", "species_2299699" ], "products": [ "species_10090177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061264", "species_2299699", "F1N739", "ENSBTAT00000061264" ] }, "reaction_10045517": { "compartment": "compartment_70101", "id": "reaction_10045517", "reactome": "R-BTA-376141", "name": "Interaction of ABL with ROBO1:SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10045513" ], "products": [ "species_10045515" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "ENSBTAT00000080797", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10049024": { "compartment": "compartment_70101", "id": "reaction_10049024", "reactome": "R-BTA-428888", "name": "Phosphorylation of ROBO1 by ABL kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10045515" ], "products": [ "species_29370", "species_10049021" ], "modifiers": [ [ "species_10045515", "catalyst" ] ], "additional_components": [ "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10089397": { "compartment": "compartment_876", "id": "reaction_10089397", "reactome": "R-BTA-8986258", "name": "SLIT2:ROBO1 binds CXCR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10089393" ], "products": [ "species_10089395" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048935": { "compartment": "compartment_876", "id": "reaction_10048935", "reactome": "R-BTA-428518", "name": "Glypican-1 (GPC1) binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048931", "species_10043667" ], "products": [ "species_10048933" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "ENSBTAT00000061059", "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10043671": { "compartment": "compartment_876", "id": "reaction_10043671", "reactome": "R-BTA-204364", "name": "ROBO1 binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043667", "species_10043663" ], "products": [ "species_10043669" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061059", "ENSBTAT00000061264", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048951": { "compartment": "compartment_70101", "id": "reaction_10048951", "reactome": "R-BTA-428534", "name": "Recruitment of Profilin by Ena/VASP proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048947", "species_10043457" ], "products": [ "species_10048949" ], "modifiers": [], "additional_components": [ "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10047449": { "compartment": "compartment_70101", "id": "reaction_10047449", "reactome": "R-BTA-392051", "name": "Recruitment of Grb2 to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047443", "species_10035485" ], "products": [ "species_10047447" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000006216", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10047455": { "compartment": "compartment_70101", "id": "reaction_10047455", "reactome": "R-BTA-392053", "name": "SOS binds Grb2 bound to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047447", "species_10035489" ], "products": [ "species_10047453" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000015471", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10047458": { "compartment": "compartment_70101", "id": "reaction_10047458", "reactome": "R-BTA-392054", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10047453", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10045509": { "compartment": "compartment_876", "id": "reaction_10045509", "reactome": "R-BTA-376122", "name": "DSCAM/DSCAML1 homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045505" ], "products": [ "species_10045507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082055", "A0A3Q1MBH9", "ENSBTAT00000082055" ] }, "reaction_10045224": { "compartment": "compartment_70101", "id": "reaction_10045224", "reactome": "R-BTA-373738", "name": "Neurofascin interacts with syntenin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10045216" ], "products": [ "species_10045222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "ENSBTAT00000069125", "A0A3Q1LMZ3", "ENSBTAT00000069125", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069192": { "compartment": "compartment_70101", "id": "reaction_10069192", "reactome": "R-BTA-3928615", "name": "EFNBs bind SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069057", "species_10069161" ], "products": [ "species_10069190" ], "modifiers": [], "additional_components": [ "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069226": { "compartment": "compartment_70101", "id": "reaction_10069226", "reactome": "R-BTA-3928640", "name": "PAKs phosphorylate MLC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049739" ], "products": [ "species_10049762", "species_29370" ], "modifiers": [ [ "species_10069218", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021328", "ENSBTAT00000021328", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438" ] }, "reaction_10069418": { "compartment": "compartment_70101", "id": "reaction_10069418", "reactome": "R-BTA-4093329", "name": "EFNBs bind SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10069057" ], "products": [ "species_10069416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069221": { "compartment": "compartment_70101", "id": "reaction_10069221", "reactome": "R-BTA-3928625", "name": "PAKs autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069208" ], "products": [ "species_10069218", "species_29370" ], "modifiers": [ [ "species_10069208", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10069188": { "compartment": "compartment_70101", "id": "reaction_10069188", "reactome": "R-BTA-3928614", "name": "EFNB:GRB4 binds GIT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069184", "species_10069179" ], "products": [ "species_10069186" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073530", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530" ] }, "reaction_10069223": { "compartment": "compartment_70101", "id": "reaction_10069223", "reactome": "R-BTA-3928639", "name": "p-EFNB binds GRB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045210", "species_10069177" ], "products": [ "species_10069179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542" ] }, "reaction_10069243": { "compartment": "compartment_876", "id": "reaction_10069243", "reactome": "R-BTA-3928646", "name": "EPHAs bind EFNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068993", "species_10069023" ], "products": [ "species_10069025" ], "modifiers": [], "additional_components": [ "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958" ] }, "reaction_10069131": { "compartment": "compartment_876", "id": "reaction_10069131", "reactome": "R-BTA-3928591", "name": "EPH:EFN tetramers oligomerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069127", "species_10069129" ], "products": [ "species_10069061" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069285": { "compartment": "compartment_876", "id": "reaction_10069285", "reactome": "R-BTA-3928656", "name": "gamma-secretase cleaves EPHB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069263" ], "products": [ "species_10069283", "species_10069273" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10069157": { "compartment": "compartment_876", "id": "reaction_10069157", "reactome": "R-BTA-3928604", "name": "SFKs phosphorylate VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069152" ], "products": [ "species_10069154", "species_29370" ], "modifiers": [ [ "species_10069152", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069159": { "compartment": "compartment_876", "id": "reaction_10069159", "reactome": "R-BTA-3928607", "name": "p-EPHs bind VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069150", "species_10048073" ], "products": [ "species_10069152" ], "modifiers": [], "additional_components": [ "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "ENSBTAT00000086853", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069194": { "compartment": "compartment_876", "id": "reaction_10069194", "reactome": "R-BTA-3928624", "name": "EPHBs bind EFNBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069055", "species_10069037" ], "products": [ "species_10069057" ], "modifiers": [], "additional_components": [ "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069146": { "compartment": "compartment_876", "id": "reaction_10069146", "reactome": "R-BTA-3928597", "name": "EPH:EFN dimers tetramerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069129" ], "products": [ "species_10069127" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069121": { "compartment": "compartment_70101", "id": "reaction_10069121", "reactome": "R-BTA-3928578", "name": "EPH receptors autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069061", "species_113592" ], "products": [ "species_29370", "species_10069118" ], "modifiers": [ [ "species_10069061", "catalyst" ] ], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069144": { "compartment": "compartment_70101", "id": "reaction_10069144", "reactome": "R-BTA-3928592", "name": "p190RhoGEF exchanges GTP for GDP on RHOA, activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069141", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10069435": { "compartment": "compartment_876", "id": "reaction_10069435", "reactome": "R-BTA-4093339", "name": "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069428", "species_29356" ], "products": [ "species_29372", "species_10069432" ], "modifiers": [ [ "species_10069428", "catalyst" ] ], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29420", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10069148": { "compartment": "compartment_70101", "id": "reaction_10069148", "reactome": "R-BTA-3928598", "name": "Recruitment of p190RhoGEF to p-FAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069139", "species_10069135" ], "products": [ "species_10069141" ], "modifiers": [], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000074225", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10091007": { "compartment": "compartment_12045", "id": "reaction_10091007", "reactome": "R-BTA-9614271", "name": "Autocleavage of ADGRG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090998" ], "products": [ "species_10091004" ], "modifiers": [ [ "species_10090998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895", "ENSBTAT00000079895" ] }, "reaction_10091009": { "compartment": "compartment_876", "id": "reaction_10091009", "reactome": "R-BTA-9614273", "name": "ADGRG heterodimer translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091004" ], "products": [ "species_10091004" ], "modifiers": [], "additional_components": [ "A0A3Q1MTZ4", "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895" ] }, "reaction_10074603": { "compartment": "compartment_876", "id": "reaction_10074603", "reactome": "R-BTA-5682709", "name": "LGI4 binds ADAM22,23,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074599", "species_10074595" ], "products": [ "species_10074601" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025189", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A6QLD0", "ENSBTAT00000025189" ] }, "reaction_10074641": { "compartment": "compartment_984", "id": "reaction_10074641", "reactome": "R-BTA-5682802", "name": "LGI3 binds ADAM22,23,synatxin1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074637" ], "products": [ "species_10074639" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000006011", "E1BFY8", "ENSBTAT00000006011", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10074613": { "compartment": "compartment_984", "id": "reaction_10074613", "reactome": "R-BTA-5682769", "name": "LGI2 binds ADAM22,23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074607" ], "products": [ "species_10074611" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000023124", "F1MZT1", "ENSBTAT00000023124", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10081915": { "compartment": "compartment_70101", "id": "reaction_10081915", "reactome": "R-BTA-6806610", "name": "Keratin filament formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081911" ], "products": [ "species_10081913" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081917": { "compartment": "compartment_70101", "id": "reaction_10081917", "reactome": "R-BTA-6806613", "name": "Keratin tetramers bind to form unit length filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081859" ], "products": [ "species_10081909" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081857": { "compartment": "compartment_70101", "id": "reaction_10081857", "reactome": "R-BTA-6805546", "name": "Keratin type I binds keratin type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081853", "species_10081739" ], "products": [ "species_10081855" ], "modifiers": [], "additional_components": [ "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081921": { "compartment": "compartment_70101", "id": "reaction_10081921", "reactome": "R-BTA-6806629", "name": "Formation of tonofilament bundles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081913" ], "products": [ "species_10081919" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081861": { "compartment": "compartment_70101", "id": "reaction_10081861", "reactome": "R-BTA-6805573", "name": "Keratin type I/type II heterodimers form tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081855" ], "products": [ "species_10081859" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10082871": { "compartment": "compartment_70101", "id": "reaction_10082871", "reactome": "R-BTA-6809663", "name": "Formation of hair keratin fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082865", "species_10081919" ], "products": [ "species_10082869" ], "modifiers": [], "additional_components": [ "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298" ] }, "reaction_10050085": { "compartment": "compartment_7660", "id": "reaction_10050085", "reactome": "R-BTA-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050064", "species_10050074" ], "products": [ "species_113582", "species_10050082" ], "modifiers": [ [ "species_10050074", "catalyst" ] ], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050116": { "compartment": "compartment_7660", "id": "reaction_10050116", "reactome": "R-BTA-448963", "name": "Interaction of MyoD:E protein with MEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050080", "species_10050112" ], "products": [ "species_10050114" ], "modifiers": [], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "A0A3Q1NNL3", "ENSBTAT00000079928" ] }, "reaction_10044090": { "compartment": "compartment_7660", "id": "reaction_10044090", "reactome": "R-BTA-211178", "name": "Phosphorylated FOXO1A is excluded from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042680" ], "products": [ "species_10044088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127" ] }, "reaction_10071769": { "compartment": "compartment_7660", "id": "reaction_10071769", "reactome": "R-BTA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071589", "species_10071585" ], "products": [ "species_10071591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082240", "ENSBTAT00000022288", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071640": { "compartment": "compartment_7660", "id": "reaction_10071640", "reactome": "R-BTA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10071626" ], "products": [ "species_113582", "species_10071603" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592" ] }, "reaction_10071628": { "compartment": "compartment_7660", "id": "reaction_10071628", "reactome": "R-BTA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10071624" ], "products": [ "species_10071626" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071630": { "compartment": "compartment_7660", "id": "reaction_10071630", "reactome": "R-BTA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10071767": { "compartment": "compartment_7660", "id": "reaction_10071767", "reactome": "R-BTA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071599", "species_10071595" ], "products": [ "species_10071624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001867", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071607": { "compartment": "compartment_7660", "id": "reaction_10071607", "reactome": "R-BTA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071591", "species_10039892", "species_10071603" ], "products": [ "species_10071605" ], "modifiers": [], "additional_components": [ "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3ZBW4", "ENSBTAT00000007967", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071622": { "compartment": "compartment_7660", "id": "reaction_10071622", "reactome": "R-BTA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071605" ], "products": [ "species_10071619" ], "modifiers": [ [ "species_10071605", "catalyst" ] ], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071638": { "compartment": "compartment_7660", "id": "reaction_10071638", "reactome": "R-BTA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071634", "species_10071619" ], "products": [ "species_10071636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012365", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "E1BF15", "ENSBTAT00000012365", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071617": { "compartment": "compartment_7660", "id": "reaction_10071617", "reactome": "R-BTA-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10071613" ], "products": [ "species_10071615" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10071765": { "compartment": "compartment_7660", "id": "reaction_10071765", "reactome": "R-BTA-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071611", "species_10071595" ], "products": [ "species_10071613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076740", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10047196": { "compartment": "compartment_70101", "id": "reaction_10047196", "reactome": "R-BTA-390595", "name": "Calcium Binds Troponin-C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10047192" ], "products": [ "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047198": { "compartment": "compartment_70101", "id": "reaction_10047198", "reactome": "R-BTA-390597", "name": "Release Of ADP From Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047181" ], "products": [ "species_29370", "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047200": { "compartment": "compartment_70101", "id": "reaction_10047200", "reactome": "R-BTA-390598", "name": "Myosin Binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047194" ], "products": [ "species_10047177" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10047186": { "compartment": "compartment_70101", "id": "reaction_10047186", "reactome": "R-BTA-390593", "name": "ATP Hydrolysis By Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047177" ], "products": [ "species_29372", "species_10047181" ], "modifiers": [ [ "species_10047183", "catalyst" ] ], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10071824": { "compartment": "compartment_70101", "id": "reaction_10071824", "reactome": "R-BTA-5577237", "name": "KCNH2:KCNE transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071821", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1LSF6", "ENSBTAT00000067149" ] }, "reaction_10077468": { "compartment": "compartment_984", "id": "reaction_10077468", "reactome": "R-BTA-6784598", "name": "NPPA(124-151) binds NPR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071836", "species_10077464" ], "products": [ "species_10077466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008819", "E1BN71", "ENSBTAT00000008184", "E1BN71", "ENSBTAT00000008184", "P07501", "ENSBTAT00000008819" ] }, "reaction_10071843": { "compartment": "compartment_876", "id": "reaction_10071843", "reactome": "R-BTA-5578783", "name": "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071828" ], "products": [ "species_10071830", "species_10071836", "species_10071834", "species_10071832" ], "modifiers": [ [ "species_10071840", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000085692" ] }, "reaction_10071819": { "compartment": "compartment_876", "id": "reaction_10071819", "reactome": "R-BTA-5577234", "name": "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071816", "catalyst" ] ], "additional_components": [ "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "A0A3Q1LV43", "ENSBTAT00000072593", "A0A3Q1M5I5", "ENSBTAT00000066696" ] }, "reaction_10053180": { "compartment": "compartment_876", "id": "reaction_10053180", "reactome": "R-BTA-936897", "name": "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_113592", "species_83910" ], "products": [ "species_29372", "species_29804", "species_29370", "species_74113" ], "modifiers": [ [ "species_10053175", "catalyst" ], [ "species_10053178", "inhibitor" ] ], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10091759": { "compartment": "compartment_984", "id": "reaction_10091759", "reactome": "R-BTA-9684068", "name": "ATP1A:ATP1B:FXYD binds cardiac glycosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053175", "species_9684063" ], "products": [ "species_10053178" ], "modifiers": [], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10048787": { "compartment": "compartment_12045", "id": "reaction_10048787", "reactome": "R-BTA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10048770", "catalyst" ], [ "species_10048785", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10047893": { "compartment": "compartment_876", "id": "reaction_10047893", "reactome": "R-BTA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10047890", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077323" ] }, "reaction_10071876": { "compartment": "compartment_70101", "id": "reaction_10071876", "reactome": "R-BTA-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071873", "catalyst" ] ], "additional_components": [ "E1BEH3", "ENSBTAT00000004382", "A0A3Q1MT89", "ENSBTAT00000075452", "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182" ] }, "reaction_10035579": { "compartment": "compartment_12045", "id": "reaction_10035579", "reactome": "R-BTA-74872", "name": "RDH10,11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_10035564" ], "products": [ "species_70106", "species_10035566", "species_29364" ], "modifiers": [ [ "species_10035576", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q8HZT6", "ENSBTAT00000026830", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10065597": { "compartment": "compartment_12045", "id": "reaction_10065597", "reactome": "R-BTA-2454081", "name": "RDH5 oxidises 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_29360" ], "products": [ "species_70106", "species_10035566", "species_73473" ], "modifiers": [ [ "species_10065594", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q27979", "ENSBTAT00000065932" ] }, "reaction_10065644": { "compartment": "compartment_70101", "id": "reaction_10065644", "reactome": "R-BTA-2454264", "name": "11cROL binds to RLBP1 to form RLBP1:11cROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_10035562" ], "products": [ "species_10035564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_2473611" ] }, "reaction_10035406": { "compartment": "compartment_2514888", "id": "reaction_10035406", "reactome": "R-BTA-74101", "name": "Photons induce isomerization of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10035401" ], "products": [ "species_10035404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10065646": { "compartment": "compartment_70101", "id": "reaction_10065646", "reactome": "R-BTA-2464809", "name": "RBP3 regulates the transport of atROL from ROS to RPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473615" ], "products": [ "species_2473604" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10088914": { "compartment": "compartment_70101", "id": "reaction_10088914", "reactome": "R-BTA-8960973", "name": "RLBP1:11cRAL dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035566" ], "products": [ "species_8960974", "species_10035562" ], "modifiers": [], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_32737", "ENSBTAT00000047900" ] }, "reaction_10065604": { "compartment": "compartment_70101", "id": "reaction_10065604", "reactome": "R-BTA-2454113", "name": "RBP3 transports 11cRAL to rod photoreceptor outer segment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8960974" ], "products": [ "species_32737" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10077751": { "compartment": "compartment_12045", "id": "reaction_10077751", "reactome": "R-BTA-6786239", "name": "CYP4V2 omega-hydroxylates DHA to HDoHE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6786220", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6786225" ], "modifiers": [ [ "species_10077748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085962" ] }, "reaction_10035558": { "compartment": "compartment_70101", "id": "reaction_10035558", "reactome": "R-BTA-74843", "name": "atROL binds RBP1 to form RBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473604" ], "products": [ "species_10035556" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065606": { "compartment": "compartment_70101", "id": "reaction_10065606", "reactome": "R-BTA-2454118", "name": "11cRAL binds to opsin to form 11c-retinyl:RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2565923", "species_32737" ], "products": [ "species_29356", "species_10035401" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10049433": { "compartment": "compartment_876", "id": "reaction_10049433", "reactome": "R-BTA-442317", "name": "ZIP6 and ZIP14 mediate zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065246" ] }, "reaction_10049464": { "compartment": "compartment_876", "id": "reaction_10049464", "reactome": "R-BTA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049461", "catalyst" ] ], "additional_components": [ "Q3SYU3", "ENSBTAT00000034015", "E1BEU4", "ENSBTAT00000001238", "A0A3Q1LWM2", "ENSBTAT00000075196" ] }, "reaction_10049440": { "compartment": "compartment_876", "id": "reaction_10049440", "reactome": "R-BTA-442387", "name": "ZIP8 mediates zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049437", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007448" ] }, "reaction_10049447": { "compartment": "compartment_12045", "id": "reaction_10049447", "reactome": "R-BTA-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049444", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010771" ] }, "reaction_10071469": { "compartment": "compartment_70101", "id": "reaction_10071469", "reactome": "R-BTA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10071466", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006554" ] }, "reaction_10070735": { "compartment": "compartment_70101", "id": "reaction_10070735", "reactome": "R-BTA-5226964", "name": "ANKH transports PPi from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294" ], "products": [ "species_113542" ], "modifiers": [ [ "species_10070732", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017818" ] }, "reaction_10071280": { "compartment": "compartment_984", "id": "reaction_10071280", "reactome": "R-BTA-5252072", "name": "AZGP1 binds PIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071266", "species_10071276" ], "products": [ "species_10071278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037204", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "A0A452DK44", "ENSBTAT00000037204" ] }, "reaction_10071490": { "compartment": "compartment_70101", "id": "reaction_10071490", "reactome": "R-BTA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071487", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065645" ] }, "reaction_10087365": { "compartment": "compartment_70101", "id": "reaction_10087365", "reactome": "R-BTA-8941543", "name": "VRAC heteromer transports I-, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941540" ], "products": [ "species_8941541" ], "modifiers": [ [ "species_10087362", "catalyst" ] ], "additional_components": [ "species_352022", "species_209785", "species_209785", "species_352022", "A4IFE5", "ENSBTAT00000027912", "Q08E42", "ENSBTAT00000084512", "F6PRJ0", "ENSBTAT00000005636", "A5PK13", "ENSBTAT00000085971" ] }, "reaction_10071476": { "compartment": "compartment_70101", "id": "reaction_10071476", "reactome": "R-BTA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071473", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012110" ] }, "reaction_10086343": { "compartment": "compartment_70101", "id": "reaction_10086343", "reactome": "R-BTA-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10086340", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:32551", "species_113530", "species_113530", "species_29612", "CHEBI:32551", "ENSBTAT00000018143" ] }, "reaction_10071462": { "compartment": "compartment_70101", "id": "reaction_10071462", "reactome": "R-BTA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071459", "catalyst" ] ], "additional_components": [ "F1N136", "ENSBTAT00000002985" ] }, "reaction_10047930": { "compartment": "compartment_70101", "id": "reaction_10047930", "reactome": "R-BTA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10047927", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N569", "ENSBTAT00000072103" ] }, "reaction_10065369": { "compartment": "compartment_70101", "id": "reaction_10065369", "reactome": "R-BTA-2395869", "name": "NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065371": { "compartment": "compartment_70101", "id": "reaction_10065371", "reactome": "R-BTA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065386": { "compartment": "compartment_70101", "id": "reaction_10065386", "reactome": "R-BTA-2395965", "name": "NUDT18 hydrolyses 8-OH-dADP to 8-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395963", "species_29356" ], "products": [ "species_29372", "species_2395964" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065359": { "compartment": "compartment_70101", "id": "reaction_10065359", "reactome": "R-BTA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065760": { "compartment": "compartment_7660", "id": "reaction_10065760", "reactome": "R-BTA-2509793", "name": "NUDT16 hydrolyses dIDP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509796" ], "products": [ "species_113550", "species_2509805" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065328": { "compartment": "compartment_5460", "id": "reaction_10065328", "reactome": "R-BTA-2393954", "name": "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2393945", "species_113521" ], "products": [ "species_2393950", "species_159448" ], "modifiers": [ [ "species_10065325", "catalyst" ] ], "additional_components": [ "A7MBI8", "ENSBTAT00000015090", "species_29926" ] }, "reaction_10065763": { "compartment": "compartment_7660", "id": "reaction_10065763", "reactome": "R-BTA-2509816", "name": "NUDT16 hydrolyses IDP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509811" ], "products": [ "species_113550", "species_2509792" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065362": { "compartment": "compartment_70101", "id": "reaction_10065362", "reactome": "R-BTA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065378": { "compartment": "compartment_70101", "id": "reaction_10065378", "reactome": "R-BTA-2395873", "name": "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395880" ], "products": [ "species_29372", "species_2395877" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065381": { "compartment": "compartment_70101", "id": "reaction_10065381", "reactome": "R-BTA-2395876", "name": "NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065383": { "compartment": "compartment_70101", "id": "reaction_10065383", "reactome": "R-BTA-2395879", "name": "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065319": { "compartment": "compartment_70101", "id": "reaction_10065319", "reactome": "R-BTA-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10065316", "catalyst" ] ], "additional_components": [ "species_29926", "F1MMR8", "ENSBTAT00000068724" ] }, "reaction_10072489": { "compartment": "compartment_70101", "id": "reaction_10072489", "reactome": "R-BTA-5624131", "name": "UNC119B binds myristoylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072485", "species_10072480" ], "products": [ "species_10072487" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007584", "ENSBTAT00000009843", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10072497": { "compartment": "compartment_18730", "id": "reaction_10072497", "reactome": "R-BTA-5624132", "name": "UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072487" ], "products": [ "species_10072495" ], "modifiers": [], "additional_components": [ "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10033379": { "compartment": "compartment_7660", "id": "reaction_10033379", "reactome": "R-BTA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10033367" ], "modifiers": [ [ "species_10033377", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083861", "E1BG94", "ENSBTAT00000005182", "E1BD75", "ENSBTAT00000023554" ] }, "reaction_10033412": { "compartment": "compartment_70101", "id": "reaction_10033412", "reactome": "R-BTA-68712", "name": "The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10033390" ], "products": [ "species_10033410", "species_10033388" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336", "Q56JZ0", "ENSBTAT00000023040", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000067336" ] }, "reaction_10085788": { "compartment": "compartment_70101", "id": "reaction_10085788", "reactome": "R-BTA-8873794", "name": "PCTP binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075605", "species_1524163" ], "products": [ "species_10085786" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024898", "species_429785", "P02720", "ENSBTAT00000024898" ] }, "reaction_10086064": { "compartment": "compartment_12045", "id": "reaction_10086064", "reactome": "R-BTA-8877153", "name": "STARD7 binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10086060" ], "products": [ "species_10086062" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071992", "A0A3Q1LZP9", "ENSBTAT00000071992", "species_429785" ] }, "reaction_10085808": { "compartment": "compartment_70101", "id": "reaction_10085808", "reactome": "R-BTA-8873923", "name": "STARD10 binds LPCAT1 and PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035781", "species_426925", "species_10085792" ], "products": [ "species_10085794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001250", "ENSBTAT00000071421", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10085024": { "compartment": "compartment_984", "id": "reaction_10085024", "reactome": "R-BTA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10085021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017353" ] }, "reaction_10059141": { "compartment": "compartment_12045", "id": "reaction_10059141", "reactome": "R-BTA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10059138", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "species_29926", "A0A3Q1LV95", "ENSBTAT00000067199", "E1BLQ9", "ENSBTAT00000012081" ] }, "reaction_10059063": { "compartment": "compartment_70101", "id": "reaction_10059063", "reactome": "R-BTA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10059060", "catalyst" ] ], "additional_components": [ "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10085798": { "compartment": "compartment_70101", "id": "reaction_10085798", "reactome": "R-BTA-8873834", "name": "STARD10 transports PC from ER membrane to lamellar body membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085794" ], "products": [ "species_10085796", "species_10035781" ], "modifiers": [], "additional_components": [ "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "ENSBTAT00000001250" ] }, "reaction_10059094": { "compartment": "compartment_70101", "id": "reaction_10059094", "reactome": "R-BTA-1483159", "name": "PCho is dephosphorylated to Cho by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524071" ], "products": [ "species_264618", "species_29372" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10090489": { "compartment": "compartment_70101", "id": "reaction_10090489", "reactome": "R-BTA-9026780", "name": "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10090480": { "compartment": "compartment_70101", "id": "reaction_10090480", "reactome": "R-BTA-9026777", "name": "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10039964", "catalyst" ] ], "additional_components": [ "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425" ] }, "reaction_10090491": { "compartment": "compartment_70101", "id": "reaction_10090491", "reactome": "R-BTA-9026911", "name": "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024768" ], "products": [ "species_9026915" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10044835": { "compartment": "compartment_70101", "id": "reaction_10044835", "reactome": "R-BTA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10044837": { "compartment": "compartment_70101", "id": "reaction_10044837", "reactome": "R-BTA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10076360": { "compartment": "compartment_876", "id": "reaction_10076360", "reactome": "R-BTA-5693681", "name": "DUOX1,2 reduce O2 to H2O2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352327" ], "products": [ "species_351628", "species_351629" ], "modifiers": [ [ "species_10076357", "catalyst" ] ], "additional_components": [ "E1BMK1", "ENSBTAT00000021618", "E1BMS3", "ENSBTAT00000021603" ] }, "reaction_10043978": { "compartment": "compartment_876", "id": "reaction_10043978", "reactome": "R-BTA-209910", "name": "Iodide is taken up by thyroid epithelial cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10044828": { "compartment": "compartment_984", "id": "reaction_10044828", "reactome": "R-BTA-350901", "name": "Iodide is organified", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_209818", "species_351629" ], "products": [ "species_109276", "species_351630", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043980": { "compartment": "compartment_984", "id": "reaction_10043980", "reactome": "R-BTA-209925", "name": "DIT and MIT combine to form triiodothyronine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329", "species_351639" ], "products": [ "species_352331", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10043986": { "compartment": "compartment_984", "id": "reaction_10043986", "reactome": "R-BTA-209973", "name": "Tyrosine is diiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352030", "species_209818", "species_351629" ], "products": [ "species_109276", "species_352329", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043924": { "compartment": "compartment_984", "id": "reaction_10043924", "reactome": "R-BTA-209815", "name": "Tyrosine is monoiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351630", "species_352030" ], "products": [ "species_622410", "species_351639" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043956": { "compartment": "compartment_984", "id": "reaction_10043956", "reactome": "R-BTA-209840", "name": "Two DITs combine to form thyroxine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329" ], "products": [ "species_352326", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10066745": { "compartment": "compartment_7660", "id": "reaction_10066745", "reactome": "R-BTA-3222128", "name": "NOC2L binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066741" ], "products": [ "species_10066743" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021980", "Q3SYU1", "ENSBTAT00000021980", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066712": { "compartment": "compartment_7660", "id": "reaction_10066712", "reactome": "R-BTA-3222020", "name": "NUAK1 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066701" ], "products": [ "species_113582", "species_10066709", "species_10066690", "species_10066699" ], "modifiers": [ [ "species_10066701", "catalyst" ] ], "additional_components": [ "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081563": { "compartment": "compartment_7660", "id": "reaction_10081563", "reactome": "R-BTA-6805035", "name": "TP53 binds STK11 and NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066694", "species_10066677", "species_10066690" ], "products": [ "species_10066696" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013805", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10081595": { "compartment": "compartment_7660", "id": "reaction_10081595", "reactome": "R-BTA-6805276", "name": "CDK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10081585" ], "modifiers": [ [ "species_10081592", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064" ] }, "reaction_10080730": { "compartment": "compartment_7660", "id": "reaction_10080730", "reactome": "R-BTA-6799431", "name": "TP53 binds HIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080726", "species_10066677" ], "products": [ "species_10080728" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015051", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BQ34", "ENSBTAT00000015051" ] }, "reaction_10081629": { "compartment": "compartment_7660", "id": "reaction_10081629", "reactome": "R-BTA-6805479", "name": "TP53RK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081626", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000039179" ] }, "reaction_10066704": { "compartment": "compartment_7660", "id": "reaction_10066704", "reactome": "R-BTA-3222006", "name": "STK11 (LKB1) phosphorylates NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066696" ], "products": [ "species_113582", "species_10066701" ], "modifiers": [ [ "species_10066696", "catalyst" ] ], "additional_components": [ "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10080722": { "compartment": "compartment_7660", "id": "reaction_10080722", "reactome": "R-BTA-6799409", "name": "HIPK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066668" ], "products": [ "species_113582", "species_10066659", "species_10066666", "species_10078728" ], "modifiers": [ [ "species_10066668", "catalyst" ] ], "additional_components": [ "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "P67939", "ENSBTAT00000001420", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066870": { "compartment": "compartment_7660", "id": "reaction_10066870", "reactome": "R-BTA-3239014", "name": "MAPKAPK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10066862" ], "modifiers": [ [ "species_10066867", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10081622": { "compartment": "compartment_7660", "id": "reaction_10081622", "reactome": "R-BTA-6805470", "name": "AMPK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081619", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10078731": { "compartment": "compartment_7660", "id": "reaction_10078731", "reactome": "R-BTA-6798374", "name": "DYRK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033524" ], "products": [ "species_113582", "species_10078728" ], "modifiers": [ [ "species_10078718", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000009545" ] }, "reaction_10066670": { "compartment": "compartment_7660", "id": "reaction_10066670", "reactome": "R-BTA-3215251", "name": "TP53INP1 and HIPK2 bind TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066659", "species_10066666" ], "products": [ "species_10066668" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078720": { "compartment": "compartment_7660", "id": "reaction_10078720", "reactome": "R-BTA-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10078714" ], "products": [ "species_113582", "species_10078718" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009545", "ENSBTAT00000009545", "ENSBTAT00000040104" ] }, "reaction_10081602": { "compartment": "compartment_7660", "id": "reaction_10081602", "reactome": "R-BTA-6805285", "name": "PLK3 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10081599", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000008055" ] }, "reaction_10039801": { "compartment": "compartment_7660", "id": "reaction_10039801", "reactome": "R-BTA-174097", "name": "Association of Emi1 with Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039797" ], "products": [ "species_10039799" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "Q32L05", "ENSBTAT00000074490", "Q32L05", "ENSBTAT00000074490", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10039852": { "compartment": "compartment_7660", "id": "reaction_10039852", "reactome": "R-BTA-174235", "name": "Association of Emi1 with Cdc20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039803" ], "products": [ "species_10039850" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "ENSBTAT00000077512", "F1MRW5", "ENSBTAT00000077512", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10038033": { "compartment": "compartment_70101", "id": "reaction_10038033", "reactome": "R-BTA-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038027" ], "products": [ "species_10038031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10038035": { "compartment": "compartment_70101", "id": "reaction_10038035", "reactome": "R-BTA-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038019", "species_10038015", "species_10038027" ], "products": [ "species_10038029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000057027", "ENSBTAT00000009521", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MWP1", "ENSBTAT00000009521", "Q1JQB2", "ENSBTAT00000057027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10033833": { "compartment": "compartment_70101", "id": "reaction_10033833", "reactome": "R-BTA-70903", "name": "urocanate + H2O => 4-imidazolone-5-propionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30721" ], "products": [ "species_34979" ], "modifiers": [ [ "species_10033830", "catalyst" ] ], "additional_components": [ "species_29360", "A0A3Q1LXH7", "ENSBTAT00000083727" ] }, "reaction_10033849": { "compartment": "compartment_70101", "id": "reaction_10033849", "reactome": "R-BTA-70920", "name": "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30158", "species_111355" ], "products": [ "species_29404", "species_70919" ], "modifiers": [ [ "species_10033846", "catalyst" ] ], "additional_components": [ "A0A3Q1MBB6", "ENSBTAT00000074746" ] }, "reaction_10054585": { "compartment": "compartment_70101", "id": "reaction_10054585", "reactome": "R-BTA-977301", "name": "Histidine is decarboxylated to histamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612" ], "products": [ "species_175992", "species_113528" ], "modifiers": [ [ "species_10054582", "catalyst" ] ], "additional_components": [ "Q5EA83", "ENSBTAT00000013083" ] }, "reaction_10077758": { "compartment": "compartment_70101", "id": "reaction_10077758", "reactome": "R-BTA-6786245", "name": "CARNS1 transforms ATP, L-His, b-Ala to CARN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612", "species_113592", "species_73590" ], "products": [ "species_6786250", "species_29372", "species_29370" ], "modifiers": [ [ "species_10077755", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023529" ] }, "reaction_10086033": { "compartment": "compartment_70101", "id": "reaction_10086033", "reactome": "R-BTA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10086030", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010790" ] }, "reaction_10033840": { "compartment": "compartment_70101", "id": "reaction_10033840", "reactome": "R-BTA-70906", "name": "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34979" ], "products": [ "species_30158", "species_70106" ], "modifiers": [ [ "species_10033837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021647" ] }, "reaction_10059066": { "compartment": "compartment_70616", "id": "reaction_10059066", "reactome": "R-BTA-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524072", "species_1524067" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10092237": { "compartment": "compartment_7660", "id": "reaction_10092237", "reactome": "R-BTA-9707523", "name": "Hemes bind to BACH1:MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707575", "species_10092233" ], "products": [ "species_10055987", "species_10092235" ], "modifiers": [], "additional_components": [ "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092269": { "compartment": "compartment_70101", "id": "reaction_10092269", "reactome": "R-BTA-9708423", "name": "XPO1:BACH1:Hemes are transported out of the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092259" ], "products": [ "species_10092267" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092239": { "compartment": "compartment_7660", "id": "reaction_10092239", "reactome": "R-BTA-9707690", "name": "BACH1 binds MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231", "species_10055987" ], "products": [ "species_10092233" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092271": { "compartment": "compartment_7660", "id": "reaction_10092271", "reactome": "R-BTA-9708430", "name": "XPO1 (CRM1) binds to BACH1:Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092235", "species_10050265" ], "products": [ "species_10092259" ], "modifiers": [], "additional_components": [ "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092225": { "compartment": "compartment_984", "id": "reaction_10092225", "reactome": "R-BTA-9707505", "name": "Hemes bind to CLEC1B dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10092221" ], "products": [ "species_10092223" ], "modifiers": [], "additional_components": [ "species_71185", "E1BLL1", "ENSBTAT00000053034", "E1BLL1", "ENSBTAT00000053034", "species_71185" ] }, "reaction_10092227": { "compartment": "compartment_984", "id": "reaction_10092227", "reactome": "R-BTA-9707516", "name": "FeHM dissociates from MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743" ], "products": [ "species_917955", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10052914": { "compartment": "compartment_876", "id": "reaction_10052914", "reactome": "R-BTA-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "species_71185", "ENSBTAT00000035283" ] }, "reaction_10092214": { "compartment": "compartment_984", "id": "reaction_10092214", "reactome": "R-BTA-9707504", "name": "H2O2 oxidises ferrohemoglobin to MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_351629" ], "products": [ "species_10064743", "species_9707624", "species_9707647" ], "modifiers": [ [ "species_10092212", "inhibitor" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10081561": { "compartment": "compartment_7660", "id": "reaction_10081561", "reactome": "R-BTA-6804762", "name": "TP53 forms homotetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066422" ], "products": [ "species_10066677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10091685": { "compartment": "compartment_7660", "id": "reaction_10091685", "reactome": "R-BTA-9670114", "name": "Histone H3.3 deposition at telomere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091677", "species_10035227" ], "products": [ "species_10091683", "species_10040161" ], "modifiers": [], "additional_components": [ "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000034695", "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000033058" ] }, "reaction_10038540": { "compartment": "compartment_7660", "id": "reaction_10038540", "reactome": "R-BTA-163099", "name": "Alignment Of The RNA Template On The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038538" ], "products": [ "species_10038529" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10038947": { "compartment": "compartment_7660", "id": "reaction_10038947", "reactome": "R-BTA-164617", "name": "Elongation of Extended Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10038531", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10038542" ], "modifiers": [ [ "species_10038531", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038949": { "compartment": "compartment_7660", "id": "reaction_10038949", "reactome": "R-BTA-164620", "name": "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038531" ], "products": [ "species_10038531" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038534": { "compartment": "compartment_7660", "id": "reaction_10038534", "reactome": "R-BTA-163090", "name": "Elongation Of The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_30185", "species_10038529", "species_29892", "species_29604" ], "products": [ "species_10038531" ], "modifiers": [ [ "species_10038529", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10087577": { "compartment": "compartment_17957", "id": "reaction_10087577", "reactome": "R-BTA-8944242", "name": "Association of procollagen type XXVII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062035" ], "products": [ "species_10062840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081723", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10087579": { "compartment": "compartment_17957", "id": "reaction_10087579", "reactome": "R-BTA-8944246", "name": "Association of procollagen type XXI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062810" ], "products": [ "species_10062812" ], "modifiers": [], "additional_components": [ "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1MQC5", "ENSBTAT00000074238" ] }, "reaction_10087581": { "compartment": "compartment_17957", "id": "reaction_10087581", "reactome": "R-BTA-8944247", "name": "Association of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060135", "species_10060159", "species_10060111" ], "products": [ "species_10060183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025663", "ENSBTAT00000018479", "ENSBTAT00000015668", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087583": { "compartment": "compartment_17957", "id": "reaction_10087583", "reactome": "R-BTA-8944250", "name": "Association of procollagen type XXV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062400" ], "products": [ "species_10062823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087569": { "compartment": "compartment_17957", "id": "reaction_10087569", "reactome": "R-BTA-8944219", "name": "Association of procollagen type XVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062025" ], "products": [ "species_10062790" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065364", "G3MXK9", "ENSBTAT00000065364" ] }, "reaction_10087571": { "compartment": "compartment_17957", "id": "reaction_10087571", "reactome": "R-BTA-8944220", "name": "Association of procollagen type XXIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062031" ], "products": [ "species_10062821" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017548", "F1MSJ7", "ENSBTAT00000017548" ] }, "reaction_10087573": { "compartment": "compartment_17957", "id": "reaction_10087573", "reactome": "R-BTA-8944223", "name": "Association of procollagen type V", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062017", "species_10062045", "species_10062041" ], "products": [ "species_10062749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063052", "ENSBTAT00000013440", "ENSBTAT00000084344", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052" ] }, "reaction_10062071": { "compartment": "compartment_17957", "id": "reaction_10062071", "reactome": "R-BTA-2002401", "name": "Association of procollagen type XVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062037" ], "products": [ "species_10062069" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067622", "A0A3Q1LYA4", "ENSBTAT00000067622" ] }, "reaction_10087563": { "compartment": "compartment_17957", "id": "reaction_10087563", "reactome": "R-BTA-8944215", "name": "Association of procollagen type XX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062027" ], "products": [ "species_10062801" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063888", "G3N021", "ENSBTAT00000063888" ] }, "reaction_10087565": { "compartment": "compartment_17957", "id": "reaction_10087565", "reactome": "R-BTA-8944216", "name": "Association of procollagen type XV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062023" ], "products": [ "species_10062781" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10087567": { "compartment": "compartment_17957", "id": "reaction_10087567", "reactome": "R-BTA-8944218", "name": "Association of procollagen type VIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062019", "species_10062043" ], "products": [ "species_10062763" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018159", "ENSBTAT00000083731", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159" ] }, "reaction_10087585": { "compartment": "compartment_17957", "id": "reaction_10087585", "reactome": "R-BTA-8944254", "name": "Association of procollagen type XXVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062033" ], "products": [ "species_10062832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087587": { "compartment": "compartment_17957", "id": "reaction_10087587", "reactome": "R-BTA-8944261", "name": "Association of procollagen type XIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062021" ], "products": [ "species_10062772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10087589": { "compartment": "compartment_17957", "id": "reaction_10087589", "reactome": "R-BTA-8944263", "name": "Association of procollagen type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062015" ], "products": [ "species_10062709" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505" ] }, "reaction_10044446": { "compartment": "compartment_7660", "id": "reaction_10044446", "reactome": "R-BTA-212356", "name": "Formation of CSL-NICD coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10044434", "species_10044414", "species_10044442", "species_10044410", "species_10044424" ], "products": [ "species_10044444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "A0A3Q1MLT2", "ENSBTAT00000075969", "ENSBTAT00000050083", "ENSBTAT00000010697", "ENSBTAT00000004696", "A0A3Q1MF28", "ENSBTAT00000078064", "A0A3Q1MF28", "ENSBTAT00000078064", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "G3X812", "ENSBTAT00000050083", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10044726": { "compartment": "compartment_7660", "id": "reaction_10044726", "reactome": "R-BTA-350058", "name": "Formation of CSL NCOR corepressor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10044722", "species_10044704", "species_10044442", "species_10044410" ], "products": [ "species_10044724" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000010697", "ENSBTAT00000004696", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092287": { "compartment": "compartment_7660", "id": "reaction_10092287", "reactome": "R-BTA-9708517", "name": "FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10092281" ], "products": [ "species_10092277", "species_10092284", "species_10086712" ], "modifiers": [ [ "species_10092281", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000069043", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092273": { "compartment": "compartment_70101", "id": "reaction_10092273", "reactome": "R-BTA-9708466", "name": "BACH1 translocates from the nucleoplasm to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231" ], "products": [ "species_10092261" ], "modifiers": [ [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000005416" ] }, "reaction_10092289": { "compartment": "compartment_7660", "id": "reaction_10092289", "reactome": "R-BTA-9708525", "name": "BACH1:FBXL17 binds SCF(SKP2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092279", "species_10086712" ], "products": [ "species_10092281" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092293": { "compartment": "compartment_7660", "id": "reaction_10092293", "reactome": "R-BTA-9708557", "name": "FBXL17 binds BACH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092277", "species_10092233" ], "products": [ "species_10092279", "species_10055987" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069043", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702" ] }, "reaction_10057639": { "compartment": "compartment_876", "id": "reaction_10057639", "reactome": "R-BTA-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057636", "catalyst" ] ], "additional_components": [ "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182", "E1B9M4", "ENSBTAT00000014309" ] }, "reaction_10065673": { "compartment": "compartment_70101", "id": "reaction_10065673", "reactome": "R-BTA-2465919", "name": "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_200993" ], "products": [ "species_10065666", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "CHEBI:16254", "ENSBTAT00000074877" ] }, "reaction_10091560": { "compartment": "compartment_70101", "id": "reaction_10091560", "reactome": "R-BTA-9656893", "name": "OPN1MW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065675": { "compartment": "compartment_70101", "id": "reaction_10065675", "reactome": "R-BTA-2465924", "name": "OPN1LW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065677": { "compartment": "compartment_70101", "id": "reaction_10065677", "reactome": "R-BTA-2465934", "name": "11cROL translocates from Muller cells to cone photoreceptor cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473606" ], "products": [ "species_2473611" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065679": { "compartment": "compartment_70101", "id": "reaction_10065679", "reactome": "R-BTA-2465938", "name": "RBP3 regulates atROL taken up by Muller cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473607" ], "products": [ "species_2473617" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065664": { "compartment": "compartment_74000", "id": "reaction_10065664", "reactome": "R-BTA-2465917", "name": "Photons induce isomerisation of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065654", "species_419777" ], "products": [ "species_10065662" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10065683": { "compartment": "compartment_70101", "id": "reaction_10065683", "reactome": "R-BTA-2465971", "name": "RLBP1 binds atROL to form RLBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473617", "species_10035562" ], "products": [ "species_10065681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_975590" ] }, "reaction_10065687": { "compartment": "compartment_70101", "id": "reaction_10065687", "reactome": "R-BTA-2466085", "name": "at-retinyl is hydrolysed from R* to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10065662" ], "products": [ "species_10065685", "species_975622" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10091558": { "compartment": "compartment_70101", "id": "reaction_10091558", "reactome": "R-BTA-9656891", "name": "OPN1SW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048190", "species_32737" ], "products": [ "species_10065652", "species_29356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021912", "ENSBTAT00000021912" ] }, "reaction_10068899": { "compartment": "compartment_7660", "id": "reaction_10068899", "reactome": "R-BTA-3857336", "name": "CEBPB homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068891" ], "products": [ "species_10068893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086463", "A0A3Q1NLC4", "ENSBTAT00000086463" ] }, "reaction_10040355": { "compartment": "compartment_70101", "id": "reaction_10040355", "reactome": "R-BTA-182594", "name": "Association of INK4 family proteins with CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040351", "species_10040345" ], "products": [ "species_10040353" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10088026": { "compartment": "compartment_984", "id": "reaction_10088026", "reactome": "R-BTA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10088023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009888" ] }, "reaction_10058910": { "compartment": "compartment_12045", "id": "reaction_10058910", "reactome": "R-BTA-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524028" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058871": { "compartment": "compartment_12045", "id": "reaction_10058871", "reactome": "R-BTA-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975614" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10057007": { "compartment": "compartment_70101", "id": "reaction_10057007", "reactome": "R-BTA-1237042", "name": "AQP1 tetramer transports CO2 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237009" ], "products": [ "species_113528" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10081968": { "compartment": "compartment_70101", "id": "reaction_10081968", "reactome": "R-BTA-6806831", "name": "CYB5Rs reduce MetHb to HbA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081949", "species_73473" ], "products": [ "species_70106", "species_10081955", "species_29360" ], "modifiers": [ [ "species_10081965", "catalyst" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "A0A3Q1LIS5", "ENSBTAT00000068812", "A0A3Q1MXD6", "ENSBTAT00000072609" ] }, "reaction_10058790": { "compartment": "compartment_70101", "id": "reaction_10058790", "reactome": "R-BTA-1475435", "name": "CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057062": { "compartment": "compartment_70101", "id": "reaction_10057062", "reactome": "R-BTA-1237325", "name": "Hemoglobin A is protonated and carbamated causing release of oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057046", "species_70106", "species_113528" ], "products": [ "species_10057060", "species_29368" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10037739": { "compartment": "compartment_70101", "id": "reaction_10037739", "reactome": "R-BTA-140216", "name": "Translocation of PMAIP1 (NOXA) to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037735" ], "products": [ "species_10037737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071269", "ENSBTAT00000071269" ] }, "reaction_10058985": { "compartment": "compartment_70616", "id": "reaction_10058985", "reactome": "R-BTA-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524083", "species_1498773" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058955": { "compartment": "compartment_70616", "id": "reaction_10058955", "reactome": "R-BTA-1482781", "name": "MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524075", "species_1498773" ], "products": [ "species_1524072", "species_1524079" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058993": { "compartment": "compartment_12045", "id": "reaction_10058993", "reactome": "R-BTA-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1524069" ], "products": [ "species_1524081", "species_76194" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10058998": { "compartment": "compartment_12045", "id": "reaction_10058998", "reactome": "R-BTA-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10045466": { "compartment": "compartment_204883", "id": "reaction_10045466", "reactome": "R-BTA-375342", "name": "Connexin 36 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045463", "catalyst" ] ], "additional_components": [ "Q866T7", "ENSBTAT00000028966" ] }, "reaction_10045455": { "compartment": "compartment_876", "id": "reaction_10045455", "reactome": "R-BTA-375340", "name": "Connexin 62 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045452", "catalyst" ] ], "additional_components": [ "E1BLU3", "ENSBTAT00000015039" ] }, "reaction_10045444": { "compartment": "compartment_876", "id": "reaction_10045444", "reactome": "R-BTA-375339", "name": "Pannexin 1/Pannexin2 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045441", "catalyst" ] ], "additional_components": [ "D7R519", "ENSBTAT00000015932", "G5E5X7", "ENSBTAT00000037612" ] }, "reaction_10084238": { "compartment": "compartment_262783", "id": "reaction_10084238", "reactome": "R-BTA-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084234" ], "products": [ "species_10084236" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "G3N3N1", "ENSBTAT00000063023", "species_29438", "G3N3N1", "ENSBTAT00000063023", "species_29438", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084291": { "compartment": "compartment_5683628", "id": "reaction_10084291", "reactome": "R-BTA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084286" ], "products": [ "species_29372", "species_10084288" ], "modifiers": [ [ "species_10084286", "catalyst" ], [ "species_10084272", "catalyst" ] ], "additional_components": [ "E1BJA0", "ENSBTAT00000083670", "species_29438", "E1BJA0", "ENSBTAT00000083670", "species_29420", "E1BJA0", "ENSBTAT00000083670", "species_29438", "ENSBTAT00000012236" ] }, "reaction_10084261": { "compartment": "compartment_17938", "id": "reaction_10084261", "reactome": "R-BTA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084252" ], "products": [ "species_29372", "species_10084254" ], "modifiers": [ [ "species_10084252", "catalyst" ], [ "species_10084259", "catalyst" ] ], "additional_components": [ "species_29438", "Q08DE8", "ENSBTAT00000016976", "Q08DE8", "ENSBTAT00000016976", "species_29420", "species_29438", "Q08DE8", "ENSBTAT00000016976", "ENSBTAT00000082752" ] }, "reaction_10084228": { "compartment": "compartment_19363", "id": "reaction_10084228", "reactome": "R-BTA-8854209", "name": "TBC1D10A binds JFC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084220" ], "products": [ "species_10084226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "ENSBTAT00000077895", "A0A3Q1M443", "ENSBTAT00000077895", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084276": { "compartment": "compartment_5683628", "id": "reaction_10084276", "reactome": "R-BTA-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084272", "species_10084268" ], "products": [ "species_10084274" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012236", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "E1BHZ5", "ENSBTAT00000012236" ] }, "reaction_10084246": { "compartment": "compartment_20699", "id": "reaction_10084246", "reactome": "R-BTA-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084242", "species_10083720" ], "products": [ "species_10084244" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061025", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N746", "ENSBTAT00000061025" ] }, "reaction_10044801": { "compartment": "compartment_70101", "id": "reaction_10044801", "reactome": "R-BTA-350604", "name": "Agmatine + H2O <=> putrescine + urea", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_351164" ], "products": [ "species_29514", "species_29610" ], "modifiers": [ [ "species_10044798", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085149" ] }, "reaction_10041177": { "compartment": "compartment_70101", "id": "reaction_10041177", "reactome": "R-BTA-192051", "name": "CYP7A1 7-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192114" ], "modifiers": [ [ "species_10041174", "catalyst" ] ], "additional_components": [ "E1BM29", "ENSBTAT00000006957" ] }, "reaction_10041500": { "compartment": "compartment_70101", "id": "reaction_10041500", "reactome": "R-BTA-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194634", "species_29364" ], "products": [ "species_29356", "species_29366", "species_194644", "species_29460" ], "modifiers": [ [ "species_10041497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002582" ] }, "reaction_10041206": { "compartment": "compartment_5460", "id": "reaction_10041206", "reactome": "R-BTA-192123", "name": "CYP27A1 27-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193840", "species_113600" ], "products": [ "species_113563", "species_193846", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10044232": { "compartment": "compartment_70101", "id": "reaction_10044232", "reactome": "R-BTA-211951", "name": "CYP1B1 4-hydroxylates EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_211973" ], "modifiers": [ [ "species_10044229", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075887", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10041195": { "compartment": "compartment_70101", "id": "reaction_10041195", "reactome": "R-BTA-192065", "name": "CYP7B1 7-hydroxylates 25OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_192148", "species_29364" ], "products": [ "species_29356", "species_192184", "species_29366" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10043964": { "compartment": "compartment_70101", "id": "reaction_10043964", "reactome": "R-BTA-209845", "name": "CYP2R1 25-hydroxylates VD3 to 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_8963870", "species_29364" ], "products": [ "species_8963879", "species_29356", "species_29366" ], "modifiers": [ [ "species_10043961", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084891" ] }, "reaction_10044225": { "compartment": "compartment_5460", "id": "reaction_10044225", "reactome": "R-BTA-211950", "name": "CYP24A1 24-hydroxylates CTL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_215607", "species_113600" ], "products": [ "species_113563", "species_215622", "species_113521" ], "modifiers": [ [ "species_10043907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10043971": { "compartment": "compartment_70101", "id": "reaction_10043971", "reactome": "R-BTA-209868", "name": "CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209804", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_209800", "species_29366" ], "modifiers": [ [ "species_10043968", "catalyst" ], [ "species_29532", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022485" ] }, "reaction_10044293": { "compartment": "compartment_12045", "id": "reaction_10044293", "reactome": "R-BTA-212007", "name": "CYP26A1,B1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10044280": { "compartment": "compartment_12045", "id": "reaction_10044280", "reactome": "R-BTA-212005", "name": "CYP2F1 dehydrogenates 3-methylindole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_213162", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213163" ], "modifiers": [ [ "species_10044277", "catalyst" ] ], "additional_components": [ "G3MYW0", "ENSBTAT00000063781" ] }, "reaction_10044218": { "compartment": "compartment_12045", "id": "reaction_10044218", "reactome": "R-BTA-211929", "name": "CYP2C19 5-hydroxylates omeprazole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211892", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211944" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044250": { "compartment": "compartment_12045", "id": "reaction_10044250", "reactome": "R-BTA-211966", "name": "CYP2D6 4-hydroxylates debrisoquine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211993", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211952" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10044477": { "compartment": "compartment_12045", "id": "reaction_10044477", "reactome": "R-BTA-213175", "name": "CYP3A4,5 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_156522", "species_113601" ], "products": [ "species_113519", "species_113564", "species_156523" ], "modifiers": [ [ "species_10044474", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044223": { "compartment": "compartment_12045", "id": "reaction_10044223", "reactome": "R-BTA-211948", "name": "CYP3A4 can N-demethylate loperamide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_213155" ], "products": [ "species_113519", "species_113564", "species_213151" ], "modifiers": [ [ "species_10044220", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10035865": { "compartment": "compartment_17960", "id": "reaction_10035865", "reactome": "R-BTA-76426", "name": "N-atom dealkylation of caffeine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_40727", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76424" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10035861": { "compartment": "compartment_17960", "id": "reaction_10035861", "reactome": "R-BTA-76373", "name": "N-hydroxylation of 4-aminobiphenyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_47687", "species_113601" ], "products": [ "species_113519", "species_113564", "species_34889" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10044275": { "compartment": "compartment_12045", "id": "reaction_10044275", "reactome": "R-BTA-212004", "name": "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_211939" ], "products": [ "species_113519", "species_113564", "species_211927" ], "modifiers": [ [ "species_10044272", "catalyst" ] ], "additional_components": [ "F1MRH2", "ENSBTAT00000040300" ] }, "reaction_10044182": { "compartment": "compartment_12045", "id": "reaction_10044182", "reactome": "R-BTA-211882", "name": "CYP3A7 can 6beta-hydroxylate testosterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044179", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10035977": { "compartment": "compartment_12045", "id": "reaction_10035977", "reactome": "R-BTA-76472", "name": "Ethylene is oxidized to Ethylene oxide by CYP1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_38985", "species_113601" ], "products": [ "species_113519", "species_113564", "species_38987" ], "modifiers": [ [ "species_10035962", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061300", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10044265": { "compartment": "compartment_12045", "id": "reaction_10044265", "reactome": "R-BTA-211988", "name": "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211855", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211937" ], "modifiers": [ [ "species_10044262", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159" ] }, "reaction_10044204": { "compartment": "compartment_12045", "id": "reaction_10044204", "reactome": "R-BTA-211910", "name": "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211906", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211894" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044270": { "compartment": "compartment_12045", "id": "reaction_10044270", "reactome": "R-BTA-211991", "name": "Cyclophosphamide is 4-hydroxylated by CYP2B6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211977", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211967" ], "modifiers": [ [ "species_10044267", "catalyst" ] ], "additional_components": [ "A0A3Q1MU42", "ENSBTAT00000079854" ] }, "reaction_10044167": { "compartment": "compartment_12045", "id": "reaction_10044167", "reactome": "R-BTA-211881", "name": "Coumarin is 7-hydroxylated by CYP2A13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10044164", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10035911": { "compartment": "compartment_12045", "id": "reaction_10035911", "reactome": "R-BTA-76456", "name": "O-atom dealkylation of dextromethorphan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_39703", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76455" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10035878": { "compartment": "compartment_12045", "id": "reaction_10035878", "reactome": "R-BTA-76453", "name": "Coumarin is 7-hydroxylated by CYP2A6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10035875", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10059035": { "compartment": "compartment_12045", "id": "reaction_10059035", "reactome": "R-BTA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10059032", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "Q17QM4", "ENSBTAT00000010310" ] }, "reaction_10059082": { "compartment": "compartment_70101", "id": "reaction_10059082", "reactome": "R-BTA-1483096", "name": "PETA is dephosphorylated to ETA by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428686" ], "products": [ "species_29372", "species_1498751" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10059130": { "compartment": "compartment_12045", "id": "reaction_10059130", "reactome": "R-BTA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10059127", "catalyst" ] ], "additional_components": [ "A0A3Q1MLB5", "ENSBTAT00000070509" ] }, "reaction_10059150": { "compartment": "compartment_70101", "id": "reaction_10059150", "reactome": "R-BTA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10059147", "catalyst" ] ], "additional_components": [ "F1MRD9", "ENSBTAT00000024637", "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10076994": { "compartment": "compartment_5460", "id": "reaction_10076994", "reactome": "R-BTA-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696414", "species_113521" ], "products": [ "species_113548", "species_113532", "species_5693978" ], "modifiers": [ [ "species_10076991", "catalyst" ] ], "additional_components": [ "Q5E9S4", "ENSBTAT00000013587" ] }, "reaction_10077004": { "compartment": "compartment_12045", "id": "reaction_10077004", "reactome": "R-BTA-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10058892": { "compartment": "compartment_12045", "id": "reaction_10058892", "reactome": "R-BTA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10059006": { "compartment": "compartment_12045", "id": "reaction_10059006", "reactome": "R-BTA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10058894": { "compartment": "compartment_12045", "id": "reaction_10058894", "reactome": "R-BTA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058961": { "compartment": "compartment_12045", "id": "reaction_10058961", "reactome": "R-BTA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058819": { "compartment": "compartment_12045", "id": "reaction_10058819", "reactome": "R-BTA-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_1500593", "species_76116" ], "modifiers": [ [ "species_10058816", "catalyst" ] ], "additional_components": [ "A0A3Q1LUK0", "ENSBTAT00000073448" ] }, "reaction_10058948": { "compartment": "compartment_12045", "id": "reaction_10058948", "reactome": "R-BTA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10083572": { "compartment": "compartment_12045", "id": "reaction_10083572", "reactome": "R-BTA-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10083569", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010259" ] }, "reaction_10038938": { "compartment": "compartment_7660", "id": "reaction_10038938", "reactome": "R-BTA-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038932", "species_164121" ], "products": [ "species_10038936" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10083614": { "compartment": "compartment_984", "id": "reaction_10083614", "reactome": "R-BTA-8848663", "name": "ADIPOQ trimer binds ADIPOR dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083610", "species_10083594" ], "products": [ "species_10083612" ], "modifiers": [], "additional_components": [ "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795", "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795" ] }, "reaction_10060553": { "compartment": "compartment_172574", "id": "reaction_10060553", "reactome": "R-BTA-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060537": { "compartment": "compartment_172574", "id": "reaction_10060537", "reactome": "R-BTA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060468": { "compartment": "compartment_172574", "id": "reaction_10060468", "reactome": "R-BTA-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_29372", "species_1806195" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10088526": { "compartment": "compartment_5460", "id": "reaction_10088526", "reactome": "R-BTA-8952903", "name": "ADPRHL2 hydrolyses poly(ADP-ribose)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8952909", "species_113521" ], "products": [ "species_8952909", "species_8952905" ], "modifiers": [ [ "species_10088523", "catalyst" ] ], "additional_components": [ "species_8870342", "species_8870342", "ENSBTAT00000028950" ] }, "reaction_10037674": { "compartment": "compartment_70101", "id": "reaction_10037674", "reactome": "R-BTA-139899", "name": "Sequestration of BAD protein by 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10037644" ], "products": [ "species_10037672" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000016610", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10037678": { "compartment": "compartment_70101", "id": "reaction_10037678", "reactome": "R-BTA-139905", "name": "Translocation of activated BAD protein to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037676" ], "products": [ "species_10037626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "ENSBTAT00000016610" ] }, "reaction_10037630": { "compartment": "compartment_17906", "id": "reaction_10037630", "reactome": "R-BTA-139897", "name": "BAD displaces tBID from BCL-2 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037626", "species_10037275" ], "products": [ "species_10037269", "species_10037628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "F6R2C4", "ENSBTAT00000025701", "F1MUT9", "ENSBTAT00000016610" ] }, "reaction_10047900": { "compartment": "compartment_114521", "id": "reaction_10047900", "reactome": "R-BTA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10047897", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158" ] }, "reaction_10076824": { "compartment": "compartment_17906", "id": "reaction_10076824", "reactome": "R-BTA-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696066", "species_5696069" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10076821", "catalyst" ] ], "additional_components": [ "species_6814795", "species_6797635", "species_1524101", "species_417891", "A0A3Q1MFM9", "ENSBTAT00000074114", "species_29926" ] }, "reaction_10085340": { "compartment": "compartment_70101", "id": "reaction_10085340", "reactome": "R-BTA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10085337", "catalyst" ] ], "additional_components": [ "E1B9I9", "ENSBTAT00000013851", "A0A3Q1MUM3", "ENSBTAT00000079883", "A0A3Q1N293", "ENSBTAT00000069345" ] }, "reaction_10059091": { "compartment": "compartment_12045", "id": "reaction_10059091", "reactome": "R-BTA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10059088", "catalyst" ] ], "additional_components": [ "species_29926", "G3MZU2", "ENSBTAT00000065725" ] }, "reaction_10059044": { "compartment": "compartment_12045", "id": "reaction_10059044", "reactome": "R-BTA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10059041", "catalyst" ] ], "additional_components": [ "Q3T103", "ENSBTAT00000010454", "species_29926", "species_113527" ] }, "reaction_10071344": { "compartment": "compartment_876", "id": "reaction_10071344", "reactome": "R-BTA-5333678", "name": "CPNEs bind PL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071340", "species_171142" ], "products": [ "species_10071342" ], "modifiers": [ [ "species_74016", "catalyst" ] ], "additional_components": [ "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644", "species_171142", "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10059849": { "compartment": "compartment_984", "id": "reaction_10059849", "reactome": "R-BTA-1602374", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_33625" ], "products": [ "species_1602419", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058943": { "compartment": "compartment_12045", "id": "reaction_10058943", "reactome": "R-BTA-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10085310": { "compartment": "compartment_12045", "id": "reaction_10085310", "reactome": "R-BTA-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_392417", "species_1500646" ], "products": [ "species_33625", "species_1806234" ], "modifiers": [ [ "species_10085307", "catalyst" ] ], "additional_components": [ "A0A3Q1MI45", "ENSBTAT00000070851", "F1MFD9", "ENSBTAT00000012114", "A0A3Q1LWY5", "ENSBTAT00000073265" ] }, "reaction_10058945": { "compartment": "compartment_12045", "id": "reaction_10058945", "reactome": "R-BTA-1482776", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058880": { "compartment": "compartment_12045", "id": "reaction_10058880", "reactome": "R-BTA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10058916": { "compartment": "compartment_12045", "id": "reaction_10058916", "reactome": "R-BTA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10059014": { "compartment": "compartment_12045", "id": "reaction_10059014", "reactome": "R-BTA-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059016": { "compartment": "compartment_12045", "id": "reaction_10059016", "reactome": "R-BTA-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059018": { "compartment": "compartment_12045", "id": "reaction_10059018", "reactome": "R-BTA-1482907", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058826": { "compartment": "compartment_70616", "id": "reaction_10058826", "reactome": "R-BTA-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10059021": { "compartment": "compartment_12045", "id": "reaction_10059021", "reactome": "R-BTA-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058877": { "compartment": "compartment_12045", "id": "reaction_10058877", "reactome": "R-BTA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058812": { "compartment": "compartment_12045", "id": "reaction_10058812", "reactome": "R-BTA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058913": { "compartment": "compartment_70616", "id": "reaction_10058913", "reactome": "R-BTA-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10058983": { "compartment": "compartment_70616", "id": "reaction_10058983", "reactome": "R-BTA-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524047", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10059847": { "compartment": "compartment_984", "id": "reaction_10059847", "reactome": "R-BTA-1602368", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602402" ], "products": [ "species_1602415", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058934": { "compartment": "compartment_70616", "id": "reaction_10058934", "reactome": "R-BTA-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524027", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10058809": { "compartment": "compartment_12045", "id": "reaction_10058809", "reactome": "R-BTA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058970": { "compartment": "compartment_12045", "id": "reaction_10058970", "reactome": "R-BTA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10058829": { "compartment": "compartment_12045", "id": "reaction_10058829", "reactome": "R-BTA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058990": { "compartment": "compartment_12045", "id": "reaction_10058990", "reactome": "R-BTA-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058987", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059856": { "compartment": "compartment_984", "id": "reaction_10059856", "reactome": "R-BTA-1602399", "name": "PC is hydrolyzed to 1-acyl LPC by PLB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10059858": { "compartment": "compartment_984", "id": "reaction_10059858", "reactome": "R-BTA-1602417", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10085826": { "compartment": "compartment_12045", "id": "reaction_10085826", "reactome": "R-BTA-8874435", "name": "THEM86B hydrolyses PMCHO, PMETAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8874447" ], "products": [ "species_8874450", "species_5696116" ], "modifiers": [ [ "species_10085823", "catalyst" ] ], "additional_components": [ "CHEBI:17810", "CHEBI:17476", "CHEBI:36313", "CHEBI:36314", "ENSBTAT00000076823" ] }, "reaction_10058996": { "compartment": "compartment_12045", "id": "reaction_10058996", "reactome": "R-BTA-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524021", "species_975614" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059121": { "compartment": "compartment_12045", "id": "reaction_10059121", "reactome": "R-BTA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10059118", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018461" ] }, "reaction_10059073": { "compartment": "compartment_12045", "id": "reaction_10059073", "reactome": "R-BTA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10059070", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077015" ] }, "reaction_10059101": { "compartment": "compartment_70616", "id": "reaction_10059101", "reactome": "R-BTA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10059098", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007970" ] }, "reaction_10057390": { "compartment": "compartment_876", "id": "reaction_10057390", "reactome": "R-BTA-1296043", "name": "Activation of HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057387", "catalyst" ] ], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10057607": { "compartment": "compartment_876", "id": "reaction_10057607", "reactome": "R-BTA-1297444", "name": "Binding of cAMP to HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10057385" ], "products": [ "species_10057387" ], "modifiers": [], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10049326": { "compartment": "compartment_876", "id": "reaction_10049326", "reactome": "R-BTA-433104", "name": "NACT co-transports trivalent citrate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433138", "species_74113" ], "products": [ "species_76190", "species_83910" ], "modifiers": [ [ "species_10049323", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006144" ] }, "reaction_10049333": { "compartment": "compartment_876", "id": "reaction_10049333", "reactome": "R-BTA-433114", "name": "NaS1 co-transports sulphate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_74113" ], "products": [ "species_83910", "species_174375" ], "modifiers": [ [ "species_10049330", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078998" ] }, "reaction_10051305": { "compartment": "compartment_876", "id": "reaction_10051305", "reactome": "R-BTA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10051302", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "species_561052", "species_561052", "CHEBI:104011", "F1MIJ1", "ENSBTAT00000018132", "G3N1R8", "ENSBTAT00000064695", "F1MII8", "ENSBTAT00000018139" ] }, "reaction_10051314": { "compartment": "compartment_876", "id": "reaction_10051314", "reactome": "R-BTA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10051311", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068956" ] }, "reaction_10051307": { "compartment": "compartment_876", "id": "reaction_10051307", "reactome": "R-BTA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051325": { "compartment": "compartment_876", "id": "reaction_10051325", "reactome": "R-BTA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10051322", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016935" ] }, "reaction_10051276": { "compartment": "compartment_876", "id": "reaction_10051276", "reactome": "R-BTA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10051273", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013203" ] }, "reaction_10051283": { "compartment": "compartment_876", "id": "reaction_10051283", "reactome": "R-BTA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051269": { "compartment": "compartment_876", "id": "reaction_10051269", "reactome": "R-BTA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10051286": { "compartment": "compartment_876", "id": "reaction_10051286", "reactome": "R-BTA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10067993": { "compartment": "compartment_7660", "id": "reaction_10067993", "reactome": "R-BTA-3371537", "name": "DBC1 binds SIRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048710", "species_10067989" ], "products": [ "species_10067991" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018630", "ENSBTAT00000007194", "E1B9H3", "ENSBTAT00000007194", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10071241": { "compartment": "compartment_70101", "id": "reaction_10071241", "reactome": "R-BTA-5251959", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10071123" ], "products": [ "species_29372", "species_10071232" ], "modifiers": [ [ "species_10071238", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q27975", "ENSBTAT00000017500", "species_29370", "Q3MI00", "ENSBTAT00000036270", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437" ] }, "reaction_10068008": { "compartment": "compartment_7660", "id": "reaction_10068008", "reactome": "R-BTA-3371567", "name": "DBC1 is phosphorylated by ATM/ART", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10067995" ], "products": [ "species_113582", "species_10067989" ], "modifiers": [ [ "species_10068005", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007194", "ENSBTAT00000007194", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1M8V1", "ENSBTAT00000066572" ] }, "reaction_10071208": { "compartment": "compartment_7660", "id": "reaction_10071208", "reactome": "R-BTA-5251955", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10071171" ], "products": [ "species_113550", "species_10071169", "species_10071195" ], "modifiers": [ [ "species_10071205", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q56JY0", "ENSBTAT00000026632", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_29370", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437", "Q3MI00", "ENSBTAT00000036270" ] }, "reaction_10071313": { "compartment": "compartment_70101", "id": "reaction_10071313", "reactome": "R-BTA-5252079", "name": "HSP110s exchange ATP for ADP on HSP70s:ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071232", "species_113592" ], "products": [ "species_10071123", "species_29370" ], "modifiers": [ [ "species_10071304", "catalyst" ], [ "species_10071311", "inhibitor" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_29370", "Q27975", "ENSBTAT00000017500", "species_113592", "Q0IIM3", "ENSBTAT00000006600", "Q148J7", "ENSBTAT00000023720", "Q3ZBG5", "ENSBTAT00000007039", "F1MIU2", "ENSBTAT00000018131", "F1MSS9", "ENSBTAT00000017468", "A0A3Q1MQM3", "ENSBTAT00000074682" ] }, "reaction_10071127": { "compartment": "compartment_70101", "id": "reaction_10071127", "reactome": "R-BTA-5251942", "name": "Hikeshi binds HSP70s:ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071123", "species_10071069" ], "products": [ "species_10071125" ], "modifiers": [], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "ENSBTAT00000026632", "Q56JY0", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_113592" ] }, "reaction_10092312": { "compartment": "compartment_70616", "id": "reaction_10092312", "reactome": "R-BTA-9709406", "name": "CO binds to Cytochrome c oxidase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9709326", "species_10038606" ], "products": [ "species_10038645" ], "modifiers": [], "additional_components": [ "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10040636": { "compartment": "compartment_70101", "id": "reaction_10040636", "reactome": "R-BTA-189398", "name": "HMOX1 dimer, HMOX2 cleave heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364", "species_71185" ], "products": [ "species_29356", "species_189385", "species_71067", "species_189396", "species_29366" ], "modifiers": [ [ "species_10040633", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047056" ] }, "reaction_10047807": { "compartment": "compartment_7660", "id": "reaction_10047807", "reactome": "R-BTA-400143", "name": "Fatty acid ligands activate PPARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047799", "species_10047793", "species_10047777" ], "products": [ "species_10047797", "species_10047805", "species_10047771" ], "modifiers": [], "additional_components": [ "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "P80425", "ENSBTAT00000024032", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068", "B7TCI5", "ENSBTAT00000084466", "Q5EA13", "ENSBTAT00000068423", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000024032", "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "Q5EA13", "ENSBTAT00000068423", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092308": { "compartment": "compartment_984", "id": "reaction_10092308", "reactome": "R-BTA-9709317", "name": "CO binds to free ferrohemoglobin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_9709335" ], "products": [ "species_10092212" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10092310": { "compartment": "compartment_984", "id": "reaction_10092310", "reactome": "R-BTA-9709360", "name": "H2O2 reduces MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_351629" ], "products": [ "species_109276", "species_10092210", "species_352327" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10067416": { "compartment": "compartment_70101", "id": "reaction_10067416", "reactome": "R-BTA-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067409" ], "products": [ "species_10067413", "species_10067395" ], "modifiers": [ [ "species_10067409", "catalyst" ] ], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_29426", "species_3299744", "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10056408": { "compartment": "compartment_1222693", "id": "reaction_10056408", "reactome": "R-BTA-1222376", "name": "NOX2 generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_70106", "species_1222424", "species_29366" ], "modifiers": [ [ "species_10056405", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "species_71185", "O46521", "ENSBTAT00000067849", "species_113596" ] }, "reaction_10076891": { "compartment": "compartment_5460", "id": "reaction_10076891", "reactome": "R-BTA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10076888", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045076" ] }, "reaction_10087866": { "compartment": "compartment_70101", "id": "reaction_10087866", "reactome": "R-BTA-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068573" ], "products": [ "species_10067409" ], "modifiers": [], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067388": { "compartment": "compartment_984", "id": "reaction_10067388", "reactome": "R-BTA-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_3299686" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10067385", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10068575": { "compartment": "compartment_70101", "id": "reaction_10068575", "reactome": "R-BTA-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067407", "species_10068571" ], "products": [ "species_10068573" ], "modifiers": [], "additional_components": [ "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10069854": { "compartment": "compartment_17963", "id": "reaction_10069854", "reactome": "R-BTA-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069852" ], "products": [ "species_10067385" ], "modifiers": [], "additional_components": [ "F6R4N7", "ENSBTAT00000018580", "species_29426", "species_209799", "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10067731": { "compartment": "compartment_5460", "id": "reaction_10067731", "reactome": "R-BTA-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_1655882", "species_113600" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10067728", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10080786": { "compartment": "compartment_984", "id": "reaction_10080786", "reactome": "R-BTA-6799695", "name": "GPX5,6 reduce H2O2 to H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_1247892" ], "products": [ "species_109276", "species_3341331" ], "modifiers": [ [ "species_10080783", "catalyst" ] ], "additional_components": [ "A0A3Q1M7E3", "ENSBTAT00000068263", "F1MCF5", "ENSBTAT00000015939" ] }, "reaction_10067735": { "compartment": "compartment_70616", "id": "reaction_10067735", "reactome": "R-BTA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10038548" ], "products": [ "species_10038546", "species_189461" ], "modifiers": [], "additional_components": [ "P62894", "ENSBTAT00000007918", "CHEBI:38574", "CHEBI:38573", "P62894", "ENSBTAT00000007918" ] }, "reaction_10034166": { "compartment": "compartment_70101", "id": "reaction_10034166", "reactome": "R-BTA-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29450", "species_29366" ], "modifiers": [ [ "species_10034163", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10067722": { "compartment": "compartment_5460", "id": "reaction_10067722", "reactome": "R-BTA-3322995", "name": "PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_1614617" ], "products": [ "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067719", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "P35705", "ENSBTAT00000011505", "Q9BGI1", "ENSBTAT00000011403" ] }, "reaction_10068716": { "compartment": "compartment_17927", "id": "reaction_10068716", "reactome": "R-BTA-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10068713", "catalyst" ] ], "additional_components": [ "species_209799", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067375": { "compartment": "compartment_5460", "id": "reaction_10067375", "reactome": "R-BTA-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_3299683" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10067372", "catalyst" ] ], "additional_components": [ "E1BHL1", "ENSBTAT00000008569", "species_113527" ] }, "reaction_10067744": { "compartment": "compartment_70101", "id": "reaction_10067744", "reactome": "R-BTA-3343700", "name": "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_29408" ], "products": [ "species_29356", "species_111745" ], "modifiers": [ [ "species_10067741", "catalyst" ] ], "additional_components": [ "O77834", "ENSBTAT00000006383", "A0A3Q1LMV5", "ENSBTAT00000084460" ] }, "reaction_10068578": { "compartment": "compartment_5460", "id": "reaction_10068578", "reactome": "R-BTA-3697894", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_3697881" ], "products": [ "species_3697842", "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "ENSBTAT00000011403" ] }, "reaction_10067398": { "compartment": "compartment_70101", "id": "reaction_10067398", "reactome": "R-BTA-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29368", "species_29408" ], "modifiers": [ [ "species_10067395", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10066873": { "compartment": "compartment_7660", "id": "reaction_10066873", "reactome": "R-BTA-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066855", "species_29358" ], "products": [ "species_113582", "species_10066867" ], "modifiers": [ [ "species_10066855", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10066779": { "compartment": "compartment_7660", "id": "reaction_10066779", "reactome": "R-BTA-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_113671" ], "products": [ "species_10066770", "species_159939" ], "modifiers": [ [ "species_10066776", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10066876": { "compartment": "compartment_7660", "id": "reaction_10066876", "reactome": "R-BTA-3240295", "name": "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066770" ], "products": [ "species_77502", "species_10066768" ], "modifiers": [ [ "species_10044327", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10066832": { "compartment": "compartment_7660", "id": "reaction_10066832", "reactome": "R-BTA-3229089", "name": "PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_10066828" ], "products": [ "species_10066830" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179" ] }, "reaction_10066857": { "compartment": "compartment_7660", "id": "reaction_10066857", "reactome": "R-BTA-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066853" ], "products": [ "species_113582", "species_10066855" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10066786": { "compartment": "compartment_70101", "id": "reaction_10066786", "reactome": "R-BTA-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10066783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "ENSBTAT00000011949" ] }, "reaction_10088964": { "compartment": "compartment_7660", "id": "reaction_10088964", "reactome": "R-BTA-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066774", "species_111793" ], "products": [ "species_10066776" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063022", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10076298": { "compartment": "compartment_7660", "id": "reaction_10076298", "reactome": "R-BTA-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074450" ], "products": [ "species_113582", "species_10076295", "species_10074441" ], "modifiers": [ [ "species_10074450", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10074429": { "compartment": "compartment_7660", "id": "reaction_10074429", "reactome": "R-BTA-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074417", "species_10074425" ], "products": [ "species_10074427" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074431": { "compartment": "compartment_7660", "id": "reaction_10074431", "reactome": "R-BTA-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_3785706" ], "products": [ "species_10074417" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074446": { "compartment": "compartment_7660", "id": "reaction_10074446", "reactome": "R-BTA-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074438", "species_29358" ], "products": [ "species_113582", "species_10074443", "species_10074441" ], "modifiers": [ [ "species_10074438", "catalyst" ] ], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10078369": { "compartment": "compartment_7660", "id": "reaction_10078369", "reactome": "R-BTA-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074427" ], "products": [ "species_10074438", "species_2485002" ], "modifiers": [ [ "species_10074427", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074453": { "compartment": "compartment_7660", "id": "reaction_10074453", "reactome": "R-BTA-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074448" ], "products": [ "species_2485002", "species_10074450" ], "modifiers": [ [ "species_10074448", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10069684": { "compartment": "compartment_7660", "id": "reaction_10069684", "reactome": "R-BTA-4647593", "name": "EP400 binds CDKN1A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069680", "species_10069676" ], "products": [ "species_10069682" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000027216", "F1MLB1", "ENSBTAT00000027216", "P67939", "ENSBTAT00000001420" ] }, "reaction_10076343": { "compartment": "compartment_7660", "id": "reaction_10076343", "reactome": "R-BTA-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074425" ], "products": [ "species_10074448" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10068854": { "compartment": "compartment_7660", "id": "reaction_10068854", "reactome": "R-BTA-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_75165" ], "products": [ "species_10068852" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10066630": { "compartment": "compartment_7660", "id": "reaction_10066630", "reactome": "R-BTA-3209159", "name": "Phosphorylated ERF translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066626" ], "products": [ "species_10066628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000437", "ENSBTAT00000000437" ] }, "reaction_10091401": { "compartment": "compartment_17938", "id": "reaction_10091401", "reactome": "R-BTA-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091329" ], "products": [ "species_29372", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ], [ "species_10091399", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3B7L5", "ENSBTAT00000010532", "A0A3Q1MS15", "ENSBTAT00000083520", "A0A3Q1NF19", "ENSBTAT00000067422" ] }, "reaction_10091336": { "compartment": "compartment_17938", "id": "reaction_10091336", "reactome": "R-BTA-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10091329" ], "products": [ "species_29438", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091354": { "compartment": "compartment_17938", "id": "reaction_10091354", "reactome": "R-BTA-9640168", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091344" ], "products": [ "species_10091342", "species_10091338" ], "modifiers": [], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530" ] }, "reaction_10091356": { "compartment": "compartment_17938", "id": "reaction_10091356", "reactome": "R-BTA-9640175", "name": "v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091333", "species_10091338" ], "products": [ "species_10091340" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091404": { "compartment": "compartment_17938", "id": "reaction_10091404", "reactome": "R-BTA-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039057", "species_10091358" ], "products": [ "species_10091360" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091365": { "compartment": "compartment_17938", "id": "reaction_10091365", "reactome": "R-BTA-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091360" ], "products": [ "species_29372", "species_10091362" ], "modifiers": [ [ "species_10091360", "catalyst" ] ], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091351": { "compartment": "compartment_17938", "id": "reaction_10091351", "reactome": "R-BTA-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091340" ], "products": [ "species_29420", "species_10091344" ], "modifiers": [ [ "species_10091340", "catalyst" ], [ "species_10091349", "inhibitor" ] ], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "ENSBTAT00000087052" ] }, "reaction_10073481": { "compartment": "compartment_70101", "id": "reaction_10073481", "reactome": "R-BTA-5662986", "name": "MT2A binds copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_3299744" ], "products": [ "species_10073479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_3299744", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073464": { "compartment": "compartment_70101", "id": "reaction_10073464", "reactome": "R-BTA-5662613", "name": "MT3 exchanges zinc for copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073444", "species_209799" ], "products": [ "species_10073462", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "P37359", "ENSBTAT00000022460", "species_29426", "species_3299744", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073468": { "compartment": "compartment_70101", "id": "reaction_10073468", "reactome": "R-BTA-5662620", "name": "MT3 binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_1132098" ], "products": [ "species_10073466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_1132098", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073460": { "compartment": "compartment_70101", "id": "reaction_10073460", "reactome": "R-BTA-5662608", "name": "MT2A binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_1132098" ], "products": [ "species_10073458" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_1132098", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073446": { "compartment": "compartment_70101", "id": "reaction_10073446", "reactome": "R-BTA-5662606", "name": "MT3 binds zinc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_29426" ], "products": [ "species_10073444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_29426", "P37359", "ENSBTAT00000022460" ] }, "reaction_10075304": { "compartment": "compartment_7660", "id": "reaction_10075304", "reactome": "R-BTA-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075297" ], "products": [ "species_10075301", "species_30555" ], "modifiers": [ [ "species_10075297", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075323": { "compartment": "compartment_7660", "id": "reaction_10075323", "reactome": "R-BTA-5687673", "name": "MRN recruits LIG3:XRCC1 to MMEJ sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036900", "species_10075316" ], "products": [ "species_10075321" ], "modifiers": [], "additional_components": [ "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075306": { "compartment": "compartment_7660", "id": "reaction_10075306", "reactome": "R-BTA-5687465", "name": "MRN complex binds RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074778" ], "products": [ "species_10075297" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075326": { "compartment": "compartment_7660", "id": "reaction_10075326", "reactome": "R-BTA-5687675", "name": "LIG3 ligates remaining SSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075321" ], "products": [ "species_10035718", "species_10036900", "species_10074778", "species_5687670" ], "modifiers": [ [ "species_10075321", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075319": { "compartment": "compartment_7660", "id": "reaction_10075319", "reactome": "R-BTA-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075312" ], "products": [ "species_10075316", "species_68454", "species_10036890" ], "modifiers": [ [ "species_10075312", "catalyst" ] ], "additional_components": [ "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000000071", "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10086350": { "compartment": "compartment_876", "id": "reaction_10086350", "reactome": "R-BTA-8932955", "name": "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189227", "species_74113" ], "products": [ "species_83910", "species_189254" ], "modifiers": [ [ "species_10086347", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_188995", "species_70113", "species_70113", "species_188995", "ENSBTAT00000084455", "ENSBTAT00000055483" ] }, "reaction_10057350": { "compartment": "compartment_876", "id": "reaction_10057350", "reactome": "R-BTA-1296024", "name": "Activation of ATP sensitive Potassium channels in neuroendocrine cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057347", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q2KHY6", "ENSBTAT00000003307", "A2VDS4", "ENSBTAT00000021523", "E1BKR6", "ENSBTAT00000046676" ] }, "reaction_10057399": { "compartment": "compartment_876", "id": "reaction_10057399", "reactome": "R-BTA-1296045", "name": "Activation of Potassium transport channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057396", "catalyst" ] ], "additional_components": [ "A0A3Q1N684", "ENSBTAT00000081253" ] }, "reaction_10033473": { "compartment": "compartment_7660", "id": "reaction_10033473", "reactome": "R-BTA-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033469" ], "products": [ "species_10033471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083861", "ENSBTAT00000083861" ] }, "reaction_10084497": { "compartment": "compartment_7660", "id": "reaction_10084497", "reactome": "R-BTA-8857692", "name": "RNA demethylases demethylate N6-methyladenosine RNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8857725", "species_113671", "species_111793" ], "products": [ "species_8857850", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10084494", "catalyst" ] ], "additional_components": [ "species_71067", "A0A3Q1N5P9", "ENSBTAT00000081168", "A0A452DJ48", "ENSBTAT00000034976" ] }, "reaction_10090466": { "compartment": "compartment_70101", "id": "reaction_10090466", "reactome": "R-BTA-9025152", "name": "ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025151" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "CHEBI:138674", "CHEBI:138673", "ENSBTAT00000015911" ] }, "reaction_10090468": { "compartment": "compartment_70101", "id": "reaction_10090468", "reactome": "R-BTA-9025957", "name": "ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025960" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090477": { "compartment": "compartment_70101", "id": "reaction_10090477", "reactome": "R-BTA-9026408", "name": "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026407" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090470": { "compartment": "compartment_70101", "id": "reaction_10090470", "reactome": "R-BTA-9026003", "name": "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026047" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090472": { "compartment": "compartment_70101", "id": "reaction_10090472", "reactome": "R-BTA-9026006", "name": "ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026293" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090474": { "compartment": "compartment_70101", "id": "reaction_10090474", "reactome": "R-BTA-9026007", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_9026307", "species_29364" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10052888": { "compartment": "compartment_876", "id": "reaction_10052888", "reactome": "R-BTA-917807", "name": "holoTF:TFRC dimer translocates from plasma membrane to endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052876" ], "products": [ "species_10052886" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052923": { "compartment": "compartment_74700", "id": "reaction_10052923", "reactome": "R-BTA-917936", "name": "MCOLN1 transports Fe2+ from endosome lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917810" ], "products": [ "species_71067" ], "modifiers": [ [ "species_10052920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065500" ] }, "reaction_10052907": { "compartment": "compartment_70101", "id": "reaction_10052907", "reactome": "R-BTA-917814", "name": "apoTF:TFRC dimer translocates from endosome membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052903" ], "products": [ "species_10052905" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052925": { "compartment": "compartment_984", "id": "reaction_10052925", "reactome": "R-BTA-917987", "name": "TFRC dimer binds 2xholoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052874", "species_10052872" ], "products": [ "species_10052876" ], "modifiers": [], "additional_components": [ "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10052909": { "compartment": "compartment_171907", "id": "reaction_10052909", "reactome": "R-BTA-917835", "name": "Fe3+ dissociates from holoTF:TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052886" ], "products": [ "species_10052903", "species_917966" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052911": { "compartment": "compartment_947586", "id": "reaction_10052911", "reactome": "R-BTA-917839", "name": "apo-Transferrin dissociates from the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052905" ], "products": [ "species_10051000", "species_10052872" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421" ] }, "reaction_10076099": { "compartment": "compartment_876", "id": "reaction_10076099", "reactome": "R-BTA-5691154", "name": "HFE binds TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076095", "species_10052872" ], "products": [ "species_10076097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017371", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "Q5EEZ1", "ENSBTAT00000017371" ] }, "reaction_10052901": { "compartment": "compartment_171907", "id": "reaction_10052901", "reactome": "R-BTA-917811", "name": "STEAP3-like proteins reduce Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917882", "species_917966" ], "products": [ "species_917810" ], "modifiers": [ [ "species_10052898", "catalyst" ] ], "additional_components": [ "A0A3Q1LPT9", "ENSBTAT00000077862" ] }, "reaction_10036076": { "compartment": "compartment_7660", "id": "reaction_10036076", "reactome": "R-BTA-77585", "name": "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036050", "species_10036072" ], "products": [ "species_10036074" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10036052": { "compartment": "compartment_7660", "id": "reaction_10036052", "reactome": "R-BTA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036048", "species_10036044" ], "products": [ "species_10036050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10085967": { "compartment": "compartment_70101", "id": "reaction_10085967", "reactome": "R-BTA-8876312", "name": "SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876310", "species_74113" ], "products": [ "species_83910", "species_8876304" ], "modifiers": [ [ "species_10085964", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_113557", "species_373863", "species_197230", "ENSBTAT00000029140" ] }, "reaction_10048768": { "compartment": "compartment_876", "id": "reaction_10048768", "reactome": "R-BTA-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048765", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033777" ] }, "reaction_10048740": { "compartment": "compartment_876", "id": "reaction_10048740", "reactome": "R-BTA-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10048737", "catalyst" ] ], "additional_components": [ "E1BD54", "ENSBTAT00000045797", "E1B9J2", "ENSBTAT00000001818" ] }, "reaction_10052040": { "compartment": "compartment_70101", "id": "reaction_10052040", "reactome": "R-BTA-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_29432", "species_893599" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10064346": { "compartment": "compartment_984", "id": "reaction_10064346", "reactome": "R-BTA-2160492", "name": "IL4I1:FAD oxidises L-Phe to kPPV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_351993", "species_352327" ], "products": [ "species_2022135", "species_351629", "species_2160466" ], "modifiers": [ [ "species_10064343", "catalyst" ] ], "additional_components": [ "species_113596", "F1N191", "ENSBTAT00000007580" ] }, "reaction_10033935": { "compartment": "compartment_70101", "id": "reaction_10033935", "reactome": "R-BTA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10033932", "catalyst" ] ], "additional_components": [ "Q3ZBD3", "ENSBTAT00000015750" ] }, "reaction_10076974": { "compartment": "compartment_70101", "id": "reaction_10076974", "reactome": "R-BTA-5696365", "name": "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696361", "species_29356" ], "products": [ "species_29502", "species_29448", "species_5359061" ], "modifiers": [ [ "species_10076971", "catalyst" ] ], "additional_components": [ "Q32LE5", "ENSBTAT00000077904" ] }, "reaction_10033944": { "compartment": "compartment_70101", "id": "reaction_10033944", "reactome": "R-BTA-71164", "name": "homogentisate + O2 => maleylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30337" ], "products": [ "species_31135" ], "modifiers": [ [ "species_10033941", "catalyst" ] ], "additional_components": [ "A0A3Q1LS65", "ENSBTAT00000087453", "species_71067" ] }, "reaction_10033962": { "compartment": "compartment_70101", "id": "reaction_10033962", "reactome": "R-BTA-71181", "name": "fumarylacetoacetate => fumarate + acetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_31175" ], "products": [ "species_29666", "species_29586" ], "modifiers": [ [ "species_10033959", "catalyst" ] ], "additional_components": [ "A0A3Q1MPJ4", "ENSBTAT00000072597" ] }, "reaction_10033953": { "compartment": "compartment_70101", "id": "reaction_10033953", "reactome": "R-BTA-71173", "name": "maleylacetoacetate => fumarylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31135" ], "products": [ "species_31175" ], "modifiers": [ [ "species_10033950", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10075181": { "compartment": "compartment_7660", "id": "reaction_10075181", "reactome": "R-BTA-5686587", "name": "ABL1 phosphorylates RAD52", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10035844" ], "products": [ "species_113582", "species_10075178" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "A2VE43", "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617", "ENSBTAT00000080797" ] }, "reaction_10035846": { "compartment": "compartment_7660", "id": "reaction_10035846", "reactome": "R-BTA-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035842" ], "products": [ "species_10035844" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617" ] }, "reaction_10040183": { "compartment": "compartment_7660", "id": "reaction_10040183", "reactome": "R-BTA-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040167", "species_10040179", "species_10040175", "species_10040171" ], "products": [ "species_10040181" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026619", "ENSBTAT00000022773", "ENSBTAT00000012322", "ENSBTAT00000061540", "E1BC42", "ENSBTAT00000061540", "Q08E12", "ENSBTAT00000012322", "A2VE40", "ENSBTAT00000022773", "A4IFH4", "ENSBTAT00000026619" ] }, "reaction_10033504": { "compartment": "compartment_7660", "id": "reaction_10033504", "reactome": "R-BTA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10038904": { "compartment": "compartment_5460", "id": "reaction_10038904", "reactome": "R-BTA-163320", "name": "Association of mTERF with the termination sequence", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038900", "species_164569" ], "products": [ "species_10038902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063305", "G3N2I6", "ENSBTAT00000063305" ] }, "reaction_10040864": { "compartment": "compartment_12045", "id": "reaction_10040864", "reactome": "R-BTA-191072", "name": "Synthesis of Cx43", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10040862" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002398" ] }, "reaction_10055833": { "compartment": "compartment_70101", "id": "reaction_10055833", "reactome": "R-BTA-990489", "name": "Kinesin-13 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055577" ], "products": [ "species_10055579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023059", "F1N0Y3", "ENSBTAT00000023059" ] }, "reaction_10055515": { "compartment": "compartment_70101", "id": "reaction_10055515", "reactome": "R-BTA-983194", "name": "Kinesin-1 is a heterotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055511", "species_10055501" ], "products": [ "species_10055513" ], "modifiers": [], "additional_components": [ "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358" ] }, "reaction_10055645": { "compartment": "compartment_70101", "id": "reaction_10055645", "reactome": "R-BTA-983259", "name": "Kinesins move along microtubules consuming ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10055643" ], "products": [ "species_29370", "species_10055643" ], "modifiers": [], "additional_components": [ "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055823": { "compartment": "compartment_70101", "id": "reaction_10055823", "reactome": "R-BTA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055559" ], "products": [ "species_10055561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012347", "E1BF29", "ENSBTAT00000012347" ] }, "reaction_10055647": { "compartment": "compartment_70101", "id": "reaction_10055647", "reactome": "R-BTA-983266", "name": "Kinesins bind microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10055641" ], "products": [ "species_10055643" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055827": { "compartment": "compartment_70101", "id": "reaction_10055827", "reactome": "R-BTA-984671", "name": "Chromokinesins form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055825" ], "products": [ "species_10055555" ], "modifiers": [], "additional_components": [ "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936" ] }, "reaction_10055829": { "compartment": "compartment_70101", "id": "reaction_10055829", "reactome": "R-BTA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055565" ], "products": [ "species_10055567" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011898", "E1BG49", "ENSBTAT00000011898" ] }, "reaction_10055831": { "compartment": "compartment_70101", "id": "reaction_10055831", "reactome": "R-BTA-984733", "name": "Kinesin-3 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055533" ], "products": [ "species_10055535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035821", "E1BKE3", "ENSBTAT00000035821" ] }, "reaction_10090460": { "compartment": "compartment_70101", "id": "reaction_10090460", "reactome": "R-BTA-9024872", "name": "ALOX15 oxidises 17(S)-Hp-DHA to PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024012" ], "products": [ "species_9024883" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090386": { "compartment": "compartment_70101", "id": "reaction_10090386", "reactome": "R-BTA-9020262", "name": "ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024522" ], "products": [ "species_29364", "species_9024893" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090708": { "compartment": "compartment_12045", "id": "reaction_10090708", "reactome": "R-BTA-9037761", "name": "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024886", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9037755" ], "modifiers": [ [ "species_10090705", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094" ] }, "reaction_10091753": { "compartment": "compartment_70101", "id": "reaction_10091753", "reactome": "R-BTA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10084440" ], "products": [ "species_10085164" ], "modifiers": [], "additional_components": [ "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10084824": { "compartment": "compartment_70101", "id": "reaction_10084824", "reactome": "R-BTA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084753", "species_10075931" ], "products": [ "species_10084779" ], "modifiers": [], "additional_components": [ "A0A3Q1MWJ5", "ENSBTAT00000082605", "ENSBTAT00000028591", "A0A3Q1MWJ5", "ENSBTAT00000082605" ] }, "reaction_10085116": { "compartment": "compartment_876", "id": "reaction_10085116", "reactome": "R-BTA-8866269", "name": "ARRB bind GPCRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10085112" ], "products": [ "species_10085114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10085166": { "compartment": "compartment_876", "id": "reaction_10085166", "reactome": "R-BTA-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085160", "species_10084440" ], "products": [ "species_10085162" ], "modifiers": [ [ "species_10085164", "inhibitor" ] ], "additional_components": [ "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10085134": { "compartment": "compartment_70101", "id": "reaction_10085134", "reactome": "R-BTA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085126", "species_10085130" ], "products": [ "species_10085132" ], "modifiers": [], "additional_components": [ "G5E628", "ENSBTAT00000029117", "ENSBTAT00000084618", "A0A3Q1MSK9", "ENSBTAT00000084618", "G5E628", "ENSBTAT00000029117" ] }, "reaction_10085264": { "compartment": "compartment_876", "id": "reaction_10085264", "reactome": "R-BTA-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085260", "species_10045533" ], "products": [ "species_10085262" ], "modifiers": [], "additional_components": [ "A0A3Q1NKA6", "ENSBTAT00000070874", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1NKA6", "ENSBTAT00000070874" ] }, "reaction_10084819": { "compartment": "compartment_70101", "id": "reaction_10084819", "reactome": "R-BTA-8863721", "name": "NEDD8-STON binds TOR1 hexamer and COP9 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084815", "species_10084779", "species_10084793" ], "products": [ "species_10084817" ], "modifiers": [], "additional_components": [ "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10084757": { "compartment": "compartment_876", "id": "reaction_10084757", "reactome": "R-BTA-8863463", "name": "STON2 binds SYT proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084743", "species_10084753" ], "products": [ "species_10084755" ], "modifiers": [], "additional_components": [ "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553" ] }, "reaction_10084822": { "compartment": "compartment_70101", "id": "reaction_10084822", "reactome": "R-BTA-8863723", "name": "COP9 and TOR1 deneddylate STON2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084817" ], "products": [ "species_10084753", "species_10084815", "species_10075931", "species_10084793" ], "modifiers": [ [ "species_10084817", "catalyst" ] ], "additional_components": [ "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "ENSBTAT00000028591", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10089048": { "compartment": "compartment_70101", "id": "reaction_10089048", "reactome": "R-BTA-8981606", "name": "Myoglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089044", "species_29368" ], "products": [ "species_10089046" ], "modifiers": [], "additional_components": [ "species_71185", "P02192", "ENSBTAT00000084629", "species_113533", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10089058": { "compartment": "compartment_70101", "id": "reaction_10089058", "reactome": "R-BTA-8981610", "name": "Neuroglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_10089054" ], "products": [ "species_10089056" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533" ] }, "reaction_10089060": { "compartment": "compartment_70101", "id": "reaction_10089060", "reactome": "R-BTA-8981621", "name": "Neuroglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089056" ], "products": [ "species_29368", "species_10089054" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533", "species_71185", "Q6WZ19", "ENSBTAT00000021661" ] }, "reaction_10089062": { "compartment": "compartment_70101", "id": "reaction_10089062", "reactome": "R-BTA-8981622", "name": "Myoglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089046" ], "products": [ "species_10089044", "species_29368" ], "modifiers": [], "additional_components": [ "species_113533", "species_71185", "P02192", "ENSBTAT00000084629", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10049869": { "compartment": "compartment_876", "id": "reaction_10049869", "reactome": "R-BTA-446277", "name": "RhCG mediates ammonium efflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049628": { "compartment": "compartment_876", "id": "reaction_10049628", "reactome": "R-BTA-444393", "name": "RhCG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049871": { "compartment": "compartment_876", "id": "reaction_10049871", "reactome": "R-BTA-446278", "name": "RhBG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049635": { "compartment": "compartment_876", "id": "reaction_10049635", "reactome": "R-BTA-444419", "name": "RhBG mediates ammonium effflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049371": { "compartment": "compartment_876", "id": "reaction_10049371", "reactome": "R-BTA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10049368", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068742" ] }, "reaction_10049402": { "compartment": "compartment_876", "id": "reaction_10049402", "reactome": "R-BTA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10049399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072292" ] }, "reaction_10049378": { "compartment": "compartment_876", "id": "reaction_10049378", "reactome": "R-BTA-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10049375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014489" ] }, "reaction_10088912": { "compartment": "compartment_70101", "id": "reaction_10088912", "reactome": "R-BTA-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10088909", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005787" ] }, "reaction_10049358": { "compartment": "compartment_876", "id": "reaction_10049358", "reactome": "R-BTA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10049355", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "ENSBTAT00000074816" ] }, "reaction_10049060": { "compartment": "compartment_876", "id": "reaction_10049060", "reactome": "R-BTA-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_429130" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10049057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061504" ] }, "reaction_10049078": { "compartment": "compartment_876", "id": "reaction_10049078", "reactome": "R-BTA-429571", "name": "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429652", "species_74113" ], "products": [ "species_83910", "species_429648" ], "modifiers": [ [ "species_10049075", "catalyst" ] ], "additional_components": [ "CHEBI:27372", "species_426910", "species_426910", "CHEBI:27372", "ENSBTAT00000004510" ] }, "reaction_10049592": { "compartment": "compartment_876", "id": "reaction_10049592", "reactome": "R-BTA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10049589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035184" ] }, "reaction_10049613": { "compartment": "compartment_876", "id": "reaction_10049613", "reactome": "R-BTA-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10049610", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_209914", "species_390899", "species_209789", "species_209789", "CHEBI:28918", "species_390899", "species_159362", "species_209914", "ENSBTAT00000045811" ] }, "reaction_10049599": { "compartment": "compartment_876", "id": "reaction_10049599", "reactome": "R-BTA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10049596", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087022" ] }, "reaction_10049319": { "compartment": "compartment_876", "id": "reaction_10049319", "reactome": "R-BTA-433089", "name": "SOAT can transport taurolithocholate-3-sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433120", "species_74113" ], "products": [ "species_83910", "species_176483" ], "modifiers": [ [ "species_10049316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066284" ] }, "reaction_10049606": { "compartment": "compartment_876", "id": "reaction_10049606", "reactome": "R-BTA-444126", "name": "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10049603", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002712" ] }, "reaction_10049080": { "compartment": "compartment_876", "id": "reaction_10049080", "reactome": "R-BTA-429581", "name": "SLC5A6 transports vitamins from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429605", "species_74113" ], "products": [ "species_429627", "species_83910" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "CHEBI:16494", "species_199207", "species_196820", "species_199207", "species_196820", "CHEBI:16494", "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10051577": { "compartment": "compartment_20699", "id": "reaction_10051577", "reactome": "R-BTA-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051580": { "compartment": "compartment_20699", "id": "reaction_10051580", "reactome": "R-BTA-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051587": { "compartment": "compartment_20699", "id": "reaction_10051587", "reactome": "R-BTA-744230", "name": "SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_744239" ], "products": [ "species_113578", "species_744233" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026562" ] }, "reaction_10039874": { "compartment": "compartment_12045", "id": "reaction_10039874", "reactome": "R-BTA-174368", "name": "SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_162756" ], "products": [ "species_3499326", "species_174384" ], "modifiers": [ [ "species_10039871", "catalyst" ] ], "additional_components": [ "A2VE55", "ENSBTAT00000026562" ] }, "reaction_10051899": { "compartment": "compartment_876", "id": "reaction_10051899", "reactome": "R-BTA-879594", "name": "SLCO4C1 mediates the transport of digoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879521" ], "products": [ "species_879517" ], "modifiers": [ [ "species_10051896", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021761" ] }, "reaction_10051866": { "compartment": "compartment_876", "id": "reaction_10051866", "reactome": "R-BTA-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051863", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "E1BC23", "ENSBTAT00000026117", "E1BPV8", "ENSBTAT00000021795", "F1MM56", "ENSBTAT00000003345", "F1MYV0", "ENSBTAT00000030217" ] }, "reaction_10051843": { "compartment": "compartment_876", "id": "reaction_10051843", "reactome": "R-BTA-879528", "name": "SLCO2A1 transports PGT substrates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879566" ], "products": [ "species_879614" ], "modifiers": [ [ "species_10051840", "catalyst" ] ], "additional_components": [ "species_879535", "CHEBI:15544", "species_416911", "species_391930", "species_416911", "CHEBI:15544", "species_879535", "species_391930", "ENSBTAT00000001747" ] }, "reaction_10091250": { "compartment": "compartment_876", "id": "reaction_10091250", "reactome": "R-BTA-9631987", "name": "SLCO1B1 transports T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "ENSBTAT00000030217" ] }, "reaction_10051879": { "compartment": "compartment_876", "id": "reaction_10051879", "reactome": "R-BTA-879584", "name": "SLCO3A1 isoform 1 has abroad substrate specificity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051868" ], "products": [ "species_10051872" ], "modifiers": [ [ "species_10051876", "catalyst" ] ], "additional_components": [ "species_352326", "CHEBI:15544", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "CHEBI:15544", "species_352326", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "ENSBTAT00000055950" ] }, "reaction_10070928": { "compartment": "compartment_984", "id": "reaction_10070928", "reactome": "R-BTA-5229283", "name": "LCNs bind lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070924", "species_5229279" ], "products": [ "species_10070926" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576", "species_5229279", "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576" ] }, "reaction_10051892": { "compartment": "compartment_876", "id": "reaction_10051892", "reactome": "R-BTA-879585", "name": "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879559" ], "products": [ "species_879544" ], "modifiers": [ [ "species_10051889", "catalyst" ] ], "additional_components": [ "CHEBI:16196", "CHEBI:16196", "Q0VCQ2", "ENSBTAT00000020526", "A6QQD5", "ENSBTAT00000044112" ] }, "reaction_10036297": { "compartment": "compartment_70101", "id": "reaction_10036297", "reactome": "R-BTA-109539", "name": "Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179740", "species_74113" ], "products": [ "species_179741", "species_83910" ], "modifiers": [ [ "species_10036294", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83909", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "ENSBTAT00000021720" ] }, "reaction_10051545": { "compartment": "compartment_70101", "id": "reaction_10051545", "reactome": "R-BTA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "ENSBTAT00000010219" ] }, "reaction_10071001": { "compartment": "compartment_5460", "id": "reaction_10071001", "reactome": "R-BTA-5250210", "name": "ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070999" ], "products": [ "species_10070983" ], "modifiers": [], "additional_components": [ "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036283": { "compartment": "compartment_70101", "id": "reaction_10036283", "reactome": "R-BTA-109530", "name": "Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179738", "species_74113" ], "products": [ "species_179739", "species_83910" ], "modifiers": [ [ "species_10036280", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "CHEBI:17256", "CHEBI:17256", "species_83909", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000075356" ] }, "reaction_10051547": { "compartment": "compartment_70101", "id": "reaction_10051547", "reactome": "R-BTA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "ENSBTAT00000010219" ] }, "reaction_10071003": { "compartment": "compartment_70101", "id": "reaction_10071003", "reactome": "R-BTA-5250217", "name": "ARL2:GTP binds ARL2BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070997", "species_10070995" ], "products": [ "species_10070999" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006363", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10070991": { "compartment": "compartment_5460", "id": "reaction_10070991", "reactome": "R-BTA-5250209", "name": "ARL2:GTP:ARL2BP binds SLC25A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070983", "species_10070987" ], "products": [ "species_10070989" ], "modifiers": [], "additional_components": [ "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363", "ENSBTAT00000017580", "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10073838": { "compartment": "compartment_70616", "id": "reaction_10073838", "reactome": "R-BTA-5672027", "name": "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10070989", "catalyst" ] ], "additional_components": [ "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036290": { "compartment": "compartment_70101", "id": "reaction_10036290", "reactome": "R-BTA-109538", "name": "Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737", "species_74113" ], "products": [ "species_179743", "species_83910" ], "modifiers": [ [ "species_10036287", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000024328" ] }, "reaction_10036274": { "compartment": "compartment_70101", "id": "reaction_10036274", "reactome": "R-BTA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "ENSBTAT00000015948" ] }, "reaction_10036276": { "compartment": "compartment_70101", "id": "reaction_10036276", "reactome": "R-BTA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "ENSBTAT00000015948" ] }, "reaction_10038660": { "compartment": "compartment_70616", "id": "reaction_10038660", "reactome": "R-BTA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10038657", "catalyst" ] ], "additional_components": [ "P32007", "ENSBTAT00000063682" ] }, "reaction_10048747": { "compartment": "compartment_876", "id": "reaction_10048747", "reactome": "R-BTA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010384" ] }, "reaction_10085896": { "compartment": "compartment_70101", "id": "reaction_10085896", "reactome": "R-BTA-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_113529", "species_113552" ], "modifiers": [ [ "species_10085893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001624" ] }, "reaction_10049083": { "compartment": "compartment_876", "id": "reaction_10049083", "reactome": "R-BTA-429591", "name": "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10060218": { "compartment": "compartment_70616", "id": "reaction_10060218", "reactome": "R-BTA-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198498", "species_1614584" ], "products": [ "species_113544", "species_174375" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10048821": { "compartment": "compartment_201753", "id": "reaction_10048821", "reactome": "R-BTA-428052", "name": "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_428548" ], "products": [ "species_70106", "species_428614" ], "modifiers": [ [ "species_10048818", "catalyst" ] ], "additional_components": [ "A4FV52", "ENSBTAT00000009255", "A6QLI1", "ENSBTAT00000007935", "E1BA07", "ENSBTAT00000001445" ] }, "reaction_10049173": { "compartment": "compartment_876", "id": "reaction_10049173", "reactome": "R-BTA-429767", "name": "Passive I- efflux mediated by SMCT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015315" ] }, "reaction_10048601": { "compartment": "compartment_876", "id": "reaction_10048601", "reactome": "R-BTA-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_74113" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10048598", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076302" ] }, "reaction_10048618": { "compartment": "compartment_876", "id": "reaction_10048618", "reactome": "R-BTA-426155", "name": "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_352022" ], "products": [ "species_74126", "species_188972" ], "modifiers": [ [ "species_10048615", "catalyst" ] ], "additional_components": [ "E1BCI8", "ENSBTAT00000024019", "A0A3S5ZPL9", "ENSBTAT00000018852", "A0A3Q1NIV4", "ENSBTAT00000082311" ] }, "reaction_10048594": { "compartment": "compartment_876", "id": "reaction_10048594", "reactome": "R-BTA-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_188972", "species_74113" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10048591", "catalyst" ] ], "additional_components": [ "ENSBTAT00000046583" ] }, "reaction_10048795": { "compartment": "compartment_876", "id": "reaction_10048795", "reactome": "R-BTA-427998", "name": "Proton-coupled di- and tri-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428037" ], "products": [ "species_428026", "species_70106" ], "modifiers": [ [ "species_10048792", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:47923", "CHEBI:47923", "CHEBI:90799", "ENSBTAT00000001891" ] }, "reaction_10048802": { "compartment": "compartment_17938", "id": "reaction_10048802", "reactome": "R-BTA-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_427984" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10048799", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:90799", "CHEBI:46761", "species_29612", "ENSBTAT00000030236" ] }, "reaction_10048965": { "compartment": "compartment_201753", "id": "reaction_10048965", "reactome": "R-BTA-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428592", "species_428548" ], "products": [ "species_428632", "species_70106" ], "modifiers": [ [ "species_10048962", "catalyst" ] ], "additional_components": [ "species_29424", "species_428571", "species_428571", "species_29424", "ENSBTAT00000063578" ] }, "reaction_10048804": { "compartment": "compartment_876", "id": "reaction_10048804", "reactome": "R-BTA-428015", "name": "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428027", "species_29804", "species_74113" ], "products": [ "species_74126", "species_427997", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ] ], "additional_components": [ "species_427963", "CHEBI:17364", "species_210382", "species_427963", "CHEBI:17364", "species_210382", "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455" ] }, "reaction_10048491": { "compartment": "compartment_876", "id": "reaction_10048491", "reactome": "R-BTA-425483", "name": "SLC4A5,7,9 cotransport Na+ with 3HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_83910" ], "products": [ "species_425425", "species_74113" ], "modifiers": [ [ "species_10048488", "catalyst" ] ], "additional_components": [ "E1BBH7", "ENSBTAT00000006425", "E1BIN2", "ENSBTAT00000029024" ] }, "reaction_10048478": { "compartment": "compartment_876", "id": "reaction_10048478", "reactome": "R-BTA-425482", "name": "SLC4A1,2,3 exchanges HCO3- for Cl-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048475", "catalyst" ] ], "additional_components": [ "E1BKK3", "ENSBTAT00000019936", "A0A3Q1M051", "ENSBTAT00000071207" ] }, "reaction_10049053": { "compartment": "compartment_876", "id": "reaction_10049053", "reactome": "R-BTA-429094", "name": "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10049050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066412" ] }, "reaction_10089038": { "compartment": "compartment_70101", "id": "reaction_10089038", "reactome": "R-BTA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089035", "catalyst" ] ], "additional_components": [ "Q27994", "ENSBTAT00000012109" ] }, "reaction_10089024": { "compartment": "compartment_70101", "id": "reaction_10089024", "reactome": "R-BTA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089021", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889", "A0A3Q1MA30", "ENSBTAT00000042945" ] }, "reaction_10085907": { "compartment": "compartment_70101", "id": "reaction_10085907", "reactome": "R-BTA-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10085904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010116" ] }, "reaction_10089029": { "compartment": "compartment_70101", "id": "reaction_10089029", "reactome": "R-BTA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089026", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10049046": { "compartment": "compartment_876", "id": "reaction_10049046", "reactome": "R-BTA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10049043", "catalyst" ] ], "additional_components": [ "species_70113", "species_30034", "species_29532", "species_70113", "species_30034", "species_29532", "ENSBTAT00000079223" ] }, "reaction_10037913": { "compartment": "compartment_984", "id": "reaction_10037913", "reactome": "R-BTA-140777", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037910", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037899": { "compartment": "compartment_876", "id": "reaction_10037899", "reactome": "R-BTA-140761", "name": "sequestered tissue factor -> tissue factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037897" ], "products": [ "species_10037864" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009341", "ENSBTAT00000009341" ] }, "reaction_10037915": { "compartment": "compartment_984", "id": "reaction_10037915", "reactome": "R-BTA-140783", "name": "tissue factor (TF) + factor VII (F7) -> TF:F7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903", "species_10037864" ], "products": [ "species_10037910" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037887": { "compartment": "compartment_984", "id": "reaction_10037887", "reactome": "R-BTA-140736", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857", "species_74112" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037884", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10037937": { "compartment": "compartment_984", "id": "reaction_10037937", "reactome": "R-BTA-140825", "name": "TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037807", "species_10037884", "species_10037931" ], "products": [ "species_10037935" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016", "ENSBTAT00000085417", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "A0A3Q1NLA0", "ENSBTAT00000085417", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037906": { "compartment": "compartment_984", "id": "reaction_10037906", "reactome": "R-BTA-140769", "name": "factor VII -> factor VIIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903" ], "products": [ "species_10037893" ], "modifiers": [ [ "species_10037807", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037895": { "compartment": "compartment_984", "id": "reaction_10037895", "reactome": "R-BTA-140748", "name": "tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037893", "species_10037864" ], "products": [ "species_10037884" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10048635": { "compartment": "compartment_876", "id": "reaction_10048635", "reactome": "R-BTA-426223", "name": "Cation influx mediated by TRPC3/6/7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426219" ], "products": [ "species_426221" ], "modifiers": [ [ "species_10048630", "catalyst" ] ], "additional_components": [ "species_83910", "species_74016", "species_29926", "species_74016", "species_29926", "species_83910", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10037607": { "compartment": "compartment_876", "id": "reaction_10037607", "reactome": "R-BTA-139855", "name": "P2X1-mediated entry of Ca++ from plasma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10037604", "catalyst" ] ], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10044680": { "compartment": "compartment_7660", "id": "reaction_10044680", "reactome": "R-BTA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044676", "species_29428" ], "products": [ "species_10044678" ], "modifiers": [], "additional_components": [ "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096", "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096" ] }, "reaction_10044142": { "compartment": "compartment_13231", "id": "reaction_10044142", "reactome": "R-BTA-211206", "name": "Translocation of DFF to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044132" ], "products": [ "species_10044140" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044144": { "compartment": "compartment_7660", "id": "reaction_10044144", "reactome": "R-BTA-211207", "name": "Cleaved fragments of DFF45 dissociate from DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044108" ], "products": [ "species_10044098", "species_10044094", "species_10044106", "species_10044104" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000017999" ] }, "reaction_10044146": { "compartment": "compartment_70101", "id": "reaction_10044146", "reactome": "R-BTA-211224", "name": "Association of DFF40 with DFF45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044118", "species_10044120" ], "products": [ "species_10044122" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "ENSBTAT00000017999", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044116": { "compartment": "compartment_7660", "id": "reaction_10044116", "reactome": "R-BTA-211193", "name": "Homodimerization of DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044094" ], "products": [ "species_10044114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10066489": { "compartment": "compartment_70101", "id": "reaction_10066489", "reactome": "R-BTA-3000339", "name": "Phosphorylated BORA binds SCF-beta-TrCp1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10066480" ], "products": [ "species_10066482" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "ENSBTAT00000026496", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10065938": { "compartment": "compartment_70101", "id": "reaction_10065938", "reactome": "R-BTA-2562594", "name": "Phosphorylated OPTN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065934" ], "products": [ "species_10065936" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021808", "ENSBTAT00000021808" ] }, "reaction_10066487": { "compartment": "compartment_70101", "id": "reaction_10066487", "reactome": "R-BTA-3000335", "name": "SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066482", "species_10033408" ], "products": [ "species_10066484", "species_10056243" ], "modifiers": [ [ "species_10066482", "catalyst" ] ], "additional_components": [ "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3C9", "ENSBTAT00000026496", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10084216": { "compartment": "compartment_70101", "id": "reaction_10084216", "reactome": "R-BTA-8854052", "name": "Formation of the SCF-FBXL7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10039822", "species_10043871", "species_10039818" ], "products": [ "species_10084098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004177", "ENSBTAT00000068449", "ENSBTAT00000075328", "ENSBTAT00000035306", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177" ] }, "reaction_10084206": { "compartment": "compartment_70101", "id": "reaction_10084206", "reactome": "R-BTA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084100", "species_10033408" ], "products": [ "species_10084203" ], "modifiers": [ [ "species_10084100", "catalyst" ] ], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA06", "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084102": { "compartment": "compartment_70101", "id": "reaction_10084102", "reactome": "R-BTA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084098" ], "products": [ "species_10084100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084214": { "compartment": "compartment_70101", "id": "reaction_10084214", "reactome": "R-BTA-8854051", "name": "SCF-FBXL18 ubiquitinates FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10033408" ], "products": [ "species_10084209" ], "modifiers": [ [ "species_10084211", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004177", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F6PQR5", "ENSBTAT00000046646" ] }, "reaction_10039612": { "compartment": "compartment_13231", "id": "reaction_10039612", "reactome": "R-BTA-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039608" ], "products": [ "species_10039610" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10039614": { "compartment": "compartment_13231", "id": "reaction_10039614", "reactome": "R-BTA-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039610" ], "products": [ "species_10039608" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10084043": { "compartment": "compartment_70101", "id": "reaction_10084043", "reactome": "R-BTA-8852331", "name": "GTSE1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084039" ], "products": [ "species_10084041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009339", "ENSBTAT00000009339" ] }, "reaction_10084028": { "compartment": "compartment_70101", "id": "reaction_10084028", "reactome": "R-BTA-8852280", "name": "GTSE1 binds microtubule lattice in interphase cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10084024" ], "products": [ "species_10084026" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "species_29438", "species_29420" ] }, "reaction_10084047": { "compartment": "compartment_7660", "id": "reaction_10084047", "reactome": "R-BTA-8852337", "name": "GTSE1 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675", "species_10084041" ], "products": [ "species_10084045" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10084051": { "compartment": "compartment_70101", "id": "reaction_10084051", "reactome": "R-BTA-8852351", "name": "GTSE1 promotes translocation of TP53 to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084045" ], "products": [ "species_10084049" ], "modifiers": [], "additional_components": [ "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10087635": { "compartment": "compartment_70616", "id": "reaction_10087635", "reactome": "R-BTA-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039037" ], "products": [ "species_10087633" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326" ] }, "reaction_10052963": { "compartment": "compartment_70101", "id": "reaction_10052963", "reactome": "R-BTA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052929", "species_10052959" ], "products": [ "species_10052961" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027868", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10083789": { "compartment": "compartment_876", "id": "reaction_10083789", "reactome": "R-BTA-8849891", "name": "SALMs 1-3 bind to PSD-95 family members", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083783", "species_10083785" ], "products": [ "species_10083787" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778" ] }, "reaction_10083793": { "compartment": "compartment_876", "id": "reaction_10083793", "reactome": "R-BTA-8849900", "name": "SALMs1-3 bind each other in cis interactions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083785" ], "products": [ "species_10083791" ], "modifiers": [], "additional_components": [ "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10084356": { "compartment": "compartment_876", "id": "reaction_10084356", "reactome": "R-BTA-8855648", "name": "SALM3 binds LAR-RPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083779", "species_10046864" ], "products": [ "species_10084354" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053062", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10087862": { "compartment": "compartment_7660", "id": "reaction_10087862", "reactome": "R-BTA-8951676", "name": "RUNX3 binds TEADs and YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087858", "species_10084943" ], "products": [ "species_10087860" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10087997": { "compartment": "compartment_7660", "id": "reaction_10087997", "reactome": "R-BTA-8952058", "name": "CCND1 binds RUNX3 and displaces EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087908", "species_10056568" ], "products": [ "species_10053052", "species_10087995" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "ENSBTAT00000023277", "ENSBTAT00000021556", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087900": { "compartment": "compartment_7660", "id": "reaction_10087900", "reactome": "R-BTA-8951966", "name": "EP300 acetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10087887" ], "products": [ "species_2485002", "species_10087897" ], "modifiers": [ [ "species_10087887", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087889": { "compartment": "compartment_7660", "id": "reaction_10087889", "reactome": "R-BTA-8951951", "name": "RUNX3 binds EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084945", "species_10053052" ], "products": [ "species_10087887" ], "modifiers": [], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087910": { "compartment": "compartment_7660", "id": "reaction_10087910", "reactome": "R-BTA-8951977", "name": "Acetylated RUNX3 binds to BRD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087906", "species_10087897" ], "products": [ "species_10087908" ], "modifiers": [], "additional_components": [ "Q32S26", "ENSBTAT00000014704", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704" ] }, "reaction_10088006": { "compartment": "compartment_7660", "id": "reaction_10088006", "reactome": "R-BTA-8952069", "name": "HDAC4 deacetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10088001" ], "products": [ "species_10087906", "species_10088003", "species_427486" ], "modifiers": [ [ "species_10088001", "catalyst" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "A0A452DIV3", "ENSBTAT00000023277", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088012": { "compartment": "compartment_7660", "id": "reaction_10088012", "reactome": "R-BTA-8952128", "name": "RUNX3 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066677", "species_10084943" ], "products": [ "species_10088010" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "P67939", "ENSBTAT00000001420" ] }, "reaction_10086231": { "compartment": "compartment_7660", "id": "reaction_10086231", "reactome": "R-BTA-8878117", "name": "RUNX3 binds ZFHX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086227", "species_10084943" ], "products": [ "species_10086229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019489", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BPV9", "ENSBTAT00000019489" ] }, "reaction_10086587": { "compartment": "compartment_70101", "id": "reaction_10086587", "reactome": "R-BTA-8937807", "name": "SRC phosphorylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086579", "species_113592" ], "products": [ "species_29370", "species_10057248", "species_10086584" ], "modifiers": [ [ "species_10086579", "catalyst" ] ], "additional_components": [ "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088490": { "compartment": "compartment_7660", "id": "reaction_10088490", "reactome": "R-BTA-8952419", "name": "SMURFs ubiquitinate RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10036828" ], "products": [ "species_10088485" ], "modifiers": [ [ "species_10088487", "catalyst" ], [ "species_10053052", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000070567", "ENSBTAT00000043725", "ENSBTAT00000021556" ] }, "reaction_10086589": { "compartment": "compartment_70101", "id": "reaction_10086589", "reactome": "R-BTA-8937814", "name": "RUNX3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086577" ], "products": [ "species_10084943" ], "modifiers": [ [ "species_10057248", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567", "ENSBTAT00000011767" ] }, "reaction_10084947": { "compartment": "compartment_7660", "id": "reaction_10084947", "reactome": "R-BTA-8865454", "name": "CBFB binds RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10084939" ], "products": [ "species_10084945" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000021434", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088482": { "compartment": "compartment_7660", "id": "reaction_10088482", "reactome": "R-BTA-8952399", "name": "Polyubiquitinated RUNX3 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088478" ], "products": [ "species_10088480" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567" ] }, "reaction_10086581": { "compartment": "compartment_70101", "id": "reaction_10086581", "reactome": "R-BTA-8937792", "name": "RUNX3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10086577" ], "products": [ "species_10086579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040059": { "compartment": "compartment_7660", "id": "reaction_10040059", "reactome": "R-BTA-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040054", "species_10040050" ], "products": [ "species_10040056" ], "modifiers": [ [ "species_10040054", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525" ] }, "reaction_10040955": { "compartment": "compartment_70101", "id": "reaction_10040955", "reactome": "R-BTA-191636", "name": "Phosphorylation of Cx43 by c-src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040945" ], "products": [ "species_29370", "species_10040952" ], "modifiers": [ [ "species_10040945", "catalyst" ] ], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040961": { "compartment": "compartment_70101", "id": "reaction_10040961", "reactome": "R-BTA-191654", "name": "c-src associates with Cx43 in gap junctions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040959", "species_10040957" ], "products": [ "species_10040945" ], "modifiers": [], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040967": { "compartment": "compartment_876", "id": "reaction_10040967", "reactome": "R-BTA-191656", "name": "Closure of gap junction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040965" ], "products": [ "species_10040965" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398" ] }, "reaction_10085313": { "compartment": "compartment_876", "id": "reaction_10085313", "reactome": "R-BTA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060424", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076329" ] }, "reaction_10083179": { "compartment": "compartment_263163", "id": "reaction_10083179", "reactome": "R-BTA-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083175", "species_10083141" ], "products": [ "species_10083177" ], "modifiers": [], "additional_components": [ "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850" ] }, "reaction_10083149": { "compartment": "compartment_263163", "id": "reaction_10083149", "reactome": "R-BTA-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083119", "species_10083147" ], "products": [ "species_10083128" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438" ] }, "reaction_10083340": { "compartment": "compartment_432051", "id": "reaction_10083340", "reactome": "R-BTA-6814670", "name": "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083331" ], "products": [ "species_10083335", "species_10083333", "species_10083337" ], "modifiers": [ [ "species_10083331", "catalyst" ] ], "additional_components": [ "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "Q5EA50", "ENSBTAT00000074576", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "ENSBTAT00000015669", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083342": { "compartment": "compartment_263163", "id": "reaction_10083342", "reactome": "R-BTA-6814675", "name": "RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083329", "species_10083323" ], "products": [ "species_10083331" ], "modifiers": [], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083187": { "compartment": "compartment_70101", "id": "reaction_10083187", "reactome": "R-BTA-6814096", "name": "ARL1:GTP binds SCOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083183", "species_10083135" ], "products": [ "species_10083185" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065986", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "A0A3Q1M9K7", "ENSBTAT00000065986" ] }, "reaction_10083143": { "compartment": "compartment_263163", "id": "reaction_10083143", "reactome": "R-BTA-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083135", "species_10083128" ], "products": [ "species_10083141" ], "modifiers": [], "additional_components": [ "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767" ] }, "reaction_10083451": { "compartment": "compartment_20699", "id": "reaction_10083451", "reactome": "R-BTA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083439" ], "products": [ "species_10083449" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083425": { "compartment": "compartment_20699", "id": "reaction_10083425", "reactome": "R-BTA-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083421" ], "products": [ "species_10083423" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1MQ84", "ENSBTAT00000084706", "A0A3Q1MQ84", "ENSBTAT00000084706", "species_29438", "P84080", "ENSBTAT00000010159" ] }, "reaction_10083056": { "compartment": "compartment_20699", "id": "reaction_10083056", "reactome": "R-BTA-6811433", "name": "The COG tethering complex interacts with numerous SNAREs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083052" ], "products": [ "species_10083054" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10083458": { "compartment": "compartment_20699", "id": "reaction_10083458", "reactome": "R-BTA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083449" ], "products": [ "species_10083455" ], "modifiers": [ [ "species_10083449", "catalyst" ] ], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "P84080", "ENSBTAT00000010159", "species_29420", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083767": { "compartment": "compartment_20699", "id": "reaction_10083767", "reactome": "R-BTA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083763" ], "products": [ "species_10083765" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10065827": { "compartment": "compartment_876", "id": "reaction_10065827", "reactome": "R-BTA-2534346", "name": "SPAM1 Binds Hyaluronic Acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065823", "species_1297302" ], "products": [ "species_10065825" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045309", "species_1297302", "F1MZM9", "ENSBTAT00000045309" ] }, "reaction_10047292": { "compartment": "compartment_984", "id": "reaction_10047292", "reactome": "R-BTA-391155", "name": "SIRPA binds SFTPA oligomer, SFTPD oligomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047270", "species_10047288" ], "products": [ "species_10047290" ], "modifiers": [], "additional_components": [ "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380" ] }, "reaction_10060207": { "compartment": "compartment_70101", "id": "reaction_10060207", "reactome": "R-BTA-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_174369" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10060204", "catalyst" ] ], "additional_components": [ "species_71185", "F1MEW4", "ENSBTAT00000087445" ] }, "reaction_10060231": { "compartment": "compartment_70101", "id": "reaction_10060231", "reactome": "R-BTA-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_111707", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060275": { "compartment": "compartment_70101", "id": "reaction_10060275", "reactome": "R-BTA-1614654", "name": "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352015", "species_174369" ], "products": [ "species_174390", "species_1614585" ], "modifiers": [ [ "species_10060272", "catalyst" ] ], "additional_components": [ "species_29426", "A0A452DHV7", "ENSBTAT00000002916" ] }, "reaction_10057032": { "compartment": "compartment_70101", "id": "reaction_10057032", "reactome": "R-BTA-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_353106" ], "products": [ "species_1237165", "species_83951" ], "modifiers": [ [ "species_10057029", "catalyst" ] ], "additional_components": [ "Q3MHF7", "ENSBTAT00000048509" ] }, "reaction_10057023": { "compartment": "compartment_70101", "id": "reaction_10057023", "reactome": "R-BTA-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1237176" ], "products": [ "species_29372", "species_70106", "species_1237155" ], "modifiers": [ [ "species_10057020", "catalyst" ] ], "additional_components": [ "Q0VD27", "ENSBTAT00000019702", "species_29926" ] }, "reaction_10057684": { "compartment": "compartment_70101", "id": "reaction_10057684", "reactome": "R-BTA-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10057011", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003273" ] }, "reaction_10090681": { "compartment": "compartment_5460", "id": "reaction_10090681", "reactome": "R-BTA-9035484", "name": "CysS248-MPST:TXN2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090677" ], "products": [ "species_10089847", "species_10067705", "species_1655881" ], "modifiers": [], "additional_components": [ "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014", "ENSBTAT00000069079", "ENSBTAT00000000014" ] }, "reaction_10089850": { "compartment": "compartment_5460", "id": "reaction_10089850", "reactome": "R-BTA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090013": { "compartment": "compartment_5460", "id": "reaction_10090013", "reactome": "R-BTA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10060252": { "compartment": "compartment_70101", "id": "reaction_10060252", "reactome": "R-BTA-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111707" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060255": { "compartment": "compartment_70101", "id": "reaction_10060255", "reactome": "R-BTA-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_174369" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090015": { "compartment": "compartment_5460", "id": "reaction_10090015", "reactome": "R-BTA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090679": { "compartment": "compartment_5460", "id": "reaction_10090679", "reactome": "R-BTA-9035227", "name": "TXN2 binds CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_10090669" ], "products": [ "species_10090677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000069079", "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014" ] }, "reaction_10060361": { "compartment": "compartment_5460", "id": "reaction_10060361", "reactome": "R-BTA-1655879", "name": "Thiosulfate can transfer its sulfur atom to glutathione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_113529", "species_1655887" ], "products": [ "species_1655882", "species_1614538", "species_1655881" ], "modifiers": [ [ "species_10060358", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023735" ] }, "reaction_10060216": { "compartment": "compartment_5460", "id": "reaction_10060216", "reactome": "R-BTA-1614544", "name": "Sulfite is oxidized to sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_1614538", "species_113521" ], "products": [ "species_1614617", "species_1614584" ], "modifiers": [ [ "species_10060213", "catalyst" ] ], "additional_components": [ "Q3MHX0", "ENSBTAT00000008101", "species_947539" ] }, "reaction_10060250": { "compartment": "compartment_70616", "id": "reaction_10060250", "reactome": "R-BTA-1614605", "name": "Persulfide sulfur is dioxygenated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10060239", "species_113521" ], "products": [ "species_10060241", "species_113529", "species_1614538" ], "modifiers": [ [ "species_10060247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013690", "ENSBTAT00000013690", "Q3T094", "ENSBTAT00000005747", "species_29426" ] }, "reaction_10060264": { "compartment": "compartment_70101", "id": "reaction_10060264", "reactome": "R-BTA-1614645", "name": "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29368" ], "products": [ "species_1614519" ], "modifiers": [ [ "species_10060261", "catalyst" ] ], "additional_components": [ "A0A3Q1MCZ5", "ENSBTAT00000079843", "species_71067" ] }, "reaction_10060234": { "compartment": "compartment_70101", "id": "reaction_10060234", "reactome": "R-BTA-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614582", "species_1614532" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090671": { "compartment": "compartment_5460", "id": "reaction_10090671", "reactome": "R-BTA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089847", "species_9012592" ], "products": [ "species_113557", "species_10090669" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079", "ENSBTAT00000069079", "ENSBTAT00000069079" ] }, "reaction_10083204": { "compartment": "compartment_70101", "id": "reaction_10083204", "reactome": "R-BTA-6814153", "name": "ADO oxidises 2AET to HTAU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_6814151" ], "products": [ "species_1655445", "species_70106" ], "modifiers": [ [ "species_10083201", "catalyst" ] ], "additional_components": [ "G3MZK0", "ENSBTAT00000064438", "species_71067" ] }, "reaction_10060228": { "compartment": "compartment_70101", "id": "reaction_10060228", "reactome": "R-BTA-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10089959": { "compartment": "compartment_5460", "id": "reaction_10089959", "reactome": "R-BTA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10089956", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043317" ] }, "reaction_10077124": { "compartment": "compartment_70101", "id": "reaction_10077124", "reactome": "R-BTA-5696838", "name": "BHMT2 tetramer transfers CH3 group from SMM to LHCYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4789070", "species_174369" ], "products": [ "species_70106", "species_174390" ], "modifiers": [ [ "species_10077121", "catalyst" ] ], "additional_components": [ "species_29426", "F1N4C6", "ENSBTAT00000048928" ] }, "reaction_10078575": { "compartment": "compartment_5460", "id": "reaction_10078575", "reactome": "R-BTA-6797913", "name": "SARDH:FAD oxidatively demethylates SARC to Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6797917", "species_113521" ], "products": [ "species_159549", "species_6797920" ], "modifiers": [ [ "species_10078572", "catalyst" ] ], "additional_components": [ "A0A3Q1MR10", "ENSBTAT00000075705", "species_113596" ] }, "reaction_10078582": { "compartment": "compartment_5460", "id": "reaction_10078582", "reactome": "R-BTA-6797961", "name": "CHDH oxidises Cho to BETALD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_6798162" ], "products": [ "species_6798194", "species_31649" ], "modifiers": [ [ "species_10078579", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013227" ] }, "reaction_10044844": { "compartment": "compartment_70101", "id": "reaction_10044844", "reactome": "R-BTA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10044841", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006978" ] }, "reaction_10044851": { "compartment": "compartment_70101", "id": "reaction_10044851", "reactome": "R-BTA-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10044848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054971" ] }, "reaction_10033778": { "compartment": "compartment_70101", "id": "reaction_10033778", "reactome": "R-BTA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10033775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005575" ] }, "reaction_10033788": { "compartment": "compartment_70101", "id": "reaction_10033788", "reactome": "R-BTA-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_508182" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10033785", "catalyst" ] ], "additional_components": [ "CHEBI:57427", "CHEBI:58045", "species_29702", "CHEBI:28654", "CHEBI:17865", "CHEBI:16530", "A0A3Q1ML78", "ENSBTAT00000086973" ] }, "reaction_10033806": { "compartment": "compartment_5460", "id": "reaction_10033806", "reactome": "R-BTA-70785", "name": "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70772", "species_113521" ], "products": [ "species_70784" ], "modifiers": [ [ "species_10033803", "catalyst" ] ], "additional_components": [ "A0A3Q1M9N4", "ENSBTAT00000068139" ] }, "reaction_10051185": { "compartment": "compartment_5460", "id": "reaction_10051185", "reactome": "R-BTA-508369", "name": "alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_70836", "species_29362" ], "products": [ "species_70829", "species_113526" ], "modifiers": [ [ "species_10033812", "catalyst" ] ], "additional_components": [ "O02691", "ENSBTAT00000023642" ] }, "reaction_10033824": { "compartment": "compartment_5460", "id": "reaction_10033824", "reactome": "R-BTA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10033797": { "compartment": "compartment_5460", "id": "reaction_10033797", "reactome": "R-BTA-70745", "name": "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_70715" ], "products": [ "species_70744", "species_31649" ], "modifiers": [ [ "species_10033794", "catalyst" ] ], "additional_components": [ "A0A452DI40", "ENSBTAT00000005782", "species_113596" ] }, "reaction_10052027": { "compartment": "compartment_70101", "id": "reaction_10052027", "reactome": "R-BTA-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10052024", "catalyst" ] ], "additional_components": [ "species_71185", "E1BPE1", "ENSBTAT00000007525" ] }, "reaction_10052043": { "compartment": "compartment_70101", "id": "reaction_10052043", "reactome": "R-BTA-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_29432", "species_893615" ], "modifiers": [ [ "species_10052037", "catalyst" ], [ "species_29502", "inhibitor" ], [ "species_8939576", "inhibitor" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10033979": { "compartment": "compartment_70101", "id": "reaction_10033979", "reactome": "R-BTA-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34351", "species_29356" ], "products": [ "species_29432", "species_30487" ], "modifiers": [ [ "species_10033976", "catalyst" ] ], "additional_components": [ "A0A3Q1MB81", "ENSBTAT00000069075" ] }, "reaction_10052030": { "compartment": "compartment_5460", "id": "reaction_10052030", "reactome": "R-BTA-893583", "name": "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_893607" ], "products": [ "species_893617", "species_113552" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10033969": { "compartment": "compartment_70101", "id": "reaction_10033969", "reactome": "R-BTA-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_29970" ], "products": [ "species_34351", "species_29356", "species_29366" ], "modifiers": [ [ "species_10033966", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073847" ] }, "reaction_10085381": { "compartment": "compartment_876", "id": "reaction_10085381", "reactome": "R-BTA-8870352", "name": "SLC36A4 transports L-Trp from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352006" ], "products": [ "species_29500" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10033988": { "compartment": "compartment_70101", "id": "reaction_10033988", "reactome": "R-BTA-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10033985", "catalyst" ] ], "additional_components": [ "A0A452DIN3", "ENSBTAT00000006132", "species_71067" ] }, "reaction_10041894": { "compartment": "compartment_70101", "id": "reaction_10041894", "reactome": "R-BTA-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10041891", "catalyst" ] ], "additional_components": [ "species_71185", "A0A3Q1LFW8", "ENSBTAT00000070085" ] }, "reaction_10090155": { "compartment": "compartment_70101", "id": "reaction_10090155", "reactome": "R-BTA-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_29356", "species_9014643" ], "modifiers": [ [ "species_10090152", "catalyst" ] ], "additional_components": [ "A5PKH5", "ENSBTAT00000011776" ] }, "reaction_10090162": { "compartment": "compartment_70101", "id": "reaction_10090162", "reactome": "R-BTA-9014641", "name": "HRSP12 deaminates 2AA to 2OBUTA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9014643" ], "products": [ "species_29382", "species_936714" ], "modifiers": [ [ "species_10090159", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016718" ] }, "reaction_10065455": { "compartment": "compartment_70101", "id": "reaction_10065455", "reactome": "R-BTA-2408524", "name": "Sec is reduced to H2Se by PXLP-K259-SCLY dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5359016", "species_5357697" ], "products": [ "species_5357660", "species_29432", "species_5359011" ], "modifiers": [ [ "species_10065452", "catalyst" ] ], "additional_components": [ "A2VDS1", "ENSBTAT00000013719" ] }, "reaction_10054601": { "compartment": "compartment_70101", "id": "reaction_10054601", "reactome": "R-BTA-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_29372", "species_200736" ], "modifiers": [ [ "species_10054598", "catalyst" ] ], "additional_components": [ "species_29926", "Q2KHU0", "ENSBTAT00000017392" ] }, "reaction_10054620": { "compartment": "compartment_70101", "id": "reaction_10054620", "reactome": "R-BTA-977348", "name": "PHGHD tetramer dehydrogenates 3PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29728" ], "products": [ "species_977329", "species_70106", "species_73473" ], "modifiers": [ [ "species_10054617", "catalyst" ] ], "additional_components": [ "A0A140T866", "ENSBTAT00000008907" ] }, "reaction_10090172": { "compartment": "compartment_70101", "id": "reaction_10090172", "reactome": "R-BTA-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10090175": { "compartment": "compartment_70101", "id": "reaction_10090175", "reactome": "R-BTA-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10054611": { "compartment": "compartment_70101", "id": "reaction_10054611", "reactome": "R-BTA-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977329", "species_29404" ], "products": [ "species_29406", "species_936706" ], "modifiers": [ [ "species_10054608", "catalyst" ] ], "additional_components": [ "A0A3S5ZPF7", "ENSBTAT00000018554" ] }, "reaction_10086371": { "compartment": "compartment_70101", "id": "reaction_10086371", "reactome": "R-BTA-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10086368", "catalyst" ] ], "additional_components": [ "A4FUZ5", "ENSBTAT00000002833", "A0A3Q1LF32", "ENSBTAT00000072137" ] }, "reaction_10090647": { "compartment": "compartment_70101", "id": "reaction_10090647", "reactome": "R-BTA-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10051165": { "compartment": "compartment_5460", "id": "reaction_10051165", "reactome": "R-BTA-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113593", "species_113600", "species_113552" ], "products": [ "species_113548", "species_113581", "species_31339", "species_113563" ], "modifiers": [ [ "species_10051162", "catalyst" ] ], "additional_components": [ "Q2KJH7", "ENSBTAT00000015703" ] }, "reaction_10077453": { "compartment": "compartment_70101", "id": "reaction_10077453", "reactome": "R-BTA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10077450", "catalyst" ] ], "additional_components": [ "Q58D08", "ENSBTAT00000022364" ] }, "reaction_10087455": { "compartment": "compartment_70101", "id": "reaction_10087455", "reactome": "R-BTA-8942575", "name": "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_5691492" ], "products": [ "species_29370", "species_5693762" ], "modifiers": [ [ "species_10087452", "catalyst" ] ], "additional_components": [ "Q0VCE9", "ENSBTAT00000004262", "F1N0M1", "ENSBTAT00000023262" ] }, "reaction_10052046": { "compartment": "compartment_70101", "id": "reaction_10052046", "reactome": "R-BTA-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29472" ], "products": [ "species_29432", "species_893598" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10077444": { "compartment": "compartment_5460", "id": "reaction_10077444", "reactome": "R-BTA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10077441", "catalyst" ] ], "additional_components": [ "Q17QJ7", "ENSBTAT00000000047" ] }, "reaction_10077864": { "compartment": "compartment_5460", "id": "reaction_10077864", "reactome": "R-BTA-6788611", "name": "HYKK phosphorylates 5HLYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788606", "species_113573" ], "products": [ "species_5696409", "species_113525" ], "modifiers": [ [ "species_10077861", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067508" ] }, "reaction_10077435": { "compartment": "compartment_17951", "id": "reaction_10077435", "reactome": "R-BTA-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_5693325" ], "products": [ "species_113575", "species_6783877" ], "modifiers": [ [ "species_10077432", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010444" ] }, "reaction_10045036": { "compartment": "compartment_5460", "id": "reaction_10045036", "reactome": "R-BTA-372480", "name": "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113577" ], "products": [ "species_29406", "species_70951" ], "modifiers": [ [ "species_10045033", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077809" ] }, "reaction_10051198": { "compartment": "compartment_5460", "id": "reaction_10051198", "reactome": "R-BTA-508561", "name": "alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70951", "species_113552" ], "products": [ "species_113594", "species_508531" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10076261": { "compartment": "compartment_17951", "id": "reaction_10076261", "reactome": "R-BTA-5693347", "name": "CRYM reduces P2C to PPCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_5693311", "species_113602" ], "products": [ "species_5693325", "species_389556" ], "modifiers": [ [ "species_10076258", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012972" ] }, "reaction_10033997": { "compartment": "compartment_17927", "id": "reaction_10033997", "reactome": "R-BTA-71275", "name": "arginine + glycine => ornithine + guanidoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113530", "species_113545" ], "products": [ "species_113543", "species_113586" ], "modifiers": [ [ "species_10033994", "catalyst" ] ], "additional_components": [ "Q2HJ74", "ENSBTAT00000007338" ] }, "reaction_10042847": { "compartment": "compartment_70616", "id": "reaction_10042847", "reactome": "R-BTA-200326", "name": "creatine + ATP => phosphocreatine + ADP [CK octamer]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042844", "catalyst" ] ], "additional_components": [ "Q9TTK8", "ENSBTAT00000009871" ] }, "reaction_10034004": { "compartment": "compartment_70101", "id": "reaction_10034004", "reactome": "R-BTA-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_29916", "species_70106", "species_71285" ], "modifiers": [ [ "species_10034001", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005375" ] }, "reaction_10042838": { "compartment": "compartment_70101", "id": "reaction_10042838", "reactome": "R-BTA-200318", "name": "creatine + ATP => phosphocreatine + ADP [CKB,CKM]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042835", "catalyst" ] ], "additional_components": [ "Q5EA61", "ENSBTAT00000050490" ] }, "reaction_10066232": { "compartment": "compartment_70101", "id": "reaction_10066232", "reactome": "R-BTA-2752067", "name": "BESTs transport cytosolic HCO3- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627" ], "products": [ "species_425425" ], "modifiers": [ [ "species_10066224", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10084767": { "compartment": "compartment_876", "id": "reaction_10084767", "reactome": "R-BTA-8863494", "name": "ASICs bind STOML3, (STOM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065958", "species_10084763" ], "products": [ "species_10084765" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "F1MCB3", "ENSBTAT00000024268", "F1MCB3", "ENSBTAT00000024268", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10091583": { "compartment": "compartment_70101", "id": "reaction_10091583", "reactome": "R-BTA-9659568", "name": "ANO1 transports cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065970", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067569" ] }, "reaction_10066206": { "compartment": "compartment_70101", "id": "reaction_10066206", "reactome": "R-BTA-2744242", "name": "TTYH2/3 transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066203", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080053" ] }, "reaction_10066270": { "compartment": "compartment_984", "id": "reaction_10066270", "reactome": "R-BTA-2872444", "name": "SLC9B1/C2 exchange Na+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10066267", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027774" ] }, "reaction_10066289": { "compartment": "compartment_17927", "id": "reaction_10066289", "reactome": "R-BTA-2889070", "name": "SLC9B2 exchanges Na+, Li+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_2889081" ], "products": [ "species_2889062", "species_163953" ], "modifiers": [ [ "species_10066286", "catalyst" ] ], "additional_components": [ "species_83910", "species_8953505", "species_8953505", "species_83910", "ENSBTAT00000085969" ] }, "reaction_10066227": { "compartment": "compartment_70101", "id": "reaction_10066227", "reactome": "R-BTA-2744361", "name": "BESTs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066224", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10066034": { "compartment": "compartment_70101", "id": "reaction_10066034", "reactome": "R-BTA-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_74722", "species_352022" ], "modifiers": [ [ "species_10066031", "catalyst" ] ], "additional_components": [ "G3N3A9", "ENSBTAT00000064202", "E1BK15", "ENSBTAT00000027587" ] }, "reaction_10066004": { "compartment": "compartment_161320", "id": "reaction_10066004", "reactome": "R-BTA-2685505", "name": "TPCN1/2 transport lysosomal Ca2+ to cytosol ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606834" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10066001", "catalyst" ], [ "species_2730676", "catalyst" ] ], "additional_components": [ "A0A3Q1MQ38", "ENSBTAT00000082890", "A0A3Q1N2G9", "ENSBTAT00000077727" ] }, "reaction_10066199": { "compartment": "compartment_70101", "id": "reaction_10066199", "reactome": "R-BTA-2744228", "name": "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066196", "catalyst" ] ], "additional_components": [ "E1BLQ0", "ENSBTAT00000012099", "E1BEP9", "ENSBTAT00000017615", "E1B792", "ENSBTAT00000049019" ] }, "reaction_10091542": { "compartment": "compartment_876", "id": "reaction_10091542", "reactome": "R-BTA-9650165", "name": "ASIC trimers bind H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10091540" ], "products": [ "species_10065958" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "F1MGK7", "ENSBTAT00000061078", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10066282": { "compartment": "compartment_70101", "id": "reaction_10066282", "reactome": "R-BTA-2872498", "name": "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_83910" ], "products": [ "species_113551", "species_2892454" ], "modifiers": [ [ "species_10066279", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065965": { "compartment": "compartment_70101", "id": "reaction_10065965", "reactome": "R-BTA-2671885", "name": "ASIC trimers:H+ transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10065958", "catalyst" ], [ "species_2672379", "inhibitor" ], [ "species_2672383", "inhibitor" ], [ "species_10065963", "inhibitor" ] ], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "ENSBTAT00000027364" ] }, "reaction_10066021": { "compartment": "compartment_70101", "id": "reaction_10066021", "reactome": "R-BTA-2730664", "name": "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10066018", "catalyst" ], [ "species_74016", "inhibitor" ] ], "additional_components": [ "A0A3Q1LL71", "ENSBTAT00000082451", "G3N0G4", "ENSBTAT00000065331", "F1MJ95", "ENSBTAT00000020495" ] }, "reaction_10066277": { "compartment": "compartment_70101", "id": "reaction_10066277", "reactome": "R-BTA-2872497", "name": "SLC17A3-2 transports cytosolic urate to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30034" ], "products": [ "species_429056" ], "modifiers": [ [ "species_10066274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065991": { "compartment": "compartment_70101", "id": "reaction_10065991", "reactome": "R-BTA-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065988", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A0A3Q1M2M7", "ENSBTAT00000073921", "E1BJF8", "ENSBTAT00000022706", "A0A3Q1MCG6", "ENSBTAT00000067569", "A0A3Q1LNC2", "ENSBTAT00000071379", "A0A3Q1MUE0", "ENSBTAT00000078140" ] }, "reaction_10049035": { "compartment": "compartment_70101", "id": "reaction_10049035", "reactome": "R-BTA-428917", "name": "G13 activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049028" ], "products": [ "species_29420", "species_10049032" ], "modifiers": [ [ "species_10049028", "catalyst" ] ], "additional_components": [ "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "G5E6P3", "ENSBTAT00000062941", "species_29438", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959" ] }, "reaction_10091701": { "compartment": "compartment_70101", "id": "reaction_10091701", "reactome": "R-BTA-9674529", "name": "AAMP binds to TBXA2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045856", "species_10091695" ], "products": [ "species_10091699" ], "modifiers": [ [ "species_391932", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000019892", "ENSBTAT00000005126", "Q3SZK1", "ENSBTAT00000005126", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10049014": { "compartment": "compartment_70101", "id": "reaction_10049014", "reactome": "R-BTA-428750", "name": "Gq activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049009" ], "products": [ "species_29420", "species_10049011" ], "modifiers": [ [ "species_10049009", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10048059": { "compartment": "compartment_70101", "id": "reaction_10048059", "reactome": "R-BTA-419003", "name": "Interaction of Nectins with Afadin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055", "species_10048049" ], "products": [ "species_10048057" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "ENSBTAT00000083796", "A0A3Q1LN46", "ENSBTAT00000083796", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048045": { "compartment": "compartment_204883", "id": "reaction_10048045", "reactome": "R-BTA-419001", "name": "Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_140648", "species_10048041" ], "products": [ "species_10048043" ], "modifiers": [], "additional_components": [ "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042", "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042" ] }, "reaction_10048348": { "compartment": "compartment_204883", "id": "reaction_10048348", "reactome": "R-BTA-420592", "name": "Transhomodimerization of Nectin-like (Necl) proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048344" ], "products": [ "species_10048346" ], "modifiers": [], "additional_components": [ "A0A3Q1M7P7", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841" ] }, "reaction_10048065": { "compartment": "compartment_204883", "id": "reaction_10048065", "reactome": "R-BTA-419011", "name": "Transhomodimerization of Nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048061" ], "products": [ "species_10048063" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048334": { "compartment": "compartment_204883", "id": "reaction_10048334", "reactome": "R-BTA-420584", "name": "Necl-1:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10048330" ], "products": [ "species_10048332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048352": { "compartment": "compartment_204883", "id": "reaction_10048352", "reactome": "R-BTA-420593", "name": "PVR:PVRL3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10042235" ], "products": [ "species_10048350" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070790", "A0A3Q1MRJ9", "ENSBTAT00000070790", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048342": { "compartment": "compartment_204883", "id": "reaction_10048342", "reactome": "R-BTA-420591", "name": "Nectin-2:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048338", "species_10048336" ], "products": [ "species_10048340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396" ] }, "reaction_10049335": { "compartment": "compartment_876", "id": "reaction_10049335", "reactome": "R-BTA-433711", "name": "Cis-homodimerization of nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055" ], "products": [ "species_10048061" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10044043": { "compartment": "compartment_70101", "id": "reaction_10044043", "reactome": "R-BTA-210294", "name": "Interaction of PECAM-1 and SHP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10044014" ], "products": [ "species_10044041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10049290": { "compartment": "compartment_70101", "id": "reaction_10049290", "reactome": "R-BTA-432148", "name": "Fgr may phosphorylate p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10049287", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "ENSBTAT00000078914" ] }, "reaction_10049283": { "compartment": "compartment_70101", "id": "reaction_10049283", "reactome": "R-BTA-432143", "name": "PECAM-1 binds PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041566", "species_10044014" ], "products": [ "species_10049281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044018": { "compartment": "compartment_70101", "id": "reaction_10044018", "reactome": "R-BTA-210277", "name": "Interaction of PECAM-1 and SHP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043836" ], "products": [ "species_10044016" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000077529", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10049364": { "compartment": "compartment_876", "id": "reaction_10049364", "reactome": "R-BTA-435244", "name": "PECAM1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044026" ], "products": [ "species_29370", "species_10044014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000086833" ] }, "reaction_10085323": { "compartment": "compartment_12045", "id": "reaction_10085323", "reactome": "R-BTA-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8869214" ], "products": [ "species_29416", "species_8869207" ], "modifiers": [ [ "species_10085320", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006727" ] }, "reaction_10048182": { "compartment": "compartment_984", "id": "reaction_10048182", "reactome": "R-BTA-419490", "name": "Binding of ATP to P2X receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037602", "species_114570" ], "products": [ "species_10037604" ], "modifiers": [], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10072426": { "compartment": "compartment_20699", "id": "reaction_10072426", "reactome": "R-BTA-5623513", "name": "ASAP1 stimulates GTPase activity of ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10072421" ], "products": [ "species_10072423", "species_29372", "species_10072399" ], "modifiers": [ [ "species_10072421", "catalyst" ] ], "additional_components": [ "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "P02699", "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072401": { "compartment": "compartment_70101", "id": "reaction_10072401", "reactome": "R-BTA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10072399" ], "products": [ "species_29420", "species_10072322" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10072326": { "compartment": "compartment_20699", "id": "reaction_10072326", "reactome": "R-BTA-5620914", "name": "ARF4:GTP binds VxPx-motifs of membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623403", "species_10072322" ], "products": [ "species_10072324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072475": { "compartment": "compartment_261122", "id": "reaction_10072475", "reactome": "R-BTA-5624127", "name": "ARL6:GTP and the BBSome target cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072451" ], "products": [ "species_10072467" ], "modifiers": [ [ "species_10072473", "inhibitor" ] ], "additional_components": [ "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072435": { "compartment": "compartment_70101", "id": "reaction_10072435", "reactome": "R-BTA-5624125", "name": "Formation of the BBSome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072245", "species_10072229", "species_10072257", "species_10072241", "species_10072253", "species_10072237", "species_10072249", "species_10072233" ], "products": [ "species_10072259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006505", "ENSBTAT00000026844", "ENSBTAT00000064380", "ENSBTAT00000014216", "ENSBTAT00000042964", "ENSBTAT00000010013", "ENSBTAT00000008587", "ENSBTAT00000032389", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072453": { "compartment": "compartment_876", "id": "reaction_10072453", "reactome": "R-BTA-5624126", "name": "ARL6:GTP and the BBSome bind ciliary cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072259", "species_10072449", "species_10072441" ], "products": [ "species_10072451" ], "modifiers": [], "additional_components": [ "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10057569": { "compartment": "compartment_876", "id": "reaction_10057569", "reactome": "R-BTA-1296127", "name": "Activation of voltage gated Potassium channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057566", "catalyst" ] ], "additional_components": [ "Q4PJK1", "ENSBTAT00000024576", "A2VDT0", "ENSBTAT00000019888", "E1B7K3", "ENSBTAT00000064709", "F1MLD6", "ENSBTAT00000022142", "F1MTJ1", "ENSBTAT00000009938", "F1N0E8", "ENSBTAT00000010960", "G3N1T8", "ENSBTAT00000065475", "F1MKB0", "ENSBTAT00000020543", "E1B9N0", "ENSBTAT00000021458", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1MFH2", "ENSBTAT00000086274", "A0A3Q1MPE6", "ENSBTAT00000074581", "E1BDC5", "ENSBTAT00000039169", "F1ML52", "ENSBTAT00000022193", "F1MJA9", "ENSBTAT00000018162", "E1BCM0", "ENSBTAT00000004406", "F1MC54", "ENSBTAT00000046307", "F1MP51", "ENSBTAT00000015122", "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "F1MPV7", "ENSBTAT00000010214", "E1BKI8", "ENSBTAT00000011681", "F1N553", "ENSBTAT00000007132", "A0A3Q1M6H7", "ENSBTAT00000071160", "A4FV89", "ENSBTAT00000028357", "F1MXZ4", "ENSBTAT00000011219", "E1BII8", "ENSBTAT00000023770", "E1B760", "ENSBTAT00000025668", "E1BLH0", "ENSBTAT00000005335", "F1MDM5", "ENSBTAT00000017003", "A0A3Q1LSF6", "ENSBTAT00000067149", "E1BMA2", "ENSBTAT00000022102" ] }, "reaction_10057365": { "compartment": "compartment_876", "id": "reaction_10057365", "reactome": "R-BTA-1296039", "name": "Activation of Ca2+ activated Potassium channels with small conductance", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057362", "catalyst" ] ], "additional_components": [ "E1BGY2", "ENSBTAT00000011376", "F1N467", "ENSBTAT00000014706" ] }, "reaction_10057665": { "compartment": "compartment_876", "id": "reaction_10057665", "reactome": "R-BTA-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057662", "catalyst" ] ], "additional_components": [ "F1MW24", "ENSBTAT00000020046" ] }, "reaction_10057656": { "compartment": "compartment_876", "id": "reaction_10057656", "reactome": "R-BTA-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057653", "catalyst" ] ], "additional_components": [ "A0A3Q1MT89", "ENSBTAT00000075452", "G3N1D1", "ENSBTAT00000063834" ] }, "reaction_10057682": { "compartment": "compartment_876", "id": "reaction_10057682", "reactome": "R-BTA-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057679", "catalyst" ] ], "additional_components": [ "Q8HZT2", "ENSBTAT00000013646", "E1BEH1", "ENSBTAT00000030656" ] }, "reaction_10057616": { "compartment": "compartment_876", "id": "reaction_10057616", "reactome": "R-BTA-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057613", "catalyst" ] ], "additional_components": [ "G3N1Q6", "ENSBTAT00000065420" ] }, "reaction_10090498": { "compartment": "compartment_70101", "id": "reaction_10090498", "reactome": "R-BTA-9027043", "name": "CYPs hydroxylate DHA to 14(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_9024011" ], "products": [ "species_29356", "species_29366", "species_9027049" ], "modifiers": [ [ "species_10090495", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "Q2KJJ2", "ENSBTAT00000000869", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10084300": { "compartment": "compartment_876", "id": "reaction_10084300", "reactome": "R-BTA-8854628", "name": "MYLIP dimer ubiquitinates VLDLR on Lys-839", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084266" ], "products": [ "species_10084295" ], "modifiers": [ [ "species_10084297", "catalyst" ], [ "species_10045642", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071362", "ENSBTAT00000071362", "A6QQD1", "ENSBTAT00000005377", "ENSBTAT00000071739" ] }, "reaction_10083113": { "compartment": "compartment_70101", "id": "reaction_10083113", "reactome": "R-BTA-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10083110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026745" ] }, "reaction_10085994": { "compartment": "compartment_161320", "id": "reaction_10085994", "reactome": "R-BTA-8876472", "name": "NPC2 binds CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085990", "species_8848047" ], "products": [ "species_10085992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029271", "species_193840", "P79345", "ENSBTAT00000029271" ] }, "reaction_10086026": { "compartment": "compartment_12045", "id": "reaction_10086026", "reactome": "R-BTA-8876696", "name": "SOAT1,2 transfer acyl group to CHOL forming CHEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384", "species_1500578" ], "products": [ "species_8876704", "species_76194" ], "modifiers": [ [ "species_10086023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033962" ] }, "reaction_10086557": { "compartment": "compartment_70101", "id": "reaction_10086557", "reactome": "R-BTA-8937442", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10086554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056670" ] }, "reaction_10086002": { "compartment": "compartment_161320", "id": "reaction_10086002", "reactome": "R-BTA-8876484", "name": "NPC2 transfers CHOL to NPC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085998", "species_10085992" ], "products": [ "species_10085990", "species_10086000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085568", "species_193840", "P79345", "ENSBTAT00000029271", "ENSBTAT00000029271", "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840" ] }, "reaction_10086004": { "compartment": "compartment_12045", "id": "reaction_10086004", "reactome": "R-BTA-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086000" ], "products": [ "species_193384", "species_10085998" ], "modifiers": [], "additional_components": [ "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840", "ENSBTAT00000085568" ] }, "reaction_10044020": { "compartment": "compartment_876", "id": "reaction_10044020", "reactome": "R-BTA-210282", "name": "Interaction of GPVI and FceRI gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037447", "species_10037453" ], "products": [ "species_10037455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426" ] }, "reaction_10049300": { "compartment": "compartment_70101", "id": "reaction_10049300", "reactome": "R-BTA-432295", "name": "GPVI binds Fyn and Lyn", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037463", "species_10037459", "species_10037455" ], "products": [ "species_10037465" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000015730", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10040521": { "compartment": "compartment_7660", "id": "reaction_10040521", "reactome": "R-BTA-187545", "name": "Association of Cks1 with SCF(Skp2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040517", "species_10040513" ], "products": [ "species_10040519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033975", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040542": { "compartment": "compartment_7660", "id": "reaction_10040542", "reactome": "R-BTA-187575", "name": "Ubiquitination of phospho-p27/p21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10040537" ], "products": [ "species_10040539" ], "modifiers": [ [ "species_10040537", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040576": { "compartment": "compartment_13231", "id": "reaction_10040576", "reactome": "R-BTA-187828", "name": "Translocation of p21 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040572" ], "products": [ "species_10040574" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011001", "ENSBTAT00000011001" ] }, "reaction_10040503": { "compartment": "compartment_13231", "id": "reaction_10040503", "reactome": "R-BTA-187506", "name": "Translocation of p27 to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499" ], "products": [ "species_10040501" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297" ] }, "reaction_10033512": { "compartment": "compartment_7660", "id": "reaction_10033512", "reactome": "R-BTA-69299", "name": "Cdt1 associates with geminin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033414", "species_10033508" ], "products": [ "species_10033510" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067336", "ENSBTAT00000023040", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336" ] }, "reaction_10033466": { "compartment": "compartment_7660", "id": "reaction_10033466", "reactome": "R-BTA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033462", "species_68419" ], "products": [ "species_10033464" ], "modifiers": [], "additional_components": [ "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798", "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798" ] }, "reaction_10087385": { "compartment": "compartment_70101", "id": "reaction_10087385", "reactome": "R-BTA-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087381", "species_10040351" ], "products": [ "species_10087383" ], "modifiers": [ [ "species_10040353", "inhibitor" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10056616": { "compartment": "compartment_7660", "id": "reaction_10056616", "reactome": "R-BTA-1226095", "name": "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056608" ], "products": [ "species_10056566", "species_113582", "species_10056614" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000015333", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057816": { "compartment": "compartment_7660", "id": "reaction_10057816", "reactome": "R-BTA-1363328", "name": "Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040519", "species_10056564" ], "products": [ "species_10057814" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10056602": { "compartment": "compartment_7660", "id": "reaction_10056602", "reactome": "R-BTA-1226094", "name": "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056559" ], "products": [ "species_113582", "species_10056566", "species_10056564" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000084739", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057821": { "compartment": "compartment_7660", "id": "reaction_10057821", "reactome": "R-BTA-1363331", "name": "Ubiquitination of p130 (RBL2) by SCF (Skp2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057814", "species_10036828" ], "products": [ "species_10040519", "species_10057818" ], "modifiers": [ [ "species_10057814", "catalyst" ] ], "additional_components": [ "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1M1Y7", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10087487": { "compartment": "compartment_70101", "id": "reaction_10087487", "reactome": "R-BTA-8942607", "name": "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087392" ], "products": [ "species_29370", "species_10087465" ], "modifiers": [ [ "species_10087484", "catalyst" ] ], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001" ] }, "reaction_10087503": { "compartment": "compartment_13231", "id": "reaction_10087503", "reactome": "R-BTA-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087491" ], "products": [ "species_10087501" ], "modifiers": [], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10087394": { "compartment": "compartment_70101", "id": "reaction_10087394", "reactome": "R-BTA-8941915", "name": "Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087383", "species_10087390" ], "products": [ "species_10087392" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277" ] }, "reaction_10065794": { "compartment": "compartment_70101", "id": "reaction_10065794", "reactome": "R-BTA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065782", "species_29356" ], "products": [ "species_29372", "species_10065792" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562", "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10035745": { "compartment": "compartment_13231", "id": "reaction_10035745", "reactome": "R-BTA-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035737" ], "products": [ "species_10035743" ], "modifiers": [], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10035747": { "compartment": "compartment_13231", "id": "reaction_10035747", "reactome": "R-BTA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035731" ], "products": [ "species_10035739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023277", "ENSBTAT00000023277" ] }, "reaction_10074692": { "compartment": "compartment_7660", "id": "reaction_10074692", "reactome": "R-BTA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074688" ], "products": [ "species_10074690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10074695": { "compartment": "compartment_7660", "id": "reaction_10074695", "reactome": "R-BTA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074690" ], "products": [ "species_113582", "species_10033532" ], "modifiers": [ [ "species_10074690", "catalyst" ] ], "additional_components": [ "F6R5E4", "ENSBTAT00000006518", "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10051465": { "compartment": "compartment_7660", "id": "reaction_10051465", "reactome": "R-BTA-606349", "name": "Mis18 complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051445", "species_10051395" ], "products": [ "species_10051453" ], "modifiers": [], "additional_components": [ "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256" ] }, "reaction_10051451": { "compartment": "compartment_7660", "id": "reaction_10051451", "reactome": "R-BTA-606287", "name": "RSF complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051447", "species_10051335" ], "products": [ "species_10051431", "species_10051445", "species_10051449" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10051461": { "compartment": "compartment_7660", "id": "reaction_10051461", "reactome": "R-BTA-606289", "name": "New CENPA-containing nucleosomes are deposited at the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035218", "species_10051459", "species_10035105" ], "products": [ "species_10051447" ], "modifiers": [], "additional_components": [ "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10051463": { "compartment": "compartment_7660", "id": "reaction_10051463", "reactome": "R-BTA-606326", "name": "HJURP:CENPA complex localizes to the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051457", "species_10051453" ], "products": [ "species_10051459" ], "modifiers": [], "additional_components": [ "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10058792": { "compartment": "compartment_70101", "id": "reaction_10058792", "reactome": "R-BTA-1475436", "name": "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057070": { "compartment": "compartment_70101", "id": "reaction_10057070", "reactome": "R-BTA-1247668", "name": "Hemoglobin A binds O2, releasing H+ and CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057060", "species_29368" ], "products": [ "species_10057046", "species_70106", "species_113528" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323" ] }, "reaction_10063560": { "compartment": "compartment_7660", "id": "reaction_10063560", "reactome": "R-BTA-2065539", "name": "SREBP1A,1C,2:Importin beta-1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043501", "species_10060344" ], "products": [ "species_10063558", "species_10060342" ], "modifiers": [], "additional_components": [ "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063562": { "compartment": "compartment_70101", "id": "reaction_10063562", "reactome": "R-BTA-2065549", "name": "SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060328" ], "products": [ "species_10060330" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10060346": { "compartment": "compartment_70101", "id": "reaction_10060346", "reactome": "R-BTA-1655831", "name": "SREBP1A,1C,2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060332" ], "products": [ "species_10060344" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063564": { "compartment": "compartment_70101", "id": "reaction_10063564", "reactome": "R-BTA-2065550", "name": "SREBP1A,1C,2 binds Importin beta-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10060330" ], "products": [ "species_10060332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10090604": { "compartment": "compartment_17951", "id": "reaction_10090604", "reactome": "R-BTA-9033520", "name": "TYSND1 cleaves TYSND1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_10090597" ], "products": [ "species_10090599", "species_10090601" ], "modifiers": [ [ "species_10090597", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816" ] }, "reaction_10037293": { "compartment": "compartment_70101", "id": "reaction_10037293", "reactome": "R-BTA-114392", "name": "Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037287" ], "products": [ "species_10037229", "species_10037291" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10090504": { "compartment": "compartment_70101", "id": "reaction_10090504", "reactome": "R-BTA-9027532", "name": "PTGS2 dimer oxidises DHA to 13-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027547" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090506": { "compartment": "compartment_70101", "id": "reaction_10090506", "reactome": "R-BTA-9027607", "name": "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9027614" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090508": { "compartment": "compartment_70101", "id": "reaction_10090508", "reactome": "R-BTA-9027627", "name": "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027622" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090510": { "compartment": "compartment_70101", "id": "reaction_10090510", "reactome": "R-BTA-9028255", "name": "PTGS2 dimer oxidises EPA to PGH3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9028280" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10075037": { "compartment": "compartment_7660", "id": "reaction_10075037", "reactome": "R-BTA-5685953", "name": "SIRT6 deacetylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075030", "species_427523" ], "products": [ "species_427497", "species_427498", "species_10074778" ], "modifiers": [ [ "species_10075034", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "ENSBTAT00000026521" ] }, "reaction_10074798": { "compartment": "compartment_7660", "id": "reaction_10074798", "reactome": "R-BTA-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074795" ], "products": [ "species_113582", "species_10074789" ], "modifiers": [ [ "species_10074795", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076339": { "compartment": "compartment_7660", "id": "reaction_10076339", "reactome": "R-BTA-5693608", "name": "Initial resection of double-strand break ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076336" ], "products": [ "species_30555", "species_10075051" ], "modifiers": [ [ "species_10076336", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498" ] }, "reaction_10060476": { "compartment": "compartment_12045", "id": "reaction_10060476", "reactome": "R-BTA-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10060456", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047316" ] }, "reaction_10083369": { "compartment": "compartment_876", "id": "reaction_10083369", "reactome": "R-BTA-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10083366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015375" ] }, "reaction_10083211": { "compartment": "compartment_12045", "id": "reaction_10083211", "reactome": "R-BTA-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6814253" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10083208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084401" ] }, "reaction_10082931": { "compartment": "compartment_172574", "id": "reaction_10082931", "reactome": "R-BTA-6810392", "name": "TMEM55B translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082927" ], "products": [ "species_10082929" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003561", "ENSBTAT00000003561" ] }, "reaction_10083092": { "compartment": "compartment_7660", "id": "reaction_10083092", "reactome": "R-BTA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10083089", "catalyst" ] ], "additional_components": [ "F1MHT2", "ENSBTAT00000008517", "F1MHR4", "ENSBTAT00000024007" ] }, "reaction_10082934": { "compartment": "compartment_7660", "id": "reaction_10082934", "reactome": "R-BTA-6810410", "name": "PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_6810412" ], "products": [ "species_6810408", "species_113550" ], "modifiers": [ [ "species_10082929", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003561" ] }, "reaction_10060569": { "compartment": "compartment_876", "id": "reaction_10060569", "reactome": "R-BTA-1676109", "name": "PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060566", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "E1B8D1", "ENSBTAT00000043102", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MBU9", "ENSBTAT00000017388", "species_113527" ] }, "reaction_10060473": { "compartment": "compartment_876", "id": "reaction_10060473", "reactome": "R-BTA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082136": { "compartment": "compartment_70101", "id": "reaction_10082136", "reactome": "R-BTA-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10082128" ], "products": [ "species_10082134" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000050192", "F1ME94", "ENSBTAT00000050192", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060600": { "compartment": "compartment_876", "id": "reaction_10060600", "reactome": "R-BTA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10085784": { "compartment": "compartment_171062", "id": "reaction_10085784", "reactome": "R-BTA-8871376", "name": "p-Y281,292-RUFY1 binds PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085767", "species_1806200" ], "products": [ "species_10085782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "species_5693050", "F6R352", "ENSBTAT00000000317" ] }, "reaction_10060572": { "compartment": "compartment_876", "id": "reaction_10060572", "reactome": "R-BTA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060595": { "compartment": "compartment_876", "id": "reaction_10060595", "reactome": "R-BTA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10060592", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BLB5", "ENSBTAT00000022635" ] }, "reaction_10085780": { "compartment": "compartment_70101", "id": "reaction_10085780", "reactome": "R-BTA-8871373", "name": "BMX phosphorylates RUFY1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10085777" ], "products": [ "species_29370", "species_10085773" ], "modifiers": [ [ "species_10044855", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317", "ENSBTAT00000000488" ] }, "reaction_10060535": { "compartment": "compartment_876", "id": "reaction_10060535", "reactome": "R-BTA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10082152": { "compartment": "compartment_876", "id": "reaction_10082152", "reactome": "R-BTA-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10082155": { "compartment": "compartment_876", "id": "reaction_10082155", "reactome": "R-BTA-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10060429": { "compartment": "compartment_876", "id": "reaction_10060429", "reactome": "R-BTA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060461": { "compartment": "compartment_876", "id": "reaction_10060461", "reactome": "R-BTA-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10085775": { "compartment": "compartment_70101", "id": "reaction_10085775", "reactome": "R-BTA-8871370", "name": "p-Y281,292-RUFY1 translocates from cytosol to early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085773" ], "products": [ "species_10085767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317" ] }, "reaction_10060590": { "compartment": "compartment_876", "id": "reaction_10060590", "reactome": "R-BTA-1676164", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_202247" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10085697": { "compartment": "compartment_876", "id": "reaction_10085697", "reactome": "R-BTA-8870489", "name": "PLEKHA4,(5,6) bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_10085693" ], "products": [ "species_10085695" ], "modifiers": [], "additional_components": [ "E1B7V8", "ENSBTAT00000061135", "E1B7V8", "ENSBTAT00000061135", "species_5693050" ] }, "reaction_10060579": { "compartment": "compartment_876", "id": "reaction_10060579", "reactome": "R-BTA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060576", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082147": { "compartment": "compartment_70101", "id": "reaction_10082147", "reactome": "R-BTA-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10060526" ], "products": [ "species_10082145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000069408", "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060514": { "compartment": "compartment_876", "id": "reaction_10060514", "reactome": "R-BTA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10060511", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10060550": { "compartment": "compartment_876", "id": "reaction_10060550", "reactome": "R-BTA-1676048", "name": "PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060547", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10083800": { "compartment": "compartment_70101", "id": "reaction_10083800", "reactome": "R-BTA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10083797", "catalyst" ] ], "additional_components": [ "species_179838", "species_1806238", "species_6810412", "species_5693050", "species_1806205", "species_1806259", "ENSBTAT00000029059" ] }, "reaction_10060588": { "compartment": "compartment_171062", "id": "reaction_10060588", "reactome": "R-BTA-1676162", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806238" ], "products": [ "species_29372", "species_1806200" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10060558": { "compartment": "compartment_171062", "id": "reaction_10060558", "reactome": "R-BTA-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806205" ], "products": [ "species_29372", "species_1806259" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060574": { "compartment": "compartment_171062", "id": "reaction_10060574", "reactome": "R-BTA-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_29372", "species_1806199" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060501": { "compartment": "compartment_171062", "id": "reaction_10060501", "reactome": "R-BTA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060518": { "compartment": "compartment_171062", "id": "reaction_10060518", "reactome": "R-BTA-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_1806180", "species_29370" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060614": { "compartment": "compartment_171062", "id": "reaction_10060614", "reactome": "R-BTA-1676206", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806180", "species_113592" ], "products": [ "species_29370", "species_1806238" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060611": { "compartment": "compartment_20699", "id": "reaction_10060611", "reactome": "R-BTA-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060608", "catalyst" ] ], "additional_components": [ "A0A3Q1MHQ7", "ENSBTAT00000081928" ] }, "reaction_10060483": { "compartment": "compartment_20699", "id": "reaction_10060483", "reactome": "R-BTA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001784" ] }, "reaction_10060498": { "compartment": "compartment_20699", "id": "reaction_10060498", "reactome": "R-BTA-1675928", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806217" ], "products": [ "species_1806230", "species_29370" ], "modifiers": [ [ "species_10060495", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "E1B8D1", "ENSBTAT00000043102" ] }, "reaction_10060597": { "compartment": "compartment_20699", "id": "reaction_10060597", "reactome": "R-BTA-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060516": { "compartment": "compartment_20699", "id": "reaction_10060516", "reactome": "R-BTA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10085843": { "compartment": "compartment_437051", "id": "reaction_10085843", "reactome": "R-BTA-8874470", "name": "TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8874484" ], "products": [ "species_8874460" ], "modifiers": [ [ "species_10085840", "catalyst" ] ], "additional_components": [ "species_179838", "species_6810412", "species_6810412", "species_179838", "A0A3Q1LVF0", "ENSBTAT00000072298" ] }, "reaction_10040152": { "compartment": "compartment_70101", "id": "reaction_10040152", "reactome": "R-BTA-176664", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176575", "species_158471" ], "products": [ "species_176501", "species_158466" ], "modifiers": [ [ "species_10040149", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040120": { "compartment": "compartment_70101", "id": "reaction_10040120", "reactome": "R-BTA-176588", "name": "lithocholate + PAPS => lithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_158471" ], "products": [ "species_176555", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040122": { "compartment": "compartment_70101", "id": "reaction_10040122", "reactome": "R-BTA-176604", "name": "taurolithocholate + PAPS => taurolithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176565", "species_158471" ], "products": [ "species_176483", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040157": { "compartment": "compartment_70101", "id": "reaction_10040157", "reactome": "R-BTA-176669", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176566" ], "products": [ "species_176500", "species_158466" ], "modifiers": [ [ "species_10040154", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388" ] }, "reaction_10076799": { "compartment": "compartment_70101", "id": "reaction_10076799", "reactome": "R-BTA-5695964", "name": "ABHD14B hydrolyses PNPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695960", "species_29356" ], "products": [ "species_5695950", "species_76179" ], "modifiers": [ [ "species_10076796", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024782" ] }, "reaction_10038320": { "compartment": "compartment_70101", "id": "reaction_10038320", "reactome": "R-BTA-158860", "name": "SULT1A1 dimer sulfonates NHABP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158847", "species_158471" ], "products": [ "species_158859", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040112": { "compartment": "compartment_70101", "id": "reaction_10040112", "reactome": "R-BTA-176517", "name": "SULTs transfer (SO4)2- group to PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_158471" ], "products": [ "species_176665", "species_158466" ], "modifiers": [ [ "species_10040109", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040147": { "compartment": "compartment_70101", "id": "reaction_10040147", "reactome": "R-BTA-176646", "name": "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695950", "species_158471" ], "products": [ "species_176600", "species_158466" ], "modifiers": [ [ "species_10040144", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "P50227", "ENSBTAT00000011388" ] }, "reaction_10040115": { "compartment": "compartment_70101", "id": "reaction_10040115", "reactome": "R-BTA-176521", "name": "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_158471" ], "products": [ "species_176492", "species_158466" ], "modifiers": [ [ "species_10040075", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040117": { "compartment": "compartment_70101", "id": "reaction_10040117", "reactome": "R-BTA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176667", "species_158471" ], "products": [ "species_176564", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038231": { "compartment": "compartment_70101", "id": "reaction_10038231", "reactome": "R-BTA-158468", "name": "SULT1A1 dimer sulfonates PARA to PARA-SO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158469", "species_158471" ], "products": [ "species_158472", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088617": { "compartment": "compartment_17963", "id": "reaction_10088617", "reactome": "R-BTA-8954262", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10088606" ], "products": [ "species_742343", "species_10088610" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043559", "ENSBTAT00000043559", "ENSBTAT00000000502" ] }, "reaction_10040136": { "compartment": "compartment_70101", "id": "reaction_10040136", "reactome": "R-BTA-176631", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176626" ], "products": [ "species_176496", "species_158466" ], "modifiers": [ [ "species_10040133", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040107": { "compartment": "compartment_70101", "id": "reaction_10040107", "reactome": "R-BTA-176494", "name": "SULTs transfer (SO4)2- group to 27HCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176617", "species_158471" ], "products": [ "species_176502", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10038318": { "compartment": "compartment_70101", "id": "reaction_10038318", "reactome": "R-BTA-158849", "name": "Phenol can form a sulfate conjugate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158858", "species_158471" ], "products": [ "species_158466", "species_158850" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040129": { "compartment": "compartment_70101", "id": "reaction_10040129", "reactome": "R-BTA-176606", "name": "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_158466" ], "products": [ "species_29372", "species_76577" ], "modifiers": [ [ "species_10040126", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005311" ] }, "reaction_10040131": { "compartment": "compartment_70101", "id": "reaction_10040131", "reactome": "R-BTA-176609", "name": "cholesterol + PAPS => cholesterol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_158471" ], "products": [ "species_176618", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10040098": { "compartment": "compartment_70101", "id": "reaction_10040098", "reactome": "R-BTA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176486" ], "products": [ "species_176519", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038340": { "compartment": "compartment_70101", "id": "reaction_10038340", "reactome": "R-BTA-159358", "name": "SULT1A3,4 dimers sulfate DA to DAOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_159362" ], "products": [ "species_159352", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088580": { "compartment": "compartment_17963", "id": "reaction_10088580", "reactome": "R-BTA-8953499", "name": "IMPAD1 hydrolyses PAP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742343", "species_2022884" ], "products": [ "species_8851226", "species_8953493" ], "modifiers": [ [ "species_10088577", "catalyst" ], [ "species_8953505", "inhibitor" ] ], "additional_components": [ "species_29926", "A0A452DIR7", "ENSBTAT00000020766" ] }, "reaction_10050342": { "compartment": "compartment_70101", "id": "reaction_10050342", "reactome": "R-BTA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10050336" ], "products": [ "species_10050340" ], "modifiers": [], "additional_components": [ "A0A3Q1M8I4", "ENSBTAT00000075547", "A0A3Q1M8I4", "ENSBTAT00000075547" ] }, "reaction_10082923": { "compartment": "compartment_7660", "id": "reaction_10082923", "reactome": "R-BTA-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_10069400" ], "products": [ "species_10082921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "species_1806259" ] }, "reaction_10086155": { "compartment": "compartment_7660", "id": "reaction_10086155", "reactome": "R-BTA-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086151", "species_10053086" ], "products": [ "species_10086153" ], "modifiers": [], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10083072": { "compartment": "compartment_7660", "id": "reaction_10083072", "reactome": "R-BTA-6811479", "name": "ING2 recruits EP300 to TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10053052", "species_10069400" ], "products": [ "species_10083070" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021556", "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10083077": { "compartment": "compartment_7660", "id": "reaction_10083077", "reactome": "R-BTA-6811508", "name": "ING2-bound EP300 acetylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10083070" ], "products": [ "species_2485002", "species_10083074" ], "modifiers": [ [ "species_10083070", "catalyst" ], [ "species_6810408", "catalyst" ] ], "additional_components": [ "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10090593": { "compartment": "compartment_70101", "id": "reaction_10090593", "reactome": "R-BTA-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090579", "species_10090589" ], "products": [ "species_10090591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022338", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "Q08DL6", "ENSBTAT00000022338" ] }, "reaction_10090770": { "compartment": "compartment_70101", "id": "reaction_10090770", "reactome": "R-BTA-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090766", "species_10090732" ], "products": [ "species_10090768" ], "modifiers": [], "additional_components": [ "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885", "ENSBTAT00000009921", "Q3SZD1", "ENSBTAT00000009921", "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885" ] }, "reaction_10039049": { "compartment": "compartment_5460", "id": "reaction_10039049", "reactome": "R-BTA-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10039037" ], "products": [ "species_10039039" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039044": { "compartment": "compartment_5460", "id": "reaction_10039044", "reactome": "R-BTA-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039039" ], "products": [ "species_10039041", "species_113521" ], "modifiers": [ [ "species_10039039", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039047": { "compartment": "compartment_5460", "id": "reaction_10039047", "reactome": "R-BTA-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039041", "species_163953" ], "products": [ "species_113529", "species_113593", "species_10039037" ], "modifiers": [ [ "species_10039041", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592" ] }, "reaction_10035417": { "compartment": "compartment_5460", "id": "reaction_10035417", "reactome": "R-BTA-74181", "name": "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_73871" ], "products": [ "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10035374": { "compartment": "compartment_5460", "id": "reaction_10035374", "reactome": "R-BTA-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_73911" ], "products": [ "species_113529", "species_73909", "species_29362" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10035415": { "compartment": "compartment_5460", "id": "reaction_10035415", "reactome": "R-BTA-74177", "name": "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_73909" ], "products": [ "species_73871", "species_113536" ], "modifiers": [ [ "species_10035412", "catalyst" ] ], "additional_components": [ "A0A3Q1LIX4", "ENSBTAT00000077723" ] }, "reaction_10065944": { "compartment": "compartment_2514888", "id": "reaction_10065944", "reactome": "R-BTA-2632521", "name": "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035617" ], "products": [ "species_10065942", "species_2466098" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10035596": { "compartment": "compartment_2514888", "id": "reaction_10035596", "reactome": "R-BTA-74885", "name": "GUCYs converts GTP to cGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438" ], "products": [ "species_111294", "species_30991" ], "modifiers": [ [ "species_10035583", "catalyst" ], [ "species_10035592", "catalyst" ], [ "species_10035594", "inhibitor" ], [ "species_10035590", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000011564", "ENSBTAT00000087322", "P46065", "ENSBTAT00000087322", "species_74016", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10065808": { "compartment": "compartment_70101", "id": "reaction_10065808", "reactome": "R-BTA-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065796", "species_2534019" ], "products": [ "species_10065799", "species_76194" ], "modifiers": [ [ "species_10065805", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023990", "ENSBTAT00000023990", "Q9N181", "ENSBTAT00000050460", "F1MZK0", "ENSBTAT00000007950" ] }, "reaction_10035619": { "compartment": "compartment_2514888", "id": "reaction_10035619", "reactome": "R-BTA-74948", "name": "PP2A dephosphorylates p-RHO to RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035601" ], "products": [ "species_29372", "species_2565923" ], "modifiers": [ [ "species_10035607", "catalyst" ], [ "species_74016", "catalyst" ], [ "species_10035617", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730", "species_29926", "F1MBQ1", "ENSBTAT00000068795", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10065940": { "compartment": "compartment_70101", "id": "reaction_10065940", "reactome": "R-BTA-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035588", "species_74016" ], "products": [ "species_10035590" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087322", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10078600": { "compartment": "compartment_876", "id": "reaction_10078600", "reactome": "R-BTA-6797974", "name": "LRRTMs bind NRXNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078596", "species_10078418" ], "products": [ "species_10078598" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078488": { "compartment": "compartment_70101", "id": "reaction_10078488", "reactome": "R-BTA-6797553", "name": "Protein 4.1 binds CASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078484", "species_10071423" ], "products": [ "species_10078486" ], "modifiers": [], "additional_components": [ "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "ENSBTAT00000071329", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078522": { "compartment": "compartment_876", "id": "reaction_10078522", "reactome": "R-BTA-6797568", "name": "NRXNs bind CASK:Protein 4.1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078486", "species_10078444" ], "products": [ "species_10078520" ], "modifiers": [], "additional_components": [ "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078446": { "compartment": "compartment_876", "id": "reaction_10078446", "reactome": "R-BTA-6794346", "name": "NRXNs bind NLGNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078418", "species_10078442" ], "products": [ "species_10078444" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078464": { "compartment": "compartment_876", "id": "reaction_10078464", "reactome": "R-BTA-6794347", "name": "Homer1,2,3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078458", "species_10078456" ], "products": [ "species_10078462" ], "modifiers": [], "additional_components": [ "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078466": { "compartment": "compartment_876", "id": "reaction_10078466", "reactome": "R-BTA-6794355", "name": "Homer1,2,3 binds mGluR1a,5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045110", "species_10078456" ], "products": [ "species_10078458" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078518": { "compartment": "compartment_876", "id": "reaction_10078518", "reactome": "R-BTA-6797554", "name": "ABP1 binds SHANK proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078514", "species_10043423" ], "products": [ "species_10078516" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330", "ENSBTAT00000023325", "A0A452DIT4", "ENSBTAT00000023325", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330" ] }, "reaction_10046648": { "compartment": "compartment_70101", "id": "reaction_10046648", "reactome": "R-BTA-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046644" ], "products": [ "species_10046646", "species_29420" ], "modifiers": [ [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ] ], "additional_components": [ "species_29420", "P62833", "ENSBTAT00000068678", "P62833", "ENSBTAT00000068678", "species_29438", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046623": { "compartment": "compartment_876", "id": "reaction_10046623", "reactome": "R-BTA-381608", "name": "cAMP activates EPAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044624", "species_30389" ], "products": [ "species_10044626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061074", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046642": { "compartment": "compartment_876", "id": "reaction_10046642", "reactome": "R-BTA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046640" ], "products": [ "species_10046640" ], "modifiers": [], "additional_components": [ "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162", "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162" ] }, "reaction_10046630": { "compartment": "compartment_876", "id": "reaction_10046630", "reactome": "R-BTA-381668", "name": "cAMP activates EPAC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044630", "species_30389" ], "products": [ "species_10044632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085533", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10043885": { "compartment": "compartment_876", "id": "reaction_10043885", "reactome": "R-BTA-209738", "name": "VD3 binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209767", "species_10043881" ], "products": [ "species_10043883" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870" ] }, "reaction_10043903": { "compartment": "compartment_70101", "id": "reaction_10043903", "reactome": "R-BTA-209760", "name": "Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043895" ], "products": [ "species_10043901" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "A0A3Q1LQ02", "ENSBTAT00000075079", "F1MKV7", "ENSBTAT00000039417", "species_209804" ] }, "reaction_10088926": { "compartment": "compartment_984", "id": "reaction_10088926", "reactome": "R-BTA-8963851", "name": "VD3 dissociates from GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043883" ], "products": [ "species_209767", "species_10043881" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870", "ENSBTAT00000075079" ] }, "reaction_10043984": { "compartment": "compartment_984", "id": "reaction_10043984", "reactome": "R-BTA-209944", "name": "25(OH)D binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209906", "species_10043881" ], "products": [ "species_10043982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10088928": { "compartment": "compartment_161320", "id": "reaction_10088928", "reactome": "R-BTA-8963864", "name": "CUBN dissociates from 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044728" ], "products": [ "species_350136", "species_10043899" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "species_209804", "ENSBTAT00000039417" ] }, "reaction_10044739": { "compartment": "compartment_876", "id": "reaction_10044739", "reactome": "R-BTA-350168", "name": "LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044732" ], "products": [ "species_10043895" ], "modifiers": [ [ "species_10044736", "catalyst" ] ], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000005988" ] }, "reaction_10044741": { "compartment": "compartment_984", "id": "reaction_10044741", "reactome": "R-BTA-350186", "name": "CUBN binds GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043982", "species_10044730" ], "products": [ "species_10044732" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000039417", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10043910": { "compartment": "compartment_70616", "id": "reaction_10043910", "reactome": "R-BTA-209765", "name": "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_209800", "species_29368", "species_29364" ], "products": [ "species_29356", "species_350159", "species_29366" ], "modifiers": [ [ "species_10043907", "catalyst" ], [ "species_29532", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10040922": { "compartment": "compartment_70101", "id": "reaction_10040922", "reactome": "R-BTA-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191265" ], "products": [ "species_111294", "species_191269", "species_29366" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10041664": { "compartment": "compartment_70101", "id": "reaction_10041664", "reactome": "R-BTA-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_195691", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_195655" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10041728": { "compartment": "compartment_70101", "id": "reaction_10041728", "reactome": "R-BTA-196417", "name": "Reduction of desmosterol to cholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_196420", "species_29364" ], "products": [ "species_193384", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041671": { "compartment": "compartment_12045", "id": "reaction_10041671", "reactome": "R-BTA-195690", "name": "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194691" ], "products": [ "species_195691" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10040892": { "compartment": "compartment_70101", "id": "reaction_10040892", "reactome": "R-BTA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10040924": { "compartment": "compartment_70101", "id": "reaction_10040924", "reactome": "R-BTA-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_111294", "species_191265" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10040895": { "compartment": "compartment_70101", "id": "reaction_10040895", "reactome": "R-BTA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10041502": { "compartment": "compartment_70101", "id": "reaction_10041502", "reactome": "R-BTA-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194657", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194661", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10040913": { "compartment": "compartment_70101", "id": "reaction_10040913", "reactome": "R-BTA-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10040910", "catalyst" ] ], "additional_components": [ "A0A140T853", "ENSBTAT00000005323", "species_29926" ] }, "reaction_10040881": { "compartment": "compartment_70101", "id": "reaction_10040881", "reactome": "R-BTA-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_191269", "species_29364" ], "products": [ "species_191309", "species_29356", "species_29366" ], "modifiers": [ [ "species_10040878", "catalyst" ] ], "additional_components": [ "A5D9A8", "ENSBTAT00000007228", "species_113596" ] }, "reaction_10088019": { "compartment": "compartment_70101", "id": "reaction_10088019", "reactome": "R-BTA-8952137", "name": "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_191265" ], "products": [ "species_8952135", "species_29372" ], "modifiers": [ [ "species_10088016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014674" ] }, "reaction_10041493": { "compartment": "compartment_13231", "id": "reaction_10041493", "reactome": "R-BTA-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194725", "species_194688" ], "products": [ "species_194668", "species_194704" ], "modifiers": [ [ "species_10041490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011125" ] }, "reaction_10083496": { "compartment": "compartment_70101", "id": "reaction_10083496", "reactome": "R-BTA-8848215", "name": "ACAT2 condenses 2 Ac-CoA to form ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_191293", "species_29356", "species_76194" ], "modifiers": [ [ "species_10083493", "catalyst" ] ], "additional_components": [ "A0A3Q1MLP4", "ENSBTAT00000012548" ] }, "reaction_10040904": { "compartment": "compartment_70101", "id": "reaction_10040904", "reactome": "R-BTA-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191374", "species_70106", "species_29364" ], "products": [ "species_29366", "species_76194", "species_191424" ], "modifiers": [ [ "species_10040901", "catalyst" ] ], "additional_components": [ "A7Z064", "ENSBTAT00000010315" ] }, "reaction_10041484": { "compartment": "compartment_70101", "id": "reaction_10041484", "reactome": "R-BTA-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194667", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10041486": { "compartment": "compartment_70101", "id": "reaction_10041486", "reactome": "R-BTA-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_194723" ], "products": [ "species_29356", "species_29366", "species_194657" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10081986": { "compartment": "compartment_12045", "id": "reaction_10081986", "reactome": "R-BTA-6807052", "name": "EBP isomerizes ZYMSTNL to LTHSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807048" ], "products": [ "species_6807054" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10081988": { "compartment": "compartment_12045", "id": "reaction_10081988", "reactome": "R-BTA-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6807054", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6807057" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10081990": { "compartment": "compartment_12045", "id": "reaction_10081990", "reactome": "R-BTA-6807064", "name": "DHCR24 reduces ZYMOL to ZYMSTNL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194691" ], "products": [ "species_6807048", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041477": { "compartment": "compartment_70101", "id": "reaction_10041477", "reactome": "R-BTA-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194644", "species_29364" ], "products": [ "species_194735", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10038347": { "compartment": "compartment_70101", "id": "reaction_10038347", "reactome": "R-BTA-159425", "name": "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_194096" ], "products": [ "species_111294", "species_29356", "species_194073", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "species_193451", "CHEBI:16755", "species_192356", "CHEBI:28701", "ENSBTAT00000020170" ] }, "reaction_10041437": { "compartment": "compartment_876", "id": "reaction_10041437", "reactome": "R-BTA-194187", "name": "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041428", "species_192483", "species_74113" ], "products": [ "species_10041430", "species_83910" ], "modifiers": [ [ "species_10041434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014054", "CHEBI:17687", "CHEBI:28865", "CHEBI:16755", "CHEBI:36274", "species_193451", "CHEBI:9407", "A0A452DID8", "ENSBTAT00000014054", "species_193451", "CHEBI:17687", "CHEBI:36274", "CHEBI:16525", "CHEBI:16755", "CHEBI:28865", "ENSBTAT00000021363" ] }, "reaction_10085806": { "compartment": "compartment_70101", "id": "reaction_10085806", "reactome": "R-BTA-8873850", "name": "STARD5 binds DCA, LCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_10085802", "species_5357505" ], "products": [ "species_10085804" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014559", "species_5357505", "A1A4M6", "ENSBTAT00000014559", "species_176655" ] }, "reaction_10085291": { "compartment": "compartment_70101", "id": "reaction_10085291", "reactome": "R-BTA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10085288", "catalyst" ] ], "additional_components": [ "A0A3Q1LYV2", "ENSBTAT00000083446", "E1BBD8", "ENSBTAT00000017982", "E1BL67", "ENSBTAT00000044841", "A0A3Q1M0E7", "ENSBTAT00000066543", "A0A3Q1MW81", "ENSBTAT00000066543" ] }, "reaction_10041097": { "compartment": "compartment_70101", "id": "reaction_10041097", "reactome": "R-BTA-191972", "name": "27-hydroxycholesterol is 7alpha-hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_176617", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192194" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10041369": { "compartment": "compartment_70101", "id": "reaction_10041369", "reactome": "R-BTA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041371": { "compartment": "compartment_70101", "id": "reaction_10041371", "reactome": "R-BTA-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192194" ], "products": [ "species_70106", "species_193835", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041373": { "compartment": "compartment_70101", "id": "reaction_10041373", "reactome": "R-BTA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041375": { "compartment": "compartment_70101", "id": "reaction_10041375", "reactome": "R-BTA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041377": { "compartment": "compartment_70101", "id": "reaction_10041377", "reactome": "R-BTA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041208": { "compartment": "compartment_70101", "id": "reaction_10041208", "reactome": "R-BTA-192137", "name": "THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041179": { "compartment": "compartment_5460", "id": "reaction_10041179", "reactome": "R-BTA-192054", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_191968", "species_113600" ], "products": [ "species_113563", "species_192161", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041210": { "compartment": "compartment_70101", "id": "reaction_10041210", "reactome": "R-BTA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041308": { "compartment": "compartment_17951", "id": "reaction_10041308", "reactome": "R-BTA-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192356" ], "products": [ "species_193451", "species_193514" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10041310": { "compartment": "compartment_5460", "id": "reaction_10041310", "reactome": "R-BTA-193393", "name": "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193436", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193387", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041104": { "compartment": "compartment_5460", "id": "reaction_10041104", "reactome": "R-BTA-191999", "name": "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_192078", "species_113529", "species_113600" ], "products": [ "species_192201", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041170": { "compartment": "compartment_70101", "id": "reaction_10041170", "reactome": "R-BTA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041301": { "compartment": "compartment_17951", "id": "reaction_10041301", "reactome": "R-BTA-193369", "name": "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_193442" ], "products": [ "species_113575", "species_193459" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041204": { "compartment": "compartment_70101", "id": "reaction_10041204", "reactome": "R-BTA-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192114" ], "products": [ "species_70106", "species_192136", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041172": { "compartment": "compartment_5460", "id": "reaction_10041172", "reactome": "R-BTA-192042", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192201", "species_113563" ], "products": [ "species_113529", "species_191968", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041111": { "compartment": "compartment_70101", "id": "reaction_10041111", "reactome": "R-BTA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041321": { "compartment": "compartment_70101", "id": "reaction_10041321", "reactome": "R-BTA-193424", "name": "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193505" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041323": { "compartment": "compartment_17951", "id": "reaction_10041323", "reactome": "R-BTA-193452", "name": "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193429" ], "products": [ "species_193442" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041226": { "compartment": "compartment_17951", "id": "reaction_10041226", "reactome": "R-BTA-192335", "name": "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_192316" ], "products": [ "species_113575", "species_192342" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041197": { "compartment": "compartment_70101", "id": "reaction_10041197", "reactome": "R-BTA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041325": { "compartment": "compartment_5460", "id": "reaction_10041325", "reactome": "R-BTA-193460", "name": "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193435", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193440", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041327": { "compartment": "compartment_5460", "id": "reaction_10041327", "reactome": "R-BTA-193497", "name": "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_193387" ], "products": [ "species_193435", "species_113529", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041186": { "compartment": "compartment_17951", "id": "reaction_10041186", "reactome": "R-BTA-192056", "name": "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192308" ], "products": [ "species_192316" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041317": { "compartment": "compartment_70101", "id": "reaction_10041317", "reactome": "R-BTA-193401", "name": "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041319": { "compartment": "compartment_70101", "id": "reaction_10041319", "reactome": "R-BTA-193407", "name": "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_193505", "species_76194" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10085316": { "compartment": "compartment_70101", "id": "reaction_10085316", "reactome": "R-BTA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027095" ] }, "reaction_10076009": { "compartment": "compartment_7660", "id": "reaction_10076009", "reactome": "R-BTA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10069573", "species_10069565" ], "products": [ "species_10076007" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000080567", "ENSBTAT00000010319", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077396": { "compartment": "compartment_7660", "id": "reaction_10077396", "reactome": "R-BTA-6782943", "name": "UV-DDB ubiquitinates XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076069", "species_10036828" ], "products": [ "species_10077087" ], "modifiers": [ [ "species_10076069", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077108": { "compartment": "compartment_7660", "id": "reaction_10077108", "reactome": "R-BTA-5696655", "name": "PARP1 or PARP2 PARylates DDB2 and autoPARylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077089", "species_427523" ], "products": [ "species_427497", "species_10077106" ], "modifiers": [], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740" ] }, "reaction_10076071": { "compartment": "compartment_7660", "id": "reaction_10076071", "reactome": "R-BTA-5691006", "name": "XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076007", "species_10076067", "species_5688114" ], "products": [ "species_10076069", "species_10076065" ], "modifiers": [], "additional_components": [ "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128" ] }, "reaction_10077016": { "compartment": "compartment_7660", "id": "reaction_10077016", "reactome": "R-BTA-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077009" ], "products": [ "species_10036828", "species_10036653" ], "modifiers": [ [ "species_10077013", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q1LZ75", "ENSBTAT00000023078", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000023078", "ENSBTAT00000067380" ] }, "reaction_10036661": { "compartment": "compartment_7660", "id": "reaction_10036661", "reactome": "R-BTA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036657", "species_10036653" ], "products": [ "species_10036659" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046336", "ENSBTAT00000023078", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336" ] }, "reaction_10037517": { "compartment": "compartment_70101", "id": "reaction_10037517", "reactome": "R-BTA-114600", "name": "Fyn/Lyn-mediated phosphorylation of FcR1 gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037504" ], "products": [ "species_29370", "species_10037514" ], "modifiers": [ [ "species_10037504", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420" ] }, "reaction_10049071": { "compartment": "compartment_876", "id": "reaction_10049071", "reactome": "R-BTA-429497", "name": "SLP-76 stimulates PLC gamma 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049069" ], "products": [ "species_10037554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10049395": { "compartment": "compartment_70101", "id": "reaction_10049395", "reactome": "R-BTA-437162", "name": "PI3K alpha, beta, gamma convert PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047493", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10049426": { "compartment": "compartment_70101", "id": "reaction_10049426", "reactome": "R-BTA-442291", "name": "VAV2 is a GEF for Rho/Rac family kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049418" ], "products": [ "species_29420", "species_10049420" ], "modifiers": [ [ "species_10049423", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000086853" ] }, "reaction_10037557": { "compartment": "compartment_70101", "id": "reaction_10037557", "reactome": "R-BTA-114689", "name": "PLC gamma 2-mediated PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10037554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10037588": { "compartment": "compartment_70101", "id": "reaction_10037588", "reactome": "R-BTA-139842", "name": "Binding of Syk tyrosine kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10037514" ], "products": [ "species_10037586" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10050630": { "compartment": "compartment_70101", "id": "reaction_10050630", "reactome": "R-BTA-453183", "name": "p-Y348-SYK dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050628" ], "products": [ "species_10050626", "species_10037514" ], "modifiers": [], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168", "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420" ] }, "reaction_10047475": { "compartment": "compartment_70101", "id": "reaction_10047475", "reactome": "R-BTA-392195", "name": "Gi activation by P2Y purinoceptor 12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047470" ], "products": [ "species_29420", "species_10047472" ], "modifiers": [ [ "species_10047470", "catalyst" ] ], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370" ] }, "reaction_10049039": { "compartment": "compartment_70101", "id": "reaction_10049039", "reactome": "R-BTA-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10036954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10047985": { "compartment": "compartment_70101", "id": "reaction_10047985", "reactome": "R-BTA-418662", "name": "Src activation following P2Y purinoceptor activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040957" ], "products": [ "species_10047983" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000011767" ] }, "reaction_10037201": { "compartment": "compartment_7660", "id": "reaction_10037201", "reactome": "R-BTA-112435", "name": "Formation of Elongin BC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037197", "species_10037193" ], "products": [ "species_10037199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026036", "ENSBTAT00000078734", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036" ] }, "reaction_10037185": { "compartment": "compartment_7660", "id": "reaction_10037185", "reactome": "R-BTA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037181", "species_10037177" ], "products": [ "species_10037183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027214", "ENSBTAT00000073946", "A6QQT5", "ENSBTAT00000073946", "E1BNP8", "ENSBTAT00000027214" ] }, "reaction_10037187": { "compartment": "compartment_7660", "id": "reaction_10037187", "reactome": "R-BTA-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037108", "species_10037098" ], "products": [ "species_10037110" ], "modifiers": [], "additional_components": [ "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231", "ENSBTAT00000006162", "Q5EAB2", "ENSBTAT00000006162", "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231" ] }, "reaction_10037189": { "compartment": "compartment_7660", "id": "reaction_10037189", "reactome": "R-BTA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037135", "species_10037130" ], "products": [ "species_10037137" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070366", "ENSBTAT00000071171", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366" ] }, "reaction_10037207": { "compartment": "compartment_7660", "id": "reaction_10037207", "reactome": "R-BTA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037173" ], "products": [ "species_10037173" ], "modifiers": [], "additional_components": [ "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006" ] }, "reaction_10081897": { "compartment": "compartment_70101", "id": "reaction_10081897", "reactome": "R-BTA-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081893" ], "products": [ "species_10081895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086118", "ENSBTAT00000086118" ] }, "reaction_10037264": { "compartment": "compartment_17906", "id": "reaction_10037264", "reactome": "R-BTA-114307", "name": "Release of SMAC (DIABLO) from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037260" ], "products": [ "species_10037262" ], "modifiers": [ [ "species_10037235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005496", "ENSBTAT00000005496", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10091186": { "compartment": "compartment_70101", "id": "reaction_10091186", "reactome": "R-BTA-9627106", "name": "SMAC (DIABLO) forms dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037262" ], "products": [ "species_10037285" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005496", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10049241": { "compartment": "compartment_876", "id": "reaction_10049241", "reactome": "R-BTA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049243": { "compartment": "compartment_876", "id": "reaction_10049243", "reactome": "R-BTA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049262": { "compartment": "compartment_876", "id": "reaction_10049262", "reactome": "R-BTA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049259", "catalyst" ] ], "additional_components": [ "O77750", "ENSBTAT00000082069" ] }, "reaction_10049253": { "compartment": "compartment_876", "id": "reaction_10049253", "reactome": "R-BTA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049250", "catalyst" ] ], "additional_components": [ "P79099", "ENSBTAT00000011024" ] }, "reaction_10049271": { "compartment": "compartment_876", "id": "reaction_10049271", "reactome": "R-BTA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10049268", "catalyst" ] ], "additional_components": [ "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051145": { "compartment": "compartment_876", "id": "reaction_10051145", "reactome": "R-BTA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051148": { "compartment": "compartment_876", "id": "reaction_10051148", "reactome": "R-BTA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051150": { "compartment": "compartment_876", "id": "reaction_10051150", "reactome": "R-BTA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051136": { "compartment": "compartment_876", "id": "reaction_10051136", "reactome": "R-BTA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10051141": { "compartment": "compartment_876", "id": "reaction_10051141", "reactome": "R-BTA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051143": { "compartment": "compartment_876", "id": "reaction_10051143", "reactome": "R-BTA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10041050": { "compartment": "compartment_70101", "id": "reaction_10041050", "reactome": "R-BTA-191784", "name": "snRNA Cap hypermethylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041043" ], "products": [ "species_10041031" ], "modifiers": [ [ "species_10041047", "catalyst" ] ], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:2274", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000007749" ] }, "reaction_10041039": { "compartment": "compartment_70101", "id": "reaction_10041039", "reactome": "R-BTA-191763", "name": "snRNP:Snurportin complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041031", "species_10041035" ], "products": [ "species_10041037" ], "modifiers": [], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000076267", "Q2TBK8", "ENSBTAT00000076267", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604" ] }, "reaction_10039916": { "compartment": "compartment_17957", "id": "reaction_10039916", "reactome": "R-BTA-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174932", "species_174384" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "species_159154", "CHEBI:17688", "CHEBI:63860", "CHEBI:32663", "ENSBTAT00000076879" ] }, "reaction_10076785": { "compartment": "compartment_5460", "id": "reaction_10076785", "reactome": "R-BTA-5694563", "name": "ABHD10 hydrolyses MPAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694574", "species_113521" ], "products": [ "species_5694569", "species_5694565" ], "modifiers": [ [ "species_10076782", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006038" ] }, "reaction_10038336": { "compartment": "compartment_17957", "id": "reaction_10038336", "reactome": "R-BTA-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_159149", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10038338": { "compartment": "compartment_17957", "id": "reaction_10038338", "reactome": "R-BTA-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10039749": { "compartment": "compartment_70101", "id": "reaction_10039749", "reactome": "R-BTA-173597", "name": "UDP-glucose is oxidised to UDP-glucuronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410", "species_29360" ], "products": [ "species_70106", "species_158601", "species_73473" ], "modifiers": [ [ "species_10039746", "catalyst" ] ], "additional_components": [ "P12378", "ENSBTAT00000019302" ] }, "reaction_10040682": { "compartment": "compartment_5460", "id": "reaction_10040682", "reactome": "R-BTA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10040679", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "A0A452DI36", "ENSBTAT00000005380" ] }, "reaction_10040654": { "compartment": "compartment_17927", "id": "reaction_10040654", "reactome": "R-BTA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10040651", "catalyst" ] ], "additional_components": [ "E1BKY9", "ENSBTAT00000005398" ] }, "reaction_10040688": { "compartment": "compartment_70101", "id": "reaction_10040688", "reactome": "R-BTA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10040669" ], "products": [ "species_10040686", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_190173" ] }, "reaction_10040672": { "compartment": "compartment_70101", "id": "reaction_10040672", "reactome": "R-BTA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10040669", "catalyst" ] ], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315" ] }, "reaction_10066416": { "compartment": "compartment_5460", "id": "reaction_10066416", "reactome": "R-BTA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10066413", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020336" ] }, "reaction_10040645": { "compartment": "compartment_70101", "id": "reaction_10040645", "reactome": "R-BTA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10040642", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q2KIN5", "ENSBTAT00000007052" ] }, "reaction_10040663": { "compartment": "compartment_17927", "id": "reaction_10040663", "reactome": "R-BTA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10040660", "catalyst" ] ], "additional_components": [ "P56602", "ENSBTAT00000061124", "species_113596" ] }, "reaction_10038380": { "compartment": "compartment_5460", "id": "reaction_10038380", "reactome": "R-BTA-159567", "name": "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159559" ], "products": [ "species_159448", "species_159450", "species_159557" ], "modifiers": [ [ "species_10038377", "catalyst" ] ], "additional_components": [ "A7MBE6", "ENSBTAT00000025874" ] }, "reaction_10038382": { "compartment": "compartment_5460", "id": "reaction_10038382", "reactome": "R-BTA-159574", "name": "salicylate-CoA + glycine => salicyluric acid + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159557" ], "products": [ "species_29374", "species_159572" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10083864": { "compartment": "compartment_984", "id": "reaction_10083864", "reactome": "R-BTA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083852": { "compartment": "compartment_984", "id": "reaction_10083852", "reactome": "R-BTA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10083849", "catalyst" ] ], "additional_components": [ "CHEBI:16039", "species_29438", "species_29494", "species_110614", "species_113592", "species_2509811", "species_29370", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "G3MZH7", "ENSBTAT00000063714" ] }, "reaction_10083873": { "compartment": "compartment_17963", "id": "reaction_10083873", "reactome": "R-BTA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_727810", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083889": { "compartment": "compartment_984", "id": "reaction_10083889", "reactome": "R-BTA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10083886", "catalyst" ] ], "additional_components": [ "species_2509811", "species_205687", "species_29420", "species_110094", "species_109402", "species_2509792", "species_727810", "species_113578", "Q2KJI4", "ENSBTAT00000081265", "species_29926", "species_74016" ] }, "reaction_10083861": { "compartment": "compartment_984", "id": "reaction_10083861", "reactome": "R-BTA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083876": { "compartment": "compartment_17963", "id": "reaction_10083876", "reactome": "R-BTA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110614", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083926": { "compartment": "compartment_528865", "id": "reaction_10083926", "reactome": "R-BTA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10083923", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_110094", "species_205687", "species_29420", "species_74016", "G3MYV7", "ENSBTAT00000062934" ] }, "reaction_10066684": { "compartment": "compartment_7660", "id": "reaction_10066684", "reactome": "R-BTA-3215310", "name": "USP7 deubiquitinates TP53 and counteracts MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066675" ], "products": [ "species_10066677", "species_10036828" ], "modifiers": [ [ "species_10066681", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000007177" ] }, "reaction_10081541": { "compartment": "compartment_7660", "id": "reaction_10081541", "reactome": "R-BTA-6804441", "name": "RNF34 or RFFL ubiquitinates phosphorylated TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10036828" ], "products": [ "species_10081534" ], "modifiers": [ [ "species_10081538", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "ENSBTAT00000083405" ] }, "reaction_10066737": { "compartment": "compartment_7660", "id": "reaction_10066737", "reactome": "R-BTA-3222116", "name": "L3MBTL1 binds TP53 monomethylated on K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066733", "species_10066728" ], "products": [ "species_10066735" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000069634", "A0A3Q1M5Y5", "ENSBTAT00000069634", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081877": { "compartment": "compartment_7660", "id": "reaction_10081877", "reactome": "R-BTA-6805730", "name": "SETD9 methylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10033524" ], "products": [ "species_77502", "species_10081870" ], "modifiers": [ [ "species_10081874", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000052840" ] }, "reaction_10066724": { "compartment": "compartment_7660", "id": "reaction_10066724", "reactome": "R-BTA-3222093", "name": "BRD7 binds TP53 and EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066720", "species_10053052" ], "products": [ "species_10066722" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000067101", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10072550": { "compartment": "compartment_7660", "id": "reaction_10072550", "reactome": "R-BTA-5628871", "name": "BRD7 promotes EP300-mediated acetylation of TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066722", "species_113560" ], "products": [ "species_2485002", "species_10072547" ], "modifiers": [ [ "species_10066722", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "A6QLF6", "ENSBTAT00000067101", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10080811": { "compartment": "compartment_7660", "id": "reaction_10080811", "reactome": "R-BTA-6799777", "name": "TP53 family members bind PPP1R13B or TP53BP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080807", "species_10078666" ], "products": [ "species_10080809" ], "modifiers": [], "additional_components": [ "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457" ] }, "reaction_10081530": { "compartment": "compartment_7660", "id": "reaction_10081530", "reactome": "R-BTA-6804425", "name": "TP53 binds POU4F2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081526", "species_10033524" ], "products": [ "species_10081528" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007421", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BLU8", "ENSBTAT00000007421" ] }, "reaction_10080797": { "compartment": "compartment_7660", "id": "reaction_10080797", "reactome": "R-BTA-6799761", "name": "TP53 binds PPP1R13L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078666", "species_10080793" ], "products": [ "species_10080795" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "ENSBTAT00000070207", "A0A3Q1M2S9", "ENSBTAT00000070207", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066764": { "compartment": "compartment_7660", "id": "reaction_10066764", "reactome": "R-BTA-3222259", "name": "PHF20 binds TP53 dimethylated on K370 and K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066754", "species_10066760" ], "products": [ "species_10066762" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BMS9", "ENSBTAT00000007321" ] }, "reaction_10081889": { "compartment": "compartment_7660", "id": "reaction_10081889", "reactome": "R-BTA-6805792", "name": "p-S291-PHF20 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081885" ], "products": [ "species_10081887" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "ENSBTAT00000007321" ] }, "reaction_10081522": { "compartment": "compartment_7660", "id": "reaction_10081522", "reactome": "R-BTA-6804402", "name": "TP53 binds POU4F1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081518" ], "products": [ "species_10081520" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000077824", "A0A3Q1MTW2", "ENSBTAT00000077824", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078474": { "compartment": "compartment_7660", "id": "reaction_10078474", "reactome": "R-BTA-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078470", "species_10037102" ], "products": [ "species_10078472" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002003", "ENSBTAT00000063128", "G3N172", "ENSBTAT00000063128", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10072571": { "compartment": "compartment_70101", "id": "reaction_10072571", "reactome": "R-BTA-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072563", "species_29408" ], "products": [ "species_29356", "species_10072568" ], "modifiers": [ [ "species_10072563", "catalyst" ] ], "additional_components": [ "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751" ] }, "reaction_10072557": { "compartment": "compartment_70101", "id": "reaction_10072557", "reactome": "R-BTA-5628905", "name": "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30533" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10072554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022146" ] }, "reaction_10072591": { "compartment": "compartment_70101", "id": "reaction_10072591", "reactome": "R-BTA-5631903", "name": "SESN1,2,3 bind overoxidized PRDX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072587", "species_10072568" ], "products": [ "species_10072589" ], "modifiers": [], "additional_components": [ "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532" ] }, "reaction_10072595": { "compartment": "compartment_70101", "id": "reaction_10072595", "reactome": "R-BTA-5631941", "name": "SESN1,2,3 bind AMPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046570", "species_10072587" ], "products": [ "species_10072593" ], "modifiers": [], "additional_components": [ "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10072614": { "compartment": "compartment_70101", "id": "reaction_10072614", "reactome": "R-BTA-5632738", "name": "DDIT4 binds 14-3-3 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10072610" ], "products": [ "species_10072612" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000000187", "Q08E62", "ENSBTAT00000000187", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10053210": { "compartment": "compartment_876", "id": "reaction_10053210", "reactome": "R-BTA-937311", "name": "ATP4A/12A:ATP4B exchanges K+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_70106", "species_113592" ], "products": [ "species_351626", "species_29804", "species_29372", "species_29370" ], "modifiers": [ [ "species_10053207", "catalyst" ] ], "additional_components": [ "F1MXW4", "ENSBTAT00000011569", "A0A3Q1M1C8", "ENSBTAT00000073742", "E1BLX8", "ENSBTAT00000026587" ] }, "reaction_10053258": { "compartment": "compartment_876", "id": "reaction_10053258", "reactome": "R-BTA-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947594" ], "products": [ "species_29372", "species_29370", "species_947588" ], "modifiers": [ [ "species_10053255", "catalyst" ] ], "additional_components": [ "species_1602375", "species_1500646", "species_1500646", "species_1602375", "F1MZ89", "ENSBTAT00000035192", "A0A3Q1MCF3", "ENSBTAT00000082277", "A0A3Q1M082", "ENSBTAT00000075591", "F1N3G6", "ENSBTAT00000021914" ] }, "reaction_10076172": { "compartment": "compartment_70101", "id": "reaction_10076172", "reactome": "R-BTA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10076169", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009383" ] }, "reaction_10076179": { "compartment": "compartment_70101", "id": "reaction_10076179", "reactome": "R-BTA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10076176", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010946" ] }, "reaction_10053143": { "compartment": "compartment_20699", "id": "reaction_10053143", "reactome": "R-BTA-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_74016" ], "products": [ "species_29372", "species_29370", "species_167012" ], "modifiers": [ [ "species_10053140", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LYD6", "ENSBTAT00000086525" ] }, "reaction_10071254": { "compartment": "compartment_70101", "id": "reaction_10071254", "reactome": "R-BTA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10071251", "catalyst" ] ], "additional_components": [ "F1N272", "ENSBTAT00000021694", "A0A3Q1M0A4", "ENSBTAT00000077002" ] }, "reaction_10057787": { "compartment": "compartment_5460", "id": "reaction_10057787", "reactome": "R-BTA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379721", "species_10057762", "species_10057776" ], "products": [ "species_10057778", "species_379697", "species_10057784" ], "modifiers": [ [ "species_10057762", "catalyst" ], [ "species_10057776", "catalyst" ] ], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "CHEBI:33739", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33737", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630" ] }, "reaction_10057792": { "compartment": "compartment_5460", "id": "reaction_10057792", "reactome": "R-BTA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113531", "species_10057790" ], "products": [ "species_10057762" ], "modifiers": [], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648" ] }, "reaction_10086272": { "compartment": "compartment_5460", "id": "reaction_10086272", "reactome": "R-BTA-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086254", "species_10086264" ], "products": [ "species_10086252", "species_10086266" ], "modifiers": [ [ "species_10086270", "catalyst" ] ], "additional_components": [ "A6QLZ6", "ENSBTAT00000017860", "CHEBI:33739", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "ENSBTAT00000017860", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "CHEBI:49883", "ENSBTAT00000044111" ] }, "reaction_10070682": { "compartment": "compartment_70101", "id": "reaction_10070682", "reactome": "R-BTA-5218891", "name": "RIPK1:RIPK3 oligomer binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070678", "species_10067320" ], "products": [ "species_10070680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10072346": { "compartment": "compartment_876", "id": "reaction_10072346", "reactome": "R-BTA-5620975", "name": "MLKL binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067330", "species_5620974" ], "products": [ "species_10072328" ], "modifiers": [ [ "species_10072344", "inhibitor" ], [ "species_10072338", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_179838", "species_1806180", "species_6810412", "species_179838", "species_1806180", "species_6810412", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165", "Q08DN8", "ENSBTAT00000013135", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070684": { "compartment": "compartment_70101", "id": "reaction_10070684", "reactome": "R-BTA-5218905", "name": "RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067318" ], "products": [ "species_10067320" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070689": { "compartment": "compartment_70101", "id": "reaction_10070689", "reactome": "R-BTA-5218906", "name": "RIPK3 phosphorylates MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_29370", "species_10070686" ], "modifiers": [ [ "species_10070680", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070531": { "compartment": "compartment_70101", "id": "reaction_10070531", "reactome": "R-BTA-5213464", "name": "RIPK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070524" ], "products": [ "species_29370", "species_10070526" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070534": { "compartment": "compartment_70101", "id": "reaction_10070534", "reactome": "R-BTA-5213466", "name": "RIPK3 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070526" ], "products": [ "species_10067318", "species_29370" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10061064": { "compartment": "compartment_70101", "id": "reaction_10061064", "reactome": "R-BTA-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061067": { "compartment": "compartment_70101", "id": "reaction_10061067", "reactome": "R-BTA-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629753" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10060986": { "compartment": "compartment_70101", "id": "reaction_10060986", "reactome": "R-BTA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10060509", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022635" ] }, "reaction_10060938": { "compartment": "compartment_70101", "id": "reaction_10060938", "reactome": "R-BTA-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_870330" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061134": { "compartment": "compartment_70101", "id": "reaction_10061134", "reactome": "R-BTA-1855232", "name": "I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629746" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061061": { "compartment": "compartment_70101", "id": "reaction_10061061", "reactome": "R-BTA-1855208", "name": "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629739" ], "products": [ "species_29372", "species_1629753" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061014": { "compartment": "compartment_70101", "id": "reaction_10061014", "reactome": "R-BTA-1855180", "name": "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629769" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10061046": { "compartment": "compartment_70101", "id": "reaction_10061046", "reactome": "R-BTA-1855202", "name": "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629746" ], "products": [ "species_29372", "species_1629731" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10044666": { "compartment": "compartment_876", "id": "reaction_10044666", "reactome": "R-BTA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10044663", "catalyst" ] ], "additional_components": [ "A0A3Q1M833", "ENSBTAT00000085091" ] }, "reaction_10074493": { "compartment": "compartment_70101", "id": "reaction_10074493", "reactome": "R-BTA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10074490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004518" ] }, "reaction_10046707": { "compartment": "compartment_17947", "id": "reaction_10046707", "reactome": "R-BTA-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_382577" ], "products": [ "species_382571", "species_29372", "species_29370" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10058216": { "compartment": "compartment_70101", "id": "reaction_10058216", "reactome": "R-BTA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10058213", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ85", "ENSBTAT00000076899", "E1BNL1", "ENSBTAT00000007685", "F1N4I6", "ENSBTAT00000014417", "F1N3Y6", "ENSBTAT00000026744", "F1MUC1", "ENSBTAT00000013298" ] }, "reaction_10074360": { "compartment": "compartment_984", "id": "reaction_10074360", "reactome": "R-BTA-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429802", "species_113592" ], "products": [ "species_382539", "species_29372", "species_29370" ], "modifiers": [ [ "species_10074357", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070307" ] }, "reaction_10070728": { "compartment": "compartment_70101", "id": "reaction_10070728", "reactome": "R-BTA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10070725", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ87", "ENSBTAT00000070992" ] }, "reaction_10057832": { "compartment": "compartment_17906", "id": "reaction_10057832", "reactome": "R-BTA-1369065", "name": "ABCB6 transports porphyrin from cytosol to mitchondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1369066", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1369027" ], "modifiers": [ [ "species_10057829", "catalyst" ] ], "additional_components": [ "A5D7P7", "ENSBTAT00000027459" ] }, "reaction_10046698": { "compartment": "compartment_70616", "id": "reaction_10046698", "reactome": "R-BTA-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_189444", "species_113521" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10046695", "catalyst" ] ], "additional_components": [ "A0A3Q1MUB7", "ENSBTAT00000085390" ] }, "reaction_10058469": { "compartment": "compartment_876", "id": "reaction_10058469", "reactome": "R-BTA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10058466", "catalyst" ] ], "additional_components": [ "A0A3Q1MB23", "ENSBTAT00000080713", "A0A3Q1LS24", "ENSBTAT00000073046" ] }, "reaction_10070743": { "compartment": "compartment_70101", "id": "reaction_10070743", "reactome": "R-BTA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070739", "species_10034379" ], "products": [ "species_10070741" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070886", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "A0A3Q1NB13", "ENSBTAT00000070886" ] }, "reaction_10088584": { "compartment": "compartment_7660", "id": "reaction_10088584", "reactome": "R-BTA-8954056", "name": "E2F6 binds TFDP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056555" ], "products": [ "species_10088582" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000076561", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088554": { "compartment": "compartment_7660", "id": "reaction_10088554", "reactome": "R-BTA-8953111", "name": "E2F6 binds TFDP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056551" ], "products": [ "species_10088552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000084839", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10089578": { "compartment": "compartment_7660", "id": "reaction_10089578", "reactome": "R-BTA-9007447", "name": "E2F6 forms the PRC1L4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10089554", "species_10089550", "species_10066826", "species_10081545" ], "products": [ "species_10089576" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000013026", "ENSBTAT00000076903", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "ENSBTAT00000085264", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "A6H7C4", "ENSBTAT00000076903", "E1BJL2", "ENSBTAT00000013026", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088564": { "compartment": "compartment_7660", "id": "reaction_10088564", "reactome": "R-BTA-8953115", "name": "E2F6:TFDP1 binds to MGA:MAX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088560", "species_10088552" ], "products": [ "species_10088562" ], "modifiers": [], "additional_components": [ "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10088596": { "compartment": "compartment_7660", "id": "reaction_10088596", "reactome": "R-BTA-8954082", "name": "E2F6 binds the PRC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088592", "species_10088586" ], "products": [ "species_10088594" ], "modifiers": [], "additional_components": [ "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711" ] }, "reaction_10089574": { "compartment": "compartment_7660", "id": "reaction_10089574", "reactome": "R-BTA-9007283", "name": "CBX3 and PRC1.6 associate with E2F6.com-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089570", "species_10089550", "species_10089560" ], "products": [ "species_10089572" ], "modifiers": [], "additional_components": [ "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "ENSBTAT00000076903", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A6H7C4", "ENSBTAT00000076903", "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10091049": { "compartment": "compartment_7660", "id": "reaction_10091049", "reactome": "R-BTA-9617927", "name": "FOXO4 binds ATXN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042669", "species_10075370" ], "products": [ "species_10091047" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091096": { "compartment": "compartment_7660", "id": "reaction_10091096", "reactome": "R-BTA-9620532", "name": "SIRT1,SIRT3 deacetylate FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427523", "species_10091084" ], "products": [ "species_427497", "species_427498", "species_10042665" ], "modifiers": [ [ "species_10091093", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "G5E521", "ENSBTAT00000002648", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10091089": { "compartment": "compartment_7660", "id": "reaction_10091089", "reactome": "R-BTA-9620515", "name": "KAT2B,EP300 acetylate FOXO3 under oxidative stress", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10042665" ], "products": [ "species_2485002", "species_10091084" ], "modifiers": [ [ "species_10091086", "catalyst" ], [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10091184": { "compartment": "compartment_7660", "id": "reaction_10091184", "reactome": "R-BTA-9626928", "name": "CREBBP binds FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10042661" ], "products": [ "species_10091182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10091017": { "compartment": "compartment_7660", "id": "reaction_10091017", "reactome": "R-BTA-9614414", "name": "AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042696" ], "products": [ "species_10091015" ], "modifiers": [], "additional_components": [ "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418", "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091033": { "compartment": "compartment_70101", "id": "reaction_10091033", "reactome": "R-BTA-9614564", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091013", "species_10037662" ], "products": [ "species_10091031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "P63103", "ENSBTAT00000000289", "P63103", "ENSBTAT00000000289", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091023": { "compartment": "compartment_70101", "id": "reaction_10091023", "reactome": "R-BTA-9614423", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091019", "species_10044088" ], "products": [ "species_10091021" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10091029": { "compartment": "compartment_70101", "id": "reaction_10091029", "reactome": "R-BTA-9614562", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091011", "species_10091025" ], "products": [ "species_10091027" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "F1N4K5", "ENSBTAT00000014920" ] }, "reaction_10088872": { "compartment": "compartment_7660", "id": "reaction_10088872", "reactome": "R-BTA-8956659", "name": "ABL1 phosphorylates YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10057280" ], "products": [ "species_113582", "species_10088870" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "ENSBTAT00000080797" ] }, "reaction_10088876": { "compartment": "compartment_7660", "id": "reaction_10088876", "reactome": "R-BTA-8956676", "name": "YAP1 binds TP73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088870", "species_10078664" ], "products": [ "species_10088874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10088887": { "compartment": "compartment_13231", "id": "reaction_10088887", "reactome": "R-BTA-8957241", "name": "TP73 tetramer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088880" ], "products": [ "species_10078664" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643" ] }, "reaction_10086458": { "compartment": "compartment_7660", "id": "reaction_10086458", "reactome": "R-BTA-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086449" ], "products": [ "species_77502", "species_10086455" ], "modifiers": [ [ "species_10086449", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086493": { "compartment": "compartment_7660", "id": "reaction_10086493", "reactome": "R-BTA-8936584", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086477" ], "products": [ "species_77502", "species_10086490" ], "modifiers": [ [ "species_10086477", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086509": { "compartment": "compartment_7660", "id": "reaction_10086509", "reactome": "R-BTA-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086504" ], "products": [ "species_77502", "species_10086506" ], "modifiers": [ [ "species_10086504", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086525": { "compartment": "compartment_7660", "id": "reaction_10086525", "reactome": "R-BTA-8937022", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086520" ], "products": [ "species_77502", "species_10086522" ], "modifiers": [ [ "species_10086520", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086541": { "compartment": "compartment_7660", "id": "reaction_10086541", "reactome": "R-BTA-8937113", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086536" ], "products": [ "species_77502", "species_10086538" ], "modifiers": [ [ "species_10086536", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086502": { "compartment": "compartment_7660", "id": "reaction_10086502", "reactome": "R-BTA-8936608", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086497" ], "products": [ "species_77502", "species_10086499" ], "modifiers": [ [ "species_10086497", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086518": { "compartment": "compartment_7660", "id": "reaction_10086518", "reactome": "R-BTA-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086513" ], "products": [ "species_77502", "species_10086515" ], "modifiers": [ [ "species_10086513", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086534": { "compartment": "compartment_7660", "id": "reaction_10086534", "reactome": "R-BTA-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086529" ], "products": [ "species_77502", "species_10086531" ], "modifiers": [ [ "species_10086529", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086638": { "compartment": "compartment_161320", "id": "reaction_10086638", "reactome": "R-BTA-8938108", "name": "SERPINB13 binds cathepsin L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086634", "species_10063945" ], "products": [ "species_10086636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005068", "ENSBTAT00000036427", "A0A452DK38", "ENSBTAT00000036427", "E1BIP8", "ENSBTAT00000005068" ] }, "reaction_10084922": { "compartment": "compartment_7660", "id": "reaction_10084922", "reactome": "R-BTA-8864595", "name": "TFAP2B homodimer binds YEATS4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084918", "species_10084916" ], "products": [ "species_10084920" ], "modifiers": [], "additional_components": [ "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000002913", "Q32LE1", "ENSBTAT00000002913", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084911": { "compartment": "compartment_70101", "id": "reaction_10084911", "reactome": "R-BTA-8864577", "name": "TFAP2C translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084905" ], "products": [ "species_10066845" ], "modifiers": [ [ "species_10084907", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000002671", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084895": { "compartment": "compartment_7660", "id": "reaction_10084895", "reactome": "R-BTA-8864307", "name": "TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10084879", "species_10053052", "species_10084891" ], "products": [ "species_10084893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000021556", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "E1B8D6", "ENSBTAT00000021556", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10084881": { "compartment": "compartment_7660", "id": "reaction_10084881", "reactome": "R-BTA-8864278", "name": "AP-2 (TFAP2) transcription factors form homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084877" ], "products": [ "species_10084879" ], "modifiers": [], "additional_components": [ "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084935": { "compartment": "compartment_7660", "id": "reaction_10084935", "reactome": "R-BTA-8865265", "name": "TFAP2C homodimer binds MYC and KDM5B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069764", "species_10077310", "species_10066847" ], "products": [ "species_10084933" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028871", "ENSBTAT00000076263", "Q0VC14", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "Q2HJ27", "ENSBTAT00000076263", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10084909": { "compartment": "compartment_70101", "id": "reaction_10084909", "reactome": "R-BTA-8864569", "name": "WWOX binds TFAP2C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10084905" ], "products": [ "species_10084907" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084903": { "compartment": "compartment_7660", "id": "reaction_10084903", "reactome": "R-BTA-8864343", "name": "KCTD1 binds TFAP2 homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084899", "species_10084879" ], "products": [ "species_10084901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068462", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "A0A3Q1MKM9", "ENSBTAT00000068462" ] }, "reaction_10063400": { "compartment": "compartment_7660", "id": "reaction_10063400", "reactome": "R-BTA-2032781", "name": "WWTR1 (TAZ) binds TEAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063396", "species_10063378" ], "products": [ "species_10063398" ], "modifiers": [], "additional_components": [ "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10063390": { "compartment": "compartment_7660", "id": "reaction_10063390", "reactome": "R-BTA-2032775", "name": "YAP1 binds TEAD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057280", "species_10063386" ], "products": [ "species_10063388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000067627", "A0A3Q1N1G2", "ENSBTAT00000067627", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10085761": { "compartment": "compartment_7660", "id": "reaction_10085761", "reactome": "R-BTA-8871265", "name": "YAP1 binds TEAD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063394", "species_10057280" ], "products": [ "species_10085759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074335", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10046681": { "compartment": "compartment_7660", "id": "reaction_10046681", "reactome": "R-BTA-382096", "name": "Formation of NR-NCOR Corepressor Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10045690" ], "products": [ "species_10046679" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10054279": { "compartment": "compartment_7660", "id": "reaction_10054279", "reactome": "R-BTA-975040", "name": "KRAB-ZNF / KAP Interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053367", "species_10054275" ], "products": [ "species_10054277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008424", "Q17R08", "ENSBTAT00000080509", "Q17R08", "ENSBTAT00000080509", "E1BJG5", "ENSBTAT00000008424" ] }, "reaction_10065292": { "compartment": "compartment_876", "id": "reaction_10065292", "reactome": "R-BTA-2327738", "name": "DDR1 binds collagen type I, II, III, IV, V, XI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065286", "species_10065288" ], "products": [ "species_10065290" ], "modifiers": [], "additional_components": [ "E1BBP4", "ENSBTAT00000046062", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "E1BBP4", "ENSBTAT00000046062" ] }, "reaction_10068042": { "compartment": "compartment_70101", "id": "reaction_10068042", "reactome": "R-BTA-3465448", "name": "Caspase-8 and FLIP(L) processing at DISC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068032" ], "products": [ "species_10068038", "species_10068040" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068046": { "compartment": "compartment_876", "id": "reaction_10068046", "reactome": "R-BTA-3465459", "name": "FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10035386" ], "products": [ "species_10068044" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10067891": { "compartment": "compartment_876", "id": "reaction_10067891", "reactome": "R-BTA-3371359", "name": "FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10037981" ], "products": [ "species_10067889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10037985": { "compartment": "compartment_876", "id": "reaction_10037985", "reactome": "R-BTA-141156", "name": "TRAIL-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037981", "species_10035384" ], "products": [ "species_10037983" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10035396": { "compartment": "compartment_876", "id": "reaction_10035396", "reactome": "R-BTA-73945", "name": "FAS-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035386", "species_10035384" ], "products": [ "species_10035390" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000085853" ] }, "reaction_10037991": { "compartment": "compartment_70101", "id": "reaction_10037991", "reactome": "R-BTA-141159", "name": "TNF-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037987", "species_10035384" ], "products": [ "species_10037989" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853" ] }, "reaction_10043049": { "compartment": "compartment_70101", "id": "reaction_10043049", "reactome": "R-BTA-201637", "name": "Caspase-mediated cleavage of plectin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043" ], "products": [ "species_10043047", "species_10043045" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082561", "ENSBTAT00000082561", "ENSBTAT00000082561", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044762": { "compartment": "compartment_70101", "id": "reaction_10044762", "reactome": "R-BTA-350319", "name": "Caspase mediated cleavage of vimentin at IDVD (259)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044758", "species_10044760" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10043021": { "compartment": "compartment_70101", "id": "reaction_10043021", "reactome": "R-BTA-201628", "name": "Caspase-mediated cleavage of vimentin at DSVD (85)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10043018", "species_10043016" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043059": { "compartment": "compartment_70101", "id": "reaction_10043059", "reactome": "R-BTA-201639", "name": "Caspase-mediated cleavage of GAS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043053" ], "products": [ "species_10043057", "species_10043055" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028855", "ENSBTAT00000028855", "ENSBTAT00000028855", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044756": { "compartment": "compartment_70101", "id": "reaction_10044756", "reactome": "R-BTA-350318", "name": "Caspase-mediated cleavage of vimentin at TNLD (429)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044743", "species_10044745" ], "modifiers": [ [ "species_10044753", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044923": { "compartment": "compartment_7660", "id": "reaction_10044923", "reactome": "R-BTA-351936", "name": "Caspase-mediated cleavage of claspin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040063" ], "products": [ "species_10044912", "species_10044910" ], "modifiers": [ [ "species_10044920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074281", "ENSBTAT00000074281", "ENSBTAT00000074281", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044906": { "compartment": "compartment_70101", "id": "reaction_10044906", "reactome": "R-BTA-351901", "name": "Caspase-mediated cleavage of MST3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044900" ], "products": [ "species_10044902", "species_10044904" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747", "ENSBTAT00000075747", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10090573": { "compartment": "compartment_7660", "id": "reaction_10090573", "reactome": "R-BTA-9029680", "name": "Caspase-7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037229" ], "products": [ "species_10044920" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043039": { "compartment": "compartment_70101", "id": "reaction_10043039", "reactome": "R-BTA-201634", "name": "Caspase-mediated cleavage of FADK 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043033" ], "products": [ "species_10043037", "species_10043035" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085237", "ENSBTAT00000085237", "ENSBTAT00000085237", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044896": { "compartment": "compartment_12045", "id": "reaction_10044896", "reactome": "R-BTA-351894", "name": "Caspase mediated cleavage of BAP31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044887" ], "products": [ "species_10044893", "species_10044891", "species_10044889" ], "modifiers": [ [ "species_10044867", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044995": { "compartment": "compartment_7660", "id": "reaction_10044995", "reactome": "R-BTA-352268", "name": "Cleavage of Satb1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044989" ], "products": [ "species_10044993", "species_10044991" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028199", "ENSBTAT00000028199", "ENSBTAT00000028199", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044927": { "compartment": "compartment_13231", "id": "reaction_10044927", "reactome": "R-BTA-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044902" ], "products": [ "species_10044925" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747" ] }, "reaction_10044869": { "compartment": "compartment_70101", "id": "reaction_10044869", "reactome": "R-BTA-351863", "name": "Translocation of active caspase-8 to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037638" ], "products": [ "species_10044867" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037723": { "compartment": "compartment_70101", "id": "reaction_10037723", "reactome": "R-BTA-139918", "name": "Phosphorylation of BIM by JNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037716", "species_113592" ], "products": [ "species_10037718", "species_29370", "species_10037721" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "P61285", "ENSBTAT00000081563", "A0A3Q1NJ55", "ENSBTAT00000078264", "P61285", "ENSBTAT00000081563", "ENSBTAT00000078264", "ENSBTAT00000087439" ] }, "reaction_10037727": { "compartment": "compartment_70101", "id": "reaction_10037727", "reactome": "R-BTA-139919", "name": "Translocation of BIM to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037721" ], "products": [ "species_10037725" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000078264" ] }, "reaction_10037706": { "compartment": "compartment_70101", "id": "reaction_10037706", "reactome": "R-BTA-139909", "name": "Translocation of BMF to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037695" ], "products": [ "species_10037704" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077917", "ENSBTAT00000077917" ] }, "reaction_10037702": { "compartment": "compartment_70101", "id": "reaction_10037702", "reactome": "R-BTA-139908", "name": "Phosphorylation of DLC2 by MAPK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037690" ], "products": [ "species_29370", "species_10037695", "species_10037692" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "Q3MHR3", "ENSBTAT00000006190", "Q05KI3", "ENSBTAT00000077917", "ENSBTAT00000077917", "Q3MHR3", "ENSBTAT00000006190", "ENSBTAT00000087439" ] }, "reaction_10051181": { "compartment": "compartment_17906", "id": "reaction_10051181", "reactome": "R-BTA-508163", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037273", "species_10051177" ], "products": [ "species_10051179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264", "F6R2C4", "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264" ] }, "reaction_10037277": { "compartment": "compartment_17906", "id": "reaction_10037277", "reactome": "R-BTA-114352", "name": "Sequestration of tBID by BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037273" ], "products": [ "species_10037275" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000025701", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10051175": { "compartment": "compartment_17906", "id": "reaction_10051175", "reactome": "R-BTA-508162", "name": "BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051171", "species_10051167" ], "products": [ "species_10051173" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076163", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "Q05KJ0", "ENSBTAT00000076163" ] }, "reaction_10037289": { "compartment": "compartment_70101", "id": "reaction_10037289", "reactome": "R-BTA-114354", "name": "SMAC binds XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037283" ], "products": [ "species_10037287" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091191": { "compartment": "compartment_70101", "id": "reaction_10091191", "reactome": "R-BTA-9627350", "name": "SMAC (DIABLO) binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037281" ], "products": [ "species_10037291" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "ENSBTAT00000067597", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091197": { "compartment": "compartment_70101", "id": "reaction_10091197", "reactome": "R-BTA-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10091193" ], "products": [ "species_10091195" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118" ] }, "reaction_10091188": { "compartment": "compartment_70101", "id": "reaction_10091188", "reactome": "R-BTA-9627107", "name": "XIAP binds CASP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10037229" ], "products": [ "species_10037283" ], "modifiers": [ [ "species_10037285", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10039930": { "compartment": "compartment_70101", "id": "reaction_10039930", "reactome": "R-BTA-175987", "name": "NNMT transfers CH3 from AdoMet to PY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175973", "species_71284" ], "products": [ "species_175979", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10038238": { "compartment": "compartment_70101", "id": "reaction_10038238", "reactome": "R-BTA-158609", "name": "TPMT transfers CH3 from AdoMet to 6MP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158619", "species_71284" ], "products": [ "species_70106", "species_71285", "species_158611" ], "modifiers": [ [ "species_10038235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025698" ] }, "reaction_10076898": { "compartment": "compartment_70101", "id": "reaction_10076898", "reactome": "R-BTA-5696213", "name": "AS3MT transfers CH3 from AdoMet to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696224", "species_71284" ], "products": [ "species_5696211", "species_71285" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10071924": { "compartment": "compartment_70101", "id": "reaction_10071924", "reactome": "R-BTA-5603114", "name": "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10071921", "catalyst" ] ], "additional_components": [ "Q29RI9", "ENSBTAT00000016399", "A0A3Q1MZ37", "ENSBTAT00000075325", "species_29926", "species_74126" ] }, "reaction_10076900": { "compartment": "compartment_70101", "id": "reaction_10076900", "reactome": "R-BTA-5696220", "name": "AS3MT transfers CH3 from AdoMet to arsenite(3-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696216", "species_71284" ], "products": [ "species_71285", "species_5696214" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10035863": { "compartment": "compartment_17960", "id": "reaction_10035863", "reactome": "R-BTA-76386", "name": "CYP1A2 S-demethylates 6MMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76384", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_33153" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10076903": { "compartment": "compartment_70101", "id": "reaction_10076903", "reactome": "R-BTA-5696230", "name": "GSTO1 dimer reduces methylarsonate to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5696214" ], "products": [ "species_29356", "species_5696224", "species_111745" ], "modifiers": [ [ "species_10039980", "catalyst" ] ], "additional_components": [ "E1BJ08", "ENSBTAT00000017435" ] }, "reaction_10037800": { "compartment": "compartment_984", "id": "reaction_10037800", "reactome": "R-BTA-140664", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037795", "catalyst" ], [ "species_10037798", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037852": { "compartment": "compartment_984", "id": "reaction_10037852", "reactome": "R-BTA-140700", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037785", "catalyst" ], [ "species_10037850", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037948": { "compartment": "compartment_876", "id": "reaction_10037948", "reactome": "R-BTA-140870", "name": "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037921" ], "products": [ "species_10037945" ], "modifiers": [ [ "species_10037921", "catalyst" ] ], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037950": { "compartment": "compartment_984", "id": "reaction_10037950", "reactome": "R-BTA-140872", "name": "thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037945" ], "products": [ "species_10037829", "species_9693058" ], "modifiers": [], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037923": { "compartment": "compartment_984", "id": "reaction_10037923", "reactome": "R-BTA-140791", "name": "activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037919", "species_10037577" ], "products": [ "species_10037921" ], "modifiers": [], "additional_components": [ "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10071906": { "compartment": "compartment_876", "id": "reaction_10071906", "reactome": "R-BTA-5602080", "name": "Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037841", "species_10037835" ], "products": [ "species_10037843" ], "modifiers": [], "additional_components": [ "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10090181": { "compartment": "compartment_984", "id": "reaction_10090181", "reactome": "R-BTA-9015111", "name": "Factor Xa inhibitors binds Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037785" ], "products": [ "species_10037850" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037845": { "compartment": "compartment_984", "id": "reaction_10037845", "reactome": "R-BTA-140696", "name": "factor V -> factor Va + factor V activation peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037817" ], "products": [ "species_10037813", "species_10037819" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000023573", "species_74016", "F1N0I3", "ENSBTAT00000023573", "ENSBTAT00000023573", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10037815": { "compartment": "compartment_984", "id": "reaction_10037815", "reactome": "R-BTA-140686", "name": "factor Va + factor Xa -> Va:Xa complex (prothrombinase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037813", "species_10037807" ], "products": [ "species_10037795" ], "modifiers": [], "additional_components": [ "species_74016", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10090183": { "compartment": "compartment_984", "id": "reaction_10090183", "reactome": "R-BTA-9015122", "name": "Factor Xa inhibitors bind Va:Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037795" ], "products": [ "species_10037798" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037927": { "compartment": "compartment_984", "id": "reaction_10037927", "reactome": "R-BTA-140806", "name": "SERPINC1 binds SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037925", "species_9693058" ], "products": [ "species_10037919" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071014", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10055529": { "compartment": "compartment_7660", "id": "reaction_10055529", "reactome": "R-BTA-983218", "name": "RAD51B:RAD51C binds single-stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29868", "species_10055525" ], "products": [ "species_10055527" ], "modifiers": [], "additional_components": [ "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "species_29868" ] }, "reaction_10055995": { "compartment": "compartment_7660", "id": "reaction_10055995", "reactome": "R-BTA-1008200", "name": "NFE2 binds the beta globin locus control region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055991", "species_1008228" ], "products": [ "species_10055993" ], "modifiers": [], "additional_components": [ "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479", "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479" ] }, "reaction_10055933": { "compartment": "compartment_70101", "id": "reaction_10055933", "reactome": "R-BTA-997237", "name": "SH2B proteins bind JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055926", "species_10055929" ], "products": [ "species_10055931" ], "modifiers": [], "additional_components": [ "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236", "ENSBTAT00000015986", "E1BCP6", "ENSBTAT00000015986", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10055870": { "compartment": "compartment_7660", "id": "reaction_10055870", "reactome": "R-BTA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055855", "species_10055866" ], "products": [ "species_10055868" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008198", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F2Z4J7", "ENSBTAT00000008198" ] }, "reaction_10055649": { "compartment": "compartment_7660", "id": "reaction_10055649", "reactome": "R-BTA-983285", "name": "RAD51B binds RAD51C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10055519" ], "products": [ "species_10055525" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000025252", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10055920": { "compartment": "compartment_7660", "id": "reaction_10055920", "reactome": "R-BTA-996755", "name": "ZFPM proteins bind GATA proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055890", "species_10055916" ], "products": [ "species_10055918" ], "modifiers": [], "additional_components": [ "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161" ] }, "reaction_10056002": { "compartment": "compartment_5460", "id": "reaction_10056002", "reactome": "R-BTA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10055999", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022789" ] }, "reaction_10055847": { "compartment": "compartment_17906", "id": "reaction_10055847", "reactome": "R-BTA-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055843" ], "products": [ "species_10055845" ], "modifiers": [], "additional_components": [ "D7GLD0", "ENSBTAT00000080672", "D7GLD0", "ENSBTAT00000080672" ] }, "reaction_10085753": { "compartment": "compartment_876", "id": "reaction_10085753", "reactome": "R-BTA-8870732", "name": "PSGs bind proteoglycans and TGF-beta1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085749", "species_10085701" ], "products": [ "species_10085751" ], "modifiers": [], "additional_components": [ "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125" ] }, "reaction_10043323": { "compartment": "compartment_876", "id": "reaction_10043323", "reactome": "R-BTA-202709", "name": "JAM2 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319" ], "products": [ "species_10043321" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043355": { "compartment": "compartment_876", "id": "reaction_10043355", "reactome": "R-BTA-202717", "name": "Heterodimerization of CEACAMs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043351" ], "products": [ "species_10043353" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069303", "A0A3Q1MQ27", "ENSBTAT00000069303" ] }, "reaction_10043375": { "compartment": "compartment_876", "id": "reaction_10043375", "reactome": "R-BTA-202722", "name": "CD48 binds CD244", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043367", "species_10043371" ], "products": [ "species_10043373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014924", "ENSBTAT00000084280", "A0A3Q1LFU5", "ENSBTAT00000084280", "Q2KHZ6", "ENSBTAT00000014924" ] }, "reaction_10044024": { "compartment": "compartment_70101", "id": "reaction_10044024", "reactome": "R-BTA-210283", "name": "Interaction of PECAM-1 and PLC gamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043197" ], "products": [ "species_10044022" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044030": { "compartment": "compartment_876", "id": "reaction_10044030", "reactome": "R-BTA-210285", "name": "Trans-homophilic interaction of PECAM-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044026" ], "products": [ "species_10044028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044034": { "compartment": "compartment_70101", "id": "reaction_10044034", "reactome": "R-BTA-210290", "name": "Interaction of PECAM-1 and SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043216", "species_10044014" ], "products": [ "species_10044032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077857", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10044039": { "compartment": "compartment_70101", "id": "reaction_10044039", "reactome": "R-BTA-210291", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044028" ], "products": [ "species_10044036", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10043393": { "compartment": "compartment_876", "id": "reaction_10043393", "reactome": "R-BTA-202724", "name": "P-selectin binds P-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043379", "species_10043389" ], "products": [ "species_10043391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029578", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10043363": { "compartment": "compartment_876", "id": "reaction_10043363", "reactome": "R-BTA-202721", "name": "JAM2 binds JAM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319", "species_10043359" ], "products": [ "species_10043361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043347": { "compartment": "compartment_876", "id": "reaction_10043347", "reactome": "R-BTA-202714", "name": "CD58 binds CD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043343", "species_10043339" ], "products": [ "species_10043345" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084844", "ENSBTAT00000022936", "Q148M9", "ENSBTAT00000022936", "F6PZJ9", "ENSBTAT00000084844" ] }, "reaction_10043397": { "compartment": "compartment_876", "id": "reaction_10043397", "reactome": "R-BTA-202731", "name": "JAM3 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043359" ], "products": [ "species_10043395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263" ] }, "reaction_10043335": { "compartment": "compartment_876", "id": "reaction_10043335", "reactome": "R-BTA-202713", "name": "CD84 homodimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043331" ], "products": [ "species_10043333" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053223", "F1N7U9", "ENSBTAT00000053223" ] }, "reaction_10066263": { "compartment": "compartment_876", "id": "reaction_10066263", "reactome": "R-BTA-2870221", "name": "E-selectin binds E-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066259", "species_10043387" ], "products": [ "species_10066261" ], "modifiers": [], "additional_components": [ "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578", "ENSBTAT00000009612", "P98107", "ENSBTAT00000009612", "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10038329": { "compartment": "compartment_984", "id": "reaction_10038329", "reactome": "R-BTA-158893", "name": "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038260", "species_10038324" ], "products": [ "species_10038326" ], "modifiers": [ [ "species_10038324", "catalyst" ] ], "additional_components": [ "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793", "P28800", "ENSBTAT00000027793", "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793" ] }, "reaction_10038285": { "compartment": "compartment_984", "id": "reaction_10038285", "reactome": "R-BTA-158750", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038272" ], "products": [ "species_10038260", "species_10038267" ], "modifiers": [ [ "species_10038272", "catalyst" ], [ "species_10038283", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "P60902", "ENSBTAT00000020150", "P04272", "ENSBTAT00000012655" ] }, "reaction_10038303": { "compartment": "compartment_984", "id": "reaction_10038303", "reactome": "R-BTA-158795", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267", "species_10038296" ], "products": [ "species_10038298" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038270": { "compartment": "compartment_984", "id": "reaction_10038270", "reactome": "R-BTA-158747", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267" ], "products": [ "species_10038248" ], "modifiers": [ [ "species_10038260", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038288": { "compartment": "compartment_984", "id": "reaction_10038288", "reactome": "R-BTA-158756", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038248" ], "products": [ "species_10038254" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038307": { "compartment": "compartment_984", "id": "reaction_10038307", "reactome": "R-BTA-158800", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038296", "species_10038248" ], "products": [ "species_10038305" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038290": { "compartment": "compartment_984", "id": "reaction_10038290", "reactome": "R-BTA-158781", "name": "crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_157771", "species_10038265" ], "products": [ "species_10038267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642" ] }, "reaction_10038292": { "compartment": "compartment_984", "id": "reaction_10038292", "reactome": "R-BTA-158784", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038267" ], "products": [ "species_10038272" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038263": { "compartment": "compartment_984", "id": "reaction_10038263", "reactome": "R-BTA-158744", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038254" ], "products": [ "species_10038260", "species_10038248" ], "modifiers": [ [ "species_10038254", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10057598": { "compartment": "compartment_984", "id": "reaction_10057598", "reactome": "R-BTA-1297333", "name": "Association of Acrosin Heavy and Light Chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057594", "species_10057592" ], "products": [ "species_10057596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "G5E5C6", "ENSBTAT00000013434" ] }, "reaction_10057605": { "compartment": "compartment_984", "id": "reaction_10057605", "reactome": "R-BTA-1297354", "name": "Acrosin Cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057602" ], "products": [ "species_10057594", "species_10057592" ], "modifiers": [ [ "species_10057602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434" ] }, "reaction_10091211": { "compartment": "compartment_7660", "id": "reaction_10091211", "reactome": "R-BTA-9629195", "name": "NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091207", "species_10091201" ], "products": [ "species_10091209" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10091566": { "compartment": "compartment_70101", "id": "reaction_10091566", "reactome": "R-BTA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091562" ], "products": [ "species_10091564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010226", "ENSBTAT00000010226" ] }, "reaction_10035854": { "compartment": "compartment_7660", "id": "reaction_10035854", "reactome": "R-BTA-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10035850" ], "products": [ "species_10035852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016732", "F1MUY9", "ENSBTAT00000016732" ] }, "reaction_10036760": { "compartment": "compartment_7660", "id": "reaction_10036760", "reactome": "R-BTA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036755" ], "products": [ "species_10036757", "species_110242" ], "modifiers": [ [ "species_10036755", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10091240": { "compartment": "compartment_7660", "id": "reaction_10091240", "reactome": "R-BTA-9629492", "name": "NEIL3 cleaves spiroiminodihydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091237" ], "products": [ "species_9629439", "species_10091230" ], "modifiers": [ [ "species_10091237", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036782": { "compartment": "compartment_7660", "id": "reaction_10036782", "reactome": "R-BTA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036777" ], "products": [ "species_5635947", "species_10036779" ], "modifiers": [ [ "species_10036777", "catalyst" ] ], "additional_components": [ "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928" ] }, "reaction_10036798": { "compartment": "compartment_7660", "id": "reaction_10036798", "reactome": "R-BTA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036795" ], "products": [ "species_10036788", "species_110249" ], "modifiers": [ [ "species_10036795", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091233": { "compartment": "compartment_7660", "id": "reaction_10091233", "reactome": "R-BTA-9629470", "name": "NEIL3 cleaves 5-guanidinohydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091226" ], "products": [ "species_10091230", "species_9629218" ], "modifiers": [ [ "species_10091226", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036805": { "compartment": "compartment_7660", "id": "reaction_10036805", "reactome": "R-BTA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036802" ], "products": [ "species_10036788", "species_29850" ], "modifiers": [ [ "species_10036802", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10036791": { "compartment": "compartment_7660", "id": "reaction_10036791", "reactome": "R-BTA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036786" ], "products": [ "species_10036788", "species_30947" ], "modifiers": [ [ "species_10036786", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091222": { "compartment": "compartment_7660", "id": "reaction_10091222", "reactome": "R-BTA-9629216", "name": "NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091209" ], "products": [ "species_10091219", "species_9629218" ], "modifiers": [ [ "species_10091209", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10072876": { "compartment": "compartment_7660", "id": "reaction_10072876", "reactome": "R-BTA-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072868", "species_10072872" ], "products": [ "species_10072874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000131", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10072883": { "compartment": "compartment_7660", "id": "reaction_10072883", "reactome": "R-BTA-5653786", "name": "USP43 deISGylates ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10072874" ], "products": [ "species_10072868", "species_10072880", "species_10072878" ], "modifiers": [ [ "species_10072874", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131", "ENSBTAT00000000131", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10073302": { "compartment": "compartment_7660", "id": "reaction_10073302", "reactome": "R-BTA-5655193", "name": "KIAA0101 double monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073294", "species_10036828" ], "products": [ "species_10073300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054209", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q5E9B2", "ENSBTAT00000054209" ] }, "reaction_10044547": { "compartment": "compartment_984", "id": "reaction_10044547", "reactome": "R-BTA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10044544", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024018" ] }, "reaction_10088982": { "compartment": "compartment_984", "id": "reaction_10088982", "reactome": "R-BTA-8980228", "name": "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088979", "catalyst" ] ], "additional_components": [ "A0A3Q1LR40", "ENSBTAT00000075023" ] }, "reaction_10084509": { "compartment": "compartment_876", "id": "reaction_10084509", "reactome": "R-BTA-8857928", "name": "GPIHBP1 binds HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077472", "species_10077480" ], "products": [ "species_10077482" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071232", "species_1678620", "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232" ] }, "reaction_10077487": { "compartment": "compartment_876", "id": "reaction_10077487", "reactome": "R-BTA-6784676", "name": "PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077482" ], "products": [ "species_10077476", "species_10077472", "species_1678620" ], "modifiers": [ [ "species_10077484", "catalyst" ] ], "additional_components": [ "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232", "ENSBTAT00000017086", "ENSBTAT00000071232", "ENSBTAT00000077745" ] }, "reaction_10077489": { "compartment": "compartment_984", "id": "reaction_10077489", "reactome": "R-BTA-6784861", "name": "HSPG binds LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077478", "species_1678620" ], "products": [ "species_10077480" ], "modifiers": [], "additional_components": [ "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086" ] }, "reaction_10077593": { "compartment": "compartment_7660", "id": "reaction_10077593", "reactome": "R-BTA-6785607", "name": "FANCM binds FAAP24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077506", "species_10077502" ], "products": [ "species_10077508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071085", "ENSBTAT00000065656", "Q2KHY5", "ENSBTAT00000065656", "A0A3Q1MT39", "ENSBTAT00000071085" ] }, "reaction_10077625": { "compartment": "compartment_7660", "id": "reaction_10077625", "reactome": "R-BTA-6785732", "name": "DNA nucleases bind monoubiquitinated ID2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036659", "species_10077619", "species_10077582", "species_10075163", "species_10077609" ], "products": [ "species_10077623" ], "modifiers": [], "additional_components": [ "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "E1BN11", "ENSBTAT00000026896", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "ENSBTAT00000085708", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BN11", "ENSBTAT00000026896", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "A0A3Q1MJE2", "ENSBTAT00000085708" ] }, "reaction_10077591": { "compartment": "compartment_7660", "id": "reaction_10077591", "reactome": "R-BTA-6785361", "name": "Monoubiquitination of FANCD2:FANCI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077569", "species_10036828" ], "products": [ "species_10077588", "species_10077582" ], "modifiers": [ [ "species_10077569", "catalyst" ] ], "additional_components": [ "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467" ] }, "reaction_10035372": { "compartment": "compartment_5460", "id": "reaction_10035372", "reactome": "R-BTA-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10035369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005088" ] }, "reaction_10035363": { "compartment": "compartment_5460", "id": "reaction_10035363", "reactome": "R-BTA-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_73909", "species_29362" ], "products": [ "species_113526", "species_73911" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10049883": { "compartment": "compartment_70101", "id": "reaction_10049883", "reactome": "R-BTA-446322", "name": "PARVA associates with Paxillin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049875" ], "products": [ "species_10049881" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000024101", "F1MFD1", "ENSBTAT00000024101", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10049312": { "compartment": "compartment_70101", "id": "reaction_10049312", "reactome": "R-BTA-432946", "name": "PARVB/Affixin interacts with alpha PIX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049308", "species_10048105" ], "products": [ "species_10049310" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084501", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1M7B6", "ENSBTAT00000084501" ] }, "reaction_10049891": { "compartment": "compartment_70101", "id": "reaction_10049891", "reactome": "R-BTA-446372", "name": "Association of PARVA with TESK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049887" ], "products": [ "species_10049889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000082961", "A0A3Q1MET9", "ENSBTAT00000082961", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10038942": { "compartment": "compartment_7660", "id": "reaction_10038942", "reactome": "R-BTA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10035753" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083979" ] }, "reaction_10036844": { "compartment": "compartment_7660", "id": "reaction_10036844", "reactome": "R-BTA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036840", "species_10036809" ], "products": [ "species_10036842" ], "modifiers": [], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000066497", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10036853": { "compartment": "compartment_7660", "id": "reaction_10036853", "reactome": "R-BTA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10036842" ], "products": [ "species_10036850" ], "modifiers": [ [ "species_10036842", "catalyst" ] ], "additional_components": [ "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073275": { "compartment": "compartment_7660", "id": "reaction_10073275", "reactome": "R-BTA-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073270", "species_29358" ], "products": [ "species_113582", "species_10073272", "species_10036857" ], "modifiers": [ [ "species_10073270", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "A5D979", "ENSBTAT00000008030", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10073290": { "compartment": "compartment_7660", "id": "reaction_10073290", "reactome": "R-BTA-5655170", "name": "RCHY1 monoubiquitinates POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10073277" ], "products": [ "species_10073287", "species_10036867" ], "modifiers": [ [ "species_10073277", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "ENSBTAT00000009461", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036879": { "compartment": "compartment_7660", "id": "reaction_10036879", "reactome": "R-BTA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036863", "species_29604" ], "products": [ "species_10036876", "species_113541" ], "modifiers": [ [ "species_10036863", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073279": { "compartment": "compartment_7660", "id": "reaction_10073279", "reactome": "R-BTA-5655142", "name": "RCHY1 binds POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036867", "species_10036857" ], "products": [ "species_10073277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009461", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036869": { "compartment": "compartment_7660", "id": "reaction_10036869", "reactome": "R-BTA-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036861", "species_10036857" ], "products": [ "species_10036863" ], "modifiers": [ [ "species_10036867", "inhibitor" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000009461" ] }, "reaction_10036886": { "compartment": "compartment_7660", "id": "reaction_10036886", "reactome": "R-BTA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10036876" ], "products": [ "species_10036883", "species_113541" ], "modifiers": [ [ "species_10036876", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073254": { "compartment": "compartment_7660", "id": "reaction_10073254", "reactome": "R-BTA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073250", "species_10036883" ], "products": [ "species_10073252" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008030", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030" ] }, "reaction_10090392": { "compartment": "compartment_70101", "id": "reaction_10090392", "reactome": "R-BTA-9020274", "name": "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9025012" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090394": { "compartment": "compartment_70101", "id": "reaction_10090394", "reactome": "R-BTA-9020275", "name": "ALOX15 oxidises DHA to 17(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024012" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090462": { "compartment": "compartment_70101", "id": "reaction_10090462", "reactome": "R-BTA-9024881", "name": "ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024012" ], "products": [ "species_29364", "species_9024873" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090384": { "compartment": "compartment_70101", "id": "reaction_10090384", "reactome": "R-BTA-9020261", "name": "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024522" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090464": { "compartment": "compartment_70101", "id": "reaction_10090464", "reactome": "R-BTA-9024983", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_29364", "species_9025001" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090458": { "compartment": "compartment_70101", "id": "reaction_10090458", "reactome": "R-BTA-9024766", "name": "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024764", "species_29360" ], "products": [ "species_9024799", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "CHEBI:132797", "CHEBI:132800", "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090390": { "compartment": "compartment_70101", "id": "reaction_10090390", "reactome": "R-BTA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090388": { "compartment": "compartment_70101", "id": "reaction_10090388", "reactome": "R-BTA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10062377": { "compartment": "compartment_984", "id": "reaction_10062377", "reactome": "R-BTA-2002440", "name": "Removal of fibrillar collagen C-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062335" ], "products": [ "species_10058697" ], "modifiers": [ [ "species_10062368", "catalyst" ], [ "species_10062375", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "F1N0X6", "ENSBTAT00000007834", "Q2HJB6", "ENSBTAT00000027347", "F1MKP1", "ENSBTAT00000021330" ] }, "reaction_10061787": { "compartment": "compartment_17957", "id": "reaction_10061787", "reactome": "R-BTA-1980233", "name": "Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_10061734", "species_1650779" ], "products": [ "species_1650769", "species_159751", "species_10061784" ], "modifiers": [ [ "species_10061734", "catalyst" ] ], "additional_components": [ "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067" ] }, "reaction_10060187": { "compartment": "compartment_17957", "id": "reaction_10060187", "reactome": "R-BTA-1614460", "name": "Dimerization of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060183" ], "products": [ "species_10060185" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087626": { "compartment": "compartment_17957", "id": "reaction_10087626", "reactome": "R-BTA-8948228", "name": "COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061921", "species_10061791" ], "products": [ "species_10061923" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10062058": { "compartment": "compartment_17957", "id": "reaction_10062058", "reactome": "R-BTA-1981120", "name": "Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1981137", "species_10061923" ], "products": [ "species_10062055", "species_158602" ], "modifiers": [ [ "species_10061923", "catalyst" ] ], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10087628": { "compartment": "compartment_17957", "id": "reaction_10087628", "reactome": "R-BTA-8948231", "name": "COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062055" ], "products": [ "species_10062053", "species_10061791" ], "modifiers": [], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "ENSBTAT00000050322" ] }, "reaction_10060191": { "compartment": "compartment_17957", "id": "reaction_10060191", "reactome": "R-BTA-1614461", "name": "Tetramerization of procollagen VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060185" ], "products": [ "species_10060189" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10064337": { "compartment": "compartment_17957", "id": "reaction_10064337", "reactome": "R-BTA-2152276", "name": "Secretion of transmembrane collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062852" ], "products": [ "species_10064335" ], "modifiers": [], "additional_components": [ "F1MSJ7", "ENSBTAT00000017548", "F6RND5", "ENSBTAT00000039811", "E1BKJ9", "ENSBTAT00000044319", "F1MSJ7", "ENSBTAT00000017548", "E1BKJ9", "ENSBTAT00000044319", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10062352": { "compartment": "compartment_984", "id": "reaction_10062352", "reactome": "R-BTA-2002428", "name": "Removal of fibrillar collagen N-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062205" ], "products": [ "species_10062335" ], "modifiers": [ [ "species_10062349", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "E1BC50", "ENSBTAT00000061447", "E1BFV4", "ENSBTAT00000028224" ] }, "reaction_10063799": { "compartment": "compartment_17957", "id": "reaction_10063799", "reactome": "R-BTA-2089971", "name": "Secretion of collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063637" ], "products": [ "species_10063797", "species_10062846" ], "modifiers": [], "additional_components": [ "Q2KJH6", "ENSBTAT00000083385", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "A0A3Q1M646", "ENSBTAT00000081723", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052", "P02459", "ENSBTAT00000017505", "F1MSJ7", "ENSBTAT00000017548", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "A0A3Q1M0N0", "ENSBTAT00000072268", "A0A3Q1MQC5", "ENSBTAT00000074238", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1M0N0", "ENSBTAT00000072268", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "ENSBTAT00000083385" ] }, "reaction_10064491": { "compartment": "compartment_70101", "id": "reaction_10064491", "reactome": "R-BTA-2161775", "name": "ALOX12 oxidises LTA4 to LXA4/B4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9032038", "species_29368" ], "products": [ "species_2161856" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:6499", "species_2161759", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10064500": { "compartment": "compartment_70101", "id": "reaction_10064500", "reactome": "R-BTA-2161779", "name": "LXA4 is oxidised to 15k-LXA4 by HPGD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161759", "species_29360" ], "products": [ "species_70106", "species_2142761", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10065691": { "compartment": "compartment_984", "id": "reaction_10065691", "reactome": "R-BTA-2466106", "name": "BGN binds Collagen types I, VI, (IX)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282", "species_10062553" ], "products": [ "species_10065689" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000047242", "P21809", "ENSBTAT00000047242", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10065300": { "compartment": "compartment_984", "id": "reaction_10065300", "reactome": "R-BTA-2327909", "name": "DCN binds collagen I, II, III, VI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065296", "species_10065294" ], "products": [ "species_10065298" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000004562", "P21793", "ENSBTAT00000004562", "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10064953": { "compartment": "compartment_984", "id": "reaction_10064953", "reactome": "R-BTA-2213201", "name": "Formation of collagen fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058703" ], "products": [ "species_10064951" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10064959": { "compartment": "compartment_984", "id": "reaction_10064959", "reactome": "R-BTA-2213207", "name": "Formation of collagen networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064955" ], "products": [ "species_10064957" ], "modifiers": [], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10058705": { "compartment": "compartment_984", "id": "reaction_10058705", "reactome": "R-BTA-1474266", "name": "Formation of collagen fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058697" ], "products": [ "species_10058703" ], "modifiers": [], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10065929": { "compartment": "compartment_984", "id": "reaction_10065929", "reactome": "R-BTA-2559639", "name": "Collagen type IV sulfilimine cross-linking by peroxidasin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_351629" ], "products": [ "species_10065920" ], "modifiers": [ [ "species_10065926", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "CHEBI:15858", "A0A3Q1LMN6", "ENSBTAT00000073028" ] }, "reaction_10035464": { "compartment": "compartment_70101", "id": "reaction_10035464", "reactome": "R-BTA-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_83956" ], "products": [ "species_31633", "species_30064" ], "modifiers": [ [ "species_10035461", "catalyst" ] ], "additional_components": [ "species_29426", "F1MLX9", "ENSBTAT00000015339" ] }, "reaction_10088571": { "compartment": "compartment_70101", "id": "reaction_10088571", "reactome": "R-BTA-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109327", "species_29356" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10088568", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026530" ] }, "reaction_10035453": { "compartment": "compartment_70101", "id": "reaction_10035453", "reactome": "R-BTA-74242", "name": "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500172" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036207": { "compartment": "compartment_984", "id": "reaction_10036207", "reactome": "R-BTA-109278", "name": "NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500101" ], "products": [ "species_500104", "species_109277" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_2509792", "species_76577", "species_113578", "species_109386", "CHEBI:17596", "CHEBI:16750", "species_83909", "CHEBI:17256", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035455": { "compartment": "compartment_70101", "id": "reaction_10035455", "reactome": "R-BTA-74249", "name": "(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500245" ], "products": [ "species_83956", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:16750", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036238": { "compartment": "compartment_70101", "id": "reaction_10036238", "reactome": "R-BTA-109415", "name": "AMP + H2O => adenosine + orthophosphate [NT5C1B]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29372", "species_83909" ], "modifiers": [ [ "species_10036235", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006950" ] }, "reaction_10036256": { "compartment": "compartment_70101", "id": "reaction_10036256", "reactome": "R-BTA-109470", "name": "(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500120", "species_29356" ], "products": [ "species_29372", "species_500118" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "species_2509792", "species_2509805", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "CHEBI:17596", "CHEBI:16750", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10036231": { "compartment": "compartment_70101", "id": "reaction_10036231", "reactome": "R-BTA-109387", "name": "(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500125" ], "products": [ "species_29372", "species_500124" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_76577", "species_2509792", "species_2509805", "species_109386", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "species_83909", "CHEBI:17256", "CHEBI:17596", "CHEBI:16750", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10053044": { "compartment": "compartment_70101", "id": "reaction_10053044", "reactome": "R-BTA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053039", "species_113592" ], "products": [ "species_10053041", "species_29370" ], "modifiers": [ [ "species_10053039", "catalyst" ] ], "additional_components": [ "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10090377": { "compartment": "compartment_70101", "id": "reaction_10090377", "reactome": "R-BTA-9018880", "name": "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9022921" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "species_9023653", "species_9020583", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090440": { "compartment": "compartment_70101", "id": "reaction_10090440", "reactome": "R-BTA-9023968", "name": "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9022660", "species_29360" ], "products": [ "species_9023963", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090396": { "compartment": "compartment_70101", "id": "reaction_10090396", "reactome": "R-BTA-9020610", "name": "ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9020474" ], "products": [ "species_9022679" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090374": { "compartment": "compartment_70101", "id": "reaction_10090374", "reactome": "R-BTA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090379": { "compartment": "compartment_70101", "id": "reaction_10090379", "reactome": "R-BTA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090382": { "compartment": "compartment_70101", "id": "reaction_10090382", "reactome": "R-BTA-9018907", "name": "ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023651", "species_29368" ], "products": [ "species_9023644" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10065866": { "compartment": "compartment_876", "id": "reaction_10065866", "reactome": "R-BTA-2534359", "name": "CatSper Channel Mediated Calcium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10065861", "catalyst" ] ], "additional_components": [ "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065884": { "compartment": "compartment_876", "id": "reaction_10065884", "reactome": "R-BTA-2534378", "name": "Hv1 Mediated H+ Permeability", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1132304" ], "products": [ "species_351626" ], "modifiers": [ [ "species_10065881", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10065886": { "compartment": "compartment_984", "id": "reaction_10065886", "reactome": "R-BTA-2534388", "name": "Progesterone Activation Of CatSper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065863", "species_1449667" ], "products": [ "species_10065861" ], "modifiers": [], "additional_components": [ "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586", "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065875": { "compartment": "compartment_876", "id": "reaction_10065875", "reactome": "R-BTA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10065872", "catalyst" ] ], "additional_components": [ "A0A3S5ZP59", "ENSBTAT00000038859" ] }, "reaction_10076856": { "compartment": "compartment_984", "id": "reaction_10076856", "reactome": "R-BTA-5696131", "name": "AOC1 deaminates Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_390899", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696128" ], "modifiers": [ [ "species_10076853", "catalyst" ] ], "additional_components": [ "Q3MHQ1", "ENSBTAT00000007133", "species_74016", "CHEBI:28694" ] }, "reaction_10077496": { "compartment": "compartment_70101", "id": "reaction_10077496", "reactome": "R-BTA-6784959", "name": "BPHL hydrolyses VACV to ACV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6784964" ], "products": [ "species_29702", "species_561052" ], "modifiers": [ [ "species_10077493", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008368" ] }, "reaction_10076475": { "compartment": "compartment_12045", "id": "reaction_10076475", "reactome": "R-BTA-5694077", "name": "EPHX1 hydrates BaP4,5O to BaP4,5-DHD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694080" ], "products": [ "species_5694091" ], "modifiers": [ [ "species_10076472", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083641" ] }, "reaction_10076863": { "compartment": "compartment_984", "id": "reaction_10076863", "reactome": "R-BTA-5696146", "name": "AOC2 deaminates TYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5696181", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696178" ], "modifiers": [ [ "species_10076860", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042833" ] }, "reaction_10076884": { "compartment": "compartment_984", "id": "reaction_10076884", "reactome": "R-BTA-5696183", "name": "AOC3 deaminates BZAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_352327", "species_5696148" ], "products": [ "species_351626", "species_5696154", "species_2022135", "species_351629" ], "modifiers": [ [ "species_10076881", "catalyst" ] ], "additional_components": [ "Q9TTK6", "ENSBTAT00000081083", "A0A452DHX8", "ENSBTAT00000001383", "Q29437", "ENSBTAT00000081083", "species_74016", "CHEBI:28694" ] }, "reaction_10076375": { "compartment": "compartment_17957", "id": "reaction_10076375", "reactome": "R-BTA-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693702" ], "products": [ "species_156540", "species_5693711", "species_5693712" ], "modifiers": [ [ "species_10076372", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461", "F1MU22", "ENSBTAT00000032343" ] }, "reaction_10086550": { "compartment": "compartment_70101", "id": "reaction_10086550", "reactome": "R-BTA-8937419", "name": "CBR3 reduces DOX to DOXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8937424", "species_29364" ], "products": [ "species_29366", "species_8937418" ], "modifiers": [ [ "species_10086547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024873" ] }, "reaction_10044524": { "compartment": "compartment_17960", "id": "reaction_10044524", "reactome": "R-BTA-217255", "name": "FMO1:FAD N-oxidises TAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_159154" ], "products": [ "species_113519", "species_113564", "species_217269" ], "modifiers": [ [ "species_10044521", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1M207", "ENSBTAT00000079411" ] }, "reaction_10044533": { "compartment": "compartment_17960", "id": "reaction_10044533", "reactome": "R-BTA-217258", "name": "FMO2:FAD:Mg2+ S-oxidises MTZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_217315" ], "products": [ "species_113519", "species_113564", "species_217320" ], "modifiers": [ [ "species_10044530", "catalyst" ] ], "additional_components": [ "species_29926", "species_113596", "G5E540", "ENSBTAT00000003873" ] }, "reaction_10034175": { "compartment": "compartment_70101", "id": "reaction_10034175", "reactome": "R-BTA-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29510", "species_29360" ], "products": [ "species_70106", "species_29416", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10034206": { "compartment": "compartment_70101", "id": "reaction_10034206", "reactome": "R-BTA-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_29510", "species_73473" ], "modifiers": [ [ "species_10034203", "catalyst" ] ], "additional_components": [ "species_29426", "E1BBW9", "ENSBTAT00000020879", "F1MFZ4", "ENSBTAT00000003769", "F1MZN9", "ENSBTAT00000009191", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10050160": { "compartment": "compartment_5460", "id": "reaction_10050160", "reactome": "R-BTA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10050157", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086374" ] }, "reaction_10076144": { "compartment": "compartment_70101", "id": "reaction_10076144", "reactome": "R-BTA-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_5692249", "species_70106", "species_73473" ], "modifiers": [ [ "species_10076141", "catalyst" ] ], "additional_components": [ "Q3ZC42", "ENSBTAT00000021304", "species_29426" ] }, "reaction_10034215": { "compartment": "compartment_5460", "id": "reaction_10034215", "reactome": "R-BTA-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113532", "species_113526", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113539" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10034231": { "compartment": "compartment_70101", "id": "reaction_10034231", "reactome": "R-BTA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10034228", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078990" ] }, "reaction_10075404": { "compartment": "compartment_12045", "id": "reaction_10075404", "reactome": "R-BTA-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5689006" ], "products": [ "species_5689001", "species_5688995" ], "modifiers": [ [ "species_10075401", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015373" ] }, "reaction_10086543": { "compartment": "compartment_7660", "id": "reaction_10086543", "reactome": "R-BTA-8937177", "name": "AHR:TCDD binds ARNT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035973", "species_10035969" ], "products": [ "species_10035975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016391", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10086469": { "compartment": "compartment_70101", "id": "reaction_10086469", "reactome": "R-BTA-8936519", "name": "NQO2:FAD dimer reduces quinones to hydroquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936516", "species_8936520" ], "products": [ "species_8936514", "species_8936507" ], "modifiers": [ [ "species_10086466", "catalyst" ], [ "species_209934", "inhibitor" ], [ "species_1130942", "inhibitor" ] ], "additional_components": [ "Q3SZT2", "ENSBTAT00000072063", "species_113596" ] }, "reaction_10077734": { "compartment": "compartment_70101", "id": "reaction_10077734", "reactome": "R-BTA-6786190", "name": "CMBL hydrolyses OM to OLMS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6786175" ], "products": [ "species_6786194", "species_6786179" ], "modifiers": [ [ "species_10077731", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072469" ] }, "reaction_10041241": { "compartment": "compartment_984", "id": "reaction_10041241", "reactome": "R-BTA-192434", "name": "Digestion of diacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_174675" ], "products": [ "species_6814795", "species_174602" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10088973": { "compartment": "compartment_984", "id": "reaction_10088973", "reactome": "R-BTA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088970", "catalyst" ] ], "additional_components": [] }, "reaction_10041239": { "compartment": "compartment_984", "id": "reaction_10041239", "reactome": "R-BTA-192422", "name": "Digestion of triacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10076274": { "compartment": "compartment_876", "id": "reaction_10076274", "reactome": "R-BTA-5693373", "name": "DDAH1,2 hydrolyses ADMA to DMA and L-Cit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693375" ], "products": [ "species_5693410", "species_29968" ], "modifiers": [ [ "species_10076271", "catalyst" ] ], "additional_components": [ "P56965", "ENSBTAT00000049235", "Q3SX44", "ENSBTAT00000085909" ] }, "reaction_10040617": { "compartment": "compartment_984", "id": "reaction_10040617", "reactome": "R-BTA-189062", "name": "lactose + H2O => D-glucose + D-galactose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188973", "species_109276" ], "products": [ "species_70115", "species_188995" ], "modifiers": [ [ "species_10040614", "catalyst" ] ], "additional_components": [ "E1BK89", "ENSBTAT00000020185" ] }, "reaction_10040872": { "compartment": "compartment_984", "id": "reaction_10040872", "reactome": "R-BTA-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040620": { "compartment": "compartment_984", "id": "reaction_10040620", "reactome": "R-BTA-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_189049", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040608": { "compartment": "compartment_984", "id": "reaction_10040608", "reactome": "R-BTA-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189108" ], "products": [ "species_191103", "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040595": { "compartment": "compartment_984", "id": "reaction_10040595", "reactome": "R-BTA-188979", "name": "Digestion of linear starch (amylose) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189075" ], "products": [ "species_191103", "species_188986" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10040866": { "compartment": "compartment_984", "id": "reaction_10040866", "reactome": "R-BTA-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10073378": { "compartment": "compartment_984", "id": "reaction_10073378", "reactome": "R-BTA-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040629": { "compartment": "compartment_984", "id": "reaction_10040629", "reactome": "R-BTA-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040868": { "compartment": "compartment_984", "id": "reaction_10040868", "reactome": "R-BTA-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040870": { "compartment": "compartment_984", "id": "reaction_10040870", "reactome": "R-BTA-191114", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189071" ], "products": [ "species_191103", "species_188986", "species_189108" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10086435": { "compartment": "compartment_984", "id": "reaction_10086435", "reactome": "R-BTA-8936214", "name": "GUCY2C trimer binds GUCA2A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086431", "species_10086425" ], "products": [ "species_10086433" ], "modifiers": [], "additional_components": [ "F1N5B2", "ENSBTAT00000026286", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "F1N5B2", "ENSBTAT00000026286" ] }, "reaction_10036917": { "compartment": "compartment_7660", "id": "reaction_10036917", "reactome": "R-BTA-111438", "name": "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036044", "species_10036072" ], "products": [ "species_10036911" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10039865": { "compartment": "compartment_70101", "id": "reaction_10039865", "reactome": "R-BTA-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_111707", "species_113592" ], "products": [ "species_29372", "species_174393", "species_29370" ], "modifiers": [ [ "species_10039862", "catalyst" ] ], "additional_components": [ "A0A3Q1MN33", "ENSBTAT00000081594", "Q2T9Y6", "ENSBTAT00000026855" ] }, "reaction_10087515": { "compartment": "compartment_876", "id": "reaction_10087515", "reactome": "R-BTA-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1247892" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10077658": { "compartment": "compartment_70101", "id": "reaction_10077658", "reactome": "R-BTA-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247942", "species_1247904" ], "modifiers": [ [ "species_10077655", "catalyst" ] ], "additional_components": [ "A6H738", "ENSBTAT00000013689", "Q0IIH4", "ENSBTAT00000025922" ] }, "reaction_10057079": { "compartment": "compartment_70101", "id": "reaction_10057079", "reactome": "R-BTA-1247922", "name": "GGCT transforms gGluCys to OPRO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393" ], "products": [ "species_111707", "species_1247942" ], "modifiers": [ [ "species_10057076", "catalyst" ] ], "additional_components": [ "Q32LE4", "ENSBTAT00000014010" ] }, "reaction_10075362": { "compartment": "compartment_17927", "id": "reaction_10075362", "reactome": "R-BTA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10075353" ], "products": [ "species_5688281", "species_10037239", "species_5688340" ], "modifiers": [ [ "species_10075359", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q3ZBQ0", "ENSBTAT00000072664", "species_29426" ] }, "reaction_10075350": { "compartment": "compartment_5460", "id": "reaction_10075350", "reactome": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10075337" ], "products": [ "species_5688337", "species_5688274", "species_10075341" ], "modifiers": [ [ "species_10075347", "catalyst" ] ], "additional_components": [ "A0A3Q1MB37", "ENSBTAT00000078990", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "A0A3Q1MB37", "ENSBTAT00000078990", "G5E521", "ENSBTAT00000002648", "species_29426" ] }, "reaction_10072271": { "compartment": "compartment_20699", "id": "reaction_10072271", "reactome": "R-BTA-5617828", "name": "TRIP11:IFT20 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072269" ], "products": [ "species_10072263", "species_10072267" ], "modifiers": [], "additional_components": [ "A0A3Q1MQ84", "ENSBTAT00000084706", "Q58CS6", "ENSBTAT00000084852", "ENSBTAT00000084852", "ENSBTAT00000084706" ] }, "reaction_10058751": { "compartment": "compartment_70101", "id": "reaction_10058751", "reactome": "R-BTA-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058753": { "compartment": "compartment_876", "id": "reaction_10058753", "reactome": "R-BTA-1475025", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1237009" ], "products": [ "species_351626", "species_425425" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058755": { "compartment": "compartment_70101", "id": "reaction_10058755", "reactome": "R-BTA-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058722": { "compartment": "compartment_876", "id": "reaction_10058722", "reactome": "R-BTA-1475017", "name": "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_425425" ], "products": [ "species_109276", "species_1237009" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058772": { "compartment": "compartment_5460", "id": "reaction_10058772", "reactome": "R-BTA-1475028", "name": "Carbonic anhydrase dehydrates bicarbonate (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29896", "species_113529" ], "products": [ "species_113521", "species_29376" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10058774": { "compartment": "compartment_5460", "id": "reaction_10058774", "reactome": "R-BTA-1475032", "name": "Carbonic anhydrase hydrates carbon dioxide (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_29376" ], "products": [ "species_29896", "species_113529" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10040030": { "compartment": "compartment_17957", "id": "reaction_10040030", "reactome": "R-BTA-176059", "name": "GST trimers transfer GS from GSH to luminal substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158543", "species_176065" ], "products": [ "species_176048" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_38987", "CHEBI:29132", "CHEBI:32639", "CHEBI:2505", "CHEBI:35896", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10067425": { "compartment": "compartment_5460", "id": "reaction_10067425", "reactome": "R-BTA-3301943", "name": "GSTK1 dimer transfers GS from GSH to CDNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1655887", "species_3301954" ], "products": [ "species_3301973", "species_3301969" ], "modifiers": [ [ "species_10067422", "catalyst" ] ], "additional_components": [ "F1MRG0", "ENSBTAT00000012969" ] }, "reaction_10040021": { "compartment": "compartment_70101", "id": "reaction_10040021", "reactome": "R-BTA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10040018", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "species_3301954", "CHEBI:30614", "species_3301969", "CHEBI:32639", "CHEBI:34479", "A0A3Q1LMV5", "ENSBTAT00000084460", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425", "E1BJ08", "ENSBTAT00000017435", "Q2NL00", "ENSBTAT00000007403", "A1A4L7", "ENSBTAT00000021896", "A0A3Q1MEZ2", "ENSBTAT00000075831", "A0A3Q1LSN6", "ENSBTAT00000085178", "E1BED9", "ENSBTAT00000005211", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10076133": { "compartment": "compartment_70101", "id": "reaction_10076133", "reactome": "R-BTA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10040185": { "compartment": "compartment_5460", "id": "reaction_10040185", "reactome": "R-BTA-177157", "name": "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_177153" ], "products": [ "species_159448", "species_159450", "species_177137" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10038316": { "compartment": "compartment_70101", "id": "reaction_10038316", "reactome": "R-BTA-158832", "name": "The acetyl group from acetyl-CoA is transferred to the NAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039918": { "compartment": "compartment_70101", "id": "reaction_10039918", "reactome": "R-BTA-174959", "name": "The acetyl group from acetyl-CoA is transferred to the NAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039921": { "compartment": "compartment_70101", "id": "reaction_10039921", "reactome": "R-BTA-174963", "name": "NAT1 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174969", "species_10038314" ], "products": [ "species_10038311", "species_174960" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:45373", "CHEBI:30753", "species_34889", "CHEBI:27565", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:63845", "CHEBI:16395", "CHEBI:63815", "CHEBI:63817", "ENSBTAT00000048506" ] }, "reaction_10039923": { "compartment": "compartment_70101", "id": "reaction_10039923", "reactome": "R-BTA-174967", "name": "NAT2 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174971", "species_10038314" ], "products": [ "species_10038311", "species_174958" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:6030", "species_76424", "species_34889", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:7207", "CHEBI:32643", "CHEBI:16395", "ENSBTAT00000048506" ] }, "reaction_10071722": { "compartment": "compartment_70101", "id": "reaction_10071722", "reactome": "R-BTA-5423664", "name": "CYP3A4,5 hydroxylates AFB1 to AFQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423660", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071719", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071754": { "compartment": "compartment_984", "id": "reaction_10071754", "reactome": "R-BTA-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "CHEBI:78581", "CHEBI:78587", "CHEBI:78579", "CHEBI:78584", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10038060": { "compartment": "compartment_70101", "id": "reaction_10038060", "reactome": "R-BTA-156526", "name": "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_29356", "species_159211", "species_29366" ], "modifiers": [ [ "species_10038057", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071727": { "compartment": "compartment_70101", "id": "reaction_10071727", "reactome": "R-BTA-5423672", "name": "CYP1A2, 3A4 oxidise AFB1 to AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071724", "catalyst" ] ], "additional_components": [ "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10071729": { "compartment": "compartment_12045", "id": "reaction_10071729", "reactome": "R-BTA-5423678", "name": "CYP1A2 hydroxylates AFB1 to AFM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423629", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10071712": { "compartment": "compartment_70101", "id": "reaction_10071712", "reactome": "R-BTA-5423637", "name": "AKR dimers reduce AFBDHO to AFBDOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423727", "species_70106", "species_29364" ], "products": [ "species_29366", "species_5423729" ], "modifiers": [ [ "species_10071709", "catalyst" ] ], "additional_components": [ "F1MZC0", "ENSBTAT00000016300", "F1N6I4", "ENSBTAT00000038217" ] }, "reaction_10071715": { "compartment": "compartment_70101", "id": "reaction_10071715", "reactome": "R-BTA-5423647", "name": "CYP2A13 oxidises AFM1 to AFM1E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423629", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_5423657", "species_29366" ], "modifiers": [ [ "species_10035869", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065779" ] }, "reaction_10071763": { "compartment": "compartment_70101", "id": "reaction_10071763", "reactome": "R-BTA-5433074", "name": "ACY1:Zn2+ dimer hydrolyses mercapturic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490236", "species_29356" ], "products": [ "species_2022890", "species_5490231" ], "modifiers": [ [ "species_10071760", "catalyst" ] ], "additional_components": [ "CHEBI:78580", "CHEBI:78585", "CHEBI:78583", "CHEBI:78578", "species_29426", "F1MR63", "ENSBTAT00000024787" ] }, "reaction_10071717": { "compartment": "compartment_70101", "id": "reaction_10071717", "reactome": "R-BTA-5423653", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5423723" ], "products": [ "species_5423730" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_5423663", "CHEBI:78581", "CHEBI:78587", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10074761": { "compartment": "compartment_70101", "id": "reaction_10074761", "reactome": "R-BTA-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074753", "species_10074751" ], "products": [ "species_10074755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "ENSBTAT00000016216", "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035720": { "compartment": "compartment_7660", "id": "reaction_10035720", "reactome": "R-BTA-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035716", "species_10035710" ], "products": [ "species_10035718" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035712": { "compartment": "compartment_7660", "id": "reaction_10035712", "reactome": "R-BTA-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035708", "species_10035704" ], "products": [ "species_10035710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "ENSBTAT00000014945", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748" ] }, "reaction_10074759": { "compartment": "compartment_7660", "id": "reaction_10074759", "reactome": "R-BTA-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074755" ], "products": [ "species_10035716", "species_10074757" ], "modifiers": [], "additional_components": [ "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000017598", "ENSBTAT00000016216" ] }, "reaction_10074747": { "compartment": "compartment_7660", "id": "reaction_10074747", "reactome": "R-BTA-5683986", "name": "APBB1 and MAPK8 bind diphosphorylated H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074743", "species_10074733", "species_10039497" ], "products": [ "species_10074745" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069360", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000087439", "A0A3Q1LWJ8", "ENSBTAT00000087439", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1MU04", "ENSBTAT00000069360" ] }, "reaction_10074558": { "compartment": "compartment_7660", "id": "reaction_10074558", "reactome": "R-BTA-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074548" ], "products": [ "species_113582", "species_10074555" ], "modifiers": [ [ "species_10074548", "catalyst" ] ], "additional_components": [ "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10074736": { "compartment": "compartment_7660", "id": "reaction_10074736", "reactome": "R-BTA-5683964", "name": "ATM phosphorylates EYA1-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074724" ], "products": [ "species_113582", "species_10074727" ], "modifiers": [ [ "species_10074733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074020", "ENSBTAT00000074020", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074739": { "compartment": "compartment_7660", "id": "reaction_10074739", "reactome": "R-BTA-5683967", "name": "EYA1-4 dephosphorylates tyrosine Y142 of H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10074733" ], "products": [ "species_113550", "species_10074663" ], "modifiers": [ [ "species_10074727", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000074020" ] }, "reaction_10074677": { "compartment": "compartment_7660", "id": "reaction_10074677", "reactome": "R-BTA-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074674" ], "products": [ "species_113582", "species_10074667" ], "modifiers": [ [ "species_10074674", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074679": { "compartment": "compartment_7660", "id": "reaction_10074679", "reactome": "R-BTA-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069716", "species_10074542" ], "products": [ "species_10074544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002687", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687" ] }, "reaction_10074550": { "compartment": "compartment_7660", "id": "reaction_10074550", "reactome": "R-BTA-5682586", "name": "HERC2 and PIAS4 are recruited to DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069303", "species_10074546", "species_10069553" ], "products": [ "species_10074548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001000", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "ENSBTAT00000018496", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10076329": { "compartment": "compartment_7660", "id": "reaction_10076329", "reactome": "R-BTA-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074663", "species_10076288" ], "products": [ "species_10076290" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10076332": { "compartment": "compartment_7660", "id": "reaction_10076332", "reactome": "R-BTA-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076295", "species_29358" ], "products": [ "species_113582", "species_10074530" ], "modifiers": [ [ "species_10076295", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10076303": { "compartment": "compartment_7660", "id": "reaction_10076303", "reactome": "R-BTA-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076300" ], "products": [ "species_113582", "species_10074733" ], "modifiers": [ [ "species_10076300", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076334": { "compartment": "compartment_7660", "id": "reaction_10076334", "reactome": "R-BTA-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074530", "species_10074715" ], "products": [ "species_10076300" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074670": { "compartment": "compartment_7660", "id": "reaction_10074670", "reactome": "R-BTA-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10074667" ], "products": [ "species_77502", "species_10074542" ], "modifiers": [ [ "species_10074667", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074720": { "compartment": "compartment_7660", "id": "reaction_10074720", "reactome": "R-BTA-5683930", "name": "WICH phosphorylates H2AFX on Y142", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074711" ], "products": [ "species_113582", "species_10074715" ], "modifiers": [ [ "species_10074717", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B6X6", "ENSBTAT00000072070", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10076293": { "compartment": "compartment_7660", "id": "reaction_10076293", "reactome": "R-BTA-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076290" ], "products": [ "species_113582", "species_10074665" ], "modifiers": [ [ "species_10076290", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10075173": { "compartment": "compartment_7660", "id": "reaction_10075173", "reactome": "R-BTA-5686578", "name": "Activated ATM phosphorylates ABL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075167" ], "products": [ "species_113582", "species_10075170" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080797", "ENSBTAT00000080797", "ENSBTAT00000040104" ] }, "reaction_10049230": { "compartment": "compartment_70101", "id": "reaction_10049230", "reactome": "R-BTA-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429926" ], "products": [ "species_430042", "species_429925" ], "modifiers": [ [ "species_10049227", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003732" ] }, "reaction_10049232": { "compartment": "compartment_70101", "id": "reaction_10049232", "reactome": "R-BTA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049219", "species_429974" ], "products": [ "species_10049221" ], "modifiers": [], "additional_components": [ "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566", "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566" ] }, "reaction_10061043": { "compartment": "compartment_17957", "id": "reaction_10061043", "reactome": "R-BTA-1855200", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024002" ], "products": [ "species_113551", "species_2024016" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10060963": { "compartment": "compartment_17957", "id": "reaction_10060963", "reactome": "R-BTA-1855163", "name": "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024008" ], "products": [ "species_113551", "species_2024012" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10061122": { "compartment": "compartment_17957", "id": "reaction_10061122", "reactome": "R-BTA-1855225", "name": "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024018" ], "products": [ "species_113551", "species_2564836" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10036907": { "compartment": "compartment_70101", "id": "reaction_10036907", "reactome": "R-BTA-111285", "name": "Formation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035351" ], "products": [ "species_10036905" ], "modifiers": [ [ "species_113578", "catalyst" ], [ "species_29602", "catalyst" ], [ "species_76577", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035339": { "compartment": "compartment_70101", "id": "reaction_10035339", "reactome": "R-BTA-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_29372", "species_111370", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035354": { "compartment": "compartment_70101", "id": "reaction_10035354", "reactome": "R-BTA-73815", "name": "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_29356", "species_29472" ], "products": [ "species_111294", "species_111292", "species_29404" ], "modifiers": [ [ "species_10035351", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10036909": { "compartment": "compartment_70101", "id": "reaction_10036909", "reactome": "R-BTA-111289", "name": "Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036905" ], "products": [ "species_10035351" ], "modifiers": [ [ "species_73566", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035308": { "compartment": "compartment_70101", "id": "reaction_10035308", "reactome": "R-BTA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10035305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084984" ] }, "reaction_10091727": { "compartment": "compartment_70101", "id": "reaction_10091727", "reactome": "R-BTA-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678719", "species_10035314" ], "products": [ "species_10035317" ], "modifiers": [], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10035342": { "compartment": "compartment_70101", "id": "reaction_10035342", "reactome": "R-BTA-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_111354", "species_111355" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035345": { "compartment": "compartment_70101", "id": "reaction_10035345", "reactome": "R-BTA-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111292", "species_113592", "species_29424" ], "products": [ "species_29372", "species_111338", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035329": { "compartment": "compartment_70101", "id": "reaction_10035329", "reactome": "R-BTA-73805", "name": "CAIR + Aspartate + ATP => SAICAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29448", "species_111395" ], "products": [ "species_29372", "species_29370", "species_111399" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10036928": { "compartment": "compartment_70101", "id": "reaction_10036928", "reactome": "R-BTA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10036925", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "A7MBG0", "ENSBTAT00000047061", "species_29926" ] }, "reaction_10035332": { "compartment": "compartment_70101", "id": "reaction_10035332", "reactome": "R-BTA-73806", "name": "AIR + CO2 => CAIR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111370", "species_113528" ], "products": [ "species_111395" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10035319": { "compartment": "compartment_70101", "id": "reaction_10035319", "reactome": "R-BTA-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29602", "species_29360" ], "products": [ "species_70106", "species_111584", "species_73473" ], "modifiers": [ [ "species_10035314", "catalyst" ], [ "species_111584", "inhibitor" ], [ "species_10035317", "inhibitor" ] ], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10076312": { "compartment": "compartment_7660", "id": "reaction_10076312", "reactome": "R-BTA-5693575", "name": "DNA-PKcs autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076309" ], "products": [ "species_113582", "species_10075286" ], "modifiers": [ [ "species_10076309", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076347": { "compartment": "compartment_7660", "id": "reaction_10076347", "reactome": "R-BTA-5693615", "name": "Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076305", "species_10076345" ], "products": [ "species_10076309" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10075295": { "compartment": "compartment_7660", "id": "reaction_10075295", "reactome": "R-BTA-5687183", "name": "PRKDC phosphorylates DCLRE1C at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075288" ], "products": [ "species_113582", "species_10075292" ], "modifiers": [ [ "species_10075288", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076286": { "compartment": "compartment_7660", "id": "reaction_10076286", "reactome": "R-BTA-5693533", "name": "DCLRE1C (ARTEMIS) processes DNA DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075292" ], "products": [ "species_10076283" ], "modifiers": [ [ "species_10075292", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076327": { "compartment": "compartment_7660", "id": "reaction_10076327", "reactome": "R-BTA-5693578", "name": "TDP1 and TDP2 process unligatable DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076283" ], "products": [ "species_10076314" ], "modifiers": [ [ "species_10076324", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10036649": { "compartment": "compartment_70101", "id": "reaction_10036649", "reactome": "R-BTA-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10036646", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A3Q1LZ00", "ENSBTAT00000077740" ] }, "reaction_10034989": { "compartment": "compartment_70101", "id": "reaction_10034989", "reactome": "R-BTA-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10034986", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A452DII0", "ENSBTAT00000014316" ] }, "reaction_10035020": { "compartment": "compartment_70101", "id": "reaction_10035020", "reactome": "R-BTA-73632", "name": "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_83928" ], "products": [ "species_29370", "species_109366" ], "modifiers": [ [ "species_10035017", "catalyst" ] ], "additional_components": [ "A0A3Q1NEX0", "ENSBTAT00000073714" ] }, "reaction_10035007": { "compartment": "compartment_70101", "id": "reaction_10035007", "reactome": "R-BTA-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500829" ], "products": [ "species_500430", "species_31633" ], "modifiers": [ [ "species_10035004", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "CHEBI:16450", "CHEBI:16704", "species_29426", "A0A3Q1MGS0", "ENSBTAT00000074118" ] }, "reaction_10088624": { "compartment": "compartment_70101", "id": "reaction_10088624", "reactome": "R-BTA-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10088621", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "ENSBTAT00000071389" ] }, "reaction_10034980": { "compartment": "compartment_70101", "id": "reaction_10034980", "reactome": "R-BTA-73598", "name": "(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_113592" ], "products": [ "species_500828", "species_29370" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "species_727810", "species_109378", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035479": { "compartment": "compartment_70101", "id": "reaction_10035479", "reactome": "R-BTA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10036614": { "compartment": "compartment_5460", "id": "reaction_10036614", "reactome": "R-BTA-109759", "name": "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500822" ], "products": [ "species_113581", "species_500823" ], "modifiers": [ [ "species_10036611", "catalyst" ] ], "additional_components": [ "species_83928", "CHEBI:16450", "CHEBI:15698", "species_109366", "species_500742", "species_109378", "ENSBTAT00000064369" ] }, "reaction_10069313": { "compartment": "compartment_984", "id": "reaction_10069313", "reactome": "R-BTA-4084505", "name": "Laminins bind HSPG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693", "species_10069309" ], "products": [ "species_10069311" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022744", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "F1MER7", "ENSBTAT00000022744" ] }, "reaction_10044515": { "compartment": "compartment_984", "id": "reaction_10044515", "reactome": "R-BTA-216048", "name": "Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044511", "species_10044490" ], "products": [ "species_10044513" ], "modifiers": [], "additional_components": [ "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126" ] }, "reaction_10065555": { "compartment": "compartment_984", "id": "reaction_10065555", "reactome": "R-BTA-2426450", "name": "Laminins:Nidogens binds collagen type IV networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_10065551" ], "products": [ "species_10065553" ], "modifiers": [], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10047065": { "compartment": "compartment_17951", "id": "reaction_10047065", "reactome": "R-BTA-390438", "name": "FAR2 reduces PalmCoA to HXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200993" ], "products": [ "species_29366", "species_8848577", "species_76194" ], "modifiers": [ [ "species_10047062", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014725" ] }, "reaction_10083577": { "compartment": "compartment_12045", "id": "reaction_10083577", "reactome": "R-BTA-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_30209" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10083575": { "compartment": "compartment_12045", "id": "reaction_10083575", "reactome": "R-BTA-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_8848499", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10091611": { "compartment": "compartment_70101", "id": "reaction_10091611", "reactome": "R-BTA-9663492", "name": "BIL dissociates from GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091609" ], "products": [ "species_10091607", "species_189386" ], "modifiers": [], "additional_components": [ "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091613": { "compartment": "compartment_70101", "id": "reaction_10091613", "reactome": "R-BTA-9663511", "name": "BIL binds GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091607", "species_189386" ], "products": [ "species_10091609" ], "modifiers": [], "additional_components": [ "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091598": { "compartment": "compartment_70101", "id": "reaction_10091598", "reactome": "R-BTA-9661397", "name": "SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10091605": { "compartment": "compartment_70101", "id": "reaction_10091605", "reactome": "R-BTA-9661799", "name": "SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10091602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10069412": { "compartment": "compartment_876", "id": "reaction_10069412", "reactome": "R-BTA-4088281", "name": "Endorepellin binds KDR (VEGFR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041457", "species_10068872" ], "products": [ "species_10069410" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001038", "ENSBTAT00000022744", "F1MER7", "ENSBTAT00000022744", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10074474": { "compartment": "compartment_12045", "id": "reaction_10074474", "reactome": "R-BTA-5682084", "name": "ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_10074459" ], "products": [ "species_10074467", "species_76194" ], "modifiers": [ [ "species_10074471", "catalyst" ] ], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538", "ENSBTAT00000006197" ] }, "reaction_10074486": { "compartment": "compartment_12045", "id": "reaction_10074486", "reactome": "R-BTA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074467" ], "products": [ "species_10074478" ], "modifiers": [], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538" ] }, "reaction_10076091": { "compartment": "compartment_70101", "id": "reaction_10076091", "reactome": "R-BTA-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10039822" ], "products": [ "species_10076089" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "ENSBTAT00000068449", "F1MYD0", "ENSBTAT00000068449", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10059181": { "compartment": "compartment_70101", "id": "reaction_10059181", "reactome": "R-BTA-1562626", "name": "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_71067", "species_29368" ], "products": [ "species_5691103" ], "modifiers": [ [ "species_10059178", "catalyst" ] ], "additional_components": [ "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "O46415", "ENSBTAT00000009965" ] }, "reaction_10076083": { "compartment": "compartment_70101", "id": "reaction_10076083", "reactome": "R-BTA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076005", "species_10033408" ], "products": [ "species_10076074" ], "modifiers": [ [ "species_10076080", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077304", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000077304", "E1BJ64", "ENSBTAT00000028591", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10052866": { "compartment": "compartment_984", "id": "reaction_10052866", "reactome": "R-BTA-917805", "name": "CYBRD1:Heme reduces Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917828", "species_912516" ], "products": [ "species_435347" ], "modifiers": [ [ "species_10052863", "catalyst" ] ], "additional_components": [ "species_71185", "F1MLZ1", "ENSBTAT00000010387" ] }, "reaction_10052916": { "compartment": "compartment_984", "id": "reaction_10052916", "reactome": "R-BTA-917888", "name": "apoTF binds 2Fe3+ to form holoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_912516", "species_10051000" ], "products": [ "species_10052874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10087646": { "compartment": "compartment_70616", "id": "reaction_10087646", "reactome": "R-BTA-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2889072", "species_8949220" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10087643", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10061116": { "compartment": "compartment_70101", "id": "reaction_10061116", "reactome": "R-BTA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10060956": { "compartment": "compartment_70101", "id": "reaction_10060956", "reactome": "R-BTA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061040": { "compartment": "compartment_70101", "id": "reaction_10061040", "reactome": "R-BTA-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061011": { "compartment": "compartment_70101", "id": "reaction_10061011", "reactome": "R-BTA-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10061008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10060980": { "compartment": "compartment_70101", "id": "reaction_10060980", "reactome": "R-BTA-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10060983": { "compartment": "compartment_70101", "id": "reaction_10060983", "reactome": "R-BTA-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023943" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10060969", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797" ] }, "reaction_10061079": { "compartment": "compartment_70101", "id": "reaction_10061079", "reactome": "R-BTA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061034": { "compartment": "compartment_70101", "id": "reaction_10061034", "reactome": "R-BTA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063018": { "compartment": "compartment_70101", "id": "reaction_10063018", "reactome": "R-BTA-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023974" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061037": { "compartment": "compartment_70101", "id": "reaction_10061037", "reactome": "R-BTA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063020": { "compartment": "compartment_70101", "id": "reaction_10063020", "reactome": "R-BTA-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_29372", "species_2023974" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061024": { "compartment": "compartment_70101", "id": "reaction_10061024", "reactome": "R-BTA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061125": { "compartment": "compartment_70101", "id": "reaction_10061125", "reactome": "R-BTA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061113": { "compartment": "compartment_876", "id": "reaction_10061113", "reactome": "R-BTA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061110", "catalyst" ] ], "additional_components": [ "species_74016", "E1BJE0", "ENSBTAT00000034821", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MTE8", "ENSBTAT00000078103", "A0A3Q1M8P8", "ENSBTAT00000085120" ] }, "reaction_10061084": { "compartment": "compartment_70101", "id": "reaction_10061084", "reactome": "R-BTA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10061081", "catalyst" ] ], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10061006": { "compartment": "compartment_70101", "id": "reaction_10061006", "reactome": "R-BTA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061003", "catalyst" ] ], "additional_components": [ "species_74016", "Q1RML2", "ENSBTAT00000017574", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10060917": { "compartment": "compartment_70101", "id": "reaction_10060917", "reactome": "R-BTA-1855153", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114520" ], "products": [ "species_29370", "species_994170" ], "modifiers": [ [ "species_10060914", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LNH2", "ENSBTAT00000070709", "A0A3Q1MR28", "ENSBTAT00000044622", "F1MN32", "ENSBTAT00000025930", "A4FV33", "ENSBTAT00000002194" ] }, "reaction_10061076": { "compartment": "compartment_12045", "id": "reaction_10061076", "reactome": "R-BTA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10061073", "catalyst" ] ], "additional_components": [ "A0A3Q1LJY0", "ENSBTAT00000074483", "species_74016" ] }, "reaction_10036003": { "compartment": "compartment_7660", "id": "reaction_10036003", "reactome": "R-BTA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034244", "species_10034248" ], "products": [ "species_10034250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011684", "ENSBTAT00000061170", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10084424": { "compartment": "compartment_13977", "id": "reaction_10084424", "reactome": "R-BTA-8856630", "name": "CIDEA:CIDEC binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084420", "species_8866926" ], "products": [ "species_10084422" ], "modifiers": [], "additional_components": [ "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299" ] }, "reaction_10084480": { "compartment": "compartment_12045", "id": "reaction_10084480", "reactome": "R-BTA-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10084476" ], "products": [ "species_10084478" ], "modifiers": [], "additional_components": [ "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "species_549167" ] }, "reaction_10084694": { "compartment": "compartment_70101", "id": "reaction_10084694", "reactome": "R-BTA-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084690", "species_8866926" ], "products": [ "species_10084692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038453", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "Q29RS1", "ENSBTAT00000038453" ] }, "reaction_10083544": { "compartment": "compartment_70101", "id": "reaction_10083544", "reactome": "R-BTA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10083541", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021067" ] }, "reaction_10083547": { "compartment": "compartment_70101", "id": "reaction_10083547", "reactome": "R-BTA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10083541", "catalyst" ], [ "species_10083337", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000021067", "ENSBTAT00000015669" ] }, "reaction_10071388": { "compartment": "compartment_70101", "id": "reaction_10071388", "reactome": "R-BTA-5334794", "name": "FABPs bind LCFAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876730", "species_10071384" ], "products": [ "species_10071386" ], "modifiers": [], "additional_components": [ "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "species_1602366" ] }, "reaction_10035435": { "compartment": "compartment_70101", "id": "reaction_10035435", "reactome": "R-BTA-74213", "name": "Adenine + PRPP => AMP + PPi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10035432", "catalyst" ] ], "additional_components": [ "A0A452DIE3", "ENSBTAT00000000841" ] }, "reaction_10051215": { "compartment": "compartment_70101", "id": "reaction_10051215", "reactome": "R-BTA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10051212", "catalyst" ] ], "additional_components": [ "F1MCZ0", "ENSBTAT00000003519", "F6R1R5", "ENSBTAT00000020904" ] }, "reaction_10036001": { "compartment": "compartment_70101", "id": "reaction_10036001", "reactome": "R-BTA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10035998", "catalyst" ] ], "additional_components": [ "E1BA23", "ENSBTAT00000021018", "F1MLX6", "ENSBTAT00000015348", "A0A3Q1M723", "ENSBTAT00000080896" ] }, "reaction_10035426": { "compartment": "compartment_5460", "id": "reaction_10035426", "reactome": "R-BTA-74207", "name": "dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500224" ], "products": [ "species_113581", "species_500222" ], "modifiers": [ [ "species_10035423", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "CHEBI:28997", "species_109327", "species_109386", "species_2509805", "Q2KIN2", "ENSBTAT00000047239" ] }, "reaction_10036306": { "compartment": "compartment_70101", "id": "reaction_10036306", "reactome": "R-BTA-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_500088", "species_29370" ], "modifiers": [ [ "species_10036303", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "A0A3Q1MB39", "ENSBTAT00000071820", "species_29926" ] }, "reaction_10036308": { "compartment": "compartment_70101", "id": "reaction_10036308", "reactome": "R-BTA-109671", "name": "deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500201", "species_113592" ], "products": [ "species_29370", "species_500199" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "species_109386", "species_109327", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035444": { "compartment": "compartment_70101", "id": "reaction_10035444", "reactome": "R-BTA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10035441", "catalyst" ] ], "additional_components": [ "species_83956", "species_29850", "species_2509792", "species_113578", "Q3SZ18", "ENSBTAT00000019547", "species_29926" ] }, "reaction_10050378": { "compartment": "compartment_7660", "id": "reaction_10050378", "reactome": "R-BTA-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050287" ], "products": [ "species_113582", "species_10050298" ], "modifiers": [ [ "species_10050375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000805", "ENSBTAT00000000805", "ENSBTAT00000078659" ] }, "reaction_10050368": { "compartment": "compartment_7660", "id": "reaction_10050368", "reactome": "R-BTA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050287", "species_450613" ], "products": [ "species_10050289" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050400": { "compartment": "compartment_7660", "id": "reaction_10050400", "reactome": "R-BTA-450595", "name": "HuR:mRNA complex translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050304" ], "products": [ "species_10050398", "species_10050382" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000000141" ] }, "reaction_10051219": { "compartment": "compartment_7660", "id": "reaction_10051219", "reactome": "R-BTA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050293", "species_450605" ], "products": [ "species_10050295" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050306": { "compartment": "compartment_7660", "id": "reaction_10050306", "reactome": "R-BTA-450387", "name": "HuR binds the CRM1 nuclear export machinery", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050261", "species_10050273", "species_10050302", "species_10050269", "species_10050283", "species_10050265" ], "products": [ "species_10050304" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000141", "ENSBTAT00000029190", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000016410", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10051221": { "compartment": "compartment_7660", "id": "reaction_10051221", "reactome": "R-BTA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050298", "species_517622" ], "products": [ "species_10050300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10051066": { "compartment": "compartment_70101", "id": "reaction_10051066", "reactome": "R-BTA-482788", "name": "p-S54,92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050363" ], "products": [ "species_10051064" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050366": { "compartment": "compartment_70101", "id": "reaction_10050366", "reactome": "R-BTA-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050357", "species_113592" ], "products": [ "species_29370", "species_10050363" ], "modifiers": [ [ "species_10040551", "catalyst" ] ], "additional_components": [ "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "ENSBTAT00000084476" ] }, "reaction_10050318": { "compartment": "compartment_70101", "id": "reaction_10050318", "reactome": "R-BTA-450406", "name": "p-S92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050314" ], "products": [ "species_10050316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050373": { "compartment": "compartment_70101", "id": "reaction_10050373", "reactome": "R-BTA-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450523", "species_10050355" ], "products": [ "species_10050357" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778" ] }, "reaction_10050408": { "compartment": "compartment_70101", "id": "reaction_10050408", "reactome": "R-BTA-450620", "name": "p-S193-KSRP binds 14-3-3zeta in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050402", "species_10050371" ], "products": [ "species_10050406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "ENSBTAT00000070369", "P63103", "ENSBTAT00000000289", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10050380": { "compartment": "compartment_70101", "id": "reaction_10050380", "reactome": "R-BTA-450592", "name": "KSRP binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050322", "species_450386" ], "products": [ "species_10050324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070369", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10049346": { "compartment": "compartment_876", "id": "reaction_10049346", "reactome": "R-BTA-434381", "name": "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400452" ], "products": [ "species_3632881" ], "modifiers": [ [ "species_10049343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080828" ] }, "reaction_10049351": { "compartment": "compartment_17906", "id": "reaction_10049351", "reactome": "R-BTA-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_1132084", "species_200993", "species_76577" ], "modifiers": [ [ "species_10049348", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022939" ] }, "reaction_10044634": { "compartment": "compartment_70101", "id": "reaction_10044634", "reactome": "R-BTA-265682", "name": "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044615", "species_113592" ], "products": [ "species_6790050", "species_10044619" ], "modifiers": [ [ "species_10044615", "catalyst" ], [ "species_70113", "catalyst" ], [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ], [ "species_158417", "inhibitor" ] ], "additional_components": [ "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_29926", "species_29370", "A2VDS4", "ENSBTAT00000021523", "species_113592", "E1BKR6", "ENSBTAT00000046676", "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10047765": { "compartment": "compartment_876", "id": "reaction_10047765", "reactome": "R-BTA-400071", "name": "Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10034971": { "compartment": "compartment_70101", "id": "reaction_10034971", "reactome": "R-BTA-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109378" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10034968", "catalyst" ] ], "additional_components": [ "A6QQC3", "ENSBTAT00000083533" ] }, "reaction_10035038": { "compartment": "compartment_70101", "id": "reaction_10035038", "reactome": "R-BTA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10035035", "catalyst" ] ], "additional_components": [ "A0JNE9", "ENSBTAT00000068403" ] }, "reaction_10035698": { "compartment": "compartment_70101", "id": "reaction_10035698", "reactome": "R-BTA-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500006" ], "products": [ "species_500009", "species_113592" ], "modifiers": [ [ "species_10034909", "catalyst" ] ], "additional_components": [ "species_205687", "CHEBI:28846", "species_110094", "species_727810", "species_109378", "species_109402", "ENSBTAT00000026582" ] }, "reaction_10035029": { "compartment": "compartment_70101", "id": "reaction_10035029", "reactome": "R-BTA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10035026", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "A0A3Q1N7A8", "ENSBTAT00000069715" ] }, "reaction_10036692": { "compartment": "compartment_70101", "id": "reaction_10036692", "reactome": "R-BTA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10036689", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023406" ] }, "reaction_10034998": { "compartment": "compartment_70101", "id": "reaction_10034998", "reactome": "R-BTA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10034995", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NID0", "ENSBTAT00000077973" ] }, "reaction_10036683": { "compartment": "compartment_70101", "id": "reaction_10036683", "reactome": "R-BTA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_727810", "species_109378", "species_109386", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10036938": { "compartment": "compartment_70101", "id": "reaction_10036938", "reactome": "R-BTA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036935", "species_29450" ], "products": [ "species_10036932", "species_111745" ], "modifiers": [ [ "species_10036935", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001575", "ENSBTAT00000001575", "ENSBTAT00000001575" ] }, "reaction_10036685": { "compartment": "compartment_70101", "id": "reaction_10036685", "reactome": "R-BTA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_76577", "species_727810", "species_109378", "species_109386", "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10051075": { "compartment": "compartment_5460", "id": "reaction_10051075", "reactome": "R-BTA-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_482803" ], "products": [ "species_113581", "species_482807" ], "modifiers": [ [ "species_10051072", "catalyst" ] ], "additional_components": [ "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "species_110614", "species_29438", "species_500739", "species_29892", "species_29494", "species_29604", "species_30185", "species_30187", "F1N6T4", "ENSBTAT00000047964" ] }, "reaction_10077890": { "compartment": "compartment_5460", "id": "reaction_10077890", "reactome": "R-BTA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10077887", "catalyst" ] ], "additional_components": [ "species_727810", "species_109386", "species_76577", "species_109378", "species_29370", "CHEBI:16174", "CHEBI:28846", "species_110094", "ENSBTAT00000043366" ] }, "reaction_10082948": { "compartment": "compartment_5460", "id": "reaction_10082948", "reactome": "R-BTA-6810472", "name": "NUDT13 hydrolyses AP6A to AP4 and ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810468", "species_113521" ], "products": [ "species_113581", "species_6810471" ], "modifiers": [ [ "species_10082945", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000407" ] }, "reaction_10035047": { "compartment": "compartment_7660", "id": "reaction_10035047", "reactome": "R-BTA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10035044", "catalyst" ] ], "additional_components": [ "A0A3Q1MT44", "ENSBTAT00000070515" ] }, "reaction_10035481": { "compartment": "compartment_70101", "id": "reaction_10035481", "reactome": "R-BTA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10034953": { "compartment": "compartment_70101", "id": "reaction_10034953", "reactome": "R-BTA-73589", "name": "5,6-dihydrouracil + H2O => beta-ureidopropionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73584" ], "products": [ "species_73588" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10036267": { "compartment": "compartment_5460", "id": "reaction_10036267", "reactome": "R-BTA-109514", "name": "TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500420", "species_113521" ], "products": [ "species_113548", "species_500421" ], "modifiers": [ [ "species_10036264", "catalyst" ] ], "additional_components": [ "species_109366", "species_500742", "CHEBI:28895", "species_109402", "CHEBI:28070", "species_83928", "CHEBI:16450", "CHEBI:16704", "species_29926", "E1B8C1", "ENSBTAT00000043576" ] }, "reaction_10036209": { "compartment": "compartment_984", "id": "reaction_10036209", "reactome": "R-BTA-109291", "name": "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500316" ], "products": [ "species_109277", "species_500318" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_109402", "species_727810", "species_109366", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035009": { "compartment": "compartment_70101", "id": "reaction_10035009", "reactome": "R-BTA-73618", "name": "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73541" ], "products": [ "species_73617" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10035011": { "compartment": "compartment_70101", "id": "reaction_10035011", "reactome": "R-BTA-73620", "name": "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73617" ], "products": [ "species_113528", "species_73619", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036258": { "compartment": "compartment_70101", "id": "reaction_10036258", "reactome": "R-BTA-109480", "name": "TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500414" ], "products": [ "species_29372", "species_500415" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "CHEBI:28070", "CHEBI:28895", "species_109366", "species_500742", "CHEBI:46322", "species_109402", "CHEBI:16450", "CHEBI:16704", "species_83928", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10034962": { "compartment": "compartment_70101", "id": "reaction_10034962", "reactome": "R-BTA-73591", "name": "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73588" ], "products": [ "species_113528", "species_73590", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036229": { "compartment": "compartment_70101", "id": "reaction_10036229", "reactome": "R-BTA-109380", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10036247": { "compartment": "compartment_70101", "id": "reaction_10036247", "reactome": "R-BTA-109449", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036244", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "Q32L46", "ENSBTAT00000033700" ] }, "reaction_10065163": { "compartment": "compartment_876", "id": "reaction_10065163", "reactome": "R-BTA-2230938", "name": "Hemoglobin:Haptoglobin:CD163 is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065129" ], "products": [ "species_10065161" ], "modifiers": [], "additional_components": [ "P85521", "ENSBTAT00000026215", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_113533", "P85521", "ENSBTAT00000026215", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533" ] }, "reaction_10064765": { "compartment": "compartment_984", "id": "reaction_10064765", "reactome": "R-BTA-2168897", "name": "LRP1 (CD91) binds Hemopexin:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064755", "species_10064761" ], "products": [ "species_10064763" ], "modifiers": [], "additional_components": [ "A0A452DI25", "ENSBTAT00000004635", "species_71185", "ENSBTAT00000017556", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10064753": { "compartment": "compartment_984", "id": "reaction_10064753", "reactome": "R-BTA-2168884", "name": "Ferriheme is transferred from Methemoglobin to Hemopexin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_10064747" ], "products": [ "species_10064751", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_917955", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10064757": { "compartment": "compartment_984", "id": "reaction_10064757", "reactome": "R-BTA-2168886", "name": "Hemopexin binds Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10064747" ], "products": [ "species_10064755" ], "modifiers": [], "additional_components": [ "species_71185", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10065173": { "compartment": "compartment_24337", "id": "reaction_10065173", "reactome": "R-BTA-2230983", "name": "LRP1:Hemopexin:heme is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064763" ], "products": [ "species_10065171" ], "modifiers": [], "additional_components": [ "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "species_917955" ] } }, "motif_reaction_dictionary": { "reaction_10087663": { "compartment": "compartment_70101", "id": "reaction_10087663", "reactome": "R-BTA-8950181", "name": "Y693-STAT4 dimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087657" ], "products": [ "species_10087661" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087795": { "compartment": "compartment_70101", "id": "reaction_10087795", "reactome": "R-BTA-8950778", "name": "p-Y693-STAT4 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087655" ], "products": [ "species_10087657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10087650": { "compartment": "compartment_70101", "id": "reaction_10087650", "reactome": "R-BTA-8950179", "name": "IL12B translocates from the cytosol to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087648" ], "products": [ "species_10049902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077926", "ENSBTAT00000077926" ] }, "reaction_10087732": { "compartment": "compartment_17957", "id": "reaction_10087732", "reactome": "R-BTA-8950410", "name": "IL12B:IL12B translocates from ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087728" ], "products": [ "species_10087730" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10088519": { "compartment": "compartment_70101", "id": "reaction_10088519", "reactome": "R-BTA-8952807", "name": "p-Y693-STAT4 dissociates after IL12:IL12R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088517" ], "products": [ "species_10087655" ], "modifiers": [], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1N0R2", "ENSBTAT00000030584", "ENSBTAT00000030584" ] }, "reaction_10045423": { "compartment": "compartment_984", "id": "reaction_10045423", "reactome": "R-BTA-374919", "name": "Noradrenaline clearance from the synaptic cleft", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10046151": { "compartment": "compartment_70101", "id": "reaction_10046151", "reactome": "R-BTA-379382", "name": "MAOA:FAD deaminates DA to DOPAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_159362" ], "products": [ "species_9677997", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10046153": { "compartment": "compartment_70101", "id": "reaction_10046153", "reactome": "R-BTA-379395", "name": "MAOA:FAD deaminates 3MT to HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954997", "species_29356", "species_29368" ], "products": [ "species_9677992", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10088657": { "compartment": "compartment_70101", "id": "reaction_10088657", "reactome": "R-BTA-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_159362" ], "products": [ "species_8954997", "species_71285" ], "modifiers": [ [ "species_10088654", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003905" ] }, "reaction_10046552": { "compartment": "compartment_5460", "id": "reaction_10046552", "reactome": "R-BTA-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_380598" ], "products": [ "species_113529", "species_380593", "species_29362" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10038000": { "compartment": "compartment_70101", "id": "reaction_10038000", "reactome": "R-BTA-141186", "name": "MAOA:FAD oxidatively deaminates of 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_209914", "species_29368" ], "products": [ "species_500604", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10078658": { "compartment": "compartment_70101", "id": "reaction_10078658", "reactome": "R-BTA-6798044", "name": "BTG2 binds CCR4-NOT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078654", "species_10078604" ], "products": [ "species_10078656" ], "modifiers": [], "additional_components": [ "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100", "ENSBTAT00000020860", "F1MNK6", "ENSBTAT00000020860", "A0A3Q1N4H7", "ENSBTAT00000087280", "A0A3Q1M5L7", "ENSBTAT00000071934", "E1BJH0", "ENSBTAT00000016027", "Q3ZC01", "ENSBTAT00000024009", "A7MB47", "ENSBTAT00000004955", "E1BCS1", "ENSBTAT00000019836", "A6QR51", "ENSBTAT00000023088", "A0A3Q1ME75", "ENSBTAT00000075104", "E1BHL0", "ENSBTAT00000010879", "A0A3Q1N546", "ENSBTAT00000071100" ] }, "reaction_10081380": { "compartment": "compartment_70101", "id": "reaction_10081380", "reactome": "R-BTA-6801675", "name": "PLK2 phosphorylates NPM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10081359" ], "products": [ "species_29370", "species_10081373" ], "modifiers": [ [ "species_10081377", "catalyst" ] ], "additional_components": [ "A0A3Q1LXL7", "ENSBTAT00000054559", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "ENSBTAT00000022307" ] }, "reaction_10081499": { "compartment": "compartment_70101", "id": "reaction_10081499", "reactome": "R-BTA-6803890", "name": "SFN dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037648" ], "products": [ "species_10037650" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012154", "Q0VC36", "ENSBTAT00000012154" ] }, "reaction_10078349": { "compartment": "compartment_7660", "id": "reaction_10078349", "reactome": "R-BTA-6791235", "name": "GADD45A binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077951", "species_10078345" ], "products": [ "species_10078347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033450", "ENSBTAT00000044590", "Q2TA06", "ENSBTAT00000044590", "Q3ZBN6", "ENSBTAT00000033450" ] }, "reaction_10077955": { "compartment": "compartment_7660", "id": "reaction_10077955", "reactome": "R-BTA-6791109", "name": "GADD45A binds PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039892", "species_10077951" ], "products": [ "species_10077953" ], "modifiers": [], "additional_components": [ "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000033450", "Q3ZBN6", "ENSBTAT00000033450", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10088542": { "compartment": "compartment_7660", "id": "reaction_10088542", "reactome": "R-BTA-8953013", "name": "E2F7 binds E2F8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530", "species_10088538" ], "products": [ "species_10088540" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10088546": { "compartment": "compartment_7660", "id": "reaction_10088546", "reactome": "R-BTA-8953037", "name": "E2F8 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088538" ], "products": [ "species_10088544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086675", "A0A3Q1M173", "ENSBTAT00000086675" ] }, "reaction_10088534": { "compartment": "compartment_7660", "id": "reaction_10088534", "reactome": "R-BTA-8952996", "name": "E2F7 forms homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088530" ], "products": [ "species_10088532" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022518", "A0A452DIR4", "ENSBTAT00000022518" ] }, "reaction_10041386": { "compartment": "compartment_70101", "id": "reaction_10041386", "reactome": "R-BTA-193964", "name": "CYP21A2 21-hydroxylates PROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_194037", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041393": { "compartment": "compartment_5460", "id": "reaction_10041393", "reactome": "R-BTA-193965", "name": "CYP11B2 oxidises 18HCORST to ALDO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194012", "species_113533", "species_113529", "species_113600" ], "products": [ "species_193982", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041269": { "compartment": "compartment_70101", "id": "reaction_10041269", "reactome": "R-BTA-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041267", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10041397": { "compartment": "compartment_5460", "id": "reaction_10041397", "reactome": "R-BTA-193995", "name": "CYP11B2 18-hydroxylates CORST to 18HCORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_194005", "species_113600" ], "products": [ "species_194012", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10041719": { "compartment": "compartment_70101", "id": "reaction_10041719", "reactome": "R-BTA-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_196344", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041415": { "compartment": "compartment_5460", "id": "reaction_10041415", "reactome": "R-BTA-194017", "name": "CYP11B2 oxidises 11DCORST to CORST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193988", "species_113600" ], "products": [ "species_113563", "species_194005", "species_113521" ], "modifiers": [ [ "species_10041390", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055451" ] }, "reaction_10076281": { "compartment": "compartment_70101", "id": "reaction_10076281", "reactome": "R-BTA-5693390", "name": "HSD17B11 dehydrogenates EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10076278", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008272" ] }, "reaction_10077113": { "compartment": "compartment_5460", "id": "reaction_10077113", "reactome": "R-BTA-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_5696835" ], "products": [ "species_113529", "species_5696848", "species_113600" ], "modifiers": [ [ "species_10077110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002073" ] }, "reaction_10041277": { "compartment": "compartment_70101", "id": "reaction_10041277", "reactome": "R-BTA-193060", "name": "CYP19A1 hydroxylates ANDST to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193079", "species_29364" ], "products": [ "species_29356", "species_193066", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10051676": { "compartment": "compartment_70101", "id": "reaction_10051676", "reactome": "R-BTA-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193066", "species_29364" ], "products": [ "species_193132", "species_29366" ], "modifiers": [ [ "species_10051673", "catalyst" ] ], "additional_components": [ "Q1JQD0", "ENSBTAT00000064720" ] }, "reaction_10041299": { "compartment": "compartment_70101", "id": "reaction_10041299", "reactome": "R-BTA-193143", "name": "CYP19A1 hydroxylates TEST to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_193057" ], "products": [ "species_193132", "species_29356", "species_29366", "species_29460" ], "modifiers": [ [ "species_10041274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019823" ] }, "reaction_10084679": { "compartment": "compartment_70101", "id": "reaction_10084679", "reactome": "R-BTA-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_29366" ], "products": [ "species_70106", "species_193066", "species_29364" ], "modifiers": [ [ "species_10084676", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004193" ] }, "reaction_10041692": { "compartment": "compartment_70616", "id": "reaction_10041692", "reactome": "R-BTA-196086", "name": "Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041690" ], "products": [ "species_193156", "species_10041688" ], "modifiers": [], "additional_components": [ "Q28918", "ENSBTAT00000047426", "species_193840", "ENSBTAT00000047426" ] }, "reaction_10041716": { "compartment": "compartment_17906", "id": "reaction_10041716", "reactome": "R-BTA-196126", "name": "CHOL translocates from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041714", "species_10041688" ], "products": [ "species_10041712", "species_10041690" ], "modifiers": [], "additional_components": [ "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "species_193840", "ENSBTAT00000047426", "E1BKK4", "ENSBTAT00000015578", "Q0VCL2", "ENSBTAT00000057451", "Q28918", "ENSBTAT00000047426", "species_193840" ] }, "reaction_10041684": { "compartment": "compartment_70101", "id": "reaction_10041684", "reactome": "R-BTA-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196095", "species_70106", "species_29364" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10041290": { "compartment": "compartment_70101", "id": "reaction_10041290", "reactome": "R-BTA-193070", "name": "CYP17A1 cleaves 17aHPREG to DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193124", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_176626" ], "modifiers": [ [ "species_10041281", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189", "ENSBTAT00000010386" ] }, "reaction_10050650": { "compartment": "compartment_70101", "id": "reaction_10050650", "reactome": "R-BTA-469659", "name": "SRD5A1 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10050647", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020570", "ENSBTAT00000010386" ] }, "reaction_10041293": { "compartment": "compartment_70101", "id": "reaction_10041293", "reactome": "R-BTA-193072", "name": "CYP17A1 17-hydroxylates P4 to 17aHPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193055", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193092" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041295": { "compartment": "compartment_70101", "id": "reaction_10041295", "reactome": "R-BTA-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176626", "species_29360" ], "products": [ "species_70106", "species_193079", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114", "ENSBTAT00000010386" ] }, "reaction_10092062": { "compartment": "compartment_70101", "id": "reaction_10092062", "reactome": "R-BTA-9705713", "name": "SRD5A2 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10092059", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004043", "ENSBTAT00000010386" ] }, "reaction_10041297": { "compartment": "compartment_70101", "id": "reaction_10041297", "reactome": "R-BTA-193099", "name": "CYP17A1 cleaves 17aHPROG to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_29510", "species_29366", "species_193079" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10092065": { "compartment": "compartment_70101", "id": "reaction_10092065", "reactome": "R-BTA-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_469662", "species_29366" ], "modifiers": [ [ "species_10069495", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855", "ENSBTAT00000010386" ] }, "reaction_10041284": { "compartment": "compartment_70101", "id": "reaction_10041284", "reactome": "R-BTA-193068", "name": "CYP17A1 17-hydroxylates PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_193124" ], "modifiers": [ [ "species_10041281", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074189" ] }, "reaction_10041721": { "compartment": "compartment_70101", "id": "reaction_10041721", "reactome": "R-BTA-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_196366", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10057880": { "compartment": "compartment_984", "id": "reaction_10057880", "reactome": "R-BTA-1449687", "name": "Corticosteroids bind to CBG in blood", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1449707", "species_10057876" ], "products": [ "species_10057878" ], "modifiers": [], "additional_components": [ "species_193982", "species_193055", "species_194011", "species_193988", "ENSBTAT00000023402", "E1BF81", "ENSBTAT00000023402", "species_193982", "species_193055", "species_194011", "species_193988" ] }, "reaction_10041424": { "compartment": "compartment_17957", "id": "reaction_10041424", "reactome": "R-BTA-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193977", "species_29366" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10041421", "catalyst" ] ], "additional_components": [ "F6PTG3", "ENSBTAT00000020078" ] }, "reaction_10041379": { "compartment": "compartment_70101", "id": "reaction_10041379", "reactome": "R-BTA-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10041253", "catalyst" ] ], "additional_components": [ "P14893", "ENSBTAT00000087114" ] }, "reaction_10041395": { "compartment": "compartment_70101", "id": "reaction_10041395", "reactome": "R-BTA-193981", "name": "CYP21A2 oxidises 17HPROG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_193092", "species_29364" ], "products": [ "species_29356", "species_193966", "species_29366" ], "modifiers": [ [ "species_10041383", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007353" ] }, "reaction_10041412": { "compartment": "compartment_5460", "id": "reaction_10041412", "reactome": "R-BTA-193997", "name": "CYP11B1 oxidises 11DCORT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193998", "species_113529", "species_113600" ], "products": [ "species_113563", "species_194011", "species_113521" ], "modifiers": [ [ "species_10041409", "catalyst" ], [ "species_10041288", "catalyst" ] ], "additional_components": [ "F1MG97", "ENSBTAT00000055451", "F1MU47", "ENSBTAT00000006034", "F1MWH3", "ENSBTAT00000055451", "ENSBTAT00000010386" ] }, "reaction_10034240": { "compartment": "compartment_70101", "id": "reaction_10034240", "reactome": "R-BTA-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29398", "species_73473" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10089721": { "compartment": "compartment_5460", "id": "reaction_10089721", "reactome": "R-BTA-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089717", "species_9010792" ], "products": [ "species_10089719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011523", "F6Q200", "ENSBTAT00000011523" ] }, "reaction_10089728": { "compartment": "compartment_5460", "id": "reaction_10089728", "reactome": "R-BTA-9011595", "name": "GSTZ1 dimer dehalogenates DCA to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_113521" ], "products": [ "species_904849", "species_3301973" ], "modifiers": [ [ "species_10089725", "catalyst" ], [ "species_1655887", "catalyst" ], [ "species_9010792", "inhibitor" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10076468": { "compartment": "compartment_70101", "id": "reaction_10076468", "reactome": "R-BTA-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694074", "species_29450" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10076465", "catalyst" ] ], "additional_components": [ "species_29426", "A4FUZ1", "ENSBTAT00000016884" ] }, "reaction_10033671": { "compartment": "compartment_70101", "id": "reaction_10033671", "reactome": "R-BTA-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_29398", "species_73473" ], "modifiers": [ [ "species_10033668", "catalyst" ] ], "additional_components": [ "P19858", "ENSBTAT00000056276", "A0A3Q1M4R3", "ENSBTAT00000045699", "E1BNS9", "ENSBTAT00000003234" ] }, "reaction_10051980": { "compartment": "compartment_70616", "id": "reaction_10051980", "reactome": "R-BTA-880050", "name": "(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_880013" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051977", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020226" ] }, "reaction_10051973": { "compartment": "compartment_5460", "id": "reaction_10051973", "reactome": "R-BTA-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10051970", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_880067", "catalyst" ], [ "species_113527", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081426" ] }, "reaction_10033868": { "compartment": "compartment_5460", "id": "reaction_10033868", "reactome": "R-BTA-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113587", "species_113521" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10033865", "catalyst" ] ], "additional_components": [ "Q29RK1", "ENSBTAT00000005730" ] }, "reaction_10050446": { "compartment": "compartment_5460", "id": "reaction_10050446", "reactome": "R-BTA-450984", "name": "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_29938" ], "products": [ "species_113594", "species_113529", "species_113600", "species_29376" ], "modifiers": [ [ "species_10050443", "catalyst" ] ], "additional_components": [ "Q04467", "ENSBTAT00000018741", "species_113527" ] }, "reaction_10089808": { "compartment": "compartment_5460", "id": "reaction_10089808", "reactome": "R-BTA-9012349", "name": "ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_113544" ], "products": [ "species_113529", "species_113557", "species_113600", "species_29376" ], "modifiers": [ [ "species_10089805", "catalyst" ] ], "additional_components": [ "species_29926", "Q0VCX7", "ENSBTAT00000000306" ] }, "reaction_10089795": { "compartment": "compartment_5460", "id": "reaction_10089795", "reactome": "R-BTA-9012268", "name": "ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544", "species_113526" ], "products": [ "species_113529", "species_113557", "species_29362", "species_29376" ], "modifiers": [ [ "species_10089792", "catalyst" ], [ "species_113588", "catalyst" ], [ "species_113593", "inhibitor" ] ], "additional_components": [ "A0A3Q1MWG7", "ENSBTAT00000074198", "species_29926" ] }, "reaction_10050437": { "compartment": "compartment_5462", "id": "reaction_10050437", "reactome": "R-BTA-450971", "name": "NADPH + NAD+ + H+ [cytosol] => NADP+ + NADH + H+ [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113526", "species_113600" ], "products": [ "species_113563", "species_113529", "species_29362" ], "modifiers": [ [ "species_10050434", "catalyst" ] ], "additional_components": [ "P11024", "ENSBTAT00000080867" ] }, "reaction_10089782": { "compartment": "compartment_5460", "id": "reaction_10089782", "reactome": "R-BTA-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_113557", "species_29376" ], "modifiers": [ [ "species_10089779", "catalyst" ] ], "additional_components": [ "Q2HJ98", "ENSBTAT00000046873", "species_29926" ] }, "reaction_10073835": { "compartment": "compartment_17938", "id": "reaction_10073835", "reactome": "R-BTA-5672017", "name": "Rheb in the MTORC1 complex hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10074507": { "compartment": "compartment_5683628", "id": "reaction_10074507", "reactome": "R-BTA-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074495" ], "products": [ "species_10074505" ], "modifiers": [ [ "species_10052773", "catalyst" ] ], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "species_1602375", "species_1602375", "O41515", "ENSBTAT00000015449", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10074365": { "compartment": "compartment_70101", "id": "reaction_10074365", "reactome": "R-BTA-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10074362", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10074381": { "compartment": "compartment_70101", "id": "reaction_10074381", "reactome": "R-BTA-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074371", "species_10074377" ], "products": [ "species_10074379" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074415": { "compartment": "compartment_70101", "id": "reaction_10074415", "reactome": "R-BTA-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074399", "species_10074377" ], "products": [ "species_10074413" ], "modifiers": [], "additional_components": [ "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MB94", "ENSBTAT00000083637", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449" ] }, "reaction_10074142": { "compartment": "compartment_70101", "id": "reaction_10074142", "reactome": "R-BTA-5673768", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073828", "species_113592" ], "products": [ "species_29370", "species_10074140" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10074302": { "compartment": "compartment_70101", "id": "reaction_10074302", "reactome": "R-BTA-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693050", "species_10074298" ], "products": [ "species_10074300" ], "modifiers": [], "additional_components": [ "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "A0A3Q1MUP4", "ENSBTAT00000066992", "Q2KJ60", "ENSBTAT00000016002", "species_5693050" ] }, "reaction_10090398": { "compartment": "compartment_70101", "id": "reaction_10090398", "reactome": "R-BTA-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074379" ], "products": [ "species_10074653" ], "modifiers": [], "additional_components": [ "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301" ] }, "reaction_10074659": { "compartment": "compartment_70101", "id": "reaction_10074659", "reactome": "R-BTA-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074655", "species_10074653" ], "products": [ "species_10074657" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083652", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A0A3Q1LXA9", "ENSBTAT00000077815", "F1MZE2", "ENSBTAT00000023301", "A4FUE9", "ENSBTAT00000083652" ] }, "reaction_10070265": { "compartment": "compartment_17927", "id": "reaction_10070265", "reactome": "R-BTA-5205681", "name": "Pink1 is cleaved on healthy mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070263" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10070218": { "compartment": "compartment_70101", "id": "reaction_10070218", "reactome": "R-BTA-5205649", "name": "p62 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10070210" ], "products": [ "species_10070216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "D7GLD0", "ENSBTAT00000080672", "A0A3Q1LVE4", "ENSBTAT00000075019", "Q1LZE3", "ENSBTAT00000001994", "F1MPL1", "ENSBTAT00000013860", "O41515", "ENSBTAT00000015449" ] }, "reaction_10070259": { "compartment": "compartment_70101", "id": "reaction_10070259", "reactome": "R-BTA-5205661", "name": "Pink1 is recruited from the cytoplasm to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070224" ], "products": [ "species_10070226" ], "modifiers": [ [ "species_10070256", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455", "A6QPI6", "ENSBTAT00000013405", "Q2KI08", "ENSBTAT00000070920", "Q1LZB5", "ENSBTAT00000032251", "Q08E34", "ENSBTAT00000019001", "A8YXZ8", "ENSBTAT00000046547", "A6H7B1", "ENSBTAT00000000733", "Q56JY4", "ENSBTAT00000011817" ] }, "reaction_10070261": { "compartment": "compartment_17906", "id": "reaction_10070261", "reactome": "R-BTA-5205672", "name": "Uncleaved Pink1 accumulates in damaged mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070226" ], "products": [ "species_10070222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029455", "ENSBTAT00000029455" ] }, "reaction_10088891": { "compartment": "compartment_70101", "id": "reaction_10088891", "reactome": "R-BTA-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070214", "species_10087624" ], "products": [ "species_10088889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015449", "ENSBTAT00000002144", "F1N5S9", "ENSBTAT00000002144", "O41515", "ENSBTAT00000015449" ] }, "reaction_10087615": { "compartment": "compartment_70101", "id": "reaction_10087615", "reactome": "R-BTA-8948139", "name": "p-S13-FUNDC1 is dephosphorylated by PGAM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087608" ], "products": [ "species_10087605" ], "modifiers": [ [ "species_10087612", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000009887" ] }, "reaction_10087621": { "compartment": "compartment_70101", "id": "reaction_10087621", "reactome": "R-BTA-8948143", "name": "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087608" ], "products": [ "species_10087618", "species_29370" ], "modifiers": [ [ "species_10040957", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002144", "ENSBTAT00000002144", "ENSBTAT00000011767" ] }, "reaction_10073831": { "compartment": "compartment_17938", "id": "reaction_10073831", "reactome": "R-BTA-5672010", "name": "Active MTORC1 phosphorylates ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073822" ], "products": [ "species_10073828", "species_29370" ], "modifiers": [ [ "species_10073822", "catalyst" ] ], "additional_components": [ "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "E1BH45", "ENSBTAT00000076195", "Q2HJE0", "ENSBTAT00000000651", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10050514": { "compartment": "compartment_876", "id": "reaction_10050514", "reactome": "R-BTA-451283", "name": "kainate receptor binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10050510" ], "products": [ "species_10050512" ], "modifiers": [], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10050517": { "compartment": "compartment_70101", "id": "reaction_10050517", "reactome": "R-BTA-451311", "name": "Activation of Ca-permeable Kainate receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10050512", "catalyst" ] ], "additional_components": [ "A2VE57", "ENSBTAT00000070796", "species_352022", "Q2HJD2", "ENSBTAT00000015567", "A0A3Q1M9Y0", "ENSBTAT00000073656", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MBH0", "ENSBTAT00000084144", "P61602", "ENSBTAT00000068404", "A0A3Q1MFJ1", "ENSBTAT00000077778", "F1MCW8", "ENSBTAT00000022788", "species_210382" ] }, "reaction_10045419": { "compartment": "compartment_876", "id": "reaction_10045419", "reactome": "R-BTA-374896", "name": "Uptake of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_374935" ], "products": [ "species_209789" ], "modifiers": [ [ "species_10045416", "catalyst" ] ], "additional_components": [ "E1BHW6", "ENSBTAT00000012607" ] }, "reaction_10045421": { "compartment": "compartment_70101", "id": "reaction_10045421", "reactome": "R-BTA-374909", "name": "Metabolism of Noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209789", "species_29356", "species_29368" ], "products": [ "species_5279533", "species_29382", "species_29408" ], "modifiers": [ [ "species_10037997", "catalyst" ] ], "additional_components": [ "P21398", "ENSBTAT00000021570", "species_113596" ] }, "reaction_10039481": { "compartment": "compartment_70101", "id": "reaction_10039481", "reactome": "R-BTA-166869", "name": "TRAF6 binds MEKK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10039469" ], "products": [ "species_10039475" ], "modifiers": [ [ "species_10039479", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021630", "ENSBTAT00000018325", "E1B847", "ENSBTAT00000018325", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000020029" ] }, "reaction_10050256": { "compartment": "compartment_70101", "id": "reaction_10050256", "reactome": "R-BTA-450348", "name": "Activated human JNKs migrate to nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039518" ], "products": [ "species_10039505" ], "modifiers": [], "additional_components": [ "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10042826": { "compartment": "compartment_7660", "id": "reaction_10042826", "reactome": "R-BTA-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10042823", "catalyst" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "F1N1S8", "ENSBTAT00000007277" ] }, "reaction_10043488": { "compartment": "compartment_7660", "id": "reaction_10043488", "reactome": "R-BTA-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10041947" ], "products": [ "species_113550", "species_10042805" ], "modifiers": [ [ "species_10043479", "catalyst" ], [ "species_10043486", "inhibitor" ] ], "additional_components": [ "A5PKJ4", "ENSBTAT00000001347", "A5PKJ4", "ENSBTAT00000001347", "Q2T9T7", "ENSBTAT00000078874", "F1MM08", "ENSBTAT00000061049", "A6QLS1", "ENSBTAT00000029212", "Q2KJ36", "ENSBTAT00000006022", "Q2T9T7", "ENSBTAT00000078874", "Q2YDN8", "ENSBTAT00000007054" ] }, "reaction_10041950": { "compartment": "compartment_7660", "id": "reaction_10041950", "reactome": "R-BTA-198746", "name": "ERK1/2/5 activate RSK1/2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10041927" ], "products": [ "species_113582", "species_10041945" ], "modifiers": [ [ "species_10041947", "catalyst" ] ], "additional_components": [ "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174", "A5PKJ4", "ENSBTAT00000001347" ] }, "reaction_10050208": { "compartment": "compartment_7660", "id": "reaction_10050208", "reactome": "R-BTA-450292", "name": "Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039493", "species_10050204" ], "products": [ "species_10050206" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005660", "O77628", "ENSBTAT00000005660", "Q08DH1", "ENSBTAT00000005279" ] }, "reaction_10039508": { "compartment": "compartment_7660", "id": "reaction_10039508", "reactome": "R-BTA-168136", "name": "Activated JNKs phosphorylate c-JUN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10039489" ], "products": [ "species_113582", "species_10039493" ], "modifiers": [ [ "species_10039505", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005279", "ENSBTAT00000005279", "A0A3Q1LWJ8", "ENSBTAT00000087439", "A0A3Q1LJU7", "ENSBTAT00000082454" ] }, "reaction_10050218": { "compartment": "compartment_70101", "id": "reaction_10050218", "reactome": "R-BTA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050214" ], "products": [ "species_10050216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307" ] }, "reaction_10050254": { "compartment": "compartment_70101", "id": "reaction_10050254", "reactome": "R-BTA-450346", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10050251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LT51", "ENSBTAT00000068866", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176" ] }, "reaction_10050192": { "compartment": "compartment_7660", "id": "reaction_10050192", "reactome": "R-BTA-450222", "name": "Active p38 MAPK phosphorylates MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050185" ], "products": [ "species_113582", "species_10050189" ], "modifiers": [ [ "species_10050185", "catalyst" ] ], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050196": { "compartment": "compartment_70101", "id": "reaction_10050196", "reactome": "R-BTA-450257", "name": "Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050189" ], "products": [ "species_10050194" ], "modifiers": [], "additional_components": [ "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476" ] }, "reaction_10050231": { "compartment": "compartment_7660", "id": "reaction_10050231", "reactome": "R-BTA-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050228" ], "products": [ "species_113582", "species_10050185" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1M614", "ENSBTAT00000084476", "A0A3Q1M614", "ENSBTAT00000084476", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10069253": { "compartment": "compartment_876", "id": "reaction_10069253", "reactome": "R-BTA-3928651", "name": "NGEF exchanges GTP for GDP on RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069250", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "Q08DA6", "ENSBTAT00000011773" ] }, "reaction_10077455": { "compartment": "compartment_876", "id": "reaction_10077455", "reactome": "R-BTA-6784189", "name": "JAKs bind LIFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077414", "species_10049952" ], "products": [ "species_10077416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709" ] }, "reaction_10077422": { "compartment": "compartment_876", "id": "reaction_10077422", "reactome": "R-BTA-6783524", "name": "OSM,LIF,CTF1 receptor complex binds gp130", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049956", "species_10077418" ], "products": [ "species_10077420" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10077424": { "compartment": "compartment_876", "id": "reaction_10077424", "reactome": "R-BTA-6783552", "name": "OSM binds LIFR:JAKs,OSMR:JAKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077410", "species_10077416" ], "products": [ "species_10077418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021515", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BAT3", "ENSBTAT00000076709", "F1N366", "ENSBTAT00000021515" ] }, "reaction_10065517": { "compartment": "compartment_876", "id": "reaction_10065517", "reactome": "R-BTA-2424480", "name": "PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065514", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "F1MI53", "ENSBTAT00000074586", "A0A3Q1NAW3", "ENSBTAT00000070846", "A0A2Z2AM52", "ENSBTAT00000080723", "A3R3B5", "ENSBTAT00000077363", "A0A3Q1M7L0", "ENSBTAT00000075285", "A8E4Q0", "ENSBTAT00000031648", "A0A3Q1NM98", "ENSBTAT00000071353", "F1MHY4", "ENSBTAT00000006472", "A3R3B4", "ENSBTAT00000077363", "F1MPK9", "ENSBTAT00000055860", "A0A140T8B5", "ENSBTAT00000037859", "A0A3Q1N4Y9", "ENSBTAT00000068807", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0JNB0", "ENSBTAT00000015730", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065491": { "compartment": "compartment_876", "id": "reaction_10065491", "reactome": "R-BTA-2424477", "name": "SOS mediated nucleotide exchange of RAS (SHC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040851": { "compartment": "compartment_12045", "id": "reaction_10040851", "reactome": "R-BTA-190681", "name": "Connexin oligomerization in endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040846" ], "products": [ "species_10040848" ], "modifiers": [ [ "species_10040846", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027331", "O18968", "ENSBTAT00000027331", "ENSBTAT00000027331" ] }, "reaction_10049067": { "compartment": "compartment_114584", "id": "reaction_10049067", "reactome": "R-BTA-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_114565" ], "modifiers": [ [ "species_10049064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013298" ] }, "reaction_10051002": { "compartment": "compartment_984", "id": "reaction_10051002", "reactome": "R-BTA-482770", "name": "Release of platelet secretory granule components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050998" ], "products": [ "species_10051000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "ENSBTAT00000009564" ] }, "reaction_10050924": { "compartment": "compartment_876", "id": "reaction_10050924", "reactome": "R-BTA-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050904" ], "products": [ "species_10050922" ], "modifiers": [], "additional_components": [ "species_29438", "A7E3W2", "ENSBTAT00000001802", "species_29370", "species_29926", "Q29RS5", "ENSBTAT00000084323", "species_113592", "A0A3Q1M5Q6", "ENSBTAT00000076112", "A5PKI3", "ENSBTAT00000073296", "species_29372", "A0A452DIU4", "ENSBTAT00000024391", "species_74016", "A0A3Q1LTE4", "ENSBTAT00000080253", "Q27967", "ENSBTAT00000002631", "species_209914", "species_29420", "species_111294", "A6H754", "ENSBTAT00000022777", "species_74016", "species_29438", "Q27967", "ENSBTAT00000002631", "species_29370", "A6H754", "ENSBTAT00000022777", "species_111294", "A0A452DIU4", "ENSBTAT00000024391", "species_29926", "species_113592", "Q29RS5", "ENSBTAT00000084323", "A0A3Q1LTE4", "ENSBTAT00000080253", "species_209914", "A0A3Q1M5Q6", "ENSBTAT00000076112", "species_29372", "A5PKI3", "ENSBTAT00000073296", "species_29420", "A7E3W2", "ENSBTAT00000001802" ] }, "reaction_10050994": { "compartment": "compartment_876", "id": "reaction_10050994", "reactome": "R-BTA-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050980" ], "products": [ "species_10050992" ], "modifiers": [], "additional_components": [ "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "A0A3Q1LI93", "ENSBTAT00000075662", "P26201", "ENSBTAT00000080828", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A5PK28", "ENSBTAT00000067657", "A0A3Q1LEU1", "ENSBTAT00000081148", "A0A3Q1LN74", "ENSBTAT00000074339", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A1L6ZA12", "ENSBTAT00000087233", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LI93", "ENSBTAT00000075662", "A5PK28", "ENSBTAT00000067657", "P26201", "ENSBTAT00000080828", "A0A3Q1LN74", "ENSBTAT00000074339", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "A0A3Q1LEU1", "ENSBTAT00000081148" ] }, "reaction_10050948": { "compartment": "compartment_876", "id": "reaction_10050948", "reactome": "R-BTA-481010", "name": "Surface deployment of platelet dense granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050938" ], "products": [ "species_10050946" ], "modifiers": [], "additional_components": [ "Q8HZJ5", "ENSBTAT00000078091", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q9XSK2", "ENSBTAT00000015829", "Q8HZJ5", "ENSBTAT00000078091" ] }, "reaction_10050870": { "compartment": "compartment_876", "id": "reaction_10050870", "reactome": "R-BTA-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050802" ], "products": [ "species_10050868" ], "modifiers": [], "additional_components": [ "A0A452DIX0", "ENSBTAT00000026577", "P17697", "ENSBTAT00000007324", "A4IF69", "ENSBTAT00000004806", "F1MY12", "ENSBTAT00000016092", "A0A140T8C8", "ENSBTAT00000053071", "A0A0A0MP92", "ENSBTAT00000011576", "C4PU73", "ENSBTAT00000009718", "A0A0A0MPA0", "ENSBTAT00000038516", "G3N1U4", "ENSBTAT00000064475", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A0A0MP89", "ENSBTAT00000009261", "A0A452DJK6", "ENSBTAT00000064935", "E1BMJ0", "ENSBTAT00000021638", "Q9XS50", "ENSBTAT00000019613", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P28800", "ENSBTAT00000027793", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "A6QP91", "ENSBTAT00000015925", "E1BBY0", "ENSBTAT00000051964", "E1B726", "ENSBTAT00000001674", "A0A452DIJ9", "ENSBTAT00000019232", "G3X7J5", "ENSBTAT00000032623", "F1MD83", "ENSBTAT00000015874", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1M2H1", "ENSBTAT00000067311", "Q17QL4", "ENSBTAT00000007016", "A4IFA6", "ENSBTAT00000007913", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LPG8", "ENSBTAT00000083114", "G5E5W1", "ENSBTAT00000036726", "P12763", "ENSBTAT00000000673", "F1MX05", "ENSBTAT00000004949", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "Q2HJ33", "ENSBTAT00000009160", "P07455", "ENSBTAT00000014713", "A0A452DIJ9", "ENSBTAT00000019232", "P12763", "ENSBTAT00000000673", "Q5GN72", "ENSBTAT00000022991", "P07455", "ENSBTAT00000014713", "G8JKY5", "ENSBTAT00000024387", "A0A3Q1LMG1", "ENSBTAT00000083687", "E1BBY0", "ENSBTAT00000051964", "A4IFA6", "ENSBTAT00000007913", "E1BMJ0", "ENSBTAT00000021638", "P34955", "ENSBTAT00000072441", "Q3T0A3", "ENSBTAT00000063284", "P17697", "ENSBTAT00000007324", "F1MY12", "ENSBTAT00000016092", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1M2H1", "ENSBTAT00000067311", "A0A140T8C8", "ENSBTAT00000053071", "E1B726", "ENSBTAT00000001674", "A6QP91", "ENSBTAT00000015925", "A4IF69", "ENSBTAT00000004806", "F1MX05", "ENSBTAT00000004949", "G5E5W1", "ENSBTAT00000036726", "P28800", "ENSBTAT00000027793", "F1MD83", "ENSBTAT00000015874", "Q2HJ33", "ENSBTAT00000009160", "Q17QL4", "ENSBTAT00000007016", "A0A3Q1LPG8", "ENSBTAT00000083114", "G3X7J5", "ENSBTAT00000032623", "Q9XS50", "ENSBTAT00000019613", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A452DIX0", "ENSBTAT00000026577" ] }, "reaction_10051062": { "compartment": "compartment_70101", "id": "reaction_10051062", "reactome": "R-BTA-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051036" ], "products": [ "species_10051060" ], "modifiers": [], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "F1MHC2", "ENSBTAT00000012094", "P80513", "ENSBTAT00000045083", "P63258", "ENSBTAT00000008132", "F1MRZ8", "ENSBTAT00000012724", "A0A3Q1MLQ7", "ENSBTAT00000074863", "A7YY77", "ENSBTAT00000034535", "F1MNQ4", "ENSBTAT00000039344", "A0A3Q1LP13", "ENSBTAT00000075491", "E1B8Z0", "ENSBTAT00000079099", "Q5E9F5", "ENSBTAT00000080925", "A0A3Q1MLQ7", "ENSBTAT00000074863", "F1MHC2", "ENSBTAT00000012094", "A7YY77", "ENSBTAT00000034535", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1LP13", "ENSBTAT00000075491", "F1MRZ8", "ENSBTAT00000012724", "Q5E9F5", "ENSBTAT00000080925", "F1MNQ4", "ENSBTAT00000039344", "P80513", "ENSBTAT00000045083", "E1B8Z0", "ENSBTAT00000079099", "P63258", "ENSBTAT00000008132" ] }, "reaction_10090306": { "compartment": "compartment_876", "id": "reaction_10090306", "reactome": "R-BTA-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090272", "species_10090302" ], "products": [ "species_10090304" ], "modifiers": [], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29438", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "F1MWY5", "ENSBTAT00000023764", "A6H720", "ENSBTAT00000069542", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A5D7J5", "ENSBTAT00000024876", "species_29438" ] }, "reaction_10090311": { "compartment": "compartment_876", "id": "reaction_10090311", "reactome": "R-BTA-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090308" ], "products": [ "species_29420", "species_10090272" ], "modifiers": [ [ "species_10090308", "catalyst" ] ], "additional_components": [ "A5D7J5", "ENSBTAT00000024876", "species_29420", "A5D7J5", "ENSBTAT00000024876", "species_29438", "A5D7J5", "ENSBTAT00000024876", "species_29420" ] }, "reaction_10081497": { "compartment": "compartment_70101", "id": "reaction_10081497", "reactome": "R-BTA-6803789", "name": "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6803743" ], "products": [ "species_193473", "species_449701" ], "modifiers": [ [ "species_10081494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074115" ] }, "reaction_10050153": { "compartment": "compartment_70101", "id": "reaction_10050153", "reactome": "R-BTA-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512", "species_29472" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10050150", "catalyst" ] ], "additional_components": [ "F1MZY2", "ENSBTAT00000023441", "A0A452DHW0", "ENSBTAT00000002867" ] }, "reaction_10081490": { "compartment": "compartment_70101", "id": "reaction_10081490", "reactome": "R-BTA-6803771", "name": "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803785", "species_113592" ], "products": [ "species_6803738", "species_70106", "species_29370" ], "modifiers": [ [ "species_10081487", "catalyst" ] ], "additional_components": [ "CHEBI:27459", "species_1678743", "species_449703", "species_6803743", "A0A452DJF8", "ENSBTAT00000019528" ] }, "reaction_10049778": { "compartment": "compartment_70101", "id": "reaction_10049778", "reactome": "R-BTA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10049775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086526" ] }, "reaction_10069593": { "compartment": "compartment_70101", "id": "reaction_10069593", "reactome": "R-BTA-4608852", "name": "SMURF1/2 ubiquitinates PRICKLE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069585" ], "products": [ "species_10069588" ], "modifiers": [ [ "species_10069590", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072372", "ENSBTAT00000072372", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069595": { "compartment": "compartment_70101", "id": "reaction_10069595", "reactome": "R-BTA-4608854", "name": "SMURF1/2 are recruited to the DVL2:PARD6A complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069581", "species_10042973" ], "products": [ "species_10069590" ], "modifiers": [], "additional_components": [ "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000043725", "F6RHP0", "ENSBTAT00000032504", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MLS5", "ENSBTAT00000043725" ] }, "reaction_10069872": { "compartment": "compartment_876", "id": "reaction_10069872", "reactome": "R-BTA-5099886", "name": "WNT5A binding to FZD promotes PRICKLE1 degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069868", "species_10067196" ], "products": [ "species_10069870" ], "modifiers": [], "additional_components": [ "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10044480": { "compartment": "compartment_17960", "id": "reaction_10044480", "reactome": "R-BTA-215526", "name": "CYP4F3 20-hydroxylates LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215557", "species_113601" ], "products": [ "species_113519", "species_113564", "species_571314" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10071909": { "compartment": "compartment_12045", "id": "reaction_10071909", "reactome": "R-BTA-5602295", "name": "CYP4F22 20-hydroxylates TrXA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2142713", "species_29368", "species_29364" ], "products": [ "species_5602281", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066325" ] }, "reaction_10044151": { "compartment": "compartment_12045", "id": "reaction_10044151", "reactome": "R-BTA-211873", "name": "CYP4F2, 4F3 20-hydroxylate LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266056", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2161636" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10073037": { "compartment": "compartment_876", "id": "reaction_10073037", "reactome": "R-BTA-5654423", "name": "Activated FGFR4:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073033" ], "products": [ "species_10073035" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073041": { "compartment": "compartment_70101", "id": "reaction_10073041", "reactome": "R-BTA-5654425", "name": "Activated FGFR4 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065241" ], "products": [ "species_10073039" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073044": { "compartment": "compartment_70101", "id": "reaction_10073044", "reactome": "R-BTA-5654426", "name": "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073047": { "compartment": "compartment_70101", "id": "reaction_10073047", "reactome": "R-BTA-5654428", "name": "Activated FGFR4 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073039" ], "products": [ "species_29370", "species_10073033" ], "modifiers": [ [ "species_10073039", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10076847": { "compartment": "compartment_12045", "id": "reaction_10076847", "reactome": "R-BTA-5696119", "name": "AGMO cleaves alkylglycerol into fatty aldehyde and glycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_5696122", "species_29368" ], "products": [ "species_29356", "species_1497857", "species_76116", "species_5696116" ], "modifiers": [ [ "species_10076844", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069764" ] }, "reaction_10035838": { "compartment": "compartment_70101", "id": "reaction_10035838", "reactome": "R-BTA-75900", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_76103" ], "products": [ "species_549167", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10035795": { "compartment": "compartment_70101", "id": "reaction_10035795", "reactome": "R-BTA-75887", "name": "Conversion of Glycerol to Glycerol-3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76116" ], "products": [ "species_29370", "species_76114" ], "modifiers": [ [ "species_10035790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030932" ] }, "reaction_10035829": { "compartment": "compartment_70101", "id": "reaction_10035829", "reactome": "R-BTA-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76108", "species_29356" ], "products": [ "species_29372", "species_76103" ], "modifiers": [ [ "species_10035826", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LV95", "ENSBTAT00000067199" ] }, "reaction_10080887": { "compartment": "compartment_12045", "id": "reaction_10080887", "reactome": "R-BTA-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76103", "species_76194" ], "modifiers": [ [ "species_10080884", "catalyst" ] ], "additional_components": [ "Q70VZ7", "ENSBTAT00000011091", "F1MLQ3", "ENSBTAT00000010395", "G3MYF6", "ENSBTAT00000064201" ] }, "reaction_10090409": { "compartment": "compartment_7660", "id": "reaction_10090409", "reactome": "R-BTA-9021357", "name": "PRKCI phosphorylates ELF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10090404" ], "products": [ "species_113582", "species_10090404" ], "modifiers": [ [ "species_10090406", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011536", "ENSBTAT00000011536", "ENSBTAT00000061563" ] }, "reaction_10044826": { "compartment": "compartment_70101", "id": "reaction_10044826", "reactome": "R-BTA-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10044815" ], "products": [ "species_29420", "species_10044819" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "P84080", "ENSBTAT00000010159", "species_29420", "P84080", "ENSBTAT00000010159", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10045538": { "compartment": "compartment_70101", "id": "reaction_10045538", "reactome": "R-BTA-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10045525", "species_10045531" ], "products": [ "species_10045527", "species_10045525", "species_10045533" ], "modifiers": [ [ "species_10045535", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "ENSBTAT00000009899", "ENSBTAT00000085048", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10034921": { "compartment": "compartment_70101", "id": "reaction_10034921", "reactome": "R-BTA-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111628", "species_70106" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034924": { "compartment": "compartment_70101", "id": "reaction_10034924", "reactome": "R-BTA-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111647", "species_29448" ], "products": [ "species_111628", "species_29372" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10034927": { "compartment": "compartment_70101", "id": "reaction_10034927", "reactome": "R-BTA-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111627", "species_113592", "species_29472" ], "products": [ "species_111647", "species_29372", "species_29404", "species_29370" ], "modifiers": [ [ "species_10034918", "catalyst" ] ], "additional_components": [ "F1MVC0", "ENSBTAT00000023783" ] }, "reaction_10048761": { "compartment": "compartment_876", "id": "reaction_10048761", "reactome": "R-BTA-427656", "name": "SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048758", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084837" ] }, "reaction_10048754": { "compartment": "compartment_876", "id": "reaction_10048754", "reactome": "R-BTA-427645", "name": "SLC34A3 cotransports Pi, 2Na+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069253" ] }, "reaction_10065819": { "compartment": "compartment_984", "id": "reaction_10065819", "reactome": "R-BTA-2534248", "name": "DCN (decorin) degradation by MMP2, MMP3, MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065294" ], "products": [ "species_10065814", "species_10065812" ], "modifiers": [ [ "species_10065816", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004562", "ENSBTAT00000004562", "ENSBTAT00000004562", "F1MU56", "ENSBTAT00000006029", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059674": { "compartment": "compartment_984", "id": "reaction_10059674", "reactome": "R-BTA-1566962", "name": "Elastin degradation by elastin-degrading extracellular proteinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059657" ], "products": [ "species_10059665" ], "modifiers": [ [ "species_10059671", "catalyst" ] ], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTX6", "ENSBTAT00000013124", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10087324": { "compartment": "compartment_984", "id": "reaction_10087324", "reactome": "R-BTA-8940561", "name": "MMP7 cleaves OPTC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087311" ], "products": [ "species_10087319", "species_10087317", "species_10087315", "species_10087321" ], "modifiers": [ [ "species_10058184", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000018286", "ENSBTAT00000006029" ] }, "reaction_10064649": { "compartment": "compartment_876", "id": "reaction_10064649", "reactome": "R-BTA-2167942", "name": "Collagen type XIII ectodomain shedding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064303" ], "products": [ "species_10064625", "species_10064623" ], "modifiers": [], "additional_components": [ "F6RND5", "ENSBTAT00000039811", "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10076984": { "compartment": "compartment_5460", "id": "reaction_10076984", "reactome": "R-BTA-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696409", "species_113521" ], "products": [ "species_113548", "species_5693978", "species_113556" ], "modifiers": [ [ "species_10076981", "catalyst" ] ], "additional_components": [ "E1B8R9", "ENSBTAT00000018115" ] }, "reaction_10059533": { "compartment": "compartment_984", "id": "reaction_10059533", "reactome": "R-BTA-1564142", "name": "Collagen type IV degradation by MMP2,3,4,9,10,12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526" ], "products": [ "species_10058166" ], "modifiers": [ [ "species_10059530", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059598": { "compartment": "compartment_984", "id": "reaction_10059598", "reactome": "R-BTA-1564164", "name": "Collagen type V degradation by MMP2,9,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058699" ], "products": [ "species_10059595" ], "modifiers": [ [ "species_10059528", "catalyst" ] ], "additional_components": [ "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "ENSBTAT00000013124" ] }, "reaction_10058561": { "compartment": "compartment_984", "id": "reaction_10058561", "reactome": "R-BTA-1474197", "name": "Collagen type II degradation by MMP1,3,8,13,PRSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058552" ], "products": [ "species_10057938" ], "modifiers": [ [ "species_10058558", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059441": { "compartment": "compartment_984", "id": "reaction_10059441", "reactome": "R-BTA-1564112", "name": "Collagen type VI degradation by MMP2,9,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282" ], "products": [ "species_10059434" ], "modifiers": [ [ "species_10059438", "catalyst" ] ], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000008025" ] }, "reaction_10064705": { "compartment": "compartment_984", "id": "reaction_10064705", "reactome": "R-BTA-2168038", "name": "Collagen type XV restin release", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064651" ], "products": [ "species_10064677", "species_10064703" ], "modifiers": [], "additional_components": [ "A0A3Q1M0N0", "ENSBTAT00000072268", "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10058193": { "compartment": "compartment_984", "id": "reaction_10058193", "reactome": "R-BTA-1454757", "name": "Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058168" ], "products": [], "modifiers": [ [ "species_10058190", "catalyst" ] ], "additional_components": [ "P02459", "ENSBTAT00000017505", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "F1MU56", "ENSBTAT00000006029", "F1MT97", "ENSBTAT00000021014", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1M4A6", "ENSBTAT00000081947", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059651": { "compartment": "compartment_984", "id": "reaction_10059651", "reactome": "R-BTA-1564169", "name": "Collagen type VIII degradation by MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059648" ], "products": [ "species_10058052" ], "modifiers": [ [ "species_10058172", "catalyst" ] ], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "ENSBTAT00000021014" ] }, "reaction_10059689": { "compartment": "compartment_984", "id": "reaction_10059689", "reactome": "R-BTA-1592297", "name": "Full activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059684" ], "products": [ "species_10058172" ], "modifiers": [ [ "species_10059686", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "F1MU56", "ENSBTAT00000006029", "F1MMD4", "ENSBTAT00000008025", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059913": { "compartment": "compartment_984", "id": "reaction_10059913", "reactome": "R-BTA-1604712", "name": "Initial activation of proMMP7 by trypsin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059908", "species_10059906" ], "modifiers": [ [ "species_10059910", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "A7YWU9", "ENSBTAT00000028731" ] }, "reaction_10059787": { "compartment": "compartment_984", "id": "reaction_10059787", "reactome": "R-BTA-1592371", "name": "Initial activation of proMMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059746" ], "products": [ "species_10059750", "species_10059748" ], "modifiers": [ [ "species_10059784", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A7YWU6", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059869": { "compartment": "compartment_984", "id": "reaction_10059869", "reactome": "R-BTA-1602458", "name": "Activation of proMMP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059862" ], "products": [ "species_10059528" ], "modifiers": [ [ "species_10059866", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "E1B726", "ENSBTAT00000001674", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10059804": { "compartment": "compartment_984", "id": "reaction_10059804", "reactome": "R-BTA-1592398", "name": "Activation of proMMP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059793" ], "products": [ "species_10058188" ], "modifiers": [ [ "species_10059801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063400", "ENSBTAT00000063400", "A7YWU9", "ENSBTAT00000028731", "Q6H320", "ENSBTAT00000024677", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10059902": { "compartment": "compartment_984", "id": "reaction_10059902", "reactome": "R-BTA-1602473", "name": "Autocatalytic activation of MMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059706" ], "products": [ "species_10059684", "species_10059899" ], "modifiers": [ [ "species_10059706", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014" ] }, "reaction_10059918": { "compartment": "compartment_984", "id": "reaction_10059918", "reactome": "R-BTA-1604731", "name": "Autocatalytic activation of MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059748" ], "products": [ "species_10058180", "species_10059915" ], "modifiers": [ [ "species_10059748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124", "ENSBTAT00000013124" ] }, "reaction_10059744": { "compartment": "compartment_984", "id": "reaction_10059744", "reactome": "R-BTA-1592362", "name": "Activation of proMMP7 by MMP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059733" ], "products": [ "species_10059735", "species_10058184" ], "modifiers": [ [ "species_10059741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "P25975", "ENSBTAT00000036427", "F1MTX6", "ENSBTAT00000013124" ] }, "reaction_10059731": { "compartment": "compartment_984", "id": "reaction_10059731", "reactome": "R-BTA-1592316", "name": "Initial activation of proMMP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059704" ], "products": [ "species_10059708", "species_10059706" ], "modifiers": [ [ "species_10059728", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021014", "ENSBTAT00000021014", "ENSBTAT00000021014", "A7YWU9", "ENSBTAT00000028731", "Q2KJ63", "ENSBTAT00000012503", "A6QPI9", "ENSBTAT00000009636", "E1BAD2", "ENSBTAT00000054741", "G3MWP1", "ENSBTAT00000064480", "E1B726", "ENSBTAT00000001674", "E1B8U1", "ENSBTAT00000052512", "E1BIP7", "ENSBTAT00000011737" ] }, "reaction_10059923": { "compartment": "compartment_984", "id": "reaction_10059923", "reactome": "R-BTA-1604763", "name": "Autocatalytic activation of MMP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059906" ], "products": [ "species_10059920", "species_10058184" ], "modifiers": [ [ "species_10059906", "catalyst" ], [ "species_1604783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "ENSBTAT00000006029", "CHEBI:24505", "species_444761" ] }, "reaction_10060003": { "compartment": "compartment_17963", "id": "reaction_10060003", "reactome": "R-BTA-1605825", "name": "MT-MMPs are sorted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059897" ], "products": [ "species_10060001" ], "modifiers": [], "additional_components": [ "F1N797", "ENSBTAT00000061368", "F1N797", "ENSBTAT00000061368" ] }, "reaction_10068885": { "compartment": "compartment_984", "id": "reaction_10068885", "reactome": "R-BTA-3814820", "name": "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10068874", "species_10068872" ], "modifiers": [ [ "species_10068882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MF35", "ENSBTAT00000015593", "E1BEV7", "ENSBTAT00000001218", "A0A452DK38", "ENSBTAT00000036427", "F1N0X6", "ENSBTAT00000007834" ] }, "reaction_10065751": { "compartment": "compartment_984", "id": "reaction_10065751", "reactome": "R-BTA-2485148", "name": "Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063837" ], "products": [ "species_10065748" ], "modifiers": [ [ "species_10058176", "catalyst" ] ], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "ENSBTAT00000081947" ] }, "reaction_10087543": { "compartment": "compartment_876", "id": "reaction_10087543", "reactome": "R-BTA-8943987", "name": "SCUBE1, SCUBE3 oligomerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087535" ], "products": [ "species_10087541" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068477", "A0A3Q1MG91", "ENSBTAT00000068477" ] }, "reaction_10059702": { "compartment": "compartment_984", "id": "reaction_10059702", "reactome": "R-BTA-1592314", "name": "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693" ], "products": [ "species_10059697", "species_10059695" ], "modifiers": [ [ "species_10059699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022744", "ENSBTAT00000022744", "ENSBTAT00000022744", "F1MTX6", "ENSBTAT00000013124", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10061174": { "compartment": "compartment_876", "id": "reaction_10061174", "reactome": "R-BTA-1861621", "name": "Cross-linking of FCGRIIA with IgG-coated Ag", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061170", "species_10039426" ], "products": [ "species_10061172" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029116", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1MHH9", "ENSBTAT00000029116" ] }, "reaction_10033690": { "compartment": "compartment_5460", "id": "reaction_10033690", "reactome": "R-BTA-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113559", "species_113552" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10033687", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021616" ] }, "reaction_10033706": { "compartment": "compartment_70101", "id": "reaction_10033706", "reactome": "R-BTA-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29468" ], "products": [ "species_29514", "species_29498" ], "modifiers": [ [ "species_10033703", "catalyst" ] ], "additional_components": [ "species_113527", "Q2KJ64", "ENSBTAT00000016461" ] }, "reaction_10033770": { "compartment": "compartment_70101", "id": "reaction_10033770", "reactome": "R-BTA-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113567", "species_29498" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10033767", "catalyst" ] ], "additional_components": [ "Q2KHW4", "ENSBTAT00000015468", "A0A3Q1N1S4", "ENSBTAT00000015847" ] }, "reaction_10033697": { "compartment": "compartment_5460", "id": "reaction_10033697", "reactome": "R-BTA-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113561", "species_29896" ], "products": [ "species_113548", "species_113581", "species_29676" ], "modifiers": [ [ "species_10033694", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022158" ] }, "reaction_10084008": { "compartment": "compartment_70101", "id": "reaction_10084008", "reactome": "R-BTA-8852127", "name": "UBA6 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083994", "species_10083992" ], "products": [ "species_10084006", "species_10083996" ], "modifiers": [], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1ME38", "ENSBTAT00000008985", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "F1ME38", "ENSBTAT00000008985", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088" ] }, "reaction_10084122": { "compartment": "compartment_70101", "id": "reaction_10084122", "reactome": "R-BTA-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084119" ], "products": [ "species_10033406", "species_10033404", "species_10033402" ], "modifiers": [ [ "species_10075812", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000022919", "ENSBTAT00000026356" ] }, "reaction_10084113": { "compartment": "compartment_70101", "id": "reaction_10084113", "reactome": "R-BTA-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033394" ], "products": [ "species_10033394", "species_10034499" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087088", "ENSBTAT00000087088", "ENSBTAT00000087088", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10084117": { "compartment": "compartment_70101", "id": "reaction_10084117", "reactome": "R-BTA-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084115" ], "products": [ "species_10033398", "species_10034743" ], "modifiers": [ [ "species_10084110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010176", "ENSBTAT00000010176", "ENSBTAT00000010176", "F1N556", "ENSBTAT00000007177", "G5E630", "ENSBTAT00000050390" ] }, "reaction_10086702": { "compartment": "compartment_459", "id": "reaction_10086702", "reactome": "R-BTA-8939323", "name": "RNF181 binds BCL10 and Ubiquitin:E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086688", "species_10086698", "species_10043291" ], "products": [ "species_10086700" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10086710": { "compartment": "compartment_459", "id": "reaction_10086710", "reactome": "R-BTA-8939335", "name": "RNF181 polyubiquinates BCL10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086700", "species_10086698" ], "products": [ "species_10086707", "species_10086688", "species_10086705" ], "modifiers": [ [ "species_10086700", "catalyst" ] ], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1MAR8", "ENSBTAT00000084854", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "ENSBTAT00000024336", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "A0A3Q1MAR8", "ENSBTAT00000084854", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0W3", "ENSBTAT00000024336" ] }, "reaction_10047210": { "compartment": "compartment_984", "id": "reaction_10047210", "reactome": "R-BTA-390649", "name": "CHRM1,3,5 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045758", "species_372533" ], "products": [ "species_10045760" ], "modifiers": [], "additional_components": [ "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383" ] }, "reaction_10047214": { "compartment": "compartment_984", "id": "reaction_10047214", "reactome": "R-BTA-390673", "name": "CHRM2,4 bind acetylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046209", "species_372533" ], "products": [ "species_10046211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019534", "species_372533", "P41985", "ENSBTAT00000019534" ] }, "reaction_10047224": { "compartment": "compartment_984", "id": "reaction_10047224", "reactome": "R-BTA-390846", "name": "D2D3,4 bind to DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10046197" ], "products": [ "species_10046199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002768", "species_159362", "F1N454", "ENSBTAT00000002768" ] }, "reaction_10091556": { "compartment": "compartment_984", "id": "reaction_10091556", "reactome": "R-BTA-9656244", "name": "DRD2 binds DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10091552" ], "products": [ "species_10091554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014422", "F1N4I3", "ENSBTAT00000014422", "species_159362" ] }, "reaction_10047222": { "compartment": "compartment_984", "id": "reaction_10047222", "reactome": "R-BTA-390835", "name": "DRD1,5 bind DA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380873", "species_10047218" ], "products": [ "species_10047220" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062955", "Q95136", "ENSBTAT00000062955", "species_159362" ] }, "reaction_10091929": { "compartment": "compartment_984", "id": "reaction_10091929", "reactome": "R-BTA-9693347", "name": "HTR1A binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091925", "species_114523" ], "products": [ "species_10091927" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054712", "species_209914", "F6Q2H9", "ENSBTAT00000054712" ] }, "reaction_10047256": { "compartment": "compartment_984", "id": "reaction_10047256", "reactome": "R-BTA-390931", "name": "5-HT4, 6 and 7 receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047252", "species_114523" ], "products": [ "species_10047254" ], "modifiers": [], "additional_components": [ "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575", "species_209914", "A0A3Q1MLD1", "ENSBTAT00000067375", "E1BE22", "ENSBTAT00000010513", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10047236": { "compartment": "compartment_984", "id": "reaction_10047236", "reactome": "R-BTA-390929", "name": "HTR1 and 5A receptors can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114523", "species_10046185" ], "products": [ "species_10046187" ], "modifiers": [], "additional_components": [ "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914" ] }, "reaction_10047238": { "compartment": "compartment_984", "id": "reaction_10047238", "reactome": "R-BTA-390930", "name": "5-HT2 receptor can bind serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045782", "species_114523" ], "products": [ "species_10045784" ], "modifiers": [], "additional_components": [ "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796" ] }, "reaction_10047226": { "compartment": "compartment_984", "id": "reaction_10047226", "reactome": "R-BTA-390886", "name": "HRH4 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046191", "species_390899" ], "products": [ "species_10046193" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048201", "species_390899", "E1BBS2", "ENSBTAT00000048201" ] }, "reaction_10091825": { "compartment": "compartment_984", "id": "reaction_10091825", "reactome": "R-BTA-9692880", "name": "HRH3 binds Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390899", "species_10091821" ], "products": [ "species_10091823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020802", "F1MML8", "ENSBTAT00000020802", "species_390899" ] }, "reaction_10047234": { "compartment": "compartment_984", "id": "reaction_10047234", "reactome": "R-BTA-390909", "name": "HRH2 binds hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047230", "species_390899" ], "products": [ "species_10047232" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061359", "species_390899", "E1BK27", "ENSBTAT00000061359" ] }, "reaction_10090968": { "compartment": "compartment_984", "id": "reaction_10090968", "reactome": "R-BTA-9611852", "name": "ADRB3 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051599" ], "products": [ "species_10051601" ], "modifiers": [ [ "species_10090958", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000085511", "CHEBI:28918", "species_209789", "A0A3Q1MQZ8", "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090925": { "compartment": "compartment_984", "id": "reaction_10090925", "reactome": "R-BTA-9609310", "name": "-blockers bind ADRB1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9609307", "species_10090921" ], "products": [ "species_10090923" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047212": { "compartment": "compartment_984", "id": "reaction_10047212", "reactome": "R-BTA-390663", "name": "ADRA2A,B,C bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10090960": { "compartment": "compartment_984", "id": "reaction_10090960", "reactome": "R-BTA-9611839", "name": "3-agonists bind ADRB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611836", "species_10051599" ], "products": [ "species_10090958" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085511", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10090964": { "compartment": "compartment_984", "id": "reaction_10090964", "reactome": "R-BTA-9611851", "name": "ADRB2 bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10051593" ], "products": [ "species_10051595" ], "modifiers": [ [ "species_10090962", "catalyst" ], [ "species_10090923", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "Q28044", "ENSBTAT00000002779", "A0A3Q1MQZ8", "ENSBTAT00000085511" ] }, "reaction_10047206": { "compartment": "compartment_984", "id": "reaction_10047206", "reactome": "R-BTA-390641", "name": "ADRA1A,B,D bind ADR,NAd", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10045770" ], "products": [ "species_10045772" ], "modifiers": [ [ "species_10047204", "catalyst" ], [ "species_10047202", "inhibitor" ] ], "additional_components": [ "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443" ] }, "reaction_10047332": { "compartment": "compartment_984", "id": "reaction_10047332", "reactome": "R-BTA-391211", "name": "Trace amine-associated receptors can bind trace amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047328", "species_391200" ], "products": [ "species_10047330" ], "modifiers": [], "additional_components": [ "F1N0G5", "ENSBTAT00000054907", "species_391200", "F1N0G5", "ENSBTAT00000054907" ] }, "reaction_10083878": { "compartment": "compartment_876", "id": "reaction_10083878", "reactome": "R-BTA-8851298", "name": "GPR143 binds L-Dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851314", "species_10046122" ], "products": [ "species_10046124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008485", "G5E581", "ENSBTAT00000008485", "species_8851314" ] }, "reaction_10038450": { "compartment": "compartment_70101", "id": "reaction_10038450", "reactome": "R-BTA-162425", "name": "p-S295-PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10038447", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10036570": { "compartment": "compartment_70101", "id": "reaction_10036570", "reactome": "R-BTA-109699", "name": "PI3K-containing complexes phosphorylate PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10036567", "catalyst" ] ], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "G3XGD3", "ENSBTAT00000029946", "E1BHC1", "ENSBTAT00000016675", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LRU7", "ENSBTAT00000072473", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1M3Q3", "ENSBTAT00000073054", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10036607": { "compartment": "compartment_70101", "id": "reaction_10036607", "reactome": "R-BTA-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10036588" ], "products": [ "species_29370", "species_10036604" ], "modifiers": [ [ "species_10036596", "catalyst" ] ], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036590": { "compartment": "compartment_876", "id": "reaction_10036590", "reactome": "R-BTA-109700", "name": "AKT2 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036586" ], "products": [ "species_10036580", "species_10036588" ], "modifiers": [], "additional_components": [ "A0A3Q1NH21", "ENSBTAT00000076493", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "E1BA10", "ENSBTAP00000020594", "Q0VCE3", "ENSBTAT00000022616", "A0A3Q1NH21", "ENSBTAT00000076493", "species_179838" ] }, "reaction_10036598": { "compartment": "compartment_876", "id": "reaction_10036598", "reactome": "R-BTA-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10036594" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10035507": { "compartment": "compartment_70101", "id": "reaction_10035507", "reactome": "R-BTA-74736", "name": "GRB2-1:SOS1 binds p-IRS1,p-IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035503" ], "products": [ "species_10035505" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10035527": { "compartment": "compartment_70101", "id": "reaction_10035527", "reactome": "R-BTA-74737", "name": "p-Y-IRS1,p-Y-IRS2 bind PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10035503" ], "products": [ "species_10035525" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10055817": { "compartment": "compartment_12045", "id": "reaction_10055817", "reactome": "R-BTA-983424", "name": "Budding of COPII coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055815" ], "products": [ "species_10055805" ], "modifiers": [], "additional_components": [ "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10043659": { "compartment": "compartment_12045", "id": "reaction_10043659", "reactome": "R-BTA-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580" ], "products": [ "species_10043657" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055819": { "compartment": "compartment_12045", "id": "reaction_10055819", "reactome": "R-BTA-983426", "name": "Capturing cargo and formation of prebudding complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054858", "species_10043657" ], "products": [ "species_10055813" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10055821": { "compartment": "compartment_876", "id": "reaction_10055821", "reactome": "R-BTA-983427", "name": "Expression of peptide bound class I MHC on cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055781" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10087807": { "compartment": "compartment_453088", "id": "reaction_10087807", "reactome": "R-BTA-8951499", "name": "Loading of antigenic peptides on to class I MHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055472", "species_983033" ], "products": [ "species_10055474" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "species_1236727", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "Q2NL04", "ENSBTAT00000022386", "Q5E9F1", "ENSBTAT00000068015", "A5D7J6", "ENSBTAT00000020111", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10054866": { "compartment": "compartment_453088", "id": "reaction_10054866", "reactome": "R-BTA-983138", "name": "Transport of MHC heterotrimer to ER exit site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054864" ], "products": [ "species_10054862", "species_10054858" ], "modifiers": [], "additional_components": [ "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727", "Q5E9F1", "ENSBTAT00000068015", "Q5E9F1", "ENSBTAT00000068015", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "species_1236727" ] }, "reaction_10055444": { "compartment": "compartment_17957", "id": "reaction_10055444", "reactome": "R-BTA-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_983032" ], "products": [ "species_29372", "species_29370", "species_983034" ], "modifiers": [ [ "species_10055441", "catalyst" ] ], "additional_components": [ "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751" ] }, "reaction_10055460": { "compartment": "compartment_17957", "id": "reaction_10055460", "reactome": "R-BTA-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_8943716", "species_983033" ], "modifiers": [ [ "species_10055457", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078466" ] }, "reaction_10055783": { "compartment": "compartment_13945", "id": "reaction_10055783", "reactome": "R-BTA-983421", "name": "Journey of cargo through Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055715" ], "products": [ "species_10055781" ], "modifiers": [], "additional_components": [ "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "CHEBI:59080", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "CHEBI:59080", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10039485": { "compartment": "compartment_947587", "id": "reaction_10039485", "reactome": "R-BTA-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10036954" ], "products": [ "species_29438", "species_10037043" ], "modifiers": [ [ "species_10036952", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160" ] }, "reaction_10037641": { "compartment": "compartment_70101", "id": "reaction_10037641", "reactome": "R-BTA-139898", "name": "Caspase-8 activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037731": { "compartment": "compartment_70101", "id": "reaction_10037731", "reactome": "R-BTA-139920", "name": "Translocation of tBID to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037729" ], "products": [ "species_10037269" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737" ] }, "reaction_10037618": { "compartment": "compartment_70101", "id": "reaction_10037618", "reactome": "R-BTA-139893", "name": "Granzyme-B activates BID by cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037609" ], "products": [ "species_10037611" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000013262" ] }, "reaction_10038007": { "compartment": "compartment_70101", "id": "reaction_10038007", "reactome": "R-BTA-141367", "name": "Myristoylation of tBID by NMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037611" ], "products": [ "species_10037729" ], "modifiers": [ [ "species_10038004", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000007950" ] }, "reaction_10049615": { "compartment": "compartment_984", "id": "reaction_10049615", "reactome": "R-BTA-444171", "name": "Receptor FFAR2 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046048", "species_444210" ], "products": [ "species_10046050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008619", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:17120", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJV9", "ENSBTAT00000008619" ] }, "reaction_10049617": { "compartment": "compartment_984", "id": "reaction_10049617", "reactome": "R-BTA-444202", "name": "Receptor FFAR1 binds free fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10049585": { "compartment": "compartment_984", "id": "reaction_10049585", "reactome": "R-BTA-444047", "name": "Receptor FFAR3 binds carboxylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046054", "species_444074" ], "products": [ "species_10046056" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053502", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502" ] }, "reaction_10067360": { "compartment": "compartment_876", "id": "reaction_10067360", "reactome": "R-BTA-3296304", "name": "GPR31 is a receptor for 12(S)-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296298", "species_10046489" ], "products": [ "species_10046491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019274", "F1N1J4", "ENSBTAT00000019274", "species_3296298" ] }, "reaction_10041453": { "compartment": "compartment_984", "id": "reaction_10041453", "reactome": "R-BTA-194308", "name": "VEGF-C,D bind to VEGFR3 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041447", "species_10041443" ], "products": [ "species_10041451" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613", "F1MHP5", "ENSBTAT00000040219", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10041463": { "compartment": "compartment_984", "id": "reaction_10041463", "reactome": "R-BTA-194310", "name": "VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041443", "species_10041457" ], "products": [ "species_10041461" ], "modifiers": [], "additional_components": [ "Q9XS50", "ENSBTAT00000019613", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10040328": { "compartment": "compartment_70101", "id": "reaction_10040328", "reactome": "R-BTA-177944", "name": "Activation of SHP2 through the binding to phospho-Gab1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10040245" ], "products": [ "species_10040247" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040299": { "compartment": "compartment_70101", "id": "reaction_10040299", "reactome": "R-BTA-177935", "name": "SHP2 dephosphorylates Tyr 992 on EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040297" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040267": { "compartment": "compartment_70101", "id": "reaction_10040267", "reactome": "R-BTA-177926", "name": "Dephosphorylation of PAG by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040263", "species_29356" ], "products": [ "species_29372", "species_10040265" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067689", "ENSBTAT00000067689", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040254": { "compartment": "compartment_70101", "id": "reaction_10040254", "reactome": "R-BTA-177924", "name": "Dephosphorylation of Gab1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040247", "species_29356" ], "products": [ "species_29372", "species_10040251" ], "modifiers": [ [ "species_10040247", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10040277": { "compartment": "compartment_70101", "id": "reaction_10040277", "reactome": "R-BTA-177930", "name": "GAB1 phosphorylation by EGFR kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040271" ], "products": [ "species_10040245", "species_29370" ], "modifiers": [ [ "species_10040271", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10043129": { "compartment": "compartment_876", "id": "reaction_10043129", "reactome": "R-BTA-201677", "name": "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043120", "species_113592" ], "products": [ "species_10043126", "species_29370" ], "modifiers": [ [ "species_10043120", "catalyst" ] ], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1N1K8", "ENSBTAT00000007756", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10071320": { "compartment": "compartment_70101", "id": "reaction_10071320", "reactome": "R-BTA-5323526", "name": "FRAT proteins bind GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041625" ], "products": [ "species_10041627" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10059152": { "compartment": "compartment_70101", "id": "reaction_10059152", "reactome": "R-BTA-1504186", "name": "DVL recruits GSK3beta:AXIN1 to the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043061", "species_10043118" ], "products": [ "species_10043120" ], "modifiers": [], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BEN9", "ENSBTAT00000020414", "E1BKL2", "ENSBTAT00000035270", "F1MHG3", "ENSBTAT00000017163", "A7MB15", "ENSBTAT00000002720", "G3N2W8", "ENSBTAT00000027434", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10083835": { "compartment": "compartment_984", "id": "reaction_10083835", "reactome": "R-BTA-8850831", "name": "KLK5 cleaves and activates KLK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10083828" ], "products": [ "species_10083830", "species_10083832" ], "modifiers": [ [ "species_10083733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000020127", "ENSBTAT00000070524" ] }, "reaction_10083741": { "compartment": "compartment_984", "id": "reaction_10083741", "reactome": "R-BTA-8849638", "name": "Dissociation of the SPINK5:KLK5 complex at low pH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083739" ], "products": [ "species_10083733", "species_10083737" ], "modifiers": [ [ "species_351626", "catalyst" ] ], "additional_components": [ "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524", "ENSBTAT00000070524", "ENSBTAT00000025479" ] }, "reaction_10083743": { "compartment": "compartment_984", "id": "reaction_10083743", "reactome": "R-BTA-8849646", "name": "SPINK5(490-624) binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083737" ], "products": [ "species_10083739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000025479", "F1MJH0", "ENSBTAT00000025479", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10083824": { "compartment": "compartment_984", "id": "reaction_10083824", "reactome": "R-BTA-8850818", "name": "SPINK9 binds KLK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083733", "species_10083820" ], "products": [ "species_10083822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070524", "ENSBTAT00000081553", "A0A3Q1NK79", "ENSBTAT00000081553", "E1BGD9", "ENSBTAT00000070524" ] }, "reaction_10077943": { "compartment": "compartment_984", "id": "reaction_10077943", "reactome": "R-BTA-6789310", "name": "LIPs hydrolyse TG to DAG and RCOOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174675", "species_6789319" ], "modifiers": [ [ "species_10077940", "catalyst" ] ], "additional_components": [ "E1BA50", "ENSBTAT00000017778", "G3MVZ9", "ENSBTAT00000034704" ] }, "reaction_10084466": { "compartment": "compartment_70101", "id": "reaction_10084466", "reactome": "R-BTA-8857577", "name": "LINC01139 facilitates PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084458" ], "products": [ "species_29370", "species_10084463" ], "modifiers": [ [ "species_10084458", "catalyst" ] ], "additional_components": [ "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "E1BPU0", "ENSBTAT00000061570", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10090009": { "compartment": "compartment_876", "id": "reaction_10090009", "reactome": "R-BTA-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090005", "species_10089989" ], "products": [ "species_10090007" ], "modifiers": [], "additional_components": [ "A0A3Q1MD15", "ENSBTAT00000079650", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MD15", "ENSBTAT00000079650" ] }, "reaction_10091896": { "compartment": "compartment_17906", "id": "reaction_10091896", "reactome": "R-BTA-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091892", "species_10091882" ], "products": [ "species_10091894" ], "modifiers": [], "additional_components": [ "F1MY55", "ENSBTAT00000023513", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1MY55", "ENSBTAT00000023513" ] }, "reaction_10090011": { "compartment": "compartment_876", "id": "reaction_10090011", "reactome": "R-BTA-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10089989" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091884": { "compartment": "compartment_876", "id": "reaction_10091884", "reactome": "R-BTA-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091882" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091916": { "compartment": "compartment_20699", "id": "reaction_10091916", "reactome": "R-BTA-9693250", "name": "RHOD binds effectors at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091900", "species_10091912" ], "products": [ "species_10091914" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "A0A3Q1MZP2", "ENSBTAT00000081390", "A0A3Q1MZP2", "ENSBTAT00000081390", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10091902": { "compartment": "compartment_876", "id": "reaction_10091902", "reactome": "R-BTA-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089969" ], "products": [ "species_10091900" ], "modifiers": [], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438" ] }, "reaction_10089985": { "compartment": "compartment_876", "id": "reaction_10089985", "reactome": "R-BTA-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10089969" ], "products": [ "species_29372", "species_10089965" ], "modifiers": [ [ "species_10089982", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089972": { "compartment": "compartment_876", "id": "reaction_10089972", "reactome": "R-BTA-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089965" ], "products": [ "species_29420", "species_10089969" ], "modifiers": [ [ "species_10089965", "catalyst" ] ], "additional_components": [ "F1N7C7", "ENSBTAT00000027446", "species_29420", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29420" ] }, "reaction_10091878": { "compartment": "compartment_70101", "id": "reaction_10091878", "reactome": "R-BTA-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091874", "species_10089969" ], "products": [ "species_10091876" ], "modifiers": [], "additional_components": [ "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009", "F1N7C7", "ENSBTAT00000027446", "species_29438", "F1N7C7", "ENSBTAT00000027446", "species_29438", "E1BAJ4", "ENSBTAT00000013713", "A5D7A0", "ENSBTAT00000044780", "P79132", "ENSBTAT00000023751", "A0A3Q1LNG7", "ENSBTAT00000075973", "A0A3Q1LR88", "ENSBTAT00000066654", "A0JN43", "ENSBTAT00000044160", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LPT9", "ENSBTAT00000077862", "A0A3Q1NDE1", "ENSBTAT00000086993", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1MSB2", "ENSBTAT00000070687", "A0A3Q1LNB6", "ENSBTAT00000070608", "E1BHQ9", "ENSBTAT00000047009" ] }, "reaction_10057177": { "compartment": "compartment_876", "id": "reaction_10057177", "reactome": "R-BTA-1250357", "name": "SHC1 binds P-ERBB4 isoform dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057163", "species_10035544" ], "products": [ "species_10057170" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057188": { "compartment": "compartment_876", "id": "reaction_10057188", "reactome": "R-BTA-1250380", "name": "Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057172", "species_10035491" ], "products": [ "species_10057186" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057175": { "compartment": "compartment_876", "id": "reaction_10057175", "reactome": "R-BTA-1250348", "name": "Phosphorylation of SHC1 by ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057170", "species_113592" ], "products": [ "species_10057172", "species_29370" ], "modifiers": [ [ "species_10057170", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057191": { "compartment": "compartment_70101", "id": "reaction_10057191", "reactome": "R-BTA-1250383", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057186", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10083712": { "compartment": "compartment_20699", "id": "reaction_10083712", "reactome": "R-BTA-8849345", "name": "LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_8848483" ], "products": [ "species_429785", "species_76194" ], "modifiers": [ [ "species_10083709", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087371" ] }, "reaction_10083004": { "compartment": "compartment_20699", "id": "reaction_10083004", "reactome": "R-BTA-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10082997" ], "products": [ "species_29420", "species_10083001" ], "modifiers": [ [ "species_10082997", "catalyst" ] ], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10083006": { "compartment": "compartment_20699", "id": "reaction_10083006", "reactome": "R-BTA-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082993" ], "products": [ "species_10082995" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082999": { "compartment": "compartment_20699", "id": "reaction_10082999", "reactome": "R-BTA-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082995" ], "products": [ "species_10082997" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10049867": { "compartment": "compartment_12045", "id": "reaction_10049867", "reactome": "R-BTA-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_29420", "species_449283" ], "modifiers": [ [ "species_10049864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002836" ] }, "reaction_10049851": { "compartment": "compartment_12045", "id": "reaction_10049851", "reactome": "R-BTA-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10049848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003187" ] }, "reaction_10049789": { "compartment": "compartment_17957", "id": "reaction_10049789", "reactome": "R-BTA-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449298" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10049782", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000032212", "ENSBTAT00000000147" ] }, "reaction_10049811": { "compartment": "compartment_17957", "id": "reaction_10049811", "reactome": "R-BTA-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449312" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10049808", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064352", "ENSBTAT00000000147" ] }, "reaction_10049858": { "compartment": "compartment_17957", "id": "reaction_10049858", "reactome": "R-BTA-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449315" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10082941": { "compartment": "compartment_70101", "id": "reaction_10082941", "reactome": "R-BTA-6810464", "name": "NUDT14 hydrolyses UDP-Glc to G1P and UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410" ], "products": [ "species_29548", "species_109402" ], "modifiers": [ [ "species_10082938", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063951" ] }, "reaction_10077816": { "compartment": "compartment_70101", "id": "reaction_10077816", "reactome": "R-BTA-6787623", "name": "TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787618" ], "products": [ "species_6787646" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10077800": { "compartment": "compartment_70101", "id": "reaction_10077800", "reactome": "R-BTA-6787533", "name": "FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_6787542" ], "products": [ "species_111294", "species_742368" ], "modifiers": [ [ "species_10077797", "catalyst" ] ], "additional_components": [ "ENSBTAT00000055149" ] }, "reaction_10077823": { "compartment": "compartment_70101", "id": "reaction_10077823", "reactome": "R-BTA-6787632", "name": "GMDS dehydrates GDP-Man to GDP-DHDMan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860" ], "products": [ "species_29356", "species_6787618" ], "modifiers": [ [ "species_10077820", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015992" ] }, "reaction_10077807": { "compartment": "compartment_70101", "id": "reaction_10077807", "reactome": "R-BTA-6787540", "name": "FUK phosphorylates beta-Fuc to Fuc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6787678" ], "products": [ "species_29370", "species_6787542" ], "modifiers": [ [ "species_10077804", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085459" ] }, "reaction_10077826": { "compartment": "compartment_70101", "id": "reaction_10077826", "reactome": "R-BTA-6787642", "name": "TSTA3 dimer reduces GDP-KDGal to GDP-Fuc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6787646", "species_29364" ], "products": [ "species_742368", "species_29366" ], "modifiers": [ [ "species_10077813", "catalyst" ] ], "additional_components": [ "A0A3Q1M2A1", "ENSBTAT00000082106" ] }, "reaction_10049831": { "compartment": "compartment_70101", "id": "reaction_10049831", "reactome": "R-BTA-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10049828", "catalyst" ] ], "additional_components": [ "Q0VC17", "ENSBTAT00000076692", "Q3SZJ9", "ENSBTAT00000001888" ] }, "reaction_10069368": { "compartment": "compartment_70101", "id": "reaction_10069368", "reactome": "R-BTA-4085021", "name": "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_162756" ], "products": [ "species_110096", "species_4085214" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069320": { "compartment": "compartment_70101", "id": "reaction_10069320", "reactome": "R-BTA-4084976", "name": "NANS converts ManNAc-6-P to Neu5Ac-9-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085225", "species_29492" ], "products": [ "species_29372", "species_4085390" ], "modifiers": [ [ "species_10069317", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025318" ] }, "reaction_10069371": { "compartment": "compartment_70101", "id": "reaction_10069371", "reactome": "R-BTA-4085028", "name": "GNE phosphorylates ManNAc to ManNAc-6-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_4085214" ], "products": [ "species_29370", "species_4085225" ], "modifiers": [ [ "species_10069365", "catalyst" ] ], "additional_components": [ "F1MIL9", "ENSBTAT00000001520" ] }, "reaction_10069357": { "compartment": "compartment_70101", "id": "reaction_10069357", "reactome": "R-BTA-4084989", "name": "NANP dephosphorylates Neu5Ac-9-P to Neu5Ac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4085390" ], "products": [ "species_428633", "species_29372" ], "modifiers": [ [ "species_10069354", "catalyst" ] ], "additional_components": [ "A7YWM8", "ENSBTAT00000000918", "species_29926" ] }, "reaction_10069373": { "compartment": "compartment_70101", "id": "reaction_10069373", "reactome": "R-BTA-4085029", "name": "NEU2 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088202" ], "products": [ "species_428633", "species_4088123" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "species_4086294", "species_4086341", "species_4087982", "species_4086277", "species_4088006", "species_4086285", "species_4086301", "ENSBTAT00000027552" ] }, "reaction_10069359": { "compartment": "compartment_70101", "id": "reaction_10069359", "reactome": "R-BTA-4084994", "name": "NEU3 hydrolyzes Neu5Ac from glycoconjugates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_4088088" ], "products": [ "species_428633", "species_4088103" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "species_4086277", "species_4087982", "species_4088006", "species_4086285", "ENSBTAT00000036738" ] }, "reaction_10048958": { "compartment": "compartment_17938", "id": "reaction_10048958", "reactome": "R-BTA-428585", "name": "SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_428639" ], "products": [ "species_428633", "species_70106" ], "modifiers": [ [ "species_10048955", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061225" ] }, "reaction_10069329": { "compartment": "compartment_20699", "id": "reaction_10069329", "reactome": "R-BTA-4084978", "name": "ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4088006" ], "products": [ "species_727810", "species_4087982" ], "modifiers": [ [ "species_10069326", "catalyst" ] ], "additional_components": [ "A0A3Q1N8K2", "ENSBTAT00000074715", "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10051554": { "compartment": "compartment_20699", "id": "reaction_10051554", "reactome": "R-BTA-727807", "name": "SLC35A1 exchanges CMP-Neu5Ac for CMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727810", "species_4085435" ], "products": [ "species_727815", "species_109395" ], "modifiers": [ [ "species_10051551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018680" ] }, "reaction_10069346": { "compartment": "compartment_20699", "id": "reaction_10069346", "reactome": "R-BTA-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086301" ], "products": [ "species_4086341", "species_727810" ], "modifiers": [ [ "species_10069343", "catalyst" ] ], "additional_components": [ "F1MXN8", "ENSBTAT00000009616", "G3N3B2", "ENSBTAT00000063122", "A0A452DJH9", "ENSBTAT00000061027", "A0A3Q1LRX1", "ENSBTAT00000078008", "F1N6V7", "ENSBTAT00000034693" ] }, "reaction_10069348": { "compartment": "compartment_17963", "id": "reaction_10069348", "reactome": "R-BTA-4084984", "name": "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_4086277", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10069382": { "compartment": "compartment_20699", "id": "reaction_10069382", "reactome": "R-BTA-4085033", "name": "ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_4086285" ], "products": [ "species_727810", "species_4086294" ], "modifiers": [ [ "species_10069379", "catalyst" ] ], "additional_components": [ "A0A3Q1M347", "ENSBTAT00000083430", "A5D7T4", "ENSBTAT00000070130" ] }, "reaction_10069498": { "compartment": "compartment_12045", "id": "reaction_10069498", "reactome": "R-BTA-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419981", "species_29364" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10069495", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019855" ] }, "reaction_10049818": { "compartment": "compartment_12045", "id": "reaction_10049818", "reactome": "R-BTA-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449744" ], "products": [ "species_29372", "species_449299" ], "modifiers": [ [ "species_10049815", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023834" ] }, "reaction_10049804": { "compartment": "compartment_12045", "id": "reaction_10049804", "reactome": "R-BTA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_449221" ], "products": [ "species_110094", "species_449299" ], "modifiers": [ [ "species_10049801", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014016" ] }, "reaction_10040933": { "compartment": "compartment_70101", "id": "reaction_10040933", "reactome": "R-BTA-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29372", "species_29370", "species_113528", "species_191362" ], "modifiers": [ [ "species_10040930", "catalyst" ] ], "additional_components": [ "Q0P570", "ENSBTAT00000015994" ] }, "reaction_10049797": { "compartment": "compartment_12045", "id": "reaction_10049797", "reactome": "R-BTA-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449299" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10049794", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070574" ] }, "reaction_10049844": { "compartment": "compartment_12045", "id": "reaction_10049844", "reactome": "R-BTA-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_449222" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10049841", "catalyst" ] ], "additional_components": [ "F1MU60", "ENSBTAT00000006020", "A0A3Q1MW72", "ENSBTAT00000076761" ] }, "reaction_10049860": { "compartment": "compartment_17957", "id": "reaction_10049860", "reactome": "R-BTA-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449371", "species_449311" ], "modifiers": [ [ "species_10049855", "catalyst" ], [ "species_10049787", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052671", "ENSBTAT00000000147" ] }, "reaction_10056074": { "compartment": "compartment_20699", "id": "reaction_10056074", "reactome": "R-BTA-1022133", "name": "ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10056071", "catalyst" ] ], "additional_components": [ "A0A3Q1LM08", "ENSBTAT00000077891", "A0A3Q1LZS9", "ENSBTAT00000068182" ] }, "reaction_10056061": { "compartment": "compartment_20699", "id": "reaction_10056061", "reactome": "R-BTA-1022129", "name": "ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075324" ] }, "reaction_10054431": { "compartment": "compartment_20699", "id": "reaction_10054431", "reactome": "R-BTA-975903", "name": "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981616" ], "modifiers": [ [ "species_10054428", "catalyst" ] ], "additional_components": [ "E1BNB2", "ENSBTAT00000014809", "A6QQ63", "ENSBTAT00000049734" ] }, "reaction_10054467": { "compartment": "compartment_20699", "id": "reaction_10054467", "reactome": "R-BTA-975919", "name": "Addition of galactose by beta 4-galactosyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_975910" ], "products": [ "species_981618" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10054418": { "compartment": "compartment_20699", "id": "reaction_10054418", "reactome": "R-BTA-975902", "name": "ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975925", "species_975910" ], "products": [ "species_981615" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083430" ] }, "reaction_10054438": { "compartment": "compartment_20699", "id": "reaction_10054438", "reactome": "R-BTA-975916", "name": "Addition of GlcNAc to position 5 by MGAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981617" ], "modifiers": [ [ "species_10054435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084669" ] }, "reaction_10054474": { "compartment": "compartment_17963", "id": "reaction_10054474", "reactome": "R-BTA-975926", "name": "Addition of a bifurcating GlcNAc to the N-glycan by MGAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975910" ], "products": [ "species_981613" ], "modifiers": [ [ "species_10054471", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016591" ] }, "reaction_10054411": { "compartment": "compartment_20699", "id": "reaction_10054411", "reactome": "R-BTA-975829", "name": "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_975819" ], "products": [ "species_205687", "species_975822" ], "modifiers": [ [ "species_10054408", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048092" ] }, "reaction_10076415": { "compartment": "compartment_161320", "id": "reaction_10076415", "reactome": "R-BTA-5693807", "name": "FUCA1 hydrolyses NGP:1,6-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6784247" ], "products": [ "species_6784248", "species_6784249" ], "modifiers": [ [ "species_10076412", "catalyst" ] ], "additional_components": [ "Q2KIM0", "ENSBTAT00000042970" ] }, "reaction_10077710": { "compartment": "compartment_20699", "id": "reaction_10077710", "reactome": "R-BTA-6786034", "name": "CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10077694" ], "products": [ "species_10077703", "species_742343" ], "modifiers": [ [ "species_10077707", "catalyst" ] ], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000064164" ] }, "reaction_10077717": { "compartment": "compartment_20699", "id": "reaction_10077717", "reactome": "R-BTA-6786048", "name": "CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_6786371" ], "products": [ "species_742343", "species_6786380" ], "modifiers": [ [ "species_10077714", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082120" ] }, "reaction_10076422": { "compartment": "compartment_17963", "id": "reaction_10076422", "reactome": "R-BTA-5693925", "name": "FUT3 transfers L-fucose to Gal1,3GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693930", "species_205683" ], "products": [ "species_5693933", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10076696": { "compartment": "compartment_12045", "id": "reaction_10076696", "reactome": "R-BTA-5694433", "name": "MIA2 binds PREB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076692", "species_10043646" ], "products": [ "species_10076694" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078548", "ENSBTAT00000009307", "E1BL12", "ENSBTAT00000009307", "A0A3Q1LM15", "ENSBTAT00000078548" ] }, "reaction_10076586": { "compartment": "compartment_12045", "id": "reaction_10076586", "reactome": "R-BTA-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043590", "species_10043594", "species_10043592" ], "products": [ "species_10043596" ], "modifiers": [], "additional_components": [ "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "ENSBTAT00000004831", "ENSBTAT00000004721", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561" ] }, "reaction_10076590": { "compartment": "compartment_12045", "id": "reaction_10076590", "reactome": "R-BTA-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10043651", "species_10043594" ], "products": [ "species_10076588" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "ENSBTAT00000043111", "ENSBTAT00000004831", "A6QNT8", "ENSBTAT00000043111", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MVW5", "ENSBTAT00000004831" ] }, "reaction_10076706": { "compartment": "compartment_12045", "id": "reaction_10076706", "reactome": "R-BTA-5694442", "name": "CNIH2,3 bind GRIA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043622", "species_10043618" ], "products": [ "species_10043624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082647", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647" ] }, "reaction_10076708": { "compartment": "compartment_12045", "id": "reaction_10076708", "reactome": "R-BTA-5694445", "name": "CNIH1 binds TFGA and AREG precursors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043606", "species_10043600" ], "products": [ "species_10043608" ], "modifiers": [], "additional_components": [ "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "ENSBTAT00000025975", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129" ] }, "reaction_10076775": { "compartment": "compartment_12045", "id": "reaction_10076775", "reactome": "R-BTA-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043655", "species_10043580", "species_10043626" ], "products": [ "species_10043628" ], "modifiers": [], "additional_components": [ "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076584": { "compartment": "compartment_13959", "id": "reaction_10076584", "reactome": "R-BTA-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10076577" ], "products": [ "species_10076581", "species_29420" ], "modifiers": [ [ "species_10076577", "catalyst" ] ], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10076635": { "compartment": "compartment_70101", "id": "reaction_10076635", "reactome": "R-BTA-5694421", "name": "PP6 dephosphorylates SEC24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10076618" ], "products": [ "species_29372", "species_10043653" ], "modifiers": [ [ "species_10076632", "catalyst" ] ], "additional_components": [ "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "E1BN43", "ENSBTAT00000034553", "Q2KIC7", "ENSBTAT00000010568", "G3N214", "ENSBTAT00000066016" ] }, "reaction_10076778": { "compartment": "compartment_70101", "id": "reaction_10076778", "reactome": "R-BTA-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043628" ], "products": [ "species_10043655", "species_29372", "species_10043626", "species_10043642" ], "modifiers": [ [ "species_10043628", "catalyst" ] ], "additional_components": [ "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MVW5", "ENSBTAT00000004831", "F1MV07", "ENSBTAT00000004721", "A6QNT8", "ENSBTAT00000043111", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111" ] }, "reaction_10076698": { "compartment": "compartment_13959", "id": "reaction_10076698", "reactome": "R-BTA-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076575", "species_10076493", "species_10076537" ], "products": [ "species_10076577" ], "modifiers": [], "additional_components": [ "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509" ] }, "reaction_10043649": { "compartment": "compartment_70101", "id": "reaction_10043649", "reactome": "R-BTA-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043642" ], "products": [ "species_29420", "species_10043580" ], "modifiers": [ [ "species_10043646", "catalyst" ] ], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29420", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "ENSBTAT00000009307" ] }, "reaction_10083377": { "compartment": "compartment_6791047", "id": "reaction_10083377", "reactome": "R-BTA-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082020", "species_10083373" ], "products": [ "species_10083375" ], "modifiers": [], "additional_components": [ "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10076736": { "compartment": "compartment_6791047", "id": "reaction_10076736", "reactome": "R-BTA-5694446", "name": "BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076704", "species_10076667" ], "products": [ "species_10076596", "species_10076677", "species_10076734", "species_10076602" ], "modifiers": [], "additional_components": [ "A0A3Q1MMA1", "ENSBTAT00000066705", "P41541", "ENSBTAT00000022642", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1MJE3", "ENSBTAT00000082298", "A0A3Q1NDZ1", "ENSBTAT00000083081", "E1BG76", "ENSBTAT00000046085", "A0A3Q1MMA1", "ENSBTAT00000066705", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q5BIN6", "ENSBTAT00000025975", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "P41541", "ENSBTAT00000022642" ] }, "reaction_10076610": { "compartment": "compartment_20699", "id": "reaction_10076610", "reactome": "R-BTA-5694418", "name": "RAB1:GTP binds USO1 and GORASP1:GOLGA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076596", "species_10076581", "species_10076602" ], "products": [ "species_10076608" ], "modifiers": [], "additional_components": [ "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q3ZCC9", "ENSBTAT00000023702", "E1BKW5", "ENSBTAT00000009785", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "F1MEV4", "ENSBTAT00000024140", "A0A3Q1M7J4", "ENSBTAT00000085129", "Q5BIN6", "ENSBTAT00000025975", "A0A3Q1NDZ1", "ENSBTAT00000083081", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1LUP7", "ENSBTAT00000076684", "A0A3Q1N355", "ENSBTAT00000081836", "G0T3G6", "ENSBTAT00000082647", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10083380": { "compartment": "compartment_6791047", "id": "reaction_10083380", "reactome": "R-BTA-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083375" ], "products": [ "species_10083373", "species_10076493" ], "modifiers": [ [ "species_10083375", "catalyst" ] ], "additional_components": [ "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "ENSBTAT00000017725", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "Q2T9Q1", "ENSBTAT00000017725", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438" ] }, "reaction_10082026": { "compartment": "compartment_6791047", "id": "reaction_10082026", "reactome": "R-BTA-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082022", "species_10082020", "species_10076602" ], "products": [ "species_10082024" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061619", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "P41541", "ENSBTAT00000022642", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619" ] }, "reaction_10082045": { "compartment": "compartment_6791047", "id": "reaction_10082045", "reactome": "R-BTA-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082036", "species_113592" ], "products": [ "species_29370", "species_10082042" ], "modifiers": [ [ "species_10082036", "catalyst" ] ], "additional_components": [ "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10082038": { "compartment": "compartment_6791047", "id": "reaction_10082038", "reactome": "R-BTA-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082034", "species_10082024" ], "products": [ "species_10082036" ], "modifiers": [], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "P41541", "ENSBTAT00000022642", "A0A3Q1MWA3", "ENSBTAT00000083281", "species_29438", "E1BMC4", "ENSBTAT00000061619", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420" ] }, "reaction_10053337": { "compartment": "compartment_20699", "id": "reaction_10053337", "reactome": "R-BTA-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964831" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "CHEBI:60629", "CHEBI:60628", "CHEBI:60627", "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053339": { "compartment": "compartment_20699", "id": "reaction_10053339", "reactome": "R-BTA-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964828" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053317": { "compartment": "compartment_20699", "id": "reaction_10053317", "reactome": "R-BTA-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_915149" ], "products": [ "species_964752", "species_964740" ], "modifiers": [ [ "species_10053314", "catalyst" ] ], "additional_components": [ "E1BNG2", "ENSBTAT00000061143", "A0A3Q1MKX0", "ENSBTAT00000072527", "E1B7B0", "ENSBTAT00000061594" ] }, "reaction_10053324": { "compartment": "compartment_17963", "id": "reaction_10053324", "reactome": "R-BTA-964759", "name": "Alternative endo-mannosidase I route", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964754" ], "products": [ "species_964744", "species_964746" ], "modifiers": [ [ "species_10053321", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006614" ] }, "reaction_10053331": { "compartment": "compartment_20699", "id": "reaction_10053331", "reactome": "R-BTA-964768", "name": "Addition of GlcNAc to the glycan on the A arm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_964740" ], "products": [ "species_964837", "species_205687" ], "modifiers": [ [ "species_10053328", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066191" ] }, "reaction_10084373": { "compartment": "compartment_984", "id": "reaction_10084373", "reactome": "R-BTA-8855711", "name": "PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855720", "species_10084369" ], "products": [ "species_10084371" ], "modifiers": [], "additional_components": [ "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "Q32KM0", "ENSBTAT00000016010", "F1ME82", "ENSBTAT00000035098", "species_8855720" ] }, "reaction_10056058": { "compartment": "compartment_70101", "id": "reaction_10056058", "reactome": "R-BTA-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056054" ], "products": [ "species_10056056" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "CHEBI:60627", "CHEBI:60628", "species_915149", "CHEBI:60629", "species_964740", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10089391": { "compartment": "compartment_5460", "id": "reaction_10089391", "reactome": "R-BTA-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089384" ], "products": [], "modifiers": [ [ "species_10089388", "catalyst" ] ], "additional_components": [ "Q02372", "ENSBTAT00000000100", "ENSBTAT00000046212" ] }, "reaction_10056912": { "compartment": "compartment_24339", "id": "reaction_10056912", "reactome": "R-BTA-1236955", "name": "Movement of clathrin coated vesicles into early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056833" ], "products": [ "species_10056803" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056835": { "compartment": "compartment_24339", "id": "reaction_10056835", "reactome": "R-BTA-1236941", "name": "Internalization of receptor bound antigen into clathrin coted vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056819" ], "products": [ "species_10056833" ], "modifiers": [], "additional_components": [ "species_1236715", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10056805": { "compartment": "compartment_171043", "id": "reaction_10056805", "reactome": "R-BTA-1236940", "name": "Exogenous soluble antigen targeted to more stable early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056803" ], "products": [ "species_1236715", "species_10056801" ], "modifiers": [], "additional_components": [ "species_1236715", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333", "E1BB51", "ENSBTAT00000005993", "A0A3S5ZP99", "ENSBTAT00000011333" ] }, "reaction_10087823": { "compartment": "compartment_6791047", "id": "reaction_10087823", "reactome": "R-BTA-8951595", "name": "CALR, TAP, TAPBP dissociate from SEC22B:STX4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084863" ], "products": [ "species_10087813", "species_10087809", "species_10087821", "species_10087819" ], "modifiers": [], "additional_components": [ "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899", "A0A3Q1MMA1", "ENSBTAT00000066705", "A0A452DIB2", "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10084865": { "compartment": "compartment_6791047", "id": "reaction_10084865", "reactome": "R-BTA-8863858", "name": "SEC22B, CALR, STX4, TAP and TAPBP bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084853", "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "products": [ "species_10084863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787", "A0A3Q1MMA1", "ENSBTAT00000066705", "Q2NL04", "ENSBTAT00000022386", "A5D7J6", "ENSBTAT00000020111", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10084867": { "compartment": "compartment_6791047", "id": "reaction_10084867", "reactome": "R-BTA-8863914", "name": "Transport of SEC22B, TAP and PLC from ER to ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043539", "species_10055441", "species_10055470", "species_10055468" ], "products": [ "species_10084851", "species_10084861", "species_10076669", "species_10084859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066705", "F1MVY8", "ENSBTAT00000011787", "E1BJS0", "ENSBTAT00000080751", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000020111", "ENSBTAT00000022386", "ENSBTAT00000066705", "E1BJS0", "ENSBTAT00000080751", "F1MVY8", "ENSBTAT00000011787" ] }, "reaction_10056982": { "compartment": "compartment_1222693", "id": "reaction_10056982", "reactome": "R-BTA-1236965", "name": "Export of peptide loaded MHC class I complex to PM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056980" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056910": { "compartment": "compartment_171062", "id": "reaction_10056910", "reactome": "R-BTA-1236954", "name": "Trimming of peptides by IRAP in endocytic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236722" ], "products": [ "species_8943711", "species_1236727" ], "modifiers": [ [ "species_10056907", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10056914": { "compartment": "compartment_876", "id": "reaction_10056914", "reactome": "R-BTA-1236964", "name": "Translocation of peptide bound MHC class I complex to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056901" ], "products": [ "species_10042061" ], "modifiers": [], "additional_components": [ "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359" ] }, "reaction_10056903": { "compartment": "compartment_171043", "id": "reaction_10056903", "reactome": "R-BTA-1236943", "name": "Loading of antigen peptide onto MHC class I molecule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056899", "species_1236727" ], "products": [ "species_10056901" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "species_1236727", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878" ] }, "reaction_10057004": { "compartment": "compartment_263698", "id": "reaction_10057004", "reactome": "R-BTA-1236967", "name": "Alkalization of the phagosomal lumen by NOX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_2000347" ], "products": [ "species_2000345", "species_2000349", "species_2000348" ], "modifiers": [ [ "species_10057001", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657" ] }, "reaction_10041962": { "compartment": "compartment_876", "id": "reaction_10041962", "reactome": "R-BTA-198818", "name": "SLC2A1,3 transports DeHA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198852" ], "products": [ "species_198827" ], "modifiers": [ [ "species_10041959", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042889" ] }, "reaction_10041955": { "compartment": "compartment_70101", "id": "reaction_10041955", "reactome": "R-BTA-198813", "name": "GSTO dimers reduce DeHA to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_198827" ], "products": [ "species_198816", "species_111745" ], "modifiers": [ [ "species_10041952", "catalyst" ] ], "additional_components": [ "E1BED9", "ENSBTAT00000005211" ] }, "reaction_10041975": { "compartment": "compartment_876", "id": "reaction_10041975", "reactome": "R-BTA-198870", "name": "SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198836", "species_74113" ], "products": [ "species_83910", "species_198816" ], "modifiers": [ [ "species_10041972", "catalyst" ] ], "additional_components": [ "E1BI45", "ENSBTAT00000010823", "E1BP61", "ENSBTAT00000083275" ] }, "reaction_10083656": { "compartment": "compartment_70101", "id": "reaction_10083656", "reactome": "R-BTA-8848930", "name": "PTK6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083480" ], "products": [ "species_10083654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122" ] }, "reaction_10083672": { "compartment": "compartment_7660", "id": "reaction_10083672", "reactome": "R-BTA-8848975", "name": "PTK6 phosphorylates KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10083662" ], "products": [ "species_10083654", "species_113582", "species_10083669" ], "modifiers": [ [ "species_10083662", "catalyst" ] ], "additional_components": [ "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083676": { "compartment": "compartment_7660", "id": "reaction_10083676", "reactome": "R-BTA-8848993", "name": "Phosphorylated KHDRBS1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083669" ], "products": [ "species_10083674" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016581", "ENSBTAT00000016581" ] }, "reaction_10083664": { "compartment": "compartment_7660", "id": "reaction_10083664", "reactome": "R-BTA-8848939", "name": "PTK6 binds KHDRBS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083654", "species_10083660" ], "products": [ "species_10083662" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000016581", "Q29RQ2", "ENSBTAT00000016581", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10037748": { "compartment": "compartment_17957", "id": "reaction_10037748", "reactome": "R-BTA-140355", "name": "Arachidonic acid is oxidised to PGG2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10037751": { "compartment": "compartment_17957", "id": "reaction_10037751", "reactome": "R-BTA-140359", "name": "PGG2 is reduced to PGH2 by PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10037745", "catalyst" ] ], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10063448": { "compartment": "compartment_17957", "id": "reaction_10063448", "reactome": "R-BTA-2046095", "name": "Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046060", "species_113601" ], "products": [ "species_2046048", "species_113519", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063450": { "compartment": "compartment_12045", "id": "reaction_10063450", "reactome": "R-BTA-2046096", "name": "Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046063" ], "products": [ "species_194653", "species_113519", "species_2046042" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063452": { "compartment": "compartment_17957", "id": "reaction_10063452", "reactome": "R-BTA-2046097", "name": "Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046048", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046050" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063454": { "compartment": "compartment_12045", "id": "reaction_10063454", "reactome": "R-BTA-2046098", "name": "Activation of linoleic acid to linoleoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_162743", "species_2046044" ], "products": [ "species_2046064", "species_2046049", "species_2046063" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063442": { "compartment": "compartment_17957", "id": "reaction_10063442", "reactome": "R-BTA-2046092", "name": "Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046045" ], "products": [ "species_194653", "species_113519", "species_2046053" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063413": { "compartment": "compartment_12045", "id": "reaction_10063413", "reactome": "R-BTA-2046083", "name": "Elongation of arachidonyl-CoA to docosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046053", "species_113601" ], "products": [ "species_113519", "species_162743", "species_159751", "species_2046060" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063444": { "compartment": "compartment_12045", "id": "reaction_10063444", "reactome": "R-BTA-2046093", "name": "Translocation of tetracosapentaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046050", "species_211579" ], "products": [ "species_5228339", "species_2046055", "species_211606" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063446": { "compartment": "compartment_17957", "id": "reaction_10063446", "reactome": "R-BTA-2046094", "name": "Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046042", "species_113601" ], "products": [ "species_113519", "species_113564", "species_162743", "species_159751", "species_2046045" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063437": { "compartment": "compartment_17957", "id": "reaction_10063437", "reactome": "R-BTA-2046089", "name": "Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_2046051", "species_194697" ], "products": [ "species_194653", "species_113519", "species_2046059" ], "modifiers": [ [ "species_10063434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082100" ] }, "reaction_10063420": { "compartment": "compartment_12045", "id": "reaction_10063420", "reactome": "R-BTA-2046084", "name": "Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_194697", "species_2046062" ], "products": [ "species_194653", "species_113519", "species_2046052" ], "modifiers": [ [ "species_10063417", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020610" ] }, "reaction_10063425": { "compartment": "compartment_12045", "id": "reaction_10063425", "reactome": "R-BTA-2046085", "name": "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_211579", "species_2046056", "species_162743" ], "products": [ "species_2046064", "species_2046049", "species_2046062" ], "modifiers": [ [ "species_10063422", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LWT4", "ENSBTAT00000078831" ] }, "reaction_10063456": { "compartment": "compartment_12045", "id": "reaction_10063456", "reactome": "R-BTA-2046100", "name": "Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046059", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046057", "species_162743", "species_159751" ], "modifiers": [ [ "species_10063410", "catalyst" ] ], "additional_components": [ "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10063440": { "compartment": "compartment_17957", "id": "reaction_10063440", "reactome": "R-BTA-2046090", "name": "Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046057", "species_113601" ], "products": [ "species_113519", "species_2046065", "species_113564", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074314" ] }, "reaction_10063570": { "compartment": "compartment_17951", "id": "reaction_10063570", "reactome": "R-BTA-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_2066765" ], "products": [ "species_193514", "species_2066763" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10063573": { "compartment": "compartment_17951", "id": "reaction_10063573", "reactome": "R-BTA-2066788", "name": "Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_2066762" ], "products": [ "species_353123", "species_2066765" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10063428": { "compartment": "compartment_17957", "id": "reaction_10063428", "reactome": "R-BTA-2046087", "name": "Translocation of tetracosahexaenoyl-CoA to peroxisomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046054", "species_211579" ], "products": [ "species_426639", "species_211606", "species_2046047" ], "modifiers": [ [ "species_10046702", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027382" ] }, "reaction_10063430": { "compartment": "compartment_17957", "id": "reaction_10063430", "reactome": "R-BTA-2046088", "name": "Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2046066", "species_2046052", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2046051", "species_162743", "species_159751" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10033912": { "compartment": "compartment_5460", "id": "reaction_10033912", "reactome": "R-BTA-71031", "name": "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70843", "species_113593", "species_29376" ], "products": [ "species_113548", "species_113581", "species_71019" ], "modifiers": [ [ "species_10033909", "catalyst" ] ], "additional_components": [ "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10033896": { "compartment": "compartment_5460", "id": "reaction_10033896", "reactome": "R-BTA-71020", "name": "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71019" ], "products": [ "species_71009" ], "modifiers": [ [ "species_10033893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000049741" ] }, "reaction_10033889": { "compartment": "compartment_5460", "id": "reaction_10033889", "reactome": "R-BTA-71010", "name": "MUT isomerises L-MM-CoA to SUCC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71009" ], "products": [ "species_70958" ], "modifiers": [ [ "species_10033884", "catalyst" ] ], "additional_components": [ "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10075631": { "compartment": "compartment_5460", "id": "reaction_10075631", "reactome": "R-BTA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690540", "species_113521" ], "products": [ "species_29374", "species_5690519" ], "modifiers": [ [ "species_10075628", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_30495", "CHEBI:59554", "E1BA10", "ENSBTAP00000020594", "A6QQA9", "ENSBTAT00000074250", "F1N234", "ENSBTAT00000074250", "E1BAC0", "ENSBTAT00000000922" ] }, "reaction_10036029": { "compartment": "compartment_5460", "id": "reaction_10036029", "reactome": "R-BTA-77331", "name": "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77330" ], "products": [ "species_113529", "species_29362", "species_77328" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036038": { "compartment": "compartment_5460", "id": "reaction_10036038", "reactome": "R-BTA-77338", "name": "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77337" ], "products": [ "species_77332", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036027": { "compartment": "compartment_5460", "id": "reaction_10036027", "reactome": "R-BTA-77323", "name": "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77322", "species_113526" ], "products": [ "species_77320", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036040": { "compartment": "compartment_5460", "id": "reaction_10036040", "reactome": "R-BTA-77342", "name": "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77341", "species_113526" ], "products": [ "species_77339", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036042": { "compartment": "compartment_5460", "id": "reaction_10036042", "reactome": "R-BTA-77345", "name": "Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77308", "species_113596" ], "products": [ "species_77343", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10036012": { "compartment": "compartment_5460", "id": "reaction_10036012", "reactome": "R-BTA-77254", "name": "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77252" ], "products": [ "species_113529", "species_77253", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036021": { "compartment": "compartment_5460", "id": "reaction_10036021", "reactome": "R-BTA-77263", "name": "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77261" ], "products": [ "species_77255", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10036025": { "compartment": "compartment_5460", "id": "reaction_10036025", "reactome": "R-BTA-77312", "name": "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_77251" ], "products": [ "species_73871", "species_113529", "species_29362" ], "modifiers": [ [ "species_10036009", "catalyst" ] ], "additional_components": [ "A0A3Q1LS03", "ENSBTAT00000054475" ] }, "reaction_10036023": { "compartment": "compartment_5460", "id": "reaction_10036023", "reactome": "R-BTA-77274", "name": "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_77272" ], "products": [ "species_77273", "species_31649" ], "modifiers": [ [ "species_10036018", "catalyst" ] ], "additional_components": [ "Q08D92", "ENSBTAT00000013988" ] }, "reaction_10086403": { "compartment": "compartment_70616", "id": "reaction_10086403", "reactome": "R-BTA-8933547", "name": "MCAT transfers Mal from Mal-CoA to NDUFAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977314", "species_10086393" ], "products": [ "species_29374", "species_10086396" ], "modifiers": [ [ "species_10086400", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008382", "ENSBTAT00000008382", "ENSBTAT00000003130" ] }, "reaction_10036664": { "compartment": "compartment_5460", "id": "reaction_10036664", "reactome": "R-BTA-109998", "name": "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109994" ], "products": [ "species_77343" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036218": { "compartment": "compartment_5460", "id": "reaction_10036218", "reactome": "R-BTA-109338", "name": "Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77358" ], "products": [ "species_77360" ], "modifiers": [ [ "species_10036215", "catalyst" ] ], "additional_components": [ "F1MTT7", "ENSBTAT00000013144" ] }, "reaction_10036220": { "compartment": "compartment_5460", "id": "reaction_10036220", "reactome": "R-BTA-109341", "name": "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_109986" ], "products": [ "species_109990", "species_31649" ], "modifiers": [ [ "species_10036035", "catalyst" ] ], "additional_components": [ "Q3SZB4", "ENSBTAT00000033470" ] }, "reaction_10075607": { "compartment": "compartment_70101", "id": "reaction_10075607", "reactome": "R-BTA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5690044" ], "products": [ "species_5690064", "species_76194" ], "modifiers": [ [ "species_10075600", "catalyst" ], [ "species_10075605", "catalyst" ] ], "additional_components": [ "CHEBI:61907", "CHEBI:33184", "CHEBI:59554", "species_30495", "F6QGE6", "ENSBTAT00000021731", "A6QQA9", "ENSBTAT00000074250", "A0A3Q1MI69", "ENSBTAT00000075163", "E1BNW7", "ENSBTAT00000014753", "ENSBTAT00000024898" ] }, "reaction_10076806": { "compartment": "compartment_5460", "id": "reaction_10076806", "reactome": "R-BTA-5695980", "name": "ACAD10 dehydrogenates S-2MPDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_5695946" ], "products": [ "species_5695949", "species_31649" ], "modifiers": [ [ "species_10076803", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080862" ] }, "reaction_10042860": { "compartment": "compartment_70101", "id": "reaction_10042860", "reactome": "R-BTA-200406", "name": "CPT1A,B transfers PALM to CAR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549207", "species_200993" ], "products": [ "species_201034", "species_76194" ], "modifiers": [ [ "species_10042857", "catalyst" ], [ "species_29508", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMV3", "ENSBTAT00000069870", "Q58DK1", "ENSBTAT00000021357" ] }, "reaction_10042897": { "compartment": "compartment_17927", "id": "reaction_10042897", "reactome": "R-BTA-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10042894", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000217" ] }, "reaction_10085185": { "compartment": "compartment_70101", "id": "reaction_10085185", "reactome": "R-BTA-8866941", "name": "MID1IP1 binds THRSP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085181", "species_10085177" ], "products": [ "species_10085183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015490", "ENSBTAT00000015231", "Q08E46", "ENSBTAT00000015231", "A0A3S5ZPK2", "ENSBTAT00000015490" ] }, "reaction_10077001": { "compartment": "compartment_12045", "id": "reaction_10077001", "reactome": "R-BTA-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192172", "species_5696426" ], "products": [ "species_5696412", "species_162743" ], "modifiers": [ [ "species_10076998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025081" ] }, "reaction_10044657": { "compartment": "compartment_876", "id": "reaction_10044657", "reactome": "R-BTA-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266013" ], "products": [ "species_266074", "species_210382" ], "modifiers": [ [ "species_10044654", "catalyst" ] ], "additional_components": [ "F1MYJ3", "ENSBTAT00000023658", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10064482": { "compartment": "compartment_12045", "id": "reaction_10064482", "reactome": "R-BTA-2161745", "name": "20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2161636" ], "products": [ "species_29356", "species_29366", "species_2142740" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064581": { "compartment": "compartment_70101", "id": "reaction_10064581", "reactome": "R-BTA-2162019", "name": "LTA4 is converted to EXA4 by ALOX15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281" ], "products": [ "species_2142772" ], "modifiers": [ [ "species_10064560", "catalyst" ] ], "additional_components": [ "P27479", "ENSBTAT00000015911", "species_71067" ] }, "reaction_10064503": { "compartment": "compartment_12045", "id": "reaction_10064503", "reactome": "R-BTA-2161792", "name": "20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_2142740" ], "products": [ "species_2161582", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044148", "catalyst" ] ], "additional_components": [ "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364" ] }, "reaction_10064578": { "compartment": "compartment_70101", "id": "reaction_10064578", "reactome": "R-BTA-2162002", "name": "Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142718" ], "modifiers": [ [ "species_10064575", "catalyst" ] ], "additional_components": [ "F1MXW0", "ENSBTAT00000011570", "species_71067", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064546": { "compartment": "compartment_12045", "id": "reaction_10064546", "reactome": "R-BTA-2161951", "name": "Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142738" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064554": { "compartment": "compartment_70101", "id": "reaction_10064554", "reactome": "R-BTA-2161959", "name": "12R-HpETE is reduced to 12R-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_2142790" ], "products": [ "species_29356", "species_2142716", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064565": { "compartment": "compartment_70101", "id": "reaction_10064565", "reactome": "R-BTA-2161964", "name": "Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2142811" ], "modifiers": [ [ "species_10064562", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240", "P27479", "ENSBTAT00000015911" ] }, "reaction_10064567": { "compartment": "compartment_70101", "id": "reaction_10064567", "reactome": "R-BTA-2161999", "name": "12S-HpETE is reduced to 12S-HETE by GPX1/2/4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142811", "species_29450" ], "products": [ "species_29356", "species_2142678", "species_111745" ], "modifiers": [ [ "species_10064551", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10064534": { "compartment": "compartment_70101", "id": "reaction_10064534", "reactome": "R-BTA-2161948", "name": "Arachidonic acid is converted to 12-oxoETE by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29768" ], "products": [ "species_2142745" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10076382": { "compartment": "compartment_12045", "id": "reaction_10076382", "reactome": "R-BTA-5693742", "name": "FAAH hydrolyses AEA to AA and ETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693754" ], "products": [ "species_1498751", "species_29768" ], "modifiers": [ [ "species_10076379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071864" ] }, "reaction_10064506": { "compartment": "compartment_70101", "id": "reaction_10064506", "reactome": "R-BTA-2161794", "name": "Arachidonic acid is converted to HXA3/B3 by ALOX12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29768" ], "products": [ "species_2162031" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:36190", "CHEBI:34784", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10086336": { "compartment": "compartment_984", "id": "reaction_10086336", "reactome": "R-BTA-8932633", "name": "PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8932801" ], "products": [ "species_8932804" ], "modifiers": [ [ "species_10086333", "catalyst" ] ], "additional_components": [ "Q1JQD3", "ENSBTAT00000049076", "species_74016", "Q2KIW1", "ENSBTAT00000020790" ] }, "reaction_10064521": { "compartment": "compartment_12045", "id": "reaction_10064521", "reactome": "R-BTA-2161890", "name": "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_29366", "species_2142739" ], "modifiers": [ [ "species_10064518", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10064526": { "compartment": "compartment_12045", "id": "reaction_10064526", "reactome": "R-BTA-2161899", "name": "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29768", "species_29364" ], "products": [ "species_29356", "species_2161753", "species_29366" ], "modifiers": [ [ "species_10064523", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34490", "CHEBI:34157", "A0A3S5ZP79", "ENSBTAT00000027159", "F1MM10", "ENSBTAT00000061300", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10065210": { "compartment": "compartment_17957", "id": "reaction_10065210", "reactome": "R-BTA-2309773", "name": "PGG2 is reduced to PGH2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_76342", "species_140357" ], "products": [ "species_113519", "species_30138" ], "modifiers": [ [ "species_10065205", "catalyst" ], [ "species_549282", "catalyst" ], [ "species_10065208", "inhibitor" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064442": { "compartment": "compartment_70101", "id": "reaction_10064442", "reactome": "R-BTA-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_265283", "species_29364" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064474": { "compartment": "compartment_12045", "id": "reaction_10064474", "reactome": "R-BTA-2161660", "name": "PGH2 is isomerised to PGE2 by PTGES", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10064471", "catalyst" ] ], "additional_components": [ "species_29450", "Q95L14", "ENSBTAT00000025912" ] }, "reaction_10065213": { "compartment": "compartment_70101", "id": "reaction_10065213", "reactome": "R-BTA-2309779", "name": "PTGS2 dimer binds PTGS2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9716714", "species_10065205" ], "products": [ "species_10065208" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064445": { "compartment": "compartment_70101", "id": "reaction_10064445", "reactome": "R-BTA-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10064479": { "compartment": "compartment_70101", "id": "reaction_10064479", "reactome": "R-BTA-2161701", "name": "PGH2 is isomerised to PGD2 by HPGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_879629" ], "modifiers": [ [ "species_10064476", "catalyst" ] ], "additional_components": [ "species_29450", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10064465": { "compartment": "compartment_70101", "id": "reaction_10064465", "reactome": "R-BTA-2161651", "name": "PGE2 is converted to PGF2a by CBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265287" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10064462", "catalyst" ] ], "additional_components": [ "A0A3Q1NG39", "ENSBTAT00000084736", "Q3T0T9", "ENSBTAT00000043292" ] }, "reaction_10044599": { "compartment": "compartment_70101", "id": "reaction_10044599", "reactome": "R-BTA-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10044596", "catalyst" ] ], "additional_components": [ "A0A3Q1LFK5", "ENSBTAT00000071669", "A0A452DIU3", "ENSBTAT00000023908" ] }, "reaction_10065225": { "compartment": "compartment_70101", "id": "reaction_10065225", "reactome": "R-BTA-2314686", "name": "Aspirin acetylates PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065205", "species_2314693" ], "products": [ "species_10064543", "species_2314690" ], "modifiers": [], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10065216": { "compartment": "compartment_17957", "id": "reaction_10065216", "reactome": "R-BTA-2309787", "name": "Arachidonic acid is oxidised to PGG2 by PTGS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_140356" ], "products": [ "species_140357" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10064452": { "compartment": "compartment_12045", "id": "reaction_10064452", "reactome": "R-BTA-2161620", "name": "PGH2 is isomerised to PGD2 by PTGDS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30138" ], "products": [ "species_2161634" ], "modifiers": [ [ "species_10064449", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020065" ] }, "reaction_10065223": { "compartment": "compartment_70101", "id": "reaction_10065223", "reactome": "R-BTA-2314678", "name": "Aspirin acetylates PTGS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037745", "species_2314693" ], "products": [ "species_10065221", "species_2314690" ], "modifiers": [], "additional_components": [ "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355", "A0A452DI94", "ENSBTAT00000008833", "CHEBI:26355" ] }, "reaction_10064511": { "compartment": "compartment_12045", "id": "reaction_10064511", "reactome": "R-BTA-2161795", "name": "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2161639" ], "modifiers": [ [ "species_10064508", "catalyst" ] ], "additional_components": [ "CHEBI:63995", "CHEBI:63994", "CHEBI:63579", "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064531": { "compartment": "compartment_12045", "id": "reaction_10064531", "reactome": "R-BTA-2161940", "name": "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142780" ], "modifiers": [ [ "species_10064528", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785", "M0QW30", "ENSBTAT00000072981", "A0A3Q1MCJ2", "ENSBTAT00000073532", "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10064516": { "compartment": "compartment_12045", "id": "reaction_10064516", "reactome": "R-BTA-2161814", "name": "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_2142836" ], "modifiers": [ [ "species_10064513", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1N3I8", "ENSBTAT00000021785", "F1MM10", "ENSBTAT00000061300", "F1MFI9", "ENSBTAT00000017246", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "F1MNG1", "ENSBTAT00000075887" ] }, "reaction_10047033": { "compartment": "compartment_17951", "id": "reaction_10047033", "reactome": "R-BTA-389889", "name": "ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047030", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1LWZ7", "ENSBTAT00000082299", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10047056": { "compartment": "compartment_17951", "id": "reaction_10047056", "reactome": "R-BTA-390304", "name": "acetyl-CoA + H2O => acetate + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_353123" ], "products": [ "species_193514", "species_390305" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10047042": { "compartment": "compartment_17951", "id": "reaction_10047042", "reactome": "R-BTA-389891", "name": "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389893" ], "products": [ "species_113575", "species_389894" ], "modifiers": [ [ "species_10047039", "catalyst" ] ], "additional_components": [ "A4IFA4", "ENSBTAT00000044120", "species_113596" ] }, "reaction_10047044": { "compartment": "compartment_17951", "id": "reaction_10047044", "reactome": "R-BTA-389897", "name": "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389569" ], "products": [ "species_389893" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10077835": { "compartment": "compartment_17951", "id": "reaction_10077835", "reactome": "R-BTA-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_6787810" ], "products": [ "species_113575", "species_6787814" ], "modifiers": [ [ "species_10077832", "catalyst" ] ], "additional_components": [ "Q3ZBW2", "ENSBTAT00000000134" ] }, "reaction_10077784": { "compartment": "compartment_17951", "id": "reaction_10077784", "reactome": "R-BTA-6786720", "name": "DECR2 reduces LCtE-CoA to t3enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6786723", "species_113602" ], "products": [ "species_6786715", "species_389556" ], "modifiers": [ [ "species_10077781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072961" ] }, "reaction_10075576": { "compartment": "compartment_17951", "id": "reaction_10075576", "reactome": "R-BTA-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690520", "species_141343" ], "products": [ "species_5690539", "species_193514" ], "modifiers": [ [ "species_10075573", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "CHEBI:59554", "species_30495", "A0A3Q1N6L4", "ENSBTAT00000074004", "A0A3S5ZPS3", "ENSBTAT00000003683", "E1BBG0", "ENSBTAT00000013568" ] }, "reaction_10047053": { "compartment": "compartment_17951", "id": "reaction_10047053", "reactome": "R-BTA-390250", "name": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193514", "species_390241" ], "products": [ "species_353123", "species_390246" ], "modifiers": [ [ "species_10047050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024335" ] }, "reaction_10082880": { "compartment": "compartment_17951", "id": "reaction_10082880", "reactome": "R-BTA-6809808", "name": "ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809801" ], "products": [ "species_6809800" ], "modifiers": [ [ "species_10082877", "catalyst" ] ], "additional_components": [ "A0A3Q1LP28", "ENSBTAT00000083505" ] }, "reaction_10054592": { "compartment": "compartment_17951", "id": "reaction_10054592", "reactome": "R-BTA-977317", "name": "malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977323" ], "products": [ "species_353123", "species_389536" ], "modifiers": [ [ "species_10054589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005562" ] }, "reaction_10047058": { "compartment": "compartment_17947", "id": "reaction_10047058", "reactome": "R-BTA-390393", "name": "Peroxisomal uptake of very long-chain fatty acyl CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390394" ], "products": [ "species_390260" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10082889": { "compartment": "compartment_17947", "id": "reaction_10082889", "reactome": "R-BTA-6809810", "name": "PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_6809811", "species_113602" ], "products": [ "species_389615", "species_389556" ], "modifiers": [ [ "species_10082886", "catalyst" ] ], "additional_components": [ "G3X6L7", "ENSBTAT00000008962" ] }, "reaction_10047001": { "compartment": "compartment_17951", "id": "reaction_10047001", "reactome": "R-BTA-389639", "name": "phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389615", "species_389537" ], "products": [ "species_389594", "species_389583", "species_389536" ], "modifiers": [ [ "species_10046998", "catalyst" ] ], "additional_components": [ "species_71067", "O18778", "ENSBTAT00000010126" ] }, "reaction_10046984": { "compartment": "compartment_17951", "id": "reaction_10046984", "reactome": "R-BTA-389609", "name": "ALDH3A2-2 oxidizes pristanal to pristanate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389636", "species_192307" ], "products": [ "species_193465", "species_6811612", "species_192305" ], "modifiers": [ [ "species_10046981", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10046989": { "compartment": "compartment_17951", "id": "reaction_10046989", "reactome": "R-BTA-389622", "name": "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389596", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389615", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10046992": { "compartment": "compartment_17951", "id": "reaction_10046992", "reactome": "R-BTA-389632", "name": "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6811612", "species_193514", "species_389573" ], "products": [ "species_389593", "species_389569", "species_389620" ], "modifiers": [ [ "species_10046986", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10083389": { "compartment": "compartment_12045", "id": "reaction_10083389", "reactome": "R-BTA-8847579", "name": "SCD5 desaturates ST-CoA to OLE-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_70106", "species_4085415", "species_29368" ], "products": [ "species_4085425", "species_29356", "species_5690558" ], "modifiers": [ [ "species_10083386", "catalyst" ] ], "additional_components": [ "Q2KIA4", "ENSBTAT00000025820" ] }, "reaction_10051261": { "compartment": "compartment_70101", "id": "reaction_10051261", "reactome": "R-BTA-548814", "name": "ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29508", "species_200993" ], "products": [ "species_113528", "species_548812", "species_76194" ], "modifiers": [ [ "species_10051258", "catalyst" ] ], "additional_components": [ "A6QNQ7", "ENSBTAT00000067475", "E1BBR7", "ENSBTAT00000020842" ] }, "reaction_10042961": { "compartment": "compartment_70101", "id": "reaction_10042961", "reactome": "R-BTA-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_111294", "species_29356", "species_200993", "species_76577" ], "modifiers": [ [ "species_10042958", "catalyst" ] ], "additional_components": [ "Q1LZF6", "ENSBTAT00000064114", "A0A3Q1LPX2", "ENSBTAT00000080693", "A0A3Q1LWT4", "ENSBTAT00000078831", "F1MEX9", "ENSBTAT00000022939" ] }, "reaction_10074353": { "compartment": "compartment_12045", "id": "reaction_10074353", "reactome": "R-BTA-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_29356", "species_5676634" ], "modifiers": [ [ "species_10074350", "catalyst" ] ], "additional_components": [ "F1MXJ1", "ENSBTAT00000046976" ] }, "reaction_10051252": { "compartment": "compartment_70101", "id": "reaction_10051252", "reactome": "R-BTA-548800", "name": "ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_548819", "species_29508" ], "products": [ "species_113528", "species_548816", "species_76194" ], "modifiers": [ [ "species_10051249", "catalyst" ] ], "additional_components": [ "E1BBR7", "ENSBTAT00000020842", "Q2KJD9", "ENSBTAT00000004358", "A4FUF2", "ENSBTAT00000074314" ] }, "reaction_10044985": { "compartment": "compartment_876", "id": "reaction_10044985", "reactome": "R-BTA-352174", "name": "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352186", "species_70106", "species_74113" ], "products": [ "species_351626", "species_352169", "species_83910" ], "modifiers": [ [ "species_10044982", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_29612", "species_29642", "species_29472", "species_352036", "species_29642", "species_29612", "ENSBTAT00000011214" ] }, "reaction_10044955": { "compartment": "compartment_876", "id": "reaction_10044955", "reactome": "R-BTA-352103", "name": "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044952", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000072259" ] }, "reaction_10045501": { "compartment": "compartment_876", "id": "reaction_10045501", "reactome": "R-BTA-375776", "name": "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045498", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000019060" ] }, "reaction_10044978": { "compartment": "compartment_876", "id": "reaction_10044978", "reactome": "R-BTA-352158", "name": "SLC16A10-mediated uptake of aromatic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352161" ], "products": [ "species_352139" ], "modifiers": [ [ "species_10044975", "catalyst" ] ], "additional_components": [ "species_352006", "species_352030", "species_351993", "species_352030", "species_352006", "species_351993", "ENSBTAT00000012176" ] }, "reaction_10044948": { "compartment": "compartment_876", "id": "reaction_10044948", "reactome": "R-BTA-352059", "name": "SLC6A15-mediated amino acid uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352051", "species_74113" ], "products": [ "species_83910", "species_352048" ], "modifiers": [ [ "species_10044945", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "CHEBI:58045", "species_379717", "species_351990", "species_111707", "species_379732", "species_29642", "CHEBI:57427", "species_174390", "CHEBI:18240", "species_29702", "species_29472", "species_379717", "species_351990", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:18240", "CHEBI:58045", "species_29702", "species_352036", "species_29642", "species_111707", "ENSBTAT00000076418" ] }, "reaction_10045494": { "compartment": "compartment_876", "id": "reaction_10045494", "reactome": "R-BTA-375770", "name": "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375765" ], "products": [ "species_375781" ], "modifiers": [ [ "species_10045491", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000009736" ] }, "reaction_10088905": { "compartment": "compartment_70101", "id": "reaction_10088905", "reactome": "R-BTA-8959781", "name": "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8959777" ], "products": [ "species_8959775" ], "modifiers": [ [ "species_10088902", "catalyst" ] ], "additional_components": [ "CHEBI:28229", "species_113586", "species_113530", "species_29612", "CHEBI:32551", "CHEBI:27747", "species_113586", "CHEBI:32551", "species_113530", "species_29612", "CHEBI:28229", "CHEBI:27747", "ENSBTAT00000018163" ] }, "reaction_10085384": { "compartment": "compartment_876", "id": "reaction_10085384", "reactome": "R-BTA-8870354", "name": "SLC36A4 transports extracellular L-Pro to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352033" ], "products": [ "species_113538" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10045480": { "compartment": "compartment_876", "id": "reaction_10045480", "reactome": "R-BTA-375473", "name": "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_375458", "species_74113" ], "products": [ "species_375481", "species_83910" ], "modifiers": [ [ "species_10045477", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "species_29472", "CHEBI:58045", "species_111707", "species_379732", "species_29424", "CHEBI:57427", "species_174390", "species_352030", "species_351993", "species_29702", "species_29424", "species_29472", "species_352030", "species_379732", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_352036", "species_111707", "species_352006", "species_351993", "ENSBTAT00000064818" ] }, "reaction_10044971": { "compartment": "compartment_876", "id": "reaction_10044971", "reactome": "R-BTA-352136", "name": "SLC38A4 (ATA3)-mediated uptake of arginine and lysine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352128" ], "products": [ "species_352135" ], "modifiers": [ [ "species_10044968", "catalyst" ] ], "additional_components": [ "CHEBI:32551", "species_113530", "species_113530", "CHEBI:32551", "ENSBTAT00000070473" ] }, "reaction_10044941": { "compartment": "compartment_876", "id": "reaction_10044941", "reactome": "R-BTA-352029", "name": "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352007", "species_74113" ], "products": [ "species_351982", "species_83910", "species_352022" ], "modifiers": [ [ "species_10044938", "catalyst" ] ], "additional_components": [ "species_73590", "species_428571", "species_352015", "CHEBI:48950", "CHEBI:48950", "species_73590", "species_352015", "species_428571", "ENSBTAT00000067153" ] }, "reaction_10045487": { "compartment": "compartment_876", "id": "reaction_10045487", "reactome": "R-BTA-375487", "name": "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_375468", "species_74113" ], "products": [ "species_83910", "species_375459", "species_352022" ], "modifiers": [ [ "species_10045484", "catalyst" ] ], "additional_components": [ "species_352036", "species_352006", "CHEBI:58045", "species_29612", "species_379732", "species_29424", "species_113530", "species_73590", "CHEBI:32551", "species_111707", "CHEBI:57427", "species_174390", "species_29702", "species_379732", "species_29702", "species_29612", "CHEBI:32551", "species_29424", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_73590", "species_352036", "species_111707", "species_113530", "species_352006", "ENSBTAT00000083685" ] }, "reaction_10045473": { "compartment": "compartment_876", "id": "reaction_10045473", "reactome": "R-BTA-375405", "name": "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_375409" ], "products": [ "species_70106", "species_375414" ], "modifiers": [ [ "species_10045470", "catalyst" ] ], "additional_components": [ "species_379717", "species_29424", "species_29424", "species_379717", "ENSBTAT00000027731" ] }, "reaction_10044962": { "compartment": "compartment_876", "id": "reaction_10044962", "reactome": "R-BTA-352107", "name": "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352101" ], "products": [ "species_352114" ], "modifiers": [ [ "species_10044959", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "species_174390", "species_351993", "species_29702", "CHEBI:57427", "species_174390", "CHEBI:58045", "species_29702", "species_351993", "ENSBTAT00000015260" ] }, "reaction_10044964": { "compartment": "compartment_876", "id": "reaction_10044964", "reactome": "R-BTA-352108", "name": "SLC38A2 (ATA2)-mediated uptake of neutral amino acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352091", "species_74113" ], "products": [ "species_352088", "species_83910" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "species_352036", "species_29472", "species_379717", "species_351990", "species_379732", "species_29642", "species_29424", "CHEBI:57427", "species_174390", "species_29472", "species_29424", "species_379717", "species_379732", "species_351990", "CHEBI:57427", "species_174390", "species_352036", "species_29642", "ENSBTAT00000014749" ] }, "reaction_10044934": { "compartment": "compartment_876", "id": "reaction_10044934", "reactome": "R-BTA-351963", "name": "SLC6A18 transports Gly from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266029" ], "products": [ "species_29424" ], "modifiers": [ [ "species_10044931", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016676" ] }, "reaction_10039272": { "compartment": "compartment_984", "id": "reaction_10039272", "reactome": "R-BTA-166542", "name": "beta-NGF dimer binds to TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039264", "species_10039258" ], "products": [ "species_10039266" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10040684": { "compartment": "compartment_876", "id": "reaction_10040684", "reactome": "R-BTA-190065", "name": "Activated TrkA receptor internalizes to endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039569" ], "products": [ "species_10039684" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039270": { "compartment": "compartment_876", "id": "reaction_10039270", "reactome": "R-BTA-166538", "name": "The bound receptor dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039266", "species_10039258" ], "products": [ "species_10039268" ], "modifiers": [], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000067057", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10088473": { "compartment": "compartment_17957", "id": "reaction_10088473", "reactome": "R-BTA-8952289", "name": "FAM20C phosphorylates FAM20C substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088246", "species_8931885" ], "products": [ "species_10088464", "species_8931884" ], "modifiers": [ [ "species_10088246", "catalyst" ], [ "species_10088471", "catalyst" ] ], "additional_components": [ "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MI67", "ENSBTAT00000025557", "A0A3Q1NJR8", "ENSBTAT00000071014", "Q2KJH1", "ENSBTAT00000004992", "A0A5H1ZRH6", "ENSBTAT00000028238", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3X6N3", "ENSBTAT00000009564", "E1B8P3", "ENSBTAT00000002384", "P11116", "ENSBTAT00000020080", "F1MD77", "ENSBTAT00000015881", "P81644", "ENSBTAT00000012138", "A0A3Q1LEU1", "ENSBTAT00000081148", "E1BDK6", "ENSBTAT00000057452", "E1BG25", "ENSBTAT00000046533", "F1MD94", "ENSBTAT00000027836", "A4FUZ9", "ENSBTAT00000026336", "A0A452DII7", "ENSBTAT00000016252", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1MS36", "ENSBTAT00000076629", "Q95M18", "ENSBTAT00000004364", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "A0A3Q1MY30", "ENSBTAT00000082437", "E1BJF8", "ENSBTAT00000022706", "P02817", "ENSBTAT00000016034", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A140T8C8", "ENSBTAT00000053071", "P12763", "ENSBTAT00000000673", "F1MEA1", "ENSBTAT00000024433", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "F1MY12", "ENSBTAT00000016092", "F6RJ01", "ENSBTAT00000027753", "A0A3Q1LRR3", "ENSBTAT00000074422", "G3N348", "ENSBTAT00000082028", "P01035", "ENSBTAT00000000790", "A0A3Q1LMK4", "ENSBTAT00000076179", "A0A452DJ03", "ENSBTAT00000028372", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "E1BLA8", "ENSBTAT00000044756", "F1N0I3", "ENSBTAT00000023573", "A0A3Q1LIS3", "ENSBTAT00000085388", "Q27967", "ENSBTAT00000002631", "A0A3Q1N9Y5", "ENSBTAT00000085713", "G3X724", "ENSBTAT00000065790", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QPR4", "ENSBTAT00000044682", "A6QQR3", "ENSBTAT00000044682", "A0A3Q1MEX5", "ENSBTAT00000072231", "A0A3Q1NAS1", "ENSBTAT00000074235", "E1BHJ7", "ENSBTAT00000016190", "F6QSG5", "ENSBTAT00000056456", "A0A3Q1NIX0", "ENSBTAT00000078756", "A6QP86", "ENSBTAT00000054074", "G3N2W6", "ENSBTAT00000065790", "G3N2L2", "ENSBTAT00000063521", "Q6PX77", "ENSBTAT00000064918", "P34955", "ENSBTAT00000072441", "P01211", "ENSBTAT00000087134", "Q1LZE9", "ENSBTAT00000020194", "A0A3Q1N5X6", "ENSBTAT00000080120", "P11116", "ENSBTAT00000020080", "A0A3Q1LEU1", "ENSBTAT00000081148", "A6QP39", "ENSBTAT00000000202", "E1BG36", "ENSBTAT00000009958", "E1BG25", "ENSBTAT00000046533", "A4FUZ9", "ENSBTAT00000026336", "A0A3Q1MS36", "ENSBTAT00000076629", "A0A452DII7", "ENSBTAT00000016252", "F1N5H2", "ENSBTAT00000002297", "E1BJU2", "ENSBTAT00000008940", "F1MKR5", "ENSBTAT00000013661", "A0A3Q1N3Y2", "ENSBTAT00000073105", "Q3ZBZ6", "ENSBTAT00000027192", "E1BLA8", "ENSBTAT00000044756", "Q05717", "ENSBTAT00000078855", "P20959", "ENSBTAT00000053426", "P24591", "ENSBTAT00000064194", "A0A140T8C8", "ENSBTAT00000053071", "Q95M18", "ENSBTAT00000004364", "P26892", "ENSBTAT00000019865", "F1MPP2", "ENSBTAT00000025803", "F1MY12", "ENSBTAT00000016092", "F1MI67", "ENSBTAT00000025557", "F6RJ01", "ENSBTAT00000027753", "Q2KJH1", "ENSBTAT00000004992", "G3X6N3", "ENSBTAT00000009564", "Q6PX77", "ENSBTAT00000064918", "E1B8P3", "ENSBTAT00000002384", "A0A452DJ03", "ENSBTAT00000028372", "A0A5H1ZRH6", "ENSBTAT00000028238", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MEA1", "ENSBTAT00000024433", "A0A3Q1LMK4", "ENSBTAT00000076179", "G3N348", "ENSBTAT00000082028", "F1ME65", "ENSBTAT00000015804", "F1MAZ4", "ENSBTAT00000005810", "A0A3Q1LRR3", "ENSBTAT00000074422", "P01035", "ENSBTAT00000000790", "F6QH94", "ENSBTAT00000002508", "A0A452DHZ5", "ENSBTAT00000003073", "A0A3Q1N9Y5", "ENSBTAT00000085713", "Q1LZE9", "ENSBTAT00000020194", "F1N0I3", "ENSBTAT00000023573", "P01211", "ENSBTAT00000087134", "A0A3Q1NJR8", "ENSBTAT00000071014", "P34955", "ENSBTAT00000072441", "G3N2L2", "ENSBTAT00000063521", "A0A3Q1MEX5", "ENSBTAT00000072231", "A6QPR4", "ENSBTAT00000044682", "G3N2W6", "ENSBTAT00000065790", "A0A3Q1NAS1", "ENSBTAT00000074235", "A6QQR3", "ENSBTAT00000044682", "G3X724", "ENSBTAT00000065790", "A0A3Q1NIX0", "ENSBTAT00000078756", "E1BHJ7", "ENSBTAT00000016190", "A0A3Q1MB94", "ENSBTAT00000069263", "A6QP86", "ENSBTAT00000054074", "F6QSG5", "ENSBTAT00000056456", "Q27967", "ENSBTAT00000002631", "A0A3Q1LIS3", "ENSBTAT00000085388", "P81644", "ENSBTAT00000012138", "F1MD94", "ENSBTAT00000027836", "P12763", "ENSBTAT00000000673", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1MY30", "ENSBTAT00000082437", "P02817", "ENSBTAT00000016034", "E1BDK6", "ENSBTAT00000057452", "E1BJF8", "ENSBTAT00000022706", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N5X6", "ENSBTAT00000080120", "F1MJW4", "ENSBTAT00000001439" ] }, "reaction_10046621": { "compartment": "compartment_984", "id": "reaction_10046621", "reactome": "R-BTA-381487", "name": "IGFBP1 binds IGF forming IGF:IGFBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046613", "species_10046617" ], "products": [ "species_10046619" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014713", "ENSBTAT00000064194", "P24591", "ENSBTAT00000064194", "P07455", "ENSBTAT00000014713" ] }, "reaction_10068959": { "compartment": "compartment_7660", "id": "reaction_10068959", "reactome": "R-BTA-3878123", "name": "Initiation of SAHF formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068951", "species_10068947", "species_10068943", "species_10068955" ], "products": [ "species_10068957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064363", "ENSBTAT00000074434", "ENSBTAT00000002664", "ENSBTAT00000018360", "G3X746", "ENSBTAT00000018360", "Q2KIG1", "ENSBTAT00000002664", "A0A3Q1NMK6", "ENSBTAT00000074434", "G3N0Y4", "ENSBTAT00000064363" ] }, "reaction_10061480": { "compartment": "compartment_876", "id": "reaction_10061480", "reactome": "R-BTA-1963582", "name": "Trans-autophosphorylation of ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10057121" ], "modifiers": [ [ "species_10061477", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10061469": { "compartment": "compartment_876", "id": "reaction_10061469", "reactome": "R-BTA-1963581", "name": "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10061466" ], "products": [ "species_29370", "species_10057130" ], "modifiers": [ [ "species_10061466", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10057692": { "compartment": "compartment_70101", "id": "reaction_10057692", "reactome": "R-BTA-1306969", "name": "GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10057688" ], "products": [ "species_10057690" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10057695": { "compartment": "compartment_876", "id": "reaction_10057695", "reactome": "R-BTA-1306972", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10057690", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10086415": { "compartment": "compartment_70101", "id": "reaction_10086415", "reactome": "R-BTA-8934465", "name": "SHC1 binds PTPN12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084846", "species_10086408" ], "products": [ "species_10086413" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068950", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1M0B4", "ENSBTAT00000068950" ] }, "reaction_10057139": { "compartment": "compartment_876", "id": "reaction_10057139", "reactome": "R-BTA-1250195", "name": "SHC1 phosphorylation by ERBB2 heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057134" ], "products": [ "species_29370", "species_10057136" ], "modifiers": [ [ "species_10057134", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10083483": { "compartment": "compartment_70101", "id": "reaction_10083483", "reactome": "R-BTA-8848005", "name": "ERBB2 promotes PTK6 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083475", "species_113592" ], "products": [ "species_29370", "species_10057132", "species_10083480" ], "modifiers": [ [ "species_10083475", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10083477": { "compartment": "compartment_876", "id": "reaction_10083477", "reactome": "R-BTA-8847995", "name": "Activated ERBB2 binds PTK6 (BRK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083473", "species_10057132" ], "products": [ "species_10083475" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061122", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BNA8", "ENSBTAT00000061122" ] }, "reaction_10057700": { "compartment": "compartment_876", "id": "reaction_10057700", "reactome": "R-BTA-1306979", "name": "PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057697", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077601": { "compartment": "compartment_70101", "id": "reaction_10077601", "reactome": "R-BTA-6785636", "name": "Phosphorylated ERBB2 heterodimers bind MEMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057132", "species_10077597" ], "products": [ "species_10077599" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "ENSBTAT00000085928", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056" ] }, "reaction_10077605": { "compartment": "compartment_70101", "id": "reaction_10077605", "reactome": "R-BTA-6785648", "name": "MEMO1 binds RHOA:GTP:DIAPH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073537", "species_10077599" ], "products": [ "species_10077603" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1N5P3", "ENSBTAT00000085928", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10084849": { "compartment": "compartment_876", "id": "reaction_10084849", "reactome": "R-BTA-8863804", "name": "PTPN12 dephosphorylates ERBB2 on tyrosine Y1248", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10057132" ], "products": [ "species_29372", "species_10084842" ], "modifiers": [ [ "species_10084846", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "ENSBTAT00000068950" ] }, "reaction_10061458": { "compartment": "compartment_876", "id": "reaction_10061458", "reactome": "R-BTA-1963563", "name": "MATK (CSK homologous kinase) binds phosphorylated ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061454", "species_10057132" ], "products": [ "species_10061456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069379", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "Q58D16", "ENSBTAT00000069379" ] }, "reaction_10057740": { "compartment": "compartment_70101", "id": "reaction_10057740", "reactome": "R-BTA-1358795", "name": "Deubiquitination of RNF41 by P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057737" ], "products": [ "species_10033408", "species_10055232", "species_10057726" ], "modifiers": [ [ "species_10057737", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057742": { "compartment": "compartment_70101", "id": "reaction_10057742", "reactome": "R-BTA-1358797", "name": "Ubiquitinated RNF41 binds P-USP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057726", "species_10057709" ], "products": [ "species_10057737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033814", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q0IIM6", "ENSBTAT00000033814" ] }, "reaction_10057744": { "compartment": "compartment_70101", "id": "reaction_10057744", "reactome": "R-BTA-1358801", "name": "ERBB3 binds RNF41 ubiquitin ligase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055232", "species_10057066" ], "products": [ "species_10057714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087037", "ENSBTAT00000013790", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057712": { "compartment": "compartment_70101", "id": "reaction_10057712", "reactome": "R-BTA-1358789", "name": "Self-ubiquitination of RNF41", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10055232" ], "products": [ "species_10057709" ], "modifiers": [ [ "species_10055232", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037" ] }, "reaction_10057719": { "compartment": "compartment_70101", "id": "reaction_10057719", "reactome": "R-BTA-1358790", "name": "RNF41 ubiquitinates ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057714", "species_10033408" ], "products": [ "species_10057716", "species_10055232" ], "modifiers": [ [ "species_10057714", "catalyst" ] ], "additional_components": [ "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QR62", "ENSBTAT00000013790", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "A6QR62", "ENSBTAT00000013790", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10057735": { "compartment": "compartment_70101", "id": "reaction_10057735", "reactome": "R-BTA-1358792", "name": "RNF41 ubiquitinates activated ERBB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057730", "species_10033408" ], "products": [ "species_10057732", "species_10055232" ], "modifiers": [ [ "species_10057730", "catalyst" ] ], "additional_components": [ "Q2KI91", "ENSBTAT00000087037", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000087037", "Q2KI91", "ENSBTAT00000087037" ] }, "reaction_10061492": { "compartment": "compartment_876", "id": "reaction_10061492", "reactome": "R-BTA-1963586", "name": "SRC family kinases phosphorylate ERBB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061477", "species_113592" ], "products": [ "species_29370", "species_10061466" ], "modifiers": [ [ "species_10061489", "catalyst" ] ], "additional_components": [ "F1MCQ7", "ENSBTAT00000029056", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "F1MCQ7", "ENSBTAT00000029056", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10066602": { "compartment": "compartment_70101", "id": "reaction_10066602", "reactome": "R-BTA-3165230", "name": "SLC52A1,2,3 transport RIB from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3165253" ], "products": [ "species_196931" ], "modifiers": [ [ "species_10066599", "catalyst" ], [ "species_73524", "inhibitor" ], [ "species_29386", "inhibitor" ] ], "additional_components": [ "A0A3Q1N6I5", "ENSBTAT00000083852", "Q5E9R1", "ENSBTAT00000084768" ] }, "reaction_10041772": { "compartment": "compartment_70101", "id": "reaction_10041772", "reactome": "R-BTA-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73524" ], "products": [ "species_111294", "species_29386" ], "modifiers": [ [ "species_10041769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081315" ] }, "reaction_10041790": { "compartment": "compartment_70101", "id": "reaction_10041790", "reactome": "R-BTA-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29386" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10041787", "catalyst" ] ], "additional_components": [ "F1MNS5", "ENSBTAT00000061365" ] }, "reaction_10041781": { "compartment": "compartment_70101", "id": "reaction_10041781", "reactome": "R-BTA-196950", "name": "2xTRAP hydrolyzes FMN to RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73524" ], "products": [ "species_29372", "species_196931" ], "modifiers": [ [ "species_10041778", "catalyst" ] ], "additional_components": [ "E1B8A0", "ENSBTAT00000006339" ] }, "reaction_10041799": { "compartment": "compartment_70101", "id": "reaction_10041799", "reactome": "R-BTA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10041796", "catalyst" ] ], "additional_components": [ "species_29926", "F6R223", "ENSBTAT00000025762" ] }, "reaction_10056185": { "compartment": "compartment_876", "id": "reaction_10056185", "reactome": "R-BTA-1112602", "name": "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056174" ], "products": [ "species_10056180", "species_29370" ], "modifiers": [ [ "species_10056174", "catalyst" ], [ "species_10056183", "inhibitor" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056123": { "compartment": "compartment_876", "id": "reaction_10056123", "reactome": "R-BTA-1067659", "name": "Assembly of hexameric IL-6 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056119" ], "products": [ "species_10056121" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056188": { "compartment": "compartment_876", "id": "reaction_10056188", "reactome": "R-BTA-1112604", "name": "Phosphorylated STATs are released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180" ], "products": [ "species_10056166", "species_10051764" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342" ] }, "reaction_10056127": { "compartment": "compartment_876", "id": "reaction_10056127", "reactome": "R-BTA-1067667", "name": "IL6 binds IL6R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_10056094" ], "products": [ "species_10056115" ], "modifiers": [ [ "species_10056125", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056176": { "compartment": "compartment_876", "id": "reaction_10056176", "reactome": "R-BTA-1112565", "name": "Tyrosine phosphorylated IL6ST binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10046556" ], "products": [ "species_10056174" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056178": { "compartment": "compartment_70101", "id": "reaction_10056178", "reactome": "R-BTA-1112587", "name": "STAT1 and STAT3 dimers translocate to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056201": { "compartment": "compartment_876", "id": "reaction_10056201", "reactome": "R-BTA-1112708", "name": "PTPN11 binds p-Y759-IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10040231" ], "products": [ "species_10056190" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056168": { "compartment": "compartment_876", "id": "reaction_10056168", "reactome": "R-BTA-1112510", "name": "IL6ST is tyrosine phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056149", "species_113592" ], "products": [ "species_10056166", "species_29370" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056170": { "compartment": "compartment_876", "id": "reaction_10056170", "reactome": "R-BTA-1112514", "name": "JAK activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056121" ], "products": [ "species_10056149", "species_29370" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056205": { "compartment": "compartment_876", "id": "reaction_10056205", "reactome": "R-BTA-1112727", "name": "Serine phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056180", "species_113592" ], "products": [ "species_29370", "species_10056203" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056172": { "compartment": "compartment_70101", "id": "reaction_10056172", "reactome": "R-BTA-1112538", "name": "Phosphorylated STAT1, STAT3 form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051764" ], "products": [ "species_10051766" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10056207": { "compartment": "compartment_876", "id": "reaction_10056207", "reactome": "R-BTA-1112755", "name": "SOCS3 binds IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056166", "species_10051731" ], "products": [ "species_10056183" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000011106", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056110": { "compartment": "compartment_984", "id": "reaction_10056110", "reactome": "R-BTA-1067651", "name": "IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056100" ], "products": [ "species_10056104" ], "modifiers": [ [ "species_10056108", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10091747": { "compartment": "compartment_984", "id": "reaction_10091747", "reactome": "R-BTA-9681294", "name": "IL6R binds IL6R inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056113", "species_9715042" ], "products": [ "species_10056125" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056130": { "compartment": "compartment_984", "id": "reaction_10056130", "reactome": "R-BTA-1067676", "name": "IL6:IL6R-2 binds IL6ST-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056100", "species_10056106" ], "products": [ "species_10056108" ], "modifiers": [], "additional_components": [ "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "ENSBTAT00000023595", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056194": { "compartment": "compartment_876", "id": "reaction_10056194", "reactome": "R-BTA-1112690", "name": "PTPN11 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10056190" ], "products": [ "species_10056192" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10056132": { "compartment": "compartment_876", "id": "reaction_10056132", "reactome": "R-BTA-1067688", "name": "IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10056115" ], "products": [ "species_10056117" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10056199": { "compartment": "compartment_876", "id": "reaction_10056199", "reactome": "R-BTA-1112703", "name": "PTPN11 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10056190" ], "products": [ "species_10056196", "species_29370" ], "modifiers": [ [ "species_10056190", "catalyst" ] ], "additional_components": [ "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587", "F1N339", "ENSBTAT00000002653", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10056102": { "compartment": "compartment_984", "id": "reaction_10056102", "reactome": "R-BTA-1067640", "name": "IL6 binds IL6R-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056098", "species_10056094" ], "products": [ "species_10056100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024587", "ENSBTAT00000019865", "P26892", "ENSBTAT00000019865", "E1BJQ3", "ENSBTAT00000024587" ] }, "reaction_10087338": { "compartment": "compartment_984", "id": "reaction_10087338", "reactome": "R-BTA-8940998", "name": "IL36RN, IL1F10 bind IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087334", "species_10083514" ], "products": [ "species_10087336" ], "modifiers": [], "additional_components": [ "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "F1MWT5", "ENSBTAT00000023970", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10083522": { "compartment": "compartment_984", "id": "reaction_10083522", "reactome": "R-BTA-8848316", "name": "IL36 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083510", "species_10083514" ], "products": [ "species_10083516" ], "modifiers": [ [ "species_10083520", "inhibitor" ] ], "additional_components": [ "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "G3MX81", "ENSBTAT00000065203", "F1N2N4", "ENSBTAT00000002696", "F1MYY4", "ENSBTAT00000045402", "ENSBTAT00000023970" ] }, "reaction_10050024": { "compartment": "compartment_70101", "id": "reaction_10050024", "reactome": "R-BTA-448678", "name": "CTSG cleaves CASP1(1-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050013" ], "products": [ "species_10050007", "species_10050005", "species_10050017", "species_10050015" ], "modifiers": [ [ "species_10050021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000072083", "ENSBTAT00000054741" ] }, "reaction_10050011": { "compartment": "compartment_70101", "id": "reaction_10050011", "reactome": "R-BTA-448673", "name": "Formation of caspase-1 p10/p20 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050007", "species_10050005" ], "products": [ "species_10050009" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072083", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10050028": { "compartment": "compartment_70101", "id": "reaction_10050028", "reactome": "R-BTA-448702", "name": "Caspase-1 active tetramer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050009" ], "products": [ "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089595": { "compartment": "compartment_984", "id": "reaction_10089595", "reactome": "R-BTA-9007901", "name": "IL1F10 binds IL1RL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332", "species_10083514" ], "products": [ "species_10089593" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000007489", "F1N3K3", "ENSBTAT00000007489", "E1BD32", "ENSBTAT00000023975" ] }, "reaction_10089597": { "compartment": "compartment_984", "id": "reaction_10089597", "reactome": "R-BTA-9008043", "name": "MAPK8 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037699", "species_113592" ], "products": [ "species_29370", "species_10039514" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10089591": { "compartment": "compartment_984", "id": "reaction_10089591", "reactome": "R-BTA-9007882", "name": "IL1F10 is cleaved", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087332" ], "products": [ "species_10089589", "species_10089587" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023975", "ENSBTAT00000023975", "ENSBTAT00000023975" ] }, "reaction_10089625": { "compartment": "compartment_70101", "id": "reaction_10089625", "reactome": "R-BTA-9008696", "name": "IL37(?-218) translocates from the cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089617" ], "products": [ "species_10089623" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089819": { "compartment": "compartment_70101", "id": "reaction_10089819", "reactome": "R-BTA-9012556", "name": "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089810" ], "products": [ "species_10089816" ], "modifiers": [ [ "species_10089810", "catalyst" ] ], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10089615": { "compartment": "compartment_70101", "id": "reaction_10089615", "reactome": "R-BTA-9008684", "name": "TBK1 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_113592" ], "products": [ "species_29370", "species_10089613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000023134" ] }, "reaction_10083537": { "compartment": "compartment_984", "id": "reaction_10083537", "reactome": "R-BTA-8848335", "name": "IL37 binds IL18R1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083527", "species_10083531" ], "products": [ "species_10083535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001371", "ENSBTAT00000029311", "E1BLE5", "ENSBTAT00000029311", "F1MJ29", "ENSBTAT00000001371" ] }, "reaction_10089843": { "compartment": "compartment_70101", "id": "reaction_10089843", "reactome": "R-BTA-9012689", "name": "IL37(1-?) and IL37 (?-) dissocates from IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089816" ], "products": [ "species_10089814", "species_10089617", "species_10050026" ], "modifiers": [], "additional_components": [ "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311", "ENSBTAT00000029311", "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083" ] }, "reaction_10089621": { "compartment": "compartment_70101", "id": "reaction_10089621", "reactome": "R-BTA-9008694", "name": "IL37, IL37(?-218) translocates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619" ], "products": [ "species_10083531" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "ENSBTAT00000029311" ] }, "reaction_10089812": { "compartment": "compartment_70101", "id": "reaction_10089812", "reactome": "R-BTA-9012542", "name": "IL37 binds 2x(CASP1(120-197):CASP1(317-404))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089619", "species_10050026" ], "products": [ "species_10089810" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029311", "A0A3Q1MFA5", "ENSBTAT00000072083", "A0A3Q1MFA5", "ENSBTAT00000072083", "E1BLE5", "ENSBTAT00000029311" ] }, "reaction_10049721": { "compartment": "compartment_876", "id": "reaction_10049721", "reactome": "R-BTA-445757", "name": "IL1 receptor antagonist protein binds Interleukin 1 receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049717", "species_10049713" ], "products": [ "species_10049719" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087066", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "F1ML75", "ENSBTAT00000006938", "Q2KIE7", "ENSBTAT00000008322", "A0A3Q1MKE9", "ENSBTAT00000087066" ] }, "reaction_10043867": { "compartment": "compartment_70101", "id": "reaction_10043867", "reactome": "R-BTA-209087", "name": "IKBA is phosphorylated by Phospho IKKB kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043854" ], "products": [ "species_10043858", "species_29370" ], "modifiers": [ [ "species_10043864", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022183", "ENSBTAT00000022183", "ENSBTAT00000009995" ] }, "reaction_10091757": { "compartment": "compartment_984", "id": "reaction_10091757", "reactome": "R-BTA-9681763", "name": "IL1R1 binds IL1R1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9681804", "species_10049707" ], "products": [ "species_10091755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006938", "F1ML75", "ENSBTAT00000006938" ] }, "reaction_10050428": { "compartment": "compartment_70101", "id": "reaction_10050428", "reactome": "R-BTA-450827", "name": "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050418", "species_113592" ], "products": [ "species_29370", "species_10050425" ], "modifiers": [ [ "species_10050418", "catalyst" ] ], "additional_components": [ "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10050420": { "compartment": "compartment_70101", "id": "reaction_10050420", "reactome": "R-BTA-450690", "name": "hp-IRAK1,hp-IRAK4 bind Pellino1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050416", "species_10050412" ], "products": [ "species_10050418" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067567", "ENSBTAT00000028115", "Q1RMT8", "ENSBTAT00000028115", "A0A3Q1LQ14", "ENSBTAT00000067567" ] }, "reaction_10051095": { "compartment": "compartment_70101", "id": "reaction_10051095", "reactome": "R-BTA-507719", "name": "p62:MEKK3 binds to TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051091", "species_10039473" ], "products": [ "species_10051093" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1LPF2", "ENSBTAT00000081015" ] }, "reaction_10085017": { "compartment": "compartment_7660", "id": "reaction_10085017", "reactome": "R-BTA-8865613", "name": "BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084951", "species_10085013" ], "products": [ "species_10085015" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018087", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTQ0", "ENSBTAT00000018087" ] }, "reaction_10091731": { "compartment": "compartment_70101", "id": "reaction_10091731", "reactome": "R-BTA-9679028", "name": "JAK3 binds JAK3 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_9678772" ], "products": [ "species_10091729" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10089251": { "compartment": "compartment_876", "id": "reaction_10089251", "reactome": "R-BTA-8983059", "name": "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089244" ], "products": [ "species_29370", "species_10089248" ], "modifiers": [ [ "species_10089244", "catalyst" ] ], "additional_components": [ "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10089253": { "compartment": "compartment_984", "id": "reaction_10089253", "reactome": "R-BTA-8983061", "name": "TSLP binds CRLF2:IL7R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089234", "species_10089240" ], "products": [ "species_10089242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072042", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "E1BPM3", "ENSBTAT00000026608", "G3X7G0", "ENSBTAT00000026955", "A0A3Q1M5G1", "ENSBTAT00000072042" ] }, "reaction_10087787": { "compartment": "compartment_70101", "id": "reaction_10087787", "reactome": "R-BTA-8950731", "name": "CRLF1:IL27 translocates to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087772" ], "products": [ "species_10087785" ], "modifiers": [], "additional_components": [ "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10049946": { "compartment": "compartment_984", "id": "reaction_10049946", "reactome": "R-BTA-448421", "name": "Interleukin-27 translocates from the ER lumen to the extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049938" ], "products": [ "species_10049944" ], "modifiers": [], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046" ] }, "reaction_10087726": { "compartment": "compartment_876", "id": "reaction_10087726", "reactome": "R-BTA-8950340", "name": "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087711" ], "products": [ "species_29370", "species_10087723" ], "modifiers": [ [ "species_10087711", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087774": { "compartment": "compartment_70101", "id": "reaction_10087774", "reactome": "R-BTA-8950504", "name": "IL27 binds CRLF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087770", "species_10087768" ], "products": [ "species_10087772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083936", "ENSBTAT00000074594", "A0A3Q1MQM6", "ENSBTAT00000074594", "A0A3Q1LK84", "ENSBTAT00000083936" ] }, "reaction_10087793": { "compartment": "compartment_876", "id": "reaction_10087793", "reactome": "R-BTA-8950766", "name": "IL27RA dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049962" ], "products": [ "species_10087791" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022524", "A5D7S4", "ENSBTAT00000022524" ] }, "reaction_10049970": { "compartment": "compartment_984", "id": "reaction_10049970", "reactome": "R-BTA-448427", "name": "Interleukin-27 binds Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049958", "species_10049964", "species_10049944" ], "products": [ "species_10049966" ], "modifiers": [ [ "species_10049968", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "ENSBTAT00000022524" ] }, "reaction_10087671": { "compartment": "compartment_984", "id": "reaction_10087671", "reactome": "R-BTA-8950210", "name": "Interleukin-27 dissociates from Interleukin-27 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049966" ], "products": [ "species_10049958", "species_10049964", "species_10049944" ], "modifiers": [ [ "species_10049940", "inhibitor" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "ENSBTAT00000083936" ] }, "reaction_10087783": { "compartment": "compartment_876", "id": "reaction_10087783", "reactome": "R-BTA-8950537", "name": "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049966" ], "products": [ "species_29370", "species_10087711" ], "modifiers": [ [ "species_10049966", "catalyst" ] ], "additional_components": [ "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "A5D7S4", "ENSBTAT00000022524", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10087766": { "compartment": "compartment_70101", "id": "reaction_10087766", "reactome": "R-BTA-8950485", "name": "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087736" ], "products": [ "species_10087734", "species_29370" ], "modifiers": [ [ "species_10087736", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A5D7S4", "ENSBTAT00000022524", "A0A3Q1LK84", "ENSBTAT00000083936", "A6QPV0", "ENSBTAT00000017046", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089321": { "compartment": "compartment_876", "id": "reaction_10089321", "reactome": "R-BTA-8983834", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089313" ], "products": [ "species_10089319", "species_29370" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "F1N0D6", "ENSBTAT00000004101", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089329": { "compartment": "compartment_876", "id": "reaction_10089329", "reactome": "R-BTA-8983835", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089325" ], "products": [ "species_29370", "species_10089327" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089331": { "compartment": "compartment_876", "id": "reaction_10089331", "reactome": "R-BTA-8983841", "name": "STAT1 associates with IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046556", "species_10089323" ], "products": [ "species_10089325" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10087763": { "compartment": "compartment_70101", "id": "reaction_10087763", "reactome": "R-BTA-8950453", "name": "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087752" ], "products": [ "species_29370", "species_10087760" ], "modifiers": [ [ "species_10087752", "catalyst" ] ], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "E1BD36", "ENSBTAT00000023595" ] }, "reaction_10089333": { "compartment": "compartment_876", "id": "reaction_10089333", "reactome": "R-BTA-8983845", "name": "p-STAT1 dissociates from IL6ST:IL6ST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089327" ], "products": [ "species_10087758", "species_10089323" ], "modifiers": [], "additional_components": [ "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "A6QPV0", "ENSBTAT00000017046", "E1BCP6", "ENSBTAT00000015986", "E1BD36", "ENSBTAT00000023595", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10087780": { "compartment": "compartment_70101", "id": "reaction_10087780", "reactome": "R-BTA-8950522", "name": "p-STAT1:p-STAT4 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087776" ], "products": [ "species_10087778" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10049928": { "compartment": "compartment_984", "id": "reaction_10049928", "reactome": "R-BTA-447130", "name": "Interleukin-23 binds interleukin-23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049924", "species_10049904", "species_10049914" ], "products": [ "species_10049926" ], "modifiers": [], "additional_components": [ "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MZJ0", "ENSBTAT00000019945", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10087789": { "compartment": "compartment_984", "id": "reaction_10087789", "reactome": "R-BTA-8950741", "name": "IL12B:IL23A translocates from ER lumen to extracellular space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087669" ], "products": [ "species_10049904" ], "modifiers": [], "additional_components": [ "A0A3Q1LXM0", "ENSBTAT00000077926", "F1MSN4", "ENSBTAT00000005745", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926" ] }, "reaction_10087697": { "compartment": "compartment_70101", "id": "reaction_10087697", "reactome": "R-BTA-8950269", "name": "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087690" ], "products": [ "species_29370", "species_10087694" ], "modifiers": [ [ "species_10087690", "catalyst" ] ], "additional_components": [ "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584", "F1N0R2", "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10088498": { "compartment": "compartment_70101", "id": "reaction_10088498", "reactome": "R-BTA-8952749", "name": "STAT4 binds p-Y-IL23R in IL23:IL23 receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087674", "species_10087688" ], "products": [ "species_10087690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030584", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "G3MX29", "ENSBTAT00000064950", "F1MCX4", "ENSBTAT00000015532", "F1MSN4", "ENSBTAT00000005745", "A0A3Q1LXM0", "ENSBTAT00000077926", "E1BCP6", "ENSBTAT00000015986", "F1MZJ0", "ENSBTAT00000019945", "F1N0R2", "ENSBTAT00000030584" ] }, "reaction_10051194": { "compartment": "compartment_70101", "id": "reaction_10051194", "reactome": "R-BTA-508451", "name": "PTK2B is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051187" ], "products": [ "species_10051192" ], "modifiers": [], "additional_components": [ "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857", "E1BEL4", "ENSBTAT00000027857", "A0A3Q1LVP1", "ENSBTAT00000084967" ] }, "reaction_10051196": { "compartment": "compartment_70101", "id": "reaction_10051196", "reactome": "R-BTA-508513", "name": "PTK2B binds JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050577", "species_10047260" ], "products": [ "species_10051187" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027857", "ENSBTAT00000084967", "A0A3Q1LVP1", "ENSBTAT00000084967", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10050527": { "compartment": "compartment_70101", "id": "reaction_10050527", "reactome": "R-BTA-451900", "name": "IL2RB binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050134", "species_10049950" ], "products": [ "species_10050136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074166", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166" ] }, "reaction_10089736": { "compartment": "compartment_70101", "id": "reaction_10089736", "reactome": "R-BTA-9011748", "name": "IL9R binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089732", "species_10049950" ], "products": [ "species_10089734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009944", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MTF9", "ENSBTAT00000009944" ] }, "reaction_10089363": { "compartment": "compartment_70101", "id": "reaction_10089363", "reactome": "R-BTA-8985943", "name": "p-Y701-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089359" ], "products": [ "species_10089361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10050619": { "compartment": "compartment_876", "id": "reaction_10050619", "reactome": "R-BTA-453104", "name": "Phosphorylated SHC1 recruits GRB2:GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050571", "species_10050569" ], "products": [ "species_10050617" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10050623": { "compartment": "compartment_70101", "id": "reaction_10050623", "reactome": "R-BTA-453111", "name": "Phosphorylated SHC recruits GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10050569" ], "products": [ "species_10050621" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10052254": { "compartment": "compartment_876", "id": "reaction_10052254", "reactome": "R-BTA-912527", "name": "SHC1 mediates cytokine-induced phosphorylation of GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050617" ], "products": [ "species_29370", "species_10052252" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1LQZ1", "ENSBTAT00000074166", "F1N0D6", "ENSBTAT00000004101", "A2VE30", "ENSBTAT00000054113", "E1BEL4", "ENSBTAT00000027857" ] }, "reaction_10052337": { "compartment": "compartment_70101", "id": "reaction_10052337", "reactome": "R-BTA-913374", "name": "Phosphorylated SHC1 recruits SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052333", "species_10050569" ], "products": [ "species_10052335" ], "modifiers": [], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BBJ7", "ENSBTAT00000025510", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10052343": { "compartment": "compartment_70101", "id": "reaction_10052343", "reactome": "R-BTA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052339", "species_10035485" ], "products": [ "species_10052341" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "Q0IIE2", "ENSBTAT00000075224", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529" ] }, "reaction_10089291": { "compartment": "compartment_17940", "id": "reaction_10089291", "reactome": "R-BTA-8983335", "name": "IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255" ], "products": [ "species_10089289" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089311": { "compartment": "compartment_70101", "id": "reaction_10089311", "reactome": "R-BTA-8983384", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089307", "species_10089305" ], "products": [ "species_10089309" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089267": { "compartment": "compartment_70101", "id": "reaction_10089267", "reactome": "R-BTA-8983300", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089255", "species_113592" ], "products": [ "species_29370", "species_10089264" ], "modifiers": [ [ "species_10089255", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LQZ1", "ENSBTAT00000074166", "E1BEL4", "ENSBTAT00000027857", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089269": { "compartment": "compartment_984", "id": "reaction_10089269", "reactome": "R-BTA-8983307", "name": "IL15 binds IL15RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050128", "species_10050124" ], "products": [ "species_10050130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083836", "ENSBTAT00000084366", "Q28028", "ENSBTAT00000084366", "A0A3Q1M783", "ENSBTAT00000083836" ] }, "reaction_10089689": { "compartment": "compartment_984", "id": "reaction_10089689", "reactome": "R-BTA-9009485", "name": "IL34:CSF1 binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089685", "species_10077839" ], "products": [ "species_10089687" ], "modifiers": [], "additional_components": [ "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179", "ENSBTAT00000016977", "A7Z067", "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10089691": { "compartment": "compartment_984", "id": "reaction_10089691", "reactome": "R-BTA-9009488", "name": "IL34 binds CSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089683", "species_10049979" ], "products": [ "species_10089685" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076179", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A0A3Q1LMK4", "ENSBTAT00000076179" ] }, "reaction_10090027": { "compartment": "compartment_984", "id": "reaction_10090027", "reactome": "R-BTA-9014052", "name": "TXLNA (IL14) binds syntaxin3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090023", "species_10050140" ], "products": [ "species_10090025" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069233", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A3Q1LYB4", "ENSBTAT00000069233" ] }, "reaction_10049983": { "compartment": "compartment_984", "id": "reaction_10049983", "reactome": "R-BTA-448632", "name": "IL34 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049979" ], "products": [ "species_10049981" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664" ] }, "reaction_10090031": { "compartment": "compartment_984", "id": "reaction_10090031", "reactome": "R-BTA-9014074", "name": "TXLNA (IL14) binds syntaxin4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045527", "species_10050140" ], "products": [ "species_10090029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009899", "ENSBTAT00000017100", "E1BGS4", "ENSBTAT00000017100", "A0A452DIB2", "ENSBTAT00000009899" ] }, "reaction_10077843": { "compartment": "compartment_876", "id": "reaction_10077843", "reactome": "R-BTA-6787820", "name": "IL34 dimer binds CSF1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077839", "species_10049981" ], "products": [ "species_10077841" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016977", "A6QL48", "ENSBTAT00000076664", "A6QL48", "ENSBTAT00000076664", "A7Z067", "ENSBTAT00000016977" ] }, "reaction_10077945": { "compartment": "compartment_17957", "id": "reaction_10077945", "reactome": "R-BTA-6790038", "name": "Expression of HSP90B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10060767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004364" ] }, "reaction_10077723": { "compartment": "compartment_70101", "id": "reaction_10077723", "reactome": "R-BTA-6786097", "name": "p-Y705-STAT3, p-Y641-STAT6 dimerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077719" ], "products": [ "species_10077721" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077870": { "compartment": "compartment_70101", "id": "reaction_10077870", "reactome": "R-BTA-6788622", "name": "p-Y-STATs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077866" ], "products": [ "species_10077868" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10077633": { "compartment": "compartment_876", "id": "reaction_10077633", "reactome": "R-BTA-6785762", "name": "IL13RA1 binds TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049908", "species_10077629" ], "products": [ "species_10077631" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015532", "ENSBTAT00000025754", "G3X7E9", "ENSBTAT00000025754", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10077874": { "compartment": "compartment_70101", "id": "reaction_10077874", "reactome": "R-BTA-6788623", "name": "p-Y-STATs translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077868" ], "products": [ "species_10077872" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10077764": { "compartment": "compartment_70101", "id": "reaction_10077764", "reactome": "R-BTA-6786293", "name": "p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077721" ], "products": [ "species_10077762" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10052302": { "compartment": "compartment_70101", "id": "reaction_10052302", "reactome": "R-BTA-912734", "name": "CBL:CRKL binds RAPGEF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052298", "species_10039707" ], "products": [ "species_10052300" ], "modifiers": [], "additional_components": [ "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052323": { "compartment": "compartment_70101", "id": "reaction_10052323", "reactome": "R-BTA-912790", "name": "CBL binds CRK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052267", "species_10052296" ], "products": [ "species_10052298" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "G3N016", "ENSBTAT00000066024", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10052294": { "compartment": "compartment_70101", "id": "reaction_10052294", "reactome": "R-BTA-912627", "name": "CBL ubiquitinates PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10052269" ], "products": [ "species_10052292" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10051962": { "compartment": "compartment_70101", "id": "reaction_10051962", "reactome": "R-BTA-879934", "name": "Recruitment of SHC1 is mediated by Y593 of the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051923", "species_10035544" ], "products": [ "species_10051960" ], "modifiers": [], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10051949": { "compartment": "compartment_70101", "id": "reaction_10051949", "reactome": "R-BTA-879909", "name": "Activation of STAT5a/b by JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051942", "species_113592" ], "products": [ "species_29370", "species_10051946" ], "modifiers": [ [ "species_10051942", "catalyst" ] ], "additional_components": [ "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10052735": { "compartment": "compartment_876", "id": "reaction_10052735", "reactome": "R-BTA-914036", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052238" ], "products": [ "species_10052732" ], "modifiers": [ [ "species_10052238", "catalyst" ] ], "additional_components": [ "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051966": { "compartment": "compartment_876", "id": "reaction_10051966", "reactome": "R-BTA-879942", "name": "The receptor is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051964" ], "products": [ "species_10051921" ], "modifiers": [], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052321": { "compartment": "compartment_70101", "id": "reaction_10052321", "reactome": "R-BTA-912757", "name": "p-S585-IL3RB binds 14-3-3 proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037660", "species_10052317" ], "products": [ "species_10052319" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "P63103", "ENSBTAT00000000289" ] }, "reaction_10051936": { "compartment": "compartment_70101", "id": "reaction_10051936", "reactome": "R-BTA-879907", "name": "Tyrosine kinases phosphorylate the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051923" ], "modifiers": [ [ "species_10051933", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052240": { "compartment": "compartment_70101", "id": "reaction_10052240", "reactome": "R-BTA-909738", "name": "SHP1 and SHP2 bind the common beta chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047046", "species_10051923" ], "products": [ "species_10052238" ], "modifiers": [], "additional_components": [ "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10051954": { "compartment": "compartment_70101", "id": "reaction_10051954", "reactome": "R-BTA-879910", "name": "JAK2 is phosphorylated, activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051921" ], "products": [ "species_29370", "species_10051951" ], "modifiers": [ [ "species_10051921", "catalyst" ] ], "additional_components": [ "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1LK34", "ENSBTAT00000085850", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052325": { "compartment": "compartment_984", "id": "reaction_10052325", "reactome": "R-BTA-913360", "name": "GM-CSF receptor alpha subunit binds GM-CSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050559", "species_10050555" ], "products": [ "species_10050561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002054", "ENSBTAT00000040022", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054" ] }, "reaction_10052327": { "compartment": "compartment_876", "id": "reaction_10052327", "reactome": "R-BTA-913371", "name": "GM-CSF receptor alpha:GM-CSF binds Bc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051911", "species_10050561" ], "products": [ "species_10051917" ], "modifiers": [], "additional_components": [ "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "E1BCP6", "ENSBTAT00000015986", "F1MXH7", "ENSBTAT00000011947" ] }, "reaction_10089466": { "compartment": "compartment_70101", "id": "reaction_10089466", "reactome": "R-BTA-8987084", "name": "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089459", "species_113592" ], "products": [ "species_10089463", "species_29370" ], "modifiers": [ [ "species_10089459", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089530": { "compartment": "compartment_70101", "id": "reaction_10089530", "reactome": "R-BTA-8987202", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089527", "species_113592" ], "products": [ "species_29370", "species_10089450" ], "modifiers": [ [ "species_10089527", "catalyst" ] ], "additional_components": [ "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532" ] }, "reaction_10089523": { "compartment": "compartment_70101", "id": "reaction_10089523", "reactome": "R-BTA-8987179", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089520" ], "products": [ "species_10089490", "species_29370" ], "modifiers": [ [ "species_10089520", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089427": { "compartment": "compartment_459", "id": "reaction_10089427", "reactome": "R-BTA-8986985", "name": "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089417" ], "products": [ "species_29370", "species_10089424" ], "modifiers": [ [ "species_10089417", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089431": { "compartment": "compartment_70101", "id": "reaction_10089431", "reactome": "R-BTA-8987007", "name": "p-STAT1 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087758" ], "products": [ "species_10089429" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089480": { "compartment": "compartment_70101", "id": "reaction_10089480", "reactome": "R-BTA-8987097", "name": "IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089476", "species_10046556" ], "products": [ "species_10089478" ], "modifiers": [], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089453": { "compartment": "compartment_70101", "id": "reaction_10089453", "reactome": "R-BTA-8987040", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089450" ], "products": [ "species_10089413", "species_29370" ], "modifiers": [ [ "species_10089450", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "G3MZC4", "ENSBTAT00000063825" ] }, "reaction_10089516": { "compartment": "compartment_70101", "id": "reaction_10089516", "reactome": "R-BTA-8987150", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089478", "species_113592" ], "products": [ "species_29370", "species_10089513" ], "modifiers": [ [ "species_10089478", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089455": { "compartment": "compartment_70101", "id": "reaction_10089455", "reactome": "R-BTA-8987043", "name": "IL22RA1 binds JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050036", "species_10049950" ], "products": [ "species_10050038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001455", "ENSBTAT00000004101", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089536": { "compartment": "compartment_70101", "id": "reaction_10089536", "reactome": "R-BTA-8987218", "name": "p-STAT1 dimer translocates from the cytosol to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089429" ], "products": [ "species_10089534" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089538": { "compartment": "compartment_70101", "id": "reaction_10089538", "reactome": "R-BTA-8987220", "name": "IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089518", "species_10089484" ], "products": [ "species_10089520" ], "modifiers": [], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089442": { "compartment": "compartment_70101", "id": "reaction_10089442", "reactome": "R-BTA-8987012", "name": "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10089435" ], "products": [ "species_29370", "species_10089439" ], "modifiers": [ [ "species_10089435", "catalyst" ] ], "additional_components": [ "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455", "F1MJR4", "ENSBTAT00000001455", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "F1N0D6", "ENSBTAT00000004101", "F1MJR4", "ENSBTAT00000001455" ] }, "reaction_10089506": { "compartment": "compartment_70101", "id": "reaction_10089506", "reactome": "R-BTA-8987120", "name": "JAK1 binds IFNLR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10049999" ], "products": [ "species_10050001" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000001456", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10089540": { "compartment": "compartment_70101", "id": "reaction_10089540", "reactome": "R-BTA-8987266", "name": "IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089415", "species_10089413" ], "products": [ "species_10089417" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10089444": { "compartment": "compartment_70101", "id": "reaction_10089444", "reactome": "R-BTA-8987033", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089424" ], "products": [ "species_10089413", "species_10089422" ], "modifiers": [], "additional_components": [ "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1MCX4", "ENSBTAT00000015532", "G3MZC4", "ENSBTAT00000063825", "E1B7G0", "ENSBTAT00000001456", "F1N0D6", "ENSBTAT00000004101", "F1N0R2", "ENSBTAT00000030584", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10089511": { "compartment": "compartment_70101", "id": "reaction_10089511", "reactome": "R-BTA-8987129", "name": "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089508", "species_113592" ], "products": [ "species_10089476", "species_29370" ], "modifiers": [ [ "species_10089508", "catalyst" ] ], "additional_components": [ "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089446": { "compartment": "compartment_70101", "id": "reaction_10089446", "reactome": "R-BTA-8987039", "name": "JAK1 binds IL20RA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049950", "species_10050044" ], "products": [ "species_10050046" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004101", "ENSBTAT00000066507", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101" ] }, "reaction_10050054": { "compartment": "compartment_876", "id": "reaction_10050054", "reactome": "R-BTA-448744", "name": "IL20RA binds IL20RB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050032", "species_10050046" ], "products": [ "species_10050048" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919" ] }, "reaction_10089542": { "compartment": "compartment_70101", "id": "reaction_10089542", "reactome": "R-BTA-8987270", "name": "p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089513" ], "products": [ "species_10089476", "species_10087758" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "A6QNP0", "ENSBTAT00000010919", "A0A3Q1M5P5", "ENSBTAT00000066507", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000084342" ] }, "reaction_10061449": { "compartment": "compartment_70101", "id": "reaction_10061449", "reactome": "R-BTA-1912382", "name": "Mature NOTCH heterodimer traffics to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061434" ], "products": [ "species_10061443" ], "modifiers": [ [ "species_10061447", "inhibitor" ] ], "additional_components": [ "G3X812", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "ENSBTAT00000084118" ] }, "reaction_10090834": { "compartment": "compartment_13231", "id": "reaction_10090834", "reactome": "R-BTA-9604308", "name": "NICD4 traffics to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090824" ], "products": [ "species_10044414" ], "modifiers": [ [ "species_10090832", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000050083", "ENSBTAT00000050083", "G3X812", "ENSBTAT00000050083", "P63103", "ENSBTAT00000000289" ] }, "reaction_10078393": { "compartment": "compartment_5460", "id": "reaction_10078393", "reactome": "R-BTA-6793590", "name": "LIPT2 transfers octanoyl group to GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078383", "species_10076429" ], "products": [ "species_10038774", "species_10078386" ], "modifiers": [ [ "species_10078390", "catalyst" ] ], "additional_components": [ "CHEBI:25650", "G3X6L0", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000008382", "ENSBTAT00000008936", "ENSBTAT00000010820" ] }, "reaction_10052056": { "compartment": "compartment_5460", "id": "reaction_10052056", "reactome": "R-BTA-904864", "name": "Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_904849", "species_379697" ], "products": [ "species_159549", "species_113557" ], "modifiers": [ [ "species_10052053", "catalyst" ] ], "additional_components": [ "F1MLG7", "ENSBTAT00000010113" ] }, "reaction_10047019": { "compartment": "compartment_17951", "id": "reaction_10047019", "reactome": "R-BTA-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_389822" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078701": { "compartment": "compartment_70101", "id": "reaction_10078701", "reactome": "R-BTA-6798317", "name": "GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_29424" ], "products": [ "species_5359017", "species_71285" ], "modifiers": [ [ "species_10078698", "catalyst" ] ], "additional_components": [ "A0A3Q1LMP5", "ENSBTAT00000079667", "A0A3Q1M678", "ENSBTAT00000080669" ] }, "reaction_10047022": { "compartment": "compartment_17951", "id": "reaction_10047022", "reactome": "R-BTA-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_141343", "species_389678" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10047016", "catalyst" ] ], "additional_components": [ "species_73524", "E1BC79", "ENSBTAT00000061291" ] }, "reaction_10078366": { "compartment": "compartment_5460", "id": "reaction_10078366", "reactome": "R-BTA-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078353", "species_10076427" ], "products": [ "species_10078359", "species_10076429" ], "modifiers": [ [ "species_10078363", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000079686", "ENSBTAT00000008936", "ENSBTAT00000005171" ] }, "reaction_10077458": { "compartment": "compartment_5460", "id": "reaction_10077458", "reactome": "R-BTA-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784236", "species_113587" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10078402": { "compartment": "compartment_5460", "id": "reaction_10078402", "reactome": "R-BTA-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_10078386", "species_2162265" ], "products": [ "species_379705", "species_6793613", "species_10076427" ], "modifiers": [ [ "species_10078399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "ENSBTAT00000008936", "Q5BIP7", "ENSBTAT00000019299", "CHEBI:49883" ] }, "reaction_10076441": { "compartment": "compartment_5460", "id": "reaction_10076441", "reactome": "R-BTA-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10076427" ], "products": [ "species_10076431", "species_29376" ], "modifiers": [ [ "species_10076438", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008936", "P20821", "ENSBTAT00000008936", "CHEBI:14949", "E1BJQ1", "ENSBTAT00000036700" ] }, "reaction_10076459": { "compartment": "compartment_5460", "id": "reaction_10076459", "reactome": "R-BTA-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10076443" ], "products": [ "species_113529", "species_29362", "species_10076427" ], "modifiers": [ [ "species_10076456", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000008936", "species_113596", "F1N206", "ENSBTAT00000033787" ] }, "reaction_10076450": { "compartment": "compartment_5460", "id": "reaction_10076450", "reactome": "R-BTA-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_10076431" ], "products": [ "species_5693978", "species_5693984", "species_10076443" ], "modifiers": [ [ "species_10076447", "catalyst" ] ], "additional_components": [ "P20821", "ENSBTAT00000008936", "CHEBI:14949", "P20821", "ENSBTAT00000008936", "CHEBI:50746", "ENSBTAT00000002992" ] }, "reaction_10051737": { "compartment": "compartment_70101", "id": "reaction_10051737", "reactome": "R-BTA-873918", "name": "Transphosphorylation of JAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_113592" ], "products": [ "species_29370", "species_10051722" ], "modifiers": [ [ "species_10051716", "catalyst" ], [ "species_10043836", "inhibitor" ], [ "species_10051735", "inhibitor" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "ENSBTAT00000077529", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10091723": { "compartment": "compartment_70101", "id": "reaction_10091723", "reactome": "R-BTA-9678561", "name": "IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678984", "species_10051743" ], "products": [ "species_10051778" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10051771": { "compartment": "compartment_70101", "id": "reaction_10051771", "reactome": "R-BTA-873922", "name": "Phosphorylation of STAT1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051760", "species_113592" ], "products": [ "species_29370", "species_10051768" ], "modifiers": [ [ "species_10051760", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051786": { "compartment": "compartment_70101", "id": "reaction_10051786", "reactome": "R-BTA-873927", "name": "Release of STAT1 dimer from active receptor unit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051784" ], "products": [ "species_10051756", "species_10051690" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051774": { "compartment": "compartment_70101", "id": "reaction_10051774", "reactome": "R-BTA-873924", "name": "Phosphorylation of IFNGR1 by JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051722" ], "products": [ "species_29370", "species_10051756" ], "modifiers": [ [ "species_10051722", "catalyst" ] ], "additional_components": [ "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051696": { "compartment": "compartment_13231", "id": "reaction_10051696", "reactome": "R-BTA-873917", "name": "Translocation of STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051690" ], "products": [ "species_10051694" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10052067": { "compartment": "compartment_70101", "id": "reaction_10052067", "reactome": "R-BTA-909552", "name": "Phosphorylation of STAT1 at Ser727", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051768" ], "products": [ "species_29370", "species_10051784" ], "modifiers": [ [ "species_10052064", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10051762": { "compartment": "compartment_70101", "id": "reaction_10051762", "reactome": "R-BTA-873921", "name": "Binding of STAT1 to p-IFNGR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051758", "species_10051756" ], "products": [ "species_10051760" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10051818": { "compartment": "compartment_7660", "id": "reaction_10051818", "reactome": "R-BTA-877281", "name": "PIAS1 binds p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051814", "species_10051796", "species_10051694" ], "products": [ "species_10051816" ], "modifiers": [], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "ENSBTAT00000083334", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ML58", "ENSBTAT00000083334", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456" ] }, "reaction_10055967": { "compartment": "compartment_7660", "id": "reaction_10055967", "reactome": "R-BTA-997326", "name": "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10051694" ], "products": [ "species_113550", "species_10055960" ], "modifiers": [ [ "species_10055964", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "ENSBTAT00000084342", "ENSBTAT00000074168" ] }, "reaction_10051792": { "compartment": "compartment_70101", "id": "reaction_10051792", "reactome": "R-BTA-877269", "name": "SOCS-1 and SOCS-3 binds to p-JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051716", "species_10051733" ], "products": [ "species_10051735" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051780": { "compartment": "compartment_984", "id": "reaction_10051780", "reactome": "R-BTA-873926", "name": "IFNG dimer binds IFNGR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051702", "species_10051743" ], "products": [ "species_10051745" ], "modifiers": [ [ "species_10051778", "inhibitor" ], [ "species_10051776", "inhibitor" ] ], "additional_components": [ "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10051748": { "compartment": "compartment_70101", "id": "reaction_10051748", "reactome": "R-BTA-873919", "name": "Phosphorylation of JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051745" ], "products": [ "species_10051716", "species_29370" ], "modifiers": [ [ "species_10051745", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634", "F1N0D6", "ENSBTAT00000004101", "A0A3Q1LLQ7", "ENSBTAT00000066996", "E1BCP6", "ENSBTAT00000015986", "P07353", "ENSBTAT00000016634" ] }, "reaction_10078682": { "compartment": "compartment_876", "id": "reaction_10078682", "reactome": "R-BTA-6798258", "name": "PRTPRF, PTPRS, PTPRD bind LRRC4B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078678", "species_10046864" ], "products": [ "species_10078680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000043330", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "E1BPK8", "ENSBTAT00000043330" ] }, "reaction_10078674": { "compartment": "compartment_876", "id": "reaction_10078674", "reactome": "R-BTA-6798257", "name": "PTPRS binds NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046862", "species_10078670" ], "products": [ "species_10078672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074444", "ENSBTAT00000064547", "G3N3T6", "ENSBTAT00000064547", "A0A3Q1MZF8", "ENSBTAT00000074444" ] }, "reaction_10046868": { "compartment": "compartment_70101", "id": "reaction_10046868", "reactome": "R-BTA-388824", "name": "PTPRF, PTPRS, PTPRD bind Liprins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046854", "species_10046864" ], "products": [ "species_10046866" ], "modifiers": [], "additional_components": [ "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1MBH3", "ENSBTAT00000073078", "A0A3Q1M5L6", "ENSBTAT00000081984", "A0A3Q1LQ22", "ENSBTAT00000075872", "A0A3Q1M5X2", "ENSBTAT00000069454" ] }, "reaction_10078566": { "compartment": "compartment_876", "id": "reaction_10078566", "reactome": "R-BTA-6797803", "name": "PTPRD binds SLITRK1-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078562", "species_10046858" ], "products": [ "species_10078564" ], "modifiers": [], "additional_components": [ "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827", "ENSBTAT00000066459", "A0A3Q1M422", "ENSBTAT00000066459", "F1N5L8", "ENSBTAT00000015639", "F1MJJ9", "ENSBTAT00000054494", "E1B8X9", "ENSBTAT00000013364", "G3N2N1", "ENSBTAT00000072588", "F1MSM8", "ENSBTAT00000005757", "F1N513", "ENSBTAT00000022827" ] }, "reaction_10034944": { "compartment": "compartment_70101", "id": "reaction_10034944", "reactome": "R-BTA-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_113592" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10034941", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10036903": { "compartment": "compartment_70101", "id": "reaction_10036903", "reactome": "R-BTA-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10034933", "catalyst" ], [ "species_29372", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q2HJ58", "ENSBTAT00000026261" ] }, "reaction_10076792": { "compartment": "compartment_70101", "id": "reaction_10076792", "reactome": "R-BTA-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694568", "species_29356" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10076789", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022154" ] }, "reaction_10059002": { "compartment": "compartment_12045", "id": "reaction_10059002", "reactome": "R-BTA-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059853": { "compartment": "compartment_984", "id": "reaction_10059853", "reactome": "R-BTA-1602398", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602375", "species_109276" ], "products": [ "species_1602372", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10059004": { "compartment": "compartment_12045", "id": "reaction_10059004", "reactome": "R-BTA-1482887", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10084526": { "compartment": "compartment_70101", "id": "reaction_10084526", "reactome": "R-BTA-8858298", "name": "HRASLS transfer acyl group from PC to PE to form NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_1500581" ], "products": [ "species_5694568", "species_6814253" ], "modifiers": [ [ "species_10084523", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451" ] }, "reaction_10058899": { "compartment": "compartment_12045", "id": "reaction_10058899", "reactome": "R-BTA-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498738" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058885": { "compartment": "compartment_12045", "id": "reaction_10058885", "reactome": "R-BTA-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10058882", "catalyst" ] ], "additional_components": [ "G8JL05", "ENSBTAT00000054491", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058980": { "compartment": "compartment_12045", "id": "reaction_10058980", "reactome": "R-BTA-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500581" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10058977", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10046888": { "compartment": "compartment_876", "id": "reaction_10046888", "reactome": "R-BTA-388828", "name": "PD-1 binds B7DC and B7H1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046882", "species_10046872" ], "products": [ "species_10046884" ], "modifiers": [ [ "species_10046886", "inhibitor" ] ], "additional_components": [ "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165", "A0A3Q1M2W6", "ENSBTAT00000083184", "C5NU11", "ENSBTAT00000008067", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10091743": { "compartment": "compartment_876", "id": "reaction_10091743", "reactome": "R-BTA-9679421", "name": "PDCD1 binds PDCD1 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679406", "species_10046872" ], "products": [ "species_10046886" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079165", "A0A3Q1MQR6", "ENSBTAT00000079165" ] }, "reaction_10064439": { "compartment": "compartment_70101", "id": "reaction_10064439", "reactome": "R-BTA-2161500", "name": "abacavir [extracellular] => abacavir [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161525" ], "products": [ "species_2161185" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10064584": { "compartment": "compartment_70101", "id": "reaction_10064584", "reactome": "R-BTA-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_2162081", "species_73473" ], "modifiers": [ [ "species_10034181", "catalyst" ] ], "additional_components": [ "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10075063": { "compartment": "compartment_70101", "id": "reaction_10075063", "reactome": "R-BTA-5686073", "name": "GRB2-1:SOS1 binds p-3Y-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050549", "species_10035491" ], "products": [ "species_10075061" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10086241": { "compartment": "compartment_7660", "id": "reaction_10086241", "reactome": "R-BTA-8878220", "name": "RUNX3 binds the NOTCH1 coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10086237" ], "products": [ "species_10086239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MF28", "ENSBTAT00000078064", "Q1JQE0", "ENSBTAT00000010697", "Q3SZ41", "ENSBTAT00000004696", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10072913": { "compartment": "compartment_876", "id": "reaction_10072913", "reactome": "R-BTA-5654148", "name": "p-4Y-PLCG1 dissociates from activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072911" ], "products": [ "species_10043237", "species_10065265" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072944": { "compartment": "compartment_70101", "id": "reaction_10072944", "reactome": "R-BTA-5654222", "name": "Activated FGFR3 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072941" ], "products": [ "species_29370", "species_10072911" ], "modifiers": [ [ "species_10072941", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10072946": { "compartment": "compartment_876", "id": "reaction_10072946", "reactome": "R-BTA-5654224", "name": "Activated FGFR3 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065265", "species_10061098" ], "products": [ "species_10072941" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_179838" ] }, "reaction_10073152": { "compartment": "compartment_70101", "id": "reaction_10073152", "reactome": "R-BTA-5654634", "name": "Activated FGFR3 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073138", "species_113592" ], "products": [ "species_29370", "species_10073149" ], "modifiers": [ [ "species_10073138", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073140": { "compartment": "compartment_70101", "id": "reaction_10073140", "reactome": "R-BTA-5654625", "name": "Activated FGFR3 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065265" ], "products": [ "species_10073138" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073156": { "compartment": "compartment_876", "id": "reaction_10073156", "reactome": "R-BTA-5654646", "name": "Activated FGFR3:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073149" ], "products": [ "species_10073154" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073159": { "compartment": "compartment_70101", "id": "reaction_10073159", "reactome": "R-BTA-5654647", "name": "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073154", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073234": { "compartment": "compartment_70101", "id": "reaction_10073234", "reactome": "R-BTA-5654709", "name": "FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065273", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073145": { "compartment": "compartment_876", "id": "reaction_10073145", "reactome": "R-BTA-5654631", "name": "Activated FGFR3 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073142", "species_113592" ], "products": [ "species_10065269", "species_29370" ], "modifiers": [ [ "species_10073142", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073019": { "compartment": "compartment_70101", "id": "reaction_10073019", "reactome": "R-BTA-5654413", "name": "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073016", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073147": { "compartment": "compartment_876", "id": "reaction_10073147", "reactome": "R-BTA-5654633", "name": "Activated FGFR3:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065267" ], "products": [ "species_10073142" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073021": { "compartment": "compartment_70101", "id": "reaction_10073021", "reactome": "R-BTA-5654416", "name": "Activated FGFR3:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065267" ], "products": [ "species_10073016" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10087376": { "compartment": "compartment_70101", "id": "reaction_10087376", "reactome": "R-BTA-8941628", "name": "Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065269", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073011": { "compartment": "compartment_876", "id": "reaction_10073011", "reactome": "R-BTA-5654408", "name": "Activated FGFR3 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073006" ], "products": [ "species_29370", "species_10065267" ], "modifiers": [ [ "species_10073006", "catalyst" ], [ "species_10073009", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073014": { "compartment": "compartment_70101", "id": "reaction_10073014", "reactome": "R-BTA-5654409", "name": "Activated FGFR3 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065265", "species_10072959" ], "products": [ "species_10073006" ], "modifiers": [], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10062984": { "compartment": "compartment_20699", "id": "reaction_10062984", "reactome": "R-BTA-2022860", "name": "NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062948", "species_741440" ], "products": [ "species_742343", "species_10062971" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063610": { "compartment": "compartment_20699", "id": "reaction_10063610", "reactome": "R-BTA-2076508", "name": "HS2ST1 sulfates IdoA at C2 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063045", "species_741440" ], "products": [ "species_742343", "species_10063068" ], "modifiers": [ [ "species_10063607", "catalyst" ] ], "additional_components": [ "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "ENSBTAT00000086518" ] }, "reaction_10063633": { "compartment": "compartment_20699", "id": "reaction_10063633", "reactome": "R-BTA-2076611", "name": "HS3STs sulfate GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063630", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VD21", "ENSBTAT00000085321", "E1B729", "ENSBTAT00000025630", "E1BKQ1", "ENSBTAT00000023123", "E1BNJ7", "ENSBTAT00000044024", "E1BP03", "ENSBTAT00000010350" ] }, "reaction_10063216": { "compartment": "compartment_17963", "id": "reaction_10063216", "reactome": "R-BTA-2024108", "name": "Some HSPGs are secreted to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063132" ], "products": [ "species_10063214" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452" ] }, "reaction_10063603": { "compartment": "compartment_20699", "id": "reaction_10063603", "reactome": "R-BTA-2076419", "name": "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063114" ], "products": [ "species_742343", "species_10063130" ], "modifiers": [ [ "species_10063600", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LS54", "ENSBTAT00000078465", "A0A3Q1LTK3", "ENSBTAT00000075020" ] }, "reaction_10063010": { "compartment": "compartment_20699", "id": "reaction_10063010", "reactome": "R-BTA-2022887", "name": "NDST1-4 N-deacetylates GlcNAc residues in heparan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_10063007" ], "products": [ "species_10062948", "species_2022890" ], "modifiers": [ [ "species_10062981", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "A8E4L2", "ENSBTAT00000080227" ] }, "reaction_10063586": { "compartment": "compartment_17963", "id": "reaction_10063586", "reactome": "R-BTA-2076383", "name": "HS3ST1 sulfates GlcN at C3 in heparan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063068" ], "products": [ "species_742343", "species_10063091" ], "modifiers": [ [ "species_10063583", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "Q0VCB5", "ENSBTAT00000009799" ] }, "reaction_10051589": { "compartment": "compartment_20699", "id": "reaction_10051589", "reactome": "R-BTA-744231", "name": "SLC35D2 exchanges UDP-sugars for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744229", "species_735698" ], "products": [ "species_109402", "species_744234" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "species_29410", "species_914003", "species_29410", "species_914003", "ENSBTAT00000026562" ] }, "reaction_10084090": { "compartment": "compartment_70101", "id": "reaction_10084090", "reactome": "R-BTA-8853429", "name": "PHLDA1 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084084" ], "products": [ "species_10084088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084096": { "compartment": "compartment_70101", "id": "reaction_10084096", "reactome": "R-BTA-8853444", "name": "AURKA phosphorylates PHLDA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084088" ], "products": [ "species_10084086", "species_29370", "species_10084093" ], "modifiers": [ [ "species_10084088", "catalyst" ] ], "additional_components": [ "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590", "ENSBTAT00000044590", "ENSBTAT00000011655", "F6Q0F9", "ENSBTAT00000011655", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10076112": { "compartment": "compartment_7660", "id": "reaction_10076112", "reactome": "R-BTA-5691381", "name": "MYSM1 deubiquitinates Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076107" ], "products": [ "species_10036828", "species_10076109" ], "modifiers": [ [ "species_10076107", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "A0A3Q1MUE2", "ENSBTAT00000080652" ] }, "reaction_10076119": { "compartment": "compartment_70101", "id": "reaction_10076119", "reactome": "R-BTA-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539" ], "products": [ "species_10039537" ], "modifiers": [ [ "species_10076116", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "ENSBTAT00000046166" ] }, "reaction_10089947": { "compartment": "compartment_876", "id": "reaction_10089947", "reactome": "R-BTA-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089943", "species_10073483" ], "products": [ "species_10089945" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LSX9", "ENSBTAT00000073284", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LV55", "ENSBTAT00000079495" ] }, "reaction_10092364": { "compartment": "compartment_876", "id": "reaction_10092364", "reactome": "R-BTA-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073483" ], "products": [ "species_10092362" ], "modifiers": [], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438" ] }, "reaction_10089937": { "compartment": "compartment_70101", "id": "reaction_10089937", "reactome": "R-BTA-9013109", "name": "RHOC GEFs activate RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10089932" ], "products": [ "species_29420", "species_10073483" ], "modifiers": [ [ "species_10089934", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LFQ5", "ENSBTAT00000066417", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LQ45", "ENSBTAT00000078928", "F1N2G5", "ENSBTAT00000002373", "F1MB21", "ENSBTAT00000017829" ] }, "reaction_10089952": { "compartment": "compartment_876", "id": "reaction_10089952", "reactome": "R-BTA-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073483" ], "products": [ "species_29372", "species_10089932" ], "modifiers": [ [ "species_10089949", "catalyst" ] ], "additional_components": [ "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29420", "E1BM23", "ENSBTAT00000038690", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092392": { "compartment": "compartment_12045", "id": "reaction_10092392", "reactome": "R-BTA-9714691", "name": "RAC3 binds ER effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092388", "species_10092384" ], "products": [ "species_10092390" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090330": { "compartment": "compartment_876", "id": "reaction_10090330", "reactome": "R-BTA-9018804", "name": "RAC3 GEFs activate RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090323" ], "products": [ "species_10090325", "species_29420" ], "modifiers": [ [ "species_10090327", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "A5PK69", "ENSBTAT00000079280", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10092394": { "compartment": "compartment_876", "id": "reaction_10092394", "reactome": "R-BTA-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090325" ], "products": [ "species_10092388" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29438" ] }, "reaction_10090349": { "compartment": "compartment_876", "id": "reaction_10090349", "reactome": "R-BTA-9018807", "name": "RAC3 GDIs block activation of RAC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090341", "species_10090323" ], "products": [ "species_10090347" ], "modifiers": [], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29420", "species_29420", "A5PK69", "ENSBTAT00000079280" ] }, "reaction_10090339": { "compartment": "compartment_876", "id": "reaction_10090339", "reactome": "R-BTA-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090325" ], "products": [ "species_29372", "species_10090323" ], "modifiers": [ [ "species_10090336", "catalyst" ] ], "additional_components": [ "A5PK69", "ENSBTAT00000079280", "species_29438", "A5PK69", "ENSBTAT00000079280", "species_29420", "F1N6V1", "ENSBTAT00000003400", "A4IF90", "ENSBTAT00000061453", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10089930": { "compartment": "compartment_876", "id": "reaction_10089930", "reactome": "R-BTA-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089926", "species_10037315" ], "products": [ "species_10089928" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LV55", "ENSBTAT00000079495", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BMN2", "ENSBTAT00000061079", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LM61", "ENSBTAT00000075730", "A0A3Q1LJH7", "ENSBTAT00000073587", "G3X696", "ENSBTAT00000001346", "F1MBT6", "ENSBTAT00000046371" ] }, "reaction_10089149": { "compartment": "compartment_70101", "id": "reaction_10089149", "reactome": "R-BTA-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037315" ], "products": [ "species_29372", "species_10037313" ], "modifiers": [ [ "species_10089146", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29420", "Q08DB1", "ENSBTAT00000039899", "F1MGB9", "ENSBTAT00000052139", "A0A3Q1M2Q1", "ENSBTAT00000076617", "E1BI70", "ENSBTAT00000027682", "F1MYQ4", "ENSBTAT00000011665", "G3MXE8", "ENSBTAT00000066138", "E1BIM3", "ENSBTAT00000035838", "E1BM23", "ENSBTAT00000038690", "F1MWY5", "ENSBTAT00000023764", "F1N6V1", "ENSBTAT00000003400", "A4FV18", "ENSBTAT00000020147", "A0A3Q1LWV5", "ENSBTAT00000075058", "A0A3Q1LGT5", "ENSBTAT00000075956" ] }, "reaction_10089888": { "compartment": "compartment_12045", "id": "reaction_10089888", "reactome": "R-BTA-9013004", "name": "RHOA binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089862", "species_10089884" ], "products": [ "species_10089886" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089011": { "compartment": "compartment_70101", "id": "reaction_10089011", "reactome": "R-BTA-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10089008", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "A0A3Q1MRV3", "ENSBTAT00000083879", "E1BH51", "ENSBTAT00000005514", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1M8D9", "ENSBTAT00000071999", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LNE2", "ENSBTAT00000077218", "E1BDY4", "ENSBTAT00000082024", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1N6F4", "ENSBTAT00000072165", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LFQ5", "ENSBTAT00000066417", "Q08DA6", "ENSBTAT00000011773", "A0A3Q1LKT3", "ENSBTAT00000074225", "A0A3Q1MA88", "ENSBTAT00000069507", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10089890": { "compartment": "compartment_876", "id": "reaction_10089890", "reactome": "R-BTA-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315" ], "products": [ "species_10089862" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10089860": { "compartment": "compartment_70101", "id": "reaction_10089860", "reactome": "R-BTA-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313", "species_10089854" ], "products": [ "species_10089858" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "ENSBTAT00000007933", "A0A452DIS6", "ENSBTAT00000007933", "P61585", "ENSBTAT00000005600", "species_29420" ] }, "reaction_10090125": { "compartment": "compartment_70101", "id": "reaction_10090125", "reactome": "R-BTA-9014456", "name": "GDIs block activation of RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089854", "species_10090093" ], "products": [ "species_10090123" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007933", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29420", "A0A452DIS6", "ENSBTAT00000007933" ] }, "reaction_10090145": { "compartment": "compartment_12045", "id": "reaction_10090145", "reactome": "R-BTA-9014467", "name": "RHOG binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090117", "species_10090141" ], "products": [ "species_10090143" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090115": { "compartment": "compartment_876", "id": "reaction_10090115", "reactome": "R-BTA-9014449", "name": "RHOG binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090111", "species_10037305" ], "products": [ "species_10090113" ], "modifiers": [], "additional_components": [ "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LX25", "ENSBTAT00000069555", "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1MT94", "ENSBTAT00000085032", "F1MTR1", "ENSBTAT00000001190", "A0A3Q1NNR4", "ENSBTAT00000083570" ] }, "reaction_10090098": { "compartment": "compartment_876", "id": "reaction_10090098", "reactome": "R-BTA-9014433", "name": "RHOG GEFs activate RHOG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090093" ], "products": [ "species_29420", "species_10037305" ], "modifiers": [ [ "species_10090095", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMI2", "ENSBTAT00000000453", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1MRV3", "ENSBTAT00000083879", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090103": { "compartment": "compartment_876", "id": "reaction_10090103", "reactome": "R-BTA-9014434", "name": "RHOG GAPs stimulate RHOG GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037305" ], "products": [ "species_29372", "species_10090093" ], "modifiers": [ [ "species_10090100", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10090119": { "compartment": "compartment_876", "id": "reaction_10090119", "reactome": "R-BTA-9014454", "name": "RHOG translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037305" ], "products": [ "species_10090117" ], "modifiers": [], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "species_29438", "Q1RMI2", "ENSBTAT00000000453", "species_29438" ] }, "reaction_10090089": { "compartment": "compartment_876", "id": "reaction_10090089", "reactome": "R-BTA-9014420", "name": "RAC2 translocates to the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10073712" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090091": { "compartment": "compartment_1222693", "id": "reaction_10090091", "reactome": "R-BTA-9014424", "name": "RAC2 binds effectors at the phagocytic vesicle membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090077": { "compartment": "compartment_70101", "id": "reaction_10090077", "reactome": "R-BTA-9014294", "name": "RAC2 binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299", "species_10090073" ], "products": [ "species_10090075" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "A0A3Q1MFB9", "ENSBTAT00000080368", "Q08E52", "ENSBTAT00000080749", "Q17QZ0", "ENSBTAT00000086158", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092380": { "compartment": "compartment_12045", "id": "reaction_10092380", "reactome": "R-BTA-9714481", "name": "RAC2 binds effectors at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092374", "species_10092376" ], "products": [ "species_10092378" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10092382": { "compartment": "compartment_876", "id": "reaction_10092382", "reactome": "R-BTA-9714483", "name": "RAC2 translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092374" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090082": { "compartment": "compartment_70101", "id": "reaction_10090082", "reactome": "R-BTA-9014295", "name": "RAC2 GAPs stimulate RAC2 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10037299" ], "products": [ "species_29372", "species_10090033" ], "modifiers": [ [ "species_10090079", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092370": { "compartment": "compartment_876", "id": "reaction_10092370", "reactome": "R-BTA-9714480", "name": "RAC2 translocates to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037299" ], "products": [ "species_10092368" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10090087": { "compartment": "compartment_70101", "id": "reaction_10090087", "reactome": "R-BTA-9014296", "name": "RAC2 GEFs activate RAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090033" ], "products": [ "species_29420", "species_10037299" ], "modifiers": [ [ "species_10090084", "catalyst" ] ], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29420", "Q9TU25", "ENSBTAT00000014666", "species_29438", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1LWX5", "ENSBTAT00000081739", "A0A3Q1M4M7", "ENSBTAT00000071096", "A0A3Q1MKN5", "ENSBTAT00000080659", "F1MLS2", "ENSBTAT00000061086" ] }, "reaction_10090203": { "compartment": "compartment_876", "id": "reaction_10090203", "reactome": "R-BTA-9017491", "name": "RHOJ GEFs activate RHOJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10090193" ], "products": [ "species_29420", "species_10090191" ], "modifiers": [ [ "species_10090200", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29420", "A4FV20", "ENSBTAT00000022858", "species_29438", "E1BNA6", "ENSBTAT00000002840" ] }, "reaction_10090198": { "compartment": "compartment_876", "id": "reaction_10090198", "reactome": "R-BTA-9017488", "name": "RHOJ GAPs stimulate RHOJ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090191" ], "products": [ "species_29372", "species_10090193" ], "modifiers": [ [ "species_10090195", "catalyst" ] ], "additional_components": [ "A4FV20", "ENSBTAT00000022858", "species_29438", "A4FV20", "ENSBTAT00000022858", "species_29420", "F6RWK1", "ENSBTAT00000043933", "E1B801", "ENSBTAT00000085833", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10091994": { "compartment": "compartment_70101", "id": "reaction_10091994", "reactome": "R-BTA-9696266", "name": "RND2 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091990", "species_10091948" ], "products": [ "species_10091992" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393", "F1MUP6", "ENSBTAT00000009719", "species_29438", "F1MUP6", "ENSBTAT00000009719", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1B7I9", "ENSBTAT00000025495", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1LPM3", "ENSBTAT00000068488", "F1N4C5", "ENSBTAT00000002375", "A0A3Q1M6F8", "ENSBTAT00000077393" ] }, "reaction_10092022": { "compartment": "compartment_70101", "id": "reaction_10092022", "reactome": "R-BTA-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091946" ], "products": [ "species_10091948" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009719", "F1MUP6", "ENSBTAT00000009719", "species_29438" ] }, "reaction_10091832": { "compartment": "compartment_876", "id": "reaction_10091832", "reactome": "R-BTA-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091827" ], "products": [ "species_29420", "species_10091829" ], "modifiers": [ [ "species_10091827", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29420", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420" ] }, "reaction_10091864": { "compartment": "compartment_876", "id": "reaction_10091864", "reactome": "R-BTA-9693125", "name": "RHOF binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091860", "species_10091829" ], "products": [ "species_10091862" ], "modifiers": [], "additional_components": [ "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29438", "A0A452DIN5", "ENSBTAT00000020331", "A0A3Q1LUD9", "ENSBTAT00000083004", "F1MXR0", "ENSBTAT00000030984", "F1MFC6", "ENSBTAT00000072393" ] }, "reaction_10091921": { "compartment": "compartment_876", "id": "reaction_10091921", "reactome": "R-BTA-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10091829" ], "products": [ "species_29372", "species_10091827" ], "modifiers": [ [ "species_10091918", "catalyst" ] ], "additional_components": [ "Q3SZA1", "ENSBTAT00000046161", "species_29438", "Q3SZA1", "ENSBTAT00000046161", "species_29420", "F6RWK1", "ENSBTAT00000043933" ] }, "reaction_10090266": { "compartment": "compartment_70101", "id": "reaction_10090266", "reactome": "R-BTA-9018746", "name": "RHOQ binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090262", "species_10090239" ], "products": [ "species_10090264" ], "modifiers": [], "additional_components": [ "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391", "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438", "A0A3Q1MPX4", "ENSBTAT00000082212", "F1MS60", "ENSBTAT00000012813", "Q2KI46", "ENSBTAT00000032505", "Q08E52", "ENSBTAT00000080749", "A2VDU0", "ENSBTAT00000018391" ] }, "reaction_10090369": { "compartment": "compartment_876", "id": "reaction_10090369", "reactome": "R-BTA-9018836", "name": "RHOQ translocates to the Golgi-associated vesicle membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090239" ], "products": [ "species_10090367" ], "modifiers": [], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29438" ] }, "reaction_10090246": { "compartment": "compartment_70101", "id": "reaction_10090246", "reactome": "R-BTA-9018745", "name": "RHOQ GAPs stimulate RHOQ GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10090239" ], "products": [ "species_29372", "species_10090241" ], "modifiers": [ [ "species_10090243", "catalyst" ] ], "additional_components": [ "F1MK42", "ENSBTAT00000018269", "species_29438", "F1MK42", "ENSBTAT00000018269", "species_29420", "F6RWK1", "ENSBTAT00000043933", "A0A3Q1LWV5", "ENSBTAT00000075058" ] }, "reaction_10092002": { "compartment": "compartment_70101", "id": "reaction_10092002", "reactome": "R-BTA-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091998" ], "products": [ "species_10092000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045869", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10092020": { "compartment": "compartment_70101", "id": "reaction_10092020", "reactome": "R-BTA-9696268", "name": "RND3 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092016", "species_10092000" ], "products": [ "species_10092018" ], "modifiers": [], "additional_components": [ "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438", "E1BM23", "ENSBTAT00000038690", "E1BLB2", "ENSBTAT00000010671", "A0A3Q1M6F8", "ENSBTAT00000077393", "A5PKJ7", "ENSBTAT00000045869", "species_29438" ] }, "reaction_10063353": { "compartment": "compartment_70101", "id": "reaction_10063353", "reactome": "R-BTA-2029460", "name": "PAK1 phosphorylates LIMK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047644", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "ENSBTAT00000080749" ] }, "reaction_10073755": { "compartment": "compartment_70101", "id": "reaction_10073755", "reactome": "R-BTA-5668731", "name": "NOX3 complex:RAC1:GTP generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_352327" ], "products": [ "species_70106", "species_29366", "species_3299686" ], "modifiers": [ [ "species_10073752", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "E1BFF3", "ENSBTAT00000018021", "species_29438" ] }, "reaction_10091180": { "compartment": "compartment_70101", "id": "reaction_10091180", "reactome": "R-BTA-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091177" ], "products": [ "species_29370", "species_10091162" ], "modifiers": [ [ "species_10040565", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10091169": { "compartment": "compartment_70101", "id": "reaction_10091169", "reactome": "R-BTA-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091164", "species_10091162" ], "products": [ "species_10091166" ], "modifiers": [ [ "species_10091164", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022592", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "ENSBTAT00000022592" ] }, "reaction_10073731": { "compartment": "compartment_263698", "id": "reaction_10073731", "reactome": "R-BTA-5668629", "name": "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236709", "species_29364" ], "products": [ "species_70106", "species_2000345", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ], [ "species_10073729", "catalyst" ], [ "species_1629751", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438", "species_74016", "P28782", "ENSBTAT00000066555", "species_140356", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10073716": { "compartment": "compartment_1222693", "id": "reaction_10073716", "reactome": "R-BTA-5668605", "name": "RAC2:GTP binds NOX2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073712", "species_10057001" ], "products": [ "species_10073714" ], "modifiers": [], "additional_components": [ "Q9TU25", "ENSBTAT00000014666", "species_29438", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10091175": { "compartment": "compartment_70101", "id": "reaction_10091175", "reactome": "R-BTA-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091166" ], "products": [ "species_10091173", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10063374": { "compartment": "compartment_70101", "id": "reaction_10063374", "reactome": "R-BTA-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043441", "species_10063372" ], "products": [ "species_10061166" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_29370", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "species_113592", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q148J6", "ENSBTAT00000070990", "Q3MHR7", "ENSBTAT00000070600", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1NMB5", "ENSBTAT00000082840", "Q58CQ2", "ENSBTAT00000064158", "P63258", "ENSBTAT00000008132" ] }, "reaction_10073577": { "compartment": "compartment_70101", "id": "reaction_10073577", "reactome": "R-BTA-5667008", "name": "RHOA:GTP binds RHPN1 or RHPN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073573", "species_10037315" ], "products": [ "species_10073575" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073587", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LJH7", "ENSBTAT00000073587" ] }, "reaction_10072515": { "compartment": "compartment_70101", "id": "reaction_10072515", "reactome": "R-BTA-5625959", "name": "Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072511", "species_10072505" ], "products": [ "species_10072513" ], "modifiers": [], "additional_components": [ "A0A3Q1LVS2", "ENSBTAT00000069650", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073842": { "compartment": "compartment_70101", "id": "reaction_10073842", "reactome": "R-BTA-5672083", "name": "KTN1 binds Kinesin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072513", "species_10055513" ], "products": [ "species_10073840" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "P61585", "ENSBTAT00000005600", "Q1RMI2", "ENSBTAT00000000453", "species_29438", "A0A3Q1LVS2", "ENSBTAT00000069650" ] }, "reaction_10073806": { "compartment": "compartment_876", "id": "reaction_10073806", "reactome": "R-BTA-5671993", "name": "CIT-3 binds DLG4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073802", "species_10050472" ], "products": [ "species_10073804" ], "modifiers": [], "additional_components": [ "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "ENSBTAT00000003326", "F1MM66", "ENSBTAT00000003326", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600" ] }, "reaction_10073796": { "compartment": "compartment_70101", "id": "reaction_10073796", "reactome": "R-BTA-5671970", "name": "Activated CIT binds KIF14 and PRC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073792", "species_10073788", "species_10073784" ], "products": [ "species_10073794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076885", "ENSBTAT00000029161", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "A0A3Q1LV55", "ENSBTAT00000079495", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "P61585", "ENSBTAT00000005600", "G5E5S3", "ENSBTAT00000029161", "Q2T9P1", "ENSBTAT00000076885" ] }, "reaction_10073561": { "compartment": "compartment_70101", "id": "reaction_10073561", "reactome": "R-BTA-5666001", "name": "Profilin:G-actin binds MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541", "species_10043459" ], "products": [ "species_10073543" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073503": { "compartment": "compartment_70101", "id": "reaction_10073503", "reactome": "R-BTA-5665761", "name": "FMNL3 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073499", "species_10073483" ], "products": [ "species_10073501" ], "modifiers": [], "additional_components": [ "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075" ] }, "reaction_10073525": { "compartment": "compartment_876", "id": "reaction_10073525", "reactome": "R-BTA-5665802", "name": "SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073521", "species_10073517" ], "products": [ "species_10073523" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068363", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1M6W5", "ENSBTAT00000078036", "species_29438", "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LMM5", "ENSBTAT00000068363" ] }, "reaction_10073493": { "compartment": "compartment_876", "id": "reaction_10073493", "reactome": "R-BTA-5665748", "name": "FMNL2 binds RHOC:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073489", "species_10073483" ], "products": [ "species_10073491" ], "modifiers": [], "additional_components": [ "A0A3Q1LSX9", "ENSBTAT00000073284", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "A0A3Q1LSX9", "ENSBTAT00000073284" ] }, "reaction_10073557": { "compartment": "compartment_7660", "id": "reaction_10073557", "reactome": "R-BTA-5665998", "name": "MKL1 binds SRF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068967", "species_10073553" ], "products": [ "species_10073555" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000016981", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073559": { "compartment": "compartment_70101", "id": "reaction_10073559", "reactome": "R-BTA-5665999", "name": "MKL1 translocates from cytosol to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073541" ], "products": [ "species_10068967" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070929", "ENSBTAT00000070929" ] }, "reaction_10073547": { "compartment": "compartment_70101", "id": "reaction_10073547", "reactome": "R-BTA-5665982", "name": "RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073543", "species_10073539", "species_10073537" ], "products": [ "species_10073541", "species_10073545" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "A0A3Q1LLJ2", "ENSBTAT00000070929", "A0A3Q1MSR1", "ENSBTAT00000069763", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000070929", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1MSR1", "ENSBTAT00000069763", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068939": { "compartment": "compartment_70101", "id": "reaction_10068939", "reactome": "R-BTA-3858495", "name": "DAAM1 recruits GTP-bound RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068935", "species_10068931" ], "products": [ "species_10068937" ], "modifiers": [], "additional_components": [ "species_29926", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "species_29926", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073549": { "compartment": "compartment_70101", "id": "reaction_10073549", "reactome": "R-BTA-5665989", "name": "DIAPH1 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037315", "species_10073535" ], "products": [ "species_10073537" ], "modifiers": [], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LUD9", "ENSBTAT00000083004", "P61585", "ENSBTAT00000005600", "species_29438" ] }, "reaction_10073569": { "compartment": "compartment_7660", "id": "reaction_10073569", "reactome": "R-BTA-5666008", "name": "SCAI binds SRF:MKL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073555", "species_10073565" ], "products": [ "species_10073567" ], "modifiers": [], "additional_components": [ "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929", "ENSBTAT00000072829", "A0A3Q1M5I0", "ENSBTAT00000072829", "E1BJP4", "ENSBTAT00000016981", "A0A3Q1LLJ2", "ENSBTAT00000070929" ] }, "reaction_10073507": { "compartment": "compartment_70101", "id": "reaction_10073507", "reactome": "R-BTA-5665767", "name": "Activated FMNL3 binds G-actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043459", "species_10073501" ], "products": [ "species_10073505" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "Q1RMJ6", "ENSBTAT00000018998", "species_29438", "E1B718", "ENSBTAT00000022075", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10043461": { "compartment": "compartment_70101", "id": "reaction_10043461", "reactome": "R-BTA-203070", "name": "Association of profilin with monomeric actin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043457", "species_10043441" ], "products": [ "species_10043459" ], "modifiers": [], "additional_components": [ "P63258", "ENSBTAT00000008132", "species_113592", "P63258", "ENSBTAT00000008132", "species_113592" ] }, "reaction_10068933": { "compartment": "compartment_70101", "id": "reaction_10068933", "reactome": "R-BTA-3858489", "name": "ppDVL binds DAAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068929", "species_10068927" ], "products": [ "species_10068931" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "ENSBTAT00000075877", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10092203": { "compartment": "compartment_263163", "id": "reaction_10092203", "reactome": "R-BTA-9706390", "name": "RHOBTB3 binds interacting proteins at trans-Golgi network", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092199", "species_10083329" ], "products": [ "species_10092201" ], "modifiers": [], "additional_components": [ "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q08DW1", "ENSBTAT00000014511", "Q3SX32", "ENSBTAT00000015669", "Q0VCB4", "ENSBTAT00000026403", "G3N2Y1", "ENSBTAT00000064452", "E1BL53", "ENSBTAT00000030804", "E1BD86", "ENSBTAT00000011575" ] }, "reaction_10092205": { "compartment": "compartment_263163", "id": "reaction_10092205", "reactome": "R-BTA-9706393", "name": "RHOBTB3 binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083327" ], "products": [ "species_10083329" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080085", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10092208": { "compartment": "compartment_263163", "id": "reaction_10092208", "reactome": "R-BTA-9706399", "name": "RHOBTB3 hydrolyzes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083329" ], "products": [ "species_10083335", "species_29372" ], "modifiers": [ [ "species_10083329", "catalyst" ] ], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10071262": { "compartment": "compartment_13231", "id": "reaction_10071262", "reactome": "R-BTA-5252001", "name": "ATP1B4 binds SNW1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044442", "species_10071258" ], "products": [ "species_10071260" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010697", "ENSBTAT00000011740", "A7MB71", "ENSBTAT00000011740", "Q1JQE0", "ENSBTAT00000010697" ] }, "reaction_10064933": { "compartment": "compartment_7660", "id": "reaction_10064933", "reactome": "R-BTA-2186767", "name": "Degradation of ubiquitinated SKI/SKIL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064931" ], "products": [], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N727", "ENSBTAT00000060953", "E1BJ37", "ENSBTAT00000005438" ] }, "reaction_10043311": { "compartment": "compartment_876", "id": "reaction_10043311", "reactome": "R-BTA-202604", "name": "Formation of a heteromeric BMP receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042988", "species_10043000" ], "products": [ "species_10043002" ], "modifiers": [], "additional_components": [ "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1MGJ6", "ENSBTAT00000077971", "A0A3Q1LP90", "ENSBTAT00000073964", "A0A3Q1LSA1", "ENSBTAT00000078787", "F1MCE7", "ENSBTAT00000000282" ] }, "reaction_10084542": { "compartment": "compartment_984", "id": "reaction_10084542", "reactome": "R-BTA-8858346", "name": "AMHR2 binds AMH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084532", "species_10084538" ], "products": [ "species_10084540" ], "modifiers": [], "additional_components": [ "F1MZL1", "ENSBTAT00000019912", "E1BHR7", "ENSBTAT00000024657", "E1BHR7", "ENSBTAT00000024657", "F1MZL1", "ENSBTAT00000019912" ] }, "reaction_10042976": { "compartment": "compartment_70101", "id": "reaction_10042976", "reactome": "R-BTA-201445", "name": "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042969" ], "products": [], "modifiers": [ [ "species_10042973", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072746", "ENSBTAT00000043725" ] }, "reaction_10056354": { "compartment": "compartment_876", "id": "reaction_10056354", "reactome": "R-BTA-1181149", "name": "ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056341", "species_113592" ], "products": [ "species_29370", "species_10056351" ], "modifiers": [ [ "species_10056341", "catalyst" ] ], "additional_components": [ "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665", "F1MSQ2", "ENSBTAT00000046665", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10056356": { "compartment": "compartment_876", "id": "reaction_10056356", "reactome": "R-BTA-1181153", "name": "Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056339", "species_10042992", "species_10045724" ], "products": [ "species_10056341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046665", "ENSBTAT00000077971", "P07995", "ENSBTAT00000066382", "P07995", "ENSBTAT00000066382", "A0A3Q1MGJ6", "ENSBTAT00000077971", "F1MSQ2", "ENSBTAT00000046665" ] }, "reaction_10068704": { "compartment": "compartment_70101", "id": "reaction_10068704", "reactome": "R-BTA-3772434", "name": "Phosphorylated DVL recruits PIP5K1B to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060420", "species_10043116" ], "products": [ "species_10068702" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080996", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10068707": { "compartment": "compartment_70101", "id": "reaction_10068707", "reactome": "R-BTA-3772436", "name": "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10068702", "catalyst" ] ], "additional_components": [ "F1MMW6", "ENSBTAT00000025757", "F1N6M9", "ENSBTAT00000014152", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10067694": { "compartment": "compartment_7660", "id": "reaction_10067694", "reactome": "R-BTA-3322429", "name": "XIAP monoubiquinates TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10067672" ], "products": [ "species_10067691" ], "modifiers": [ [ "species_10067672", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067696": { "compartment": "compartment_7660", "id": "reaction_10067696", "reactome": "R-BTA-3322431", "name": "XIAP binds TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067670", "species_10067668" ], "products": [ "species_10067672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "G3MWG5", "ENSBTAT00000067597" ] }, "reaction_10067698": { "compartment": "compartment_7660", "id": "reaction_10067698", "reactome": "R-BTA-3322434", "name": "XIAP dissociates from ub-TLE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067691" ], "products": [ "species_10067670", "species_10067689" ], "modifiers": [], "additional_components": [ "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "G3MWG5", "ENSBTAT00000067597", "ENSBTAT00000067597", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289" ] }, "reaction_10068095": { "compartment": "compartment_70101", "id": "reaction_10068095", "reactome": "R-BTA-3640872", "name": "USP34 deubiquitinates AXIN1,AXIN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068083" ], "products": [ "species_10068071", "species_10033408" ], "modifiers": [ [ "species_10068092", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000078346" ] }, "reaction_10068073": { "compartment": "compartment_70101", "id": "reaction_10068073", "reactome": "R-BTA-3640844", "name": "RNF146 binds RibC-AXIN:TNKS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068054", "species_10068069" ], "products": [ "species_10068071" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10068088": { "compartment": "compartment_70101", "id": "reaction_10068088", "reactome": "R-BTA-3640862", "name": "Tankyrase binds AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041524", "species_10068067" ], "products": [ "species_10068075" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068078": { "compartment": "compartment_70101", "id": "reaction_10068078", "reactome": "R-BTA-3640858", "name": "Tankyrase ADP-ribosylates AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068075", "species_29360" ], "products": [ "species_197277", "species_10068069" ], "modifiers": [ [ "species_10068075", "catalyst" ] ], "additional_components": [ "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "M5FK80", "ENSBTAT00000087508" ] }, "reaction_10068086": { "compartment": "compartment_70101", "id": "reaction_10068086", "reactome": "R-BTA-3640861", "name": "RNF146 ubiquitinates ADP-ribosylated AXIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068071", "species_10033408" ], "products": [ "species_10068083" ], "modifiers": [ [ "species_10068071", "catalyst" ] ], "additional_components": [ "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099", "M5FK80", "ENSBTAT00000087508", "A0A3Q1M230", "ENSBTAT00000085809", "E1B8R5", "ENSBTAT00000001917", "Q3T139", "ENSBTAT00000038099" ] }, "reaction_10067879": { "compartment": "compartment_7660", "id": "reaction_10067879", "reactome": "R-BTA-3364026", "name": "SET1 complex trimethylates H3K4 at the MYC gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10067848" ], "products": [ "species_77502", "species_10067852" ], "modifiers": [ [ "species_10067876", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "F1MHP8", "ENSBTAT00000012057", "E1BEP4", "ENSBTAT00000001294", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A4FUE3", "ENSBTAT00000021204", "E1BPF3", "ENSBTAT00000080372", "A0A3Q1M6V2", "ENSBTAT00000067448", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10071330": { "compartment": "compartment_984", "id": "reaction_10071330", "reactome": "R-BTA-5323545", "name": "Canonical WNT signaling through the atypical receptor RYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071326", "species_10071324" ], "products": [ "species_10071328" ], "modifiers": [], "additional_components": [ "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000071795", "A0A3Q1N0Q2", "ENSBTAT00000071795", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10069645": { "compartment": "compartment_876", "id": "reaction_10069645", "reactome": "R-BTA-4641205", "name": "RSPO:LGR binds ZNRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069631", "species_10069641" ], "products": [ "species_10069643" ], "modifiers": [], "additional_components": [ "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069647": { "compartment": "compartment_876", "id": "reaction_10069647", "reactome": "R-BTA-4641206", "name": "RSPOs bind LGRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069615", "species_10069629" ], "products": [ "species_10069631" ], "modifiers": [], "additional_components": [ "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069664": { "compartment": "compartment_876", "id": "reaction_10069664", "reactome": "R-BTA-4641246", "name": "ZNRF3 autoubiquitinates to promote its internalization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10069643" ], "products": [ "species_10069661" ], "modifiers": [ [ "species_10069643", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "E1BNT4", "ENSBTAT00000026797", "A0A3Q1MCX1", "ENSBTAT00000083590", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1MCX1", "ENSBTAT00000083590", "E1BNT4", "ENSBTAT00000026797", "F1MH47", "ENSBTAT00000029170", "F1ME23", "ENSBTAT00000078037", "F6RLD1", "ENSBTAT00000018083", "A0A452DIK6", "ENSBTAT00000017631", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10069607": { "compartment": "compartment_70101", "id": "reaction_10069607", "reactome": "R-BTA-4641147", "name": "DACT1 binds DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069603", "species_10043149" ], "products": [ "species_10069605" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025871", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "F1MP88", "ENSBTAT00000025871" ] }, "reaction_10068923": { "compartment": "compartment_876", "id": "reaction_10068923", "reactome": "R-BTA-3858482", "name": "DVL is recruited to the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068919", "species_10068917" ], "products": [ "species_10068921" ], "modifiers": [], "additional_components": [ "A0A3Q1MSZ4", "ENSBTAT00000078307", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A7MB15", "ENSBTAT00000002720", "F1N4K7", "ENSBTAT00000002946", "E1BEN9", "ENSBTAT00000020414", "F1N4C0", "ENSBTAT00000014355", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069896": { "compartment": "compartment_876", "id": "reaction_10069896", "reactome": "R-BTA-5140741", "name": "WNT5A binds FZD and ROR receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069892", "species_10067196" ], "products": [ "species_10069894" ], "modifiers": [], "additional_components": [ "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "E1BC57", "ENSBTAT00000061589", "G3N2W8", "ENSBTAT00000027434", "F1MGM1", "ENSBTAT00000027911" ] }, "reaction_10069882": { "compartment": "compartment_876", "id": "reaction_10069882", "reactome": "R-BTA-5138441", "name": "WNT5A-FZD4 recruits DVL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069874", "species_10043149" ], "products": [ "species_10069878" ], "modifiers": [], "additional_components": [ "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "ENSBTAT00000078307", "A0A3Q1MSZ4", "ENSBTAT00000078307", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069876": { "compartment": "compartment_876", "id": "reaction_10069876", "reactome": "R-BTA-5099899", "name": "WNT5A binds FZD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069862", "species_10067196" ], "products": [ "species_10069874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061370", "ENSBTAT00000026930", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370" ] }, "reaction_10069299": { "compartment": "compartment_70101", "id": "reaction_10069299", "reactome": "R-BTA-3965450", "name": "DAAM1 recruits PFN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068931", "species_10043451" ], "products": [ "species_10069297" ], "modifiers": [], "additional_components": [ "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "P02584", "ENSBTAT00000024367", "E1BHJ0", "ENSBTAT00000024367", "A0A3Q1LHF1", "ENSBTAT00000075877", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10069448": { "compartment": "compartment_70101", "id": "reaction_10069448", "reactome": "R-BTA-4332358", "name": "Dissociation of CaM and CAMK2 autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069445", "species_113592" ], "products": [ "species_29370", "species_10069441", "species_10037002" ], "modifiers": [ [ "species_10069445", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069456": { "compartment": "compartment_70101", "id": "reaction_10069456", "reactome": "R-BTA-4332359", "name": "Active calmodulin binds CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069452", "species_10037002" ], "products": [ "species_10069454" ], "modifiers": [], "additional_components": [ "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10069459": { "compartment": "compartment_70101", "id": "reaction_10069459", "reactome": "R-BTA-4332363", "name": "Autophosphorylation and activation of CAMK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069454" ], "products": [ "species_10069445", "species_29370" ], "modifiers": [ [ "species_10069454", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084" ] }, "reaction_10067128": { "compartment": "compartment_20699", "id": "reaction_10067128", "reactome": "R-BTA-3247840", "name": "WLS binds WNT ligands in the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067122", "species_10066990" ], "products": [ "species_10067126" ], "modifiers": [], "additional_components": [ "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067200": { "compartment": "compartment_984", "id": "reaction_10067200", "reactome": "R-BTA-3247843", "name": "secretion of WNT ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10067198", "species_10067130" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "A0A3Q1M1A0", "ENSBTAT00000086580", "A6H6X8", "ENSBTAT00000018985", "E1BDG5", "ENSBTAT00000026930", "E1BKL2", "ENSBTAT00000035270", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "F1MHG3", "ENSBTAT00000017163", "A0A3Q1MPF5", "ENSBTAT00000081055", "A4D7S0", "ENSBTAT00000010650", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MEW8", "ENSBTAT00000012148", "F1MK64", "ENSBTAT00000020402", "F1N4C0", "ENSBTAT00000014355", "ENSBTAT00000077814" ] }, "reaction_10067202": { "compartment": "compartment_20699", "id": "reaction_10067202", "reactome": "R-BTA-3247844", "name": "WNT ligands traffic to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067126" ], "products": [ "species_10067168" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592" ] }, "reaction_10066994": { "compartment": "compartment_20699", "id": "reaction_10066994", "reactome": "R-BTA-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066988" ], "products": [ "species_10066992" ], "modifiers": [], "additional_components": [ "Q1RMH8", "ENSBTAT00000025026", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q1RMH8", "ENSBTAT00000025026", "A0A3Q1MGH5", "ENSBTAT00000077814", "Q0VD53", "ENSBTAT00000022455", "Q2HJG5", "ENSBTAT00000003239" ] }, "reaction_10068837": { "compartment": "compartment_383505", "id": "reaction_10068837", "reactome": "R-BTA-3781941", "name": "WNTs are secreted in exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068795" ], "products": [ "species_10068835" ], "modifiers": [], "additional_components": [ "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814", "A0A3Q1MGH5", "ENSBTAT00000077814", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978" ] }, "reaction_10067124": { "compartment": "compartment_17963", "id": "reaction_10067124", "reactome": "R-BTA-3247837", "name": "WNT ligands traffic to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067086" ], "products": [ "species_10067122" ], "modifiers": [], "additional_components": [ "F1N6L8", "ENSBTAT00000002188", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1LVG1", "ENSBTAT00000068978", "A0A3Q1MQ82", "ENSBTAT00000083229", "A0A3Q1MJR6", "ENSBTAT00000085976", "F1MN70", "ENSBTAT00000018592", "E1BEN9", "ENSBTAT00000020414", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930" ] }, "reaction_10067204": { "compartment": "compartment_171062", "id": "reaction_10067204", "reactome": "R-BTA-3247847", "name": "WLS is endocytosed to the early endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067130" ], "products": [ "species_10066982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077814", "ENSBTAT00000077814" ] }, "reaction_10068839": { "compartment": "compartment_876", "id": "reaction_10068839", "reactome": "R-BTA-3781943", "name": "WLS:WNT complex is internalized for maturation into exosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067168" ], "products": [ "species_10068795" ], "modifiers": [], "additional_components": [ "A0A3Q1MGH5", "ENSBTAT00000077814", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N5R1", "ENSBTAT00000021312", "A0A3Q1MJR6", "ENSBTAT00000085976", "E1BDG5", "ENSBTAT00000026930", "A0A3Q1LVG1", "ENSBTAT00000068978", "F1MN70", "ENSBTAT00000018592", "F1N6L8", "ENSBTAT00000002188", "A0A3Q1MQ82", "ENSBTAT00000083229", "E1BEN9", "ENSBTAT00000020414", "A0A3Q1MGH5", "ENSBTAT00000077814" ] }, "reaction_10041640": { "compartment": "compartment_70101", "id": "reaction_10041640", "reactome": "R-BTA-195300", "name": "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041614" ], "products": [ "species_29370", "species_10041594" ], "modifiers": [ [ "species_10041614", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041629": { "compartment": "compartment_70101", "id": "reaction_10041629", "reactome": "R-BTA-195283", "name": "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041610" ], "products": [ "species_29370", "species_10041614" ], "modifiers": [ [ "species_10041610", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041647": { "compartment": "compartment_70101", "id": "reaction_10041647", "reactome": "R-BTA-195318", "name": "Phosphorylation of beta-catenin at Ser45 by CK1 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041644" ], "products": [ "species_10041634", "species_29370" ], "modifiers": [ [ "species_10041644", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041637": { "compartment": "compartment_70101", "id": "reaction_10041637", "reactome": "R-BTA-195287", "name": "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041634", "species_113592" ], "products": [ "species_29370", "species_10041610" ], "modifiers": [ [ "species_10041634", "catalyst" ], [ "species_10041627", "inhibitor" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "G3N174", "ENSBTAT00000066153", "E1BNA0", "ENSBTAT00000010458", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063849": { "compartment": "compartment_70101", "id": "reaction_10063849", "reactome": "R-BTA-2130286", "name": "Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10063841" ], "products": [ "species_10063845" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10087597": { "compartment": "compartment_7660", "id": "reaction_10087597", "reactome": "R-BTA-8944349", "name": "TLE tetramers bind TCF/LEF at WNT promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067668", "species_10087593" ], "products": [ "species_10087595" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1MZ99", "ENSBTAT00000068676", "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10071356": { "compartment": "compartment_7660", "id": "reaction_10071356", "reactome": "R-BTA-5334050", "name": "TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071346", "species_10071352" ], "products": [ "species_10071354" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN6", "ENSBTAT00000079320", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1M504", "ENSBTAT00000066753", "A0A3Q1MAN6", "ENSBTAT00000079320" ] }, "reaction_10069651": { "compartment": "compartment_7660", "id": "reaction_10069651", "reactome": "R-BTA-4641229", "name": "TLE oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069649" ], "products": [ "species_10067668" ], "modifiers": [], "additional_components": [ "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140", "A0A3Q1LJY1", "ENSBTAT00000079758", "A0A3Q1LTE2", "ENSBTAT00000069289", "A0A3Q1M3K5", "ENSBTAT00000073140" ] }, "reaction_10041583": { "compartment": "compartment_70101", "id": "reaction_10041583", "reactome": "R-BTA-195251", "name": "Assembly of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041574", "species_10041524", "species_10041570", "species_10041520", "species_10041566", "species_10041579" ], "products": [ "species_10041581" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056446", "ENSBTAT00000087508", "ENSBTAT00000011639", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "ENSBTAT00000086393", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10070931": { "compartment": "compartment_70101", "id": "reaction_10070931", "reactome": "R-BTA-5229343", "name": "AXIN is phosphorylated in the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041581" ], "products": [ "species_10041590", "species_29370" ], "modifiers": [ [ "species_10041581", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10063843": { "compartment": "compartment_70101", "id": "reaction_10063843", "reactome": "R-BTA-2130279", "name": "Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10041599" ], "products": [ "species_10063841" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10041604": { "compartment": "compartment_70101", "id": "reaction_10041604", "reactome": "R-BTA-195275", "name": "Phosphorylation of APC component of the destruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041594" ], "products": [ "species_29370", "species_10041599" ], "modifiers": [ [ "species_10041594", "catalyst" ] ], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10041606": { "compartment": "compartment_70101", "id": "reaction_10041606", "reactome": "R-BTA-195280", "name": "Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041599" ], "products": [ "species_10041599" ], "modifiers": [], "additional_components": [ "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446", "A0A3Q1LMC7", "ENSBTAT00000086393", "E1BEW4", "ENSBTAT00000057200", "P35507", "ENSBTAT00000030064", "A0A3Q1MI36", "ENSBTAT00000064284", "A0A3Q1NFM1", "ENSBTAT00000052805", "E1BL05", "ENSBTAT00000011639", "M5FK80", "ENSBTAT00000087508", "F1MIC3", "ENSBTAT00000056446" ] }, "reaction_10060556": { "compartment": "compartment_876", "id": "reaction_10060556", "reactome": "R-BTA-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060448": { "compartment": "compartment_876", "id": "reaction_10060448", "reactome": "R-BTA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806240", "species_113592" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060445", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10087531": { "compartment": "compartment_7660", "id": "reaction_10087531", "reactome": "R-BTA-8943817", "name": "MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087525", "species_10087523" ], "products": [ "species_10087529" ], "modifiers": [], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "A0A3Q1MWB8", "ENSBTAT00000079180" ] }, "reaction_10065099": { "compartment": "compartment_70101", "id": "reaction_10065099", "reactome": "R-BTA-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043178", "species_179856" ], "products": [ "species_10065097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "species_6810412", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10065227": { "compartment": "compartment_70101", "id": "reaction_10065227", "reactome": "R-BTA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10043178" ], "products": [ "species_10036596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039221", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10036981": { "compartment": "compartment_7660", "id": "reaction_10036981", "reactome": "R-BTA-111915", "name": "CAMK4 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10036972" ], "products": [ "species_113582", "species_10036978" ], "modifiers": [ [ "species_10036972", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1M5T5", "ENSBTAT00000086155" ] }, "reaction_10049478": { "compartment": "compartment_70101", "id": "reaction_10049478", "reactome": "R-BTA-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10049470" ], "products": [ "species_113582", "species_10049475" ], "modifiers": [ [ "species_10049470", "catalyst" ] ], "additional_components": [ "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10037022": { "compartment": "compartment_70101", "id": "reaction_10037022", "reactome": "R-BTA-111955", "name": "cAMP hydrolysis by Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037019", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318" ] }, "reaction_10037024": { "compartment": "compartment_70101", "id": "reaction_10037024", "reactome": "R-BTA-111956", "name": "Calmodulin activates Cam-PDE 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037019" ], "products": [ "species_10037019" ], "modifiers": [ [ "species_10037002", "catalyst" ] ], "additional_components": [ "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "A0A3Q1MCV4", "ENSBTAT00000066843", "P14100", "ENSBTAT00000052318", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10037004": { "compartment": "compartment_876", "id": "reaction_10037004", "reactome": "R-BTA-111930", "name": "Adenylate cyclase produces cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10036997", "catalyst" ], [ "species_10037002", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622" ] }, "reaction_10041863": { "compartment": "compartment_876", "id": "reaction_10041863", "reactome": "R-BTA-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10041855" ], "products": [ "species_10041860", "species_29370" ], "modifiers": [ [ "species_10041855", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078659", "ENSBTAT00000078659", "ENSBTAT00000078659" ] }, "reaction_10063544": { "compartment": "compartment_70101", "id": "reaction_10063544", "reactome": "R-BTA-2064406", "name": "Translocation of YAP1:ZO-2 (TJP2) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063538" ], "products": [ "species_10063542" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10063550": { "compartment": "compartment_70101", "id": "reaction_10063550", "reactome": "R-BTA-2064417", "name": "WWTR1 (TAZ) binds ZO-1 (TJP1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063546" ], "products": [ "species_10063548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000038824", "F1N2D3", "ENSBTAT00000038824", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063408": { "compartment": "compartment_70101", "id": "reaction_10063408", "reactome": "R-BTA-2038398", "name": "KIBRA (WWC1) binds LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063404", "species_10063259" ], "products": [ "species_10063406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019472", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "F1N3I6", "ENSBTAT00000019472" ] }, "reaction_10063568": { "compartment": "compartment_70101", "id": "reaction_10063568", "reactome": "R-BTA-2066299", "name": "DVL2 binds phosphorylated WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043149", "species_10063336" ], "products": [ "species_10063566" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078307", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1MSZ4", "ENSBTAT00000078307" ] }, "reaction_10063346": { "compartment": "compartment_70101", "id": "reaction_10063346", "reactome": "R-BTA-2028735", "name": "AMOT proteins bind WWTR1 (TAZ)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10063333" ], "products": [ "species_10063344" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063317": { "compartment": "compartment_70101", "id": "reaction_10063317", "reactome": "R-BTA-2028598", "name": "Phosphorylation of YAP by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063312" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063380": { "compartment": "compartment_70101", "id": "reaction_10063380", "reactome": "R-BTA-2032768", "name": "Translocation of WWTR1 (TAZ) to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333" ], "products": [ "species_10063378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991" ] }, "reaction_10063319": { "compartment": "compartment_70101", "id": "reaction_10063319", "reactome": "R-BTA-2028626", "name": "Phosphorylated MOB1A proteins associate with LATS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063259", "species_10063273" ], "products": [ "species_10063275" ], "modifiers": [], "additional_components": [ "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063382": { "compartment": "compartment_70101", "id": "reaction_10063382", "reactome": "R-BTA-2032770", "name": "Translocation of YAP1 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276" ], "products": [ "species_10057280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112" ] }, "reaction_10063305": { "compartment": "compartment_70101", "id": "reaction_10063305", "reactome": "R-BTA-2028583", "name": "Phosphorylation of YAP by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057276" ], "products": [ "species_29370", "species_10063290" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063338": { "compartment": "compartment_70101", "id": "reaction_10063338", "reactome": "R-BTA-2028661", "name": "Phosphorylation of WWTR1 (TAZ) by LATS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063292", "catalyst" ], [ "species_10063303", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1B9F9", "ENSBTAT00000019161", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063342": { "compartment": "compartment_70101", "id": "reaction_10063342", "reactome": "R-BTA-2028724", "name": "AMOT proteins bind YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063303", "species_10057276" ], "products": [ "species_10063340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M4X1", "ENSBTAT00000077481", "A0A452DIV8", "ENSBTAT00000025212" ] }, "reaction_10063534": { "compartment": "compartment_70101", "id": "reaction_10063534", "reactome": "R-BTA-2060328", "name": "Phosphorylation of WWTR1 (TAZ) by LATS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_113592" ], "products": [ "species_29370", "species_10063336" ], "modifiers": [ [ "species_10063314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000084991", "A0A3Q1M4W1", "ENSBTAT00000081411", "A0A3Q1MBK1", "ENSBTAT00000081480", "E1BCH5", "ENSBTAT00000020062" ] }, "reaction_10063329": { "compartment": "compartment_70101", "id": "reaction_10063329", "reactome": "R-BTA-2028644", "name": "YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10063290" ], "products": [ "species_10063327" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10063554": { "compartment": "compartment_70101", "id": "reaction_10063554", "reactome": "R-BTA-2064418", "name": "WWTR1 (TAZ) binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063333", "species_10063536" ], "products": [ "species_10063552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084991", "ENSBTAT00000069935", "A0A3Q1MEH9", "ENSBTAT00000069935", "A0A3Q1NBB6", "ENSBTAT00000084991" ] }, "reaction_10063556": { "compartment": "compartment_70101", "id": "reaction_10063556", "reactome": "R-BTA-2064421", "name": "YAP1 binds ZO-2 (TJP2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063536", "species_10057276" ], "products": [ "species_10063538" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069935", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MEH9", "ENSBTAT00000069935" ] }, "reaction_10043753": { "compartment": "compartment_70101", "id": "reaction_10043753", "reactome": "R-BTA-205075", "name": "JNK phosphorylates BIM, BAD and other targets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037714", "species_113592", "species_10037676" ], "products": [ "species_10043750", "species_29370", "species_10043747" ], "modifiers": [ [ "species_10039514", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000078264", "ENSBTAT00000016610", "ENSBTAT00000087439" ] }, "reaction_10041333": { "compartment": "compartment_13231", "id": "reaction_10041333", "reactome": "R-BTA-193666", "name": "Active JNK moves to the nucleus and phosphorylates different transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039514" ], "products": [ "species_10039497" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087439", "ENSBTAT00000087439" ] }, "reaction_10043739": { "compartment": "compartment_13231", "id": "reaction_10043739", "reactome": "R-BTA-204947", "name": "Polyubiquitinated NRIF migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043729" ], "products": [ "species_10043737" ], "modifiers": [], "additional_components": [ "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119" ] }, "reaction_10043744": { "compartment": "compartment_70101", "id": "reaction_10043744", "reactome": "R-BTA-205008", "name": "Polyubiquitinated NRIF binds to p62 (Sequestosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043741", "species_10043723" ], "products": [ "species_10043729" ], "modifiers": [ [ "species_10043723", "catalyst" ] ], "additional_components": [ "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019", "A0A3Q1LVE4", "ENSBTAT00000075019", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000075019" ] }, "reaction_10043778": { "compartment": "compartment_70101", "id": "reaction_10043778", "reactome": "R-BTA-205118", "name": "TRAF6 polyubiquitinates NRIF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043719", "species_10043727" ], "products": [ "species_10043741" ], "modifiers": [ [ "species_10043761", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000083119", "A0A3Q1M6A8", "ENSBTAT00000083119", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10043877": { "compartment": "compartment_70101", "id": "reaction_10043877", "reactome": "R-BTA-209536", "name": "IkB is ubiquitinated and degraded", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043858", "species_10033408" ], "products": [ "species_10043875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022183", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10041470": { "compartment": "compartment_876", "id": "reaction_10041470", "reactome": "R-BTA-194518", "name": "RhoA is activated by nucleotide exchange and inhibits axonal growth", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037313" ], "products": [ "species_10037315" ], "modifiers": [ [ "species_10041467", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000083879" ] }, "reaction_10071524": { "compartment": "compartment_876", "id": "reaction_10071524", "reactome": "R-BTA-5357757", "name": "BIRC(cIAP1/2) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10071516" ], "products": [ "species_10071521" ], "modifiers": [ [ "species_10071516", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10071556": { "compartment": "compartment_70101", "id": "reaction_10071556", "reactome": "R-BTA-5357904", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071552", "species_10071521" ], "products": [ "species_10071554" ], "modifiers": [], "additional_components": [ "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "E1BMK3", "ENSBTAT00000061147", "Q1JPC8", "ENSBTAT00000022612", "E1BDF2", "ENSBTAT00000049670" ] }, "reaction_10071526": { "compartment": "compartment_876", "id": "reaction_10071526", "reactome": "R-BTA-5357780", "name": "TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036142", "species_10071514" ], "products": [ "species_10071516" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869" ] }, "reaction_10037964": { "compartment": "compartment_70101", "id": "reaction_10037964", "reactome": "R-BTA-140978", "name": "TRADD:TRAF2:RIP1 complex binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035378", "species_10036144" ], "products": [ "species_10037952" ], "modifiers": [ [ "species_10037962", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10067908": { "compartment": "compartment_984", "id": "reaction_10067908", "reactome": "R-BTA-3371385", "name": "TNF-alpha is cleaved by ADAM17 (TACE)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036154" ], "products": [ "species_10067885", "species_10067899" ], "modifiers": [ [ "species_10067905", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "A0A452DJ61", "ENSBTAT00000035815", "species_29426", "E1B867", "ENSBTAT00000001519" ] }, "reaction_10092026": { "compartment": "compartment_70101", "id": "reaction_10092026", "reactome": "R-BTA-9697747", "name": "Caspase-8 and FLIP(L) processing at TNFR signaling complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067893" ], "products": [ "species_10092024", "species_10068040" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10092031": { "compartment": "compartment_70101", "id": "reaction_10092031", "reactome": "R-BTA-9697750", "name": "RIPK1 is cleaved by CASP8:FLIP(L)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092024" ], "products": [ "species_10092028", "species_10071528" ], "modifiers": [ [ "species_10092024", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10071534": { "compartment": "compartment_70101", "id": "reaction_10071534", "reactome": "R-BTA-5357828", "name": "RIPK1 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952" ], "products": [ "species_10071532", "species_10071528" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "Q645M6", "ENSBTAT00000024322", "E1B9D9", "ENSBTAT00000013869", "ENSBTAT00000008367", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10084723": { "compartment": "compartment_70101", "id": "reaction_10084723", "reactome": "R-BTA-8863101", "name": "SPPL2a/b cleaves TNF(1-76)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067899" ], "products": [ "species_10084710", "species_10084708" ], "modifiers": [ [ "species_10084720", "catalyst" ] ], "additional_components": [ "A0A452DJ61", "ENSBTAT00000035815", "ENSBTAT00000035815", "ENSBTAT00000035815", "A0A3Q1MBP7", "ENSBTAT00000077127", "E1BKF8", "ENSBTAT00000035792" ] }, "reaction_10071541": { "compartment": "compartment_70101", "id": "reaction_10071541", "reactome": "R-BTA-5357845", "name": "RIPK1 is deubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071521" ], "products": [ "species_10033408", "species_10071516" ], "modifiers": [ [ "species_10037962", "catalyst" ], [ "species_10071539", "catalyst" ] ], "additional_components": [ "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "A0A3Q1NKI9", "ENSBTAT00000069028", "ENSBTAT00000026221" ] }, "reaction_10067895": { "compartment": "compartment_70101", "id": "reaction_10067895", "reactome": "R-BTA-3371360", "name": "FLIP(L) and procaspase-8 form heterodimer in TNF signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037952", "species_10067887", "species_10035384" ], "products": [ "species_10067893" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322" ] }, "reaction_10035726": { "compartment": "compartment_876", "id": "reaction_10035726", "reactome": "R-BTA-75244", "name": "FASL binds FAS Receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033920", "species_10033916" ], "products": [ "species_10033922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014282", "ENSBTAT00000046575", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036146": { "compartment": "compartment_876", "id": "reaction_10036146", "reactome": "R-BTA-83586", "name": "FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035380", "species_10035384" ], "products": [ "species_10035386" ], "modifiers": [], "additional_components": [ "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10036148": { "compartment": "compartment_876", "id": "reaction_10036148", "reactome": "R-BTA-83650", "name": "FasL:Fas binds FADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033924", "species_10035378" ], "products": [ "species_10035380" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000024322", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10033926": { "compartment": "compartment_876", "id": "reaction_10033926", "reactome": "R-BTA-71050", "name": "Trimerization of the FASL:FAS receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033922" ], "products": [ "species_10033924" ], "modifiers": [], "additional_components": [ "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10045016": { "compartment": "compartment_70101", "id": "reaction_10045016", "reactome": "R-BTA-354173", "name": "Activation of Rap1 by cytosolic GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10045013", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "species_74016", "species_6797635", "E1BG59", "ENSBTAT00000029159" ] }, "reaction_10053213": { "compartment": "compartment_70101", "id": "reaction_10053213", "reactome": "R-BTA-939265", "name": "Activation of Rap1 by membrane-associated GEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10045007" ], "products": [ "species_29420", "species_10045005" ], "modifiers": [ [ "species_10047532", "catalyst" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10049279": { "compartment": "compartment_876", "id": "reaction_10049279", "reactome": "R-BTA-432110", "name": "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037443" ], "products": [ "species_10049276" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "F1MTN1", "ENSBTAT00000013173", "F1MGZ4", "ENSBTAT00000010738", "ENSBTAT00000039221" ] }, "reaction_10049506": { "compartment": "compartment_876", "id": "reaction_10049506", "reactome": "R-BTA-443905", "name": "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049502" ], "products": [ "species_10049504" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "E1BIM8", "ENSBTAT00000011767", "F1MGZ4", "ENSBTAT00000010738", "F1MTN1", "ENSBTAT00000013173", "species_6810412", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "A0A3Q1MLQ7", "ENSBTAT00000074863", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10071673": { "compartment": "compartment_70101", "id": "reaction_10071673", "reactome": "R-BTA-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071670", "catalyst" ] ], "additional_components": [ "F1MFZ4", "ENSBTAT00000003769", "species_29426", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10076840": { "compartment": "compartment_70101", "id": "reaction_10076840", "reactome": "R-BTA-5696101", "name": "ALDH8A1 oxidises 9cRAL to 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5362565", "species_29360" ], "products": [ "species_70106", "species_5362520", "species_73473" ], "modifiers": [ [ "species_10076837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010485" ] }, "reaction_10071691": { "compartment": "compartment_70101", "id": "reaction_10071691", "reactome": "R-BTA-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10071688", "catalyst" ] ], "additional_components": [ "F1MZD5", "ENSBTAT00000023493", "E1BM93", "ENSBTAT00000002535", "Q17QW3", "ENSBTAT00000006933" ] }, "reaction_10071659": { "compartment": "compartment_70101", "id": "reaction_10071659", "reactome": "R-BTA-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975622", "species_29360" ], "products": [ "species_70106", "species_5334816", "species_73473" ], "modifiers": [ [ "species_10071656", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661", "F1MHR3", "ENSBTAT00000012030" ] }, "reaction_10072397": { "compartment": "compartment_70101", "id": "reaction_10072397", "reactome": "R-BTA-5622134", "name": "CRABP1 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071664", "species_5334816" ], "products": [ "species_10071666" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017158", "species_215573", "P62964", "ENSBTAT00000017158" ] }, "reaction_10071678": { "compartment": "compartment_70101", "id": "reaction_10071678", "reactome": "R-BTA-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_29360" ], "products": [ "species_70106", "species_32737", "species_73473" ], "modifiers": [ [ "species_10071675", "catalyst" ] ], "additional_components": [ "Q27979", "ENSBTAT00000065932", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10072433": { "compartment": "compartment_70616", "id": "reaction_10072433", "reactome": "R-BTA-5623643", "name": "RDH13 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623644", "species_5623648", "species_163953" ], "products": [ "species_5623650", "species_5623649" ], "modifiers": [ [ "species_10072430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029403" ] }, "reaction_10072225": { "compartment": "compartment_70101", "id": "reaction_10072225", "reactome": "R-BTA-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_975622", "species_29364" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10041165", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086" ] }, "reaction_10071648": { "compartment": "compartment_70101", "id": "reaction_10071648", "reactome": "R-BTA-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_975622", "species_73473" ], "modifiers": [ [ "species_10071645", "catalyst" ] ], "additional_components": [ "Q8HYR6", "ENSBTAT00000005986", "Q0V8D0", "ENSBTAT00000001829", "Q8HZT6", "ENSBTAT00000026830" ] }, "reaction_10044211": { "compartment": "compartment_12045", "id": "reaction_10044211", "reactome": "R-BTA-211923", "name": "CYP26C1 4-hydroxylates 9cRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5362520", "species_29368", "species_29364" ], "products": [ "species_5362524", "species_29356", "species_29366" ], "modifiers": [ [ "species_10044208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056396" ] }, "reaction_10071668": { "compartment": "compartment_70101", "id": "reaction_10071668", "reactome": "R-BTA-5362525", "name": "CYP26A1,B1,C1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10071666", "species_29368", "species_29364" ], "products": [ "species_29356", "species_10071664", "species_5362521", "species_29366" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "species_215573", "P62964", "ENSBTAT00000017158", "ENSBTAT00000017158", "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10071407": { "compartment": "compartment_7660", "id": "reaction_10071407", "reactome": "R-BTA-5334854", "name": "RAR:RXR binds SUMO-CRABP2:atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071399", "species_10071403" ], "products": [ "species_10071405" ], "modifiers": [], "additional_components": [ "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860" ] }, "reaction_10071397": { "compartment": "compartment_70101", "id": "reaction_10071397", "reactome": "R-BTA-5334827", "name": "SUMO-CRABP2 binds atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071393", "species_5334816" ], "products": [ "species_10071395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087158", "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158" ] }, "reaction_10072628": { "compartment": "compartment_7660", "id": "reaction_10072628", "reactome": "R-BTA-5634103", "name": "SUMO-CRABP2 dissociates from atRA:RAR:RXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071405" ], "products": [ "species_10072626", "species_10071401" ], "modifiers": [], "additional_components": [ "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "species_215573", "G3X6X1", "ENSBTAT00000015305", "A6H7I6", "ENSBTAT00000000860", "ENSBTAT00000087158" ] }, "reaction_10072630": { "compartment": "compartment_70101", "id": "reaction_10072630", "reactome": "R-BTA-5634104", "name": "SUMO-CRABP2:atRA translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071395" ], "products": [ "species_10071403" ], "modifiers": [], "additional_components": [ "species_215573", "A0A3Q1LX32", "ENSBTAT00000087158", "A0A3Q1LX32", "ENSBTAT00000087158", "species_215573" ] }, "reaction_10090456": { "compartment": "compartment_7660", "id": "reaction_10090456", "reactome": "R-BTA-9024334", "name": "Co-repressor complex dissociates from the transcription unit of the ABCA1 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090450" ], "products": [ "species_10090454", "species_10090444" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090559": { "compartment": "compartment_7660", "id": "reaction_10090559", "reactome": "R-BTA-9029551", "name": "NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090454", "species_10047785" ], "products": [ "species_10090557" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090563": { "compartment": "compartment_7660", "id": "reaction_10090563", "reactome": "R-BTA-9029561", "name": "NCOA1 recruits EP300 to the ABCA1 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10090557" ], "products": [ "species_10090561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10090452": { "compartment": "compartment_7660", "id": "reaction_10090452", "reactome": "R-BTA-9024326", "name": "Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090448", "species_9024383" ], "products": [ "species_10090450" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MPA7", "ENSBTAT00000013888", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090555": { "compartment": "compartment_7660", "id": "reaction_10090555", "reactome": "R-BTA-9029517", "name": "Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090551", "species_9024383" ], "products": [ "species_10090553" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10090571": { "compartment": "compartment_7660", "id": "reaction_10090571", "reactome": "R-BTA-9029580", "name": "NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090565", "species_10047785" ], "products": [ "species_10090569" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "ENSBTAT00000064008", "G3N0C2", "ENSBTAT00000064008", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090567": { "compartment": "compartment_7660", "id": "reaction_10090567", "reactome": "R-BTA-9029566", "name": "Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090553" ], "products": [ "species_10044694", "species_10090565" ], "modifiers": [], "additional_components": [ "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "Q5E9B6", "ENSBTAT00000071739", "A6H7I6", "ENSBTAT00000000860", "species_192060", "CHEBI:67237", "species_9024328", "CHEBI:41633" ] }, "reaction_10090712": { "compartment": "compartment_7660", "id": "reaction_10090712", "reactome": "R-BTA-9038029", "name": "27-hydroxysterol binds ESR1, ESR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045570", "species_9024328" ], "products": [ "species_10090710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005899", "species_9024328", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10092314": { "compartment": "compartment_7660", "id": "reaction_10092314", "reactome": "R-BTA-9709547", "name": "ESTG binds ESR2:chaperone complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086682", "species_1254400" ], "products": [ "species_10086684" ], "modifiers": [], "additional_components": [ "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180", "species_1254400", "A0A452DIU3", "ENSBTAT00000023908", "species_113592", "Q9XSB5", "ENSBTAT00000005899", "P26882", "ENSBTAT00000022180" ] }, "reaction_10089761": { "compartment": "compartment_7660", "id": "reaction_10089761", "reactome": "R-BTA-9011981", "name": "EP300 is recruited to MYC and BCL2 genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053052", "species_10089757" ], "products": [ "species_10089759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021556", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_1254400", "Q2HJ27", "ENSBTAT00000076263", "F2Z4J1", "ENSBTAT00000056983", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556" ] }, "reaction_10091115": { "compartment": "compartment_876", "id": "reaction_10091115", "reactome": "R-BTA-9624272", "name": "MMPs cleave HB-EGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091106" ], "products": [ "species_10091108", "species_10040221" ], "modifiers": [ [ "species_10091110", "catalyst" ], [ "species_10091113", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000029015", "ENSBTAT00000029015", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10091275": { "compartment": "compartment_876", "id": "reaction_10091275", "reactome": "R-BTA-9632918", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091269" ], "products": [ "species_10091273" ], "modifiers": [], "additional_components": [ "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091260": { "compartment": "compartment_876", "id": "reaction_10091260", "reactome": "R-BTA-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091252", "species_113592" ], "products": [ "species_29370", "species_10091257" ], "modifiers": [ [ "species_10091252", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838" ] }, "reaction_10091271": { "compartment": "compartment_876", "id": "reaction_10091271", "reactome": "R-BTA-9632906", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040312", "species_10091257" ], "products": [ "species_10091269" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "F1MQJ7", "ENSBTAT00000039221", "species_179838", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10091151": { "compartment": "compartment_876", "id": "reaction_10091151", "reactome": "R-BTA-9625482", "name": "PTK2 binds activated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043033" ], "products": [ "species_10091149" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000085237", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091156": { "compartment": "compartment_876", "id": "reaction_10091156", "reactome": "R-BTA-9625487", "name": "PTK2 autophosphorylates downstream of EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10091149" ], "products": [ "species_29370", "species_10091153" ], "modifiers": [ [ "species_10091149", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1N508", "ENSBTAT00000085237", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10091118": { "compartment": "compartment_7660", "id": "reaction_10091118", "reactome": "R-BTA-9624527", "name": "AKT-phosphorylated FOXO3 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042685" ], "products": [ "species_10091011" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10091267": { "compartment": "compartment_7660", "id": "reaction_10091267", "reactome": "R-BTA-9632873", "name": "p-S10 CDKN1B translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091263" ], "products": [ "species_10091265" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "ENSBTAT00000017629" ] }, "reaction_10091158": { "compartment": "compartment_876", "id": "reaction_10091158", "reactome": "R-BTA-9625813", "name": "S1P binds S1PR3 in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5218688", "species_10046309" ], "products": [ "species_10091113" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015111", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10086662": { "compartment": "compartment_7660", "id": "reaction_10086662", "reactome": "R-BTA-8939201", "name": "ESR dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086658" ], "products": [ "species_10086660" ], "modifiers": [], "additional_components": [ "species_1254400", "Q9XSB5", "ENSBTAT00000005899", "species_1254400", "Q9XSB5", "ENSBTAT00000005899" ] }, "reaction_10086575": { "compartment": "compartment_984", "id": "reaction_10086575", "reactome": "R-BTA-8937631", "name": "CRHR2-2 binds CRH,UCN,UCN2,UCN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10086571" ], "products": [ "species_10086573" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "F1MKP4", "ENSBTAT00000025398", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10048270": { "compartment": "compartment_984", "id": "reaction_10048270", "reactome": "R-BTA-420173", "name": "CRHR1,CRHR2-1 binds CRH,UCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048262", "species_10048266" ], "products": [ "species_10048268" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081022", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A0A3Q1N5S8", "ENSBTAT00000081022" ] }, "reaction_10049681": { "compartment": "compartment_984", "id": "reaction_10049681", "reactome": "R-BTA-444773", "name": "EGF-TM7 receptors bind chondroitin sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444761", "species_10049677" ], "products": [ "species_10049679" ], "modifiers": [], "additional_components": [ "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1M8L4", "ENSBTAT00000082095", "A0A3Q1M0R0", "ENSBTAT00000081916", "species_444761" ] }, "reaction_10051907": { "compartment": "compartment_876", "id": "reaction_10051907", "reactome": "R-BTA-879674", "name": "CD97 binds CD55", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049671", "species_10051903" ], "products": [ "species_10051905" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081916", "ENSBTAT00000078403", "A0A3Q1LQX2", "ENSBTAT00000078403", "A0A3Q1M0R0", "ENSBTAT00000081916" ] }, "reaction_10086565": { "compartment": "compartment_984", "id": "reaction_10086565", "reactome": "R-BTA-8937613", "name": "CRHBP binds CRH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086561", "species_10048266" ], "products": [ "species_10086563" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026905", "ENSBTAT00000047063", "Q95MI6", "ENSBTAT00000047063", "A7MBA3", "ENSBTAT00000026905" ] }, "reaction_10048248": { "compartment": "compartment_984", "id": "reaction_10048248", "reactome": "R-BTA-420123", "name": "Glucagon-like receptor 2 binds GLP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048244", "species_10048242" ], "products": [ "species_10048246" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000006662", "E1BAY1", "ENSBTAT00000006662", "P01272", "ENSBTAT00000000972" ] }, "reaction_10048282": { "compartment": "compartment_984", "id": "reaction_10048282", "reactome": "R-BTA-420202", "name": "Secretin receptor binds secretin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048278", "species_10048274" ], "products": [ "species_10048280" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071185", "ENSBTAT00000079270", "A0A3Q1MB83", "ENSBTAT00000079270", "A0A3Q1M5G0", "ENSBTAT00000071185" ] }, "reaction_10048304": { "compartment": "compartment_984", "id": "reaction_10048304", "reactome": "R-BTA-420233", "name": "VIP receptors bind VIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048290", "species_10048300" ], "products": [ "species_10048302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017827", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "F1MIT6", "ENSBTAT00000047461", "F1MF07", "ENSBTAT00000008625", "P81401", "ENSBTAT00000017827" ] }, "reaction_10038918": { "compartment": "compartment_984", "id": "reaction_10038918", "reactome": "R-BTA-163625", "name": "Glucagon binds to Glucagon receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038912", "species_10038908" ], "products": [ "species_10038916" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "ENSBTAT00000000972", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10048326": { "compartment": "compartment_984", "id": "reaction_10048326", "reactome": "R-BTA-420489", "name": "Parathyroid hormone receptor can bind parathyroid hormone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048322", "species_10048312" ], "products": [ "species_10048324" ], "modifiers": [], "additional_components": [ "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408", "ENSBTAT00000061196", "E1B7Q8", "ENSBTAT00000061196", "P58073", "ENSBTAT00000043154", "E1B9U9", "ENSBTAT00000001408" ] }, "reaction_10091763": { "compartment": "compartment_984", "id": "reaction_10091763", "reactome": "R-BTA-9684627", "name": "CYSLTR1 binds CYSLTR1 antagonists", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_9684615" ], "products": [ "species_10091761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047378": { "compartment": "compartment_984", "id": "reaction_10047378", "reactome": "R-BTA-391937", "name": "UDP/CysLT receptor can bind cysteinyl leukotrienes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_416372" ], "products": [ "species_10046259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047396": { "compartment": "compartment_984", "id": "reaction_10047396", "reactome": "R-BTA-391941", "name": "BLT receptors can bind LTB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045934", "species_416436" ], "products": [ "species_10045936" ], "modifiers": [], "additional_components": [ "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992" ] }, "reaction_10091812": { "compartment": "compartment_984", "id": "reaction_10091812", "reactome": "R-BTA-9690439", "name": "CYSLTR1 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045862", "species_416372" ], "products": [ "species_10045864" ], "modifiers": [ [ "species_10091761", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034352", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10047398": { "compartment": "compartment_984", "id": "reaction_10047398", "reactome": "R-BTA-391943", "name": "CYSLT2 binds LTC4,LTD4,LTE4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038914", "species_416372" ], "products": [ "species_10045866" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023275", "species_266074", "species_266013", "CHEBI:15650", "species_266074", "species_266013", "CHEBI:15650", "A7MBH4", "ENSBTAT00000023275" ] }, "reaction_10047374": { "compartment": "compartment_984", "id": "reaction_10047374", "reactome": "R-BTA-391935", "name": "DP1 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416911", "species_10047370" ], "products": [ "species_10047372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008808", "A0A452DI56", "ENSBTAT00000008808", "species_416911" ] }, "reaction_10047376": { "compartment": "compartment_984", "id": "reaction_10047376", "reactome": "R-BTA-391936", "name": "EP1 receptor can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10045990" ], "products": [ "species_10045992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046806", "species_391930", "F1MUY4", "ENSBTAT00000046806" ] }, "reaction_10047394": { "compartment": "compartment_984", "id": "reaction_10047394", "reactome": "R-BTA-391940", "name": "EP2 and EP4 receptors can bind PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391930", "species_10047390" ], "products": [ "species_10047392" ], "modifiers": [], "additional_components": [ "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "F1N2L8", "ENSBTAT00000002800", "F1MZJ8", "ENSBTAT00000019930", "species_391930" ] }, "reaction_10047380": { "compartment": "compartment_984", "id": "reaction_10047380", "reactome": "R-BTA-391939", "name": "TP receptor can bind thromboxane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_391932", "species_10045856" ], "products": [ "species_10045858" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10047366": { "compartment": "compartment_984", "id": "reaction_10047366", "reactome": "R-BTA-391934", "name": "DP2 receptor can bind PGD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046263", "species_416911" ], "products": [ "species_10046265" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066986", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986" ] }, "reaction_10047364": { "compartment": "compartment_984", "id": "reaction_10047364", "reactome": "R-BTA-391905", "name": "Oxoeicosanoid receptor can bind oxoeicosanoid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_416428", "species_10046299" ], "products": [ "species_10046301" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005326", "F1MCJ0", "ENSBTAT00000005326", "species_416428" ] }, "reaction_10049657": { "compartment": "compartment_984", "id": "reaction_10049657", "reactome": "R-BTA-444654", "name": "G-protein coupled bile acid receptor binds lithocholic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444840", "species_10049653" ], "products": [ "species_10049655" ], "modifiers": [], "additional_components": [ "species_5357505", "species_193451", "species_176655", "CHEBI:16755", "ENSBTAT00000005120", "Q862A9", "ENSBTAT00000005120", "species_5357505", "species_193451", "species_176655", "CHEBI:16755" ] }, "reaction_10047354": { "compartment": "compartment_984", "id": "reaction_10047354", "reactome": "R-BTA-391375", "name": "Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047350", "species_10047338" ], "products": [ "species_10047352" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524", "ENSBTAT00000052615", "F1N4F6", "ENSBTAT00000052615", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264", "E1BD70", "ENSBTAT00000009286", "A0A0F7RPV8", "ENSBTAT00000075524" ] }, "reaction_10047362": { "compartment": "compartment_984", "id": "reaction_10047362", "reactome": "R-BTA-391377", "name": "Luteinizing hormone receptor can bind LH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041267", "species_10047358" ], "products": [ "species_10047360" ], "modifiers": [], "additional_components": [ "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054", "ENSBTAT00000022047", "A0A140T893", "ENSBTAT00000022047", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10047334": { "compartment": "compartment_984", "id": "reaction_10047334", "reactome": "R-BTA-391372", "name": "Gonadotropin-releasing hormone receptors can bind GNRH I and II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045798", "species_10045788" ], "products": [ "species_10045800" ], "modifiers": [], "additional_components": [ "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "ENSBTAT00000000559", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568" ] }, "reaction_10049659": { "compartment": "compartment_984", "id": "reaction_10049659", "reactome": "R-BTA-444661", "name": "HCAR2 binds HCAR2 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296262", "species_10046459" ], "products": [ "species_10046461" ], "modifiers": [], "additional_components": [ "CHEBI:20067", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230" ] }, "reaction_10048208": { "compartment": "compartment_984", "id": "reaction_10048208", "reactome": "R-BTA-419841", "name": "Light stimulates opsin receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10048204" ], "products": [ "species_10048206" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10048214": { "compartment": "compartment_984", "id": "reaction_10048214", "reactome": "R-BTA-419861", "name": "Melanospin is stimulated by light", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10045850" ], "products": [ "species_10045852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000040059", "E1BEK2", "ENSBTAT00000040059", "species_419777" ] }, "reaction_10045180": { "compartment": "compartment_984", "id": "reaction_10045180", "reactome": "R-BTA-373339", "name": "Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045172", "species_10045176" ], "products": [ "species_10045178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013116", "ENSBTAT00000026663", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116" ] }, "reaction_10067358": { "compartment": "compartment_876", "id": "reaction_10067358", "reactome": "R-BTA-3296301", "name": "CCRL2 binds CCL19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049514", "species_10067354" ], "products": [ "species_10067356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016850", "ENSBTAT00000008096", "Q0II78", "ENSBTAT00000008096", "Q3ZBN3", "ENSBTAT00000016850" ] }, "reaction_10045168": { "compartment": "compartment_984", "id": "reaction_10045168", "reactome": "R-BTA-373087", "name": "Receptor CCR6 binds CCL20 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045164", "species_10045160" ], "products": [ "species_10045166" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028430", "ENSBTAT00000037034", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430" ] }, "reaction_10045072": { "compartment": "compartment_984", "id": "reaction_10045072", "reactome": "R-BTA-373061", "name": "Receptors CCR3, 4 and 5 bind CCL5 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045054", "species_10045068" ], "products": [ "species_10045070" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082438", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438" ] }, "reaction_10049520": { "compartment": "compartment_984", "id": "reaction_10049520", "reactome": "R-BTA-443978", "name": "Receptor CCR11 binds CCL19, CCL21 & CCL25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049510", "species_10049516" ], "products": [ "species_10049518" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026082", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "Q3ZBN3", "ENSBTAT00000016850", "Q1RMQ0", "ENSBTAT00000007331", "P35350", "ENSBTAT00000026082" ] }, "reaction_10045106": { "compartment": "compartment_984", "id": "reaction_10045106", "reactome": "R-BTA-373074", "name": "Receptor CCR9 binds CCL25 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045102", "species_10045098" ], "products": [ "species_10045104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078248", "ENSBTAT00000007331", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248" ] }, "reaction_10045268": { "compartment": "compartment_984", "id": "reaction_10045268", "reactome": "R-BTA-374214", "name": "Receptors CXCR4 and 7 bind CXCL12 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045264", "species_10045260" ], "products": [ "species_10045266" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980" ] }, "reaction_10083880": { "compartment": "compartment_876", "id": "reaction_10083880", "reactome": "R-BTA-8851352", "name": "CCR8 binds CCL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046469", "species_10045080" ], "products": [ "species_10046471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047653", "ENSBTAT00000020577", "F6RDR3", "ENSBTAT00000020577", "E1BAG6", "ENSBTAT00000047653" ] }, "reaction_10045196": { "compartment": "compartment_984", "id": "reaction_10045196", "reactome": "R-BTA-373358", "name": "Receptor CXCR6 binds CXCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045188", "species_10045192" ], "products": [ "species_10045194" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020855", "ENSBTAT00000024371", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855" ] }, "reaction_10045280": { "compartment": "compartment_984", "id": "reaction_10045280", "reactome": "R-BTA-374248", "name": "Receptor CXCR3 binds ligands CXCL9 to 11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045276", "species_10045272" ], "products": [ "species_10045278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019690", "ENSBTAT00000075648", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690" ] }, "reaction_10049570": { "compartment": "compartment_984", "id": "reaction_10049570", "reactome": "R-BTA-443986", "name": "Receptor ACKR2 binds most inflammatory CC chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049524", "species_10049566" ], "products": [ "species_10049568" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068509", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "P28291", "ENSBTAT00000013146", "A5PKF1", "ENSBTAT00000023564", "Q17QA1", "ENSBTAT00000009446", "E1BGB8", "ENSBTAT00000004257", "P82943", "ENSBTAT00000013399", "A0A3Q1LTV3", "ENSBTAT00000071668", "A0A3Q1NB11", "ENSBTAT00000085385", "F1MYS4", "ENSBTAT00000035430", "O97919", "ENSBTAT00000082438", "Q9TTS6", "ENSBTAT00000005406", "F1MIF0", "ENSBTAT00000001579", "A0A3Q1LTZ4", "ENSBTAT00000068509" ] }, "reaction_10045156": { "compartment": "compartment_984", "id": "reaction_10045156", "reactome": "R-BTA-373086", "name": "Receptor CCR10 binds CCL27 and 28 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045142", "species_10045152" ], "products": [ "species_10045154" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025420", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420" ] }, "reaction_10049639": { "compartment": "compartment_984", "id": "reaction_10049639", "reactome": "R-BTA-444523", "name": "CXCR5 binds CXCL13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046161", "species_10046157" ], "products": [ "species_10046163" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011164", "ENSBTAT00000063808", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164" ] }, "reaction_10045094": { "compartment": "compartment_984", "id": "reaction_10045094", "reactome": "R-BTA-373073", "name": "Receptors CCR1, 2 and 8 bind CCL16 ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045090", "species_10045086" ], "products": [ "species_10045092" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079349", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349" ] }, "reaction_10091037": { "compartment": "compartment_984", "id": "reaction_10091037", "reactome": "R-BTA-9615249", "name": "ARBs bind AGRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9615246", "species_10045250" ], "products": [ "species_10091035" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063575", "P25104", "ENSBTAT00000063575" ] }, "reaction_10046731": { "compartment": "compartment_984", "id": "reaction_10046731", "reactome": "R-BTA-388468", "name": "AVP(20-28) binds AVPR1A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10045810" ], "products": [ "species_10045816" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10047483": { "compartment": "compartment_984", "id": "reaction_10047483", "reactome": "R-BTA-392263", "name": "AVP(20-28) binds AVPR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045814", "species_10047479" ], "products": [ "species_10047481" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076190", "ENSBTAT00000065044", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190" ] }, "reaction_10046733": { "compartment": "compartment_984", "id": "reaction_10046733", "reactome": "R-BTA-388503", "name": "Oxytocin receptor bind oxytocin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045970", "species_10045966" ], "products": [ "species_10045972" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026346", "ENSBTAT00000010554", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346" ] }, "reaction_10049661": { "compartment": "compartment_984", "id": "reaction_10049661", "reactome": "R-BTA-444691", "name": "Prokineticin receptors bind prokineticin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046036", "species_10046032" ], "products": [ "species_10046038" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013959", "ENSBTAT00000021097", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959" ] }, "reaction_10046729": { "compartment": "compartment_984", "id": "reaction_10046729", "reactome": "R-BTA-383373", "name": "Tachykinin receptor 3 (NK3) binds to neurokinin B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045940", "species_10045944" ], "products": [ "species_10045946" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029067", "ENSBTAT00000021612", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067" ] }, "reaction_10045406": { "compartment": "compartment_984", "id": "reaction_10045406", "reactome": "R-BTA-374787", "name": "GPCR neuropeptide receptor binds neuropeptides B and W", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045398", "species_10045402" ], "products": [ "species_10045404" ], "modifiers": [], "additional_components": [ "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "ENSBTAT00000021510", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382" ] }, "reaction_10045362": { "compartment": "compartment_984", "id": "reaction_10045362", "reactome": "R-BTA-374723", "name": "Nociceptin receptor binds to nociceptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045358", "species_10045354" ], "products": [ "species_10045360" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084136", "ENSBTAT00000000695", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136" ] }, "reaction_10046773": { "compartment": "compartment_984", "id": "reaction_10046773", "reactome": "R-BTA-388605", "name": "POMC(138-176) binds MC2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046769", "species_10046767" ], "products": [ "species_10046771" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010386", "ENSBTAT00000014661", "P34974", "ENSBTAT00000014661", "P01190", "ENSBTAT00000010386" ] }, "reaction_10045332": { "compartment": "compartment_984", "id": "reaction_10045332", "reactome": "R-BTA-374331", "name": "Bradykinin receptors B1 and B2 bind to bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038198", "species_10045328" ], "products": [ "species_10045330" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053071", "ENSBTAT00000078035", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071" ] }, "reaction_10053335": { "compartment": "compartment_876", "id": "reaction_10053335", "reactome": "R-BTA-964800", "name": "Neuromedin-U receptors bind neuromedins U, S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046114", "species_10046110" ], "products": [ "species_10046116" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061371", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371" ] }, "reaction_10054775": { "compartment": "compartment_876", "id": "reaction_10054775", "reactome": "R-BTA-981832", "name": "NMUR2 binds neuromedin-S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046102", "species_10046098" ], "products": [ "species_10046104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048447", "ENSBTAT00000014782", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447" ] }, "reaction_10046953": { "compartment": "compartment_984", "id": "reaction_10046953", "reactome": "R-BTA-389463", "name": "Proteinase-activated receptors can bind thrombin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045984", "species_10037577" ], "products": [ "species_10045986" ], "modifiers": [], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191" ] }, "reaction_10045384": { "compartment": "compartment_984", "id": "reaction_10045384", "reactome": "R-BTA-374758", "name": "Somatostatin receptors bind somatostatin and cortistatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045366", "species_10045380" ], "products": [ "species_10045382" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063299", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299" ] }, "reaction_10046763": { "compartment": "compartment_984", "id": "reaction_10046763", "reactome": "R-BTA-388596", "name": "Melanocortin receptors bind melanocortins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046759", "species_10046737" ], "products": [ "species_10046761" ], "modifiers": [], "additional_components": [ "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049", "ENSBTAT00000010386", "P01190", "ENSBTAT00000010386", "P47798", "ENSBTAT00000032494", "E1B8V8", "ENSBTAT00000006185", "Q9GLJ8", "ENSBTAT00000026223", "P56451", "ENSBTAT00000012049" ] }, "reaction_10049645": { "compartment": "compartment_984", "id": "reaction_10049645", "reactome": "R-BTA-444620", "name": "Neuropeptide S receptor binds neuropeptide S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046022", "species_10046026" ], "products": [ "species_10046028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067360", "ENSBTAT00000018290", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360" ] }, "reaction_10049699": { "compartment": "compartment_984", "id": "reaction_10049699", "reactome": "R-BTA-444879", "name": "Relaxin receptor 2 binds relaxin 2 and INSL3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049687", "species_10049695" ], "products": [ "species_10049697" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020135", "O77801", "ENSBTAT00000027848", "O77801", "ENSBTAT00000027848", "E1BKC2", "ENSBTAT00000020135" ] }, "reaction_10049683": { "compartment": "compartment_984", "id": "reaction_10049683", "reactome": "R-BTA-444848", "name": "Relaxin 3 receptor 1 binds relaxin 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046333", "species_10046329" ], "products": [ "species_10046335" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055041", "F1MEV7", "ENSBTAT00000036249", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041" ] }, "reaction_10045292": { "compartment": "compartment_984", "id": "reaction_10045292", "reactome": "R-BTA-374251", "name": "DARC is a non-specific receptor for many chemokines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045284", "species_10045288" ], "products": [ "species_10045290" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004179", "ENSBTAT00000026275", "P79255", "ENSBTAT00000026275", "F1N018", "ENSBTAT00000004179" ] }, "reaction_10045324": { "compartment": "compartment_984", "id": "reaction_10045324", "reactome": "R-BTA-374298", "name": "Opioid receptors bind opioid peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045302", "species_10045320" ], "products": [ "species_10045322" ], "modifiers": [], "additional_components": [ "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209" ] }, "reaction_10046735": { "compartment": "compartment_984", "id": "reaction_10046735", "reactome": "R-BTA-388560", "name": "Endothelin receptors bind endothelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045876", "species_10045886" ], "products": [ "species_10045888" ], "modifiers": [], "additional_components": [ "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571" ] }, "reaction_10046915": { "compartment": "compartment_984", "id": "reaction_10046915", "reactome": "R-BTA-388863", "name": "Neuropeptide Y receptors can bind neuropeptide Y-related peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046293", "species_10046275" ], "products": [ "species_10046295" ], "modifiers": [], "additional_components": [ "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "ENSBTAT00000062944", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149" ] }, "reaction_10046917": { "compartment": "compartment_984", "id": "reaction_10046917", "reactome": "R-BTA-388900", "name": "Neurotensin receptors can bind neurotensins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045950", "species_10045960" ], "products": [ "species_10045962" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006980", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980" ] }, "reaction_10049637": { "compartment": "compartment_984", "id": "reaction_10049637", "reactome": "R-BTA-444498", "name": "Thyrotropin-releasing hormone receptor binds thyrotropin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046006", "species_10046002" ], "products": [ "species_10046018" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006982", "ENSBTAT00000026634", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982" ] }, "reaction_10046919": { "compartment": "compartment_984", "id": "reaction_10046919", "reactome": "R-BTA-388981", "name": "The Kiss receptor GPR54 binds kisspeptin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045902", "species_10045898" ], "products": [ "species_10045904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028248", "ENSBTAT00000073562", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248" ] }, "reaction_10045350": { "compartment": "compartment_984", "id": "reaction_10045350", "reactome": "R-BTA-374337", "name": "Apelin receptor binds to apelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045346", "species_10045336" ], "products": [ "species_10045348" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039541", "ENSBTAT00000026630", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541" ] }, "reaction_10047864": { "compartment": "compartment_984", "id": "reaction_10047864", "reactome": "R-BTA-417890", "name": "P2Y5 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045826", "species_417891" ], "products": [ "species_10045828" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008730", "species_417891", "A6QL49", "ENSBTAT00000008730" ] }, "reaction_10047851": { "compartment": "compartment_984", "id": "reaction_10047851", "reactome": "R-BTA-417820", "name": "P2Y9 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045838", "species_417891" ], "products": [ "species_10045840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004269", "species_417891", "A4IFV1", "ENSBTAT00000004269" ] }, "reaction_10047866": { "compartment": "compartment_984", "id": "reaction_10047866", "reactome": "R-BTA-417896", "name": "P2Y6 receptor can bind to UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417888", "species_10045832" ], "products": [ "species_10045834" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057184", "F1MTB2", "ENSBTAT00000057184", "species_205687" ] }, "reaction_10047853": { "compartment": "compartment_984", "id": "reaction_10047853", "reactome": "R-BTA-417825", "name": "P2Y11 receptor can bind to ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114570", "species_10045976" ], "products": [ "species_10045978" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018000", "F1MU50", "ENSBTAT00000018000", "species_113592" ] }, "reaction_10047868": { "compartment": "compartment_984", "id": "reaction_10047868", "reactome": "R-BTA-417898", "name": "P2Y4 receptor can bind to UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046215", "species_417877" ], "products": [ "species_10046217" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054975", "species_29494", "F1MDW9", "ENSBTAT00000054975" ] }, "reaction_10090956": { "compartment": "compartment_984", "id": "reaction_10090956", "reactome": "R-BTA-9611277", "name": "P2RY12 antagonists bind P2RY12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9611319", "species_10046221" ], "products": [ "species_10047855" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047870": { "compartment": "compartment_984", "id": "reaction_10047870", "reactome": "R-BTA-417908", "name": "P2RY1 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10045820" ], "products": [ "species_10045822" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001919", "species_29370", "P48042", "ENSBTAT00000001919" ] }, "reaction_10047857": { "compartment": "compartment_984", "id": "reaction_10047857", "reactome": "R-BTA-417829", "name": "P2RY12 binds ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114564", "species_10046221" ], "products": [ "species_10046223" ], "modifiers": [ [ "species_10047855", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000064076", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q0IIL0", "ENSBTAT00000064076" ] }, "reaction_10047989": { "compartment": "compartment_984", "id": "reaction_10047989", "reactome": "R-BTA-418918", "name": "The UDP/CysLT (P2Y17) receptor can bind UTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045892", "species_417888" ], "products": [ "species_10045894" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008214", "species_205687", "A2VEA2", "ENSBTAT00000008214" ] }, "reaction_10047860": { "compartment": "compartment_984", "id": "reaction_10047860", "reactome": "R-BTA-417842", "name": "P2Y10 receptor can bind to LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045844", "species_417891" ], "products": [ "species_10045846" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011278", "species_417891", "G3X6Q0", "ENSBTAT00000011278" ] }, "reaction_10047862": { "compartment": "compartment_984", "id": "reaction_10047862", "reactome": "R-BTA-417858", "name": "P2Y14 receptor can bind to UDP-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046227", "species_417855" ], "products": [ "species_10046229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027950", "species_29410", "Q3SX17", "ENSBTAT00000027950" ] }, "reaction_10047987": { "compartment": "compartment_984", "id": "reaction_10047987", "reactome": "R-BTA-418904", "name": "A1 and A3 receptors bind adenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046239", "species_83908" ], "products": [ "species_10046241" ], "modifiers": [], "additional_components": [ "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690" ] }, "reaction_10048003": { "compartment": "compartment_984", "id": "reaction_10048003", "reactome": "R-BTA-418925", "name": "ADORA2A,B bind Ade-Rib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047999", "species_83908" ], "products": [ "species_10048001" ], "modifiers": [], "additional_components": [ "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466" ] }, "reaction_10078536": { "compartment": "compartment_876", "id": "reaction_10078536", "reactome": "R-BTA-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_417891" ], "products": [ "species_109277", "species_6797635" ], "modifiers": [ [ "species_10078533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025329" ] }, "reaction_10048176": { "compartment": "compartment_984", "id": "reaction_10048176", "reactome": "R-BTA-419389", "name": "LPA-binding receptors bind LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045922", "species_417891" ], "products": [ "species_10045924" ], "modifiers": [], "additional_components": [ "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152" ] }, "reaction_10048180": { "compartment": "compartment_984", "id": "reaction_10048180", "reactome": "R-BTA-419428", "name": "S1PR2-5 bind S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_10046319" ], "products": [ "species_10046321" ], "modifiers": [], "additional_components": [ "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305" ] }, "reaction_10049663": { "compartment": "compartment_984", "id": "reaction_10049663", "reactome": "R-BTA-444731", "name": "GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10046074" ], "products": [ "species_10046076" ], "modifiers": [], "additional_components": [ "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529" ] }, "reaction_10084702": { "compartment": "compartment_984", "id": "reaction_10084702", "reactome": "R-BTA-8862700", "name": "CMKLR1 binds Resolvin E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023982", "species_10084698" ], "products": [ "species_10084700" ], "modifiers": [], "additional_components": [ "CHEBI:81559", "species_9022660", "ENSBTAT00000029488", "B9VR26", "ENSBTAT00000029488", "CHEBI:81559", "species_9022660" ] }, "reaction_10051217": { "compartment": "compartment_984", "id": "reaction_10051217", "reactome": "R-BTA-517536", "name": "N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_517533", "species_10046339" ], "products": [ "species_10046341" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007469", "Q3T0E9", "ENSBTAT00000007469", "species_517533" ] }, "reaction_10048178": { "compartment": "compartment_984", "id": "reaction_10048178", "reactome": "R-BTA-419426", "name": "Cannabinoid receptors can bind cannabinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444560", "species_10046255" ], "products": [ "species_10046257" ], "modifiers": [], "additional_components": [ "species_5693754", "species_426030", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030" ] }, "reaction_10053333": { "compartment": "compartment_984", "id": "reaction_10053333", "reactome": "R-BTA-964773", "name": "OXGR1 binds 2OG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_561075", "species_10046447" ], "products": [ "species_10046449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035454", "F1MYN3", "ENSBTAT00000035454", "species_113594" ] }, "reaction_10067350": { "compartment": "compartment_876", "id": "reaction_10067350", "reactome": "R-BTA-3296244", "name": "SUCNR1 binds SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433123", "species_10046441" ], "products": [ "species_10046443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068791", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536" ] }, "reaction_10049641": { "compartment": "compartment_984", "id": "reaction_10049641", "reactome": "R-BTA-444572", "name": "Zinc is an agonist of GPR39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046134", "species_158417" ], "products": [ "species_10046136" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065884", "species_29426", "G3MWJ9", "ENSBTAT00000065884" ] }, "reaction_10048172": { "compartment": "compartment_984", "id": "reaction_10048172", "reactome": "R-BTA-419334", "name": "Melatonin receptors can bind melatonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419339", "species_10046269" ], "products": [ "species_10046271" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068939", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339" ] }, "reaction_10081580": { "compartment": "compartment_984", "id": "reaction_10081580", "reactome": "R-BTA-6805205", "name": "GPR35 binds kynurenic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6805204", "species_10081576" ], "products": [ "species_10081578" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021281", "F1N600", "ENSBTAT00000021281", "species_6805204" ] }, "reaction_10067362": { "compartment": "compartment_876", "id": "reaction_10067362", "reactome": "R-BTA-3296309", "name": "HCAR3 binds HCAR3 ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3296330", "species_10046463" ], "products": [ "species_10046465" ], "modifiers": [], "additional_components": [ "CHEBI:37098", "species_197230", "ENSBTAT00000065393", "G3N168", "ENSBTAT00000065393", "CHEBI:37098", "species_197230" ] }, "reaction_10067364": { "compartment": "compartment_876", "id": "reaction_10067364", "reactome": "R-BTA-3296326", "name": "HCAR1 binds LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046453", "species_373863" ], "products": [ "species_10046455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001202", "species_373863", "B9UM28", "ENSBTAT00000001202" ] }, "reaction_10048174": { "compartment": "compartment_984", "id": "reaction_10048174", "reactome": "R-BTA-419351", "name": "PAF receptor binds platelet activating factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419375", "species_10045996" ], "products": [ "species_10045998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038757", "Q9TTY5", "ENSBTAT00000038757", "species_419375" ] }, "reaction_10083937": { "compartment": "compartment_984", "id": "reaction_10083937", "reactome": "R-BTA-8851679", "name": "GPR183 binds 7alpha,25-dihydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851675", "species_10046483" ], "products": [ "species_10046485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007471", "Q1RMI1", "ENSBTAT00000007471", "species_192184" ] }, "reaction_10049643": { "compartment": "compartment_984", "id": "reaction_10049643", "reactome": "R-BTA-444606", "name": "T1R2/T1R3 dimer is a sweet taste receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046501", "species_444679" ], "products": [ "species_10046503" ], "modifiers": [], "additional_components": [ "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207" ] }, "reaction_10045138": { "compartment": "compartment_984", "id": "reaction_10045138", "reactome": "R-BTA-373075", "name": "Metabotropic glutamate receptors bind glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382", "species_10045134" ], "products": [ "species_10045136" ], "modifiers": [], "additional_components": [ "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "F1MDE0", "ENSBTAT00000085376", "species_210382" ] }, "reaction_10067348": { "compartment": "compartment_876", "id": "reaction_10067348", "reactome": "R-BTA-3296233", "name": "T2Rs bind bitter-tasting compounds", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046435", "species_3296423" ], "products": [ "species_10046437" ], "modifiers": [], "additional_components": [ "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537" ] }, "reaction_10089211": { "compartment": "compartment_876", "id": "reaction_10089211", "reactome": "R-BTA-8982019", "name": "Active G alpha (i)i1/i2/i3 binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039640", "species_10089193" ], "products": [ "species_10089209" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089197": { "compartment": "compartment_876", "id": "reaction_10089197", "reactome": "R-BTA-8982012", "name": "G alpha (i):RGS dissociates to inactive G alpha (i)i1/i2/i3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089195" ], "products": [ "species_10039660", "species_10089193" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10088940": { "compartment": "compartment_876", "id": "reaction_10088940", "reactome": "R-BTA-8964242", "name": "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088932", "species_113592" ], "products": [ "species_29370", "species_10088937" ], "modifiers": [ [ "species_10088932", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088942": { "compartment": "compartment_70101", "id": "reaction_10088942", "reactome": "R-BTA-8964329", "name": "G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088937" ], "products": [ "species_10088935", "species_10039640" ], "modifiers": [], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10089214": { "compartment": "compartment_876", "id": "reaction_10089214", "reactome": "R-BTA-8982020", "name": "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089209" ], "products": [ "species_29372", "species_10089195" ], "modifiers": [ [ "species_10089209", "catalyst" ] ], "additional_components": [ "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "O46471", "ENSBTAT00000005642", "A0A3Q1MFC7", "ENSBTAT00000075674", "E1B7H3", "ENSBTAT00000037643", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MMH1", "ENSBTAT00000022048", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "P79348", "ENSBTAT00000004487", "E1BIV2", "ENSBTAT00000011200", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10048370": { "compartment": "compartment_70101", "id": "reaction_10048370", "reactome": "R-BTA-420883", "name": "Opsins act as GEFs for G alpha-t", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10048361" ], "products": [ "species_29420", "species_10048367" ], "modifiers": [ [ "species_10048206", "catalyst" ] ], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "P63212", "ENSBTAT00000003959", "species_29420", "P04695", "ENSBTAT00000023990", "P04695", "ENSBTAT00000023990", "species_29438", "P63212", "ENSBTAT00000003959", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777", "Q9BGI7", "ENSBTAT00000027054", "P02699", "ENSBTAT00000001730", "P51490", "ENSBTAT00000021912", "species_419777" ] }, "reaction_10037037": { "compartment": "compartment_70101", "id": "reaction_10037037", "reactome": "R-BTA-111962", "name": "PDE4A,C,D hydrolyse cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10037034", "catalyst" ] ], "additional_components": [ "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100" ] }, "reaction_10039658": { "compartment": "compartment_876", "id": "reaction_10039658", "reactome": "R-BTA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10036997" ], "products": [ "species_10039655" ], "modifiers": [ [ "species_10036997", "catalyst" ] ], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10039674": { "compartment": "compartment_876", "id": "reaction_10039674", "reactome": "R-BTA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039655" ], "products": [ "species_29372", "species_10039669" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039667": { "compartment": "compartment_876", "id": "reaction_10039667", "reactome": "R-BTA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592" ], "products": [ "species_111294", "species_30389" ], "modifiers": [ [ "species_10039655", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438" ] }, "reaction_10039671": { "compartment": "compartment_876", "id": "reaction_10039671", "reactome": "R-BTA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039669" ], "products": [ "species_10036997", "species_10039646" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420" ] }, "reaction_10036959": { "compartment": "compartment_70101", "id": "reaction_10036959", "reactome": "R-BTA-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10037045": { "compartment": "compartment_70101", "id": "reaction_10037045", "reactome": "R-BTA-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036956" ], "products": [ "species_29372", "species_10037043", "species_10036942" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "ENSBTAT00000074229" ] }, "reaction_10039676": { "compartment": "compartment_876", "id": "reaction_10039676", "reactome": "R-BTA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039662" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039664": { "compartment": "compartment_876", "id": "reaction_10039664", "reactome": "R-BTA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039662" ], "products": [ "species_10036997", "species_10039646", "species_10039660" ], "modifiers": [], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234" ] }, "reaction_10039651": { "compartment": "compartment_876", "id": "reaction_10039651", "reactome": "R-BTA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039644" ], "products": [ "species_29372", "species_10039648" ], "modifiers": [ [ "species_10039644", "catalyst" ] ], "additional_components": [ "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29420", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10039653": { "compartment": "compartment_876", "id": "reaction_10039653", "reactome": "R-BTA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039620", "species_10039642" ], "products": [ "species_10039644" ], "modifiers": [], "additional_components": [ "A0A3Q1M3D6", "ENSBTAT00000079386", "species_29438", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "A0A3Q1M3D6", "ENSBTAT00000079386" ] }, "reaction_10046534": { "compartment": "compartment_947587", "id": "reaction_10046534", "reactome": "R-BTA-380073", "name": "Liganded Gi-activating GPCR acts as a GEF for Gi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046509" ], "products": [ "species_29420", "species_10046513" ], "modifiers": [ [ "species_10046509", "catalyst" ], [ "species_10046532", "inhibitor" ] ], "additional_components": [ "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "CHEBI:32111", "species_188980", "species_5696361", "CHEBI:16296", "F1N5V2", "ENSBTAT00000038240", "A0A3Q1NND8", "ENSBTAT00000084207", "F1MY53", "ENSBTAT00000023519", "A0A452DII4", "ENSBTAT00000014782", "E1BP23", "ENSBTAT00000061371", "species_417891", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F6RDR3", "ENSBTAT00000020577", "A0A3S5ZP45", "ENSBTAT00000018066", "A0JN72", "ENSBTAT00000025880", "A0A3Q1M976", "ENSBTAT00000079349", "A0A452DJT3", "ENSBTAT00000026630", "A6QL98", "ENSBTAT00000039541", "CHEBI:3193", "species_76328", "CHEBI:3768", "CHEBI:10093", "CHEBI:17814", "species_40727", "CHEBI:8206", "CHEBI:48923", "CHEBI:28973", "CHEBI:73228", "CHEBI:23359", "CHEBI:28241", "CHEBI:73226", "CHEBI:73224", "CHEBI:65408", "CHEBI:3944", "CHEBI:73235", "CHEBI:73231", "CHEBI:16226", "CHEBI:27613", "CHEBI:5547", "CHEBI:2825", "CHEBI:73232", "CHEBI:18305", "CHEBI:3445", "CHEBI:36773", "CHEBI:2622", "CHEBI:73237", "CHEBI:2366", "CHEBI:3941", "CHEBI:7939", "CHEBI:351346", "CHEBI:8692", "CHEBI:73239", "CHEBI:15854", "CHEBI:9162", "CHEBI:26948", "CHEBI:50042", "CHEBI:69236", "CHEBI:73222", "CHEBI:17698", "CHEBI:73236", "CHEBI:2853", "F1MVK0", "ENSBTAT00000045470", "A0A3Q1N090", "ENSBTAT00000071230", "F1MP17", "ENSBTAT00000001761", "Q2ABB3", "ENSBTAT00000043009", "A0A3Q1LRA2", "ENSBTAT00000079249", "A0A3Q1N0Q7", "ENSBTAT00000082851", "F1MZD2", "ENSBTAT00000033179", "A0A3Q1ML22", "ENSBTAT00000071900", "F1N2G6", "ENSBTAT00000043010", "Q2ABB1", "ENSBTAT00000031637", "Q2ABC5", "ENSBTAT00000046105", "E1B8B7", "ENSBTAT00000055191", "Q2ABC4", "ENSBTAT00000022454", "Q2ABC0", "ENSBTAT00000042999", "A0A3Q1LZA1", "ENSBTAT00000076866", "A0A3Q1MIP5", "ENSBTAT00000071184", "Q2ABC3", "ENSBTAT00000024537", "F1MZ86", "ENSBTAT00000019846", "A6YT15", "ENSBTAT00000002036", "D9ZDE4", "ENSBTAT00000025420", "species_83909", "Q0VC81", "ENSBTAT00000010057", "P28190", "ENSBTAT00000072690", "F1MT56", "ENSBTAT00000037034", "Q8SQB1", "ENSBTAT00000028430", "A0A3Q1M1U4", "ENSBTAT00000068791", "species_113536", "F1MMU1", "ENSBTAT00000054307", "F1MB93", "ENSBTAT00000037840", "F6R5F6", "ENSBTAT00000052346", "F1MGM3", "ENSBTAT00000061041", "E1BGY8", "ENSBTAT00000003759", "species_209914", "species_373863", "B9UM28", "ENSBTAT00000001202", "species_159362", "F1N454", "ENSBTAT00000002768", "species_266074", "species_266013", "CHEBI:15650", "A2VEA2", "ENSBTAT00000008214", "Q1RMQ0", "ENSBTAT00000007331", "A4IF92", "ENSBTAT00000078248", "O62647", "ENSBTAT00000000695", "A0A3Q1LWC2", "ENSBTAT00000084136", "F1MYN3", "ENSBTAT00000035454", "species_113594", "F1ME98", "ENSBTAT00000000492", "F1MV28", "ENSBTAT00000004608", "A2VDV6", "ENSBTAT00000003550", "A6QR17", "ENSBTAT00000015111", "species_419305", "E1B9P2", "ENSBTAT00000025809", "A0A3Q1LGC0", "ENSBTAT00000067697", "species_5693754", "species_426030", "species_390899", "E1BBS2", "ENSBTAT00000048201", "F1MEV7", "ENSBTAT00000036249", "F1MSU3", "ENSBTAT00000055041", "A0A3Q1MJK4", "ENSBTAT00000068939", "species_419339", "G3N168", "ENSBTAT00000065393", "CHEBI:20067", "species_197230", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_416911", "A0A3Q1N2W9", "ENSBTAT00000066986", "E1BFV6", "ENSBTAT00000008645", "G3MWT4", "ENSBTAT00000011728", "F1MV99", "ENSBTAT00000052225", "G3N364", "ENSBTAT00000063299", "E1BAG6", "ENSBTAT00000047653", "E1BAB4", "ENSBTAT00000001415", "A0A3Q1LJN2", "ENSBTAT00000072365", "A5D7D8", "ENSBTAT00000025275", "E1B965", "ENSBTAT00000018119", "E1BLE8", "ENSBTAT00000017342", "species_210382", "Q3T0E9", "ENSBTAT00000007469", "species_517533", "species_372533", "P41985", "ENSBTAT00000019534", "CHEBI:37098", "Q2HJ17", "ENSBTAT00000010652", "F1MP16", "ENSBTAT00000001762", "A6QLA5", "ENSBTAT00000049352", "O97919", "ENSBTAT00000082438", "Q17QA1", "ENSBTAT00000009446", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "Q29RT9", "ENSBTAT00000024371", "Q5EA94", "ENSBTAT00000020855", "P01190", "ENSBTAT00000010386", "P01211", "ENSBTAT00000087134", "F1N083", "ENSBTAT00000004157", "Q2KIP6", "ENSBTAT00000001209", "species_29494", "F1MDW9", "ENSBTAT00000054975", "P51694", "ENSBTAT00000062944", "B1H0W3", "ENSBTAT00000022125", "F1MKB6", "ENSBTAT00000006247", "A6QQX6", "ENSBTAT00000057526", "Q1RMU8", "ENSBTAT00000087149", "Q1RMI1", "ENSBTAT00000007471", "species_192184", "species_29410", "Q3SX17", "ENSBTAT00000027950", "P25930", "ENSBTAT00000001406", "A4IF77", "ENSBTAT00000024512", "A0A3Q1M085", "ENSBTAT00000077980", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "G3N3U0", "ENSBTAT00000063808", "Q56JW7", "ENSBTAT00000011164", "A9QWP9", "ENSBTAT00000075648", "Q5MD61", "ENSBTAT00000019690", "G5E5J0", "ENSBTAT00000021510", "Q8MJV4", "ENSBTAT00000018455", "A0A3Q1LTH9", "ENSBTAT00000078382", "F1MCJ0", "ENSBTAT00000005326", "species_416428", "F1N1J4", "ENSBTAT00000019274", "species_3296298", "A0A452DKE4", "ENSBTAT00000048447", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "A0A3Q1MMQ2", "ENSBTAT00000081300", "A0A3Q1MKT3", "ENSBTAT00000078547" ] }, "reaction_10089224": { "compartment": "compartment_876", "id": "reaction_10089224", "reactome": "R-BTA-8982026", "name": "G alpha (q):RGS dissociates to inactive G alpha (q)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089219" ], "products": [ "species_10089199", "species_10037355" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420" ] }, "reaction_10047979": { "compartment": "compartment_876", "id": "reaction_10047979", "reactome": "R-BTA-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954" ], "products": [ "species_10037355" ], "modifiers": [ [ "species_10036954", "catalyst" ], [ "species_10047977", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "F1N7R3", "ENSBTAT00000005904" ] }, "reaction_10048632": { "compartment": "compartment_876", "id": "reaction_10048632", "reactome": "R-BTA-426209", "name": "DAG activation of TRPC channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048628", "species_114519" ], "products": [ "species_10048630" ], "modifiers": [], "additional_components": [ "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10048543": { "compartment": "compartment_70101", "id": "reaction_10048543", "reactome": "R-BTA-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519", "species_10048539" ], "products": [ "species_10048541" ], "modifiers": [], "additional_components": [ "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "F1MY82", "ENSBTAT00000004240", "A0A3Q1MRR6", "ENSBTAT00000078659", "E1BMG4", "ENSBTAT00000060978", "species_6797635" ] }, "reaction_10048587": { "compartment": "compartment_70101", "id": "reaction_10048587", "reactome": "R-BTA-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426030" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10048584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073448" ] }, "reaction_10048580": { "compartment": "compartment_876", "id": "reaction_10048580", "reactome": "R-BTA-426032", "name": "DAG is metabolized by DAGL to 2-AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114519" ], "products": [ "species_426026", "species_426030" ], "modifiers": [ [ "species_10048577", "catalyst" ] ], "additional_components": [ "E1BBV2", "ENSBTAT00000018523", "F6RA94", "ENSBTAT00000012173" ] }, "reaction_10076743": { "compartment": "compartment_876", "id": "reaction_10076743", "reactome": "R-BTA-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694509" ], "products": [ "species_422506", "species_70106", "species_76116" ], "modifiers": [ [ "species_10076740", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022100" ] }, "reaction_10048660": { "compartment": "compartment_70101", "id": "reaction_10048660", "reactome": "R-BTA-426240", "name": "DAG kinase produces phosphatidic acid from DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114519" ], "products": [ "species_76108", "species_29370" ], "modifiers": [ [ "species_10048657", "catalyst" ] ], "additional_components": [ "F1MCG9", "ENSBTAT00000031198", "A0A3Q1NJA6", "ENSBTAT00000066461", "E1BGA9", "ENSBTAT00000022905", "A0A3Q1LYT4", "ENSBTAT00000075621", "A0A3Q1N4W0", "ENSBTAT00000080144" ] }, "reaction_10037549": { "compartment": "compartment_876", "id": "reaction_10037549", "reactome": "R-BTA-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037544" ], "products": [ "species_10037546" ], "modifiers": [ [ "species_10036956", "catalyst" ] ], "additional_components": [ "species_6810412", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229", "species_6797635", "species_114520", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10047823": { "compartment": "compartment_70101", "id": "reaction_10047823", "reactome": "R-BTA-400586", "name": "G alpha (q) binds to Trio family RhoGEFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036954", "species_10047819" ], "products": [ "species_10047821" ], "modifiers": [], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "A0A3Q1N6F4", "ENSBTAT00000072165", "F1MLS2", "ENSBTAT00000061086", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10064910": { "compartment": "compartment_984", "id": "reaction_10064910", "reactome": "R-BTA-2179387", "name": "Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040221", "species_10040201" ], "products": [ "species_10064908" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029015", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10064915": { "compartment": "compartment_70101", "id": "reaction_10064915", "reactome": "R-BTA-2179407", "name": "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10064912", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10064919": { "compartment": "compartment_70101", "id": "reaction_10064919", "reactome": "R-BTA-2179415", "name": "GRB2:SOS1 binds to HBEGF:p-Y-EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10064908" ], "products": [ "species_10064912" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10089203": { "compartment": "compartment_876", "id": "reaction_10089203", "reactome": "R-BTA-8982017", "name": "Active G alpha (q) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089199", "species_10036954" ], "products": [ "species_10089201" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10046149": { "compartment": "compartment_70101", "id": "reaction_10046149", "reactome": "R-BTA-379048", "name": "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046140" ], "products": [ "species_29420", "species_10046142" ], "modifiers": [ [ "species_10046146", "catalyst" ] ], "additional_components": [ "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_209914", "A0A452DIJ2", "ENSBTAT00000017943", "F6QI78", "ENSBTAT00000052796", "A0A452DII4", "ENSBTAT00000014782", "A0A452DKE4", "ENSBTAT00000048447", "F1MU50", "ENSBTAT00000018000", "species_113592", "E1BEK2", "ENSBTAT00000040059", "species_419777", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "species_417891", "A4IFV1", "ENSBTAT00000004269", "A0A3Q1MXY0", "ENSBTAT00000073562", "E1BFS5", "ENSBTAT00000028248", "A0A3Q1MXN7", "ENSBTAT00000078035", "A0A140T8C8", "ENSBTAT00000053071", "P01175", "ENSBTAT00000010554", "P56449", "ENSBTAT00000026346", "G3X6Q0", "ENSBTAT00000011278", "Q8SPN1", "ENSBTAT00000021097", "F1MN36", "ENSBTAT00000013959", "F1MTB2", "ENSBTAT00000057184", "species_205687", "F1MWG2", "ENSBTAT00000028963", "E1BCZ7", "ENSBTAT00000004808", "P01156", "ENSBTAT00000006980", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "F1MJZ0", "ENSBTAT00000018290", "A0A3Q1MSN3", "ENSBTAT00000067360", "B5U8Y5", "ENSBTAT00000014446", "Q9BDJ6", "ENSBTAT00000016350", "species_372533", "F1MCK3", "ENSBTAT00000055896", "A0A452DI80", "ENSBTAT00000010601", "F1N5C5", "ENSBTAT00000015383", "P21450", "ENSBTAT00000018173", "P28088", "ENSBTAT00000070002", "P17322", "ENSBTAT00000010649", "Q867A9", "ENSBTAT00000028571", "O46639", "ENSBTAT00000026634", "A6QM11", "ENSBTAT00000006982", "A6QL49", "ENSBTAT00000008730", "P01272", "ENSBTAT00000000972", "A7MBH4", "ENSBTAT00000023275", "A2VEA2", "ENSBTAT00000008214", "F6PV87", "ENSBTAT00000009443", "F1ME85", "ENSBTAT00000022994", "A0A3Q1LXY0", "ENSBTAT00000076190", "species_29426", "G3MWJ9", "ENSBTAT00000065884", "F1N2X0", "ENSBTAT00000021612", "P08858", "ENSBTAT00000029067", "F1N2D2", "ENSBTAT00000026663", "E1BH62", "ENSBTAT00000013116", "G3X6J0", "ENSBTAT00000007420", "Q1JQB3", "ENSBTAT00000024480", "A7MB13", "ENSBTAT00000016931", "O46685", "ENSBTAT00000008858", "species_113529", "species_29370", "P48042", "ENSBTAT00000001919", "species_416436", "Q3T181", "ENSBTAT00000036478", "F1MRY8", "ENSBTAT00000054992", "CHEBI:28716", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560", "P32236", "ENSBTAT00000000559", "Q0VBW7", "ENSBTAT00000000188", "A0A3Q1M7J7", "ENSBTAT00000069568", "species_266074", "species_266013", "CHEBI:15650", "A5PKG3", "ENSBTAT00000034352", "species_391930", "F1MUY4", "ENSBTAT00000046806", "species_29460", "CHEBI:31011", "species_76179", "species_2022890", "CHEBI:30768", "B9VJW0", "ENSBTAT00000053502", "G5E581", "ENSBTAT00000008485", "species_8851314", "Q9TTY5", "ENSBTAT00000038757", "species_419375", "species_391932", "Q95125", "ENSBTAT00000019892", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "F1MCC4", "ENSBTAT00000012283", "F1N4J9", "ENSBTAT00000026902", "A4IFB7", "ENSBTAT00000001191", "CHEBI:17120", "B9VJV9", "ENSBTAT00000008619", "E1BLD8", "ENSBTAT00000071208", "F1MX11", "ENSBTAT00000004931", "Q3ZC80", "ENSBTAT00000005968", "A0A3Q1M9C6", "ENSBTAT00000087152", "F1MY53", "ENSBTAT00000023519", "E1BP23", "ENSBTAT00000061371", "species_210382", "F1MDE0", "ENSBTAT00000085376", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "species_266013", "A7MBH4", "ENSBTAT00000023275", "A5PKG3", "ENSBTAT00000034352" ] }, "reaction_10089222": { "compartment": "compartment_876", "id": "reaction_10089222", "reactome": "R-BTA-8982025", "name": "G alpha (q) in G (q):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089201" ], "products": [ "species_29372", "species_10089219" ], "modifiers": [ [ "species_10089201", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620", "species_29420", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "O46471", "ENSBTAT00000005642", "F1N3V3", "ENSBTAT00000026460", "E1BMB5", "ENSBTAT00000048654", "A7MBG6", "ENSBTAT00000012221", "F1MUR0", "ENSBTAT00000028880", "F1N7R3", "ENSBTAT00000005904", "A0A3Q1N2W6", "ENSBTAT00000070104", "E1BH23", "ENSBTAT00000054620" ] }, "reaction_10047947": { "compartment": "compartment_70101", "id": "reaction_10047947", "reactome": "R-BTA-418553", "name": "cAMP degradation by Phosphodiesterases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10047944", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N6Q5", "ENSBTAT00000072751", "F1N5T6", "ENSBTAT00000014100", "A0A3Q1M3R2", "ENSBTAT00000085287", "A0A3Q1M5L1", "ENSBTAT00000082666" ] }, "reaction_10089226": { "compartment": "compartment_876", "id": "reaction_10089226", "reactome": "R-BTA-8982641", "name": "ADRB2:GRK complex dissociates to Phosphorylated ADRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083948" ], "products": [ "species_10083941", "species_10084012" ], "modifiers": [], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789" ] }, "reaction_10089228": { "compartment": "compartment_876", "id": "reaction_10089228", "reactome": "R-BTA-8982645", "name": "GRKs bind ADRB2:Catecholamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083941", "species_10051595" ], "products": [ "species_10083943" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10091247": { "compartment": "compartment_70101", "id": "reaction_10091247", "reactome": "R-BTA-9629675", "name": "PDE3A hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10091244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072849" ] }, "reaction_10083951": { "compartment": "compartment_876", "id": "reaction_10083951", "reactome": "R-BTA-8851797", "name": "ADRB2 in ADRB2:GRK complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083943", "species_113592" ], "products": [ "species_29370", "species_10083948" ], "modifiers": [ [ "species_10083943", "catalyst" ] ], "additional_components": [ "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "E1BP29", "ENSBTAT00000061163" ] }, "reaction_10084016": { "compartment": "compartment_70101", "id": "reaction_10084016", "reactome": "R-BTA-8852167", "name": "ADRB2:Catecholamine binds ARRB1, ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10084012" ], "products": [ "species_10084014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092055": { "compartment": "compartment_70101", "id": "reaction_10092055", "reactome": "R-BTA-9705507", "name": "PDE3B hydrolyses cAMP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30389" ], "products": [ "species_76577" ], "modifiers": [ [ "species_10092052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006874" ] }, "reaction_10047498": { "compartment": "compartment_70101", "id": "reaction_10047498", "reactome": "R-BTA-392300", "name": "G beta:gamma activated PI3Kgamma converts PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047495", "catalyst" ] ], "additional_components": [ "P63212", "ENSBTAT00000003959", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10043315": { "compartment": "compartment_876", "id": "reaction_10043315", "reactome": "R-BTA-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10037311" ], "products": [ "species_10043313" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005600", "P61585", "ENSBTAT00000005600", "species_179838" ] }, "reaction_10088962": { "compartment": "compartment_70101", "id": "reaction_10088962", "reactome": "R-BTA-8964619", "name": "PAK1 binds ARHGEF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047596", "species_10048105" ], "products": [ "species_10088960" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080749", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10051656": { "compartment": "compartment_70101", "id": "reaction_10051656", "reactome": "R-BTA-749453", "name": "Liganded Gz-activating GPCR acts as a GEF for Gz", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051649" ], "products": [ "species_29420", "species_10051653" ], "modifiers": [ [ "species_10051649", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "P63212", "ENSBTAT00000003959" ] }, "reaction_10047468": { "compartment": "compartment_876", "id": "reaction_10047468", "reactome": "R-BTA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036997", "species_10047464" ], "products": [ "species_10047466" ], "modifiers": [], "additional_components": [ "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29926", "A0A3Q1MA58", "ENSBTAT00000080069", "E1B9K3", "ENSBTAT00000069484", "E1BM79", "ENSBTAT00000073752" ] }, "reaction_10089167": { "compartment": "compartment_876", "id": "reaction_10089167", "reactome": "R-BTA-8981892", "name": "Active G alpha (z) binds RGS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089163", "species_10047464" ], "products": [ "species_10089165" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089217": { "compartment": "compartment_876", "id": "reaction_10089217", "reactome": "R-BTA-8982021", "name": "G alpha (z) in G alpha (z):RGS complex is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089165" ], "products": [ "species_29372", "species_10089205" ], "modifiers": [ [ "species_10089165", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29438", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10089207": { "compartment": "compartment_876", "id": "reaction_10089207", "reactome": "R-BTA-8982018", "name": "G alpha (z):RGS complex dissociates to give inactive G alpha (z)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089205" ], "products": [ "species_10051645", "species_10089163" ], "modifiers": [], "additional_components": [ "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "species_29420", "A0A3Q1MM27", "ENSBTAT00000074311", "O46471", "ENSBTAT00000005642", "A7MBG6", "ENSBTAT00000012221", "P79348", "ENSBTAT00000004487" ] }, "reaction_10048170": { "compartment": "compartment_70101", "id": "reaction_10048170", "reactome": "R-BTA-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047839" ], "products": [ "species_29420", "species_10047841" ], "modifiers": [ [ "species_10048167", "catalyst" ] ], "additional_components": [ "species_29420", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "Q1RMJ6", "ENSBTAT00000018998", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LUW4", "ENSBTAT00000069851", "E1B9G8", "ENSBTAT00000014311", "A0A3Q1MRV3", "ENSBTAT00000083879", "A0A3Q1M8D9", "ENSBTAT00000071999", "E1BQ24", "ENSBTAT00000007450", "A0A3Q1MN47", "ENSBTAT00000081099", "A0A3Q1LQ45", "ENSBTAT00000078928", "A0A3Q1LNE2", "ENSBTAT00000077218", "A0A3Q1LJS1", "ENSBTAT00000068893", "A0A3Q1MA97", "ENSBTAT00000081198", "A0A3Q1MQP9", "ENSBTAT00000086853", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1N5A2", "ENSBTAT00000067575", "A0A3Q1LXW7", "ENSBTAT00000081961", "A0A3Q1MA22", "ENSBTAT00000069238", "Q08DA6", "ENSBTAT00000011773", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417", "F1N7C3", "ENSBTAT00000015471", "A0A3Q1MA88", "ENSBTAT00000069507", "Q58CS5", "ENSBTAT00000009131", "A0A3Q1MD11", "ENSBTAT00000081804", "F1MLS2", "ENSBTAT00000061086", "F1N2G5", "ENSBTAT00000002373", "A0A3Q1N5H1", "ENSBTAT00000068004" ] }, "reaction_10047552": { "compartment": "compartment_70101", "id": "reaction_10047552", "reactome": "R-BTA-398184", "name": "LARG activation by G alpha 12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047548", "species_10047544" ], "products": [ "species_10047550" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081099", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "A0A3Q1MN47", "ENSBTAT00000081099" ] }, "reaction_10051667": { "compartment": "compartment_70101", "id": "reaction_10051667", "reactome": "R-BTA-751029", "name": "Liganded G12/13-activating GPCR acts as a GEF for G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10051664" ], "products": [ "species_29420", "species_10051660" ], "modifiers": [ [ "species_10051664", "catalyst" ] ], "additional_components": [ "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892", "E1B7W0", "ENSBTAT00000025981", "F1MGA6", "ENSBTAT00000055443", "CHEBI:28918", "species_209789", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10037330": { "compartment": "compartment_70101", "id": "reaction_10037330", "reactome": "R-BTA-114544", "name": "p115-RhoGEF activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10037327", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10037332": { "compartment": "compartment_70101", "id": "reaction_10037332", "reactome": "R-BTA-114548", "name": "G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037325", "species_10037321" ], "products": [ "species_10037327" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066417", "G5E6P3", "ENSBTAT00000062941", "species_29438", "G5E6P3", "ENSBTAT00000062941", "species_29438", "A0A3Q1LFQ5", "ENSBTAT00000066417" ] }, "reaction_10047956": { "compartment": "compartment_876", "id": "reaction_10047956", "reactome": "R-BTA-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047544" ], "products": [ "species_10047953" ], "modifiers": [ [ "species_10047544", "catalyst" ] ], "additional_components": [ "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757", "species_29420", "E1BIL1", "ENSBTAT00000023757", "G5E6P3", "ENSBTAT00000062941", "G5E6P3", "ENSBTAT00000062941", "species_29438", "E1BIL1", "ENSBTAT00000023757" ] }, "reaction_10072123": { "compartment": "compartment_5263228", "id": "reaction_10072123", "reactome": "R-BTA-5610733", "name": "KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072119", "species_10072115" ], "products": [ "species_10072121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075908", "species_29438", "species_29420", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908" ] }, "reaction_10072154": { "compartment": "compartment_24337", "id": "reaction_10072154", "reactome": "R-BTA-5610763", "name": "PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072144" ], "products": [ "species_10072148" ], "modifiers": [ [ "species_10072152", "inhibitor" ] ], "additional_components": [ "E1BE57", "ENSBTAT00000017670", "E1BE57", "ENSBTAT00000017670", "ENSBTAT00000064817" ] }, "reaction_10072220": { "compartment": "compartment_5263228", "id": "reaction_10072220", "reactome": "R-BTA-5610767", "name": "The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072218", "catalyst" ], [ "species_10072121", "catalyst" ], [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BKE3", "ENSBTAT00000035821", "A0A3Q1MNB3", "ENSBTAT00000078675", "Q32KR5", "ENSBTAT00000087155", "A0A452DIR3", "ENSBTAT00000007606", "species_29438", "species_29420", "A0A3Q1LM07", "ENSBTAT00000075908", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308" ] }, "reaction_10072081": { "compartment": "compartment_70101", "id": "reaction_10072081", "reactome": "R-BTA-5610723", "name": "GLI proteins bind SUFU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072077", "species_10072073" ], "products": [ "species_10072079" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810" ] }, "reaction_10072138": { "compartment": "compartment_5263232", "id": "reaction_10072138", "reactome": "R-BTA-5610742", "name": "SCF(beta-TrCP) ubiquitinates p-GLI1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072130", "species_10033408" ], "products": [ "species_10072135" ], "modifiers": [ [ "species_10043873", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10072199": { "compartment": "compartment_5263232", "id": "reaction_10072199", "reactome": "R-BTA-5610766", "name": "The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072165" ], "products": [ "species_10072173" ], "modifiers": [ [ "species_10072197", "catalyst" ], [ "species_10072183", "catalyst" ], [ "species_10072187", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A0A3Q1MDV1", "ENSBTAT00000068810", "E1BBF8", "ENSBTAT00000025532", "F1MDL2", "ENSBTAT00000017038", "F6RVK1", "ENSBTAT00000049437", "A0A3Q1LTC8", "ENSBTAT00000082308", "ENSBTAT00000036487" ] }, "reaction_10072713": { "compartment": "compartment_7660", "id": "reaction_10072713", "reactome": "R-BTA-5635856", "name": "SPOP:CUL3:RBX1 ubiquitinates GLI2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072710", "species_10036828" ], "products": [ "species_10072708" ], "modifiers": [ [ "species_10072710", "catalyst" ] ], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q0VCW1", "ENSBTAT00000007660" ] }, "reaction_10072715": { "compartment": "compartment_5263228", "id": "reaction_10072715", "reactome": "R-BTA-5635860", "name": "GLI:SUFU translocates to the ciliary tip in response to Hh signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072079" ], "products": [ "species_10072165" ], "modifiers": [ [ "species_10072119", "catalyst" ] ], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "A0A3Q1MDV1", "ENSBTAT00000068810", "ENSBTAT00000075908" ] }, "reaction_10072685": { "compartment": "compartment_7660", "id": "reaction_10072685", "reactome": "R-BTA-5635845", "name": "GLI proteins bind CDC73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072669", "species_10072681" ], "products": [ "species_10072683" ], "modifiers": [], "additional_components": [ "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510", "ENSBTAT00000022205", "E1BPQ8", "ENSBTAT00000022205", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10072606": { "compartment": "compartment_261122", "id": "reaction_10072606", "reactome": "R-BTA-5632677", "name": "PTCH is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072602" ], "products": [ "species_10072604" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064817", "ENSBTAT00000064817" ] }, "reaction_10072720": { "compartment": "compartment_261122", "id": "reaction_10072720", "reactome": "R-BTA-5635865", "name": "SMURF1/2 dissociates from ub-PTCH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072718" ], "products": [ "species_10042973", "species_10072602" ], "modifiers": [], "additional_components": [ "G3N1D5", "ENSBTAT00000064817", "F1MLS5", "ENSBTAT00000043725", "ENSBTAT00000043725", "ENSBTAT00000064817" ] }, "reaction_10072677": { "compartment": "compartment_5263228", "id": "reaction_10072677", "reactome": "R-BTA-5635843", "name": "GLI translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072675" ], "products": [ "species_10072663" ], "modifiers": [], "additional_components": [ "F1MCY1", "ENSBTAT00000015510", "A6H727", "ENSBTAT00000008704", "A6H727", "ENSBTAT00000008704", "F1MCY1", "ENSBTAT00000015510" ] }, "reaction_10074038": { "compartment": "compartment_876", "id": "reaction_10074038", "reactome": "R-BTA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074035", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MCQ7", "ENSBTAT00000029056", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LUE0", "ENSBTAT00000083788", "E1BAI2", "ENSBTAT00000018586", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BG59", "ENSBTAT00000029159", "A0A3Q1MPT9", "ENSBTAT00000086336", "A0A3Q1MD11", "ENSBTAT00000081804", "A0A3Q1M7J4", "ENSBTAT00000085129", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "F1MXH7", "ENSBTAT00000011947", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LK34", "ENSBTAT00000085850", "A0A3Q1MB14", "ENSBTAT00000040022", "P11052", "ENSBTAT00000002054", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A452DJB1", "ENSBTAT00000044847", "A0A452DHX3", "ENSBTAT00000003498", "F1N5N3", "ENSBTAT00000021391", "F1MP52", "ENSBTAT00000015112", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LSU3", "ENSBTAT00000068365", "species_6797635", "A0A3Q1N010", "ENSBTAT00000084300" ] }, "reaction_10091515": { "compartment": "compartment_876", "id": "reaction_10091515", "reactome": "R-BTA-9647994", "name": "RAS proteins are depalmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039726" ], "products": [ "species_8848337", "species_10091512" ], "modifiers": [ [ "species_10091502", "catalyst" ], [ "species_10091504", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091458": { "compartment": "compartment_12045", "id": "reaction_10091458", "reactome": "R-BTA-9647977", "name": "ICMT methylates S-Farn RAS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10091448" ], "products": [ "species_10091454", "species_71285" ], "modifiers": [ [ "species_10077880", "catalyst" ], [ "species_10091456", "inhibitor" ] ], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29426", "G3N1V4", "ENSBTAT00000064297", "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10091490": { "compartment": "compartment_20699", "id": "reaction_10091490", "reactome": "R-BTA-9647982", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091454", "species_200993" ], "products": [ "species_10091477", "species_76194" ], "modifiers": [ [ "species_10091487", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "Q5EA55", "ENSBTAT00000069302", "Q58DA8", "ENSBTAT00000075844" ] }, "reaction_10091506": { "compartment": "compartment_876", "id": "reaction_10091506", "reactome": "R-BTA-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10091502" ], "products": [ "species_10091504" ], "modifiers": [], "additional_components": [ "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957", "A0A3Q1M5Z8", "ENSBTAT00000081950", "A7MBG2", "ENSBTAT00000008957" ] }, "reaction_10091479": { "compartment": "compartment_876", "id": "reaction_10091479", "reactome": "R-BTA-9647980", "name": "mature RAS proteins translocate to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091477" ], "products": [ "species_10039726" ], "modifiers": [], "additional_components": [ "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897" ] }, "reaction_10091527": { "compartment": "compartment_876", "id": "reaction_10091527", "reactome": "R-BTA-9649733", "name": "mature p21 RAS binds GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10039726" ], "products": [ "species_10040312" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420" ] }, "reaction_10074088": { "compartment": "compartment_876", "id": "reaction_10074088", "reactome": "R-BTA-5672969", "name": "Phosphorylation of RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074042" ], "products": [ "species_29370", "species_10074065" ], "modifiers": [ [ "species_10074085", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073930": { "compartment": "compartment_70101", "id": "reaction_10073930", "reactome": "R-BTA-5672957", "name": "PP2A dephosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073919" ], "products": [ "species_10073927", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073917": { "compartment": "compartment_70101", "id": "reaction_10073917", "reactome": "R-BTA-5672951", "name": "Inactive RAFs bind YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073913" ], "products": [ "species_10073915" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073932": { "compartment": "compartment_70101", "id": "reaction_10073932", "reactome": "R-BTA-5672958", "name": "YWHAB dimer dissociates from KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073927" ], "products": [ "species_10037668", "species_10073925" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091548": { "compartment": "compartment_876", "id": "reaction_10091548", "reactome": "R-BTA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657579", "species_10074042" ], "products": [ "species_10074135" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10073921": { "compartment": "compartment_70101", "id": "reaction_10073921", "reactome": "R-BTA-5672954", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037668", "species_10073869" ], "products": [ "species_10073919" ], "modifiers": [], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10073904": { "compartment": "compartment_876", "id": "reaction_10073904", "reactome": "R-BTA-5672950", "name": "\"Activator\" RAF:YWHAB dimer binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10073896" ], "products": [ "species_10073898" ], "modifiers": [ [ "species_10073902", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000070853" ] }, "reaction_10073872": { "compartment": "compartment_70101", "id": "reaction_10073872", "reactome": "R-BTA-5672948", "name": "MARK3 phosphorylates KSR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_113592" ], "products": [ "species_29370", "species_10073869" ], "modifiers": [ [ "species_10073863", "catalyst" ] ], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074050": { "compartment": "compartment_876", "id": "reaction_10074050", "reactome": "R-BTA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073898", "species_10074040" ], "products": [ "species_10074042" ], "modifiers": [ [ "species_10074048", "inhibitor" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10073940": { "compartment": "compartment_70101", "id": "reaction_10073940", "reactome": "R-BTA-5672960", "name": "YWHAB dimer dissociates from dephosphorylated RAF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073938" ], "products": [ "species_10037668", "species_10073936" ], "modifiers": [], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10073942": { "compartment": "compartment_70101", "id": "reaction_10073942", "reactome": "R-BTA-5672961", "name": "PP2A dephosphorylates inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10073915" ], "products": [ "species_29372", "species_10073938" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10074184": { "compartment": "compartment_20699", "id": "reaction_10074184", "reactome": "R-BTA-5674140", "name": "PAQR3 binds inactive RAFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074180", "species_10073913" ], "products": [ "species_10074182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071243", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1M5M4", "ENSBTAT00000071243" ] }, "reaction_10074221": { "compartment": "compartment_876", "id": "reaction_10074221", "reactome": "R-BTA-5675417", "name": "PEBP1 binds activated RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074213", "species_10074217" ], "products": [ "species_10074219" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000024107", "P13696", "ENSBTAT00000024107", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10074156": { "compartment": "compartment_876", "id": "reaction_10074156", "reactome": "R-BTA-5674022", "name": "BRAP autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10074144" ], "products": [ "species_10074153" ], "modifiers": [ [ "species_10074144", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A6H716", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074238": { "compartment": "compartment_876", "id": "reaction_10074238", "reactome": "R-BTA-5675433", "name": "PP5 dephosphorylates RAF1 S338", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074213" ], "products": [ "species_29372", "species_10074225" ], "modifiers": [ [ "species_10074235", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000010538" ] }, "reaction_10074146": { "compartment": "compartment_876", "id": "reaction_10074146", "reactome": "R-BTA-5674018", "name": "BRAP binds RAS:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728", "species_10074046" ], "products": [ "species_10074144" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10074148": { "compartment": "compartment_70101", "id": "reaction_10074148", "reactome": "R-BTA-5674019", "name": "BRAP binds KSR1:MARK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073863", "species_10074046" ], "products": [ "species_10074048" ], "modifiers": [], "additional_components": [ "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "ENSBTAT00000001552", "A6H716", "ENSBTAT00000001552", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074231": { "compartment": "compartment_876", "id": "reaction_10074231", "reactome": "R-BTA-5675431", "name": "PP2A dephosphorylates RAF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10074225" ], "products": [ "species_10074229", "species_29372" ], "modifiers": [ [ "species_10041566", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962" ] }, "reaction_10091534": { "compartment": "compartment_876", "id": "reaction_10091534", "reactome": "R-BTA-9649736", "name": "RAS intrinsic GTPase activity hydrolyzes GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039728" ], "products": [ "species_10040312" ], "modifiers": [ [ "species_10039728", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091580": { "compartment": "compartment_876", "id": "reaction_10091580", "reactome": "R-BTA-9658253", "name": "RAS:GTP binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10039728" ], "products": [ "species_10091578" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10074137": { "compartment": "compartment_876", "id": "reaction_10074137", "reactome": "R-BTA-5672978", "name": "RAF phosphorylates MAP2K dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074123" ], "products": [ "species_10074114", "species_29370" ], "modifiers": [ [ "species_10074123", "catalyst" ], [ "species_10074125", "inhibitor" ], [ "species_10074135", "inhibitor" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A452DI16", "ENSBTAT00000006653", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10091576": { "compartment": "compartment_876", "id": "reaction_10091576", "reactome": "R-BTA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074118", "species_9657577" ], "products": [ "species_10091574" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074129": { "compartment": "compartment_876", "id": "reaction_10074129", "reactome": "R-BTA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_113592" ], "products": [ "species_10074118", "species_29370" ], "modifiers": [ [ "species_10074114", "catalyst" ], [ "species_10074127", "inhibitor" ], [ "species_10074121", "inhibitor" ], [ "species_10074125", "inhibitor" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091568": { "compartment": "compartment_876", "id": "reaction_10091568", "reactome": "R-BTA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9657567", "species_10074123" ], "products": [ "species_10074125" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10074176": { "compartment": "compartment_74700", "id": "reaction_10074176", "reactome": "R-BTA-5674130", "name": "MAP2Ks and MAPKs are phosphorylated at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074172" ], "products": [ "species_29370", "species_10074174" ], "modifiers": [], "additional_components": [ "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "A0A3Q1M353", "ENSBTAT00000086962", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "Q0VCN2", "ENSBTAT00000082130", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833" ] }, "reaction_10074195": { "compartment": "compartment_20699", "id": "reaction_10074195", "reactome": "R-BTA-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10074190" ], "products": [ "species_29370", "species_10074192" ], "modifiers": [ [ "species_10074190", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "E1BP15", "ENSBTAT00000060984" ] }, "reaction_10091570": { "compartment": "compartment_876", "id": "reaction_10091570", "reactome": "R-BTA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657570" ], "products": [ "species_10074127" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091572": { "compartment": "compartment_876", "id": "reaction_10091572", "reactome": "R-BTA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074114", "species_9657574" ], "products": [ "species_10074121" ], "modifiers": [], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "A0A3Q1LQP3", "ENSBTAT00000074936", "A0A3Q1M888", "ENSBTAT00000079194" ] }, "reaction_10091595": { "compartment": "compartment_876", "id": "reaction_10091595", "reactome": "R-BTA-9660557", "name": "RAS:GTP binds RAL GDS proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091591", "species_10091589" ], "products": [ "species_10091593" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1NAC7", "ENSBTAT00000076160", "A0A3Q1M6Z6", "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10091529": { "compartment": "compartment_876", "id": "reaction_10091529", "reactome": "R-BTA-9649735", "name": "Intrinsic nucleotide exchange on RAS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438" ] }, "reaction_10075256": { "compartment": "compartment_7660", "id": "reaction_10075256", "reactome": "R-BTA-5687120", "name": "p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075220" ], "products": [ "species_10075236", "species_10075202" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075260": { "compartment": "compartment_7660", "id": "reaction_10075260", "reactome": "R-BTA-5687123", "name": "p-S115 MAPKAPK5 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075208" ], "products": [ "species_10075258" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000012303" ] }, "reaction_10075262": { "compartment": "compartment_70101", "id": "reaction_10075262", "reactome": "R-BTA-5687126", "name": "p-S215 FOXO3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075234" ], "products": [ "species_10075226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920" ] }, "reaction_10075251": { "compartment": "compartment_70101", "id": "reaction_10075251", "reactome": "R-BTA-5687107", "name": "MAPK4,6 translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075241" ], "products": [ "species_10075249" ], "modifiers": [], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709" ] }, "reaction_10075218": { "compartment": "compartment_7660", "id": "reaction_10075218", "reactome": "R-BTA-5687091", "name": "p-S MAPK6,4 binds MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066851", "species_10075214" ], "products": [ "species_10075216" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075253": { "compartment": "compartment_7660", "id": "reaction_10075253", "reactome": "R-BTA-5687109", "name": "MAPK4,6 translocate to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075249" ], "products": [ "species_10075241" ], "modifiers": [ [ "species_10050265", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "ENSBTAT00000017629" ] }, "reaction_10075223": { "compartment": "compartment_7660", "id": "reaction_10075223", "reactome": "R-BTA-5687094", "name": "p-S MAPK6,4 phosphorylate MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075216" ], "products": [ "species_113582", "species_10075220" ], "modifiers": [ [ "species_10075216", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075916": { "compartment": "compartment_70101", "id": "reaction_10075916", "reactome": "R-BTA-5690250", "name": "p-T182-MAPKAPK5 phoshphorylates DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075904" ], "products": [ "species_29370", "species_10075913" ], "modifiers": [ [ "species_10075904", "catalyst" ] ], "additional_components": [ "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303", "F1MH23", "ENSBTAT00000012303", "Q3MI00", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10076193": { "compartment": "compartment_7660", "id": "reaction_10076193", "reactome": "R-BTA-5692749", "name": "CDC14A,B bind MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076189", "species_10076185" ], "products": [ "species_10076191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075652", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10075906": { "compartment": "compartment_70101", "id": "reaction_10075906", "reactome": "R-BTA-5690245", "name": "p-T182 MAPKAPK5 binds DNAJB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075236", "species_10067944" ], "products": [ "species_10075904" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012303", "ENSBTAT00000036270", "Q3MI00", "ENSBTAT00000036270", "F1MH23", "ENSBTAT00000012303" ] }, "reaction_10075205": { "compartment": "compartment_70101", "id": "reaction_10075205", "reactome": "R-BTA-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075194" ], "products": [ "species_10075202", "species_29370" ], "modifiers": [ [ "species_10047654", "catalyst" ] ], "additional_components": [ "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "F1MVV5", "ENSBTAT00000013073", "G5E577", "ENSBTAT00000007709", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10076229": { "compartment": "compartment_7660", "id": "reaction_10076229", "reactome": "R-BTA-5692779", "name": "p-S182 MAPKAPK5 phosphorylates FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10042661" ], "products": [ "species_113582", "species_10076226" ], "modifiers": [ [ "species_10066865", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127", "ENSBTAT00000012303" ] }, "reaction_10075239": { "compartment": "compartment_70101", "id": "reaction_10075239", "reactome": "R-BTA-5687101", "name": "p-T182 MAPKAPK5 phosphorylates FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075232" ], "products": [ "species_10075234", "species_29370" ], "modifiers": [ [ "species_10075236", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "ENSBTAT00000012303" ] }, "reaction_10076198": { "compartment": "compartment_7660", "id": "reaction_10076198", "reactome": "R-BTA-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076191" ], "products": [ "species_113550", "species_10076195" ], "modifiers": [ [ "species_10076191", "catalyst" ] ], "additional_components": [ "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652", "A0A3Q1MTC5", "ENSBTAT00000075652", "G5E577", "ENSBTAT00000007709", "G5E577", "ENSBTAT00000007709", "A0A3Q1MTC5", "ENSBTAT00000075652" ] }, "reaction_10039690": { "compartment": "compartment_74700", "id": "reaction_10039690", "reactome": "R-BTA-170964", "name": "FRS2 binds to active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039686", "species_10039684" ], "products": [ "species_10039688" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090954": { "compartment": "compartment_74700", "id": "reaction_10090954", "reactome": "R-BTA-9610163", "name": "BRAF autophosphorylates downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090951", "species_113592" ], "products": [ "species_10090933", "species_29370" ], "modifiers": [ [ "species_10090951", "catalyst" ] ], "additional_components": [ "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "species_29426", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1M353", "ENSBTAT00000086962", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039711": { "compartment": "compartment_74700", "id": "reaction_10039711", "reactome": "R-BTA-170978", "name": "p-FRS2:CRKL binds C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039703", "species_10039707" ], "products": [ "species_10039709" ], "modifiers": [], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "ENSBTAT00000066818", "A0A3Q1LXN8", "ENSBTAT00000066818", "E1B7I9", "ENSBTAT00000025495", "G3N016", "ENSBTAT00000066024", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039697": { "compartment": "compartment_74700", "id": "reaction_10039697", "reactome": "R-BTA-170977", "name": "FRS2 is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039688" ], "products": [ "species_29370", "species_10039694" ], "modifiers": [ [ "species_10039688", "catalyst" ] ], "additional_components": [ "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10090944": { "compartment": "compartment_74700", "id": "reaction_10090944", "reactome": "R-BTA-9610153", "name": "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090935", "species_113592" ], "products": [ "species_29370", "species_10090937" ], "modifiers": [ [ "species_10090935", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10090949": { "compartment": "compartment_70101", "id": "reaction_10090949", "reactome": "R-BTA-9610156", "name": "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090937" ], "products": [ "species_10090946", "species_29370" ], "modifiers": [ [ "species_10090937", "catalyst" ] ], "additional_components": [ "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438", "Q0VD16", "ENSBTAT00000048212", "A0A3S5ZPX3", "ENSBTAT00000011377", "species_29426", "A0A3Q1M353", "ENSBTAT00000086962", "A0A140T894", "ENSBTAT00000022411", "P62833", "ENSBTAT00000068678", "species_29438" ] }, "reaction_10039592": { "compartment": "compartment_876", "id": "reaction_10039592", "reactome": "R-BTA-169904", "name": "C3G stimulates nucleotide exchange on Rap1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039587" ], "products": [ "species_10039589", "species_29420" ], "modifiers": [ [ "species_10039579", "catalyst" ] ], "additional_components": [ "P62833", "ENSBTAT00000068678", "species_29420", "P62833", "ENSBTAT00000068678", "species_29438", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039581": { "compartment": "compartment_984", "id": "reaction_10039581", "reactome": "R-BTA-169895", "name": "Crk's SH3 domain engages C3G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039579" ], "products": [ "species_10039579" ], "modifiers": [], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10039601": { "compartment": "compartment_876", "id": "reaction_10039601", "reactome": "R-BTA-169905", "name": "ARMS is phosphorylated by active TrkA receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039598" ], "products": [ "species_29370", "species_10039579" ], "modifiers": [ [ "species_10039598", "catalyst" ] ], "additional_components": [ "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924", "E1BQ32", "ENSBTAT00000007443", "A0A3Q1MJ18", "ENSBTAT00000067057", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10074879": { "compartment": "compartment_70101", "id": "reaction_10074879", "reactome": "R-BTA-5685366", "name": "GRB2-1:SOS1 binds p-Y-SHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073958", "species_10035491" ], "products": [ "species_10073960" ], "modifiers": [], "additional_components": [ "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N5N3", "ENSBTAT00000021391", "Q0IIE2", "ENSBTAT00000075224", "F1MP52", "ENSBTAT00000015112" ] }, "reaction_10039736": { "compartment": "compartment_876", "id": "reaction_10039736", "reactome": "R-BTA-170986", "name": "Ral-GDS binds to Ras-GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039732", "species_10039728" ], "products": [ "species_10039734" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087412", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1M6Z6", "ENSBTAT00000087412" ] }, "reaction_10040570": { "compartment": "compartment_70101", "id": "reaction_10040570", "reactome": "R-BTA-187688", "name": "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040546", "species_113592" ], "products": [ "species_10040551", "species_29370" ], "modifiers": [ [ "species_10040567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084476", "ENSBTAT00000084476", "species_29926", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10090994": { "compartment": "compartment_7660", "id": "reaction_10090994", "reactome": "R-BTA-9613213", "name": "NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090982", "species_10090978", "species_10090990" ], "products": [ "species_10090992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008295", "ENSBTAT00000019612", "G3N0C9", "ENSBTAT00000064240", "G3N0C9", "ENSBTAT00000064240", "F1N3F6", "ENSBTAT00000019612", "Q1RMU0", "ENSBTAT00000008295" ] }, "reaction_10041851": { "compartment": "compartment_947587", "id": "reaction_10041851", "reactome": "R-BTA-198266", "name": "PI3K produces PIP3 and other phosphatidyl inositides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10041848", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10041869": { "compartment": "compartment_947587", "id": "reaction_10041869", "reactome": "R-BTA-198315", "name": "Active IRS recruits PI3K to the plasma membrane and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10041865" ], "products": [ "species_10041867" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1MJ18", "ENSBTAT00000067057", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "A0A3Q1LP06", "ENSBTAT00000076924", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10041917": { "compartment": "compartment_7660", "id": "reaction_10041917", "reactome": "R-BTA-198714", "name": "ERK5 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041913" ], "products": [ "species_10041915" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001347", "ENSBTAT00000001347" ] }, "reaction_10040489": { "compartment": "compartment_17963", "id": "reaction_10040489", "reactome": "R-BTA-187020", "name": "Part of pro-beta-NGF is processed to mature beta-NGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040476" ], "products": [ "species_10040480" ], "modifiers": [ [ "species_10040486", "catalyst" ] ], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "species_74016", "A0A3Q1MCD7", "ENSBTAT00000077745" ] }, "reaction_10040495": { "compartment": "compartment_984", "id": "reaction_10040495", "reactome": "R-BTA-187035", "name": "Pro-beta-NGF and mature beta-NGF are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040480", "species_10040476" ], "products": [ "species_10039264", "species_10040493" ], "modifiers": [], "additional_components": [ "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924", "A0A3Q1LP06", "ENSBTAT00000076924" ] }, "reaction_10090722": { "compartment": "compartment_876", "id": "reaction_10090722", "reactome": "R-BTA-9603419", "name": "Activated NTRK3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090663", "species_10090411" ], "products": [ "species_10090720" ], "modifiers": [], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090727": { "compartment": "compartment_876", "id": "reaction_10090727", "reactome": "R-BTA-9603420", "name": "Activated NTRK3 promotes SRC autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090720" ], "products": [ "species_10090724", "species_29370" ], "modifiers": [ [ "species_10090720", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "E1BIM8", "ENSBTAT00000011767", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090666": { "compartment": "compartment_876", "id": "reaction_10090666", "reactome": "R-BTA-9034714", "name": "NTRK3 dimers trans-autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090654" ], "products": [ "species_10090663", "species_29370" ], "modifiers": [ [ "species_10090654", "catalyst" ] ], "additional_components": [ "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547" ] }, "reaction_10090675": { "compartment": "compartment_876", "id": "reaction_10090675", "reactome": "R-BTA-9034855", "name": "Activated PCLG1 dissociates from NTRK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090673" ], "products": [ "species_10090663", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "Q08DT3", "ENSBTAT00000013493", "G3N3T6", "ENSBTAT00000064547", "ENSBTAT00000023383" ] }, "reaction_10073244": { "compartment": "compartment_70101", "id": "reaction_10073244", "reactome": "R-BTA-5654730", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065269" ], "products": [ "species_10073210" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073215": { "compartment": "compartment_70101", "id": "reaction_10073215", "reactome": "R-BTA-5654679", "name": "CBL ubiquitinates FRS2 and FGFR3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073210" ], "products": [ "species_10073212" ], "modifiers": [ [ "species_10073210", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "G3XGD3", "ENSBTAT00000029946", "E1BJU2", "ENSBTAT00000008940", "F1MHC6", "ENSBTAT00000008839", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057337": { "compartment": "compartment_70101", "id": "reaction_10057337", "reactome": "R-BTA-1295632", "name": "PPA2A dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057334" ], "products": [ "species_10057300", "species_29372" ], "modifiers": [ [ "species_10057334", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057323": { "compartment": "compartment_70101", "id": "reaction_10057323", "reactome": "R-BTA-1295613", "name": "SPRY2 binds GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057316", "species_10035485" ], "products": [ "species_10057321" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10053082": { "compartment": "compartment_70101", "id": "reaction_10053082", "reactome": "R-BTA-934604", "name": "Phosphorylated SPRY2 is ubiquitinated by CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053077", "species_10033408" ], "products": [ "species_10053079" ], "modifiers": [ [ "species_10053077", "catalyst" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057327": { "compartment": "compartment_70101", "id": "reaction_10057327", "reactome": "R-BTA-1295621", "name": "CBL dissociates from ubiquitinated p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053079" ], "products": [ "species_10040359", "species_10057325" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10057329": { "compartment": "compartment_70101", "id": "reaction_10057329", "reactome": "R-BTA-1295622", "name": "SPRY2 binds CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10057316" ], "products": [ "species_10053062", "species_10053077" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057314": { "compartment": "compartment_70101", "id": "reaction_10057314", "reactome": "R-BTA-1295604", "name": "B-RAF dissociates from S111/S120 p-SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057312" ], "products": [ "species_10057310", "species_10057306" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1M353", "ENSBTAT00000086962", "ENSBTAT00000086962", "ENSBTAT00000002324" ] }, "reaction_10059156": { "compartment": "compartment_70101", "id": "reaction_10059156", "reactome": "R-BTA-1549564", "name": "PPTN11 dephosphorylates SPRY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057321" ], "products": [ "species_10057316", "species_10035485" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000006216", "ENSBTAT00000002653" ] }, "reaction_10057302": { "compartment": "compartment_70101", "id": "reaction_10057302", "reactome": "R-BTA-1295599", "name": "SPRY2 translocates to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057300" ], "products": [ "species_10053066" ], "modifiers": [], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10057318": { "compartment": "compartment_70101", "id": "reaction_10057318", "reactome": "R-BTA-1295609", "name": "SRC phosphorylates SPRY2 on Y55 and Y227", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10053066" ], "products": [ "species_10057316", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ], [ "species_10053072", "inhibitor" ] ], "additional_components": [ "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596", "ENSBTAT00000011767", "Q08E39", "ENSBTAT00000002324", "A0A3Q1MJ84", "ENSBTAT00000079589", "A0A3Q1MJY7", "ENSBTAT00000079589", "Q0P594", "ENSBTAT00000012182", "P67774", "ENSBTAT00000000596" ] }, "reaction_10040761": { "compartment": "compartment_984", "id": "reaction_10040761", "reactome": "R-BTA-190263", "name": "FGFR3b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040755", "species_10036461", "species_190915" ], "products": [ "species_10040759" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040779": { "compartment": "compartment_876", "id": "reaction_10040779", "reactome": "R-BTA-190385", "name": "Autocatalytic phosphorylation of FGFR3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040759", "species_113592" ], "products": [ "species_29370", "species_10036473" ], "modifiers": [ [ "species_10040759", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10083933": { "compartment": "compartment_17963", "id": "reaction_10083933", "reactome": "R-BTA-8851619", "name": "GALNT3 transfers GalNAc to FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10083928" ], "products": [ "species_205687", "species_10083930" ], "modifiers": [ [ "species_10052428", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940", "ENSBTAT00000018541" ] }, "reaction_10083935": { "compartment": "compartment_17963", "id": "reaction_10083935", "reactome": "R-BTA-8851632", "name": "GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083930" ], "products": [ "species_10036373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008940", "ENSBTAT00000008940" ] }, "reaction_10040782": { "compartment": "compartment_876", "id": "reaction_10040782", "reactome": "R-BTA-190388", "name": "Autocatalytic phosphorylation of FGFR3c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040751" ], "products": [ "species_10036485", "species_29370" ], "modifiers": [ [ "species_10040751", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10040753": { "compartment": "compartment_984", "id": "reaction_10040753", "reactome": "R-BTA-190261", "name": "FGFR3c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040747", "species_10036475", "species_190915" ], "products": [ "species_10040751" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086336", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1MPT9", "ENSBTAT00000086336" ] }, "reaction_10073240": { "compartment": "compartment_70101", "id": "reaction_10073240", "reactome": "R-BTA-5654717", "name": "FGFR4-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065247", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073192": { "compartment": "compartment_70101", "id": "reaction_10073192", "reactome": "R-BTA-5654669", "name": "Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073188", "species_10035515" ], "products": [ "species_10073190" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073237": { "compartment": "compartment_70101", "id": "reaction_10073237", "reactome": "R-BTA-5654714", "name": "FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10073190", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073177": { "compartment": "compartment_876", "id": "reaction_10073177", "reactome": "R-BTA-5654658", "name": "Activated FGFR4:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10073168" ], "products": [ "species_10073170" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073166": { "compartment": "compartment_876", "id": "reaction_10073166", "reactome": "R-BTA-5654653", "name": "Activated FGFR4 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073161" ], "products": [ "species_29370", "species_10073163" ], "modifiers": [ [ "species_10073161", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10073182": { "compartment": "compartment_70101", "id": "reaction_10073182", "reactome": "R-BTA-5654663", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073179", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073184": { "compartment": "compartment_70101", "id": "reaction_10073184", "reactome": "R-BTA-5654664", "name": "Activated FGFR4:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073168" ], "products": [ "species_10073179" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073028": { "compartment": "compartment_876", "id": "reaction_10073028", "reactome": "R-BTA-5654418", "name": "Activated FGFR4 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073023" ], "products": [ "species_29370", "species_10065243" ], "modifiers": [ [ "species_10073023", "catalyst" ], [ "species_10073026", "inhibitor" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073031": { "compartment": "compartment_70101", "id": "reaction_10073031", "reactome": "R-BTA-5654422", "name": "Activated FGFR4 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10065241" ], "products": [ "species_10073023" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10073175": { "compartment": "compartment_876", "id": "reaction_10073175", "reactome": "R-BTA-5654655", "name": "Activated FGFR4 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073170", "species_113592" ], "products": [ "species_10073172", "species_29370" ], "modifiers": [ [ "species_10073170", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087367": { "compartment": "compartment_70101", "id": "reaction_10087367", "reactome": "R-BTA-8941613", "name": "Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073172", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10072939": { "compartment": "compartment_876", "id": "reaction_10072939", "reactome": "R-BTA-5654169", "name": "p-4Y-PLCG1 dissociates from activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072924" ], "products": [ "species_10043237", "species_10065241" ], "modifiers": [], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10072927": { "compartment": "compartment_70101", "id": "reaction_10072927", "reactome": "R-BTA-5654151", "name": "Activated FGFR4 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072922" ], "products": [ "species_29370", "species_10072924" ], "modifiers": [ [ "species_10072922", "catalyst" ] ], "additional_components": [ "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10072933": { "compartment": "compartment_876", "id": "reaction_10072933", "reactome": "R-BTA-5654163", "name": "Activated FGFR4 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10061098", "species_10065241" ], "products": [ "species_10072922" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "F1MYF9", "ENSBTAT00000023383", "species_179838" ] }, "reaction_10073246": { "compartment": "compartment_70101", "id": "reaction_10073246", "reactome": "R-BTA-5654734", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10073186" ], "products": [ "species_10073217" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073222": { "compartment": "compartment_70101", "id": "reaction_10073222", "reactome": "R-BTA-5654684", "name": "CBL ubiquitinates FRS2 and FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073217" ], "products": [ "species_10073219" ], "modifiers": [ [ "species_10073217", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1B7I9", "ENSBTAT00000025495", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040776": { "compartment": "compartment_876", "id": "reaction_10040776", "reactome": "R-BTA-190326", "name": "Autocatalytic phosphorylation of FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040767" ], "products": [ "species_10036502", "species_29370" ], "modifiers": [ [ "species_10040767", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10040769": { "compartment": "compartment_984", "id": "reaction_10040769", "reactome": "R-BTA-190265", "name": "FGFR4 binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036500", "species_10040763", "species_190915" ], "products": [ "species_10040767" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BFP8", "ENSBTAT00000022973", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839" ] }, "reaction_10057704": { "compartment": "compartment_70101", "id": "reaction_10057704", "reactome": "R-BTA-1307955", "name": "FGFR4 binds HS:KLB:FGF19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036498", "species_10036506", "species_10040763", "species_190915" ], "products": [ "species_10057702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022973", "ENSBTAT00000019297", "ENSBTAT00000013942", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10057707": { "compartment": "compartment_876", "id": "reaction_10057707", "reactome": "R-BTA-1307963", "name": "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057702", "species_113592" ], "products": [ "species_29370", "species_10036508" ], "modifiers": [ [ "species_10057702", "catalyst" ] ], "additional_components": [ "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973", "F1N4S9", "ENSBTAT00000019297", "F1MN51", "ENSBTAT00000013942", "E1BFP8", "ENSBTAT00000022973", "species_190915", "F1MN51", "ENSBTAT00000013942", "F1N4S9", "ENSBTAT00000019297", "E1BFP8", "ENSBTAT00000022973" ] }, "reaction_10040720": { "compartment": "compartment_876", "id": "reaction_10040720", "reactome": "R-BTA-190258", "name": "FGFR2c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036438", "species_10040706", "species_190915" ], "products": [ "species_10040718" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "ENSBTAT00000072473", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040788": { "compartment": "compartment_876", "id": "reaction_10040788", "reactome": "R-BTA-190413", "name": "Autocatalytic phosphorylation of FGFR2c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040718" ], "products": [ "species_29370", "species_10036459" ], "modifiers": [ [ "species_10040718", "catalyst" ] ], "additional_components": [ "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10040744": { "compartment": "compartment_876", "id": "reaction_10040744", "reactome": "R-BTA-190260", "name": "FGFR2b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036405", "species_10040722", "species_190915" ], "products": [ "species_10040734" ], "modifiers": [ [ "species_190915", "catalyst" ], [ "species_10040742", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000072473", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10040785": { "compartment": "compartment_876", "id": "reaction_10040785", "reactome": "R-BTA-190408", "name": "Autocatalytic phosphorylation of FGFR2b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040734" ], "products": [ "species_29370", "species_10036432" ], "modifiers": [ [ "species_10040734", "catalyst" ] ], "additional_components": [ "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1LRU7", "ENSBTAT00000072473" ] }, "reaction_10073328": { "compartment": "compartment_984", "id": "reaction_10073328", "reactome": "R-BTA-5656070", "name": "FGFBPs bind FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040740", "species_10040736" ], "products": [ "species_10040742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044642", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q9MZ06", "ENSBTAT00000044642" ] }, "reaction_10072909": { "compartment": "compartment_70101", "id": "reaction_10072909", "reactome": "R-BTA-5654147", "name": "Activated FGFR2 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072904" ], "products": [ "species_29370", "species_10072906" ], "modifiers": [ [ "species_10072904", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072929": { "compartment": "compartment_876", "id": "reaction_10072929", "reactome": "R-BTA-5654157", "name": "p-4Y-PLCG1 dissociates from activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072906" ], "products": [ "species_10065255", "species_10043237" ], "modifiers": [], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383" ] }, "reaction_10072931": { "compartment": "compartment_876", "id": "reaction_10072931", "reactome": "R-BTA-5654159", "name": "Activated FGFR2 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_179838", "species_10061098" ], "products": [ "species_10072904" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "species_179838", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073001": { "compartment": "compartment_876", "id": "reaction_10073001", "reactome": "R-BTA-5654406", "name": "Activated FGFR2:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072988" ], "products": [ "species_10072990" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073004": { "compartment": "compartment_70101", "id": "reaction_10073004", "reactome": "R-BTA-5654407", "name": "Activated FGFR2 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072997", "species_113592" ], "products": [ "species_29370", "species_10072988" ], "modifiers": [ [ "species_10072997", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10072993": { "compartment": "compartment_70101", "id": "reaction_10072993", "reactome": "R-BTA-5654402", "name": "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072990", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072999": { "compartment": "compartment_70101", "id": "reaction_10072999", "reactome": "R-BTA-5654404", "name": "Activated FGFR2 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072995" ], "products": [ "species_10072997" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073129": { "compartment": "compartment_876", "id": "reaction_10073129", "reactome": "R-BTA-5654608", "name": "Activated FGFR2:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10065257" ], "products": [ "species_10073124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10087370": { "compartment": "compartment_70101", "id": "reaction_10087370", "reactome": "R-BTA-8941618", "name": "Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10065259", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073133": { "compartment": "compartment_70101", "id": "reaction_10073133", "reactome": "R-BTA-5654615", "name": "Activated FGFR2:pFRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065257" ], "products": [ "species_10073131" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072976": { "compartment": "compartment_876", "id": "reaction_10072976", "reactome": "R-BTA-5654397", "name": "Activated FGFR2 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072961" ], "products": [ "species_29370", "species_10065257" ], "modifiers": [ [ "species_10072961", "catalyst" ], [ "species_10072974", "inhibitor" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073136": { "compartment": "compartment_70101", "id": "reaction_10073136", "reactome": "R-BTA-5654618", "name": "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073131", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10072979": { "compartment": "compartment_70101", "id": "reaction_10072979", "reactome": "R-BTA-5654399", "name": "Activated FGFR2 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065255", "species_10072959" ], "products": [ "species_10072961" ], "modifiers": [], "additional_components": [ "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073127": { "compartment": "compartment_876", "id": "reaction_10073127", "reactome": "R-BTA-5654607", "name": "Activated FGFR2 phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073124", "species_113592" ], "products": [ "species_29370", "species_10065259" ], "modifiers": [ [ "species_10073124", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073231": { "compartment": "compartment_70101", "id": "reaction_10073231", "reactome": "R-BTA-5654697", "name": "FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065263", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073208": { "compartment": "compartment_70101", "id": "reaction_10073208", "reactome": "R-BTA-5654677", "name": "CBL ubiquitinates FRS2 and FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073203", "species_10033408" ], "products": [ "species_10073205" ], "modifiers": [ [ "species_10073203", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073242": { "compartment": "compartment_70101", "id": "reaction_10073242", "reactome": "R-BTA-5654729", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065259" ], "products": [ "species_10073203" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "species_190915", "A0A3Q1LRU7", "ENSBTAT00000072473", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "F1MHC6", "ENSBTAT00000008839", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1M3Q3", "ENSBTAT00000073054", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073071": { "compartment": "compartment_876", "id": "reaction_10073071", "reactome": "R-BTA-5654510", "name": "FGFRL1 binds SPRED1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073053", "species_10073067" ], "products": [ "species_10073069" ], "modifiers": [], "additional_components": [ "F1MQI5", "ENSBTAT00000039444", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "A0A3Q1MP99", "ENSBTAT00000068413", "F1MH60", "ENSBTAT00000046117", "F1MQI5", "ENSBTAT00000039444" ] }, "reaction_10073077": { "compartment": "compartment_876", "id": "reaction_10073077", "reactome": "R-BTA-5654511", "name": "FGFRL1 dimer binds FGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073073", "species_10073053", "species_190915" ], "products": [ "species_10073075" ], "modifiers": [], "additional_components": [ "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016", "F1MQI5", "ENSBTAT00000039444", "species_190915", "F1MQI5", "ENSBTAT00000039444", "G3XGD3", "ENSBTAT00000029946", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1NNL0", "ENSBTAT00000086016" ] }, "reaction_10073199": { "compartment": "compartment_70101", "id": "reaction_10073199", "reactome": "R-BTA-5654672", "name": "CBL ubiquitinates FRS2 and FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10073194" ], "products": [ "species_10073196" ], "modifiers": [ [ "species_10073194", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10073201": { "compartment": "compartment_70101", "id": "reaction_10073201", "reactome": "R-BTA-5654673", "name": "p-CBL:GRB2 binds p-FRS2:activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040423", "species_10065249" ], "products": [ "species_10073194" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040794": { "compartment": "compartment_876", "id": "reaction_10040794", "reactome": "R-BTA-190429", "name": "Autocatalytic phosphorylation of FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040702" ], "products": [ "species_29370", "species_10036379" ], "modifiers": [ [ "species_10040702", "catalyst" ] ], "additional_components": [ "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040704": { "compartment": "compartment_984", "id": "reaction_10040704", "reactome": "R-BTA-190256", "name": "FGFR1c binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036375", "species_10040698", "species_190915" ], "products": [ "species_10040702" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "ENSBTAT00000083788", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "P03968", "ENSBTAT00000078959", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001" ] }, "reaction_10040696": { "compartment": "compartment_984", "id": "reaction_10040696", "reactome": "R-BTA-190245", "name": "FGFR1b binds to FGF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040690", "species_190915", "species_10036328" ], "products": [ "species_10040694" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040791": { "compartment": "compartment_876", "id": "reaction_10040791", "reactome": "R-BTA-190427", "name": "Autocatalytic phosphorylation of FGFR1b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040694", "species_113592" ], "products": [ "species_29370", "species_10036344" ], "modifiers": [ [ "species_10040694", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040860": { "compartment": "compartment_876", "id": "reaction_10040860", "reactome": "R-BTA-191062", "name": "Autocatalytic phosphorylation of Klotho-bound FGFR1c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040771", "species_113592" ], "products": [ "species_29370", "species_10036399" ], "modifiers": [ [ "species_10040771", "catalyst" ] ], "additional_components": [ "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788", "A0A3Q1LUE0", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10040773": { "compartment": "compartment_984", "id": "reaction_10040773", "reactome": "R-BTA-190268", "name": "FGFR1c binds to Klotho-bound FGF23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036397", "species_10040698", "species_190915" ], "products": [ "species_10040771" ], "modifiers": [ [ "species_190915", "catalyst" ] ], "additional_components": [ "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "ENSBTAT00000083788", "species_190915", "E1BAI2", "ENSBTAT00000018586", "E1BJU2", "ENSBTAT00000008940", "A0A3Q1LUE0", "ENSBTAT00000083788" ] }, "reaction_10073097": { "compartment": "compartment_876", "id": "reaction_10073097", "reactome": "R-BTA-5654578", "name": "Activated FGFR1 phosphorylates FRS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073094", "species_113592" ], "products": [ "species_10072950", "species_29370" ], "modifiers": [ [ "species_10073094", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073113": { "compartment": "compartment_876", "id": "reaction_10073113", "reactome": "R-BTA-5654587", "name": "Activated FGFR1:p-FRS phosphorylates PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073104" ], "products": [ "species_10073110", "species_29370" ], "modifiers": [ [ "species_10073104", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073083": { "compartment": "compartment_70101", "id": "reaction_10073083", "reactome": "R-BTA-5654569", "name": "Activated FGFR1 binds FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10072959" ], "products": [ "species_10073079" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000025495", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072957": { "compartment": "compartment_70101", "id": "reaction_10072957", "reactome": "R-BTA-5654392", "name": "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10072954", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10087373": { "compartment": "compartment_70101", "id": "reaction_10087373", "reactome": "R-BTA-8941623", "name": "Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073110", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073090": { "compartment": "compartment_876", "id": "reaction_10073090", "reactome": "R-BTA-5654575", "name": "Activated FGFR1 phosphorylates FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073079", "species_113592" ], "products": [ "species_29370", "species_10065235" ], "modifiers": [ [ "species_10073079", "catalyst" ] ], "additional_components": [ "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073106": { "compartment": "compartment_876", "id": "reaction_10073106", "reactome": "R-BTA-5654584", "name": "Activated FGFR1:p-FRS bind to PPTN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10072952" ], "products": [ "species_10073104" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10073108": { "compartment": "compartment_70101", "id": "reaction_10073108", "reactome": "R-BTA-5654586", "name": "Activated FGFR1:p-FRS binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10072952" ], "products": [ "species_10072954" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073225": { "compartment": "compartment_70101", "id": "reaction_10073225", "reactome": "R-BTA-5654690", "name": "FGFR1-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065239", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073115": { "compartment": "compartment_70101", "id": "reaction_10073115", "reactome": "R-BTA-5654596", "name": "Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065251", "species_10035515" ], "products": [ "species_10065253" ], "modifiers": [], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073228": { "compartment": "compartment_70101", "id": "reaction_10073228", "reactome": "R-BTA-5654692", "name": "FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10065253", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "F1N339", "ENSBTAT00000002653", "E1B7I9", "ENSBTAT00000025495", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10073087": { "compartment": "compartment_70101", "id": "reaction_10073087", "reactome": "R-BTA-5654573", "name": "Activated FGFR1 binds SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072995", "species_10065233" ], "products": [ "species_10073085" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073119": { "compartment": "compartment_876", "id": "reaction_10073119", "reactome": "R-BTA-5654597", "name": "Activated FGFR1:p-SHC1 binds GRB2:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10073099" ], "products": [ "species_10073117" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073102": { "compartment": "compartment_70101", "id": "reaction_10073102", "reactome": "R-BTA-5654582", "name": "Activated FGFR1 phosphorylates SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10073085" ], "products": [ "species_29370", "species_10073099" ], "modifiers": [ [ "species_10073085", "catalyst" ] ], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10073122": { "compartment": "compartment_70101", "id": "reaction_10073122", "reactome": "R-BTA-5654600", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10073117", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10073326": { "compartment": "compartment_876", "id": "reaction_10073326", "reactome": "R-BTA-5656064", "name": "Activated FGFR1 binds FLRT1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065233", "species_10073322" ], "products": [ "species_10073324" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "F1N0R7", "ENSBTAT00000004298", "G3MY74", "ENSBTAT00000065908", "F1MVT1", "ENSBTAT00000028517", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10072937": { "compartment": "compartment_876", "id": "reaction_10072937", "reactome": "R-BTA-5654167", "name": "Activated FGFR1 binds PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10065233", "species_10061098" ], "products": [ "species_10072915" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072920": { "compartment": "compartment_70101", "id": "reaction_10072920", "reactome": "R-BTA-5654149", "name": "Activated FGFR1 phosphorylates PLCG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072915", "species_113592" ], "products": [ "species_10072917", "species_29370" ], "modifiers": [ [ "species_10072915", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "species_179838" ] }, "reaction_10072935": { "compartment": "compartment_876", "id": "reaction_10072935", "reactome": "R-BTA-5654165", "name": "p-4Y-PLCG1 dissociates from activated FGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072917" ], "products": [ "species_10043237", "species_10065233" ], "modifiers": [], "additional_components": [ "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "P03968", "ENSBTAT00000078959", "E1BGY3", "ENSBTAT00000011373", "A0A3Q1NAV6", "ENSBTAT00000086367", "A0A3Q1NNL0", "ENSBTAT00000086016", "species_190915", "A0A3Q1LUE0", "ENSBTAT00000083788", "D8KXU9", "ENSBTAT00000064356", "G3XGD3", "ENSBTAT00000029946", "G3MXR4", "ENSBTAT00000065993", "E1BHC1", "ENSBTAT00000016675", "E1BP37", "ENSBTAT00000061318", "E1BJU2", "ENSBTAT00000008940", "F1N6G8", "ENSBTAT00000002001", "E1BAI2", "ENSBTAT00000018586" ] }, "reaction_10091689": { "compartment": "compartment_876", "id": "reaction_10091689", "reactome": "R-BTA-9674095", "name": "PDGFRs bind type II TKI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9674079", "species_10040472" ], "products": [ "species_10091687" ], "modifiers": [], "additional_components": [ "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976", "A0A3Q1ME99", "ENSBTAT00000067659", "A0A3Q1N3Z8", "ENSBTAT00000086976" ] }, "reaction_10046666": { "compartment": "compartment_984", "id": "reaction_10046666", "reactome": "R-BTA-382057", "name": "Release of novel PDGFs as latent factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046658" ], "products": [ "species_10046664" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10046677": { "compartment": "compartment_984", "id": "reaction_10046677", "reactome": "R-BTA-382061", "name": "Extracellular processing of novel PDGFs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046664" ], "products": [ "species_10046672", "species_10046670" ], "modifiers": [ [ "species_10046674", "catalyst" ] ], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10046660": { "compartment": "compartment_20699", "id": "reaction_10046660", "reactome": "R-BTA-382053", "name": "Translocation of PDGF from ER to Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046654" ], "products": [ "species_10046658" ], "modifiers": [], "additional_components": [ "E1BJY4", "ENSBTAT00000061070", "E1BJY4", "ENSBTAT00000061070" ] }, "reaction_10057850": { "compartment": "compartment_876", "id": "reaction_10057850", "reactome": "R-BTA-1433454", "name": "Phosphorylation of GAB2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043813", "species_113592" ], "products": [ "species_10057847", "species_29370" ], "modifiers": [ [ "species_10043813", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533", "A0A3Q1M864", "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10057854": { "compartment": "compartment_876", "id": "reaction_10057854", "reactome": "R-BTA-1433456", "name": "Recruitment of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057840", "species_10046556" ], "products": [ "species_10057852" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057872": { "compartment": "compartment_876", "id": "reaction_10057872", "reactome": "R-BTA-1433514", "name": "Synthesis of PIP3 from PIP2 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057869", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "P32871", "ENSBTAT00000072391", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10058480": { "compartment": "compartment_876", "id": "reaction_10058480", "reactome": "R-BTA-1470012", "name": "Disassociation and translocation of STATs to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058476" ], "products": [ "species_10057840", "species_10052345" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10091667": { "compartment": "compartment_876", "id": "reaction_10091667", "reactome": "R-BTA-9669854", "name": "KIT binds type II TKIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9669722" ], "products": [ "species_10091665" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057845": { "compartment": "compartment_876", "id": "reaction_10057845", "reactome": "R-BTA-1433428", "name": "GRB2 is indirectly recruited to p-KIT through SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043807", "species_10035485" ], "products": [ "species_10043809" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10043832": { "compartment": "compartment_876", "id": "reaction_10043832", "reactome": "R-BTA-205244", "name": "Recruitment of CBL to KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10043828" ], "products": [ "species_10043830" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10057867": { "compartment": "compartment_876", "id": "reaction_10057867", "reactome": "R-BTA-1433506", "name": "Phosphorylation of APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057864" ], "products": [ "species_10043826", "species_29370" ], "modifiers": [ [ "species_10057864", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1MRH8", "ENSBTAT00000012781" ] }, "reaction_10058474": { "compartment": "compartment_876", "id": "reaction_10058474", "reactome": "R-BTA-1470009", "name": "Phosphorylation of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057852" ], "products": [ "species_10058471", "species_29370" ], "modifiers": [ [ "species_10057852", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10058478": { "compartment": "compartment_876", "id": "reaction_10058478", "reactome": "R-BTA-1470010", "name": "Dimerization of STATs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058471" ], "products": [ "species_10058476" ], "modifiers": [], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3Q1ME65", "ENSBTAT00000084342", "E1BCP6", "ENSBTAT00000015986", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1ME65", "ENSBTAT00000084342" ] }, "reaction_10057857": { "compartment": "compartment_876", "id": "reaction_10057857", "reactome": "R-BTA-1433471", "name": "Activation of RAS by p-KIT bound SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10043817", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A452DHX3", "ENSBTAT00000003498", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10043815": { "compartment": "compartment_876", "id": "reaction_10043815", "reactome": "R-BTA-205234", "name": "Indirect recruitment of GAB2 to p-KIT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10043809" ], "products": [ "species_10043813" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "Q3T0F9", "ENSBTAT00000006216", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10091751": { "compartment": "compartment_876", "id": "reaction_10091751", "reactome": "R-BTA-9681375", "name": "KIT binds ripretinib", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043782", "species_9674322" ], "products": [ "species_10091749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003498", "A0A452DHX3", "ENSBTAT00000003498" ] }, "reaction_10057862": { "compartment": "compartment_876", "id": "reaction_10057862", "reactome": "R-BTA-1433488", "name": "Phosphorylation of SHP2 by SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057859", "species_113592" ], "products": [ "species_29370", "species_10043807" ], "modifiers": [ [ "species_10057859", "catalyst" ] ], "additional_components": [ "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653", "A0A452DHX3", "ENSBTAT00000003498", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10041657": { "compartment": "compartment_876", "id": "reaction_10041657", "reactome": "R-BTA-195408", "name": "NRP-1 forms a ternary complex with VEGF165 and VEGFR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041653", "species_10041457" ], "products": [ "species_10041655" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026471", "ENSBTAT00000001038", "F1MWF1", "ENSBTAT00000001038", "E1BMX5", "ENSBTAT00000026471" ] }, "reaction_10041649": { "compartment": "compartment_984", "id": "reaction_10041649", "reactome": "R-BTA-195378", "name": "Homodimerization of VEGF proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041441" ], "products": [ "species_10041443" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019613", "Q9XS50", "ENSBTAT00000019613" ] }, "reaction_10070651": { "compartment": "compartment_876", "id": "reaction_10070651", "reactome": "R-BTA-5218820", "name": "Src kinases phosphorylate VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070647", "species_113592" ], "products": [ "species_29370", "species_10070649" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "species_179838", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070589": { "compartment": "compartment_876", "id": "reaction_10070589", "reactome": "R-BTA-5218640", "name": "SRC-1 phosphorylates p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070580", "species_113592" ], "products": [ "species_29370", "species_10070586" ], "modifiers": [ [ "species_10070580", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070657": { "compartment": "compartment_876", "id": "reaction_10070657", "reactome": "R-BTA-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070655" ], "products": [ "species_29370", "species_10070605" ], "modifiers": [ [ "species_10036594", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "ENSBTAT00000039221" ] }, "reaction_10070628": { "compartment": "compartment_70101", "id": "reaction_10070628", "reactome": "R-BTA-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070612", "species_112275", "species_74016" ], "products": [ "species_10070626" ], "modifiers": [], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_74016", "species_112275", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10070615": { "compartment": "compartment_70101", "id": "reaction_10070615", "reactome": "R-BTA-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070605" ], "products": [ "species_10070612", "species_29370" ], "modifiers": [ [ "species_10070605", "catalyst" ] ], "additional_components": [ "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1MSP9", "ENSBTAT00000070692", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10069535": { "compartment": "compartment_876", "id": "reaction_10069535", "reactome": "R-BTA-4420206", "name": "Phosphorylation of SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069530" ], "products": [ "species_29370", "species_10069532" ], "modifiers": [ [ "species_10069530", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071504": { "compartment": "compartment_876", "id": "reaction_10071504", "reactome": "R-BTA-5357429", "name": "AXL autophosphorylates on Y772 and Y814", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071501" ], "products": [ "species_29370", "species_10070638" ], "modifiers": [ [ "species_10071501", "catalyst" ] ], "additional_components": [ "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10071506": { "compartment": "compartment_876", "id": "reaction_10071506", "reactome": "R-BTA-5357432", "name": "AXL binds SRC-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069532", "species_10071499" ], "products": [ "species_10071501" ], "modifiers": [], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000075025", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10070645": { "compartment": "compartment_876", "id": "reaction_10070645", "reactome": "R-BTA-5218819", "name": "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10070642", "catalyst" ] ], "additional_components": [ "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10071508": { "compartment": "compartment_876", "id": "reaction_10071508", "reactome": "R-BTA-5357479", "name": "p-AXL binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10070638" ], "products": [ "species_10070640" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "F1MWF1", "ENSBTAT00000001038", "A7Z041", "ENSBTAT00000046702", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MRN2", "ENSBTAT00000075025", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10070676": { "compartment": "compartment_876", "id": "reaction_10070676", "reactome": "R-BTA-5218847", "name": "PAK2 binds NCK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047604", "species_10070672" ], "products": [ "species_10070674" ], "modifiers": [], "additional_components": [ "A0A3Q1M0G8", "ENSBTAT00000082239", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10070624": { "compartment": "compartment_876", "id": "reaction_10070624", "reactome": "R-BTA-5218806", "name": "FYN autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070619" ], "products": [ "species_29370", "species_10070621" ], "modifiers": [ [ "species_10070619", "catalyst" ] ], "additional_components": [ "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730", "A6H720", "ENSBTAT00000069542", "Q1LZB2", "ENSBTAT00000024518", "F1MWF1", "ENSBTAT00000001038", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10070594": { "compartment": "compartment_70101", "id": "reaction_10070594", "reactome": "R-BTA-5218642", "name": "PTK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070591" ], "products": [ "species_10070578", "species_29370" ], "modifiers": [ [ "species_10070591", "catalyst" ] ], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10070596": { "compartment": "compartment_876", "id": "reaction_10070596", "reactome": "R-BTA-5218645", "name": "SRC-1 binds p-Y397-PTK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070578", "species_10040957" ], "products": [ "species_10070580" ], "modifiers": [], "additional_components": [ "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1N508", "ENSBTAT00000085237", "E1BLY9", "ENSBTAT00000034285", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10056781": { "compartment": "compartment_876", "id": "reaction_10056781", "reactome": "R-BTA-1236398", "name": "ERBB4 binds NRGs or EGF-like ligands", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056771", "species_10056765" ], "products": [ "species_10056779" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057151": { "compartment": "compartment_984", "id": "reaction_10057151", "reactome": "R-BTA-1250220", "name": "Homodimerization of ERBB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056779" ], "products": [ "species_10057149" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057166": { "compartment": "compartment_70101", "id": "reaction_10057166", "reactome": "R-BTA-1250315", "name": "Trans-autophosphorylation of ERBB4 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10057149" ], "products": [ "species_29370", "species_10057163" ], "modifiers": [ [ "species_10057149", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015" ] }, "reaction_10057184": { "compartment": "compartment_876", "id": "reaction_10057184", "reactome": "R-BTA-1250370", "name": "Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10057181", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "E1BIN8", "ENSBTAT00000029015", "A0A3Q1MKB4", "ENSBTAT00000084727", "P32871", "ENSBTAT00000072391" ] }, "reaction_10090971": { "compartment": "compartment_876", "id": "reaction_10090971", "reactome": "R-BTA-9612219", "name": "ERBB4s80 binds to SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10057211" ], "products": [ "species_10057250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057262": { "compartment": "compartment_70101", "id": "reaction_10057262", "reactome": "R-BTA-1253282", "name": "ERBB4 ubiquitination by WWP1/ITCH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10057257" ], "products": [ "species_10057259" ], "modifiers": [ [ "species_10057257", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057264": { "compartment": "compartment_876", "id": "reaction_10057264", "reactome": "R-BTA-1253300", "name": "ERBB4 binds WWP1/ITCH ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055126", "species_10057255" ], "products": [ "species_10057257" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020867", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "Q32PG0", "ENSBTAT00000020867" ] }, "reaction_10057272": { "compartment": "compartment_70101", "id": "reaction_10057272", "reactome": "R-BTA-1253343", "name": "WWOX binds ERBB4s80", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10057211" ], "products": [ "species_10057270" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10057298": { "compartment": "compartment_70101", "id": "reaction_10057298", "reactome": "R-BTA-1254376", "name": "Translocation of cytosolic ERBB4s80 to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057296" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727" ] }, "reaction_10057236": { "compartment": "compartment_70101", "id": "reaction_10057236", "reactome": "R-BTA-1251997", "name": "Cleavage of ERBB4m80 by gamma-scretase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057201" ], "products": [ "species_10057211" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10057252": { "compartment": "compartment_70101", "id": "reaction_10057252", "reactome": "R-BTA-1252013", "name": "Translocation of ERBB4s80 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057211" ], "products": [ "species_10057246" ], "modifiers": [ [ "species_10057250", "inhibitor" ] ], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10057284": { "compartment": "compartment_70101", "id": "reaction_10057284", "reactome": "R-BTA-1254248", "name": "Translocation of ERBB4s80:YAP1 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057278" ], "products": [ "species_10057282" ], "modifiers": [], "additional_components": [ "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10057286": { "compartment": "compartment_70101", "id": "reaction_10057286", "reactome": "R-BTA-1254251", "name": "ERBB4s80 binds YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057276", "species_10057211" ], "products": [ "species_10057278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "A0A3Q1MKB4", "ENSBTAT00000084727", "A0A3Q1MKB4", "ENSBTAT00000084727", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10084080": { "compartment": "compartment_984", "id": "reaction_10084080", "reactome": "R-BTA-8852552", "name": "MST1R autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084065" ], "products": [ "species_29370", "species_10084077" ], "modifiers": [ [ "species_10084065", "catalyst" ] ], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10084067": { "compartment": "compartment_984", "id": "reaction_10084067", "reactome": "R-BTA-8852522", "name": "MST1 dimer:MST1R dimer binds MST1R dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080868", "species_10080866" ], "products": [ "species_10084065" ], "modifiers": [], "additional_components": [ "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663" ] }, "reaction_10080870": { "compartment": "compartment_876", "id": "reaction_10080870", "reactome": "R-BTA-6800315", "name": "MST1 binds MST1R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080866", "species_10080858" ], "products": [ "species_10080868" ], "modifiers": [], "additional_components": [ "E1BCZ6", "ENSBTAT00000020028", "E1BDW7", "ENSBTAT00000030663", "E1BDW7", "ENSBTAT00000030663", "E1BCZ6", "ENSBTAT00000020028" ] }, "reaction_10091705": { "compartment": "compartment_459", "id": "reaction_10091705", "reactome": "R-BTA-9674531", "name": "AAMP binds EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091695", "species_10040201" ], "products": [ "species_10091703" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005126", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3SZK1", "ENSBTAT00000005126" ] }, "reaction_10040393": { "compartment": "compartment_70101", "id": "reaction_10040393", "reactome": "R-BTA-182993", "name": "Ubiquitination of stimulated EGFR (CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040366" ], "products": [ "species_10040388" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040458": { "compartment": "compartment_70101", "id": "reaction_10040458", "reactome": "R-BTA-183058", "name": "Phosphorylation of CBL (EGFR:GRB2:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040455", "species_113592" ], "products": [ "species_29370", "species_10040395" ], "modifiers": [ [ "species_10040455", "catalyst" ] ], "additional_components": [ "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040460": { "compartment": "compartment_70101", "id": "reaction_10040460", "reactome": "R-BTA-183067", "name": "Localization of CBL:GRB2 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10040449" ], "products": [ "species_10040455" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040447": { "compartment": "compartment_70101", "id": "reaction_10040447", "reactome": "R-BTA-183051", "name": "CBL ubiquitinates Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040440" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040440", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324" ] }, "reaction_10040462": { "compartment": "compartment_70101", "id": "reaction_10040462", "reactome": "R-BTA-183089", "name": "CBL binds and ubiquitinates phosphorylated Sprouty", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040382", "species_10040366" ], "products": [ "species_10040444" ], "modifiers": [ [ "species_10040366", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040369": { "compartment": "compartment_70101", "id": "reaction_10040369", "reactome": "R-BTA-182969", "name": "Phosphorylation of CBL (EGFR:CBL)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040361" ], "products": [ "species_29370", "species_10040366" ], "modifiers": [ [ "species_10040361", "catalyst" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040432": { "compartment": "compartment_70101", "id": "reaction_10040432", "reactome": "R-BTA-183036", "name": "Ubiquitination of stimulated EGFR (CBL:GRB2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10040395" ], "products": [ "species_10040425" ], "modifiers": [ [ "species_10040395", "catalyst" ], [ "species_10040430", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "ENSBTAT00000061187" ] }, "reaction_10040451": { "compartment": "compartment_70101", "id": "reaction_10040451", "reactome": "R-BTA-183052", "name": "CBL binds to GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10035485" ], "products": [ "species_10040449" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040386": { "compartment": "compartment_876", "id": "reaction_10040386", "reactome": "R-BTA-182988", "name": "Sprouty lures CBL away from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040374", "species_10040359" ], "products": [ "species_10040384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002324", "ENSBTAT00000072559", "A6QLQ1", "ENSBTAT00000028307", "Q08E39", "ENSBTAT00000002324", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040453": { "compartment": "compartment_876", "id": "reaction_10040453", "reactome": "R-BTA-183055", "name": "Binding of CBL to EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10040243" ], "products": [ "species_10040361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072559", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040421": { "compartment": "compartment_70101", "id": "reaction_10040421", "reactome": "R-BTA-182994", "name": "Assembly of EGFR complex in clathrin-coated vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040417", "species_10040395" ], "products": [ "species_10040419" ], "modifiers": [], "additional_components": [ "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1LN00", "ENSBTAT00000072559", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q08DX1", "ENSBTAT00000018755", "A0A3Q1M839", "ENSBTAT00000073657", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10040331": { "compartment": "compartment_70101", "id": "reaction_10040331", "reactome": "R-BTA-177945", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040301", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040303": { "compartment": "compartment_70101", "id": "reaction_10040303", "reactome": "R-BTA-177936", "name": "GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10040283" ], "products": [ "species_10040301" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040286": { "compartment": "compartment_70101", "id": "reaction_10040286", "reactome": "R-BTA-177933", "name": "SHC1 phosphorylation by phosphorylated EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040256", "species_113592" ], "products": [ "species_29370", "species_10040283" ], "modifiers": [ [ "species_10040256", "catalyst" ] ], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040258": { "compartment": "compartment_70101", "id": "reaction_10040258", "reactome": "R-BTA-177925", "name": "SHC1 binds to the phosphorylated EGF receptor:ligand complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035544" ], "products": [ "species_10040256" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040289": { "compartment": "compartment_70101", "id": "reaction_10040289", "reactome": "R-BTA-177934", "name": "EGFR autophosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040227", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10036616": { "compartment": "compartment_70101", "id": "reaction_10036616", "reactome": "R-BTA-109813", "name": "GRB2-1 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10035485" ], "products": [ "species_10035491" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10040317": { "compartment": "compartment_70101", "id": "reaction_10040317", "reactome": "R-BTA-177938", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10040314", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040326": { "compartment": "compartment_70101", "id": "reaction_10040326", "reactome": "R-BTA-177943", "name": "GRB2:SOS1 complex binds to EGF:EGFR complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10035491" ], "products": [ "species_10040314" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040323": { "compartment": "compartment_984", "id": "reaction_10040323", "reactome": "R-BTA-177942", "name": "EGFR binds EGF ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040223", "species_10040201" ], "products": [ "species_10040225" ], "modifiers": [ [ "species_10040321", "inhibitor" ] ], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000067365", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "ENSBTAT00000030750" ] }, "reaction_10040229": { "compartment": "compartment_876", "id": "reaction_10040229", "reactome": "R-BTA-177922", "name": "EGFR dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040225" ], "products": [ "species_10040227" ], "modifiers": [], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295" ] }, "reaction_10044472": { "compartment": "compartment_876", "id": "reaction_10044472", "reactome": "R-BTA-212713", "name": "Active PLC-gamma1 dissociates from EGFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044467" ], "products": [ "species_10043237", "species_10040243" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044465": { "compartment": "compartment_876", "id": "reaction_10044465", "reactome": "R-BTA-212706", "name": "Phospholipase C-gamma1 binds to the activated EGF receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040243", "species_10043197" ], "products": [ "species_10044463" ], "modifiers": [], "additional_components": [ "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10044470": { "compartment": "compartment_70101", "id": "reaction_10044470", "reactome": "R-BTA-212710", "name": "EGFR activates PLC-gamma1 by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044463" ], "products": [ "species_29370", "species_10044467" ], "modifiers": [ [ "species_10044463", "catalyst" ] ], "additional_components": [ "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "F1MYF9", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365" ] }, "reaction_10040310": { "compartment": "compartment_70101", "id": "reaction_10040310", "reactome": "R-BTA-177937", "name": "Phosphorylation of EGFR by SRC kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040227", "species_113592" ], "products": [ "species_10040243", "species_29370" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "A0A3Q1MHB0", "ENSBTAT00000067365", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "E1BBE2", "ENSBTAT00000013571", "A0A3Q1M7J4", "ENSBTAT00000085129", "E1BIN8", "ENSBTAT00000029015", "F1MEV4", "ENSBTAT00000024140", "E1BDM2", "ENSBTAT00000005295", "A0A3Q1MHB0", "ENSBTAT00000067365", "ENSBTAT00000011767" ] }, "reaction_10035536": { "compartment": "compartment_70101", "id": "reaction_10035536", "reactome": "R-BTA-74746", "name": "GRB2-1:SOS1 binds p-Y427-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10035532" ], "products": [ "species_10035534" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10075065": { "compartment": "compartment_70101", "id": "reaction_10075065", "reactome": "R-BTA-5686074", "name": "GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036626" ], "products": [ "species_10036624", "species_10035532" ], "modifiers": [], "additional_components": [ "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "ENSBTAT00000075224" ] }, "reaction_10075097": { "compartment": "compartment_70101", "id": "reaction_10075097", "reactome": "R-BTA-5686315", "name": "GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036628" ], "products": [ "species_10036624", "species_10035503" ], "modifiers": [], "additional_components": [ "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471", "F1MYE0", "ENSBTAT00000028392", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10083487": { "compartment": "compartment_70101", "id": "reaction_10083487", "reactome": "R-BTA-8848110", "name": "SOCS3 binds activated PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051731", "species_10083480" ], "products": [ "species_10083485" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011106", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q9BEG9", "ENSBTAT00000011106" ] }, "reaction_10083565": { "compartment": "compartment_70101", "id": "reaction_10083565", "reactome": "R-BTA-8848436", "name": "PTK6 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083556", "species_113592" ], "products": [ "species_29370", "species_10083562", "species_10083480" ], "modifiers": [ [ "species_10083556", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083558": { "compartment": "compartment_70101", "id": "reaction_10083558", "reactome": "R-BTA-8848414", "name": "Activated PTK6 binds CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083554", "species_10083480" ], "products": [ "species_10083556" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10083646": { "compartment": "compartment_70101", "id": "reaction_10083646", "reactome": "R-BTA-8848864", "name": "PTK6 binds ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083642", "species_10083480" ], "products": [ "species_10083644" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083632": { "compartment": "compartment_70101", "id": "reaction_10083632", "reactome": "R-BTA-8848818", "name": "PTK6 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_113592" ], "products": [ "species_29370", "species_10052267" ], "modifiers": [ [ "species_10083480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000061122" ] }, "reaction_10083652": { "compartment": "compartment_70101", "id": "reaction_10083652", "reactome": "R-BTA-8848873", "name": "PTK6 phosphorylates ARAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083644" ], "products": [ "species_29370", "species_10083649", "species_10083480" ], "modifiers": [ [ "species_10083644", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568", "ENSBTAT00000079568", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1M4A0", "ENSBTAT00000079568" ] }, "reaction_10083638": { "compartment": "compartment_70101", "id": "reaction_10083638", "reactome": "R-BTA-8848829", "name": "CBL autoubiquitinates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10052267" ], "products": [ "species_10083635" ], "modifiers": [ [ "species_10052267", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000072559", "ENSBTAT00000072559", "ENSBTAT00000072559" ] }, "reaction_10083690": { "compartment": "compartment_70101", "id": "reaction_10083690", "reactome": "R-BTA-8849068", "name": "PTK6 phosphorylates ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083682", "species_113592" ], "products": [ "species_10083687", "species_29370", "species_10083480" ], "modifiers": [ [ "species_10083682", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083581": { "compartment": "compartment_70101", "id": "reaction_10083581", "reactome": "R-BTA-8848596", "name": "PTK6 binds PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070667", "species_10083480" ], "products": [ "species_10083579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083629": { "compartment": "compartment_70101", "id": "reaction_10083629", "reactome": "R-BTA-8848726", "name": "PTK6 phosphorylates BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083620", "species_113592" ], "products": [ "species_29370", "species_10083626", "species_10083480" ], "modifiers": [ [ "species_10083620", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322", "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083695": { "compartment": "compartment_70101", "id": "reaction_10083695", "reactome": "R-BTA-8849082", "name": "ARHGAP35 stimulates RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083692" ], "products": [ "species_10083687", "species_29372", "species_10037313" ], "modifiers": [ [ "species_10083692", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833", "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083697": { "compartment": "compartment_70101", "id": "reaction_10083697", "reactome": "R-BTA-8849085", "name": "ARHGAP35 binds RHOA:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083687", "species_10037315" ], "products": [ "species_10083692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "P61585", "ENSBTAT00000005600", "species_29438", "P61585", "ENSBTAT00000005600", "species_29438", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083588": { "compartment": "compartment_70101", "id": "reaction_10083588", "reactome": "R-BTA-8848606", "name": "PTK6 phosphorylates PXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083579" ], "products": [ "species_29370", "species_10083585", "species_10083480" ], "modifiers": [ [ "species_10083579", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101", "ENSBTAT00000024101", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "F1MFD1", "ENSBTAT00000024101" ] }, "reaction_10083684": { "compartment": "compartment_70101", "id": "reaction_10083684", "reactome": "R-BTA-8849055", "name": "PTK6 binds ARHGAP35", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083680", "species_10083480" ], "products": [ "species_10083682" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085833", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "E1B801", "ENSBTAT00000085833" ] }, "reaction_10083622": { "compartment": "compartment_70101", "id": "reaction_10083622", "reactome": "R-BTA-8848713", "name": "PTK6 binds BCAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083618", "species_10083480" ], "products": [ "species_10083620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073322", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A0A3Q1MQ07", "ENSBTAT00000073322" ] }, "reaction_10083707": { "compartment": "compartment_70101", "id": "reaction_10083707", "reactome": "R-BTA-8849102", "name": "SRMS phosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10083480" ], "products": [ "species_10083700", "species_29370" ], "modifiers": [ [ "species_10083704", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061122", "ENSBTAT00000061122", "ENSBTAT00000002574" ] }, "reaction_10083726": { "compartment": "compartment_70101", "id": "reaction_10083726", "reactome": "R-BTA-8849428", "name": "PTPN1 binds PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055952", "species_10083480" ], "products": [ "species_10083724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10083729": { "compartment": "compartment_70101", "id": "reaction_10083729", "reactome": "R-BTA-8849435", "name": "PTPN1 dephosphorylates PTK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10083724" ], "products": [ "species_29372", "species_10055952", "species_10083473" ], "modifiers": [ [ "species_10083724", "catalyst" ] ], "additional_components": [ "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678", "ENSBTAT00000008678", "ENSBTAT00000061122", "E1BNA8", "ENSBTAT00000061122", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090428": { "compartment": "compartment_876", "id": "reaction_10090428", "reactome": "R-BTA-9021627", "name": "EPOR-associated PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10090425", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10089841": { "compartment": "compartment_876", "id": "reaction_10089841", "reactome": "R-BTA-9012657", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047493", "species_10089837" ], "products": [ "species_10089839" ], "modifiers": [], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10090501": { "compartment": "compartment_876", "id": "reaction_10090501", "reactome": "R-BTA-9027272", "name": "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10090415" ], "products": [ "species_29370", "species_10089837" ], "modifiers": [ [ "species_10090415", "catalyst" ] ], "additional_components": [ "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171", "F1MEQ7", "ENSBTAT00000010781", "E1BCP6", "ENSBTAT00000015986", "F1MJE0", "ENSBTAT00000015938", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10073851": { "compartment": "compartment_17938", "id": "reaction_10073851", "reactome": "R-BTA-5672828", "name": "mTORC1 phosphorylates AKT1S1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039143", "species_113592" ], "products": [ "species_29370", "species_10073848" ], "modifiers": [ [ "species_10039143", "catalyst" ] ], "additional_components": [ "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046572": { "compartment": "compartment_70101", "id": "reaction_10046572", "reactome": "R-BTA-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042890", "species_76577" ], "products": [ "species_10046570" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10046588": { "compartment": "compartment_70101", "id": "reaction_10046588", "reactome": "R-BTA-380979", "name": "RHEB in mTORC1:RHEB:GTP hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125" ], "products": [ "species_29372", "species_10046585" ], "modifiers": [ [ "species_10039125", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10046583": { "compartment": "compartment_70101", "id": "reaction_10046583", "reactome": "R-BTA-380949", "name": "AMPK is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10042890" ], "products": [ "species_29372", "species_10042880" ], "modifiers": [ [ "species_10046580", "catalyst" ] ], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MBG5", "ENSBTAT00000000017", "F1MQV7", "ENSBTAT00000024965", "ENSBTAT00000024128" ] }, "reaction_10049894": { "compartment": "compartment_876", "id": "reaction_10049894", "reactome": "R-BTA-447074", "name": "AMPK phosphorylates Raptor in the mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_113592" ], "products": [ "species_29370", "species_10039178" ], "modifiers": [ [ "species_10046570", "catalyst" ] ], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10088493": { "compartment": "compartment_70101", "id": "reaction_10088493", "reactome": "R-BTA-8952716", "name": "SLC38A9 binds Ragulator:Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039075", "species_10039119" ], "products": [ "species_10039121" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084666", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10073853": { "compartment": "compartment_17938", "id": "reaction_10073853", "reactome": "R-BTA-5672843", "name": "AKT1S1 (PRAS40) binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039125", "species_10039145" ], "products": [ "species_10039147" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000007575", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10088496": { "compartment": "compartment_70101", "id": "reaction_10088496", "reactome": "R-BTA-8952726", "name": "SLC38A9 transports L-Arg from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428011" ], "products": [ "species_29468" ], "modifiers": [ [ "species_10039121", "catalyst" ] ], "additional_components": [ "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039059": { "compartment": "compartment_17938", "id": "reaction_10039059", "reactome": "R-BTA-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10039055" ], "products": [ "species_29420", "species_10039057" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29420", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438" ] }, "reaction_10039209": { "compartment": "compartment_70101", "id": "reaction_10039209", "reactome": "R-BTA-165758", "name": "Phosphorylation and inactivation of eEF2K by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039204", "species_113592" ], "products": [ "species_10039207", "species_29370" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023487", "ENSBTAT00000023487", "ENSBTAT00000022415" ] }, "reaction_10039160": { "compartment": "compartment_70101", "id": "reaction_10039160", "reactome": "R-BTA-165708", "name": "Dissociation of phosphorylated 4EBP1 from eIF4E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039133" ], "products": [ "species_10034357", "species_10039131" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10091741": { "compartment": "compartment_70101", "id": "reaction_10091741", "reactome": "R-BTA-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678687", "species_10039151" ], "products": [ "species_10039153" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10039180": { "compartment": "compartment_17938", "id": "reaction_10039180", "reactome": "R-BTA-165718", "name": "mTORC1 phosphorylation of RPS6KB1 (S6K)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10039164" ], "products": [ "species_29370", "species_10039168" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039178", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022415", "ENSBTAT00000022415", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10039200": { "compartment": "compartment_70101", "id": "reaction_10039200", "reactome": "R-BTA-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034529" ], "products": [ "species_29370", "species_10039197" ], "modifiers": [ [ "species_10039168", "catalyst" ] ], "additional_components": [ "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1N412", "ENSBTAT00000019214", "ENSBTAT00000022415" ] }, "reaction_10039155": { "compartment": "compartment_17938", "id": "reaction_10039155", "reactome": "R-BTA-165692", "name": "Phosphorylation of 4E-BP1 by activated mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10034363" ], "products": [ "species_29370", "species_10039133" ], "modifiers": [ [ "species_10039125", "catalyst" ], [ "species_10039143", "catalyst" ], [ "species_10039153", "inhibitor" ], [ "species_10039147", "inhibitor" ] ], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "P18203", "ENSBTAT00000010928", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072900": { "compartment": "compartment_70101", "id": "reaction_10072900", "reactome": "R-BTA-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039101", "species_10039115" ], "products": [ "species_10039117" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438" ] }, "reaction_10073844": { "compartment": "compartment_17938", "id": "reaction_10073844", "reactome": "R-BTA-5672824", "name": "Phosphorylated AKT1S1:mTORC1 binds YWHAB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039141", "species_10037666" ], "products": [ "species_10039143" ], "modifiers": [], "additional_components": [ "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "ENSBTAT00000022411", "A0A140T894", "ENSBTAT00000022411", "F1N197", "ENSBTAT00000007575", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10039127": { "compartment": "compartment_70101", "id": "reaction_10039127", "reactome": "R-BTA-165680", "name": "Formation of active mTORC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039123", "species_10039057" ], "products": [ "species_10039125" ], "modifiers": [], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666" ] }, "reaction_10072902": { "compartment": "compartment_70101", "id": "reaction_10072902", "reactome": "R-BTA-5653974", "name": "Ragulator binds Rag dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039095", "species_10039117" ], "products": [ "species_10039119" ], "modifiers": [], "additional_components": [ "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10046602": { "compartment": "compartment_12045", "id": "reaction_10046602", "reactome": "R-BTA-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046594", "species_113592" ], "products": [ "species_10046599", "species_29370" ], "modifiers": [ [ "species_10046594", "catalyst" ] ], "additional_components": [ "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10046604": { "compartment": "compartment_12045", "id": "reaction_10046604", "reactome": "R-BTA-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046592" ], "products": [ "species_10046594" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022347", "F1MM00", "ENSBTAT00000022347" ] }, "reaction_10085865": { "compartment": "compartment_7660", "id": "reaction_10085865", "reactome": "R-BTA-8874849", "name": "CREBRF binds CREB3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085861", "species_10085857" ], "products": [ "species_10085863" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065187", "ENSBTAT00000015193", "Q8SQ19", "ENSBTAT00000015193", "E1BPS0", "ENSBTAT00000065187" ] }, "reaction_10060285": { "compartment": "compartment_161320", "id": "reaction_10060285", "reactome": "R-BTA-1630304", "name": "GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2105007", "species_1605715" ], "products": [ "species_2104997", "species_1606845" ], "modifiers": [ [ "species_10060282", "catalyst" ] ], "additional_components": [ "F1MU84", "ENSBTAT00000006001" ] }, "reaction_10091293": { "compartment": "compartment_161320", "id": "reaction_10091293", "reactome": "R-BTA-9638078", "name": "HEXB cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060293": { "compartment": "compartment_161320", "id": "reaction_10060293", "reactome": "R-BTA-1638032", "name": "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2104995" ], "products": [ "species_1606845", "species_2105012" ], "modifiers": [ [ "species_10060290", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023218" ] }, "reaction_10060295": { "compartment": "compartment_161320", "id": "reaction_10060295", "reactome": "R-BTA-1638053", "name": "HEXA cleaves the terminal GalNAc from keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105012" ], "products": [ "species_2105010", "species_1605658" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10063510": { "compartment": "compartment_984", "id": "reaction_10063510", "reactome": "R-BTA-2046239", "name": "Extracellular KSPG translocates to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063483" ], "products": [ "species_10060854" ], "modifiers": [], "additional_components": [ "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279" ] }, "reaction_10038201": { "compartment": "compartment_984", "id": "reaction_10038201", "reactome": "R-BTA-158311", "name": "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038157" ], "products": [ "species_10038198", "species_10038196", "species_10038188" ], "modifiers": [ [ "species_10038157", "catalyst" ] ], "additional_components": [ "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10091546": { "compartment": "compartment_17957", "id": "reaction_10091546", "reactome": "R-BTA-9650473", "name": "SERPING1 is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091544" ], "products": [ "species_10038209" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "ENSBTAT00000021638" ] }, "reaction_10038205": { "compartment": "compartment_984", "id": "reaction_10038205", "reactome": "R-BTA-158354", "name": "kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038143", "species_10038203" ], "products": [ "species_10038145" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "Q3T0B6", "ENSBTAT00000013734", "ENSBTAT00000053071", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734" ] }, "reaction_10090718": { "compartment": "compartment_984", "id": "reaction_10090718", "reactome": "R-BTA-9603302", "name": "Factor IIa inhibitors (peptide) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603327", "species_10037577" ], "products": [ "species_10038217" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038129": { "compartment": "compartment_984", "id": "reaction_10038129", "reactome": "R-BTA-158145", "name": "factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037535", "species_10038121" ], "products": [ "species_10038127" ], "modifiers": [], "additional_components": [ "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945" ] }, "reaction_10091600": { "compartment": "compartment_17957", "id": "reaction_10091600", "reactome": "R-BTA-9661625", "name": "FVIII is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076686" ], "products": [ "species_10038115" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10091671": { "compartment": "compartment_984", "id": "reaction_10091671", "reactome": "R-BTA-9670014", "name": "Factor VIIIa dissociates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10091669", "species_10071930" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726", "ENSBTAT00000036726" ] }, "reaction_10038166": { "compartment": "compartment_876", "id": "reaction_10038166", "reactome": "R-BTA-158251", "name": "prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038147" ], "products": [ "species_10038157" ], "modifiers": [ [ "species_10038163", "catalyst" ] ], "additional_components": [ "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "F1MAU4", "ENSBTAT00000047906" ] }, "reaction_10090185": { "compartment": "compartment_984", "id": "reaction_10090185", "reactome": "R-BTA-9015379", "name": "Factor IIa inhibitors (compounds) binds IIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9603311", "species_10037577" ], "products": [ "species_10038215" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10071946": { "compartment": "compartment_984", "id": "reaction_10071946", "reactome": "R-BTA-5607043", "name": "factor VIIIa associates with cell membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071934" ], "products": [ "species_10038174" ], "modifiers": [], "additional_components": [ "G5E5W1", "ENSBTAT00000036726", "G5E5W1", "ENSBTAT00000036726" ] }, "reaction_10038221": { "compartment": "compartment_984", "id": "reaction_10038221", "reactome": "R-BTA-158419", "name": "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038127" ], "products": [ "species_10038182" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ], [ "species_10038219", "inhibitor" ] ], "additional_components": [ "A0A3Q1LT55", "ENSBTAT00000087456", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "F1N1G4", "ENSBTAT00000019525", "E1BG29", "ENSBTAT00000017571", "E1B863", "ENSBTAT00000055945", "A0A3Q1LT55", "ENSBTAT00000087456", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10038149": { "compartment": "compartment_876", "id": "reaction_10038149", "reactome": "R-BTA-158218", "name": "prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038133", "species_10038145" ], "products": [ "species_10038147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012503", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "A0A140T8C8", "ENSBTAT00000053071", "Q3T0B6", "ENSBTAT00000013734", "Q2KJ63", "ENSBTAT00000012503" ] }, "reaction_10038213": { "compartment": "compartment_984", "id": "reaction_10038213", "reactome": "R-BTA-158399", "name": "kallikrein binds SERPING1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038209", "species_10038188" ], "products": [ "species_10038211" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021638", "Q2KJ63", "ENSBTAT00000012503", "Q2KJ63", "ENSBTAT00000012503", "E1BMJ0", "ENSBTAT00000021638" ] }, "reaction_10035301": { "compartment": "compartment_7660", "id": "reaction_10035301", "reactome": "R-BTA-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035297", "species_10035293" ], "products": [ "species_10035299" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006308", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "E1B883", "ENSBTAT00000006308" ] }, "reaction_10035254": { "compartment": "compartment_350", "id": "reaction_10035254", "reactome": "R-BTA-73718", "name": "UBF-1 Binds rDNA Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73682", "species_10035051" ], "products": [ "species_10035053" ], "modifiers": [ [ "species_10035231", "inhibitor" ], [ "species_10035252", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000034806", "F1MCZ7", "ENSBTAT00000034806", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10034224": { "compartment": "compartment_70101", "id": "reaction_10034224", "reactome": "R-BTA-71732", "name": "pyrophosphate + H2O => 2 orthophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10034221", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P37980", "ENSBTAT00000010311" ] }, "reaction_10050169": { "compartment": "compartment_5460", "id": "reaction_10050169", "reactome": "R-BTA-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159450", "species_113521" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10050166", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "A0A3Q1LXA8", "ENSBTAT00000086411" ] }, "reaction_10038107": { "compartment": "compartment_70101", "id": "reaction_10038107", "reactome": "R-BTA-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10038103" ], "products": [ "species_10038105" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005581", "Q3SYU2", "ENSBTAT00000005581", "species_29438" ] }, "reaction_10038082": { "compartment": "compartment_70101", "id": "reaction_10038082", "reactome": "R-BTA-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034837" ], "products": [ "species_10038080", "species_10034641" ], "modifiers": [], "additional_components": [ "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000035330" ] }, "reaction_10034365": { "compartment": "compartment_70101", "id": "reaction_10034365", "reactome": "R-BTA-72622", "name": "Release of eIF4E from the inactive eIF4E:4E-BP complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034363" ], "products": [ "species_10034357", "species_10034361" ], "modifiers": [], "additional_components": [ "Q0P5A7", "ENSBTAT00000039828", "A0A3Q1NEI6", "ENSBTAT00000068997", "ENSBTAT00000068997", "ENSBTAT00000039828" ] }, "reaction_10034855": { "compartment": "compartment_70101", "id": "reaction_10034855", "reactome": "R-BTA-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034839", "species_10034853" ], "products": [ "species_10034853", "species_10034837", "species_10034609" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "ENSBTAT00000023455", "ENSBTAT00000023455", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484" ] }, "reaction_10034905": { "compartment": "compartment_70101", "id": "reaction_10034905", "reactome": "R-BTA-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034901", "species_10034385" ], "products": [ "species_10034903" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "E1B7R4", "ENSBTAT00000061515", "E1BLZ8", "ENSBTAT00000049219", "A7MB16", "ENSBTAT00000084055", "Q3T0V3", "ENSBTAT00000014888", "Q5E966", "ENSBTAT00000077067", "Q3ZCK1", "ENSBTAT00000014281", "Q3T122", "ENSBTAT00000037985", "Q3SYW6", "ENSBTAT00000023384", "Q32LC3", "ENSBTAT00000023455" ] }, "reaction_10034383": { "compartment": "compartment_70101", "id": "reaction_10034383", "reactome": "R-BTA-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10034379" ], "products": [ "species_10034381" ], "modifiers": [], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10034387": { "compartment": "compartment_70101", "id": "reaction_10034387", "reactome": "R-BTA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_72393", "species_10034381" ], "products": [ "species_10034385" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "species_29438" ] }, "reaction_10060894": { "compartment": "compartment_70101", "id": "reaction_10060894", "reactome": "R-BTA-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060890", "species_10060888" ], "products": [ "species_10060892" ], "modifiers": [], "additional_components": [ "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q2T9U1", "ENSBTAT00000025405", "E1BB38", "ENSBTAT00000014015", "A6QQL9", "ENSBTAT00000019085", "A0A3Q1LYQ7", "ENSBTAT00000076619", "Q3ZBG7", "ENSBTAT00000017007", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912" ] }, "reaction_10048380": { "compartment": "compartment_17957", "id": "reaction_10048380", "reactome": "R-BTA-421416", "name": "Proglucagon translocates from the ER Lumen to secretory granules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048376" ], "products": [ "species_10048378" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972" ] }, "reaction_10046723": { "compartment": "compartment_984", "id": "reaction_10046723", "reactome": "R-BTA-383313", "name": "Glucagon-like Peptide 1 is secreted from intestinal L cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046709" ], "products": [ "species_10046626" ], "modifiers": [ [ "species_10046721", "catalyst" ], [ "species_10046044", "catalyst" ], [ "species_10046717", "catalyst" ], [ "species_10046130", "catalyst" ], [ "species_70115", "catalyst" ], [ "species_372533", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000972", "ENSBTAT00000000972", "E1B8Q3", "ENSBTAT00000026313", "A0A3Q1NGS8", "ENSBTAT00000082648", "G1K1V2", "ENSBTAT00000023234", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "G5E5H9", "ENSBTAT00000019647", "species_8848483", "CHEBI:71466", "CHEBI:28716", "species_426576", "CHEBI:28875", "CHEBI:53460", "CHEBI:27997", "CHEBI:16196", "species_9024011", "CHEBI:53487", "CHEBI:53486", "species_8934421", "species_9608444", "CHEBI:28661", "species_2026977", "species_2046056", "E1BKC0", "ENSBTAT00000000560" ] }, "reaction_10045736": { "compartment": "compartment_984", "id": "reaction_10045736", "reactome": "R-BTA-378975", "name": "Follitropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045700", "species_10041260" ], "products": [ "species_10045702" ], "modifiers": [ [ "species_10045734", "catalyst" ], [ "species_10045722", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000014462", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04837", "ENSBTAT00000014462", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07995", "ENSBTAT00000066382", "E1B7M7", "ENSBTAT00000025401", "E1BFT5", "ENSBTAT00000008663", "P07994", "ENSBTAT00000013154" ] }, "reaction_10045694": { "compartment": "compartment_984", "id": "reaction_10045694", "reactome": "R-BTA-378952", "name": "Thyrotropin is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043952", "species_10041260" ], "products": [ "species_10043954" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008264", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10045744": { "compartment": "compartment_984", "id": "reaction_10045744", "reactome": "R-BTA-378978", "name": "CGA and CGB3 bind to form Human chorionic gonadotropin (hCG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041260", "species_10045740" ], "products": [ "species_10045742" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078886", "ENSBTAT00000057054", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10045696": { "compartment": "compartment_984", "id": "reaction_10045696", "reactome": "R-BTA-378956", "name": "Luteinizing hormone is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041265", "species_10041260" ], "products": [ "species_10041267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000057054", "ENSBTAT00000078886", "P01217", "ENSBTAT00000078886", "P04651", "ENSBTAT00000057054" ] }, "reaction_10091056": { "compartment": "compartment_984", "id": "reaction_10091056", "reactome": "R-BTA-9619024", "name": "CES1trimer hydrolyses ACEI pro-drugs to ACEIs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_9619052" ], "products": [ "species_8878776", "species_9619021" ], "modifiers": [ [ "species_10076366", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461" ] }, "reaction_10048461": { "compartment": "compartment_17957", "id": "reaction_10048461", "reactome": "R-BTA-422051", "name": "Cleavage of the signal peptide of Preproghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048434" ], "products": [ "species_10048438" ], "modifiers": [ [ "species_10048458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "P67810", "ENSBTAT00000014925", "Q2KI36", "ENSBTAT00000015866", "A0A3Q1MLX7", "ENSBTAT00000083476", "E1BEI2", "ENSBTAT00000008726" ] }, "reaction_10048429": { "compartment": "compartment_876", "id": "reaction_10048429", "reactome": "R-BTA-422048", "name": "Acyl Ghrelin and C-Ghrelin are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048421", "species_10048413" ], "products": [ "species_10048423", "species_10046085" ], "modifiers": [ [ "species_10046613", "catalyst" ], [ "species_70115", "inhibitor" ], [ "species_10038908", "inhibitor" ], [ "species_10048427", "inhibitor" ], [ "species_422024", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000014713", "ENSBTAT00000000972", "ENSBTAT00000082606" ] }, "reaction_10048465": { "compartment": "compartment_17957", "id": "reaction_10048465", "reactome": "R-BTA-422104", "name": "Ghrelin O-acyltransferase octanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_422042", "species_10048398" ], "products": [ "species_10048463" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10048407": { "compartment": "compartment_17957", "id": "reaction_10048407", "reactome": "R-BTA-422017", "name": "Ghrelin O-acyltransferase decanoylates Proghrelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048398", "species_422019" ], "products": [ "species_10048400" ], "modifiers": [ [ "species_10048404", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016350", "ENSBTAT00000016350", "ENSBTAT00000000986" ] }, "reaction_10049385": { "compartment": "compartment_1462052", "id": "reaction_10049385", "reactome": "R-BTA-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049382", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001343" ] }, "reaction_10049392": { "compartment": "compartment_20699", "id": "reaction_10049392", "reactome": "R-BTA-437136", "name": "SLC30A8 transports Zn2+ from cytosol to secretory granule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10049389", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086579" ] }, "reaction_10085101": { "compartment": "compartment_70101", "id": "reaction_10085101", "reactome": "R-BTA-8865774", "name": "TTLLs polyglutamylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29404", "species_113592" ], "products": [ "species_10085076", "species_29372", "species_29370" ], "modifiers": [ [ "species_10085098", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "G3N2U5", "ENSBTAT00000064999", "A7E2Z5", "ENSBTAT00000017043", "E1BKB4", "ENSBTAT00000069658" ] }, "reaction_10085250": { "compartment": "compartment_70101", "id": "reaction_10085250", "reactome": "R-BTA-8867370", "name": "TTLL3, TTLL8, TTLL10 polyglycylate tubulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_113592", "species_29424" ], "products": [ "species_29372", "species_10085237", "species_29370" ], "modifiers": [ [ "species_10085247", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N325", "ENSBTAT00000034047", "G3N3S4", "ENSBTAT00000065735" ] }, "reaction_10087993": { "compartment": "compartment_70101", "id": "reaction_10087993", "reactome": "R-BTA-8952044", "name": "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087978" ], "products": [ "species_10087990", "species_10087869" ], "modifiers": [ [ "species_10087978", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MXH0", "ENSBTAT00000068692", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207" ] }, "reaction_10087848": { "compartment": "compartment_70101", "id": "reaction_10087848", "reactome": "R-BTA-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10075935", "species_10087835" ], "products": [ "species_111294", "species_10087845", "species_76577" ], "modifiers": [ [ "species_10087835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10087883": { "compartment": "compartment_70101", "id": "reaction_10087883", "reactome": "R-BTA-8951764", "name": "Transfer of NEDD8 to AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087871" ], "products": [ "species_10087845", "species_10087880" ], "modifiers": [ [ "species_10087871", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "Q1RMW1", "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087885": { "compartment": "compartment_70101", "id": "reaction_10087885", "reactome": "R-BTA-8951766", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2F", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087869", "species_10087850" ], "products": [ "species_10087871" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037020", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367", "Q1RMW1", "ENSBTAT00000037020" ] }, "reaction_10087852": { "compartment": "compartment_70101", "id": "reaction_10087852", "reactome": "R-BTA-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087845", "species_113592", "species_10075935" ], "products": [ "species_111294", "species_10087850", "species_76577" ], "modifiers": [], "additional_components": [ "A0A3Q1MJI4", "ENSBTAT00000077128", "E1BJ64", "ENSBTAT00000028591", "E1B8X4", "ENSBTAT00000013367", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MJI4", "ENSBTAT00000077128", "E1B8X4", "ENSBTAT00000013367" ] }, "reaction_10088734": { "compartment": "compartment_7660", "id": "reaction_10088734", "reactome": "R-BTA-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088730", "species_10088728" ], "products": [ "species_10088732" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q32L87", "ENSBTAT00000004550", "F1MYV7", "ENSBTAT00000019879", "F1MVI8", "ENSBTAT00000028594", "A0A3Q1LPL4", "ENSBTAT00000070605", "G3MXE6", "ENSBTAT00000015886", "E1BMD0", "ENSBTAT00000010105", "A0A3Q1MY43", "ENSBTAT00000086238", "A4FUE3", "ENSBTAT00000021204", "A0A3Q1LT78", "ENSBTAT00000084712", "Q5E9A9", "ENSBTAT00000022696", "F1N3H0", "ENSBTAT00000086437", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10087825": { "compartment": "compartment_70101", "id": "reaction_10087825", "reactome": "R-BTA-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075937" ], "products": [ "species_10075927", "species_10075935" ], "modifiers": [], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000079440", "ENSBTAT00000028591" ] }, "reaction_10088688": { "compartment": "compartment_70101", "id": "reaction_10088688", "reactome": "R-BTA-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10088684" ], "products": [ "species_10088686" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A6QPV4", "ENSBTAT00000006480", "Q29RM5", "ENSBTAT00000004519", "E1BL53", "ENSBTAT00000030804", "F1N162", "ENSBTAT00000011028", "A7MB89", "ENSBTAT00000011464", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10088787": { "compartment": "compartment_70101", "id": "reaction_10088787", "reactome": "R-BTA-8956026", "name": "CUL9:RBX1 ubiquitinates BIRC5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10088761" ], "products": [ "species_10088764" ], "modifiers": [ [ "species_10088774", "catalyst" ], [ "species_10088785", "inhibitor" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000018046", "ENSBTAT00000018046", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591", "F6R7X9", "ENSBTAT00000024194", "E1BK00", "ENSBTAT00000061262", "A0A3Q1LNF8", "ENSBTAT00000075328", "E1BM39", "ENSBTAT00000026522", "E1BJ64", "ENSBTAT00000028591" ] }, "reaction_10088807": { "compartment": "compartment_70101", "id": "reaction_10088807", "reactome": "R-BTA-8956040", "name": "COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088802" ], "products": [ "species_10088804", "species_10075935" ], "modifiers": [ [ "species_10084815", "catalyst" ] ], "additional_components": [ "A0A3Q1MTL8", "ENSBTAT00000087337", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "A0A3Q1MXH0", "ENSBTAT00000068692", "A0A3Q1MTL8", "ENSBTAT00000087337", "Q2KII4", "ENSBTAT00000078734", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "E1BHZ2", "ENSBTAT00000024202", "Q3MHZ2", "ENSBTAT00000022024", "A0A3Q1MJT8", "ENSBTAT00000070334", "F1MWW0", "ENSBTAT00000011810", "A0A3Q1M5W3", "ENSBTAT00000075739", "Q9BEG9", "ENSBTAT00000011106", "E1BJ12", "ENSBTAT00000025032", "F1MTH7", "ENSBTAT00000001270", "F1N349", "ENSBTAT00000002623", "E1BKN8", "ENSBTAT00000023144", "A7MBH6", "ENSBTAT00000044628", "A0A452DJ71", "ENSBTAT00000038842", "H7BWV6", "ENSBTAT00000009484", "Q2HJ53", "ENSBTAT00000030652", "G3N2Y1", "ENSBTAT00000064452", "E1BCM1", "ENSBTAT00000069213", "E1B9S2", "ENSBTAT00000013884", "E1BEH6", "ENSBTAT00000004378", "E1BKE5", "ENSBTAT00000064207", "ENSBTAT00000028591", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10075942": { "compartment": "compartment_70101", "id": "reaction_10075942", "reactome": "R-BTA-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075933" ], "products": [ "species_10075939", "species_10075937" ], "modifiers": [ [ "species_10075933", "catalyst" ] ], "additional_components": [ "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "ENSBTAT00000028591", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440", "E1BJ64", "ENSBTAT00000028591", "A0A3Q1MIW5", "ENSBTAT00000079440" ] }, "reaction_10038457": { "compartment": "compartment_70101", "id": "reaction_10038457", "reactome": "R-BTA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_8855661", "species_29416" ], "modifiers": [ [ "species_10038454", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017653" ] }, "reaction_10038464": { "compartment": "compartment_12045", "id": "reaction_10038464", "reactome": "R-BTA-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_8855663" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10038461", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012921" ] }, "reaction_10052665": { "compartment": "compartment_17963", "id": "reaction_10052665", "reactome": "R-BTA-914012", "name": "GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052629" ], "products": [ "species_10052652", "species_205687" ], "modifiers": [ [ "species_10052662", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "Q7YQE1", "ENSBTAT00000079217", "A0A3Q1MUB2", "ENSBTAT00000076540" ] }, "reaction_10052521": { "compartment": "compartment_17963", "id": "reaction_10052521", "reactome": "R-BTA-914006", "name": "Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052519", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382" ] }, "reaction_10077688": { "compartment": "compartment_20699", "id": "reaction_10077688", "reactome": "R-BTA-6786012", "name": "CHST4 transfers SO4(2-) from PAPS to Core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10052652" ], "products": [ "species_742343", "species_10077681" ], "modifiers": [ [ "species_10077685", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "ENSBTAT00000022569" ] }, "reaction_10052461": { "compartment": "compartment_20699", "id": "reaction_10052461", "reactome": "R-BTA-913675", "name": "GALNTs transfer GalNAc from UDP-GalNAc to mucins to form Tn antigens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052377" ], "products": [ "species_10052400", "species_205687" ], "modifiers": [ [ "species_10052458", "catalyst" ] ], "additional_components": [ "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1MQ00", "ENSBTAT00000071740", "A0A3Q1M986", "ENSBTAT00000078875", "E1BPR6", "ENSBTAT00000061536", "E1BDW8", "ENSBTAT00000028329", "E1BBP1", "ENSBTAT00000018541", "E1BHN6", "ENSBTAT00000010847", "A6QLX6", "ENSBTAT00000077005", "E1BKQ9", "ENSBTAT00000023104", "Q07537", "ENSBTAT00000081582", "A0A3Q1LM69", "ENSBTAT00000087139", "F6QA59", "ENSBTAT00000023106" ] }, "reaction_10052716": { "compartment": "compartment_20699", "id": "reaction_10052716", "reactome": "R-BTA-914018", "name": "Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052569" ], "products": [ "species_205687", "species_10052713" ], "modifiers": [ [ "species_10052656", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000079217" ] }, "reaction_10052606": { "compartment": "compartment_20699", "id": "reaction_10052606", "reactome": "R-BTA-914010", "name": "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_205687", "species_10052569" ], "modifiers": [ [ "species_10052603", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1MPZ8", "ENSBTAT00000078680", "A7YY64", "ENSBTAT00000024024", "F1MGN7", "ENSBTAT00000063600", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494", "Q0VC83", "ENSBTAT00000021344" ] }, "reaction_10054575": { "compartment": "compartment_20699", "id": "reaction_10054575", "reactome": "R-BTA-977228", "name": "Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000083430" ] }, "reaction_10054766": { "compartment": "compartment_20699", "id": "reaction_10054766", "reactome": "R-BTA-981809", "name": "ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10054701" ], "products": [ "species_10054759", "species_727810" ], "modifiers": [ [ "species_10054763", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "ENSBTAT00000063122" ] }, "reaction_10054722": { "compartment": "compartment_20699", "id": "reaction_10054722", "reactome": "R-BTA-981497", "name": "ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054701" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10054773": { "compartment": "compartment_17963", "id": "reaction_10054773", "reactome": "R-BTA-981814", "name": "GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052629" ], "products": [ "species_727810", "species_10054573" ], "modifiers": [ [ "species_10054770", "catalyst" ] ], "additional_components": [ "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000078008" ] }, "reaction_10054550": { "compartment": "compartment_17963", "id": "reaction_10054550", "reactome": "R-BTA-977071", "name": "Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10052400" ], "products": [ "species_10054548", "species_727810" ], "modifiers": [ [ "species_10054415", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "ENSBTAT00000083430" ] }, "reaction_10052496": { "compartment": "compartment_17963", "id": "reaction_10052496", "reactome": "R-BTA-914005", "name": "Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052494", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675" ] }, "reaction_10061538": { "compartment": "compartment_20699", "id": "reaction_10061538", "reactome": "R-BTA-1964505", "name": "C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10052400" ], "products": [ "species_10052629", "species_205687" ], "modifiers": [ [ "species_10061535", "catalyst" ] ], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "Q0VC84", "ENSBTAT00000068688", "Q3SX46", "ENSBTAT00000028542" ] }, "reaction_10052546": { "compartment": "compartment_17963", "id": "reaction_10052546", "reactome": "R-BTA-914008", "name": "Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052400" ], "products": [ "species_10052544", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10052690": { "compartment": "compartment_17963", "id": "reaction_10052690", "reactome": "R-BTA-914017", "name": "Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10052400" ], "products": [ "species_10052688", "species_205687" ], "modifiers": [], "additional_components": [ "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287" ] }, "reaction_10076773": { "compartment": "compartment_20699", "id": "reaction_10076773", "reactome": "R-BTA-5694487", "name": "A4GNT transfers GlcNAc to core 2 mucins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10052652" ], "products": [ "species_10076766", "species_205687" ], "modifiers": [ [ "species_10076770", "catalyst" ] ], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1N072", "ENSBTAT00000071114", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "G5E5A7", "ENSBTAT00000010897", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "ENSBTAT00000001899" ] }, "reaction_10070145": { "compartment": "compartment_12045", "id": "reaction_10070145", "reactome": "R-BTA-5173005", "name": "B3GALTL transfers glucose to O-fucosyl-proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070064", "species_173594" ], "products": [ "species_158602", "species_10070138" ], "modifiers": [ [ "species_10070142", "catalyst" ] ], "additional_components": [ "F1MXR3", "ENSBTAT00000081541", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BK41", "ENSBTAT00000061071", "E1BK41", "ENSBTAT00000061071", "F1MXR3", "ENSBTAT00000081541", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MVP0", "ENSBTAT00000020085", "A0A3Q1MX27", "ENSBTAT00000086844", "ENSBTAT00000047526" ] }, "reaction_10077897": { "compartment": "compartment_70101", "id": "reaction_10077897", "reactome": "R-BTA-6788855", "name": "FN3KRP phosphorylates PsiAm, RibAm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788865" ], "products": [ "species_6788858", "species_29370" ], "modifiers": [ [ "species_10077894", "catalyst" ] ], "additional_components": [ "CHEBI:87176", "CHEBI:87177", "CHEBI:87180", "CHEBI:87179", "ENSBTAT00000020456" ] }, "reaction_10077883": { "compartment": "compartment_12045", "id": "reaction_10077883", "reactome": "R-BTA-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_71285", "species_6788758" ], "modifiers": [ [ "species_10077880", "catalyst" ] ], "additional_components": [ "species_29426", "G3N1V4", "ENSBTAT00000064297" ] }, "reaction_10038408": { "compartment": "compartment_13959", "id": "reaction_10038408", "reactome": "R-BTA-159757", "name": "Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038406" ], "products": [ "species_10038394" ], "modifiers": [], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10038416": { "compartment": "compartment_13959", "id": "reaction_10038416", "reactome": "R-BTA-159783", "name": "Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038412" ], "products": [ "species_10038414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009746", "ENSBTAT00000009746" ] }, "reaction_10038438": { "compartment": "compartment_13959", "id": "reaction_10038438", "reactome": "R-BTA-159843", "name": "Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038436" ], "products": [ "species_10038384" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406" ] }, "reaction_10043698": { "compartment": "compartment_70101", "id": "reaction_10043698", "reactome": "R-BTA-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_204628", "species_73473" ], "products": [ "species_204635", "species_29360", "species_10043689" ], "modifiers": [ [ "species_10043695", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ6", "ENSBTAT00000008200" ] }, "reaction_10043717": { "compartment": "compartment_70101", "id": "reaction_10043717", "reactome": "R-BTA-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10043683", "species_29368", "species_73473" ], "products": [ "species_29356", "species_10043708", "species_29360" ], "modifiers": [ [ "species_10043714", "catalyst" ] ], "additional_components": [ "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q6EWQ7", "ENSBTAT00000084447", "F1MN49", "ENSBTAT00000079770", "Q0VC53", "ENSBTAT00000006935", "species_71067" ] }, "reaction_10060109": { "compartment": "compartment_17957", "id": "reaction_10060109", "reactome": "R-BTA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194653", "species_10060079" ], "products": [ "species_1663154", "species_194697", "species_10060106" ], "modifiers": [ [ "species_10060045", "catalyst" ] ], "additional_components": [ "F1N665", "ENSBTAT00000014061", "Q148F3", "ENSBTAT00000026877", "A0A3Q1LZ44", "ENSBTAT00000081469", "A6QLZ3", "ENSBTAT00000010988", "G3N2T7", "ENSBTAT00000072310", "A0A3Q1LGQ6", "ENSBTAT00000080500", "E1BIN3", "ENSBTAT00000017050", "A5D7J7", "ENSBTAT00000050377", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LZ44", "ENSBTAT00000081469", "F1N665", "ENSBTAT00000014061", "G3N2T7", "ENSBTAT00000072310", "A6QLZ3", "ENSBTAT00000010988", "E1BIN3", "ENSBTAT00000017050", "E1BKH3", "ENSBTAT00000023672", "A0A3Q1LGQ6", "ENSBTAT00000080500", "A5D7J7", "ENSBTAT00000050377", "Q148F3", "ENSBTAT00000026877", "ENSBTAT00000055237" ] }, "reaction_10091630": { "compartment": "compartment_17963", "id": "reaction_10091630", "reactome": "R-BTA-9668023", "name": "TPST1,2 transfer SO4(2-) from PAPS to FVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091620", "species_741440" ], "products": [ "species_742343", "species_10091628" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036726", "ENSBTAT00000036726", "ENSBTAT00000000502" ] }, "reaction_10071579": { "compartment": "compartment_70101", "id": "reaction_10071579", "reactome": "R-BTA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071569", "species_71284" ], "products": [ "species_10071572", "species_71285" ], "modifiers": [ [ "species_10071576", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000025327" ] }, "reaction_10071566": { "compartment": "compartment_70101", "id": "reaction_10071566", "reactome": "R-BTA-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071559", "species_113592", "species_31633" ], "products": [ "species_111294", "species_10038103", "species_76577" ], "modifiers": [ [ "species_10071563", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005581", "ENSBTAT00000005581", "ENSBTAT00000055382" ] }, "reaction_10066409": { "compartment": "compartment_7660", "id": "reaction_10066409", "reactome": "R-BTA-2993763", "name": "SENP1,2,5 proteolytically process SUMO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066405" ], "products": [ "species_10066407" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023029", "ENSBTAT00000023029", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066380": { "compartment": "compartment_7660", "id": "reaction_10066380", "reactome": "R-BTA-2990842", "name": "SENP1,2,5 proteolytically process SUMO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066376" ], "products": [ "species_10066378" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081472", "ENSBTAT00000081472", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10066372": { "compartment": "compartment_7660", "id": "reaction_10066372", "reactome": "R-BTA-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066355" ], "products": [ "species_10051814" ], "modifiers": [ [ "species_10066369", "catalyst" ] ], "additional_components": [ "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "A0A3Q1M137", "ENSBTAT00000084456", "A0A3Q1M2W5", "ENSBTAT00000084456", "A0A3Q1M4Y4", "ENSBTAT00000084456", "A0A3Q1MRS5", "ENSBTAT00000084456", "E1BAI5", "ENSBTAT00000002296", "A0A3Q1MTU0", "ENSBTAT00000080821", "A0A3Q1MFX1", "ENSBTAT00000078136" ] }, "reaction_10077406": { "compartment": "compartment_7660", "id": "reaction_10077406", "reactome": "R-BTA-6783238", "name": "OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056739", "species_10077402" ], "products": [ "species_10077404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055368", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "Q2TA10", "ENSBTAT00000055368" ] }, "reaction_10076001": { "compartment": "compartment_70101", "id": "reaction_10076001", "reactome": "R-BTA-5690870", "name": "OTUD7B,TNFAIP3 deubiquitinate TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075996" ], "products": [ "species_10052288", "species_10075998" ], "modifiers": [ [ "species_10075996", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10085345": { "compartment": "compartment_70101", "id": "reaction_10085345", "reactome": "R-BTA-8869506", "name": "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10085342" ], "products": [ "species_10039539", "species_10075998" ], "modifiers": [ [ "species_10085342", "catalyst" ] ], "additional_components": [ "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3ZCC3", "ENSBTAT00000021630", "E1B9S7", "ENSBTAT00000021435", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075952": { "compartment": "compartment_70101", "id": "reaction_10075952", "reactome": "R-BTA-5690827", "name": "TNFAIP3 (A20) ubiquitinates RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10075944" ], "products": [ "species_10075949" ], "modifiers": [ [ "species_10075944", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10075984": { "compartment": "compartment_70101", "id": "reaction_10075984", "reactome": "R-BTA-5690845", "name": "TNIPs bind TNFAIP3 (A20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037956", "species_10075980" ], "products": [ "species_10075982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069028", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "G3N2J6", "ENSBTAT00000064143", "E1BKS3", "ENSBTAT00000020124", "A0A3S5ZPJ2", "ENSBTAT00000016836", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10084931": { "compartment": "compartment_70101", "id": "reaction_10084931", "reactome": "R-BTA-8865182", "name": "OTUD7A hydrolyses K11diUb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075838" ], "products": [ "species_10033408" ], "modifiers": [ [ "species_10084928", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000009023" ] }, "reaction_10075970": { "compartment": "compartment_70101", "id": "reaction_10075970", "reactome": "R-BTA-5690843", "name": "OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075966", "species_10075962" ], "products": [ "species_10075968" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600", "Q3T0Y1", "ENSBTAT00000005174", "Q3T0Y1", "ENSBTAT00000005174", "P67939", "ENSBTAT00000001420", "Q3ZCC3", "ENSBTAT00000021630", "P61585", "ENSBTAT00000005600" ] }, "reaction_10075989": { "compartment": "compartment_70101", "id": "reaction_10075989", "reactome": "R-BTA-5690856", "name": "TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075986" ], "products": [ "species_10039539", "species_10075944" ], "modifiers": [ [ "species_10075986", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028", "Q3SZK6", "ENSBTAT00000008367", "A0A3Q1NKI9", "ENSBTAT00000069028" ] }, "reaction_10077371": { "compartment": "compartment_70101", "id": "reaction_10077371", "reactome": "R-BTA-6781899", "name": "USP13 binds SIAH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077367", "species_10054896" ], "products": [ "species_10077369" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061390", "ENSBTAT00000044404", "F1MBM6", "ENSBTAT00000044404", "E1BMF7", "ENSBTAT00000061390" ] }, "reaction_10077339": { "compartment": "compartment_70101", "id": "reaction_10077339", "reactome": "R-BTA-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077335", "species_10071514" ], "products": [ "species_10077337" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025198", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10075550": { "compartment": "compartment_7660", "id": "reaction_10075550", "reactome": "R-BTA-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075418" ], "products": [ "species_10075422", "species_10075547" ], "modifiers": [ [ "species_10075418", "catalyst" ] ], "additional_components": [ "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418", "F1N556", "ENSBTAT00000007177", "A6QLP0", "ENSBTAT00000006418", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N556", "ENSBTAT00000007177", "P67939", "ENSBTAT00000001420", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10075902": { "compartment": "compartment_7660", "id": "reaction_10075902", "reactome": "R-BTA-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075897" ], "products": [ "species_10036828", "species_10075899" ], "modifiers": [ [ "species_10075897", "catalyst" ] ], "additional_components": [ "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MY85", "ENSBTAT00000087113", "A0A3Q1MY85", "ENSBTAT00000087113" ] }, "reaction_10077393": { "compartment": "compartment_7660", "id": "reaction_10077393", "reactome": "R-BTA-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077388" ], "products": [ "species_10075488", "species_10077390" ], "modifiers": [ [ "species_10077388", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1LQ57", "ENSBTAT00000079478", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075891": { "compartment": "compartment_70101", "id": "reaction_10075891", "reactome": "R-BTA-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10075886" ], "products": [ "species_10033408", "species_10075888" ], "modifiers": [ [ "species_10075886", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1N3P2", "ENSBTAT00000026356" ] }, "reaction_10077363": { "compartment": "compartment_70101", "id": "reaction_10077363", "reactome": "R-BTA-6781897", "name": "USP11 deubiquitinates NFKBIA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077358" ], "products": [ "species_10077360", "species_10075884" ], "modifiers": [ [ "species_10077358", "catalyst" ] ], "additional_components": [ "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A5PKF9", "ENSBTAT00000022310", "Q8WNW7", "ENSBTAT00000022183" ] }, "reaction_10077331": { "compartment": "compartment_7660", "id": "reaction_10077331", "reactome": "R-BTA-5696958", "name": "USP44 deubiquitinates CDC20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077326" ], "products": [ "species_10077328", "species_10075547" ], "modifiers": [ [ "species_10077326", "catalyst" ] ], "additional_components": [ "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MRW5", "ENSBTAT00000077512", "E1BLZ0", "ENSBTAT00000026571" ] }, "reaction_10075561": { "compartment": "compartment_7660", "id": "reaction_10075561", "reactome": "R-BTA-5689973", "name": "USP10,USP24,USP42 deubiquitinate TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075556" ], "products": [ "species_10075558", "species_10075547" ], "modifiers": [ [ "species_10075556", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967", "A0A452DHT6", "ENSBTAT00000000967", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "A0A452DHT6", "ENSBTAT00000000967" ] }, "reaction_10077034": { "compartment": "compartment_70101", "id": "reaction_10077034", "reactome": "R-BTA-5696564", "name": "USP25 deubiquitinates DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077029" ], "products": [ "species_10077031", "species_10075884" ], "modifiers": [ [ "species_10077029", "catalyst" ] ], "additional_components": [ "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MMX0", "ENSBTAT00000075352", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MMX0", "ENSBTAT00000075352", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10077292": { "compartment": "compartment_17906", "id": "reaction_10077292", "reactome": "R-BTA-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077171" ], "products": [ "species_10077189", "species_10077289" ], "modifiers": [ [ "species_10077171", "catalyst" ] ], "additional_components": [ "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MSB6", "ENSBTAT00000029564", "A6H7B1", "ENSBTAT00000000733" ] }, "reaction_10077070": { "compartment": "compartment_70101", "id": "reaction_10077070", "reactome": "R-BTA-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077061" ], "products": [ "species_10075884", "species_10077067" ], "modifiers": [ [ "species_10077061", "catalyst" ] ], "additional_components": [ "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MKU1", "ENSBTAT00000061377", "E1BJZ0", "ENSBTAT00000010703", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172", "E1BJZ0", "ENSBTAT00000010703", "F1MKU1", "ENSBTAT00000061377", "A0A3Q1MC38", "ENSBTAT00000079399", "A0A3Q1MME1", "ENSBTAT00000043704", "A0A3Q1MAX7", "ENSBTAT00000031172" ] }, "reaction_10075808": { "compartment": "compartment_7660", "id": "reaction_10075808", "reactome": "R-BTA-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075801" ], "products": [ "species_10036828", "species_10075805" ], "modifiers": [ [ "species_10075801", "catalyst" ] ], "additional_components": [ "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438", "A0A3Q1N5C0", "ENSBTAT00000087295", "Q5EAE2", "ENSBTAT00000047754", "P0C8Z3", "ENSBTAT00000011818", "A5PJW1", "ENSBTAT00000000926", "E1BP59", "ENSBTAT00000061193", "E1BKJ5", "ENSBTAT00000009365", "G5E6P9", "ENSBTAT00000013438" ] }, "reaction_10077379": { "compartment": "compartment_7660", "id": "reaction_10077379", "reactome": "R-BTA-6781922", "name": "USP13 binds UFD1L:SKP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077375", "species_10077373" ], "products": [ "species_10077377" ], "modifiers": [], "additional_components": [ "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000061390", "E1BMF7", "ENSBTAT00000061390", "A7MB09", "ENSBTAT00000018036", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10077349": { "compartment": "compartment_70101", "id": "reaction_10077349", "reactome": "R-BTA-6781814", "name": "USP19 deubiquitinates RNF123", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10077344" ], "products": [ "species_10077346", "species_10039539" ], "modifiers": [ [ "species_10077344", "catalyst" ] ], "additional_components": [ "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "E1BL26", "ENSBTAT00000045376", "F1MUD4", "ENSBTAT00000025198" ] }, "reaction_10077317": { "compartment": "compartment_7660", "id": "reaction_10077317", "reactome": "R-BTA-5696914", "name": "USP28 deubiquitinates CLSPN and MYC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077308" ], "products": [ "species_10077314", "species_10075547" ], "modifiers": [ [ "species_10077308", "catalyst" ] ], "additional_components": [ "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1MAA7", "ENSBTAT00000081720", "A0A3Q1LF69", "ENSBTAT00000074281", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2HJ27", "ENSBTAT00000076263", "A0A3Q1LF69", "ENSBTAT00000074281", "A0A3Q1MAA7", "ENSBTAT00000081720" ] }, "reaction_10075374": { "compartment": "compartment_7660", "id": "reaction_10075374", "reactome": "R-BTA-5688786", "name": "ATXN3 binds RAD23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10075370" ], "products": [ "species_10075372" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10075397": { "compartment": "compartment_70101", "id": "reaction_10075397", "reactome": "R-BTA-5688797", "name": "ATXN3 family cleave Ub chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10039539" ], "products": [ "species_10039539", "species_10039537" ], "modifiers": [ [ "species_10075394", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "A0A3Q1MF75", "ENSBTAT00000067648", "A6H799", "ENSBTAT00000007611", "A0A3Q1M4J1", "ENSBTAT00000073722", "F1ME39", "ENSBTAT00000008984" ] }, "reaction_10086303": { "compartment": "compartment_7660", "id": "reaction_10086303", "reactome": "R-BTA-8932275", "name": "METTL22 transfers 3xCH3 from 3xAdoMet to KIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086293" ], "products": [ "species_77502", "species_10086296" ], "modifiers": [ [ "species_10086300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061405", "ENSBTAT00000061405", "ENSBTAT00000084035" ] }, "reaction_10086319": { "compartment": "compartment_70101", "id": "reaction_10086319", "reactome": "R-BTA-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_71285", "species_10086312" ], "modifiers": [ [ "species_10086316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000085737" ] }, "reaction_10086286": { "compartment": "compartment_70101", "id": "reaction_10086286", "reactome": "R-BTA-8931974", "name": "N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038086", "species_71284" ], "products": [ "species_10086279", "species_71285" ], "modifiers": [ [ "species_10086283", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087016", "ENSBTAT00000087016", "ENSBTAT00000065836" ] }, "reaction_10077744": { "compartment": "compartment_70101", "id": "reaction_10077744", "reactome": "R-BTA-6786205", "name": "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10037000" ], "products": [ "species_71285", "species_10077737" ], "modifiers": [ [ "species_10077741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044622", "ENSBTAT00000044622", "ENSBTAT00000046124" ] }, "reaction_10083231": { "compartment": "compartment_70101", "id": "reaction_10083231", "reactome": "R-BTA-6814418", "name": "PDCL promotes formation of G-beta:G-gamma heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037407", "species_10083225" ], "products": [ "species_10083229" ], "modifiers": [], "additional_components": [ "P63212", "ENSBTAT00000003959", "Q2HJA9", "ENSBTAT00000043370", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648" ] }, "reaction_10083808": { "compartment": "compartment_70101", "id": "reaction_10083808", "reactome": "R-BTA-8850560", "name": "G-protein alpha releases G-protein heterotrimer from PDCL ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083229", "species_10036952" ], "products": [ "species_10083806", "species_10083195" ], "modifiers": [], "additional_components": [ "Q2HJA9", "ENSBTAT00000043370", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "P63212", "ENSBTAT00000003959", "A5PKD6", "ENSBTAT00000083809", "P11017", "ENSBTAT00000008508", "A0A3Q1NGS8", "ENSBTAT00000082648", "ENSBTAT00000043370" ] }, "reaction_10077947": { "compartment": "compartment_3828046", "id": "reaction_10077947", "reactome": "R-BTA-6791016", "name": "SFTPB binds itself", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074840" ], "products": [ "species_10074859" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "P15781", "ENSBTAT00000045134" ] }, "reaction_10088922": { "compartment": "compartment_12045", "id": "reaction_10088922", "reactome": "R-BTA-8961021", "name": "SFTPD binds with itself to form SFTPD 12mer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088918" ], "products": [ "species_10088920" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074686": { "compartment": "compartment_2133233", "id": "reaction_10074686", "reactome": "R-BTA-5683714", "name": "ABCA3 transports PC, PG from ER membrane to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5684863" ], "products": [ "species_29372", "species_29370", "species_5684869" ], "modifiers": [ [ "species_10074683", "catalyst" ] ], "additional_components": [ "species_429785", "species_1602402", "species_429785", "species_1602402", "ENSBTAT00000019840" ] }, "reaction_10074833": { "compartment": "compartment_80738", "id": "reaction_10074833", "reactome": "R-BTA-5684862", "name": "SFTPB,C, PC, PG translocate from lamellar body to extracellular region.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074821", "species_10074817", "species_5684869" ], "products": [ "species_5686242", "species_10074827", "species_10074825" ], "modifiers": [ [ "species_10048001", "catalyst" ], [ "species_10046205", "catalyst" ], [ "species_10074831", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_429785", "species_1602402", "species_1602402", "species_429785", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "species_83909", "Q1LZD0", "ENSBTAT00000009974", "E1BKU0", "ENSBTAT00000077466", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789", "ENSBTAT00000035930" ] }, "reaction_10091120": { "compartment": "compartment_12045", "id": "reaction_10091120", "reactome": "R-BTA-9624778", "name": "SFTPD 12mer translocates from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088920" ], "products": [ "species_10075101" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "P35246", "ENSBTAT00000008579" ] }, "reaction_10074707": { "compartment": "compartment_7660", "id": "reaction_10074707", "reactome": "R-BTA-5683831", "name": "CCDC59 binds TTF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074703", "species_10074699" ], "products": [ "species_10074705" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024905", "ENSBTAT00000050784", "A5PJN1", "ENSBTAT00000050784", "E1B9V4", "ENSBTAT00000024905" ] }, "reaction_10074869": { "compartment": "compartment_12045", "id": "reaction_10074869", "reactome": "R-BTA-5684868", "name": "pro-SFTPC translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074865" ], "products": [ "species_10074867" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672" ] }, "reaction_10075125": { "compartment": "compartment_876", "id": "reaction_10075125", "reactome": "R-BTA-5686359", "name": "SFTPs translocate from extracellular region to clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075103" ], "products": [ "species_10075111", "species_10075123", "species_10075117", "species_10075099", "species_10075115" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134" ] }, "reaction_10091124": { "compartment": "compartment_12045", "id": "reaction_10091124", "reactome": "R-BTA-9624789", "name": "pro-SFTPB translocates from ER membrane to multivesicle body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091122" ], "products": [ "species_10074838" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134" ] }, "reaction_10075095": { "compartment": "compartment_876", "id": "reaction_10075095", "reactome": "R-BTA-5686304", "name": "ZDHHC2 transfers PALM from PALM-CoA to CKAP4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075088", "species_200993" ], "products": [ "species_10075070", "species_76194" ], "modifiers": [ [ "species_10075092", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015804", "ENSBTAT00000015804", "ENSBTAT00000064000" ] }, "reaction_10074857": { "compartment": "compartment_3828046", "id": "reaction_10074857", "reactome": "R-BTA-5684864", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074838", "species_5685882" ], "products": [ "species_10074844", "species_10074842", "species_10074840" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "ENSBTAT00000045134", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10075019": { "compartment": "compartment_12045", "id": "reaction_10075019", "reactome": "R-BTA-5685649", "name": "SFTPAs translocate from ER membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075015" ], "products": [ "species_10075017" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075084": { "compartment": "compartment_876", "id": "reaction_10075084", "reactome": "R-BTA-5686286", "name": "PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075072" ], "products": [ "species_10075082" ], "modifiers": [], "additional_components": [ "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804", "F1ME65", "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360" ] }, "reaction_10075023": { "compartment": "compartment_3828046", "id": "reaction_10075023", "reactome": "R-BTA-5685902", "name": "NAPSA, CTSH, PGA3-5 cleave pro-SFTPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5685882", "species_10074867" ], "products": [ "species_10075021", "species_10074861" ], "modifiers": [ [ "species_10074854", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016672", "ENSBTAT00000016672", "ENSBTAT00000016672", "E1BJW6", "ENSBTAT00000008917", "F1N373", "ENSBTAT00000019640" ] }, "reaction_10074863": { "compartment": "compartment_3828046", "id": "reaction_10074863", "reactome": "R-BTA-5684865", "name": "SFTPB dimer,C translocate from multivesicle body to lamellar body", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074861", "species_10074859" ], "products": [ "species_10074821", "species_10074817" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134", "ENSBTAT00000016672", "P15781", "ENSBTAT00000045134" ] }, "reaction_10075086": { "compartment": "compartment_876", "id": "reaction_10075086", "reactome": "R-BTA-5686301", "name": "PALM-C100-CKAP4 binds SFTPAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075070", "species_10075017" ], "products": [ "species_10075072" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015804", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "F1ME65", "ENSBTAT00000015804" ] }, "reaction_10075105": { "compartment": "compartment_876", "id": "reaction_10075105", "reactome": "R-BTA-5686335", "name": "CSF2RA:CSF2RB binds SFTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075101", "species_10074827", "species_10075099", "species_10074825", "species_10075017" ], "products": [ "species_10075103" ], "modifiers": [], "additional_components": [ "P35246", "ENSBTAT00000008579", "ENSBTAT00000016672", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "P15781", "ENSBTAT00000045134", "A0A3Q1NJ66", "ENSBTAT00000068360", "A0A3Q1NJ66", "ENSBTAT00000068360", "P15781", "ENSBTAT00000045134", "A0A3Q1MB14", "ENSBTAT00000040022", "F1MXH7", "ENSBTAT00000011947", "A0A452DJB4", "ENSBTAT00000016672", "P35246", "ENSBTAT00000008579" ] }, "reaction_10081291": { "compartment": "compartment_70101", "id": "reaction_10081291", "reactome": "R-BTA-6800797", "name": "The PIDDosome activates CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081288" ], "products": [ "species_10081284", "species_10043771", "species_10043769" ], "modifiers": [ [ "species_10081288", "catalyst" ] ], "additional_components": [ "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "ENSBTAT00000071790", "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081274": { "compartment": "compartment_7660", "id": "reaction_10081274", "reactome": "R-BTA-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10081269" ], "products": [ "species_113582", "species_10081272" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157", "ENSBTAT00000040104" ] }, "reaction_10081293": { "compartment": "compartment_70101", "id": "reaction_10081293", "reactome": "R-BTA-6800798", "name": "The PIDDosome binds CASP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043767", "species_10081284" ], "products": [ "species_10081288" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071790", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531", "A0A3Q1MIB8", "ENSBTAT00000071790" ] }, "reaction_10081278": { "compartment": "compartment_70101", "id": "reaction_10081278", "reactome": "R-BTA-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081272" ], "products": [ "species_10081276" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026157", "ENSBTAT00000026157" ] }, "reaction_10081286": { "compartment": "compartment_70101", "id": "reaction_10081286", "reactome": "R-BTA-6800794", "name": "PIDD1 associates with CRADD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081282", "species_10081276" ], "products": [ "species_10081284" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071531", "ENSBTAT00000026157", "G5E5N0", "ENSBTAT00000026157", "A0A3Q1MBQ2", "ENSBTAT00000071531" ] }, "reaction_10080457": { "compartment": "compartment_7660", "id": "reaction_10080457", "reactome": "R-BTA-6799097", "name": "ATM phosphorylates ZNF420", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10053725" ], "products": [ "species_113582", "species_10080455" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "A0A3Q1ML53", "ENSBTAT00000083153", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "A0A3Q1ML53", "ENSBTAT00000083153", "A0A3Q1MWH2", "ENSBTAT00000083153", "F1MJ74", "ENSBTAT00000083153", "F1N3X9", "ENSBTAT00000057355", "G3N3R0", "ENSBTAT00000083153", "A0A3Q1LXQ4", "ENSBTAT00000083153", "ENSBTAT00000040104" ] }, "reaction_10081305": { "compartment": "compartment_74700", "id": "reaction_10081305", "reactome": "R-BTA-6801195", "name": "STEAP3 binds BNIP3L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081301", "species_10052892" ], "products": [ "species_10081303" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033862", "ENSBTAT00000077862", "A0A3Q1LPT9", "ENSBTAT00000077862", "Q3T013", "ENSBTAT00000033862" ] }, "reaction_10081323": { "compartment": "compartment_17927", "id": "reaction_10081323", "reactome": "R-BTA-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081319", "species_10081309" ], "products": [ "species_10081321" ], "modifiers": [], "additional_components": [ "Q32KN9", "ENSBTAT00000006594", "ENSBTAT00000016994", "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10081326": { "compartment": "compartment_17906", "id": "reaction_10081326", "reactome": "R-BTA-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10081321", "catalyst" ] ], "additional_components": [ "Q0P5E1", "ENSBTAT00000016994", "Q32KN9", "ENSBTAT00000006594" ] }, "reaction_10080738": { "compartment": "compartment_70101", "id": "reaction_10080738", "reactome": "R-BTA-6799466", "name": "TP53I3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080734" ], "products": [ "species_10080736" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004413", "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10080789": { "compartment": "compartment_70101", "id": "reaction_10080789", "reactome": "R-BTA-6799722", "name": "TP53I3 oxidoreductase generates unstable semiquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6799725", "species_29364" ], "products": [ "species_6799726", "species_29366" ], "modifiers": [ [ "species_10080736", "catalyst" ] ], "additional_components": [ "Q0VC75", "ENSBTAT00000004413" ] }, "reaction_10056702": { "compartment": "compartment_70101", "id": "reaction_10056702", "reactome": "R-BTA-1234164", "name": "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056667" ], "products": [ "species_29434", "species_10056691", "species_113528" ], "modifiers": [ [ "species_10056699", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075132", "ENSBTAT00000075132", "species_198836", "species_71067", "F1MG82", "ENSBTAT00000000101" ] }, "reaction_10056679": { "compartment": "compartment_70101", "id": "reaction_10056679", "reactome": "R-BTA-1234161", "name": "HIF-alpha translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056671" ], "products": [ "species_10056677" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056761": { "compartment": "compartment_70101", "id": "reaction_10056761", "reactome": "R-BTA-1234183", "name": "Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056629", "species_10056659" ], "products": [ "species_10056685" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056719": { "compartment": "compartment_7660", "id": "reaction_10056719", "reactome": "R-BTA-1234165", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056675", "species_113671", "species_113685" ], "products": [ "species_10056704", "species_159942", "species_159939" ], "modifiers": [ [ "species_10056716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_71067", "A0A3Q1LUX2", "ENSBTAT00000072600", "species_198836", "A7MBA0", "ENSBTAT00000010744" ] }, "reaction_10056737": { "compartment": "compartment_7660", "id": "reaction_10056737", "reactome": "R-BTA-1234169", "name": "Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056723", "species_10056733" ], "products": [ "species_10056735" ], "modifiers": [], "additional_components": [ "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056688": { "compartment": "compartment_70101", "id": "reaction_10056688", "reactome": "R-BTA-1234163", "name": "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056685", "species_10056683" ], "products": [ "species_10056661", "species_10056681" ], "modifiers": [ [ "species_10056685", "catalyst" ] ], "additional_components": [ "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056754": { "compartment": "compartment_7660", "id": "reaction_10056754", "reactome": "R-BTA-1234172", "name": "Nuclear VBC complex ubiquitinylates HIF-alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056735", "species_10056747" ], "products": [ "species_10056751", "species_10056745" ], "modifiers": [ [ "species_10056735", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "Q2TA10", "ENSBTAT00000055368", "A0A3Q1M5N0", "ENSBTAT00000066609", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844" ] }, "reaction_10056757": { "compartment": "compartment_70101", "id": "reaction_10056757", "reactome": "R-BTA-1234173", "name": "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29368", "species_10056669" ], "products": [ "species_29434", "species_10056627", "species_113528" ], "modifiers": [ [ "species_10056659", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077844", "ENSBTAT00000077844", "species_198836", "species_71067", "A7MBA0", "ENSBTAT00000010744", "A0A3Q1M2B6", "ENSBTAT00000066920", "G5E5X0", "ENSBTAT00000037007", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10056759": { "compartment": "compartment_70101", "id": "reaction_10056759", "reactome": "R-BTA-1234175", "name": "ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056751" ], "products": [ "species_10056633" ], "modifiers": [], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MIU5", "ENSBTAT00000075132", "A0A3Q1MKG5", "ENSBTAT00000077844", "A0A3Q1LNF8", "ENSBTAT00000075328", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "E1BL53", "ENSBTAT00000030804" ] }, "reaction_10044776": { "compartment": "compartment_70101", "id": "reaction_10044776", "reactome": "R-BTA-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044772", "species_10033775" ], "products": [ "species_10044774" ], "modifiers": [], "additional_components": [ "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000005575", "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044794": { "compartment": "compartment_70101", "id": "reaction_10044794", "reactome": "R-BTA-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044774", "species_10044788" ], "products": [ "species_10044792" ], "modifiers": [], "additional_components": [ "P27117", "ENSBTAT00000005575", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466", "ENSBTAT00000072826", "P27117", "ENSBTAT00000005575", "A3KMV9", "ENSBTAT00000072826", "F1N021", "ENSBTAT00000044965", "A0A3Q1LX71", "ENSBTAT00000079466" ] }, "reaction_10044784": { "compartment": "compartment_70101", "id": "reaction_10044784", "reactome": "R-BTA-350578", "name": "NQO1 interaction with ODC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033775", "species_10044780" ], "products": [ "species_10044782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005575", "ENSBTAT00000079752", "A0A3Q1MK02", "ENSBTAT00000079752", "P27117", "ENSBTAT00000005575" ] }, "reaction_10047519": { "compartment": "compartment_70101", "id": "reaction_10047519", "reactome": "R-BTA-392513", "name": "Rap1 signal termination by Rap1GAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045005" ], "products": [ "species_111294", "species_10045007" ], "modifiers": [ [ "species_10047512", "catalyst" ], [ "species_10047517", "inhibitor" ] ], "additional_components": [ "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29438", "P61223", "ENSBTAT00000019575", "P62833", "ENSBTAT00000068678", "species_29420", "A0A3Q1MI55", "ENSBTAT00000066483", "A0A3Q1MTG9", "ENSBTAT00000077316", "A0A3Q1LME0", "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439" ] }, "reaction_10047536": { "compartment": "compartment_70101", "id": "reaction_10047536", "reactome": "R-BTA-392834", "name": "Activation of EPACs by cAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10047532" ], "products": [ "species_10047534" ], "modifiers": [], "additional_components": [ "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "E1BPX7", "ENSBTAT00000061074", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389" ] }, "reaction_10052466": { "compartment": "compartment_70101", "id": "reaction_10052466", "reactome": "R-BTA-913993", "name": "14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_10047515" ], "products": [ "species_10047517" ], "modifiers": [ [ "species_10052464", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000075439", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "A0A3Q1LME0", "ENSBTAT00000075439", "ENSBTAT00000075439" ] }, "reaction_10052471": { "compartment": "compartment_70101", "id": "reaction_10052471", "reactome": "R-BTA-913996", "name": "PKA/PKG phosphorylate Rap1GAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047510", "species_113592" ], "products": [ "species_29370", "species_10052464" ], "modifiers": [ [ "species_427893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075439", "ENSBTAT00000075439", "ENSBTAT00000030539" ] }, "reaction_10071800": { "compartment": "compartment_70101", "id": "reaction_10071800", "reactome": "R-BTA-5577050", "name": "AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071797", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1LPA7", "ENSBTAT00000069177" ] }, "reaction_10059961": { "compartment": "compartment_70101", "id": "reaction_10059961", "reactome": "R-BTA-1605723", "name": "Neu5Ac is cleaved from GM3 by NEU2 to form a globoside (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605590", "species_29356" ], "products": [ "species_428633", "species_1605647" ], "modifiers": [ [ "species_10059958", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027552" ] }, "reaction_10071483": { "compartment": "compartment_70101", "id": "reaction_10071483", "reactome": "R-BTA-5339535", "name": "GLTPD1 transports C1P from plasma membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1638840" ], "products": [ "species_5339515" ], "modifiers": [ [ "species_10071480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010025" ] }, "reaction_10084410": { "compartment": "compartment_20699", "id": "reaction_10084410", "reactome": "R-BTA-8856223", "name": "B4GALNT1 dimer transfers GalNAc from UDP-GalNAc to GM3 and GD3 gangliosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_8856243" ], "products": [ "species_8856242", "species_205687" ], "modifiers": [ [ "species_10084407", "catalyst" ] ], "additional_components": [ "species_1605641", "CHEBI:28424", "species_1605610", "CHEBI:28648", "Q58DI2", "ENSBTAT00000005893" ] }, "reaction_10060316": { "compartment": "compartment_876", "id": "reaction_10060316", "reactome": "R-BTA-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060313", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002552" ] }, "reaction_10059984": { "compartment": "compartment_70101", "id": "reaction_10059984", "reactome": "R-BTA-1605768", "name": "Neu5Ac is cleaved from GM3 by NEU3 to form globoside (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1605649" ], "products": [ "species_428633", "species_1605618" ], "modifiers": [ [ "species_10059981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000036738" ] }, "reaction_10059954": { "compartment": "compartment_161320", "id": "reaction_10059954", "reactome": "R-BTA-1605717", "name": "Ganglioside GM2 activator presents GM2 to hexosaminidase for cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059927", "species_1605610" ], "products": [ "species_10059929" ], "modifiers": [ [ "species_10059927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029099", "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099" ] }, "reaction_10060021": { "compartment": "compartment_876", "id": "reaction_10060021", "reactome": "R-BTA-1606583", "name": "Neutral ceramidase hydrolyses ceramide into sphingosine and free fatty acid (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429807" ], "products": [ "species_1606609", "species_1861754" ], "modifiers": [ [ "species_10060018", "catalyst" ] ], "additional_components": [] }, "reaction_10060309": { "compartment": "compartment_876", "id": "reaction_10060309", "reactome": "R-BTA-1638845", "name": "CERK phosphorylates CERA to form C1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429807", "species_113592" ], "products": [ "species_29370", "species_1638840" ], "modifiers": [ [ "species_10060306", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064397" ] }, "reaction_10059991": { "compartment": "compartment_161320", "id": "reaction_10059991", "reactome": "R-BTA-1605797", "name": "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605713" ], "products": [ "species_1605750", "species_1605673" ], "modifiers": [ [ "species_10059988", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020758" ] }, "reaction_10059977": { "compartment": "compartment_161320", "id": "reaction_10059977", "reactome": "R-BTA-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605637", "species_1605601" ], "modifiers": [ [ "species_10059974", "catalyst" ] ], "additional_components": [ "E1B725", "ENSBTAT00000025636" ] }, "reaction_10060041": { "compartment": "compartment_12045", "id": "reaction_10060041", "reactome": "R-BTA-1606839", "name": "Steryl sulfatase hydrolyses sulfate from steroid sulfates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_1609648" ], "products": [ "species_1609650", "species_1609649" ], "modifiers": [ [ "species_10060038", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LZ44", "ENSBTAT00000081469" ] }, "reaction_10071497": { "compartment": "compartment_876", "id": "reaction_10071497", "reactome": "R-BTA-5340320", "name": "GLTP transports GSL from plasma membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5340315" ], "products": [ "species_5340299" ], "modifiers": [ [ "species_10071494", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003355" ] }, "reaction_10059944": { "compartment": "compartment_161320", "id": "reaction_10059944", "reactome": "R-BTA-1605595", "name": "Hexosaminidase A cleaves GalNAc from GM2 to form GM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10059929" ], "products": [ "species_10059927", "species_1605658", "species_1605641" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "species_1605610", "E1BI28", "ENSBTAT00000029099", "ENSBTAT00000029099", "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060012": { "compartment": "compartment_876", "id": "reaction_10060012", "reactome": "R-BTA-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429776" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10060009", "catalyst" ] ], "additional_components": [ "species_29926", "F1N588", "ENSBTAT00000010706" ] }, "reaction_10059951": { "compartment": "compartment_161320", "id": "reaction_10059951", "reactome": "R-BTA-1605632", "name": "Both hexosaminidase A and B can cleave GalNAc from globoside", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605608" ], "products": [ "species_1605716", "species_1605658" ], "modifiers": [ [ "species_10059948", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411", "Q0V8R6", "ENSBTAT00000017261" ] }, "reaction_10060302": { "compartment": "compartment_20699", "id": "reaction_10060302", "reactome": "R-BTA-1638104", "name": "Ceramide glucosyltransferase (UGCG) catalyses the transfer of glucose to ceramide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_744227", "species_428270" ], "products": [ "species_1660674", "species_205687" ], "modifiers": [ [ "species_10060299", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043826" ] }, "reaction_10059968": { "compartment": "compartment_161320", "id": "reaction_10059968", "reactome": "R-BTA-1605724", "name": "Neu5Ac is cleaved from GM3 by NEU1 and 4 to form a globoside (lysosomal lumen)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_1605641" ], "products": [ "species_1605601", "species_428639" ], "modifiers": [ [ "species_10059965", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019755" ] }, "reaction_10048986": { "compartment": "compartment_70101", "id": "reaction_10048986", "reactome": "R-BTA-428676", "name": "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_428671", "species_428686" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049116": { "compartment": "compartment_12045", "id": "reaction_10049116", "reactome": "R-BTA-429683", "name": "CERT:ceramide [ER] => ceramide [Golgi] + CERT [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049108" ], "products": [ "species_10049110", "species_428270" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000027095" ] }, "reaction_10048860": { "compartment": "compartment_70101", "id": "reaction_10048860", "reactome": "R-BTA-428127", "name": "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_9695889" ], "products": [ "species_113528", "species_76194", "species_428182" ], "modifiers": [ [ "species_10048843", "catalyst" ], [ "species_10048858", "inhibitor" ] ], "additional_components": [ "Q5E978", "ENSBTAT00000018578", "Q0IIK4", "ENSBTAT00000085219", "Q3MHG1", "ENSBTAT00000002872", "A5PKM3", "ENSBTAT00000027289", "Q0VD15", "ENSBTAT00000018402", "Q29RQ9", "ENSBTAT00000016673", "Q5E972", "ENSBTAT00000027540" ] }, "reaction_10048988": { "compartment": "compartment_70101", "id": "reaction_10048988", "reactome": "R-BTA-428681", "name": "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275" ], "products": [ "species_428686", "species_428663" ], "modifiers": [ [ "species_10048983", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080801" ] }, "reaction_10049182": { "compartment": "compartment_876", "id": "reaction_10049182", "reactome": "R-BTA-429786", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_429807" ], "products": [ "species_429776", "species_112275" ], "modifiers": [ [ "species_10049179", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072919" ] }, "reaction_10048978": { "compartment": "compartment_70101", "id": "reaction_10048978", "reactome": "R-BTA-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428275" ], "products": [ "species_29372", "species_428694" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10048917": { "compartment": "compartment_70101", "id": "reaction_10048917", "reactome": "R-BTA-428262", "name": "phytoceramide + H2O => stearate + phytosphingosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9025544" ], "products": [ "species_428237", "species_3632878" ], "modifiers": [ [ "species_10048914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052101" ] }, "reaction_10049161": { "compartment": "compartment_70101", "id": "reaction_10049161", "reactome": "R-BTA-429730", "name": "multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049158", "species_29356" ], "products": [ "species_10049110", "species_29372" ], "modifiers": [ [ "species_10049158", "catalyst" ] ], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10049163": { "compartment": "compartment_70101", "id": "reaction_10049163", "reactome": "R-BTA-429732", "name": "multiphospho-CERT + PPM1L:VAPA/B => multiphospho-CERT:PPM1L:VAPA/B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049100", "species_10049147" ], "products": [ "species_10049158" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10082058": { "compartment": "compartment_13977", "id": "reaction_10082058", "reactome": "R-BTA-6808464", "name": "ALDH3B2 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6808468", "species_29360" ], "products": [ "species_2453691", "species_70106", "species_73473" ], "modifiers": [ [ "species_10082055", "catalyst" ] ], "additional_components": [ "A0A3Q1M3Q4", "ENSBTAT00000085198", "Q1JPA0", "ENSBTAT00000076578" ] }, "reaction_10048910": { "compartment": "compartment_70101", "id": "reaction_10048910", "reactome": "R-BTA-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428126", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9025544" ], "modifiers": [ [ "species_10048907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012243" ] }, "reaction_10048896": { "compartment": "compartment_70101", "id": "reaction_10048896", "reactome": "R-BTA-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428163" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10048893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074462" ] }, "reaction_10049154": { "compartment": "compartment_70101", "id": "reaction_10049154", "reactome": "R-BTA-429714", "name": "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049124", "species_113592" ], "products": [ "species_29370", "species_10049147" ], "modifiers": [ [ "species_10049151", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "ENSBTAT00000022345" ] }, "reaction_10048903": { "compartment": "compartment_70101", "id": "reaction_10048903", "reactome": "R-BTA-428231", "name": "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428256" ], "products": [ "species_428193", "species_428198" ], "modifiers": [ [ "species_10048900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010648" ] }, "reaction_10048889": { "compartment": "compartment_20699", "id": "reaction_10048889", "reactome": "R-BTA-428205", "name": "ceramide + H2O => stearate + sphingosine [Golgi]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428270" ], "products": [ "species_428248", "species_8934421" ], "modifiers": [ [ "species_10048886", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014354" ] }, "reaction_10048882": { "compartment": "compartment_70101", "id": "reaction_10048882", "reactome": "R-BTA-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428139", "species_428163" ], "products": [ "species_428126", "species_76194" ], "modifiers": [ [ "species_10048879", "catalyst" ] ], "additional_components": [ "A0A3Q1MVP2", "ENSBTAT00000082150", "A0A3Q1MJ30", "ENSBTAT00000080491", "A4FUG2", "ENSBTAT00000036524", "A5D7K4", "ENSBTAT00000052579" ] }, "reaction_10049141": { "compartment": "compartment_70101", "id": "reaction_10049141", "reactome": "R-BTA-429698", "name": "PRKD1,2,3 phosphorylates COL4A3BP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049119" ], "products": [ "species_10049124", "species_29370" ], "modifiers": [ [ "species_10049138", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056797", "ENSBTAT00000056797", "A0A3Q1N9F5", "ENSBTAT00000081006", "F1MIA2", "ENSBTAT00000020721", "E1B7L9", "ENSBTAT00000070039" ] }, "reaction_10049143": { "compartment": "compartment_12045", "id": "reaction_10049143", "reactome": "R-BTA-429699", "name": "CERT [ER] + ceramide [ER] => CERT:ceramide [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110", "species_428256" ], "products": [ "species_10049108" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "species_428256", "Q9GKI7", "ENSBTAT00000056797" ] }, "reaction_10076151": { "compartment": "compartment_12045", "id": "reaction_10076151", "reactome": "R-BTA-5692261", "name": "ALDH3A2-1 oxidises HD2NAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428671", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076148", "catalyst" ] ], "additional_components": [ "A0A3Q1LJ52", "ENSBTAT00000070862" ] }, "reaction_10049004": { "compartment": "compartment_70101", "id": "reaction_10049004", "reactome": "R-BTA-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10049001", "catalyst" ] ], "additional_components": [ "A0A3Q1MIK4", "ENSBTAT00000069794", "Q3SZE3", "ENSBTAT00000015460" ] }, "reaction_10049007": { "compartment": "compartment_70101", "id": "reaction_10049007", "reactome": "R-BTA-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10048975", "catalyst" ] ], "additional_components": [ "A0JNA1", "ENSBTAT00000005808", "A0A3Q1N0W7", "ENSBTAT00000067390" ] }, "reaction_10049121": { "compartment": "compartment_70101", "id": "reaction_10049121", "reactome": "R-BTA-429694", "name": "CERT:PPM1L:VAPA/B [ER] => CERT [cytosol] + PPM1L:VAPA/B [ER]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049110" ], "products": [ "species_10049119", "species_10049100" ], "modifiers": [], "additional_components": [ "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250", "Q9GKI7", "ENSBTAT00000056797", "ENSBTAT00000056797", "A2VDZ9", "ENSBTAT00000023164", "A0A452DJG0", "ENSBTAT00000053250" ] }, "reaction_10076833": { "compartment": "compartment_876", "id": "reaction_10076833", "reactome": "R-BTA-5696080", "name": "ALDH3B1 oxidises HXAL to PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428663", "species_29360" ], "products": [ "species_70106", "species_3632881", "species_73473" ], "modifiers": [ [ "species_10076830", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076578" ] }, "reaction_10091936": { "compartment": "compartment_70101", "id": "reaction_10091936", "reactome": "R-BTA-9695890", "name": "SPNS2 transports S1P from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203" ], "products": [ "species_419305" ], "modifiers": [ [ "species_10091933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009765" ] }, "reaction_10048995": { "compartment": "compartment_984", "id": "reaction_10048995", "reactome": "R-BTA-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10048992", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069794" ] }, "reaction_10076389": { "compartment": "compartment_12045", "id": "reaction_10076389", "reactome": "R-BTA-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10076386", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016212" ] }, "reaction_10049189": { "compartment": "compartment_20699", "id": "reaction_10049189", "reactome": "R-BTA-429798", "name": "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_428270" ], "products": [ "species_429773", "species_429789" ], "modifiers": [ [ "species_10049186", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082007" ] }, "reaction_10091941": { "compartment": "compartment_70101", "id": "reaction_10091941", "reactome": "R-BTA-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_428203", "species_29370" ], "modifiers": [ [ "species_10048893", "catalyst" ], [ "species_10091939", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000074462", "A0A3Q1MBG6", "ENSBTAT00000074462" ] }, "reaction_10043933": { "compartment": "compartment_70101", "id": "reaction_10043933", "reactome": "R-BTA-209823", "name": "Tyrosine is hydroxylated to dopa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29368", "species_29506" ], "products": [ "species_209849", "species_71112" ], "modifiers": [ [ "species_10043930", "catalyst" ] ], "additional_components": [ "A0A3Q1MAN0", "ENSBTAT00000077835", "species_71067" ] }, "reaction_10073477": { "compartment": "compartment_5668572", "id": "reaction_10073477", "reactome": "R-BTA-5662660", "name": "Dopachrome is transformed to DHICA by DCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5662665" ], "products": [ "species_5662670" ], "modifiers": [ [ "species_10073474", "catalyst" ] ], "additional_components": [ "F1MC37", "ENSBTAT00000034881", "species_29426" ] }, "reaction_10044216": { "compartment": "compartment_17960", "id": "reaction_10044216", "reactome": "R-BTA-211924", "name": "CYP4B1 12-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215075" ], "modifiers": [ [ "species_10044213", "catalyst" ] ], "additional_components": [ "Q148E6", "ENSBTAT00000015892" ] }, "reaction_10044195": { "compartment": "compartment_17960", "id": "reaction_10044195", "reactome": "R-BTA-211904", "name": "CYP4F12 18-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_352318" ], "modifiers": [ [ "species_10044192", "catalyst" ] ], "additional_components": [ "A0A3Q1MU89", "ENSBTAT00000072981", "F1MCD3", "ENSBTAT00000036364", "A0A3Q1MCJ2", "ENSBTAT00000073532", "M0QW30", "ENSBTAT00000072981" ] }, "reaction_10044260": { "compartment": "compartment_17960", "id": "reaction_10044260", "reactome": "R-BTA-211983", "name": "CYP2J2 oxidises ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215062" ], "modifiers": [ [ "species_10044257", "catalyst" ] ], "additional_components": [ "CHEBI:34130", "CHEBI:34157", "species_2142739", "CHEBI:34490", "F1N3N3", "ENSBTAT00000051914", "M0QW09", "ENSBTAT00000018202" ] }, "reaction_10035958": { "compartment": "compartment_17960", "id": "reaction_10035958", "reactome": "R-BTA-76466", "name": "CYP4A11 12-hydroxylates DDCX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_33549", "species_113601" ], "products": [ "species_113519", "species_113564", "species_42373" ], "modifiers": [ [ "species_10035955", "catalyst" ] ], "additional_components": [ "F1N3I8", "ENSBTAT00000021785" ] }, "reaction_10048504": { "compartment": "compartment_876", "id": "reaction_10048504", "reactome": "R-BTA-425661", "name": "SLC8A1,2,3 exchange 3Na+ for Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_74113" ], "products": [ "species_83910", "species_74112" ], "modifiers": [ [ "species_10048501", "catalyst" ], [ "species_10037000", "inhibitor" ] ], "additional_components": [ "E1B7D0", "ENSBTAT00000014410", "A0A3Q1LST7", "ENSBTAT00000077819", "ENSBTAT00000044622" ] }, "reaction_10072522": { "compartment": "compartment_263163", "id": "reaction_10072522", "reactome": "R-BTA-5626316", "name": "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5626313", "species_83910", "species_167012" ], "products": [ "species_29804", "species_74016", "species_425958" ], "modifiers": [ [ "species_10072519", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006382" ] }, "reaction_10048526": { "compartment": "compartment_876", "id": "reaction_10048526", "reactome": "R-BTA-425678", "name": "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_74016", "species_74113" ], "products": [ "species_74126", "species_83910", "species_74112" ], "modifiers": [ [ "species_10048523", "catalyst" ] ], "additional_components": [ "F1MD60", "ENSBTAT00000008703", "A0A3Q1M073", "ENSBTAT00000074844", "E1BM98", "ENSBTAT00000061324", "E1BGG7", "ENSBTAT00000015768" ] }, "reaction_10048533": { "compartment": "compartment_876", "id": "reaction_10048533", "reactome": "R-BTA-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425815", "species_74016" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10048530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10038895": { "compartment": "compartment_70616", "id": "reaction_10038895", "reactome": "R-BTA-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_113529", "species_29362" ], "products": [ "species_76633", "species_113526", "species_163953" ], "modifiers": [ [ "species_10038882", "catalyst" ], [ "species_10038893", "catalyst" ] ], "additional_components": [ "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219", "Q85BD6", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "P03910", "ENSBTAT00000060552", "F1MK72", "ENSBTAT00000006115", "Q1RMM6", "ENSBTAT00000005722" ] }, "reaction_10080521": { "compartment": "compartment_70616", "id": "reaction_10080521", "reactome": "R-BTA-6799202", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080503", "species_10080485" ], "products": [ "species_10080505" ], "modifiers": [], "additional_components": [ "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10080515": { "compartment": "compartment_70616", "id": "reaction_10080515", "reactome": "R-BTA-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038704", "species_10080511", "species_10080507" ], "products": [ "species_10080513" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077219", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552", "P23934", "ENSBTAT00000013078", "P04394", "ENSBTAT00000006405", "A0A3Q1M7B1", "ENSBTAT00000065530", "A0A3Q1N0E1", "ENSBTAT00000065530", "P15690", "ENSBTAT00000029301", "A0A452DIK0", "ENSBTAT00000019529", "species_73524", "A0A3Q1MG52", "ENSBTAT00000075840", "Q02379", "ENSBTAT00000077219" ] }, "reaction_10080517": { "compartment": "compartment_70616", "id": "reaction_10080517", "reactome": "R-BTA-6799197", "name": "ND4, ND5 bind the 550kDa complex to form the 815kDa complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038708", "species_10038712", "species_10080505" ], "products": [ "species_10080507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060552", "ENSBTAT00000060577", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q6QTH1", "ENSBTAT00000060571", "P42026", "ENSBTAT00000053067", "P34943", "ENSBTAT00000007189", "species_113596", "Q2HJI2", "ENSBTAT00000025174", "A4FUH5", "ENSBTAT00000004122", "Q02374", "ENSBTAT00000029003", "A0A3Q1LFL6", "ENSBTAT00000035646", "A0A3Q1MFA0", "ENSBTAT00000071194", "A0A3Q1M144", "ENSBTAT00000071194", "Q02377", "ENSBTAT00000007925", "Q02365", "ENSBTAT00000016957", "Q02827", "ENSBTAT00000024209", "P23935", "ENSBTAT00000012287", "A0A3Q1LW79", "ENSBTAT00000067852", "P42029", "ENSBTAT00000005628", "Q02369", "ENSBTAT00000027191", "G3X6L0", "ENSBTAT00000008382", "Q02373", "ENSBTAT00000012542", "A0A452DIB4", "ENSBTAT00000012512", "Q02368", "ENSBTAT00000016768", "Q8HXG5", "ENSBTAT00000070642", "Q05752", "ENSBTAT00000077911", "Q02372", "ENSBTAT00000000100", "Q02370", "ENSBTAT00000020018", "A0A3Q1LID6", "ENSBTAT00000072963", "Q95KV7", "ENSBTAT00000010276", "Q02371", "ENSBTAT00000010193", "Q02380", "ENSBTAT00000003197", "Q8HXG6", "ENSBTAT00000025322", "A7YVD7", "ENSBTAT00000009959", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "Q85BD6", "ENSBTAT00000060577", "P03910", "ENSBTAT00000060552" ] }, "reaction_10080519": { "compartment": "compartment_70616", "id": "reaction_10080519", "reactome": "R-BTA-6799199", "name": "COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038740", "species_10080501", "species_10038720", "species_10038716", "species_10038730" ], "products": [ "species_10080503" ], "modifiers": [], "additional_components": [ "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "ENSBTAT00000007761", "ENSBTAT00000060562", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "A0A3Q1MBM6", "ENSBTAT00000084872", "Q6QTH0", "ENSBTAT00000060548", "P03924", "ENSBTAT00000060562", "Q02367", "ENSBTAT00000007761", "A0A3Q1MP25", "ENSBTAT00000085097", "Q3SX05", "ENSBTAT00000020029", "E1BAZ2", "ENSBTAT00000074751", "E1BCS4", "ENSBTAT00000027441", "P03898", "ENSBTAT00000060547", "Q5EA03", "ENSBTAT00000030501" ] }, "reaction_10038647": { "compartment": "compartment_70616", "id": "reaction_10038647", "reactome": "R-BTA-163214", "name": "Electron transfer from reduced cytochrome c to molecular oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10038546", "species_113529" ], "products": [ "species_10038548", "species_163953", "species_113521" ], "modifiers": [ [ "species_10038606", "catalyst" ], [ "species_10038643", "catalyst" ], [ "species_10038611", "catalyst" ], [ "species_10038625", "catalyst" ], [ "species_10038645", "inhibitor" ] ], "additional_components": [ "CHEBI:38573", "P62894", "ENSBTAT00000007918", "P62894", "ENSBTAT00000007918", "CHEBI:38574", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "A6H784", "ENSBTAT00000016742", "A0A3Q1MQS6", "ENSBTAT00000067855", "E1BJK7", "ENSBTAT00000013031", "E1BPX9", "ENSBTAT00000021773", "ENSBTAT00000020289", "A0A3Q1MMW4", "ENSBTAT00000082257", "F1N5P2", "ENSBTAT00000007094", "Q1RMH3", "ENSBTAT00000001069", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10084313": { "compartment": "compartment_70101", "id": "reaction_10084313", "reactome": "R-BTA-8854981", "name": "SHC1 in the RET complex is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084133" ], "products": [ "species_10074027" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084185": { "compartment": "compartment_70101", "id": "reaction_10084185", "reactome": "R-BTA-8853774", "name": "GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084177" ], "products": [ "species_10084183", "species_29370" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084153": { "compartment": "compartment_70101", "id": "reaction_10084153", "reactome": "R-BTA-8853755", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043197", "species_10074025" ], "products": [ "species_10084151" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10085755": { "compartment": "compartment_876", "id": "reaction_10085755", "reactome": "R-BTA-8871226", "name": "RET binds GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074005", "species_10084137" ], "products": [ "species_10084157" ], "modifiers": [], "additional_components": [ "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398" ] }, "reaction_10084187": { "compartment": "compartment_984", "id": "reaction_10084187", "reactome": "R-BTA-8853789", "name": "GDNF,NRTN bind RET:GFRA1,GFRA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073999", "species_10084157" ], "products": [ "species_10084159" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528" ] }, "reaction_10084379": { "compartment": "compartment_70101", "id": "reaction_10084379", "reactome": "R-BTA-8855747", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084375", "species_10074025" ], "products": [ "species_10084377" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1BIM8", "ENSBTAT00000011767", "A0A3Q1MTG9", "ENSBTAT00000077316" ] }, "reaction_10085757": { "compartment": "compartment_876", "id": "reaction_10085757", "reactome": "R-BTA-8871227", "name": "RET binds GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074017", "species_10084137" ], "products": [ "species_10084161" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066172", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084190": { "compartment": "compartment_876", "id": "reaction_10084190", "reactome": "R-BTA-8853792", "name": "RET tyrosine phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084167", "species_113592" ], "products": [ "species_29370", "species_10074025" ], "modifiers": [ [ "species_10084167", "catalyst" ] ], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084309": { "compartment": "compartment_70101", "id": "reaction_10084309", "reactome": "R-BTA-8854897", "name": "p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043811", "species_10084175" ], "products": [ "species_10084177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10084149": { "compartment": "compartment_70101", "id": "reaction_10084149", "reactome": "R-BTA-8853753", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10074025" ], "products": [ "species_10084147" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10084311": { "compartment": "compartment_70101", "id": "reaction_10084311", "reactome": "R-BTA-8854899", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074025" ], "products": [ "species_10074031" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084169": { "compartment": "compartment_876", "id": "reaction_10084169", "reactome": "R-BTA-8853762", "name": "RET dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084165" ], "products": [ "species_10084167" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553", "A0A3Q1M0Y1", "ENSBTAT00000081398", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084393": { "compartment": "compartment_70101", "id": "reaction_10084393", "reactome": "R-BTA-8855915", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084389", "species_10074025" ], "products": [ "species_10084391" ], "modifiers": [], "additional_components": [ "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q3SX40", "ENSBTAT00000009662", "A5PKJ4", "ENSBTAT00000001347", "F1MP52", "ENSBTAT00000015112", "F1MJE0", "ENSBTAT00000015938" ] }, "reaction_10084330": { "compartment": "compartment_984", "id": "reaction_10084330", "reactome": "R-BTA-8855564", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind FRS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072959", "species_10074025" ], "products": [ "species_10084328" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025495", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "E1B7I9", "ENSBTAT00000025495" ] }, "reaction_10084141": { "compartment": "compartment_876", "id": "reaction_10084141", "reactome": "R-BTA-8853745", "name": "RET binds GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073976", "species_10084137" ], "products": [ "species_10084139" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083411", "ENSBTAT00000000744", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411" ] }, "reaction_10084352": { "compartment": "compartment_70101", "id": "reaction_10084352", "reactome": "R-BTA-8855617", "name": "2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084348", "species_10074025" ], "products": [ "species_10084350" ], "modifiers": [], "additional_components": [ "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "G3N3X9", "ENSBTAT00000064953", "A7MBB8", "ENSBTAT00000004337", "A4IFJ7", "ENSBTAT00000071968", "Q0VCR5", "ENSBTAT00000064819" ] }, "reaction_10084131": { "compartment": "compartment_70101", "id": "reaction_10084131", "reactome": "R-BTA-8853734", "name": "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10074027" ], "products": [ "species_10074029" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084194": { "compartment": "compartment_70101", "id": "reaction_10084194", "reactome": "R-BTA-8853793", "name": "p-5Y-RET complexes bind GRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084192", "species_10035485" ], "products": [ "species_10084175" ], "modifiers": [], "additional_components": [ "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "ENSBTAT00000006216", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10084196": { "compartment": "compartment_984", "id": "reaction_10084196", "reactome": "R-BTA-8853800", "name": "ARTN binds RET:GFRA1,GFRA3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073972", "species_10084139" ], "products": [ "species_10084155" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023553", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "E1BD76", "ENSBTAT00000023553" ] }, "reaction_10084135": { "compartment": "compartment_70101", "id": "reaction_10084135", "reactome": "R-BTA-8853737", "name": "2x p-5Y-RET:GDNF:GFRA complexes bind SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035544", "species_10074025" ], "products": [ "species_10084133" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075224", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224" ] }, "reaction_10084198": { "compartment": "compartment_984", "id": "reaction_10084198", "reactome": "R-BTA-8853801", "name": "PSPN binds RET:GFRA4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084161", "species_10074013" ], "products": [ "species_10084163" ], "modifiers": [], "additional_components": [ "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172", "ENSBTAT00000027984", "E1BCL0", "ENSBTAT00000027984", "F1MS00", "ENSBTAT00000000744", "G3MZM3", "ENSBTAT00000066172" ] }, "reaction_10084326": { "compartment": "compartment_876", "id": "reaction_10084326", "reactome": "R-BTA-8855508", "name": "p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10084183" ], "products": [ "species_10084324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F6S0Q2", "ENSBTAT00000006816", "E1BKU1", "ENSBTAT00000000528", "F1MS00", "ENSBTAT00000000744", "A0A3Q1N8H3", "ENSBTAT00000083411", "A0A3Q1M0Y1", "ENSBTAT00000081398", "E1BD76", "ENSBTAT00000023553", "E1BCL0", "ENSBTAT00000027984", "G3MZM3", "ENSBTAT00000066172", "Q0IIE2", "ENSBTAT00000075224", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10061049": { "compartment": "compartment_7660", "id": "reaction_10061049", "reactome": "R-BTA-1855206", "name": "I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023891" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061017": { "compartment": "compartment_7660", "id": "reaction_10061017", "reactome": "R-BTA-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061128": { "compartment": "compartment_7660", "id": "reaction_10061128", "reactome": "R-BTA-1855228", "name": "I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023892" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10061131": { "compartment": "compartment_7660", "id": "reaction_10061131", "reactome": "R-BTA-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023922" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061052": { "compartment": "compartment_7660", "id": "reaction_10061052", "reactome": "R-BTA-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061119": { "compartment": "compartment_7660", "id": "reaction_10061119", "reactome": "R-BTA-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023940" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10061137": { "compartment": "compartment_7660", "id": "reaction_10061137", "reactome": "R-BTA-1855233", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023907" ], "products": [ "species_113582", "species_2023891" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060993": { "compartment": "compartment_7660", "id": "reaction_10060993", "reactome": "R-BTA-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10060990", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10061031": { "compartment": "compartment_7660", "id": "reaction_10061031", "reactome": "R-BTA-1855185", "name": "I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023935" ], "products": [ "species_113582", "species_2023901" ], "modifiers": [ [ "species_10061028", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014872" ] }, "reaction_10060951": { "compartment": "compartment_7660", "id": "reaction_10060951", "reactome": "R-BTA-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10060948", "catalyst" ] ], "additional_components": [ "Q0II95", "ENSBTAT00000015405", "F6Q4Q6", "ENSBTAT00000030644" ] }, "reaction_10067955": { "compartment": "compartment_70101", "id": "reaction_10067955", "reactome": "R-BTA-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067950" ], "products": [ "species_29372", "species_10067952" ], "modifiers": [ [ "species_10067950", "catalyst" ], [ "species_10067948", "catalyst" ] ], "additional_components": [ "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_29370", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890" ] }, "reaction_10068022": { "compartment": "compartment_70101", "id": "reaction_10068022", "reactome": "R-BTA-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068020", "species_10068018" ], "products": [ "species_10067950" ], "modifiers": [], "additional_components": [ "species_113592", "Q27975", "ENSBTAT00000017500", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "F1N6Q0", "ENSBTAT00000021199", "Q5E954", "ENSBTAT00000021637", "Q2HJ94", "ENSBTAT00000004890", "species_113592", "Q27975", "ENSBTAT00000017500" ] }, "reaction_10065708": { "compartment": "compartment_70101", "id": "reaction_10065708", "reactome": "R-BTA-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697" ], "products": [ "species_10065705" ], "modifiers": [ [ "species_10065697", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011761", "F1MW01", "ENSBTAT00000011761", "ENSBTAT00000011761" ] }, "reaction_10065726": { "compartment": "compartment_70101", "id": "reaction_10065726", "reactome": "R-BTA-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065697", "species_10065722" ], "products": [ "species_10065724" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011761", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "G3N089", "ENSBTAT00000066220", "A0A452DIH5", "ENSBTAT00000066220", "G3MYU8", "ENSBTAT00000066220", "F1MW01", "ENSBTAT00000011761" ] }, "reaction_10091145": { "compartment": "compartment_70101", "id": "reaction_10091145", "reactome": "R-BTA-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10091134" ], "products": [ "species_10091143" ], "modifiers": [], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438" ] }, "reaction_10091141": { "compartment": "compartment_1598585", "id": "reaction_10091141", "reactome": "R-BTA-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10043519" ], "products": [ "species_29420", "species_10091134" ], "modifiers": [ [ "species_10091138", "catalyst" ] ], "additional_components": [ "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29420", "G3MZP2", "ENSBTAT00000033457", "G5E619", "ENSBTAT00000033457", "species_29438", "ENSBTAT00000066656" ] }, "reaction_10091132": { "compartment": "compartment_13231", "id": "reaction_10091132", "reactome": "R-BTA-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10091128" ], "products": [ "species_10091130" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "ENSBTAT00000011125", "A6QQV8", "ENSBTAT00000011125", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10091656": { "compartment": "compartment_70101", "id": "reaction_10091656", "reactome": "R-BTA-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091652", "species_10091648" ], "products": [ "species_10091654" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065503", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "G3X8E2", "ENSBTAT00000065503" ] }, "reaction_10091658": { "compartment": "compartment_13231", "id": "reaction_10091658", "reactome": "R-BTA-9668395", "name": "CHMP7 binds CC2D1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091644", "species_10091640" ], "products": [ "species_10091646" ], "modifiers": [], "additional_components": [ "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000021129", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091661": { "compartment": "compartment_70101", "id": "reaction_10091661", "reactome": "R-BTA-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_29356", "species_113592" ], "products": [ "species_29372", "species_10040834", "species_29370" ], "modifiers": [ [ "species_10091648", "catalyst" ] ], "additional_components": [ "species_29438", "species_29420", "species_29438", "species_29420", "F1N7R5", "ENSBTAT00000021129", "E1B828", "ENSBTAT00000020642", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091634": { "compartment": "compartment_70101", "id": "reaction_10091634", "reactome": "R-BTA-9668335", "name": "CHMP7 binds LEMD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052771", "species_10070769" ], "products": [ "species_10091632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017987", "ENSBTAT00000020642", "E1B828", "ENSBTAT00000020642", "A6H704", "ENSBTAT00000017987" ] }, "reaction_10091663": { "compartment": "compartment_7660", "id": "reaction_10091663", "reactome": "R-BTA-9668904", "name": "Formation of the CTF18 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039904", "species_10039900", "species_10039896" ], "products": [ "species_10039906" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020389", "ENSBTAT00000002226", "ENSBTAT00000026311", "E1B8Q4", "ENSBTAT00000026311", "P0CG11", "ENSBTAT00000002226", "F1MTU0", "ENSBTAT00000020389" ] }, "reaction_10057418": { "compartment": "compartment_876", "id": "reaction_10057418", "reactome": "R-BTA-1296046", "name": "KCNJs transport K+ from the extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10057415", "catalyst" ] ], "additional_components": [ "O19182", "ENSBTAT00000010914", "A0A3Q1M4V6", "ENSBTAT00000078632", "E1BCI4", "ENSBTAT00000000089" ] }, "reaction_10064591": { "compartment": "compartment_70616", "id": "reaction_10064591", "reactome": "R-BTA-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10064588", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007549" ] }, "reaction_10046968": { "compartment": "compartment_70101", "id": "reaction_10046968", "reactome": "R-BTA-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389545", "species_29366" ], "products": [ "species_29406", "species_70106", "species_113528", "species_29364" ], "modifiers": [ [ "species_10046965", "catalyst" ] ], "additional_components": [ "A0A140T8A5", "ENSBTAT00000027348" ] }, "reaction_10058524": { "compartment": "compartment_70101", "id": "reaction_10058524", "reactome": "R-BTA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1474124" ], "products": [ "species_1475054", "species_1474179" ], "modifiers": [ [ "species_10058521", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411" ] }, "reaction_10058511": { "compartment": "compartment_70101", "id": "reaction_10058511", "reactome": "R-BTA-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10058500", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ], [ "species_10058509", "inhibitor" ] ], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10058785": { "compartment": "compartment_70101", "id": "reaction_10058785", "reactome": "R-BTA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10058778" ], "products": [ "species_29370", "species_10058521" ], "modifiers": [ [ "species_10058782", "catalyst" ] ], "additional_components": [ "A0A3Q1MA59", "ENSBTAT00000030411", "species_29426", "A0A3Q1MA59", "ENSBTAT00000030411", "ENSBTAT00000003877" ] }, "reaction_10058514": { "compartment": "compartment_70101", "id": "reaction_10058514", "reactome": "R-BTA-1474158", "name": "GCHFR binds to GCH1 and negatively regulates its activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058500", "species_10058507" ], "products": [ "species_10058509" ], "modifiers": [], "additional_components": [ "F1MZ14", "ENSBTAT00000009020", "Q32L41", "ENSBTAT00000017922", "Q32L41", "ENSBTAT00000017922", "F1MZ14", "ENSBTAT00000009020" ] }, "reaction_10085853": { "compartment": "compartment_70101", "id": "reaction_10085853", "reactome": "R-BTA-8874705", "name": "TTPA transports alpha-TOH from lysosomal membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085849" ], "products": [ "species_10085851" ], "modifiers": [], "additional_components": [ "species_8874708", "F1N086", "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10085855": { "compartment": "compartment_70101", "id": "reaction_10085855", "reactome": "R-BTA-8874718", "name": "TTPA binds alpha-TOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085847", "species_8874708" ], "products": [ "species_10085849" ], "modifiers": [], "additional_components": [ "ENSBTAT00000030426", "species_8874708", "F1N086", "ENSBTAT00000030426" ] }, "reaction_10081928": { "compartment": "compartment_17957", "id": "reaction_10081928", "reactome": "R-BTA-6806647", "name": "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10081925", "catalyst" ] ], "additional_components": [ "ENSBTAT00000064807" ] }, "reaction_10038427": { "compartment": "compartment_12045", "id": "reaction_10038427", "reactome": "R-BTA-159790", "name": "VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_6806366" ], "products": [ "species_6806362" ], "modifiers": [ [ "species_10038422", "catalyst" ], [ "species_10038425", "inhibitor" ] ], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10090493": { "compartment": "compartment_12045", "id": "reaction_10090493", "reactome": "R-BTA-9026967", "name": "VKORC1 inhibitors binds VKORC1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038422", "species_9035082" ], "products": [ "species_10038425" ], "modifiers": [], "additional_components": [ "Q6B4J2", "ENSBTAT00000000519", "Q6B4J2", "ENSBTAT00000000519" ] }, "reaction_10081935": { "compartment": "compartment_17957", "id": "reaction_10081935", "reactome": "R-BTA-6806674", "name": "UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806891", "species_6806657" ], "products": [ "species_6806362", "species_6806656" ], "modifiers": [ [ "species_10081932", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018617" ] }, "reaction_10054393": { "compartment": "compartment_70101", "id": "reaction_10054393", "reactome": "R-BTA-975629", "name": "RDH11 reduces RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10035574", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "ENSBTAT00000002535" ] }, "reaction_10066249": { "compartment": "compartment_70101", "id": "reaction_10066249", "reactome": "R-BTA-2855259", "name": "atROL binds RBP1 (parenchymal cell)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473610", "species_10035554" ], "products": [ "species_10065443" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590" ] }, "reaction_10054395": { "compartment": "compartment_70101", "id": "reaction_10054395", "reactome": "R-BTA-975633", "name": "atROL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975590" ], "products": [ "species_10054388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10070971": { "compartment": "compartment_984", "id": "reaction_10070971", "reactome": "R-BTA-5246478", "name": "APOM binds retinoids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070967", "species_5246487" ], "products": [ "species_10070969" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075540", "species_975590", "species_5362520", "species_215573", "species_975590", "species_5362520", "species_215573", "A0A3Q1MB70", "ENSBTAT00000075540" ] }, "reaction_10065437": { "compartment": "compartment_70101", "id": "reaction_10065437", "reactome": "R-BTA-2399913", "name": "atRAL binds to RBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054386", "species_975622" ], "products": [ "species_10054390" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078995", "species_975622", "A7MBG1", "ENSBTAT00000078995" ] }, "reaction_10069948": { "compartment": "compartment_5460", "id": "reaction_10069948", "reactome": "R-BTA-5164399", "name": "BCO2:Fe2+ cleaves betaC to APO10al and bION", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_5164389" ], "products": [ "species_5164390", "species_5164383" ], "modifiers": [ [ "species_10069945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N2Z9", "ENSBTAT00000048395" ] }, "reaction_10054382": { "compartment": "compartment_984", "id": "reaction_10054382", "reactome": "R-BTA-975594", "name": "PLB1 hydrolyses RPALM to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10065441": { "compartment": "compartment_70101", "id": "reaction_10065441", "reactome": "R-BTA-2404142", "name": "atROL binds RBP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473616" ], "products": [ "species_10065439" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065445": { "compartment": "compartment_70101", "id": "reaction_10065445", "reactome": "R-BTA-2404144", "name": "Parenchymal atROL translocates to HSCs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065443" ], "products": [ "species_10035554", "species_2473616" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10054404": { "compartment": "compartment_70101", "id": "reaction_10054404", "reactome": "R-BTA-975635", "name": "BCMO1:Fe2+ cleaves betaC to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_975643" ], "products": [ "species_975622" ], "modifiers": [ [ "species_10054401", "catalyst" ] ], "additional_components": [ "F1N3B7", "ENSBTAT00000048748", "species_71067" ] }, "reaction_10054375": { "compartment": "compartment_984", "id": "reaction_10054375", "reactome": "R-BTA-975593", "name": "PNLIP:CLPS hydrolyses RPALM to atROL and PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_975591" ], "products": [ "species_975590", "species_426576" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10066247": { "compartment": "compartment_70101", "id": "reaction_10066247", "reactome": "R-BTA-2855252", "name": "AKRs reduce RBP2:atRAL to RBP2:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054390", "species_70106", "species_29364" ], "products": [ "species_10054388", "species_29366" ], "modifiers": [ [ "species_10066244", "catalyst" ] ], "additional_components": [ "species_975622", "A7MBG1", "ENSBTAT00000078995", "species_975590", "A7MBG1", "ENSBTAT00000078995", "E1BP71", "ENSBTAT00000039350", "M0QW21", "ENSBTAT00000028488", "E1BG58", "ENSBTAT00000038997", "M0QW25", "ENSBTAT00000030566", "M0QW04", "ENSBTAT00000038997", "M0QW14", "ENSBTAT00000023326", "F1MT58", "ENSBTAT00000055749", "Q3ZBG2", "ENSBTAT00000023297", "G3X704", "ENSBTAT00000023326", "F1MK69", "ENSBTAT00000056823", "P52897", "ENSBTAT00000024086", "F1MNC0", "ENSBTAT00000039362", "P52898", "ENSBTAT00000024086", "F1N678", "ENSBTAT00000002073" ] }, "reaction_10042657": { "compartment": "compartment_876", "id": "reaction_10042657", "reactome": "R-BTA-199219", "name": "SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199238", "species_74113" ], "products": [ "species_83910", "species_199207" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10066401": { "compartment": "compartment_70101", "id": "reaction_10066401", "reactome": "R-BTA-2993447", "name": "HLCS biotinylates 6x(PCCA:PCCB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066388", "species_113592", "species_199207" ], "products": [ "species_111294", "species_10066394", "species_76577" ], "modifiers": [ [ "species_10066398", "catalyst" ] ], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "ENSBTAT00000057284" ] }, "reaction_10067733": { "compartment": "compartment_70101", "id": "reaction_10067733", "reactome": "R-BTA-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066394" ], "products": [ "species_10033909" ], "modifiers": [], "additional_components": [ "A0A452DIR0", "ENSBTAT00000020252", "A0A3Q1N969", "ENSBTAT00000086761", "A0A3Q1N969", "ENSBTAT00000086761", "A0A452DIR0", "ENSBTAT00000020252" ] }, "reaction_10042936": { "compartment": "compartment_70616", "id": "reaction_10042936", "reactome": "R-BTA-200680", "name": "SLC25A32 transports THF from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355" ], "products": [ "species_200671" ], "modifiers": [ [ "species_10042933", "catalyst" ] ], "additional_components": [ "ENSBTAT00000048106" ] }, "reaction_10081339": { "compartment": "compartment_5460", "id": "reaction_10081339", "reactome": "R-BTA-6801328", "name": "MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_5693984" ], "products": [ "species_6801458", "species_29362" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10042940": { "compartment": "compartment_876", "id": "reaction_10042940", "reactome": "R-BTA-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10082078": { "compartment": "compartment_70101", "id": "reaction_10082078", "reactome": "R-BTA-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111353", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_197969" ], "modifiers": [ [ "species_10082075", "catalyst" ] ], "additional_components": [ "E1BMG9", "ENSBTAT00000043693" ] }, "reaction_10042929": { "compartment": "compartment_876", "id": "reaction_10042929", "reactome": "R-BTA-200652", "name": "SLC19A1 transports 5-methyl-THF from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200709" ], "products": [ "species_200665" ], "modifiers": [ [ "species_10042926", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082124" ] }, "reaction_10041840": { "compartment": "compartment_70101", "id": "reaction_10041840", "reactome": "R-BTA-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73604", "species_29364" ], "products": [ "species_111355", "species_29366" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10087442": { "compartment": "compartment_984", "id": "reaction_10087442", "reactome": "R-BTA-8942344", "name": "FOLR2 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086761" ], "products": [ "species_197965", "species_10086759" ], "modifiers": [], "additional_components": [ "Q0VCN9", "ENSBTAT00000027602", "species_197965", "ENSBTAT00000027602" ] }, "reaction_10092306": { "compartment": "compartment_70101", "id": "reaction_10092306", "reactome": "R-BTA-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10092303", "catalyst" ] ], "additional_components": [ "A0A140T872", "ENSBTAT00000010103" ] }, "reaction_10082068": { "compartment": "compartment_5460", "id": "reaction_10082068", "reactome": "R-BTA-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_6808499", "species_113521" ], "products": [ "species_113529", "species_200679", "species_113600", "species_29376" ], "modifiers": [ [ "species_10082065", "catalyst" ] ], "additional_components": [ "E1BDG9", "ENSBTAT00000008298" ] }, "reaction_10086763": { "compartment": "compartment_984", "id": "reaction_10086763", "reactome": "R-BTA-8940134", "name": "FOLR2 binds FOLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716", "species_10086759" ], "products": [ "species_10086761" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027602", "Q0VCN9", "ENSBTAT00000027602", "species_197965" ] }, "reaction_10042922": { "compartment": "compartment_876", "id": "reaction_10042922", "reactome": "R-BTA-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035283" ] }, "reaction_10041838": { "compartment": "compartment_70101", "id": "reaction_10041838", "reactome": "R-BTA-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965", "species_70106", "species_29364" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10041835", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010103" ] }, "reaction_10081346": { "compartment": "compartment_70101", "id": "reaction_10081346", "reactome": "R-BTA-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_29372", "species_70106", "species_29370", "species_200640" ], "modifiers": [ [ "species_10081343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026669" ] }, "reaction_10076485": { "compartment": "compartment_70616", "id": "reaction_10076485", "reactome": "R-BTA-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_5693984", "species_113521" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10076482", "catalyst" ] ], "additional_components": [ "Q3SZ20", "ENSBTAT00000038244" ] }, "reaction_10081349": { "compartment": "compartment_5460", "id": "reaction_10081349", "reactome": "R-BTA-6801462", "name": "MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6801458", "species_113521" ], "products": [ "species_5389850" ], "modifiers": [ [ "species_10081336", "catalyst" ] ], "additional_components": [ "A0A452DI11", "ENSBTAT00000006419", "E1BNJ2", "ENSBTAT00000061329" ] }, "reaction_10041817": { "compartment": "compartment_70101", "id": "reaction_10041817", "reactome": "R-BTA-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10041814", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1NKT9", "ENSBTAT00000069099" ] }, "reaction_10042906": { "compartment": "compartment_5460", "id": "reaction_10042906", "reactome": "R-BTA-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938078", "species_8938090" ], "modifiers": [ [ "species_10042903", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NCV5", "ENSBTAT00000074137" ] }, "reaction_10088666": { "compartment": "compartment_5460", "id": "reaction_10088666", "reactome": "R-BTA-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_113526" ], "products": [ "species_113581", "species_113563", "species_113529" ], "modifiers": [ [ "species_10088663", "catalyst" ] ], "additional_components": [ "A0A3Q1LR42", "ENSBTAT00000077253" ] }, "reaction_10086748": { "compartment": "compartment_984", "id": "reaction_10086748", "reactome": "R-BTA-8940070", "name": "NT5E:Zn2+ hydrolyses NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_109277", "species_8940067" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10086750": { "compartment": "compartment_984", "id": "reaction_10086750", "reactome": "R-BTA-8940074", "name": "NT5E:Zn2+ hydrolyses NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8940067" ], "products": [ "species_109277", "species_8940077" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10085374": { "compartment": "compartment_984", "id": "reaction_10085374", "reactome": "R-BTA-8870346", "name": "BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10085371", "catalyst" ] ], "additional_components": [ "F1MLP3", "ENSBTAT00000008097" ] }, "reaction_10085362": { "compartment": "compartment_70101", "id": "reaction_10085362", "reactome": "R-BTA-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10085365": { "compartment": "compartment_70101", "id": "reaction_10085365", "reactome": "R-BTA-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_8869353", "species_70106", "species_29370" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10081977": { "compartment": "compartment_5460", "id": "reaction_10081977", "reactome": "R-BTA-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10081974", "catalyst" ] ], "additional_components": [ "A0A3Q1MF13", "ENSBTAT00000080451" ] }, "reaction_10071643": { "compartment": "compartment_70101", "id": "reaction_10071643", "reactome": "R-BTA-5359451", "name": "NNMT transfers CH3 from SAM to NAM to form MNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197277", "species_71284" ], "products": [ "species_549282", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10086623": { "compartment": "compartment_70101", "id": "reaction_10086623", "reactome": "R-BTA-8938073", "name": "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938276", "species_29360" ], "products": [ "species_197277", "species_8938282" ], "modifiers": [ [ "species_10086620", "catalyst" ] ], "additional_components": [ "F6R6Y8", "ENSBTAT00000029045", "A0A3Q1M0E5", "ENSBTAT00000084343", "F1MRP9", "ENSBTAT00000012765" ] }, "reaction_10082143": { "compartment": "compartment_17951", "id": "reaction_10082143", "reactome": "R-BTA-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192305", "species_389620" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10082140", "catalyst" ] ], "additional_components": [ "ENSBTAT00000039965" ] }, "reaction_10041824": { "compartment": "compartment_70101", "id": "reaction_10041824", "reactome": "R-BTA-197250", "name": "NAMPT transfers PRIB to NAM to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197277" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041821", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083136" ] }, "reaction_10041808": { "compartment": "compartment_70101", "id": "reaction_10041808", "reactome": "R-BTA-197186", "name": "NAPRT1 dimer transfers PRIB to NCA to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_197230", "species_70106" ], "products": [ "species_111294", "species_197220" ], "modifiers": [ [ "species_10041805", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "A0A3Q1N5S3", "ENSBTAT00000084634" ] }, "reaction_10081984": { "compartment": "compartment_5460", "id": "reaction_10081984", "reactome": "R-BTA-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6807477" ], "products": [ "species_113548", "species_113581", "species_113529", "species_113600" ], "modifiers": [ [ "species_10081981", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015238" ] }, "reaction_10088867": { "compartment": "compartment_984", "id": "reaction_10088867", "reactome": "R-BTA-8956458", "name": "RNLS:FAD oxidises dh-beta-NAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_352327", "species_8956473" ], "products": [ "species_352330", "species_351629" ], "modifiers": [ [ "species_10088864", "catalyst" ] ], "additional_components": [ "CHEBI:90174", "CHEBI:90171", "A0A3Q1NF84", "ENSBTAT00000069540", "species_113596" ] }, "reaction_10049170": { "compartment": "compartment_876", "id": "reaction_10049170", "reactome": "R-BTA-429749", "name": "SLC5A8 transports monocarboxylates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429739", "species_74113" ], "products": [ "species_83910", "species_429748" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_76179", "species_2022890", "CHEBI:30768", "species_76179", "species_113557", "species_2022890", "species_373863", "CHEBI:30768", "species_197230", "ENSBTAT00000015315" ] }, "reaction_10085352": { "compartment": "compartment_70101", "id": "reaction_10085352", "reactome": "R-BTA-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085349", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072443" ] }, "reaction_10085359": { "compartment": "compartment_70101", "id": "reaction_10085359", "reactome": "R-BTA-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10085356", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044763" ] }, "reaction_10042915": { "compartment": "compartment_7660", "id": "reaction_10042915", "reactome": "R-BTA-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200492", "species_29358" ], "products": [ "species_8878981", "species_200499" ], "modifiers": [ [ "species_10042912", "catalyst" ] ], "additional_components": [ "Q0VD50", "ENSBTAT00000082151", "species_29426" ] }, "reaction_10041831": { "compartment": "compartment_70101", "id": "reaction_10041831", "reactome": "R-BTA-197268", "name": "QPRT transfers PRIB to QUIN to form NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_70106", "species_197238" ], "products": [ "species_111294", "species_113528", "species_197220" ], "modifiers": [ [ "species_10041828", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083204" ] }, "reaction_10086630": { "compartment": "compartment_984", "id": "reaction_10086630", "reactome": "R-BTA-8938076", "name": "CD38 hydrolyses NAD+ to NAM and ADP-ribose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352330", "species_109276" ], "products": [ "species_351626", "species_8870342", "species_8870343" ], "modifiers": [ [ "species_10086627", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073897" ] }, "reaction_10053298": { "compartment": "compartment_70101", "id": "reaction_10053298", "reactome": "R-BTA-947531", "name": "Molybdenum ion transfer onto molybdopterin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947561", "species_947496" ], "products": [ "species_111294", "species_947539", "species_76577" ], "modifiers": [ [ "species_10053295", "catalyst" ] ], "additional_components": [ "A0A3Q1ME13", "ENSBTAT00000081310", "species_29926" ] }, "reaction_10053266": { "compartment": "compartment_70101", "id": "reaction_10053266", "reactome": "R-BTA-947499", "name": "Exchange of oxygen with sulfur in MoCo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947539", "species_111707" ], "products": [ "species_947575", "species_29432" ], "modifiers": [ [ "species_10053263", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065375" ] }, "reaction_10053287": { "compartment": "compartment_70101", "id": "reaction_10053287", "reactome": "R-BTA-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_10053272" ], "products": [ "species_29432", "species_10053277" ], "modifiers": [ [ "species_10053284", "catalyst" ] ], "additional_components": [ "species_29426", "A1A4L8", "ENSBTAT00000070167", "A1A4L8", "ENSBTAT00000070167", "species_29426", "A5PKG4", "ENSBTAT00000009149" ] }, "reaction_10053352": { "compartment": "compartment_70101", "id": "reaction_10053352", "reactome": "R-BTA-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965131" ], "products": [ "species_29390", "species_29370" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10066619": { "compartment": "compartment_70101", "id": "reaction_10066619", "reactome": "R-BTA-3204311", "name": "AOX1 oxidises PXL to PDXate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965131" ], "products": [ "species_3204324", "species_29408" ], "modifiers": [ [ "species_10066616", "catalyst" ] ], "additional_components": [ "CHEBI:33722", "CHEBI:44074", "species_113596", "A0A3Q1LJG6", "ENSBTAT00000075745" ] }, "reaction_10053361": { "compartment": "compartment_70101", "id": "reaction_10053361", "reactome": "R-BTA-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_964952" ], "products": [ "species_29390", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053363": { "compartment": "compartment_70101", "id": "reaction_10053363", "reactome": "R-BTA-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29368", "species_965146" ], "products": [ "species_29390", "species_31633", "species_29408" ], "modifiers": [ [ "species_10053358", "catalyst" ] ], "additional_components": [ "Q5E9K3", "ENSBTAT00000016263", "species_73524" ] }, "reaction_10053348": { "compartment": "compartment_70101", "id": "reaction_10053348", "reactome": "R-BTA-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10053350": { "compartment": "compartment_70101", "id": "reaction_10053350", "reactome": "R-BTA-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_965053" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10053345", "catalyst" ] ], "additional_components": [ "species_29426", "Q0II59", "ENSBTAT00000024203" ] }, "reaction_10041753": { "compartment": "compartment_70101", "id": "reaction_10041753", "reactome": "R-BTA-196761", "name": "2xTPK1:Mg2+ phosphorylates THMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196934" ], "products": [ "species_29480", "species_76577" ], "modifiers": [ [ "species_10041750", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LMH4", "ENSBTAT00000085465" ] }, "reaction_10042799": { "compartment": "compartment_876", "id": "reaction_10042799", "reactome": "R-BTA-199626", "name": "SLC19A2/3 transport extracellular THMN to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199622" ], "products": [ "species_196934" ], "modifiers": [ [ "species_10042796", "catalyst" ] ], "additional_components": [ "A7E352", "ENSBTAT00000084175", "E1BLU2", "ENSBTAT00000027006" ] }, "reaction_10066585": { "compartment": "compartment_5460", "id": "reaction_10066585", "reactome": "R-BTA-3159253", "name": "MMAB transfers adenosyl group from ATP to cob(I)alamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3159260", "species_113593" ], "products": [ "species_3159274", "species_3159297" ], "modifiers": [ [ "species_10066582", "catalyst" ] ], "additional_components": [ "A0A3Q1NBS4", "ENSBTAT00000056628" ] }, "reaction_10066587": { "compartment": "compartment_5460", "id": "reaction_10066587", "reactome": "R-BTA-3159259", "name": "MMAA:MUT binds AdoCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033882", "species_3159297" ], "products": [ "species_10033884" ], "modifiers": [], "additional_components": [ "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806", "species_3159297", "Q0III1", "ENSBTAT00000076678", "A6QQI8", "ENSBTAT00000029806" ] }, "reaction_10066458": { "compartment": "compartment_984", "id": "reaction_10066458", "reactome": "R-BTA-3000120", "name": "GIF binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066454", "species_3000125" ], "products": [ "species_10066456" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066461": { "compartment": "compartment_984", "id": "reaction_10066461", "reactome": "R-BTA-3000122", "name": "CD320 transports extracellular TCII:Cbl to endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066428", "species_10066440" ], "products": [ "species_10066438" ], "modifiers": [ [ "species_10066440", "catalyst" ] ], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777", "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10076254": { "compartment": "compartment_984", "id": "reaction_10076254", "reactome": "R-BTA-5693319", "name": "CTRC hydrolyses PRSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10076243" ], "products": [ "species_10076247", "species_10076245" ], "modifiers": [ [ "species_10076251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000028731", "ENSBTAT00000071882" ] }, "reaction_10066526": { "compartment": "compartment_984", "id": "reaction_10066526", "reactome": "R-BTA-3132753", "name": "Pancreatic proteases degrade TCN1:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066519" ], "products": [ "species_3000125" ], "modifiers": [ [ "species_10066523", "catalyst" ] ], "additional_components": [ "species_3000241", "E1BCU6", "ENSBTAT00000027423", "A7YWU6", "ENSBTAT00000053990", "A7YWU9", "ENSBTAT00000028731", "A5PJB8", "ENSBTAT00000053990", "A0A3Q1LWD8", "ENSBTAT00000076474" ] }, "reaction_10066430": { "compartment": "compartment_984", "id": "reaction_10066430", "reactome": "R-BTA-3000074", "name": "TCII binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066426", "species_3000125" ], "products": [ "species_10066428" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066576": { "compartment": "compartment_70101", "id": "reaction_10066576", "reactome": "R-BTA-3149563", "name": "MMADHC targets transport of cytosolic cob(II)alamin to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149564" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066450": { "compartment": "compartment_17940", "id": "reaction_10066450", "reactome": "R-BTA-3000112", "name": "Endosomal TCII:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066442" ], "products": [ "species_10066448" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066569": { "compartment": "compartment_70101", "id": "reaction_10066569", "reactome": "R-BTA-3149492", "name": "cob(II)alamin dissociates from MMACHC:MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066565" ], "products": [ "species_10066567", "species_3149479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246" ] }, "reaction_10066473": { "compartment": "compartment_161320", "id": "reaction_10066473", "reactome": "R-BTA-3000263", "name": "TCII:Cbl is degraded to release Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066448" ], "products": [ "species_3000239" ], "modifiers": [], "additional_components": [ "species_3000241", "Q9XSC9", "ENSBTAT00000029446" ] }, "reaction_10066571": { "compartment": "compartment_70101", "id": "reaction_10066571", "reactome": "R-BTA-3149494", "name": "MMACHC:cob(II)alamin binds MMADHC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066563", "species_10066499" ], "products": [ "species_10066565" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "A0A3Q1M6Z9", "ENSBTAT00000087246", "species_3149479", "Q5E9C8", "ENSBTAT00000022638" ] }, "reaction_10066444": { "compartment": "compartment_74700", "id": "reaction_10066444", "reactome": "R-BTA-3000109", "name": "CD320:TCII:Cbl dissociates into CD320 and TCII:Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066438" ], "products": [ "species_10066442", "species_10066440" ], "modifiers": [], "additional_components": [ "species_3000241", "A6QNY1", "ENSBTAT00000005777", "Q9XSC9", "ENSBTAT00000029446", "species_3000241", "Q9XSC9", "ENSBTAT00000029446", "ENSBTAT00000005777" ] }, "reaction_10066574": { "compartment": "compartment_70101", "id": "reaction_10066574", "reactome": "R-BTA-3149519", "name": "MMACHC decyanates CNCbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_10066497", "species_29364", "species_3149505" ], "products": [ "species_10066499", "species_29366", "species_1130611" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10066528": { "compartment": "compartment_984", "id": "reaction_10066528", "reactome": "R-BTA-3132759", "name": "TCN1 binds Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3132775" ], "products": [ "species_10066519", "species_3132772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066882": { "compartment": "compartment_984", "id": "reaction_10066882", "reactome": "R-BTA-3245898", "name": "TCN1 binds Cbl in the circulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066517", "species_3000125" ], "products": [ "species_10066519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027423", "species_3000241", "E1BCU6", "ENSBTAT00000027423" ] }, "reaction_10066471": { "compartment": "compartment_17940", "id": "reaction_10066471", "reactome": "R-BTA-3000247", "name": "Endosomal GIF:Cbl translocates to lysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066469" ], "products": [ "species_10066465" ], "modifiers": [], "additional_components": [ "species_3000241", "E1BCN2", "ENSBTAT00000015993", "species_3000241", "E1BCN2", "ENSBTAT00000015993" ] }, "reaction_10066502": { "compartment": "compartment_70101", "id": "reaction_10066502", "reactome": "R-BTA-3095889", "name": "MMACHC reduces Cbl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3000241", "species_70106", "species_10066497", "species_29364" ], "products": [ "species_10066499", "species_29366" ], "modifiers": [ [ "species_10066497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022638", "species_3149479", "Q5E9C8", "ENSBTAT00000022638", "ENSBTAT00000022638" ] }, "reaction_10042648": { "compartment": "compartment_876", "id": "reaction_10042648", "reactome": "R-BTA-199206", "name": "SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199192", "species_74113" ], "products": [ "species_83910", "species_196820" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10041737": { "compartment": "compartment_70101", "id": "reaction_10041737", "reactome": "R-BTA-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_113592", "species_196786" ], "products": [ "species_111294", "species_196834", "species_76577" ], "modifiers": [ [ "species_10041734", "catalyst" ] ], "additional_components": [ "A0A3S5ZP75", "ENSBTAT00000017259" ] }, "reaction_10041756": { "compartment": "compartment_70101", "id": "reaction_10041756", "reactome": "R-BTA-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_29370", "species_76194" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10042655": { "compartment": "compartment_70616", "id": "reaction_10042655", "reactome": "R-BTA-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10042652", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031344" ] }, "reaction_10041744": { "compartment": "compartment_70101", "id": "reaction_10041744", "reactome": "R-BTA-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_111294", "species_196778" ], "modifiers": [ [ "species_10041741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072656" ] }, "reaction_10041765": { "compartment": "compartment_70101", "id": "reaction_10041765", "reactome": "R-BTA-196840", "name": "3xPPCDC:3FMN decarboxylates PPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196834" ], "products": [ "species_196767", "species_113528" ], "modifiers": [ [ "species_10041762", "catalyst" ] ], "additional_components": [ "species_73524", "A0A3Q1MNK4", "ENSBTAT00000076608" ] }, "reaction_10053048": { "compartment": "compartment_70101", "id": "reaction_10053048", "reactome": "R-BTA-933533", "name": "Dimerization of p-IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039550" ], "products": [ "species_10039554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053046": { "compartment": "compartment_13231", "id": "reaction_10053046", "reactome": "R-BTA-933531", "name": "Translocation of p-IRF7:p-IRF7 to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10037203": { "compartment": "compartment_7660", "id": "reaction_10037203", "reactome": "R-BTA-113402", "name": "Formation of DSIF:NELF:early elongation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037126", "species_10037171", "species_30595" ], "products": [ "species_10037173", "species_30595" ], "modifiers": [], "additional_components": [ "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "species_110614", "species_113592", "species_29494", "species_29438", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "species_110614", "species_113592", "species_29494", "species_29438" ] }, "reaction_10037205": { "compartment": "compartment_7660", "id": "reaction_10037205", "reactome": "R-BTA-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037169", "species_10037137" ], "products": [ "species_10037171" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412" ] }, "reaction_10086136": { "compartment": "compartment_13946", "id": "reaction_10086136", "reactome": "R-BTA-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086105" ], "products": [ "species_29420", "species_10086115", "species_10085883" ], "modifiers": [ [ "species_10086133", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1N147", "ENSBTAT00000070415", "species_29420", "A0A3Q1N147", "ENSBTAT00000070415", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3T086", "ENSBTAT00000009288", "A0A3Q1MRB3", "ENSBTAT00000079685", "Q17QI1", "ENSBTAT00000065281", "Q32L78", "ENSBTAT00000019999", "Q2TBL9", "ENSBTAT00000010619", "A0A3Q1M4U3", "ENSBTAT00000087207", "F1MSD6", "ENSBTAT00000005590", "Q3T0F2", "ENSBTAT00000014509", "A0A3Q1N5L8", "ENSBTAT00000086931", "A0A3Q1MK52", "ENSBTAT00000082010", "F1MXL8", "ENSBTAT00000009769" ] }, "reaction_10085932": { "compartment": "compartment_437051", "id": "reaction_10085932", "reactome": "R-BTA-8876188", "name": "DENND4s exchange GTP for GDP on RAB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085911", "species_29438" ], "products": [ "species_29420", "species_10085915", "species_10085883" ], "modifiers": [ [ "species_10085929", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QLS9", "ENSBTAT00000001303", "species_29420", "A6QLS9", "ENSBTAT00000001303", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BJE1", "ENSBTAT00000022733", "F1N377", "ENSBTAT00000034026", "A0A3Q1NBE4", "ENSBTAT00000073212" ] }, "reaction_10086097": { "compartment": "compartment_171062", "id": "reaction_10086097", "reactome": "R-BTA-8877311", "name": "RAB31 GEFs exchange GTP for GDP on RAB31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086086", "species_29438" ], "products": [ "species_29420", "species_10086090", "species_10085883" ], "modifiers": [ [ "species_10086094", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29420", "Q08DC2", "ENSBTAT00000075871", "Q08DC2", "ENSBTAT00000075871", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000013748" ] }, "reaction_10086209": { "compartment": "compartment_20699", "id": "reaction_10086209", "reactome": "R-BTA-8877813", "name": "DENND5A,B exchange GTP for GDP on RAB39", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086188" ], "products": [ "species_10086196", "species_29420", "species_10085883" ], "modifiers": [ [ "species_10086206", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "G3X7D3", "ENSBTAT00000024288", "species_29420", "G3X7D3", "ENSBTAT00000024288", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MUN3", "ENSBTAT00000069720", "F1MQ87", "ENSBTAT00000027075" ] }, "reaction_10086019": { "compartment": "compartment_70101", "id": "reaction_10086019", "reactome": "R-BTA-8876616", "name": "DENND6A,B exchange GTP for GDP on RAB14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086008" ], "products": [ "species_29420", "species_10086012", "species_10085883" ], "modifiers": [ [ "species_10086016", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "Q3ZBG1", "ENSBTAT00000023671", "species_29420", "Q3ZBG1", "ENSBTAT00000023671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "ENSBTAT00000067401" ] }, "reaction_10085988": { "compartment": "compartment_262783", "id": "reaction_10085988", "reactome": "R-BTA-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10085979" ], "products": [ "species_29420", "species_10085983", "species_10085883" ], "modifiers": [ [ "species_10085985", "catalyst" ] ], "additional_components": [ "species_29420", "A6QPX8", "ENSBTAT00000013671", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A6QPX8", "ENSBTAT00000013671", "species_29438", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "A0A3Q1MCL3", "ENSBTAT00000087265" ] }, "reaction_10086054": { "compartment": "compartment_171062", "id": "reaction_10086054", "reactome": "R-BTA-8876837", "name": "RAB21 GEFs exchange GTP for GDP on RAB21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086037" ], "products": [ "species_29420", "species_10085883", "species_10086041" ], "modifiers": [ [ "species_10086051", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "F1MPP1", "ENSBTAT00000025807", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "species_29438", "F1MPP1", "ENSBTAT00000025807", "A0A3Q1M4Y7", "ENSBTAT00000075635", "A0A3Q1M373", "ENSBTAT00000078087" ] }, "reaction_10086182": { "compartment": "compartment_5668575", "id": "reaction_10086182", "reactome": "R-BTA-8877760", "name": "HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10086161" ], "products": [ "species_29420", "species_10085883", "species_10086169" ], "modifiers": [ [ "species_10086179", "catalyst" ] ], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29420", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1N2I0", "ENSBTAT00000014310", "P21856", "ENSBTAT00000016093", "F1MS24", "ENSBTAT00000012631", "E1BA60", "ENSBTAT00000012905", "E1B9C0", "ENSBTAT00000020971", "species_29438", "E1B7M9", "ENSBTAT00000056415", "A0A3Q1N720", "ENSBTAT00000071404" ] }, "reaction_10048567": { "compartment": "compartment_876", "id": "reaction_10048567", "reactome": "R-BTA-425994", "name": "Na+/H+ exchanger transport (at cell membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10048564", "catalyst" ] ], "additional_components": [ "E1BB11", "ENSBTAT00000002235", "F1MU00", "ENSBTAT00000006073", "E1B8Y0", "ENSBTAT00000054801" ] }, "reaction_10048550": { "compartment": "compartment_171062", "id": "reaction_10048550", "reactome": "R-BTA-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10048547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073706" ] }, "reaction_10058841": { "compartment": "compartment_12045", "id": "reaction_10058841", "reactome": "R-BTA-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10059000": { "compartment": "compartment_12045", "id": "reaction_10059000", "reactome": "R-BTA-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10059851": { "compartment": "compartment_984", "id": "reaction_10059851", "reactome": "R-BTA-1602377", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_426658" ], "products": [ "species_1602420", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058874": { "compartment": "compartment_12045", "id": "reaction_10058874", "reactome": "R-BTA-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_426639", "species_76194" ], "modifiers": [ [ "species_10058838", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068283" ] }, "reaction_10058975": { "compartment": "compartment_12045", "id": "reaction_10058975", "reactome": "R-BTA-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10058972", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059026": { "compartment": "compartment_12045", "id": "reaction_10059026", "reactome": "R-BTA-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426639" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10059023", "catalyst" ] ], "additional_components": [ "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576" ] }, "reaction_10048682": { "compartment": "compartment_7660", "id": "reaction_10048682", "reactome": "R-BTA-427337", "name": "MBD2 binds methylcytosine in chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035250", "species_10035235" ], "products": [ "species_10035252" ], "modifiers": [], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000053498", "G5E683", "ENSBTAT00000053498", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10048717": { "compartment": "compartment_7660", "id": "reaction_10048717", "reactome": "R-BTA-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048700", "species_427523" ], "products": [ "species_427497", "species_10044309", "species_427498" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10048720": { "compartment": "compartment_7660", "id": "reaction_10048720", "reactome": "R-BTA-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044309" ], "products": [ "species_77502", "species_10048712" ], "modifiers": [ [ "species_10048714", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BJI1", "ENSBTAT00000039795", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10044361": { "compartment": "compartment_7660", "id": "reaction_10044361", "reactome": "R-BTA-212252", "name": "Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044357", "species_10044309" ], "products": [ "species_10044359" ], "modifiers": [], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044381": { "compartment": "compartment_7660", "id": "reaction_10044381", "reactome": "R-BTA-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044359" ], "products": [ "species_77502", "species_10044378" ], "modifiers": [ [ "species_10044359", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LPJ7", "ENSBTAT00000083404", "F1N6Y2", "ENSBTAT00000022557" ] }, "reaction_10044333": { "compartment": "compartment_7660", "id": "reaction_10044333", "reactome": "R-BTA-212222", "name": "PRC2 recruits DNA methyltransferases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044307", "species_10044329" ], "products": [ "species_10044331" ], "modifiers": [], "additional_components": [ "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10044390": { "compartment": "compartment_7660", "id": "reaction_10044390", "reactome": "R-BTA-212269", "name": "DNMT1,3A,3B:PRC2 methylates cytosine and histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10044331" ], "products": [ "species_77502", "species_10044387" ], "modifiers": [ [ "species_10044331", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LVT5", "ENSBTAT00000069734", "A0A452DII9", "ENSBTAT00000003549" ] }, "reaction_10070700": { "compartment": "compartment_7660", "id": "reaction_10070700", "reactome": "R-BTA-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10036698" ], "products": [ "species_10036706", "species_5221065" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10070702": { "compartment": "compartment_7660", "id": "reaction_10070702", "reactome": "R-BTA-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10036698" ], "products": [ "species_10036706", "species_5221064" ], "modifiers": [ [ "species_10036698", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "ENSBTAT00000072242" ] }, "reaction_10071065": { "compartment": "compartment_7660", "id": "reaction_10071065", "reactome": "R-BTA-5250938", "name": "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10035231" ], "products": [ "species_2485002", "species_10071014" ], "modifiers": [ [ "species_10071062", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "E1BP59", "ENSBTAT00000061193", "Q1RMP0", "ENSBTAT00000045075", "Q32P78", "ENSBTAT00000043971", "Q3SZ29", "ENSBTAT00000016250", "A7YWA1", "ENSBTAT00000047621", "E1BIX2", "ENSBTAT00000008496", "Q3ZBC0", "ENSBTAT00000030510", "F6QVL1", "ENSBTAT00000032261", "A6QLS0", "ENSBTAT00000018830", "Q32L22", "ENSBTAT00000025246", "F2Z4H3", "ENSBTAT00000000606", "A5PJQ1", "ENSBTAT00000017097", "E1B6X6", "ENSBTAT00000072070", "E1BKX3", "ENSBTAT00000009771", "F1MX61", "ENSBTAT00000011734", "A0A3Q1M384", "ENSBTAT00000070441", "F6QHI8", "ENSBTAT00000019351", "Q1JQD6", "ENSBTAT00000043676", "Q32LB6", "ENSBTAT00000004611", "F1MUD5", "ENSBTAT00000056158" ] }, "reaction_10065336": { "compartment": "compartment_984", "id": "reaction_10065336", "reactome": "R-BTA-2395328", "name": "LTBP1, LTBP3 bind TGF-Beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065332", "species_10065308" ], "products": [ "species_10065334" ], "modifiers": [], "additional_components": [ "A6QP91", "ENSBTAT00000015925", "ENSBTAT00000075583", "A0A3Q1LJU9", "ENSBTAT00000075583", "A6QP91", "ENSBTAT00000015925" ] }, "reaction_10065435": { "compartment": "compartment_984", "id": "reaction_10065435", "reactome": "R-BTA-2396399", "name": "Fibrillins bind BMPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065431", "species_10063837" ], "products": [ "species_10065433" ], "modifiers": [], "additional_components": [ "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807", "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360", "Q2KJH1", "ENSBTAT00000004992", "F1MLT0", "ENSBTAT00000060945", "E1B8X7", "ENSBTAT00000001312", "F1MT44", "ENSBTAT00000005807" ] }, "reaction_10064435": { "compartment": "compartment_984", "id": "reaction_10064435", "reactome": "R-BTA-2161282", "name": "Elastic fibres bind associated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064421", "species_10064431" ], "products": [ "species_10064433" ], "modifiers": [], "additional_components": [ "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "P55918", "ENSBTAT00000008130", "Q5EA98", "ENSBTAT00000022877", "A0A3Q1MEV3", "ENSBTAT00000068399", "F1MTZ4", "ENSBTAT00000020360", "A0A3Q1MN12", "ENSBTAT00000070645", "E1BLS8", "ENSBTAT00000015049" ] }, "reaction_10063839": { "compartment": "compartment_984", "id": "reaction_10063839", "reactome": "R-BTA-2129362", "name": "Fibrillin microfibril assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063825" ], "products": [ "species_10063837" ], "modifiers": [], "additional_components": [ "F1MTZ4", "ENSBTAT00000020360", "F1MTZ4", "ENSBTAT00000020360" ] }, "reaction_10064437": { "compartment": "compartment_984", "id": "reaction_10064437", "reactome": "R-BTA-2161293", "name": "Tropoelastin forms aggregate globules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059655" ], "products": [ "species_10063809" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068399", "A0A3Q1MEV3", "ENSBTAT00000068399" ] }, "reaction_10067346": { "compartment": "compartment_70101", "id": "reaction_10067346", "reactome": "R-BTA-3295580", "name": "TRPM4,5 transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10067343", "catalyst" ] ], "additional_components": [ "E1BNX9", "ENSBTAT00000008077", "A0A3Q1M0Y5", "ENSBTAT00000075032" ] }, "reaction_10092050": { "compartment": "compartment_70101", "id": "reaction_10092050", "reactome": "R-BTA-9701055", "name": "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10092047", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G5E522", "ENSBTAT00000002668", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10067332": { "compartment": "compartment_70101", "id": "reaction_10067332", "reactome": "R-BTA-3295579", "name": "TRPs transport extracellular Ca2+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10067306", "catalyst" ], [ "species_10067330", "catalyst" ] ], "additional_components": [ "G3MY82", "ENSBTAT00000065500", "E1BPC8", "ENSBTAT00000019509", "G3N2S2", "ENSBTAT00000066065", "Q5EA32", "ENSBTAT00000003922", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LTG6", "ENSBTAT00000070979", "F1MPF0", "ENSBTAT00000044081", "P79100", "ENSBTAT00000065392", "E1BAN3", "ENSBTAT00000033438", "F1N232", "ENSBTAT00000068680", "A0A3Q1M4W2", "ENSBTAT00000077611", "E1BDG0", "ENSBTAT00000022589", "E1BCP0", "ENSBTAT00000085000", "G5E522", "ENSBTAT00000002668", "E1B6Y9", "ENSBTAT00000002485", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10039604": { "compartment": "compartment_70616", "id": "reaction_10039604", "reactome": "R-BTA-170026", "name": "Protons are translocated from the intermembrane space to the matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163953" ], "products": [ "species_113529" ], "modifiers": [ [ "species_10039233", "catalyst" ], [ "species_30495", "catalyst" ], [ "species_170037", "inhibitor" ] ], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_113592", "species_29370", "species_29420", "species_29438" ] }, "reaction_10039240": { "compartment": "compartment_70616", "id": "reaction_10039240", "reactome": "R-BTA-166214", "name": "FA anion flip-flops to the opposite surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039235" ], "products": [ "species_10039237" ], "modifiers": [ [ "species_10039235", "catalyst" ] ], "additional_components": [ "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039242": { "compartment": "compartment_70616", "id": "reaction_10039242", "reactome": "R-BTA-166220", "name": "FA anion diffuses laterally to UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039233", "species_166213" ], "products": [ "species_10039235" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10039254": { "compartment": "compartment_70616", "id": "reaction_10039254", "reactome": "R-BTA-166387", "name": "The FA anion diffuses away laterally from UCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039237" ], "products": [ "species_166216", "species_10039233" ], "modifiers": [], "additional_components": [ "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810", "species_166216", "E1BME0", "ENSBTAT00000021691", "Q2KIJ0", "ENSBTAT00000021633", "Q3SZI5", "ENSBTAT00000004810" ] }, "reaction_10073400": { "compartment": "compartment_7660", "id": "reaction_10073400", "reactome": "R-BTA-5661122", "name": "JMJD6 demethylates Me2R3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073398", "species_113671", "species_113685" ], "products": [ "species_10066894", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10066651": { "compartment": "compartment_7660", "id": "reaction_10066651", "reactome": "R-BTA-3214912", "name": "KDM1A, KDM1B demethylate MeK5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066642" ], "products": [ "species_10066644", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10073402": { "compartment": "compartment_7660", "id": "reaction_10073402", "reactome": "R-BTA-5661123", "name": "KDM1A, KDM1B demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069756" ], "products": [ "species_10066642", "species_29478" ], "modifiers": [ [ "species_10066648", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076721" ] }, "reaction_10069754": { "compartment": "compartment_7660", "id": "reaction_10069754", "reactome": "R-BTA-4754176", "name": "JMJD6 demethylates MeR3-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066894", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025492" ] }, "reaction_10073404": { "compartment": "compartment_7660", "id": "reaction_10073404", "reactome": "R-BTA-5661124", "name": "JMJD6 demethylates MeR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070273", "species_113671", "species_113685" ], "products": [ "species_10035060", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000025492" ] }, "reaction_10073406": { "compartment": "compartment_7660", "id": "reaction_10073406", "reactome": "R-BTA-5661125", "name": "JMJD6 demethylates Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_113671", "species_113685" ], "products": [ "species_10070273", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069751", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000025492" ] }, "reaction_10069747": { "compartment": "compartment_7660", "id": "reaction_10069747", "reactome": "R-BTA-4724284", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069723" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10073394": { "compartment": "compartment_7660", "id": "reaction_10073394", "reactome": "R-BTA-5661120", "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069811", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069721" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073396": { "compartment": "compartment_7660", "id": "reaction_10073396", "reactome": "R-BTA-5661121", "name": "KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10072792" ], "products": [ "species_10069777", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10069719": { "compartment": "compartment_7660", "id": "reaction_10069719", "reactome": "R-BTA-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069712", "species_113671", "species_113685" ], "products": [ "species_10066644", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069769": { "compartment": "compartment_7660", "id": "reaction_10069769", "reactome": "R-BTA-4754181", "name": "KDM5A-D demethylate Me2K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10069756", "species_113685" ], "products": [ "species_10066642", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10073384": { "compartment": "compartment_7660", "id": "reaction_10073384", "reactome": "R-BTA-5661116", "name": "KDM5A-D demethylate Me3K5-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070949", "species_113671", "species_113685" ], "products": [ "species_29478", "species_10069756", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069766", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ57", "ENSBTAT00000071767", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10069740": { "compartment": "compartment_7660", "id": "reaction_10069740", "reactome": "R-BTA-4724279", "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069737", "catalyst" ] ], "additional_components": [ "A0A3Q1MT70", "ENSBTAT00000078784", "E1BB12", "ENSBTAT00000002234", "E1BPL5", "ENSBTAT00000002687", "A0A3Q1MI23", "ENSBTAT00000070121" ] }, "reaction_10073380": { "compartment": "compartment_7660", "id": "reaction_10073380", "reactome": "R-BTA-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10072735", "species_113685" ], "products": [ "species_10069712", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10069716", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002687" ] }, "reaction_10069796": { "compartment": "compartment_7660", "id": "reaction_10069796", "reactome": "R-BTA-4754187", "name": "KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069777", "species_113671", "species_113685" ], "products": [ "species_29478", "species_159942", "species_159939", "species_10069785" ], "modifiers": [ [ "species_10069793", "catalyst" ] ], "additional_components": [ "G3N2E9", "ENSBTAT00000063826", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10073382": { "compartment": "compartment_7660", "id": "reaction_10073382", "reactome": "R-BTA-5661115", "name": "KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10069721" ], "products": [ "species_29478", "species_159942", "species_10069723", "species_159939" ], "modifiers": [ [ "species_10069744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080313" ] }, "reaction_10069937": { "compartment": "compartment_7660", "id": "reaction_10069937", "reactome": "R-BTA-5159245", "name": "SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10066642" ], "modifiers": [ [ "species_10069934", "catalyst" ] ], "additional_components": [ "F1MUT0", "ENSBTAT00000004658", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072752": { "compartment": "compartment_7660", "id": "reaction_10072752", "reactome": "R-BTA-5638157", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069712" ], "products": [ "species_77502", "species_10072735" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072755": { "compartment": "compartment_7660", "id": "reaction_10072755", "reactome": "R-BTA-5638332", "name": "PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069785" ], "modifiers": [ [ "species_10044337", "catalyst" ] ], "additional_components": [ "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10069939": { "compartment": "compartment_7660", "id": "reaction_10069939", "reactome": "R-BTA-5159250", "name": "ATF7IP binds SETDB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069830", "species_10069834" ], "products": [ "species_10069836" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000107", "ENSBTAT00000086218", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10070962": { "compartment": "compartment_7660", "id": "reaction_10070962", "reactome": "R-BTA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069756" ], "products": [ "species_77502", "species_10070949" ], "modifiers": [ [ "species_10070959", "catalyst" ], [ "species_10070404", "inhibitor" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "G3X834", "ENSBTAT00000056084", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072725": { "compartment": "compartment_7660", "id": "reaction_10072725", "reactome": "R-BTA-5637686", "name": "WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066642" ], "products": [ "species_77502", "species_10069756" ], "modifiers": [ [ "species_10072722", "catalyst" ] ], "additional_components": [ "Q0P5C5", "ENSBTAT00000047138", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957" ] }, "reaction_10072788": { "compartment": "compartment_7660", "id": "reaction_10072788", "reactome": "R-BTA-5649799", "name": "DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072771" ], "products": [ "species_77502", "species_10072786" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072823": { "compartment": "compartment_7660", "id": "reaction_10072823", "reactome": "R-BTA-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072800" ], "products": [ "species_77502", "species_10072821" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10069846": { "compartment": "compartment_7660", "id": "reaction_10069846", "reactome": "R-BTA-4827383", "name": "WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10069712" ], "modifiers": [ [ "species_10069843", "catalyst" ] ], "additional_components": [ "ENSBTAT00000034204" ] }, "reaction_10072790": { "compartment": "compartment_7660", "id": "reaction_10072790", "reactome": "R-BTA-5649801", "name": "DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066644" ], "products": [ "species_77502", "species_10072763" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072778": { "compartment": "compartment_7660", "id": "reaction_10072778", "reactome": "R-BTA-5649764", "name": "DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072763" ], "products": [ "species_77502", "species_10072771" ], "modifiers": [ [ "species_10072775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082174" ] }, "reaction_10072813": { "compartment": "compartment_7660", "id": "reaction_10072813", "reactome": "R-BTA-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10064889" ], "products": [ "species_77502", "species_10072800" ], "modifiers": [ [ "species_10072810", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1M6A7", "ENSBTAT00000075432", "A0A3Q1MID6", "ENSBTAT00000070396" ] }, "reaction_10072655": { "compartment": "compartment_70101", "id": "reaction_10072655", "reactome": "R-BTA-5634802", "name": "MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10072636" ], "products": [ "species_10072642", "species_71285" ], "modifiers": [ [ "species_10072652", "catalyst" ] ], "additional_components": [ "A0A3Q1MWB8", "ENSBTAT00000079180", "F1MTF1", "ENSBTAT00000025245" ] }, "reaction_10069838": { "compartment": "compartment_7660", "id": "reaction_10069838", "reactome": "R-BTA-4827382", "name": "SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10069721" ], "products": [ "species_77502", "species_10069811" ], "modifiers": [ [ "species_10069825", "catalyst" ], [ "species_10069836", "catalyst" ] ], "additional_components": [ "F1N6Y5", "ENSBTAT00000022553", "F1MXG0", "ENSBTAT00000009641", "A0A452DJ38", "ENSBTAT00000013472", "A0A3Q1M7L9", "ENSBTAT00000086218", "E1BKH5", "ENSBTAT00000000107" ] }, "reaction_10072750": { "compartment": "compartment_7660", "id": "reaction_10072750", "reactome": "R-BTA-5638141", "name": "SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10072735" ], "products": [ "species_77502", "species_10072743" ], "modifiers": [ [ "species_10072747", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084416" ] }, "reaction_10068699": { "compartment": "compartment_7660", "id": "reaction_10068699", "reactome": "R-BTA-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068694", "catalyst" ], [ "species_10068697", "inhibitor" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068844": { "compartment": "compartment_7660", "id": "reaction_10068844", "reactome": "R-BTA-3782637", "name": "HDAC8 deacetylates histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10044720", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000070733" ] }, "reaction_10091745": { "compartment": "compartment_7660", "id": "reaction_10091745", "reactome": "R-BTA-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068694", "species_9679795" ], "products": [ "species_10068697" ], "modifiers": [], "additional_components": [ "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222", "A0A3Q1MMC8", "ENSBTAT00000063281", "E1B806", "ENSBTAT00000020692", "A0A3Q1LQ57", "ENSBTAT00000079478", "Q3MHL3", "ENSBTAT00000007758", "Q0VC01", "ENSBTAT00000075111", "A0A3Q1MC43", "ENSBTAT00000075576", "Q1LZE0", "ENSBTAT00000023526", "E1BGK1", "ENSBTAT00000025155", "F1MFL5", "ENSBTAT00000005222" ] }, "reaction_10068725": { "compartment": "compartment_7660", "id": "reaction_10068725", "reactome": "R-BTA-3777129", "name": "HDAC3 containing complexes deacetylate histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10068652" ], "products": [ "species_10068658", "species_5566518" ], "modifiers": [ [ "species_10068722", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "CHEBI:57627", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "F1MPA7", "ENSBTAT00000013888", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10068569": { "compartment": "compartment_7660", "id": "reaction_10068569", "reactome": "R-BTA-3662335", "name": "EP300 acetylates histone H2A, H2B, H3, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068132", "species_113560" ], "products": [ "species_2485002", "species_10068566" ], "modifiers": [ [ "species_10053052", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021556" ] }, "reaction_10067596": { "compartment": "compartment_7660", "id": "reaction_10067596", "reactome": "R-BTA-3321883", "name": "MSL acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035060", "species_113560" ], "products": [ "species_2485002", "species_10067575" ], "modifiers": [ [ "species_10067593", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "F1MP98", "ENSBTAT00000013893", "F1MRF9", "ENSBTAT00000000991", "E1BFW0", "ENSBTAT00000030541" ] }, "reaction_10071886": { "compartment": "compartment_7660", "id": "reaction_10071886", "reactome": "R-BTA-5579018", "name": "NCOA1(868-1441) binds PAX3(1-319)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071878", "species_10071882" ], "products": [ "species_10071884" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064008", "ENSBTAT00000013131", "F1MTX0", "ENSBTAT00000013131", "G3N0C2", "ENSBTAT00000064008" ] }, "reaction_10070409": { "compartment": "compartment_7660", "id": "reaction_10070409", "reactome": "R-BTA-5205824", "name": "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070394" ], "products": [ "species_77502", "species_10070404" ], "modifiers": [ [ "species_10070406", "catalyst" ] ], "additional_components": [ "A0A3Q1LQR4", "ENSBTAT00000066577", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070377": { "compartment": "compartment_7660", "id": "reaction_10070377", "reactome": "R-BTA-5205820", "name": "PRMT6 methylates arginine-4 of histone H2A (H2AR3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070328" ], "products": [ "species_77502", "species_10070374" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070520": { "compartment": "compartment_7660", "id": "reaction_10070520", "reactome": "R-BTA-5212679", "name": "DNMT3A binds Me2sR4-HIST1H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070419", "species_10044297" ], "products": [ "species_10070518" ], "modifiers": [], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "ENSBTAT00000086443", "A0A3Q1M9H4", "ENSBTAT00000086443", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717" ] }, "reaction_10073416": { "compartment": "compartment_7660", "id": "reaction_10073416", "reactome": "R-BTA-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070273" ], "products": [ "species_77502", "species_10073414" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070392": { "compartment": "compartment_7660", "id": "reaction_10070392", "reactome": "R-BTA-5205822", "name": "CARM1 methylates arginine-18 (H3R17) of histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070379" ], "products": [ "species_77502", "species_10070389" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070282": { "compartment": "compartment_7660", "id": "reaction_10070282", "reactome": "R-BTA-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10035060" ], "products": [ "species_77502", "species_10070273" ], "modifiers": [ [ "species_10070279", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1MR38", "ENSBTAT00000068896", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10070896": { "compartment": "compartment_7660", "id": "reaction_10070896", "reactome": "R-BTA-5229203", "name": "PRMT6 methylates histone H2A arginine-30 (H2AR29)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070848" ], "products": [ "species_77502", "species_10070894" ], "modifiers": [ [ "species_10070277", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009750" ] }, "reaction_10070757": { "compartment": "compartment_7660", "id": "reaction_10070757", "reactome": "R-BTA-5229010", "name": "CARM1 methylates arginine-27 of histone H3 (H3R26)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070745" ], "products": [ "species_77502", "species_10070755" ], "modifiers": [ [ "species_10047781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066577" ] }, "reaction_10070516": { "compartment": "compartment_7660", "id": "reaction_10070516", "reactome": "R-BTA-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10070467" ], "products": [ "species_77502", "species_10070513" ], "modifiers": [ [ "species_10066655", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068896" ] }, "reaction_10056383": { "compartment": "compartment_70101", "id": "reaction_10056383", "reactome": "R-BTA-1183128", "name": "PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1183111" ], "products": [ "species_29382", "species_1183191" ], "modifiers": [ [ "species_10056380", "catalyst" ] ], "additional_components": [ "species_74016", "A6QLC1", "ENSBTAT00000015977", "F1N048", "ENSBTAT00000004411", "E1BD46", "ENSBTAT00000015978", "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10066966": { "compartment": "compartment_7660", "id": "reaction_10066966", "reactome": "R-BTA-3247569", "name": "PADI4 deiminates Histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066920" ], "products": [ "species_10066951", "species_76230" ], "modifiers": [ [ "species_10066963", "catalyst" ] ], "additional_components": [ "E1BCN3", "ENSBTAT00000015991" ] }, "reaction_10092108": { "compartment": "compartment_24337", "id": "reaction_10092108", "reactome": "R-BTA-9705738", "name": "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092095", "species_10092091" ], "products": [ "species_10051733", "species_10055212", "species_10055148", "species_10055146", "species_10055162", "species_10092105" ], "modifiers": [ [ "species_10092091", "catalyst" ] ], "additional_components": [ "Q2TA10", "ENSBTAT00000055368", "Q1RMX2", "ENSBTAT00000055723", "A0A3Q1M5N0", "ENSBTAT00000066609", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "ENSBTAT00000002831", "ENSBTAT00000026036", "ENSBTAT00000078734", "ENSBTAT00000068692", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "A0A3Q1MXH0", "ENSBTAT00000068692", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036", "Q0P5F4", "ENSBTAT00000002831" ] }, "reaction_10092257": { "compartment": "compartment_24337", "id": "reaction_10092257", "reactome": "R-BTA-9707977", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092105" ], "products": [ "species_10092255" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "F1MCX4", "ENSBTAT00000015532", "F1N0D6", "ENSBTAT00000004101", "F1N261", "ENSBTAT00000075171", "P35833", "ENSBTAT00000028610", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1MYA3", "ENSBTAT00000072313", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10073690": { "compartment": "compartment_876", "id": "reaction_10073690", "reactome": "R-BTA-5668414", "name": "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039539", "species_10073673" ], "products": [ "species_10073687" ], "modifiers": [ [ "species_10073673", "catalyst" ] ], "additional_components": [ "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074280": { "compartment": "compartment_876", "id": "reaction_10074280", "reactome": "R-BTA-5675948", "name": "TNFRSF6B binds TNFSF6,14,15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074276", "species_10074270" ], "products": [ "species_10074278" ], "modifiers": [], "additional_components": [ "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452", "ENSBTAT00000028109", "A6QPW7", "ENSBTAT00000028109", "F1N0K4", "ENSBTAT00000045141", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10074266": { "compartment": "compartment_876", "id": "reaction_10074266", "reactome": "R-BTA-5675947", "name": "TNFSF18 binds TNFRSF18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074262", "species_10074258" ], "products": [ "species_10074264" ], "modifiers": [], "additional_components": [ "ENSBTAT00000064406", "ENSBTAT00000079425", "A0A3Q1M9X1", "ENSBTAT00000079425", "Q08DT5", "ENSBTAT00000064406" ] }, "reaction_10076237": { "compartment": "compartment_876", "id": "reaction_10076237", "reactome": "R-BTA-5693012", "name": "TNFSF15 binds TNFRSF25", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074274", "species_10076233" ], "products": [ "species_10076235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000036452", "ENSBTAT00000085571", "A0A3Q1LIC4", "ENSBTAT00000085571", "E1BF06", "ENSBTAT00000036452" ] }, "reaction_10073765": { "compartment": "compartment_876", "id": "reaction_10073765", "reactome": "R-BTA-5669035", "name": "TNFSF11 binds TNFRSF11A, B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073761" ], "products": [ "species_10073763" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009759", "A5D7R1", "ENSBTAT00000009759", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10076165": { "compartment": "compartment_876", "id": "reaction_10076165", "reactome": "R-BTA-5692315", "name": "OX40L binds OX40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076161", "species_10076155" ], "products": [ "species_10076163" ], "modifiers": [], "additional_components": [ "E1BGY4", "ENSBTAT00000003763", "ENSBTAT00000066801", "A0A3Q1M5M3", "ENSBTAT00000066801", "E1BGY4", "ENSBTAT00000003763" ] }, "reaction_10074340": { "compartment": "compartment_876", "id": "reaction_10074340", "reactome": "R-BTA-5676607", "name": "sBAFF,sAPRIL binds TACI,BCMA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074326", "species_10074336" ], "products": [ "species_10074338" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "F1MU29", "ENSBTAT00000020341", "A0A3Q1M673", "ENSBTAT00000085489", "B0LKN7", "ENSBTAT00000065347", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10074312": { "compartment": "compartment_876", "id": "reaction_10074312", "reactome": "R-BTA-5676593", "name": "TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073669", "species_10073585" ], "products": [ "species_10073671" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074314": { "compartment": "compartment_876", "id": "reaction_10074314", "reactome": "R-BTA-5676595", "name": "TRAFs bind RANK:RANKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073623", "species_10073585" ], "products": [ "species_10073625" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073757": { "compartment": "compartment_876", "id": "reaction_10073757", "reactome": "R-BTA-5669023", "name": "TWEAK binds FN14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073601", "species_10073597" ], "products": [ "species_10073603" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081383", "F1MX43", "ENSBTAT00000045584", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074316": { "compartment": "compartment_876", "id": "reaction_10074316", "reactome": "R-BTA-5676596", "name": "TRAF3 binds BAFFR:BAFF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073637", "species_10073585" ], "products": [ "species_10073639" ], "modifiers": [], "additional_components": [ "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074318": { "compartment": "compartment_876", "id": "reaction_10074318", "reactome": "R-BTA-5676598", "name": "TRAF2:cIAP1/2 complex binds FN14:TWEAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073603", "species_10073585" ], "products": [ "species_10073605" ], "modifiers": [], "additional_components": [ "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "E1B9D9", "ENSBTAT00000013869", "E1BL08", "ENSBTAT00000009316", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383" ] }, "reaction_10074320": { "compartment": "compartment_876", "id": "reaction_10074320", "reactome": "R-BTA-5676599", "name": "sBAFF trimer binds BAFFR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073635", "species_10073629" ], "products": [ "species_10073637" ], "modifiers": [], "additional_components": [ "B0LKN7", "ENSBTAT00000065347", "ENSBTAT00000037660", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347" ] }, "reaction_10074306": { "compartment": "compartment_876", "id": "reaction_10074306", "reactome": "R-BTA-5676589", "name": "RANKL,sRANKL trimer binds RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073621", "species_10073609" ], "products": [ "species_10074304" ], "modifiers": [], "additional_components": [ "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10074308": { "compartment": "compartment_876", "id": "reaction_10074308", "reactome": "R-BTA-5676591", "name": "2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073667", "species_10073643" ], "products": [ "species_10073669" ], "modifiers": [], "additional_components": [ "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "ENSBTAT00000020355", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141" ] }, "reaction_10074310": { "compartment": "compartment_876", "id": "reaction_10074310", "reactome": "R-BTA-5676592", "name": "2xRANK binds RANKL,sRANKL trimer:RANK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074304", "species_10073609" ], "products": [ "species_10073623" ], "modifiers": [], "additional_components": [ "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "ENSBTAT00000009960", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10073699": { "compartment": "compartment_876", "id": "reaction_10073699", "reactome": "R-BTA-5668454", "name": "K63polyUb-cIAP1,2 ubiquitinates TRAF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073687", "species_10052288" ], "products": [ "species_10073696" ], "modifiers": [ [ "species_10073687", "catalyst" ] ], "additional_components": [ "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745", "E1BL08", "ENSBTAT00000009316", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "E1B9D9", "ENSBTAT00000013869", "F1MX43", "ENSBTAT00000045584", "A0A3Q1LHY0", "ENSBTAT00000081383", "F1MJD0", "ENSBTAT00000037660", "B0LKN7", "ENSBTAT00000065347", "A6QQ46", "ENSBTAT00000020355", "Q06600", "ENSBTAT00000000018", "E1BK50", "ENSBTAT00000027554", "F1N0K4", "ENSBTAT00000045141", "F1MTC1", "ENSBTAT00000009960", "E1BIP0", "ENSBTAT00000011745" ] }, "reaction_10071948": { "compartment": "compartment_70101", "id": "reaction_10071948", "reactome": "R-BTA-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524" ], "products": [ "species_10047524" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10073708": { "compartment": "compartment_70101", "id": "reaction_10073708", "reactome": "R-BTA-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_29370", "species_10073705" ], "modifiers": [ [ "species_10047524", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000009316" ] }, "reaction_10071982": { "compartment": "compartment_70101", "id": "reaction_10071982", "reactome": "R-BTA-5607726", "name": "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10071979" ], "products": [ "species_29370", "species_10071971" ], "modifiers": [ [ "species_10071979", "catalyst" ] ], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316" ] }, "reaction_10072030": { "compartment": "compartment_7660", "id": "reaction_10072030", "reactome": "R-BTA-5607741", "name": "p52:RELB translocates from cytosol to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071991" ], "products": [ "species_10072028" ], "modifiers": [], "additional_components": [ "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "F1MBB0", "ENSBTAT00000055496", "A7MBB7", "ENSBTAT00000007904" ] }, "reaction_10071975": { "compartment": "compartment_70101", "id": "reaction_10071975", "reactome": "R-BTA-5607723", "name": "SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10071971" ], "products": [ "species_10071973" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "A7MBB7", "ENSBTAT00000007904", "F1MBB0", "ENSBTAT00000055496", "E1BL08", "ENSBTAT00000009316", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10057834": { "compartment": "compartment_70101", "id": "reaction_10057834", "reactome": "R-BTA-1370500", "name": "PRLR binds SCF beta-TrCP complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043873", "species_10054520" ], "products": [ "species_10054522" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10054524": { "compartment": "compartment_984", "id": "reaction_10054524", "reactome": "R-BTA-976991", "name": "Prolactin receptor ligands bind the prolactin receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054501", "species_10054509" ], "products": [ "species_10054511" ], "modifiers": [ [ "species_10054522", "inhibitor" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10060412": { "compartment": "compartment_876", "id": "reaction_10060412", "reactome": "R-BTA-1671687", "name": "PRLR activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054511" ], "products": [ "species_10054511" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10057836": { "compartment": "compartment_876", "id": "reaction_10057836", "reactome": "R-BTA-1370505", "name": "PRLR is phosphorylated at Ser-349", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054520" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10057823": { "compartment": "compartment_876", "id": "reaction_10057823", "reactome": "R-BTA-1364044", "name": "PRLR:JAK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054507" ], "products": [ "species_10054509" ], "modifiers": [], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10056335": { "compartment": "compartment_876", "id": "reaction_10056335", "reactome": "R-BTA-1170539", "name": "Prolactin receptor is internalized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054522" ], "products": [ "species_10043873", "species_10056333" ], "modifiers": [], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "species_29426", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986" ] }, "reaction_10054791": { "compartment": "compartment_876", "id": "reaction_10054791", "reactome": "R-BTA-982810", "name": "JAK2 phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10054511" ], "products": [ "species_29370", "species_10054785" ], "modifiers": [ [ "species_10054789", "catalyst" ] ], "additional_components": [ "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426", "A0A3Q1M283", "ENSBTAT00000082398", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "P01239", "ENSBTAT00000020313", "species_29426" ] }, "reaction_10054779": { "compartment": "compartment_984", "id": "reaction_10054779", "reactome": "R-BTA-982765", "name": "Growth hormone forms dimers and oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048427" ], "products": [ "species_10054777" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082606", "A0A3Q1LZG1", "ENSBTAT00000082606" ] }, "reaction_10056268": { "compartment": "compartment_876", "id": "reaction_10056268", "reactome": "R-BTA-1169192", "name": "PTP1B dephosphorylates GHR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10056255" ], "products": [ "species_29372", "species_10056265" ], "modifiers": [ [ "species_10056255", "catalyst" ] ], "additional_components": [ "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678", "A6QQN2", "ENSBTAT00000008678", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A0A3Q1LZG1", "ENSBTAT00000082606", "E1BCP6", "ENSBTAT00000015986", "A6QQN2", "ENSBTAT00000008678" ] }, "reaction_10090844": { "compartment": "compartment_876", "id": "reaction_10090844", "reactome": "R-BTA-9604767", "name": "FLT3LG dimer:FLT3 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10084303" ], "products": [ "species_29370", "species_10036552" ], "modifiers": [ [ "species_10084303", "catalyst" ], [ "species_10090842", "inhibitor" ], [ "species_10090840", "inhibitor" ] ], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092151": { "compartment": "compartment_876", "id": "reaction_10092151", "reactome": "R-BTA-9706336", "name": "Active FLT3 binds to SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10036552" ], "products": [ "species_10092149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10092159": { "compartment": "compartment_876", "id": "reaction_10092159", "reactome": "R-BTA-9706344", "name": "FLT3 phosphorylates GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092135", "species_113592" ], "products": [ "species_29370", "species_10092156" ], "modifiers": [ [ "species_10092135", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10077790": { "compartment": "compartment_876", "id": "reaction_10077790", "reactome": "R-BTA-6786789", "name": "FLT3LG dimer binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036540", "species_10077786" ], "products": [ "species_10077788" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10084305": { "compartment": "compartment_876", "id": "reaction_10084305", "reactome": "R-BTA-8854736", "name": "FLT3LG dimer:FLT3 binds FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077788", "species_10077786" ], "products": [ "species_10084303" ], "modifiers": [], "additional_components": [ "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "ENSBTAT00000024717", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962" ] }, "reaction_10092040": { "compartment": "compartment_876", "id": "reaction_10092040", "reactome": "R-BTA-9698408", "name": "PTPRJ dephosphorylates active FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10036552" ], "products": [ "species_10092037", "species_29372" ], "modifiers": [ [ "species_10080697", "catalyst" ], [ "species_29408", "inhibitor" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "ENSBTAT00000081330" ] }, "reaction_10092139": { "compartment": "compartment_876", "id": "reaction_10092139", "reactome": "R-BTA-9706315", "name": "Active FLT3 binds to SH2B3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055924", "species_10036552" ], "products": [ "species_10092112" ], "modifiers": [], "additional_components": [ "ENSBTAT00000079236", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092173": { "compartment": "compartment_876", "id": "reaction_10092173", "reactome": "R-BTA-9706350", "name": "FLT3 phosphorylates CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10092110" ], "products": [ "species_29370", "species_10092170" ], "modifiers": [ [ "species_10092110", "catalyst" ] ], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092141": { "compartment": "compartment_876", "id": "reaction_10092141", "reactome": "R-BTA-9706319", "name": "Active FLT3 binds to SLA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092116", "species_10036552" ], "products": [ "species_10092118" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400" ] }, "reaction_10092143": { "compartment": "compartment_876", "id": "reaction_10092143", "reactome": "R-BTA-9706323", "name": "Active FLT3 binds to SLA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092122", "species_10036552" ], "products": [ "species_10092124" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137" ] }, "reaction_10092126": { "compartment": "compartment_876", "id": "reaction_10092126", "reactome": "R-BTA-9706293", "name": "Active FLT3 binds to CBL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040359", "species_10036552" ], "products": [ "species_10092110" ], "modifiers": [ [ "species_10092118", "catalyst" ], [ "species_10092124", "catalyst" ], [ "species_10092112", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MHK8", "ENSBTAT00000081400", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q5BIM7", "ENSBTAT00000026137", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10092147": { "compartment": "compartment_876", "id": "reaction_10092147", "reactome": "R-BTA-9706330", "name": "Active FLT3 binds to SOCS6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087926", "species_10036552" ], "products": [ "species_10092145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023144", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKN8", "ENSBTAT00000023144" ] }, "reaction_10092195": { "compartment": "compartment_876", "id": "reaction_10092195", "reactome": "R-BTA-9706364", "name": "Internalization of ubiquitinated FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092178" ], "products": [ "species_10092193" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092183": { "compartment": "compartment_876", "id": "reaction_10092183", "reactome": "R-BTA-9706354", "name": "Ubiquitination of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10036552" ], "products": [ "species_10092178" ], "modifiers": [ [ "species_10092180", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LN00", "ENSBTAT00000072559" ] }, "reaction_10092137": { "compartment": "compartment_876", "id": "reaction_10092137", "reactome": "R-BTA-9706308", "name": "Active FLT3 binds to GRB10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084145", "species_10036552" ], "products": [ "species_10092135" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081071", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10092043": { "compartment": "compartment_70101", "id": "reaction_10092043", "reactome": "R-BTA-9699578", "name": "Active FLT3 phosphorylates CDKN1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499", "species_113592" ], "products": [ "species_29370", "species_10083560" ], "modifiers": [ [ "species_10036552", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717" ] }, "reaction_10092033": { "compartment": "compartment_876", "id": "reaction_10092033", "reactome": "R-BTA-9698170", "name": "Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036565", "species_10035515" ], "products": [ "species_10065275" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533", "ENSBTAT00000072391", "P32871", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1M864", "ENSBTAT00000084533" ] }, "reaction_10092133": { "compartment": "compartment_876", "id": "reaction_10092133", "reactome": "R-BTA-9706304", "name": "Active FLT3 binds to GRAP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046947", "species_10036552" ], "products": [ "species_10092131" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020161", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "E1BKA6", "ENSBTAT00000020161" ] }, "reaction_10092165": { "compartment": "compartment_876", "id": "reaction_10092165", "reactome": "R-BTA-9706345", "name": "Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092161", "species_10035515" ], "products": [ "species_10092163" ], "modifiers": [], "additional_components": [ "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "A0A3Q1LNN8", "ENSBTAT00000081071", "ENSBTAT00000072391", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "P32871", "ENSBTAT00000072391", "A0A3Q1LNN8", "ENSBTAT00000081071" ] }, "reaction_10090916": { "compartment": "compartment_70101", "id": "reaction_10090916", "reactome": "R-BTA-9607301", "name": "Active FLT3:GRB2 binds SOS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035489", "species_10036554" ], "products": [ "species_10074033" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015471", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10090919": { "compartment": "compartment_70101", "id": "reaction_10090919", "reactome": "R-BTA-9607304", "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10074033", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A2VE24", "ENSBTAT00000006962", "F1MRU0", "ENSBTAT00000024717", "Q3T0F9", "ENSBTAT00000006216", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10052217": { "compartment": "compartment_70101", "id": "reaction_10052217", "reactome": "R-BTA-909726", "name": "Phosphorylation of STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052144", "species_113592", "species_10051758" ], "products": [ "species_10052194", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ], [ "species_10047046", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000084342", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1M739", "ENSBTAT00000077529", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10052347": { "compartment": "compartment_13231", "id": "reaction_10052347", "reactome": "R-BTA-913529", "name": "Translocation of p-STAT1:p-STAT1 dimer to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051766" ], "products": [ "species_10052345" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10052189": { "compartment": "compartment_13231", "id": "reaction_10052189", "reactome": "R-BTA-909721", "name": "Translocation of ISGF3 complex to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052169" ], "products": [ "species_10052181" ], "modifiers": [ [ "species_10052187", "catalyst" ] ], "additional_components": [ "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "Q58DC4", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10055946": { "compartment": "compartment_70101", "id": "reaction_10055946", "reactome": "R-BTA-997309", "name": "Dephosphorylation of STAT1 by SHP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052194" ], "products": [ "species_10055943", "species_29372" ], "modifiers": [ [ "species_10040231", "catalyst" ] ], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000002653" ] }, "reaction_10055955": { "compartment": "compartment_70101", "id": "reaction_10055955", "reactome": "R-BTA-997311", "name": "Dephosphorylation of TYK2 by PTP1B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10052222" ], "products": [ "species_29372", "species_10055948" ], "modifiers": [ [ "species_10055952", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000008678" ] }, "reaction_10055958": { "compartment": "compartment_70101", "id": "reaction_10055958", "reactome": "R-BTA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10055948" ], "products": [ "species_29372", "species_10052206" ], "modifiers": [ [ "species_10043836", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "ENSBTAT00000077529" ] }, "reaction_10052159": { "compartment": "compartment_70101", "id": "reaction_10052159", "reactome": "R-BTA-909719", "name": "Recruitment of STAT2 to p-IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052140", "species_10052153" ], "products": [ "species_10052157" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10070719": { "compartment": "compartment_5460", "id": "reaction_10070719", "reactome": "R-BTA-5223305", "name": "ABCE1 binds RNASEL, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070711", "species_10070715" ], "products": [ "species_10070717" ], "modifiers": [], "additional_components": [ "A5H027", "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10052147": { "compartment": "compartment_70101", "id": "reaction_10052147", "reactome": "R-BTA-909718", "name": "Formation of p-STAT1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10051758" ], "products": [ "species_10051766", "species_29370" ], "modifiers": [ [ "species_10052144", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084342", "A0A3Q1ME65", "ENSBTAT00000084342", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052210": { "compartment": "compartment_876", "id": "reaction_10052210", "reactome": "R-BTA-909724", "name": "Recruitment of IFNAR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052204", "species_10052200" ], "products": [ "species_10052206" ], "modifiers": [ [ "species_10052208", "inhibitor" ] ], "additional_components": [ "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052213": { "compartment": "compartment_70101", "id": "reaction_10052213", "reactome": "R-BTA-909725", "name": "Interaction of IRF9 with p-STAT2:p-STAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052167", "species_10052163" ], "products": [ "species_10052169" ], "modifiers": [], "additional_components": [ "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "ENSBTAT00000036455", "Q58DC4", "ENSBTAT00000036455", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749" ] }, "reaction_10052233": { "compartment": "compartment_70101", "id": "reaction_10052233", "reactome": "R-BTA-909730", "name": "Phosphorylation of INFAR1 by TYK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052222" ], "products": [ "species_29370", "species_10052153" ], "modifiers": [ [ "species_10052222", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10091725": { "compartment": "compartment_70101", "id": "reaction_10091725", "reactome": "R-BTA-9678737", "name": "IFNAR1:TYK2 binds TYK2 inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678619", "species_10052200" ], "products": [ "species_10052208" ], "modifiers": [], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080" ] }, "reaction_10052236": { "compartment": "compartment_70101", "id": "reaction_10052236", "reactome": "R-BTA-909732", "name": "Phosphorylation of STAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052157" ], "products": [ "species_29370", "species_10052144" ], "modifiers": [ [ "species_10052157", "catalyst" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "E1B8Z4", "ENSBTAT00000005749", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052229": { "compartment": "compartment_70101", "id": "reaction_10052229", "reactome": "R-BTA-909729", "name": "Activation of JAK kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10052206" ], "products": [ "species_29370", "species_10052222" ], "modifiers": [ [ "species_10052206", "catalyst" ], [ "species_10052227", "inhibitor" ] ], "additional_components": [ "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "E1B8Z4", "ENSBTAT00000005749", "F1N0D6", "ENSBTAT00000004101", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1MSN0", "ENSBTAT00000005753", "Q9BEG9", "ENSBTAT00000011106", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10052196": { "compartment": "compartment_70101", "id": "reaction_10052196", "reactome": "R-BTA-909722", "name": "Release of p-STAT2:p-STAT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052194" ], "products": [ "species_10052167", "species_10052153" ], "modifiers": [], "additional_components": [ "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216", "A0A3Q1ME65", "ENSBTAT00000084342", "E1B8Z4", "ENSBTAT00000005749", "F1MCX4", "ENSBTAT00000015532", "Q04790", "ENSBTAT00000029080", "F1N0D6", "ENSBTAT00000004101", "E1B8Z4", "ENSBTAT00000005749", "E1B7E8", "ENSBTAT00000053863", "E1BDZ1", "ENSBTAT00000030158", "F1N6A7", "ENSBTAT00000054467", "A0A3Q1MMI8", "ENSBTAT00000073168", "G3MYH9", "ENSBTAT00000064849", "A0A3Q1LPD3", "ENSBTAT00000066449", "A0A3Q1LZ20", "ENSBTAT00000085216" ] }, "reaction_10056297": { "compartment": "compartment_70101", "id": "reaction_10056297", "reactome": "R-BTA-1169405", "name": "ISGylation of protein phosphatase 1 beta (PP2CB)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056293", "species_113592" ], "products": [ "species_111294", "species_10056295", "species_10056276", "species_10053116", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000050064", "O02741", "ENSBTAT00000019573", "O62830", "ENSBTAT00000050064", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056315": { "compartment": "compartment_70101", "id": "reaction_10056315", "reactome": "R-BTA-1169406", "name": "ISGylation of host proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10056311", "species_113592" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_76577", "species_10056313" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056283": { "compartment": "compartment_70101", "id": "reaction_10056283", "reactome": "R-BTA-1169394", "name": "ISGylation of IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10039246" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056280", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000031869", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "Q4JF28", "ENSBTAT00000031869", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060730": { "compartment": "compartment_70101", "id": "reaction_10060730", "reactome": "R-BTA-1678842", "name": "Competitive inhibition of translation initiation by ISGylated 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060726", "species_10060706" ], "products": [ "species_10060724", "species_10060728" ], "modifiers": [], "additional_components": [ "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1NEI6", "ENSBTAT00000068997", "A0A3Q1MFK0", "ENSBTAT00000075646", "A0A3Q1M8U3", "ENSBTAT00000086252", "Q2NL22", "ENSBTAT00000021327", "Q3SZ54", "ENSBTAT00000000144", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060732": { "compartment": "compartment_70101", "id": "reaction_10060732", "reactome": "R-BTA-1678843", "name": "ISGylation of protein translation regulator 4EHP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_10060704" ], "products": [ "species_10060706" ], "modifiers": [], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "A0A3Q1LSC2", "ENSBTAT00000086202", "A0A3Q1MRS1", "ENSBTAT00000086202", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056287": { "compartment": "compartment_70101", "id": "reaction_10056287", "reactome": "R-BTA-1169402", "name": "ISGylation of E2 conjugating enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056278", "species_113592", "species_10055358" ], "products": [ "species_111294", "species_10056276", "species_10053116", "species_10056285", "species_76577" ], "modifiers": [ [ "species_10056278", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000084854", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A3Q1MAR8", "ENSBTAT00000084854", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10056289": { "compartment": "compartment_70101", "id": "reaction_10056289", "reactome": "R-BTA-1169403", "name": "Interaction of E3 ligase with ISG15:E2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056276", "species_10056270" ], "products": [ "species_10056278" ], "modifiers": [], "additional_components": [ "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A2VEA3", "ENSBTAT00000008822", "A0A3Q1LPN8", "ENSBTAT00000083455" ] }, "reaction_10060694": { "compartment": "compartment_70101", "id": "reaction_10060694", "reactome": "R-BTA-1678841", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056313" ], "products": [ "species_10056311", "species_141681" ], "modifiers": [ [ "species_10060689", "catalyst" ] ], "additional_components": [ "O02741", "ENSBTAT00000019573", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "F1MM71", "ENSBTAT00000010366", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1ME65", "ENSBTAT00000084342", "A0A3Q1MAR8", "ENSBTAT00000084854", "F1N0D6", "ENSBTAT00000004101", "ENSBTAT00000086230" ] }, "reaction_10089341": { "compartment": "compartment_70101", "id": "reaction_10089341", "reactome": "R-BTA-8985153", "name": "OASL binds DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10089337" ], "products": [ "species_10089339" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "ENSBTAT00000004270", "F1MXX7", "ENSBTAT00000004270", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10089696": { "compartment": "compartment_70101", "id": "reaction_10089696", "reactome": "R-BTA-9009936", "name": "RNASEL cleaves cellular ssRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_170292" ], "products": [ "species_9009945" ], "modifiers": [ [ "species_10089693", "catalyst" ] ], "additional_components": [ "A5H027", "ENSBTAT00000044248", "species_113592" ] }, "reaction_10089349": { "compartment": "compartment_70101", "id": "reaction_10089349", "reactome": "R-BTA-8985201", "name": "ABCE1 binds RNASEL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089345", "species_10089343" ], "products": [ "species_10089347" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044248", "ENSBTAT00000048747", "A4IFE6", "ENSBTAT00000048747", "A5H027", "ENSBTAT00000044248" ] }, "reaction_10089703": { "compartment": "compartment_70101", "id": "reaction_10089703", "reactome": "R-BTA-9009950", "name": "PDE12 cleaves 2'-5' oligoadenylates ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8983696" ], "products": [ "species_70106", "species_113592", "species_76577" ], "modifiers": [ [ "species_10089700", "catalyst" ] ], "additional_components": [ "species_113592", "ENSBTAT00000020675" ] }, "reaction_10057588": { "compartment": "compartment_876", "id": "reaction_10057588", "reactome": "R-BTA-1296348", "name": "Activation of TWIK-related K+ channel (TREK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057585", "catalyst" ] ], "additional_components": [ "A0A3Q1LQ50", "ENSBTAT00000074252", "E1BGH7", "ENSBTAT00000011399", "F1MLI5", "ENSBTAT00000025779" ] }, "reaction_10091423": { "compartment": "compartment_70101", "id": "reaction_10091423", "reactome": "R-BTA-9647643", "name": "GSDMD (1-275) binds bacterial cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647661", "species_10037243" ], "products": [ "species_10091421" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092350": { "compartment": "compartment_70101", "id": "reaction_10092350", "reactome": "R-BTA-9710106", "name": "ELANE cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10092343", "species_10092345" ], "modifiers": [ [ "species_10092347", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000064480" ] }, "reaction_10091409": { "compartment": "compartment_876", "id": "reaction_10091409", "reactome": "R-BTA-9647619", "name": "GSDMD forms ringshaped oligomers ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081899" ], "products": [ "species_10081901" ], "modifiers": [ [ "species_10052773", "inhibitor" ], [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "Q3T0U5", "ENSBTAT00000018429", "Q3SX42", "ENSBTAT00000010436", "Q2HJ35", "ENSBTAT00000006291", "A2VDY3", "ENSBTAT00000008352", "Q08E32", "ENSBTAT00000017812", "Q58CS7", "ENSBTAT00000018071", "Q148L0", "ENSBTAT00000018623", "A6H704", "ENSBTAT00000017987", "ENSBTAT00000087110" ] }, "reaction_10081905": { "compartment": "compartment_984", "id": "reaction_10081905", "reactome": "R-BTA-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044670" ], "products": [ "species_10081502" ], "modifiers": [ [ "species_10081901", "catalyst" ], [ "species_10081903", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024094", "ENSBTAT00000024094", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092341": { "compartment": "compartment_70101", "id": "reaction_10092341", "reactome": "R-BTA-9710101", "name": "CASP4, CASP5 cleave GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10092338", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "O75601", "ENSBTAT00000027820" ] }, "reaction_10091415": { "compartment": "compartment_70101", "id": "reaction_10091415", "reactome": "R-BTA-9647631", "name": "GSDMD (1-275) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037243" ], "products": [ "species_10091413" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10091439": { "compartment": "compartment_70101", "id": "reaction_10091439", "reactome": "R-BTA-9647680", "name": "CASP1 cleaves GSDMD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091431" ], "products": [ "species_10037243", "species_10091433" ], "modifiers": [ [ "species_10050026", "catalyst" ], [ "species_10091437", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000087110", "ENSBTAT00000087110", "ENSBTAT00000087110", "A0A3Q1MFA5", "ENSBTAT00000072083", "ENSBTAT00000087110" ] }, "reaction_10091425": { "compartment": "compartment_70101", "id": "reaction_10091425", "reactome": "R-BTA-9647645", "name": "GSDMD oligomerizes into arc-, slit-shaped structures", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091413", "species_10037243" ], "products": [ "species_10081899" ], "modifiers": [ [ "species_10091407", "inhibitor" ] ], "additional_components": [ "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000087110" ] }, "reaction_10092352": { "compartment": "compartment_70101", "id": "reaction_10092352", "reactome": "R-BTA-9710254", "name": "GSDME oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091427", "species_10037249" ], "products": [ "species_10081903" ], "modifiers": [], "additional_components": [ "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10092354": { "compartment": "compartment_70101", "id": "reaction_10092354", "reactome": "R-BTA-9710263", "name": "GZMB cleaves GSDME", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091417" ], "products": [ "species_10037249", "species_10091419" ], "modifiers": [ [ "species_10037615", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000080428", "ENSBTAT00000013262" ] }, "reaction_10091429": { "compartment": "compartment_70101", "id": "reaction_10091429", "reactome": "R-BTA-9647660", "name": "GSDME (1-270) binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5620974", "species_10037249" ], "products": [ "species_10091427" ], "modifiers": [], "additional_components": [ "species_179838", "species_1806180", "species_6810412", "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_179838", "species_1806180", "species_6810412" ] }, "reaction_10037253": { "compartment": "compartment_17906", "id": "reaction_10037253", "reactome": "R-BTA-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037239" ], "products": [ "species_10037211" ], "modifiers": [ [ "species_10037235", "catalyst" ], [ "species_10037245", "catalyst" ], [ "species_10037251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q05KI7", "ENSBTAT00000000549", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10092356": { "compartment": "compartment_70101", "id": "reaction_10092356", "reactome": "R-BTA-9710353", "name": "GSDMD (1-275) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037243" ], "products": [ "species_10037245" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087110", "A0A3Q1MD51", "ENSBTAT00000087110", "species_8954419" ] }, "reaction_10092358": { "compartment": "compartment_70101", "id": "reaction_10092358", "reactome": "R-BTA-9710354", "name": "GSDME (1-270) binds cardiolipin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8954419", "species_10037249" ], "products": [ "species_10037251" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080428", "E1BFC3", "ENSBTAT00000080428", "species_8954419" ] }, "reaction_10091817": { "compartment": "compartment_70101", "id": "reaction_10091817", "reactome": "R-BTA-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678991", "species_10039151" ], "products": [ "species_10091815" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010928", "P18203", "ENSBTAT00000010928" ] }, "reaction_10056239": { "compartment": "compartment_876", "id": "reaction_10056239", "reactome": "R-BTA-1168636", "name": "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10056236", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LSU3", "ENSBTAT00000068365", "E1BG59", "ENSBTAT00000029159", "species_6797635" ] }, "reaction_10044568": { "compartment": "compartment_7660", "id": "reaction_10044568", "reactome": "R-BTA-264865", "name": "Caspase-mediated cleavage of Lamin A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044551" ], "products": [ "species_10044555", "species_10044553" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023373", "ENSBTAT00000023373", "ENSBTAT00000023373", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10090575": { "compartment": "compartment_13231", "id": "reaction_10090575", "reactome": "R-BTA-9029690", "name": "Caspase-6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044753" ], "products": [ "species_10044565" ], "modifiers": [], "additional_components": [ "G3X702", "ENSBTAT00000016642", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044578": { "compartment": "compartment_7660", "id": "reaction_10044578", "reactome": "R-BTA-264871", "name": "Caspase-mediated cleavage of Lamin B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044572" ], "products": [ "species_10044576", "species_10044574" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075973", "ENSBTAT00000075973", "ENSBTAT00000075973", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10036080": { "compartment": "compartment_7660", "id": "reaction_10036080", "reactome": "R-BTA-77586", "name": "Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036074" ], "products": [ "species_10036078", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1N0Z1", "ENSBTAT00000074628", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10036915": { "compartment": "compartment_7660", "id": "reaction_10036915", "reactome": "R-BTA-111437", "name": "Cleavage of the 3'-end of the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036911" ], "products": [ "species_10036913", "species_10036072" ], "modifiers": [], "additional_components": [ "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000" ] }, "reaction_10083967": { "compartment": "compartment_876", "id": "reaction_10083967", "reactome": "R-BTA-8852010", "name": "BTNL2 binds activated T cells surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083963" ], "products": [ "species_10083965" ], "modifiers": [], "additional_components": [ "ENSBTAT00000049415", "A6QNP4", "ENSBTAT00000049415" ] }, "reaction_10083959": { "compartment": "compartment_876", "id": "reaction_10083959", "reactome": "R-BTA-8851988", "name": "BTN2A2 binds T cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851965", "species_10083955" ], "products": [ "species_10083957" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045031", "F1MZI6", "ENSBTAT00000045031" ] }, "reaction_10046811": { "compartment": "compartment_876", "id": "reaction_10046811", "reactome": "R-BTA-388811", "name": "CD28 homodimer binds B7-1 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046779", "species_10046793" ], "products": [ "species_10046809" ], "modifiers": [], "additional_components": [ "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1ND77", "ENSBTAT00000079588" ] }, "reaction_10046907": { "compartment": "compartment_70101", "id": "reaction_10046907", "reactome": "R-BTA-388831", "name": "Phosphorylation of CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037459", "species_113592", "species_10046905" ], "products": [ "species_10046818", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015730", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10047530": { "compartment": "compartment_70101", "id": "reaction_10047530", "reactome": "R-BTA-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047524", "species_113592" ], "products": [ "species_10047527", "species_29370" ], "modifiers": [ [ "species_10047008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009316", "ENSBTAT00000009316", "ENSBTAT00000080762" ] }, "reaction_10046932": { "compartment": "compartment_70101", "id": "reaction_10046932", "reactome": "R-BTA-389158", "name": "CD28 bound PI3K phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10046929", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046787": { "compartment": "compartment_876", "id": "reaction_10046787", "reactome": "R-BTA-388808", "name": "CD28 homodimer binds B7-2 monomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046783", "species_10046779" ], "products": [ "species_10046785" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1ND77", "ENSBTAT00000079588", "A0A3Q1MLL9", "ENSBTAT00000081673" ] }, "reaction_10046943": { "compartment": "compartment_70101", "id": "reaction_10046943", "reactome": "R-BTA-389354", "name": "Activation of Vav1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10046936" ], "products": [ "species_29370", "species_10046940" ], "modifiers": [ [ "species_10037459", "catalyst" ] ], "additional_components": [ "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "species_179838", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000015730" ] }, "reaction_10046822": { "compartment": "compartment_70101", "id": "reaction_10046822", "reactome": "R-BTA-388814", "name": "Grb2 binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10035485" ], "products": [ "species_10046820" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000006216", "Q3T0F9", "ENSBTAT00000006216", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046951": { "compartment": "compartment_70101", "id": "reaction_10046951", "reactome": "R-BTA-389381", "name": "Gads binds CD28", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046818", "species_10046947" ], "products": [ "species_10046949" ], "modifiers": [], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730", "ENSBTAT00000020161", "E1BKA6", "ENSBTAT00000020161", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3Q1ND77", "ENSBTAT00000079588", "A0JNB0", "ENSBTAT00000015730" ] }, "reaction_10046834": { "compartment": "compartment_876", "id": "reaction_10046834", "reactome": "R-BTA-388817", "name": "ICOS binds ICOSL/B7-H2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046830", "species_10046826" ], "products": [ "species_10046832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019810", "ENSBTAT00000028775", "Q58DF9", "ENSBTAT00000028775", "E1BCU8", "ENSBTAT00000019810" ] }, "reaction_10046909": { "compartment": "compartment_70101", "id": "reaction_10046909", "reactome": "R-BTA-388833", "name": "Phosphorylation of CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046805", "species_113592", "species_10043788" ], "products": [ "species_29370", "species_10046899", "species_10041566" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10046959": { "compartment": "compartment_70101", "id": "reaction_10046959", "reactome": "R-BTA-389532", "name": "PP2A binds CTLA4 homodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046801", "species_10041566" ], "products": [ "species_10046803" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046807": { "compartment": "compartment_876", "id": "reaction_10046807", "reactome": "R-BTA-388809", "name": "CTLA-4 binds B7-1/B7-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046803", "species_10046795" ], "products": [ "species_10046805" ], "modifiers": [], "additional_components": [ "Q28090", "ENSBTAT00000017527", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527" ] }, "reaction_10046903": { "compartment": "compartment_70101", "id": "reaction_10046903", "reactome": "R-BTA-388829", "name": "SHP2 phosphatase binds CTLA-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10046899" ], "products": [ "species_10046901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "A0A3S5ZP81", "ENSBTAT00000079899", "A0A3Q1MLL9", "ENSBTAT00000081673", "Q28090", "ENSBTAT00000017527", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10075923": { "compartment": "compartment_876", "id": "reaction_10075923", "reactome": "R-BTA-5690669", "name": "CD22 binds itself to form homo-oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075919" ], "products": [ "species_10075921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081458", "A0A3Q1NI55", "ENSBTAT00000081458" ] }, "reaction_10065019": { "compartment": "compartment_453088", "id": "reaction_10065019", "reactome": "R-BTA-2213241", "name": "Formation of nonameric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065015", "species_10064164" ], "products": [ "species_10065017" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178" ] }, "reaction_10064219": { "compartment": "compartment_161320", "id": "reaction_10064219", "reactome": "R-BTA-2130504", "name": "Cleavage of lip22 to lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063931" ], "products": [ "species_10063937" ], "modifiers": [ [ "species_10064216", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "P25326", "ENSBTAT00000022774" ] }, "reaction_10065051": { "compartment": "compartment_161320", "id": "reaction_10065051", "reactome": "R-BTA-2213244", "name": "Loading of antigenic peptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065047", "species_2213226" ], "products": [ "species_10065045", "species_10065049" ], "modifiers": [], "additional_components": [ "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10065021": { "compartment": "compartment_20699", "id": "reaction_10065021", "reactome": "R-BTA-2213243", "name": "Fusion of COPII vesicle with Golgi complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064275" ], "products": [ "species_10064116", "species_10064225" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064221": { "compartment": "compartment_161320", "id": "reaction_10064221", "reactome": "R-BTA-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10065055": { "compartment": "compartment_17938", "id": "reaction_10065055", "reactome": "R-BTA-2213246", "name": "Disassociation of CLIP from MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065045", "species_10063941" ], "products": [ "species_10065047", "species_10065053" ], "modifiers": [], "additional_components": [ "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MHT7", "ENSBTAT00000008504", "Q5KTP6", "ENSBTAT00000065976", "F1MLV2", "ENSBTAT00000020881", "Q58DW7", "ENSBTAT00000016520", "ENSBTAT00000074178" ] }, "reaction_10065009": { "compartment": "compartment_24337", "id": "reaction_10065009", "reactome": "R-BTA-2213235", "name": "Trafficking of nonameric complex in the endocytic pathway", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065007" ], "products": [ "species_10063925" ], "modifiers": [], "additional_components": [ "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1ML60", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1N610", "ENSBTAT00000026100", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884" ] }, "reaction_10084401": { "compartment": "compartment_876", "id": "reaction_10084401", "reactome": "R-BTA-8856157", "name": "LAG3 (CD233) binds MHC II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064210", "species_10084397" ], "products": [ "species_10084399" ], "modifiers": [], "additional_components": [ "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "ENSBTAT00000077596", "A0A3Q1LYZ8", "ENSBTAT00000077596", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10065011": { "compartment": "compartment_453088", "id": "reaction_10065011", "reactome": "R-BTA-2213239", "name": "Formation of MHC II alpha beta heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064162", "species_10064138" ], "products": [ "species_10064164" ], "modifiers": [], "additional_components": [ "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064277": { "compartment": "compartment_13959", "id": "reaction_10064277", "reactome": "R-BTA-2130731", "name": "Formation of COPII vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064225", "species_10064223" ], "products": [ "species_10064275" ], "modifiers": [], "additional_components": [ "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q30309", "ENSBTAT00000014072", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "Q3T0T7", "ENSBTAT00000028280", "species_29438", "A6QNT8", "ENSBTAT00000043111", "F1MV07", "ENSBTAT00000004721", "F1MVW5", "ENSBTAT00000004831", "Q3ZCC9", "ENSBTAT00000023702" ] }, "reaction_10064118": { "compartment": "compartment_263163", "id": "reaction_10064118", "reactome": "R-BTA-2130393", "name": "Transport of MHC II:Ii complex along Golgi to TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064116" ], "products": [ "species_10064020" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064214": { "compartment": "compartment_876", "id": "reaction_10064214", "reactome": "R-BTA-2130500", "name": "Insertion of MHC II:Ii complex in to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064066" ], "products": [ "species_10064212" ], "modifiers": [], "additional_components": [ "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954" ] }, "reaction_10064068": { "compartment": "compartment_13946", "id": "reaction_10064068", "reactome": "R-BTA-2130378", "name": "Transport of MHC II:Ii complex to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064020" ], "products": [ "species_10064066" ], "modifiers": [], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1ML60", "ENSBTAT00000085256", "A0A3Q1M088", "ENSBTAT00000075226", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "F1MJU5", "ENSBTAT00000018484", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "A0A3Q1MEG8", "ENSBTAT00000074178", "A6QQE7", "ENSBTAT00000003342", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "Q30309", "ENSBTAT00000014072" ] }, "reaction_10063972": { "compartment": "compartment_161320", "id": "reaction_10063972", "reactome": "R-BTA-2130349", "name": "Generation of CLIP from lip10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063937" ], "products": [ "species_10063941" ], "modifiers": [ [ "species_10063969", "catalyst" ] ], "additional_components": [ "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A3Q1MEG8", "ENSBTAT00000074178", "E1BLZ1", "ENSBTAT00000034283", "F1N0X9", "ENSBTAT00000019800", "A6H6Y1", "ENSBTAT00000019939", "A6QQE7", "ENSBTAT00000003342", "Q30309", "ENSBTAT00000014072", "F1N610", "ENSBTAT00000026100", "G3MWT2", "ENSBTAT00000064718", "Q70IB5", "ENSBTAT00000063954", "F1MJU5", "ENSBTAT00000018484", "A0A3Q1M088", "ENSBTAT00000075226", "F1ML60", "ENSBTAT00000085256", "A0A3Q1MI49", "ENSBTAT00000085256", "A0A3Q1MUX0", "ENSBTAT00000078884", "A0A452DK38", "ENSBTAT00000036427", "P25326", "ENSBTAT00000022774", "Q0VCU3", "ENSBTAT00000014587" ] }, "reaction_10042635": { "compartment": "compartment_876", "id": "reaction_10042635", "reactome": "R-BTA-199154", "name": "CD200 binds to CD200R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042631", "species_10042627" ], "products": [ "species_10042633" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027169", "ENSBTAT00000001635", "A5D7V5", "ENSBTAT00000001635", "Q3ZC60", "ENSBTAT00000027169" ] }, "reaction_10042253": { "compartment": "compartment_876", "id": "reaction_10042253", "reactome": "R-BTA-199032", "name": "MADCAM1-1 binds Integrin alpha4beta7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042245", "species_10042249" ], "products": [ "species_10042251" ], "modifiers": [], "additional_components": [ "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279", "ENSBTAT00000068738", "A0A3Q1MBF2", "ENSBTAT00000068738", "F1MEF6", "ENSBTAT00000012194", "F6RKH9", "ENSBTAT00000025279" ] }, "reaction_10042623": { "compartment": "compartment_876", "id": "reaction_10042623", "reactome": "R-BTA-199112", "name": "CRTAM binds to NECL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042615", "species_10042619" ], "products": [ "species_10042621" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076490", "ENSBTAT00000083396", "A0A3Q1M4X8", "ENSBTAT00000083396", "A7YWT5", "ENSBTAT00000076490" ] }, "reaction_10042129": { "compartment": "compartment_876", "id": "reaction_10042129", "reactome": "R-BTA-198955", "name": "TCR complex interacts with peptide antigen-presenting MHC Class I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042125", "species_10042061" ], "products": [ "species_10042127" ], "modifiers": [], "additional_components": [ "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MD45", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "A0A3Q1MG36", "ENSBTAT00000082227", "F1MZQ5", "ENSBTAT00000035878", "A0A3Q1MIV3", "ENSBTAT00000081596", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MUW6", "ENSBTAT00000080813", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "F1MC47", "ENSBTAT00000046313", "A0A3Q1M3D2", "ENSBTAP00000064618", "F1MBP3", "ENSBTAT00000050022", "A0A3Q1MT21", "ENSBTAT00000067721", "F1MJB8", "ENSBTAT00000054092", "E1BLJ5", "ENSBTAT00000055909", "A0A3Q1MYX4", "ENSBTAT00000085379", "Q0VCU4", "ENSBTAT00000016878", "Q28072", "ENSBTAT00000008462", "A7MAZ7", "ENSBTAT00000028175", "A7YW30", "ENSBTAT00000033046" ] }, "reaction_10074993": { "compartment": "compartment_876", "id": "reaction_10074993", "reactome": "R-BTA-5685607", "name": "Sialic acid binds SIGLEC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006168", "species_10074989" ], "products": [ "species_10074991" ], "modifiers": [], "additional_components": [ "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "species_1006168" ] }, "reaction_10075009": { "compartment": "compartment_876", "id": "reaction_10075009", "reactome": "R-BTA-5685608", "name": "CLEC2B binds KLRF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074999", "species_10075005" ], "products": [ "species_10075007" ], "modifiers": [], "additional_components": [ "A5PJG8", "ENSBTAT00000042955", "A0A3Q1NBN7", "ENSBTAT00000082969", "A0A3Q1NBN7", "ENSBTAT00000082969", "A5PJG8", "ENSBTAT00000042955" ] }, "reaction_10084672": { "compartment": "compartment_876", "id": "reaction_10084672", "reactome": "R-BTA-8862090", "name": "PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084640", "species_10084668" ], "products": [ "species_10084670" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001412", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "E1B7F4", "ENSBTAT00000017867", "A6H6Y6", "ENSBTAT00000065575", "F1MJX3", "ENSBTAT00000001412" ] }, "reaction_10074899": { "compartment": "compartment_876", "id": "reaction_10074899", "reactome": "R-BTA-5685603", "name": "SAP and EAT2 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074895", "species_10074889" ], "products": [ "species_10074897" ], "modifiers": [], "additional_components": [ "F1MLN1", "ENSBTAT00000034482", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "Q3ZBB1", "ENSBTAT00000036966", "A0A3Q1M4F1", "ENSBTAT00000085516", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10076963": { "compartment": "compartment_876", "id": "reaction_10076963", "reactome": "R-BTA-5696358", "name": "TREM,CD300 binds lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696348", "species_10076959" ], "products": [ "species_10076961" ], "modifiers": [], "additional_components": [ "species_428256", "species_1500646", "species_1602375", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "F1MNL2", "ENSBTAT00000020853", "A0A3Q1NAW3", "ENSBTAT00000070846", "E1BI56", "ENSBTAT00000008500", "F1MGI2", "ENSBTAT00000010642", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1LX01", "ENSBTAT00000070885", "F1MG16", "ENSBTAT00000003593", "A0A3Q1MT87", "ENSBTAT00000077738", "species_428256", "species_1500646", "species_1602375" ] }, "reaction_10042786": { "compartment": "compartment_876", "id": "reaction_10042786", "reactome": "R-BTA-199579", "name": "KIR2DL4 interacting with HLA-G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042782", "species_10042780" ], "products": [ "species_10042784" ], "modifiers": [], "additional_components": [ "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "G5E5W5", "ENSBTAT00000011326", "Q8SPQ5", "ENSBTAT00000080712", "A0A3Q1ME80", "ENSBTAT00000077038", "A0A3Q1MQ30", "ENSBTAT00000081128", "F1MQD8", "ENSBTAT00000053352", "G3X797", "ENSBTAT00000022538", "G5E5B4", "ENSBTAT00000011326", "G5E5G6", "ENSBTAT00000018094", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813" ] }, "reaction_10084658": { "compartment": "compartment_876", "id": "reaction_10084658", "reactome": "R-BTA-8862084", "name": "PILRA,PILRB bind CD99", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084654", "species_10084650" ], "products": [ "species_10084656" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087222", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1MN37", "ENSBTAT00000072757", "F1MJX3", "ENSBTAT00000001412", "A0A3Q1NN33", "ENSBTAT00000087222" ] }, "reaction_10074901": { "compartment": "compartment_876", "id": "reaction_10074901", "reactome": "R-BTA-5685604", "name": "SLAMF6 binds SLAMF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074893" ], "products": [ "species_10074895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000034482", "F1MLN1", "ENSBTAT00000034482" ] }, "reaction_10043241": { "compartment": "compartment_70101", "id": "reaction_10043241", "reactome": "R-BTA-202354", "name": "Translocation of PLC-gamma1 to PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043234", "species_179856" ], "products": [ "species_10043239" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023383", "species_6810412", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043262": { "compartment": "compartment_70101", "id": "reaction_10043262", "reactome": "R-BTA-202407", "name": "PLC-gamma1 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10043259", "catalyst" ] ], "additional_components": [ "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383" ] }, "reaction_10043193": { "compartment": "compartment_70101", "id": "reaction_10043193", "reactome": "R-BTA-202203", "name": "Recruitment of PI3K to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043189", "species_10035523" ], "products": [ "species_10043191" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074583", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043225": { "compartment": "compartment_70101", "id": "reaction_10043225", "reactome": "R-BTA-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043006", "species_112275" ], "products": [ "species_10043223" ], "modifiers": [], "additional_components": [ "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043219": { "compartment": "compartment_70101", "id": "reaction_10043219", "reactome": "R-BTA-202237", "name": "Hydrolysis of PIP3 to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10043216", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077857" ] }, "reaction_10043252": { "compartment": "compartment_70101", "id": "reaction_10043252", "reactome": "R-BTA-202394", "name": "Translocation of CARMA1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043248", "species_10043180" ], "products": [ "species_10043250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043304": { "compartment": "compartment_70101", "id": "reaction_10043304", "reactome": "R-BTA-202489", "name": "Oligomerization of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043279", "species_10043295" ], "products": [ "species_10043281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043274": { "compartment": "compartment_876", "id": "reaction_10043274", "reactome": "R-BTA-202443", "name": "Oligomerization of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043267", "species_10043265" ], "products": [ "species_10043272" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10043244": { "compartment": "compartment_70101", "id": "reaction_10043244", "reactome": "R-BTA-202365", "name": "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10043191", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1MCW9", "ENSBTAT00000074583" ] }, "reaction_10043212": { "compartment": "compartment_876", "id": "reaction_10043212", "reactome": "R-BTA-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10043209" ], "modifiers": [ [ "species_10043180", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043182": { "compartment": "compartment_70101", "id": "reaction_10043182", "reactome": "R-BTA-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202277", "species_10043178" ], "products": [ "species_10043180" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "ENSBTAT00000039221", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221" ] }, "reaction_10043298": { "compartment": "compartment_70101", "id": "reaction_10043298", "reactome": "R-BTA-202459", "name": "Phosphorylation of Bcl10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10043293" ], "products": [ "species_29370", "species_10043295" ], "modifiers": [ [ "species_10041331", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000020312" ] }, "reaction_10043300": { "compartment": "compartment_70101", "id": "reaction_10043300", "reactome": "R-BTA-202466", "name": "Interaction of Bcl10 to CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043291", "species_10043272" ], "products": [ "species_10043293" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018398", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10043270": { "compartment": "compartment_70101", "id": "reaction_10043270", "reactome": "R-BTA-202437", "name": "Phosphorylation of CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043250", "species_113592" ], "products": [ "species_29370", "species_10043267" ], "modifiers": [ [ "species_10043209", "catalyst" ] ], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10043302": { "compartment": "compartment_70101", "id": "reaction_10043302", "reactome": "R-BTA-202472", "name": "Translocation of TRAF6 to CBM complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043287", "species_10039473" ], "products": [ "species_10043289" ], "modifiers": [], "additional_components": [ "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "ENSBTAT00000021630", "Q3ZCC3", "ENSBTAT00000021630", "species_1806238", "species_179838", "F1MQJ7", "ENSBTAT00000039221", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398" ] }, "reaction_10055448": { "compartment": "compartment_70101", "id": "reaction_10055448", "reactome": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055446" ], "products": [ "species_983123", "species_10055330" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055451": { "compartment": "compartment_70101", "id": "reaction_10055451", "reactome": "R-BTA-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055428", "species_113592", "species_10055422" ], "products": [ "species_111294", "species_10055446", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055428", "catalyst" ] ], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919" ] }, "reaction_10055453": { "compartment": "compartment_70101", "id": "reaction_10055453", "reactome": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055330", "species_10055422", "species_983035" ], "products": [ "species_10055424" ], "modifiers": [], "additional_components": [ "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10055491": { "compartment": "compartment_70101", "id": "reaction_10055491", "reactome": "R-BTA-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10055488", "catalyst" ] ], "additional_components": [ "A0A3Q1MAQ4", "ENSBTAT00000080071", "E1BP91", "ENSBTAT00000015199", "E1BL29", "ENSBTAT00000028490" ] }, "reaction_10055431": { "compartment": "compartment_70101", "id": "reaction_10055431", "reactome": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055424", "species_113592" ], "products": [ "species_111294", "species_10055428", "species_10055420", "species_76577" ], "modifiers": [ [ "species_10055330", "catalyst" ] ], "additional_components": [ "A0A3Q1N1X1", "ENSBTAT00000076465", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "A0A3Q1N1X1", "ENSBTAT00000076465", "A0A3Q1LK96", "ENSBTAT00000068172", "A0A3Q1M231", "ENSBTAT00000070128", "A0A3Q1LV49", "ENSBTAT00000082004", "Q1RMK0", "ENSBTAT00000010691", "F1N7A0", "ENSBTAT00000015476", "M5FKI3", "ENSBTAT00000070499", "F1MBM6", "ENSBTAT00000044404", "Q4U5R4", "ENSBTAT00000039156", "A0A3Q1LPN8", "ENSBTAT00000083455", "Q7YRV4", "ENSBTAT00000018459", "F1MEX6", "ENSBTAT00000010969", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A0A3Q1N1L9", "ENSBTAT00000073772", "Q58D00", "ENSBTAT00000085937", "A0A452DHW1", "ENSBTAT00000003178", "A0A3Q1MN48", "ENSBTAT00000078511", "A5PKK2", "ENSBTAT00000052368", "E1BK68", "ENSBTAT00000016959", "F6PQR5", "ENSBTAT00000046646", "A7MBH8", "ENSBTAT00000086266", "A0A3Q1LNU6", "ENSBTAT00000085125", "Q2KHT6", "ENSBTAT00000021554", "A0A452DI01", "ENSBTAT00000003249", "F1N1C5", "ENSBTAT00000019285", "F1N019", "ENSBTAT00000004177", "A0A3Q1MDP9", "ENSBTAT00000067912", "A0A3Q1MCW5", "ENSBTAT00000083919", "A0A3Q1LQM8", "ENSBTAT00000080785", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MLW5", "ENSBTAT00000080771", "A6QP22", "ENSBTAT00000025095", "A5PJX0", "ENSBTAT00000003665", "E1B9Q3", "ENSBTAT00000001868", "A0A3Q1LFJ4", "ENSBTAT00000086616", "A0A452DIC0", "ENSBTAT00000012776", "F1MDA7", "ENSBTAT00000027498", "A0A3Q1M118", "ENSBTAT00000075176", "F1MSC9", "ENSBTAT00000082146", "A0A3Q1M680", "ENSBTAT00000080715", "A0A452DIA2", "ENSBTAT00000011600", "E1BGE6", "ENSBTAT00000050675", "Q17QK6", "ENSBTAT00000009501", "F1MLX8", "ENSBTAT00000003367", "E1BBI7", "ENSBTAT00000081934", "A0A3Q1MUP8", "ENSBTAT00000079583", "F1N0S2", "ENSBTAT00000000291", "G3X7V0", "ENSBTAT00000009741", "F1N7C1", "ENSBTAT00000027362", "Q1JPC8", "ENSBTAT00000022612", "F1N5X8", "ENSBTAT00000048180", "E1B964", "ENSBTAT00000012816", "A6QQD1", "ENSBTAT00000005377", "E1BCZ2", "ENSBTAT00000012423" ] }, "reaction_10061657": { "compartment": "compartment_876", "id": "reaction_10061657", "reactome": "R-BTA-1973968", "name": "Beta-defensins 4A and 103 bind CCR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061653", "species_10045084" ], "products": [ "species_10061655" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "ENSBTAT00000018066", "A0A3S5ZP45", "ENSBTAT00000018066", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783" ] }, "reaction_10058456": { "compartment": "compartment_984", "id": "reaction_10058456", "reactome": "R-BTA-1467269", "name": "Beta-defensins bind microbial membranes causing disruption", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058452", "species_1462049" ], "products": [ "species_10058454" ], "modifiers": [], "additional_components": [ "Q50JB9", "ENSBTAT00000072863", "species_1462049", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10058492": { "compartment": "compartment_984", "id": "reaction_10058492", "reactome": "R-BTA-1471338", "name": "Beta-defensins 1, 4A and 103 bind CCR6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045160", "species_10058488" ], "products": [ "species_10058490" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "F1MT56", "ENSBTAT00000037034", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "Q28880", "ENSBTAT00000050266", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "E1BHH4", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10058486": { "compartment": "compartment_17963", "id": "reaction_10058486", "reactome": "R-BTA-1471322", "name": "Beta-defensins are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058484" ], "products": [ "species_10058452" ], "modifiers": [], "additional_components": [ "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q50JB9", "ENSBTAT00000072863" ] }, "reaction_10063801": { "compartment": "compartment_161320", "id": "reaction_10063801", "reactome": "R-BTA-2090037", "name": "IDUA hydrolyses Heparan sulfate chain(6)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090055" ], "products": [ "species_2090070", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10063803": { "compartment": "compartment_161320", "id": "reaction_10063803", "reactome": "R-BTA-2090038", "name": "NAGLU hydrolyses heparan chain(2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090053" ], "products": [ "species_1678743", "species_2065212" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10060634": { "compartment": "compartment_17938", "id": "reaction_10060634", "reactome": "R-BTA-1678660", "name": "HGSNAT oligomer acetylates Heparan sulfate chain(3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090040", "species_76183" ], "products": [ "species_2090069", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060685": { "compartment": "compartment_161320", "id": "reaction_10060685", "reactome": "R-BTA-1678742", "name": "NAGLU hydrolyses Heparan sulfate chain(4)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2090069" ], "products": [ "species_2090080", "species_1678743" ], "modifiers": [ [ "species_10060682", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071251" ] }, "reaction_10063805": { "compartment": "compartment_17938", "id": "reaction_10063805", "reactome": "R-BTA-2090085", "name": "HGSNAT oligomer acetylates Heparan chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_2090045" ], "products": [ "species_2090053", "species_76194" ], "modifiers": [ [ "species_10060631", "catalyst" ] ], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230" ] }, "reaction_10060671": { "compartment": "compartment_876", "id": "reaction_10060671", "reactome": "R-BTA-1678694", "name": "Heparanase 2 (HPSE2) cleaves heparan sulfate from its proteoglycan (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10060650" ], "products": [ "species_2090023", "species_10060664" ], "modifiers": [ [ "species_10060668", "catalyst" ] ], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "A0A3Q1LTY7", "ENSBTAT00000085269", "Q3ZBZ6", "ENSBTAT00000027192", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "ENSBTAT00000085333" ] }, "reaction_10063022": { "compartment": "compartment_876", "id": "reaction_10063022", "reactome": "R-BTA-2024084", "name": "HS-GAGs translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060650" ], "products": [ "species_10060394" ], "modifiers": [], "additional_components": [ "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1MZX8", "ENSBTAT00000011475", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "Q3ZBZ6", "ENSBTAT00000027192" ] }, "reaction_10060625": { "compartment": "compartment_161320", "id": "reaction_10060625", "reactome": "R-BTA-1678650", "name": "IDS hydrolyses Heparan sulfate chain(5)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090080", "species_1605715" ], "products": [ "species_2090055", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10060741": { "compartment": "compartment_161320", "id": "reaction_10060741", "reactome": "R-BTA-1678854", "name": "GUSB tetramer hydrolyses CS/HS precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065212" ], "products": [ "species_1678868", "species_2090075" ], "modifiers": [ [ "species_10060738", "catalyst" ], [ "species_427963", "inhibitor" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10060678": { "compartment": "compartment_161320", "id": "reaction_10060678", "reactome": "R-BTA-1678716", "name": "IDUA hydrolyses Heparan sulfate chain(1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2090033", "species_1605715" ], "products": [ "species_2090072", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10072894": { "compartment": "compartment_17963", "id": "reaction_10072894", "reactome": "R-BTA-5653878", "name": "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_964746" ], "products": [ "species_5653871", "species_205687" ], "modifiers": [ [ "species_10072891", "catalyst" ] ], "additional_components": [ "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10072898": { "compartment": "compartment_17963", "id": "reaction_10072898", "reactome": "R-BTA-5653886", "name": "B4GALT1 binds LALBA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072896", "species_10054442" ], "products": [ "species_10072891" ], "modifiers": [ [ "species_735682", "catalyst" ], [ "species_5653875", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066421", "ENSBTAT00000020286", "A0A3Q1LYQ2", "ENSBTAT00000066421", "P08037", "ENSBTAT00000020286" ] }, "reaction_10033611": { "compartment": "compartment_70101", "id": "reaction_10033611", "reactome": "R-BTA-70449", "name": "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_29578", "species_29360" ], "products": [ "species_70106", "species_29800", "species_73473" ], "modifiers": [ [ "species_10033608", "catalyst" ] ], "additional_components": [ "P10096", "ENSBTAT00000037753", "Q2KJE5", "ENSBTAT00000021166" ] }, "reaction_10080765": { "compartment": "compartment_70101", "id": "reaction_10080765", "reactome": "R-BTA-6799604", "name": "GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_449701" ], "products": [ "species_29512", "species_31633" ], "modifiers": [ [ "species_10080762", "catalyst" ] ], "additional_components": [ "A0A452DIC9", "ENSBTAT00000000357" ] }, "reaction_10033629": { "compartment": "compartment_70101", "id": "reaction_10033629", "reactome": "R-BTA-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_30014", "species_29370" ], "modifiers": [ [ "species_10033626", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_76190", "inhibitor" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "A1A4J1", "ENSBTAT00000056305" ] }, "reaction_10034157": { "compartment": "compartment_70101", "id": "reaction_10034157", "reactome": "R-BTA-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10034154", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_29358", "inhibitor" ], [ "species_30389", "inhibitor" ] ], "additional_components": [ "species_29926", "species_74126", "Q1JPG7", "ENSBTAT00000086042", "A5D984", "ENSBTAT00000047412" ] }, "reaction_10034140": { "compartment": "compartment_70101", "id": "reaction_10034140", "reactome": "R-BTA-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10034049", "catalyst" ] ], "additional_components": [ "Q3SZ62", "ENSBTAT00000032937" ] }, "reaction_10076815": { "compartment": "compartment_12045", "id": "reaction_10076815", "reactome": "R-BTA-5696021", "name": "ADPGK:Mg2+ phosphorylates Glc to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_70113" ], "products": [ "species_30537", "species_76577" ], "modifiers": [ [ "species_10076812", "catalyst" ] ], "additional_components": [ "species_29926", "A2VE47", "ENSBTAT00000002065" ] }, "reaction_10088737": { "compartment": "compartment_70101", "id": "reaction_10088737", "reactome": "R-BTA-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29800" ], "products": [ "species_70106", "species_8955759", "species_29728" ], "modifiers": [ [ "species_10033547", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926" ] }, "reaction_10033620": { "compartment": "compartment_70101", "id": "reaction_10033620", "reactome": "R-BTA-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10033617", "catalyst" ] ], "additional_components": [ "A0A452DIX3", "ENSBTAT00000026358" ] }, "reaction_10034071": { "compartment": "compartment_70101", "id": "reaction_10034071", "reactome": "R-BTA-71496", "name": "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014" ], "products": [ "species_29578", "species_75970" ], "modifiers": [ [ "species_10034066", "catalyst" ] ], "additional_components": [ "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416" ] }, "reaction_10078710": { "compartment": "compartment_70101", "id": "reaction_10078710", "reactome": "R-BTA-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10078707", "catalyst" ] ], "additional_components": [ "F1MX69", "ENSBTAT00000070308" ] }, "reaction_10045050": { "compartment": "compartment_70101", "id": "reaction_10045050", "reactome": "R-BTA-372843", "name": "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_113544" ], "products": [ "species_113548", "species_198498" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10033757": { "compartment": "compartment_5460", "id": "reaction_10033757", "reactome": "R-BTA-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_113552" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10041885": { "compartment": "compartment_70101", "id": "reaction_10041885", "reactome": "R-BTA-198513", "name": "Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10041882", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077820" ] }, "reaction_10045692": { "compartment": "compartment_70101", "id": "reaction_10045692", "reactome": "R-BTA-376851", "name": "Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_198498" ], "products": [ "species_29406", "species_113544" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10034238": { "compartment": "compartment_17957", "id": "reaction_10034238", "reactome": "R-BTA-71825", "name": "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10034235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013436" ] }, "reaction_10045043": { "compartment": "compartment_5460", "id": "reaction_10045043", "reactome": "R-BTA-372819", "name": "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113573", "species_113587" ], "products": [ "species_372364", "species_113525", "species_29376" ], "modifiers": [ [ "species_10045040", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015834" ] }, "reaction_10041878": { "compartment": "compartment_70101", "id": "reaction_10041878", "reactome": "R-BTA-198440", "name": "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_113544" ], "products": [ "species_113594", "species_198498" ], "modifiers": [ [ "species_10041875", "catalyst" ] ], "additional_components": [ "P22292", "ENSBTAT00000079666" ] }, "reaction_10033718": { "compartment": "compartment_70101", "id": "reaction_10033718", "reactome": "R-BTA-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29448" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10067254": { "compartment": "compartment_17957", "id": "reaction_10067254", "reactome": "R-BTA-3266566", "name": "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067251", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005552" ] }, "reaction_10067240": { "compartment": "compartment_70101", "id": "reaction_10067240", "reactome": "R-BTA-3257122", "name": "SLC37A1, SLC37A2 exchange G6P for Pi across the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113551", "species_30537" ], "products": [ "species_29372", "species_113782" ], "modifiers": [ [ "species_10067237", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069229" ] }, "reaction_10067247": { "compartment": "compartment_17957", "id": "reaction_10067247", "reactome": "R-BTA-3262512", "name": "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_113782" ], "products": [ "species_113551", "species_113780" ], "modifiers": [ [ "species_10067244", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021621" ] }, "reaction_10045029": { "compartment": "compartment_70101", "id": "reaction_10045029", "reactome": "R-BTA-372448", "name": "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113553" ], "products": [ "species_29448", "species_113552" ], "modifiers": [ [ "species_10045026", "catalyst" ] ], "additional_components": [ "A0A3Q1M9V5", "ENSBTAT00000083179", "A0A3Q1LHX4", "ENSBTAT00000073854" ] }, "reaction_10033638": { "compartment": "compartment_70101", "id": "reaction_10033638", "reactome": "R-BTA-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10033635", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "Q3SZB7", "ENSBTAT00000012835" ] }, "reaction_10033561": { "compartment": "compartment_70101", "id": "reaction_10033561", "reactome": "R-BTA-70333", "name": "KHK dimer phosphorylates Fru to Fru 1-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29532", "species_113592" ], "products": [ "species_29370", "species_31221" ], "modifiers": [ [ "species_10033558", "catalyst" ], [ "species_29804", "catalyst" ], [ "species_29370", "inhibitor" ] ], "additional_components": [ "Q0II75", "ENSBTAT00000015052" ] }, "reaction_10083115": { "compartment": "compartment_70101", "id": "reaction_10083115", "reactome": "R-BTA-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30393", "species_29360" ], "products": [ "species_6799497", "species_70106", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10033570": { "compartment": "compartment_70101", "id": "reaction_10033570", "reactome": "R-BTA-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_113592" ], "products": [ "species_29578", "species_29370" ], "modifiers": [ [ "species_10033567", "catalyst" ] ], "additional_components": [ "A0A3Q1MGZ4", "ENSBTAT00000085239", "species_29926" ] }, "reaction_10072825": { "compartment": "compartment_70101", "id": "reaction_10072825", "reactome": "R-BTA-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10041681", "catalyst" ] ], "additional_components": [ "A0A3Q1M9Q1", "ENSBTAT00000078546", "A0A3Q1MBL5", "ENSBTAT00000078546" ] }, "reaction_10063530": { "compartment": "compartment_20699", "id": "reaction_10063530", "reactome": "R-BTA-2046285", "name": "The keratan chain can be capped by N-acetylneuraminic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_10063528" ], "products": [ "species_10063493", "species_727810" ], "modifiers": [ [ "species_10054719", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324", "A5D960", "ENSBTAT00000001538", "Q6H8M9", "ENSBTAT00000086395" ] }, "reaction_10063485": { "compartment": "compartment_17963", "id": "reaction_10063485", "reactome": "R-BTA-2046180", "name": "KSPG is secreted from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063470" ], "products": [ "species_10063483" ], "modifiers": [], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854" ] }, "reaction_10063532": { "compartment": "compartment_20699", "id": "reaction_10063532", "reactome": "R-BTA-2046298", "name": "B4GALTs transfer Gal to a branch of keratan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063518" ], "products": [ "species_205687", "species_10063528" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063249": { "compartment": "compartment_20699", "id": "reaction_10063249", "reactome": "R-BTA-2025724", "name": "B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_914003", "species_10063230" ], "products": [ "species_205687", "species_10063240" ], "modifiers": [ [ "species_10063246", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "A7YY64", "ENSBTAT00000024024", "Q5EA01", "ENSBTAT00000030023", "A0A3Q1LX89", "ENSBTAT00000084108", "A0A3Q1LVP5", "ENSBTAT00000079485", "F1MSS4", "ENSBTAT00000005494" ] }, "reaction_10063232": { "compartment": "compartment_20699", "id": "reaction_10063232", "reactome": "R-BTA-2025723", "name": "B4GALTs transfer Gal to the N-glycan precursor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063222", "species_735682" ], "products": [ "species_10063230", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063520": { "compartment": "compartment_20699", "id": "reaction_10063520", "reactome": "R-BTA-2046265", "name": "B4GALTs transfer Gal to the keratan chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10063240" ], "products": [ "species_10063518", "species_205687" ], "modifiers": [ [ "species_10054464", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "F6RH18", "ENSBTAT00000047259", "P08037", "ENSBTAT00000020286", "E1BCQ2", "ENSBTAT00000061252", "F6RJ53", "ENSBTAT00000015761" ] }, "reaction_10063477": { "compartment": "compartment_20699", "id": "reaction_10063477", "reactome": "R-BTA-2046175", "name": "Further sulfation on galactose residues produces KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10063464" ], "products": [ "species_742343", "species_10063470" ], "modifiers": [ [ "species_10063474", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "ENSBTAT00000004844" ] }, "reaction_10063508": { "compartment": "compartment_20699", "id": "reaction_10063508", "reactome": "R-BTA-2046222", "name": "CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063493", "species_741440" ], "products": [ "species_742343", "species_10063464" ], "modifiers": [ [ "species_10063505", "catalyst" ] ], "additional_components": [ "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "P13605", "ENSBTAT00000019854", "Q05443", "ENSBTAT00000002279", "E1BMN6", "ENSBTAT00000015389", "E1BK55", "ENSBTAT00000056191" ] }, "reaction_10060825": { "compartment": "compartment_161320", "id": "reaction_10060825", "reactome": "R-BTA-1793182", "name": "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065213" ], "products": [ "species_2065269", "species_1606845" ], "modifiers": [ [ "species_10060622", "catalyst" ] ], "additional_components": [ "F1N2D5", "ENSBTAT00000014683", "species_74016" ] }, "reaction_10091289": { "compartment": "compartment_161320", "id": "reaction_10091289", "reactome": "R-BTA-9638075", "name": "HEXB cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10060827": { "compartment": "compartment_161320", "id": "reaction_10060827", "reactome": "R-BTA-1793186", "name": "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2105025" ], "products": [ "species_2104993", "species_1678617" ], "modifiers": [ [ "species_10060675", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075910" ] }, "reaction_10060842": { "compartment": "compartment_161320", "id": "reaction_10060842", "reactome": "R-BTA-1793209", "name": "HYAL1 hydrolyses Chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065257" ], "products": [ "species_2065212" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "CHEBI:63515", "species_2065239", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10060829": { "compartment": "compartment_161320", "id": "reaction_10060829", "reactome": "R-BTA-1793207", "name": "ARSB hydrolyses C4S/C6S chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2065251", "species_1605715" ], "products": [ "species_2065239", "species_1606845" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "CHEBI:63512", "CHEBI:63513", "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10062655": { "compartment": "compartment_984", "id": "reaction_10062655", "reactome": "R-BTA-2022056", "name": "DSPG and CSPG translocate to the lysosome for degradation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062551", "species_10062589" ], "products": [ "species_10062627", "species_10062653" ], "modifiers": [], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562" ] }, "reaction_10060031": { "compartment": "compartment_161320", "id": "reaction_10060031", "reactome": "R-BTA-1606789", "name": "ARSB hydrolyses DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065231" ], "products": [ "species_1606845", "species_2065213" ], "modifiers": [ [ "species_10060028", "catalyst" ] ], "additional_components": [ "A6QLZ3", "ENSBTAT00000010988", "species_74016" ] }, "reaction_10063807": { "compartment": "compartment_161320", "id": "reaction_10063807", "reactome": "R-BTA-2105001", "name": "HEXA cleaves the terminal GalNAc from DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2065269" ], "products": [ "species_1605658", "species_2105025" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10061642": { "compartment": "compartment_20699", "id": "reaction_10061642", "reactome": "R-BTA-1971487", "name": "CHPF,CHSY3 transfer GalNAc to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_10061629" ], "products": [ "species_10061574", "species_205687" ], "modifiers": [ [ "species_10061639", "catalyst" ] ], "additional_components": [ "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10061612": { "compartment": "compartment_20699", "id": "reaction_10061612", "reactome": "R-BTA-1971483", "name": "Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_10061591", "species_742343" ], "modifiers": [ [ "species_10061609", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1N663", "ENSBTAT00000014069", "A0A3Q1M362", "ENSBTAT00000073469", "A6QLZ9", "ENSBTAT00000011567", "A0A3Q1MTD8", "ENSBTAT00000068924" ] }, "reaction_10062463": { "compartment": "compartment_20699", "id": "reaction_10062463", "reactome": "R-BTA-2018682", "name": "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061574", "species_741440" ], "products": [ "species_742343", "species_10062450" ], "modifiers": [ [ "species_10062460", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "G3X6P1", "ENSBTAT00000010069", "E1BPN4", "ENSBTAT00000074793" ] }, "reaction_10061651": { "compartment": "compartment_20699", "id": "reaction_10061651", "reactome": "R-BTA-1971491", "name": "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061557" ], "products": [ "species_10061629", "species_205687" ], "modifiers": [ [ "species_10061648", "catalyst" ] ], "additional_components": [ "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "E1B9D0", "ENSBTAT00000019108", "E1BMM8", "ENSBTAT00000027366", "F1N783", "ENSBTAT00000019521" ] }, "reaction_10063014": { "compartment": "compartment_17963", "id": "reaction_10063014", "reactome": "R-BTA-2022911", "name": "CSPG is secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063012" ], "products": [ "species_10062589" ], "modifiers": [], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562" ] }, "reaction_10061402": { "compartment": "compartment_20699", "id": "reaction_10061402", "reactome": "R-BTA-1889981", "name": "B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061238", "species_735682" ], "products": [ "species_10061388", "species_205687" ], "modifiers": [ [ "species_10061399", "catalyst" ] ], "additional_components": [ "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000035663" ] }, "reaction_10061251": { "compartment": "compartment_20699", "id": "reaction_10061251", "reactome": "R-BTA-1878002", "name": "XYLTs transfer Xyl to core protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061200", "species_742361" ], "products": [ "species_10061238", "species_205687" ], "modifiers": [ [ "species_10061248", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MY84", "ENSBTAT00000016206", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q0VCM1", "ENSBTAT00000002979", "Q3ZBZ6", "ENSBTAT00000027192", "P21793", "ENSBTAT00000004562", "F1MZX8", "ENSBTAT00000011475", "F1N2Y8", "ENSBTAT00000002312", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "F1N211", "ENSBTAT00000007264", "A0A3Q1LSF3", "ENSBTAT00000070229" ] }, "reaction_10061395": { "compartment": "compartment_20699", "id": "reaction_10061395", "reactome": "R-BTA-1889978", "name": "B3GALT6 transfers Gal to the tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_10061388" ], "products": [ "species_205687", "species_10061289" ], "modifiers": [ [ "species_10061392", "catalyst" ] ], "additional_components": [ "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LZ29", "ENSBTAT00000082766", "Q3ZBZ6", "ENSBTAT00000027192", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1MZX8", "ENSBTAT00000011475", "F1MER7", "ENSBTAT00000022744", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "ENSBTAT00000057493" ] }, "reaction_10061350": { "compartment": "compartment_20699", "id": "reaction_10061350", "reactome": "R-BTA-1889955", "name": "B3GAT dimers transfer GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061347", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1M0B6", "ENSBTAT00000083529", "species_113527", "A0A3Q1LG25", "ENSBTAT00000080834", "F1MQ60", "ENSBTAT00000070592" ] }, "reaction_10091286": { "compartment": "compartment_20699", "id": "reaction_10091286", "reactome": "R-BTA-9638064", "name": "B3GAT3 dimer transfers GlcA to tetrasaccharide linker", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1889970", "species_10061289" ], "products": [ "species_10061327", "species_205687" ], "modifiers": [ [ "species_10061345", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "F1MER7", "ENSBTAT00000022744", "A0A3Q1N5R3", "ENSBTAT00000082452", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "A0A3Q1LTY7", "ENSBTAT00000085269", "A0A3Q1LZ29", "ENSBTAT00000082766", "E1BKS1", "ENSBTAT00000020125", "P21809", "ENSBTAT00000047242", "Q3ZBZ6", "ENSBTAT00000027192", "F1MZX8", "ENSBTAT00000011475", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "A0A3Q1LG25", "ENSBTAT00000080834", "species_113527" ] }, "reaction_10062697": { "compartment": "compartment_20699", "id": "reaction_10062697", "reactome": "R-BTA-2022063", "name": "CHST14 transfers SO4(2-) to GalNAc in dermatan or DS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062676", "species_741440" ], "products": [ "species_742343", "species_10062690" ], "modifiers": [ [ "species_10062694", "catalyst" ] ], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000005795" ] }, "reaction_10062701": { "compartment": "compartment_17963", "id": "reaction_10062701", "reactome": "R-BTA-2022065", "name": "DSPGs are secreted", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062699" ], "products": [ "species_10062551" ], "modifiers": [], "additional_components": [ "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312" ] }, "reaction_10062508": { "compartment": "compartment_20699", "id": "reaction_10062508", "reactome": "R-BTA-2022052", "name": "Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062465" ], "products": [ "species_10062501" ], "modifiers": [ [ "species_10062505", "catalyst" ] ], "additional_components": [ "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "ENSBTAT00000056960" ] }, "reaction_10062674": { "compartment": "compartment_20699", "id": "reaction_10062674", "reactome": "R-BTA-2022061", "name": "Dermatan sulfate can be further sulfated on position 2 of iduronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10062482" ], "products": [ "species_742343", "species_10062667" ], "modifiers": [ [ "species_10062671", "catalyst" ] ], "additional_components": [ "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "F1N2Y8", "ENSBTAT00000002312", "P21809", "ENSBTAT00000047242", "F1MY84", "ENSBTAT00000016206", "Q0VCM1", "ENSBTAT00000002979", "P21793", "ENSBTAT00000004562", "ENSBTAT00000068674" ] }, "reaction_10039887": { "compartment": "compartment_70101", "id": "reaction_10039887", "reactome": "R-BTA-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174370" ], "products": [ "species_29370", "species_158471" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10039890": { "compartment": "compartment_70101", "id": "reaction_10039890", "reactome": "R-BTA-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174375" ], "products": [ "species_111294", "species_174370" ], "modifiers": [ [ "species_10039884", "catalyst" ] ], "additional_components": [ "Q0VC88", "ENSBTAT00000070040", "F6R031", "ENSBTAT00000017229" ] }, "reaction_10051570": { "compartment": "compartment_20699", "id": "reaction_10051570", "reactome": "R-BTA-741449", "name": "SLC35B2,3 transport cytosolic PAPS to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471" ], "products": [ "species_741440" ], "modifiers": [ [ "species_10051567", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010620" ] }, "reaction_10048727": { "compartment": "compartment_876", "id": "reaction_10048727", "reactome": "R-BTA-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_427648" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10048724", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019462" ] }, "reaction_10064353": { "compartment": "compartment_876", "id": "reaction_10064353", "reactome": "R-BTA-2160851", "name": "HAS1,2,3 mediate the polymerisation of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2142867" ], "products": [ "species_2142896" ], "modifiers": [ [ "species_10064350", "catalyst" ] ], "additional_components": [ "species_2162224", "ENSBTAT00000071722" ] }, "reaction_10064393": { "compartment": "compartment_876", "id": "reaction_10064393", "reactome": "R-BTA-2160915", "name": "Receptor-mediated uptake of HA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064359", "species_10064373", "species_2160848" ], "products": [ "species_10064375" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070191", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "species_2162224", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10091291": { "compartment": "compartment_161320", "id": "reaction_10091291", "reactome": "R-BTA-9638076", "name": "HEXB cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059946", "catalyst" ] ], "additional_components": [ "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064593": { "compartment": "compartment_161320", "id": "reaction_10064593", "reactome": "R-BTA-2162225", "name": "HEXA cleaves the terminal GalNAc from small HA fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162223", "species_1605715" ], "products": [ "species_1678743", "species_2162224" ], "modifiers": [ [ "species_10059941", "catalyst" ] ], "additional_components": [ "Q0V8R6", "ENSBTAT00000017261", "H7BWW2", "ENSBTAT00000048411" ] }, "reaction_10064355": { "compartment": "compartment_161320", "id": "reaction_10064355", "reactome": "R-BTA-2160874", "name": "HYAL1 hydrolyses (HA)50", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160864" ], "products": [ "species_2160866" ], "modifiers": [ [ "species_10060839", "catalyst" ] ], "additional_components": [ "species_2162224", "species_2162224", "F1MSK8", "ENSBTAT00000000611" ] }, "reaction_10064595": { "compartment": "compartment_161320", "id": "reaction_10064595", "reactome": "R-BTA-2162226", "name": "GUSB tetramer hydrolyses GlcA-1,3-GlcNAc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2162224" ], "products": [ "species_1678743", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064597": { "compartment": "compartment_161320", "id": "reaction_10064597", "reactome": "R-BTA-2162227", "name": "GUSB tetramer hydrolyses (HA)2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_2160866" ], "products": [ "species_2162223", "species_1678868" ], "modifiers": [ [ "species_10060738", "catalyst" ] ], "additional_components": [ "species_2162224", "A3KMY8", "ENSBTAT00000000941" ] }, "reaction_10064391": { "compartment": "compartment_876", "id": "reaction_10064391", "reactome": "R-BTA-2160892", "name": "Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064388" ], "products": [ "species_2160894", "species_10064388" ], "modifiers": [ [ "species_10064388", "catalyst" ] ], "additional_components": [ "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "species_2162224", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191", "A0A3Q1LS44", "ENSBTAT00000071051", "species_74016", "species_2162224", "A0A3Q1MJE8", "ENSBTAT00000080269", "Q6UC88", "ENSBTAT00000001061", "F1MYW1", "ENSBTAT00000007896", "Q8SQG8", "ENSBTAT00000070191" ] }, "reaction_10033579": { "compartment": "compartment_70101", "id": "reaction_10033579", "reactome": "R-BTA-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10033576", "catalyst" ] ], "additional_components": [ "species_29360", "A0A452DIP2", "ENSBTAT00000006586" ] }, "reaction_10033594": { "compartment": "compartment_70101", "id": "reaction_10033594", "reactome": "R-BTA-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10033549", "catalyst" ] ], "additional_components": [ "A5PKH8", "ENSBTAT00000001019", "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10090620": { "compartment": "compartment_70101", "id": "reaction_10090620", "reactome": "R-BTA-9033959", "name": "ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735700", "species_9033793" ], "products": [ "species_205687", "species_9033802" ], "modifiers": [ [ "species_10090617", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090703": { "compartment": "compartment_17963", "id": "reaction_10090703", "reactome": "R-BTA-9036987", "name": "FUT2 transfers Fuc to Type 1 chains to form H antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9037036" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090638": { "compartment": "compartment_984", "id": "reaction_10090638", "reactome": "R-BTA-9034042", "name": "sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034046" ], "products": [ "species_417888", "species_9037066" ], "modifiers": [ [ "species_10090635", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090611": { "compartment": "compartment_17963", "id": "reaction_10090611", "reactome": "R-BTA-9033949", "name": "FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_205689", "species_9033793" ], "modifiers": [ [ "species_10090608", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023560" ] }, "reaction_10090645": { "compartment": "compartment_984", "id": "reaction_10090645", "reactome": "R-BTA-9034053", "name": "sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9034101", "species_9034065" ], "products": [ "species_417888", "species_9037067" ], "modifiers": [ [ "species_10090642", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1M8N6", "ENSBTAT00000081124" ] }, "reaction_10090631": { "compartment": "compartment_70101", "id": "reaction_10090631", "reactome": "R-BTA-9033961", "name": "ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735682", "species_9033793" ], "products": [ "species_9033798", "species_205687" ], "modifiers": [ [ "species_10090628", "catalyst" ] ], "additional_components": [ "A0A3Q1M8N6", "ENSBTAT00000081124", "species_113527" ] }, "reaction_10090856": { "compartment": "compartment_17963", "id": "reaction_10090856", "reactome": "R-BTA-9605644", "name": "FUT3 transfers Fuc to Type 1 DSGG to form dsLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605649", "species_205683" ], "products": [ "species_205689", "species_9605651" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090797": { "compartment": "compartment_17963", "id": "reaction_10090797", "reactome": "R-BTA-9603984", "name": "FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9033790", "species_205683" ], "products": [ "species_9605593", "species_205689" ], "modifiers": [ [ "species_10090794", "catalyst" ] ], "additional_components": [ "F1MDG4", "ENSBTAT00000056091", "F1MBS8", "ENSBTAT00000000529", "F1N751", "ENSBTAT00000010501" ] }, "reaction_10090799": { "compartment": "compartment_17963", "id": "reaction_10090799", "reactome": "R-BTA-9603986", "name": "FUT3 transfers Fuc to Type 1 chains to form LeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9036984", "species_205683" ], "products": [ "species_205689", "species_9605607" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090819": { "compartment": "compartment_17963", "id": "reaction_10090819", "reactome": "R-BTA-9603989", "name": "B3GALTs transfer Gal to GlcNAc-1,3-Gal-R to form Type 1 chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9604808", "species_735682" ], "products": [ "species_205687", "species_9036984" ], "modifiers": [ [ "species_10090816", "catalyst" ] ], "additional_components": [ "Q2HJA3", "ENSBTAT00000036248", "F1MSJ4", "ENSBTAT00000031889", "Q3T0R9", "ENSBTAT00000022206" ] }, "reaction_10090851": { "compartment": "compartment_17963", "id": "reaction_10090851", "reactome": "R-BTA-9605600", "name": "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9033790" ], "products": [ "species_727810", "species_9605685" ], "modifiers": [ [ "species_10090848", "catalyst" ] ], "additional_components": [ "A0A3Q1LUC6", "ENSBTAT00000078218", "A0A3Q1MGH3", "ENSBTAT00000075324" ] }, "reaction_10090867": { "compartment": "compartment_17963", "id": "reaction_10090867", "reactome": "R-BTA-9605682", "name": "FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605685", "species_205683" ], "products": [ "species_9605661", "species_205689" ], "modifiers": [ [ "species_10090864", "catalyst" ] ], "additional_components": [ "G3MZR2", "ENSBTAT00000066072", "F1MBS8", "ENSBTAT00000000529" ] }, "reaction_10090802": { "compartment": "compartment_17963", "id": "reaction_10090802", "reactome": "R-BTA-9603987", "name": "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9036984" ], "products": [ "species_727810", "species_9605595" ], "modifiers": [ [ "species_10054713", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078218" ] }, "reaction_10090772": { "compartment": "compartment_17963", "id": "reaction_10090772", "reactome": "R-BTA-9603982", "name": "FUT2 transfers Fuc to LeA to form LeB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605607", "species_205683" ], "products": [ "species_205689", "species_9605394" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090774": { "compartment": "compartment_17963", "id": "reaction_10090774", "reactome": "R-BTA-9603983", "name": "FUT2 transfers Fuc to LeX to form LeY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605593", "species_205683" ], "products": [ "species_205689", "species_9605586" ], "modifiers": [ [ "species_10090700", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028720" ] }, "reaction_10090854": { "compartment": "compartment_17963", "id": "reaction_10090854", "reactome": "R-BTA-9605609", "name": "FUT3 transfers Fuc to Type 1 MSGG to form sLeA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9605595", "species_205683" ], "products": [ "species_9605615", "species_205689" ], "modifiers": [ [ "species_10076419", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000529" ] }, "reaction_10090822": { "compartment": "compartment_17963", "id": "reaction_10090822", "reactome": "R-BTA-9603991", "name": "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727815", "species_9605595" ], "products": [ "species_727810", "species_9605649" ], "modifiers": [ [ "species_10069341", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061027" ] }, "reaction_10034041": { "compartment": "compartment_70101", "id": "reaction_10034041", "reactome": "R-BTA-71324", "name": "ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_73578" ], "products": [ "species_29882", "species_29578" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10033592": { "compartment": "compartment_70101", "id": "reaction_10033592", "reactome": "R-BTA-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537", "species_29366" ], "products": [ "species_70106", "species_31467", "species_29364" ], "modifiers": [ [ "species_10033589", "catalyst" ] ], "additional_components": [ "A0A3Q1MM55", "ENSBTAT00000067626", "species_113563" ] }, "reaction_10034043": { "compartment": "compartment_70101", "id": "reaction_10034043", "reactome": "R-BTA-71335", "name": "xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790", "species_29878" ], "products": [ "species_29578", "species_29512" ], "modifiers": [ [ "species_10034038", "catalyst" ] ], "additional_components": [ "species_29926", "species_29480", "A7Z014", "ENSBTAT00000004892" ] }, "reaction_10034013": { "compartment": "compartment_70101", "id": "reaction_10034013", "reactome": "R-BTA-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29996", "species_29366" ], "products": [ "species_70106", "species_113528", "species_29364", "species_29732" ], "modifiers": [ [ "species_10034010", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM3", "ENSBTAT00000017988" ] }, "reaction_10042801": { "compartment": "compartment_70101", "id": "reaction_10042801", "reactome": "R-BTA-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10034032": { "compartment": "compartment_70101", "id": "reaction_10034032", "reactome": "R-BTA-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10034029", "catalyst" ] ], "additional_components": [ "species_71067", "A5D7P1", "ENSBTAT00000082970" ] }, "reaction_10088744": { "compartment": "compartment_70101", "id": "reaction_10088744", "reactome": "R-BTA-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_73578", "species_29370" ], "modifiers": [ [ "species_10088741", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044396" ] }, "reaction_10089230": { "compartment": "compartment_70101", "id": "reaction_10089230", "reactome": "R-BTA-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10077793": { "compartment": "compartment_70101", "id": "reaction_10077793", "reactome": "R-BTA-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10033541", "catalyst" ] ], "additional_components": [ "species_29926", "F6QEU6", "ENSBTAT00000007589" ] }, "reaction_10088898": { "compartment": "compartment_70101", "id": "reaction_10088898", "reactome": "R-BTA-8959719", "name": "SHPK phosphorylates Sedo to Sedo7P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8959707" ], "products": [ "species_70106", "species_29370", "species_29882" ], "modifiers": [ [ "species_10088895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001095" ] }, "reaction_10073438": { "compartment": "compartment_70101", "id": "reaction_10073438", "reactome": "R-BTA-5661256", "name": "AKR1A1 reduces D-glucuronate to L-gulonate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_5661264", "species_29364" ], "products": [ "species_29366", "species_5661268" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10073431": { "compartment": "compartment_70101", "id": "reaction_10073431", "reactome": "R-BTA-5661240", "name": "DCXR tetramer reduces L-xylulose to xylitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_5660036" ], "products": [ "species_5660033", "species_29366" ], "modifiers": [ [ "species_10073428", "catalyst" ] ], "additional_components": [ "A5PJR3", "ENSBTAT00000085766", "Q1JP75", "ENSBTAT00000085766" ] }, "reaction_10080747": { "compartment": "compartment_70101", "id": "reaction_10080747", "reactome": "R-BTA-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6799540" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10080744", "catalyst" ] ], "additional_components": [ "species_29426", "F1MWT0", "ENSBTAT00000009690" ] }, "reaction_10084129": { "compartment": "compartment_161320", "id": "reaction_10084129", "reactome": "R-BTA-8853686", "name": "MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_8853396" ], "products": [ "species_6799577", "species_6799594" ], "modifiers": [ [ "species_10084126", "catalyst" ] ], "additional_components": [ "Q29451", "ENSBTAT00000070599", "species_29426" ] }, "reaction_10080756": { "compartment": "compartment_161320", "id": "reaction_10080756", "reactome": "R-BTA-6799581", "name": "MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799577", "species_1605715" ], "products": [ "species_6799594", "species_8853719" ], "modifiers": [ [ "species_10080753", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ5", "ENSBTAT00000081381", "species_29426" ] }, "reaction_10067610": { "compartment": "compartment_70101", "id": "reaction_10067610", "reactome": "R-BTA-3322001", "name": "GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067605", "species_29410" ], "products": [ "species_10067607", "species_110096" ], "modifiers": [ [ "species_10067605", "catalyst" ] ], "additional_components": [ "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10067644": { "compartment": "compartment_70101", "id": "reaction_10067644", "reactome": "R-BTA-3322041", "name": "Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067619", "species_29410" ], "products": [ "species_110096", "species_10067641" ], "modifiers": [ [ "species_10067619", "catalyst" ], [ "species_30537", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965" ] }, "reaction_10068748": { "compartment": "compartment_70101", "id": "reaction_10068748", "reactome": "R-BTA-3781018", "name": "EPM2A dimer dephosphorylates phosphoglycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10068745" ], "products": [ "species_10068740", "species_29372" ], "modifiers": [ [ "species_10068745", "catalyst" ] ], "additional_components": [ "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067648": { "compartment": "compartment_70101", "id": "reaction_10067648", "reactome": "R-BTA-3322057", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067641" ], "products": [ "species_10067646" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "ENSBTAT00000083071" ] }, "reaction_10068752": { "compartment": "compartment_70101", "id": "reaction_10068752", "reactome": "R-BTA-3781023", "name": "PPP1R3C binds to glycogen:GYG1:GYS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067627", "species_10068729" ], "products": [ "species_10068750" ], "modifiers": [], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10068755": { "compartment": "compartment_70101", "id": "reaction_10068755", "reactome": "R-BTA-3781024", "name": "GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068750", "species_29410" ], "products": [ "species_109402", "species_10068734" ], "modifiers": [ [ "species_10068750", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423", "Q0VCR4", "ENSBTAT00000019753", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "Q0VCR4", "ENSBTAT00000019753", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067634": { "compartment": "compartment_70101", "id": "reaction_10067634", "reactome": "R-BTA-3322005", "name": "GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067607" ], "products": [ "species_10067627" ], "modifiers": [ [ "species_10067631", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "ENSBTAT00000083071" ] }, "reaction_10067639": { "compartment": "compartment_70101", "id": "reaction_10067639", "reactome": "R-BTA-3322025", "name": "Autoglucosylation of GYG1 complexed with GYS1-a", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067636", "species_29410" ], "products": [ "species_10067605", "species_110096" ], "modifiers": [ [ "species_10067636", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_29926", "A7MB78", "ENSBTAT00000007423" ] }, "reaction_10067622": { "compartment": "compartment_70101", "id": "reaction_10067622", "reactome": "R-BTA-3322003", "name": "Autoglucosylation of GYG1 complexed with GYS1-b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067617", "species_29410" ], "products": [ "species_10067619", "species_110096" ], "modifiers": [ [ "species_10067617", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926", "A7MB78", "ENSBTAT00000007423", "species_29926", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A7MB78", "ENSBTAT00000007423", "species_29926" ] }, "reaction_10090696": { "compartment": "compartment_161320", "id": "reaction_10090696", "reactome": "R-BTA-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_10090685" ], "products": [ "species_1605745", "species_10090689" ], "modifiers": [ [ "species_10090691", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "ENSBTAT00000021325" ] }, "reaction_10034138": { "compartment": "compartment_70101", "id": "reaction_10034138", "reactome": "R-BTA-71593", "name": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034111" ], "products": [ "species_10034135", "species_70113" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10050637": { "compartment": "compartment_70101", "id": "reaction_10050637", "reactome": "R-BTA-453338", "name": "PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050635" ], "products": [ "species_10034078", "species_76577" ], "modifiers": [], "additional_components": [ "species_76577", "F1MJ28", "ENSBTAT00000001373", "F1MJ28", "ENSBTAT00000001373" ] }, "reaction_10034118": { "compartment": "compartment_70101", "id": "reaction_10034118", "reactome": "R-BTA-71552", "name": "limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034099" ], "products": [ "species_10034111" ], "modifiers": [ [ "species_10034115", "catalyst" ] ], "additional_components": [ "A0A3Q1NLJ5", "ENSBTAT00000077965", "species_113527", "A0A3Q1LZJ1", "ENSBTAT00000085404", "species_113527", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LZJ1", "ENSBTAT00000085404", "ENSBTAT00000008518" ] }, "reaction_10033737": { "compartment": "compartment_70101", "id": "reaction_10033737", "reactome": "R-BTA-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29448", "species_29472" ], "products": [ "species_111294", "species_29404", "species_29642", "species_76577" ], "modifiers": [ [ "species_10033734", "catalyst" ] ], "additional_components": [ "Q1LZA3", "ENSBTAT00000079655" ] }, "reaction_10078529": { "compartment": "compartment_70101", "id": "reaction_10078529", "reactome": "R-BTA-6797627", "name": "ASPG hydrolyses L-Asn to L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29642" ], "products": [ "species_29448", "species_29382" ], "modifiers": [ [ "species_10078526", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066927" ] }, "reaction_10033728": { "compartment": "compartment_5460", "id": "reaction_10033728", "reactome": "R-BTA-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113587", "species_113552" ], "modifiers": [ [ "species_10033725", "catalyst" ] ], "additional_components": [ "P12344", "ENSBTAT00000009440" ] }, "reaction_10076130": { "compartment": "compartment_70101", "id": "reaction_10076130", "reactome": "R-BTA-5691507", "name": "ASPA deacetylates NAA to acetate and L-aspartate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5691492" ], "products": [ "species_29416", "species_29448" ], "modifiers": [ [ "species_10076127", "catalyst" ] ], "additional_components": [ "F1MUZ8", "ENSBTAT00000069554", "species_29426" ] }, "reaction_10033716": { "compartment": "compartment_70101", "id": "reaction_10033716", "reactome": "R-BTA-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_76213" ], "products": [ "species_29406", "species_29448" ], "modifiers": [ [ "species_10033713", "catalyst" ] ], "additional_components": [ "P33097", "ENSBTAT00000015873" ] }, "reaction_10076406": { "compartment": "compartment_876", "id": "reaction_10076406", "reactome": "R-BTA-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10076403", "catalyst" ] ], "additional_components": [ "F1MUP1", "ENSBTAT00000009723", "F1MGS8", "ENSBTAT00000000354" ] }, "reaction_10043917": { "compartment": "compartment_70101", "id": "reaction_10043917", "reactome": "R-BTA-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914", "species_76183" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10043914", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019543" ] }, "reaction_10043948": { "compartment": "compartment_70101", "id": "reaction_10043948", "reactome": "R-BTA-209828", "name": "Tryptophan is hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_29500", "species_29368" ], "products": [ "species_71112", "species_209911" ], "modifiers": [ [ "species_10043945", "catalyst" ] ], "additional_components": [ "species_71067", "F1N5Q8", "ENSBTAT00000007030", "E1BGX6", "ENSBTAT00000027708" ] }, "reaction_10033681": { "compartment": "compartment_70101", "id": "reaction_10033681", "reactome": "R-BTA-70523", "name": "PXLP-K314-GPT transaminates L-Ala to form PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_29432" ], "products": [ "species_29404", "species_29398" ], "modifiers": [ [ "species_10033678", "catalyst" ] ], "additional_components": [ "A0A452DIW8", "ENSBTAT00000010309" ] }, "reaction_10091773": { "compartment": "compartment_876", "id": "reaction_10091773", "reactome": "R-BTA-9686930", "name": "RIPK3 is cleaved by CASP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070522" ], "products": [ "species_10091771", "species_10091769" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000024511", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068030": { "compartment": "compartment_70101", "id": "reaction_10068030", "reactome": "R-BTA-3465429", "name": "FLIP(S) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035394", "species_10068026" ], "products": [ "species_10068028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074240": { "compartment": "compartment_70101", "id": "reaction_10074240", "reactome": "R-BTA-5675456", "name": "FLIP(L) and procaspase-8 form heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068034", "species_10068026" ], "products": [ "species_10068032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10074254": { "compartment": "compartment_70101", "id": "reaction_10074254", "reactome": "R-BTA-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052288", "species_10071514" ], "products": [ "species_10074251" ], "modifiers": [ [ "species_10071514", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103", "A0A3Q1MT71", "ENSBTAT00000070103", "Q3SYW8", "ENSBTAT00000034719", "Q3SYW8", "ENSBTAT00000034719", "A0A3Q1MT71", "ENSBTAT00000070103" ] }, "reaction_10091806": { "compartment": "compartment_70101", "id": "reaction_10091806", "reactome": "R-BTA-9688831", "name": "STUB1 ubiquitinates RIPK3 at K55, K363", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091797", "species_10033408" ], "products": [ "species_10091803" ], "modifiers": [ [ "species_10091797", "catalyst" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091793": { "compartment": "compartment_70101", "id": "reaction_10091793", "reactome": "R-BTA-9687828", "name": "O-GlcNAcylation of RIPK3 (TLR4 signaling)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756", "species_10070522" ], "products": [ "species_10091786", "species_110096" ], "modifiers": [ [ "species_10091790", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024511", "ENSBTAT00000024511", "ENSBTAT00000045447" ] }, "reaction_10091808": { "compartment": "compartment_70101", "id": "reaction_10091808", "reactome": "R-BTA-9688832", "name": "MLKL binds PDCD6IP and SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072342", "species_10045220", "species_10067330" ], "products": [ "species_10072344" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023165", "ENSBTAT00000026526", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165" ] }, "reaction_10091779": { "compartment": "compartment_70101", "id": "reaction_10091779", "reactome": "R-BTA-9687625", "name": "ATP binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_10091777" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "species_113592", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10091810": { "compartment": "compartment_70101", "id": "reaction_10091810", "reactome": "R-BTA-9688838", "name": "RIPK3 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091795", "species_10070522" ], "products": [ "species_10091797" ], "modifiers": [], "additional_components": [ "E1B7G3", "ENSBTAT00000025473", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "E1B7G3", "ENSBTAT00000025473" ] }, "reaction_10091783": { "compartment": "compartment_70101", "id": "reaction_10091783", "reactome": "R-BTA-9687638", "name": "MLKL binds IP4, IP5 and IP6 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994146", "species_10070686", "species_1629770", "species_994141" ], "products": [ "species_10091781" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_994141", "species_1629770", "species_994146" ] }, "reaction_10081481": { "compartment": "compartment_161320", "id": "reaction_10081481", "reactome": "R-BTA-6803753", "name": "NAAA hydrolyses NAEs to FAs and ethanolamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605715", "species_6803725" ], "products": [ "species_6803745", "species_6803778" ], "modifiers": [ [ "species_10081478", "catalyst" ] ], "additional_components": [ "CHEBI:71466", "species_5693754", "CHEBI:85299", "CHEBI:85263", "CHEBI:71464", "CHEBI:85262", "species_426576", "species_33549", "species_8934421", "CHEBI:28875", "CHEBI:16196", "species_140356", "F1MN16", "ENSBTAT00000025945" ] }, "reaction_10044540": { "compartment": "compartment_70101", "id": "reaction_10044540", "reactome": "R-BTA-264622", "name": "Cho is acetylated to AcCho by CHAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_76183" ], "products": [ "species_264643", "species_76194" ], "modifiers": [ [ "species_10044537", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022369" ] }, "reaction_10049090": { "compartment": "compartment_876", "id": "reaction_10049090", "reactome": "R-BTA-429594", "name": "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_264638", "species_74113" ], "products": [ "species_264618", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049087", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005693" ] }, "reaction_10071437": { "compartment": "compartment_70101", "id": "reaction_10071437", "reactome": "R-BTA-5336443", "name": "LIN7, CASK and APBA1 bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071423", "species_10071419", "species_10071433" ], "products": [ "species_10071435" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071329", "ENSBTAT00000079326", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "Q32LM6", "ENSBTAT00000070192", "A0A452DHU4", "ENSBTAT00000001914", "A0A3Q1MLH9", "ENSBTAT00000079326", "A0A3Q1LPV4", "ENSBTAT00000071329" ] }, "reaction_10049583": { "compartment": "compartment_70101", "id": "reaction_10049583", "reactome": "R-BTA-444007", "name": "GAT1-3 mediate Na+/Cl- dependent GABA transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352003", "species_74113" ], "products": [ "species_352011", "species_83910", "species_352022" ], "modifiers": [ [ "species_10049580", "catalyst" ] ], "additional_components": [ "A5PJX7", "ENSBTAT00000019308", "E1BPI1", "ENSBTAT00000038826" ] }, "reaction_10052018": { "compartment": "compartment_70101", "id": "reaction_10052018", "reactome": "R-BTA-888592", "name": "Loading of GABA into clathrin sculpted GABA transport vesicle lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352011" ], "products": [ "species_428571" ], "modifiers": [ [ "species_10052015", "catalyst" ] ], "additional_components": [ "ENSBTAT00000063578" ] }, "reaction_10052013": { "compartment": "compartment_917757", "id": "reaction_10052013", "reactome": "R-BTA-888577", "name": "Synthesis of GABA by GAD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10052010", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547", "F1N6X2", "ENSBTAT00000010598" ] }, "reaction_10051999": { "compartment": "compartment_70101", "id": "reaction_10051999", "reactome": "R-BTA-888572", "name": "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_352011", "species_113528" ], "modifiers": [ [ "species_10051996", "catalyst" ] ], "additional_components": [ "Q0VCA1", "ENSBTAT00000009547" ] }, "reaction_10051989": { "compartment": "compartment_5460", "id": "reaction_10051989", "reactome": "R-BTA-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_880046", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113536" ], "modifiers": [ [ "species_10051986", "catalyst" ] ], "additional_components": [ "E1BDP3", "ENSBTAT00000029203" ] }, "reaction_10033755": { "compartment": "compartment_5460", "id": "reaction_10033755", "reactome": "R-BTA-70609", "name": "glutamine + H2O => glutamate + NH4+ [GLS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113522", "species_113521" ], "products": [ "species_113561", "species_113552" ], "modifiers": [ [ "species_10033752", "catalyst" ] ], "additional_components": [ "E1BHZ6", "ENSBTAT00000012233" ] }, "reaction_10044461": { "compartment": "compartment_876", "id": "reaction_10044461", "reactome": "R-BTA-212642", "name": "L-Glutamine transport into neurons", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_212615", "species_74113" ], "products": [ "species_83910", "species_29472" ], "modifiers": [ [ "species_10044458", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014749" ] }, "reaction_10044076": { "compartment": "compartment_984", "id": "reaction_10044076", "reactome": "R-BTA-210404", "name": "SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_210382", "species_29804", "species_74113" ], "products": [ "species_74126", "species_29404", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ], [ "species_10044074", "inhibitor" ] ], "additional_components": [ "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455", "ENSBTAT00000028661" ] }, "reaction_10033746": { "compartment": "compartment_70101", "id": "reaction_10033746", "reactome": "R-BTA-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_31633" ], "products": [ "species_29372", "species_29370", "species_29472" ], "modifiers": [ [ "species_10033743", "catalyst" ] ], "additional_components": [ "P15103", "ENSBTAT00000074216" ] }, "reaction_10044086": { "compartment": "compartment_984", "id": "reaction_10044086", "reactome": "R-BTA-210439", "name": "glutamate uptake by astrocytes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_210382" ], "products": [ "species_29404" ], "modifiers": [ [ "species_10044083", "catalyst" ] ], "additional_components": [] }, "reaction_10054361": { "compartment": "compartment_876", "id": "reaction_10054361", "reactome": "R-BTA-975340", "name": "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054358", "catalyst" ] ], "additional_components": [ "species_428571", "A0A3Q1MA32", "ENSBTAT00000068615", "A0A3Q1MA22", "ENSBTAT00000069238", "F1MHX4", "ENSBTAT00000015688", "Q08E50", "ENSBTAT00000080524", "E1BE96", "ENSBTAT00000017637", "P08219", "ENSBTAT00000009483", "P08220", "ENSBTAT00000023711", "E1BJH4", "ENSBTAT00000060999" ] }, "reaction_10054372": { "compartment": "compartment_876", "id": "reaction_10054372", "reactome": "R-BTA-975449", "name": "GABRR pentamers:GABA transports extracellular Cl- to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10054369", "catalyst" ] ], "additional_components": [ "species_428571", "E1B988", "ENSBTAT00000001857" ] }, "reaction_10051085": { "compartment": "compartment_984", "id": "reaction_10051085", "reactome": "R-BTA-500708", "name": "GRIK3 homomer binds glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050486", "species_210382" ], "products": [ "species_10051083" ], "modifiers": [], "additional_components": [ "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022", "species_210382", "A0A3Q1M9Y0", "ENSBTAT00000073656", "species_352022" ] }, "reaction_10091067": { "compartment": "compartment_70101", "id": "reaction_10091067", "reactome": "R-BTA-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091060", "species_113592" ], "products": [ "species_29370", "species_10091064" ], "modifiers": [ [ "species_10091060", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "E1BIP3", "ENSBTAT00000009431" ] }, "reaction_10091075": { "compartment": "compartment_70101", "id": "reaction_10091075", "reactome": "R-BTA-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091071", "species_10037002" ], "products": [ "species_10091073" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010230", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "F6RXS3", "ENSBTAT00000010230" ] }, "reaction_10090547": { "compartment": "compartment_7660", "id": "reaction_10090547", "reactome": "R-BTA-9029434", "name": "p-S363,S380,T573 RS6K translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090537" ], "products": [ "species_10090545" ], "modifiers": [], "additional_components": [ "A0A3Q1LNQ6", "ENSBTAT00000080174", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1MLN6", "ENSBTAT00000073341", "A0A3Q1LNQ6", "ENSBTAT00000080174" ] }, "reaction_10054318": { "compartment": "compartment_876", "id": "reaction_10054318", "reactome": "R-BTA-975311", "name": "HTR3 pentamers:5HT transport Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10054315", "catalyst" ] ], "additional_components": [ "G3N1Q1", "ENSBTAT00000062928", "F1N4Y2", "ENSBTAT00000014292", "E1BAL4", "ENSBTAT00000056946", "F1N5G0", "ENSBTAT00000055354", "G5E5J6", "ENSBTAT00000022113", "species_209914" ] }, "reaction_10091521": { "compartment": "compartment_876", "id": "reaction_10091521", "reactome": "R-BTA-9648983", "name": "HTR3A pentamer:5HT transports Na+,K+,Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_74112", "species_74113" ], "products": [ "species_29804", "species_83910", "species_74016" ], "modifiers": [ [ "species_10091518", "catalyst" ] ], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10091525": { "compartment": "compartment_876", "id": "reaction_10091525", "reactome": "R-BTA-9649108", "name": "HTR3A pentamer binds 5HT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091523", "species_114523" ], "products": [ "species_10091518" ], "modifiers": [], "additional_components": [ "F1N4Y2", "ENSBTAT00000014292", "F1N4Y2", "ENSBTAT00000014292", "species_209914" ] }, "reaction_10051521": { "compartment": "compartment_70101", "id": "reaction_10051521", "reactome": "R-BTA-629595", "name": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051518", "catalyst" ] ], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051523": { "compartment": "compartment_984", "id": "reaction_10051523", "reactome": "R-BTA-629596", "name": "Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051516", "species_372533" ], "products": [ "species_10051518" ], "modifiers": [], "additional_components": [ "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "F1MDD1", "ENSBTAT00000039651", "F1MF30", "ENSBTAT00000039752", "E1BHK0", "ENSBTAT00000022855", "F1MQ06", "ENSBTAT00000018679", "A0A3Q1MJN8", "ENSBTAT00000075573", "A6QPI7", "ENSBTAT00000020942", "Q8SPU7", "ENSBTAT00000018151", "F1N4T3", "ENSBTAT00000002910", "species_372533" ] }, "reaction_10051498": { "compartment": "compartment_876", "id": "reaction_10051498", "reactome": "R-BTA-622326", "name": "Activation of highly calcium permeable nicotinic acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10051495", "catalyst" ] ], "additional_components": [ "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10051525": { "compartment": "compartment_984", "id": "reaction_10051525", "reactome": "R-BTA-629599", "name": "Binding of acetylcholine to highly calcium permeable acetylcholine receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051493", "species_372533" ], "products": [ "species_10051495" ], "modifiers": [], "additional_components": [ "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679", "species_372533", "F1MF30", "ENSBTAT00000039752", "F1N4T3", "ENSBTAT00000002910", "E1BHK0", "ENSBTAT00000022855", "A0A3Q1MJN8", "ENSBTAT00000075573", "F1MQ06", "ENSBTAT00000018679" ] }, "reaction_10065894": { "compartment": "compartment_876", "id": "reaction_10065894", "reactome": "R-BTA-2559456", "name": "TIRAP binds PIP2-rich regions in the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065890", "species_179856" ], "products": [ "species_10065892" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070781", "species_6810412", "A0A3Q1M4J2", "ENSBTAT00000070781" ] }, "reaction_10039217": { "compartment": "compartment_984", "id": "reaction_10039217", "reactome": "R-BTA-166015", "name": "Association of LBP with LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10039213" ], "products": [ "species_10039215" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_166005" ] }, "reaction_10039560": { "compartment": "compartment_70101", "id": "reaction_10039560", "reactome": "R-BTA-168933", "name": "Dimerization of phosphorylated IRF3/IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039558" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10040197": { "compartment": "compartment_70101", "id": "reaction_10040197", "reactome": "R-BTA-177671", "name": "Dimerized phospho-IRF3/IRF7 is transported to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039558" ], "products": [ "species_10040195" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10085369": { "compartment": "compartment_984", "id": "reaction_10085369", "reactome": "R-BTA-8869683", "name": "oxPL binds LBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2186967", "species_10039213" ], "products": [ "species_10085367" ], "modifiers": [], "additional_components": [ "ENSBTAT00000062921", "G3N2G9", "ENSBTAT00000062921", "species_2186967" ] }, "reaction_10081506": { "compartment": "compartment_984", "id": "reaction_10081506", "reactome": "R-BTA-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081502", "species_181015" ], "products": [ "species_10081504" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_181015", "P10103", "ENSBTAT00000024094" ] }, "reaction_10081510": { "compartment": "compartment_984", "id": "reaction_10081510", "reactome": "R-BTA-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_166005", "species_10081502" ], "products": [ "species_10081508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024094", "species_166005", "P10103", "ENSBTAT00000024094" ] }, "reaction_10060783": { "compartment": "compartment_17957", "id": "reaction_10060783", "reactome": "R-BTA-1678944", "name": "Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060771" ], "products": [ "species_10060769", "species_10060751", "species_211606", "species_10060763" ], "modifiers": [], "additional_components": [ "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592", "Q95M18", "ENSBTAT00000004364", "A0A3Q1MK24", "ENSBTAT00000079344", "ENSBTAT00000074388" ] }, "reaction_10060785": { "compartment": "compartment_17957", "id": "reaction_10060785", "reactome": "R-BTA-1678998", "name": "Endosomal TLRs pass through the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060757" ], "products": [ "species_10060781" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10060773": { "compartment": "compartment_17957", "id": "reaction_10060773", "reactome": "R-BTA-1678923", "name": "TLR folding by chaperones GP96 and CNPY3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060769", "species_211579", "species_10060749", "species_10060763" ], "products": [ "species_10060771" ], "modifiers": [], "additional_components": [ "Q95M18", "ENSBTAT00000004364", "ENSBTAT00000079344", "ENSBTAT00000074388", "A0A3Q1MIF7", "ENSBTAT00000074388", "A0A3Q1MK24", "ENSBTAT00000079344", "Q95M18", "ENSBTAT00000004364", "species_113592" ] }, "reaction_10060759": { "compartment": "compartment_12045", "id": "reaction_10060759", "reactome": "R-BTA-1678921", "name": "Full-length TLR3/7/8/9 binds to UNC93B1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060755", "species_10060751" ], "products": [ "species_10060757" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001581", "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344", "E1BBH4", "ENSBTAT00000001581" ] }, "reaction_10091739": { "compartment": "compartment_70101", "id": "reaction_10091739", "reactome": "R-BTA-9679029", "name": "C-ter TLR7 dimer binds HCQ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091735", "species_9678628" ], "products": [ "species_10091737" ], "modifiers": [], "additional_components": [ "A0A3Q1MK24", "ENSBTAT00000079344", "A0A3Q1MK24", "ENSBTAT00000079344" ] }, "reaction_10066168": { "compartment": "compartment_876", "id": "reaction_10066168", "reactome": "R-BTA-2730900", "name": "Activation of TAK1 complex bound to pUb-TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066165", "species_113592" ], "products": [ "species_10066165", "species_29370" ], "modifiers": [ [ "species_10066165", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "A0A3S5ZPB2", "ENSBTAT00000081933", "E1B7Z0", "ENSBTAT00000077920", "A0A3Q1M7T8", "ENSBTAT00000082809", "A0A3Q1LT51", "ENSBTAT00000068866" ] }, "reaction_10066059": { "compartment": "compartment_70101", "id": "reaction_10066059", "reactome": "R-BTA-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043202", "species_113592" ], "products": [ "species_29370", "species_10066057" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066141": { "compartment": "compartment_876", "id": "reaction_10066141", "reactome": "R-BTA-2730864", "name": "Recruitment of TRAF6 to CBM complex by binding to MALT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066131", "species_10039473" ], "products": [ "species_10066139" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066172": { "compartment": "compartment_876", "id": "reaction_10066172", "reactome": "R-BTA-2730902", "name": "Oligomerization of p-CARMA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066124", "species_10066109" ], "products": [ "species_10066170" ], "modifiers": [], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933" ] }, "reaction_10066127": { "compartment": "compartment_876", "id": "reaction_10066127", "reactome": "R-BTA-2730863", "name": "Phosphorylation of CARMA1 by PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066122", "species_10066057" ], "products": [ "species_29370", "species_10066124" ], "modifiers": [ [ "species_10066057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "species_112275", "E1BMG4", "ENSBTAT00000060978" ] }, "reaction_10066147": { "compartment": "compartment_876", "id": "reaction_10066147", "reactome": "R-BTA-2730882", "name": "Phosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043223", "species_113592" ], "products": [ "species_10043202", "species_29370" ], "modifiers": [ [ "species_10065638", "catalyst" ] ], "additional_components": [ "species_112275", "E1BMG4", "ENSBTAT00000060978", "species_112275", "E1BMG4", "ENSBTAT00000060978", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066180": { "compartment": "compartment_876", "id": "reaction_10066180", "reactome": "R-BTA-2730903", "name": "Oligomerization of TRAF6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039473", "species_10066139" ], "products": [ "species_10066178" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q17QJ6", "ENSBTAT00000018398", "Q3ZCC3", "ENSBTAT00000021630", "species_112275", "E1BMG4", "ENSBTAT00000060978", "Q17QJ6", "ENSBTAT00000018398", "A0A3S5ZPB2", "ENSBTAT00000081933", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10066120": { "compartment": "compartment_876", "id": "reaction_10066120", "reactome": "R-BTA-2730862", "name": "Autophosphorylation of LYN kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066117", "species_113592" ], "products": [ "species_29370", "species_10065617" ], "modifiers": [ [ "species_10066117", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000075171", "ENSBTAT00000075171" ] }, "reaction_10066065": { "compartment": "compartment_876", "id": "reaction_10066065", "reactome": "R-BTA-2730841", "name": "Phosphorylation and activation of VAV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066061" ], "products": [ "species_29370", "species_10066063" ], "modifiers": [ [ "species_179838", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MQP9", "ENSBTAT00000086853" ] }, "reaction_10066082": { "compartment": "compartment_70101", "id": "reaction_10066082", "reactome": "R-BTA-2730844", "name": "Interaction of GRB2:SOS complex with p-SHC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035491", "species_10065484" ], "products": [ "species_10065486" ], "modifiers": [], "additional_components": [ "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "ENSBTAT00000075224", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216" ] }, "reaction_10066151": { "compartment": "compartment_876", "id": "reaction_10066151", "reactome": "R-BTA-2730886", "name": "Phosphorylation of SHC by SYK kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066149", "species_113592" ], "products": [ "species_29370", "species_10065484" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075224", "ENSBTAT00000075224", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066080": { "compartment": "compartment_876", "id": "reaction_10066080", "reactome": "R-BTA-2730842", "name": "PI3K associates with phosphorylated GAB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035523", "species_10066076" ], "products": [ "species_10066078" ], "modifiers": [], "additional_components": [ "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10066144": { "compartment": "compartment_876", "id": "reaction_10066144", "reactome": "R-BTA-2730870", "name": "Phosphorylation of PIP2 to PIP3 by PI3K", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10066078", "catalyst" ] ], "additional_components": [ "A0A3Q1M864", "ENSBTAT00000084533", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "species_179838", "P32871", "ENSBTAT00000072391", "F1MYM3", "ENSBTAT00000009083", "P23726", "ENSBTAT00000003033" ] }, "reaction_10065642": { "compartment": "compartment_876", "id": "reaction_10065642", "reactome": "R-BTA-2454240", "name": "Recruitment of SYK to p-FCERI gamma subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065638", "species_10037584" ], "products": [ "species_10065640" ], "modifiers": [], "additional_components": [ "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066094": { "compartment": "compartment_70101", "id": "reaction_10066094", "reactome": "R-BTA-2730847", "name": "Hydrolysis of PIP2 by PLCG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10066091", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MYF9", "ENSBTAT00000023383", "E1BKA6", "ENSBTAT00000020161", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10066052": { "compartment": "compartment_876", "id": "reaction_10066052", "reactome": "R-BTA-2730833", "name": "Phosphorylation of TEC kinases by p-SYK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066042" ], "products": [ "species_29370", "species_10066047" ], "modifiers": [ [ "species_10066049", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "species_179838", "F1MSH3", "ENSBTAT00000046704", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MHG9", "ENSBTAT00000075168", "G3N342", "ENSBTAT00000065204", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "F1N261", "ENSBTAT00000075171", "E1BNU1", "ENSBTAT00000026773", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10066102": { "compartment": "compartment_876", "id": "reaction_10066102", "reactome": "R-BTA-2730858", "name": "Autophosphorylation of BTK/ITK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10066047" ], "products": [ "species_10066099", "species_29370" ], "modifiers": [ [ "species_10066047", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838", "A0A3Q1MQP9", "ENSBTAT00000086853", "Q0IIE2", "ENSBTAT00000075224", "F1N7C3", "ENSBTAT00000015471", "Q3T0F9", "ENSBTAT00000006216", "E1BKA6", "ENSBTAT00000020161", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MSH3", "ENSBTAT00000046704", "species_179838" ] }, "reaction_10081085": { "compartment": "compartment_6800424", "id": "reaction_10081085", "reactome": "R-BTA-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081071" ], "products": [ "species_10081083" ], "modifiers": [], "additional_components": [ "A0A3Q1LQX2", "ENSBTAT00000078403", "Q05204", "ENSBTAT00000045121", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1N8P4", "ENSBTAT00000066443", "F1MAU4", "ENSBTAT00000047906", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MS24", "ENSBTAT00000075240", "P61285", "ENSBTAT00000081563", "A7YWC4", "ENSBTAT00000012676", "P61585", "ENSBTAT00000005600", "G3N3S2", "ENSBTAT00000064122", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3S5ZPJ1", "ENSBTAT00000017459", "F1MIW8", "ENSBTAT00000018382", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M893", "ENSBTAT00000074148", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1LWC4", "ENSBTAT00000077476", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "F6PZJ9", "ENSBTAT00000084844", "E1BAJ4", "ENSBTAT00000013713", "Q9BDR7", "ENSBTAT00000034054", "A2VDP5", "ENSBTAT00000004547", "A2VDL2", "ENSBTAT00000042889", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "E1B6Z4", "ENSBTAT00000026429", "E1BHT5", "ENSBTAT00000020277", "A5PJK0", "ENSBTAT00000001458", "G5E5S0", "ENSBTAT00000028846", "Q1RMS1", "ENSBTAT00000000367", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1LMZ3", "ENSBTAT00000069125", "A0JN39", "ENSBTAT00000008616", "E1B876", "ENSBTAT00000047448", "Q3LUH2", "ENSBTAT00000032346", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "E1BDF5", "ENSBTAT00000049662", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A7YWC4", "ENSBTAT00000012676", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "Q05204", "ENSBTAT00000045121", "A0JN39", "ENSBTAT00000008616", "A0A3Q1LMZ3", "ENSBTAT00000069125", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MS24", "ENSBTAT00000075240", "A5PJK0", "ENSBTAT00000001458", "Q1RMS1", "ENSBTAT00000000367", "E1B876", "ENSBTAT00000047448", "A2VDP5", "ENSBTAT00000004547", "E1BD53", "ENSBTAT00000035679", "A0A3S5ZPJ1", "ENSBTAT00000017459", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1LUD9", "ENSBTAT00000083004", "A0A3Q1LWC4", "ENSBTAT00000077476", "P61585", "ENSBTAT00000005600", "F1MHU6", "ENSBTAT00000020198", "A0A3Q1N8P4", "ENSBTAT00000066443", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BCF4", "ENSBTAT00000012484", "E1BDF5", "ENSBTAT00000049662", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "F6PZJ9", "ENSBTAT00000084844", "Q9BDR7", "ENSBTAT00000034054", "F1MIW8", "ENSBTAT00000018382", "Q9MYM4", "ENSBTAT00000021325", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1M893", "ENSBTAT00000074148", "F1MAU4", "ENSBTAT00000047906", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "E1BGJ5", "ENSBTAT00000005511" ] }, "reaction_10079949": { "compartment": "compartment_1462052", "id": "reaction_10079949", "reactome": "R-BTA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079839" ], "products": [ "species_10079947" ], "modifiers": [], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A452DI43", "ENSBTAT00000008107", "F1MRP0", "ENSBTAT00000000876", "Q5E987", "ENSBTAT00000027507", "Q0II59", "ENSBTAT00000024203", "P68401", "ENSBTAT00000007398", "Q3SZ62", "ENSBTAT00000032937", "Q3ZCI9", "ENSBTAT00000018917", "P28782", "ENSBTAT00000066555", "E1BI70", "ENSBTAT00000027682", "P79105", "ENSBTAT00000063314", "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MFC3", "ENSBTAT00000069599", "A5PKG9", "ENSBTAT00000078914", "Q3T0A3", "ENSBTAT00000063284", "P12763", "ENSBTAT00000000673", "F6QEU6", "ENSBTAT00000007589", "A1A4J1", "ENSBTAT00000056305", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "P10103", "ENSBTAT00000024094", "Q17QP9", "ENSBTAT00000046166", "F1MWU9", "ENSBTAT00000057500", "Q2KJ46", "ENSBTAT00000028608", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F1MHT1", "ENSBTAT00000008518", "Q5E9F9", "ENSBTAT00000065774", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q2KJ25", "ENSBTAT00000003145", "A0A452DJA8", "ENSBTAT00000016346", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A140T8A5", "ENSBTAT00000027348", "A6QQL9", "ENSBTAT00000019085", "F1MWE0", "ENSBTAT00000028983", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "P62935", "ENSBTAT00000015924", "A0A452DIT4", "ENSBTAT00000023325", "Q58DK5", "ENSBTAT00000000315", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1LXA9", "ENSBTAT00000077815", "G3MXC8", "ENSBTAT00000064442", "A0A452DIE3", "ENSBTAT00000000841", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "F1MWE0", "ENSBTAT00000028983", "Q5E9F9", "ENSBTAT00000065774", "Q2KJ25", "ENSBTAT00000003145", "Q3ZCI9", "ENSBTAT00000018917", "F1MRP0", "ENSBTAT00000000876", "Q0II59", "ENSBTAT00000024203", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "P28782", "ENSBTAT00000066555", "P79105", "ENSBTAT00000063314", "A0A3Q1MFC3", "ENSBTAT00000069599", "P68401", "ENSBTAT00000007398", "A5PKG9", "ENSBTAT00000078914", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "A0A452DIE3", "ENSBTAT00000000841", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3Q1LXA9", "ENSBTAT00000077815", "A7MBA7", "ENSBTAT00000013758", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "P12763", "ENSBTAT00000000673", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "F1MHT1", "ENSBTAT00000008518", "Q2KJ46", "ENSBTAT00000028608", "Q17QP9", "ENSBTAT00000046166" ] }, "reaction_10080063": { "compartment": "compartment_6799371", "id": "reaction_10080063", "reactome": "R-BTA-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080039" ], "products": [ "species_10080061" ], "modifiers": [], "additional_components": [ "A0A3Q1LRA9", "ENSBTAT00000080425", "G3MWP1", "ENSBTAT00000064480", "P33046", "ENSBTAT00000044788", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1BPI3", "ENSBTAT00000026661", "Q3ZCL0", "ENSBTAT00000076131", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1N9Y5", "ENSBTAT00000085713", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q2LGB5", "ENSBTAT00000010835", "E1BCU6", "ENSBTAT00000027423", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "A0A3Q1M2J3", "ENSBTAT00000079464", "Q5GN72", "ENSBTAT00000022991", "E1B8Y2", "ENSBTAP00000001395", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZC41", "ENSBTAT00000024335", "F6RMV5", "ENSBTAT00000003618", "G3N0J0", "ENSBTAT00000063400", "E1B6Z6", "ENSBTAT00000018806", "F1MVJ8", "ENSBTAT00000030920", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "E1BFV0", "ENSBTAT00000008650", "P24627", "ENSBTAT00000001704", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F1MRP0", "ENSBTAT00000000876", "A0A3Q1LWX5", "ENSBTAT00000081739", "P80189", "ENSBTAT00000038266", "A0A3Q1MD51", "ENSBTAT00000087110", "F1MW13", "ENSBTAT00000009806", "Q3MHQ1", "ENSBTAT00000007133", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "G3MWP1", "ENSBTAT00000064480", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "A4IF76", "ENSBTAT00000074688", "E1BPI3", "ENSBTAT00000026661", "Q3MHQ1", "ENSBTAT00000007133", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0II59", "ENSBTAT00000024203", "A6QLB1", "ENSBTAT00000016464", "Q0VCN9", "ENSBTAT00000027602", "F1MRP0", "ENSBTAT00000000876", "Q2LGB5", "ENSBTAT00000010835", "A7YWG4", "ENSBTAT00000009917", "A0A3Q1LRA9", "ENSBTAT00000080425", "E1B6Z6", "ENSBTAT00000018806", "F6RMV5", "ENSBTAT00000003618", "Q2KJ64", "ENSBTAT00000016461", "A0A3Q1M2R9", "ENSBTAT00000085538", "F1MW13", "ENSBTAT00000009806", "Q3ZCL0", "ENSBTAT00000076131", "A0A3Q1LWX5", "ENSBTAT00000081739", "E1B8Y2", "ENSBTAP00000001395", "E1BFV0", "ENSBTAT00000008650", "Q3ZC41", "ENSBTAT00000024335", "P24627", "ENSBTAT00000001704", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10080719": { "compartment": "compartment_6799351", "id": "reaction_10080719", "reactome": "R-BTA-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080687" ], "products": [ "species_10080717" ], "modifiers": [], "additional_components": [ "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MIE9", "ENSBTAT00000079230", "A2VDL2", "ENSBTAT00000042889", "Q29455", "ENSBTAT00000070817", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1MP64", "ENSBTAT00000068539", "Q0VD15", "ENSBTAT00000018402", "A0A3Q1M0A2", "ENSBTAT00000074088", "A0A3Q1LNV7", "ENSBTAT00000083870", "A6H797", "ENSBTAT00000026715", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MFT3", "ENSBTAT00000084806", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BFE2", "ENSBTAT00000020345", "F1N1F5", "ENSBTAT00000021843", "O46521", "ENSBTAT00000067849", "Q58DM3", "ENSBTAT00000008479", "E1BNL9", "ENSBTAT00000027255", "E1BHT5", "ENSBTAT00000020277", "F1N4H1", "ENSBTAT00000055016", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1MIW3", "ENSBTAT00000037423", "P26201", "ENSBTAT00000080828", "A0A3Q1M6K1", "ENSBTAT00000081330", "A0A3Q1MED5", "ENSBTAT00000085048", "P62833", "ENSBTAT00000068678", "F1ME65", "ENSBTAT00000015804", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1M4C7", "ENSBTAT00000078122", "A8E4P3", "ENSBTAT00000052503", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NF89", "ENSBTAT00000076616", "F1MTY9", "ENSBTAT00000047056", "F1MN89", "ENSBTAT00000008168", "F1N680", "ENSBTAT00000026019", "F1MLP3", "ENSBTAT00000008097", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1MQ27", "ENSBTAT00000069303", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q1JPA0", "ENSBTAT00000076578", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "Q32PA1", "ENSBTAT00000002967", "F1N3R7", "ENSBTAT00000026770", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1M288", "ENSBTAT00000085751", "Q6QRN7", "ENSBTAT00000005137", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "P62833", "ENSBTAT00000068678", "Q6QRN7", "ENSBTAT00000005137", "A6H797", "ENSBTAT00000026715", "A0A3Q1M0A2", "ENSBTAT00000074088", "A8E4P3", "ENSBTAT00000052503", "A0A3Q1MSR2", "ENSBTAT00000075634", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1NF89", "ENSBTAT00000076616", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "F1ME65", "ENSBTAT00000015804", "F1N1F5", "ENSBTAT00000021843", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "Q0VD15", "ENSBTAT00000018402", "Q58DM3", "ENSBTAT00000008479", "Q29455", "ENSBTAT00000070817", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "F1N680", "ENSBTAT00000026019", "Q2KI97", "ENSBTAT00000020710", "F1MIW3", "ENSBTAT00000037423", "F1N3R7", "ENSBTAT00000026770", "F1MLP3", "ENSBTAT00000008097", "F1N4H1", "ENSBTAT00000055016", "F1MZS9", "ENSBTAT00000035230", "P26201", "ENSBTAT00000080828", "F1MTY9", "ENSBTAT00000047056", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1MN89", "ENSBTAT00000008168", "A0A3Q1M2M7", "ENSBTAT00000073921", "A0A3Q1M4C7", "ENSBTAT00000078122", "F1N3T5", "ENSBTAT00000021761", "A0A3Q1M6K1", "ENSBTAT00000081330", "Q17QQ1", "ENSBTAT00000047833", "O46521", "ENSBTAT00000067849", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1MIE9", "ENSBTAT00000079230", "Q1JPA0", "ENSBTAT00000076578", "E1BHT5", "ENSBTAT00000020277", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "A4IFF5", "ENSBTAT00000026308", "A0A3Q1M288", "ENSBTAT00000085751", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10079391": { "compartment": "compartment_6800173", "id": "reaction_10079391", "reactome": "R-BTA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079319" ], "products": [ "species_10079389" ], "modifiers": [], "additional_components": [ "A7YWG4", "ENSBTAT00000009917", "Q0VCN9", "ENSBTAT00000027602", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A3Q1LMG1", "ENSBTAT00000083687", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5W1C4", "ENSBTAT00000080090", "Q5GN72", "ENSBTAT00000022991", "F1MVJ8", "ENSBTAT00000030920", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "G3N0J0", "ENSBTAT00000063400", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A140T831", "ENSBTAT00000000683", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A3Q1M739", "ENSBTAT00000077529", "A0A452DIT4", "ENSBTAT00000023325", "E1B8Y2", "ENSBTAP00000001395", "A7YWU9", "ENSBTAT00000028731", "P25326", "ENSBTAT00000022774", "P24627", "ENSBTAT00000001704", "E1BCU6", "ENSBTAT00000027423", "P01035", "ENSBTAT00000000790", "A0A3Q1N9Y5", "ENSBTAT00000085713", "P33046", "ENSBTAT00000044788", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1LNC8", "ENSBTAT00000066559", "Q3ZBE7", "ENSBTAT00000032525", "P80189", "ENSBTAT00000038266", "A0A140T8A5", "ENSBTAT00000027348", "A4IF76", "ENSBTAT00000074688", "Q5EA55", "ENSBTAT00000069302", "Q3ZCL0", "ENSBTAT00000076131", "P02070", "ENSBTAT00000057323", "A0A3Q1M2R9", "ENSBTAT00000085538", "Q5EA55", "ENSBTAT00000069302", "A7YWU9", "ENSBTAT00000028731", "A0A3Q1MU93", "ENSBTAT00000086688", "P01888", "ENSBTAT00000016359", "A0A140T8A5", "ENSBTAT00000027348", "Q5W1C4", "ENSBTAT00000080090", "Q3MHK8", "ENSBTAT00000034879", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3S5ZPB0", "ENSBTAT00000017416", "A0A3Q1MD51", "ENSBTAT00000087110", "Q5GN72", "ENSBTAT00000022991", "E1BCU6", "ENSBTAT00000027423", "P33046", "ENSBTAT00000044788", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "P80189", "ENSBTAT00000038266", "G3N0J0", "ENSBTAT00000063400", "A0A3Q1LNC8", "ENSBTAT00000066559", "P25326", "ENSBTAT00000022774", "A0A452DIT4", "ENSBTAT00000023325", "A4IF76", "ENSBTAT00000074688", "A0A3Q1MGS0", "ENSBTAT00000074118", "P01035", "ENSBTAT00000000790", "A0A140T831", "ENSBTAT00000000683", "F1MD23", "ENSBTAT00000045994", "O46675", "ENSBTAT00000039536", "Q0VCN9", "ENSBTAT00000027602", "A7YWG4", "ENSBTAT00000009917", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2R9", "ENSBTAT00000085538", "E1B8Y2", "ENSBTAP00000001395", "Q3ZCL0", "ENSBTAT00000076131", "P24627", "ENSBTAT00000001704", "P02070", "ENSBTAT00000057323", "A0A3Q1M739", "ENSBTAT00000077529", "Q3ZBE7", "ENSBTAT00000032525", "A0A3Q1N9Y5", "ENSBTAT00000085713", "F1MVJ8", "ENSBTAT00000030920" ] }, "reaction_10079199": { "compartment": "compartment_876", "id": "reaction_10079199", "reactome": "R-BTA-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079131" ], "products": [ "species_10079197" ], "modifiers": [], "additional_components": [ "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1NF89", "ENSBTAT00000076616", "Q0VD15", "ENSBTAT00000018402", "Q9TTY5", "ENSBTAT00000038757", "A0JN39", "ENSBTAT00000008616", "A0A452DIB1", "ENSBTAT00000013018", "P08037", "ENSBTAT00000020286", "F1MDR7", "ENSBTAT00000003865", "A6QLS9", "ENSBTAT00000001303", "E1BK38", "ENSBTAT00000061018", "E1BCF4", "ENSBTAT00000012484", "P11023", "ENSBTAT00000014062", "A0A3Q1MS24", "ENSBTAT00000075240", "Q08DC2", "ENSBTAT00000075871", "A7YWC4", "ENSBTAT00000012676", "F1MNI4", "ENSBTAT00000018777", "F6PZJ9", "ENSBTAT00000084844", "F1MCK4", "ENSBTAT00000054453", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1LZT3", "ENSBTAT00000069265", "Q673L2", "ENSBTAT00000027807", "Q2KI99", "ENSBTAT00000071484", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A2VDL2", "ENSBTAT00000042889", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1MHJ9", "ENSBTAT00000086833", "E1BI37", "ENSBTAT00000035878", "Q3LUH2", "ENSBTAT00000032346", "F1MHH9", "ENSBTAT00000029116", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1M0R0", "ENSBTAT00000081916", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1LUD9", "ENSBTAT00000083004", "Q2KII9", "ENSBTAT00000019566", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N0T3", "ENSBTAT00000023242", "E1BPL8", "ENSBTAT00000002681", "E1B876", "ENSBTAT00000047448", "P61585", "ENSBTAT00000005600", "E1BD53", "ENSBTAT00000035679", "Q1RMI2", "ENSBTAT00000000453", "F1MIE6", "ENSBTAT00000037678", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1MB09", "ENSBTAT00000068383", "A5PJK0", "ENSBTAT00000001458", "E1BGJ5", "ENSBTAT00000005511", "Q1JPA0", "ENSBTAT00000076578", "F1MTR1", "ENSBTAT00000001190", "F1MHH9", "ENSBTAT00000029116", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A6QLS9", "ENSBTAT00000001303", "F1MTR1", "ENSBTAT00000001190", "Q0VCB4", "ENSBTAT00000026403", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "Q673L2", "ENSBTAT00000027807", "F1MCK4", "ENSBTAT00000054453", "F6PZJ9", "ENSBTAT00000084844", "P11023", "ENSBTAT00000014062", "Q08DC2", "ENSBTAT00000075871", "A0A452DIB1", "ENSBTAT00000013018", "E1BPL8", "ENSBTAT00000002681", "A0A3Q1NF89", "ENSBTAT00000076616", "Q3SZA1", "ENSBTAT00000046161", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1MNI4", "ENSBTAT00000018777", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1MB09", "ENSBTAT00000068383", "A0A3Q1NNM6", "ENSBTAT00000081334", "A7YWC4", "ENSBTAT00000012676", "Q0VD15", "ENSBTAT00000018402", "A0JN39", "ENSBTAT00000008616", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "Q3LUH2", "ENSBTAT00000032346", "Q2KII9", "ENSBTAT00000019566", "F1MJS9", "ENSBTAT00000013320", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1MS24", "ENSBTAT00000075240", "Q1RMI2", "ENSBTAT00000000453", "E1BI37", "ENSBTAT00000035878", "A5PJK0", "ENSBTAT00000001458", "E1B876", "ENSBTAT00000047448", "E1BD53", "ENSBTAT00000035679", "A0A3Q1LUD9", "ENSBTAT00000083004", "E1BK38", "ENSBTAT00000061018", "P61585", "ENSBTAT00000005600", "Q2KI99", "ENSBTAT00000071484", "A6QLZ0", "ENSBTAT00000043753", "A0A3Q1LQX2", "ENSBTAT00000078403", "E1BCF4", "ENSBTAT00000012484", "F1MIE6", "ENSBTAT00000037678", "A0A3Q1M0R0", "ENSBTAT00000081916", "P08037", "ENSBTAT00000020286", "Q1JPA0", "ENSBTAT00000076578", "G3X6D0", "ENSBTAT00000004058", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10078929": { "compartment": "compartment_6798757", "id": "reaction_10078929", "reactome": "R-BTA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078881" ], "products": [ "species_10078927" ], "modifiers": [], "additional_components": [ "A0A3Q1MCZ8", "ENSBTAT00000067584", "P61223", "ENSBTAT00000019575", "Q2KIW2", "ENSBTAT00000000146", "Q02827", "ENSBTAT00000024209", "Q9MYM4", "ENSBTAT00000021325", "A0A3Q1MDC6", "ENSBTAT00000075241", "F1N3T5", "ENSBTAT00000021761", "A8E4P3", "ENSBTAT00000052503", "F1MAU4", "ENSBTAT00000047906", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1N0X5", "ENSBTAT00000068372", "E1BK38", "ENSBTAT00000061018", "Q3T0Y8", "ENSBTAT00000033040", "G3MY77", "ENSBTAT00000065645", "F1MDR7", "ENSBTAT00000003865", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q29455", "ENSBTAT00000070817", "A4IFF5", "ENSBTAT00000026308", "F1ME65", "ENSBTAT00000015804", "A0A3Q1MAL1", "ENSBTAT00000070277", "F1N680", "ENSBTAT00000026019", "A5PJY9", "ENSBTAT00000020644", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1NHB1", "ENSBTAT00000080189", "Q05204", "ENSBTAT00000045121", "A0A3Q1N8P4", "ENSBTAT00000066443", "Q0II86", "ENSBTAT00000027666", "Q9XSK2", "ENSBTAT00000015829", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "E1BI37", "ENSBTAT00000035878", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "P08037", "ENSBTAT00000020286", "A0A3Q1MDS4", "ENSBTAT00000073232", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q3T0Y8", "ENSBTAT00000033040", "F1MAU4", "ENSBTAT00000047906", "F1ME65", "ENSBTAT00000015804", "Q9MYM4", "ENSBTAT00000021325", "P61223", "ENSBTAT00000019575", "A0A3Q1N0X5", "ENSBTAT00000068372", "A0A3Q1MDC6", "ENSBTAT00000075241", "A8E4P3", "ENSBTAT00000052503", "P08037", "ENSBTAT00000020286", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1MCZ8", "ENSBTAT00000067584", "A0A3Q1LRW6", "ENSBTAT00000080603", "A0A3Q1MD45", "ENSBTAT00000080813", "A0A3Q1MG36", "ENSBTAT00000082227", "A0A3Q1MIV3", "ENSBTAT00000081596", "A0A3Q1MUW6", "ENSBTAT00000080813", "F1MZQ5", "ENSBTAT00000035878", "F1N4Y5", "ENSBTAT00000021451", "E1BI37", "ENSBTAT00000035878", "Q2KIW2", "ENSBTAT00000000146", "A0A3Q1NHB1", "ENSBTAT00000080189", "F1N3T5", "ENSBTAT00000021761", "E1BCF4", "ENSBTAT00000012484", "A0A3Q1MAL1", "ENSBTAT00000070277", "A0A3Q1N8P4", "ENSBTAT00000066443", "G3MY77", "ENSBTAT00000065645", "Q9XSK2", "ENSBTAT00000015829", "E1BK38", "ENSBTAT00000061018", "A4IFF5", "ENSBTAT00000026308", "Q02827", "ENSBTAT00000024209", "A0A3Q1MDS4", "ENSBTAT00000073232", "Q0II86", "ENSBTAT00000027666", "F1N680", "ENSBTAT00000026019", "F1MDR7", "ENSBTAT00000003865", "Q29455", "ENSBTAT00000070817", "Q3T0Q9", "ENSBTAT00000015396", "A0A3Q1MAZ1", "ENSBTAT00000071382", "Q05204", "ENSBTAT00000045121", "F1MTK4", "ENSBTAT00000001250", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10081265": { "compartment": "compartment_984", "id": "reaction_10081265", "reactome": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081245" ], "products": [ "species_10081263" ], "modifiers": [], "additional_components": [ "A0A3Q1LTT9", "ENSBTAT00000073013", "Q5E9F9", "ENSBTAT00000065774", "Q3SWY3", "ENSBTAT00000025179", "F1MWE0", "ENSBTAT00000028983", "Q3SZ62", "ENSBTAT00000032937", "F1MHT1", "ENSBTAT00000008518", "A0A452DI43", "ENSBTAT00000008107", "F1MNS8", "ENSBTAT00000061310", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "Q2KJ46", "ENSBTAT00000028608", "Q3T0A3", "ENSBTAT00000063284", "A0A140T8A5", "ENSBTAT00000027348", "P34955", "ENSBTAT00000072441", "P02070", "ENSBTAT00000057323", "Q5W1C4", "ENSBTAT00000080090", "Q3ZBE7", "ENSBTAT00000032525", "P68401", "ENSBTAT00000007398", "A1A4J1", "ENSBTAT00000056305", "Q3ZCI9", "ENSBTAT00000018917", "E1BFV0", "ENSBTAT00000008650", "G3N0V2", "ENSBTAT00000065029", "F6RMV5", "ENSBTAT00000003618", "A0A3Q1M2J3", "ENSBTAT00000079464", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1LMG1", "ENSBTAT00000083687", "A0A3S5ZPB0", "ENSBTAT00000017416", "Q5I2E5", "ENSBTAT00000084171", "Q29RY7", "ENSBTAT00000012815", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "A0A3Q1MD51", "ENSBTAT00000087110", "A0A452DJA8", "ENSBTAT00000016346", "A6QQL9", "ENSBTAT00000019085", "P10103", "ENSBTAT00000024094", "F1MWU9", "ENSBTAT00000057500", "Q27975", "ENSBTAT00000017500", "P01035", "ENSBTAT00000000790", "P62935", "ENSBTAT00000015924", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "Q58DK5", "ENSBTAT00000000315", "A5D984", "ENSBTAT00000047412", "A0A3Q1MGS0", "ENSBTAT00000074118", "A0A140T831", "ENSBTAT00000000683", "A0A452DIT4", "ENSBTAT00000023325", "Q3SYU2", "ENSBTAT00000005581", "P68103", "ENSBTAT00000087016", "A0A3Q1N1A3", "ENSBTAT00000073135", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "Q2KJ25", "ENSBTAT00000003145", "Q17QP9", "ENSBTAT00000046166", "A4IFQ6", "ENSBTAT00000018403", "P07688", "ENSBTAT00000036795", "P25326", "ENSBTAT00000022774", "E1BB52", "ENSBTAT00000002003", "A0A3Q1LXA9", "ENSBTAT00000077815", "A0A452DJ01", "ENSBTAT00000011678", "G3MXC8", "ENSBTAT00000064442", "A0A3Q1LPS7", "ENSBTAT00000084564", "E1BA23", "ENSBTAT00000021018", "F1MMD5", "ENSBTAT00000008020", "F1MXZ0", "ENSBTAT00000023218", "A3KMY8", "ENSBTAT00000000941", "A6QLZ3", "ENSBTAT00000010988", "A0A3Q1M5Y2", "ENSBTAT00000084883", "Q2KJ25", "ENSBTAT00000003145", "F6RMV5", "ENSBTAT00000003618", "Q3ZCI9", "ENSBTAT00000018917", "A0A140T831", "ENSBTAT00000000683", "G3MXC8", "ENSBTAT00000064442", "P01035", "ENSBTAT00000000790", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1MGS0", "ENSBTAT00000074118", "A6QLZ3", "ENSBTAT00000010988", "P68401", "ENSBTAT00000007398", "A3KMY8", "ENSBTAT00000000941", "A0A3Q1M2J3", "ENSBTAT00000079464", "F1MNS8", "ENSBTAT00000061310", "A0A140T8A5", "ENSBTAT00000027348", "A0A3Q1LMV5", "ENSBTAT00000084460", "F6QEU6", "ENSBTAT00000007589", "Q5I2E5", "ENSBTAT00000084171", "Q3SYU2", "ENSBTAT00000005581", "A0A452DJA8", "ENSBTAT00000016346", "P10103", "ENSBTAT00000024094", "E1BFV0", "ENSBTAT00000008650", "F1MWU9", "ENSBTAT00000057500", "A0A3Q1NLJ5", "ENSBTAT00000077965", "A0A3Q1LTT9", "ENSBTAT00000073013", "Q3SWY3", "ENSBTAT00000025179", "Q3SZ62", "ENSBTAT00000032937", "A0A452DI43", "ENSBTAT00000008107", "Q5E987", "ENSBTAT00000027507", "A0A3Q1LX83", "ENSBTAT00000001309", "Q3T0Y5", "ENSBTAT00000001309", "A0A3Q1M5Y2", "ENSBTAT00000084883", "F1MMD5", "ENSBTAT00000008020", "E1BA23", "ENSBTAT00000021018", "Q3T0A3", "ENSBTAT00000063284", "A0A452DIT4", "ENSBTAT00000023325", "A0A3Q1LPS7", "ENSBTAT00000084564", "P34955", "ENSBTAT00000072441", "P25326", "ENSBTAT00000022774", "A7MBJ5", "ENSBTAT00000013112", "Q2HJ57", "ENSBTAT00000021704", "A0A3Q1LMG1", "ENSBTAT00000083687", "F1MUL1", "ENSBTAT00000034356", "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "A0A3Q1LXA9", "ENSBTAT00000077815", "Q58DK5", "ENSBTAT00000000315", "A0A3Q1MD51", "ENSBTAT00000087110", "A5D984", "ENSBTAT00000047412", "A0A3S5ZPB0", "ENSBTAT00000017416", "P62935", "ENSBTAT00000015924", "P68103", "ENSBTAT00000087016", "A0A3Q1N4Z1", "ENSBTAT00000073135", "A0A3Q1NLY8", "ENSBTAT00000073135", "A0A3Q1N1A3", "ENSBTAT00000073135", "Q5W1C4", "ENSBTAT00000080090", "Q29RY7", "ENSBTAT00000012815", "Q5E9F9", "ENSBTAT00000065774", "Q27975", "ENSBTAT00000017500", "F1MWE0", "ENSBTAT00000028983", "G3N0V2", "ENSBTAT00000065029", "A6QQL9", "ENSBTAT00000019085", "A1A4J1", "ENSBTAT00000056305", "A0A452DJ01", "ENSBTAT00000011678", "F1MHT1", "ENSBTAT00000008518", "P02070", "ENSBTAT00000057323", "A4IFQ6", "ENSBTAT00000018403", "Q2KJ46", "ENSBTAT00000028608", "Q3ZBE7", "ENSBTAT00000032525", "P07688", "ENSBTAT00000036795", "Q17QP9", "ENSBTAT00000046166", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10080435": { "compartment": "compartment_1470028", "id": "reaction_10080435", "reactome": "R-BTA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080307" ], "products": [ "species_10080433" ], "modifiers": [], "additional_components": [ "A0A3Q1MNB1", "ENSBTAT00000080327", "A0A3Q1MPF1", "ENSBTAT00000080327", "F1MGY9", "ENSBTAT00000022716", "A0A3Q1MPJ7", "ENSBTAT00000067144", "H7BWW2", "ENSBTAT00000048411", "F1MU84", "ENSBTAT00000006001", "A7MBA2", "ENSBTAT00000006754", "A6QPT4", "ENSBTAT00000067752", "O77834", "ENSBTAT00000006383", "E1BI70", "ENSBTAT00000027682", "P80189", "ENSBTAT00000038266", "A0A3Q1LYV0", "ENSBTAT00000070714", "Q5GN72", "ENSBTAT00000022991", "A6QLB7", "ENSBTAT00000017775", "G3MWP1", "ENSBTAT00000064480", "F1MXZ0", "ENSBTAT00000023218", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A3Q1MRR6", "ENSBTAT00000078659", "A7YWU9", "ENSBTAT00000028731", "Q3MHM5", "ENSBTAT00000074704", "Q17QI1", "ENSBTAT00000065281", "A0A3Q1LUG9", "ENSBTAT00000076880", "E1BPI3", "ENSBTAT00000026661", "O46415", "ENSBTAT00000009965", "Q2LGB5", "ENSBTAT00000010835", "F1N7I6", "ENSBTAT00000024550", "F1N1V6", "ENSBTAT00000005121", "F1MU24", "ENSBTAT00000006069", "Q2KJD0", "ENSBTAT00000009158", "A0A3Q1LQA6", "ENSBTAT00000072426", "E1BFP1", "ENSBTAT00000000304", "A7YWG4", "ENSBTAT00000009917", "Q29451", "ENSBTAT00000070599", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "E1BI28", "ENSBTAT00000029099", "E1BAD2", "ENSBTAT00000054741", "A0A452DJ87", "ENSBTAT00000039203", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1ML33", "ENSBTAT00000073654", "A0A3Q1LMW6", "ENSBTAT00000073103", "E1B8B5", "ENSBTAT00000053165", "A0A3Q1LTS9", "ENSBTAT00000068563", "F1MMS7", "ENSBTAT00000065330", "A0A3Q1LY36", "ENSBTAT00000068245", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LIW8", "ENSBTAT00000073870", "Q3ZCI9", "ENSBTAT00000018917", "P79345", "ENSBTAT00000029271", "F6QH17", "ENSBTAT00000026526", "F1MUP9", "ENSBTAT00000009715", "F1MGC2", "ENSBTAT00000036230", "G3N2H4", "ENSBTAT00000063121", "F6QIT9", "ENSBTAT00000019270", "A3KMY8", "ENSBTAT00000000941", "P04272", "ENSBTAT00000012655", "A0A3Q1MS42", "ENSBTAT00000074408", "Q2KJ64", "ENSBTAT00000016461", "F1N048", "ENSBTAT00000004411", "A6QLZ3", "ENSBTAT00000010988", "E1B725", "ENSBTAT00000025636", "Q2KIM0", "ENSBTAT00000042970", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "F1N5H2", "ENSBTAT00000002297", "G3MXK8", "ENSBTAT00000064845", "A6QQ81", "ENSBTAT00000034528", "A0A3Q1LYV0", "ENSBTAT00000070714", "F1MXZ0", "ENSBTAT00000023218", "E1BI70", "ENSBTAT00000027682", "A0A3Q1MPF1", "ENSBTAT00000080327", "A0A3Q1MNB1", "ENSBTAT00000080327", "F1MU84", "ENSBTAT00000006001", "F1MGY9", "ENSBTAT00000022716", "A6QLZ3", "ENSBTAT00000010988", "P04272", "ENSBTAT00000012655", "F1N5H2", "ENSBTAT00000002297", "E1BAD2", "ENSBTAT00000054741", "H7BWW2", "ENSBTAT00000048411", "A3KMY8", "ENSBTAT00000000941", "G3N2H4", "ENSBTAT00000063121", "E1BI28", "ENSBTAT00000029099", "A0A452DJ87", "ENSBTAT00000039203", "A0A3Q1MPJ7", "ENSBTAT00000067144", "A6QNX2", "ENSBTAT00000064726", "A0A3Q1NEU9", "ENSBTAT00000066561", "A0A3Q1LUG9", "ENSBTAT00000076880", "F6QH17", "ENSBTAT00000026526", "A0A0A0MPA0", "ENSBTAT00000038516", "A0A3Q1MGZ6", "ENSBTAT00000077453", "A0A452DJK6", "ENSBTAT00000064935", "C4PU73", "ENSBTAT00000009718", "G3N1U4", "ENSBTAT00000064475", "A0A0A0MP89", "ENSBTAT00000009261", "A0A0A0MP92", "ENSBTAT00000011576", "F1MUP9", "ENSBTAT00000009715", "A0A3Q1ML33", "ENSBTAT00000073654", "E1B8B5", "ENSBTAT00000053165", "F1MMS7", "ENSBTAT00000065330", "G3X8C3", "ENSBTAT00000055709", "A0A3Q1LKA9", "ENSBTAT00000084208", "A0A3Q1LMW6", "ENSBTAT00000073103", "A0A3Q1LTS9", "ENSBTAT00000068563", "A0A3Q1LY36", "ENSBTAT00000068245", "F1N1V6", "ENSBTAT00000005121", "Q3MHM5", "ENSBTAT00000074704", "Q2KJD0", "ENSBTAT00000009158", "Q17QI1", "ENSBTAT00000065281", "Q2KJ64", "ENSBTAT00000016461", "A7MBA2", "ENSBTAT00000006754", "O77834", "ENSBTAT00000006383", "Q2LGB5", "ENSBTAT00000010835", "Q2KIM0", "ENSBTAT00000042970", "A7YWU9", "ENSBTAT00000028731", "E1B725", "ENSBTAT00000025636", "A6QLB7", "ENSBTAT00000017775", "E1BPI3", "ENSBTAT00000026661", "A0A3Q1M5Y2", "ENSBTAT00000084883", "A0A3Q1MRR6", "ENSBTAT00000078659", "A0A3Q1LFK5", "ENSBTAT00000071669", "Q3ZBH5", "ENSBTAT00000013796", "A0A3Q1N5S3", "ENSBTAT00000084634", "F6QIT9", "ENSBTAT00000019270", "F1N048", "ENSBTAT00000004411", "P80189", "ENSBTAT00000038266", "A0A3Q1MS42", "ENSBTAT00000074408", "G3MWP1", "ENSBTAT00000064480", "Q5GN72", "ENSBTAT00000022991", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "Q29451", "ENSBTAT00000070599", "Q3ZCI9", "ENSBTAT00000018917", "A7YWG4", "ENSBTAT00000009917", "A6QPT4", "ENSBTAT00000067752", "F1MU24", "ENSBTAT00000006069", "F1N7I6", "ENSBTAT00000024550", "E1BFP1", "ENSBTAT00000000304", "A0A3Q1LQA6", "ENSBTAT00000072426", "A0A3Q1LIW8", "ENSBTAT00000073870", "F1MGC2", "ENSBTAT00000036230", "P79345", "ENSBTAT00000029271", "O46415", "ENSBTAT00000009965" ] }, "reaction_10079653": { "compartment": "compartment_6799713", "id": "reaction_10079653", "reactome": "R-BTA-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10079613" ], "products": [ "species_10079651" ], "modifiers": [], "additional_components": [ "A0A3Q1MIE9", "ENSBTAT00000079230", "F1N0T3", "ENSBTAT00000023242", "E1BFE2", "ENSBTAT00000020345", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "G3MZR7", "ENSBTAT00000064604", "A0A3Q1MHX4", "ENSBTAT00000081728", "E1B8E5", "ENSBTAT00000052760", "Q9TTY5", "ENSBTAT00000038757", "Q58DM3", "ENSBTAT00000008479", "A0A3Q1MP64", "ENSBTAT00000068539", "A0A3Q1LNV7", "ENSBTAT00000083870", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "O46521", "ENSBTAT00000067849", "A8E4P3", "ENSBTAT00000052503", "P61285", "ENSBTAT00000081563", "Q2KI97", "ENSBTAT00000020710", "A0A3Q1MED5", "ENSBTAT00000085048", "G5E5S0", "ENSBTAT00000028846", "A0A3Q1NDL5", "ENSBTAT00000086325", "A0A3Q1LL92", "ENSBTAT00000066802", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1NNM6", "ENSBTAT00000081334", "E1B6Z4", "ENSBTAT00000026429", "G5E5N4", "ENSBTAT00000026431", "Q9MYM4", "ENSBTAT00000021325", "Q32LK2", "ENSBTAT00000022077", "A0A3Q1M893", "ENSBTAT00000074148", "A0A3Q1LPW8", "ENSBTAT00000075991", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A4IFU2", "ENSBTAT00000083623", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "A0JN39", "ENSBTAT00000008616", "A2VDL2", "ENSBTAT00000042889", "G3X6D0", "ENSBTAT00000004058", "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A5D7R9", "ENSBTAT00000012897", "Q3ZBG1", "ENSBTAT00000023671", "A0A3Q1MFP5", "ENSBTAT00000068010", "F1N4H1", "ENSBTAT00000055016", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1M2M7", "ENSBTAT00000073921", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MQ27", "ENSBTAT00000069303", "Q32PA1", "ENSBTAT00000002967", "G3N3S2", "ENSBTAT00000064122", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "A0A3Q1ML46", "ENSBTAT00000071567", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1LZT3", "ENSBTAT00000069265", "E1BHT5", "ENSBTAT00000020277", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1M288", "ENSBTAT00000085751", "F1MHU6", "ENSBTAT00000020198", "F1MMX5", "ENSBTAT00000069044", "A0A3Q1MFP5", "ENSBTAT00000068010", "E1BFU3", "ENSBTAT00000040027", "A0A3Q1ML46", "ENSBTAT00000071567", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P61285", "ENSBTAT00000081563", "A8E4P3", "ENSBTAT00000052503", "Q9BDR7", "ENSBTAT00000034054", "Q9MYM4", "ENSBTAT00000021325", "E1BNL9", "ENSBTAT00000027255", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MED5", "ENSBTAT00000085048", "A0A3Q1M893", "ENSBTAT00000074148", "Q3T0Y8", "ENSBTAT00000033040", "E1BGJ5", "ENSBTAT00000005511", "A0A3Q1NNM6", "ENSBTAT00000081334", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0JN39", "ENSBTAT00000008616", "Q58DM3", "ENSBTAT00000008479", "Q3LUH2", "ENSBTAT00000032346", "Q9TTY5", "ENSBTAT00000038757", "F1N0T3", "ENSBTAT00000023242", "A0A3Q1LZT3", "ENSBTAT00000069265", "A0A3Q1MHX4", "ENSBTAT00000081728", "G3MZR7", "ENSBTAT00000064604", "E1B8E5", "ENSBTAT00000052760", "E1BKZ8", "ENSBTAT00000011656", "F1MST2", "ENSBTAT00000031802", "Q2KI97", "ENSBTAT00000020710", "G3N3S2", "ENSBTAT00000064122", "F1N4H1", "ENSBTAT00000055016", "A0A3Q1M2M7", "ENSBTAT00000073921", "Q3ZBG1", "ENSBTAT00000023671", "A5D7R9", "ENSBTAT00000012897", "O46521", "ENSBTAT00000067849", "Q17QQ1", "ENSBTAT00000047833", "Q3T132", "ENSBTAT00000048084", "A0A3Q1MFT3", "ENSBTAT00000084806", "A0A3Q1LPW8", "ENSBTAT00000075991", "A4IFU2", "ENSBTAT00000083623", "Q32LK2", "ENSBTAT00000022077", "G5E5S0", "ENSBTAT00000028846", "E1BFE2", "ENSBTAT00000020345", "A0A3Q1LNV7", "ENSBTAT00000083870", "E1B6Z4", "ENSBTAT00000026429", "A0A3Q1LL92", "ENSBTAT00000066802", "G5E5N4", "ENSBTAT00000026431", "A0A3Q1LVA6", "ENSBTAT00000066593", "A0A3Q1MIE9", "ENSBTAT00000079230", "E1BHT5", "ENSBTAT00000020277", "G3X6D0", "ENSBTAT00000004058", "E1BAJ4", "ENSBTAT00000013713", "A0A3Q1NDL5", "ENSBTAT00000086325", "Q32PA1", "ENSBTAT00000002967", "A0A3Q1LN32", "ENSBTAT00000084846", "A0A3Q1LWA7", "ENSBTAT00000084846", "E1BNM1", "ENSBTAT00000084846", "G3MXU0", "ENSBTAT00000084657", "G5E574", "ENSBTAT00000084846", "G5E671", "ENSBTAT00000084846", "A0A3Q1N1V7", "ENSBTAT00000084846", "A0A3Q1NNA9", "ENSBTAT00000084846", "A0A3Q1NNG7", "ENSBTAT00000084846", "E1BFM6", "ENSBTAT00000084846", "A0A3Q1M1J2", "ENSBTAT00000074686", "A0A3Q1M411", "ENSBTAT00000084846", "A0A3Q1M953", "ENSBTAT00000084846", "A0A3Q1MX09", "ENSBTAT00000084846", "A0A3Q1MP64", "ENSBTAT00000068539", "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10072392": { "compartment": "compartment_876", "id": "reaction_10072392", "reactome": "R-BTA-5621366", "name": "SYK binds to p-Y65,Y76-FCER1G", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072358", "species_10037584" ], "products": [ "species_10072390" ], "modifiers": [], "additional_components": [ "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000075168", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10072395": { "compartment": "compartment_876", "id": "reaction_10072395", "reactome": "R-BTA-5621370", "name": "SYK autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072390", "species_113592" ], "products": [ "species_29370", "species_10072360" ], "modifiers": [ [ "species_10072390", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054" ] }, "reaction_10084636": { "compartment": "compartment_876", "id": "reaction_10084636", "reactome": "R-BTA-8858500", "name": "CLEC10A binds Tn-MUC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084632", "species_10084616" ], "products": [ "species_10084634" ], "modifiers": [], "additional_components": [ "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897", "ENSBTAT00000054378", "E1BJL5", "ENSBTAT00000054378", "A0A3Q1M633", "ENSBTAT00000072582", "A0A3Q1LQ52", "ENSBTAT00000085382", "A0A3Q1M2T0", "ENSBTAT00000083797", "A0A3Q1M6U9", "ENSBTAT00000075287", "A0A3Q1LPY0", "ENSBTAT00000066675", "A0A3Q1N072", "ENSBTAT00000071114", "G5E5A7", "ENSBTAT00000010897" ] }, "reaction_10072364": { "compartment": "compartment_876", "id": "reaction_10072364", "reactome": "R-BTA-5621347", "name": "PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072362" ], "products": [ "species_10072360", "species_10072008" ], "modifiers": [], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "ENSBTAT00000074574" ] }, "reaction_10072383": { "compartment": "compartment_876", "id": "reaction_10072383", "reactome": "R-BTA-5621355", "name": "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072378" ], "products": [ "species_10072358", "species_29370" ], "modifiers": [ [ "species_10072380", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "Q3LUH2", "ENSBTAT00000032346", "CHEBI:28808", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10072388": { "compartment": "compartment_876", "id": "reaction_10072388", "reactome": "R-BTA-5621363", "name": "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072385" ], "products": [ "species_29370", "species_10072362" ], "modifiers": [ [ "species_10072385", "catalyst" ] ], "additional_components": [ "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574", "A0A3Q1MHG9", "ENSBTAT00000075168", "CHEBI:28808", "Q3LUH2", "ENSBTAT00000032346", "Q9BDR7", "ENSBTAT00000034054", "A0A3Q1MMD9", "ENSBTAT00000074574" ] }, "reaction_10072374": { "compartment": "compartment_876", "id": "reaction_10072374", "reactome": "R-BTA-5621353", "name": "CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072370", "species_5621138" ], "products": [ "species_10072372" ], "modifiers": [], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016", "species_5621138", "Q9BDR7", "ENSBTAT00000034054", "F1N4H1", "ENSBTAT00000055016" ] }, "reaction_10072057": { "compartment": "compartment_876", "id": "reaction_10072057", "reactome": "R-BTA-5607753", "name": "CARD9 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072055", "species_10071996" ], "products": [ "species_10071998" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072011": { "compartment": "compartment_876", "id": "reaction_10072011", "reactome": "R-BTA-5607735", "name": "p-Y753,Y759-PLCG2 hydrolyses PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10072008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10072045": { "compartment": "compartment_876", "id": "reaction_10072045", "reactome": "R-BTA-5607750", "name": "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072038", "species_113592" ], "products": [ "species_29370", "species_10072043" ], "modifiers": [ [ "species_10040307", "catalyst" ] ], "additional_components": [ "CHEBI:37671", "F1N2F3", "ENSBTAT00000085840", "F1N2F3", "ENSBTAT00000085840", "CHEBI:37671", "ENSBTAT00000011767" ] }, "reaction_10072061": { "compartment": "compartment_876", "id": "reaction_10072061", "reactome": "R-BTA-5607755", "name": "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072059" ], "products": [ "species_10072008" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10072015": { "compartment": "compartment_876", "id": "reaction_10072015", "reactome": "R-BTA-5607737", "name": "BCL10 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072000", "species_10043291" ], "products": [ "species_10072013" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072032": { "compartment": "compartment_876", "id": "reaction_10072032", "reactome": "R-BTA-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072004" ], "products": [ "species_10072019" ], "modifiers": [], "additional_components": [ "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072002": { "compartment": "compartment_876", "id": "reaction_10072002", "reactome": "R-BTA-5607733", "name": "BCL10 binds CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071998", "species_10043291" ], "products": [ "species_10072000" ], "modifiers": [], "additional_components": [ "A0A3Q1LKU2", "ENSBTAT00000074019", "ENSBTAT00000018398", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019" ] }, "reaction_10072053": { "compartment": "compartment_876", "id": "reaction_10072053", "reactome": "R-BTA-5607751", "name": "TRAF6 oligomerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072049", "species_10039473" ], "products": [ "species_10072051" ], "modifiers": [], "additional_components": [ "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630", "ENSBTAT00000021630", "Q17QJ6", "ENSBTAT00000018398", "A0A3Q1LKU2", "ENSBTAT00000074019", "Q3ZCC3", "ENSBTAT00000021630" ] }, "reaction_10072006": { "compartment": "compartment_876", "id": "reaction_10072006", "reactome": "R-BTA-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070610", "species_112275" ], "products": [ "species_10072004" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078659", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10072022": { "compartment": "compartment_876", "id": "reaction_10072022", "reactome": "R-BTA-5607740", "name": "PKC-delta phosphorylates CARD9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10072017" ], "products": [ "species_29370", "species_10071996" ], "modifiers": [ [ "species_10072019", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074019", "ENSBTAT00000074019", "species_112275", "A0A3Q1MRR6", "ENSBTAT00000078659" ] }, "reaction_10054649": { "compartment": "compartment_876", "id": "reaction_10054649", "reactome": "R-BTA-977602", "name": "Complement factor I binds to MCP, CR1:C4b, C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054645", "species_10054492" ], "products": [ "species_10054647" ], "modifiers": [], "additional_components": [ "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10054494": { "compartment": "compartment_984", "id": "reaction_10054494", "reactome": "R-BTA-976801", "name": "Complement factor I complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054490", "species_10054488" ], "products": [ "species_10054492" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076236", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236" ] }, "reaction_10066238": { "compartment": "compartment_984", "id": "reaction_10066238", "reactome": "R-BTA-2855047", "name": "Hydrolysis of internal thioester in C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10039322" ], "products": [ "species_10066236" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019" ] }, "reaction_10090400": { "compartment": "compartment_984", "id": "reaction_10090400", "reactome": "R-BTA-9021306", "name": "C1-Inh binds and inactivates C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084018" ], "products": [ "species_10084063" ], "modifiers": [], "additional_components": [ "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "E1BMJ0", "ENSBTAT00000021638", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10055971": { "compartment": "compartment_876", "id": "reaction_10055971", "reactome": "R-BTA-1006169", "name": "Factor H binds host cell surface markers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1006146", "species_10054484" ], "products": [ "species_10055969" ], "modifiers": [], "additional_components": [ "CHEBI:24505", "species_1006168", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "A0A3Q1LSC6", "ENSBTAT00000069343", "F1MC45", "ENSBTAT00000029340", "CHEBI:24505", "species_1006168" ] }, "reaction_10087797": { "compartment": "compartment_876", "id": "reaction_10087797", "reactome": "R-BTA-8951486", "name": "CD46 binds C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054643", "species_10054624" ], "products": [ "species_10054645" ], "modifiers": [], "additional_components": [ "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "ENSBTAT00000073079", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10084020": { "compartment": "compartment_984", "id": "reaction_10084020", "reactome": "R-BTA-8852266", "name": "C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039462", "species_10038209" ], "products": [ "species_10084018" ], "modifiers": [], "additional_components": [ "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "ENSBTAT00000021638", "E1BMJ0", "ENSBTAT00000021638", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10054678": { "compartment": "compartment_876", "id": "reaction_10054678", "reactome": "R-BTA-977615", "name": "Factor I inactivates MCP/CR1-bound C4b/C3b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054647" ], "products": [ "species_10054675", "species_10054624", "species_10054657", "species_10054492" ], "modifiers": [ [ "species_10054647", "catalyst" ] ], "additional_components": [ "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "ENSBTAT00000073079", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1MF14", "ENSBTAT00000076236", "A0A3Q1N570", "ENSBTAT00000073079", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10039465": { "compartment": "compartment_984", "id": "reaction_10039465", "reactome": "R-BTA-166753", "name": "Conversion of C4 into C4a and C4b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039302" ], "products": [ "species_10039310", "species_10039322" ], "modifiers": [ [ "species_10039462", "catalyst" ] ], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935" ] }, "reaction_10039778": { "compartment": "compartment_984", "id": "reaction_10039778", "reactome": "R-BTA-173626", "name": "Activation of C1r", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039759" ], "products": [ "species_10039765" ], "modifiers": [ [ "species_10039759", "catalyst" ], [ "species_10039776", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "species_74016", "C4T8B4", "ENSBTAT00000018469", "species_1524071", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146" ] }, "reaction_10039782": { "compartment": "compartment_876", "id": "reaction_10039782", "reactome": "R-BTA-173631", "name": "Activation of C1s", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039765" ], "products": [ "species_10039462" ], "modifiers": [ [ "species_10039765", "catalyst" ] ], "additional_components": [ "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "A0A3Q1MGP1", "ENSBTAT00000073935", "A0A3Q1MGP1", "ENSBTAT00000073935", "Q2KIV9", "ENSBTAT00000014871", "A0A3B0IZF8", "ENSBTAT00000014865", "Q5E9E3", "ENSBTAT00000040146", "G3N0V0", "ENSBTAT00000066155", "A0A3Q1M0K3", "ENSBTAT00000085031", "A0A3Q1M458", "ENSBTAT00000085031", "A0A3Q1M667", "ENSBTAT00000085031", "A0A3Q1MFI7", "ENSBTAT00000081783", "A0A3Q1LKV0", "ENSBTAT00000085031", "A0A3Q1LLT0", "ENSBTAT00000085031", "G3N188", "ENSBTAT00000085031", "G3N1H5", "ENSBTAT00000064325", "G3N3Q3", "ENSBTAT00000085031", "A0A3Q1MI29", "ENSBTAT00000085031", "A0A3Q1ML26", "ENSBTAT00000085031", "G3MXG6", "ENSBTAT00000085031", "G3N148", "ENSBTAT00000085031" ] }, "reaction_10054736": { "compartment": "compartment_876", "id": "reaction_10054736", "reactome": "R-BTA-981713", "name": "C4b binds to cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039322", "species_983438" ], "products": [ "species_10054643" ], "modifiers": [], "additional_components": [ "F1MVK1", "ENSBTAT00000045468", "E1BH06", "ENSBTAT00000009019", "E1BH06", "ENSBTAT00000009019", "F1MVK1", "ENSBTAT00000045468" ] }, "reaction_10053134": { "compartment": "compartment_17906", "id": "reaction_10053134", "reactome": "R-BTA-936564", "name": "NLRX1 inhibits MAVS-DDX58 interaction.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10053130" ], "products": [ "species_10053132" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000016601", "F1MUU5", "ENSBTAT00000016601", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10053122": { "compartment": "compartment_70101", "id": "reaction_10053122", "reactome": "R-BTA-936563", "name": "ISGylation of DDX58", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053104", "species_10053118" ], "products": [ "species_10053120" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061377", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "O02741", "ENSBTAT00000019573", "A0A452DII5", "ENSBTAT00000017267", "A0A3Q1LPN8", "ENSBTAT00000083455", "F1MKU1", "ENSBTAT00000061377" ] }, "reaction_10053095": { "compartment": "compartment_7660", "id": "reaction_10053095", "reactome": "R-BTA-936380", "name": "Interaction of PIN1 with p-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053091", "species_10053086" ], "products": [ "species_10053093" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056088": { "compartment": "compartment_7660", "id": "reaction_10056088", "reactome": "R-BTA-1028820", "name": "Formation of VAF (virus-activated factor) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056080", "species_10053054" ], "products": [ "species_10056086" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10053058": { "compartment": "compartment_7660", "id": "reaction_10053058", "reactome": "R-BTA-933536", "name": "p-IRF7 dimer interacts with coactivator CBP/p300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040193", "species_10053054" ], "products": [ "species_10053056" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10092318": { "compartment": "compartment_17906", "id": "reaction_10092318", "reactome": "R-BTA-9709842", "name": "MAVS binds TOMM70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053126", "species_10070254" ], "products": [ "species_10092316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085261", "ENSBTAT00000019001", "Q08E34", "ENSBTAT00000019001", "A0A3Q1MIH6", "ENSBTAT00000085261" ] }, "reaction_10056090": { "compartment": "compartment_70101", "id": "reaction_10056090", "reactome": "R-BTA-1028821", "name": "Dimerization of Phospho IRF3 or phospho IRF7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039552" ], "products": [ "species_10039556", "species_10039554", "species_10056078" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10056082": { "compartment": "compartment_13231", "id": "reaction_10056082", "reactome": "R-BTA-1028816", "name": "Translocation of phosphorylated IRF3,IRF7 dimers into nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556", "species_10039554", "species_10056078" ], "products": [ "species_10056080", "species_10040193", "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869", "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10056084": { "compartment": "compartment_7660", "id": "reaction_10056084", "reactome": "R-BTA-1028817", "name": "CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053054", "species_10040189" ], "products": [ "species_10056076" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092", "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "E1B8D6", "ENSBTAT00000021556", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10066559": { "compartment": "compartment_70101", "id": "reaction_10066559", "reactome": "R-BTA-3134962", "name": "DHX36 binds DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066555", "species_3134861" ], "products": [ "species_10066557" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008082", "Q05B79", "ENSBTAT00000008082" ] }, "reaction_10090837": { "compartment": "compartment_13231", "id": "reaction_10090837", "reactome": "R-BTA-9604487", "name": "p-IRF7:p-IRF7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039554" ], "products": [ "species_10040193" ], "modifiers": [], "additional_components": [ "A0A3Q1MWF9", "ENSBTAT00000075628", "A0A3Q1MWF9", "ENSBTAT00000075628" ] }, "reaction_10066536": { "compartment": "compartment_70101", "id": "reaction_10066536", "reactome": "R-BTA-3134804", "name": "STING ubiquitination by TRIM32 or TRIM56", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10061500" ], "products": [ "species_10066530", "species_10055114" ], "modifiers": [ [ "species_10061500", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801", "ENSBTAT00000071484", "ENSBTAT00000022801", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10061502": { "compartment": "compartment_70101", "id": "reaction_10061502", "reactome": "R-BTA-1964496", "name": "STING binds TRIM32 or TRIM56 ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055114", "species_10061498" ], "products": [ "species_10061500" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022801", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "Q0VCP5", "ENSBTAT00000022801" ] }, "reaction_10066551": { "compartment": "compartment_70101", "id": "reaction_10066551", "reactome": "R-BTA-3134946", "name": "DDX41 ubiquitination by TRIM21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054900", "species_10033408", "species_10066540" ], "products": [ "species_10066548" ], "modifiers": [ [ "species_10054900", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018459", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "Q7YRV4", "ENSBTAT00000018459", "ENSBTAT00000018459" ] }, "reaction_10066608": { "compartment": "compartment_70101", "id": "reaction_10066608", "reactome": "R-BTA-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10066604" ], "products": [ "species_10066606" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "E1BIN9", "ENSBTAT00000011748", "species_874088" ] }, "reaction_10065388": { "compartment": "compartment_70101", "id": "reaction_10065388", "reactome": "R-BTA-2395992", "name": "p-T,4S-IRF3 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039546" ], "products": [ "species_10039556" ], "modifiers": [], "additional_components": [ "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10063376": { "compartment": "compartment_70101", "id": "reaction_10063376", "reactome": "R-BTA-2032396", "name": "Dimerized phospho-IRF3 migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039556" ], "products": [ "species_10040189" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869" ] }, "reaction_10067225": { "compartment": "compartment_70101", "id": "reaction_10067225", "reactome": "R-BTA-3249372", "name": "p-S407,Y641-STAT6 is dimerized", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067208" ], "products": [ "species_10067210" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067229": { "compartment": "compartment_70101", "id": "reaction_10067229", "reactome": "R-BTA-3249378", "name": "STING recruits TBK1 and STAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053189", "species_10046560", "species_10065393" ], "products": [ "species_10067227" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067231": { "compartment": "compartment_70101", "id": "reaction_10067231", "reactome": "R-BTA-3249379", "name": "p-S407-STAT6 is phosphorylated at Tyr641", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067220", "species_113592" ], "products": [ "species_29370", "species_10067208" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008311", "ENSBTAT00000008311" ] }, "reaction_10067233": { "compartment": "compartment_70101", "id": "reaction_10067233", "reactome": "R-BTA-3249390", "name": "TBK1 is phosphorylated within STING:TBK1:STAT6 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10067227" ], "products": [ "species_10067218", "species_29370" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10067216": { "compartment": "compartment_70101", "id": "reaction_10067216", "reactome": "R-BTA-3249370", "name": "p-S407,Y641-STAT6 dimer migrates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067210" ], "products": [ "species_10067214" ], "modifiers": [], "additional_components": [ "F1MGJ4", "ENSBTAT00000008311", "F1MGJ4", "ENSBTAT00000008311" ] }, "reaction_10067223": { "compartment": "compartment_70101", "id": "reaction_10067223", "reactome": "R-BTA-3249371", "name": "TBK1 phosphorylates STAT6 at Ser407", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067218", "species_113592" ], "products": [ "species_10067220", "species_29370", "species_10065404" ], "modifiers": [ [ "species_10067218", "catalyst" ] ], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000008311", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "F1MGJ4", "ENSBTAT00000008311", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065402": { "compartment": "compartment_70101", "id": "reaction_10065402", "reactome": "R-BTA-2396002", "name": "TBK1 is phosphorylated within STING:TBK1:IRF3 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065395", "species_113592" ], "products": [ "species_29370", "species_10065400" ], "modifiers": [], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10065407": { "compartment": "compartment_70101", "id": "reaction_10065407", "reactome": "R-BTA-2396007", "name": "IRF3 is phosphorylated by TBK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065400" ], "products": [ "species_29370", "species_10065404", "species_10039546" ], "modifiers": [ [ "species_10065400", "catalyst" ] ], "additional_components": [ "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134", "ENSBTAT00000031869", "Q4JF28", "ENSBTAT00000031869", "Q2KI99", "ENSBTAT00000071484", "E1BKP4", "ENSBTAT00000023134" ] }, "reaction_10066880": { "compartment": "compartment_12045", "id": "reaction_10066880", "reactome": "R-BTA-3244643", "name": "STING binds cyclic GMP-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3244587", "species_10065409" ], "products": [ "species_10066878" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "species_3244587" ] }, "reaction_10090019": { "compartment": "compartment_70101", "id": "reaction_10090019", "reactome": "R-BTA-9013869", "name": "DDX41 binds bacterial c-di-AMP, c-di-GMP ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8982080", "species_10066540" ], "products": [ "species_10090017" ], "modifiers": [], "additional_components": [ "species_2395973", "CHEBI:47037", "ENSBTAT00000043510", "A3KN07", "ENSBTAT00000043510", "species_2395973", "CHEBI:47037" ] }, "reaction_10065413": { "compartment": "compartment_12045", "id": "reaction_10065413", "reactome": "R-BTA-2396009", "name": "STING binds c-di-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065409", "species_2395973" ], "products": [ "species_10065411" ], "modifiers": [], "additional_components": [ "Q2KI99", "ENSBTAT00000071484", "species_2395973", "Q2KI99", "ENSBTAT00000071484" ] }, "reaction_10066532": { "compartment": "compartment_12045", "id": "reaction_10066532", "reactome": "R-BTA-3134800", "name": "STING dimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061498" ], "products": [ "species_10065409" ], "modifiers": [ [ "species_10066530", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071484", "Q2KI99", "ENSBTAT00000071484", "ENSBTAT00000071484" ] }, "reaction_10081432": { "compartment": "compartment_984", "id": "reaction_10081432", "reactome": "R-BTA-6803063", "name": "RNASEs bind bacterial LPS, PGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_6803074" ], "products": [ "species_10081430" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "CHEBI:55478", "species_6789198", "species_166005", "CHEBI:55478", "species_6789198", "species_166005", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10082008": { "compartment": "compartment_984", "id": "reaction_10082008", "reactome": "R-BTA-6807565", "name": "GNLY is transferred to the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939" ], "products": [ "species_10082006" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "ENSBTAT00000083501" ] }, "reaction_10056539": { "compartment": "compartment_984", "id": "reaction_10056539", "reactome": "R-BTA-1222685", "name": "Cathelicidin LL-37 binds to bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056535", "species_8879165" ], "products": [ "species_10056537" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044788", "P33046", "ENSBTAT00000044788" ] }, "reaction_10082012": { "compartment": "compartment_1222282", "id": "reaction_10082012", "reactome": "R-BTA-6807578", "name": "GNLY binds the bacterial cell surface in the phagosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082006", "species_8931784" ], "products": [ "species_10082010" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10083100": { "compartment": "compartment_984", "id": "reaction_10083100", "reactome": "R-BTA-6813626", "name": "LEAP2 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083096", "species_8931784" ], "products": [ "species_10083098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025186", "species_1462049", "species_1462049", "Q95JC3", "ENSBTAT00000025186" ] }, "reaction_10070906": { "compartment": "compartment_984", "id": "reaction_10070906", "reactome": "R-BTA-5229273", "name": "LCN2:2,5DHBA binds Fe3+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070902", "species_912516" ], "products": [ "species_10070904" ], "modifiers": [], "additional_components": [ "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806", "species_917966", "CHEBI:17189", "E1B6Z6", "ENSBTAT00000018806" ] }, "reaction_10056416": { "compartment": "compartment_1222282", "id": "reaction_10056416", "reactome": "R-BTA-1222491", "name": "Lactoferrin scavenges iron ions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2101051", "species_10056412", "species_1222611" ], "products": [ "species_10056414" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001704", "species_917966", "P24627", "ENSBTAT00000001704", "species_2101051" ] }, "reaction_10078759": { "compartment": "compartment_984", "id": "reaction_10078759", "reactome": "R-BTA-6798489", "name": "S100A7 or S100A7A binds Zn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078755", "species_158417" ], "products": [ "species_10078757" ], "modifiers": [], "additional_components": [ "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838", "species_29426", "species_74016", "A0A3Q1LGT8", "ENSBTAT00000083141", "E1BKA1", "ENSBTAT00000046857", "Q28050", "ENSBTAT00000010838" ] }, "reaction_10082004": { "compartment": "compartment_984", "id": "reaction_10082004", "reactome": "R-BTA-6807144", "name": "HTN1,HTN3 or HTN5 binds the bacterial anionic surface ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081994", "species_8931784" ], "products": [ "species_10082002" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077381", "species_1462049", "species_1462049", "A0A3Q1LX31", "ENSBTAT00000077381" ] }, "reaction_10081559": { "compartment": "compartment_984", "id": "reaction_10081559", "reactome": "R-BTA-6804527", "name": "INTL1 binds bacterial glycans", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081555", "species_6804535" ], "products": [ "species_10081557" ], "modifiers": [], "additional_components": [ "species_74016", "G3N3R4", "ENSBTAT00000064812", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "CHEBI:42976", "CHEBI:59496", "CHEBI:85986", "species_74016", "G3N3R4", "ENSBTAT00000064812" ] }, "reaction_10081943": { "compartment": "compartment_984", "id": "reaction_10081943", "reactome": "R-BTA-6806732", "name": "GNLY binds the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081939", "species_8931784" ], "products": [ "species_10081941" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083501", "species_1462049", "species_1462049", "A0A3Q1LWA5", "ENSBTAT00000083501" ] }, "reaction_10082967": { "compartment": "compartment_5083403", "id": "reaction_10082967", "reactome": "R-BTA-6810643", "name": "EPPIN protein complex binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082963" ], "products": [ "species_10082965" ], "modifiers": [], "additional_components": [ "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324", "A0A3Q1ME64", "ENSBTAT00000078640", "P24627", "ENSBTAT00000001704", "P17697", "ENSBTAT00000007324" ] }, "reaction_10084683": { "compartment": "compartment_984", "id": "reaction_10084683", "reactome": "R-BTA-8862300", "name": "LYZ binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10079373" ], "products": [ "species_10084681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038266", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10080842": { "compartment": "compartment_984", "id": "reaction_10080842", "reactome": "R-BTA-6799977", "name": "PGLYRP2 hydrolyzes bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080839", "species_109276" ], "products": [ "species_10080837", "species_6799970", "species_6799975" ], "modifiers": [ [ "species_10080837", "catalyst" ], [ "species_158417", "catalyst" ] ], "additional_components": [ "species_6789198", "E1BH94", "ENSBTAT00000047024", "E1BH94", "ENSBTAT00000047024", "CHEBI:28881", "species_1678743", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10080844": { "compartment": "compartment_984", "id": "reaction_10080844", "reactome": "R-BTA-6799981", "name": "PGLYRP2 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080837", "species_6789198" ], "products": [ "species_10080839" ], "modifiers": [], "additional_components": [ "E1BH94", "ENSBTAT00000047024", "species_6789198", "E1BH94", "ENSBTAT00000047024" ] }, "reaction_10084686": { "compartment": "compartment_984", "id": "reaction_10084686", "reactome": "R-BTA-8862320", "name": "LYZ hydrolyzes peptidoglycans in the bacterial cell wall", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_10084681" ], "products": [ "species_6788991", "species_6788982" ], "modifiers": [ [ "species_10084681", "catalyst" ] ], "additional_components": [ "P80189", "ENSBTAT00000038266", "species_6789198", "species_1236715", "CHEBI:21615", "P80189", "ENSBTAT00000038266", "species_6789198" ] }, "reaction_10058388": { "compartment": "compartment_17963", "id": "reaction_10058388", "reactome": "R-BTA-1462023", "name": "Pre-pro-defensins are cleaved to remove the signal peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058328" ], "products": [ "species_10058386" ], "modifiers": [], "additional_components": [ "A0A3Q1M0J5", "ENSBTAT00000086067", "O02775", "ENSBTAT00000009756", "A0A3Q1ME63", "ENSBTAT00000074783", "P25068", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "G3MXI5", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "Q50JB9", "ENSBTAT00000072863", "G3MWU3", "ENSBTAT00000074783", "Q5W5I5", "ENSBTAT00000069740", "A0A452DIQ0", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "Q28880", "ENSBTAT00000050266", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433", "Q28880", "ENSBTAT00000050266", "Q50JB9", "ENSBTAT00000072863", "Q5W5I5", "ENSBTAT00000069740", "G3MXI5", "ENSBTAT00000074783", "O02775", "ENSBTAT00000009756", "P25068", "ENSBTAT00000074783", "P46165", "ENSBTAT00000018930", "E1BHH4", "ENSBTAT00000074783", "F1MGE0", "ENSBTAT00000074783", "G3MWU3", "ENSBTAT00000074783", "G3MWY5", "ENSBTAT00000064773", "A0A3Q1M0J5", "ENSBTAT00000086067", "A0A3Q1ME63", "ENSBTAT00000074783", "A0A452DIQ0", "ENSBTAT00000074783", "A0A3Q1LWB5", "ENSBTAT00000078433", "A0A3Q1M5C9", "ENSBTAT00000078433", "A0A3Q1MT20", "ENSBTAT00000078433" ] }, "reaction_10081410": { "compartment": "compartment_984", "id": "reaction_10081410", "reactome": "R-BTA-6801808", "name": "REG3A,REG3G binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10081389" ], "products": [ "species_10081408" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "P23132", "ENSBTAT00000086119", "species_6789198" ] }, "reaction_10082183": { "compartment": "compartment_984", "id": "reaction_10082183", "reactome": "R-BTA-6809521", "name": "BPIF binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10082179" ], "products": [ "species_10082181" ], "modifiers": [], "additional_components": [ "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454", "F1MLW2", "ENSBTAT00000020875", "F1MI67", "ENSBTAT00000025557", "F1MHQ2", "ENSBTAT00000012052", "F6RMF1", "ENSBTAT00000044454" ] }, "reaction_10081404": { "compartment": "compartment_984", "id": "reaction_10081404", "reactome": "R-BTA-6801766", "name": "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081399" ], "products": [ "species_10081389", "species_10081401" ], "modifiers": [ [ "species_10058556", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000086119", "ENSBTAT00000028731" ] }, "reaction_10080831": { "compartment": "compartment_984", "id": "reaction_10080831", "reactome": "R-BTA-6799959", "name": "PGLYRP3,4 binds bacterial peptidoglycan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6789198", "species_10080827" ], "products": [ "species_10080829" ], "modifiers": [ [ "species_158417", "catalyst" ] ], "additional_components": [ "A0A3Q1M1U5", "ENSBTAT00000078335", "A0A3Q1M1U5", "ENSBTAT00000078335", "species_6789198" ] }, "reaction_10081406": { "compartment": "compartment_984", "id": "reaction_10081406", "reactome": "R-BTA-6801776", "name": "REG3A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081389", "species_8931784" ], "products": [ "species_10081391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086119", "species_1462049", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10087601": { "compartment": "compartment_984", "id": "reaction_10087601", "reactome": "R-BTA-8948027", "name": "RNASEs bind bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081428", "species_8931784" ], "products": [ "species_10087599" ], "modifiers": [], "additional_components": [ "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979", "species_1462049", "species_1462049", "P08904", "ENSBTAT00000011585", "A0A3Q1LIW8", "ENSBTAT00000073870", "G3MZA1", "ENSBTAT00000065979" ] }, "reaction_10081397": { "compartment": "compartment_984", "id": "reaction_10081397", "reactome": "R-BTA-6801762", "name": "REG3A oligomerize to form a pore complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081391" ], "products": [ "species_10081395" ], "modifiers": [ [ "species_166005", "inhibitor" ] ], "additional_components": [ "species_1462049", "P23132", "ENSBTAT00000086119", "species_1462049", "P23132", "ENSBTAT00000086119" ] }, "reaction_10081385": { "compartment": "compartment_984", "id": "reaction_10081385", "reactome": "R-BTA-6801687", "name": "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081382" ], "products": [ "species_10056535" ], "modifiers": [ [ "species_10080371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000044788", "ENSBTAT00000044788", "ENSBTAT00000064845" ] }, "reaction_10082977": { "compartment": "compartment_984", "id": "reaction_10082977", "reactome": "R-BTA-6810724", "name": "PI3 binds the bacterial surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803081", "species_10082971" ], "products": [ "species_10082975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000056512", "A1A4Q6", "ENSBTAT00000056512", "species_166005" ] }, "reaction_10083106": { "compartment": "compartment_984", "id": "reaction_10083106", "reactome": "R-BTA-6813659", "name": "ELANE, CTSG or PRTN3 binds bacteria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8879165", "species_10083102" ], "products": [ "species_10083104" ], "modifiers": [], "additional_components": [ "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480", "E1BAD2", "ENSBTAT00000054741", "G3MXK8", "ENSBTAT00000064845", "G3MWP1", "ENSBTAT00000064480" ] }, "reaction_10084706": { "compartment": "compartment_984", "id": "reaction_10084706", "reactome": "R-BTA-8862771", "name": "PLA2G2A binds bacterial phospholipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059808", "species_8931784" ], "products": [ "species_10084704" ], "modifiers": [], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "species_1462049", "species_1462049", "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10051836": { "compartment": "compartment_70101", "id": "reaction_10051836", "reactome": "R-BTA-879221", "name": "PSTPIP1 binds Pyrin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051824", "species_10051832" ], "products": [ "species_10051834" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q8", "ENSBTAT00000085633", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1N8Q0", "ENSBTAT00000066698", "A0A3Q1M2Q8", "ENSBTAT00000085633" ] }, "reaction_10077919": { "compartment": "compartment_21994", "id": "reaction_10077919", "reactome": "R-BTA-6789031", "name": "Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077916", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10084322": { "compartment": "compartment_984", "id": "reaction_10084322", "reactome": "R-BTA-8855490", "name": "Lactoperoxidase (LPO) produces OSCN-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_8855492" ], "products": [ "species_109276", "species_8855489" ], "modifiers": [ [ "species_10084319", "catalyst" ] ], "additional_components": [ "P80025", "ENSBTAT00000016986", "CHEBI:55376" ] }, "reaction_10086405": { "compartment": "compartment_1222282", "id": "reaction_10086405", "reactome": "R-BTA-8933635", "name": "Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_1470067", "species_6789221" ], "products": [ "species_8933637", "species_1222475" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077924": { "compartment": "compartment_1222282", "id": "reaction_10077924", "reactome": "R-BTA-6789126", "name": "Myeloperoxidase (MPO) produces hypochlorous acid (HOCl)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222719", "species_6788973", "species_1470067" ], "products": [ "species_1222475", "species_6789150" ], "modifiers": [ [ "species_10077914", "catalyst" ] ], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077926": { "compartment": "compartment_21994", "id": "reaction_10077926", "reactome": "R-BTA-6789136", "name": "Myeloperoxidase (MPO) binds to the bacterial cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077914", "species_983438" ], "products": [ "species_10077916" ], "modifiers": [], "additional_components": [ "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376", "A6QPT4", "ENSBTAT00000067752", "CHEBI:55376" ] }, "reaction_10077921": { "compartment": "compartment_1222282", "id": "reaction_10077921", "reactome": "R-BTA-6789092", "name": "NOX2 generates superoxide anion from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_1222561" ], "products": [ "species_1222461", "species_70106", "species_29366" ], "modifiers": [ [ "species_10073714", "catalyst" ] ], "additional_components": [ "O46521", "ENSBTAT00000067849", "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MKI4", "ENSBTAT00000084691", "A0A3Q1MTW8", "ENSBTAT00000076657", "Q9TU25", "ENSBTAT00000014666", "species_29438" ] }, "reaction_10077904": { "compartment": "compartment_70101", "id": "reaction_10077904", "reactome": "R-BTA-6788999", "name": "HV1-mediated H+ transfer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10077901", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10047907": { "compartment": "compartment_70101", "id": "reaction_10047907", "reactome": "R-BTA-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29368", "species_29364" ], "products": [ "species_202124", "species_29366", "species_29968" ], "modifiers": [ [ "species_10047904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069366" ] }, "reaction_10056531": { "compartment": "compartment_1222693", "id": "reaction_10056531", "reactome": "R-BTA-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10056528", "catalyst" ] ], "additional_components": [ "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "O97681", "ENSBTAT00000009563", "E1BGJ7", "ENSBTAT00000005588", "Q1RMS1", "ENSBTAT00000000367", "A0A3Q1MS24", "ENSBTAT00000075240" ] }, "reaction_10063368": { "compartment": "compartment_876", "id": "reaction_10063368", "reactome": "R-BTA-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10063365", "catalyst" ] ], "additional_components": [ "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10049304": { "compartment": "compartment_70101", "id": "reaction_10049304", "reactome": "R-BTA-432909", "name": "Interaction of Plectin with Integrin beta 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043", "species_10044490" ], "products": [ "species_10049302" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082561", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRS3", "ENSBTAT00000082561" ] }, "reaction_10075165": { "compartment": "compartment_7660", "id": "reaction_10075165", "reactome": "R-BTA-5686475", "name": "SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075149", "species_10075161" ], "products": [ "species_10075163" ], "modifiers": [], "additional_components": [ "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10075151": { "compartment": "compartment_7660", "id": "reaction_10075151", "reactome": "R-BTA-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075143", "species_10075139" ], "products": [ "species_10075149" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053203", "G3N153", "ENSBTAT00000065898", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203" ] }, "reaction_10050458": { "compartment": "compartment_70101", "id": "reaction_10050458", "reactome": "R-BTA-451056", "name": "Microtubule-independent trafficking of connexons to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050452" ], "products": [ "species_10050456" ], "modifiers": [], "additional_components": [ "A2VE67", "ENSBTAT00000023167", "A2VE67", "ENSBTAT00000023167" ] }, "reaction_10040857": { "compartment": "compartment_70101", "id": "reaction_10040857", "reactome": "R-BTA-190782", "name": "Budding of connexon-containing transport vesicles from the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040855" ], "products": [ "species_10040800" ], "modifiers": [], "additional_components": [ "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398" ] }, "reaction_10040842": { "compartment": "compartment_70101", "id": "reaction_10040842", "reactome": "R-BTA-190520", "name": "Association of Golgi transport vesicles with microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10040800" ], "products": [ "species_10040840" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "P18246", "ENSBTAT00000002398", "P18246", "ENSBTAT00000002398", "species_29438", "species_29420" ] }, "reaction_10036729": { "compartment": "compartment_7660", "id": "reaction_10036729", "reactome": "R-BTA-110231", "name": "Cleavage of uracil by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036724" ], "products": [ "species_10036726", "species_29554" ], "modifiers": [ [ "species_10036724", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036716": { "compartment": "compartment_7660", "id": "reaction_10036716", "reactome": "R-BTA-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036713" ], "products": [ "species_29692", "species_10036706" ], "modifiers": [ [ "species_10036713", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036767": { "compartment": "compartment_7660", "id": "reaction_10036767", "reactome": "R-BTA-110244", "name": "Excision of FapyG by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036764" ], "products": [ "species_10036757", "species_5636006" ], "modifiers": [ [ "species_10036764", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10036736": { "compartment": "compartment_7660", "id": "reaction_10036736", "reactome": "R-BTA-110232", "name": "Cleavage of thymine by MBD4 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036733" ], "products": [ "species_10036726", "species_29692" ], "modifiers": [ [ "species_10036733", "catalyst" ] ], "additional_components": [ "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844", "F1MUX1", "ENSBTAT00000028844" ] }, "reaction_10036709": { "compartment": "compartment_7660", "id": "reaction_10036709", "reactome": "R-BTA-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036702" ], "products": [ "species_10036706", "species_29554" ], "modifiers": [ [ "species_10036702", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10036743": { "compartment": "compartment_7660", "id": "reaction_10036743", "reactome": "R-BTA-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036740" ], "products": [ "species_10036706", "species_110233" ], "modifiers": [ [ "species_10036740", "catalyst" ] ], "additional_components": [ "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242", "A0A3Q1LSS4", "ENSBTAT00000072242" ] }, "reaction_10089640": { "compartment": "compartment_7660", "id": "reaction_10089640", "reactome": "R-BTA-9008822", "name": "PPM1D dephosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10089633" ], "products": [ "species_10086640", "species_113541" ], "modifiers": [ [ "species_10089637", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000012404" ] }, "reaction_10086716": { "compartment": "compartment_7660", "id": "reaction_10086716", "reactome": "R-BTA-8939688", "name": "SCF(SKP2) complex binds RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10086712" ], "products": [ "species_10086714" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089679": { "compartment": "compartment_70101", "id": "reaction_10089679", "reactome": "R-BTA-9009308", "name": "STUB1 polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10089672" ], "products": [ "species_10055082", "species_10089674" ], "modifiers": [ [ "species_10089672", "catalyst" ] ], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000025473", "ENSBTAT00000066565", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089681": { "compartment": "compartment_70101", "id": "reaction_10089681", "reactome": "R-BTA-9009309", "name": "RUNX2 binds STUB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089668", "species_10055082" ], "products": [ "species_10089672" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000025473", "E1B7G3", "ENSBTAT00000025473", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10086724": { "compartment": "compartment_7660", "id": "reaction_10086724", "reactome": "R-BTA-8939706", "name": "SCF(SKP2) polyubiquitinates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10086714" ], "products": [ "species_10086719", "species_10086712" ], "modifiers": [ [ "species_10086714", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565", "ENSBTAT00000066565", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10089610": { "compartment": "compartment_7660", "id": "reaction_10089610", "reactome": "R-BTA-9008412", "name": "CDK4 phosphorylates RUNX2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10086640" ], "products": [ "species_113582", "species_10089605" ], "modifiers": [ [ "species_10089607", "catalyst" ] ], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MKY5", "ENSBTAT00000066565", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10089357": { "compartment": "compartment_7660", "id": "reaction_10089357", "reactome": "R-BTA-8985343", "name": "RUNX2 binds SOX9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086213", "species_10089353" ], "products": [ "species_10089355" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066565", "ENSBTAT00000084141", "A0A3Q1MN22", "ENSBTAT00000084141", "A0A3Q1MKY5", "ENSBTAT00000066565" ] }, "reaction_10074877": { "compartment": "compartment_7660", "id": "reaction_10074877", "reactome": "R-BTA-5685319", "name": "CX3 complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10074873" ], "products": [ "species_10074875" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000013145", "A0A452DJ33", "ENSBTAT00000013145", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10065177": { "compartment": "compartment_7660", "id": "reaction_10065177", "reactome": "R-BTA-2288097", "name": "Condensin II complex binds H4K20me1-containing nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064869", "species_10064891" ], "products": [ "species_10065175" ], "modifiers": [], "additional_components": [ "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064904": { "compartment": "compartment_7660", "id": "reaction_10064904", "reactome": "R-BTA-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064897", "species_113671", "species_113685" ], "products": [ "species_10064901", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10064897", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067", "species_71067", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "species_71067" ] }, "reaction_10065563": { "compartment": "compartment_7660", "id": "reaction_10065563", "reactome": "R-BTA-2429719", "name": "MCPH1 sequesters condensin II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065559", "species_10064869", "species_10050283" ], "products": [ "species_10065561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068774", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1M8A5", "ENSBTAT00000068774" ] }, "reaction_10065201": { "compartment": "compartment_7660", "id": "reaction_10065201", "reactome": "R-BTA-2294580", "name": "PLK1 hyperphosphorylates Condensin II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065186" ], "products": [ "species_113582", "species_10065198" ], "modifiers": [ [ "species_10065186", "catalyst" ] ], "additional_components": [ "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562", "F1MPS0", "ENSBTAT00000039478", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BMZ9", "ENSBTAT00000007705", "F1MPS0", "ENSBTAT00000039478", "F1N535", "ENSBTAT00000021476", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10064733": { "compartment": "compartment_7660", "id": "reaction_10064733", "reactome": "R-BTA-2168079", "name": "MASTL (GWL) phosphorylates ARPP19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10064715" ], "products": [ "species_113582", "species_10064723" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "A0A3Q1NDP8", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1M3X4", "ENSBTAT00000075206", "A0A3Q1NDP8", "ENSBTAT00000075206", "ENSBTAT00000022950" ] }, "reaction_10065572": { "compartment": "compartment_7660", "id": "reaction_10065572", "reactome": "R-BTA-2430535", "name": "MASTL phosphorylates ENSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10065567" ], "products": [ "species_113582", "species_10065570" ], "modifiers": [ [ "species_10064730", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009379", "ENSBTAT00000009379", "ENSBTAT00000022950" ] }, "reaction_10066345": { "compartment": "compartment_70101", "id": "reaction_10066345", "reactome": "R-BTA-2984258", "name": "NEK9 phosphorylates NEK6/NEK7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066322", "species_113592" ], "products": [ "species_10066342", "species_29370" ], "modifiers": [ [ "species_10066322", "catalyst" ] ], "additional_components": [ "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10066324": { "compartment": "compartment_70101", "id": "reaction_10066324", "reactome": "R-BTA-2980720", "name": "NEK9 binds NEK6/NEK7 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066309", "species_10066320" ], "products": [ "species_10066322" ], "modifiers": [], "additional_components": [ "A6H7J4", "ENSBTAT00000070292", "F1MM88", "ENSBTAT00000022098", "F1MM88", "ENSBTAT00000022098", "A6H7J4", "ENSBTAT00000070292" ] }, "reaction_10070705": { "compartment": "compartment_13231", "id": "reaction_10070705", "reactome": "R-BTA-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10069478", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005" ] }, "reaction_10069491": { "compartment": "compartment_13231", "id": "reaction_10069491", "reactome": "R-BTA-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10069470" ], "products": [ "species_113550", "species_10069478" ], "modifiers": [ [ "species_10069488", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "A0A3Q1LKP8", "ENSBTAT00000083005", "Q1RMV9", "ENSBTAT00000025896", "Q3ZBP2", "ENSBTAT00000046962" ] }, "reaction_10065095": { "compartment": "compartment_20699", "id": "reaction_10065095", "reactome": "R-BTA-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10065087" ], "products": [ "species_10065092", "species_29370" ], "modifiers": [ [ "species_10065087", "catalyst" ] ], "additional_components": [ "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758", "species_29438", "A0A3Q1N147", "ENSBTAT00000070415", "A0A3Q1LTM9", "ENSBTAT00000084718", "A0A3Q1M072", "ENSBTAT00000084758" ] }, "reaction_10038371": { "compartment": "compartment_5460", "id": "reaction_10038371", "reactome": "R-BTA-159566", "name": "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159447" ], "products": [ "species_29374", "species_159564" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10038354": { "compartment": "compartment_5460", "id": "reaction_10038354", "reactome": "R-BTA-159443", "name": "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159446" ], "products": [ "species_159448", "species_159450", "species_159447" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10039520": { "compartment": "compartment_17906", "id": "reaction_10039520", "reactome": "R-BTA-168848", "name": "tBID binds to inactive BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037233" ], "products": [ "species_10037620" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10037237": { "compartment": "compartment_17906", "id": "reaction_10037237", "reactome": "R-BTA-114263", "name": "Oligomerization of BAK at the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037233" ], "products": [ "species_10037235" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000549", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10037622": { "compartment": "compartment_17906", "id": "reaction_10037622", "reactome": "R-BTA-139895", "name": "tBID activates BAK protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037620" ], "products": [ "species_10037269", "species_10037233" ], "modifiers": [], "additional_components": [ "Q05KI7", "ENSBTAT00000000549", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "ENSBTAT00000000549" ] }, "reaction_10047809": { "compartment": "compartment_876", "id": "reaction_10047809", "reactome": "R-BTA-400434", "name": "GPR40 (Free fatty acid receptor 1, FFAR1) binds fatty acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400427", "species_10046042" ], "products": [ "species_10046044" ], "modifiers": [], "additional_components": [ "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504", "ENSBTAT00000063172", "G3MZT6", "ENSBTAT00000063172", "species_426576", "CHEBI:50122", "species_33549", "CHEBI:16196", "CHEBI:42504" ] }, "reaction_10058908": { "compartment": "compartment_12045", "id": "reaction_10058908", "reactome": "R-BTA-1482679", "name": "PA is hydrolysed to 1-acyl LPA by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10077777": { "compartment": "compartment_70101", "id": "reaction_10077777", "reactome": "R-BTA-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10077774", "catalyst" ] ], "additional_components": [ "A0A3Q1MMR4", "ENSBTAT00000085985", "F1MSS2", "ENSBTAT00000017473" ] }, "reaction_10058896": { "compartment": "compartment_70101", "id": "reaction_10058896", "reactome": "R-BTA-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10058834": { "compartment": "compartment_17906", "id": "reaction_10058834", "reactome": "R-BTA-1482548", "name": "1-acyl LPA is acylated to PA by AGPAT5 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500580" ], "products": [ "species_1500590", "species_76194" ], "modifiers": [ [ "species_10058831", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006476" ] }, "reaction_10059860": { "compartment": "compartment_984", "id": "reaction_10059860", "reactome": "R-BTA-1602446", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602448" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10088649": { "compartment": "compartment_17906", "id": "reaction_10088649", "reactome": "R-BTA-8954398", "name": "PLD6 dimer hydrolyses cardiolipin to PA and PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189422", "species_8954419" ], "products": [ "species_8954401", "species_1500590" ], "modifiers": [ [ "species_10088630", "catalyst" ], [ "species_10088647", "catalyst" ] ], "additional_components": [ "E1BE10", "ENSBTAT00000010531", "F1MNB3", "ENSBTAT00000043938", "Q1JPG0", "ENSBTAT00000014090" ] }, "reaction_10086248": { "compartment": "compartment_984", "id": "reaction_10086248", "reactome": "R-BTA-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8878780" ], "products": [ "species_8878776", "species_109277" ], "modifiers": [ [ "species_10086245", "catalyst" ] ], "additional_components": [ "species_29426", "species_74016", "F1N2M5", "ENSBTAT00000043359" ] }, "reaction_10058923": { "compartment": "compartment_17906", "id": "reaction_10058923", "reactome": "R-BTA-1482695", "name": "G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_76194", "species_1500580" ], "modifiers": [ [ "species_10058920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015359" ] }, "reaction_10035786": { "compartment": "compartment_12045", "id": "reaction_10035786", "reactome": "R-BTA-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_426755", "species_76194" ], "modifiers": [ [ "species_10035783", "catalyst" ] ], "additional_components": [ "Q95JH2", "ENSBTAT00000083979", "A6H7D4", "ENSBTAT00000007532", "F1MZS9", "ENSBTAT00000035230", "A0A3Q1LJ33", "ENSBTAT00000076188", "G5E5P6", "ENSBTAT00000087371", "E1BGF8", "ENSBTAT00000023396", "A0A3S5ZPU2", "ENSBTAT00000006476", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10058858": { "compartment": "compartment_17906", "id": "reaction_10058858", "reactome": "R-BTA-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500590" ], "products": [ "species_1500580", "species_1524103" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059114": { "compartment": "compartment_12045", "id": "reaction_10059114", "reactome": "R-BTA-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10059111", "catalyst" ] ], "additional_components": [ "A0A3Q1MFP5", "ENSBTAT00000068010", "A0A3Q1MFB9", "ENSBTAT00000080368" ] }, "reaction_10051264": { "compartment": "compartment_12045", "id": "reaction_10051264", "reactome": "R-BTA-549112", "name": "G3P is acylated to 1-acyl LPA by AGPAT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_76114" ], "products": [ "species_1500604", "species_76194" ], "modifiers": [ [ "species_10035769", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007532" ] }, "reaction_10035812": { "compartment": "compartment_70101", "id": "reaction_10035812", "reactome": "R-BTA-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_75970", "species_73473" ], "products": [ "species_76114", "species_29360" ], "modifiers": [ [ "species_10035809", "catalyst" ] ], "additional_components": [ "A0A452DJJ3", "ENSBTAT00000021683", "A0A3Q1MUU4", "ENSBTAT00000057343" ] }, "reaction_10044235": { "compartment": "compartment_17960", "id": "reaction_10044235", "reactome": "R-BTA-211959", "name": "CYP3A43 6b-hydroxylates TEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044177", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044255": { "compartment": "compartment_17960", "id": "reaction_10044255", "reactome": "R-BTA-211968", "name": "CYP2W1 oxidises INDOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_216547" ], "products": [ "species_113519", "species_113564", "species_216598" ], "modifiers": [ [ "species_10044252", "catalyst" ] ], "additional_components": [ "F1MXW1", "ENSBTAT00000023544" ] }, "reaction_10044158": { "compartment": "compartment_17960", "id": "reaction_10044158", "reactome": "R-BTA-211874", "name": "CYP2S1 4-hydroxylates atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044155", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024282" ] }, "reaction_10044242": { "compartment": "compartment_17960", "id": "reaction_10044242", "reactome": "R-BTA-211960", "name": "CYP2U1 19-hydroxylates ARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_140356", "species_113601" ], "products": [ "species_216620", "species_113519", "species_113564" ], "modifiers": [ [ "species_10044239", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017246" ] }, "reaction_10044247": { "compartment": "compartment_17960", "id": "reaction_10044247", "reactome": "R-BTA-211962", "name": "CYP4F11 16-hydroxylates 3OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_216621", "species_113601" ], "products": [ "species_113519", "species_113564", "species_216612" ], "modifiers": [ [ "species_10044244", "catalyst" ] ], "additional_components": [ "A0A3Q1MCJ2", "ENSBTAT00000073532" ] }, "reaction_10078408": { "compartment": "compartment_70101", "id": "reaction_10078408", "reactome": "R-BTA-6793685", "name": "Ubiquitinated TP53 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675" ], "products": [ "species_10078406" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10033535": { "compartment": "compartment_7660", "id": "reaction_10033535", "reactome": "R-BTA-69685", "name": "CHEK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10033532", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000006518" ] }, "reaction_10076341": { "compartment": "compartment_7660", "id": "reaction_10076341", "reactome": "R-BTA-5693609", "name": "ATM phosphorylates TP53 at S15", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000040104" ] }, "reaction_10081470": { "compartment": "compartment_7660", "id": "reaction_10081470", "reactome": "R-BTA-6803719", "name": "TP53 binds ZNF385A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081466" ], "products": [ "species_10081468" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070196", "A0A3Q1M6W9", "ENSBTAT00000070196", "P67939", "ENSBTAT00000001420" ] }, "reaction_10057800": { "compartment": "compartment_7660", "id": "reaction_10057800", "reactome": "R-BTA-1363303", "name": "p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056559" ], "products": [ "species_10057798" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057804": { "compartment": "compartment_7660", "id": "reaction_10057804", "reactome": "R-BTA-1363306", "name": "p130 (RBL2) binds Cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056543" ], "products": [ "species_10057802" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057808": { "compartment": "compartment_7660", "id": "reaction_10057808", "reactome": "R-BTA-1363311", "name": "p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056608" ], "products": [ "species_10057806" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10057812": { "compartment": "compartment_7660", "id": "reaction_10057812", "reactome": "R-BTA-1363314", "name": "p107 (RBL1) binds CyclinE/A:CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057796", "species_10056606" ], "products": [ "species_10057810" ], "modifiers": [], "additional_components": [ "Q5E9Y0", "ENSBTAT00000005252", "ENSBTAT00000015333", "E1BMR3", "ENSBTAT00000015333", "Q5E9Y0", "ENSBTAT00000005252" ] }, "reaction_10037433": { "compartment": "compartment_70101", "id": "reaction_10037433", "reactome": "R-BTA-114558", "name": "Thrombin-activated PARs activate Gq", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037427" ], "products": [ "species_10037431", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10037353": { "compartment": "compartment_70101", "id": "reaction_10037353", "reactome": "R-BTA-114552", "name": "Thrombin-activated PARs activate G12/13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037346" ], "products": [ "species_10037350", "species_29420" ], "modifiers": [ [ "species_10037342", "catalyst" ] ], "additional_components": [ "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283" ] }, "reaction_10047880": { "compartment": "compartment_70101", "id": "reaction_10047880", "reactome": "R-BTA-418172", "name": "F2R binds ARRB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10047872" ], "products": [ "species_10047878" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "ENSBTAT00000026902", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10092299": { "compartment": "compartment_984", "id": "reaction_10092299", "reactome": "R-BTA-9708859", "name": "Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092295" ], "products": [ "species_10047872", "species_10092297" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026902", "ENSBTAT00000026902", "ENSBTAT00000026902", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10037580": { "compartment": "compartment_984", "id": "reaction_10037580", "reactome": "R-BTA-114697", "name": "Activated thrombin (factor IIa) cleaves PAR3,4, activating them", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037563" ], "products": [ "species_10037569", "species_10037342" ], "modifiers": [ [ "species_10037577", "catalyst" ] ], "additional_components": [ "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "A4IFB7", "ENSBTAT00000001191", "F1MCC4", "ENSBTAT00000012283", "species_74016", "A0A452DI66", "ENSBTAT00000009406" ] }, "reaction_10047886": { "compartment": "compartment_70101", "id": "reaction_10047886", "reactome": "R-BTA-418200", "name": "SRC-1 bound to ARRB2 is not activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047884" ], "products": [ "species_10047884" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078", "E1BIM8", "ENSBTAT00000011767", "F1N4J9", "ENSBTAT00000026902", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10041337": { "compartment": "compartment_5460", "id": "reaction_10041337", "reactome": "R-BTA-193713", "name": "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193785", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193747", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041339": { "compartment": "compartment_5460", "id": "reaction_10041339", "reactome": "R-BTA-193719", "name": "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193708", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193716", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041341": { "compartment": "compartment_70101", "id": "reaction_10041341", "reactome": "R-BTA-193727", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041343": { "compartment": "compartment_17951", "id": "reaction_10041343", "reactome": "R-BTA-193736", "name": "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193732" ], "products": [ "species_193732" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041361": { "compartment": "compartment_70101", "id": "reaction_10041361", "reactome": "R-BTA-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193707", "species_29364" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041363": { "compartment": "compartment_5460", "id": "reaction_10041363", "reactome": "R-BTA-193787", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193777", "species_113600" ], "products": [ "species_113563", "species_193782", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041365": { "compartment": "compartment_70101", "id": "reaction_10041365", "reactome": "R-BTA-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_193724", "species_70106", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041367": { "compartment": "compartment_5460", "id": "reaction_10041367", "reactome": "R-BTA-193792", "name": "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193720", "species_113529", "species_113600" ], "products": [ "species_193708", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041335": { "compartment": "compartment_70101", "id": "reaction_10041335", "reactome": "R-BTA-193711", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041193": { "compartment": "compartment_70101", "id": "reaction_10041193", "reactome": "R-BTA-192061", "name": "CYP46A1 24-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_192060", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041190", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068208" ] }, "reaction_10041353": { "compartment": "compartment_70101", "id": "reaction_10041353", "reactome": "R-BTA-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041355": { "compartment": "compartment_17951", "id": "reaction_10041355", "reactome": "R-BTA-193763", "name": "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193793" ], "products": [ "species_193422" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041357": { "compartment": "compartment_70101", "id": "reaction_10041357", "reactome": "R-BTA-193766", "name": "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193762" ], "products": [ "species_111294", "species_193741", "species_29356", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041359": { "compartment": "compartment_5460", "id": "reaction_10041359", "reactome": "R-BTA-193780", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193782", "species_113600" ], "products": [ "species_193785", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041217": { "compartment": "compartment_70101", "id": "reaction_10041217", "reactome": "R-BTA-192178", "name": "CYP39A1 7-hydroxylates 24OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192060", "species_70106", "species_29368", "species_29364" ], "products": [ "species_192189", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041214", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004736" ] }, "reaction_10041345": { "compartment": "compartment_5460", "id": "reaction_10041345", "reactome": "R-BTA-193737", "name": "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193716", "species_113600" ], "products": [ "species_193757", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041347": { "compartment": "compartment_70101", "id": "reaction_10041347", "reactome": "R-BTA-193743", "name": "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193778" ], "products": [ "species_111294", "species_29356", "species_193739", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041349": { "compartment": "compartment_70101", "id": "reaction_10041349", "reactome": "R-BTA-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193724", "species_70106", "species_29364" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041351": { "compartment": "compartment_70101", "id": "reaction_10041351", "reactome": "R-BTA-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_193707", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10047659": { "compartment": "compartment_70101", "id": "reaction_10047659", "reactome": "R-BTA-399939", "name": "Autophosphorylation of PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047616" ], "products": [ "species_29370", "species_10047656" ], "modifiers": [ [ "species_10047616", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047763": { "compartment": "compartment_70101", "id": "reaction_10047763", "reactome": "R-BTA-399952", "name": "Phosphorylation of LIMK-1 by PAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047757" ], "products": [ "species_29370", "species_10047760" ], "modifiers": [ [ "species_10047656", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061497", "ENSBTAT00000061497", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260" ] }, "reaction_10047618": { "compartment": "compartment_70101", "id": "reaction_10047618", "reactome": "R-BTA-399930", "name": "Activation of PAK by Rac1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047612", "species_10047592" ], "products": [ "species_10047616", "species_10047614" ], "modifiers": [], "additional_components": [ "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "A0A3Q1M0G8", "ENSBTAT00000082239" ] }, "reaction_10047753": { "compartment": "compartment_70101", "id": "reaction_10047753", "reactome": "R-BTA-399951", "name": "Phosphorylation of CRMPs by GSK3beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047714", "species_113592" ], "products": [ "species_10047750", "species_29370" ], "modifiers": [ [ "species_10041574", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "ENSBTAT00000056446" ] }, "reaction_10047717": { "compartment": "compartment_70101", "id": "reaction_10047717", "reactome": "R-BTA-399944", "name": "Phosphorylation of CRMPs by Cdk5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047695", "species_10047675" ], "products": [ "species_10047714", "species_29370" ], "modifiers": [ [ "species_10047695", "catalyst" ] ], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "A8E641", "ENSBTAT00000085592", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "A0JNB0", "ENSBTAT00000015730", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064", "F1N173", "ENSBTAT00000030185", "F1N2P7", "ENSBTAT00000019327", "E1BFR4", "ENSBTAT00000030589", "F1MIH8", "ENSBTAT00000001558", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859" ] }, "reaction_10047735": { "compartment": "compartment_70101", "id": "reaction_10047735", "reactome": "R-BTA-399947", "name": "Tyrosine phosphorylation of CRMPs by Fes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047586", "species_113592", "species_10047675" ], "products": [ "species_10047732", "species_29370" ], "modifiers": [ [ "species_10043848", "catalyst" ] ], "additional_components": [ "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "Q5E9H3", "ENSBTAT00000003828", "E1BFR4", "ENSBTAT00000030589", "F1N2P7", "ENSBTAT00000019327", "F1MIH8", "ENSBTAT00000001558", "F1N173", "ENSBTAT00000030185", "A0JNB0", "ENSBTAT00000015730", "E1BMX5", "ENSBTAT00000026471", "F1MEW1", "ENSBTAT00000080859", "E1BER6", "ENSBTAT00000005625", "A2VDS7", "ENSBTAT00000023643", "A8E641", "ENSBTAT00000085592", "ENSBTAT00000003828" ] }, "reaction_10045244": { "compartment": "compartment_876", "id": "reaction_10045244", "reactome": "R-BTA-373748", "name": "SEMA4D interacts with CD72", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045240" ], "products": [ "species_10045242" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000015162", "E1BPB4", "ENSBTAT00000015162", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10045236": { "compartment": "compartment_876", "id": "reaction_10045236", "reactome": "R-BTA-373746", "name": "SEMA4D interacts with CD45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045232", "species_10045228" ], "products": [ "species_10045234" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083792", "ENSBTAT00000013320", "F1MJS9", "ENSBTAT00000013320", "A0A3Q1LQU8", "ENSBTAT00000083792" ] }, "reaction_10089713": { "compartment": "compartment_984", "id": "reaction_10089713", "reactome": "R-BTA-9010815", "name": "SLITs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089709", "species_2299699" ], "products": [ "species_10089711" ], "modifiers": [], "additional_components": [ "F1MLJ7", "ENSBTAT00000061059", "species_2299699", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10090179": { "compartment": "compartment_984", "id": "reaction_10090179", "reactome": "R-BTA-9014812", "name": "ROBOs bind keratan sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043663", "species_2299699" ], "products": [ "species_10090177" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061264", "species_2299699", "F1N739", "ENSBTAT00000061264" ] }, "reaction_10045517": { "compartment": "compartment_70101", "id": "reaction_10045517", "reactome": "R-BTA-376141", "name": "Interaction of ABL with ROBO1:SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10045513" ], "products": [ "species_10045515" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "ENSBTAT00000080797", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10049024": { "compartment": "compartment_70101", "id": "reaction_10049024", "reactome": "R-BTA-428888", "name": "Phosphorylation of ROBO1 by ABL kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10045515" ], "products": [ "species_29370", "species_10049021" ], "modifiers": [ [ "species_10045515", "catalyst" ] ], "additional_components": [ "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "A0A3Q1LI98", "ENSBTAT00000080797", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10089397": { "compartment": "compartment_876", "id": "reaction_10089397", "reactome": "R-BTA-8986258", "name": "SLIT2:ROBO1 binds CXCR4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043669", "species_10089393" ], "products": [ "species_10089395" ], "modifiers": [], "additional_components": [ "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "P25930", "ENSBTAT00000001406", "A0A3Q1M085", "ENSBTAT00000077980", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048935": { "compartment": "compartment_876", "id": "reaction_10048935", "reactome": "R-BTA-428518", "name": "Glypican-1 (GPC1) binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048931", "species_10043667" ], "products": [ "species_10048933" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "ENSBTAT00000061059", "A0A3Q1LZ29", "ENSBTAT00000082766", "CHEBI:17421", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10043671": { "compartment": "compartment_876", "id": "reaction_10043671", "reactome": "R-BTA-204364", "name": "ROBO1 binds SLIT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043667", "species_10043663" ], "products": [ "species_10043669" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061059", "ENSBTAT00000061264", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10048951": { "compartment": "compartment_70101", "id": "reaction_10048951", "reactome": "R-BTA-428534", "name": "Recruitment of Profilin by Ena/VASP proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048947", "species_10043457" ], "products": [ "species_10048949" ], "modifiers": [], "additional_components": [ "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059", "F1N214", "ENSBTAT00000021544", "A0A3Q1MSR1", "ENSBTAT00000069763", "F1N739", "ENSBTAT00000061264", "F1MLJ7", "ENSBTAT00000061059" ] }, "reaction_10047449": { "compartment": "compartment_70101", "id": "reaction_10047449", "reactome": "R-BTA-392051", "name": "Recruitment of Grb2 to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047443", "species_10035485" ], "products": [ "species_10047447" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000006216", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10047455": { "compartment": "compartment_70101", "id": "reaction_10047455", "reactome": "R-BTA-392053", "name": "SOS binds Grb2 bound to pFAK:NCAM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047447", "species_10035489" ], "products": [ "species_10047453" ], "modifiers": [], "additional_components": [ "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000015471", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10047458": { "compartment": "compartment_70101", "id": "reaction_10047458", "reactome": "R-BTA-392054", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10040312" ], "products": [ "species_29420", "species_10039728" ], "modifiers": [ [ "species_10047453", "catalyst" ] ], "additional_components": [ "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29420", "A0A3Q1LKB7", "ENSBTAT00000071009", "A5D7R9", "ENSBTAT00000012897", "species_29438", "A0A3Q1LI10", "ENSBTAT00000073047", "E1BMN5", "ENSBTAT00000007787", "F1MKE9", "ENSBTAT00000006213", "F1MMQ8", "ENSBTAT00000061417", "A0A3Q1LNC8", "ENSBTAT00000066559", "A0JNB0", "ENSBTAT00000015730", "Q3T0F9", "ENSBTAT00000006216", "A0A3Q1N508", "ENSBTAT00000085237", "F1N7C3", "ENSBTAT00000015471" ] }, "reaction_10045509": { "compartment": "compartment_876", "id": "reaction_10045509", "reactome": "R-BTA-376122", "name": "DSCAM/DSCAML1 homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045505" ], "products": [ "species_10045507" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082055", "A0A3Q1MBH9", "ENSBTAT00000082055" ] }, "reaction_10045224": { "compartment": "compartment_70101", "id": "reaction_10045224", "reactome": "R-BTA-373738", "name": "Neurofascin interacts with syntenin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10045216" ], "products": [ "species_10045222" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "ENSBTAT00000069125", "A0A3Q1LMZ3", "ENSBTAT00000069125", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069192": { "compartment": "compartment_70101", "id": "reaction_10069192", "reactome": "R-BTA-3928615", "name": "EFNBs bind SFKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069057", "species_10069161" ], "products": [ "species_10069190" ], "modifiers": [], "additional_components": [ "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069226": { "compartment": "compartment_70101", "id": "reaction_10069226", "reactome": "R-BTA-3928640", "name": "PAKs phosphorylate MLC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049739" ], "products": [ "species_10049762", "species_29370" ], "modifiers": [ [ "species_10069218", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021328", "ENSBTAT00000021328", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438" ] }, "reaction_10069418": { "compartment": "compartment_70101", "id": "reaction_10069418", "reactome": "R-BTA-4093329", "name": "EFNBs bind SDCBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045220", "species_10069057" ], "products": [ "species_10069416" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026526", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F6QH17", "ENSBTAT00000026526" ] }, "reaction_10069221": { "compartment": "compartment_70101", "id": "reaction_10069221", "reactome": "R-BTA-3928625", "name": "PAKs autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069208" ], "products": [ "species_10069218", "species_29370" ], "modifiers": [ [ "species_10069208", "catalyst" ] ], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749", "Q08E52", "ENSBTAT00000080749", "A0A3Q1LSY0", "ENSBTAT00000085260", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530", "species_29438", "A0A3Q1LSY0", "ENSBTAT00000085260", "Q08E52", "ENSBTAT00000080749" ] }, "reaction_10069188": { "compartment": "compartment_70101", "id": "reaction_10069188", "reactome": "R-BTA-3928614", "name": "EFNB:GRB4 binds GIT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069184", "species_10069179" ], "products": [ "species_10069186" ], "modifiers": [], "additional_components": [ "ENSBTAT00000073530", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542", "A0A3Q1M7Q3", "ENSBTAT00000073530" ] }, "reaction_10069223": { "compartment": "compartment_70101", "id": "reaction_10069223", "reactome": "R-BTA-3928639", "name": "p-EFNB binds GRB4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045210", "species_10069177" ], "products": [ "species_10069179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069542", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "A6H720", "ENSBTAT00000069542" ] }, "reaction_10069243": { "compartment": "compartment_876", "id": "reaction_10069243", "reactome": "R-BTA-3928646", "name": "EPHAs bind EFNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068993", "species_10069023" ], "products": [ "species_10069025" ], "modifiers": [], "additional_components": [ "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958" ] }, "reaction_10069131": { "compartment": "compartment_876", "id": "reaction_10069131", "reactome": "R-BTA-3928591", "name": "EPH:EFN tetramers oligomerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069127", "species_10069129" ], "products": [ "species_10069061" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069285": { "compartment": "compartment_876", "id": "reaction_10069285", "reactome": "R-BTA-3928656", "name": "gamma-secretase cleaves EPHB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069263" ], "products": [ "species_10069283", "species_10069273" ], "modifiers": [ [ "species_10057233", "catalyst" ] ], "additional_components": [ "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "A0A3Q1LNM1", "ENSBTAT00000068424", "A0A3Q1MBH7", "ENSBTAT00000086383", "A0A3Q1MDC6", "ENSBTAT00000075241", "Q5G235", "ENSBTAT00000024745" ] }, "reaction_10069157": { "compartment": "compartment_876", "id": "reaction_10069157", "reactome": "R-BTA-3928604", "name": "SFKs phosphorylate VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10069152" ], "products": [ "species_10069154", "species_29370" ], "modifiers": [ [ "species_10069152", "catalyst" ] ], "additional_components": [ "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069159": { "compartment": "compartment_876", "id": "reaction_10069159", "reactome": "R-BTA-3928607", "name": "p-EPHs bind VAV2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069150", "species_10048073" ], "products": [ "species_10069152" ], "modifiers": [], "additional_components": [ "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "ENSBTAT00000086853", "A0A3Q1MQP9", "ENSBTAT00000086853", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696" ] }, "reaction_10069194": { "compartment": "compartment_876", "id": "reaction_10069194", "reactome": "R-BTA-3928624", "name": "EPHBs bind EFNBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069055", "species_10069037" ], "products": [ "species_10069057" ], "modifiers": [], "additional_components": [ "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069146": { "compartment": "compartment_876", "id": "reaction_10069146", "reactome": "R-BTA-3928597", "name": "EPH:EFN dimers tetramerise", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069129" ], "products": [ "species_10069127" ], "modifiers": [], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069121": { "compartment": "compartment_70101", "id": "reaction_10069121", "reactome": "R-BTA-3928578", "name": "EPH receptors autophosphorylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069061", "species_113592" ], "products": [ "species_29370", "species_10069118" ], "modifiers": [ [ "species_10069061", "catalyst" ] ], "additional_components": [ "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MAA9", "ENSBTAT00000083978", "A0A3Q1MJW2", "ENSBTAT00000075696", "E1BJS9", "ENSBTAT00000008955", "F1MKR1", "ENSBTAT00000037789", "E1BER5", "ENSBTAT00000013238", "A0A3Q1MJW2", "ENSBTAT00000075696", "A0A3Q1MAA9", "ENSBTAT00000083978", "F1N6H6", "ENSBTAT00000033263", "A0A3Q1MTB6", "ENSBTAT00000067384", "A6QLY0", "ENSBTAT00000033972", "Q3ZC64", "ENSBTAT00000004007", "Q17R05", "ENSBTAT00000080646", "A5D7J8", "ENSBTAT00000053096", "F1N163", "ENSBTAT00000026958", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "F1ML02", "ENSBTAT00000006988", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780" ] }, "reaction_10069144": { "compartment": "compartment_70101", "id": "reaction_10069144", "reactome": "R-BTA-3928592", "name": "p190RhoGEF exchanges GTP for GDP on RHOA, activating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10037313" ], "products": [ "species_29420", "species_10037315" ], "modifiers": [ [ "species_10069141", "catalyst" ] ], "additional_components": [ "P61585", "ENSBTAT00000005600", "species_29420", "P61585", "ENSBTAT00000005600", "species_29438", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10069435": { "compartment": "compartment_876", "id": "reaction_10069435", "reactome": "R-BTA-4093339", "name": "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069428", "species_29356" ], "products": [ "species_29372", "species_10069432" ], "modifiers": [ [ "species_10069428", "catalyst" ] ], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29420", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1LKB7", "ENSBTAT00000071009", "species_29438" ] }, "reaction_10069148": { "compartment": "compartment_70101", "id": "reaction_10069148", "reactome": "R-BTA-3928598", "name": "Recruitment of p190RhoGEF to p-FAK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069139", "species_10069135" ], "products": [ "species_10069141" ], "modifiers": [], "additional_components": [ "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237", "ENSBTAT00000074225", "A0A3Q1LKT3", "ENSBTAT00000074225", "E1BIE4", "ENSBTAT00000037233", "F1MII5", "ENSBTAT00000020455", "F1N3R6", "ENSBTAT00000026780", "F1ML02", "ENSBTAT00000006988", "A0A3Q1LXH4", "ENSBTAT00000086732", "F1N0M5", "ENSBTAT00000035350", "A0A3Q1N508", "ENSBTAT00000085237" ] }, "reaction_10091007": { "compartment": "compartment_12045", "id": "reaction_10091007", "reactome": "R-BTA-9614271", "name": "Autocleavage of ADGRG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090998" ], "products": [ "species_10091004" ], "modifiers": [ [ "species_10090998", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895", "ENSBTAT00000079895" ] }, "reaction_10091009": { "compartment": "compartment_876", "id": "reaction_10091009", "reactome": "R-BTA-9614273", "name": "ADGRG heterodimer translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091004" ], "products": [ "species_10091004" ], "modifiers": [], "additional_components": [ "A0A3Q1MTZ4", "ENSBTAT00000079895", "A0A3Q1MTZ4", "ENSBTAT00000079895" ] }, "reaction_10074603": { "compartment": "compartment_876", "id": "reaction_10074603", "reactome": "R-BTA-5682709", "name": "LGI4 binds ADAM22,23,11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074599", "species_10074595" ], "products": [ "species_10074601" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025189", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "A0A3Q1MPN5", "ENSBTAT00000077549", "A6QLD0", "ENSBTAT00000025189" ] }, "reaction_10074641": { "compartment": "compartment_984", "id": "reaction_10074641", "reactome": "R-BTA-5682802", "name": "LGI3 binds ADAM22,23,synatxin1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074637" ], "products": [ "species_10074639" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000006011", "E1BFY8", "ENSBTAT00000006011", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10074613": { "compartment": "compartment_984", "id": "reaction_10074613", "reactome": "R-BTA-5682769", "name": "LGI2 binds ADAM22,23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074609", "species_10074607" ], "products": [ "species_10074611" ], "modifiers": [], "additional_components": [ "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985", "ENSBTAT00000023124", "F1MZT1", "ENSBTAT00000023124", "A0A3Q1NF99", "ENSBTAT00000081521", "A0A3Q1MVZ5", "ENSBTAT00000071985" ] }, "reaction_10081915": { "compartment": "compartment_70101", "id": "reaction_10081915", "reactome": "R-BTA-6806610", "name": "Keratin filament formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081911" ], "products": [ "species_10081913" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081917": { "compartment": "compartment_70101", "id": "reaction_10081917", "reactome": "R-BTA-6806613", "name": "Keratin tetramers bind to form unit length filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081859" ], "products": [ "species_10081909" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081857": { "compartment": "compartment_70101", "id": "reaction_10081857", "reactome": "R-BTA-6805546", "name": "Keratin type I binds keratin type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081853", "species_10081739" ], "products": [ "species_10081855" ], "modifiers": [], "additional_components": [ "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081921": { "compartment": "compartment_70101", "id": "reaction_10081921", "reactome": "R-BTA-6806629", "name": "Formation of tonofilament bundles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081913" ], "products": [ "species_10081919" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10081861": { "compartment": "compartment_70101", "id": "reaction_10081861", "reactome": "R-BTA-6805573", "name": "Keratin type I/type II heterodimers form tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081855" ], "products": [ "species_10081859" ], "modifiers": [], "additional_components": [ "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396" ] }, "reaction_10082871": { "compartment": "compartment_70101", "id": "reaction_10082871", "reactome": "R-BTA-6809663", "name": "Formation of hair keratin fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082865", "species_10081919" ], "products": [ "species_10082869" ], "modifiers": [], "additional_components": [ "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "A0A3Q1LZF2", "ENSBTAT00000074051", "A0A3Q1M139", "ENSBTAT00000087011", "F1MI98", "ENSBTAT00000006440", "Q148I8", "ENSBTAT00000018185", "A0A3Q1MPF8", "ENSBTAT00000072411", "A6QP90", "ENSBTAT00000013107", "A0A3Q1LV22", "ENSBTAT00000076314", "F1N3T1", "ENSBTAT00000026752", "A7YWM2", "ENSBTAT00000023156", "Q0P5J4", "ENSBTAT00000043116", "A6H712", "ENSBTAT00000043126", "A0A3Q1M4F4", "ENSBTAT00000071728", "F6S1Q0", "ENSBTAT00000001988", "A0A3Q1LJB2", "ENSBTAT00000083663", "P08728", "ENSBTAT00000006450", "G3X7W8", "ENSBTAT00000047914", "F1MFW9", "ENSBTAT00000027749", "G3MX98", "ENSBTAT00000064531", "Q17QL7", "ENSBTAT00000006445", "A3KMY1", "ENSBTAT00000009403", "F1N362", "ENSBTAT00000021519", "A0A3Q1M0W3", "ENSBTAT00000077014", "A0A452DI61", "ENSBTAT00000008857", "E1B898", "ENSBTAT00000018307", "F1N566", "ENSBTAT00000038457", "Q148H4", "ENSBTAT00000038458", "A6QP32", "ENSBTAT00000038471", "Q148H8", "ENSBTAT00000010391", "A7YWK3", "ENSBTAT00000010393", "A4IFP2", "ENSBTAT00000016832", "A0A3Q1MDN1", "ENSBTAT00000067366", "G3N0V2", "ENSBTAT00000065029", "F1MKE7", "ENSBTAT00000057443", "A6QNX5", "ENSBTAT00000000815", "G3MZ71", "ENSBTAT00000063931", "A0A452DIJ6", "ENSBTAT00000016839", "A0A3Q1MYR8", "ENSBTAT00000072474", "F1MUY2", "ENSBTAT00000046815", "M0QVY0", "ENSBTAT00000000396", "G3MYE1", "ENSBTAT00000064142", "G3MX57", "ENSBTAT00000065975", "Q24JX9", "ENSBTAT00000064111", "Q05B46", "ENSBTAT00000049339", "G3MWP0", "ENSBTAT00000063461", "G3N2U6", "ENSBTAT00000064310", "Q05B44", "ENSBTAT00000024766", "A0A3Q1M8D5", "ENSBTAP00000066373", "E1B9G9", "ENSBTAP00000053063", "A0A3Q1LRY2", "ENSBTAT00000071483", "A0A3Q1N0M4", "ENSBTAT00000069096", "A0A3Q1LY72", "ENSBTAT00000083666", "A0A3Q1N1L4", "ENSBTAT00000084386", "A0A3Q1M0F6", "ENSBTAT00000084386", "E1BAH7", "ENSBTAT00000083666", "A0A3Q1MWC2", "ENSBTAT00000068881", "F1N3V7", "ENSBTAT00000043153", "A0A3Q1LK19", "ENSBTAT00000087153", "A0A3Q1MEE6", "ENSBTAT00000087153", "A0A3Q1LNZ0", "ENSBTAT00000087153", "A6QP35", "ENSBTAT00000043652", "A0A3Q1LUM3", "ENSBTAT00000068312", "F6RZX2", "ENSBTAT00000043662", "A0A3Q1LYD7", "ENSBTAT00000087153", "A0A3Q1LUR9", "ENSBTAT00000071394", "G3N073", "ENSBTAT00000063306", "A0A3Q1LPJ2", "ENSBTAT00000084954", "A0A3Q1MLT3", "ENSBTAT00000085549", "A7YWJ9", "ENSBTAT00000043142", "E1BIW5", "ENSBTAT00000034860", "A0A3Q1MFR3", "ENSBTAT00000075891", "A0A3Q1NF50", "ENSBTAT00000082065", "A0A3Q1MN32", "ENSBTAT00000084052", "A7E345", "ENSBTAT00000043148", "A0A3Q1LFA4", "ENSBTAT00000084052", "A0A3Q1N1W4", "ENSBTAT00000084052", "E1BMY6", "ENSBTAT00000043146", "A0A3Q1LQD4", "ENSBTAT00000084052", "A0A3Q1N892", "ENSBTAT00000084052", "E1BMY7", "ENSBTAT00000043145", "A0A3Q1M5Z5", "ENSBTAT00000078641", "A0A3Q1LSL9", "ENSBTAT00000080742", "A0A3Q1NHC3", "ENSBTAT00000072065", "A0A3Q1N3D2", "ENSBTAT00000082261", "Q0VC31", "ENSBTAT00000065867", "A5PJJ0", "ENSBTAT00000056985", "A5PJJ4", "ENSBTAT00000056308", "F1MTA9", "ENSBTAP00000021000", "A0A3Q1N0A2", "ENSBTAT00000075298" ] }, "reaction_10050085": { "compartment": "compartment_7660", "id": "reaction_10050085", "reactome": "R-BTA-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050064", "species_10050074" ], "products": [ "species_113582", "species_10050082" ], "modifiers": [ [ "species_10050074", "catalyst" ] ], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "A0A3Q1NNL3", "ENSBTAT00000079928", "A0A3Q1LJZ7", "ENSBTAT00000073649", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10050116": { "compartment": "compartment_7660", "id": "reaction_10050116", "reactome": "R-BTA-448963", "name": "Interaction of MyoD:E protein with MEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050080", "species_10050112" ], "products": [ "species_10050114" ], "modifiers": [], "additional_components": [ "A0A3Q1NNL3", "ENSBTAT00000079928", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "P17667", "ENSBTAT00000038612", "Q7YS81", "ENSBTAT00000007923", "A0A3Q1LQN2", "ENSBTAT00000071565", "A0A3Q1NNL3", "ENSBTAT00000079928" ] }, "reaction_10044090": { "compartment": "compartment_7660", "id": "reaction_10044090", "reactome": "R-BTA-211178", "name": "Phosphorylated FOXO1A is excluded from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042680" ], "products": [ "species_10044088" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061127", "ENSBTAT00000061127" ] }, "reaction_10071769": { "compartment": "compartment_7660", "id": "reaction_10071769", "reactome": "R-BTA-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071589", "species_10071585" ], "products": [ "species_10071591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082240", "ENSBTAT00000022288", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071640": { "compartment": "compartment_7660", "id": "reaction_10071640", "reactome": "R-BTA-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10071626" ], "products": [ "species_113582", "species_10071603" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592" ] }, "reaction_10071628": { "compartment": "compartment_7660", "id": "reaction_10071628", "reactome": "R-BTA-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10071624" ], "products": [ "species_10071626" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071630": { "compartment": "compartment_7660", "id": "reaction_10071630", "reactome": "R-BTA-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_5358610" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10071767": { "compartment": "compartment_7660", "id": "reaction_10071767", "reactome": "R-BTA-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071599", "species_10071595" ], "products": [ "species_10071624" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001867", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_29370" ] }, "reaction_10071607": { "compartment": "compartment_7660", "id": "reaction_10071607", "reactome": "R-BTA-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071591", "species_10039892", "species_10071603" ], "products": [ "species_10071605" ], "modifiers": [], "additional_components": [ "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3ZBW4", "ENSBTAT00000007967", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071622": { "compartment": "compartment_7660", "id": "reaction_10071622", "reactome": "R-BTA-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071605" ], "products": [ "species_10071619" ], "modifiers": [ [ "species_10071605", "catalyst" ] ], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071638": { "compartment": "compartment_7660", "id": "reaction_10071638", "reactome": "R-BTA-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071634", "species_10071619" ], "products": [ "species_10071636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012365", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240", "Q3MHE4", "ENSBTAT00000003556", "E1B9Q4", "ENSBTAT00000001867", "species_113592", "E1BF15", "ENSBTAT00000012365", "Q3ZBW4", "ENSBTAT00000007967", "F1MPG0", "ENSBTAT00000022288", "A0A3Q1M1S8", "ENSBTAT00000082240" ] }, "reaction_10071617": { "compartment": "compartment_7660", "id": "reaction_10071617", "reactome": "R-BTA-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10071613" ], "products": [ "species_10071615" ], "modifiers": [], "additional_components": [ "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10071765": { "compartment": "compartment_7660", "id": "reaction_10071765", "reactome": "R-BTA-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10071611", "species_10071595" ], "products": [ "species_10071613" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076740", "ENSBTAT00000003556", "Q3MHE4", "ENSBTAT00000003556", "A0A3Q1LUI6", "ENSBTAT00000076740", "species_29370" ] }, "reaction_10047196": { "compartment": "compartment_70101", "id": "reaction_10047196", "reactome": "R-BTA-390595", "name": "Calcium Binds Troponin-C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10047192" ], "products": [ "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047198": { "compartment": "compartment_70101", "id": "reaction_10047198", "reactome": "R-BTA-390597", "name": "Release Of ADP From Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047181" ], "products": [ "species_29370", "species_10047194" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572" ] }, "reaction_10047200": { "compartment": "compartment_70101", "id": "reaction_10047200", "reactome": "R-BTA-390598", "name": "Myosin Binds ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10047194" ], "products": [ "species_10047177" ], "modifiers": [], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10047186": { "compartment": "compartment_70101", "id": "reaction_10047186", "reactome": "R-BTA-390593", "name": "ATP Hydrolysis By Myosin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047177" ], "products": [ "species_29372", "species_10047181" ], "modifiers": [ [ "species_10047183", "catalyst" ] ], "additional_components": [ "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "species_113592", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "A0A3Q1MC60", "ENSBTAT00000086078", "Q5KR48", "ENSBTAT00000046179", "species_74016", "F6QIC1", "ENSBTAT00000014452", "G3MYN5", "ENSBTAT00000063025", "G3N264", "ENSBTAT00000065361", "P68138", "ENSBTAT00000006534", "A0A3Q1LWR2", "ENSBTAT00000083316", "A0A3Q1M4Y0", "ENSBTAT00000082241", "A0A3Q1LQC6", "ENSBTAT00000076718", "A6QP89", "ENSBTAT00000043649", "species_29370", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007", "O62654", "ENSBTAT00000007041", "Q6T8D8", "ENSBTAT00000015579", "P48616", "ENSBTAT00000024572", "A6QPA6", "ENSBTAT00000001120", "F1N2G0", "ENSBTAT00000007359", "A0A3Q1LVZ9", "ENSBTAT00000085880", "A0JNJ5", "ENSBTAT00000054271", "A0A3Q1M165", "ENSBTAT00000075504", "Q1RMM7", "ENSBTAT00000057007" ] }, "reaction_10071824": { "compartment": "compartment_70101", "id": "reaction_10071824", "reactome": "R-BTA-5577237", "name": "KCNH2:KCNE transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071821", "catalyst" ] ], "additional_components": [ "Q2KHV0", "ENSBTAT00000001530", "Q2NKS7", "ENSBTAT00000037245", "A0A3Q1LSF6", "ENSBTAT00000067149" ] }, "reaction_10077468": { "compartment": "compartment_984", "id": "reaction_10077468", "reactome": "R-BTA-6784598", "name": "NPPA(124-151) binds NPR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071836", "species_10077464" ], "products": [ "species_10077466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008819", "E1BN71", "ENSBTAT00000008184", "E1BN71", "ENSBTAT00000008184", "P07501", "ENSBTAT00000008819" ] }, "reaction_10071843": { "compartment": "compartment_876", "id": "reaction_10071843", "reactome": "R-BTA-5578783", "name": "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071828" ], "products": [ "species_10071830", "species_10071836", "species_10071834", "species_10071832" ], "modifiers": [ [ "species_10071840", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000008819", "ENSBTAT00000085692" ] }, "reaction_10071819": { "compartment": "compartment_876", "id": "reaction_10071819", "reactome": "R-BTA-5577234", "name": "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071816", "catalyst" ] ], "additional_components": [ "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "A0A3Q1LV43", "ENSBTAT00000072593", "A0A3Q1M5I5", "ENSBTAT00000066696" ] }, "reaction_10053180": { "compartment": "compartment_876", "id": "reaction_10053180", "reactome": "R-BTA-936897", "name": "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_113592", "species_83910" ], "products": [ "species_29372", "species_29804", "species_29370", "species_74113" ], "modifiers": [ [ "species_10053175", "catalyst" ], [ "species_10053178", "inhibitor" ] ], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10091759": { "compartment": "compartment_984", "id": "reaction_10091759", "reactome": "R-BTA-9684068", "name": "ATP1A:ATP1B:FXYD binds cardiac glycosides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053175", "species_9684063" ], "products": [ "species_10053178" ], "modifiers": [], "additional_components": [ "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582", "Q3T0C6", "ENSBTAT00000018795", "A6QLL5", "ENSBTAT00000018181", "A2VDL6", "ENSBTAT00000049161", "E1B8N5", "ENSBTAT00000013951", "A0A3Q1MJB8", "ENSBTAT00000077228", "A0A3Q1LWV7", "ENSBTAT00000073582" ] }, "reaction_10048787": { "compartment": "compartment_12045", "id": "reaction_10048787", "reactome": "R-BTA-427910", "name": "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_156540", "species_74016" ], "products": [ "species_70106", "species_111875" ], "modifiers": [ [ "species_10048770", "catalyst" ], [ "species_10048785", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158", "species_74016", "A0A3Q1MR28", "ENSBTAT00000044622", "A0A3Q1MKC7", "ENSBTAT00000073084", "A0A3Q1M066", "ENSBTAT00000071596" ] }, "reaction_10047893": { "compartment": "compartment_876", "id": "reaction_10047893", "reactome": "R-BTA-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10047890", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077323" ] }, "reaction_10071876": { "compartment": "compartment_70101", "id": "reaction_10071876", "reactome": "R-BTA-5578910", "name": "KCNK dimers transport K+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10071873", "catalyst" ] ], "additional_components": [ "E1BEH3", "ENSBTAT00000004382", "A0A3Q1MT89", "ENSBTAT00000075452", "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182" ] }, "reaction_10035579": { "compartment": "compartment_12045", "id": "reaction_10035579", "reactome": "R-BTA-74872", "name": "RDH10,11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_10035564" ], "products": [ "species_70106", "species_10035566", "species_29364" ], "modifiers": [ [ "species_10035576", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q8HZT6", "ENSBTAT00000026830", "E1BM93", "ENSBTAT00000002535" ] }, "reaction_10065597": { "compartment": "compartment_12045", "id": "reaction_10065597", "reactome": "R-BTA-2454081", "name": "RDH5 oxidises 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_29360" ], "products": [ "species_70106", "species_10035566", "species_73473" ], "modifiers": [ [ "species_10065594", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "species_32737", "Q27979", "ENSBTAT00000065932" ] }, "reaction_10065644": { "compartment": "compartment_70101", "id": "reaction_10065644", "reactome": "R-BTA-2454264", "name": "11cROL binds to RLBP1 to form RLBP1:11cROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30927", "species_10035562" ], "products": [ "species_10035564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_2473611" ] }, "reaction_10035406": { "compartment": "compartment_2514888", "id": "reaction_10035406", "reactome": "R-BTA-74101", "name": "Photons induce isomerization of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419777", "species_10035401" ], "products": [ "species_10035404" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10065646": { "compartment": "compartment_70101", "id": "reaction_10065646", "reactome": "R-BTA-2464809", "name": "RBP3 regulates the transport of atROL from ROS to RPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473615" ], "products": [ "species_2473604" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10088914": { "compartment": "compartment_70101", "id": "reaction_10088914", "reactome": "R-BTA-8960973", "name": "RLBP1:11cRAL dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035566" ], "products": [ "species_8960974", "species_10035562" ], "modifiers": [], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_32737", "ENSBTAT00000047900" ] }, "reaction_10065604": { "compartment": "compartment_70101", "id": "reaction_10065604", "reactome": "R-BTA-2454113", "name": "RBP3 transports 11cRAL to rod photoreceptor outer segment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8960974" ], "products": [ "species_32737" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10077751": { "compartment": "compartment_12045", "id": "reaction_10077751", "reactome": "R-BTA-6786239", "name": "CYP4V2 omega-hydroxylates DHA to HDoHE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6786220", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6786225" ], "modifiers": [ [ "species_10077748", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085962" ] }, "reaction_10035558": { "compartment": "compartment_70101", "id": "reaction_10035558", "reactome": "R-BTA-74843", "name": "atROL binds RBP1 to form RBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035554", "species_2473604" ], "products": [ "species_10035556" ], "modifiers": [], "additional_components": [ "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936", "species_975590", "A0A3Q1LU75", "ENSBTAT00000012885", "A0A452DJ95", "ENSBTAT00000015936" ] }, "reaction_10065606": { "compartment": "compartment_70101", "id": "reaction_10065606", "reactome": "R-BTA-2454118", "name": "11cRAL binds to opsin to form 11c-retinyl:RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2565923", "species_32737" ], "products": [ "species_29356", "species_10035401" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730" ] }, "reaction_10049433": { "compartment": "compartment_876", "id": "reaction_10049433", "reactome": "R-BTA-442317", "name": "ZIP6 and ZIP14 mediate zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049430", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065246" ] }, "reaction_10049464": { "compartment": "compartment_876", "id": "reaction_10049464", "reactome": "R-BTA-442422", "name": "SLC39A1-4 transports Zn2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049461", "catalyst" ] ], "additional_components": [ "Q3SYU3", "ENSBTAT00000034015", "E1BEU4", "ENSBTAT00000001238", "A0A3Q1LWM2", "ENSBTAT00000075196" ] }, "reaction_10049440": { "compartment": "compartment_876", "id": "reaction_10049440", "reactome": "R-BTA-442387", "name": "ZIP8 mediates zinc influx into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158417" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049437", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007448" ] }, "reaction_10049447": { "compartment": "compartment_12045", "id": "reaction_10049447", "reactome": "R-BTA-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10049444", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010771" ] }, "reaction_10071469": { "compartment": "compartment_70101", "id": "reaction_10071469", "reactome": "R-BTA-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10071466", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006554" ] }, "reaction_10070735": { "compartment": "compartment_70101", "id": "reaction_10070735", "reactome": "R-BTA-5226964", "name": "ANKH transports PPi from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294" ], "products": [ "species_113542" ], "modifiers": [ [ "species_10070732", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017818" ] }, "reaction_10071280": { "compartment": "compartment_984", "id": "reaction_10071280", "reactome": "R-BTA-5252072", "name": "AZGP1 binds PIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071266", "species_10071276" ], "products": [ "species_10071278" ], "modifiers": [], "additional_components": [ "ENSBTAT00000037204", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "F1MCV8", "ENSBTAT00000008743", "A0A3Q1N598", "ENSBTAT00000079328", "A0A452DK44", "ENSBTAT00000037204" ] }, "reaction_10071490": { "compartment": "compartment_70101", "id": "reaction_10071490", "reactome": "R-BTA-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071487", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065645" ] }, "reaction_10087365": { "compartment": "compartment_70101", "id": "reaction_10087365", "reactome": "R-BTA-8941543", "name": "VRAC heteromer transports I-, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8941540" ], "products": [ "species_8941541" ], "modifiers": [ [ "species_10087362", "catalyst" ] ], "additional_components": [ "species_352022", "species_209785", "species_209785", "species_352022", "A4IFE5", "ENSBTAT00000027912", "Q08E42", "ENSBTAT00000084512", "F6PRJ0", "ENSBTAT00000005636", "A5PK13", "ENSBTAT00000085971" ] }, "reaction_10071476": { "compartment": "compartment_70101", "id": "reaction_10071476", "reactome": "R-BTA-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071473", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012110" ] }, "reaction_10086343": { "compartment": "compartment_70101", "id": "reaction_10086343", "reactome": "R-BTA-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10086340", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:32551", "species_113530", "species_113530", "species_29612", "CHEBI:32551", "ENSBTAT00000018143" ] }, "reaction_10071462": { "compartment": "compartment_70101", "id": "reaction_10071462", "reactome": "R-BTA-5336453", "name": "NIPAs transport Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10071459", "catalyst" ] ], "additional_components": [ "F1N136", "ENSBTAT00000002985" ] }, "reaction_10047930": { "compartment": "compartment_70101", "id": "reaction_10047930", "reactome": "R-BTA-418456", "name": "cGMP is degraded by PDEs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30991" ], "products": [ "species_113578" ], "modifiers": [ [ "species_10047927", "catalyst" ] ], "additional_components": [ "A0A3Q1MZ56", "ENSBTAT00000078870", "A0A3Q1MW13", "ENSBTAT00000079827", "P14100", "ENSBTAT00000052318", "E1BPD8", "ENSBTAT00000021805", "A0A3Q1N569", "ENSBTAT00000072103" ] }, "reaction_10065369": { "compartment": "compartment_70101", "id": "reaction_10065369", "reactome": "R-BTA-2395869", "name": "NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065371": { "compartment": "compartment_70101", "id": "reaction_10065371", "reactome": "R-BTA-2395872", "name": "NUDT1 hydrolyses 2-OH-ATP to 2-OH-AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395868" ], "products": [ "species_111294", "species_2395878" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065386": { "compartment": "compartment_70101", "id": "reaction_10065386", "reactome": "R-BTA-2395965", "name": "NUDT18 hydrolyses 8-OH-dADP to 8-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395963", "species_29356" ], "products": [ "species_29372", "species_2395964" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065359": { "compartment": "compartment_70101", "id": "reaction_10065359", "reactome": "R-BTA-2395818", "name": "NUDT1 hydrolyses 2-OH-dATP to 2-OH-dAMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395822" ], "products": [ "species_111294", "species_2395855" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065760": { "compartment": "compartment_7660", "id": "reaction_10065760", "reactome": "R-BTA-2509793", "name": "NUDT16 hydrolyses dIDP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509796" ], "products": [ "species_113550", "species_2509805" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065328": { "compartment": "compartment_5460", "id": "reaction_10065328", "reactome": "R-BTA-2393954", "name": "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2393945", "species_113521" ], "products": [ "species_2393950", "species_159448" ], "modifiers": [ [ "species_10065325", "catalyst" ] ], "additional_components": [ "A7MBI8", "ENSBTAT00000015090", "species_29926" ] }, "reaction_10065763": { "compartment": "compartment_7660", "id": "reaction_10065763", "reactome": "R-BTA-2509816", "name": "NUDT16 hydrolyses IDP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_2509811" ], "products": [ "species_113550", "species_2509792" ], "modifiers": [ [ "species_10065757", "catalyst" ], [ "species_2509819", "catalyst" ] ], "additional_components": [ "A1A4Q9", "ENSBTAT00000053197" ] }, "reaction_10065362": { "compartment": "compartment_70101", "id": "reaction_10065362", "reactome": "R-BTA-2395849", "name": "NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395852" ], "products": [ "species_111294", "species_2395817" ], "modifiers": [ [ "species_10065356", "catalyst" ] ], "additional_components": [ "F1MLL8", "ENSBTAT00000003218", "species_29926" ] }, "reaction_10065378": { "compartment": "compartment_70101", "id": "reaction_10065378", "reactome": "R-BTA-2395873", "name": "NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2395880" ], "products": [ "species_29372", "species_2395877" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065381": { "compartment": "compartment_70101", "id": "reaction_10065381", "reactome": "R-BTA-2395876", "name": "NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025978" ] }, "reaction_10065383": { "compartment": "compartment_70101", "id": "reaction_10065383", "reactome": "R-BTA-2395879", "name": "NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2395883", "species_29356" ], "products": [ "species_2395817", "species_29372" ], "modifiers": [ [ "species_10065375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004527" ] }, "reaction_10065319": { "compartment": "compartment_70101", "id": "reaction_10065319", "reactome": "R-BTA-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10065316", "catalyst" ] ], "additional_components": [ "species_29926", "F1MMR8", "ENSBTAT00000068724" ] }, "reaction_10072489": { "compartment": "compartment_70101", "id": "reaction_10072489", "reactome": "R-BTA-5624131", "name": "UNC119B binds myristoylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072485", "species_10072480" ], "products": [ "species_10072487" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007584", "ENSBTAT00000009843", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10072497": { "compartment": "compartment_18730", "id": "reaction_10072497", "reactome": "R-BTA-5624132", "name": "UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072487" ], "products": [ "species_10072495" ], "modifiers": [], "additional_components": [ "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584", "E1BIZ3", "ENSBTAT00000009843", "E1BP93", "ENSBTAT00000007584" ] }, "reaction_10033379": { "compartment": "compartment_7660", "id": "reaction_10033379", "reactome": "R-BTA-68637", "name": "CDC6 protein is synthesized under the control of E2F transcription factors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10033367" ], "modifiers": [ [ "species_10033377", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083861", "E1BG94", "ENSBTAT00000005182", "E1BD75", "ENSBTAT00000023554" ] }, "reaction_10033412": { "compartment": "compartment_70101", "id": "reaction_10033412", "reactome": "R-BTA-68712", "name": "The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033408", "species_10033390" ], "products": [ "species_10033410", "species_10033388" ], "modifiers": [], "additional_components": [ "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336", "Q56JZ0", "ENSBTAT00000023040", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000067336" ] }, "reaction_10085788": { "compartment": "compartment_70101", "id": "reaction_10085788", "reactome": "R-BTA-8873794", "name": "PCTP binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075605", "species_1524163" ], "products": [ "species_10085786" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024898", "species_429785", "P02720", "ENSBTAT00000024898" ] }, "reaction_10086064": { "compartment": "compartment_12045", "id": "reaction_10086064", "reactome": "R-BTA-8877153", "name": "STARD7 binds PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10086060" ], "products": [ "species_10086062" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071992", "A0A3Q1LZP9", "ENSBTAT00000071992", "species_429785" ] }, "reaction_10085808": { "compartment": "compartment_70101", "id": "reaction_10085808", "reactome": "R-BTA-8873923", "name": "STARD10 binds LPCAT1 and PC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035781", "species_426925", "species_10085792" ], "products": [ "species_10085794" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001250", "ENSBTAT00000071421", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250" ] }, "reaction_10085024": { "compartment": "compartment_984", "id": "reaction_10085024", "reactome": "R-BTA-8865637", "name": "MFSD2A transports LPC from extracellular region to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8865642", "species_74113" ], "products": [ "species_8865629", "species_83910" ], "modifiers": [ [ "species_10085021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017353" ] }, "reaction_10059141": { "compartment": "compartment_12045", "id": "reaction_10059141", "reactome": "R-BTA-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10059138", "catalyst" ] ], "additional_components": [ "A0A3Q1LKP8", "ENSBTAT00000083005", "species_29926", "A0A3Q1LV95", "ENSBTAT00000067199", "E1BLQ9", "ENSBTAT00000012081" ] }, "reaction_10059063": { "compartment": "compartment_70101", "id": "reaction_10059063", "reactome": "R-BTA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_264618", "species_113592" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10059060", "catalyst" ] ], "additional_components": [ "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10085798": { "compartment": "compartment_70101", "id": "reaction_10085798", "reactome": "R-BTA-8873834", "name": "STARD10 transports PC from ER membrane to lamellar body membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085794" ], "products": [ "species_10085796", "species_10035781" ], "modifiers": [], "additional_components": [ "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "F1MTK4", "ENSBTAT00000001250", "A0A3Q1MRL1", "ENSBTAT00000071421", "species_429785", "ENSBTAT00000001250" ] }, "reaction_10059094": { "compartment": "compartment_70101", "id": "reaction_10059094", "reactome": "R-BTA-1483159", "name": "PCho is dephosphorylated to Cho by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524071" ], "products": [ "species_264618", "species_29372" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10090489": { "compartment": "compartment_70101", "id": "reaction_10090489", "reactome": "R-BTA-9026780", "name": "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10090480": { "compartment": "compartment_70101", "id": "reaction_10090480", "reactome": "R-BTA-9026777", "name": "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9025001" ], "products": [ "species_9026761" ], "modifiers": [ [ "species_10039964", "catalyst" ] ], "additional_components": [ "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425" ] }, "reaction_10090491": { "compartment": "compartment_70101", "id": "reaction_10090491", "reactome": "R-BTA-9026911", "name": "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024768" ], "products": [ "species_9026915" ], "modifiers": [ [ "species_10090486", "catalyst" ] ], "additional_components": [ "Q2NKS0", "ENSBTAT00000012836" ] }, "reaction_10044835": { "compartment": "compartment_70101", "id": "reaction_10044835", "reactome": "R-BTA-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10044837": { "compartment": "compartment_70101", "id": "reaction_10044837", "reactome": "R-BTA-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_353555", "species_76194" ], "modifiers": [ [ "species_10044832", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023087" ] }, "reaction_10076360": { "compartment": "compartment_876", "id": "reaction_10076360", "reactome": "R-BTA-5693681", "name": "DUOX1,2 reduce O2 to H2O2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352327" ], "products": [ "species_351628", "species_351629" ], "modifiers": [ [ "species_10076357", "catalyst" ] ], "additional_components": [ "E1BMK1", "ENSBTAT00000021618", "E1BMS3", "ENSBTAT00000021603" ] }, "reaction_10043978": { "compartment": "compartment_876", "id": "reaction_10043978", "reactome": "R-BTA-209910", "name": "Iodide is taken up by thyroid epithelial cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10044828": { "compartment": "compartment_984", "id": "reaction_10044828", "reactome": "R-BTA-350901", "name": "Iodide is organified", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_209818", "species_351629" ], "products": [ "species_109276", "species_351630", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043980": { "compartment": "compartment_984", "id": "reaction_10043980", "reactome": "R-BTA-209925", "name": "DIT and MIT combine to form triiodothyronine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329", "species_351639" ], "products": [ "species_352331", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10043986": { "compartment": "compartment_984", "id": "reaction_10043986", "reactome": "R-BTA-209973", "name": "Tyrosine is diiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_351627", "species_352030", "species_209818", "species_351629" ], "products": [ "species_109276", "species_352329", "species_351628" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043924": { "compartment": "compartment_984", "id": "reaction_10043924", "reactome": "R-BTA-209815", "name": "Tyrosine is monoiodinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351630", "species_352030" ], "products": [ "species_622410", "species_351639" ], "modifiers": [ [ "species_10043921", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301" ] }, "reaction_10043956": { "compartment": "compartment_984", "id": "reaction_10043956", "reactome": "R-BTA-209840", "name": "Two DITs combine to form thyroxine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352329" ], "products": [ "species_352326", "species_352036" ], "modifiers": [ [ "species_10043921", "catalyst" ], [ "species_10043954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071301", "P01217", "ENSBTAT00000078886", "P01223", "ENSBTAT00000008264" ] }, "reaction_10066745": { "compartment": "compartment_7660", "id": "reaction_10066745", "reactome": "R-BTA-3222128", "name": "NOC2L binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066741" ], "products": [ "species_10066743" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021980", "Q3SYU1", "ENSBTAT00000021980", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066712": { "compartment": "compartment_7660", "id": "reaction_10066712", "reactome": "R-BTA-3222020", "name": "NUAK1 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066701" ], "products": [ "species_113582", "species_10066709", "species_10066690", "species_10066699" ], "modifiers": [ [ "species_10066701", "catalyst" ] ], "additional_components": [ "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081563": { "compartment": "compartment_7660", "id": "reaction_10081563", "reactome": "R-BTA-6805035", "name": "TP53 binds STK11 and NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066694", "species_10066677", "species_10066690" ], "products": [ "species_10066696" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013805", "P67939", "ENSBTAT00000001420", "ENSBTAT00000015459", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10081595": { "compartment": "compartment_7660", "id": "reaction_10081595", "reactome": "R-BTA-6805276", "name": "CDK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10081585" ], "modifiers": [ [ "species_10081592", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "Q02399", "ENSBTAT00000010212", "Q28199", "ENSBTAT00000056064" ] }, "reaction_10080730": { "compartment": "compartment_7660", "id": "reaction_10080730", "reactome": "R-BTA-6799431", "name": "TP53 binds HIPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080726", "species_10066677" ], "products": [ "species_10080728" ], "modifiers": [], "additional_components": [ "ENSBTAT00000015051", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BQ34", "ENSBTAT00000015051" ] }, "reaction_10081629": { "compartment": "compartment_7660", "id": "reaction_10081629", "reactome": "R-BTA-6805479", "name": "TP53RK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081626", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000039179" ] }, "reaction_10066704": { "compartment": "compartment_7660", "id": "reaction_10066704", "reactome": "R-BTA-3222006", "name": "STK11 (LKB1) phosphorylates NUAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066696" ], "products": [ "species_113582", "species_10066701" ], "modifiers": [ [ "species_10066696", "catalyst" ] ], "additional_components": [ "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805", "E1B9B6", "ENSBTAT00000013805", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1BCU9", "ENSBTAT00000015459", "P67939", "ENSBTAT00000001420", "E1B9B6", "ENSBTAT00000013805" ] }, "reaction_10080722": { "compartment": "compartment_7660", "id": "reaction_10080722", "reactome": "R-BTA-6799409", "name": "HIPK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066668" ], "products": [ "species_113582", "species_10066659", "species_10066666", "species_10078728" ], "modifiers": [ [ "species_10066668", "catalyst" ] ], "additional_components": [ "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "P67939", "ENSBTAT00000001420", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066870": { "compartment": "compartment_7660", "id": "reaction_10066870", "reactome": "R-BTA-3239014", "name": "MAPKAPK5 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10066862" ], "modifiers": [ [ "species_10066867", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10081622": { "compartment": "compartment_7660", "id": "reaction_10081622", "reactome": "R-BTA-6805470", "name": "AMPK phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066677" ], "products": [ "species_113582", "species_10033519" ], "modifiers": [ [ "species_10081619", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10078731": { "compartment": "compartment_7660", "id": "reaction_10078731", "reactome": "R-BTA-6798374", "name": "DYRK2 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033524" ], "products": [ "species_113582", "species_10078728" ], "modifiers": [ [ "species_10078718", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000009545" ] }, "reaction_10066670": { "compartment": "compartment_7660", "id": "reaction_10066670", "reactome": "R-BTA-3215251", "name": "TP53INP1 and HIPK2 bind TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066659", "species_10066666" ], "products": [ "species_10066668" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000084811", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MHM3", "ENSBTAT00000072457", "Q5BIN5", "ENSBTAT00000022592", "A0A3Q1MBC1", "ENSBTAT00000084811", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078720": { "compartment": "compartment_7660", "id": "reaction_10078720", "reactome": "R-BTA-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10078714" ], "products": [ "species_113582", "species_10078718" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009545", "ENSBTAT00000009545", "ENSBTAT00000040104" ] }, "reaction_10081602": { "compartment": "compartment_7660", "id": "reaction_10081602", "reactome": "R-BTA-6805285", "name": "PLK3 phosphorylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10033519" ], "products": [ "species_113582", "species_10033524" ], "modifiers": [ [ "species_10081599", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000008055" ] }, "reaction_10039801": { "compartment": "compartment_7660", "id": "reaction_10039801", "reactome": "R-BTA-174097", "name": "Association of Emi1 with Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039797" ], "products": [ "species_10039799" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "Q32L05", "ENSBTAT00000074490", "Q32L05", "ENSBTAT00000074490", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10039852": { "compartment": "compartment_7660", "id": "reaction_10039852", "reactome": "R-BTA-174235", "name": "Association of Emi1 with Cdc20", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038468", "species_10039803" ], "products": [ "species_10039850" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083057", "ENSBTAT00000077512", "F1MRW5", "ENSBTAT00000077512", "A0A3Q1M5V7", "ENSBTAT00000083057" ] }, "reaction_10038033": { "compartment": "compartment_70101", "id": "reaction_10038033", "reactome": "R-BTA-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038027" ], "products": [ "species_10038031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10038035": { "compartment": "compartment_70101", "id": "reaction_10038035", "reactome": "R-BTA-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038023", "species_10038019", "species_10038015", "species_10038027" ], "products": [ "species_10038029" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077512", "ENSBTAT00000057027", "ENSBTAT00000009521", "ENSBTAT00000065027", "G3MX31", "ENSBTAT00000065027", "F1MWP1", "ENSBTAT00000009521", "Q1JQB2", "ENSBTAT00000057027", "F1MRW5", "ENSBTAT00000077512" ] }, "reaction_10033833": { "compartment": "compartment_70101", "id": "reaction_10033833", "reactome": "R-BTA-70903", "name": "urocanate + H2O => 4-imidazolone-5-propionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30721" ], "products": [ "species_34979" ], "modifiers": [ [ "species_10033830", "catalyst" ] ], "additional_components": [ "species_29360", "A0A3Q1LXH7", "ENSBTAT00000083727" ] }, "reaction_10033849": { "compartment": "compartment_70101", "id": "reaction_10033849", "reactome": "R-BTA-70920", "name": "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30158", "species_111355" ], "products": [ "species_29404", "species_70919" ], "modifiers": [ [ "species_10033846", "catalyst" ] ], "additional_components": [ "A0A3Q1MBB6", "ENSBTAT00000074746" ] }, "reaction_10054585": { "compartment": "compartment_70101", "id": "reaction_10054585", "reactome": "R-BTA-977301", "name": "Histidine is decarboxylated to histamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612" ], "products": [ "species_175992", "species_113528" ], "modifiers": [ [ "species_10054582", "catalyst" ] ], "additional_components": [ "Q5EA83", "ENSBTAT00000013083" ] }, "reaction_10077758": { "compartment": "compartment_70101", "id": "reaction_10077758", "reactome": "R-BTA-6786245", "name": "CARNS1 transforms ATP, L-His, b-Ala to CARN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29612", "species_113592", "species_73590" ], "products": [ "species_6786250", "species_29372", "species_29370" ], "modifiers": [ [ "species_10077755", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023529" ] }, "reaction_10086033": { "compartment": "compartment_70101", "id": "reaction_10086033", "reactome": "R-BTA-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10086030", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010790" ] }, "reaction_10033840": { "compartment": "compartment_70101", "id": "reaction_10033840", "reactome": "R-BTA-70906", "name": "4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_34979" ], "products": [ "species_30158", "species_70106" ], "modifiers": [ [ "species_10033837", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021647" ] }, "reaction_10059066": { "compartment": "compartment_70616", "id": "reaction_10059066", "reactome": "R-BTA-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524072", "species_1524067" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10092237": { "compartment": "compartment_7660", "id": "reaction_10092237", "reactome": "R-BTA-9707523", "name": "Hemes bind to BACH1:MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707575", "species_10092233" ], "products": [ "species_10055987", "species_10092235" ], "modifiers": [], "additional_components": [ "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092269": { "compartment": "compartment_70101", "id": "reaction_10092269", "reactome": "R-BTA-9708423", "name": "XPO1:BACH1:Hemes are transported out of the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092259" ], "products": [ "species_10092267" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092239": { "compartment": "compartment_7660", "id": "reaction_10092239", "reactome": "R-BTA-9707690", "name": "BACH1 binds MAFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231", "species_10055987" ], "products": [ "species_10092233" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000025702", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092271": { "compartment": "compartment_7660", "id": "reaction_10092271", "reactome": "R-BTA-9708430", "name": "XPO1 (CRM1) binds to BACH1:Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092235", "species_10050265" ], "products": [ "species_10092259" ], "modifiers": [], "additional_components": [ "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092225": { "compartment": "compartment_984", "id": "reaction_10092225", "reactome": "R-BTA-9707505", "name": "Hemes bind to CLEC1B dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10092221" ], "products": [ "species_10092223" ], "modifiers": [], "additional_components": [ "species_71185", "E1BLL1", "ENSBTAT00000053034", "E1BLL1", "ENSBTAT00000053034", "species_71185" ] }, "reaction_10092227": { "compartment": "compartment_984", "id": "reaction_10092227", "reactome": "R-BTA-9707516", "name": "FeHM dissociates from MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743" ], "products": [ "species_917955", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10052914": { "compartment": "compartment_876", "id": "reaction_10052914", "reactome": "R-BTA-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10042919", "catalyst" ] ], "additional_components": [ "species_71185", "ENSBTAT00000035283" ] }, "reaction_10092214": { "compartment": "compartment_984", "id": "reaction_10092214", "reactome": "R-BTA-9707504", "name": "H2O2 oxidises ferrohemoglobin to MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_351629" ], "products": [ "species_10064743", "species_9707624", "species_9707647" ], "modifiers": [ [ "species_10092212", "inhibitor" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10081561": { "compartment": "compartment_7660", "id": "reaction_10081561", "reactome": "R-BTA-6804762", "name": "TP53 forms homotetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066422" ], "products": [ "species_10066677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420" ] }, "reaction_10091685": { "compartment": "compartment_7660", "id": "reaction_10091685", "reactome": "R-BTA-9670114", "name": "Histone H3.3 deposition at telomere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091677", "species_10035227" ], "products": [ "species_10091683", "species_10040161" ], "modifiers": [], "additional_components": [ "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000034695", "F1MGU0", "ENSBTAT00000036227", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "Q5E9F8", "ENSBTAT00000034695", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000033058" ] }, "reaction_10038540": { "compartment": "compartment_7660", "id": "reaction_10038540", "reactome": "R-BTA-163099", "name": "Alignment Of The RNA Template On The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038538" ], "products": [ "species_10038529" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10038947": { "compartment": "compartment_7660", "id": "reaction_10038947", "reactome": "R-BTA-164617", "name": "Elongation of Extended Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_10038531", "species_30185", "species_29892", "species_29604" ], "products": [ "species_10038542" ], "modifiers": [ [ "species_10038531", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038949": { "compartment": "compartment_7660", "id": "reaction_10038949", "reactome": "R-BTA-164620", "name": "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038531" ], "products": [ "species_10038531" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986" ] }, "reaction_10038534": { "compartment": "compartment_7660", "id": "reaction_10038534", "reactome": "R-BTA-163090", "name": "Elongation Of The Telomeric Chromosome End", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30187", "species_30185", "species_10038529", "species_29892", "species_29604" ], "products": [ "species_10038531" ], "modifiers": [ [ "species_10038529", "catalyst" ] ], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363", "CHEBI:15986", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "CHEBI:15986", "F1N079", "ENSBTAT00000028108", "Q3ZBF2", "ENSBTAT00000036177", "A7YWH5", "ENSBTAT00000017339", "A0A3Q1M1J8", "ENSBTAT00000066873", "A0A3Q1LGY5", "ENSBTAT00000071579", "Q5E950", "ENSBTAT00000008363" ] }, "reaction_10087577": { "compartment": "compartment_17957", "id": "reaction_10087577", "reactome": "R-BTA-8944242", "name": "Association of procollagen type XXVII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062035" ], "products": [ "species_10062840" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081723", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10087579": { "compartment": "compartment_17957", "id": "reaction_10087579", "reactome": "R-BTA-8944246", "name": "Association of procollagen type XXI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062810" ], "products": [ "species_10062812" ], "modifiers": [], "additional_components": [ "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1MQC5", "ENSBTAT00000074238" ] }, "reaction_10087581": { "compartment": "compartment_17957", "id": "reaction_10087581", "reactome": "R-BTA-8944247", "name": "Association of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060135", "species_10060159", "species_10060111" ], "products": [ "species_10060183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025663", "ENSBTAT00000018479", "ENSBTAT00000015668", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087583": { "compartment": "compartment_17957", "id": "reaction_10087583", "reactome": "R-BTA-8944250", "name": "Association of procollagen type XXV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062400" ], "products": [ "species_10062823" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087569": { "compartment": "compartment_17957", "id": "reaction_10087569", "reactome": "R-BTA-8944219", "name": "Association of procollagen type XVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062025" ], "products": [ "species_10062790" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065364", "G3MXK9", "ENSBTAT00000065364" ] }, "reaction_10087571": { "compartment": "compartment_17957", "id": "reaction_10087571", "reactome": "R-BTA-8944220", "name": "Association of procollagen type XXIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062031" ], "products": [ "species_10062821" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017548", "F1MSJ7", "ENSBTAT00000017548" ] }, "reaction_10087573": { "compartment": "compartment_17957", "id": "reaction_10087573", "reactome": "R-BTA-8944223", "name": "Association of procollagen type V", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062017", "species_10062045", "species_10062041" ], "products": [ "species_10062749" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063052", "ENSBTAT00000013440", "ENSBTAT00000084344", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052" ] }, "reaction_10062071": { "compartment": "compartment_17957", "id": "reaction_10062071", "reactome": "R-BTA-2002401", "name": "Association of procollagen type XVIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062037" ], "products": [ "species_10062069" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067622", "A0A3Q1LYA4", "ENSBTAT00000067622" ] }, "reaction_10087563": { "compartment": "compartment_17957", "id": "reaction_10087563", "reactome": "R-BTA-8944215", "name": "Association of procollagen type XX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062027" ], "products": [ "species_10062801" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063888", "G3N021", "ENSBTAT00000063888" ] }, "reaction_10087565": { "compartment": "compartment_17957", "id": "reaction_10087565", "reactome": "R-BTA-8944216", "name": "Association of procollagen type XV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062023" ], "products": [ "species_10062781" ], "modifiers": [], "additional_components": [ "ENSBTAT00000072268", "A0A3Q1M0N0", "ENSBTAT00000072268" ] }, "reaction_10087567": { "compartment": "compartment_17957", "id": "reaction_10087567", "reactome": "R-BTA-8944218", "name": "Association of procollagen type VIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062019", "species_10062043" ], "products": [ "species_10062763" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018159", "ENSBTAT00000083731", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159" ] }, "reaction_10087585": { "compartment": "compartment_17957", "id": "reaction_10087585", "reactome": "R-BTA-8944254", "name": "Association of procollagen type XXVI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062033" ], "products": [ "species_10062832" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044319", "E1BKJ9", "ENSBTAT00000044319" ] }, "reaction_10087587": { "compartment": "compartment_17957", "id": "reaction_10087587", "reactome": "R-BTA-8944261", "name": "Association of procollagen type XIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062021" ], "products": [ "species_10062772" ], "modifiers": [], "additional_components": [ "ENSBTAT00000039811", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10087589": { "compartment": "compartment_17957", "id": "reaction_10087589", "reactome": "R-BTA-8944263", "name": "Association of procollagen type II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062015" ], "products": [ "species_10062709" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017505", "P02459", "ENSBTAT00000017505" ] }, "reaction_10044446": { "compartment": "compartment_7660", "id": "reaction_10044446", "reactome": "R-BTA-212356", "name": "Formation of CSL-NICD coactivator complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10044434", "species_10044414", "species_10044442", "species_10044410", "species_10044424" ], "products": [ "species_10044444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "A0A3Q1MLT2", "ENSBTAT00000075969", "ENSBTAT00000050083", "ENSBTAT00000010697", "ENSBTAT00000004696", "A0A3Q1MF28", "ENSBTAT00000078064", "A0A3Q1MF28", "ENSBTAT00000078064", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "G3X812", "ENSBTAT00000050083", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10044726": { "compartment": "compartment_7660", "id": "reaction_10044726", "reactome": "R-BTA-350058", "name": "Formation of CSL NCOR corepressor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10044722", "species_10044704", "species_10044442", "species_10044410" ], "products": [ "species_10044724" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000010697", "ENSBTAT00000004696", "Q3SZ41", "ENSBTAT00000004696", "Q1JQE0", "ENSBTAT00000010697", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "A0A3Q1MXW3", "ENSBTAT00000084577", "F1N0W0", "ENSBTAT00000023086", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092287": { "compartment": "compartment_7660", "id": "reaction_10092287", "reactome": "R-BTA-9708517", "name": "FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2))", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10092281" ], "products": [ "species_10092277", "species_10092284", "species_10086712" ], "modifiers": [ [ "species_10092281", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000069043", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092273": { "compartment": "compartment_70101", "id": "reaction_10092273", "reactome": "R-BTA-9708466", "name": "BACH1 translocates from the nucleoplasm to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092231" ], "products": [ "species_10092261" ], "modifiers": [ [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005416", "ENSBTAT00000005416" ] }, "reaction_10092289": { "compartment": "compartment_7660", "id": "reaction_10092289", "reactome": "R-BTA-9708525", "name": "BACH1:FBXL17 binds SCF(SKP2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092279", "species_10086712" ], "products": [ "species_10092281" ], "modifiers": [], "additional_components": [ "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416" ] }, "reaction_10092293": { "compartment": "compartment_7660", "id": "reaction_10092293", "reactome": "R-BTA-9708557", "name": "FBXL17 binds BACH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092277", "species_10092233" ], "products": [ "species_10092279", "species_10055987" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069043", "E1BB01", "ENSBTAT00000025702", "E1BJL3", "ENSBTAT00000005416", "A0A3Q1LUD8", "ENSBTAT00000069043", "E1BJL3", "ENSBTAT00000005416", "ENSBTAT00000025702" ] }, "reaction_10057639": { "compartment": "compartment_876", "id": "reaction_10057639", "reactome": "R-BTA-1299304", "name": "Activation of tandem pore domain in a weak inwardly rectifying K+ channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057636", "catalyst" ] ], "additional_components": [ "Q0P5A0", "ENSBTAT00000005929", "F1MX91", "ENSBTAT00000032182", "E1B9M4", "ENSBTAT00000014309" ] }, "reaction_10065673": { "compartment": "compartment_70101", "id": "reaction_10065673", "reactome": "R-BTA-2465919", "name": "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035564", "species_200993" ], "products": [ "species_10065666", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "P10123", "ENSBTAT00000047900", "species_2473611", "P10123", "ENSBTAT00000047900", "CHEBI:16254", "ENSBTAT00000074877" ] }, "reaction_10091560": { "compartment": "compartment_70101", "id": "reaction_10091560", "reactome": "R-BTA-9656893", "name": "OPN1MW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065675": { "compartment": "compartment_70101", "id": "reaction_10065675", "reactome": "R-BTA-2465924", "name": "OPN1LW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048186", "species_32737" ], "products": [ "species_29356", "species_10065649" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027054", "ENSBTAT00000027054" ] }, "reaction_10065677": { "compartment": "compartment_70101", "id": "reaction_10065677", "reactome": "R-BTA-2465934", "name": "11cROL translocates from Muller cells to cone photoreceptor cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473606" ], "products": [ "species_2473611" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065679": { "compartment": "compartment_70101", "id": "reaction_10065679", "reactome": "R-BTA-2465938", "name": "RBP3 regulates atROL taken up by Muller cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473607" ], "products": [ "species_2473617" ], "modifiers": [ [ "species_10065601", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006585" ] }, "reaction_10065664": { "compartment": "compartment_74000", "id": "reaction_10065664", "reactome": "R-BTA-2465917", "name": "Photons induce isomerisation of 11c-retinyl to at-retinyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065654", "species_419777" ], "products": [ "species_10065662" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10065683": { "compartment": "compartment_70101", "id": "reaction_10065683", "reactome": "R-BTA-2465971", "name": "RLBP1 binds atROL to form RLBP1:atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2473617", "species_10035562" ], "products": [ "species_10065681" ], "modifiers": [], "additional_components": [ "ENSBTAT00000047900", "P10123", "ENSBTAT00000047900", "species_975590" ] }, "reaction_10065687": { "compartment": "compartment_70101", "id": "reaction_10065687", "reactome": "R-BTA-2466085", "name": "at-retinyl is hydrolysed from R* to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10065662" ], "products": [ "species_10065685", "species_975622" ], "modifiers": [], "additional_components": [ "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912", "Q9BGI7", "ENSBTAT00000027054", "P51490", "ENSBTAT00000021912" ] }, "reaction_10091558": { "compartment": "compartment_70101", "id": "reaction_10091558", "reactome": "R-BTA-9656891", "name": "OPN1SW binds 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048190", "species_32737" ], "products": [ "species_10065652", "species_29356" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021912", "ENSBTAT00000021912" ] }, "reaction_10068899": { "compartment": "compartment_7660", "id": "reaction_10068899", "reactome": "R-BTA-3857336", "name": "CEBPB homodimerization", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068891" ], "products": [ "species_10068893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086463", "A0A3Q1NLC4", "ENSBTAT00000086463" ] }, "reaction_10040355": { "compartment": "compartment_70101", "id": "reaction_10040355", "reactome": "R-BTA-182594", "name": "Association of INK4 family proteins with CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040351", "species_10040345" ], "products": [ "species_10040353" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10088026": { "compartment": "compartment_984", "id": "reaction_10088026", "reactome": "R-BTA-8952251", "name": "PLA2G15 hydrolyses LPC to GPCho and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2173763" ], "products": [ "species_8954142", "species_8952253" ], "modifiers": [ [ "species_10088023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009888" ] }, "reaction_10058910": { "compartment": "compartment_12045", "id": "reaction_10058910", "reactome": "R-BTA-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1524028" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058871": { "compartment": "compartment_12045", "id": "reaction_10058871", "reactome": "R-BTA-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_975614" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10057007": { "compartment": "compartment_70101", "id": "reaction_10057007", "reactome": "R-BTA-1237042", "name": "AQP1 tetramer transports CO2 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237009" ], "products": [ "species_113528" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10081968": { "compartment": "compartment_70101", "id": "reaction_10081968", "reactome": "R-BTA-6806831", "name": "CYB5Rs reduce MetHb to HbA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081949", "species_73473" ], "products": [ "species_70106", "species_10081955", "species_29360" ], "modifiers": [ [ "species_10081965", "catalyst" ] ], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "A0A3Q1LIS5", "ENSBTAT00000068812", "A0A3Q1MXD6", "ENSBTAT00000072609" ] }, "reaction_10058790": { "compartment": "compartment_70101", "id": "reaction_10058790", "reactome": "R-BTA-1475435", "name": "CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057062": { "compartment": "compartment_70101", "id": "reaction_10057062", "reactome": "R-BTA-1237325", "name": "Hemoglobin A is protonated and carbamated causing release of oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057046", "species_70106", "species_113528" ], "products": [ "species_10057060", "species_29368" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10037739": { "compartment": "compartment_70101", "id": "reaction_10037739", "reactome": "R-BTA-140216", "name": "Translocation of PMAIP1 (NOXA) to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037735" ], "products": [ "species_10037737" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071269", "ENSBTAT00000071269" ] }, "reaction_10058985": { "compartment": "compartment_70616", "id": "reaction_10058985", "reactome": "R-BTA-1482850", "name": "MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524083", "species_1498773" ], "products": [ "species_1524072", "species_1524089" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058955": { "compartment": "compartment_70616", "id": "reaction_10058955", "reactome": "R-BTA-1482781", "name": "MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524075", "species_1498773" ], "products": [ "species_1524072", "species_1524079" ], "modifiers": [ [ "species_10058952", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079163" ] }, "reaction_10058993": { "compartment": "compartment_12045", "id": "reaction_10058993", "reactome": "R-BTA-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1524069" ], "products": [ "species_1524081", "species_76194" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10058998": { "compartment": "compartment_12045", "id": "reaction_10058998", "reactome": "R-BTA-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10035773", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076188" ] }, "reaction_10045466": { "compartment": "compartment_204883", "id": "reaction_10045466", "reactome": "R-BTA-375342", "name": "Connexin 36 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045463", "catalyst" ] ], "additional_components": [ "Q866T7", "ENSBTAT00000028966" ] }, "reaction_10045455": { "compartment": "compartment_876", "id": "reaction_10045455", "reactome": "R-BTA-375340", "name": "Connexin 62 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045452", "catalyst" ] ], "additional_components": [ "E1BLU3", "ENSBTAT00000015039" ] }, "reaction_10045444": { "compartment": "compartment_876", "id": "reaction_10045444", "reactome": "R-BTA-375339", "name": "Pannexin 1/Pannexin2 mediated neuronal gap junction communication", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_29804" ], "modifiers": [ [ "species_10045441", "catalyst" ] ], "additional_components": [ "D7R519", "ENSBTAT00000015932", "G5E5X7", "ENSBTAT00000037612" ] }, "reaction_10084238": { "compartment": "compartment_262783", "id": "reaction_10084238", "reactome": "R-BTA-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084234" ], "products": [ "species_10084236" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "G3N3N1", "ENSBTAT00000063023", "species_29438", "G3N3N1", "ENSBTAT00000063023", "species_29438", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084291": { "compartment": "compartment_5683628", "id": "reaction_10084291", "reactome": "R-BTA-8854612", "name": "TBC1D25 accelerates GTP hydrolysis by RAB33B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084286" ], "products": [ "species_29372", "species_10084288" ], "modifiers": [ [ "species_10084286", "catalyst" ], [ "species_10084272", "catalyst" ] ], "additional_components": [ "E1BJA0", "ENSBTAT00000083670", "species_29438", "E1BJA0", "ENSBTAT00000083670", "species_29420", "E1BJA0", "ENSBTAT00000083670", "species_29438", "ENSBTAT00000012236" ] }, "reaction_10084261": { "compartment": "compartment_17938", "id": "reaction_10084261", "reactome": "R-BTA-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10084252" ], "products": [ "species_29372", "species_10084254" ], "modifiers": [ [ "species_10084252", "catalyst" ], [ "species_10084259", "catalyst" ] ], "additional_components": [ "species_29438", "Q08DE8", "ENSBTAT00000016976", "Q08DE8", "ENSBTAT00000016976", "species_29420", "species_29438", "Q08DE8", "ENSBTAT00000016976", "ENSBTAT00000082752" ] }, "reaction_10084228": { "compartment": "compartment_19363", "id": "reaction_10084228", "reactome": "R-BTA-8854209", "name": "TBC1D10A binds JFC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084224", "species_10084220" ], "products": [ "species_10084226" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055485", "ENSBTAT00000077895", "A0A3Q1M443", "ENSBTAT00000077895", "F1MB46", "ENSBTAT00000055485" ] }, "reaction_10084276": { "compartment": "compartment_5683628", "id": "reaction_10084276", "reactome": "R-BTA-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084272", "species_10084268" ], "products": [ "species_10084274" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012236", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "O41515", "ENSBTAT00000015449", "Q9GJW7", "ENSBTAT00000019814", "E1BHZ5", "ENSBTAT00000012236" ] }, "reaction_10084246": { "compartment": "compartment_20699", "id": "reaction_10084246", "reactome": "R-BTA-8854303", "name": "TBC1D11 binds RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084242", "species_10083720" ], "products": [ "species_10084244" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061025", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "species_29438", "A0A3Q1MBS7", "ENSBTAT00000082349", "F1N746", "ENSBTAT00000061025" ] }, "reaction_10044801": { "compartment": "compartment_70101", "id": "reaction_10044801", "reactome": "R-BTA-350604", "name": "Agmatine + H2O <=> putrescine + urea", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_351164" ], "products": [ "species_29514", "species_29610" ], "modifiers": [ [ "species_10044798", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085149" ] }, "reaction_10041177": { "compartment": "compartment_70101", "id": "reaction_10041177", "reactome": "R-BTA-192051", "name": "CYP7A1 7-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193384", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192114" ], "modifiers": [ [ "species_10041174", "catalyst" ] ], "additional_components": [ "E1BM29", "ENSBTAT00000006957" ] }, "reaction_10041500": { "compartment": "compartment_70101", "id": "reaction_10041500", "reactome": "R-BTA-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194634", "species_29364" ], "products": [ "species_29356", "species_29366", "species_194644", "species_29460" ], "modifiers": [ [ "species_10041497", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002582" ] }, "reaction_10041206": { "compartment": "compartment_5460", "id": "reaction_10041206", "reactome": "R-BTA-192123", "name": "CYP27A1 27-hydroxylates CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_193840", "species_113600" ], "products": [ "species_113563", "species_193846", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10044232": { "compartment": "compartment_70101", "id": "reaction_10044232", "reactome": "R-BTA-211951", "name": "CYP1B1 4-hydroxylates EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193132", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_211973" ], "modifiers": [ [ "species_10044229", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075887", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10041195": { "compartment": "compartment_70101", "id": "reaction_10041195", "reactome": "R-BTA-192065", "name": "CYP7B1 7-hydroxylates 25OH-CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_192148", "species_29364" ], "products": [ "species_29356", "species_192184", "species_29366" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10043964": { "compartment": "compartment_70101", "id": "reaction_10043964", "reactome": "R-BTA-209845", "name": "CYP2R1 25-hydroxylates VD3 to 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_8963870", "species_29364" ], "products": [ "species_8963879", "species_29356", "species_29366" ], "modifiers": [ [ "species_10043961", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084891" ] }, "reaction_10044225": { "compartment": "compartment_5460", "id": "reaction_10044225", "reactome": "R-BTA-211950", "name": "CYP24A1 24-hydroxylates CTL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_215607", "species_113600" ], "products": [ "species_113563", "species_215622", "species_113521" ], "modifiers": [ [ "species_10043907", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10043971": { "compartment": "compartment_70101", "id": "reaction_10043971", "reactome": "R-BTA-209868", "name": "CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209804", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_209800", "species_29366" ], "modifiers": [ [ "species_10043968", "catalyst" ], [ "species_29532", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000022485" ] }, "reaction_10044293": { "compartment": "compartment_12045", "id": "reaction_10044293", "reactome": "R-BTA-212007", "name": "CYP26A1,B1 4-hydroxylate atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_215573", "species_113601" ], "products": [ "species_113519", "species_113564", "species_215584" ], "modifiers": [ [ "species_10044290", "catalyst" ] ], "additional_components": [ "F1MZS4", "ENSBTAT00000028140", "E1BHJ4", "ENSBTAT00000016198", "E1BDT5", "ENSBTAT00000056396" ] }, "reaction_10044280": { "compartment": "compartment_12045", "id": "reaction_10044280", "reactome": "R-BTA-212005", "name": "CYP2F1 dehydrogenates 3-methylindole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_213162", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213163" ], "modifiers": [ [ "species_10044277", "catalyst" ] ], "additional_components": [ "G3MYW0", "ENSBTAT00000063781" ] }, "reaction_10044218": { "compartment": "compartment_12045", "id": "reaction_10044218", "reactome": "R-BTA-211929", "name": "CYP2C19 5-hydroxylates omeprazole", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211892", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211944" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044250": { "compartment": "compartment_12045", "id": "reaction_10044250", "reactome": "R-BTA-211966", "name": "CYP2D6 4-hydroxylates debrisoquine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211993", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211952" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10044477": { "compartment": "compartment_12045", "id": "reaction_10044477", "reactome": "R-BTA-213175", "name": "CYP3A4,5 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_156522", "species_113601" ], "products": [ "species_113519", "species_113564", "species_156523" ], "modifiers": [ [ "species_10044474", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10044223": { "compartment": "compartment_12045", "id": "reaction_10044223", "reactome": "R-BTA-211948", "name": "CYP3A4 can N-demethylate loperamide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_213155" ], "products": [ "species_113519", "species_113564", "species_213151" ], "modifiers": [ [ "species_10044220", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10035865": { "compartment": "compartment_17960", "id": "reaction_10035865", "reactome": "R-BTA-76426", "name": "N-atom dealkylation of caffeine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_40727", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76424" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10035861": { "compartment": "compartment_17960", "id": "reaction_10035861", "reactome": "R-BTA-76373", "name": "N-hydroxylation of 4-aminobiphenyl", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_47687", "species_113601" ], "products": [ "species_113519", "species_113564", "species_34889" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10044275": { "compartment": "compartment_12045", "id": "reaction_10044275", "reactome": "R-BTA-212004", "name": "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_211939" ], "products": [ "species_113519", "species_113564", "species_211927" ], "modifiers": [ [ "species_10044272", "catalyst" ] ], "additional_components": [ "F1MRH2", "ENSBTAT00000040300" ] }, "reaction_10044182": { "compartment": "compartment_12045", "id": "reaction_10044182", "reactome": "R-BTA-211882", "name": "CYP3A7 can 6beta-hydroxylate testosterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_30321", "species_113601" ], "products": [ "species_113519", "species_113564", "species_213144" ], "modifiers": [ [ "species_10044179", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ03", "ENSBTAT00000067793", "G3X6I4", "ENSBTAT00000016177", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10035977": { "compartment": "compartment_12045", "id": "reaction_10035977", "reactome": "R-BTA-76472", "name": "Ethylene is oxidized to Ethylene oxide by CYP1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_38985", "species_113601" ], "products": [ "species_113519", "species_113564", "species_38987" ], "modifiers": [ [ "species_10035962", "catalyst" ], [ "species_10035975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061300", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10044265": { "compartment": "compartment_12045", "id": "reaction_10044265", "reactome": "R-BTA-211988", "name": "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211855", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211937" ], "modifiers": [ [ "species_10044262", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159" ] }, "reaction_10044204": { "compartment": "compartment_12045", "id": "reaction_10044204", "reactome": "R-BTA-211910", "name": "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211906", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211894" ], "modifiers": [ [ "species_10044201", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "F1MEU8", "ENSBTAT00000008918" ] }, "reaction_10044270": { "compartment": "compartment_12045", "id": "reaction_10044270", "reactome": "R-BTA-211991", "name": "Cyclophosphamide is 4-hydroxylated by CYP2B6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_211977", "species_113601" ], "products": [ "species_113519", "species_113564", "species_211967" ], "modifiers": [ [ "species_10044267", "catalyst" ] ], "additional_components": [ "A0A3Q1MU42", "ENSBTAT00000079854" ] }, "reaction_10044167": { "compartment": "compartment_12045", "id": "reaction_10044167", "reactome": "R-BTA-211881", "name": "Coumarin is 7-hydroxylated by CYP2A13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10044164", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10035911": { "compartment": "compartment_12045", "id": "reaction_10035911", "reactome": "R-BTA-76456", "name": "O-atom dealkylation of dextromethorphan", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_39703", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_76455" ], "modifiers": [ [ "species_10035908", "catalyst" ] ], "additional_components": [ "Q2KJJ2", "ENSBTAT00000000869" ] }, "reaction_10035878": { "compartment": "compartment_12045", "id": "reaction_10035878", "reactome": "R-BTA-76453", "name": "Coumarin is 7-hydroxylated by CYP2A6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76328", "species_113601" ], "products": [ "species_113519", "species_113564", "species_76452" ], "modifiers": [ [ "species_10035875", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779" ] }, "reaction_10059035": { "compartment": "compartment_12045", "id": "reaction_10059035", "reactome": "R-BTA-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_1500581", "species_109395" ], "modifiers": [ [ "species_10059032", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "Q17QM4", "ENSBTAT00000010310" ] }, "reaction_10059082": { "compartment": "compartment_70101", "id": "reaction_10059082", "reactome": "R-BTA-1483096", "name": "PETA is dephosphorylated to ETA by PHOSPHO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_428686" ], "products": [ "species_29372", "species_1498751" ], "modifiers": [ [ "species_10059079", "catalyst" ] ], "additional_components": [ "species_29926", "E1BCN8", "ENSBTAT00000000037" ] }, "reaction_10059130": { "compartment": "compartment_12045", "id": "reaction_10059130", "reactome": "R-BTA-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428686", "species_110614" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10059127", "catalyst" ] ], "additional_components": [ "A0A3Q1MLB5", "ENSBTAT00000070509" ] }, "reaction_10059150": { "compartment": "compartment_70101", "id": "reaction_10059150", "reactome": "R-BTA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10059147", "catalyst" ] ], "additional_components": [ "F1MRD9", "ENSBTAT00000024637", "A0A3Q1LRY5", "ENSBTAT00000082323", "A0A3Q1MPV1", "ENSBTAT00000074052" ] }, "reaction_10076994": { "compartment": "compartment_5460", "id": "reaction_10076994", "reactome": "R-BTA-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696414", "species_113521" ], "products": [ "species_113548", "species_113532", "species_5693978" ], "modifiers": [ [ "species_10076991", "catalyst" ] ], "additional_components": [ "Q5E9S4", "ENSBTAT00000013587" ] }, "reaction_10077004": { "compartment": "compartment_12045", "id": "reaction_10077004", "reactome": "R-BTA-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10058892": { "compartment": "compartment_12045", "id": "reaction_10058892", "reactome": "R-BTA-1482647", "name": "2-MAG and DAG are transacylated to TAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_1500596" ], "products": [ "species_76116", "species_1500594" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10059006": { "compartment": "compartment_12045", "id": "reaction_10059006", "reactome": "R-BTA-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10035835", "catalyst" ] ], "additional_components": [ "F1MIW3", "ENSBTAT00000037423" ] }, "reaction_10058894": { "compartment": "compartment_12045", "id": "reaction_10058894", "reactome": "R-BTA-1482654", "name": "2-MAG is transacylated to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728" ], "products": [ "species_76116", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058961": { "compartment": "compartment_12045", "id": "reaction_10058961", "reactome": "R-BTA-1482811", "name": "DAG is hydrolyzed to 2-MAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500596" ], "products": [ "species_1498728", "species_1524021" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10058819": { "compartment": "compartment_12045", "id": "reaction_10058819", "reactome": "R-BTA-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_1500593", "species_76116" ], "modifiers": [ [ "species_10058816", "catalyst" ] ], "additional_components": [ "A0A3Q1LUK0", "ENSBTAT00000073448" ] }, "reaction_10058948": { "compartment": "compartment_12045", "id": "reaction_10058948", "reactome": "R-BTA-1482777", "name": "TAG is hydrolyzed to DAG by PNPLA2/3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500594" ], "products": [ "species_1524021", "species_1500596" ], "modifiers": [ [ "species_10058889", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004368" ] }, "reaction_10083572": { "compartment": "compartment_12045", "id": "reaction_10083572", "reactome": "R-BTA-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_1500594", "species_76194" ], "modifiers": [ [ "species_10083569", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010259" ] }, "reaction_10038938": { "compartment": "compartment_7660", "id": "reaction_10038938", "reactome": "R-BTA-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038932", "species_164121" ], "products": [ "species_10038936" ], "modifiers": [], "additional_components": [ "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "F1MQV7", "ENSBTAT00000024965", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "species_76577" ] }, "reaction_10083614": { "compartment": "compartment_984", "id": "reaction_10083614", "reactome": "R-BTA-8848663", "name": "ADIPOQ trimer binds ADIPOR dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083610", "species_10083594" ], "products": [ "species_10083612" ], "modifiers": [], "additional_components": [ "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795", "Q3T0U4", "ENSBTAT00000040283", "Q32KM7", "ENSBTAT00000011923", "A0A3Q1M564", "ENSBTAT00000077795" ] }, "reaction_10060553": { "compartment": "compartment_172574", "id": "reaction_10060553", "reactome": "R-BTA-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060537": { "compartment": "compartment_172574", "id": "reaction_10060537", "reactome": "R-BTA-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_1806198", "species_29370" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060468": { "compartment": "compartment_172574", "id": "reaction_10060468", "reactome": "R-BTA-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_29372", "species_1806195" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10088526": { "compartment": "compartment_5460", "id": "reaction_10088526", "reactome": "R-BTA-8952903", "name": "ADPRHL2 hydrolyses poly(ADP-ribose)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8952909", "species_113521" ], "products": [ "species_8952909", "species_8952905" ], "modifiers": [ [ "species_10088523", "catalyst" ] ], "additional_components": [ "species_8870342", "species_8870342", "ENSBTAT00000028950" ] }, "reaction_10037674": { "compartment": "compartment_70101", "id": "reaction_10037674", "reactome": "R-BTA-139899", "name": "Sequestration of BAD protein by 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10037644" ], "products": [ "species_10037672" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000016610", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10037678": { "compartment": "compartment_70101", "id": "reaction_10037678", "reactome": "R-BTA-139905", "name": "Translocation of activated BAD protein to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037676" ], "products": [ "species_10037626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "ENSBTAT00000016610" ] }, "reaction_10037630": { "compartment": "compartment_17906", "id": "reaction_10037630", "reactome": "R-BTA-139897", "name": "BAD displaces tBID from BCL-2 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037626", "species_10037275" ], "products": [ "species_10037269", "species_10037628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016610", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737", "ENSBTAT00000042737", "F6R2C4", "ENSBTAT00000025701", "F1MUT9", "ENSBTAT00000016610" ] }, "reaction_10047900": { "compartment": "compartment_114521", "id": "reaction_10047900", "reactome": "R-BTA-418365", "name": "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427899", "species_74016" ], "products": [ "species_70106", "species_139827" ], "modifiers": [ [ "species_10047897", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078158" ] }, "reaction_10076824": { "compartment": "compartment_17906", "id": "reaction_10076824", "reactome": "R-BTA-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696066", "species_5696069" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10076821", "catalyst" ] ], "additional_components": [ "species_6814795", "species_6797635", "species_1524101", "species_417891", "A0A3Q1MFM9", "ENSBTAT00000074114", "species_29926" ] }, "reaction_10085340": { "compartment": "compartment_70101", "id": "reaction_10085340", "reactome": "R-BTA-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_1602448" ], "products": [ "species_426755", "species_426658" ], "modifiers": [ [ "species_10085337", "catalyst" ] ], "additional_components": [ "E1B9I9", "ENSBTAT00000013851", "A0A3Q1MUM3", "ENSBTAT00000079883", "A0A3Q1N293", "ENSBTAT00000069345" ] }, "reaction_10059091": { "compartment": "compartment_12045", "id": "reaction_10059091", "reactome": "R-BTA-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_111294", "species_426955" ], "modifiers": [ [ "species_10059088", "catalyst" ] ], "additional_components": [ "species_29926", "G3MZU2", "ENSBTAT00000065725" ] }, "reaction_10059044": { "compartment": "compartment_12045", "id": "reaction_10059044", "reactome": "R-BTA-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_426639", "species_109395" ], "modifiers": [ [ "species_10059041", "catalyst" ] ], "additional_components": [ "Q3T103", "ENSBTAT00000010454", "species_29926", "species_113527" ] }, "reaction_10071344": { "compartment": "compartment_876", "id": "reaction_10071344", "reactome": "R-BTA-5333678", "name": "CPNEs bind PL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071340", "species_171142" ], "products": [ "species_10071342" ], "modifiers": [ [ "species_74016", "catalyst" ] ], "additional_components": [ "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644", "species_171142", "Q2KHY1", "ENSBTAT00000002436", "A5PJY9", "ENSBTAT00000020644" ] }, "reaction_10059849": { "compartment": "compartment_984", "id": "reaction_10059849", "reactome": "R-BTA-1602374", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[15]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_33625" ], "products": [ "species_1602419", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058943": { "compartment": "compartment_12045", "id": "reaction_10058943", "reactome": "R-BTA-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058940", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10085310": { "compartment": "compartment_12045", "id": "reaction_10085310", "reactome": "R-BTA-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_392417", "species_1500646" ], "products": [ "species_33625", "species_1806234" ], "modifiers": [ [ "species_10085307", "catalyst" ] ], "additional_components": [ "A0A3Q1MI45", "ENSBTAT00000070851", "F1MFD9", "ENSBTAT00000012114", "A0A3Q1LWY5", "ENSBTAT00000073265" ] }, "reaction_10058945": { "compartment": "compartment_12045", "id": "reaction_10058945", "reactome": "R-BTA-1482776", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1524021", "species_1498724" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058880": { "compartment": "compartment_12045", "id": "reaction_10058880", "reactome": "R-BTA-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498724" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10058916": { "compartment": "compartment_12045", "id": "reaction_10058916", "reactome": "R-BTA-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498722" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10058800", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054491" ] }, "reaction_10059014": { "compartment": "compartment_12045", "id": "reaction_10059014", "reactome": "R-BTA-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1500646" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059016": { "compartment": "compartment_12045", "id": "reaction_10059016", "reactome": "R-BTA-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058855", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "A0A3Q1MFE1", "ENSBTAT00000078105" ] }, "reaction_10059018": { "compartment": "compartment_12045", "id": "reaction_10059018", "reactome": "R-BTA-1482907", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1524021", "species_1498740" ], "modifiers": [ [ "species_10058905", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570" ] }, "reaction_10058826": { "compartment": "compartment_70616", "id": "reaction_10058826", "reactome": "R-BTA-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10059021": { "compartment": "compartment_12045", "id": "reaction_10059021", "reactome": "R-BTA-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10059011", "catalyst" ] ], "additional_components": [ "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10058877": { "compartment": "compartment_12045", "id": "reaction_10058877", "reactome": "R-BTA-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058812": { "compartment": "compartment_12045", "id": "reaction_10058812", "reactome": "R-BTA-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1498740" ], "products": [ "species_1483256", "species_76194" ], "modifiers": [ [ "species_10035781", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001250" ] }, "reaction_10058913": { "compartment": "compartment_70616", "id": "reaction_10058913", "reactome": "R-BTA-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_29374", "species_1524042" ], "modifiers": [ [ "species_10058823", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000072" ] }, "reaction_10058983": { "compartment": "compartment_70616", "id": "reaction_10058983", "reactome": "R-BTA-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524047", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10059847": { "compartment": "compartment_984", "id": "reaction_10059847", "reactome": "R-BTA-1602368", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1602402" ], "products": [ "species_1602415", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10058934": { "compartment": "compartment_70616", "id": "reaction_10058934", "reactome": "R-BTA-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524027", "species_1524085" ], "modifiers": [ [ "species_10058931", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227" ] }, "reaction_10058809": { "compartment": "compartment_12045", "id": "reaction_10058809", "reactome": "R-BTA-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_975614" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058970": { "compartment": "compartment_12045", "id": "reaction_10058970", "reactome": "R-BTA-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058967", "catalyst" ] ], "additional_components": [ "species_74016", "Q56JZ2", "ENSBTAT00000007570", "E1BE78", "ENSBTAT00000017658" ] }, "reaction_10058829": { "compartment": "compartment_12045", "id": "reaction_10058829", "reactome": "R-BTA-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_426925", "species_76194" ], "modifiers": [ [ "species_10058806", "catalyst" ] ], "additional_components": [ "A0A3Q1MPE0", "ENSBTAT00000079571", "G8JL05", "ENSBTAT00000054491", "F1MTK4", "ENSBTAT00000001250", "F1MH02", "ENSBTAT00000010729" ] }, "reaction_10058990": { "compartment": "compartment_12045", "id": "reaction_10058990", "reactome": "R-BTA-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10058987", "catalyst" ] ], "additional_components": [ "A0A3Q1NMD6", "ENSBTAT00000078451", "A0A3Q1LR65", "ENSBTAT00000067227", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059856": { "compartment": "compartment_984", "id": "reaction_10059856", "reactome": "R-BTA-1602399", "name": "PC is hydrolyzed to 1-acyl LPC by PLB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10054379", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076923" ] }, "reaction_10059858": { "compartment": "compartment_984", "id": "reaction_10059858", "reactome": "R-BTA-1602417", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[16]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_429802" ], "products": [ "species_1602390", "species_1602366" ], "modifiers": [ [ "species_10059844", "catalyst" ] ], "additional_components": [ "species_74016", "F1MSG5", "ENSBTAT00000005791", "E1BGU4", "ENSBTAT00000028684", "Q56JZ2", "ENSBTAT00000007570", "A0A3Q1MFE1", "ENSBTAT00000078105", "A5D7L0", "ENSBTAT00000020263", "A0A3Q1MNU5", "ENSBTAT00000080344", "A0A3Q1M5P6", "ENSBTAT00000077544" ] }, "reaction_10085826": { "compartment": "compartment_12045", "id": "reaction_10085826", "reactome": "R-BTA-8874435", "name": "THEM86B hydrolyses PMCHO, PMETAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8874447" ], "products": [ "species_8874450", "species_5696116" ], "modifiers": [ [ "species_10085823", "catalyst" ] ], "additional_components": [ "CHEBI:17810", "CHEBI:17476", "CHEBI:36313", "CHEBI:36314", "ENSBTAT00000076823" ] }, "reaction_10058996": { "compartment": "compartment_12045", "id": "reaction_10058996", "reactome": "R-BTA-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426925" ], "products": [ "species_1524021", "species_975614" ], "modifiers": [ [ "species_10058868", "catalyst" ] ], "additional_components": [ "A0A3Q1LR65", "ENSBTAT00000067227", "A0A3Q1LYR5", "ENSBTAT00000078489", "F1MG30", "ENSBTAT00000003576", "F1MNU5", "ENSBTAT00000006775" ] }, "reaction_10059121": { "compartment": "compartment_12045", "id": "reaction_10059121", "reactome": "R-BTA-1483186", "name": "PC is converted to PS by PTDSS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_200736" ], "products": [ "species_264618", "species_1500646" ], "modifiers": [ [ "species_10059118", "catalyst" ] ], "additional_components": [ "ENSBTAT00000018461" ] }, "reaction_10059073": { "compartment": "compartment_12045", "id": "reaction_10059073", "reactome": "R-BTA-1483089", "name": "PE is converted to PS by PTDSS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_1500581" ], "products": [ "species_1498751", "species_1500646" ], "modifiers": [ [ "species_10059070", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077015" ] }, "reaction_10059101": { "compartment": "compartment_70616", "id": "reaction_10059101", "reactome": "R-BTA-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524101", "species_110577" ], "products": [ "species_159450", "species_1524064" ], "modifiers": [ [ "species_10059098", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007970" ] }, "reaction_10057390": { "compartment": "compartment_876", "id": "reaction_10057390", "reactome": "R-BTA-1296043", "name": "Activation of HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057387", "catalyst" ] ], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10057607": { "compartment": "compartment_876", "id": "reaction_10057607", "reactome": "R-BTA-1297444", "name": "Binding of cAMP to HCN channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10057385" ], "products": [ "species_10057387" ], "modifiers": [], "additional_components": [ "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "E1BM97", "ENSBTAT00000061021", "E1BL87", "ENSBTAT00000022679", "E1BIS4", "ENSBTAT00000023219", "species_30389" ] }, "reaction_10049326": { "compartment": "compartment_876", "id": "reaction_10049326", "reactome": "R-BTA-433104", "name": "NACT co-transports trivalent citrate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433138", "species_74113" ], "products": [ "species_76190", "species_83910" ], "modifiers": [ [ "species_10049323", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006144" ] }, "reaction_10049333": { "compartment": "compartment_876", "id": "reaction_10049333", "reactome": "R-BTA-433114", "name": "NaS1 co-transports sulphate and a sodium ion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_74113" ], "products": [ "species_83910", "species_174375" ], "modifiers": [ [ "species_10049330", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078998" ] }, "reaction_10051305": { "compartment": "compartment_876", "id": "reaction_10051305", "reactome": "R-BTA-561041", "name": "OAT1-3 transport organic anions with antiport of dicarboxylic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_561049" ], "products": [ "species_561078", "species_561075" ], "modifiers": [ [ "species_10051302", "catalyst" ] ], "additional_components": [ "CHEBI:104011", "species_561052", "species_561052", "CHEBI:104011", "F1MIJ1", "ENSBTAT00000018132", "G3N1R8", "ENSBTAT00000064695", "F1MII8", "ENSBTAT00000018139" ] }, "reaction_10051314": { "compartment": "compartment_876", "id": "reaction_10051314", "reactome": "R-BTA-561253", "name": "SLC22A12 exchanges extracellular urate for cytosolic LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_429056" ], "products": [ "species_373863", "species_30034" ], "modifiers": [ [ "species_10051311", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068956" ] }, "reaction_10051307": { "compartment": "compartment_876", "id": "reaction_10051307", "reactome": "R-BTA-561054", "name": "OCT2 mediates tubular secretion of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549266" ], "products": [ "species_549237" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051325": { "compartment": "compartment_876", "id": "reaction_10051325", "reactome": "R-BTA-597628", "name": "SLC22A18 exchanges extracellular organic cations for cytosolic H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_597604", "species_70106" ], "products": [ "species_351626", "species_597623" ], "modifiers": [ [ "species_10051322", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016935" ] }, "reaction_10051276": { "compartment": "compartment_876", "id": "reaction_10051276", "reactome": "R-BTA-549241", "name": "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549261", "species_74113" ], "products": [ "species_83910", "species_549260" ], "modifiers": [ [ "species_10051273", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013203" ] }, "reaction_10051283": { "compartment": "compartment_876", "id": "reaction_10051283", "reactome": "R-BTA-549279", "name": "OCT2 mediates tubular uptake of organic cations in the kidney", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549237" ], "products": [ "species_549266" ], "modifiers": [ [ "species_10045416", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "CHEBI:31941", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_209789", "CHEBI:65133", "species_351164", "species_390899", "species_264638", "species_549282", "species_209914", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:6801", "species_549282", "CHEBI:16737", "species_264638", "CHEBI:65133", "CHEBI:641", "species_209914", "species_351164", "species_390899", "CHEBI:31941", "species_209789", "E1BHW6", "ENSBTAT00000012607", "ENSBTAT00000055483" ] }, "reaction_10051269": { "compartment": "compartment_876", "id": "reaction_10051269", "reactome": "R-BTA-549129", "name": "OCT1 transports organic cations into hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549264" ], "products": [ "species_549250" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10051286": { "compartment": "compartment_876", "id": "reaction_10051286", "reactome": "R-BTA-549322", "name": "OCT1 transports organic cations out of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549250" ], "products": [ "species_549264" ], "modifiers": [ [ "species_10051266", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "CHEBI:46020", "CHEBI:42820", "CHEBI:6801", "species_549282", "species_264638", "CHEBI:65133", "CHEBI:15854", "species_204635", "CHEBI:641", "species_390899", "species_353560", "species_209789", "CHEBI:42820", "CHEBI:641", "CHEBI:46020", "species_159362", "CHEBI:6801", "CHEBI:28918", "species_204635", "CHEBI:15854", "species_209789", "CHEBI:65133", "species_390899", "species_353560", "species_264638", "species_549282", "A7MBE0", "ENSBTAT00000004059" ] }, "reaction_10067993": { "compartment": "compartment_7660", "id": "reaction_10067993", "reactome": "R-BTA-3371537", "name": "DBC1 binds SIRT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048710", "species_10067989" ], "products": [ "species_10067991" ], "modifiers": [], "additional_components": [ "ENSBTAT00000018630", "ENSBTAT00000007194", "E1B9H3", "ENSBTAT00000007194", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10071241": { "compartment": "compartment_70101", "id": "reaction_10071241", "reactome": "R-BTA-5251959", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10071123" ], "products": [ "species_29372", "species_10071232" ], "modifiers": [ [ "species_10071238", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q27975", "ENSBTAT00000017500", "species_29370", "Q3MI00", "ENSBTAT00000036270", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437" ] }, "reaction_10068008": { "compartment": "compartment_7660", "id": "reaction_10068008", "reactome": "R-BTA-3371567", "name": "DBC1 is phosphorylated by ATM/ART", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10067995" ], "products": [ "species_113582", "species_10067989" ], "modifiers": [ [ "species_10068005", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007194", "ENSBTAT00000007194", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1M8V1", "ENSBTAT00000066572" ] }, "reaction_10071208": { "compartment": "compartment_7660", "id": "reaction_10071208", "reactome": "R-BTA-5251955", "name": "HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10071171" ], "products": [ "species_113550", "species_10071169", "species_10071195" ], "modifiers": [ [ "species_10071205", "catalyst" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "Q56JY0", "ENSBTAT00000026632", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_29370", "Q1RMH9", "ENSBTAT00000004925", "F1N7H0", "ENSBTAT00000003437", "Q3MI00", "ENSBTAT00000036270" ] }, "reaction_10071313": { "compartment": "compartment_70101", "id": "reaction_10071313", "reactome": "R-BTA-5252079", "name": "HSP110s exchange ATP for ADP on HSP70s:ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071232", "species_113592" ], "products": [ "species_10071123", "species_29370" ], "modifiers": [ [ "species_10071304", "catalyst" ], [ "species_10071311", "inhibitor" ] ], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_29370", "Q27975", "ENSBTAT00000017500", "species_113592", "Q0IIM3", "ENSBTAT00000006600", "Q148J7", "ENSBTAT00000023720", "Q3ZBG5", "ENSBTAT00000007039", "F1MIU2", "ENSBTAT00000018131", "F1MSS9", "ENSBTAT00000017468", "A0A3Q1MQM3", "ENSBTAT00000074682" ] }, "reaction_10071127": { "compartment": "compartment_70101", "id": "reaction_10071127", "reactome": "R-BTA-5251942", "name": "Hikeshi binds HSP70s:ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10071123", "species_10071069" ], "products": [ "species_10071125" ], "modifiers": [], "additional_components": [ "Q27975", "ENSBTAT00000017500", "species_113592", "ENSBTAT00000026632", "Q56JY0", "ENSBTAT00000026632", "Q27975", "ENSBTAT00000017500", "species_113592" ] }, "reaction_10092312": { "compartment": "compartment_70616", "id": "reaction_10092312", "reactome": "R-BTA-9709406", "name": "CO binds to Cytochrome c oxidase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9709326", "species_10038606" ], "products": [ "species_10038645" ], "modifiers": [], "additional_components": [ "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "E1BH77", "ENSBTAT00000006474", "P68530", "ENSBTAT00000060549", "A0A3Q1LKB8", "ENSBTAT00000080485", "Q6QTG5", "ENSBTAT00000060566", "A0A3Q1MBD7", "ENSBTAT00000076309", "Q6QTG9", "ENSBTAT00000060569", "A0A3Q1MB49", "ENSBTAT00000067651", "CHEBI:28694", "Q01321", "ENSBTAT00000014801", "P00426", "ENSBTAT00000022949", "P00430", "ENSBTAT00000079150", "P00423", "ENSBTAT00000053881", "P13182", "ENSBTAT00000071537", "Q3T061", "ENSBTAT00000000943", "species_9709335" ] }, "reaction_10040636": { "compartment": "compartment_70101", "id": "reaction_10040636", "reactome": "R-BTA-189398", "name": "HMOX1 dimer, HMOX2 cleave heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364", "species_71185" ], "products": [ "species_29356", "species_189385", "species_71067", "species_189396", "species_29366" ], "modifiers": [ [ "species_10040633", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047056" ] }, "reaction_10047807": { "compartment": "compartment_7660", "id": "reaction_10047807", "reactome": "R-BTA-400143", "name": "Fatty acid ligands activate PPARA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047799", "species_10047793", "species_10047777" ], "products": [ "species_10047797", "species_10047805", "species_10047771" ], "modifiers": [], "additional_components": [ "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "P80425", "ENSBTAT00000024032", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068", "B7TCI5", "ENSBTAT00000084466", "Q5EA13", "ENSBTAT00000068423", "A0A3Q1MSZ9", "ENSBTAT00000087441", "ENSBTAT00000024032", "species_426576", "species_2026977", "species_2046056", "species_2046044", "species_140356", "Q5EA13", "ENSBTAT00000068423", "B7TCI5", "ENSBTAT00000084466", "A0A3Q1MSZ9", "ENSBTAT00000087441", "G3N0C2", "ENSBTAT00000064008", "Q0II51", "ENSBTAT00000078286", "F1N1K9", "ENSBTAT00000007749", "A0A3Q1LQR4", "ENSBTAT00000066577", "species_159151", "F1MD32", "ENSBTAT00000005092", "F1MTR3", "ENSBTAT00000013167", "F1MGM4", "ENSBTAT00000061343", "F1N0W0", "ENSBTAT00000023086", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10092308": { "compartment": "compartment_984", "id": "reaction_10092308", "reactome": "R-BTA-9709317", "name": "CO binds to free ferrohemoglobin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10092210", "species_9709335" ], "products": [ "species_10092212" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_9709335", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10092310": { "compartment": "compartment_984", "id": "reaction_10092310", "reactome": "R-BTA-9709360", "name": "H2O2 reduces MetHb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_351629" ], "products": [ "species_109276", "species_10092210", "species_352327" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323" ] }, "reaction_10067416": { "compartment": "compartment_70101", "id": "reaction_10067416", "reactome": "R-BTA-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067409" ], "products": [ "species_10067413", "species_10067395" ], "modifiers": [ [ "species_10067409", "catalyst" ] ], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_29426", "species_3299744", "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10056408": { "compartment": "compartment_1222693", "id": "reaction_10056408", "reactome": "R-BTA-1222376", "name": "NOX2 generates superoxide from oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_29364" ], "products": [ "species_70106", "species_1222424", "species_29366" ], "modifiers": [ [ "species_10056405", "catalyst" ] ], "additional_components": [ "A0A452DHY1", "ENSBTAT00000004279", "A0A3Q1MTW8", "ENSBTAT00000076657", "A0A3Q1MKI4", "ENSBTAT00000084691", "species_71185", "O46521", "ENSBTAT00000067849", "species_113596" ] }, "reaction_10076891": { "compartment": "compartment_5460", "id": "reaction_10076891", "reactome": "R-BTA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696199", "species_113521" ], "products": [ "species_5696194", "species_113573" ], "modifiers": [ [ "species_10076888", "catalyst" ] ], "additional_components": [ "ENSBTAT00000045076" ] }, "reaction_10087866": { "compartment": "compartment_70101", "id": "reaction_10087866", "reactome": "R-BTA-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068573" ], "products": [ "species_10067409" ], "modifiers": [], "additional_components": [ "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067388": { "compartment": "compartment_984", "id": "reaction_10067388", "reactome": "R-BTA-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_3299686" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10067385", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10068575": { "compartment": "compartment_70101", "id": "reaction_10068575", "reactome": "R-BTA-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067407", "species_10068571" ], "products": [ "species_10068573" ], "modifiers": [], "additional_components": [ "species_29426", "F1MNQ4", "ENSBTAT00000039344", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "E1BE86", "ENSBTAT00000005683", "species_3299744", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10069854": { "compartment": "compartment_17963", "id": "reaction_10069854", "reactome": "R-BTA-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069852" ], "products": [ "species_10067385" ], "modifiers": [], "additional_components": [ "F6R4N7", "ENSBTAT00000018580", "species_29426", "species_209799", "species_29426", "species_209799", "F6R4N7", "ENSBTAT00000018580" ] }, "reaction_10067731": { "compartment": "compartment_5460", "id": "reaction_10067731", "reactome": "R-BTA-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_1655882", "species_113600" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10067728", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10080786": { "compartment": "compartment_984", "id": "reaction_10080786", "reactome": "R-BTA-6799695", "name": "GPX5,6 reduce H2O2 to H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351629", "species_1247892" ], "products": [ "species_109276", "species_3341331" ], "modifiers": [ [ "species_10080783", "catalyst" ] ], "additional_components": [ "A0A3Q1M7E3", "ENSBTAT00000068263", "F1MCF5", "ENSBTAT00000015939" ] }, "reaction_10067735": { "compartment": "compartment_70616", "id": "reaction_10067735", "reactome": "R-BTA-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10038548" ], "products": [ "species_10038546", "species_189461" ], "modifiers": [], "additional_components": [ "P62894", "ENSBTAT00000007918", "CHEBI:38574", "CHEBI:38573", "P62894", "ENSBTAT00000007918" ] }, "reaction_10034166": { "compartment": "compartment_70101", "id": "reaction_10034166", "reactome": "R-BTA-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29450", "species_29366" ], "modifiers": [ [ "species_10034163", "catalyst" ] ], "additional_components": [ "E1BKZ1", "ENSBTAT00000009363", "species_113596" ] }, "reaction_10067722": { "compartment": "compartment_5460", "id": "reaction_10067722", "reactome": "R-BTA-3322995", "name": "PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_1614617" ], "products": [ "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067719", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "P35705", "ENSBTAT00000011505", "Q9BGI1", "ENSBTAT00000011403" ] }, "reaction_10068716": { "compartment": "compartment_17927", "id": "reaction_10068716", "reactome": "R-BTA-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10068713", "catalyst" ] ], "additional_components": [ "species_209799", "species_29426", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10067375": { "compartment": "compartment_5460", "id": "reaction_10067375", "reactome": "R-BTA-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_3299683" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10067372", "catalyst" ] ], "additional_components": [ "E1BHL1", "ENSBTAT00000008569", "species_113527" ] }, "reaction_10067744": { "compartment": "compartment_70101", "id": "reaction_10067744", "reactome": "R-BTA-3343700", "name": "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_29408" ], "products": [ "species_29356", "species_111745" ], "modifiers": [ [ "species_10067741", "catalyst" ] ], "additional_components": [ "O77834", "ENSBTAT00000006383", "A0A3Q1LMV5", "ENSBTAT00000084460" ] }, "reaction_10068578": { "compartment": "compartment_5460", "id": "reaction_10068578", "reactome": "R-BTA-3697894", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_3697881" ], "products": [ "species_3697842", "species_10067705", "species_113521" ], "modifiers": [ [ "species_10067717", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000000014", "ENSBTAT00000011403" ] }, "reaction_10067398": { "compartment": "compartment_70101", "id": "reaction_10067398", "reactome": "R-BTA-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29368", "species_29408" ], "modifiers": [ [ "species_10067395", "catalyst" ] ], "additional_components": [ "species_29426", "species_209799", "F1MNQ4", "ENSBTAT00000039344" ] }, "reaction_10066873": { "compartment": "compartment_7660", "id": "reaction_10066873", "reactome": "R-BTA-3239019", "name": "Active p38 MAPK phosphorylates MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066855", "species_29358" ], "products": [ "species_113582", "species_10066867" ], "modifiers": [ [ "species_10066855", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013" ] }, "reaction_10066779": { "compartment": "compartment_7660", "id": "reaction_10066779", "reactome": "R-BTA-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_113671" ], "products": [ "species_10066770", "species_159939" ], "modifiers": [ [ "species_10066776", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10066876": { "compartment": "compartment_7660", "id": "reaction_10066876", "reactome": "R-BTA-3240295", "name": "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10066770" ], "products": [ "species_77502", "species_10066768" ], "modifiers": [ [ "species_10044327", "catalyst" ] ], "additional_components": [ "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "Q3SZ25", "ENSBTAT00000010324", "A0A3Q1MSK4", "ENSBTAT00000084115", "A0A3Q1M792", "ENSBTAT00000077887", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10066832": { "compartment": "compartment_7660", "id": "reaction_10066832", "reactome": "R-BTA-3229089", "name": "PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066768", "species_10066828" ], "products": [ "species_10066830" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BFG7", "ENSBTAT00000006041", "A0A3Q1MBA7", "ENSBTAT00000073548", "Q32KX7", "ENSBTAT00000073960", "F1MKU2", "ENSBTAT00000061326", "A0A3Q1MDR6", "ENSBTAT00000076497", "A0A3Q1MCA3", "ENSBTAT00000074913", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179" ] }, "reaction_10066857": { "compartment": "compartment_7660", "id": "reaction_10066857", "reactome": "R-BTA-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10066853" ], "products": [ "species_113582", "species_10066855" ], "modifiers": [ [ "species_10050216", "catalyst" ] ], "additional_components": [ "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "F1MH23", "ENSBTAT00000012303", "G3X793", "ENSBTAT00000022358", "A0A3Q1LTT9", "ENSBTAT00000073013", "ENSBTAT00000081307" ] }, "reaction_10066786": { "compartment": "compartment_70101", "id": "reaction_10066786", "reactome": "R-BTA-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10050233" ], "products": [ "species_10050214", "species_29370" ], "modifiers": [ [ "species_10066783", "catalyst" ] ], "additional_components": [ "ENSBTAT00000081307", "ENSBTAT00000081307", "ENSBTAT00000011949" ] }, "reaction_10088964": { "compartment": "compartment_7660", "id": "reaction_10088964", "reactome": "R-BTA-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066774", "species_111793" ], "products": [ "species_10066776" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063022", "species_71067", "G3N346", "ENSBTAT00000063022" ] }, "reaction_10076298": { "compartment": "compartment_7660", "id": "reaction_10076298", "reactome": "R-BTA-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074450" ], "products": [ "species_113582", "species_10076295", "species_10074441" ], "modifiers": [ [ "species_10074450", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10074429": { "compartment": "compartment_7660", "id": "reaction_10074429", "reactome": "R-BTA-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074417", "species_10074425" ], "products": [ "species_10074427" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074431": { "compartment": "compartment_7660", "id": "reaction_10074431", "reactome": "R-BTA-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_3785706" ], "products": [ "species_10074417" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074446": { "compartment": "compartment_7660", "id": "reaction_10074446", "reactome": "R-BTA-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074438", "species_29358" ], "products": [ "species_113582", "species_10074443", "species_10074441" ], "modifiers": [ [ "species_10074438", "catalyst" ] ], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10078369": { "compartment": "compartment_7660", "id": "reaction_10078369", "reactome": "R-BTA-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074427" ], "products": [ "species_10074438", "species_2485002" ], "modifiers": [ [ "species_10074427", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10074453": { "compartment": "compartment_7660", "id": "reaction_10074453", "reactome": "R-BTA-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10074448" ], "products": [ "species_2485002", "species_10074450" ], "modifiers": [ [ "species_10074448", "catalyst" ] ], "additional_components": [ "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10069684": { "compartment": "compartment_7660", "id": "reaction_10069684", "reactome": "R-BTA-4647593", "name": "EP400 binds CDKN1A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069680", "species_10069676" ], "products": [ "species_10069682" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000027216", "F1MLB1", "ENSBTAT00000027216", "P67939", "ENSBTAT00000001420" ] }, "reaction_10076343": { "compartment": "compartment_7660", "id": "reaction_10076343", "reactome": "R-BTA-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074425" ], "products": [ "species_10074448" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104" ] }, "reaction_10068854": { "compartment": "compartment_7660", "id": "reaction_10068854", "reactome": "R-BTA-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035718", "species_75165" ], "products": [ "species_10068852" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10066630": { "compartment": "compartment_7660", "id": "reaction_10066630", "reactome": "R-BTA-3209159", "name": "Phosphorylated ERF translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066626" ], "products": [ "species_10066628" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000437", "ENSBTAT00000000437" ] }, "reaction_10091401": { "compartment": "compartment_17938", "id": "reaction_10091401", "reactome": "R-BTA-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091329" ], "products": [ "species_29372", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ], [ "species_10091399", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3B7L5", "ENSBTAT00000010532", "A0A3Q1MS15", "ENSBTAT00000083520", "A0A3Q1NF19", "ENSBTAT00000067422" ] }, "reaction_10091336": { "compartment": "compartment_17938", "id": "reaction_10091336", "reactome": "R-BTA-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29420", "species_10091329" ], "products": [ "species_29438", "species_10091333" ], "modifiers": [ [ "species_10091329", "catalyst" ] ], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "Q3SX43", "ENSBTAT00000031476", "species_29420", "Q0VD29", "ENSBTAT00000012331", "species_29438", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091354": { "compartment": "compartment_17938", "id": "reaction_10091354", "reactome": "R-BTA-9640168", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091344" ], "products": [ "species_10091342", "species_10091338" ], "modifiers": [], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530" ] }, "reaction_10091356": { "compartment": "compartment_17938", "id": "reaction_10091356", "reactome": "R-BTA-9640175", "name": "v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091333", "species_10091338" ], "products": [ "species_10091340" ], "modifiers": [], "additional_components": [ "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928" ] }, "reaction_10091404": { "compartment": "compartment_17938", "id": "reaction_10091404", "reactome": "R-BTA-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039057", "species_10091358" ], "products": [ "species_10091360" ], "modifiers": [], "additional_components": [ "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091365": { "compartment": "compartment_17938", "id": "reaction_10091365", "reactome": "R-BTA-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091360" ], "products": [ "species_29372", "species_10091362" ], "modifiers": [ [ "species_10091360", "catalyst" ] ], "additional_components": [ "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "A0A3Q1LSR3", "ENSBTAT00000073291", "species_29438", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "F1MG06", "ENSBTAT00000003739", "Q17QU5", "ENSBTAT00000053181", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LSR3", "ENSBTAT00000073291" ] }, "reaction_10091351": { "compartment": "compartment_17938", "id": "reaction_10091351", "reactome": "R-BTA-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10091340" ], "products": [ "species_29420", "species_10091344" ], "modifiers": [ [ "species_10091340", "catalyst" ], [ "species_10091349", "inhibitor" ] ], "additional_components": [ "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q3SX43", "ENSBTAT00000031476", "species_29438", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "A0A3Q1LYC8", "ENSBTAT00000084666", "species_113530", "Q3SX43", "ENSBTAT00000031476", "species_29420", "A0A3Q1MVT8", "ENSBTAT00000075507", "Q0VD29", "ENSBTAT00000012331", "Q28029", "ENSBTAT00000009961", "P79251", "ENSBTAT00000000240", "Q0VCV6", "ENSBTAT00000019267", "E1BMV6", "ENSBTAT00000026498", "P31408", "ENSBTAT00000024812", "A0A3Q1M3I3", "ENSBTAT00000073116", "A0A3Q1LPK7", "ENSBTAT00000075634", "A0A3Q1MSR2", "ENSBTAT00000075634", "Q32LB7", "ENSBTAT00000018250", "P21282", "ENSBTAT00000017968", "A4IFJ9", "ENSBTAT00000032875", "A0A3Q1NBC9", "ENSBTAT00000073497", "A0A452DJ67", "ENSBTAT00000073497", "Q1RMS1", "ENSBTAT00000000367", "P81103", "ENSBTAT00000020094", "A0A452DI38", "ENSBTAT00000007912", "Q3T132", "ENSBTAT00000048084", "Q17QQ1", "ENSBTAT00000047833", "Q2M2U3", "ENSBTAT00000019980", "Q3SZ68", "ENSBTAT00000019928", "ENSBTAT00000087052" ] }, "reaction_10073481": { "compartment": "compartment_70101", "id": "reaction_10073481", "reactome": "R-BTA-5662986", "name": "MT2A binds copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_3299744" ], "products": [ "species_10073479" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_3299744", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073464": { "compartment": "compartment_70101", "id": "reaction_10073464", "reactome": "R-BTA-5662613", "name": "MT3 exchanges zinc for copper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073444", "species_209799" ], "products": [ "species_10073462", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "P37359", "ENSBTAT00000022460", "species_29426", "species_3299744", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073468": { "compartment": "compartment_70101", "id": "reaction_10073468", "reactome": "R-BTA-5662620", "name": "MT3 binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_1132098" ], "products": [ "species_10073466" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_1132098", "P37359", "ENSBTAT00000022460" ] }, "reaction_10073460": { "compartment": "compartment_70101", "id": "reaction_10073460", "reactome": "R-BTA-5662608", "name": "MT2A binds cadmium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073456", "species_1132098" ], "products": [ "species_10073458" ], "modifiers": [], "additional_components": [ "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373", "species_1132098", "A0A3Q1M6Y6", "ENSBTAT00000069619", "P68301", "ENSBTAT00000034373" ] }, "reaction_10073446": { "compartment": "compartment_70101", "id": "reaction_10073446", "reactome": "R-BTA-5662606", "name": "MT3 binds zinc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073442", "species_29426" ], "products": [ "species_10073444" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022460", "species_29426", "P37359", "ENSBTAT00000022460" ] }, "reaction_10075304": { "compartment": "compartment_7660", "id": "reaction_10075304", "reactome": "R-BTA-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075297" ], "products": [ "species_10075301", "species_30555" ], "modifiers": [ [ "species_10075297", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075323": { "compartment": "compartment_7660", "id": "reaction_10075323", "reactome": "R-BTA-5687673", "name": "MRN recruits LIG3:XRCC1 to MMEJ sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036900", "species_10075316" ], "products": [ "species_10075321" ], "modifiers": [], "additional_components": [ "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075306": { "compartment": "compartment_7660", "id": "reaction_10075306", "reactome": "R-BTA-5687465", "name": "MRN complex binds RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068852", "species_10074778" ], "products": [ "species_10075297" ], "modifiers": [], "additional_components": [ "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10075326": { "compartment": "compartment_7660", "id": "reaction_10075326", "reactome": "R-BTA-5687675", "name": "LIG3 ligates remaining SSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075321" ], "products": [ "species_10035718", "species_10036900", "species_10074778", "species_5687670" ], "modifiers": [ [ "species_10075321", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817", "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "F1N2F9", "ENSBTAT00000081405", "A0A3Q1LF81", "ENSBTAT00000075817" ] }, "reaction_10075319": { "compartment": "compartment_7660", "id": "reaction_10075319", "reactome": "R-BTA-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10075312" ], "products": [ "species_10075316", "species_68454", "species_10036890" ], "modifiers": [ [ "species_10075312", "catalyst" ] ], "additional_components": [ "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000000071", "Q58DH8", "ENSBTAT00000000071", "A0A3Q1NLY2", "ENSBTAT00000085498", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10086350": { "compartment": "compartment_876", "id": "reaction_10086350", "reactome": "R-BTA-8932955", "name": "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189227", "species_74113" ], "products": [ "species_83910", "species_189254" ], "modifiers": [ [ "species_10086347", "catalyst" ], [ "species_10051281", "inhibitor" ] ], "additional_components": [ "species_188995", "species_70113", "species_70113", "species_188995", "ENSBTAT00000084455", "ENSBTAT00000055483" ] }, "reaction_10057350": { "compartment": "compartment_876", "id": "reaction_10057350", "reactome": "R-BTA-1296024", "name": "Activation of ATP sensitive Potassium channels in neuroendocrine cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057347", "catalyst" ], [ "species_113592", "inhibitor" ] ], "additional_components": [ "Q2KHY6", "ENSBTAT00000003307", "A2VDS4", "ENSBTAT00000021523", "E1BKR6", "ENSBTAT00000046676" ] }, "reaction_10057399": { "compartment": "compartment_876", "id": "reaction_10057399", "reactome": "R-BTA-1296045", "name": "Activation of Potassium transport channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057396", "catalyst" ] ], "additional_components": [ "A0A3Q1N684", "ENSBTAT00000081253" ] }, "reaction_10033473": { "compartment": "compartment_7660", "id": "reaction_10033473", "reactome": "R-BTA-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033469" ], "products": [ "species_10033471" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083861", "ENSBTAT00000083861" ] }, "reaction_10084497": { "compartment": "compartment_7660", "id": "reaction_10084497", "reactome": "R-BTA-8857692", "name": "RNA demethylases demethylate N6-methyladenosine RNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8857725", "species_113671", "species_111793" ], "products": [ "species_8857850", "species_29478", "species_159942", "species_159939" ], "modifiers": [ [ "species_10084494", "catalyst" ] ], "additional_components": [ "species_71067", "A0A3Q1N5P9", "ENSBTAT00000081168", "A0A452DJ48", "ENSBTAT00000034976" ] }, "reaction_10090466": { "compartment": "compartment_70101", "id": "reaction_10090466", "reactome": "R-BTA-9025152", "name": "ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025151" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "CHEBI:138674", "CHEBI:138673", "ENSBTAT00000015911" ] }, "reaction_10090468": { "compartment": "compartment_70101", "id": "reaction_10090468", "reactome": "R-BTA-9025957", "name": "ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025155", "species_29368" ], "products": [ "species_9025960" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090477": { "compartment": "compartment_70101", "id": "reaction_10090477", "reactome": "R-BTA-9026408", "name": "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026407" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090470": { "compartment": "compartment_70101", "id": "reaction_10090470", "reactome": "R-BTA-9026003", "name": "ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026047" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090472": { "compartment": "compartment_70101", "id": "reaction_10090472", "reactome": "R-BTA-9026006", "name": "ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9026293" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090474": { "compartment": "compartment_70101", "id": "reaction_10090474", "reactome": "R-BTA-9026007", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_9026307", "species_29364" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10052888": { "compartment": "compartment_876", "id": "reaction_10052888", "reactome": "R-BTA-917807", "name": "holoTF:TFRC dimer translocates from plasma membrane to endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052876" ], "products": [ "species_10052886" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052923": { "compartment": "compartment_74700", "id": "reaction_10052923", "reactome": "R-BTA-917936", "name": "MCOLN1 transports Fe2+ from endosome lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917810" ], "products": [ "species_71067" ], "modifiers": [ [ "species_10052920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065500" ] }, "reaction_10052907": { "compartment": "compartment_70101", "id": "reaction_10052907", "reactome": "R-BTA-917814", "name": "apoTF:TFRC dimer translocates from endosome membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052903" ], "products": [ "species_10052905" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052925": { "compartment": "compartment_984", "id": "reaction_10052925", "reactome": "R-BTA-917987", "name": "TFRC dimer binds 2xholoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052874", "species_10052872" ], "products": [ "species_10052876" ], "modifiers": [], "additional_components": [ "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10052909": { "compartment": "compartment_171907", "id": "reaction_10052909", "reactome": "R-BTA-917835", "name": "Fe3+ dissociates from holoTF:TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052886" ], "products": [ "species_10052903", "species_917966" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "species_917966", "G3X6N3", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564" ] }, "reaction_10052911": { "compartment": "compartment_947586", "id": "reaction_10052911", "reactome": "R-BTA-917839", "name": "apo-Transferrin dissociates from the receptor complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052905" ], "products": [ "species_10051000", "species_10052872" ], "modifiers": [], "additional_components": [ "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "ENSBTAT00000009564", "E1BIG6", "ENSBTAT00000046421" ] }, "reaction_10076099": { "compartment": "compartment_876", "id": "reaction_10076099", "reactome": "R-BTA-5691154", "name": "HFE binds TFRC dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076095", "species_10052872" ], "products": [ "species_10076097" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017371", "E1BIG6", "ENSBTAT00000046421", "E1BIG6", "ENSBTAT00000046421", "Q5EEZ1", "ENSBTAT00000017371" ] }, "reaction_10052901": { "compartment": "compartment_171907", "id": "reaction_10052901", "reactome": "R-BTA-917811", "name": "STEAP3-like proteins reduce Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917882", "species_917966" ], "products": [ "species_917810" ], "modifiers": [ [ "species_10052898", "catalyst" ] ], "additional_components": [ "A0A3Q1LPT9", "ENSBTAT00000077862" ] }, "reaction_10036076": { "compartment": "compartment_7660", "id": "reaction_10036076", "reactome": "R-BTA-77585", "name": "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036050", "species_10036072" ], "products": [ "species_10036074" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10036052": { "compartment": "compartment_7660", "id": "reaction_10036052", "reactome": "R-BTA-77584", "name": "Binding of SLBP to Replication-Dependent Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036048", "species_10036044" ], "products": [ "species_10036050" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074628", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1N0Z1", "ENSBTAT00000074628" ] }, "reaction_10085967": { "compartment": "compartment_70101", "id": "reaction_10085967", "reactome": "R-BTA-8876312", "name": "SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876310", "species_74113" ], "products": [ "species_83910", "species_8876304" ], "modifiers": [ [ "species_10085964", "catalyst" ] ], "additional_components": [ "species_113557", "species_373863", "CHEBI:32544", "species_113557", "species_373863", "species_197230", "ENSBTAT00000029140" ] }, "reaction_10048768": { "compartment": "compartment_876", "id": "reaction_10048768", "reactome": "R-BTA-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048765", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033777" ] }, "reaction_10048740": { "compartment": "compartment_876", "id": "reaction_10048740", "reactome": "R-BTA-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10048737", "catalyst" ] ], "additional_components": [ "E1BD54", "ENSBTAT00000045797", "E1B9J2", "ENSBTAT00000001818" ] }, "reaction_10052040": { "compartment": "compartment_70101", "id": "reaction_10052040", "reactome": "R-BTA-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_29432", "species_893599" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10064346": { "compartment": "compartment_984", "id": "reaction_10064346", "reactome": "R-BTA-2160492", "name": "IL4I1:FAD oxidises L-Phe to kPPV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_351993", "species_352327" ], "products": [ "species_2022135", "species_351629", "species_2160466" ], "modifiers": [ [ "species_10064343", "catalyst" ] ], "additional_components": [ "species_113596", "F1N191", "ENSBTAT00000007580" ] }, "reaction_10033935": { "compartment": "compartment_70101", "id": "reaction_10033935", "reactome": "R-BTA-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10033932", "catalyst" ] ], "additional_components": [ "Q3ZBD3", "ENSBTAT00000015750" ] }, "reaction_10076974": { "compartment": "compartment_70101", "id": "reaction_10076974", "reactome": "R-BTA-5696365", "name": "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696361", "species_29356" ], "products": [ "species_29502", "species_29448", "species_5359061" ], "modifiers": [ [ "species_10076971", "catalyst" ] ], "additional_components": [ "Q32LE5", "ENSBTAT00000077904" ] }, "reaction_10033944": { "compartment": "compartment_70101", "id": "reaction_10033944", "reactome": "R-BTA-71164", "name": "homogentisate + O2 => maleylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30337" ], "products": [ "species_31135" ], "modifiers": [ [ "species_10033941", "catalyst" ] ], "additional_components": [ "A0A3Q1LS65", "ENSBTAT00000087453", "species_71067" ] }, "reaction_10033962": { "compartment": "compartment_70101", "id": "reaction_10033962", "reactome": "R-BTA-71181", "name": "fumarylacetoacetate => fumarate + acetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_31175" ], "products": [ "species_29666", "species_29586" ], "modifiers": [ [ "species_10033959", "catalyst" ] ], "additional_components": [ "A0A3Q1MPJ4", "ENSBTAT00000072597" ] }, "reaction_10033953": { "compartment": "compartment_70101", "id": "reaction_10033953", "reactome": "R-BTA-71173", "name": "maleylacetoacetate => fumarylacetoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31135" ], "products": [ "species_31175" ], "modifiers": [ [ "species_10033950", "catalyst" ] ], "additional_components": [ "A0A3Q1MEZ2", "ENSBTAT00000075831", "species_29450" ] }, "reaction_10075181": { "compartment": "compartment_7660", "id": "reaction_10075181", "reactome": "R-BTA-5686587", "name": "ABL1 phosphorylates RAD52", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10035844" ], "products": [ "species_113582", "species_10075178" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "A2VE43", "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617", "ENSBTAT00000080797" ] }, "reaction_10035846": { "compartment": "compartment_7660", "id": "reaction_10035846", "reactome": "R-BTA-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035842" ], "products": [ "species_10035844" ], "modifiers": [], "additional_components": [ "ENSBTAT00000055617", "A2VE43", "ENSBTAT00000055617" ] }, "reaction_10040183": { "compartment": "compartment_7660", "id": "reaction_10040183", "reactome": "R-BTA-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040167", "species_10040179", "species_10040175", "species_10040171" ], "products": [ "species_10040181" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026619", "ENSBTAT00000022773", "ENSBTAT00000012322", "ENSBTAT00000061540", "E1BC42", "ENSBTAT00000061540", "Q08E12", "ENSBTAT00000012322", "A2VE40", "ENSBTAT00000022773", "A4IFH4", "ENSBTAT00000026619" ] }, "reaction_10033504": { "compartment": "compartment_7660", "id": "reaction_10033504", "reactome": "R-BTA-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10033501", "catalyst" ] ], "additional_components": [ "ENSBTAT00000031920" ] }, "reaction_10038904": { "compartment": "compartment_5460", "id": "reaction_10038904", "reactome": "R-BTA-163320", "name": "Association of mTERF with the termination sequence", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038900", "species_164569" ], "products": [ "species_10038902" ], "modifiers": [], "additional_components": [ "ENSBTAT00000063305", "G3N2I6", "ENSBTAT00000063305" ] }, "reaction_10040864": { "compartment": "compartment_12045", "id": "reaction_10040864", "reactome": "R-BTA-191072", "name": "Synthesis of Cx43", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10040862" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002398" ] }, "reaction_10055833": { "compartment": "compartment_70101", "id": "reaction_10055833", "reactome": "R-BTA-990489", "name": "Kinesin-13 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055577" ], "products": [ "species_10055579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023059", "F1N0Y3", "ENSBTAT00000023059" ] }, "reaction_10055515": { "compartment": "compartment_70101", "id": "reaction_10055515", "reactome": "R-BTA-983194", "name": "Kinesin-1 is a heterotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055511", "species_10055501" ], "products": [ "species_10055513" ], "modifiers": [], "additional_components": [ "A0A3Q1MWH8", "ENSBTAT00000071358", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358" ] }, "reaction_10055645": { "compartment": "compartment_70101", "id": "reaction_10055645", "reactome": "R-BTA-983259", "name": "Kinesins move along microtubules consuming ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10055643" ], "products": [ "species_29370", "species_10055643" ], "modifiers": [], "additional_components": [ "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055823": { "compartment": "compartment_70101", "id": "reaction_10055823", "reactome": "R-BTA-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055559" ], "products": [ "species_10055561" ], "modifiers": [], "additional_components": [ "ENSBTAT00000012347", "E1BF29", "ENSBTAT00000012347" ] }, "reaction_10055647": { "compartment": "compartment_70101", "id": "reaction_10055647", "reactome": "R-BTA-983266", "name": "Kinesins bind microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10055641" ], "products": [ "species_10055643" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "Q08DH4", "ENSBTAT00000025752", "A6H7H2", "ENSBTAT00000023001", "A0A3Q1MWH8", "ENSBTAT00000071358", "E1BF29", "ENSBTAT00000012347", "F1N0Y3", "ENSBTAT00000023059", "E1BKE3", "ENSBTAT00000035821", "E1BG49", "ENSBTAT00000011898", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "E1BC41", "ENSBTAT00000060943", "species_29438", "species_29420" ] }, "reaction_10055827": { "compartment": "compartment_70101", "id": "reaction_10055827", "reactome": "R-BTA-984671", "name": "Chromokinesins form dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055825" ], "products": [ "species_10055555" ], "modifiers": [], "additional_components": [ "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936", "F1MCP5", "ENSBTAT00000076641", "A0A3Q1MG61", "ENSBTAT00000076936" ] }, "reaction_10055829": { "compartment": "compartment_70101", "id": "reaction_10055829", "reactome": "R-BTA-984689", "name": "Kinesin-7 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055565" ], "products": [ "species_10055567" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011898", "E1BG49", "ENSBTAT00000011898" ] }, "reaction_10055831": { "compartment": "compartment_70101", "id": "reaction_10055831", "reactome": "R-BTA-984733", "name": "Kinesin-3 is a dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055533" ], "products": [ "species_10055535" ], "modifiers": [], "additional_components": [ "ENSBTAT00000035821", "E1BKE3", "ENSBTAT00000035821" ] }, "reaction_10090460": { "compartment": "compartment_70101", "id": "reaction_10090460", "reactome": "R-BTA-9024872", "name": "ALOX15 oxidises 17(S)-Hp-DHA to PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024012" ], "products": [ "species_9024883" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090386": { "compartment": "compartment_70101", "id": "reaction_10090386", "reactome": "R-BTA-9020262", "name": "ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024522" ], "products": [ "species_29364", "species_9024893" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090708": { "compartment": "compartment_12045", "id": "reaction_10090708", "reactome": "R-BTA-9037761", "name": "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024886", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_9037755" ], "modifiers": [ [ "species_10090705", "catalyst" ] ], "additional_components": [ "F1MM10", "ENSBTAT00000061300", "F1MHN9", "ENSBTAT00000000094" ] }, "reaction_10091753": { "compartment": "compartment_70101", "id": "reaction_10091753", "reactome": "R-BTA-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9648300", "species_10084440" ], "products": [ "species_10085164" ], "modifiers": [], "additional_components": [ "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10084824": { "compartment": "compartment_70101", "id": "reaction_10084824", "reactome": "R-BTA-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084753", "species_10075931" ], "products": [ "species_10084779" ], "modifiers": [], "additional_components": [ "A0A3Q1MWJ5", "ENSBTAT00000082605", "ENSBTAT00000028591", "A0A3Q1MWJ5", "ENSBTAT00000082605" ] }, "reaction_10085116": { "compartment": "compartment_876", "id": "reaction_10085116", "reactome": "R-BTA-8866269", "name": "ARRB bind GPCRs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047876", "species_10085112" ], "products": [ "species_10085114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050078", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "E1BDG5", "ENSBTAT00000026930", "F1MLJ8", "ENSBTAT00000061370", "A0A3Q1MSZ4", "ENSBTAT00000078307", "Q28044", "ENSBTAT00000002779", "CHEBI:28918", "species_209789", "P41985", "ENSBTAT00000019534", "P48044", "ENSBTAT00000065044", "A0A3Q1LXY0", "ENSBTAT00000076190", "G3X811", "ENSBTAT00000050078" ] }, "reaction_10085166": { "compartment": "compartment_876", "id": "reaction_10085166", "reactome": "R-BTA-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085160", "species_10084440" ], "products": [ "species_10085162" ], "modifiers": [ [ "species_10085164", "inhibitor" ] ], "additional_components": [ "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "E1BIG6", "ENSBTAT00000046421", "G3X6N3", "ENSBTAT00000009564", "species_917966", "E1BPM3", "ENSBTAT00000026608", "F6RJ01", "ENSBTAT00000027753", "E1BK36", "ENSBTAT00000019955", "F1MJK4", "ENSBTAT00000037742", "Q28072", "ENSBTAT00000008462", "Q32L97", "ENSBTAT00000071023", "A0A3S5ZPN6", "ENSBTAT00000014549", "A0A3Q1LVF9", "ENSBTAT00000074327", "Q08DS7", "ENSBTAT00000076585", "A0A3Q1MCG7", "ENSBTAT00000050604" ] }, "reaction_10085134": { "compartment": "compartment_70101", "id": "reaction_10085134", "reactome": "R-BTA-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085126", "species_10085130" ], "products": [ "species_10085132" ], "modifiers": [], "additional_components": [ "G5E628", "ENSBTAT00000029117", "ENSBTAT00000084618", "A0A3Q1MSK9", "ENSBTAT00000084618", "G5E628", "ENSBTAT00000029117" ] }, "reaction_10085264": { "compartment": "compartment_876", "id": "reaction_10085264", "reactome": "R-BTA-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085260", "species_10045533" ], "products": [ "species_10085262" ], "modifiers": [], "additional_components": [ "A0A3Q1NKA6", "ENSBTAT00000070874", "ENSBTAT00000033040", "Q3T0Y8", "ENSBTAT00000033040", "A0A3Q1NKA6", "ENSBTAT00000070874" ] }, "reaction_10084819": { "compartment": "compartment_70101", "id": "reaction_10084819", "reactome": "R-BTA-8863721", "name": "NEDD8-STON binds TOR1 hexamer and COP9 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084815", "species_10084779", "species_10084793" ], "products": [ "species_10084817" ], "modifiers": [], "additional_components": [ "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10084757": { "compartment": "compartment_876", "id": "reaction_10084757", "reactome": "R-BTA-8863463", "name": "STON2 binds SYT proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084743", "species_10084753" ], "products": [ "species_10084755" ], "modifiers": [], "additional_components": [ "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1LZP6", "ENSBTAT00000081053", "A0A3Q1LXE7", "ENSBTAT00000080553" ] }, "reaction_10084822": { "compartment": "compartment_70101", "id": "reaction_10084822", "reactome": "R-BTA-8863723", "name": "COP9 and TOR1 deneddylate STON2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084817" ], "products": [ "species_10084753", "species_10084815", "species_10075931", "species_10084793" ], "modifiers": [ [ "species_10084817", "catalyst" ] ], "additional_components": [ "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696", "ENSBTAT00000028591", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MQM0", "ENSBTAT00000080374", "A0A3Q1MWJ5", "ENSBTAT00000082605", "A0A3Q1ME43", "ENSBTAT00000071522", "G3X736", "ENSBTAT00000025677", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "Q3SZA0", "ENSBTAT00000009128", "F1MBP8", "ENSBTAT00000003609", "A4FV74", "ENSBTAT00000007696" ] }, "reaction_10089048": { "compartment": "compartment_70101", "id": "reaction_10089048", "reactome": "R-BTA-8981606", "name": "Myoglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089044", "species_29368" ], "products": [ "species_10089046" ], "modifiers": [], "additional_components": [ "species_71185", "P02192", "ENSBTAT00000084629", "species_113533", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10089058": { "compartment": "compartment_70101", "id": "reaction_10089058", "reactome": "R-BTA-8981610", "name": "Neuroglobin binds oxygen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_10089054" ], "products": [ "species_10089056" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533" ] }, "reaction_10089060": { "compartment": "compartment_70101", "id": "reaction_10089060", "reactome": "R-BTA-8981621", "name": "Neuroglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089056" ], "products": [ "species_29368", "species_10089054" ], "modifiers": [], "additional_components": [ "species_71185", "Q6WZ19", "ENSBTAT00000021661", "species_113533", "species_71185", "Q6WZ19", "ENSBTAT00000021661" ] }, "reaction_10089062": { "compartment": "compartment_70101", "id": "reaction_10089062", "reactome": "R-BTA-8981622", "name": "Myoglobin:oxygen dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089046" ], "products": [ "species_10089044", "species_29368" ], "modifiers": [], "additional_components": [ "species_113533", "species_71185", "P02192", "ENSBTAT00000084629", "species_71185", "P02192", "ENSBTAT00000084629" ] }, "reaction_10049869": { "compartment": "compartment_876", "id": "reaction_10049869", "reactome": "R-BTA-446277", "name": "RhCG mediates ammonium efflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049628": { "compartment": "compartment_876", "id": "reaction_10049628", "reactome": "R-BTA-444393", "name": "RhCG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049625", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080155" ] }, "reaction_10049871": { "compartment": "compartment_876", "id": "reaction_10049871", "reactome": "R-BTA-446278", "name": "RhBG mediates ammonium influx into kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_140912" ], "products": [ "species_351626", "species_31633" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049635": { "compartment": "compartment_876", "id": "reaction_10049635", "reactome": "R-BTA-444419", "name": "RhBG mediates ammonium effflux out of kidney collecting duct cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_31633" ], "products": [ "species_70106", "species_140912" ], "modifiers": [ [ "species_10049632", "catalyst" ] ], "additional_components": [ "ENSBTAT00000050191" ] }, "reaction_10049371": { "compartment": "compartment_876", "id": "reaction_10049371", "reactome": "R-BTA-435349", "name": "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_435347" ], "products": [ "species_70106", "species_71067" ], "modifiers": [ [ "species_10049368", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068742" ] }, "reaction_10049402": { "compartment": "compartment_876", "id": "reaction_10049402", "reactome": "R-BTA-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10049399", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072292" ] }, "reaction_10049378": { "compartment": "compartment_876", "id": "reaction_10049378", "reactome": "R-BTA-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10049375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014489" ] }, "reaction_10088912": { "compartment": "compartment_70101", "id": "reaction_10088912", "reactome": "R-BTA-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10088909", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005787" ] }, "reaction_10049358": { "compartment": "compartment_876", "id": "reaction_10049358", "reactome": "R-BTA-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_446589" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10049355", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:641", "CHEBI:6801", "CHEBI:16737", "CHEBI:8428", "CHEBI:42820", "CHEBI:16737", "CHEBI:641", "CHEBI:46020", "CHEBI:6801", "ENSBTAT00000074816" ] }, "reaction_10049060": { "compartment": "compartment_876", "id": "reaction_10049060", "reactome": "R-BTA-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_429130" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10049057", "catalyst" ] ], "additional_components": [ "ENSBTAT00000061504" ] }, "reaction_10049078": { "compartment": "compartment_876", "id": "reaction_10049078", "reactome": "R-BTA-429571", "name": "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429652", "species_74113" ], "products": [ "species_83910", "species_429648" ], "modifiers": [ [ "species_10049075", "catalyst" ] ], "additional_components": [ "CHEBI:27372", "species_426910", "species_426910", "CHEBI:27372", "ENSBTAT00000004510" ] }, "reaction_10049592": { "compartment": "compartment_876", "id": "reaction_10049592", "reactome": "R-BTA-444100", "name": "PROT mediates L-proline uptake", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_352033", "species_74113" ], "products": [ "species_83910", "species_113538", "species_352022" ], "modifiers": [ [ "species_10049589", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035184" ] }, "reaction_10049613": { "compartment": "compartment_876", "id": "reaction_10049613", "reactome": "R-BTA-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10049610", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_209914", "species_390899", "species_209789", "species_209789", "CHEBI:28918", "species_390899", "species_159362", "species_209914", "ENSBTAT00000045811" ] }, "reaction_10049599": { "compartment": "compartment_876", "id": "reaction_10049599", "reactome": "R-BTA-444120", "name": "SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_266029", "species_74113" ], "products": [ "species_83910", "species_352022", "species_29424" ], "modifiers": [ [ "species_10049596", "catalyst" ] ], "additional_components": [ "ENSBTAT00000087022" ] }, "reaction_10049319": { "compartment": "compartment_876", "id": "reaction_10049319", "reactome": "R-BTA-433089", "name": "SOAT can transport taurolithocholate-3-sulphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_433120", "species_74113" ], "products": [ "species_83910", "species_176483" ], "modifiers": [ [ "species_10049316", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066284" ] }, "reaction_10049606": { "compartment": "compartment_876", "id": "reaction_10049606", "reactome": "R-BTA-444126", "name": "HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10049603", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002712" ] }, "reaction_10049080": { "compartment": "compartment_876", "id": "reaction_10049080", "reactome": "R-BTA-429581", "name": "SLC5A6 transports vitamins from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429605", "species_74113" ], "products": [ "species_429627", "species_83910" ], "modifiers": [ [ "species_10042645", "catalyst" ] ], "additional_components": [ "CHEBI:16494", "species_199207", "species_196820", "species_199207", "species_196820", "CHEBI:16494", "Q32LE7", "ENSBTAT00000017091", "F1MN65", "ENSBTAT00000032961" ] }, "reaction_10051577": { "compartment": "compartment_20699", "id": "reaction_10051577", "reactome": "R-BTA-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051580": { "compartment": "compartment_20699", "id": "reaction_10051580", "reactome": "R-BTA-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10051574", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004376" ] }, "reaction_10051587": { "compartment": "compartment_20699", "id": "reaction_10051587", "reactome": "R-BTA-744230", "name": "SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_744239" ], "products": [ "species_113578", "species_744233" ], "modifiers": [ [ "species_10051584", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026562" ] }, "reaction_10039874": { "compartment": "compartment_12045", "id": "reaction_10039874", "reactome": "R-BTA-174368", "name": "SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158601", "species_162756" ], "products": [ "species_3499326", "species_174384" ], "modifiers": [ [ "species_10039871", "catalyst" ] ], "additional_components": [ "A2VE55", "ENSBTAT00000026562" ] }, "reaction_10051899": { "compartment": "compartment_876", "id": "reaction_10051899", "reactome": "R-BTA-879594", "name": "SLCO4C1 mediates the transport of digoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879521" ], "products": [ "species_879517" ], "modifiers": [ [ "species_10051896", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021761" ] }, "reaction_10051866": { "compartment": "compartment_876", "id": "reaction_10051866", "reactome": "R-BTA-879575", "name": "SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051863", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "E1BC23", "ENSBTAT00000026117", "E1BPV8", "ENSBTAT00000021795", "F1MM56", "ENSBTAT00000003345", "F1MYV0", "ENSBTAT00000030217" ] }, "reaction_10051843": { "compartment": "compartment_876", "id": "reaction_10051843", "reactome": "R-BTA-879528", "name": "SLCO2A1 transports PGT substrates from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879566" ], "products": [ "species_879614" ], "modifiers": [ [ "species_10051840", "catalyst" ] ], "additional_components": [ "species_879535", "CHEBI:15544", "species_416911", "species_391930", "species_416911", "CHEBI:15544", "species_879535", "species_391930", "ENSBTAT00000001747" ] }, "reaction_10091250": { "compartment": "compartment_876", "id": "reaction_10091250", "reactome": "R-BTA-9631987", "name": "SLCO1B1 transports T3,T4 from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879603" ], "products": [ "species_879628" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "species_352326", "species_352331", "species_352326", "species_352331", "ENSBTAT00000030217" ] }, "reaction_10051879": { "compartment": "compartment_876", "id": "reaction_10051879", "reactome": "R-BTA-879584", "name": "SLCO3A1 isoform 1 has abroad substrate specificity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051868" ], "products": [ "species_10051872" ], "modifiers": [ [ "species_10051876", "catalyst" ] ], "additional_components": [ "species_352326", "CHEBI:15544", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "CHEBI:15544", "species_352326", "species_391930", "A0A3Q1LXY0", "ENSBTAT00000076190", "ENSBTAT00000055950" ] }, "reaction_10070928": { "compartment": "compartment_984", "id": "reaction_10070928", "reactome": "R-BTA-5229283", "name": "LCNs bind lipids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070924", "species_5229279" ], "products": [ "species_10070926" ], "modifiers": [], "additional_components": [ "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576", "species_5229279", "A0A3Q1LZ62", "ENSBTAT00000084009", "E1B9Y3", "ENSBTAT00000032576" ] }, "reaction_10051892": { "compartment": "compartment_876", "id": "reaction_10051892", "reactome": "R-BTA-879585", "name": "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_879559" ], "products": [ "species_879544" ], "modifiers": [ [ "species_10051889", "catalyst" ] ], "additional_components": [ "CHEBI:16196", "CHEBI:16196", "Q0VCQ2", "ENSBTAT00000020526", "A6QQD5", "ENSBTAT00000044112" ] }, "reaction_10036297": { "compartment": "compartment_70101", "id": "reaction_10036297", "reactome": "R-BTA-109539", "name": "Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179740", "species_74113" ], "products": [ "species_179741", "species_83910" ], "modifiers": [ [ "species_10036294", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83909", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "ENSBTAT00000021720" ] }, "reaction_10051545": { "compartment": "compartment_70101", "id": "reaction_10051545", "reactome": "R-BTA-727740", "name": "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727774" ], "products": [ "species_727737" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "ENSBTAT00000010219" ] }, "reaction_10071001": { "compartment": "compartment_5460", "id": "reaction_10071001", "reactome": "R-BTA-5250210", "name": "ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070999" ], "products": [ "species_10070983" ], "modifiers": [], "additional_components": [ "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036283": { "compartment": "compartment_70101", "id": "reaction_10036283", "reactome": "R-BTA-109530", "name": "Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179738", "species_74113" ], "products": [ "species_179739", "species_83910" ], "modifiers": [ [ "species_10036280", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "CHEBI:17256", "CHEBI:17256", "species_83909", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000075356" ] }, "reaction_10051547": { "compartment": "compartment_70101", "id": "reaction_10051547", "reactome": "R-BTA-727768", "name": "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_727737" ], "products": [ "species_727774" ], "modifiers": [ [ "species_10051542", "catalyst" ] ], "additional_components": [ "species_159362", "CHEBI:28918", "species_83909", "species_209914", "species_209789", "species_209789", "species_83909", "species_209914", "species_159362", "CHEBI:28918", "ENSBTAT00000010219" ] }, "reaction_10071003": { "compartment": "compartment_70101", "id": "reaction_10071003", "reactome": "R-BTA-5250217", "name": "ARL2:GTP binds ARL2BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070997", "species_10070995" ], "products": [ "species_10070999" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006363", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q2TA37", "ENSBTAT00000002890", "species_29438", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10070991": { "compartment": "compartment_5460", "id": "reaction_10070991", "reactome": "R-BTA-5250209", "name": "ARL2:GTP:ARL2BP binds SLC25A4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070983", "species_10070987" ], "products": [ "species_10070989" ], "modifiers": [], "additional_components": [ "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363", "ENSBTAT00000017580", "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10073838": { "compartment": "compartment_70616", "id": "reaction_10073838", "reactome": "R-BTA-5672027", "name": "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10070989", "catalyst" ] ], "additional_components": [ "P02722", "ENSBTAT00000017580", "species_29438", "Q2TA37", "ENSBTAT00000002890", "Q32PC9", "ENSBTAT00000006363" ] }, "reaction_10036290": { "compartment": "compartment_70101", "id": "reaction_10036290", "reactome": "R-BTA-109538", "name": "Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179737", "species_74113" ], "products": [ "species_179743", "species_83910" ], "modifiers": [ [ "species_10036287", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_83909", "CHEBI:17562", "species_83909", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "CHEBI:17562", "ENSBTAT00000024328" ] }, "reaction_10036274": { "compartment": "compartment_70101", "id": "reaction_10036274", "reactome": "R-BTA-109527", "name": "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179747" ], "products": [ "species_179742" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "ENSBTAT00000015948" ] }, "reaction_10036276": { "compartment": "compartment_70101", "id": "reaction_10036276", "reactome": "R-BTA-109529", "name": "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179742" ], "products": [ "species_179747" ], "modifiers": [ [ "species_10036271", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:16040", "species_83956", "CHEBI:17596", "CHEBI:16750", "CHEBI:16704", "species_83928", "species_29692", "species_29554", "CHEBI:17562", "species_5635947", "species_29850", "CHEBI:17596", "CHEBI:16750", "species_83956", "CHEBI:16704", "species_83928", "species_29850", "species_83909", "species_29692", "species_29554", "species_5635947", "CHEBI:17562", "CHEBI:16040", "ENSBTAT00000015948" ] }, "reaction_10038660": { "compartment": "compartment_70616", "id": "reaction_10038660", "reactome": "R-BTA-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113581", "species_113592" ], "modifiers": [ [ "species_10038657", "catalyst" ] ], "additional_components": [ "P32007", "ENSBTAT00000063682" ] }, "reaction_10048747": { "compartment": "compartment_876", "id": "reaction_10048747", "reactome": "R-BTA-427605", "name": "SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109277", "species_74113" ], "products": [ "species_29372", "species_83910" ], "modifiers": [ [ "species_10048744", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010384" ] }, "reaction_10085896": { "compartment": "compartment_70101", "id": "reaction_10085896", "reactome": "R-BTA-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_70106" ], "products": [ "species_113529", "species_113552" ], "modifiers": [ [ "species_10085893", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001624" ] }, "reaction_10049083": { "compartment": "compartment_876", "id": "reaction_10049083", "reactome": "R-BTA-429591", "name": "SLC5A5 cotransports Na+ with I- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209818", "species_74113" ], "products": [ "species_209785", "species_83910" ], "modifiers": [ [ "species_10043975", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021031" ] }, "reaction_10060218": { "compartment": "compartment_70616", "id": "reaction_10060218", "reactome": "R-BTA-1614546", "name": "Sulfate is exported to the cytosol in exchange for dicarboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_198498", "species_1614584" ], "products": [ "species_113544", "species_174375" ], "modifiers": [ [ "species_10045047", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000538" ] }, "reaction_10048821": { "compartment": "compartment_201753", "id": "reaction_10048821", "reactome": "R-BTA-428052", "name": "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_428548" ], "products": [ "species_70106", "species_428614" ], "modifiers": [ [ "species_10048818", "catalyst" ] ], "additional_components": [ "A4FV52", "ENSBTAT00000009255", "A6QLI1", "ENSBTAT00000007935", "E1BA07", "ENSBTAT00000001445" ] }, "reaction_10049173": { "compartment": "compartment_876", "id": "reaction_10049173", "reactome": "R-BTA-429767", "name": "Passive I- efflux mediated by SMCT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10049167", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015315" ] }, "reaction_10048601": { "compartment": "compartment_876", "id": "reaction_10048601", "reactome": "R-BTA-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_74113" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10048598", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076302" ] }, "reaction_10048618": { "compartment": "compartment_876", "id": "reaction_10048618", "reactome": "R-BTA-426155", "name": "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804", "species_352022" ], "products": [ "species_74126", "species_188972" ], "modifiers": [ [ "species_10048615", "catalyst" ] ], "additional_components": [ "E1BCI8", "ENSBTAT00000024019", "A0A3S5ZPL9", "ENSBTAT00000018852", "A0A3Q1NIV4", "ENSBTAT00000082311" ] }, "reaction_10048594": { "compartment": "compartment_876", "id": "reaction_10048594", "reactome": "R-BTA-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_188972", "species_74113" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10048591", "catalyst" ] ], "additional_components": [ "ENSBTAT00000046583" ] }, "reaction_10048795": { "compartment": "compartment_876", "id": "reaction_10048795", "reactome": "R-BTA-427998", "name": "Proton-coupled di- and tri-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428037" ], "products": [ "species_428026", "species_70106" ], "modifiers": [ [ "species_10048792", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:47923", "CHEBI:47923", "CHEBI:90799", "ENSBTAT00000001891" ] }, "reaction_10048802": { "compartment": "compartment_17938", "id": "reaction_10048802", "reactome": "R-BTA-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428040", "species_427984" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10048799", "catalyst" ] ], "additional_components": [ "species_29612", "CHEBI:90799", "CHEBI:46761", "species_29612", "ENSBTAT00000030236" ] }, "reaction_10048965": { "compartment": "compartment_201753", "id": "reaction_10048965", "reactome": "R-BTA-428625", "name": "Vesicular inhibitory amino acid transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428592", "species_428548" ], "products": [ "species_428632", "species_70106" ], "modifiers": [ [ "species_10048962", "catalyst" ] ], "additional_components": [ "species_29424", "species_428571", "species_428571", "species_29424", "ENSBTAT00000063578" ] }, "reaction_10048804": { "compartment": "compartment_876", "id": "reaction_10048804", "reactome": "R-BTA-428015", "name": "SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_428027", "species_29804", "species_74113" ], "products": [ "species_74126", "species_427997", "species_70106", "species_83910" ], "modifiers": [ [ "species_10044069", "catalyst" ] ], "additional_components": [ "species_427963", "CHEBI:17364", "species_210382", "species_427963", "CHEBI:17364", "species_210382", "F1MJN4", "ENSBTAT00000025456", "A6H774", "ENSBTAT00000017953", "P46411", "ENSBTAT00000024287", "F1MUT8", "ENSBTAT00000016615", "A0A3Q1MR13", "ENSBTAT00000069455" ] }, "reaction_10048491": { "compartment": "compartment_876", "id": "reaction_10048491", "reactome": "R-BTA-425483", "name": "SLC4A5,7,9 cotransport Na+ with 3HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_83910" ], "products": [ "species_425425", "species_74113" ], "modifiers": [ [ "species_10048488", "catalyst" ] ], "additional_components": [ "E1BBH7", "ENSBTAT00000006425", "E1BIN2", "ENSBTAT00000029024" ] }, "reaction_10048478": { "compartment": "compartment_876", "id": "reaction_10048478", "reactome": "R-BTA-425482", "name": "SLC4A1,2,3 exchanges HCO3- for Cl-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972", "species_111627" ], "products": [ "species_425425", "species_352022" ], "modifiers": [ [ "species_10048475", "catalyst" ] ], "additional_components": [ "E1BKK3", "ENSBTAT00000019936", "A0A3Q1M051", "ENSBTAT00000071207" ] }, "reaction_10049053": { "compartment": "compartment_876", "id": "reaction_10049053", "reactome": "R-BTA-429094", "name": "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10049050", "catalyst" ] ], "additional_components": [ "ENSBTAT00000066412" ] }, "reaction_10089038": { "compartment": "compartment_70101", "id": "reaction_10089038", "reactome": "R-BTA-8981570", "name": "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089035", "catalyst" ] ], "additional_components": [ "Q27994", "ENSBTAT00000012109" ] }, "reaction_10089024": { "compartment": "compartment_70101", "id": "reaction_10089024", "reactome": "R-BTA-8981553", "name": "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089021", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889", "A0A3Q1MA30", "ENSBTAT00000042945" ] }, "reaction_10085907": { "compartment": "compartment_70101", "id": "reaction_10085907", "reactome": "R-BTA-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10085904", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010116" ] }, "reaction_10089029": { "compartment": "compartment_70101", "id": "reaction_10089029", "reactome": "R-BTA-8981564", "name": "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10089026", "catalyst" ] ], "additional_components": [ "A2VDL2", "ENSBTAT00000042889" ] }, "reaction_10049046": { "compartment": "compartment_876", "id": "reaction_10049046", "reactome": "R-BTA-429036", "name": "SLC2A9 transports Fru, Glc, urate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429078" ], "products": [ "species_429148" ], "modifiers": [ [ "species_10049043", "catalyst" ] ], "additional_components": [ "species_70113", "species_30034", "species_29532", "species_70113", "species_30034", "species_29532", "ENSBTAT00000079223" ] }, "reaction_10037913": { "compartment": "compartment_984", "id": "reaction_10037913", "reactome": "R-BTA-140777", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037910", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037899": { "compartment": "compartment_876", "id": "reaction_10037899", "reactome": "R-BTA-140761", "name": "sequestered tissue factor -> tissue factor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037897" ], "products": [ "species_10037864" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009341", "ENSBTAT00000009341" ] }, "reaction_10037915": { "compartment": "compartment_984", "id": "reaction_10037915", "reactome": "R-BTA-140783", "name": "tissue factor (TF) + factor VII (F7) -> TF:F7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903", "species_10037864" ], "products": [ "species_10037910" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "species_74016", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037887": { "compartment": "compartment_984", "id": "reaction_10037887", "reactome": "R-BTA-140736", "name": "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037857", "species_74112" ], "products": [ "species_10037859", "species_10037807" ], "modifiers": [ [ "species_10037884", "catalyst" ] ], "additional_components": [ "A0A452DIP8", "ENSBTAT00000021789", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10037937": { "compartment": "compartment_984", "id": "reaction_10037937", "reactome": "R-BTA-140825", "name": "TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037807", "species_10037884", "species_10037931" ], "products": [ "species_10037935" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016", "ENSBTAT00000085417", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "A0A3Q1NLA0", "ENSBTAT00000085417", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746" ] }, "reaction_10037906": { "compartment": "compartment_984", "id": "reaction_10037906", "reactome": "R-BTA-140769", "name": "factor VII -> factor VIIa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037903" ], "products": [ "species_10037893" ], "modifiers": [ [ "species_10037807", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "P22457", "ENSBTAT00000009746", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037895": { "compartment": "compartment_984", "id": "reaction_10037895", "reactome": "R-BTA-140748", "name": "tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037893", "species_10037864" ], "products": [ "species_10037884" ], "modifiers": [ [ "species_74112", "catalyst" ] ], "additional_components": [ "species_74016", "P22457", "ENSBTAT00000009746", "ENSBTAT00000009341", "P30931", "ENSBTAT00000009341", "P22457", "ENSBTAT00000009746", "species_74016" ] }, "reaction_10048635": { "compartment": "compartment_876", "id": "reaction_10048635", "reactome": "R-BTA-426223", "name": "Cation influx mediated by TRPC3/6/7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426219" ], "products": [ "species_426221" ], "modifiers": [ [ "species_10048630", "catalyst" ] ], "additional_components": [ "species_83910", "species_74016", "species_29926", "species_74016", "species_29926", "species_83910", "species_6797635", "A0A3Q1M4W2", "ENSBTAT00000077611", "A0A3Q1LTG6", "ENSBTAT00000070979" ] }, "reaction_10037607": { "compartment": "compartment_876", "id": "reaction_10037607", "reactome": "R-BTA-139855", "name": "P2X1-mediated entry of Ca++ from plasma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10037604", "catalyst" ] ], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10044680": { "compartment": "compartment_7660", "id": "reaction_10044680", "reactome": "R-BTA-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044676", "species_29428" ], "products": [ "species_10044678" ], "modifiers": [], "additional_components": [ "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096", "P10103", "ENSBTAT00000024094", "P40673", "ENSBTAT00000020096" ] }, "reaction_10044142": { "compartment": "compartment_13231", "id": "reaction_10044142", "reactome": "R-BTA-211206", "name": "Translocation of DFF to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044132" ], "products": [ "species_10044140" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044144": { "compartment": "compartment_7660", "id": "reaction_10044144", "reactome": "R-BTA-211207", "name": "Cleaved fragments of DFF45 dissociate from DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044108" ], "products": [ "species_10044098", "species_10044094", "species_10044106", "species_10044104" ], "modifiers": [], "additional_components": [ "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000026657", "ENSBTAT00000017999", "ENSBTAT00000017999" ] }, "reaction_10044146": { "compartment": "compartment_70101", "id": "reaction_10044146", "reactome": "R-BTA-211224", "name": "Association of DFF40 with DFF45", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044118", "species_10044120" ], "products": [ "species_10044122" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "ENSBTAT00000017999", "Q0VC37", "ENSBTAT00000017999", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10044116": { "compartment": "compartment_7660", "id": "reaction_10044116", "reactome": "R-BTA-211193", "name": "Homodimerization of DFF40", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044094" ], "products": [ "species_10044114" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026657", "F1N2E0", "ENSBTAT00000026657" ] }, "reaction_10066489": { "compartment": "compartment_70101", "id": "reaction_10066489", "reactome": "R-BTA-3000339", "name": "Phosphorylated BORA binds SCF-beta-TrCp1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10056243", "species_10066480" ], "products": [ "species_10066482" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "ENSBTAT00000026496", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10065938": { "compartment": "compartment_70101", "id": "reaction_10065938", "reactome": "R-BTA-2562594", "name": "Phosphorylated OPTN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065934" ], "products": [ "species_10065936" ], "modifiers": [], "additional_components": [ "ENSBTAT00000021808", "ENSBTAT00000021808" ] }, "reaction_10066487": { "compartment": "compartment_70101", "id": "reaction_10066487", "reactome": "R-BTA-3000335", "name": "SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066482", "species_10033408" ], "products": [ "species_10066484", "species_10056243" ], "modifiers": [ [ "species_10066482", "catalyst" ] ], "additional_components": [ "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "F1N3C9", "ENSBTAT00000026496", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449", "F1N3C9", "ENSBTAT00000026496", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1M118", "ENSBTAT00000075176", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10084216": { "compartment": "compartment_70101", "id": "reaction_10084216", "reactome": "R-BTA-8854052", "name": "Formation of the SCF-FBXL7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10039822", "species_10043871", "species_10039818" ], "products": [ "species_10084098" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004177", "ENSBTAT00000068449", "ENSBTAT00000075328", "ENSBTAT00000035306", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177" ] }, "reaction_10084206": { "compartment": "compartment_70101", "id": "reaction_10084206", "reactome": "R-BTA-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084100", "species_10033408" ], "products": [ "species_10084203" ], "modifiers": [ [ "species_10084100", "catalyst" ] ], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "Q2TA06", "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084102": { "compartment": "compartment_70101", "id": "reaction_10084102", "reactome": "R-BTA-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084086", "species_10084098" ], "products": [ "species_10084100" ], "modifiers": [], "additional_components": [ "ENSBTAT00000044590", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F1N019", "ENSBTAT00000004177", "Q2TA06", "ENSBTAT00000044590" ] }, "reaction_10084214": { "compartment": "compartment_70101", "id": "reaction_10084214", "reactome": "R-BTA-8854051", "name": "SCF-FBXL18 ubiquitinates FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10054914", "species_10033408" ], "products": [ "species_10084209" ], "modifiers": [ [ "species_10084211", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004177", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000004177", "Q3ZCF3", "ENSBTAT00000035306", "A0A3Q1LNF8", "ENSBTAT00000075328", "F1MYD0", "ENSBTAT00000068449", "F6PQR5", "ENSBTAT00000046646" ] }, "reaction_10039612": { "compartment": "compartment_13231", "id": "reaction_10039612", "reactome": "R-BTA-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039608" ], "products": [ "species_10039610" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10039614": { "compartment": "compartment_13231", "id": "reaction_10039614", "reactome": "R-BTA-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039610" ], "products": [ "species_10039608" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075264", "ENSBTAT00000075264" ] }, "reaction_10084043": { "compartment": "compartment_70101", "id": "reaction_10084043", "reactome": "R-BTA-8852331", "name": "GTSE1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084039" ], "products": [ "species_10084041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009339", "ENSBTAT00000009339" ] }, "reaction_10084028": { "compartment": "compartment_70101", "id": "reaction_10084028", "reactome": "R-BTA-8852280", "name": "GTSE1 binds microtubule lattice in interphase cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040838", "species_10084024" ], "products": [ "species_10084026" ], "modifiers": [], "additional_components": [ "species_29438", "species_29420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "species_29438", "species_29420" ] }, "reaction_10084047": { "compartment": "compartment_7660", "id": "reaction_10084047", "reactome": "R-BTA-8852337", "name": "GTSE1 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066675", "species_10084041" ], "products": [ "species_10084045" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000009339", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10084051": { "compartment": "compartment_70101", "id": "reaction_10084051", "reactome": "R-BTA-8852351", "name": "GTSE1 promotes translocation of TP53 to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084045" ], "products": [ "species_10084049" ], "modifiers": [], "additional_components": [ "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420", "F6Q0H8", "ENSBTAT00000009339", "P67939", "ENSBTAT00000001420" ] }, "reaction_10087635": { "compartment": "compartment_70616", "id": "reaction_10087635", "reactome": "R-BTA-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039037" ], "products": [ "species_10087633" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326" ] }, "reaction_10052963": { "compartment": "compartment_70101", "id": "reaction_10052963", "reactome": "R-BTA-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10052929", "species_10052959" ], "products": [ "species_10052961" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027868", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10083789": { "compartment": "compartment_876", "id": "reaction_10083789", "reactome": "R-BTA-8849891", "name": "SALMs 1-3 bind to PSD-95 family members", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083783", "species_10083785" ], "products": [ "species_10083787" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "A0A3Q1MFJ1", "ENSBTAT00000077778" ] }, "reaction_10083793": { "compartment": "compartment_876", "id": "reaction_10083793", "reactome": "R-BTA-8849900", "name": "SALMs1-3 bind each other in cis interactions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083785" ], "products": [ "species_10083791" ], "modifiers": [], "additional_components": [ "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062", "G3MZS2", "ENSBTAT00000063750", "E1BDP0", "ENSBTAT00000023907", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10084356": { "compartment": "compartment_876", "id": "reaction_10084356", "reactome": "R-BTA-8855648", "name": "SALM3 binds LAR-RPTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083779", "species_10046864" ], "products": [ "species_10084354" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053062", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "A0A3Q1M422", "ENSBTAT00000066459", "A0A3Q1MZF8", "ENSBTAT00000074444", "F1MJL8", "ENSBTAT00000053062" ] }, "reaction_10087862": { "compartment": "compartment_7660", "id": "reaction_10087862", "reactome": "R-BTA-8951676", "name": "RUNX3 binds TEADs and YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087858", "species_10084943" ], "products": [ "species_10087860" ], "modifiers": [], "additional_components": [ "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "F1MK73", "ENSBTAT00000006112", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10087997": { "compartment": "compartment_7660", "id": "reaction_10087997", "reactome": "R-BTA-8952058", "name": "CCND1 binds RUNX3 and displaces EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087908", "species_10056568" ], "products": [ "species_10053052", "species_10087995" ], "modifiers": [], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "ENSBTAT00000023277", "ENSBTAT00000021556", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087900": { "compartment": "compartment_7660", "id": "reaction_10087900", "reactome": "R-BTA-8951966", "name": "EP300 acetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10087887" ], "products": [ "species_2485002", "species_10087897" ], "modifiers": [ [ "species_10087887", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087889": { "compartment": "compartment_7660", "id": "reaction_10087889", "reactome": "R-BTA-8951951", "name": "RUNX3 binds EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084945", "species_10053052" ], "products": [ "species_10087887" ], "modifiers": [], "additional_components": [ "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10087910": { "compartment": "compartment_7660", "id": "reaction_10087910", "reactome": "R-BTA-8951977", "name": "Acetylated RUNX3 binds to BRD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087906", "species_10087897" ], "products": [ "species_10087908" ], "modifiers": [], "additional_components": [ "Q32S26", "ENSBTAT00000014704", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1B8D6", "ENSBTAT00000021556", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704" ] }, "reaction_10088006": { "compartment": "compartment_7660", "id": "reaction_10088006", "reactome": "R-BTA-8952069", "name": "HDAC4 deacetylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10088001" ], "products": [ "species_10087906", "species_10088003", "species_427486" ], "modifiers": [ [ "species_10088001", "catalyst" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "Q32S26", "ENSBTAT00000014704", "A0A452DIV3", "ENSBTAT00000023277", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567", "A0A452DIV3", "ENSBTAT00000023277", "Q32S26", "ENSBTAT00000014704", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088012": { "compartment": "compartment_7660", "id": "reaction_10088012", "reactome": "R-BTA-8952128", "name": "RUNX3 binds TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066677", "species_10084943" ], "products": [ "species_10088010" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "P67939", "ENSBTAT00000001420" ] }, "reaction_10086231": { "compartment": "compartment_7660", "id": "reaction_10086231", "reactome": "R-BTA-8878117", "name": "RUNX3 binds ZFHX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086227", "species_10084943" ], "products": [ "species_10086229" ], "modifiers": [], "additional_components": [ "ENSBTAT00000019489", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BPV9", "ENSBTAT00000019489" ] }, "reaction_10086587": { "compartment": "compartment_70101", "id": "reaction_10086587", "reactome": "R-BTA-8937807", "name": "SRC phosphorylates RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086579", "species_113592" ], "products": [ "species_29370", "species_10057248", "species_10086584" ], "modifiers": [ [ "species_10086579", "catalyst" ] ], "additional_components": [ "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767", "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10088490": { "compartment": "compartment_7660", "id": "reaction_10088490", "reactome": "R-BTA-8952419", "name": "SMURFs ubiquitinate RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10036828" ], "products": [ "species_10088485" ], "modifiers": [ [ "species_10088487", "catalyst" ], [ "species_10053052", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000070567", "ENSBTAT00000043725", "ENSBTAT00000021556" ] }, "reaction_10086589": { "compartment": "compartment_70101", "id": "reaction_10086589", "reactome": "R-BTA-8937814", "name": "RUNX3 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086577" ], "products": [ "species_10084943" ], "modifiers": [ [ "species_10057248", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567", "ENSBTAT00000011767" ] }, "reaction_10084947": { "compartment": "compartment_7660", "id": "reaction_10084947", "reactome": "R-BTA-8865454", "name": "CBFB binds RUNX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084943", "species_10084939" ], "products": [ "species_10084945" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000021434", "E1B9S8", "ENSBTAT00000021434", "A0A3Q1MYL2", "ENSBTAT00000070567" ] }, "reaction_10088482": { "compartment": "compartment_7660", "id": "reaction_10088482", "reactome": "R-BTA-8952399", "name": "Polyubiquitinated RUNX3 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088478" ], "products": [ "species_10088480" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070567", "ENSBTAT00000070567" ] }, "reaction_10086581": { "compartment": "compartment_70101", "id": "reaction_10086581", "reactome": "R-BTA-8937792", "name": "RUNX3 binds SRC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057248", "species_10086577" ], "products": [ "species_10086579" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000070567", "A0A3Q1MYL2", "ENSBTAT00000070567", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040059": { "compartment": "compartment_7660", "id": "reaction_10040059", "reactome": "R-BTA-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040054", "species_10040050" ], "products": [ "species_10040056" ], "modifiers": [ [ "species_10040054", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "F1MFW1", "ENSBTAT00000024392", "E1BG06", "ENSBTAT00000017599", "E1BB72", "ENSBTAT00000025568", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A6QNK6", "ENSBTAT00000002682", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525" ] }, "reaction_10040955": { "compartment": "compartment_70101", "id": "reaction_10040955", "reactome": "R-BTA-191636", "name": "Phosphorylation of Cx43 by c-src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10040945" ], "products": [ "species_29370", "species_10040952" ], "modifiers": [ [ "species_10040945", "catalyst" ] ], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "E1BIM8", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040961": { "compartment": "compartment_70101", "id": "reaction_10040961", "reactome": "R-BTA-191654", "name": "c-src associates with Cx43 in gap junctions", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040959", "species_10040957" ], "products": [ "species_10040945" ], "modifiers": [], "additional_components": [ "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "ENSBTAT00000011767", "F1N2D3", "ENSBTAT00000038824", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767" ] }, "reaction_10040967": { "compartment": "compartment_876", "id": "reaction_10040967", "reactome": "R-BTA-191656", "name": "Closure of gap junction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040965" ], "products": [ "species_10040965" ], "modifiers": [], "additional_components": [ "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398", "E1BIM8", "ENSBTAT00000011767", "P18246", "ENSBTAT00000002398" ] }, "reaction_10085313": { "compartment": "compartment_876", "id": "reaction_10085313", "reactome": "R-BTA-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10060424", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076329" ] }, "reaction_10083179": { "compartment": "compartment_263163", "id": "reaction_10083179", "reactome": "R-BTA-6814091", "name": "ARL1 recruits TGN Golgin homodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083175", "species_10083141" ], "products": [ "species_10083177" ], "modifiers": [], "additional_components": [ "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "E1BFF9", "ENSBTAT00000020327", "E1BJZ4", "ENSBTAT00000004036", "A0A3Q1MPM7", "ENSBTAT00000082501", "F1MUW6", "ENSBTAT00000046850" ] }, "reaction_10083149": { "compartment": "compartment_263163", "id": "reaction_10083149", "reactome": "R-BTA-6814088", "name": "SYS1 binds AcM-ARFRP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083119", "species_10083147" ], "products": [ "species_10083128" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438" ] }, "reaction_10083340": { "compartment": "compartment_432051", "id": "reaction_10083340", "reactome": "R-BTA-6814670", "name": "ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083331" ], "products": [ "species_10083335", "species_10083333", "species_10083337" ], "modifiers": [ [ "species_10083331", "catalyst" ] ], "additional_components": [ "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_29370", "Q5EA50", "ENSBTAT00000074576", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "ENSBTAT00000015669", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083342": { "compartment": "compartment_263163", "id": "reaction_10083342", "reactome": "R-BTA-6814675", "name": "RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083329", "species_10083323" ], "products": [ "species_10083331" ], "modifiers": [], "additional_components": [ "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "Q5EA50", "ENSBTAT00000074576", "Q3SX32", "ENSBTAT00000015669", "F1MIE6", "ENSBTAT00000037678", "P11456", "ENSBTAT00000067687", "Q08DW1", "ENSBTAT00000014511", "species_29438", "A0A3Q1M2K6", "ENSBTAT00000080085", "species_113592" ] }, "reaction_10083187": { "compartment": "compartment_70101", "id": "reaction_10083187", "reactome": "R-BTA-6814096", "name": "ARL1:GTP binds SCOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083183", "species_10083135" ], "products": [ "species_10083185" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065986", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q2YDM1", "ENSBTAT00000015767", "species_29438", "A0A3Q1M9K7", "ENSBTAT00000065986" ] }, "reaction_10083143": { "compartment": "compartment_263163", "id": "reaction_10083143", "reactome": "R-BTA-6814086", "name": "ARFRP1 recruits ARL1 to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083135", "species_10083128" ], "products": [ "species_10083141" ], "modifiers": [], "additional_components": [ "Q2YDM1", "ENSBTAT00000015767", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q1RMQ3", "ENSBTAT00000006825", "Q32LJ2", "ENSBTAT00000009858", "species_29438", "Q2YDM1", "ENSBTAT00000015767" ] }, "reaction_10083451": { "compartment": "compartment_20699", "id": "reaction_10083451", "reactome": "R-BTA-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083439" ], "products": [ "species_10083449" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083425": { "compartment": "compartment_20699", "id": "reaction_10083425", "reactome": "R-BTA-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060581", "species_10083421" ], "products": [ "species_10083423" ], "modifiers": [], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1MQ84", "ENSBTAT00000084706", "A0A3Q1MQ84", "ENSBTAT00000084706", "species_29438", "P84080", "ENSBTAT00000010159" ] }, "reaction_10083056": { "compartment": "compartment_20699", "id": "reaction_10083056", "reactome": "R-BTA-6811433", "name": "The COG tethering complex interacts with numerous SNAREs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083052" ], "products": [ "species_10083054" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "Q0II86", "ENSBTAT00000027666", "F1MDA6", "ENSBTAT00000027499", "E1BIQ3", "ENSBTAT00000005055", "Q08DB5", "ENSBTAT00000046561", "A0A3Q1NDZ1", "ENSBTAT00000083081", "A0A3Q1LTE3", "ENSBTAT00000075149", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10083458": { "compartment": "compartment_20699", "id": "reaction_10083458", "reactome": "R-BTA-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10083449" ], "products": [ "species_10083455" ], "modifiers": [ [ "species_10083449", "catalyst" ] ], "additional_components": [ "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "P84080", "ENSBTAT00000010159", "species_29420", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695", "species_29438", "P84080", "ENSBTAT00000010159", "A0A3Q1LM77", "ENSBTAT00000084376", "A0A3Q1M9S8", "ENSBTAT00000086938", "A0A3Q1LS50", "ENSBTAT00000086695" ] }, "reaction_10083767": { "compartment": "compartment_20699", "id": "reaction_10083767", "reactome": "R-BTA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082114", "species_10083763" ], "products": [ "species_10083765" ], "modifiers": [], "additional_components": [ "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BJ06", "ENSBTAT00000017437", "species_29438", "G3X7D3", "ENSBTAT00000024288", "A0A3Q1M591", "ENSBTAT00000073539", "E1BK29", "ENSBTAT00000007999", "F1MQ89", "ENSBTAT00000027073", "A0A452DKB6", "ENSBTAT00000045677", "E1BGA6", "ENSBTAT00000023803", "F1N5R4", "ENSBTAT00000002179", "Q3MHG0", "ENSBTAT00000017269" ] }, "reaction_10065827": { "compartment": "compartment_876", "id": "reaction_10065827", "reactome": "R-BTA-2534346", "name": "SPAM1 Binds Hyaluronic Acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065823", "species_1297302" ], "products": [ "species_10065825" ], "modifiers": [], "additional_components": [ "ENSBTAT00000045309", "species_1297302", "F1MZM9", "ENSBTAT00000045309" ] }, "reaction_10047292": { "compartment": "compartment_984", "id": "reaction_10047292", "reactome": "R-BTA-391155", "name": "SIRPA binds SFTPA oligomer, SFTPD oligomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10047270", "species_10047288" ], "products": [ "species_10047290" ], "modifiers": [], "additional_components": [ "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1NJ66", "ENSBTAT00000068360", "P35246", "ENSBTAT00000008579", "A0A3Q1M4J0", "ENSBTAT00000072837", "A0A3Q1NMT9", "ENSBTAT00000070673", "F1MRG6", "ENSBTAT00000012873", "F1MZ44", "ENSBTAT00000045380" ] }, "reaction_10060207": { "compartment": "compartment_70101", "id": "reaction_10060207", "reactome": "R-BTA-1614524", "name": "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_174369" ], "products": [ "species_1614518", "species_29356" ], "modifiers": [ [ "species_10060204", "catalyst" ] ], "additional_components": [ "species_71185", "F1MEW4", "ENSBTAT00000087445" ] }, "reaction_10060231": { "compartment": "compartment_70101", "id": "reaction_10060231", "reactome": "R-BTA-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_111707", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060275": { "compartment": "compartment_70101", "id": "reaction_10060275", "reactome": "R-BTA-1614654", "name": "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352015", "species_174369" ], "products": [ "species_174390", "species_1614585" ], "modifiers": [ [ "species_10060272", "catalyst" ] ], "additional_components": [ "species_29426", "A0A452DHV7", "ENSBTAT00000002916" ] }, "reaction_10057032": { "compartment": "compartment_70101", "id": "reaction_10057032", "reactome": "R-BTA-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_353106" ], "products": [ "species_1237165", "species_83951" ], "modifiers": [ [ "species_10057029", "catalyst" ] ], "additional_components": [ "Q3MHF7", "ENSBTAT00000048509" ] }, "reaction_10057023": { "compartment": "compartment_70101", "id": "reaction_10057023", "reactome": "R-BTA-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1237176" ], "products": [ "species_29372", "species_70106", "species_1237155" ], "modifiers": [ [ "species_10057020", "catalyst" ] ], "additional_components": [ "Q0VD27", "ENSBTAT00000019702", "species_29926" ] }, "reaction_10057684": { "compartment": "compartment_70101", "id": "reaction_10057684", "reactome": "R-BTA-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10057011", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003273" ] }, "reaction_10090681": { "compartment": "compartment_5460", "id": "reaction_10090681", "reactome": "R-BTA-9035484", "name": "CysS248-MPST:TXN2 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090677" ], "products": [ "species_10089847", "species_10067705", "species_1655881" ], "modifiers": [], "additional_components": [ "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014", "ENSBTAT00000069079", "ENSBTAT00000000014" ] }, "reaction_10089850": { "compartment": "compartment_5460", "id": "reaction_10089850", "reactome": "R-BTA-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090013": { "compartment": "compartment_5460", "id": "reaction_10090013", "reactome": "R-BTA-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012592", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10060252": { "compartment": "compartment_70101", "id": "reaction_10060252", "reactome": "R-BTA-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_111707" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10060255": { "compartment": "compartment_70101", "id": "reaction_10060255", "reactome": "R-BTA-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_174369" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10060225", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090015": { "compartment": "compartment_5460", "id": "reaction_10090015", "reactome": "R-BTA-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_9013191", "species_113557" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079" ] }, "reaction_10090679": { "compartment": "compartment_5460", "id": "reaction_10090679", "reactome": "R-BTA-9035227", "name": "TXN2 binds CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067702", "species_10090669" ], "products": [ "species_10090677" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000014", "ENSBTAT00000069079", "A0A3Q1M9D2", "ENSBTAT00000069079", "Q95108", "ENSBTAT00000000014" ] }, "reaction_10060361": { "compartment": "compartment_5460", "id": "reaction_10060361", "reactome": "R-BTA-1655879", "name": "Thiosulfate can transfer its sulfur atom to glutathione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_113529", "species_1655887" ], "products": [ "species_1655882", "species_1614538", "species_1655881" ], "modifiers": [ [ "species_10060358", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023735" ] }, "reaction_10060216": { "compartment": "compartment_5460", "id": "reaction_10060216", "reactome": "R-BTA-1614544", "name": "Sulfite is oxidized to sulfate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_1614538", "species_113521" ], "products": [ "species_1614617", "species_1614584" ], "modifiers": [ [ "species_10060213", "catalyst" ] ], "additional_components": [ "Q3MHX0", "ENSBTAT00000008101", "species_947539" ] }, "reaction_10060250": { "compartment": "compartment_70616", "id": "reaction_10060250", "reactome": "R-BTA-1614605", "name": "Persulfide sulfur is dioxygenated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_10060239", "species_113521" ], "products": [ "species_10060241", "species_113529", "species_1614538" ], "modifiers": [ [ "species_10060247", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013690", "ENSBTAT00000013690", "Q3T094", "ENSBTAT00000005747", "species_29426" ] }, "reaction_10060264": { "compartment": "compartment_70101", "id": "reaction_10060264", "reactome": "R-BTA-1614645", "name": "CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29368" ], "products": [ "species_1614519" ], "modifiers": [ [ "species_10060261", "catalyst" ] ], "additional_components": [ "A0A3Q1MCZ5", "ENSBTAT00000079843", "species_71067" ] }, "reaction_10060234": { "compartment": "compartment_70101", "id": "reaction_10060234", "reactome": "R-BTA-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614582", "species_1614532" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10090671": { "compartment": "compartment_5460", "id": "reaction_10090671", "reactome": "R-BTA-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089847", "species_9012592" ], "products": [ "species_113557", "species_10090669" ], "modifiers": [ [ "species_10089847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069079", "ENSBTAT00000069079", "ENSBTAT00000069079" ] }, "reaction_10083204": { "compartment": "compartment_70101", "id": "reaction_10083204", "reactome": "R-BTA-6814153", "name": "ADO oxidises 2AET to HTAU", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_6814151" ], "products": [ "species_1655445", "species_70106" ], "modifiers": [ [ "species_10083201", "catalyst" ] ], "additional_components": [ "G3MZK0", "ENSBTAT00000064438", "species_71067" ] }, "reaction_10060228": { "compartment": "compartment_70101", "id": "reaction_10060228", "reactome": "R-BTA-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10060225", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L1", "ENSBTAT00000005788" ] }, "reaction_10089959": { "compartment": "compartment_5460", "id": "reaction_10089959", "reactome": "R-BTA-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10089956", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043317" ] }, "reaction_10077124": { "compartment": "compartment_70101", "id": "reaction_10077124", "reactome": "R-BTA-5696838", "name": "BHMT2 tetramer transfers CH3 group from SMM to LHCYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4789070", "species_174369" ], "products": [ "species_70106", "species_174390" ], "modifiers": [ [ "species_10077121", "catalyst" ] ], "additional_components": [ "species_29426", "F1N4C6", "ENSBTAT00000048928" ] }, "reaction_10078575": { "compartment": "compartment_5460", "id": "reaction_10078575", "reactome": "R-BTA-6797913", "name": "SARDH:FAD oxidatively demethylates SARC to Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6797917", "species_113521" ], "products": [ "species_159549", "species_6797920" ], "modifiers": [ [ "species_10078572", "catalyst" ] ], "additional_components": [ "A0A3Q1MR10", "ENSBTAT00000075705", "species_113596" ] }, "reaction_10078582": { "compartment": "compartment_5460", "id": "reaction_10078582", "reactome": "R-BTA-6797961", "name": "CHDH oxidises Cho to BETALD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_6798162" ], "products": [ "species_6798194", "species_31649" ], "modifiers": [ [ "species_10078579", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013227" ] }, "reaction_10044844": { "compartment": "compartment_70101", "id": "reaction_10044844", "reactome": "R-BTA-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_204635", "species_353106" ], "modifiers": [ [ "species_10044841", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006978" ] }, "reaction_10044851": { "compartment": "compartment_70101", "id": "reaction_10044851", "reactome": "R-BTA-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10044848", "catalyst" ] ], "additional_components": [ "ENSBTAT00000054971" ] }, "reaction_10033778": { "compartment": "compartment_70101", "id": "reaction_10033778", "reactome": "R-BTA-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10033775", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005575" ] }, "reaction_10033788": { "compartment": "compartment_70101", "id": "reaction_10033788", "reactome": "R-BTA-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29406", "species_508182" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10033785", "catalyst" ] ], "additional_components": [ "CHEBI:57427", "CHEBI:58045", "species_29702", "CHEBI:28654", "CHEBI:17865", "CHEBI:16530", "A0A3Q1ML78", "ENSBTAT00000086973" ] }, "reaction_10033806": { "compartment": "compartment_5460", "id": "reaction_10033806", "reactome": "R-BTA-70785", "name": "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70772", "species_113521" ], "products": [ "species_70784" ], "modifiers": [ [ "species_10033803", "catalyst" ] ], "additional_components": [ "A0A3Q1M9N4", "ENSBTAT00000068139" ] }, "reaction_10051185": { "compartment": "compartment_5460", "id": "reaction_10051185", "reactome": "R-BTA-508369", "name": "alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_70836", "species_29362" ], "products": [ "species_70829", "species_113526" ], "modifiers": [ [ "species_10033812", "catalyst" ] ], "additional_components": [ "O02691", "ENSBTAT00000023642" ] }, "reaction_10033824": { "compartment": "compartment_5460", "id": "reaction_10033824", "reactome": "R-BTA-70844", "name": "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_70836" ], "products": [ "species_70843", "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10033797": { "compartment": "compartment_5460", "id": "reaction_10033797", "reactome": "R-BTA-70745", "name": "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_70715" ], "products": [ "species_70744", "species_31649" ], "modifiers": [ [ "species_10033794", "catalyst" ] ], "additional_components": [ "A0A452DI40", "ENSBTAT00000005782", "species_113596" ] }, "reaction_10052027": { "compartment": "compartment_70101", "id": "reaction_10052027", "reactome": "R-BTA-888614", "name": "IDO2 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10052024", "catalyst" ] ], "additional_components": [ "species_71185", "E1BPE1", "ENSBTAT00000007525" ] }, "reaction_10052043": { "compartment": "compartment_70101", "id": "reaction_10052043", "reactome": "R-BTA-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_29432", "species_893615" ], "modifiers": [ [ "species_10052037", "catalyst" ], [ "species_29502", "inhibitor" ], [ "species_8939576", "inhibitor" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10033979": { "compartment": "compartment_70101", "id": "reaction_10033979", "reactome": "R-BTA-71217", "name": "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34351", "species_29356" ], "products": [ "species_29432", "species_30487" ], "modifiers": [ [ "species_10033976", "catalyst" ] ], "additional_components": [ "A0A3Q1MB81", "ENSBTAT00000069075" ] }, "reaction_10052030": { "compartment": "compartment_5460", "id": "reaction_10052030", "reactome": "R-BTA-893583", "name": "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_893607" ], "products": [ "species_893617", "species_113552" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10033969": { "compartment": "compartment_70101", "id": "reaction_10033969", "reactome": "R-BTA-71200", "name": "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_29970" ], "products": [ "species_34351", "species_29356", "species_29366" ], "modifiers": [ [ "species_10033966", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073847" ] }, "reaction_10085381": { "compartment": "compartment_876", "id": "reaction_10085381", "reactome": "R-BTA-8870352", "name": "SLC36A4 transports L-Trp from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352006" ], "products": [ "species_29500" ], "modifiers": [ [ "species_10085378", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011246" ] }, "reaction_10033988": { "compartment": "compartment_70101", "id": "reaction_10033988", "reactome": "R-BTA-71218", "name": "3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_30487" ], "products": [ "species_36027" ], "modifiers": [ [ "species_10033985", "catalyst" ] ], "additional_components": [ "A0A452DIN3", "ENSBTAT00000006132", "species_71067" ] }, "reaction_10041894": { "compartment": "compartment_70101", "id": "reaction_10041894", "reactome": "R-BTA-198563", "name": "IDO1 dioxygenates L-Trp to NFK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29500", "species_29368" ], "products": [ "species_33179" ], "modifiers": [ [ "species_10041891", "catalyst" ] ], "additional_components": [ "species_71185", "A0A3Q1LFW8", "ENSBTAT00000070085" ] }, "reaction_10090155": { "compartment": "compartment_70101", "id": "reaction_10090155", "reactome": "R-BTA-9014627", "name": "SDS dimers:PXLP dehydrate L-Thr to 2AA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351990" ], "products": [ "species_29356", "species_9014643" ], "modifiers": [ [ "species_10090152", "catalyst" ] ], "additional_components": [ "A5PKH5", "ENSBTAT00000011776" ] }, "reaction_10090162": { "compartment": "compartment_70101", "id": "reaction_10090162", "reactome": "R-BTA-9014641", "name": "HRSP12 deaminates 2AA to 2OBUTA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9014643" ], "products": [ "species_29382", "species_936714" ], "modifiers": [ [ "species_10090159", "catalyst" ] ], "additional_components": [ "ENSBTAT00000016718" ] }, "reaction_10065455": { "compartment": "compartment_70101", "id": "reaction_10065455", "reactome": "R-BTA-2408524", "name": "Sec is reduced to H2Se by PXLP-K259-SCLY dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5359016", "species_5357697" ], "products": [ "species_5357660", "species_29432", "species_5359011" ], "modifiers": [ [ "species_10065452", "catalyst" ] ], "additional_components": [ "A2VDS1", "ENSBTAT00000013719" ] }, "reaction_10054601": { "compartment": "compartment_70101", "id": "reaction_10054601", "reactome": "R-BTA-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_29372", "species_200736" ], "modifiers": [ [ "species_10054598", "catalyst" ] ], "additional_components": [ "species_29926", "Q2KHU0", "ENSBTAT00000017392" ] }, "reaction_10054620": { "compartment": "compartment_70101", "id": "reaction_10054620", "reactome": "R-BTA-977348", "name": "PHGHD tetramer dehydrogenates 3PG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_29728" ], "products": [ "species_977329", "species_70106", "species_73473" ], "modifiers": [ [ "species_10054617", "catalyst" ] ], "additional_components": [ "A0A140T866", "ENSBTAT00000008907" ] }, "reaction_10090172": { "compartment": "compartment_70101", "id": "reaction_10090172", "reactome": "R-BTA-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10090175": { "compartment": "compartment_70101", "id": "reaction_10090175", "reactome": "R-BTA-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10090169", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10054611": { "compartment": "compartment_70101", "id": "reaction_10054611", "reactome": "R-BTA-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_977329", "species_29404" ], "products": [ "species_29406", "species_936706" ], "modifiers": [ [ "species_10054608", "catalyst" ] ], "additional_components": [ "A0A3S5ZPF7", "ENSBTAT00000018554" ] }, "reaction_10086371": { "compartment": "compartment_70101", "id": "reaction_10086371", "reactome": "R-BTA-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10086368", "catalyst" ] ], "additional_components": [ "A4FUZ5", "ENSBTAT00000002833", "A0A3Q1LF32", "ENSBTAT00000072137" ] }, "reaction_10090647": { "compartment": "compartment_70101", "id": "reaction_10090647", "reactome": "R-BTA-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29356", "species_29382", "species_29398" ], "modifiers": [ [ "species_10090169", "catalyst" ] ], "additional_components": [ "A0JNI4", "ENSBTAT00000005532" ] }, "reaction_10051165": { "compartment": "compartment_5460", "id": "reaction_10051165", "reactome": "R-BTA-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113593", "species_113600", "species_113552" ], "products": [ "species_113548", "species_113581", "species_31339", "species_113563" ], "modifiers": [ [ "species_10051162", "catalyst" ] ], "additional_components": [ "Q2KJH7", "ENSBTAT00000015703" ] }, "reaction_10077453": { "compartment": "compartment_70101", "id": "reaction_10077453", "reactome": "R-BTA-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_35305", "species_29364" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10077450", "catalyst" ] ], "additional_components": [ "Q58D08", "ENSBTAT00000022364" ] }, "reaction_10087455": { "compartment": "compartment_70101", "id": "reaction_10087455", "reactome": "R-BTA-8942575", "name": "N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_113592", "species_5691492" ], "products": [ "species_29370", "species_5693762" ], "modifiers": [ [ "species_10087452", "catalyst" ] ], "additional_components": [ "Q0VCE9", "ENSBTAT00000004262", "F1N0M1", "ENSBTAT00000023262" ] }, "reaction_10052046": { "compartment": "compartment_70101", "id": "reaction_10052046", "reactome": "R-BTA-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29472" ], "products": [ "species_29432", "species_893598" ], "modifiers": [ [ "species_10052037", "catalyst" ] ], "additional_components": [ "F6Q816", "ENSBTAT00000050582" ] }, "reaction_10077444": { "compartment": "compartment_5460", "id": "reaction_10077444", "reactome": "R-BTA-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_113590", "species_29362" ], "products": [ "species_113526", "species_379717" ], "modifiers": [ [ "species_10077441", "catalyst" ] ], "additional_components": [ "Q17QJ7", "ENSBTAT00000000047" ] }, "reaction_10077864": { "compartment": "compartment_5460", "id": "reaction_10077864", "reactome": "R-BTA-6788611", "name": "HYKK phosphorylates 5HLYS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788606", "species_113573" ], "products": [ "species_5696409", "species_113525" ], "modifiers": [ [ "species_10077861", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067508" ] }, "reaction_10077435": { "compartment": "compartment_17951", "id": "reaction_10077435", "reactome": "R-BTA-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_5693325" ], "products": [ "species_113575", "species_6783877" ], "modifiers": [ [ "species_10077432", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010444" ] }, "reaction_10045036": { "compartment": "compartment_5460", "id": "reaction_10045036", "reactome": "R-BTA-372480", "name": "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113577" ], "products": [ "species_29406", "species_70951" ], "modifiers": [ [ "species_10045033", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077809" ] }, "reaction_10051198": { "compartment": "compartment_5460", "id": "reaction_10051198", "reactome": "R-BTA-508561", "name": "alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70951", "species_113552" ], "products": [ "species_113594", "species_508531" ], "modifiers": [ [ "species_10033856", "catalyst" ] ], "additional_components": [ "A0A3Q1LKR3", "ENSBTAT00000085694" ] }, "reaction_10076261": { "compartment": "compartment_17951", "id": "reaction_10076261", "reactome": "R-BTA-5693347", "name": "CRYM reduces P2C to PPCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193465", "species_5693311", "species_113602" ], "products": [ "species_5693325", "species_389556" ], "modifiers": [ [ "species_10076258", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012972" ] }, "reaction_10033997": { "compartment": "compartment_17927", "id": "reaction_10033997", "reactome": "R-BTA-71275", "name": "arginine + glycine => ornithine + guanidoacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113530", "species_113545" ], "products": [ "species_113543", "species_113586" ], "modifiers": [ [ "species_10033994", "catalyst" ] ], "additional_components": [ "Q2HJ74", "ENSBTAT00000007338" ] }, "reaction_10042847": { "compartment": "compartment_70616", "id": "reaction_10042847", "reactome": "R-BTA-200326", "name": "creatine + ATP => phosphocreatine + ADP [CK octamer]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042844", "catalyst" ] ], "additional_components": [ "Q9TTK8", "ENSBTAT00000009871" ] }, "reaction_10034004": { "compartment": "compartment_70101", "id": "reaction_10034004", "reactome": "R-BTA-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_29916", "species_70106", "species_71285" ], "modifiers": [ [ "species_10034001", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005375" ] }, "reaction_10042838": { "compartment": "compartment_70101", "id": "reaction_10042838", "reactome": "R-BTA-200318", "name": "creatine + ATP => phosphocreatine + ADP [CKB,CKM]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29916", "species_113592" ], "products": [ "species_200351", "species_29370" ], "modifiers": [ [ "species_10042835", "catalyst" ] ], "additional_components": [ "Q5EA61", "ENSBTAT00000050490" ] }, "reaction_10066232": { "compartment": "compartment_70101", "id": "reaction_10066232", "reactome": "R-BTA-2752067", "name": "BESTs transport cytosolic HCO3- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627" ], "products": [ "species_425425" ], "modifiers": [ [ "species_10066224", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10084767": { "compartment": "compartment_876", "id": "reaction_10084767", "reactome": "R-BTA-8863494", "name": "ASICs bind STOML3, (STOM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065958", "species_10084763" ], "products": [ "species_10084765" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "F1MCB3", "ENSBTAT00000024268", "F1MCB3", "ENSBTAT00000024268", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10091583": { "compartment": "compartment_70101", "id": "reaction_10091583", "reactome": "R-BTA-9659568", "name": "ANO1 transports cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065970", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000067569" ] }, "reaction_10066206": { "compartment": "compartment_70101", "id": "reaction_10066206", "reactome": "R-BTA-2744242", "name": "TTYH2/3 transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066203", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080053" ] }, "reaction_10066270": { "compartment": "compartment_984", "id": "reaction_10066270", "reactome": "R-BTA-2872444", "name": "SLC9B1/C2 exchange Na+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_74113" ], "products": [ "species_351626", "species_83910" ], "modifiers": [ [ "species_10066267", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027774" ] }, "reaction_10066289": { "compartment": "compartment_17927", "id": "reaction_10066289", "reactome": "R-BTA-2889070", "name": "SLC9B2 exchanges Na+, Li+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_2889081" ], "products": [ "species_2889062", "species_163953" ], "modifiers": [ [ "species_10066286", "catalyst" ] ], "additional_components": [ "species_83910", "species_8953505", "species_8953505", "species_83910", "ENSBTAT00000085969" ] }, "reaction_10066227": { "compartment": "compartment_70101", "id": "reaction_10066227", "reactome": "R-BTA-2744361", "name": "BESTs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066224", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A1A4I7", "ENSBTAT00000046067" ] }, "reaction_10066034": { "compartment": "compartment_70101", "id": "reaction_10066034", "reactome": "R-BTA-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_74722", "species_352022" ], "modifiers": [ [ "species_10066031", "catalyst" ] ], "additional_components": [ "G3N3A9", "ENSBTAT00000064202", "E1BK15", "ENSBTAT00000027587" ] }, "reaction_10066004": { "compartment": "compartment_161320", "id": "reaction_10066004", "reactome": "R-BTA-2685505", "name": "TPCN1/2 transport lysosomal Ca2+ to cytosol ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606834" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10066001", "catalyst" ], [ "species_2730676", "catalyst" ] ], "additional_components": [ "A0A3Q1MQ38", "ENSBTAT00000082890", "A0A3Q1N2G9", "ENSBTAT00000077727" ] }, "reaction_10066199": { "compartment": "compartment_70101", "id": "reaction_10066199", "reactome": "R-BTA-2744228", "name": "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10066196", "catalyst" ] ], "additional_components": [ "E1BLQ0", "ENSBTAT00000012099", "E1BEP9", "ENSBTAT00000017615", "E1B792", "ENSBTAT00000049019" ] }, "reaction_10091542": { "compartment": "compartment_876", "id": "reaction_10091542", "reactome": "R-BTA-9650165", "name": "ASIC trimers bind H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_10091540" ], "products": [ "species_10065958" ], "modifiers": [], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "F1MGK7", "ENSBTAT00000061078", "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078" ] }, "reaction_10066282": { "compartment": "compartment_70101", "id": "reaction_10066282", "reactome": "R-BTA-2872498", "name": "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_83910" ], "products": [ "species_113551", "species_2892454" ], "modifiers": [ [ "species_10066279", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065965": { "compartment": "compartment_70101", "id": "reaction_10065965", "reactome": "R-BTA-2671885", "name": "ASIC trimers:H+ transport extracellular Na+ to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10065958", "catalyst" ], [ "species_2672379", "inhibitor" ], [ "species_2672383", "inhibitor" ], [ "species_10065963", "inhibitor" ] ], "additional_components": [ "F1MTH0", "ENSBTAT00000001283", "species_113529", "F1MGK7", "ENSBTAT00000061078", "ENSBTAT00000027364" ] }, "reaction_10066021": { "compartment": "compartment_70101", "id": "reaction_10066021", "reactome": "R-BTA-2730664", "name": "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113" ], "products": [ "species_83910" ], "modifiers": [ [ "species_10066018", "catalyst" ], [ "species_74016", "inhibitor" ] ], "additional_components": [ "A0A3Q1LL71", "ENSBTAT00000082451", "G3N0G4", "ENSBTAT00000065331", "F1MJ95", "ENSBTAT00000020495" ] }, "reaction_10066277": { "compartment": "compartment_70101", "id": "reaction_10066277", "reactome": "R-BTA-2872497", "name": "SLC17A3-2 transports cytosolic urate to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30034" ], "products": [ "species_429056" ], "modifiers": [ [ "species_10066274", "catalyst" ] ], "additional_components": [ "ENSBTAT00000035648" ] }, "reaction_10065991": { "compartment": "compartment_70101", "id": "reaction_10065991", "reactome": "R-BTA-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10065988", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "A0A3Q1M2M7", "ENSBTAT00000073921", "E1BJF8", "ENSBTAT00000022706", "A0A3Q1MCG6", "ENSBTAT00000067569", "A0A3Q1LNC2", "ENSBTAT00000071379", "A0A3Q1MUE0", "ENSBTAT00000078140" ] }, "reaction_10049035": { "compartment": "compartment_70101", "id": "reaction_10049035", "reactome": "R-BTA-428917", "name": "G13 activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049028" ], "products": [ "species_29420", "species_10049032" ], "modifiers": [ [ "species_10049028", "catalyst" ] ], "additional_components": [ "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "G5E6P3", "ENSBTAT00000062941", "species_29438", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_29420", "G5E6P3", "ENSBTAT00000062941", "P63212", "ENSBTAT00000003959" ] }, "reaction_10091701": { "compartment": "compartment_70101", "id": "reaction_10091701", "reactome": "R-BTA-9674529", "name": "AAMP binds to TBXA2R", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045856", "species_10091695" ], "products": [ "species_10091699" ], "modifiers": [ [ "species_391932", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000019892", "ENSBTAT00000005126", "Q3SZK1", "ENSBTAT00000005126", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10049014": { "compartment": "compartment_70101", "id": "reaction_10049014", "reactome": "R-BTA-428750", "name": "Gq activation by TP receptor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049009" ], "products": [ "species_29420", "species_10049011" ], "modifiers": [ [ "species_10049009", "catalyst" ] ], "additional_components": [ "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892", "species_391932", "Q95125", "ENSBTAT00000019892", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438", "P63212", "ENSBTAT00000003959", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29420", "P63212", "ENSBTAT00000003959", "species_391932", "Q95125", "ENSBTAT00000019892" ] }, "reaction_10048059": { "compartment": "compartment_70101", "id": "reaction_10048059", "reactome": "R-BTA-419003", "name": "Interaction of Nectins with Afadin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055", "species_10048049" ], "products": [ "species_10048057" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "ENSBTAT00000083796", "A0A3Q1LN46", "ENSBTAT00000083796", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048045": { "compartment": "compartment_204883", "id": "reaction_10048045", "reactome": "R-BTA-419001", "name": "Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_140648", "species_10048041" ], "products": [ "species_10048043" ], "modifiers": [], "additional_components": [ "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042", "E1BIA5", "ENSBTAT00000084008", "E1BQ10", "ENSBTAT00000015083", "A2VDQ6", "ENSBTAT00000081011", "F1MW29", "ENSBTAT00000020042", "A0A3Q1MB78", "ENSBTAT00000075672", "E1BF53", "ENSBTAT00000031089", "A0A5H1ZRH6", "ENSBTAT00000028238", "Q08DJ5", "ENSBTAT00000031090", "G3MZM2", "ENSBTAT00000065042" ] }, "reaction_10048348": { "compartment": "compartment_204883", "id": "reaction_10048348", "reactome": "R-BTA-420592", "name": "Transhomodimerization of Nectin-like (Necl) proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048344" ], "products": [ "species_10048346" ], "modifiers": [], "additional_components": [ "A0A3Q1M7P7", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841" ] }, "reaction_10048065": { "compartment": "compartment_204883", "id": "reaction_10048065", "reactome": "R-BTA-419011", "name": "Transhomodimerization of Nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048061" ], "products": [ "species_10048063" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048334": { "compartment": "compartment_204883", "id": "reaction_10048334", "reactome": "R-BTA-420584", "name": "Necl-1:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10048330" ], "products": [ "species_10048332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070841", "A0A3Q1M7P7", "ENSBTAT00000070841", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048352": { "compartment": "compartment_204883", "id": "reaction_10048352", "reactome": "R-BTA-420593", "name": "PVR:PVRL3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048053", "species_10042235" ], "products": [ "species_10048350" ], "modifiers": [], "additional_components": [ "ENSBTAT00000032332", "ENSBTAT00000070790", "A0A3Q1MRJ9", "ENSBTAT00000070790", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10048342": { "compartment": "compartment_204883", "id": "reaction_10048342", "reactome": "R-BTA-420591", "name": "Nectin-2:Nectin 3 trans heterodimer interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048338", "species_10048336" ], "products": [ "species_10048340" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396" ] }, "reaction_10049335": { "compartment": "compartment_876", "id": "reaction_10049335", "reactome": "R-BTA-433711", "name": "Cis-homodimerization of nectins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10048055" ], "products": [ "species_10048061" ], "modifiers": [], "additional_components": [ "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332", "A0A3Q1M4X8", "ENSBTAT00000083396", "F1MUF6", "ENSBTAT00000032332" ] }, "reaction_10044043": { "compartment": "compartment_70101", "id": "reaction_10044043", "reactome": "R-BTA-210294", "name": "Interaction of PECAM-1 and SHP-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040231", "species_10044014" ], "products": [ "species_10044041" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002653", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "F1N339", "ENSBTAT00000002653" ] }, "reaction_10049290": { "compartment": "compartment_70101", "id": "reaction_10049290", "reactome": "R-BTA-432148", "name": "Fgr may phosphorylate p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10049287", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "ENSBTAT00000078914" ] }, "reaction_10049283": { "compartment": "compartment_70101", "id": "reaction_10049283", "reactome": "R-BTA-432143", "name": "PECAM-1 binds PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041566", "species_10044014" ], "products": [ "species_10049281" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044018": { "compartment": "compartment_70101", "id": "reaction_10044018", "reactome": "R-BTA-210277", "name": "Interaction of PECAM-1 and SHP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043836" ], "products": [ "species_10044016" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000077529", "A0A3Q1M739", "ENSBTAT00000077529", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10049364": { "compartment": "compartment_876", "id": "reaction_10049364", "reactome": "R-BTA-435244", "name": "PECAM1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044026" ], "products": [ "species_29370", "species_10044014" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000086833" ] }, "reaction_10085323": { "compartment": "compartment_12045", "id": "reaction_10085323", "reactome": "R-BTA-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8869214" ], "products": [ "species_29416", "species_8869207" ], "modifiers": [ [ "species_10085320", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006727" ] }, "reaction_10048182": { "compartment": "compartment_984", "id": "reaction_10048182", "reactome": "R-BTA-419490", "name": "Binding of ATP to P2X receptors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037602", "species_114570" ], "products": [ "species_10037604" ], "modifiers": [], "additional_components": [ "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "Q5E9U1", "ENSBTAT00000014321", "F1MUF3", "ENSBTAT00000020298", "E1B742", "ENSBTAT00000025626", "species_113592" ] }, "reaction_10072426": { "compartment": "compartment_20699", "id": "reaction_10072426", "reactome": "R-BTA-5623513", "name": "ASAP1 stimulates GTPase activity of ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10072421" ], "products": [ "species_10072423", "species_29372", "species_10072399" ], "modifiers": [ [ "species_10072421", "catalyst" ] ], "additional_components": [ "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "P02699", "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LHY8", "ENSBTAT00000075339", "A0A3Q1M6P5", "ENSBTAT00000067242", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072401": { "compartment": "compartment_70101", "id": "reaction_10072401", "reactome": "R-BTA-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10072399" ], "products": [ "species_29420", "species_10072322" ], "modifiers": [ [ "species_10044823", "catalyst" ] ], "additional_components": [ "A0A3Q1LV05", "ENSBTAT00000074696", "species_29420", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "ENSBTAT00000061619" ] }, "reaction_10072326": { "compartment": "compartment_20699", "id": "reaction_10072326", "reactome": "R-BTA-5620914", "name": "ARF4:GTP binds VxPx-motifs of membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5623403", "species_10072322" ], "products": [ "species_10072324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001730", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "A0A3Q1LV05", "ENSBTAT00000074696", "species_29438", "P02699", "ENSBTAT00000001730" ] }, "reaction_10072475": { "compartment": "compartment_261122", "id": "reaction_10072475", "reactome": "R-BTA-5624127", "name": "ARL6:GTP and the BBSome target cargo to the primary cilium", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072451" ], "products": [ "species_10072467" ], "modifiers": [ [ "species_10072473", "inhibitor" ] ], "additional_components": [ "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072435": { "compartment": "compartment_70101", "id": "reaction_10072435", "reactome": "R-BTA-5624125", "name": "Formation of the BBSome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072245", "species_10072229", "species_10072257", "species_10072241", "species_10072253", "species_10072237", "species_10072249", "species_10072233" ], "products": [ "species_10072259" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006505", "ENSBTAT00000026844", "ENSBTAT00000064380", "ENSBTAT00000014216", "ENSBTAT00000042964", "ENSBTAT00000010013", "ENSBTAT00000008587", "ENSBTAT00000032389", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10072453": { "compartment": "compartment_876", "id": "reaction_10072453", "reactome": "R-BTA-5624126", "name": "ARL6:GTP and the BBSome bind ciliary cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072259", "species_10072449", "species_10072441" ], "products": [ "species_10072451" ], "modifiers": [], "additional_components": [ "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505", "G3MWT4", "ENSBTAT00000011728", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "Q0IIM2", "ENSBTAT00000013306", "species_29438", "G3MWT4", "ENSBTAT00000011728", "F1MU26", "ENSBTAT00000032389", "E1BHJ5", "ENSBTAT00000008587", "Q1JQ97", "ENSBTAT00000010013", "F1N4X0", "ENSBTAT00000042964", "A6QLF9", "ENSBTAT00000014216", "G3N2W1", "ENSBTAT00000064380", "E1BN34", "ENSBTAT00000026844", "F1MB52", "ENSBTAT00000006505" ] }, "reaction_10057569": { "compartment": "compartment_876", "id": "reaction_10057569", "reactome": "R-BTA-1296127", "name": "Activation of voltage gated Potassium channels", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057566", "catalyst" ] ], "additional_components": [ "Q4PJK1", "ENSBTAT00000024576", "A2VDT0", "ENSBTAT00000019888", "E1B7K3", "ENSBTAT00000064709", "F1MLD6", "ENSBTAT00000022142", "F1MTJ1", "ENSBTAT00000009938", "F1N0E8", "ENSBTAT00000010960", "G3N1T8", "ENSBTAT00000065475", "F1MKB0", "ENSBTAT00000020543", "E1B9N0", "ENSBTAT00000021458", "A0A3Q1MT75", "ENSBTAT00000087044", "A0A3Q1MFH2", "ENSBTAT00000086274", "A0A3Q1MPE6", "ENSBTAT00000074581", "E1BDC5", "ENSBTAT00000039169", "F1ML52", "ENSBTAT00000022193", "F1MJA9", "ENSBTAT00000018162", "E1BCM0", "ENSBTAT00000004406", "F1MC54", "ENSBTAT00000046307", "F1MP51", "ENSBTAT00000015122", "F1MY95", "ENSBTAT00000044879", "Q52PG9", "ENSBTAT00000011882", "F1MVI5", "ENSBTAT00000045500", "F1MPV7", "ENSBTAT00000010214", "E1BKI8", "ENSBTAT00000011681", "F1N553", "ENSBTAT00000007132", "A0A3Q1M6H7", "ENSBTAT00000071160", "A4FV89", "ENSBTAT00000028357", "F1MXZ4", "ENSBTAT00000011219", "E1BII8", "ENSBTAT00000023770", "E1B760", "ENSBTAT00000025668", "E1BLH0", "ENSBTAT00000005335", "F1MDM5", "ENSBTAT00000017003", "A0A3Q1LSF6", "ENSBTAT00000067149", "E1BMA2", "ENSBTAT00000022102" ] }, "reaction_10057365": { "compartment": "compartment_876", "id": "reaction_10057365", "reactome": "R-BTA-1296039", "name": "Activation of Ca2+ activated Potassium channels with small conductance", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057362", "catalyst" ] ], "additional_components": [ "E1BGY2", "ENSBTAT00000011376", "F1N467", "ENSBTAT00000014706" ] }, "reaction_10057665": { "compartment": "compartment_876", "id": "reaction_10057665", "reactome": "R-BTA-1299338", "name": "Activation of TRESK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057662", "catalyst" ] ], "additional_components": [ "F1MW24", "ENSBTAT00000020046" ] }, "reaction_10057656": { "compartment": "compartment_876", "id": "reaction_10057656", "reactome": "R-BTA-1299318", "name": "Activation of TASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057653", "catalyst" ] ], "additional_components": [ "A0A3Q1MT89", "ENSBTAT00000075452", "G3N1D1", "ENSBTAT00000063834" ] }, "reaction_10057682": { "compartment": "compartment_876", "id": "reaction_10057682", "reactome": "R-BTA-1299359", "name": "Activation of TALK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057679", "catalyst" ] ], "additional_components": [ "Q8HZT2", "ENSBTAT00000013646", "E1BEH1", "ENSBTAT00000030656" ] }, "reaction_10057616": { "compartment": "compartment_876", "id": "reaction_10057616", "reactome": "R-BTA-1299297", "name": "Activation of THIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10057613", "catalyst" ] ], "additional_components": [ "G3N1Q6", "ENSBTAT00000065420" ] }, "reaction_10090498": { "compartment": "compartment_70101", "id": "reaction_10090498", "reactome": "R-BTA-9027043", "name": "CYPs hydroxylate DHA to 14(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_9024011" ], "products": [ "species_29356", "species_29366", "species_9027049" ], "modifiers": [ [ "species_10090495", "catalyst" ] ], "additional_components": [ "A0A3S5ZP79", "ENSBTAT00000027159", "Q2KJJ2", "ENSBTAT00000000869", "F1MEU8", "ENSBTAT00000008918", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10084300": { "compartment": "compartment_876", "id": "reaction_10084300", "reactome": "R-BTA-8854628", "name": "MYLIP dimer ubiquitinates VLDLR on Lys-839", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084266" ], "products": [ "species_10084295" ], "modifiers": [ [ "species_10084297", "catalyst" ], [ "species_10045642", "catalyst" ] ], "additional_components": [ "ENSBTAT00000071362", "ENSBTAT00000071362", "A6QQD1", "ENSBTAT00000005377", "ENSBTAT00000071739" ] }, "reaction_10083113": { "compartment": "compartment_70101", "id": "reaction_10083113", "reactome": "R-BTA-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10083110", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026745" ] }, "reaction_10085994": { "compartment": "compartment_161320", "id": "reaction_10085994", "reactome": "R-BTA-8876472", "name": "NPC2 binds CHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085990", "species_8848047" ], "products": [ "species_10085992" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029271", "species_193840", "P79345", "ENSBTAT00000029271" ] }, "reaction_10086026": { "compartment": "compartment_12045", "id": "reaction_10086026", "reactome": "R-BTA-8876696", "name": "SOAT1,2 transfer acyl group to CHOL forming CHEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384", "species_1500578" ], "products": [ "species_8876704", "species_76194" ], "modifiers": [ [ "species_10086023", "catalyst" ] ], "additional_components": [ "ENSBTAT00000033962" ] }, "reaction_10086557": { "compartment": "compartment_70101", "id": "reaction_10086557", "reactome": "R-BTA-8937442", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_163579" ], "products": [ "species_8876730", "species_216762" ], "modifiers": [ [ "species_10086554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000056670" ] }, "reaction_10086002": { "compartment": "compartment_161320", "id": "reaction_10086002", "reactome": "R-BTA-8876484", "name": "NPC2 transfers CHOL to NPC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085998", "species_10085992" ], "products": [ "species_10085990", "species_10086000" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085568", "species_193840", "P79345", "ENSBTAT00000029271", "ENSBTAT00000029271", "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840" ] }, "reaction_10086004": { "compartment": "compartment_12045", "id": "reaction_10086004", "reactome": "R-BTA-8876485", "name": "CHOL translocates from lysosome membrane to ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086000" ], "products": [ "species_193384", "species_10085998" ], "modifiers": [], "additional_components": [ "A0A3Q1LT67", "ENSBTAT00000085568", "species_193840", "ENSBTAT00000085568" ] }, "reaction_10044020": { "compartment": "compartment_876", "id": "reaction_10044020", "reactome": "R-BTA-210282", "name": "Interaction of GPVI and FceRI gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037447", "species_10037453" ], "products": [ "species_10037455" ], "modifiers": [], "additional_components": [ "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426" ] }, "reaction_10049300": { "compartment": "compartment_70101", "id": "reaction_10049300", "reactome": "R-BTA-432295", "name": "GPVI binds Fyn and Lyn", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037463", "species_10037459", "species_10037455" ], "products": [ "species_10037465" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075171", "ENSBTAT00000015730", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10040521": { "compartment": "compartment_7660", "id": "reaction_10040521", "reactome": "R-BTA-187545", "name": "Association of Cks1 with SCF(Skp2) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040517", "species_10040513" ], "products": [ "species_10040519" ], "modifiers": [], "additional_components": [ "ENSBTAT00000033975", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040542": { "compartment": "compartment_7660", "id": "reaction_10040542", "reactome": "R-BTA-187575", "name": "Ubiquitination of phospho-p27/p21", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10040537" ], "products": [ "species_10040539" ], "modifiers": [ [ "species_10040537", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10040576": { "compartment": "compartment_13231", "id": "reaction_10040576", "reactome": "R-BTA-187828", "name": "Translocation of p21 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040572" ], "products": [ "species_10040574" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011001", "ENSBTAT00000011001" ] }, "reaction_10040503": { "compartment": "compartment_13231", "id": "reaction_10040503", "reactome": "R-BTA-187506", "name": "Translocation of p27 to the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040499" ], "products": [ "species_10040501" ], "modifiers": [], "additional_components": [ "ENSBTAT00000024297", "ENSBTAT00000024297" ] }, "reaction_10033512": { "compartment": "compartment_7660", "id": "reaction_10033512", "reactome": "R-BTA-69299", "name": "Cdt1 associates with geminin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033414", "species_10033508" ], "products": [ "species_10033510" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067336", "ENSBTAT00000023040", "Q56JZ0", "ENSBTAT00000023040", "A0A3Q1LIW5", "ENSBTAT00000067336" ] }, "reaction_10033466": { "compartment": "compartment_7660", "id": "reaction_10033466", "reactome": "R-BTA-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033462", "species_68419" ], "products": [ "species_10033464" ], "modifiers": [], "additional_components": [ "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798", "E1BIF0", "ENSBTAT00000009882", "Q3SZN5", "ENSBTAT00000000316", "A6QQ14", "ENSBTAT00000047798" ] }, "reaction_10087385": { "compartment": "compartment_70101", "id": "reaction_10087385", "reactome": "R-BTA-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087381", "species_10040351" ], "products": [ "species_10087383" ], "modifiers": [ [ "species_10040353", "inhibitor" ] ], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A3Q1LYR9", "ENSBTAT00000083400", "A7MBB9", "ENSBTAT00000014685", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675" ] }, "reaction_10056616": { "compartment": "compartment_7660", "id": "reaction_10056616", "reactome": "R-BTA-1226095", "name": "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056608" ], "products": [ "species_10056566", "species_113582", "species_10056614" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "E1BMR3", "ENSBTAT00000015333", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000015333", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057816": { "compartment": "compartment_7660", "id": "reaction_10057816", "reactome": "R-BTA-1363328", "name": "Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040519", "species_10056564" ], "products": [ "species_10057814" ], "modifiers": [], "additional_components": [ "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10056602": { "compartment": "compartment_7660", "id": "reaction_10056602", "reactome": "R-BTA-1226094", "name": "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10056559" ], "products": [ "species_113582", "species_10056566", "species_10056564" ], "modifiers": [ [ "species_10056599", "catalyst" ] ], "additional_components": [ "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "A0A3Q1M1Y7", "ENSBTAT00000084739", "F1MBE6", "ENSBTAT00000015999", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q17QZ4", "ENSBTAT00000084839", "F1MBE6", "ENSBTAT00000015999", "ENSBTAT00000084739", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10057821": { "compartment": "compartment_7660", "id": "reaction_10057821", "reactome": "R-BTA-1363331", "name": "Ubiquitination of p130 (RBL2) by SCF (Skp2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057814", "species_10036828" ], "products": [ "species_10040519", "species_10057818" ], "modifiers": [ [ "species_10057814", "catalyst" ] ], "additional_components": [ "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1M1Y7", "ENSBTAT00000084739", "A0A3Q1M1Y7", "ENSBTAT00000084739", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449", "A7MB09", "ENSBTAT00000018036", "Q0P5A5", "ENSBTAT00000033975" ] }, "reaction_10087487": { "compartment": "compartment_70101", "id": "reaction_10087487", "reactome": "R-BTA-8942607", "name": "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10087392" ], "products": [ "species_29370", "species_10087465" ], "modifiers": [ [ "species_10087484", "catalyst" ] ], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001" ] }, "reaction_10087503": { "compartment": "compartment_13231", "id": "reaction_10087503", "reactome": "R-BTA-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087491" ], "products": [ "species_10087501" ], "modifiers": [], "additional_components": [ "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297" ] }, "reaction_10087394": { "compartment": "compartment_70101", "id": "reaction_10087394", "reactome": "R-BTA-8941915", "name": "Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10087383", "species_10087390" ], "products": [ "species_10087392" ], "modifiers": [], "additional_components": [ "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "A5PKM2", "ENSBTAT00000011001", "A6QLS3", "ENSBTAT00000024297", "Q32KY4", "ENSBTAT00000079975", "E1BC36", "ENSBTAT00000068675", "A0A452DIV3", "ENSBTAT00000023277" ] }, "reaction_10065794": { "compartment": "compartment_70101", "id": "reaction_10065794", "reactome": "R-BTA-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065782", "species_29356" ], "products": [ "species_29372", "species_10065792" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562", "F1N3G4", "ENSBTAT00000019603", "F1MH70", "ENSBTAT00000017174", "E1BMZ9", "ENSBTAT00000007705", "F1MY41", "ENSBTAT00000011562" ] }, "reaction_10035745": { "compartment": "compartment_13231", "id": "reaction_10035745", "reactome": "R-BTA-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035737" ], "products": [ "species_10035743" ], "modifiers": [], "additional_components": [ "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975", "A0A452DIV3", "ENSBTAT00000023277", "Q32KY4", "ENSBTAT00000079975" ] }, "reaction_10035747": { "compartment": "compartment_13231", "id": "reaction_10035747", "reactome": "R-BTA-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035731" ], "products": [ "species_10035739" ], "modifiers": [], "additional_components": [ "ENSBTAT00000023277", "ENSBTAT00000023277" ] }, "reaction_10074692": { "compartment": "compartment_7660", "id": "reaction_10074692", "reactome": "R-BTA-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074688" ], "products": [ "species_10074690" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10074695": { "compartment": "compartment_7660", "id": "reaction_10074695", "reactome": "R-BTA-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074690" ], "products": [ "species_113582", "species_10033532" ], "modifiers": [ [ "species_10074690", "catalyst" ] ], "additional_components": [ "F6R5E4", "ENSBTAT00000006518", "ENSBTAT00000006518", "F6R5E4", "ENSBTAT00000006518" ] }, "reaction_10051465": { "compartment": "compartment_7660", "id": "reaction_10051465", "reactome": "R-BTA-606349", "name": "Mis18 complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051445", "species_10051395" ], "products": [ "species_10051453" ], "modifiers": [], "additional_components": [ "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256" ] }, "reaction_10051451": { "compartment": "compartment_7660", "id": "reaction_10051451", "reactome": "R-BTA-606287", "name": "RSF complex binds the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051447", "species_10051335" ], "products": [ "species_10051431", "species_10051445", "species_10051449" ], "modifiers": [], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "A0A3Q1LP30", "ENSBTAT00000083436", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10051461": { "compartment": "compartment_7660", "id": "reaction_10051461", "reactome": "R-BTA-606289", "name": "New CENPA-containing nucleosomes are deposited at the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035218", "species_10051459", "species_10035105" ], "products": [ "species_10051447" ], "modifiers": [], "additional_components": [ "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10051463": { "compartment": "compartment_7660", "id": "reaction_10051463", "reactome": "R-BTA-606326", "name": "HJURP:CENPA complex localizes to the centromere", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051457", "species_10051453" ], "products": [ "species_10051459" ], "modifiers": [], "additional_components": [ "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "A0A3Q1M302", "ENSBTAT00000068526", "A8WFK5", "ENSBTAT00000048435", "F1MLG9", "ENSBTAT00000061053", "Q5EA18", "ENSBTAT00000009094", "Q2NKU0", "ENSBTAT00000005369", "Q08DW5", "ENSBTAT00000027600", "E1BAK5", "ENSBTAT00000001748", "G3MXW4", "ENSBTAT00000064627", "A0A3Q1M6A8", "ENSBTAT00000083119", "Q3ZBK8", "ENSBTAT00000032953", "A7YWP8", "ENSBTAT00000068875", "Q2TBR7", "ENSBTAT00000017996", "A0A3Q1LTH6", "ENSBTAT00000039939", "E1BMQ3", "ENSBTAT00000003380", "A5D7N9", "ENSBTAT00000022106", "E1BAL2", "ENSBTAT00000014256", "E1BB33", "ENSBTAT00000042677", "E1BCL3", "ENSBTAT00000053056", "F1MTV9", "ENSBTAT00000053056", "A0A3Q1LR94", "ENSBTAT00000053056", "A0A3Q1LXL7", "ENSBTAT00000054559", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "G5E613", "ENSBTAT00000049496", "A7MBG8", "ENSBTAT00000027964", "Q3MHL3", "ENSBTAT00000007758" ] }, "reaction_10058792": { "compartment": "compartment_70101", "id": "reaction_10058792", "reactome": "R-BTA-1475436", "name": "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058787", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "F1N0H3", "ENSBTAT00000023581" ] }, "reaction_10057070": { "compartment": "compartment_70101", "id": "reaction_10057070", "reactome": "R-BTA-1247668", "name": "Hemoglobin A binds O2, releasing H+ and CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057060", "species_29368" ], "products": [ "species_10057046", "species_70106", "species_113528" ], "modifiers": [], "additional_components": [ "species_71185", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533", "P02070", "ENSBTAT00000057323" ] }, "reaction_10063560": { "compartment": "compartment_7660", "id": "reaction_10063560", "reactome": "R-BTA-2065539", "name": "SREBP1A,1C,2:Importin beta-1 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043501", "species_10060344" ], "products": [ "species_10063558", "species_10060342" ], "modifiers": [], "additional_components": [ "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "G5E619", "ENSBTAT00000033457", "G3MZP2", "ENSBTAT00000033457", "species_29438", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063562": { "compartment": "compartment_70101", "id": "reaction_10063562", "reactome": "R-BTA-2065549", "name": "SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060328" ], "products": [ "species_10060330" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10060346": { "compartment": "compartment_70101", "id": "reaction_10060346", "reactome": "R-BTA-1655831", "name": "SREBP1A,1C,2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060332" ], "products": [ "species_10060344" ], "modifiers": [], "additional_components": [ "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650", "E1BFV0", "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956" ] }, "reaction_10063564": { "compartment": "compartment_70101", "id": "reaction_10063564", "reactome": "R-BTA-2065550", "name": "SREBP1A,1C,2 binds Importin beta-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044128", "species_10060330" ], "products": [ "species_10060332" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008650", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "A0A3Q1M285", "ENSBTAT00000072870", "F1ML06", "ENSBTAT00000018956", "E1BFV0", "ENSBTAT00000008650" ] }, "reaction_10090604": { "compartment": "compartment_17951", "id": "reaction_10090604", "reactome": "R-BTA-9033520", "name": "TYSND1 cleaves TYSND1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_10090597" ], "products": [ "species_10090599", "species_10090601" ], "modifiers": [ [ "species_10090597", "catalyst" ] ], "additional_components": [ "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816", "ENSBTAT00000052816" ] }, "reaction_10037293": { "compartment": "compartment_70101", "id": "reaction_10037293", "reactome": "R-BTA-114392", "name": "Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037287" ], "products": [ "species_10037229", "species_10037291" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10090504": { "compartment": "compartment_70101", "id": "reaction_10090504", "reactome": "R-BTA-9027532", "name": "PTGS2 dimer oxidises DHA to 13-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027547" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090506": { "compartment": "compartment_70101", "id": "reaction_10090506", "reactome": "R-BTA-9027607", "name": "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9608444", "species_29368" ], "products": [ "species_9027614" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090508": { "compartment": "compartment_70101", "id": "reaction_10090508", "reactome": "R-BTA-9027627", "name": "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9027622" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090510": { "compartment": "compartment_70101", "id": "reaction_10090510", "reactome": "R-BTA-9028255", "name": "PTGS2 dimer oxidises EPA to PGH3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9028280" ], "modifiers": [ [ "species_10065205", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10075037": { "compartment": "compartment_7660", "id": "reaction_10075037", "reactome": "R-BTA-5685953", "name": "SIRT6 deacetylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075030", "species_427523" ], "products": [ "species_427497", "species_427498", "species_10074778" ], "modifiers": [ [ "species_10075034", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "A0A3Q1NLY2", "ENSBTAT00000085498", "ENSBTAT00000026521" ] }, "reaction_10074798": { "compartment": "compartment_7660", "id": "reaction_10074798", "reactome": "R-BTA-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074795" ], "products": [ "species_113582", "species_10074789" ], "modifiers": [ [ "species_10074795", "catalyst" ] ], "additional_components": [ "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076339": { "compartment": "compartment_7660", "id": "reaction_10076339", "reactome": "R-BTA-5693608", "name": "Initial resection of double-strand break ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10076336" ], "products": [ "species_30555", "species_10075051" ], "modifiers": [ [ "species_10076336", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1NLY2", "ENSBTAT00000085498", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1NLY2", "ENSBTAT00000085498" ] }, "reaction_10060476": { "compartment": "compartment_12045", "id": "reaction_10060476", "reactome": "R-BTA-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10060456", "catalyst" ] ], "additional_components": [ "ENSBTAT00000047316" ] }, "reaction_10083369": { "compartment": "compartment_876", "id": "reaction_10083369", "reactome": "R-BTA-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10083366", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015375" ] }, "reaction_10083211": { "compartment": "compartment_12045", "id": "reaction_10083211", "reactome": "R-BTA-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6814253" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10083208", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084401" ] }, "reaction_10082931": { "compartment": "compartment_172574", "id": "reaction_10082931", "reactome": "R-BTA-6810392", "name": "TMEM55B translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082927" ], "products": [ "species_10082929" ], "modifiers": [], "additional_components": [ "ENSBTAT00000003561", "ENSBTAT00000003561" ] }, "reaction_10083092": { "compartment": "compartment_7660", "id": "reaction_10083092", "reactome": "R-BTA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_29358" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10083089", "catalyst" ] ], "additional_components": [ "F1MHT2", "ENSBTAT00000008517", "F1MHR4", "ENSBTAT00000024007" ] }, "reaction_10082934": { "compartment": "compartment_7660", "id": "reaction_10082934", "reactome": "R-BTA-6810410", "name": "PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_6810412" ], "products": [ "species_6810408", "species_113550" ], "modifiers": [ [ "species_10082929", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003561" ] }, "reaction_10060569": { "compartment": "compartment_876", "id": "reaction_10060569", "reactome": "R-BTA-1676109", "name": "PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060566", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "E1B8D1", "ENSBTAT00000043102", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845", "F1MBU9", "ENSBTAT00000017388", "species_113527" ] }, "reaction_10060473": { "compartment": "compartment_876", "id": "reaction_10060473", "reactome": "R-BTA-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_1806240", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082136": { "compartment": "compartment_70101", "id": "reaction_10082136", "reactome": "R-BTA-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10082128" ], "products": [ "species_10082134" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000050192", "F1ME94", "ENSBTAT00000050192", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060600": { "compartment": "compartment_876", "id": "reaction_10060600", "reactome": "R-BTA-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10085784": { "compartment": "compartment_171062", "id": "reaction_10085784", "reactome": "R-BTA-8871376", "name": "p-Y281,292-RUFY1 binds PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085767", "species_1806200" ], "products": [ "species_10085782" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "species_5693050", "F6R352", "ENSBTAT00000000317" ] }, "reaction_10060572": { "compartment": "compartment_876", "id": "reaction_10060572", "reactome": "R-BTA-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_1806224", "species_29370" ], "modifiers": [ [ "species_10060470", "catalyst" ] ], "additional_components": [ "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060595": { "compartment": "compartment_876", "id": "reaction_10060595", "reactome": "R-BTA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10060592", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BLB5", "ENSBTAT00000022635" ] }, "reaction_10085780": { "compartment": "compartment_70101", "id": "reaction_10085780", "reactome": "R-BTA-8871373", "name": "BMX phosphorylates RUFY1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10085777" ], "products": [ "species_29370", "species_10085773" ], "modifiers": [ [ "species_10044855", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317", "ENSBTAT00000000488" ] }, "reaction_10060535": { "compartment": "compartment_876", "id": "reaction_10060535", "reactome": "R-BTA-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10060532", "catalyst" ] ], "additional_components": [ "A0A3Q1LMW0", "ENSBTAT00000074360", "A0A3Q1LYK5", "ENSBTAT00000069408", "A0A3Q1LZ59", "ENSBTAT00000084980" ] }, "reaction_10082152": { "compartment": "compartment_876", "id": "reaction_10082152", "reactome": "R-BTA-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806224" ], "products": [ "species_29372", "species_1806240" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10082155": { "compartment": "compartment_876", "id": "reaction_10082155", "reactome": "R-BTA-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_29372", "species_426658" ], "modifiers": [ [ "species_10082149", "catalyst" ] ], "additional_components": [ "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852", "F1ME94", "ENSBTAT00000050192" ] }, "reaction_10060429": { "compartment": "compartment_876", "id": "reaction_10060429", "reactome": "R-BTA-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060426", "catalyst" ] ], "additional_components": [ "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10060461": { "compartment": "compartment_876", "id": "reaction_10060461", "reactome": "R-BTA-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10085775": { "compartment": "compartment_70101", "id": "reaction_10085775", "reactome": "R-BTA-8871370", "name": "p-Y281,292-RUFY1 translocates from cytosol to early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085773" ], "products": [ "species_10085767" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000317", "ENSBTAT00000000317" ] }, "reaction_10060590": { "compartment": "compartment_876", "id": "reaction_10060590", "reactome": "R-BTA-1676164", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_202247" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10085697": { "compartment": "compartment_876", "id": "reaction_10085697", "reactome": "R-BTA-8870489", "name": "PLEKHA4,(5,6) bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_10085693" ], "products": [ "species_10085695" ], "modifiers": [], "additional_components": [ "E1B7V8", "ENSBTAT00000061135", "E1B7V8", "ENSBTAT00000061135", "species_5693050" ] }, "reaction_10060579": { "compartment": "compartment_876", "id": "reaction_10060579", "reactome": "R-BTA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10060576", "catalyst" ] ], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "A0A3Q1MBL1", "ENSBTAT00000076329", "A6QLC5", "ENSBTAT00000008015", "F1N7M1", "ENSBTAT00000080996" ] }, "reaction_10082147": { "compartment": "compartment_70101", "id": "reaction_10082147", "reactome": "R-BTA-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10082132", "species_10060526" ], "products": [ "species_10082145" ], "modifiers": [], "additional_components": [ "ENSBTAT00000004852", "ENSBTAT00000069408", "A0A3Q1LYK5", "ENSBTAT00000069408", "A7MB43", "ENSBTAT00000004852" ] }, "reaction_10060514": { "compartment": "compartment_876", "id": "reaction_10060514", "reactome": "R-BTA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179838" ], "products": [ "species_29372", "species_202247" ], "modifiers": [ [ "species_10060511", "catalyst" ] ], "additional_components": [ "A6QNM5", "ENSBTAT00000015257", "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10060550": { "compartment": "compartment_876", "id": "reaction_10060550", "reactome": "R-BTA-1676048", "name": "PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10060547", "catalyst" ] ], "additional_components": [ "P32871", "ENSBTAT00000072391", "P23726", "ENSBTAT00000003033", "F1MDQ5", "ENSBTAT00000003878", "F1MYM3", "ENSBTAT00000009083", "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10083800": { "compartment": "compartment_70101", "id": "reaction_10083800", "reactome": "R-BTA-8849969", "name": "PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_8849959" ], "products": [ "species_29372", "species_8849958" ], "modifiers": [ [ "species_10083797", "catalyst" ] ], "additional_components": [ "species_179838", "species_1806238", "species_6810412", "species_5693050", "species_1806205", "species_1806259", "ENSBTAT00000029059" ] }, "reaction_10060588": { "compartment": "compartment_171062", "id": "reaction_10060588", "reactome": "R-BTA-1676162", "name": "PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806238" ], "products": [ "species_29372", "species_1806200" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10060558": { "compartment": "compartment_171062", "id": "reaction_10060558", "reactome": "R-BTA-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806205" ], "products": [ "species_29372", "species_1806259" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060574": { "compartment": "compartment_171062", "id": "reaction_10060574", "reactome": "R-BTA-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_29372", "species_1806199" ], "modifiers": [ [ "species_10060465", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078957" ] }, "reaction_10060501": { "compartment": "compartment_171062", "id": "reaction_10060501", "reactome": "R-BTA-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060518": { "compartment": "compartment_171062", "id": "reaction_10060518", "reactome": "R-BTA-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_1806180", "species_29370" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060614": { "compartment": "compartment_171062", "id": "reaction_10060614", "reactome": "R-BTA-1676206", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806180", "species_113592" ], "products": [ "species_29370", "species_1806238" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10060611": { "compartment": "compartment_20699", "id": "reaction_10060611", "reactome": "R-BTA-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060608", "catalyst" ] ], "additional_components": [ "A0A3Q1MHQ7", "ENSBTAT00000081928" ] }, "reaction_10060483": { "compartment": "compartment_20699", "id": "reaction_10060483", "reactome": "R-BTA-1675824", "name": "PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806165", "species_29356" ], "products": [ "species_29372", "species_1806217" ], "modifiers": [ [ "species_10060480", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001784" ] }, "reaction_10060498": { "compartment": "compartment_20699", "id": "reaction_10060498", "reactome": "R-BTA-1675928", "name": "PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806217" ], "products": [ "species_1806230", "species_29370" ], "modifiers": [ [ "species_10060495", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627", "E1B8D1", "ENSBTAT00000043102" ] }, "reaction_10060597": { "compartment": "compartment_20699", "id": "reaction_10060597", "reactome": "R-BTA-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10060458", "catalyst" ] ], "additional_components": [ "F1MK34", "ENSBTAT00000047316", "A6QLN5", "ENSBTAT00000002604" ] }, "reaction_10060516": { "compartment": "compartment_20699", "id": "reaction_10060516", "reactome": "R-BTA-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524146" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10060489", "catalyst" ] ], "additional_components": [ "species_74016", "species_29926", "E1BE68", "ENSBTAT00000046627" ] }, "reaction_10085843": { "compartment": "compartment_437051", "id": "reaction_10085843", "reactome": "R-BTA-8874470", "name": "TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8874484" ], "products": [ "species_8874460" ], "modifiers": [ [ "species_10085840", "catalyst" ] ], "additional_components": [ "species_179838", "species_6810412", "species_6810412", "species_179838", "A0A3Q1LVF0", "ENSBTAT00000072298" ] }, "reaction_10040152": { "compartment": "compartment_70101", "id": "reaction_10040152", "reactome": "R-BTA-176664", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176575", "species_158471" ], "products": [ "species_176501", "species_158466" ], "modifiers": [ [ "species_10040149", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040120": { "compartment": "compartment_70101", "id": "reaction_10040120", "reactome": "R-BTA-176588", "name": "lithocholate + PAPS => lithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_158471" ], "products": [ "species_176555", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040122": { "compartment": "compartment_70101", "id": "reaction_10040122", "reactome": "R-BTA-176604", "name": "taurolithocholate + PAPS => taurolithocholate sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176565", "species_158471" ], "products": [ "species_176483", "species_158466" ], "modifiers": [ [ "species_10040087", "catalyst" ] ], "additional_components": [ "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040157": { "compartment": "compartment_70101", "id": "reaction_10040157", "reactome": "R-BTA-176669", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176566" ], "products": [ "species_176500", "species_158466" ], "modifiers": [ [ "species_10040154", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388" ] }, "reaction_10076799": { "compartment": "compartment_70101", "id": "reaction_10076799", "reactome": "R-BTA-5695964", "name": "ABHD14B hydrolyses PNPB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695960", "species_29356" ], "products": [ "species_5695950", "species_76179" ], "modifiers": [ [ "species_10076796", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024782" ] }, "reaction_10038320": { "compartment": "compartment_70101", "id": "reaction_10038320", "reactome": "R-BTA-158860", "name": "SULT1A1 dimer sulfonates NHABP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158847", "species_158471" ], "products": [ "species_158859", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040112": { "compartment": "compartment_70101", "id": "reaction_10040112", "reactome": "R-BTA-176517", "name": "SULTs transfer (SO4)2- group to PREG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_158471" ], "products": [ "species_176665", "species_158466" ], "modifiers": [ [ "species_10040109", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040147": { "compartment": "compartment_70101", "id": "reaction_10040147", "reactome": "R-BTA-176646", "name": "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5695950", "species_158471" ], "products": [ "species_176600", "species_158466" ], "modifiers": [ [ "species_10040144", "catalyst" ] ], "additional_components": [ "A0A3Q1MP36", "ENSBTAT00000072780", "P50227", "ENSBTAT00000011388" ] }, "reaction_10040115": { "compartment": "compartment_70101", "id": "reaction_10040115", "reactome": "R-BTA-176521", "name": "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176619", "species_158471" ], "products": [ "species_176492", "species_158466" ], "modifiers": [ [ "species_10040075", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862" ] }, "reaction_10040117": { "compartment": "compartment_70101", "id": "reaction_10040117", "reactome": "R-BTA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176667", "species_158471" ], "products": [ "species_176564", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038231": { "compartment": "compartment_70101", "id": "reaction_10038231", "reactome": "R-BTA-158468", "name": "SULT1A1 dimer sulfonates PARA to PARA-SO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158469", "species_158471" ], "products": [ "species_158472", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088617": { "compartment": "compartment_17963", "id": "reaction_10088617", "reactome": "R-BTA-8954262", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_741440", "species_10088606" ], "products": [ "species_742343", "species_10088610" ], "modifiers": [ [ "species_10088614", "catalyst" ] ], "additional_components": [ "ENSBTAT00000043559", "ENSBTAT00000043559", "ENSBTAT00000000502" ] }, "reaction_10040136": { "compartment": "compartment_70101", "id": "reaction_10040136", "reactome": "R-BTA-176631", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176626" ], "products": [ "species_176496", "species_158466" ], "modifiers": [ [ "species_10040133", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187", "Q3ZC30", "ENSBTAT00000015862", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10040107": { "compartment": "compartment_70101", "id": "reaction_10040107", "reactome": "R-BTA-176494", "name": "SULTs transfer (SO4)2- group to 27HCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176617", "species_158471" ], "products": [ "species_176502", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10038318": { "compartment": "compartment_70101", "id": "reaction_10038318", "reactome": "R-BTA-158849", "name": "Phenol can form a sulfate conjugate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158858", "species_158471" ], "products": [ "species_158466", "species_158850" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10040129": { "compartment": "compartment_70101", "id": "reaction_10040129", "reactome": "R-BTA-176606", "name": "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_158466" ], "products": [ "species_29372", "species_76577" ], "modifiers": [ [ "species_10040126", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005311" ] }, "reaction_10040131": { "compartment": "compartment_70101", "id": "reaction_10040131", "reactome": "R-BTA-176609", "name": "cholesterol + PAPS => cholesterol sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176478", "species_158471" ], "products": [ "species_176618", "species_158466" ], "modifiers": [ [ "species_10040104", "catalyst" ] ], "additional_components": [ "A1A4N6", "ENSBTAT00000063187" ] }, "reaction_10040098": { "compartment": "compartment_70101", "id": "reaction_10040098", "reactome": "R-BTA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_176486" ], "products": [ "species_176519", "species_158466" ], "modifiers": [ [ "species_10040095", "catalyst" ] ], "additional_components": [ "Q3ZC30", "ENSBTAT00000015862", "F1MZX9", "ENSBTAT00000011474", "F1MBP4", "ENSBTAT00000003629", "P50227", "ENSBTAT00000011388", "E1BG19", "ENSBTAT00000031917", "F1N0S6", "ENSBTAT00000028234" ] }, "reaction_10038340": { "compartment": "compartment_70101", "id": "reaction_10038340", "reactome": "R-BTA-159358", "name": "SULT1A3,4 dimers sulfate DA to DAOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158471", "species_159362" ], "products": [ "species_159352", "species_158466" ], "modifiers": [ [ "species_10038228", "catalyst" ] ], "additional_components": [ "P50227", "ENSBTAT00000011388" ] }, "reaction_10088580": { "compartment": "compartment_17963", "id": "reaction_10088580", "reactome": "R-BTA-8953499", "name": "IMPAD1 hydrolyses PAP to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742343", "species_2022884" ], "products": [ "species_8851226", "species_8953493" ], "modifiers": [ [ "species_10088577", "catalyst" ], [ "species_8953505", "inhibitor" ] ], "additional_components": [ "species_29926", "A0A452DIR7", "ENSBTAT00000020766" ] }, "reaction_10050342": { "compartment": "compartment_70101", "id": "reaction_10050342", "reactome": "R-BTA-450434", "name": "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450444", "species_10050336" ], "products": [ "species_10050340" ], "modifiers": [], "additional_components": [ "A0A3Q1M8I4", "ENSBTAT00000075547", "A0A3Q1M8I4", "ENSBTAT00000075547" ] }, "reaction_10082923": { "compartment": "compartment_7660", "id": "reaction_10082923", "reactome": "R-BTA-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810408", "species_10069400" ], "products": [ "species_10082921" ], "modifiers": [], "additional_components": [ "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "species_1806259" ] }, "reaction_10086155": { "compartment": "compartment_7660", "id": "reaction_10086155", "reactome": "R-BTA-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086151", "species_10053086" ], "products": [ "species_10086153" ], "modifiers": [], "additional_components": [ "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517", "ENSBTAT00000022592", "Q5BIN5", "ENSBTAT00000022592", "F1MHR4", "ENSBTAT00000024007", "F1MHT2", "ENSBTAT00000008517" ] }, "reaction_10083072": { "compartment": "compartment_7660", "id": "reaction_10083072", "reactome": "R-BTA-6811479", "name": "ING2 recruits EP300 to TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10053052", "species_10069400" ], "products": [ "species_10083070" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000021556", "ENSBTAT00000066213", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10083077": { "compartment": "compartment_7660", "id": "reaction_10083077", "reactome": "R-BTA-6811508", "name": "ING2-bound EP300 acetylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10083070" ], "products": [ "species_2485002", "species_10083074" ], "modifiers": [ [ "species_10083070", "catalyst" ], [ "species_6810408", "catalyst" ] ], "additional_components": [ "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "G3MY31", "ENSBTAT00000066213", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420" ] }, "reaction_10090593": { "compartment": "compartment_70101", "id": "reaction_10090593", "reactome": "R-BTA-9033232", "name": "PEX7 binds cargo proteins containing PTS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090579", "species_10090589" ], "products": [ "species_10090591" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022338", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "A0A3Q1NBU3", "ENSBTAT00000081070", "O18778", "ENSBTAT00000010126", "Q3ZC41", "ENSBTAT00000024335", "Q08DL6", "ENSBTAT00000022338" ] }, "reaction_10090770": { "compartment": "compartment_70101", "id": "reaction_10090770", "reactome": "R-BTA-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10090766", "species_10090732" ], "products": [ "species_10090768" ], "modifiers": [], "additional_components": [ "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885", "ENSBTAT00000009921", "Q3SZD1", "ENSBTAT00000009921", "A4FUD4", "ENSBTAT00000026285", "A0A3Q1M1S5", "ENSBTAT00000047447", "A0A3Q1MTZ2", "ENSBTAT00000074727", "Q148K5", "ENSBTAT00000011022", "Q2KJ57", "ENSBTAT00000027382", "A0A3Q1LJ52", "ENSBTAT00000070862", "A0A3Q1MSZ7", "ENSBTAT00000082884", "A6QQZ0", "ENSBTAT00000016739", "A0A452DI69", "ENSBTAT00000009885" ] }, "reaction_10039049": { "compartment": "compartment_5460", "id": "reaction_10039049", "reactome": "R-BTA-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_10039037" ], "products": [ "species_10039039" ], "modifiers": [], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039044": { "compartment": "compartment_5460", "id": "reaction_10039044", "reactome": "R-BTA-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039039" ], "products": [ "species_10039041", "species_113521" ], "modifiers": [ [ "species_10039039", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_29370", "species_29372" ] }, "reaction_10039047": { "compartment": "compartment_5460", "id": "reaction_10039047", "reactome": "R-BTA-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10039041", "species_163953" ], "products": [ "species_113529", "species_113593", "species_10039037" ], "modifiers": [ [ "species_10039041", "catalyst" ] ], "additional_components": [ "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "A0A452DII8", "ENSBTAT00000017710", "P05631", "ENSBTAT00000081996", "P05630", "ENSBTAT00000000721", "P05632", "ENSBTAT00000085877", "P03929", "ENSBTAT00000060553", "A0A3Q1MP66", "ENSBTAT00000072644", "P00847", "ENSBTAT00000060539", "Q3ZC75", "ENSBTAT00000003832", "P13620", "ENSBTAT00000074726", "A0A3Q1M7G3", "ENSBTAT00000077018", "A0A3Q1MCR1", "ENSBTAT00000077018", "A0A3Q1N4G2", "ENSBTAT00000077018", "Q00361", "ENSBTAT00000023255", "A0A0N4STN0", "ENSBTAT00000009643", "A0A452DI29", "ENSBTAT00000007538", "P32876", "ENSBTAT00000024402", "P13621", "ENSBTAT00000024326", "species_113592" ] }, "reaction_10035417": { "compartment": "compartment_5460", "id": "reaction_10035417", "reactome": "R-BTA-74181", "name": "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_73871" ], "products": [ "species_113559" ], "modifiers": [ [ "species_10033821", "catalyst" ] ], "additional_components": [ "Q29RZ0", "ENSBTAT00000017122" ] }, "reaction_10035374": { "compartment": "compartment_5460", "id": "reaction_10035374", "reactome": "R-BTA-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_73911" ], "products": [ "species_113529", "species_73909", "species_29362" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10035415": { "compartment": "compartment_5460", "id": "reaction_10035415", "reactome": "R-BTA-74177", "name": "OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_73909" ], "products": [ "species_73871", "species_113536" ], "modifiers": [ [ "species_10035412", "catalyst" ] ], "additional_components": [ "A0A3Q1LIX4", "ENSBTAT00000077723" ] }, "reaction_10065944": { "compartment": "compartment_2514888", "id": "reaction_10065944", "reactome": "R-BTA-2632521", "name": "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035617" ], "products": [ "species_10065942", "species_2466098" ], "modifiers": [], "additional_components": [ "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10035596": { "compartment": "compartment_2514888", "id": "reaction_10035596", "reactome": "R-BTA-74885", "name": "GUCYs converts GTP to cGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438" ], "products": [ "species_111294", "species_30991" ], "modifiers": [ [ "species_10035583", "catalyst" ], [ "species_10035592", "catalyst" ], [ "species_10035594", "inhibitor" ], [ "species_10035590", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000011564", "ENSBTAT00000087322", "P46065", "ENSBTAT00000087322", "species_74016", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10065808": { "compartment": "compartment_70101", "id": "reaction_10065808", "reactome": "R-BTA-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065796", "species_2534019" ], "products": [ "species_10065799", "species_76194" ], "modifiers": [ [ "species_10065805", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023990", "ENSBTAT00000023990", "Q9N181", "ENSBTAT00000050460", "F1MZK0", "ENSBTAT00000007950" ] }, "reaction_10035619": { "compartment": "compartment_2514888", "id": "reaction_10035619", "reactome": "R-BTA-74948", "name": "PP2A dephosphorylates p-RHO to RHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10035601" ], "products": [ "species_29372", "species_2565923" ], "modifiers": [ [ "species_10035607", "catalyst" ], [ "species_74016", "catalyst" ], [ "species_10035617", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000001730", "ENSBTAT00000001730", "species_29926", "F1MBQ1", "ENSBTAT00000068795", "A0A3Q1MAN7", "ENSBTAT00000077886", "P02699", "ENSBTAT00000001730" ] }, "reaction_10065940": { "compartment": "compartment_70101", "id": "reaction_10065940", "reactome": "R-BTA-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035588", "species_74016" ], "products": [ "species_10035590" ], "modifiers": [], "additional_components": [ "ENSBTAT00000087322", "species_74016", "P46065", "ENSBTAT00000087322" ] }, "reaction_10078600": { "compartment": "compartment_876", "id": "reaction_10078600", "reactome": "R-BTA-6797974", "name": "LRRTMs bind NRXNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078596", "species_10078418" ], "products": [ "species_10078598" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078488": { "compartment": "compartment_70101", "id": "reaction_10078488", "reactome": "R-BTA-6797553", "name": "Protein 4.1 binds CASK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078484", "species_10071423" ], "products": [ "species_10078486" ], "modifiers": [], "additional_components": [ "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "ENSBTAT00000071329", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078522": { "compartment": "compartment_876", "id": "reaction_10078522", "reactome": "R-BTA-6797568", "name": "NRXNs bind CASK:Protein 4.1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078486", "species_10078444" ], "products": [ "species_10078520" ], "modifiers": [], "additional_components": [ "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1LPV4", "ENSBTAT00000071329", "A0A3Q1LWK1", "ENSBTAT00000075847", "E1B7S3", "ENSBTAT00000061281" ] }, "reaction_10078446": { "compartment": "compartment_876", "id": "reaction_10078446", "reactome": "R-BTA-6794346", "name": "NRXNs bind NLGNs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078418", "species_10078442" ], "products": [ "species_10078444" ], "modifiers": [], "additional_components": [ "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956" ] }, "reaction_10078464": { "compartment": "compartment_876", "id": "reaction_10078464", "reactome": "R-BTA-6794347", "name": "Homer1,2,3 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078458", "species_10078456" ], "products": [ "species_10078462" ], "modifiers": [], "additional_components": [ "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078466": { "compartment": "compartment_876", "id": "reaction_10078466", "reactome": "R-BTA-6794355", "name": "Homer1,2,3 binds mGluR1a,5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10045110", "species_10078456" ], "products": [ "species_10078458" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085376", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "A0A3Q1LHC4", "ENSBTAT00000083397", "F1MW19", "ENSBTAT00000001076", "F1MDE0", "ENSBTAT00000085376" ] }, "reaction_10078518": { "compartment": "compartment_876", "id": "reaction_10078518", "reactome": "R-BTA-6797554", "name": "ABP1 binds SHANK proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078514", "species_10043423" ], "products": [ "species_10078516" ], "modifiers": [], "additional_components": [ "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330", "ENSBTAT00000023325", "A0A452DIT4", "ENSBTAT00000023325", "F1MM66", "ENSBTAT00000003326", "A0A3Q1MBH0", "ENSBTAT00000084144", "F6Q4B1", "ENSBTAT00000045228", "G3X7N7", "ENSBTAT00000040145", "F1N104", "ENSBTAT00000026987", "F1MMZ4", "ENSBTAT00000061495", "F1N119", "ENSBTAT00000026956", "A0A3Q1MV08", "ENSBTAT00000084157", "E1BBJ2", "ENSBTAT00000006420", "A0A3Q1LRW9", "ENSBTAT00000068330" ] }, "reaction_10046648": { "compartment": "compartment_70101", "id": "reaction_10046648", "reactome": "R-BTA-381727", "name": "RAP1A exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10046644" ], "products": [ "species_10046646", "species_29420" ], "modifiers": [ [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ] ], "additional_components": [ "species_29420", "P62833", "ENSBTAT00000068678", "P62833", "ENSBTAT00000068678", "species_29438", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046623": { "compartment": "compartment_876", "id": "reaction_10046623", "reactome": "R-BTA-381608", "name": "cAMP activates EPAC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044624", "species_30389" ], "products": [ "species_10044626" ], "modifiers": [], "additional_components": [ "ENSBTAT00000061074", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10046642": { "compartment": "compartment_876", "id": "reaction_10046642", "reactome": "R-BTA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046640" ], "products": [ "species_10046640" ], "modifiers": [], "additional_components": [ "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162", "E1BDC5", "ENSBTAT00000039169", "F1MJA9", "ENSBTAT00000018162" ] }, "reaction_10046630": { "compartment": "compartment_876", "id": "reaction_10046630", "reactome": "R-BTA-381668", "name": "cAMP activates EPAC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044630", "species_30389" ], "products": [ "species_10044632" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085533", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533" ] }, "reaction_10043885": { "compartment": "compartment_876", "id": "reaction_10043885", "reactome": "R-BTA-209738", "name": "VD3 binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209767", "species_10043881" ], "products": [ "species_10043883" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870" ] }, "reaction_10043903": { "compartment": "compartment_70101", "id": "reaction_10043903", "reactome": "R-BTA-209760", "name": "Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043895" ], "products": [ "species_10043901" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "A0A3Q1LQ02", "ENSBTAT00000075079", "F1MKV7", "ENSBTAT00000039417", "species_209804" ] }, "reaction_10088926": { "compartment": "compartment_984", "id": "reaction_10088926", "reactome": "R-BTA-8963851", "name": "VD3 dissociates from GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043883" ], "products": [ "species_209767", "species_10043881" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_8963870", "ENSBTAT00000075079" ] }, "reaction_10043984": { "compartment": "compartment_984", "id": "reaction_10043984", "reactome": "R-BTA-209944", "name": "25(OH)D binds GC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209906", "species_10043881" ], "products": [ "species_10043982" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075079", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10088928": { "compartment": "compartment_161320", "id": "reaction_10088928", "reactome": "R-BTA-8963864", "name": "CUBN dissociates from 25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044728" ], "products": [ "species_350136", "species_10043899" ], "modifiers": [], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "species_209804", "ENSBTAT00000039417" ] }, "reaction_10044739": { "compartment": "compartment_876", "id": "reaction_10044739", "reactome": "R-BTA-350168", "name": "LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044732" ], "products": [ "species_10043895" ], "modifiers": [ [ "species_10044736", "catalyst" ] ], "additional_components": [ "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000005988" ] }, "reaction_10044741": { "compartment": "compartment_984", "id": "reaction_10044741", "reactome": "R-BTA-350186", "name": "CUBN binds GC:25(OH)D", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043982", "species_10044730" ], "products": [ "species_10044732" ], "modifiers": [], "additional_components": [ "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804", "ENSBTAT00000039417", "F1MKV7", "ENSBTAT00000039417", "A0A3Q1LQ02", "ENSBTAT00000075079", "species_209804" ] }, "reaction_10043910": { "compartment": "compartment_70616", "id": "reaction_10043910", "reactome": "R-BTA-209765", "name": "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_209800", "species_29368", "species_29364" ], "products": [ "species_29356", "species_350159", "species_29366" ], "modifiers": [ [ "species_10043907", "catalyst" ], [ "species_29532", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003588" ] }, "reaction_10040922": { "compartment": "compartment_70101", "id": "reaction_10040922", "reactome": "R-BTA-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191265" ], "products": [ "species_111294", "species_191269", "species_29366" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10041664": { "compartment": "compartment_70101", "id": "reaction_10041664", "reactome": "R-BTA-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_195691", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_195655" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10041728": { "compartment": "compartment_70101", "id": "reaction_10041728", "reactome": "R-BTA-196417", "name": "Reduction of desmosterol to cholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_196420", "species_29364" ], "products": [ "species_193384", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041671": { "compartment": "compartment_12045", "id": "reaction_10041671", "reactome": "R-BTA-195690", "name": "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194691" ], "products": [ "species_195691" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10040892": { "compartment": "compartment_70101", "id": "reaction_10040892", "reactome": "R-BTA-191303", "name": "Another isopentenyl pyrophosphate is added to geranyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191409", "species_191362" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10040924": { "compartment": "compartment_70101", "id": "reaction_10040924", "reactome": "R-BTA-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_111294", "species_191265" ], "modifiers": [ [ "species_10040919", "catalyst" ] ], "additional_components": [ "species_29926", "Q6IE76", "ENSBTAT00000016504" ] }, "reaction_10040895": { "compartment": "compartment_70101", "id": "reaction_10040895", "reactome": "R-BTA-191322", "name": "Addition of isopentenyl pyrophosphate to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191324", "species_191362" ], "products": [ "species_111294", "species_191409" ], "modifiers": [ [ "species_10040889", "catalyst" ] ], "additional_components": [ "species_29926", "P56966", "ENSBTAT00000017376" ] }, "reaction_10041502": { "compartment": "compartment_70101", "id": "reaction_10041502", "reactome": "R-BTA-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194657", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194661", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10040913": { "compartment": "compartment_70101", "id": "reaction_10040913", "reactome": "R-BTA-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10040910", "catalyst" ] ], "additional_components": [ "A0A140T853", "ENSBTAT00000005323", "species_29926" ] }, "reaction_10040881": { "compartment": "compartment_70101", "id": "reaction_10040881", "reactome": "R-BTA-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_191269", "species_29364" ], "products": [ "species_191309", "species_29356", "species_29366" ], "modifiers": [ [ "species_10040878", "catalyst" ] ], "additional_components": [ "A5D9A8", "ENSBTAT00000007228", "species_113596" ] }, "reaction_10088019": { "compartment": "compartment_70101", "id": "reaction_10088019", "reactome": "R-BTA-8952137", "name": "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_191265" ], "products": [ "species_8952135", "species_29372" ], "modifiers": [ [ "species_10088016", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014674" ] }, "reaction_10041493": { "compartment": "compartment_13231", "id": "reaction_10041493", "reactome": "R-BTA-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194725", "species_194688" ], "products": [ "species_194668", "species_194704" ], "modifiers": [ [ "species_10041490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000011125" ] }, "reaction_10083496": { "compartment": "compartment_70101", "id": "reaction_10083496", "reactome": "R-BTA-8848215", "name": "ACAT2 condenses 2 Ac-CoA to form ACA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_191293", "species_29356", "species_76194" ], "modifiers": [ [ "species_10083493", "catalyst" ] ], "additional_components": [ "A0A3Q1MLP4", "ENSBTAT00000012548" ] }, "reaction_10040904": { "compartment": "compartment_70101", "id": "reaction_10040904", "reactome": "R-BTA-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191374", "species_70106", "species_29364" ], "products": [ "species_29366", "species_76194", "species_191424" ], "modifiers": [ [ "species_10040901", "catalyst" ] ], "additional_components": [ "A7Z064", "ENSBTAT00000010315" ] }, "reaction_10041484": { "compartment": "compartment_70101", "id": "reaction_10041484", "reactome": "R-BTA-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_113528", "species_194667", "species_73473" ], "modifiers": [ [ "species_10041481", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012167" ] }, "reaction_10041486": { "compartment": "compartment_70101", "id": "reaction_10041486", "reactome": "R-BTA-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_29364", "species_194723" ], "products": [ "species_29356", "species_29366", "species_194657" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10081986": { "compartment": "compartment_12045", "id": "reaction_10081986", "reactome": "R-BTA-6807052", "name": "EBP isomerizes ZYMSTNL to LTHSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807048" ], "products": [ "species_6807054" ], "modifiers": [ [ "species_10041668", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012234" ] }, "reaction_10081988": { "compartment": "compartment_12045", "id": "reaction_10081988", "reactome": "R-BTA-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_6807054", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_6807057" ], "modifiers": [ [ "species_10041661", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072112" ] }, "reaction_10081990": { "compartment": "compartment_12045", "id": "reaction_10081990", "reactome": "R-BTA-6807064", "name": "DHCR24 reduces ZYMOL to ZYMSTNL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194691" ], "products": [ "species_6807048", "species_29366" ], "modifiers": [ [ "species_10041725", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080856" ] }, "reaction_10041477": { "compartment": "compartment_70101", "id": "reaction_10041477", "reactome": "R-BTA-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_194644", "species_29364" ], "products": [ "species_194735", "species_29356", "species_29366" ], "modifiers": [ [ "species_10041474", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003991" ] }, "reaction_10038347": { "compartment": "compartment_70101", "id": "reaction_10038347", "reactome": "R-BTA-159425", "name": "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_194096" ], "products": [ "species_111294", "species_29356", "species_194073", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "species_193451", "CHEBI:16755", "species_192356", "CHEBI:28701", "ENSBTAT00000020170" ] }, "reaction_10041437": { "compartment": "compartment_876", "id": "reaction_10041437", "reactome": "R-BTA-194187", "name": "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041428", "species_192483", "species_74113" ], "products": [ "species_10041430", "species_83910" ], "modifiers": [ [ "species_10041434", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014054", "CHEBI:17687", "CHEBI:28865", "CHEBI:16755", "CHEBI:36274", "species_193451", "CHEBI:9407", "A0A452DID8", "ENSBTAT00000014054", "species_193451", "CHEBI:17687", "CHEBI:36274", "CHEBI:16525", "CHEBI:16755", "CHEBI:28865", "ENSBTAT00000021363" ] }, "reaction_10085806": { "compartment": "compartment_70101", "id": "reaction_10085806", "reactome": "R-BTA-8873850", "name": "STARD5 binds DCA, LCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_176655", "species_10085802", "species_5357505" ], "products": [ "species_10085804" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014559", "species_5357505", "A1A4M6", "ENSBTAT00000014559", "species_176655" ] }, "reaction_10085291": { "compartment": "compartment_70101", "id": "reaction_10085291", "reactome": "R-BTA-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10085288", "catalyst" ] ], "additional_components": [ "A0A3Q1LYV2", "ENSBTAT00000083446", "E1BBD8", "ENSBTAT00000017982", "E1BL67", "ENSBTAT00000044841", "A0A3Q1M0E7", "ENSBTAT00000066543", "A0A3Q1MW81", "ENSBTAT00000066543" ] }, "reaction_10041097": { "compartment": "compartment_70101", "id": "reaction_10041097", "reactome": "R-BTA-191972", "name": "27-hydroxycholesterol is 7alpha-hydroxylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_176617", "species_29368", "species_29364" ], "products": [ "species_29356", "species_29366", "species_192194" ], "modifiers": [ [ "species_10041094", "catalyst" ] ], "additional_components": [ "A0A3Q1NAD5", "ENSBTAT00000070426" ] }, "reaction_10041369": { "compartment": "compartment_70101", "id": "reaction_10041369", "reactome": "R-BTA-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193829", "species_29364" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041371": { "compartment": "compartment_70101", "id": "reaction_10041371", "reactome": "R-BTA-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192194" ], "products": [ "species_70106", "species_193835", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041373": { "compartment": "compartment_70101", "id": "reaction_10041373", "reactome": "R-BTA-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_9617026" ], "products": [ "species_193829", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041375": { "compartment": "compartment_70101", "id": "reaction_10041375", "reactome": "R-BTA-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041377": { "compartment": "compartment_70101", "id": "reaction_10041377", "reactome": "R-BTA-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041208": { "compartment": "compartment_70101", "id": "reaction_10041208", "reactome": "R-BTA-192137", "name": "THCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10041179": { "compartment": "compartment_5460", "id": "reaction_10041179", "reactome": "R-BTA-192054", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_113529", "species_191968", "species_113600" ], "products": [ "species_113563", "species_192161", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041210": { "compartment": "compartment_70101", "id": "reaction_10041210", "reactome": "R-BTA-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191980", "species_70106", "species_29364" ], "products": [ "species_192030", "species_29366" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041308": { "compartment": "compartment_17951", "id": "reaction_10041308", "reactome": "R-BTA-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_141343", "species_192356" ], "products": [ "species_193451", "species_193514" ], "modifiers": [ [ "species_10041305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074004" ] }, "reaction_10041310": { "compartment": "compartment_5460", "id": "reaction_10041310", "reactome": "R-BTA-193393", "name": "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193436", "species_113533", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193387", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041104": { "compartment": "compartment_5460", "id": "reaction_10041104", "reactome": "R-BTA-191999", "name": "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_192078", "species_113529", "species_113600" ], "products": [ "species_192201", "species_113563", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041170": { "compartment": "compartment_70101", "id": "reaction_10041170", "reactome": "R-BTA-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10041167", "catalyst" ] ], "additional_components": [ "E1BP71", "ENSBTAT00000039350" ] }, "reaction_10041301": { "compartment": "compartment_17951", "id": "reaction_10041301", "reactome": "R-BTA-193369", "name": "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_193442" ], "products": [ "species_113575", "species_193459" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041204": { "compartment": "compartment_70101", "id": "reaction_10041204", "reactome": "R-BTA-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_192114" ], "products": [ "species_70106", "species_192136", "species_73473" ], "modifiers": [ [ "species_10041201", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003028" ] }, "reaction_10041172": { "compartment": "compartment_5460", "id": "reaction_10041172", "reactome": "R-BTA-192042", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192201", "species_113563" ], "products": [ "species_113529", "species_191968", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041111": { "compartment": "compartment_70101", "id": "reaction_10041111", "reactome": "R-BTA-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_192136", "species_29364" ], "products": [ "species_191980", "species_29366" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041321": { "compartment": "compartment_70101", "id": "reaction_10041321", "reactome": "R-BTA-193424", "name": "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76194", "species_193505" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041323": { "compartment": "compartment_17951", "id": "reaction_10041323", "reactome": "R-BTA-193452", "name": "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193429" ], "products": [ "species_193442" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041226": { "compartment": "compartment_17951", "id": "reaction_10041226", "reactome": "R-BTA-192335", "name": "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113535", "species_192316" ], "products": [ "species_113575", "species_192342" ], "modifiers": [ [ "species_10041223", "catalyst" ] ], "additional_components": [ "species_113596", "F1MRF5", "ENSBTAT00000005472" ] }, "reaction_10041197": { "compartment": "compartment_70101", "id": "reaction_10041197", "reactome": "R-BTA-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10041108", "catalyst" ] ], "additional_components": [ "ENSBTAT00000002172" ] }, "reaction_10041325": { "compartment": "compartment_5460", "id": "reaction_10041325", "reactome": "R-BTA-193460", "name": "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113533", "species_193435", "species_113529", "species_113600" ], "products": [ "species_113563", "species_193440", "species_113521" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041327": { "compartment": "compartment_5460", "id": "reaction_10041327", "reactome": "R-BTA-193497", "name": "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113563", "species_193387" ], "products": [ "species_193435", "species_113529", "species_113600" ], "modifiers": [ [ "species_10041101", "catalyst" ] ], "additional_components": [ "ENSBTAT00000017935" ] }, "reaction_10041186": { "compartment": "compartment_17951", "id": "reaction_10041186", "reactome": "R-BTA-192056", "name": "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192308" ], "products": [ "species_192316" ], "modifiers": [ [ "species_10041183", "catalyst" ] ], "additional_components": [ "ENSBTAT00000029075" ] }, "reaction_10041317": { "compartment": "compartment_70101", "id": "reaction_10041317", "reactome": "R-BTA-193401", "name": "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192013", "species_113592", "species_76194" ], "products": [ "species_111294", "species_192096", "species_76577" ], "modifiers": [ [ "species_10041314", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078122" ] }, "reaction_10041319": { "compartment": "compartment_70101", "id": "reaction_10041319", "reactome": "R-BTA-193407", "name": "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_193505", "species_76194" ], "products": [ "species_111294", "species_193457", "species_76577" ], "modifiers": [ [ "species_10038344", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020170" ] }, "reaction_10085316": { "compartment": "compartment_70101", "id": "reaction_10085316", "reactome": "R-BTA-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_8868393", "species_1806234" ], "modifiers": [ [ "species_10049114", "catalyst" ] ], "additional_components": [ "ENSBTAT00000027095" ] }, "reaction_10076009": { "compartment": "compartment_7660", "id": "reaction_10076009", "reactome": "R-BTA-5691004", "name": "XPC binds RAD23 and CETN2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075366", "species_10069573", "species_10069565" ], "products": [ "species_10076007" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002506", "ENSBTAT00000080567", "ENSBTAT00000010319", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077396": { "compartment": "compartment_7660", "id": "reaction_10077396", "reactome": "R-BTA-6782943", "name": "UV-DDB ubiquitinates XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076069", "species_10036828" ], "products": [ "species_10077087" ], "modifiers": [ [ "species_10076069", "catalyst" ] ], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506" ] }, "reaction_10077108": { "compartment": "compartment_7660", "id": "reaction_10077108", "reactome": "R-BTA-5696655", "name": "PARP1 or PARP2 PARylates DDB2 and autoPARylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077089", "species_427523" ], "products": [ "species_427497", "species_10077106" ], "modifiers": [], "additional_components": [ "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LPC8", "ENSBTAT00000080567", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q2TBN3", "ENSBTAT00000010319", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740" ] }, "reaction_10076071": { "compartment": "compartment_7660", "id": "reaction_10076071", "reactome": "R-BTA-5691006", "name": "XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076007", "species_10076067", "species_5688114" ], "products": [ "species_10076069", "species_10076065" ], "modifiers": [], "additional_components": [ "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128", "A0A3Q1LNF8", "ENSBTAT00000075328", "A0A3Q1LKZ4", "ENSBTAT00000072958", "A0A3Q1MNL1", "ENSBTAT00000086637", "A0A452DJ09", "ENSBTAT00000028740", "Q2TBN3", "ENSBTAT00000010319", "A0A3Q1LPC8", "ENSBTAT00000080567", "Q29RK4", "ENSBTAT00000002506", "F1MBP8", "ENSBTAT00000003609", "F6QE33", "ENSBTAT00000014754", "Q2KI56", "ENSBTAT00000069661", "G3X736", "ENSBTAT00000025677", "A4FV74", "ENSBTAT00000007696", "A0A3Q1ME43", "ENSBTAT00000071522", "Q3SZA0", "ENSBTAT00000009128" ] }, "reaction_10077016": { "compartment": "compartment_7660", "id": "reaction_10077016", "reactome": "R-BTA-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10077009" ], "products": [ "species_10036828", "species_10036653" ], "modifiers": [ [ "species_10077013", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q1LZ75", "ENSBTAT00000023078", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000023078", "ENSBTAT00000067380" ] }, "reaction_10036661": { "compartment": "compartment_7660", "id": "reaction_10036661", "reactome": "R-BTA-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036657", "species_10036653" ], "products": [ "species_10036659" ], "modifiers": [], "additional_components": [ "ENSBTAT00000046336", "ENSBTAT00000023078", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336" ] }, "reaction_10037517": { "compartment": "compartment_70101", "id": "reaction_10037517", "reactome": "R-BTA-114600", "name": "Fyn/Lyn-mediated phosphorylation of FcR1 gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037504" ], "products": [ "species_29370", "species_10037514" ], "modifiers": [ [ "species_10037504", "catalyst" ] ], "additional_components": [ "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "P02453", "ENSBTAT00000017420" ] }, "reaction_10049071": { "compartment": "compartment_876", "id": "reaction_10049071", "reactome": "R-BTA-429497", "name": "SLP-76 stimulates PLC gamma 2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049069" ], "products": [ "species_10037554" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074574", "ENSBTAT00000074574" ] }, "reaction_10049395": { "compartment": "compartment_70101", "id": "reaction_10049395", "reactome": "R-BTA-437162", "name": "PI3K alpha, beta, gamma convert PIP2 to PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_179856" ], "products": [ "species_179838", "species_29370" ], "modifiers": [ [ "species_10047493", "catalyst" ] ], "additional_components": [ "A0A3Q1M2L5", "ENSBTAT00000080364", "E1BCV1", "ENSBTAT00000007845" ] }, "reaction_10049426": { "compartment": "compartment_70101", "id": "reaction_10049426", "reactome": "R-BTA-442291", "name": "VAV2 is a GEF for Rho/Rac family kinases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10049418" ], "products": [ "species_29420", "species_10049420" ], "modifiers": [ [ "species_10049423", "catalyst" ] ], "additional_components": [ "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29420", "Q1RMI2", "ENSBTAT00000000453", "P61585", "ENSBTAT00000005600", "species_29438", "ENSBTAT00000086853" ] }, "reaction_10037557": { "compartment": "compartment_70101", "id": "reaction_10037557", "reactome": "R-BTA-114689", "name": "PLC gamma 2-mediated PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10037554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074574" ] }, "reaction_10037588": { "compartment": "compartment_70101", "id": "reaction_10037588", "reactome": "R-BTA-139842", "name": "Binding of Syk tyrosine kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037584", "species_10037514" ], "products": [ "species_10037586" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168" ] }, "reaction_10050630": { "compartment": "compartment_70101", "id": "reaction_10050630", "reactome": "R-BTA-453183", "name": "p-Y348-SYK dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050628" ], "products": [ "species_10050626", "species_10037514" ], "modifiers": [], "additional_components": [ "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420", "A0A3Q1MHG9", "ENSBTAT00000075168", "ENSBTAT00000075168", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171", "Q9BDR7", "ENSBTAT00000034054", "G3MX19", "ENSBTAT00000065426", "P02453", "ENSBTAT00000017420" ] }, "reaction_10047475": { "compartment": "compartment_70101", "id": "reaction_10047475", "reactome": "R-BTA-392195", "name": "Gi activation by P2Y purinoceptor 12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10047470" ], "products": [ "species_29420", "species_10047472" ], "modifiers": [ [ "species_10047470", "catalyst" ] ], "additional_components": [ "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29438", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370", "species_29420", "Q3ZCA7", "ENSBTAT00000017303", "P63097", "ENSBTAT00000003515", "A7MBH9", "ENSBTAT00000027511", "G1K1V2", "ENSBTAT00000023234", "P63212", "ENSBTAT00000003959", "Q0IIL0", "ENSBTAT00000064076", "species_29370" ] }, "reaction_10049039": { "compartment": "compartment_70101", "id": "reaction_10049039", "reactome": "R-BTA-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10049037" ], "products": [ "species_29370", "species_10040563" ], "modifiers": [ [ "species_10036954", "catalyst" ] ], "additional_components": [ "ENSBTAT00000073013", "ENSBTAT00000073013", "F1N2V3", "ENSBTAT00000026624", "E1BA29", "ENSBTAT00000016160", "species_29438" ] }, "reaction_10047985": { "compartment": "compartment_70101", "id": "reaction_10047985", "reactome": "R-BTA-418662", "name": "Src activation following P2Y purinoceptor activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040957" ], "products": [ "species_10047983" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011767", "ENSBTAT00000011767" ] }, "reaction_10037201": { "compartment": "compartment_7660", "id": "reaction_10037201", "reactome": "R-BTA-112435", "name": "Formation of Elongin BC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037197", "species_10037193" ], "products": [ "species_10037199" ], "modifiers": [], "additional_components": [ "ENSBTAT00000026036", "ENSBTAT00000078734", "Q2KII4", "ENSBTAT00000078734", "Q3SZ32", "ENSBTAT00000026036" ] }, "reaction_10037185": { "compartment": "compartment_7660", "id": "reaction_10037185", "reactome": "R-BTA-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037181", "species_10037177" ], "products": [ "species_10037183" ], "modifiers": [], "additional_components": [ "ENSBTAT00000027214", "ENSBTAT00000073946", "A6QQT5", "ENSBTAT00000073946", "E1BNP8", "ENSBTAT00000027214" ] }, "reaction_10037187": { "compartment": "compartment_7660", "id": "reaction_10037187", "reactome": "R-BTA-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037108", "species_10037098" ], "products": [ "species_10037110" ], "modifiers": [], "additional_components": [ "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231", "ENSBTAT00000006162", "Q5EAB2", "ENSBTAT00000006162", "G3N172", "ENSBTAT00000063128", "A0A3Q1MA24", "ENSBTAT00000074231" ] }, "reaction_10037189": { "compartment": "compartment_7660", "id": "reaction_10037189", "reactome": "R-BTA-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037135", "species_10037130" ], "products": [ "species_10037137" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070366", "ENSBTAT00000071171", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366" ] }, "reaction_10037207": { "compartment": "compartment_7660", "id": "reaction_10037207", "reactome": "R-BTA-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037173" ], "products": [ "species_10037173" ], "modifiers": [], "additional_components": [ "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006", "A0A3Q1N7E3", "ENSBTAT00000071171", "A0A3Q1MQ76", "ENSBTAT00000070366", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "Q1JQ91", "ENSBTAT00000074897", "Q5E9B8", "ENSBTAT00000012481", "Q5EA53", "ENSBTAT00000027988", "Q2T9L9", "ENSBTAT00000078070", "Q32P79", "ENSBTAT00000007165", "Q32P78", "ENSBTAT00000043971", "Q3ZBC0", "ENSBTAT00000030510", "G3MZY8", "ENSBTAT00000069267", "Q3T0Q3", "ENSBTAT00000002420", "F2Z4H3", "ENSBTAT00000000606", "A0A3Q1MWS0", "ENSBTAT00000080412", "A6QQS5", "ENSBTAT00000023832", "G5E5S2", "ENSBTAT00000029144", "F1MW69", "ENSBTAT00000025006" ] }, "reaction_10081897": { "compartment": "compartment_70101", "id": "reaction_10081897", "reactome": "R-BTA-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081893" ], "products": [ "species_10081895" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086118", "ENSBTAT00000086118" ] }, "reaction_10037264": { "compartment": "compartment_17906", "id": "reaction_10037264", "reactome": "R-BTA-114307", "name": "Release of SMAC (DIABLO) from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037260" ], "products": [ "species_10037262" ], "modifiers": [ [ "species_10037235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005496", "ENSBTAT00000005496", "Q05KI7", "ENSBTAT00000000549" ] }, "reaction_10091186": { "compartment": "compartment_70101", "id": "reaction_10091186", "reactome": "R-BTA-9627106", "name": "SMAC (DIABLO) forms dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037262" ], "products": [ "species_10037285" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005496", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10049241": { "compartment": "compartment_876", "id": "reaction_10049241", "reactome": "R-BTA-432010", "name": "Aquaporin-1 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049243": { "compartment": "compartment_876", "id": "reaction_10049243", "reactome": "R-BTA-432054", "name": "Aquaporin-1 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049238", "catalyst" ] ], "additional_components": [ "P47865", "ENSBTAT00000000993" ] }, "reaction_10049262": { "compartment": "compartment_876", "id": "reaction_10049262", "reactome": "R-BTA-432067", "name": "Aquaporin-4 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10049259", "catalyst" ] ], "additional_components": [ "O77750", "ENSBTAT00000082069" ] }, "reaction_10049253": { "compartment": "compartment_876", "id": "reaction_10049253", "reactome": "R-BTA-432065", "name": "p-S256-Aquaporin-2 passively transports water into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10049250", "catalyst" ] ], "additional_components": [ "P79099", "ENSBTAT00000011024" ] }, "reaction_10049271": { "compartment": "compartment_876", "id": "reaction_10049271", "reactome": "R-BTA-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10049268", "catalyst" ] ], "additional_components": [ "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051145": { "compartment": "compartment_876", "id": "reaction_10051145", "reactome": "R-BTA-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051148": { "compartment": "compartment_876", "id": "reaction_10051148", "reactome": "R-BTA-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051150": { "compartment": "compartment_876", "id": "reaction_10051150", "reactome": "R-BTA-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10051119", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790" ] }, "reaction_10051136": { "compartment": "compartment_876", "id": "reaction_10051136", "reactome": "R-BTA-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10051141": { "compartment": "compartment_876", "id": "reaction_10051141", "reactome": "R-BTA-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10051138", "catalyst" ] ], "additional_components": [ "F1MNJ1", "ENSBTAT00000006790", "F1N3R5", "ENSBTAT00000026782" ] }, "reaction_10051143": { "compartment": "compartment_876", "id": "reaction_10051143", "reactome": "R-BTA-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10051133", "catalyst" ] ], "additional_components": [ "A0A3S5ZPM1", "ENSBTAT00000026884", "O77750", "ENSBTAT00000082069", "P06624", "ENSBTAT00000013360", "F1MNJ1", "ENSBTAT00000006790", "A0A3Q1LWN9", "ENSBTAT00000085930", "P79099", "ENSBTAT00000011024", "F1N3R5", "ENSBTAT00000026782", "P47865", "ENSBTAT00000000993" ] }, "reaction_10041050": { "compartment": "compartment_70101", "id": "reaction_10041050", "reactome": "R-BTA-191784", "name": "snRNA Cap hypermethylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041043" ], "products": [ "species_10041031" ], "modifiers": [ [ "species_10041047", "catalyst" ] ], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:2274", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000007749" ] }, "reaction_10041039": { "compartment": "compartment_70101", "id": "reaction_10041039", "reactome": "R-BTA-191763", "name": "snRNP:Snurportin complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041031", "species_10041035" ], "products": [ "species_10041037" ], "modifiers": [], "additional_components": [ "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604", "ENSBTAT00000076267", "Q2TBK8", "ENSBTAT00000076267", "E1BEK3", "ENSBTAT00000027878", "Q2KHW8", "ENSBTAT00000020624", "F1MRW7", "ENSBTAT00000024914", "Q17QA0", "ENSBTAT00000014112", "F1MAW0", "ENSBTAT00000017819", "O18870", "ENSBTAT00000007547", "E1BJG3", "ENSBTAT00000016037", "Q1LZ79", "ENSBTAT00000013582", "Q3ZBL0", "ENSBTAT00000007241", "A0A3Q1M973", "ENSBTAT00000001380", "A0A3Q1MM18", "ENSBTAT00000086549", "Q3ZC10", "ENSBTAT00000010912", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "CHEBI:1604" ] }, "reaction_10039916": { "compartment": "compartment_17957", "id": "reaction_10039916", "reactome": "R-BTA-174916", "name": "Formation of N-glucuronides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174932", "species_174384" ], "products": [ "species_158602", "species_174918" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "species_159154", "CHEBI:17688", "CHEBI:63860", "CHEBI:32663", "ENSBTAT00000076879" ] }, "reaction_10076785": { "compartment": "compartment_5460", "id": "reaction_10076785", "reactome": "R-BTA-5694563", "name": "ABHD10 hydrolyses MPAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694574", "species_113521" ], "products": [ "species_5694569", "species_5694565" ], "modifiers": [ [ "species_10076782", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006038" ] }, "reaction_10038336": { "compartment": "compartment_17957", "id": "reaction_10038336", "reactome": "R-BTA-159179", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159160", "species_174384" ], "products": [ "species_159149", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10038338": { "compartment": "compartment_17957", "id": "reaction_10038338", "reactome": "R-BTA-159194", "name": "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159151", "species_174384" ], "products": [ "species_159160", "species_158602" ], "modifiers": [ [ "species_10038333", "catalyst" ] ], "additional_components": [ "ENSBTAT00000076879" ] }, "reaction_10039749": { "compartment": "compartment_70101", "id": "reaction_10039749", "reactome": "R-BTA-173597", "name": "UDP-glucose is oxidised to UDP-glucuronate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29410", "species_29360" ], "products": [ "species_70106", "species_158601", "species_73473" ], "modifiers": [ [ "species_10039746", "catalyst" ] ], "additional_components": [ "P12378", "ENSBTAT00000019302" ] }, "reaction_10040682": { "compartment": "compartment_5460", "id": "reaction_10040682", "reactome": "R-BTA-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_70958", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10040679", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "A0A452DI36", "ENSBTAT00000005380" ] }, "reaction_10040654": { "compartment": "compartment_17927", "id": "reaction_10040654", "reactome": "R-BTA-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189411" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10040651", "catalyst" ] ], "additional_components": [ "E1BKY9", "ENSBTAT00000005398" ] }, "reaction_10040688": { "compartment": "compartment_70101", "id": "reaction_10040688", "reactome": "R-BTA-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190173", "species_10040669" ], "products": [ "species_10040686", "species_29426" ], "modifiers": [], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_29426", "Q58DK5", "ENSBTAT00000000315", "species_190173" ] }, "reaction_10040672": { "compartment": "compartment_70101", "id": "reaction_10040672", "reactome": "R-BTA-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_29356", "species_70106", "species_189464" ], "modifiers": [ [ "species_10040669", "catalyst" ] ], "additional_components": [ "species_29426", "Q58DK5", "ENSBTAT00000000315" ] }, "reaction_10066416": { "compartment": "compartment_5460", "id": "reaction_10066416", "reactome": "R-BTA-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189444", "species_2162257", "species_113521" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10066413", "catalyst" ] ], "additional_components": [ "ENSBTAT00000020336" ] }, "reaction_10040645": { "compartment": "compartment_70101", "id": "reaction_10040645", "reactome": "R-BTA-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_189464" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10040642", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q2KIN5", "ENSBTAT00000007052" ] }, "reaction_10040663": { "compartment": "compartment_17927", "id": "reaction_10040663", "reactome": "R-BTA-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10040660", "catalyst" ] ], "additional_components": [ "P56602", "ENSBTAT00000061124", "species_113596" ] }, "reaction_10038380": { "compartment": "compartment_5460", "id": "reaction_10038380", "reactome": "R-BTA-159567", "name": "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_159559" ], "products": [ "species_159448", "species_159450", "species_159557" ], "modifiers": [ [ "species_10038377", "catalyst" ] ], "additional_components": [ "A7MBE6", "ENSBTAT00000025874" ] }, "reaction_10038382": { "compartment": "compartment_5460", "id": "reaction_10038382", "reactome": "R-BTA-159574", "name": "salicylate-CoA + glycine => salicyluric acid + Coenzyme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_159557" ], "products": [ "species_29374", "species_159572" ], "modifiers": [ [ "species_10038368", "catalyst" ] ], "additional_components": [ "A0A3Q1MBJ0", "ENSBTAT00000077055" ] }, "reaction_10083864": { "compartment": "compartment_984", "id": "reaction_10083864", "reactome": "R-BTA-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870906" ], "products": [ "species_109277", "species_8870962" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083852": { "compartment": "compartment_984", "id": "reaction_10083852", "reactome": "R-BTA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936166", "species_109276" ], "products": [ "species_109277", "species_8851092" ], "modifiers": [ [ "species_10083849", "catalyst" ] ], "additional_components": [ "CHEBI:16039", "species_29438", "species_29494", "species_110614", "species_113592", "species_2509811", "species_29370", "species_205687", "species_29420", "species_110094", "species_29926", "species_74016", "G3MZH7", "ENSBTAT00000063714" ] }, "reaction_10083873": { "compartment": "compartment_17963", "id": "reaction_10083873", "reactome": "R-BTA-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851226", "species_8851227" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110094", "species_205687", "species_29420", "CHEBI:18075", "species_113578", "species_109366", "species_109402", "species_727810", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083889": { "compartment": "compartment_984", "id": "reaction_10083889", "reactome": "R-BTA-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8851462" ], "products": [ "species_109277", "species_8851461" ], "modifiers": [ [ "species_10083886", "catalyst" ] ], "additional_components": [ "species_2509811", "species_205687", "species_29420", "species_110094", "species_109402", "species_2509792", "species_727810", "species_113578", "Q2KJI4", "ENSBTAT00000081265", "species_29926", "species_74016" ] }, "reaction_10083861": { "compartment": "compartment_984", "id": "reaction_10083861", "reactome": "R-BTA-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277" ], "modifiers": [ [ "species_10083858", "catalyst" ] ], "additional_components": [ "species_29926", "species_74016", "A0A3Q1LNT1", "ENSBTAT00000085096" ] }, "reaction_10083876": { "compartment": "compartment_17963", "id": "reaction_10083876", "reactome": "R-BTA-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2022884", "species_8851233" ], "products": [ "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10083870", "catalyst" ] ], "additional_components": [ "species_110614", "species_29494", "species_29438", "species_30187", "species_110094", "species_205687", "species_29420", "CHEBI:18075", "A0A3Q1M496", "ENSBTAT00000071190", "species_74016" ] }, "reaction_10083926": { "compartment": "compartment_528865", "id": "reaction_10083926", "reactome": "R-BTA-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851517", "species_8851509" ], "products": [ "species_8851513", "species_8851518" ], "modifiers": [ [ "species_10083923", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_110094", "species_205687", "species_29420", "species_74016", "G3MYV7", "ENSBTAT00000062934" ] }, "reaction_10066684": { "compartment": "compartment_7660", "id": "reaction_10066684", "reactome": "R-BTA-3215310", "name": "USP7 deubiquitinates TP53 and counteracts MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10066675" ], "products": [ "species_10066677", "species_10036828" ], "modifiers": [ [ "species_10066681", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000007177" ] }, "reaction_10081541": { "compartment": "compartment_7660", "id": "reaction_10081541", "reactome": "R-BTA-6804441", "name": "RNF34 or RFFL ubiquitinates phosphorylated TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10036828" ], "products": [ "species_10081534" ], "modifiers": [ [ "species_10081538", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "P67939", "ENSBTAT00000001420", "ENSBTAT00000083405" ] }, "reaction_10066737": { "compartment": "compartment_7660", "id": "reaction_10066737", "reactome": "R-BTA-3222116", "name": "L3MBTL1 binds TP53 monomethylated on K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066733", "species_10066728" ], "products": [ "species_10066735" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000069634", "A0A3Q1M5Y5", "ENSBTAT00000069634", "P67939", "ENSBTAT00000001420" ] }, "reaction_10081877": { "compartment": "compartment_7660", "id": "reaction_10081877", "reactome": "R-BTA-6805730", "name": "SETD9 methylates TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10033524" ], "products": [ "species_77502", "species_10081870" ], "modifiers": [ [ "species_10081874", "catalyst" ] ], "additional_components": [ "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "ENSBTAT00000052840" ] }, "reaction_10066724": { "compartment": "compartment_7660", "id": "reaction_10066724", "reactome": "R-BTA-3222093", "name": "BRD7 binds TP53 and EP300", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10066720", "species_10053052" ], "products": [ "species_10066722" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000067101", "ENSBTAT00000021556", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10072550": { "compartment": "compartment_7660", "id": "reaction_10072550", "reactome": "R-BTA-5628871", "name": "BRD7 promotes EP300-mediated acetylation of TP53", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066722", "species_113560" ], "products": [ "species_2485002", "species_10072547" ], "modifiers": [ [ "species_10066722", "catalyst" ] ], "additional_components": [ "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420", "E1B8D6", "ENSBTAT00000021556", "P67939", "ENSBTAT00000001420", "A6QLF6", "ENSBTAT00000067101", "E1B8D6", "ENSBTAT00000021556", "A6QLF6", "ENSBTAT00000067101", "P67939", "ENSBTAT00000001420" ] }, "reaction_10080811": { "compartment": "compartment_7660", "id": "reaction_10080811", "reactome": "R-BTA-6799777", "name": "TP53 family members bind PPP1R13B or TP53BP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10080807", "species_10078666" ], "products": [ "species_10080809" ], "modifiers": [], "additional_components": [ "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "A0A3Q1LWL2", "ENSBTAT00000083195", "A0A3Q1NE67", "ENSBTAT00000082457" ] }, "reaction_10081530": { "compartment": "compartment_7660", "id": "reaction_10081530", "reactome": "R-BTA-6804425", "name": "TP53 binds POU4F2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081526", "species_10033524" ], "products": [ "species_10081528" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007421", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BLU8", "ENSBTAT00000007421" ] }, "reaction_10080797": { "compartment": "compartment_7660", "id": "reaction_10080797", "reactome": "R-BTA-6799761", "name": "TP53 binds PPP1R13L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078666", "species_10080793" ], "products": [ "species_10080795" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420", "ENSBTAT00000070207", "A0A3Q1M2S9", "ENSBTAT00000070207", "G3X6J7", "ENSBTAT00000007643", "P67939", "ENSBTAT00000001420" ] }, "reaction_10066764": { "compartment": "compartment_7660", "id": "reaction_10066764", "reactome": "R-BTA-3222259", "name": "PHF20 binds TP53 dimethylated on K370 and K382", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066754", "species_10066760" ], "products": [ "species_10066762" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "P67939", "ENSBTAT00000001420", "P67939", "ENSBTAT00000001420", "E1BMS9", "ENSBTAT00000007321" ] }, "reaction_10081889": { "compartment": "compartment_7660", "id": "reaction_10081889", "reactome": "R-BTA-6805792", "name": "p-S291-PHF20 translocates to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10081885" ], "products": [ "species_10081887" ], "modifiers": [], "additional_components": [ "ENSBTAT00000007321", "ENSBTAT00000007321" ] }, "reaction_10081522": { "compartment": "compartment_7660", "id": "reaction_10081522", "reactome": "R-BTA-6804402", "name": "TP53 binds POU4F1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10033524", "species_10081518" ], "products": [ "species_10081520" ], "modifiers": [], "additional_components": [ "P67939", "ENSBTAT00000001420", "ENSBTAT00000077824", "A0A3Q1MTW2", "ENSBTAT00000077824", "P67939", "ENSBTAT00000001420" ] }, "reaction_10078474": { "compartment": "compartment_7660", "id": "reaction_10078474", "reactome": "R-BTA-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10078470", "species_10037102" ], "products": [ "species_10078472" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002003", "ENSBTAT00000063128", "G3N172", "ENSBTAT00000063128", "E1BB52", "ENSBTAT00000002003" ] }, "reaction_10072571": { "compartment": "compartment_70101", "id": "reaction_10072571", "reactome": "R-BTA-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072563", "species_29408" ], "products": [ "species_29356", "species_10072568" ], "modifiers": [ [ "species_10072563", "catalyst" ] ], "additional_components": [ "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751" ] }, "reaction_10072557": { "compartment": "compartment_70101", "id": "reaction_10072557", "reactome": "R-BTA-5628905", "name": "TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_30533" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10072554", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022146" ] }, "reaction_10072591": { "compartment": "compartment_70101", "id": "reaction_10072591", "reactome": "R-BTA-5631903", "name": "SESN1,2,3 bind overoxidized PRDX1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072587", "species_10072568" ], "products": [ "species_10072589" ], "modifiers": [], "additional_components": [ "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q5E947", "ENSBTAT00000004751", "Q5E947", "ENSBTAT00000004751", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532" ] }, "reaction_10072595": { "compartment": "compartment_70101", "id": "reaction_10072595", "reactome": "R-BTA-5631941", "name": "SESN1,2,3 bind AMPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10046570", "species_10072587" ], "products": [ "species_10072593" ], "modifiers": [], "additional_components": [ "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "Q58CN8", "ENSBTAT00000042886", "A7MBI2", "ENSBTAT00000034532", "species_76577", "F1MQV7", "ENSBTAT00000024965", "F1MBG5", "ENSBTAT00000000017", "Q5BIS9", "ENSBTAT00000007798", "E1B986", "ENSBTAT00000080624", "A0A3Q1MSS5", "ENSBTAT00000086099" ] }, "reaction_10072614": { "compartment": "compartment_70101", "id": "reaction_10072614", "reactome": "R-BTA-5632738", "name": "DDIT4 binds 14-3-3 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037670", "species_10072610" ], "products": [ "species_10072612" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000000187", "Q08E62", "ENSBTAT00000000187", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10053210": { "compartment": "compartment_876", "id": "reaction_10053210", "reactome": "R-BTA-937311", "name": "ATP4A/12A:ATP4B exchanges K+ for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74126", "species_29356", "species_70106", "species_113592" ], "products": [ "species_351626", "species_29804", "species_29372", "species_29370" ], "modifiers": [ [ "species_10053207", "catalyst" ] ], "additional_components": [ "F1MXW4", "ENSBTAT00000011569", "A0A3Q1M1C8", "ENSBTAT00000073742", "E1BLX8", "ENSBTAT00000026587" ] }, "reaction_10053258": { "compartment": "compartment_876", "id": "reaction_10053258", "reactome": "R-BTA-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_947594" ], "products": [ "species_29372", "species_29370", "species_947588" ], "modifiers": [ [ "species_10053255", "catalyst" ] ], "additional_components": [ "species_1602375", "species_1500646", "species_1500646", "species_1602375", "F1MZ89", "ENSBTAT00000035192", "A0A3Q1MCF3", "ENSBTAT00000082277", "A0A3Q1M082", "ENSBTAT00000075591", "F1N3G6", "ENSBTAT00000021914" ] }, "reaction_10076172": { "compartment": "compartment_70101", "id": "reaction_10076172", "reactome": "R-BTA-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29418", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1981162" ], "modifiers": [ [ "species_10076169", "catalyst" ] ], "additional_components": [ "ENSBTAT00000009383" ] }, "reaction_10076179": { "compartment": "compartment_70101", "id": "reaction_10076179", "reactome": "R-BTA-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5692450" ], "products": [ "species_29372", "species_29370", "species_5692484" ], "modifiers": [ [ "species_10076176", "catalyst" ] ], "additional_components": [ "ENSBTAT00000010946" ] }, "reaction_10053143": { "compartment": "compartment_20699", "id": "reaction_10053143", "reactome": "R-BTA-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_74016" ], "products": [ "species_29372", "species_29370", "species_167012" ], "modifiers": [ [ "species_10053140", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1LYD6", "ENSBTAT00000086525" ] }, "reaction_10071254": { "compartment": "compartment_70101", "id": "reaction_10071254", "reactome": "R-BTA-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5252122", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5252016" ], "modifiers": [ [ "species_10071251", "catalyst" ] ], "additional_components": [ "F1N272", "ENSBTAT00000021694", "A0A3Q1M0A4", "ENSBTAT00000077002" ] }, "reaction_10057787": { "compartment": "compartment_5460", "id": "reaction_10057787", "reactome": "R-BTA-1362408", "name": "FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379721", "species_10057762", "species_10057776" ], "products": [ "species_10057778", "species_379697", "species_10057784" ], "modifiers": [ [ "species_10057762", "catalyst" ], [ "species_10057776", "catalyst" ] ], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "CHEBI:33739", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33737", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "CHEBI:33738", "P00257", "ENSBTAT00000015660", "Q05B51", "ENSBTAT00000013630" ] }, "reaction_10057792": { "compartment": "compartment_5460", "id": "reaction_10057792", "reactome": "R-BTA-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113531", "species_10057790" ], "products": [ "species_10057762" ], "modifiers": [], "additional_components": [ "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648", "Q0VCG0", "ENSBTAT00000044551", "Q05B87", "ENSBTAT00000001725", "species_71067", "A5PKG4", "ENSBTAT00000009149", "Q17QE6", "ENSBTAT00000015648" ] }, "reaction_10086272": { "compartment": "compartment_5460", "id": "reaction_10086272", "reactome": "R-BTA-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086254", "species_10086264" ], "products": [ "species_10086252", "species_10086266" ], "modifiers": [ [ "species_10086270", "catalyst" ] ], "additional_components": [ "A6QLZ6", "ENSBTAT00000017860", "CHEBI:33739", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "ENSBTAT00000017860", "Q3SZG8", "ENSBTAT00000079550", "Q2TBG7", "ENSBTAT00000029272", "CHEBI:49883", "ENSBTAT00000044111" ] }, "reaction_10070682": { "compartment": "compartment_70101", "id": "reaction_10070682", "reactome": "R-BTA-5218891", "name": "RIPK1:RIPK3 oligomer binds MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070678", "species_10067320" ], "products": [ "species_10070680" ], "modifiers": [], "additional_components": [ "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10072346": { "compartment": "compartment_876", "id": "reaction_10072346", "reactome": "R-BTA-5620975", "name": "MLKL binds PIPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067330", "species_5620974" ], "products": [ "species_10072328" ], "modifiers": [ [ "species_10072344", "inhibitor" ], [ "species_10072338", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "species_179838", "species_1806180", "species_6810412", "species_179838", "species_1806180", "species_6810412", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "F6QH17", "ENSBTAT00000026526", "E1BKM4", "ENSBTAT00000023165", "Q08DN8", "ENSBTAT00000013135", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070684": { "compartment": "compartment_70101", "id": "reaction_10070684", "reactome": "R-BTA-5218905", "name": "RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067318" ], "products": [ "species_10067320" ], "modifiers": [], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070689": { "compartment": "compartment_70101", "id": "reaction_10070689", "reactome": "R-BTA-5218906", "name": "RIPK3 phosphorylates MLKL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070680" ], "products": [ "species_29370", "species_10070686" ], "modifiers": [ [ "species_10070680", "catalyst" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BGC6", "ENSBTAT00000082389" ] }, "reaction_10070531": { "compartment": "compartment_70101", "id": "reaction_10070531", "reactome": "R-BTA-5213464", "name": "RIPK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070524" ], "products": [ "species_29370", "species_10070526" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10070534": { "compartment": "compartment_70101", "id": "reaction_10070534", "reactome": "R-BTA-5213466", "name": "RIPK3 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10070526" ], "products": [ "species_10067318", "species_29370" ], "modifiers": [ [ "species_10070524", "catalyst" ], [ "species_10070529", "inhibitor" ] ], "additional_components": [ "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511", "Q3SZK6", "ENSBTAT00000008367", "E1BKA8", "ENSBTAT00000024511" ] }, "reaction_10061064": { "compartment": "compartment_70101", "id": "reaction_10061064", "reactome": "R-BTA-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629731" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061067": { "compartment": "compartment_70101", "id": "reaction_10061067", "reactome": "R-BTA-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629753" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10060986": { "compartment": "compartment_70101", "id": "reaction_10060986", "reactome": "R-BTA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_114520" ], "products": [ "species_29372", "species_1629739" ], "modifiers": [ [ "species_10060509", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022635" ] }, "reaction_10060938": { "compartment": "compartment_70101", "id": "reaction_10060938", "reactome": "R-BTA-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_870330" ], "products": [ "species_29372", "species_426910" ], "modifiers": [ [ "species_10060935", "catalyst" ] ], "additional_components": [ "P20456", "ENSBTAT00000015548", "species_29926", "A0A3Q1LZI8", "ENSBTAT00000077982" ] }, "reaction_10061134": { "compartment": "compartment_70101", "id": "reaction_10061134", "reactome": "R-BTA-1855232", "name": "I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629746" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061061": { "compartment": "compartment_70101", "id": "reaction_10061061", "reactome": "R-BTA-1855208", "name": "I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629739" ], "products": [ "species_29372", "species_1629753" ], "modifiers": [ [ "species_10061058", "catalyst" ] ], "additional_components": [ "species_29926", "P21327", "ENSBTAT00000084681" ] }, "reaction_10061014": { "compartment": "compartment_70101", "id": "reaction_10061014", "reactome": "R-BTA-1855180", "name": "I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994123" ], "products": [ "species_29372", "species_1629769" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10061046": { "compartment": "compartment_70101", "id": "reaction_10061046", "reactome": "R-BTA-1855202", "name": "I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1629746" ], "products": [ "species_29372", "species_1629731" ], "modifiers": [ [ "species_10060585", "catalyst" ] ], "additional_components": [ "ENSBTAT00000079052" ] }, "reaction_10044666": { "compartment": "compartment_876", "id": "reaction_10044666", "reactome": "R-BTA-266082", "name": "ABCG1-mediated transport of intracellular cholesterol to the cell surface", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_216762", "species_113592" ], "products": [ "species_29372", "species_29370", "species_171095" ], "modifiers": [ [ "species_10044663", "catalyst" ] ], "additional_components": [ "A0A3Q1M833", "ENSBTAT00000085091" ] }, "reaction_10074493": { "compartment": "compartment_70101", "id": "reaction_10074493", "reactome": "R-BTA-5682285", "name": "ABCA12 transports lipids from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5682283", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_5229279" ], "modifiers": [ [ "species_10074490", "catalyst" ] ], "additional_components": [ "ENSBTAT00000004518" ] }, "reaction_10046707": { "compartment": "compartment_17947", "id": "reaction_10046707", "reactome": "R-BTA-382575", "name": "ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_382577" ], "products": [ "species_382571", "species_29372", "species_29370" ], "modifiers": [ [ "species_10046704", "catalyst" ] ], "additional_components": [ "Q2KJ57", "ENSBTAT00000027382" ] }, "reaction_10058216": { "compartment": "compartment_70101", "id": "reaction_10058216", "reactome": "R-BTA-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1454930" ], "products": [ "species_29372", "species_29370", "species_1454919" ], "modifiers": [ [ "species_10058213", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ85", "ENSBTAT00000076899", "E1BNL1", "ENSBTAT00000007685", "F1N4I6", "ENSBTAT00000014417", "F1N3Y6", "ENSBTAT00000026744", "F1MUC1", "ENSBTAT00000013298" ] }, "reaction_10074360": { "compartment": "compartment_984", "id": "reaction_10074360", "reactome": "R-BTA-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429802", "species_113592" ], "products": [ "species_382539", "species_29372", "species_29370" ], "modifiers": [ [ "species_10074357", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070307" ] }, "reaction_10070728": { "compartment": "compartment_70101", "id": "reaction_10070728", "reactome": "R-BTA-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_5223341" ], "products": [ "species_5223344", "species_29372", "species_29370" ], "modifiers": [ [ "species_10070725", "catalyst" ] ], "additional_components": [ "A0A3Q1LZ87", "ENSBTAT00000070992" ] }, "reaction_10057832": { "compartment": "compartment_17906", "id": "reaction_10057832", "reactome": "R-BTA-1369065", "name": "ABCB6 transports porphyrin from cytosol to mitchondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1369066", "species_29356", "species_113592" ], "products": [ "species_29372", "species_29370", "species_1369027" ], "modifiers": [ [ "species_10057829", "catalyst" ] ], "additional_components": [ "A5D7P7", "ENSBTAT00000027459" ] }, "reaction_10046698": { "compartment": "compartment_70616", "id": "reaction_10046698", "reactome": "R-BTA-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_189444", "species_113521" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10046695", "catalyst" ] ], "additional_components": [ "A0A3Q1MUB7", "ENSBTAT00000085390" ] }, "reaction_10058469": { "compartment": "compartment_876", "id": "reaction_10058469", "reactome": "R-BTA-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_1131652" ], "products": [ "species_29372", "species_29370", "species_1467459" ], "modifiers": [ [ "species_10058466", "catalyst" ] ], "additional_components": [ "A0A3Q1MB23", "ENSBTAT00000080713", "A0A3Q1LS24", "ENSBTAT00000073046" ] }, "reaction_10070743": { "compartment": "compartment_70101", "id": "reaction_10070743", "reactome": "R-BTA-5227009", "name": "ABCF1 binds EIF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10070739", "species_10034379" ], "products": [ "species_10070741" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070886", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "Q2KHU8", "ENSBTAT00000019064", "P68102", "ENSBTAT00000071779", "A0A3Q1LQI5", "ENSBTAT00000086329", "A0A3Q1NB13", "ENSBTAT00000070886" ] }, "reaction_10088584": { "compartment": "compartment_7660", "id": "reaction_10088584", "reactome": "R-BTA-8954056", "name": "E2F6 binds TFDP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056555" ], "products": [ "species_10088582" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000076561", "A0A3Q1MKK9", "ENSBTAT00000076561", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088554": { "compartment": "compartment_7660", "id": "reaction_10088554", "reactome": "R-BTA-8953111", "name": "E2F6 binds TFDP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10056551" ], "products": [ "species_10088552" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000084839", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10089578": { "compartment": "compartment_7660", "id": "reaction_10089578", "reactome": "R-BTA-9007447", "name": "E2F6 forms the PRC1L4 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088550", "species_10089554", "species_10089550", "species_10066826", "species_10081545" ], "products": [ "species_10089576" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028703", "ENSBTAT00000013026", "ENSBTAT00000076903", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "ENSBTAT00000085264", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "A6H7C4", "ENSBTAT00000076903", "E1BJL2", "ENSBTAT00000013026", "Q08DY6", "ENSBTAT00000028703" ] }, "reaction_10088564": { "compartment": "compartment_7660", "id": "reaction_10088564", "reactome": "R-BTA-8953115", "name": "E2F6:TFDP1 binds to MGA:MAX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088560", "species_10088552" ], "products": [ "species_10088562" ], "modifiers": [], "additional_components": [ "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10088596": { "compartment": "compartment_7660", "id": "reaction_10088596", "reactome": "R-BTA-8954082", "name": "E2F6 binds the PRC1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088592", "species_10088586" ], "products": [ "species_10088594" ], "modifiers": [], "additional_components": [ "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BMR4", "ENSBTAT00000077318", "Q32KX7", "ENSBTAT00000073960", "A0A3Q1MBA7", "ENSBTAT00000073548", "A0A3Q1LF83", "ENSBTAT00000077335", "A0A3Q1LR89", "ENSBTAT00000086711" ] }, "reaction_10089574": { "compartment": "compartment_7660", "id": "reaction_10089574", "reactome": "R-BTA-9007283", "name": "CBX3 and PRC1.6 associate with E2F6.com-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10089570", "species_10089550", "species_10089560" ], "products": [ "species_10089572" ], "modifiers": [], "additional_components": [ "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877", "ENSBTAT00000076903", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A0A3Q1MS74", "ENSBTAT00000085264", "A6QLQ0", "ENSBTAT00000000025", "A0A3Q1LR89", "ENSBTAT00000086711", "E1BJL2", "ENSBTAT00000013026", "Q0VC56", "ENSBTAT00000064422", "A6H7C4", "ENSBTAT00000076903", "F1N093", "ENSBTAT00000016118", "Q17QZ4", "ENSBTAT00000084839", "Q08DY6", "ENSBTAT00000028703", "E1BKB7", "ENSBTAT00000020143", "A0A3Q1MV00", "ENSBTAT00000069877" ] }, "reaction_10091049": { "compartment": "compartment_7660", "id": "reaction_10091049", "reactome": "R-BTA-9617927", "name": "FOXO4 binds ATXN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042669", "species_10075370" ], "products": [ "species_10091047" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "ENSBTAT00000007611", "A6H799", "ENSBTAT00000007611", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091096": { "compartment": "compartment_7660", "id": "reaction_10091096", "reactome": "R-BTA-9620532", "name": "SIRT1,SIRT3 deacetylate FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427523", "species_10091084" ], "products": [ "species_427497", "species_427498", "species_10042665" ], "modifiers": [ [ "species_10091093", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "G5E521", "ENSBTAT00000002648", "F1MQB8", "ENSBTAT00000018630" ] }, "reaction_10091089": { "compartment": "compartment_7660", "id": "reaction_10091089", "reactome": "R-BTA-9620515", "name": "KAT2B,EP300 acetylate FOXO3 under oxidative stress", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113560", "species_10042665" ], "products": [ "species_2485002", "species_10091084" ], "modifiers": [ [ "species_10091086", "catalyst" ], [ "species_3785707", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014920", "ENSBTAT00000014920", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10091184": { "compartment": "compartment_7660", "id": "reaction_10091184", "reactome": "R-BTA-9626928", "name": "CREBBP binds FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10042661" ], "products": [ "species_10091182" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10091017": { "compartment": "compartment_7660", "id": "reaction_10091017", "reactome": "R-BTA-9614414", "name": "AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10042696" ], "products": [ "species_10091015" ], "modifiers": [], "additional_components": [ "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418", "A0A452DJI7", "ENSBTAT00000061127", "F1N4K5", "ENSBTAT00000014920", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091033": { "compartment": "compartment_70101", "id": "reaction_10091033", "reactome": "R-BTA-9614564", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091013", "species_10037662" ], "products": [ "species_10091031" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006418", "P63103", "ENSBTAT00000000289", "P63103", "ENSBTAT00000000289", "A6QLP0", "ENSBTAT00000006418" ] }, "reaction_10091023": { "compartment": "compartment_70101", "id": "reaction_10091023", "reactome": "R-BTA-9614423", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091019", "species_10044088" ], "products": [ "species_10091021" ], "modifiers": [], "additional_components": [ "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411", "ENSBTAT00000061127", "A0A452DJI7", "ENSBTAT00000061127", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10091029": { "compartment": "compartment_70101", "id": "reaction_10091029", "reactome": "R-BTA-9614562", "name": "14-3-3 proteins bind AKT-phosphorylated FOXO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091011", "species_10091025" ], "products": [ "species_10091027" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014920", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "A0A3Q1M2Q2", "ENSBTAP00000064310", "P63103", "ENSBTAT00000000289", "Q0VC36", "ENSBTAT00000012154", "F1N4K5", "ENSBTAT00000014920" ] }, "reaction_10088872": { "compartment": "compartment_7660", "id": "reaction_10088872", "reactome": "R-BTA-8956659", "name": "ABL1 phosphorylates YAP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10057280" ], "products": [ "species_113582", "species_10088870" ], "modifiers": [ [ "species_10075170", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000006112", "ENSBTAT00000080797" ] }, "reaction_10088876": { "compartment": "compartment_7660", "id": "reaction_10088876", "reactome": "R-BTA-8956676", "name": "YAP1 binds TP73", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088870", "species_10078664" ], "products": [ "species_10088874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10088887": { "compartment": "compartment_13231", "id": "reaction_10088887", "reactome": "R-BTA-8957241", "name": "TP73 tetramer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10088880" ], "products": [ "species_10078664" ], "modifiers": [], "additional_components": [ "G3X6J7", "ENSBTAT00000007643", "G3X6J7", "ENSBTAT00000007643" ] }, "reaction_10086458": { "compartment": "compartment_7660", "id": "reaction_10086458", "reactome": "R-BTA-8936481", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086449" ], "products": [ "species_77502", "species_10086455" ], "modifiers": [ [ "species_10086449", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086493": { "compartment": "compartment_7660", "id": "reaction_10086493", "reactome": "R-BTA-8936584", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086477" ], "products": [ "species_77502", "species_10086490" ], "modifiers": [ [ "species_10086477", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086509": { "compartment": "compartment_7660", "id": "reaction_10086509", "reactome": "R-BTA-8936621", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086504" ], "products": [ "species_77502", "species_10086506" ], "modifiers": [ [ "species_10086504", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086525": { "compartment": "compartment_7660", "id": "reaction_10086525", "reactome": "R-BTA-8937022", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086520" ], "products": [ "species_77502", "species_10086522" ], "modifiers": [ [ "species_10086520", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086541": { "compartment": "compartment_7660", "id": "reaction_10086541", "reactome": "R-BTA-8937113", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086536" ], "products": [ "species_77502", "species_10086538" ], "modifiers": [ [ "species_10086536", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086502": { "compartment": "compartment_7660", "id": "reaction_10086502", "reactome": "R-BTA-8936608", "name": "PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086497" ], "products": [ "species_77502", "species_10086499" ], "modifiers": [ [ "species_10086497", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1MTR3", "ENSBTAT00000013167", "E1B9S8", "ENSBTAT00000021434", "Q5E9L5", "ENSBTAT00000009750" ] }, "reaction_10086518": { "compartment": "compartment_7660", "id": "reaction_10086518", "reactome": "R-BTA-8937016", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086513" ], "products": [ "species_77502", "species_10086515" ], "modifiers": [ [ "species_10086513", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086534": { "compartment": "compartment_7660", "id": "reaction_10086534", "reactome": "R-BTA-8937050", "name": "Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10086529" ], "products": [ "species_77502", "species_10086531" ], "modifiers": [ [ "species_10086529", "catalyst" ] ], "additional_components": [ "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "Q5E9F8", "ENSBTAT00000034695", "P84227", "ENSBTAT00000079615", "P68432", "ENSBTAT00000087179", "F1N6T0", "ENSBTAT00000047968", "E1BI59", "ENSBTAT00000004135", "E1BEP4", "ENSBTAT00000001294", "Q2NKU6", "ENSBTAT00000012183", "A4FUE3", "ENSBTAT00000021204", "E1BLX2", "ENSBTAT00000070677", "F1MHA1", "ENSBTAT00000024084", "A0A3Q1N7T9", "ENSBTAT00000083957", "E1B8D6", "ENSBTAT00000021556", "A0A3Q1MLT2", "ENSBTAT00000075969" ] }, "reaction_10086638": { "compartment": "compartment_161320", "id": "reaction_10086638", "reactome": "R-BTA-8938108", "name": "SERPINB13 binds cathepsin L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086634", "species_10063945" ], "products": [ "species_10086636" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005068", "ENSBTAT00000036427", "A0A452DK38", "ENSBTAT00000036427", "E1BIP8", "ENSBTAT00000005068" ] }, "reaction_10084922": { "compartment": "compartment_7660", "id": "reaction_10084922", "reactome": "R-BTA-8864595", "name": "TFAP2B homodimer binds YEATS4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084918", "species_10084916" ], "products": [ "species_10084920" ], "modifiers": [], "additional_components": [ "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000002913", "Q32LE1", "ENSBTAT00000002913", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084911": { "compartment": "compartment_70101", "id": "reaction_10084911", "reactome": "R-BTA-8864577", "name": "TFAP2C translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084905" ], "products": [ "species_10066845" ], "modifiers": [ [ "species_10084907", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000002671", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084895": { "compartment": "compartment_7660", "id": "reaction_10084895", "reactome": "R-BTA-8864307", "name": "TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044438", "species_10084879", "species_10053052", "species_10084891" ], "products": [ "species_10084893" ], "modifiers": [], "additional_components": [ "ENSBTAT00000005092", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "ENSBTAT00000021556", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "Q2HJ78", "ENSBTAT00000020109", "Q0VCT9", "ENSBTAT00000014907", "E1B8D6", "ENSBTAT00000021556", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "F1MD32", "ENSBTAT00000005092" ] }, "reaction_10084881": { "compartment": "compartment_7660", "id": "reaction_10084881", "reactome": "R-BTA-8864278", "name": "AP-2 (TFAP2) transcription factors form homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084877" ], "products": [ "species_10084879" ], "modifiers": [], "additional_components": [ "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276" ] }, "reaction_10084935": { "compartment": "compartment_7660", "id": "reaction_10084935", "reactome": "R-BTA-8865265", "name": "TFAP2C homodimer binds MYC and KDM5B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069764", "species_10077310", "species_10066847" ], "products": [ "species_10084933" ], "modifiers": [], "additional_components": [ "ENSBTAT00000028871", "ENSBTAT00000076263", "Q0VC14", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "Q2HJ27", "ENSBTAT00000076263", "F1MUR2", "ENSBTAT00000028871" ] }, "reaction_10084909": { "compartment": "compartment_70101", "id": "reaction_10084909", "reactome": "R-BTA-8864569", "name": "WWOX binds TFAP2C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057268", "species_10084905" ], "products": [ "species_10084907" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086215", "ENSBTAT00000002671", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1LVN4", "ENSBTAT00000086215" ] }, "reaction_10084903": { "compartment": "compartment_7660", "id": "reaction_10084903", "reactome": "R-BTA-8864343", "name": "KCTD1 binds TFAP2 homo- and heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084899", "species_10084879" ], "products": [ "species_10084901" ], "modifiers": [], "additional_components": [ "ENSBTAT00000068462", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "Q0VC14", "ENSBTAT00000002671", "A0A3Q1M7U2", "ENSBTAT00000072276", "A0A3Q1MKM9", "ENSBTAT00000068462" ] }, "reaction_10063400": { "compartment": "compartment_7660", "id": "reaction_10063400", "reactome": "R-BTA-2032781", "name": "WWTR1 (TAZ) binds TEAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063396", "species_10063378" ], "products": [ "species_10063398" ], "modifiers": [], "additional_components": [ "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335", "ENSBTAT00000084991", "A0A3Q1NBB6", "ENSBTAT00000084991", "A0A3Q1N1G2", "ENSBTAT00000067627", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10063390": { "compartment": "compartment_7660", "id": "reaction_10063390", "reactome": "R-BTA-2032775", "name": "YAP1 binds TEAD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057280", "species_10063386" ], "products": [ "species_10063388" ], "modifiers": [], "additional_components": [ "ENSBTAT00000006112", "ENSBTAT00000067627", "A0A3Q1N1G2", "ENSBTAT00000067627", "F1MK73", "ENSBTAT00000006112" ] }, "reaction_10085761": { "compartment": "compartment_7660", "id": "reaction_10085761", "reactome": "R-BTA-8871265", "name": "YAP1 binds TEAD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063394", "species_10057280" ], "products": [ "species_10085759" ], "modifiers": [], "additional_components": [ "ENSBTAT00000074335", "ENSBTAT00000006112", "F1MK73", "ENSBTAT00000006112", "A0A3Q1M163", "ENSBTAT00000074335" ] }, "reaction_10046681": { "compartment": "compartment_7660", "id": "reaction_10046681", "reactome": "R-BTA-382096", "name": "Formation of NR-NCOR Corepressor Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044694", "species_10045690" ], "products": [ "species_10046679" ], "modifiers": [], "additional_components": [ "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "A0A3Q1MM20", "ENSBTAT00000072859", "A0A3Q1M5G9", "ENSBTAT00000069224", "Q5EA13", "ENSBTAT00000068423", "F1MXG9", "ENSBTAT00000052227", "A0A3Q1M9Y9", "ENSBTAT00000073553", "F1ML62", "ENSBTAT00000018926", "A0A3Q1LKK0", "ENSBTAT00000068928", "A0A3Q1N5N2", "ENSBTAT00000070997", "Q7YRQ5", "ENSBTAT00000016078", "Q5E9B6", "ENSBTAT00000071739", "F1MGG2", "ENSBTAT00000010892", "A0A3S5ZPB3", "ENSBTAT00000012145", "Q9XSB5", "ENSBTAT00000005899", "Q04752", "ENSBTAT00000011869", "A0A3Q1LZI4", "ENSBTAT00000074991", "G5E5I7", "ENSBTAT00000020641", "Q08E53", "ENSBTAT00000004758", "A0A3Q1N8R7", "ENSBTAT00000067712", "Q08DY5", "ENSBTAT00000024159", "G3X7C1", "ENSBTAT00000087040", "F1N3S3", "ENSBTAT00000014791", "F1MBX3", "ENSBTAT00000036417", "F1N712", "ENSBTAT00000010545", "A0A3Q1M3W3", "ENSBTAT00000068282", "F1MWI2", "ENSBTAT00000023994", "Q0VC20", "ENSBTAT00000022350", "F1MN19", "ENSBTAT00000077017", "A0A3Q1LZU3", "ENSBTAT00000077868", "G3X6X1", "ENSBTAT00000015305", "O18971", "ENSBTAT00000083374", "A2VDU4", "ENSBTAT00000026059", "E1BML7", "ENSBTAT00000019772", "A6H7I6", "ENSBTAT00000000860", "F1MN68", "ENSBTAT00000018594", "F1MGM4", "ENSBTAT00000061343", "A0A3Q1MY21", "ENSBTAT00000086068" ] }, "reaction_10054279": { "compartment": "compartment_7660", "id": "reaction_10054279", "reactome": "R-BTA-975040", "name": "KRAB-ZNF / KAP Interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053367", "species_10054275" ], "products": [ "species_10054277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008424", "Q17R08", "ENSBTAT00000080509", "Q17R08", "ENSBTAT00000080509", "E1BJG5", "ENSBTAT00000008424" ] }, "reaction_10065292": { "compartment": "compartment_876", "id": "reaction_10065292", "reactome": "R-BTA-2327738", "name": "DDR1 binds collagen type I, II, III, IV, V, XI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065286", "species_10065288" ], "products": [ "species_10065290" ], "modifiers": [], "additional_components": [ "E1BBP4", "ENSBTAT00000046062", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "E1BBP4", "ENSBTAT00000046062" ] }, "reaction_10068042": { "compartment": "compartment_70101", "id": "reaction_10068042", "reactome": "R-BTA-3465448", "name": "Caspase-8 and FLIP(L) processing at DISC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10068032" ], "products": [ "species_10068038", "species_10068040" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10068046": { "compartment": "compartment_876", "id": "reaction_10068046", "reactome": "R-BTA-3465459", "name": "FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10035386" ], "products": [ "species_10068044" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "Q2LGB8", "ENSBTAT00000075852", "A0A3Q1MLX3", "ENSBTAT00000085853", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282" ] }, "reaction_10067891": { "compartment": "compartment_876", "id": "reaction_10067891", "reactome": "R-BTA-3371359", "name": "FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10067887", "species_10037981" ], "products": [ "species_10067889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000085853", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "A0A3Q1MLX3", "ENSBTAT00000085853" ] }, "reaction_10037985": { "compartment": "compartment_876", "id": "reaction_10037985", "reactome": "R-BTA-141156", "name": "TRAIL-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037981", "species_10035384" ], "products": [ "species_10037983" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "E1BE56", "ENSBTAT00000025281", "Q645M6", "ENSBTAT00000024322", "Q2LGB8", "ENSBTAT00000075852", "ENSBTAT00000085853" ] }, "reaction_10035396": { "compartment": "compartment_876", "id": "reaction_10035396", "reactome": "R-BTA-73945", "name": "FAS-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035386", "species_10035384" ], "products": [ "species_10035390" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q645M6", "ENSBTAT00000024322", "A6H6Z6", "ENSBTAT00000046575", "A5D7R0", "ENSBTAT00000014282", "ENSBTAT00000085853" ] }, "reaction_10037991": { "compartment": "compartment_70101", "id": "reaction_10037991", "reactome": "R-BTA-141159", "name": "TNF-mediated dimerization of procaspase-8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037987", "species_10035384" ], "products": [ "species_10037989" ], "modifiers": [ [ "species_10035394", "inhibitor" ] ], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852", "Q3SZK6", "ENSBTAT00000008367", "Q2KI74", "ENSBTAT00000016776", "E1B9D9", "ENSBTAT00000013869", "Q645M6", "ENSBTAT00000024322", "ENSBTAT00000085853" ] }, "reaction_10043049": { "compartment": "compartment_70101", "id": "reaction_10043049", "reactome": "R-BTA-201637", "name": "Caspase-mediated cleavage of plectin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043043" ], "products": [ "species_10043047", "species_10043045" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000082561", "ENSBTAT00000082561", "ENSBTAT00000082561", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044762": { "compartment": "compartment_70101", "id": "reaction_10044762", "reactome": "R-BTA-350319", "name": "Caspase mediated cleavage of vimentin at IDVD (259)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044758", "species_10044760" ], "modifiers": [ [ "species_10037638", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10043021": { "compartment": "compartment_70101", "id": "reaction_10043021", "reactome": "R-BTA-201628", "name": "Caspase-mediated cleavage of vimentin at DSVD (85)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10043018", "species_10043016" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043059": { "compartment": "compartment_70101", "id": "reaction_10043059", "reactome": "R-BTA-201639", "name": "Caspase-mediated cleavage of GAS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043053" ], "products": [ "species_10043057", "species_10043055" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028855", "ENSBTAT00000028855", "ENSBTAT00000028855", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044756": { "compartment": "compartment_70101", "id": "reaction_10044756", "reactome": "R-BTA-350318", "name": "Caspase-mediated cleavage of vimentin at TNLD (429)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043014" ], "products": [ "species_10044743", "species_10044745" ], "modifiers": [ [ "species_10044753", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024572", "ENSBTAT00000024572", "ENSBTAT00000024572", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044923": { "compartment": "compartment_7660", "id": "reaction_10044923", "reactome": "R-BTA-351936", "name": "Caspase-mediated cleavage of claspin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10040063" ], "products": [ "species_10044912", "species_10044910" ], "modifiers": [ [ "species_10044920", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074281", "ENSBTAT00000074281", "ENSBTAT00000074281", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044906": { "compartment": "compartment_70101", "id": "reaction_10044906", "reactome": "R-BTA-351901", "name": "Caspase-mediated cleavage of MST3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044900" ], "products": [ "species_10044902", "species_10044904" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747", "ENSBTAT00000075747", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10090573": { "compartment": "compartment_7660", "id": "reaction_10090573", "reactome": "R-BTA-9029680", "name": "Caspase-7 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037229" ], "products": [ "species_10044920" ], "modifiers": [], "additional_components": [ "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10043039": { "compartment": "compartment_70101", "id": "reaction_10043039", "reactome": "R-BTA-201634", "name": "Caspase-mediated cleavage of FADK 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043033" ], "products": [ "species_10043037", "species_10043035" ], "modifiers": [ [ "species_10037229", "catalyst" ] ], "additional_components": [ "ENSBTAT00000085237", "ENSBTAT00000085237", "ENSBTAT00000085237", "F1MD58", "ENSBTAT00000008706" ] }, "reaction_10044896": { "compartment": "compartment_12045", "id": "reaction_10044896", "reactome": "R-BTA-351894", "name": "Caspase mediated cleavage of BAP31", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044887" ], "products": [ "species_10044893", "species_10044891", "species_10044889" ], "modifiers": [ [ "species_10044867", "catalyst" ] ], "additional_components": [ "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "ENSBTAT00000068015", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10044995": { "compartment": "compartment_7660", "id": "reaction_10044995", "reactome": "R-BTA-352268", "name": "Cleavage of Satb1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044989" ], "products": [ "species_10044993", "species_10044991" ], "modifiers": [ [ "species_10044565", "catalyst" ] ], "additional_components": [ "ENSBTAT00000028199", "ENSBTAT00000028199", "ENSBTAT00000028199", "G3X702", "ENSBTAT00000016642" ] }, "reaction_10044927": { "compartment": "compartment_13231", "id": "reaction_10044927", "reactome": "R-BTA-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044902" ], "products": [ "species_10044925" ], "modifiers": [], "additional_components": [ "ENSBTAT00000075747", "ENSBTAT00000075747" ] }, "reaction_10044869": { "compartment": "compartment_70101", "id": "reaction_10044869", "reactome": "R-BTA-351863", "name": "Translocation of active caspase-8 to the mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037638" ], "products": [ "species_10044867" ], "modifiers": [], "additional_components": [ "Q2LGB8", "ENSBTAT00000075852", "Q2LGB8", "ENSBTAT00000075852" ] }, "reaction_10037723": { "compartment": "compartment_70101", "id": "reaction_10037723", "reactome": "R-BTA-139918", "name": "Phosphorylation of BIM by JNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037716", "species_113592" ], "products": [ "species_10037718", "species_29370", "species_10037721" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "P61285", "ENSBTAT00000081563", "A0A3Q1NJ55", "ENSBTAT00000078264", "P61285", "ENSBTAT00000081563", "ENSBTAT00000078264", "ENSBTAT00000087439" ] }, "reaction_10037727": { "compartment": "compartment_70101", "id": "reaction_10037727", "reactome": "R-BTA-139919", "name": "Translocation of BIM to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037721" ], "products": [ "species_10037725" ], "modifiers": [], "additional_components": [ "ENSBTAT00000078264", "ENSBTAT00000078264" ] }, "reaction_10037706": { "compartment": "compartment_70101", "id": "reaction_10037706", "reactome": "R-BTA-139909", "name": "Translocation of BMF to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037695" ], "products": [ "species_10037704" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077917", "ENSBTAT00000077917" ] }, "reaction_10037702": { "compartment": "compartment_70101", "id": "reaction_10037702", "reactome": "R-BTA-139908", "name": "Phosphorylation of DLC2 by MAPK8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10037690" ], "products": [ "species_29370", "species_10037695", "species_10037692" ], "modifiers": [ [ "species_10037699", "catalyst" ] ], "additional_components": [ "Q3MHR3", "ENSBTAT00000006190", "Q05KI3", "ENSBTAT00000077917", "ENSBTAT00000077917", "Q3MHR3", "ENSBTAT00000006190", "ENSBTAT00000087439" ] }, "reaction_10051181": { "compartment": "compartment_17906", "id": "reaction_10051181", "reactome": "R-BTA-508163", "name": "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037273", "species_10051177" ], "products": [ "species_10051179" ], "modifiers": [], "additional_components": [ "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264", "F6R2C4", "ENSBTAT00000025701", "Q05KI3", "ENSBTAT00000077917", "A0A3Q1NJ55", "ENSBTAT00000078264" ] }, "reaction_10037277": { "compartment": "compartment_17906", "id": "reaction_10037277", "reactome": "R-BTA-114352", "name": "Sequestration of tBID by BCL-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037269", "species_10037273" ], "products": [ "species_10037275" ], "modifiers": [], "additional_components": [ "ENSBTAT00000042737", "ENSBTAT00000025701", "F6R2C4", "ENSBTAT00000025701", "Q17QH5", "ENSBTAT00000042737" ] }, "reaction_10051175": { "compartment": "compartment_17906", "id": "reaction_10051175", "reactome": "R-BTA-508162", "name": "BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10051171", "species_10051167" ], "products": [ "species_10051173" ], "modifiers": [], "additional_components": [ "ENSBTAT00000076163", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "A0A3Q1NFP6", "ENSBTAT00000071269", "F1MUT9", "ENSBTAT00000016610", "A0A3Q1NJ55", "ENSBTAT00000078264", "Q17QH5", "ENSBTAT00000042737", "Q05KJ0", "ENSBTAT00000076163" ] }, "reaction_10037289": { "compartment": "compartment_70101", "id": "reaction_10037289", "reactome": "R-BTA-114354", "name": "SMAC binds XIAP:Caspase-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037283" ], "products": [ "species_10037287" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091191": { "compartment": "compartment_70101", "id": "reaction_10091191", "reactome": "R-BTA-9627350", "name": "SMAC (DIABLO) binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037285", "species_10037281" ], "products": [ "species_10037291" ], "modifiers": [], "additional_components": [ "Q2NL36", "ENSBTAT00000005496", "ENSBTAT00000067597", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10091197": { "compartment": "compartment_70101", "id": "reaction_10091197", "reactome": "R-BTA-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10091193" ], "products": [ "species_10091195" ], "modifiers": [], "additional_components": [ "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118", "G3MWG5", "ENSBTAT00000067597", "A0A3Q1MXU1", "ENSBTAT00000086118" ] }, "reaction_10091188": { "compartment": "compartment_70101", "id": "reaction_10091188", "reactome": "R-BTA-9627107", "name": "XIAP binds CASP7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037281", "species_10037229" ], "products": [ "species_10037283" ], "modifiers": [ [ "species_10037285", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000067597", "F1MD58", "ENSBTAT00000008706", "F1MD58", "ENSBTAT00000008706", "G3MWG5", "ENSBTAT00000067597", "Q2NL36", "ENSBTAT00000005496" ] }, "reaction_10039930": { "compartment": "compartment_70101", "id": "reaction_10039930", "reactome": "R-BTA-175987", "name": "NNMT transfers CH3 from AdoMet to PY", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175973", "species_71284" ], "products": [ "species_175979", "species_71285" ], "modifiers": [ [ "species_10039927", "catalyst" ] ], "additional_components": [ "ENSBTAT00000040069" ] }, "reaction_10038238": { "compartment": "compartment_70101", "id": "reaction_10038238", "reactome": "R-BTA-158609", "name": "TPMT transfers CH3 from AdoMet to 6MP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158619", "species_71284" ], "products": [ "species_70106", "species_71285", "species_158611" ], "modifiers": [ [ "species_10038235", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025698" ] }, "reaction_10076898": { "compartment": "compartment_70101", "id": "reaction_10076898", "reactome": "R-BTA-5696213", "name": "AS3MT transfers CH3 from AdoMet to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696224", "species_71284" ], "products": [ "species_5696211", "species_71285" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10071924": { "compartment": "compartment_70101", "id": "reaction_10071924", "reactome": "R-BTA-5603114", "name": "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_174390" ], "products": [ "species_111294", "species_29372", "species_71284" ], "modifiers": [ [ "species_10071921", "catalyst" ] ], "additional_components": [ "Q29RI9", "ENSBTAT00000016399", "A0A3Q1MZ37", "ENSBTAT00000075325", "species_29926", "species_74126" ] }, "reaction_10076900": { "compartment": "compartment_70101", "id": "reaction_10076900", "reactome": "R-BTA-5696220", "name": "AS3MT transfers CH3 from AdoMet to arsenite(3-)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696216", "species_71284" ], "products": [ "species_71285", "species_5696214" ], "modifiers": [ [ "species_10076895", "catalyst" ] ], "additional_components": [ "ENSBTAT00000069974" ] }, "reaction_10035863": { "compartment": "compartment_17960", "id": "reaction_10035863", "reactome": "R-BTA-76386", "name": "CYP1A2 S-demethylates 6MMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_76384", "species_113601" ], "products": [ "species_143501", "species_113519", "species_113564", "species_33153" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10076903": { "compartment": "compartment_70101", "id": "reaction_10076903", "reactome": "R-BTA-5696230", "name": "GSTO1 dimer reduces methylarsonate to methylarsonite", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5696214" ], "products": [ "species_29356", "species_5696224", "species_111745" ], "modifiers": [ [ "species_10039980", "catalyst" ] ], "additional_components": [ "E1BJ08", "ENSBTAT00000017435" ] }, "reaction_10037800": { "compartment": "compartment_984", "id": "reaction_10037800", "reactome": "R-BTA-140664", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037795", "catalyst" ], [ "species_10037798", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037852": { "compartment": "compartment_984", "id": "reaction_10037852", "reactome": "R-BTA-140700", "name": "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037763" ], "products": [ "species_10037765", "species_10037577" ], "modifiers": [ [ "species_10037785", "catalyst" ], [ "species_10037850", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000009406", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037948": { "compartment": "compartment_876", "id": "reaction_10037948", "reactome": "R-BTA-140870", "name": "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037921" ], "products": [ "species_10037945" ], "modifiers": [ [ "species_10037921", "catalyst" ] ], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037950": { "compartment": "compartment_984", "id": "reaction_10037950", "reactome": "R-BTA-140872", "name": "thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037945" ], "products": [ "species_10037829", "species_9693058" ], "modifiers": [], "additional_components": [ "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10037923": { "compartment": "compartment_984", "id": "reaction_10037923", "reactome": "R-BTA-140791", "name": "activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037919", "species_10037577" ], "products": [ "species_10037921" ], "modifiers": [], "additional_components": [ "A0A3Q1NJR8", "ENSBTAT00000071014", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10071906": { "compartment": "compartment_876", "id": "reaction_10071906", "reactome": "R-BTA-5602080", "name": "Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037841", "species_10037835" ], "products": [ "species_10037843" ], "modifiers": [], "additional_components": [ "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10090181": { "compartment": "compartment_984", "id": "reaction_10090181", "reactome": "R-BTA-9015111", "name": "Factor Xa inhibitors binds Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037785" ], "products": [ "species_10037850" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789" ] }, "reaction_10037845": { "compartment": "compartment_984", "id": "reaction_10037845", "reactome": "R-BTA-140696", "name": "factor V -> factor Va + factor V activation peptide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037817" ], "products": [ "species_10037813", "species_10037819" ], "modifiers": [ [ "species_10037577", "catalyst" ], [ "species_10037829", "inhibitor" ], [ "species_10037843", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000023573", "species_74016", "F1N0I3", "ENSBTAT00000023573", "ENSBTAT00000023573", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "A0A452DI66", "ENSBTAT00000009406", "A0A3Q1NJR8", "ENSBTAT00000071014", "A0A452DI66", "ENSBTAT00000009406", "species_74016", "CHEBI:18085", "Q8HZY1", "ENSBTAT00000011485" ] }, "reaction_10037815": { "compartment": "compartment_984", "id": "reaction_10037815", "reactome": "R-BTA-140686", "name": "factor Va + factor Xa -> Va:Xa complex (prothrombinase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037813", "species_10037807" ], "products": [ "species_10037795" ], "modifiers": [], "additional_components": [ "species_74016", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10090183": { "compartment": "compartment_984", "id": "reaction_10090183", "reactome": "R-BTA-9015122", "name": "Factor Xa inhibitors bind Va:Xa", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9038743", "species_10037795" ], "products": [ "species_10037798" ], "modifiers": [], "additional_components": [ "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573", "species_74016", "A0A452DIP8", "ENSBTAT00000021789", "F1N0I3", "ENSBTAT00000023573" ] }, "reaction_10037927": { "compartment": "compartment_984", "id": "reaction_10037927", "reactome": "R-BTA-140806", "name": "SERPINC1 binds SERPINC1 activators", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037925", "species_9693058" ], "products": [ "species_10037919" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071014", "A0A3Q1NJR8", "ENSBTAT00000071014" ] }, "reaction_10055529": { "compartment": "compartment_7660", "id": "reaction_10055529", "reactome": "R-BTA-983218", "name": "RAD51B:RAD51C binds single-stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29868", "species_10055525" ], "products": [ "species_10055527" ], "modifiers": [], "additional_components": [ "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012", "species_29868" ] }, "reaction_10055995": { "compartment": "compartment_7660", "id": "reaction_10055995", "reactome": "R-BTA-1008200", "name": "NFE2 binds the beta globin locus control region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055991", "species_1008228" ], "products": [ "species_10055993" ], "modifiers": [], "additional_components": [ "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479", "A7YY73", "ENSBTAT00000028574", "A5PJV0", "ENSBTAT00000000044", "E1BB01", "ENSBTAT00000025702", "Q5EAD3", "ENSBTAT00000066479" ] }, "reaction_10055933": { "compartment": "compartment_70101", "id": "reaction_10055933", "reactome": "R-BTA-997237", "name": "SH2B proteins bind JAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055926", "species_10055929" ], "products": [ "species_10055931" ], "modifiers": [], "additional_components": [ "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236", "ENSBTAT00000015986", "E1BCP6", "ENSBTAT00000015986", "F1MRH8", "ENSBTAT00000012781", "A0A3Q1MQG1", "ENSBTAT00000079236" ] }, "reaction_10055870": { "compartment": "compartment_7660", "id": "reaction_10055870", "reactome": "R-BTA-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055855", "species_10055866" ], "products": [ "species_10055868" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008198", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "Q5E9F8", "ENSBTAT00000034695", "P68432", "ENSBTAT00000087179", "P84227", "ENSBTAT00000079615", "F2Z4J7", "ENSBTAT00000008198" ] }, "reaction_10055649": { "compartment": "compartment_7660", "id": "reaction_10055649", "reactome": "R-BTA-983285", "name": "RAD51B binds RAD51C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055523", "species_10055519" ], "products": [ "species_10055525" ], "modifiers": [], "additional_components": [ "ENSBTAT00000020012", "ENSBTAT00000025252", "E1BE93", "ENSBTAT00000025252", "F1MW99", "ENSBTAT00000020012" ] }, "reaction_10055920": { "compartment": "compartment_7660", "id": "reaction_10055920", "reactome": "R-BTA-996755", "name": "ZFPM proteins bind GATA proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055890", "species_10055916" ], "products": [ "species_10055918" ], "modifiers": [], "additional_components": [ "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "A0A3Q1MC01", "ENSBTAT00000066877", "F1N1M2", "ENSBTAT00000007537", "A0A3Q1MGB0", "ENSBTAT00000071546", "F1N551", "ENSBTAT00000007134", "E1BI59", "ENSBTAT00000004135", "Q3SZJ5", "ENSBTAT00000027184", "F1N6T0", "ENSBTAT00000047968", "E1BBZ5", "ENSBTAT00000002161" ] }, "reaction_10056002": { "compartment": "compartment_5460", "id": "reaction_10056002", "reactome": "R-BTA-1008248", "name": "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159448", "species_113573" ], "products": [ "species_113581", "species_113525" ], "modifiers": [ [ "species_10055999", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022789" ] }, "reaction_10055847": { "compartment": "compartment_17906", "id": "reaction_10055847", "reactome": "R-BTA-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10055843" ], "products": [ "species_10055845" ], "modifiers": [], "additional_components": [ "D7GLD0", "ENSBTAT00000080672", "D7GLD0", "ENSBTAT00000080672" ] }, "reaction_10085753": { "compartment": "compartment_876", "id": "reaction_10085753", "reactome": "R-BTA-8870732", "name": "PSGs bind proteoglycans and TGF-beta1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10085749", "species_10085701" ], "products": [ "species_10085751" ], "modifiers": [], "additional_components": [ "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125", "A0A3Q1LX90", "ENSBTAT00000085051", "A0A3Q1M7Z2", "ENSBTAT00000081146", "A0A3Q1MQ27", "ENSBTAT00000069303", "A0A3Q1MS45", "ENSBTAT00000085051", "A0A3Q1LZ29", "ENSBTAT00000082766", "A0A3Q1N5R3", "ENSBTAT00000082452", "E1BKS1", "ENSBTAT00000020125" ] }, "reaction_10043323": { "compartment": "compartment_876", "id": "reaction_10043323", "reactome": "R-BTA-202709", "name": "JAM2 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319" ], "products": [ "species_10043321" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043355": { "compartment": "compartment_876", "id": "reaction_10043355", "reactome": "R-BTA-202717", "name": "Heterodimerization of CEACAMs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043351" ], "products": [ "species_10043353" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069303", "A0A3Q1MQ27", "ENSBTAT00000069303" ] }, "reaction_10043375": { "compartment": "compartment_876", "id": "reaction_10043375", "reactome": "R-BTA-202722", "name": "CD48 binds CD244", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043367", "species_10043371" ], "products": [ "species_10043373" ], "modifiers": [], "additional_components": [ "ENSBTAT00000014924", "ENSBTAT00000084280", "A0A3Q1LFU5", "ENSBTAT00000084280", "Q2KHZ6", "ENSBTAT00000014924" ] }, "reaction_10044024": { "compartment": "compartment_70101", "id": "reaction_10044024", "reactome": "R-BTA-210283", "name": "Interaction of PECAM-1 and PLC gamma1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044014", "species_10043197" ], "products": [ "species_10044022" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "ENSBTAT00000023383", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044030": { "compartment": "compartment_876", "id": "reaction_10044030", "reactome": "R-BTA-210285", "name": "Trans-homophilic interaction of PECAM-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044026" ], "products": [ "species_10044028" ], "modifiers": [], "additional_components": [ "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833" ] }, "reaction_10044034": { "compartment": "compartment_70101", "id": "reaction_10044034", "reactome": "R-BTA-210290", "name": "Interaction of PECAM-1 and SHIP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043216", "species_10044014" ], "products": [ "species_10044032" ], "modifiers": [], "additional_components": [ "ENSBTAT00000077857", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10044039": { "compartment": "compartment_70101", "id": "reaction_10044039", "reactome": "R-BTA-210291", "name": "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10044028" ], "products": [ "species_10044036", "species_29370" ], "modifiers": [ [ "species_10043788", "catalyst" ] ], "additional_components": [ "A0A3Q1MHJ9", "ENSBTAT00000086833", "A0A3Q1MHJ9", "ENSBTAT00000086833", "A7MB57", "ENSBTAT00000070883", "E1BIM8", "ENSBTAT00000011767", "A0JNB0", "ENSBTAT00000015730", "F1N261", "ENSBTAT00000075171" ] }, "reaction_10043393": { "compartment": "compartment_876", "id": "reaction_10043393", "reactome": "R-BTA-202724", "name": "P-selectin binds P-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043379", "species_10043389" ], "products": [ "species_10043391" ], "modifiers": [], "additional_components": [ "ENSBTAT00000029578", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "P98107", "ENSBTAT00000009612", "Q2KJA9", "ENSBTAT00000057091", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10043363": { "compartment": "compartment_876", "id": "reaction_10043363", "reactome": "R-BTA-202721", "name": "JAM2 binds JAM3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043319", "species_10043359" ], "products": [ "species_10043361" ], "modifiers": [], "additional_components": [ "ENSBTAT00000080737", "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263", "A4IFI9", "ENSBTAT00000080737" ] }, "reaction_10043347": { "compartment": "compartment_876", "id": "reaction_10043347", "reactome": "R-BTA-202714", "name": "CD58 binds CD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043343", "species_10043339" ], "products": [ "species_10043345" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084844", "ENSBTAT00000022936", "Q148M9", "ENSBTAT00000022936", "F6PZJ9", "ENSBTAT00000084844" ] }, "reaction_10043397": { "compartment": "compartment_876", "id": "reaction_10043397", "reactome": "R-BTA-202731", "name": "JAM3 dimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043359" ], "products": [ "species_10043395" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081263", "A0A3Q1M4F2", "ENSBTAT00000081263" ] }, "reaction_10043335": { "compartment": "compartment_876", "id": "reaction_10043335", "reactome": "R-BTA-202713", "name": "CD84 homodimerises", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10043331" ], "products": [ "species_10043333" ], "modifiers": [], "additional_components": [ "ENSBTAT00000053223", "F1N7U9", "ENSBTAT00000053223" ] }, "reaction_10066263": { "compartment": "compartment_876", "id": "reaction_10066263", "reactome": "R-BTA-2870221", "name": "E-selectin binds E-selectin ligand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10066259", "species_10043387" ], "products": [ "species_10066261" ], "modifiers": [], "additional_components": [ "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578", "ENSBTAT00000009612", "P98107", "ENSBTAT00000009612", "A0A3Q1LL67", "ENSBTAT00000083484", "A6QQP5", "ENSBTAT00000037368", "F1MS77", "ENSBTAT00000029578" ] }, "reaction_10038329": { "compartment": "compartment_984", "id": "reaction_10038329", "reactome": "R-BTA-158893", "name": "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038260", "species_10038324" ], "products": [ "species_10038326" ], "modifiers": [ [ "species_10038324", "catalyst" ] ], "additional_components": [ "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793", "P28800", "ENSBTAT00000027793", "E1B726", "ENSBTAT00000001674", "ENSBTAT00000027793" ] }, "reaction_10038285": { "compartment": "compartment_984", "id": "reaction_10038285", "reactome": "R-BTA-158750", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038272" ], "products": [ "species_10038260", "species_10038267" ], "modifiers": [ [ "species_10038272", "catalyst" ], [ "species_10038283", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "P60902", "ENSBTAT00000020150", "P04272", "ENSBTAT00000012655" ] }, "reaction_10038303": { "compartment": "compartment_984", "id": "reaction_10038303", "reactome": "R-BTA-158795", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267", "species_10038296" ], "products": [ "species_10038298" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038270": { "compartment": "compartment_984", "id": "reaction_10038270", "reactome": "R-BTA-158747", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038267" ], "products": [ "species_10038248" ], "modifiers": [ [ "species_10038260", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038288": { "compartment": "compartment_984", "id": "reaction_10038288", "reactome": "R-BTA-158756", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038248" ], "products": [ "species_10038254" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038307": { "compartment": "compartment_984", "id": "reaction_10038307", "reactome": "R-BTA-158800", "name": "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038296", "species_10038248" ], "products": [ "species_10038305" ], "modifiers": [ [ "species_10038300", "catalyst" ] ], "additional_components": [ "ENSBTAT00000019232", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIJ9", "ENSBTAT00000019232", "A0A452DIJ9", "ENSBTAT00000019232" ] }, "reaction_10038290": { "compartment": "compartment_984", "id": "reaction_10038290", "reactome": "R-BTA-158781", "name": "crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_157771", "species_10038265" ], "products": [ "species_10038267" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642" ] }, "reaction_10038292": { "compartment": "compartment_984", "id": "reaction_10038292", "reactome": "R-BTA-158784", "name": "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038252", "species_10038267" ], "products": [ "species_10038272" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10038263": { "compartment": "compartment_984", "id": "reaction_10038263", "reactome": "R-BTA-158744", "name": "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038254" ], "products": [ "species_10038260", "species_10038248" ], "modifiers": [ [ "species_10038254", "catalyst" ] ], "additional_components": [ "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674", "E1B726", "ENSBTAT00000001674", "A0A452DIF6", "ENSBTAT00000001642", "A0A452DIF6", "ENSBTAT00000001642", "E1B726", "ENSBTAT00000001674" ] }, "reaction_10057598": { "compartment": "compartment_984", "id": "reaction_10057598", "reactome": "R-BTA-1297333", "name": "Association of Acrosin Heavy and Light Chain", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057594", "species_10057592" ], "products": [ "species_10057596" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "G5E5C6", "ENSBTAT00000013434" ] }, "reaction_10057605": { "compartment": "compartment_984", "id": "reaction_10057605", "reactome": "R-BTA-1297354", "name": "Acrosin Cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10057602" ], "products": [ "species_10057594", "species_10057592" ], "modifiers": [ [ "species_10057602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434", "ENSBTAT00000013434" ] }, "reaction_10091211": { "compartment": "compartment_7660", "id": "reaction_10091211", "reactome": "R-BTA-9629195", "name": "NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091207", "species_10091201" ], "products": [ "species_10091209" ], "modifiers": [], "additional_components": [ "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10091566": { "compartment": "compartment_70101", "id": "reaction_10091566", "reactome": "R-BTA-9656947", "name": "OGG1beta translocates to mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091562" ], "products": [ "species_10091564" ], "modifiers": [], "additional_components": [ "ENSBTAT00000010226", "ENSBTAT00000010226" ] }, "reaction_10035854": { "compartment": "compartment_7660", "id": "reaction_10035854", "reactome": "R-BTA-76052", "name": "Binding of TFIIIA To type 1 Promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76050", "species_10035850" ], "products": [ "species_10035852" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016732", "F1MUY9", "ENSBTAT00000016732" ] }, "reaction_10036760": { "compartment": "compartment_7660", "id": "reaction_10036760", "reactome": "R-BTA-110243", "name": "Excision of 8-oxoguanine by OGG1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036755" ], "products": [ "species_10036757", "species_110242" ], "modifiers": [ [ "species_10036755", "catalyst" ] ], "additional_components": [ "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226", "F1MPV2", "ENSBTAT00000010226" ] }, "reaction_10091240": { "compartment": "compartment_7660", "id": "reaction_10091240", "reactome": "R-BTA-9629492", "name": "NEIL3 cleaves spiroiminodihydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091237" ], "products": [ "species_9629439", "species_10091230" ], "modifiers": [ [ "species_10091237", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036782": { "compartment": "compartment_7660", "id": "reaction_10036782", "reactome": "R-BTA-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036777" ], "products": [ "species_5635947", "species_10036779" ], "modifiers": [ [ "species_10036777", "catalyst" ] ], "additional_components": [ "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928", "F1N4K4", "ENSBTAT00000014928" ] }, "reaction_10036798": { "compartment": "compartment_7660", "id": "reaction_10036798", "reactome": "R-BTA-110250", "name": "Cleavage of ethenoadenine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036795" ], "products": [ "species_10036788", "species_110249" ], "modifiers": [ [ "species_10036795", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091233": { "compartment": "compartment_7660", "id": "reaction_10091233", "reactome": "R-BTA-9629470", "name": "NEIL3 cleaves 5-guanidinohydantoin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091226" ], "products": [ "species_10091230", "species_9629218" ], "modifiers": [ [ "species_10091226", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434", "A0A3Q1M1H9", "ENSBTAT00000084434" ] }, "reaction_10036805": { "compartment": "compartment_7660", "id": "reaction_10036805", "reactome": "R-BTA-110251", "name": "Cleavage of hypoxanthine by MPG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036802" ], "products": [ "species_10036788", "species_29850" ], "modifiers": [ [ "species_10036802", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10036791": { "compartment": "compartment_7660", "id": "reaction_10036791", "reactome": "R-BTA-110248", "name": "Cleavage of 3-methyladenine by MPG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036786" ], "products": [ "species_10036788", "species_30947" ], "modifiers": [ [ "species_10036786", "catalyst" ] ], "additional_components": [ "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548", "F1MKN2", "ENSBTAT00000037548" ] }, "reaction_10091222": { "compartment": "compartment_7660", "id": "reaction_10091222", "reactome": "R-BTA-9629216", "name": "NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091209" ], "products": [ "species_10091219", "species_9629218" ], "modifiers": [ [ "species_10091209", "catalyst" ] ], "additional_components": [ "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "A0A3Q1M1H9", "ENSBTAT00000084434", "Q0VCT3", "ENSBTAT00000020830", "F1MMS4", "ENSBTAT00000010016", "A3KN17", "ENSBTAT00000003522", "E1BGK3", "ENSBTAT00000017541", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10072876": { "compartment": "compartment_7660", "id": "reaction_10072876", "reactome": "R-BTA-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072868", "species_10072872" ], "products": [ "species_10072874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000131", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10072883": { "compartment": "compartment_7660", "id": "reaction_10072883", "reactome": "R-BTA-5653786", "name": "USP43 deISGylates ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10072874" ], "products": [ "species_10072868", "species_10072880", "species_10072878" ], "modifiers": [ [ "species_10072874", "catalyst" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131", "ENSBTAT00000000131", "ENSBTAT00000019573", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "Q3ZBW4", "ENSBTAT00000007967", "O02741", "ENSBTAT00000019573", "E1BKF4", "ENSBTAT00000000131" ] }, "reaction_10073302": { "compartment": "compartment_7660", "id": "reaction_10073302", "reactome": "R-BTA-5655193", "name": "KIAA0101 double monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073294", "species_10036828" ], "products": [ "species_10073300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000054209", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q5E9B2", "ENSBTAT00000054209" ] }, "reaction_10044547": { "compartment": "compartment_984", "id": "reaction_10044547", "reactome": "R-BTA-264695", "name": "cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171149", "species_194276" ], "products": [ "species_194236", "species_171076" ], "modifiers": [ [ "species_10044544", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024018" ] }, "reaction_10088982": { "compartment": "compartment_984", "id": "reaction_10088982", "reactome": "R-BTA-8980228", "name": "LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088979", "catalyst" ] ], "additional_components": [ "A0A3Q1LR40", "ENSBTAT00000075023" ] }, "reaction_10084509": { "compartment": "compartment_876", "id": "reaction_10084509", "reactome": "R-BTA-8857928", "name": "GPIHBP1 binds HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077472", "species_10077480" ], "products": [ "species_10077482" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071232", "species_1678620", "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232" ] }, "reaction_10077487": { "compartment": "compartment_876", "id": "reaction_10077487", "reactome": "R-BTA-6784676", "name": "PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077482" ], "products": [ "species_10077476", "species_10077472", "species_1678620" ], "modifiers": [ [ "species_10077484", "catalyst" ] ], "additional_components": [ "species_1678620", "P11151", "ENSBTAT00000017086", "A0A3Q1MPP4", "ENSBTAT00000071232", "ENSBTAT00000017086", "ENSBTAT00000071232", "ENSBTAT00000077745" ] }, "reaction_10077489": { "compartment": "compartment_984", "id": "reaction_10077489", "reactome": "R-BTA-6784861", "name": "HSPG binds LPL dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077478", "species_1678620" ], "products": [ "species_10077480" ], "modifiers": [], "additional_components": [ "P11151", "ENSBTAT00000017086", "species_1678620", "P11151", "ENSBTAT00000017086" ] }, "reaction_10077593": { "compartment": "compartment_7660", "id": "reaction_10077593", "reactome": "R-BTA-6785607", "name": "FANCM binds FAAP24", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077506", "species_10077502" ], "products": [ "species_10077508" ], "modifiers": [], "additional_components": [ "ENSBTAT00000071085", "ENSBTAT00000065656", "Q2KHY5", "ENSBTAT00000065656", "A0A3Q1MT39", "ENSBTAT00000071085" ] }, "reaction_10077625": { "compartment": "compartment_7660", "id": "reaction_10077625", "reactome": "R-BTA-6785732", "name": "DNA nucleases bind monoubiquitinated ID2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036659", "species_10077619", "species_10077582", "species_10075163", "species_10077609" ], "products": [ "species_10077623" ], "modifiers": [], "additional_components": [ "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "E1BN11", "ENSBTAT00000026896", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "ENSBTAT00000085708", "Q32PI0", "ENSBTAT00000011384", "F1N7Q0", "ENSBTAT00000005923", "G3N153", "ENSBTAT00000065898", "E1B8J2", "ENSBTAT00000053203", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BN11", "ENSBTAT00000026896", "Q1LZ75", "ENSBTAT00000023078", "E1BKV9", "ENSBTAT00000046336", "A0A3Q1MJE2", "ENSBTAT00000085708" ] }, "reaction_10077591": { "compartment": "compartment_7660", "id": "reaction_10077591", "reactome": "R-BTA-6785361", "name": "Monoubiquitination of FANCD2:FANCI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10077569", "species_10036828" ], "products": [ "species_10077588", "species_10077582" ], "modifiers": [ [ "species_10077569", "catalyst" ] ], "additional_components": [ "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "A0A3Q1MQ26", "ENSBTAT00000068467", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "E1BE83", "ENSBTAT00000013299", "Q2TBR7", "ENSBTAT00000017996", "Q2NKU0", "ENSBTAT00000005369", "A0A3Q1MT39", "ENSBTAT00000071085", "Q2KHY5", "ENSBTAT00000065656", "A0A452DIP1", "ENSBTAT00000018787", "F1MWV7", "ENSBTAT00000009509", "E1B6X8", "ENSBTAT00000002478", "A6QQ29", "ENSBTAT00000056722", "G3X787", "ENSBTAT00000082853", "Q2TBN8", "ENSBTAT00000007713", "A0A3Q1MQ26", "ENSBTAT00000068467" ] }, "reaction_10035372": { "compartment": "compartment_5460", "id": "reaction_10035372", "reactome": "R-BTA-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10035369", "catalyst" ] ], "additional_components": [ "ENSBTAT00000005088" ] }, "reaction_10035363": { "compartment": "compartment_5460", "id": "reaction_10035363", "reactome": "R-BTA-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113529", "species_73909", "species_29362" ], "products": [ "species_113526", "species_73911" ], "modifiers": [ [ "species_10035360", "catalyst" ] ], "additional_components": [ "Q02337", "ENSBTAT00000082799" ] }, "reaction_10049883": { "compartment": "compartment_70101", "id": "reaction_10049883", "reactome": "R-BTA-446322", "name": "PARVA associates with Paxillin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049875" ], "products": [ "species_10049881" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000024101", "F1MFD1", "ENSBTAT00000024101", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10049312": { "compartment": "compartment_70101", "id": "reaction_10049312", "reactome": "R-BTA-432946", "name": "PARVB/Affixin interacts with alpha PIX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049308", "species_10048105" ], "products": [ "species_10049310" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084501", "ENSBTAT00000083031", "A0A3Q1LKT5", "ENSBTAT00000083031", "A0A3Q1M7B6", "ENSBTAT00000084501" ] }, "reaction_10049891": { "compartment": "compartment_70101", "id": "reaction_10049891", "reactome": "R-BTA-446372", "name": "Association of PARVA with TESK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049879", "species_10049887" ], "products": [ "species_10049889" ], "modifiers": [], "additional_components": [ "ENSBTAT00000081787", "ENSBTAT00000082961", "A0A3Q1MET9", "ENSBTAT00000082961", "A0A3Q1LMM6", "ENSBTAT00000081787" ] }, "reaction_10038942": { "compartment": "compartment_7660", "id": "reaction_10038942", "reactome": "R-BTA-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10035753" ], "modifiers": [], "additional_components": [ "ENSBTAT00000083979" ] }, "reaction_10036844": { "compartment": "compartment_7660", "id": "reaction_10036844", "reactome": "R-BTA-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036840", "species_10036809" ], "products": [ "species_10036842" ], "modifiers": [], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000066497", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10036853": { "compartment": "compartment_7660", "id": "reaction_10036853", "reactome": "R-BTA-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10036842" ], "products": [ "species_10036850" ], "modifiers": [ [ "species_10036842", "catalyst" ] ], "additional_components": [ "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A0A3Q1MPW7", "ENSBTAT00000066497", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073275": { "compartment": "compartment_7660", "id": "reaction_10073275", "reactome": "R-BTA-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073270", "species_29358" ], "products": [ "species_113582", "species_10073272", "species_10036857" ], "modifiers": [ [ "species_10073270", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "A5D979", "ENSBTAT00000008030", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030", "F1N7U2", "ENSBTAT00000042613", "A0A3Q1N3E8", "ENSBTAT00000080740" ] }, "reaction_10073290": { "compartment": "compartment_7660", "id": "reaction_10073290", "reactome": "R-BTA-5655170", "name": "RCHY1 monoubiquitinates POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036828", "species_10073277" ], "products": [ "species_10073287", "species_10036867" ], "modifiers": [ [ "species_10073277", "catalyst" ] ], "additional_components": [ "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "F1MZ79", "ENSBTAT00000007900", "ENSBTAT00000009461", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036879": { "compartment": "compartment_7660", "id": "reaction_10036879", "reactome": "R-BTA-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036863", "species_29604" ], "products": [ "species_10036876", "species_113541" ], "modifiers": [ [ "species_10036863", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073279": { "compartment": "compartment_7660", "id": "reaction_10073279", "reactome": "R-BTA-5655142", "name": "RCHY1 binds POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036867", "species_10036857" ], "products": [ "species_10073277" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009461", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A4IFE2", "ENSBTAT00000009461" ] }, "reaction_10036869": { "compartment": "compartment_7660", "id": "reaction_10036869", "reactome": "R-BTA-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036861", "species_10036857" ], "products": [ "species_10036863" ], "modifiers": [ [ "species_10036867", "inhibitor" ] ], "additional_components": [ "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000007900", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "ENSBTAT00000009461" ] }, "reaction_10036886": { "compartment": "compartment_7660", "id": "reaction_10036886", "reactome": "R-BTA-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10036876" ], "products": [ "species_10036883", "species_113541" ], "modifiers": [ [ "species_10036876", "catalyst" ] ], "additional_components": [ "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967" ] }, "reaction_10073254": { "compartment": "compartment_7660", "id": "reaction_10073254", "reactome": "R-BTA-5654986", "name": "SPRTN binds monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10073250", "species_10036883" ], "products": [ "species_10073252" ], "modifiers": [], "additional_components": [ "ENSBTAT00000008030", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "F1MZ79", "ENSBTAT00000007900", "A0A3Q1LY33", "ENSBTAT00000085991", "A0A3Q1M1J3", "ENSBTAT00000071469", "Q2TBV1", "ENSBTAT00000014278", "A0A3Q1N5S1", "ENSBTAT00000076791", "Q2KI86", "ENSBTAT00000008174", "Q3SZ11", "ENSBTAT00000017525", "A0A3Q1LU30", "ENSBTAT00000087088", "P63048", "ENSBTAT00000010176", "P0CG53", "ENSBTAT00000022919", "Q3ZBW4", "ENSBTAT00000007967", "A5D979", "ENSBTAT00000008030" ] }, "reaction_10090392": { "compartment": "compartment_70101", "id": "reaction_10090392", "reactome": "R-BTA-9020274", "name": "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9025012" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090394": { "compartment": "compartment_70101", "id": "reaction_10090394", "reactome": "R-BTA-9020275", "name": "ALOX15 oxidises DHA to 17(S)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024012" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090462": { "compartment": "compartment_70101", "id": "reaction_10090462", "reactome": "R-BTA-9024881", "name": "ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_9024012" ], "products": [ "species_29364", "species_9024873" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090384": { "compartment": "compartment_70101", "id": "reaction_10090384", "reactome": "R-BTA-9020261", "name": "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9024011" ], "products": [ "species_9024522" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090464": { "compartment": "compartment_70101", "id": "reaction_10090464", "reactome": "R-BTA-9024983", "name": "ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9025012", "species_29366" ], "products": [ "species_29364", "species_9025001" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10090458": { "compartment": "compartment_70101", "id": "reaction_10090458", "reactome": "R-BTA-9024766", "name": "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024764", "species_29360" ], "products": [ "species_9024799", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "CHEBI:132797", "CHEBI:132800", "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090390": { "compartment": "compartment_70101", "id": "reaction_10090390", "reactome": "R-BTA-9020273", "name": "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024012" ], "products": [ "species_29356", "species_9024815", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090388": { "compartment": "compartment_70101", "id": "reaction_10090388", "reactome": "R-BTA-9020271", "name": "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_9024522" ], "products": [ "species_29356", "species_9024463", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10062377": { "compartment": "compartment_984", "id": "reaction_10062377", "reactome": "R-BTA-2002440", "name": "Removal of fibrillar collagen C-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062335" ], "products": [ "species_10058697" ], "modifiers": [ [ "species_10062368", "catalyst" ], [ "species_10062375", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "F1N0X6", "ENSBTAT00000007834", "Q2HJB6", "ENSBTAT00000027347", "F1MKP1", "ENSBTAT00000021330" ] }, "reaction_10061787": { "compartment": "compartment_17957", "id": "reaction_10061787", "reactome": "R-BTA-1980233", "name": "Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_10061734", "species_1650779" ], "products": [ "species_1650769", "species_159751", "species_10061784" ], "modifiers": [ [ "species_10061734", "catalyst" ] ], "additional_components": [ "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067", "CHEBI:29073", "A6QLY3", "ENSBTAT00000027999", "species_71067" ] }, "reaction_10060187": { "compartment": "compartment_17957", "id": "reaction_10060187", "reactome": "R-BTA-1614460", "name": "Dimerization of procollagen type VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060183" ], "products": [ "species_10060185" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10087626": { "compartment": "compartment_17957", "id": "reaction_10087626", "reactome": "R-BTA-8948228", "name": "COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10061921", "species_10061791" ], "products": [ "species_10061923" ], "modifiers": [], "additional_components": [ "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10062058": { "compartment": "compartment_17957", "id": "reaction_10062058", "reactome": "R-BTA-1981120", "name": "Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1981137", "species_10061923" ], "products": [ "species_10062055", "species_158602" ], "modifiers": [ [ "species_10061923", "catalyst" ] ], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322", "F1N0V8", "ENSBTAT00000050322" ] }, "reaction_10087628": { "compartment": "compartment_17957", "id": "reaction_10087628", "reactome": "R-BTA-8948231", "name": "COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062055" ], "products": [ "species_10062053", "species_10061791" ], "modifiers": [], "additional_components": [ "F1N0V8", "ENSBTAT00000050322", "ENSBTAT00000050322" ] }, "reaction_10060191": { "compartment": "compartment_17957", "id": "reaction_10060191", "reactome": "R-BTA-1614461", "name": "Tetramerization of procollagen VI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10060185" ], "products": [ "species_10060189" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663" ] }, "reaction_10064337": { "compartment": "compartment_17957", "id": "reaction_10064337", "reactome": "R-BTA-2152276", "name": "Secretion of transmembrane collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062852" ], "products": [ "species_10064335" ], "modifiers": [], "additional_components": [ "F1MSJ7", "ENSBTAT00000017548", "F6RND5", "ENSBTAT00000039811", "E1BKJ9", "ENSBTAT00000044319", "F1MSJ7", "ENSBTAT00000017548", "E1BKJ9", "ENSBTAT00000044319", "F6RND5", "ENSBTAT00000039811" ] }, "reaction_10062352": { "compartment": "compartment_984", "id": "reaction_10062352", "reactome": "R-BTA-2002428", "name": "Removal of fibrillar collagen N-propeptides", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10062205" ], "products": [ "species_10062335" ], "modifiers": [ [ "species_10062349", "catalyst" ] ], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "A0A3Q1MDT9", "ENSBTAT00000084344", "G3MZI7", "ENSBTAT00000063052", "F1MJQ6", "ENSBTAT00000013440", "E1BEV7", "ENSBTAT00000001218", "E1BC50", "ENSBTAT00000061447", "E1BFV4", "ENSBTAT00000028224" ] }, "reaction_10063799": { "compartment": "compartment_17957", "id": "reaction_10063799", "reactome": "R-BTA-2089971", "name": "Secretion of collagens", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10063637" ], "products": [ "species_10063797", "species_10062846" ], "modifiers": [], "additional_components": [ "Q2KJH6", "ENSBTAT00000083385", "E1BI98", "ENSBTAT00000015668", "E1BB91", "ENSBTAT00000018479", "F1MKG2", "ENSBTAT00000025663", "A0A3Q1M646", "ENSBTAT00000081723", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "G3MZI7", "ENSBTAT00000063052", "P02459", "ENSBTAT00000017505", "F1MSJ7", "ENSBTAT00000017548", "F1MJR6", "ENSBTAT00000083731", "A7E303", "ENSBTAT00000018159", "A0A3Q1M0N0", "ENSBTAT00000072268", "A0A3Q1MQC5", "ENSBTAT00000074238", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "G3MXK9", "ENSBTAT00000065364", "A0A3Q1MQC5", "ENSBTAT00000074238", "A0A3Q1M0N0", "ENSBTAT00000072268", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "A0A3Q1LYA4", "ENSBTAT00000067622", "G3N021", "ENSBTAT00000063888", "E1BKJ9", "ENSBTAT00000044319", "ENSBTAT00000083385" ] }, "reaction_10064491": { "compartment": "compartment_70101", "id": "reaction_10064491", "reactome": "R-BTA-2161775", "name": "ALOX12 oxidises LTA4 to LXA4/B4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9032038", "species_29368" ], "products": [ "species_2161856" ], "modifiers": [ [ "species_10064488", "catalyst" ] ], "additional_components": [ "CHEBI:6499", "species_2161759", "species_71067", "F1MFA8", "ENSBTAT00000029240" ] }, "reaction_10064500": { "compartment": "compartment_70101", "id": "reaction_10064500", "reactome": "R-BTA-2161779", "name": "LXA4 is oxidised to 15k-LXA4 by HPGD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161759", "species_29360" ], "products": [ "species_70106", "species_2142761", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10065691": { "compartment": "compartment_984", "id": "reaction_10065691", "reactome": "R-BTA-2466106", "name": "BGN binds Collagen types I, VI, (IX)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059282", "species_10062553" ], "products": [ "species_10065689" ], "modifiers": [], "additional_components": [ "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000047242", "P21809", "ENSBTAT00000047242", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10065300": { "compartment": "compartment_984", "id": "reaction_10065300", "reactome": "R-BTA-2327909", "name": "DCN binds collagen I, II, III, VI fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065296", "species_10065294" ], "products": [ "species_10065298" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "ENSBTAT00000004562", "P21793", "ENSBTAT00000004562", "P02459", "ENSBTAT00000017505", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479" ] }, "reaction_10064953": { "compartment": "compartment_984", "id": "reaction_10064953", "reactome": "R-BTA-2213201", "name": "Formation of collagen fibres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058703" ], "products": [ "species_10064951" ], "modifiers": [], "additional_components": [ "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10064959": { "compartment": "compartment_984", "id": "reaction_10064959", "reactome": "R-BTA-2213207", "name": "Formation of collagen networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064955" ], "products": [ "species_10064957" ], "modifiers": [], "additional_components": [ "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A7E303", "ENSBTAT00000018159", "F1MJR6", "ENSBTAT00000083731", "E1BI98", "ENSBTAT00000015668", "F1MKG2", "ENSBTAT00000025663", "E1BB91", "ENSBTAT00000018479", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10058705": { "compartment": "compartment_984", "id": "reaction_10058705", "reactome": "R-BTA-1474266", "name": "Formation of collagen fibrils", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10058697" ], "products": [ "species_10058703" ], "modifiers": [], "additional_components": [ "A0A3Q1M646", "ENSBTAT00000081723", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "P02459", "ENSBTAT00000017505", "G3MZI7", "ENSBTAT00000063052", "A0A3Q1MDT9", "ENSBTAT00000084344", "F1MJQ6", "ENSBTAT00000013440", "A0A3Q1M646", "ENSBTAT00000081723" ] }, "reaction_10065929": { "compartment": "compartment_984", "id": "reaction_10065929", "reactome": "R-BTA-2559639", "name": "Collagen type IV sulfilimine cross-linking by peroxidasin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_351629" ], "products": [ "species_10065920" ], "modifiers": [ [ "species_10065926", "catalyst" ] ], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "CHEBI:15858", "A0A3Q1LMN6", "ENSBTAT00000073028" ] }, "reaction_10035464": { "compartment": "compartment_70101", "id": "reaction_10035464", "reactome": "R-BTA-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_83956" ], "products": [ "species_31633", "species_30064" ], "modifiers": [ [ "species_10035461", "catalyst" ] ], "additional_components": [ "species_29426", "F1MLX9", "ENSBTAT00000015339" ] }, "reaction_10088571": { "compartment": "compartment_70101", "id": "reaction_10088571", "reactome": "R-BTA-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109327", "species_29356" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10088568", "catalyst" ] ], "additional_components": [ "ENSBTAT00000026530" ] }, "reaction_10035453": { "compartment": "compartment_70101", "id": "reaction_10035453", "reactome": "R-BTA-74242", "name": "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500172" ], "products": [ "species_113599", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:28997", "CHEBI:17596", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036207": { "compartment": "compartment_984", "id": "reaction_10036207", "reactome": "R-BTA-109278", "name": "NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500101" ], "products": [ "species_500104", "species_109277" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_2509792", "species_76577", "species_113578", "species_109386", "CHEBI:17596", "CHEBI:16750", "species_83909", "CHEBI:17256", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035455": { "compartment": "compartment_70101", "id": "reaction_10035455", "reactome": "R-BTA-74249", "name": "(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500245" ], "products": [ "species_83956", "species_500244" ], "modifiers": [ [ "species_10035450", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:16750", "CHEBI:28542", "species_112016", "A0A452DJA8", "ENSBTAT00000016346" ] }, "reaction_10036238": { "compartment": "compartment_70101", "id": "reaction_10036238", "reactome": "R-BTA-109415", "name": "AMP + H2O => adenosine + orthophosphate [NT5C1B]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29372", "species_83909" ], "modifiers": [ [ "species_10036235", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "ENSBTAT00000006950" ] }, "reaction_10036256": { "compartment": "compartment_70101", "id": "reaction_10036256", "reactome": "R-BTA-109470", "name": "(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500120", "species_29356" ], "products": [ "species_29372", "species_500118" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "species_2509792", "species_2509805", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "CHEBI:17596", "CHEBI:16750", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10036231": { "compartment": "compartment_70101", "id": "reaction_10036231", "reactome": "R-BTA-109387", "name": "(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500125" ], "products": [ "species_29372", "species_500124" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_76577", "species_2509792", "species_2509805", "species_109386", "species_113578", "species_109327", "CHEBI:17172", "CHEBI:28997", "species_83909", "CHEBI:17256", "CHEBI:17596", "CHEBI:16750", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10053044": { "compartment": "compartment_70101", "id": "reaction_10053044", "reactome": "R-BTA-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10053039", "species_113592" ], "products": [ "species_10053041", "species_29370" ], "modifiers": [ [ "species_10053039", "catalyst" ] ], "additional_components": [ "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868", "A0A3Q1MH45", "ENSBTAT00000017703", "F6Q087", "ENSBTAT00000004656", "species_29420", "Q3ZBJ1", "ENSBTAT00000011684", "E1BMM0", "ENSBTAT00000061170", "Q3T0F4", "ENSBTAT00000020719", "Q32PD5", "ENSBTAT00000032643", "E1BHA5", "ENSBTAT00000032643", "Q3T0V4", "ENSBTAT00000018491", "Q76I82", "ENSBTAT00000069480", "A0A3Q1LLI8", "ENSBTAT00000072836", "Q56JV9", "ENSBTAT00000013079", "Q3T0X6", "ENSBTAT00000028093", "P62276", "ENSBTAT00000077396", "Q3T169", "ENSBTAT00000003962", "A0A3Q1MFH1", "ENSBTAT00000084646", "A0A3Q1LU30", "ENSBTAT00000087088", "A0A3Q1LRX4", "ENSBTAT00000085499", "A0A3Q1MIM5", "ENSBTAT00000085499", "Q56JX6", "ENSBTAT00000003201", "Q56JU9", "ENSBTAT00000073736", "F1MR01", "ENSBTAT00000075650", "A0A3Q1LNR2", "ENSBTAT00000075650", "Q56JX5", "ENSBTAT00000040046", "Q2KHT7", "ENSBTAT00000018414", "Q56JX8", "ENSBTAT00000055693", "A0A3Q1M5N2", "ENSBTAT00000085238", "E1BEQ3", "ENSBTAT00000063143", "Q3T199", "ENSBTAT00000063143", "Q32PB8", "ENSBTAT00000027713", "A0A3Q1M9K1", "ENSBTAT00000082341", "A0A3Q1LNI8", "ENSBTAT00000082341", "E1B7E5", "ENSBTAT00000080007", "E1BCB7", "ENSBTAT00000025298", "A0A3Q1LNV2", "ENSBTAT00000080007", "A0A3Q1MSH8", "ENSBTAT00000080007", "A2VE06", "ENSBTAT00000063866", "G3N267", "ENSBTAT00000063866", "E1BGR7", "ENSBTAT00000063866", "F1MJH2", "ENSBTAT00000063866", "P79103", "ENSBTAT00000025024", "A0A3Q1LQD0", "ENSBTAT00000063866", "G3N0K3", "ENSBTAT00000063866", "A0A3Q1N412", "ENSBTAT00000019214", "E1B8K9", "ENSBTAT00000019214", "A0A3Q1MBL4", "ENSBTAT00000020462", "Q3ZBH8", "ENSBTAT00000025484", "A0A452DJF6", "ENSBTAT00000055065", "Q9XSI3", "ENSBTAT00000020266", "Q861S4", "ENSBTAT00000002160", "A0A3Q1LR67", "ENSBTAT00000071569", "Q3T003", "ENSBTAT00000021033", "E1BII3", "ENSBTAT00000037203", "P61257", "ENSBTAT00000016378", "Q3T057", "ENSBTAT00000004190", "P61356", "ENSBTAT00000023183", "Q862I1", "ENSBTAT00000017905", "P39872", "ENSBTAT00000004188", "Q58DT1", "ENSBTAT00000026826", "A0A452DIZ2", "ENSBTAT00000027850", "Q58DQ3", "ENSBTAT00000033359", "Q5E9E6", "ENSBTAT00000025963", "Q3T0S6", "ENSBTAT00000037367", "A0A3Q1M4M0", "ENSBTAT00000036905", "Q2TBQ5", "ENSBTAT00000015358", "P61284", "ENSBTAT00000009155", "G8JKV5", "ENSBTAT00000084955", "Q3SYR7", "ENSBTAT00000019298", "A0A3Q1LH67", "ENSBTAT00000035330", "A0A3Q1LST0", "ENSBTAT00000020729", "Q5EAD6", "ENSBTAT00000020729", "Q3T171", "ENSBTAT00000075433", "E1BHM9", "ENSBTAT00000015544", "Q3MIC0", "ENSBTAT00000071825", "P79244", "ENSBTAT00000006781", "P63048", "ENSBTAT00000010176", "Q58DW0", "ENSBTAT00000006866", "F1MDN4", "ENSBTAT00000055086", "Q32PB9", "ENSBTAT00000042547", "Q58DW5", "ENSBTAT00000002626", "P42899", "ENSBTAT00000002326", "Q56K14", "ENSBTAT00000024376", "A0A452DJ34", "ENSBTAT00000031754", "Q56K03", "ENSBTAT00000066379", "F1MG09", "ENSBTAT00000050149", "Q3SZ59", "ENSBTAT00000050149", "Q3T0D5", "ENSBTAT00000069699", "Q58DW3", "ENSBTAT00000024788", "Q3SZQ6", "ENSBTAT00000020323", "Q3T051", "ENSBTAT00000087168", "Q3MHM7", "ENSBTAT00000004161", "F1ML72", "ENSBTAT00000071912", "Q2NL22", "ENSBTAT00000021327", "Q0VC92", "ENSBTAT00000025615", "A0A452DHY5", "ENSBTAT00000004528", "A0A3Q1LRF2", "ENSBTAT00000075557", "A6QR16", "ENSBTAT00000078713", "F1MBL6", "ENSBTAT00000027632", "E1BEK9", "ENSBTAT00000027868" ] }, "reaction_10090377": { "compartment": "compartment_70101", "id": "reaction_10090377", "reactome": "R-BTA-9018880", "name": "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2026977", "species_29368" ], "products": [ "species_9022921" ], "modifiers": [ [ "species_10064543", "catalyst" ] ], "additional_components": [ "species_9023653", "species_9020583", "F1MNI5", "ENSBTAT00000018774", "CHEBI:26355" ] }, "reaction_10090440": { "compartment": "compartment_70101", "id": "reaction_10090440", "reactome": "R-BTA-9023968", "name": "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9022660", "species_29360" ], "products": [ "species_9023963", "species_73473" ], "modifiers": [ [ "species_10064497", "catalyst" ] ], "additional_components": [ "Q309F3", "ENSBTAT00000027024" ] }, "reaction_10090396": { "compartment": "compartment_70101", "id": "reaction_10090396", "reactome": "R-BTA-9020610", "name": "ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_9020474" ], "products": [ "species_9022679" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10090374": { "compartment": "compartment_70101", "id": "reaction_10090374", "reactome": "R-BTA-9018868", "name": "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9020583", "species_29450" ], "products": [ "species_29356", "species_9020474", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090379": { "compartment": "compartment_70101", "id": "reaction_10090379", "reactome": "R-BTA-9018895", "name": "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023653", "species_29450" ], "products": [ "species_29356", "species_9023651", "species_111745" ], "modifiers": [ [ "species_10090371", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070793" ] }, "reaction_10090382": { "compartment": "compartment_70101", "id": "reaction_10090382", "reactome": "R-BTA-9018907", "name": "ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023651", "species_29368" ], "products": [ "species_9023644" ], "modifiers": [ [ "species_10064558", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015911" ] }, "reaction_10065866": { "compartment": "compartment_876", "id": "reaction_10065866", "reactome": "R-BTA-2534359", "name": "CatSper Channel Mediated Calcium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74112" ], "products": [ "species_74016" ], "modifiers": [ [ "species_10065861", "catalyst" ] ], "additional_components": [ "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065884": { "compartment": "compartment_876", "id": "reaction_10065884", "reactome": "R-BTA-2534378", "name": "Hv1 Mediated H+ Permeability", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1132304" ], "products": [ "species_351626" ], "modifiers": [ [ "species_10065881", "catalyst" ] ], "additional_components": [ "A0A3Q1NF89", "ENSBTAT00000076616" ] }, "reaction_10065886": { "compartment": "compartment_984", "id": "reaction_10065886", "reactome": "R-BTA-2534388", "name": "Progesterone Activation Of CatSper", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065863", "species_1449667" ], "products": [ "species_10065861" ], "modifiers": [], "additional_components": [ "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586", "species_193055", "E1B9V5", "ENSBTAT00000024903", "A0A452DHU9", "ENSBTAT00000002352", "F1MED0", "ENSBTAT00000056871", "E1BGU6", "ENSBTAT00000045580", "F1N390", "ENSBTAT00000019622", "G3MZP0", "ENSBTAT00000063395", "F1N4E7", "ENSBTAT00000019586" ] }, "reaction_10065875": { "compartment": "compartment_876", "id": "reaction_10065875", "reactome": "R-BTA-2534365", "name": "Slo3 Potassium Transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29804" ], "products": [ "species_74126" ], "modifiers": [ [ "species_10065872", "catalyst" ] ], "additional_components": [ "A0A3S5ZP59", "ENSBTAT00000038859" ] }, "reaction_10076856": { "compartment": "compartment_984", "id": "reaction_10076856", "reactome": "R-BTA-5696131", "name": "AOC1 deaminates Hist", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_390899", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696128" ], "modifiers": [ [ "species_10076853", "catalyst" ] ], "additional_components": [ "Q3MHQ1", "ENSBTAT00000007133", "species_74016", "CHEBI:28694" ] }, "reaction_10077496": { "compartment": "compartment_70101", "id": "reaction_10077496", "reactome": "R-BTA-6784959", "name": "BPHL hydrolyses VACV to ACV", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6784964" ], "products": [ "species_29702", "species_561052" ], "modifiers": [ [ "species_10077493", "catalyst" ] ], "additional_components": [ "ENSBTAT00000008368" ] }, "reaction_10076475": { "compartment": "compartment_12045", "id": "reaction_10076475", "reactome": "R-BTA-5694077", "name": "EPHX1 hydrates BaP4,5O to BaP4,5-DHD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694080" ], "products": [ "species_5694091" ], "modifiers": [ [ "species_10076472", "catalyst" ] ], "additional_components": [ "ENSBTAT00000083641" ] }, "reaction_10076863": { "compartment": "compartment_984", "id": "reaction_10076863", "reactome": "R-BTA-5696146", "name": "AOC2 deaminates TYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5696181", "species_352327" ], "products": [ "species_351626", "species_2022135", "species_351629", "species_5696178" ], "modifiers": [ [ "species_10076860", "catalyst" ] ], "additional_components": [ "ENSBTAT00000042833" ] }, "reaction_10076884": { "compartment": "compartment_984", "id": "reaction_10076884", "reactome": "R-BTA-5696183", "name": "AOC3 deaminates BZAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_352327", "species_5696148" ], "products": [ "species_351626", "species_5696154", "species_2022135", "species_351629" ], "modifiers": [ [ "species_10076881", "catalyst" ] ], "additional_components": [ "Q9TTK6", "ENSBTAT00000081083", "A0A452DHX8", "ENSBTAT00000001383", "Q29437", "ENSBTAT00000081083", "species_74016", "CHEBI:28694" ] }, "reaction_10076375": { "compartment": "compartment_17957", "id": "reaction_10076375", "reactome": "R-BTA-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_5693702" ], "products": [ "species_156540", "species_5693711", "species_5693712" ], "modifiers": [ [ "species_10076372", "catalyst" ] ], "additional_components": [ "F1MTP2", "ENSBTAT00000032461", "F1MU22", "ENSBTAT00000032343" ] }, "reaction_10086550": { "compartment": "compartment_70101", "id": "reaction_10086550", "reactome": "R-BTA-8937419", "name": "CBR3 reduces DOX to DOXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8937424", "species_29364" ], "products": [ "species_29366", "species_8937418" ], "modifiers": [ [ "species_10086547", "catalyst" ] ], "additional_components": [ "ENSBTAT00000024873" ] }, "reaction_10044524": { "compartment": "compartment_17960", "id": "reaction_10044524", "reactome": "R-BTA-217255", "name": "FMO1:FAD N-oxidises TAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_159154" ], "products": [ "species_113519", "species_113564", "species_217269" ], "modifiers": [ [ "species_10044521", "catalyst" ] ], "additional_components": [ "species_113596", "A0A3Q1M207", "ENSBTAT00000079411" ] }, "reaction_10044533": { "compartment": "compartment_17960", "id": "reaction_10044533", "reactome": "R-BTA-217258", "name": "FMO2:FAD:Mg2+ S-oxidises MTZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113534", "species_156540", "species_113601", "species_217315" ], "products": [ "species_113519", "species_113564", "species_217320" ], "modifiers": [ [ "species_10044530", "catalyst" ] ], "additional_components": [ "species_29926", "species_113596", "G5E540", "ENSBTAT00000003873" ] }, "reaction_10034175": { "compartment": "compartment_70101", "id": "reaction_10034175", "reactome": "R-BTA-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29510", "species_29360" ], "products": [ "species_70106", "species_29416", "species_73473" ], "modifiers": [ [ "species_10034172", "catalyst" ] ], "additional_components": [ "P48644", "ENSBTAT00000010661" ] }, "reaction_10034206": { "compartment": "compartment_70101", "id": "reaction_10034206", "reactome": "R-BTA-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_29510", "species_73473" ], "modifiers": [ [ "species_10034203", "catalyst" ] ], "additional_components": [ "species_29426", "E1BBW9", "ENSBTAT00000020879", "F1MFZ4", "ENSBTAT00000003769", "F1MZN9", "ENSBTAT00000009191", "F1MZP8", "ENSBTAT00000009185" ] }, "reaction_10050160": { "compartment": "compartment_5460", "id": "reaction_10050160", "reactome": "R-BTA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_113539" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10050157", "catalyst" ] ], "additional_components": [ "ENSBTAT00000086374" ] }, "reaction_10076144": { "compartment": "compartment_70101", "id": "reaction_10076144", "reactome": "R-BTA-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_5692249", "species_70106", "species_73473" ], "modifiers": [ [ "species_10076141", "catalyst" ] ], "additional_components": [ "Q3ZC42", "ENSBTAT00000021304", "species_29426" ] }, "reaction_10034215": { "compartment": "compartment_5460", "id": "reaction_10034215", "reactome": "R-BTA-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113532", "species_113526", "species_113521" ], "products": [ "species_113529", "species_29362", "species_113539" ], "modifiers": [ [ "species_10034212", "catalyst" ] ], "additional_components": [ "P20000", "ENSBTAT00000011521" ] }, "reaction_10034231": { "compartment": "compartment_70101", "id": "reaction_10034231", "reactome": "R-BTA-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29416", "species_76194" ], "products": [ "species_111294", "species_76183", "species_76577" ], "modifiers": [ [ "species_10034228", "catalyst" ] ], "additional_components": [ "ENSBTAT00000078990" ] }, "reaction_10075404": { "compartment": "compartment_12045", "id": "reaction_10075404", "reactome": "R-BTA-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5689006" ], "products": [ "species_5689001", "species_5688995" ], "modifiers": [ [ "species_10075401", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015373" ] }, "reaction_10086543": { "compartment": "compartment_7660", "id": "reaction_10086543", "reactome": "R-BTA-8937177", "name": "AHR:TCDD binds ARNT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035973", "species_10035969" ], "products": [ "species_10035975" ], "modifiers": [], "additional_components": [ "ENSBTAT00000016391", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1ML85", "ENSBTAT00000010187", "CHEBI:28119", "F1MYL2", "ENSBTAT00000016391" ] }, "reaction_10086469": { "compartment": "compartment_70101", "id": "reaction_10086469", "reactome": "R-BTA-8936519", "name": "NQO2:FAD dimer reduces quinones to hydroquinones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936516", "species_8936520" ], "products": [ "species_8936514", "species_8936507" ], "modifiers": [ [ "species_10086466", "catalyst" ], [ "species_209934", "inhibitor" ], [ "species_1130942", "inhibitor" ] ], "additional_components": [ "Q3SZT2", "ENSBTAT00000072063", "species_113596" ] }, "reaction_10077734": { "compartment": "compartment_70101", "id": "reaction_10077734", "reactome": "R-BTA-6786190", "name": "CMBL hydrolyses OM to OLMS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_6786175" ], "products": [ "species_6786194", "species_6786179" ], "modifiers": [ [ "species_10077731", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072469" ] }, "reaction_10041241": { "compartment": "compartment_984", "id": "reaction_10041241", "reactome": "R-BTA-192434", "name": "Digestion of diacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_174675" ], "products": [ "species_6814795", "species_174602" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10088973": { "compartment": "compartment_984", "id": "reaction_10088973", "reactome": "R-BTA-8979996", "name": "LIPs hydrolyze TG to DAG and LCFA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10088970", "catalyst" ] ], "additional_components": [] }, "reaction_10041239": { "compartment": "compartment_984", "id": "reaction_10041239", "reactome": "R-BTA-192422", "name": "Digestion of triacylglycerols by extracellular PTL:colipase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171126" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10041236", "catalyst" ] ], "additional_components": [ "A0JNQ7", "ENSBTAT00000022391", "E1BJQ9", "ENSBTAT00000001012" ] }, "reaction_10076274": { "compartment": "compartment_876", "id": "reaction_10076274", "reactome": "R-BTA-5693373", "name": "DDAH1,2 hydrolyses ADMA to DMA and L-Cit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5693375" ], "products": [ "species_5693410", "species_29968" ], "modifiers": [ [ "species_10076271", "catalyst" ] ], "additional_components": [ "P56965", "ENSBTAT00000049235", "Q3SX44", "ENSBTAT00000085909" ] }, "reaction_10040617": { "compartment": "compartment_984", "id": "reaction_10040617", "reactome": "R-BTA-189062", "name": "lactose + H2O => D-glucose + D-galactose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188973", "species_109276" ], "products": [ "species_70115", "species_188995" ], "modifiers": [ [ "species_10040614", "catalyst" ] ], "additional_components": [ "E1BK89", "ENSBTAT00000020185" ] }, "reaction_10040872": { "compartment": "compartment_984", "id": "reaction_10040872", "reactome": "R-BTA-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040620": { "compartment": "compartment_984", "id": "reaction_10040620", "reactome": "R-BTA-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_189049", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040608": { "compartment": "compartment_984", "id": "reaction_10040608", "reactome": "R-BTA-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189108" ], "products": [ "species_191103", "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040595": { "compartment": "compartment_984", "id": "reaction_10040595", "reactome": "R-BTA-188979", "name": "Digestion of linear starch (amylose) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189075" ], "products": [ "species_191103", "species_188986" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10040866": { "compartment": "compartment_984", "id": "reaction_10040866", "reactome": "R-BTA-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_191103" ], "products": [ "species_188986", "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10073378": { "compartment": "compartment_984", "id": "reaction_10073378", "reactome": "R-BTA-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040629": { "compartment": "compartment_984", "id": "reaction_10040629", "reactome": "R-BTA-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040626", "catalyst" ] ], "additional_components": [ "G3N3S2", "ENSBTAT00000064122" ] }, "reaction_10040868": { "compartment": "compartment_984", "id": "reaction_10040868", "reactome": "R-BTA-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188986" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10040605", "catalyst" ] ], "additional_components": [ "E1BGH5", "ENSBTAT00000023366" ] }, "reaction_10040870": { "compartment": "compartment_984", "id": "reaction_10040870", "reactome": "R-BTA-191114", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_189071" ], "products": [ "species_191103", "species_188986", "species_189108" ], "modifiers": [ [ "species_10040592", "catalyst" ] ], "additional_components": [ "species_70113", "F1MJQ3", "ENSBTAT00000082976", "F1MP21", "ENSBTAT00000060970", "A0A3Q1LQY4", "ENSBTAT00000083621" ] }, "reaction_10086435": { "compartment": "compartment_984", "id": "reaction_10086435", "reactome": "R-BTA-8936214", "name": "GUCY2C trimer binds GUCA2A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10086431", "species_10086425" ], "products": [ "species_10086433" ], "modifiers": [], "additional_components": [ "F1N5B2", "ENSBTAT00000026286", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "E1BIM0", "ENSBTAT00000009466", "E1BIM1", "ENSBTAT00000009465", "F1N5B2", "ENSBTAT00000026286" ] }, "reaction_10036917": { "compartment": "compartment_7660", "id": "reaction_10036917", "reactome": "R-BTA-111438", "name": "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036044", "species_10036072" ], "products": [ "species_10036911" ], "modifiers": [], "additional_components": [ "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "A0A3Q1MM18", "ENSBTAT00000086549", "A0A3Q1LW50", "ENSBTAT00000076380", "E1BHK8", "ENSBTAT00000076380", "F1N150", "ENSBTAT00000076380", "Q3T0Z8", "ENSBTAT00000021643", "A4IFN1", "ENSBTAT00000033237", "Q3ZBL0", "ENSBTAT00000007241", "F1MKH0", "ENSBTAT00000013683", "A0A3Q1M973", "ENSBTAT00000001380", "F1N038", "ENSBTAT00000016000", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10039865": { "compartment": "compartment_70101", "id": "reaction_10039865", "reactome": "R-BTA-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_111707", "species_113592" ], "products": [ "species_29372", "species_174393", "species_29370" ], "modifiers": [ [ "species_10039862", "catalyst" ] ], "additional_components": [ "A0A3Q1MN33", "ENSBTAT00000081594", "Q2T9Y6", "ENSBTAT00000026855" ] }, "reaction_10087515": { "compartment": "compartment_876", "id": "reaction_10087515", "reactome": "R-BTA-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1247892" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10077658": { "compartment": "compartment_70101", "id": "reaction_10077658", "reactome": "R-BTA-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247942", "species_1247904" ], "modifiers": [ [ "species_10077655", "catalyst" ] ], "additional_components": [ "A6H738", "ENSBTAT00000013689", "Q0IIH4", "ENSBTAT00000025922" ] }, "reaction_10057079": { "compartment": "compartment_70101", "id": "reaction_10057079", "reactome": "R-BTA-1247922", "name": "GGCT transforms gGluCys to OPRO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174393" ], "products": [ "species_111707", "species_1247942" ], "modifiers": [ [ "species_10057076", "catalyst" ] ], "additional_components": [ "Q32LE4", "ENSBTAT00000014010" ] }, "reaction_10075362": { "compartment": "compartment_17927", "id": "reaction_10075362", "reactome": "R-BTA-5688294", "name": "SIRT5 deacetylates Cytochrome C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688282", "species_10075353" ], "products": [ "species_5688281", "species_10037239", "species_5688340" ], "modifiers": [ [ "species_10075359", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007918", "ENSBTAT00000007918", "Q3ZBQ0", "ENSBTAT00000072664", "species_29426" ] }, "reaction_10075350": { "compartment": "compartment_5460", "id": "reaction_10075350", "reactome": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10075337" ], "products": [ "species_5688337", "species_5688274", "species_10075341" ], "modifiers": [ [ "species_10075347", "catalyst" ] ], "additional_components": [ "A0A3Q1MB37", "ENSBTAT00000078990", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "Q04467", "ENSBTAT00000018741", "E1BHL1", "ENSBTAT00000008569", "A0A3Q1MB37", "ENSBTAT00000078990", "G5E521", "ENSBTAT00000002648", "species_29426" ] }, "reaction_10072271": { "compartment": "compartment_20699", "id": "reaction_10072271", "reactome": "R-BTA-5617828", "name": "TRIP11:IFT20 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10072269" ], "products": [ "species_10072263", "species_10072267" ], "modifiers": [], "additional_components": [ "A0A3Q1MQ84", "ENSBTAT00000084706", "Q58CS6", "ENSBTAT00000084852", "ENSBTAT00000084852", "ENSBTAT00000084706" ] }, "reaction_10058751": { "compartment": "compartment_70101", "id": "reaction_10058751", "reactome": "R-BTA-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111627" ], "products": [ "species_29356", "species_113528" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058753": { "compartment": "compartment_876", "id": "reaction_10058753", "reactome": "R-BTA-1475025", "name": "Carbonic anhydrase hydrates carbon dioxide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_1237009" ], "products": [ "species_351626", "species_425425" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058755": { "compartment": "compartment_70101", "id": "reaction_10058755", "reactome": "R-BTA-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113528" ], "products": [ "species_70106", "species_111627" ], "modifiers": [ [ "species_10058748", "catalyst" ] ], "additional_components": [ "species_29426", "Q1LZA1", "ENSBTAT00000045723", "A0A3Q1MAE5", "ENSBTAT00000071702", "F1N0H3", "ENSBTAT00000023581", "Q3SZX4", "ENSBTAT00000020243" ] }, "reaction_10058722": { "compartment": "compartment_876", "id": "reaction_10058722", "reactome": "R-BTA-1475017", "name": "Carbonic anhydrase dehydrates bicarbonate (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351626", "species_425425" ], "products": [ "species_109276", "species_1237009" ], "modifiers": [ [ "species_10058719", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MI50", "ENSBTAT00000067395", "E1BPA4", "ENSBTAT00000015174" ] }, "reaction_10058772": { "compartment": "compartment_5460", "id": "reaction_10058772", "reactome": "R-BTA-1475028", "name": "Carbonic anhydrase dehydrates bicarbonate (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29896", "species_113529" ], "products": [ "species_113521", "species_29376" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10058774": { "compartment": "compartment_5460", "id": "reaction_10058774", "reactome": "R-BTA-1475032", "name": "Carbonic anhydrase hydrates carbon dioxide (mitochondria)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_29376" ], "products": [ "species_29896", "species_113529" ], "modifiers": [ [ "species_10058769", "catalyst" ] ], "additional_components": [ "A0A3Q1LWK4", "ENSBTAT00000068215", "species_29426", "F1N5D1", "ENSBTAT00000027210" ] }, "reaction_10040030": { "compartment": "compartment_17957", "id": "reaction_10040030", "reactome": "R-BTA-176059", "name": "GST trimers transfer GS from GSH to luminal substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_158543", "species_176065" ], "products": [ "species_176048" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_38987", "CHEBI:29132", "CHEBI:32639", "CHEBI:2505", "CHEBI:35896", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10067425": { "compartment": "compartment_5460", "id": "reaction_10067425", "reactome": "R-BTA-3301943", "name": "GSTK1 dimer transfers GS from GSH to CDNB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1655887", "species_3301954" ], "products": [ "species_3301973", "species_3301969" ], "modifiers": [ [ "species_10067422", "catalyst" ] ], "additional_components": [ "F1MRG0", "ENSBTAT00000012969" ] }, "reaction_10040021": { "compartment": "compartment_70101", "id": "reaction_10040021", "reactome": "R-BTA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_176070" ], "products": [ "species_176049" ], "modifiers": [ [ "species_10040018", "catalyst" ] ], "additional_components": [ "CHEBI:29132", "species_3301954", "CHEBI:30614", "species_3301969", "CHEBI:32639", "CHEBI:34479", "A0A3Q1LMV5", "ENSBTAT00000084460", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "F1MUX5", "ENSBTAT00000016866", "A0A3Q1LY34", "ENSBTAT00000075425", "E1BJ08", "ENSBTAT00000017435", "Q2NL00", "ENSBTAT00000007403", "A1A4L7", "ENSBTAT00000021896", "A0A3Q1MEZ2", "ENSBTAT00000075831", "A0A3Q1LSN6", "ENSBTAT00000085178", "E1BED9", "ENSBTAT00000005211", "F1MGZ9", "ENSBTAT00000022700" ] }, "reaction_10076133": { "compartment": "compartment_70101", "id": "reaction_10076133", "reactome": "R-BTA-5692232", "name": "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_5692212" ], "products": [ "species_5692216", "species_29364" ], "modifiers": [ [ "species_10073435", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000630" ] }, "reaction_10040185": { "compartment": "compartment_5460", "id": "reaction_10040185", "reactome": "R-BTA-177157", "name": "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113593", "species_177153" ], "products": [ "species_159448", "species_159450", "species_177137" ], "modifiers": [ [ "species_10038351", "catalyst" ] ], "additional_components": [ "ENSBTAT00000025874" ] }, "reaction_10038316": { "compartment": "compartment_70101", "id": "reaction_10038316", "reactome": "R-BTA-158832", "name": "The acetyl group from acetyl-CoA is transferred to the NAT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039918": { "compartment": "compartment_70101", "id": "reaction_10039918", "reactome": "R-BTA-174959", "name": "The acetyl group from acetyl-CoA is transferred to the NAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10038311", "species_76183" ], "products": [ "species_76194", "species_10038314" ], "modifiers": [], "additional_components": [ "ENSBTAT00000048506", "ENSBTAT00000048506" ] }, "reaction_10039921": { "compartment": "compartment_70101", "id": "reaction_10039921", "reactome": "R-BTA-174963", "name": "NAT1 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174969", "species_10038314" ], "products": [ "species_10038311", "species_174960" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:45373", "CHEBI:30753", "species_34889", "CHEBI:27565", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:63845", "CHEBI:16395", "CHEBI:63815", "CHEBI:63817", "ENSBTAT00000048506" ] }, "reaction_10039923": { "compartment": "compartment_70101", "id": "reaction_10039923", "reactome": "R-BTA-174967", "name": "NAT2 acetylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174971", "species_10038314" ], "products": [ "species_10038311", "species_174958" ], "modifiers": [ [ "species_10038314", "catalyst" ] ], "additional_components": [ "CHEBI:6030", "species_76424", "species_34889", "ENSBTAT00000048506", "ENSBTAT00000048506", "CHEBI:7207", "CHEBI:32643", "CHEBI:16395", "ENSBTAT00000048506" ] }, "reaction_10071722": { "compartment": "compartment_70101", "id": "reaction_10071722", "reactome": "R-BTA-5423664", "name": "CYP3A4,5 hydroxylates AFB1 to AFQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423660", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071719", "catalyst" ] ], "additional_components": [ "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071754": { "compartment": "compartment_984", "id": "reaction_10071754", "reactome": "R-BTA-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10071751", "catalyst" ] ], "additional_components": [ "CHEBI:78581", "CHEBI:78587", "CHEBI:78579", "CHEBI:78584", "G3N2D8", "ENSBTAT00000063999" ] }, "reaction_10038060": { "compartment": "compartment_70101", "id": "reaction_10038060", "reactome": "R-BTA-156526", "name": "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_29356", "species_159211", "species_29366" ], "modifiers": [ [ "species_10038057", "catalyst" ] ], "additional_components": [ "G3MYH2", "ENSBTAT00000065779", "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177", "A0A3Q1LZ03", "ENSBTAT00000067793", "Q29RV2", "ENSBTAT00000016177", "Q3T047", "ENSBTAT00000063483" ] }, "reaction_10071727": { "compartment": "compartment_70101", "id": "reaction_10071727", "reactome": "R-BTA-5423672", "name": "CYP1A2, 3A4 oxidise AFB1 to AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423663", "species_29356", "species_29366" ], "modifiers": [ [ "species_10071724", "catalyst" ] ], "additional_components": [ "F1MHN9", "ENSBTAT00000000094", "G3X6I4", "ENSBTAT00000016177" ] }, "reaction_10071729": { "compartment": "compartment_12045", "id": "reaction_10071729", "reactome": "R-BTA-5423678", "name": "CYP1A2 hydroxylates AFB1 to AFM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29368", "species_5423605", "species_29364" ], "products": [ "species_5423629", "species_29356", "species_29366" ], "modifiers": [ [ "species_10035858", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000094" ] }, "reaction_10071712": { "compartment": "compartment_70101", "id": "reaction_10071712", "reactome": "R-BTA-5423637", "name": "AKR dimers reduce AFBDHO to AFBDOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423727", "species_70106", "species_29364" ], "products": [ "species_29366", "species_5423729" ], "modifiers": [ [ "species_10071709", "catalyst" ] ], "additional_components": [ "F1MZC0", "ENSBTAT00000016300", "F1N6I4", "ENSBTAT00000038217" ] }, "reaction_10071715": { "compartment": "compartment_70101", "id": "reaction_10071715", "reactome": "R-BTA-5423647", "name": "CYP2A13 oxidises AFM1 to AFM1E", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5423629", "species_70106", "species_29368", "species_29364" ], "products": [ "species_29356", "species_5423657", "species_29366" ], "modifiers": [ [ "species_10035869", "catalyst" ] ], "additional_components": [ "ENSBTAT00000065779" ] }, "reaction_10071763": { "compartment": "compartment_70101", "id": "reaction_10071763", "reactome": "R-BTA-5433074", "name": "ACY1:Zn2+ dimer hydrolyses mercapturic acids", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490236", "species_29356" ], "products": [ "species_2022890", "species_5490231" ], "modifiers": [ [ "species_10071760", "catalyst" ] ], "additional_components": [ "CHEBI:78580", "CHEBI:78585", "CHEBI:78583", "CHEBI:78578", "species_29426", "F1MR63", "ENSBTAT00000024787" ] }, "reaction_10071717": { "compartment": "compartment_70101", "id": "reaction_10071717", "reactome": "R-BTA-5423653", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5423723" ], "products": [ "species_5423730" ], "modifiers": [ [ "species_10040027", "catalyst" ] ], "additional_components": [ "species_159211", "species_5423663", "CHEBI:78581", "CHEBI:78587", "Q2KJG4", "ENSBTAT00000029028" ] }, "reaction_10074761": { "compartment": "compartment_70101", "id": "reaction_10074761", "reactome": "R-BTA-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074753", "species_10074751" ], "products": [ "species_10074755" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "ENSBTAT00000016216", "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035720": { "compartment": "compartment_7660", "id": "reaction_10035720", "reactome": "R-BTA-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035716", "species_10035710" ], "products": [ "species_10035718" ], "modifiers": [], "additional_components": [ "ENSBTAT00000017598", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10035712": { "compartment": "compartment_7660", "id": "reaction_10035712", "reactome": "R-BTA-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035708", "species_10035704" ], "products": [ "species_10035710" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011748", "ENSBTAT00000014945", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748" ] }, "reaction_10074759": { "compartment": "compartment_7660", "id": "reaction_10074759", "reactome": "R-BTA-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074755" ], "products": [ "species_10035716", "species_10074757" ], "modifiers": [], "additional_components": [ "Q3SYV6", "ENSBTAT00000016216", "F6PSE2", "ENSBTAT00000017598", "ENSBTAT00000017598", "ENSBTAT00000016216" ] }, "reaction_10074747": { "compartment": "compartment_7660", "id": "reaction_10074747", "reactome": "R-BTA-5683986", "name": "APBB1 and MAPK8 bind diphosphorylated H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074743", "species_10074733", "species_10039497" ], "products": [ "species_10074745" ], "modifiers": [], "additional_components": [ "ENSBTAT00000069360", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "ENSBTAT00000087439", "A0A3Q1LWJ8", "ENSBTAT00000087439", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "A0A3Q1MU04", "ENSBTAT00000069360" ] }, "reaction_10074558": { "compartment": "compartment_7660", "id": "reaction_10074558", "reactome": "R-BTA-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074548" ], "products": [ "species_113582", "species_10074555" ], "modifiers": [ [ "species_10074548", "catalyst" ] ], "additional_components": [ "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10074736": { "compartment": "compartment_7660", "id": "reaction_10074736", "reactome": "R-BTA-5683964", "name": "ATM phosphorylates EYA1-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074724" ], "products": [ "species_113582", "species_10074727" ], "modifiers": [ [ "species_10074733", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074020", "ENSBTAT00000074020", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074739": { "compartment": "compartment_7660", "id": "reaction_10074739", "reactome": "R-BTA-5683967", "name": "EYA1-4 dephosphorylates tyrosine Y142 of H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10074733" ], "products": [ "species_113550", "species_10074663" ], "modifiers": [ [ "species_10074727", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "ENSBTAT00000074020" ] }, "reaction_10074677": { "compartment": "compartment_7660", "id": "reaction_10074677", "reactome": "R-BTA-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074674" ], "products": [ "species_113582", "species_10074667" ], "modifiers": [ [ "species_10074674", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074679": { "compartment": "compartment_7660", "id": "reaction_10074679", "reactome": "R-BTA-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069716", "species_10074542" ], "products": [ "species_10074544" ], "modifiers": [], "additional_components": [ "ENSBTAT00000002687", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687" ] }, "reaction_10074550": { "compartment": "compartment_7660", "id": "reaction_10074550", "reactome": "R-BTA-5682586", "name": "HERC2 and PIAS4 are recruited to DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10069303", "species_10074546", "species_10069553" ], "products": [ "species_10074548" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001000", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "ENSBTAT00000018496", "E1B782", "ENSBTAT00000018496", "species_29426", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BPL5", "ENSBTAT00000002687", "A4FV15", "ENSBTAT00000001000" ] }, "reaction_10076329": { "compartment": "compartment_7660", "id": "reaction_10076329", "reactome": "R-BTA-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074663", "species_10076288" ], "products": [ "species_10076290" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10076332": { "compartment": "compartment_7660", "id": "reaction_10076332", "reactome": "R-BTA-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076295", "species_29358" ], "products": [ "species_113582", "species_10074530" ], "modifiers": [ [ "species_10076295", "catalyst" ] ], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BEI6", "ENSBTAT00000040104", "A0A3Q1MIR9", "ENSBTAT00000083355", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598" ] }, "reaction_10076303": { "compartment": "compartment_7660", "id": "reaction_10076303", "reactome": "R-BTA-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076300" ], "products": [ "species_113582", "species_10074733" ], "modifiers": [ [ "species_10076300", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10076334": { "compartment": "compartment_7660", "id": "reaction_10076334", "reactome": "R-BTA-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074530", "species_10074715" ], "products": [ "species_10076300" ], "modifiers": [], "additional_components": [ "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355" ] }, "reaction_10074670": { "compartment": "compartment_7660", "id": "reaction_10074670", "reactome": "R-BTA-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10074667" ], "products": [ "species_77502", "species_10074542" ], "modifiers": [ [ "species_10074667", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "A0A3Q1LMV7", "ENSBTAT00000085055", "P62803", "ENSBTAT00000072717", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10074720": { "compartment": "compartment_7660", "id": "reaction_10074720", "reactome": "R-BTA-5683930", "name": "WICH phosphorylates H2AFX on Y142", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10074711" ], "products": [ "species_113582", "species_10074715" ], "modifiers": [ [ "species_10074717", "catalyst" ] ], "additional_components": [ "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1B6X6", "ENSBTAT00000072070", "A0A3Q1M384", "ENSBTAT00000070441" ] }, "reaction_10076293": { "compartment": "compartment_7660", "id": "reaction_10076293", "reactome": "R-BTA-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076290" ], "products": [ "species_113582", "species_10074665" ], "modifiers": [ [ "species_10076290", "catalyst" ] ], "additional_components": [ "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055", "E1BI26", "ENSBTAT00000035900", "E1BEI6", "ENSBTAT00000040104", "G3X6W2", "ENSBTAT00000014945", "E1BIN9", "ENSBTAT00000011748", "F6PSE2", "ENSBTAT00000017598", "A0A3Q1MIR9", "ENSBTAT00000083355", "E1BGN3", "ENSBTAT00000033058", "P62803", "ENSBTAT00000072717", "A0A3Q1LMV7", "ENSBTAT00000085055" ] }, "reaction_10075173": { "compartment": "compartment_7660", "id": "reaction_10075173", "reactome": "R-BTA-5686578", "name": "Activated ATM phosphorylates ABL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075167" ], "products": [ "species_113582", "species_10075170" ], "modifiers": [ [ "species_10074441", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080797", "ENSBTAT00000080797", "ENSBTAT00000040104" ] }, "reaction_10049230": { "compartment": "compartment_70101", "id": "reaction_10049230", "reactome": "R-BTA-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_429926" ], "products": [ "species_430042", "species_429925" ], "modifiers": [ [ "species_10049227", "catalyst" ] ], "additional_components": [ "ENSBTAT00000003732" ] }, "reaction_10049232": { "compartment": "compartment_70101", "id": "reaction_10049232", "reactome": "R-BTA-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10049219", "species_429974" ], "products": [ "species_10049221" ], "modifiers": [], "additional_components": [ "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566", "A6QQV3", "ENSBTAT00000007405", "A0A452DIA6", "ENSBTAT00000009684", "F1N6T3", "ENSBTAT00000005939", "A0A3Q1M2U2", "ENSBTAT00000069947", "A0A3Q1LMH1", "ENSBTAT00000072254", "A0A3Q1LRX5", "ENSBTAT00000077566" ] }, "reaction_10061043": { "compartment": "compartment_17957", "id": "reaction_10061043", "reactome": "R-BTA-1855200", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024002" ], "products": [ "species_113551", "species_2024016" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10060963": { "compartment": "compartment_17957", "id": "reaction_10060963", "reactome": "R-BTA-1855163", "name": "I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024008" ], "products": [ "species_113551", "species_2024012" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10061122": { "compartment": "compartment_17957", "id": "reaction_10061122", "reactome": "R-BTA-1855225", "name": "IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113519", "species_2024018" ], "products": [ "species_113551", "species_2564836" ], "modifiers": [ [ "species_10060960", "catalyst" ] ], "additional_components": [ "ENSBTAT00000007784" ] }, "reaction_10036907": { "compartment": "compartment_70101", "id": "reaction_10036907", "reactome": "R-BTA-111285", "name": "Formation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10035351" ], "products": [ "species_10036905" ], "modifiers": [ [ "species_113578", "catalyst" ], [ "species_29602", "catalyst" ], [ "species_76577", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035339": { "compartment": "compartment_70101", "id": "reaction_10035339", "reactome": "R-BTA-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_29372", "species_111370", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035354": { "compartment": "compartment_70101", "id": "reaction_10035354", "reactome": "R-BTA-73815", "name": "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_29356", "species_29472" ], "products": [ "species_111294", "species_111292", "species_29404" ], "modifiers": [ [ "species_10035351", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10036909": { "compartment": "compartment_70101", "id": "reaction_10036909", "reactome": "R-BTA-111289", "name": "Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036905" ], "products": [ "species_10035351" ], "modifiers": [ [ "species_73566", "catalyst" ] ], "additional_components": [ "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667", "CHEBI:17909", "species_71067", "F1MV22", "ENSBTAT00000052667" ] }, "reaction_10035308": { "compartment": "compartment_70101", "id": "reaction_10035308", "reactome": "R-BTA-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_111584", "species_29472" ], "products": [ "species_111294", "species_29404", "species_113578", "species_76577" ], "modifiers": [ [ "species_10035305", "catalyst" ] ], "additional_components": [ "ENSBTAT00000084984" ] }, "reaction_10091727": { "compartment": "compartment_70101", "id": "reaction_10091727", "reactome": "R-BTA-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9678719", "species_10035314" ], "products": [ "species_10035317" ], "modifiers": [], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10035342": { "compartment": "compartment_70101", "id": "reaction_10035342", "reactome": "R-BTA-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_111354", "species_111355" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035345": { "compartment": "compartment_70101", "id": "reaction_10035345", "reactome": "R-BTA-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111292", "species_113592", "species_29424" ], "products": [ "species_29372", "species_111338", "species_29370" ], "modifiers": [ [ "species_10035336", "catalyst" ] ], "additional_components": [ "ENSBTAT00000012108" ] }, "reaction_10035329": { "compartment": "compartment_70101", "id": "reaction_10035329", "reactome": "R-BTA-73805", "name": "CAIR + Aspartate + ATP => SAICAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29448", "species_111395" ], "products": [ "species_29372", "species_29370", "species_111399" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10036928": { "compartment": "compartment_70101", "id": "reaction_10036928", "reactome": "R-BTA-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29448", "species_29602" ], "products": [ "species_29372", "species_29420", "species_35141" ], "modifiers": [ [ "species_10036925", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_30014", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_113578", "inhibitor" ] ], "additional_components": [ "A7MBG0", "ENSBTAT00000047061", "species_29926" ] }, "reaction_10035332": { "compartment": "compartment_70101", "id": "reaction_10035332", "reactome": "R-BTA-73806", "name": "AIR + CO2 => CAIR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111370", "species_113528" ], "products": [ "species_111395" ], "modifiers": [ [ "species_10035326", "catalyst" ] ], "additional_components": [ "F1MN04", "ENSBTAT00000013985" ] }, "reaction_10035319": { "compartment": "compartment_70101", "id": "reaction_10035319", "reactome": "R-BTA-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_29602", "species_29360" ], "products": [ "species_70106", "species_111584", "species_73473" ], "modifiers": [ [ "species_10035314", "catalyst" ], [ "species_111584", "inhibitor" ], [ "species_10035317", "inhibitor" ] ], "additional_components": [ "Q3SWY3", "ENSBTAT00000025179", "Q3SWY3", "ENSBTAT00000025179" ] }, "reaction_10076312": { "compartment": "compartment_7660", "id": "reaction_10076312", "reactome": "R-BTA-5693575", "name": "DNA-PKcs autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10076309" ], "products": [ "species_113582", "species_10075286" ], "modifiers": [ [ "species_10076309", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076347": { "compartment": "compartment_7660", "id": "reaction_10076347", "reactome": "R-BTA-5693615", "name": "Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076305", "species_10076345" ], "products": [ "species_10076309" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10075295": { "compartment": "compartment_7660", "id": "reaction_10075295", "reactome": "R-BTA-5687183", "name": "PRKDC phosphorylates DCLRE1C at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10075288" ], "products": [ "species_113582", "species_10075292" ], "modifiers": [ [ "species_10075288", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076286": { "compartment": "compartment_7660", "id": "reaction_10076286", "reactome": "R-BTA-5693533", "name": "DCLRE1C (ARTEMIS) processes DNA DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10075292" ], "products": [ "species_10076283" ], "modifiers": [ [ "species_10075292", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10076327": { "compartment": "compartment_7660", "id": "reaction_10076327", "reactome": "R-BTA-5693578", "name": "TDP1 and TDP2 process unligatable DSB ends", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076283" ], "products": [ "species_10076314" ], "modifiers": [ [ "species_10076324", "catalyst" ] ], "additional_components": [ "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631", "A7MBA7", "ENSBTAT00000013758", "F1MMD5", "ENSBTAT00000008020", "E1BLB6", "ENSBTAT00000022631" ] }, "reaction_10036649": { "compartment": "compartment_70101", "id": "reaction_10036649", "reactome": "R-BTA-109903", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10036646", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A3Q1LZ00", "ENSBTAT00000077740" ] }, "reaction_10034989": { "compartment": "compartment_70101", "id": "reaction_10034989", "reactome": "R-BTA-73599", "name": "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10034986", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "A0A452DII0", "ENSBTAT00000014316" ] }, "reaction_10035020": { "compartment": "compartment_70101", "id": "reaction_10035020", "reactome": "R-BTA-73632", "name": "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_83928" ], "products": [ "species_29370", "species_109366" ], "modifiers": [ [ "species_10035017", "catalyst" ] ], "additional_components": [ "A0A3Q1NEX0", "ENSBTAT00000073714" ] }, "reaction_10035007": { "compartment": "compartment_70101", "id": "reaction_10035007", "reactome": "R-BTA-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500829" ], "products": [ "species_500430", "species_31633" ], "modifiers": [ [ "species_10035004", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "CHEBI:16450", "CHEBI:16704", "species_29426", "A0A3Q1MGS0", "ENSBTAT00000074118" ] }, "reaction_10088624": { "compartment": "compartment_70101", "id": "reaction_10088624", "reactome": "R-BTA-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_500759" ], "products": [ "species_500761", "species_29370" ], "modifiers": [ [ "species_10088621", "catalyst" ] ], "additional_components": [ "CHEBI:16704", "CHEBI:17562", "species_727810", "species_109402", "ENSBTAT00000071389" ] }, "reaction_10034980": { "compartment": "compartment_70101", "id": "reaction_10034980", "reactome": "R-BTA-73598", "name": "(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_113592" ], "products": [ "species_500828", "species_29370" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:15698", "CHEBI:17562", "species_727810", "species_109378", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035479": { "compartment": "compartment_70101", "id": "reaction_10035479", "reactome": "R-BTA-74372", "name": "uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83962", "species_500244" ], "products": [ "species_29372", "species_500430" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:28542", "species_112016", "CHEBI:16450", "CHEBI:16704", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10036614": { "compartment": "compartment_5460", "id": "reaction_10036614", "reactome": "R-BTA-109759", "name": "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500822" ], "products": [ "species_113581", "species_500823" ], "modifiers": [ [ "species_10036611", "catalyst" ] ], "additional_components": [ "species_83928", "CHEBI:16450", "CHEBI:15698", "species_109366", "species_500742", "species_109378", "ENSBTAT00000064369" ] }, "reaction_10069313": { "compartment": "compartment_984", "id": "reaction_10069313", "reactome": "R-BTA-4084505", "name": "Laminins bind HSPG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059693", "species_10069309" ], "products": [ "species_10069311" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022744", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "F1MER7", "ENSBTAT00000022744" ] }, "reaction_10044515": { "compartment": "compartment_984", "id": "reaction_10044515", "reactome": "R-BTA-216048", "name": "Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044511", "species_10044490" ], "products": [ "species_10044513" ], "modifiers": [], "additional_components": [ "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126", "A0A3Q1MRM3", "ENSBTAT00000075471", "A0A3Q1M8K4", "ENSBTAT00000085126" ] }, "reaction_10065555": { "compartment": "compartment_984", "id": "reaction_10065555", "reactome": "R-BTA-2426450", "name": "Laminins:Nidogens binds collagen type IV networks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10059526", "species_10065551" ], "products": [ "species_10065553" ], "modifiers": [], "additional_components": [ "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1MY30", "ENSBTAT00000082437", "A0A3Q1N3A0", "ENSBTAT00000073403", "F1N0T1", "ENSBTAT00000023245", "E1BDK6", "ENSBTAT00000057452", "F1MD77", "ENSBTAT00000015881", "A0A3Q1N9E9", "ENSBTAT00000069112", "F1MDD5", "ENSBTAT00000060991", "A6QNS6", "ENSBTAT00000009531", "A0A3Q1LLV2", "ENSBTAT00000083510", "A0A3Q1NK51", "ENSBTAT00000083333", "A0A3Q1M970", "ENSBTAT00000070553" ] }, "reaction_10047065": { "compartment": "compartment_17951", "id": "reaction_10047065", "reactome": "R-BTA-390438", "name": "FAR2 reduces PalmCoA to HXOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200993" ], "products": [ "species_29366", "species_8848577", "species_76194" ], "modifiers": [ [ "species_10047062", "catalyst" ] ], "additional_components": [ "ENSBTAT00000014725" ] }, "reaction_10083577": { "compartment": "compartment_12045", "id": "reaction_10083577", "reactome": "R-BTA-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_30209" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10083575": { "compartment": "compartment_12045", "id": "reaction_10083575", "reactome": "R-BTA-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_8848499", "species_76194" ], "modifiers": [ [ "species_10065670", "catalyst" ] ], "additional_components": [ "ENSBTAT00000074877" ] }, "reaction_10091611": { "compartment": "compartment_70101", "id": "reaction_10091611", "reactome": "R-BTA-9663492", "name": "BIL dissociates from GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091609" ], "products": [ "species_10091607", "species_189386" ], "modifiers": [], "additional_components": [ "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091613": { "compartment": "compartment_70101", "id": "reaction_10091613", "reactome": "R-BTA-9663511", "name": "BIL binds GSTA1, FABP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10091607", "species_189386" ], "products": [ "species_10091609" ], "modifiers": [], "additional_components": [ "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032", "species_159151", "E1BKD8", "ENSBTAT00000035828", "F1MX44", "ENSBTAT00000035828", "O18879", "ENSBTAT00000046354", "P80425", "ENSBTAT00000024032" ] }, "reaction_10091598": { "compartment": "compartment_70101", "id": "reaction_10091598", "reactome": "R-BTA-9661397", "name": "SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10051847", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10091605": { "compartment": "compartment_70101", "id": "reaction_10091605", "reactome": "R-BTA-9661799", "name": "SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9661418" ], "products": [ "species_189386" ], "modifiers": [ [ "species_10091602", "catalyst" ] ], "additional_components": [ "ENSBTAT00000030217" ] }, "reaction_10069412": { "compartment": "compartment_876", "id": "reaction_10069412", "reactome": "R-BTA-4088281", "name": "Endorepellin binds KDR (VEGFR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10041457", "species_10068872" ], "products": [ "species_10069410" ], "modifiers": [], "additional_components": [ "ENSBTAT00000001038", "ENSBTAT00000022744", "F1MER7", "ENSBTAT00000022744", "F1MWF1", "ENSBTAT00000001038" ] }, "reaction_10074474": { "compartment": "compartment_12045", "id": "reaction_10074474", "reactome": "R-BTA-5682084", "name": "ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200993", "species_10074459" ], "products": [ "species_10074467", "species_76194" ], "modifiers": [ [ "species_10074471", "catalyst" ] ], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538", "ENSBTAT00000006197" ] }, "reaction_10074486": { "compartment": "compartment_12045", "id": "reaction_10074486", "reactome": "R-BTA-5682103", "name": "4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10074467" ], "products": [ "species_10074478" ], "modifiers": [], "additional_components": [ "F1MG24", "ENSBTAT00000027538", "F1MG24", "ENSBTAT00000027538" ] }, "reaction_10076091": { "compartment": "compartment_70101", "id": "reaction_10076091", "reactome": "R-BTA-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076087", "species_10039822" ], "products": [ "species_10076089" ], "modifiers": [], "additional_components": [ "ENSBTAT00000013112", "ENSBTAT00000068449", "F1MYD0", "ENSBTAT00000068449", "A7MBJ5", "ENSBTAT00000013112" ] }, "reaction_10059181": { "compartment": "compartment_70101", "id": "reaction_10059181", "reactome": "R-BTA-1562626", "name": "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_71067", "species_29368" ], "products": [ "species_5691103" ], "modifiers": [ [ "species_10059178", "catalyst" ] ], "additional_components": [ "A0A3Q1MNC0", "ENSBTAT00000034356", "A0A3Q1NGZ9", "ENSBTAT00000034356", "F1MUL1", "ENSBTAT00000034356", "O46415", "ENSBTAT00000009965" ] }, "reaction_10076083": { "compartment": "compartment_70101", "id": "reaction_10076083", "reactome": "R-BTA-5691108", "name": "SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10076005", "species_10033408" ], "products": [ "species_10076074" ], "modifiers": [ [ "species_10076080", "catalyst" ] ], "additional_components": [ "ENSBTAT00000077304", "P63048", "ENSBTAT00000010176", "A0A3Q1LU30", "ENSBTAT00000087088", "P0CG53", "ENSBTAT00000022919", "ENSBTAT00000077304", "E1BJ64", "ENSBTAT00000028591", "Q3ZCF3", "ENSBTAT00000035306", "F1MYD0", "ENSBTAT00000068449" ] }, "reaction_10052866": { "compartment": "compartment_984", "id": "reaction_10052866", "reactome": "R-BTA-917805", "name": "CYBRD1:Heme reduces Fe3+ to Fe2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_917828", "species_912516" ], "products": [ "species_435347" ], "modifiers": [ [ "species_10052863", "catalyst" ] ], "additional_components": [ "species_71185", "F1MLZ1", "ENSBTAT00000010387" ] }, "reaction_10052916": { "compartment": "compartment_984", "id": "reaction_10052916", "reactome": "R-BTA-917888", "name": "apoTF binds 2Fe3+ to form holoTF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_912516", "species_10051000" ], "products": [ "species_10052874" ], "modifiers": [], "additional_components": [ "ENSBTAT00000009564", "G3X6N3", "ENSBTAT00000009564", "species_917966" ] }, "reaction_10087646": { "compartment": "compartment_70616", "id": "reaction_10087646", "reactome": "R-BTA-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2889072", "species_8949220" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10087643", "catalyst" ] ], "additional_components": [ "ENSBTAT00000070502" ] }, "reaction_10061116": { "compartment": "compartment_70101", "id": "reaction_10061116", "reactome": "R-BTA-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10060956": { "compartment": "compartment_70101", "id": "reaction_10060956", "reactome": "R-BTA-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061040": { "compartment": "compartment_70101", "id": "reaction_10061040", "reactome": "R-BTA-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061011": { "compartment": "compartment_70101", "id": "reaction_10061011", "reactome": "R-BTA-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10061008", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015737" ] }, "reaction_10060980": { "compartment": "compartment_70101", "id": "reaction_10060980", "reactome": "R-BTA-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10060983": { "compartment": "compartment_70101", "id": "reaction_10060983", "reactome": "R-BTA-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023943" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10060969", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797" ] }, "reaction_10061079": { "compartment": "compartment_70101", "id": "reaction_10061079", "reactome": "R-BTA-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061034": { "compartment": "compartment_70101", "id": "reaction_10061034", "reactome": "R-BTA-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063018": { "compartment": "compartment_70101", "id": "reaction_10063018", "reactome": "R-BTA-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2023974" ], "products": [ "species_29372", "species_1629770" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061037": { "compartment": "compartment_70101", "id": "reaction_10061037", "reactome": "R-BTA-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10063020": { "compartment": "compartment_70101", "id": "reaction_10063020", "reactome": "R-BTA-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_29372", "species_2023974" ], "modifiers": [ [ "species_10060977", "catalyst" ] ], "additional_components": [ "species_1629732", "CHEBI:62924", "species_1629740", "CHEBI:62922", "species_29926", "species_113527", "A2VDV0", "ENSBTAT00000009797", "A7MBH2", "ENSBTAT00000085197" ] }, "reaction_10061024": { "compartment": "compartment_70101", "id": "reaction_10061024", "reactome": "R-BTA-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_1629732", "species_29370" ], "modifiers": [ [ "species_10061021", "catalyst" ] ], "additional_components": [ "ENSBTAT00000072742" ] }, "reaction_10061125": { "compartment": "compartment_70101", "id": "reaction_10061125", "reactome": "R-BTA-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629770" ], "products": [ "species_1629765", "species_29370" ], "modifiers": [ [ "species_10060953", "catalyst" ] ], "additional_components": [ "ENSBTAT00000015405" ] }, "reaction_10061113": { "compartment": "compartment_876", "id": "reaction_10061113", "reactome": "R-BTA-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061110", "catalyst" ] ], "additional_components": [ "species_74016", "E1BJE0", "ENSBTAT00000034821", "F1MYF9", "ENSBTAT00000023383", "A0A3Q1MMD9", "ENSBTAT00000074574", "F1MTE8", "ENSBTAT00000078103", "A0A3Q1M8P8", "ENSBTAT00000085120" ] }, "reaction_10061084": { "compartment": "compartment_70101", "id": "reaction_10061084", "reactome": "R-BTA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_994170" ], "products": [ "species_29372", "species_994123" ], "modifiers": [ [ "species_10061081", "catalyst" ] ], "additional_components": [ "E1BBJ7", "ENSBTAT00000025510", "E1BLB5", "ENSBTAT00000022635", "A0A3Q1LJT8", "ENSBTAT00000077857" ] }, "reaction_10061006": { "compartment": "compartment_70101", "id": "reaction_10061006", "reactome": "R-BTA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10061003", "catalyst" ] ], "additional_components": [ "species_74016", "Q1RML2", "ENSBTAT00000017574", "A0A3Q1LVV4", "ENSBTAT00000074229" ] }, "reaction_10060917": { "compartment": "compartment_70101", "id": "reaction_10060917", "reactome": "R-BTA-1855153", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_114520" ], "products": [ "species_29370", "species_994170" ], "modifiers": [ [ "species_10060914", "catalyst" ] ], "additional_components": [ "species_74016", "A0A3Q1LNH2", "ENSBTAT00000070709", "A0A3Q1MR28", "ENSBTAT00000044622", "F1MN32", "ENSBTAT00000025930", "A4FV33", "ENSBTAT00000002194" ] }, "reaction_10061076": { "compartment": "compartment_12045", "id": "reaction_10061076", "reactome": "R-BTA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10061073", "catalyst" ] ], "additional_components": [ "A0A3Q1LJY0", "ENSBTAT00000074483", "species_74016" ] }, "reaction_10036003": { "compartment": "compartment_7660", "id": "reaction_10036003", "reactome": "R-BTA-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10034244", "species_10034248" ], "products": [ "species_10034250" ], "modifiers": [], "additional_components": [ "ENSBTAT00000011684", "ENSBTAT00000061170", "E1BMM0", "ENSBTAT00000061170", "Q3ZBJ1", "ENSBTAT00000011684" ] }, "reaction_10084424": { "compartment": "compartment_13977", "id": "reaction_10084424", "reactome": "R-BTA-8856630", "name": "CIDEA:CIDEC binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084420", "species_8866926" ], "products": [ "species_10084422" ], "modifiers": [], "additional_components": [ "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "A4FUX1", "ENSBTAT00000083406", "A0A3Q1LUM0", "ENSBTAT00000079299" ] }, "reaction_10084480": { "compartment": "compartment_12045", "id": "reaction_10084480", "reactome": "R-BTA-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10084476" ], "products": [ "species_10084478" ], "modifiers": [], "additional_components": [ "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "A4IFN5", "ENSBTAT00000026679", "A0A452DJ11", "ENSBTAT00000028518", "species_549167" ] }, "reaction_10084694": { "compartment": "compartment_70101", "id": "reaction_10084694", "reactome": "R-BTA-8862380", "name": "HSD17B13 binds lipid droplets", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10084690", "species_8866926" ], "products": [ "species_10084692" ], "modifiers": [], "additional_components": [ "ENSBTAT00000038453", "species_549167", "species_8876704", "species_171142", "species_549167", "species_8876704", "species_171142", "Q29RS1", "ENSBTAT00000038453" ] }, "reaction_10083544": { "compartment": "compartment_70101", "id": "reaction_10083544", "reactome": "R-BTA-8848338", "name": "PNPLA4 hydrolyzes TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_549167" ], "products": [ "species_8876730", "species_76103" ], "modifiers": [ [ "species_10083541", "catalyst" ] ], "additional_components": [ "ENSBTAT00000021067" ] }, "reaction_10083547": { "compartment": "compartment_70101", "id": "reaction_10083547", "reactome": "R-BTA-8848355", "name": "PNPLA4 hydrolyzes retinyl palmitate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2534407" ], "products": [ "species_8848337", "species_30209" ], "modifiers": [ [ "species_10083541", "catalyst" ], [ "species_10083337", "inhibitor" ] ], "additional_components": [ "ENSBTAT00000021067", "ENSBTAT00000015669" ] }, "reaction_10071388": { "compartment": "compartment_70101", "id": "reaction_10071388", "reactome": "R-BTA-5334794", "name": "FABPs bind LCFAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8876730", "species_10071384" ], "products": [ "species_10071386" ], "modifiers": [], "additional_components": [ "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "F1MHQ4", "ENSBTAT00000000079", "P80425", "ENSBTAT00000024032", "Q09139", "ENSBTAT00000017593", "F1MFF7", "ENSBTAT00000022662", "F1MRS8", "ENSBTAT00000000867", "A0A452DID8", "ENSBTAT00000014054", "P10790", "ENSBTAT00000022375", "G3N125", "ENSBTAT00000066006", "species_1602366" ] }, "reaction_10035435": { "compartment": "compartment_70101", "id": "reaction_10035435", "reactome": "R-BTA-74213", "name": "Adenine + PRPP => AMP + PPi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10035432", "catalyst" ] ], "additional_components": [ "A0A452DIE3", "ENSBTAT00000000841" ] }, "reaction_10051215": { "compartment": "compartment_70101", "id": "reaction_10051215", "reactome": "R-BTA-514604", "name": "GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113578", "species_29364" ], "products": [ "species_29366", "species_29602", "species_31633" ], "modifiers": [ [ "species_10051212", "catalyst" ] ], "additional_components": [ "F1MCZ0", "ENSBTAT00000003519", "F6R1R5", "ENSBTAT00000020904" ] }, "reaction_10036001": { "compartment": "compartment_70101", "id": "reaction_10036001", "reactome": "R-BTA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76577" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10035998", "catalyst" ] ], "additional_components": [ "E1BA23", "ENSBTAT00000021018", "F1MLX6", "ENSBTAT00000015348", "A0A3Q1M723", "ENSBTAT00000080896" ] }, "reaction_10035426": { "compartment": "compartment_5460", "id": "reaction_10035426", "reactome": "R-BTA-74207", "name": "dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_500224" ], "products": [ "species_113581", "species_500222" ], "modifiers": [ [ "species_10035423", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "CHEBI:28997", "species_109327", "species_109386", "species_2509805", "Q2KIN2", "ENSBTAT00000047239" ] }, "reaction_10036306": { "compartment": "compartment_70101", "id": "reaction_10036306", "reactome": "R-BTA-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_500088", "species_29370" ], "modifiers": [ [ "species_10036303", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "A0A3Q1MB39", "ENSBTAT00000071820", "species_29926" ] }, "reaction_10036308": { "compartment": "compartment_70101", "id": "reaction_10036308", "reactome": "R-BTA-109671", "name": "deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500201", "species_113592" ], "products": [ "species_29370", "species_500199" ], "modifiers": [ [ "species_10034977", "catalyst" ] ], "additional_components": [ "CHEBI:17172", "CHEBI:17256", "species_109386", "species_109327", "Q3MHR2", "ENSBTAT00000016449", "species_29926" ] }, "reaction_10035444": { "compartment": "compartment_70101", "id": "reaction_10035444", "reactome": "R-BTA-74215", "name": "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_500259" ], "products": [ "species_111294", "species_500260" ], "modifiers": [ [ "species_10035441", "catalyst" ] ], "additional_components": [ "species_83956", "species_29850", "species_2509792", "species_113578", "Q3SZ18", "ENSBTAT00000019547", "species_29926" ] }, "reaction_10050378": { "compartment": "compartment_7660", "id": "reaction_10050378", "reactome": "R-BTA-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10050287" ], "products": [ "species_113582", "species_10050298" ], "modifiers": [ [ "species_10050375", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000805", "ENSBTAT00000000805", "ENSBTAT00000078659" ] }, "reaction_10050368": { "compartment": "compartment_7660", "id": "reaction_10050368", "reactome": "R-BTA-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050287", "species_450613" ], "products": [ "species_10050289" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050400": { "compartment": "compartment_7660", "id": "reaction_10050400", "reactome": "R-BTA-450595", "name": "HuR:mRNA complex translocates from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050304" ], "products": [ "species_10050398", "species_10050382" ], "modifiers": [], "additional_components": [ "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000000141" ] }, "reaction_10051219": { "compartment": "compartment_7660", "id": "reaction_10051219", "reactome": "R-BTA-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050293", "species_450605" ], "products": [ "species_10050295" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10050306": { "compartment": "compartment_7660", "id": "reaction_10050306", "reactome": "R-BTA-450387", "name": "HuR binds the CRM1 nuclear export machinery", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050261", "species_10050273", "species_10050302", "species_10050269", "species_10050283", "species_10050265" ], "products": [ "species_10050304" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000141", "ENSBTAT00000029190", "Q3ZCE2", "ENSBTAT00000000805", "ENSBTAT00000016410", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "ENSBTAT00000017629", "E1BE98", "ENSBTAT00000017629", "Q2TBR3", "ENSBTAT00000027913", "A0A3Q1MQB1", "ENSBTAT00000030281", "P51122", "ENSBTAT00000016410", "Q3ZCE2", "ENSBTAT00000000805", "F1MH31", "ENSBTAT00000029190", "Q3ZBM0", "ENSBTAT00000000141" ] }, "reaction_10051221": { "compartment": "compartment_7660", "id": "reaction_10051221", "reactome": "R-BTA-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050298", "species_517622" ], "products": [ "species_10050300" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000805", "Q3ZCE2", "ENSBTAT00000000805" ] }, "reaction_10051066": { "compartment": "compartment_70101", "id": "reaction_10051066", "reactome": "R-BTA-482788", "name": "p-S54,92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050363" ], "products": [ "species_10051064" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050366": { "compartment": "compartment_70101", "id": "reaction_10050366", "reactome": "R-BTA-450474", "name": "MK2 phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050357", "species_113592" ], "products": [ "species_29370", "species_10050363" ], "modifiers": [ [ "species_10040551", "catalyst" ] ], "additional_components": [ "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "ENSBTAT00000084476" ] }, "reaction_10050318": { "compartment": "compartment_70101", "id": "reaction_10050318", "reactome": "R-BTA-450406", "name": "p-S92,203-BRF1 binds 14-3-3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10037666", "species_10050314" ], "products": [ "species_10050316" ], "modifiers": [], "additional_components": [ "ENSBTAT00000022411", "A7MB98", "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778", "A0A140T894", "ENSBTAT00000022411" ] }, "reaction_10050373": { "compartment": "compartment_70101", "id": "reaction_10050373", "reactome": "R-BTA-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450523", "species_10050355" ], "products": [ "species_10050357" ], "modifiers": [], "additional_components": [ "ENSBTAT00000084778", "A7MB98", "ENSBTAT00000084778" ] }, "reaction_10050408": { "compartment": "compartment_70101", "id": "reaction_10050408", "reactome": "R-BTA-450620", "name": "p-S193-KSRP binds 14-3-3zeta in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050402", "species_10050371" ], "products": [ "species_10050406" ], "modifiers": [], "additional_components": [ "ENSBTAT00000000289", "ENSBTAT00000070369", "P63103", "ENSBTAT00000000289", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10050380": { "compartment": "compartment_70101", "id": "reaction_10050380", "reactome": "R-BTA-450592", "name": "KSRP binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10050322", "species_450386" ], "products": [ "species_10050324" ], "modifiers": [], "additional_components": [ "ENSBTAT00000070369", "A0A3Q1N6L6", "ENSBTAT00000070369" ] }, "reaction_10049346": { "compartment": "compartment_876", "id": "reaction_10049346", "reactome": "R-BTA-434381", "name": "CD36 (FAT) translocates palmitate from the extracellular region to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_400452" ], "products": [ "species_3632881" ], "modifiers": [ [ "species_10049343", "catalyst" ] ], "additional_components": [ "ENSBTAT00000080828" ] }, "reaction_10049351": { "compartment": "compartment_17906", "id": "reaction_10049351", "reactome": "R-BTA-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3632881", "species_76194" ], "products": [ "species_1132084", "species_200993", "species_76577" ], "modifiers": [ [ "species_10049348", "catalyst" ] ], "additional_components": [ "ENSBTAT00000022939" ] }, "reaction_10044634": { "compartment": "compartment_70101", "id": "reaction_10044634", "reactome": "R-BTA-265682", "name": "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10044615", "species_113592" ], "products": [ "species_6790050", "species_10044619" ], "modifiers": [ [ "species_10044615", "catalyst" ], [ "species_70113", "catalyst" ], [ "species_10044632", "catalyst" ], [ "species_10044626", "catalyst" ], [ "species_158417", "inhibitor" ] ], "additional_components": [ "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_29926", "species_29370", "A2VDS4", "ENSBTAT00000021523", "species_113592", "E1BKR6", "ENSBTAT00000046676", "A2VDS4", "ENSBTAT00000021523", "species_29370", "species_29926", "E1BKR6", "ENSBTAT00000046676", "species_30389", "A0A3Q1LHN3", "ENSBTAT00000085533", "species_30389", "E1BPX7", "ENSBTAT00000061074" ] }, "reaction_10047765": { "compartment": "compartment_876", "id": "reaction_10047765", "reactome": "R-BTA-400071", "name": "Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_390627", "species_10046203" ], "products": [ "species_10046205" ], "modifiers": [], "additional_components": [ "CHEBI:28918", "species_209789", "ENSBTAT00000065216", "A0A3Q1LQ48", "ENSBTAT00000065216", "CHEBI:28918", "species_209789" ] }, "reaction_10034971": { "compartment": "compartment_70101", "id": "reaction_10034971", "reactome": "R-BTA-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109378" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10034968", "catalyst" ] ], "additional_components": [ "A6QQC3", "ENSBTAT00000083533" ] }, "reaction_10035038": { "compartment": "compartment_70101", "id": "reaction_10035038", "reactome": "R-BTA-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_113592", "species_29494", "species_29472" ], "products": [ "species_29372", "species_29404", "species_29370", "species_110614" ], "modifiers": [ [ "species_10035035", "catalyst" ] ], "additional_components": [ "A0JNE9", "ENSBTAT00000068403" ] }, "reaction_10035698": { "compartment": "compartment_70101", "id": "reaction_10035698", "reactome": "R-BTA-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_500006" ], "products": [ "species_500009", "species_113592" ], "modifiers": [ [ "species_10034909", "catalyst" ] ], "additional_components": [ "species_205687", "CHEBI:28846", "species_110094", "species_727810", "species_109378", "species_109402", "ENSBTAT00000026582" ] }, "reaction_10035029": { "compartment": "compartment_70101", "id": "reaction_10035029", "reactome": "R-BTA-73635", "name": "dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_499997", "species_113592" ], "products": [ "species_29370", "species_499999" ], "modifiers": [ [ "species_10035026", "catalyst" ] ], "additional_components": [ "species_500742", "species_109366", "CHEBI:28850", "CHEBI:18075", "A0A3Q1N7A8", "ENSBTAT00000069715" ] }, "reaction_10036692": { "compartment": "compartment_70101", "id": "reaction_10036692", "reactome": "R-BTA-110144", "name": "ADP + ADP <=> AMP + ATP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370" ], "products": [ "species_113592", "species_76577" ], "modifiers": [ [ "species_10036689", "catalyst" ] ], "additional_components": [ "ENSBTAT00000023406" ] }, "reaction_10034998": { "compartment": "compartment_70101", "id": "reaction_10034998", "reactome": "R-BTA-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111355", "species_109382" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10034995", "catalyst" ] ], "additional_components": [ "species_29926", "A0A3Q1NID0", "ENSBTAT00000077973" ] }, "reaction_10036683": { "compartment": "compartment_70101", "id": "reaction_10036683", "reactome": "R-BTA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_6788778", "species_113592" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "species_76577", "species_727810", "species_109378", "species_109386", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10036938": { "compartment": "compartment_70101", "id": "reaction_10036938", "reactome": "R-BTA-111746", "name": "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10036935", "species_29450" ], "products": [ "species_10036932", "species_111745" ], "modifiers": [ [ "species_10036935", "catalyst" ] ], "additional_components": [ "ENSBTAT00000001575", "ENSBTAT00000001575", "ENSBTAT00000001575" ] }, "reaction_10036685": { "compartment": "compartment_70101", "id": "reaction_10036685", "reactome": "R-BTA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788778", "species_113592" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10036680", "catalyst" ] ], "additional_components": [ "species_76577", "species_727810", "species_109378", "species_109386", "species_29370", "CHEBI:28846", "CHEBI:16174", "species_110094", "A0A3Q1MKM8", "ENSBTAT00000076708", "E1B7Q2", "ENSBTAT00000061550", "F1MUF5", "ENSBTAT00000020294" ] }, "reaction_10051075": { "compartment": "compartment_5460", "id": "reaction_10051075", "reactome": "R-BTA-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_482803" ], "products": [ "species_113581", "species_482807" ], "modifiers": [ [ "species_10051072", "catalyst" ] ], "additional_components": [ "CHEBI:18075", "species_29420", "CHEBI:28850", "CHEBI:28862", "species_205687", "CHEBI:16174", "CHEBI:28846", "species_110094", "species_110614", "species_29438", "species_500739", "species_29892", "species_29494", "species_29604", "species_30185", "species_30187", "F1N6T4", "ENSBTAT00000047964" ] }, "reaction_10077890": { "compartment": "compartment_5460", "id": "reaction_10077890", "reactome": "R-BTA-6788798", "name": "AK4 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_6788802" ], "products": [ "species_113581", "species_6788801" ], "modifiers": [ [ "species_10077887", "catalyst" ] ], "additional_components": [ "species_727810", "species_109386", "species_76577", "species_109378", "species_29370", "CHEBI:16174", "CHEBI:28846", "species_110094", "ENSBTAT00000043366" ] }, "reaction_10082948": { "compartment": "compartment_5460", "id": "reaction_10082948", "reactome": "R-BTA-6810472", "name": "NUDT13 hydrolyses AP6A to AP4 and ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810468", "species_113521" ], "products": [ "species_113581", "species_6810471" ], "modifiers": [ [ "species_10082945", "catalyst" ] ], "additional_components": [ "ENSBTAT00000000407" ] }, "reaction_10035047": { "compartment": "compartment_7660", "id": "reaction_10035047", "reactome": "R-BTA-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742" ], "modifiers": [ [ "species_10035044", "catalyst" ] ], "additional_components": [ "A0A3Q1MT44", "ENSBTAT00000070515" ] }, "reaction_10035481": { "compartment": "compartment_70101", "id": "reaction_10035481", "reactome": "R-BTA-74376", "name": "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29372", "species_500430" ], "products": [ "species_83962", "species_500244" ], "modifiers": [ [ "species_10035476", "catalyst" ] ], "additional_components": [ "CHEBI:16450", "CHEBI:16704", "CHEBI:28542", "species_112016", "F1N0Y0", "ENSBTAT00000011088", "A0A3Q1MGK3", "ENSBTAT00000082335" ] }, "reaction_10034953": { "compartment": "compartment_70101", "id": "reaction_10034953", "reactome": "R-BTA-73589", "name": "5,6-dihydrouracil + H2O => beta-ureidopropionate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73584" ], "products": [ "species_73588" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10036267": { "compartment": "compartment_5460", "id": "reaction_10036267", "reactome": "R-BTA-109514", "name": "TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500420", "species_113521" ], "products": [ "species_113548", "species_500421" ], "modifiers": [ [ "species_10036264", "catalyst" ] ], "additional_components": [ "species_109366", "species_500742", "CHEBI:28895", "species_109402", "CHEBI:28070", "species_83928", "CHEBI:16450", "CHEBI:16704", "species_29926", "E1B8C1", "ENSBTAT00000043576" ] }, "reaction_10036209": { "compartment": "compartment_984", "id": "reaction_10036209", "reactome": "R-BTA-109291", "name": "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_500316" ], "products": [ "species_109277", "species_500318" ], "modifiers": [ [ "species_10036204", "catalyst" ] ], "additional_components": [ "species_109402", "species_727810", "species_109366", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29426", "A0A3Q1MCG3", "ENSBTAT00000074100" ] }, "reaction_10035009": { "compartment": "compartment_70101", "id": "reaction_10035009", "reactome": "R-BTA-73618", "name": "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73541" ], "products": [ "species_73617" ], "modifiers": [ [ "species_10034950", "catalyst" ] ], "additional_components": [ "species_29426", "E1BFN6", "ENSBTAT00000029176" ] }, "reaction_10035011": { "compartment": "compartment_70101", "id": "reaction_10035011", "reactome": "R-BTA-73620", "name": "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73617" ], "products": [ "species_113528", "species_73619", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036258": { "compartment": "compartment_70101", "id": "reaction_10036258", "reactome": "R-BTA-109480", "name": "TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500414" ], "products": [ "species_29372", "species_500415" ], "modifiers": [ [ "species_10036253", "catalyst" ] ], "additional_components": [ "CHEBI:28070", "CHEBI:28895", "species_109366", "species_500742", "CHEBI:46322", "species_109402", "CHEBI:16450", "CHEBI:16704", "species_83928", "G3X6X2", "ENSBTAT00000015317", "species_29926" ] }, "reaction_10034962": { "compartment": "compartment_70101", "id": "reaction_10034962", "reactome": "R-BTA-73591", "name": "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_73588" ], "products": [ "species_113528", "species_73590", "species_31633" ], "modifiers": [ [ "species_10034959", "catalyst" ] ], "additional_components": [ "species_29426", "A0A3Q1MFR9", "ENSBTAT00000086038" ] }, "reaction_10036229": { "compartment": "compartment_70101", "id": "reaction_10036229", "reactome": "R-BTA-109380", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036226", "catalyst" ], [ "species_29370", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "E1BF39", "ENSBTAT00000003884" ] }, "reaction_10036247": { "compartment": "compartment_70101", "id": "reaction_10036247", "reactome": "R-BTA-109449", "name": "(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_500347" ], "products": [ "species_500346", "species_29372" ], "modifiers": [ [ "species_10036244", "catalyst" ] ], "additional_components": [ "species_727810", "species_109378", "species_109366", "species_500742", "species_109402", "CHEBI:15698", "CHEBI:16450", "CHEBI:16704", "species_83928", "CHEBI:17562", "species_29926", "Q32L46", "ENSBTAT00000033700" ] }, "reaction_10065163": { "compartment": "compartment_876", "id": "reaction_10065163", "reactome": "R-BTA-2230938", "name": "Hemoglobin:Haptoglobin:CD163 is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10065129" ], "products": [ "species_10065161" ], "modifiers": [], "additional_components": [ "P85521", "ENSBTAT00000026215", "P01966", "ENSBTAT00000037545", "species_71185", "P02070", "ENSBTAT00000057323", "species_113533", "P85521", "ENSBTAT00000026215", "P02070", "ENSBTAT00000057323", "species_71185", "P01966", "ENSBTAT00000037545", "species_113533" ] }, "reaction_10064765": { "compartment": "compartment_984", "id": "reaction_10064765", "reactome": "R-BTA-2168897", "name": "LRP1 (CD91) binds Hemopexin:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064755", "species_10064761" ], "products": [ "species_10064763" ], "modifiers": [], "additional_components": [ "A0A452DI25", "ENSBTAT00000004635", "species_71185", "ENSBTAT00000017556", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10064753": { "compartment": "compartment_984", "id": "reaction_10064753", "reactome": "R-BTA-2168884", "name": "Ferriheme is transferred from Methemoglobin to Hemopexin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064743", "species_10064747" ], "products": [ "species_10064751", "species_10064749" ], "modifiers": [], "additional_components": [ "P01966", "ENSBTAT00000037545", "species_917955", "P02070", "ENSBTAT00000057323", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_917955", "P01966", "ENSBTAT00000037545", "P02070", "ENSBTAT00000057323" ] }, "reaction_10064757": { "compartment": "compartment_984", "id": "reaction_10064757", "reactome": "R-BTA-2168886", "name": "Hemopexin binds Hemes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310", "species_10064747" ], "products": [ "species_10064755" ], "modifiers": [], "additional_components": [ "species_71185", "ENSBTAT00000004635", "A0A452DI25", "ENSBTAT00000004635", "species_71185" ] }, "reaction_10065173": { "compartment": "compartment_24337", "id": "reaction_10065173", "reactome": "R-BTA-2230983", "name": "LRP1:Hemopexin:heme is endocytosed", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10064763" ], "products": [ "species_10065171" ], "modifiers": [], "additional_components": [ "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "E1BGJ0", "ENSBTAT00000017556", "A0A452DI25", "ENSBTAT00000004635", "species_71185", "species_917955" ] } }, "mod_collapsed_pathways": {}, "degree_dictionary": { "reaction_10087663": 2, "species_10087657": 3, "F1N0R2": 14, "ENSBTAT00000030584": 3, "species_10087661": 2, "reaction_10087795": 2, "species_10087655": 3, "reaction_10087650": 2, "species_10087648": 2, "ENSBTAT00000077926": 3, "species_10049902": 2, "reaction_10087732": 2, "species_10087728": 2, "A0A3Q1LXM0": 10, "species_10087730": 2, "reaction_10088519": 2, "species_10088517": 7, "G3MX29": 7, "ENSBTAT00000064950": 1, "F1MCX4": 31, "ENSBTAT00000015532": 2, "F1N0D6": 87, "ENSBTAT00000004101": 2, "E1BCP6": 91, "ENSBTAT00000015986": 2, "reaction_10045423": 3, "species_374935": 2, "species_209789": 30, "species_10045416": 5, "E1BHW6": 2, "ENSBTAT00000012607": 1, "reaction_10046151": 7, "species_29356": 346, "species_29368": 95, "species_159362": 16, "species_9677997": 1, "species_29382": 11, "species_29408": 11, "species_10037997": 6, "P21398": 2, "ENSBTAT00000021570": 1, "species_113596": 37, "reaction_10046153": 7, "species_8954997": 2, "species_9677992": 1, "reaction_10088657": 5, "species_71284": 19, "species_71285": 16, "species_10088654": 2, "ENSBTAT00000003905": 1, "reaction_10046552": 6, "species_113526": 27, "species_380598": 1, "species_113529": 66, "species_380593": 1, "species_29362": 25, "species_10034212": 3, "P20000": 2, "ENSBTAT00000011521": 1, "reaction_10038000": 7, "species_209914": 20, "species_500604": 1, "reaction_10078658": 3, "species_10078654": 11, "A0A3Q1N4H7": 3, "ENSBTAT00000087280": 1, "A0A3Q1M5L7": 3, "ENSBTAT00000071934": 1, "E1BJH0": 3, "ENSBTAT00000016027": 1, "Q3ZC01": 3, "ENSBTAT00000024009": 1, "A7MB47": 3, "ENSBTAT00000004955": 1, "E1BCS1": 3, "ENSBTAT00000019836": 1, "A6QR51": 3, "ENSBTAT00000023088": 1, "A0A3Q1ME75": 3, "ENSBTAT00000075104": 1, "E1BHL0": 3, "ENSBTAT00000010879": 1, "A0A3Q1N546": 3, "ENSBTAT00000071100": 1, "species_10078604": 2, "ENSBTAT00000020860": 2, "species_10078656": 12, "F1MNK6": 2, "reaction_10081380": 5, "species_113592": 439, "species_10081359": 5, "A0A3Q1LXL7": 7, "ENSBTAT00000054559": 1, "E1BCL3": 7, "ENSBTAT00000053056": 3, "F1MTV9": 7, "A0A3Q1LR94": 7, "species_29370": 392, "species_10081373": 5, "species_10081377": 2, "ENSBTAT00000022307": 1, "reaction_10081499": 2, "species_10037648": 2, "ENSBTAT00000012154": 2, "species_10037650": 2, "Q0VC36": 7, "reaction_10078349": 3, "species_10077951": 3, "ENSBTAT00000033450": 2, "species_10078345": 2, "ENSBTAT00000044590": 3, "species_10078347": 3, "Q2TA06": 5, "Q3ZBN6": 3, "reaction_10077955": 3, "species_10039892": 3, "Q3ZBW4": 19, "ENSBTAT00000007967": 1, "species_10077953": 3, "reaction_10088542": 3, "species_10088530": 3, "ENSBTAT00000022518": 2, "species_10088538": 3, "ENSBTAT00000086675": 2, "species_10088540": 3, "A0A3Q1M173": 3, "A0A452DIR4": 3, "reaction_10088546": 2, "species_10088544": 2, "reaction_10088534": 2, "species_10088532": 2, "reaction_10041386": 8, "species_193055": 6, "species_70106": 193, "species_29364": 106, "species_194037": 1, "species_29366": 107, "species_10041383": 3, "ENSBTAT00000007353": 1, "reaction_10041393": 8, "species_194012": 2, "species_113533": 26, "species_113600": 26, "species_193982": 3, "species_113563": 27, "species_113521": 49, "species_10041390": 4, "ENSBTAT00000055451": 3, "reaction_10041269": 4, "species_196344": 2, "species_10041253": 6, "P14893": 2, "ENSBTAT00000087114": 1, "species_10041267": 5, "P01217": 10, "ENSBTAT00000078886": 2, "P04651": 6, "ENSBTAT00000057054": 3, "reaction_10041397": 8, "species_194005": 2, "reaction_10041719": 6, "species_193103": 3, "species_29360": 41, "species_73473": 36, "reaction_10041415": 8, "species_193988": 3, "reaction_10076281": 6, "species_193132": 4, "species_193066": 4, "species_10076278": 2, "ENSBTAT00000008272": 1, "reaction_10077113": 6, "species_5696835": 1, "species_5696848": 1, "species_10077110": 2, "ENSBTAT00000002073": 2, "reaction_10041277": 9, "species_193079": 3, "species_29460": 10, "species_10041274": 3, "ENSBTAT00000019823": 1, "reaction_10051676": 6, "species_10051673": 2, "Q1JQD0": 2, "ENSBTAT00000064720": 1, "reaction_10041299": 9, "species_193057": 4, "reaction_10084679": 6, "species_176619": 2, "species_10084676": 2, "ENSBTAT00000004193": 1, "reaction_10041692": 3, "species_10041690": 4, "Q28918": 2, "ENSBTAT00000047426": 2, "species_193840": 5, "species_193156": 1, "species_10041688": 3, "reaction_10041716": 4, "species_10041714": 4, "E1BKK4": 3, "ENSBTAT00000015578": 1, "Q0VCL2": 3, "ENSBTAT00000057451": 1, "species_10041712": 3, "reaction_10041684": 6, "species_196095": 1, "species_196066": 1, "species_10041681": 4, "A0A3Q1M9Q1": 2, "ENSBTAT00000078546": 2, "A0A3Q1MBL5": 2, "reaction_10041290": 10, "species_193124": 3, "species_29510": 4, "species_176626": 3, "species_10041281": 5, "ENSBTAT00000074189": 1, "species_10041288": 7, "ENSBTAT00000010386": 4, "reaction_10050650": 7, "species_469662": 3, "species_10050647": 2, "ENSBTAT00000020570": 1, "reaction_10041293": 8, "species_193092": 4, "reaction_10041295": 7, "reaction_10092062": 7, "species_10092059": 2, "ENSBTAT00000004043": 1, "reaction_10041297": 9, "reaction_10092065": 7, "species_10069495": 3, "ENSBTAT00000019855": 1, "reaction_10041284": 8, "reaction_10041721": 6, "species_196366": 2, "reaction_10057880": 3, "species_1449707": 5, "species_194011": 3, "species_10057876": 2, "ENSBTAT00000023402": 2, "species_10057878": 6, "E1BF81": 2, "reaction_10041424": 6, "species_193977": 1, "species_194035": 1, "species_10041421": 2, "F6PTG3": 2, "ENSBTAT00000020078": 1, "reaction_10041379": 3, "reaction_10041395": 8, "species_193966": 1, "reaction_10041412": 9, "species_193998": 1, "species_10041409": 4, "F1MG97": 2, "F1MU47": 2, "ENSBTAT00000006034": 1, "F1MWH3": 2, "reaction_10034240": 6, "species_29398": 9, "species_29708": 3, "species_10033668": 5, "P19858": 2, "ENSBTAT00000056276": 1, "A0A3Q1M4R3": 2, "ENSBTAT00000045699": 1, "E1BNS9": 2, "ENSBTAT00000003234": 1, "reaction_10089721": 3, "species_10089717": 2, "ENSBTAT00000011523": 2, "species_9010792": 2, "species_10089719": 2, "F6Q200": 2, "reaction_10089728": 6, "species_904849": 2, "species_3301973": 2, "species_10089725": 3, "A0A3Q1MEZ2": 4, "ENSBTAT00000075831": 1, "species_29450": 22, "species_1655887": 4, "reaction_10076468": 4, "species_5694074": 1, "species_5694130": 1, "species_10076465": 3, "species_29426": 77, "A4FUZ1": 2, "ENSBTAT00000016884": 1, "reaction_10033671": 6, "reaction_10051980": 5, "species_880013": 1, "species_113594": 17, "species_31649": 14, "species_10051977": 2, "ENSBTAT00000020226": 1, "reaction_10051973": 8, "species_879997": 1, "species_10051970": 2, "ENSBTAT00000081426": 1, "species_880069": 1, "species_880067": 1, "species_113527": 20, "reaction_10033868": 6, "species_113559": 7, "species_113587": 7, "species_29374": 18, "species_29654": 1, "species_10033865": 2, "Q29RK1": 2, "ENSBTAT00000005730": 1, "reaction_10050446": 7, "species_29938": 1, "species_29376": 12, "species_10050443": 3, "Q04467": 4, "ENSBTAT00000018741": 1, "reaction_10089808": 7, "species_113544": 8, "species_113557": 12, "species_10089805": 3, "species_29926": 94, "Q0VCX7": 2, "ENSBTAT00000000306": 1, "reaction_10089795": 9, "species_10089792": 3, "A0A3Q1MWG7": 2, "ENSBTAT00000074198": 1, "species_113588": 1, "species_113593": 22, "reaction_10050437": 7, "species_10050434": 2, "P11024": 2, "ENSBTAT00000080867": 1, "reaction_10089782": 4, "species_10089779": 3, "Q2HJ98": 2, "ENSBTAT00000046873": 1, "reaction_10073835": 2, "species_10039125": 20, "A0A3Q1LSR3": 15, "ENSBTAT00000073291": 1, "species_29438": 321, "F1MG06": 15, "ENSBTAT00000003739": 1, "Q17QU5": 15, "ENSBTAT00000053181": 1, "species_29420": 181, "A0A3Q1MVT8": 24, "ENSBTAT00000075507": 1, "Q0VD29": 24, "ENSBTAT00000012331": 1, "Q3SX43": 24, "ENSBTAT00000031476": 1, "Q3T132": 29, "ENSBTAT00000048084": 1, "Q17QQ1": 29, "ENSBTAT00000047833": 1, "Q2M2U3": 23, "ENSBTAT00000019980": 1, "Q3SZ68": 23, "ENSBTAT00000019928": 1, "A0A3Q1LYC8": 16, "ENSBTAT00000084666": 2, "species_10046585": 15, "reaction_10074507": 3, "species_10074495": 5, "A7MB94": 5, "ENSBTAT00000083637": 1, "Q9GJW7": 7, "ENSBTAT00000019814": 1, "O41515": 9, "ENSBTAT00000015449": 2, "species_1602375": 7, "species_10074505": 5, "species_10052773": 10, "Q3T0U5": 6, "ENSBTAT00000018429": 1, "Q3SX42": 6, "ENSBTAT00000010436": 1, "Q2HJ35": 6, "ENSBTAT00000006291": 1, "A2VDY3": 6, "ENSBTAT00000008352": 1, "Q08E32": 6, "ENSBTAT00000017812": 1, "Q58CS7": 6, "ENSBTAT00000018071": 1, "Q148L0": 6, "ENSBTAT00000018623": 1, "A6H704": 7, "ENSBTAT00000017987": 2, "reaction_10074365": 3, "species_5676030": 1, "species_426639": 10, "species_10074362": 3, "A0A3Q1LMW0": 3, "ENSBTAT00000074360": 1, "A0A3Q1LZ59": 3, "ENSBTAT00000084980": 1, "reaction_10074381": 3, "species_10074371": 2, "ENSBTAT00000023301": 2, "species_10074377": 3, "A0A3Q1LXA9": 10, "ENSBTAT00000077815": 1, "species_10074379": 4, "F1MZE2": 4, "reaction_10074415": 3, "species_10074399": 4, "species_10074413": 5, "reaction_10074142": 5, "species_10073828": 17, "E1BH45": 4, "ENSBTAT00000076195": 1, "Q2HJE0": 4, "ENSBTAT00000000651": 1, "species_10074140": 16, "species_10046570": 10, "species_76577": 61, "F1MQV7": 8, "ENSBTAT00000024965": 1, "F1MBG5": 6, "ENSBTAT00000000017": 1, "Q5BIS9": 6, "ENSBTAT00000007798": 1, "E1B986": 8, "ENSBTAT00000080624": 1, "A0A3Q1MSS5": 8, "ENSBTAT00000086099": 1, "reaction_10074302": 3, "species_5693050": 5, "species_10074298": 3, "A0A3Q1MUP4": 3, "ENSBTAT00000066992": 1, "Q2KJ60": 3, "ENSBTAT00000016002": 1, "species_10074300": 4, "reaction_10090398": 2, "species_10074653": 4, "reaction_10074659": 3, "species_10074655": 2, "ENSBTAT00000083652": 2, "species_10074657": 4, "A4FUE9": 2, "reaction_10070265": 2, "species_10070226": 4, "ENSBTAT00000029455": 4, "species_10070263": 2, "reaction_10070218": 3, "species_10070214": 3, "species_10070210": 5, "D7GLD0": 5, "ENSBTAT00000080672": 1, "A0A3Q1LVE4": 7, "ENSBTAT00000075019": 2, "Q1LZE3": 3, "ENSBTAT00000001994": 1, "F1MPL1": 3, "ENSBTAT00000013860": 1, "species_10070216": 6, "reaction_10070259": 3, "species_10070224": 2, "species_10070256": 8, "A6QPI6": 2, "ENSBTAT00000013405": 1, "Q2KI08": 2, "ENSBTAT00000070920": 1, "Q1LZB5": 2, "ENSBTAT00000032251": 1, "Q08E34": 3, "ENSBTAT00000019001": 2, "A8YXZ8": 2, "ENSBTAT00000046547": 1, "A6H7B1": 4, "ENSBTAT00000000733": 1, "Q56JY4": 2, "ENSBTAT00000011817": 1, "reaction_10070261": 2, "species_10070222": 2, "reaction_10088891": 3, "species_10087624": 2, "ENSBTAT00000002144": 5, "species_10088889": 3, "F1N5S9": 2, "reaction_10087615": 3, "species_10087608": 3, "species_10087605": 2, "species_10087612": 2, "ENSBTAT00000009887": 1, "reaction_10087621": 5, "species_10087618": 2, "species_10040957": 5, "ENSBTAT00000011767": 7, "reaction_10073831": 4, "species_10073822": 16, "reaction_10050514": 3, "species_210382": 17, "species_10050510": 11, "A2VE57": 3, "ENSBTAT00000070796": 1, "species_352022": 26, "Q2HJD2": 3, "ENSBTAT00000015567": 1, "A0A3Q1M9Y0": 5, "ENSBTAT00000073656": 1, "F1MM66": 8, "ENSBTAT00000003326": 2, "A0A3Q1MR28": 17, "ENSBTAT00000044622": 3, "A0A3Q1MBH0": 7, "ENSBTAT00000084144": 1, "P61602": 3, "ENSBTAT00000068404": 1, "A0A3Q1MFJ1": 5, "ENSBTAT00000077778": 1, "F1MCW8": 3, "ENSBTAT00000022788": 1, "species_10050512": 13, "reaction_10050517": 3, "species_74112": 16, "species_74016": 106, "reaction_10045419": 3, "reaction_10045421": 7, "species_5279533": 1, "reaction_10039481": 4, "species_10039473": 7, "ENSBTAT00000021630": 2, "species_10039469": 2, "ENSBTAT00000018325": 2, "species_10039475": 3, "E1B847": 2, "Q3ZCC3": 16, "species_10039479": 2, "ENSBTAT00000020029": 2, "reaction_10050256": 2, "species_10039518": 3, "A0A3Q1LWJ8": 4, "ENSBTAT00000087439": 4, "A0A3Q1LJU7": 3, "ENSBTAT00000082454": 1, "species_10039505": 4, "reaction_10042826": 5, "species_113518": 32, "species_10041947": 4, "A5PKJ4": 5, "ENSBTAT00000001347": 3, "species_113550": 11, "species_10042805": 3, "species_10042823": 2, "F1N1S8": 2, "ENSBTAT00000007277": 1, "reaction_10043488": 6, "species_10043479": 5, "Q2T9T7": 3, "ENSBTAT00000078874": 1, "F1MM08": 2, "ENSBTAT00000061049": 1, "A6QLS1": 2, "ENSBTAT00000029212": 1, "Q2KJ36": 2, "ENSBTAT00000006022": 1, "species_10043486": 3, "Q2YDN8": 2, "ENSBTAT00000007054": 1, "reaction_10041950": 5, "species_29358": 67, "species_10041927": 3, "A0A3Q1MLN6": 5, "ENSBTAT00000073341": 1, "A0A3Q1LNQ6": 5, "ENSBTAT00000080174": 1, "species_113582": 66, "species_10041945": 3, "reaction_10050208": 3, "species_10039493": 3, "ENSBTAT00000005279": 3, "species_10050204": 2, "ENSBTAT00000005660": 2, "species_10050206": 3, "O77628": 2, "Q08DH1": 2, "reaction_10039508": 5, "species_10039489": 2, "reaction_10050218": 2, "species_10050214": 4, "ENSBTAT00000081307": 3, "species_10050216": 4, "reaction_10050254": 5, "species_10050233": 3, "species_10050251": 8, "E1B7Z0": 3, "ENSBTAT00000077920": 1, "A0A3Q1M7T8": 3, "ENSBTAT00000082809": 1, "A0A3Q1LT51": 3, "ENSBTAT00000068866": 1, "P0CG53": 74, "ENSBTAT00000022919": 5, "A0A3Q1LU30": 84, "ENSBTAT00000087088": 3, "P63048": 83, "ENSBTAT00000010176": 4, "reaction_10050192": 4, "species_10050185": 5, "A0A3Q1M614": 5, "ENSBTAT00000084476": 3, "G3X793": 12, "ENSBTAT00000022358": 1, "A0A3Q1LTT9": 16, "ENSBTAT00000073013": 3, "species_10050189": 5, "reaction_10050196": 2, "species_10050194": 4, "reaction_10050231": 5, "species_10050228": 4, "reaction_10069253": 5, "species_10037313": 10, "P61585": 32, "ENSBTAT00000005600": 2, "species_10037315": 13, "species_10069250": 18, "A7MB57": 22, "ENSBTAT00000070883": 1, "E1BIM8": 52, "A0JNB0": 60, "ENSBTAT00000015730": 2, "F1N261": 38, "ENSBTAT00000075171": 4, "A6QLY0": 11, "ENSBTAT00000033972": 1, "Q3ZC64": 11, "ENSBTAT00000004007": 1, "Q17R05": 11, "ENSBTAT00000080646": 1, "A5D7J8": 11, "ENSBTAT00000053096": 1, "F1N163": 11, "ENSBTAT00000026958": 1, "F1N6H6": 11, "ENSBTAT00000033263": 1, "A0A3Q1MTB6": 11, "ENSBTAT00000067384": 1, "E1BJS9": 11, "ENSBTAT00000008955": 1, "F1MKR1": 11, "ENSBTAT00000037789": 1, "E1BER5": 11, "ENSBTAT00000013238": 1, "A0A3Q1MAA9": 11, "ENSBTAT00000083978": 1, "A0A3Q1MJW2": 11, "ENSBTAT00000075696": 1, "Q08DA6": 4, "ENSBTAT00000011773": 1, "reaction_10077455": 3, "species_10077414": 2, "ENSBTAT00000076709": 2, "species_10049952": 3, "species_10077416": 5, "E1BAT3": 4, "reaction_10077422": 3, "species_10049956": 2, "ENSBTAT00000023595": 3, "species_10077418": 6, "F1N366": 3, "ENSBTAT00000021515": 2, "species_10077420": 6, "E1BD36": 29, "reaction_10077424": 3, "species_10077410": 2, "reaction_10065517": 5, "species_179856": 35, "species_179838": 74, "species_10065514": 20, "A0A3Q1MHG9": 14, "ENSBTAT00000075168": 3, "F1MI53": 2, "ENSBTAT00000074586": 1, "A0A3Q1NAW3": 4, "ENSBTAT00000070846": 1, "A0A2Z2AM52": 2, "ENSBTAT00000080723": 1, "A3R3B5": 2, "ENSBTAT00000077363": 2, "A0A3Q1M7L0": 2, "ENSBTAT00000075285": 1, "A8E4Q0": 2, "ENSBTAT00000031648": 1, "A0A3Q1NM98": 2, "ENSBTAT00000071353": 1, "F1MHY4": 2, "ENSBTAT00000006472": 1, "A3R3B4": 2, "F1MPK9": 2, "ENSBTAT00000055860": 1, "A0A140T8B5": 2, "ENSBTAT00000037859": 1, "A0A3Q1N4Y9": 2, "ENSBTAT00000068807": 1, "A0A3Q1MU93": 23, "ENSBTAT00000086688": 1, "P01888": 23, "ENSBTAT00000016359": 1, "P32871": 26, "ENSBTAT00000072391": 2, "F1MYM3": 14, "ENSBTAT00000009083": 1, "P23726": 14, "ENSBTAT00000003033": 1, "reaction_10065491": 5, "species_10040312": 30, "A0A3Q1LKB7": 33, "ENSBTAT00000071009": 1, "A5D7R9": 31, "ENSBTAT00000012897": 1, "species_10039728": 32, "species_10065488": 4, "Q0IIE2": 58, "ENSBTAT00000075224": 8, "F1N7C3": 42, "ENSBTAT00000015471": 2, "Q3T0F9": 88, "ENSBTAT00000006216": 2, "reaction_10040851": 2, "species_10040846": 2, "ENSBTAT00000027331": 2, "species_10040848": 2, "O18968": 2, "reaction_10049067": 3, "species_114565": 1, "species_10049064": 2, "ENSBTAT00000013298": 2, "reaction_10051002": 2, "species_10050998": 2, "ENSBTAT00000009564": 3, "species_10051000": 4, "reaction_10050924": 2, "species_10050904": 18, "A7E3W2": 3, "ENSBTAT00000001802": 1, "Q29RS5": 3, "ENSBTAT00000084323": 1, "A0A3Q1M5Q6": 3, "ENSBTAT00000076112": 1, "A5PKI3": 3, "ENSBTAT00000073296": 1, "species_29372": 164, "A0A452DIU4": 3, "ENSBTAT00000024391": 1, "A0A3Q1LTE4": 3, "ENSBTAT00000080253": 1, "Q27967": 5, "ENSBTAT00000002631": 1, "species_111294": 56, "A6H754": 3, "ENSBTAT00000022777": 1, "species_10050922": 18, "reaction_10050994": 2, "species_10050980": 10, "F1MTN1": 7, "ENSBTAT00000013173": 1, "F1MGZ4": 7, "ENSBTAT00000010738": 1, "A0A3Q1LI93": 3, "ENSBTAT00000075662": 1, "P26201": 5, "ENSBTAT00000080828": 2, "A0A3Q1MHJ9": 12, "ENSBTAT00000086833": 3, "A5PK28": 3, "ENSBTAT00000067657": 1, "A0A3Q1LEU1": 5, "ENSBTAT00000081148": 1, "A0A3Q1LN74": 3, "ENSBTAT00000074339": 1, "A0A1L6ZA12": 3, "ENSBTAT00000087233": 1, "species_10050992": 10, "reaction_10050948": 2, "species_10050938": 4, "Q8HZJ5": 3, "ENSBTAT00000078091": 1, "A0A3Q1N8P4": 7, "ENSBTAT00000066443": 1, "Q9XSK2": 5, "ENSBTAT00000015829": 1, "species_10050946": 4, "reaction_10050870": 2, "species_10050802": 38, "A0A452DIX0": 3, "ENSBTAT00000026577": 1, "P17697": 5, "ENSBTAT00000007324": 1, "A4IF69": 3, "ENSBTAT00000004806": 1, "F1MY12": 5, "ENSBTAT00000016092": 1, "A0A140T8C8": 14, "ENSBTAT00000053071": 3, "A0A0A0MP92": 7, "ENSBTAT00000011576": 1, "C4PU73": 7, "ENSBTAT00000009718": 1, "A0A0A0MPA0": 7, "ENSBTAT00000038516": 1, "G3N1U4": 7, "ENSBTAT00000064475": 1, "A0A3Q1MGZ6": 7, "ENSBTAT00000077453": 1, "A0A0A0MP89": 7, "ENSBTAT00000009261": 1, "A0A452DJK6": 7, "ENSBTAT00000064935": 1, "E1BMJ0": 6, "ENSBTAT00000021638": 3, "Q9XS50": 6, "ENSBTAT00000019613": 2, "A0A3Q1N9Y5": 9, "ENSBTAT00000085713": 1, "P28800": 4, "ENSBTAT00000027793": 2, "P34955": 7, "ENSBTAT00000072441": 1, "Q3T0A3": 7, "ENSBTAT00000063284": 1, "A6QP91": 5, "ENSBTAT00000015925": 1, "E1BBY0": 3, "ENSBTAT00000051964": 1, "E1B726": 13, "ENSBTAT00000001674": 2, "A0A452DIJ9": 6, "ENSBTAT00000019232": 2, "G3X7J5": 3, "ENSBTAT00000032623": 1, "F1MD83": 3, "ENSBTAT00000015874": 1, "Q5GN72": 9, "ENSBTAT00000022991": 1, "A0A3Q1M2H1": 3, "ENSBTAT00000067311": 1, "Q17QL4": 3, "ENSBTAT00000007016": 1, "A4IFA6": 3, "ENSBTAT00000007913": 1, "F1N0I3": 8, "ENSBTAT00000023573": 3, "A0A3Q1LPG8": 3, "ENSBTAT00000083114": 1, "G5E5W1": 7, "ENSBTAT00000036726": 5, "P12763": 7, "ENSBTAT00000000673": 1, "F1MX05": 3, "ENSBTAT00000004949": 1, "G8JKY5": 3, "ENSBTAT00000024387": 1, "A0A3Q1LMG1": 10, "ENSBTAT00000083687": 1, "Q2HJ33": 3, "ENSBTAT00000009160": 1, "P07455": 4, "ENSBTAT00000014713": 2, "species_10050868": 38, "reaction_10051062": 2, "species_10051036": 12, "F1MHC2": 3, "ENSBTAT00000012094": 1, "P80513": 3, "ENSBTAT00000045083": 1, "P63258": 12, "ENSBTAT00000008132": 1, "F1MRZ8": 3, "ENSBTAT00000012724": 1, "A0A3Q1MLQ7": 5, "ENSBTAT00000074863": 1, "A7YY77": 3, "ENSBTAT00000034535": 1, "F1MNQ4": 8, "ENSBTAT00000039344": 1, "A0A3Q1LP13": 3, "ENSBTAT00000075491": 1, "E1B8Z0": 3, "ENSBTAT00000079099": 1, "Q5E9F5": 3, "ENSBTAT00000080925": 1, "species_10051060": 12, "reaction_10090306": 3, "species_10090272": 4, "A5D7J5": 4, "ENSBTAT00000024876": 1, "species_10090302": 5, "F1MWY5": 4, "ENSBTAT00000023764": 1, "A6H720": 11, "ENSBTAT00000069542": 2, "Q08E52": 15, "ENSBTAT00000080749": 3, "Q17QZ0": 5, "ENSBTAT00000086158": 1, "species_10090304": 7, "reaction_10090311": 4, "species_10090308": 3, "reaction_10081497": 5, "species_6803743": 2, "species_193473": 1, "species_449701": 3, "species_10081494": 2, "ENSBTAT00000074115": 1, "reaction_10050153": 5, "species_29512": 7, "species_29472": 19, "species_29404": 28, "species_10050150": 3, "F1MZY2": 2, "ENSBTAT00000023441": 1, "A0A452DHW0": 2, "ENSBTAT00000002867": 1, "reaction_10081490": 6, "species_6803785": 3, "CHEBI:27459": 1, "species_1678743": 7, "species_6803738": 3, "species_449703": 2, "species_10081487": 2, "A0A452DJF8": 2, "ENSBTAT00000019528": 1, "reaction_10049778": 3, "species_532204": 1, "species_10049775": 2, "ENSBTAT00000086526": 1, "reaction_10069593": 4, "species_10033408": 40, "species_10069585": 2, "ENSBTAT00000072372": 2, "species_10069588": 2, "species_10069590": 5, "F6RHP0": 3, "ENSBTAT00000032504": 1, "A0A3Q1MSZ4": 19, "ENSBTAT00000078307": 2, "F1MLS5": 3, "ENSBTAT00000043725": 3, "reaction_10069595": 3, "species_10069581": 3, "species_10042973": 4, "reaction_10069872": 3, "species_10069868": 2, "F1MGM1": 5, "ENSBTAT00000027911": 1, "species_10067196": 4, "ENSBTAT00000026930": 2, "species_10069870": 3, "E1BDG5": 16, "reaction_10044480": 8, "species_113534": 41, "species_156540": 39, "species_215557": 1, "species_113601": 39, "species_113519": 55, "species_113564": 37, "species_571314": 1, "species_10044148": 8, "M0QW30": 4, "ENSBTAT00000072981": 2, "A0A3Q1MCJ2": 5, "ENSBTAT00000073532": 1, "A0A3Q1MU89": 4, "F1MCD3": 4, "ENSBTAT00000036364": 1, "reaction_10071909": 8, "species_2142713": 1, "species_5602281": 1, "species_10035953": 2, "ENSBTAT00000066325": 1, "reaction_10044151": 8, "species_266056": 1, "species_2161636": 2, "reaction_10073037": 3, "species_10035491": 24, "species_10073033": 16, "F1N4S9": 26, "ENSBTAT00000019297": 2, "F1MN51": 28, "ENSBTAT00000013942": 2, "E1BFP8": 29, "ENSBTAT00000022973": 2, "species_190915": 102, "D8KXU9": 90, "ENSBTAT00000064356": 1, "P03968": 96, "ENSBTAT00000078959": 1, "G3XGD3": 89, "ENSBTAT00000029946": 1, "G3MXR4": 90, "ENSBTAT00000065993": 1, "E1BHC1": 69, "ENSBTAT00000016675": 1, "E1BP37": 90, "ENSBTAT00000061318": 1, "E1BJU2": 92, "ENSBTAT00000008940": 4, "F1N6G8": 92, "ENSBTAT00000002001": 1, "F1MHC6": 63, "ENSBTAT00000008839": 1, "species_10073035": 18, "reaction_10073041": 3, "species_10072995": 5, "species_10065241": 17, "species_10073039": 16, "reaction_10073044": 5, "reaction_10073047": 4, "reaction_10076847": 8, "species_29870": 4, "species_5696122": 1, "species_1497857": 1, "species_76116": 10, "species_5696116": 2, "species_10076844": 2, "ENSBTAT00000069764": 1, "reaction_10035838": 5, "species_75967": 1, "species_76103": 4, "species_549167": 7, "species_76194": 61, "species_10035835": 3, "F1MIW3": 4, "ENSBTAT00000037423": 1, "reaction_10035795": 5, "species_76114": 4, "species_10035790": 2, "ENSBTAT00000030932": 1, "reaction_10035829": 5, "species_76108": 2, "species_10035826": 3, "A0A3Q1LKP8": 5, "ENSBTAT00000083005": 1, "A0A3Q1LV95": 3, "ENSBTAT00000067199": 1, "reaction_10080887": 5, "species_6800352": 1, "species_1500578": 20, "species_10080884": 4, "Q70VZ7": 2, "ENSBTAT00000011091": 1, "F1MLQ3": 2, "ENSBTAT00000010395": 1, "G3MYF6": 2, "ENSBTAT00000064201": 1, "reaction_10090409": 5, "species_10090404": 3, "ENSBTAT00000011536": 1, "species_10090406": 2, "ENSBTAT00000061563": 1, "reaction_10044826": 5, "species_10044815": 3, "P84080": 7, "ENSBTAT00000010159": 1, "species_10044819": 3, "species_10044823": 3, "ENSBTAT00000061619": 3, "reaction_10045538": 7, "species_10045527": 4, "ENSBTAT00000009899": 3, "species_10045525": 3, "ENSBTAT00000085048": 2, "species_10045531": 2, "ENSBTAT00000033040": 3, "species_10045533": 3, "species_10045535": 4, "Q3T0Y8": 9, "A0A3Q1MED5": 6, "A0A452DIB2": 5, "reaction_10034921": 5, "species_111628": 2, "species_76630": 1, "species_10034918": 4, "F1MVC0": 2, "ENSBTAT00000023783": 1, "reaction_10034924": 5, "species_111647": 2, "species_29448": 12, "reaction_10034927": 9, "species_111627": 9, "reaction_10048761": 5, "species_109277": 14, "species_74113": 48, "species_83910": 55, "species_10048758": 2, "ENSBTAT00000084837": 1, "reaction_10048754": 5, "species_10048751": 2, "ENSBTAT00000069253": 1, "reaction_10065819": 4, "species_10065294": 3, "ENSBTAT00000004562": 4, "species_10065814": 2, "species_10065812": 2, "species_10065816": 3, "F1MU56": 6, "ENSBTAT00000006029": 7, "F1MTX6": 9, "ENSBTAT00000013124": 8, "reaction_10059674": 3, "species_10059657": 2, "A0A3Q1MEV3": 6, "ENSBTAT00000068399": 2, "species_10059665": 2, "species_10059671": 5, "A0A3Q1M4A6": 4, "ENSBTAT00000081947": 2, "G3MWP1": 10, "ENSBTAT00000064480": 2, "reaction_10087324": 6, "species_10087311": 2, "ENSBTAT00000018286": 5, "species_10087319": 2, "species_10087317": 2, "species_10087315": 2, "species_10087321": 2, "species_10058184": 4, "reaction_10064649": 3, "species_10064303": 2, "F6RND5": 6, "ENSBTAT00000039811": 3, "species_10064625": 2, "species_10064623": 2, "reaction_10076984": 6, "species_5696409": 2, "species_113548": 13, "species_5693978": 3, "species_113556": 1, "species_10076981": 2, "E1B8R9": 2, "ENSBTAT00000018115": 1, "reaction_10059533": 3, "species_10059526": 6, "A0A3Q1LLV2": 6, "ENSBTAT00000083510": 1, "A0A3Q1NK51": 10, "ENSBTAT00000083333": 1, "A0A3Q1M970": 10, "ENSBTAT00000070553": 1, "species_10058166": 3, "species_10059530": 4, "reaction_10059598": 3, "species_10058699": 4, "G3MZI7": 13, "ENSBTAT00000063052": 2, "A0A3Q1MDT9": 13, "ENSBTAT00000084344": 2, "F1MJQ6": 13, "ENSBTAT00000013440": 2, "species_10059595": 4, "species_10059528": 3, "reaction_10058561": 3, "species_10058552": 2, "P02459": 16, "ENSBTAT00000017505": 2, "species_10057938": 2, "species_10058558": 5, "F1MT97": 3, "ENSBTAT00000021014": 7, "G3N0J0": 7, "ENSBTAT00000063400": 3, "A7YWU9": 12, "ENSBTAT00000028731": 5, "reaction_10059441": 3, "species_10059282": 5, "E1BI98": 13, "ENSBTAT00000015668": 2, "F1MKG2": 13, "ENSBTAT00000025663": 2, "E1BB91": 13, "ENSBTAT00000018479": 2, "species_10059434": 4, "species_10059438": 2, "ENSBTAT00000008025": 2, "reaction_10064705": 3, "species_10064651": 2, "A0A3Q1M0N0": 6, "ENSBTAT00000072268": 3, "species_10064677": 2, "species_10064703": 2, "reaction_10058193": 2, "species_10058168": 6, "A7E303": 9, "ENSBTAT00000018159": 2, "F1MJR6": 9, "ENSBTAT00000083731": 2, "species_10058190": 6, "reaction_10059651": 3, "species_10059648": 3, "species_10058052": 3, "species_10058172": 3, "reaction_10059689": 3, "species_10059684": 3, "species_10059686": 4, "F1MMD4": 2, "reaction_10059913": 4, "species_10059733": 3, "species_10059908": 2, "species_10059906": 3, "species_10059910": 2, "reaction_10059787": 4, "species_10059746": 2, "species_10059750": 2, "species_10059748": 3, "species_10059784": 7, "Q2KJ63": 7, "ENSBTAT00000012503": 2, "A5PJB8": 4, "ENSBTAT00000053990": 2, "A7YWU6": 4, "A0A3Q1LWD8": 4, "ENSBTAT00000076474": 1, "reaction_10059869": 3, "species_10059862": 2, "species_10059866": 6, "reaction_10059804": 3, "species_10059793": 2, "species_10058188": 2, "species_10059801": 5, "Q6H320": 2, "ENSBTAT00000024677": 1, "reaction_10059902": 3, "species_10059706": 3, "species_10059899": 2, "reaction_10059918": 3, "species_10058180": 2, "species_10059915": 2, "reaction_10059744": 4, "species_10059735": 2, "species_10059741": 3, "P25975": 2, "ENSBTAT00000036427": 3, "reaction_10059731": 4, "species_10059704": 2, "species_10059708": 2, "species_10059728": 9, "A6QPI9": 2, "ENSBTAT00000009636": 1, "E1BAD2": 6, "ENSBTAT00000054741": 2, "E1B8U1": 2, "ENSBTAT00000052512": 1, "E1BIP7": 2, "ENSBTAT00000011737": 1, "reaction_10059923": 4, "species_10059920": 2, "species_1604783": 3, "CHEBI:24505": 3, "species_444761": 3, "reaction_10060003": 2, "species_10059897": 2, "F1N797": 3, "ENSBTAT00000061368": 1, "species_10060001": 2, "reaction_10068885": 4, "species_10059693": 4, "ENSBTAT00000022744": 6, "species_10068874": 2, "species_10068872": 3, "species_10068882": 5, "F1MF35": 2, "ENSBTAT00000015593": 1, "E1BEV7": 4, "ENSBTAT00000001218": 1, "A0A452DK38": 4, "F1N0X6": 3, "ENSBTAT00000007834": 1, "reaction_10065751": 3, "species_10063837": 4, "F1MTZ4": 7, "ENSBTAT00000020360": 1, "species_10065748": 2, "species_10058176": 2, "reaction_10087543": 2, "species_10087535": 2, "ENSBTAT00000068477": 2, "species_10087541": 2, "A0A3Q1MG91": 2, "reaction_10059702": 4, "species_10059697": 2, "species_10059695": 2, "species_10059699": 3, "reaction_10061174": 3, "species_10061170": 2, "ENSBTAT00000029116": 2, "species_10039426": 15, "G3N0V0": 8, "ENSBTAT00000066155": 1, "A0A3Q1M0K3": 11, "ENSBTAT00000085031": 11, "A0A3Q1M458": 11, "A0A3Q1M667": 11, "A0A3Q1MFI7": 11, "ENSBTAT00000081783": 1, "A0A3Q1LKV0": 11, "A0A3Q1LLT0": 11, "G3N188": 11, "G3N1H5": 11, "ENSBTAT00000064325": 1, "G3N3Q3": 11, "A0A3Q1MI29": 11, "A0A3Q1ML26": 11, "G3MXG6": 11, "G3N148": 11, "species_10061172": 16, "F1MHH9": 4, "reaction_10033690": 6, "species_113552": 11, "species_30471": 2, "species_10033687": 2, "ENSBTAT00000021616": 1, "species_374064": 1, "reaction_10033706": 5, "species_29468": 3, "species_29514": 6, "species_29498": 3, "species_10033703": 3, "Q2KJ64": 6, "ENSBTAT00000016461": 1, "reaction_10033770": 5, "species_113567": 1, "species_113585": 1, "species_29968": 3, "species_10033767": 3, "Q2KHW4": 2, "ENSBTAT00000015468": 1, "A0A3Q1N1S4": 2, "ENSBTAT00000015847": 1, "reaction_10033697": 8, "species_113561": 2, "species_29896": 3, "species_113581": 17, "species_29676": 1, "species_10033694": 2, "ENSBTAT00000022158": 1, "reaction_10084008": 4, "species_10083994": 3, "Q2TA10": 12, "ENSBTAT00000055368": 2, "A0A3Q1M5N0": 11, "ENSBTAT00000066609": 1, "species_10083992": 5, "F1ME38": 3, "ENSBTAT00000008985": 1, "species_10084006": 6, "species_10083996": 5, "reaction_10084122": 5, "species_10084119": 2, "species_10033406": 2, "species_10033404": 2, "species_10033402": 2, "species_10075812": 2, "ENSBTAT00000026356": 2, "reaction_10084113": 4, "species_10033394": 3, "species_10034499": 2, "species_10084110": 4, "F1N556": 4, "ENSBTAT00000007177": 2, "G5E630": 2, "ENSBTAT00000050390": 1, "reaction_10084117": 4, "species_10084115": 2, "species_10033398": 2, "species_10034743": 2, "reaction_10086702": 4, "species_10086688": 3, "ENSBTAT00000024336": 2, "species_10086698": 9, "Q1RMX2": 9, "ENSBTAT00000055723": 1, "A0A3Q1MAR8": 7, "ENSBTAT00000084854": 2, "species_10043291": 5, "ENSBTAT00000018398": 4, "species_10086700": 11, "Q17QJ6": 15, "Q3T0W3": 2, "reaction_10086710": 5, "species_10086707": 5, "species_10086705": 2, "reaction_10047210": 3, "species_10045758": 4, "F1MCK3": 5, "ENSBTAT00000055896": 1, "A0A452DI80": 5, "ENSBTAT00000010601": 1, "F1N5C5": 5, "ENSBTAT00000015383": 1, "species_372533": 13, "species_10045760": 5, "reaction_10047214": 3, "species_10046209": 2, "ENSBTAT00000019534": 2, "species_10046211": 3, "P41985": 6, "reaction_10047224": 3, "species_380873": 3, "species_10046197": 2, "ENSBTAT00000002768": 2, "species_10046199": 3, "F1N454": 4, "reaction_10091556": 3, "species_10091552": 2, "ENSBTAT00000014422": 2, "species_10091554": 3, "F1N4I3": 2, "reaction_10047222": 3, "species_10047218": 2, "ENSBTAT00000062955": 2, "species_10047220": 3, "Q95136": 2, "reaction_10091929": 3, "species_10091925": 2, "ENSBTAT00000054712": 2, "species_114523": 5, "species_10091927": 3, "F6Q2H9": 2, "reaction_10047256": 3, "species_10047252": 4, "A0A3Q1MLD1": 3, "ENSBTAT00000067375": 1, "E1BE22": 3, "ENSBTAT00000010513": 1, "E1BD86": 5, "ENSBTAT00000011575": 1, "species_10047254": 5, "reaction_10047236": 3, "species_10046185": 6, "F1MMU1": 5, "ENSBTAT00000054307": 1, "F1MB93": 5, "ENSBTAT00000037840": 1, "F6R5F6": 5, "ENSBTAT00000052346": 1, "F1MGM3": 5, "ENSBTAT00000061041": 1, "E1BGY8": 5, "ENSBTAT00000003759": 1, "species_10046187": 7, "reaction_10047238": 3, "species_10045782": 3, "A0A452DIJ2": 5, "ENSBTAT00000017943": 1, "F6QI78": 5, "ENSBTAT00000052796": 1, "species_10045784": 4, "reaction_10047226": 3, "species_10046191": 2, "ENSBTAT00000048201": 2, "species_390899": 15, "species_10046193": 3, "E1BBS2": 4, "reaction_10091825": 3, "species_10091821": 2, "ENSBTAT00000020802": 2, "species_10091823": 3, "F1MML8": 2, "reaction_10047234": 3, "species_10047230": 2, "ENSBTAT00000061359": 2, "species_10047232": 3, "E1BK27": 2, "reaction_10090968": 5, "species_390627": 7, "CHEBI:28918": 27, "species_10051599": 3, "ENSBTAT00000085511": 2, "species_10051601": 4, "A0A3Q1MQZ8": 5, "species_10090958": 3, "species_10090923": 5, "Q28044": 11, "ENSBTAT00000002779": 2, "reaction_10090925": 3, "species_9609307": 1, "species_10090921": 3, "reaction_10047212": 3, "species_10046203": 3, "ENSBTAT00000065216": 2, "species_10046205": 6, "A0A3Q1LQ48": 6, "reaction_10090960": 3, "species_9611836": 1, "reaction_10090964": 5, "species_10051593": 2, "species_10051595": 5, "species_10090962": 2, "reaction_10047206": 5, "species_10045770": 3, "E1B7W0": 9, "ENSBTAT00000025981": 1, "F1MGA6": 9, "ENSBTAT00000055443": 1, "species_10045772": 5, "species_10047204": 3, "species_10047202": 3, "reaction_10047332": 3, "species_10047328": 2, "F1N0G5": 3, "ENSBTAT00000054907": 1, "species_391200": 2, "species_10047330": 3, "reaction_10083878": 3, "species_8851314": 4, "species_10046122": 2, "ENSBTAT00000008485": 2, "species_10046124": 3, "G5E581": 4, "reaction_10038450": 4, "species_30389": 17, "species_10038447": 2, "ENSBTAT00000006874": 2, "reaction_10036570": 5, "species_10036567": 33, "F1MYE0": 10, "ENSBTAT00000028392": 1, "F1MJE0": 16, "ENSBTAT00000015938": 1, "A2VE24": 28, "ENSBTAT00000006962": 1, "F1MRU0": 28, "ENSBTAT00000024717": 2, "A0A3Q1M864": 15, "ENSBTAT00000084533": 2, "E1B7I9": 53, "ENSBTAT00000025495": 3, "A0A3Q1MPT9": 22, "ENSBTAT00000086336": 3, "E1BGY3": 47, "ENSBTAT00000011373": 1, "A0A3Q1NAV6": 49, "ENSBTAT00000086367": 1, "A0A3Q1NNL0": 49, "ENSBTAT00000086016": 1, "A0A3Q1LUE0": 30, "ENSBTAT00000083788": 3, "A0A3Q1LRU7": 22, "ENSBTAT00000072473": 3, "E1BAI2": 27, "ENSBTAT00000018586": 1, "A0A3Q1M3Q3": 23, "ENSBTAT00000073054": 1, "F1N339": 44, "ENSBTAT00000002653": 2, "reaction_10036607": 5, "species_10036588": 4, "A0A3Q1NH21": 4, "ENSBTAT00000076493": 1, "species_10036604": 3, "species_10036596": 5, "F1MQJ7": 16, "ENSBTAT00000039221": 3, "reaction_10036590": 4, "species_10036586": 4, "E1BA10": 4, "ENSBTAP00000020594": 1, "Q0VCE3": 3, "ENSBTAT00000022616": 1, "species_10036580": 3, "reaction_10036598": 3, "species_10036594": 4, "reaction_10035507": 3, "species_10035503": 5, "species_10035505": 5, "reaction_10035527": 3, "species_10035523": 9, "species_10035525": 6, "reaction_10055817": 2, "species_10055815": 19, "Q3ZCC9": 9, "ENSBTAT00000023702": 1, "A0A3Q1MUW6": 20, "ENSBTAT00000080813": 2, "E1BI37": 22, "ENSBTAT00000035878": 2, "F1MZQ5": 20, "F1N4Y5": 20, "ENSBTAT00000021451": 1, "A0A3Q1LRW6": 20, "ENSBTAT00000080603": 1, "A0A3Q1MD45": 20, "A0A3Q1MG36": 20, "ENSBTAT00000082227": 1, "A0A3Q1MIV3": 20, "ENSBTAT00000081596": 1, "CHEBI:59080": 9, "species_1236727": 8, "Q3T0T7": 10, "ENSBTAT00000028280": 1, "A6QNT8": 16, "ENSBTAT00000043111": 2, "F1MV07": 19, "ENSBTAT00000004721": 2, "F1MVW5": 18, "ENSBTAT00000004831": 2, "species_10055805": 18, "reaction_10043659": 3, "species_10043655": 6, "species_10043580": 5, "species_10043657": 7, "reaction_10055819": 3, "species_10054858": 14, "species_10055813": 18, "reaction_10055821": 2, "species_10055781": 13, "species_10042061": 14, "reaction_10087807": 3, "species_10055472": 17, "Q2NL04": 4, "ENSBTAT00000022386": 4, "Q5E9F1": 5, "ENSBTAT00000068015": 5, "A5D7J6": 4, "ENSBTAT00000020111": 4, "F1MVY8": 7, "ENSBTAT00000011787": 1, "E1BJS0": 7, "ENSBTAT00000080751": 1, "species_983033": 2, "species_10055474": 18, "reaction_10054866": 3, "species_10054864": 14, "species_10054862": 2, "reaction_10055444": 7, "species_983032": 2, "species_983034": 2, "species_10055441": 4, "reaction_10055460": 4, "species_8943716": 1, "species_10055457": 2, "ENSBTAT00000078466": 1, "reaction_10055783": 2, "species_10055715": 12, "reaction_10039485": 5, "species_10036954": 8, "F1N2V3": 18, "ENSBTAT00000026624": 1, "E1BA29": 18, "ENSBTAT00000016160": 1, "species_10037043": 5, "species_10036952": 4, "reaction_10037641": 3, "species_10037609": 3, "ENSBTAT00000042737": 5, "species_10037611": 4, "species_10037638": 8, "Q2LGB8": 18, "ENSBTAT00000075852": 2, "reaction_10037731": 2, "species_10037729": 3, "species_10037269": 6, "reaction_10037618": 3, "species_10037615": 3, "ENSBTAT00000013262": 1, "reaction_10038007": 3, "species_10038004": 2, "ENSBTAT00000007950": 2, "reaction_10049615": 3, "species_10046048": 2, "ENSBTAT00000008619": 2, "species_444210": 7, "CHEBI:17120": 4, "CHEBI:31011": 6, "species_76179": 9, "species_2022890": 10, "CHEBI:30768": 8, "species_10046050": 8, "B9VJV9": 4, "reaction_10049617": 3, "species_400427": 7, "species_426576": 10, "CHEBI:50122": 4, "species_33549": 6, "CHEBI:16196": 8, "CHEBI:42504": 4, "species_10046042": 3, "ENSBTAT00000063172": 2, "species_10046044": 9, "G3MZT6": 4, "reaction_10049585": 3, "species_10046054": 2, "ENSBTAT00000053502": 2, "species_444074": 6, "species_10046056": 7, "B9VJW0": 4, "reaction_10067360": 3, "species_3296298": 4, "species_10046489": 2, "ENSBTAT00000019274": 2, "species_10046491": 3, "F1N1J4": 4, "reaction_10041453": 3, "species_10041447": 2, "ENSBTAT00000040219": 2, "species_10041443": 4, "species_10041451": 3, "F1MHP5": 2, "reaction_10041463": 3, "species_10041457": 4, "ENSBTAT00000001038": 2, "species_10041461": 3, "F1MWF1": 18, "reaction_10040328": 3, "species_10040231": 12, "species_10040245": 8, "E1BBE2": 51, "ENSBTAT00000013571": 1, "A0A3Q1M7J4": 38, "ENSBTAT00000085129": 1, "E1BIN8": 55, "ENSBTAT00000029015": 4, "F1MEV4": 38, "ENSBTAT00000024140": 1, "E1BDM2": 28, "ENSBTAT00000005295": 1, "A0A3Q1MHB0": 32, "ENSBTAT00000067365": 2, "species_10040247": 11, "reaction_10040299": 4, "species_10040297": 8, "reaction_10040267": 5, "species_10040263": 2, "ENSBTAT00000067689": 2, "species_10040265": 2, "reaction_10040254": 4, "species_10040251": 8, "reaction_10040277": 4, "species_10040271": 7, "reaction_10043129": 4, "species_10043120": 12, "E1BEN9": 15, "ENSBTAT00000020414": 1, "E1BKL2": 5, "ENSBTAT00000035270": 1, "F1MHG3": 5, "ENSBTAT00000017163": 1, "A7MB15": 6, "ENSBTAT00000002720": 1, "G3N2W8": 6, "ENSBTAT00000027434": 1, "F1MMW6": 6, "ENSBTAT00000025757": 1, "F1N6M9": 6, "ENSBTAT00000014152": 1, "M5FK80": 18, "ENSBTAT00000087508": 2, "F1MIC3": 15, "ENSBTAT00000056446": 2, "species_10043126": 12, "F1N1K8": 2, "ENSBTAT00000007756": 1, "reaction_10071320": 3, "species_10041574": 4, "species_10041625": 3, "G3N174": 3, "ENSBTAT00000066153": 1, "E1BNA0": 3, "ENSBTAT00000010458": 1, "species_10041627": 7, "reaction_10059152": 3, "species_10043061": 3, "species_10043118": 9, "reaction_10083835": 5, "species_109276": 66, "species_10083828": 2, "ENSBTAT00000020127": 3, "species_10083830": 2, "species_10083832": 2, "species_10083733": 5, "ENSBTAT00000070524": 2, "reaction_10083741": 4, "species_10083739": 4, "F1MJH0": 2, "ENSBTAT00000025479": 2, "E1BGD9": 3, "species_10083737": 3, "species_351626": 33, "reaction_10083743": 3, "reaction_10083824": 3, "species_10083820": 2, "ENSBTAT00000081553": 2, "species_10083822": 3, "A0A3Q1NK79": 2, "reaction_10077943": 5, "species_171126": 4, "species_174675": 5, "species_6789319": 1, "species_10077940": 3, "E1BA50": 2, "ENSBTAT00000017778": 1, "G3MVZ9": 2, "ENSBTAT00000034704": 1, "reaction_10084466": 4, "species_10084458": 5, "E1BPU0": 3, "ENSBTAT00000061570": 1, "E1BNA8": 12, "ENSBTAT00000061122": 5, "species_10084463": 5, "reaction_10090009": 3, "species_10090005": 2, "A0A3Q1MD15": 3, "ENSBTAT00000079650": 1, "species_10089989": 4, "F1N7C7": 10, "ENSBTAT00000027446": 1, "species_10090007": 4, "reaction_10091896": 3, "species_10091892": 2, "F1MY55": 3, "ENSBTAT00000023513": 1, "species_10091882": 4, "species_10091894": 4, "reaction_10090011": 2, "species_10089969": 8, "reaction_10091884": 2, "reaction_10091916": 3, "species_10091900": 4, "species_10091912": 2, "A0A3Q1MZP2": 3, "ENSBTAT00000081390": 1, "species_10091914": 4, "reaction_10091902": 2, "reaction_10089985": 5, "species_10089965": 4, "species_10089982": 4, "F6RWK1": 10, "ENSBTAT00000043933": 1, "E1B801": 8, "ENSBTAT00000085833": 3, "A0A3Q1LWV5": 8, "ENSBTAT00000075058": 1, "reaction_10089972": 4, "reaction_10091878": 3, "species_10091874": 14, "E1BAJ4": 7, "ENSBTAT00000013713": 1, "A5D7A0": 3, "ENSBTAT00000044780": 1, "P79132": 3, "ENSBTAT00000023751": 1, "A0A3Q1LNG7": 3, "ENSBTAT00000075973": 4, "A0A3Q1LR88": 3, "ENSBTAT00000066654": 1, "A0JN43": 3, "ENSBTAT00000044160": 1, "E1BMN2": 5, "ENSBTAT00000061079": 1, "A0A3Q1LPT9": 5, "ENSBTAT00000077862": 2, "A0A3Q1NDE1": 3, "ENSBTAT00000086993": 1, "A0A3Q1MSB2": 3, "ENSBTAT00000070687": 1, "A0A3Q1LNB6": 3, "ENSBTAT00000070608": 1, "E1BHQ9": 3, "ENSBTAT00000047009": 1, "species_10091876": 16, "reaction_10057177": 3, "species_10057163": 5, "A0A3Q1MKB4": 35, "ENSBTAT00000084727": 2, "species_10035544": 5, "species_10057170": 6, "reaction_10057188": 3, "species_10057172": 6, "species_10057186": 8, "reaction_10057175": 4, "reaction_10057191": 5, "reaction_10083712": 5, "species_548819": 2, "species_8848483": 2, "species_429785": 10, "species_10083709": 2, "ENSBTAT00000087371": 2, "reaction_10083004": 4, "species_10082997": 7, "A0A3Q1MWA3": 10, "ENSBTAT00000083281": 1, "E1BMC4": 7, "A0A3Q1LV05": 10, "ENSBTAT00000074696": 1, "species_10083001": 5, "reaction_10083006": 3, "species_10082022": 3, "species_10082993": 3, "species_10082995": 5, "reaction_10082999": 3, "species_10082034": 4, "reaction_10049867": 5, "species_162860": 4, "species_449293": 2, "species_449283": 2, "species_10049864": 2, "ENSBTAT00000002836": 1, "reaction_10049851": 5, "species_449737": 1, "species_10049848": 2, "ENSBTAT00000003187": 1, "reaction_10049789": 6, "species_449229": 5, "species_449298": 1, "species_449311": 4, "species_449315": 2, "species_10049782": 2, "ENSBTAT00000032212": 1, "species_10049787": 5, "ENSBTAT00000000147": 1, "reaction_10049811": 6, "species_449312": 2, "species_449365": 2, "species_10049808": 2, "ENSBTAT00000064352": 1, "reaction_10049858": 6, "species_10049855": 3, "ENSBTAT00000052671": 1, "reaction_10082941": 5, "species_29410": 13, "species_29548": 2, "species_109402": 12, "species_10082938": 2, "ENSBTAT00000063951": 1, "reaction_10077816": 3, "species_6787618": 2, "species_6787646": 2, "species_10077813": 3, "A0A3Q1M2A1": 2, "ENSBTAT00000082106": 1, "reaction_10077800": 5, "species_6787542": 2, "species_742368": 2, "species_10077797": 2, "ENSBTAT00000055149": 1, "reaction_10077823": 4, "species_10077820": 2, "ENSBTAT00000015992": 1, "reaction_10077807": 5, "species_6787678": 1, "species_10077804": 2, "ENSBTAT00000085459": 1, "reaction_10077826": 6, "reaction_10049831": 3, "species_532562": 1, "species_532531": 1, "species_10049828": 3, "Q0VC17": 2, "ENSBTAT00000076692": 1, "Q3SZJ9": 2, "ENSBTAT00000001888": 1, "reaction_10069368": 5, "species_162756": 6, "species_110096": 7, "species_4085214": 2, "species_10069365": 3, "F1MIL9": 2, "ENSBTAT00000001520": 1, "reaction_10069320": 6, "species_4085225": 2, "species_29492": 2, "species_4085390": 2, "species_10069317": 2, "ENSBTAT00000025318": 1, "reaction_10069371": 5, "reaction_10069357": 5, "species_428633": 6, "species_10069354": 3, "A7YWM8": 2, "ENSBTAT00000000918": 1, "reaction_10069373": 5, "species_4088202": 5, "species_4086294": 2, "species_4086341": 2, "species_4087982": 3, "species_4086277": 3, "species_4088123": 4, "species_4088006": 3, "species_4086285": 4, "species_4086301": 2, "species_10059958": 3, "ENSBTAT00000027552": 1, "reaction_10069359": 5, "species_4088088": 3, "species_4088103": 3, "species_10059981": 3, "ENSBTAT00000036738": 1, "reaction_10048958": 5, "species_428040": 2, "species_428639": 2, "species_10048955": 2, "ENSBTAT00000061225": 1, "reaction_10069329": 5, "species_727815": 14, "species_727810": 23, "species_10069326": 4, "A0A3Q1N8K2": 2, "ENSBTAT00000074715": 1, "A0A3Q1LM08": 3, "ENSBTAT00000077891": 1, "A0A3Q1LZS9": 3, "ENSBTAT00000068182": 1, "reaction_10051554": 5, "species_4085435": 1, "species_109395": 3, "species_10051551": 2, "ENSBTAT00000018680": 1, "reaction_10069346": 5, "species_10069343": 6, "F1MXN8": 2, "ENSBTAT00000009616": 1, "G3N3B2": 2, "ENSBTAT00000063122": 2, "A0A452DJH9": 2, "ENSBTAT00000061027": 2, "A0A3Q1LRX1": 2, "ENSBTAT00000078008": 2, "F1N6V7": 2, "ENSBTAT00000034693": 1, "reaction_10069348": 5, "species_10054719": 7, "A0A3Q1LUC6": 3, "ENSBTAT00000078218": 2, "A0A3Q1MGH3": 3, "ENSBTAT00000075324": 2, "A5D960": 2, "ENSBTAT00000001538": 1, "Q6H8M9": 2, "ENSBTAT00000086395": 1, "reaction_10069382": 5, "species_10069379": 3, "A0A3Q1M347": 2, "ENSBTAT00000083430": 2, "A5D7T4": 2, "ENSBTAT00000070130": 1, "reaction_10069498": 5, "species_4419981": 1, "species_449221": 2, "reaction_10049818": 5, "species_449744": 1, "species_449299": 3, "species_10049815": 2, "ENSBTAT00000023834": 1, "reaction_10049804": 5, "species_110614": 9, "species_110094": 9, "species_10049801": 2, "ENSBTAT00000014016": 1, "reaction_10040933": 7, "species_191403": 1, "species_113528": 29, "species_191362": 4, "species_10040930": 2, "Q0P570": 2, "ENSBTAT00000015994": 1, "reaction_10049797": 5, "species_449222": 2, "species_10049794": 2, "ENSBTAT00000070574": 1, "reaction_10049844": 5, "species_10049841": 3, "F1MU60": 2, "ENSBTAT00000006020": 1, "A0A3Q1MW72": 2, "ENSBTAT00000076761": 1, "reaction_10049860": 6, "species_449371": 1, "reaction_10056074": 4, "species_975925": 3, "species_975910": 7, "species_981615": 3, "species_10056071": 3, "reaction_10056061": 4, "species_10054717": 2, "reaction_10054431": 4, "species_914003": 15, "species_981616": 1, "species_10054428": 3, "E1BNB2": 2, "ENSBTAT00000014809": 1, "A6QQ63": 2, "ENSBTAT00000049734": 1, "reaction_10054467": 4, "species_735682": 12, "species_981618": 1, "species_10054464": 8, "F6RH18": 2, "ENSBTAT00000047259": 1, "P08037": 7, "ENSBTAT00000020286": 2, "E1BCQ2": 2, "ENSBTAT00000061252": 1, "F6RJ53": 2, "ENSBTAT00000015761": 1, "reaction_10054418": 4, "species_10054415": 4, "reaction_10054438": 4, "species_981617": 1, "species_10054435": 2, "ENSBTAT00000084669": 1, "reaction_10054474": 4, "species_981613": 1, "species_10054471": 2, "ENSBTAT00000016591": 1, "reaction_10054411": 5, "species_975819": 1, "species_205687": 40, "species_975822": 1, "species_10054408": 2, "ENSBTAT00000048092": 1, "reaction_10076415": 5, "species_1605715": 32, "species_6784247": 1, "species_6784248": 1, "species_6784249": 1, "species_10076412": 2, "Q2KIM0": 4, "ENSBTAT00000042970": 1, "reaction_10077710": 5, "species_741440": 17, "species_10077694": 3, "species_10077703": 3, "species_742343": 17, "species_10077707": 2, "ENSBTAT00000064164": 1, "reaction_10077717": 5, "species_6786371": 1, "species_6786380": 1, "species_10077714": 2, "ENSBTAT00000082120": 1, "reaction_10076422": 5, "species_5693930": 1, "species_205683": 10, "species_5693933": 1, "species_205689": 10, "species_10076419": 5, "ENSBTAT00000000529": 2, "reaction_10076696": 3, "species_10076692": 2, "ENSBTAT00000078548": 2, "species_10043646": 3, "ENSBTAT00000009307": 2, "species_10076694": 3, "E1BL12": 2, "A0A3Q1LM15": 2, "reaction_10076586": 4, "species_10043590": 3, "A0A3Q1NDZ1": 15, "ENSBTAT00000083081": 1, "Q08DB5": 15, "ENSBTAT00000046561": 1, "species_10043594": 3, "species_10043592": 2, "species_10043596": 5, "reaction_10076590": 4, "species_10043539": 3, "ENSBTAT00000066705": 3, "species_10043651": 2, "species_10076588": 4, "A0A3Q1MMA1": 10, "reaction_10076706": 3, "species_10043622": 2, "ENSBTAT00000082647": 2, "species_10043618": 3, "A0A3Q1LUP7": 11, "ENSBTAT00000076684": 1, "A0A3Q1N355": 11, "ENSBTAT00000081836": 1, "species_10043624": 4, "G0T3G6": 10, "reaction_10076708": 3, "species_10043606": 3, "species_10043600": 2, "ENSBTAT00000025975": 2, "species_10043608": 4, "Q5BIN6": 10, "reaction_10076775": 4, "species_10043626": 12, "species_10043628": 15, "reaction_10076584": 4, "species_10076577": 26, "E1BKW5": 5, "ENSBTAT00000009785": 1, "A0A3Q1N147": 9, "ENSBTAT00000070415": 1, "Q3T086": 6, "ENSBTAT00000009288": 1, "A0A3Q1MRB3": 6, "ENSBTAT00000079685": 1, "Q17QI1": 8, "ENSBTAT00000065281": 1, "Q32L78": 6, "ENSBTAT00000019999": 1, "Q2TBL9": 6, "ENSBTAT00000010619": 1, "A0A3Q1M4U3": 6, "ENSBTAT00000087207": 1, "F1MSD6": 6, "ENSBTAT00000005590": 1, "Q3T0F2": 6, "ENSBTAT00000014509": 1, "species_10076581": 26, "reaction_10076635": 5, "species_10076618": 3, "species_10043653": 3, "species_10076632": 4, "E1BN43": 2, "ENSBTAT00000034553": 1, "Q2KIC7": 2, "ENSBTAT00000010568": 1, "G3N214": 2, "ENSBTAT00000066016": 1, "reaction_10076778": 5, "species_10043642": 4, "reaction_10076698": 4, "species_10076575": 9, "species_10076493": 4, "species_10076537": 15, "reaction_10043649": 5, "reaction_10083377": 3, "species_10082020": 4, "species_10083373": 3, "ENSBTAT00000017725": 2, "species_10083375": 5, "Q2T9Q1": 2, "reaction_10076736": 6, "species_10076704": 15, "P41541": 7, "ENSBTAT00000022642": 1, "A0A3Q1LTM9": 6, "ENSBTAT00000084718": 1, "A0A3Q1M072": 6, "ENSBTAT00000084758": 1, "species_10076667": 5, "A0A3Q1MJE3": 3, "ENSBTAT00000082298": 1, "E1BG76": 3, "ENSBTAT00000046085": 1, "species_10076596": 4, "species_10076677": 6, "species_10076734": 11, "species_10076602": 4, "reaction_10076610": 4, "species_10076608": 28, "reaction_10083380": 3, "reaction_10082026": 4, "species_10082024": 6, "reaction_10082045": 4, "species_10082036": 8, "species_10082042": 6, "reaction_10082038": 3, "reaction_10053337": 4, "species_964831": 4, "CHEBI:60629": 2, "CHEBI:60628": 2, "CHEBI:60627": 2, "species_964752": 3, "species_964740": 5, "species_10053314": 6, "E1BNG2": 2, "ENSBTAT00000061143": 1, "A0A3Q1MKX0": 2, "ENSBTAT00000072527": 1, "E1B7B0": 2, "ENSBTAT00000061594": 1, "reaction_10053339": 4, "species_964828": 1, "reaction_10053317": 4, "species_915149": 2, "reaction_10053324": 4, "species_964754": 1, "species_964744": 1, "species_964746": 2, "species_10053321": 2, "ENSBTAT00000006614": 1, "reaction_10053331": 5, "species_964837": 1, "species_10053328": 2, "ENSBTAT00000066191": 1, "reaction_10084373": 3, "species_8855720": 2, "species_10084369": 3, "Q32KM0": 3, "ENSBTAT00000016010": 1, "F1ME82": 3, "ENSBTAT00000035098": 1, "species_10084371": 4, "reaction_10056058": 2, "species_10056054": 4, "species_10056056": 9, "reaction_10089391": 2, "species_10089384": 2, "Q02372": 7, "ENSBTAT00000000100": 1, "species_10089388": 2, "ENSBTAT00000046212": 1, "reaction_10056912": 2, "species_10056833": 5, "species_1236715": 5, "E1BB51": 5, "ENSBTAT00000005993": 1, "A0A3S5ZP99": 5, "ENSBTAT00000011333": 1, "species_10056803": 5, "reaction_10056835": 2, "species_10056819": 4, "reaction_10056805": 3, "species_10056801": 3, "reaction_10087823": 5, "species_10084863": 8, "species_10087813": 3, "species_10087809": 2, "species_10087821": 2, "species_10087819": 3, "reaction_10084865": 6, "species_10084853": 2, "species_10084851": 3, "species_10084861": 3, "species_10076669": 3, "species_10084859": 4, "reaction_10084867": 8, "species_10055470": 2, "species_10055468": 2, "reaction_10056982": 2, "species_10056980": 11, "reaction_10056910": 4, "species_1236722": 1, "species_8943711": 1, "species_10056907": 12, "A0A3Q1MAQ4": 3, "ENSBTAT00000080071": 1, "reaction_10056914": 2, "species_10056901": 13, "reaction_10056903": 3, "species_10056899": 11, "reaction_10057004": 6, "species_1236709": 2, "species_2000347": 1, "species_2000345": 2, "species_2000349": 1, "species_2000348": 1, "species_10057001": 7, "O46521": 10, "ENSBTAT00000067849": 1, "A0A452DHY1": 10, "ENSBTAT00000004279": 1, "A0A3Q1MKI4": 9, "ENSBTAT00000084691": 1, "A0A3Q1MTW8": 10, "ENSBTAT00000076657": 1, "reaction_10041962": 3, "species_198852": 1, "species_198827": 2, "species_10041959": 2, "ENSBTAT00000042889": 2, "reaction_10041955": 5, "species_198816": 2, "species_111745": 11, "species_10041952": 2, "E1BED9": 3, "ENSBTAT00000005211": 1, "reaction_10041975": 5, "species_198836": 6, "species_10041972": 3, "E1BI45": 2, "ENSBTAT00000010823": 1, "E1BP61": 2, "ENSBTAT00000083275": 1, "reaction_10083656": 2, "species_10083480": 17, "species_10083654": 4, "reaction_10083672": 5, "species_10083662": 4, "Q29RQ2": 2, "ENSBTAT00000016581": 4, "species_10083669": 3, "reaction_10083676": 2, "species_10083674": 2, "reaction_10083664": 3, "species_10083660": 2, "reaction_10037748": 4, "species_140356": 13, "species_140357": 4, "species_10037745": 5, "A0A452DI94": 3, "ENSBTAT00000008833": 1, "CHEBI:26355": 5, "reaction_10037751": 6, "species_76342": 2, "species_30138": 3, "reaction_10063448": 8, "species_2046066": 6, "species_2046060": 2, "species_2046048": 2, "species_162743": 9, "species_159751": 7, "species_10051239": 3, "ENSBTAT00000074314": 2, "reaction_10063450": 7, "species_194697": 6, "species_2046063": 2, "species_194653": 6, "species_2046042": 2, "species_10063417": 4, "ENSBTAT00000020610": 1, "reaction_10063452": 7, "species_2046050": 2, "reaction_10063454": 7, "species_211579": 5, "species_2046044": 3, "species_2046064": 2, "species_2046049": 2, "species_10063422": 4, "A0A3Q1LWT4": 3, "ENSBTAT00000078831": 1, "reaction_10063442": 7, "species_2046045": 2, "species_2046053": 2, "species_10063434": 3, "ENSBTAT00000082100": 1, "reaction_10063413": 8, "species_10063410": 4, "Q2KJD9": 3, "ENSBTAT00000004358": 1, "A4FUF2": 3, "reaction_10063444": 6, "species_5228339": 1, "species_2046055": 1, "species_211606": 3, "species_10046702": 3, "ENSBTAT00000027382": 2, "reaction_10063446": 9, "species_10051249": 6, "E1BBR7": 3, "ENSBTAT00000020842": 1, "reaction_10063437": 7, "species_2046051": 2, "species_2046059": 2, "reaction_10063420": 7, "species_2046062": 2, "species_2046052": 2, "reaction_10063425": 7, "species_2046056": 6, "reaction_10063456": 9, "species_2046057": 2, "reaction_10063440": 9, "species_2046065": 1, "reaction_10063570": 5, "species_141343": 7, "species_2066765": 2, "species_193514": 8, "species_2066763": 1, "species_10041305": 4, "ENSBTAT00000074004": 2, "reaction_10063573": 5, "species_2066762": 1, "species_353123": 4, "species_10047050": 3, "ENSBTAT00000024335": 2, "reaction_10063428": 6, "species_2046054": 1, "species_2046047": 1, "reaction_10063430": 9, "reaction_10033912": 13, "species_70843": 3, "species_71019": 4, "species_10033909": 4, "A0A3Q1N969": 4, "ENSBTAT00000086761": 1, "A0A452DIR0": 4, "ENSBTAT00000020252": 1, "reaction_10033896": 5, "species_71009": 3, "species_10033893": 2, "ENSBTAT00000049741": 1, "reaction_10033889": 3, "species_70958": 3, "species_10033884": 5, "species_3159297": 3, "Q0III1": 3, "ENSBTAT00000076678": 1, "A6QQI8": 3, "ENSBTAT00000029806": 1, "reaction_10075631": 5, "species_5690540": 3, "CHEBI:33184": 3, "CHEBI:61907": 3, "species_5690519": 3, "species_30495": 4, "CHEBI:59554": 3, "species_10075628": 5, "A6QQA9": 3, "ENSBTAT00000074250": 2, "F1N234": 2, "E1BAC0": 2, "ENSBTAT00000000922": 1, "reaction_10036029": 11, "species_77330": 2, "species_77328": 2, "species_10036009": 6, "A0A3Q1LS03": 2, "ENSBTAT00000054475": 1, "reaction_10036038": 9, "species_77337": 2, "species_77332": 2, "species_10036035": 4, "Q3SZB4": 2, "ENSBTAT00000033470": 1, "reaction_10036027": 11, "species_77322": 2, "species_77320": 2, "reaction_10036040": 11, "species_77341": 2, "species_77339": 2, "reaction_10036042": 9, "species_77308": 2, "species_77343": 3, "reaction_10036012": 11, "species_77252": 2, "species_77253": 2, "reaction_10036021": 9, "species_77261": 2, "species_77255": 2, "species_10036018": 3, "Q08D92": 2, "ENSBTAT00000013988": 1, "reaction_10036025": 11, "species_77251": 2, "species_73871": 6, "reaction_10036023": 9, "species_77272": 2, "species_77273": 2, "reaction_10086403": 5, "species_977314": 1, "species_10086393": 2, "ENSBTAT00000008382": 4, "species_10086396": 2, "species_10086400": 2, "ENSBTAT00000003130": 1, "reaction_10036664": 3, "species_109994": 1, "species_10036215": 3, "F1MTT7": 2, "ENSBTAT00000013144": 1, "reaction_10036218": 3, "species_77358": 1, "species_77360": 1, "reaction_10036220": 5, "species_109986": 1, "species_109990": 1, "reaction_10075607": 6, "species_5690044": 3, "species_5690064": 3, "species_10075600": 5, "F6QGE6": 2, "ENSBTAT00000021731": 1, "A0A3Q1MI69": 2, "ENSBTAT00000075163": 1, "E1BNW7": 2, "ENSBTAT00000014753": 1, "species_10075605": 3, "ENSBTAT00000024898": 2, "reaction_10076806": 5, "species_5695946": 1, "species_5695949": 1, "species_10076803": 2, "ENSBTAT00000080862": 1, "reaction_10042860": 6, "species_549207": 2, "species_200993": 11, "species_201034": 2, "species_10042857": 3, "A0A3Q1LMV3": 2, "ENSBTAT00000069870": 1, "Q58DK1": 2, "ENSBTAT00000021357": 1, "species_29508": 3, "reaction_10042897": 5, "species_201023": 1, "species_201050": 1, "species_10042894": 2, "ENSBTAT00000000217": 1, "reaction_10085185": 3, "species_10085181": 2, "ENSBTAT00000015490": 2, "species_10085177": 2, "ENSBTAT00000015231": 2, "species_10085183": 3, "Q08E46": 2, "A0A3S5ZPK2": 2, "reaction_10077001": 5, "species_192172": 1, "species_5696426": 1, "species_5696412": 1, "species_10076998": 2, "ENSBTAT00000025081": 1, "reaction_10044657": 5, "species_266013": 10, "species_266074": 9, "species_10044654": 3, "F1MYJ3": 2, "ENSBTAT00000023658": 1, "G3N2D8": 3, "ENSBTAT00000063999": 1, "reaction_10064482": 8, "species_2142740": 2, "reaction_10064581": 3, "species_265281": 1, "species_2142772": 1, "species_10064560": 3, "P27479": 4, "ENSBTAT00000015911": 2, "species_71067": 33, "reaction_10064503": 8, "species_2161582": 1, "reaction_10064578": 4, "species_29768": 8, "species_2142718": 1, "species_10064575": 4, "F1MXW0": 2, "ENSBTAT00000011570": 1, "reaction_10064546": 8, "species_2142738": 1, "species_10064543": 8, "F1MNI5": 4, "ENSBTAT00000018774": 1, "reaction_10064554": 6, "species_2142790": 1, "species_2142716": 1, "species_10064551": 3, "ENSBTAT00000070793": 2, "reaction_10064565": 4, "species_2142811": 2, "species_10064562": 4, "F1MFA8": 3, "ENSBTAT00000029240": 1, "reaction_10064567": 6, "species_2142678": 1, "reaction_10064534": 3, "species_2142745": 1, "species_10064488": 10, "reaction_10076382": 5, "species_5693754": 6, "species_1498751": 4, "species_10076379": 2, "ENSBTAT00000071864": 1, "reaction_10064506": 4, "species_2162031": 3, "CHEBI:36190": 1, "CHEBI:34784": 1, "reaction_10086336": 4, "species_8932801": 1, "species_8932804": 1, "species_10086333": 4, "Q1JQD3": 2, "ENSBTAT00000049076": 1, "Q2KIW1": 2, "ENSBTAT00000020790": 1, "reaction_10064521": 8, "species_2142739": 2, "species_10064518": 6, "F1MM10": 7, "ENSBTAT00000061300": 2, "F1MHN9": 10, "ENSBTAT00000000094": 2, "F1MNG1": 6, "ENSBTAT00000075887": 2, "F1N3N3": 4, "ENSBTAT00000051914": 1, "M0QW09": 4, "ENSBTAT00000018202": 1, "reaction_10064526": 8, "species_2161753": 4, "CHEBI:34130": 2, "CHEBI:34490": 2, "CHEBI:34157": 2, "species_10064523": 8, "A0A3S5ZP79": 6, "ENSBTAT00000027159": 1, "F1MEU8": 5, "ENSBTAT00000008918": 1, "reaction_10065210": 8, "species_10065205": 9, "species_549282": 6, "species_10065208": 4, "reaction_10064442": 6, "species_265283": 4, "species_879535": 4, "species_10041165": 16, "E1BP71": 4, "ENSBTAT00000039350": 1, "M0QW21": 3, "ENSBTAT00000028488": 1, "E1BG58": 3, "ENSBTAT00000038997": 2, "M0QW25": 3, "ENSBTAT00000030566": 1, "M0QW04": 3, "M0QW14": 3, "ENSBTAT00000023326": 2, "F1MT58": 3, "ENSBTAT00000055749": 1, "Q3ZBG2": 3, "ENSBTAT00000023297": 1, "G3X704": 3, "F1MK69": 3, "ENSBTAT00000056823": 1, "P52897": 3, "ENSBTAT00000024086": 2, "F1MNC0": 3, "ENSBTAT00000039362": 1, "P52898": 3, "reaction_10064474": 3, "species_265287": 3, "species_10064471": 3, "Q95L14": 2, "ENSBTAT00000025912": 1, "reaction_10065213": 3, "species_9716714": 1, "reaction_10064445": 6, "species_879629": 2, "species_2142710": 1, "reaction_10064479": 3, "species_10064476": 3, "F1MGZ9": 3, "ENSBTAT00000022700": 1, "reaction_10064465": 6, "species_10064462": 3, "A0A3Q1NG39": 2, "ENSBTAT00000084736": 1, "Q3T0T9": 2, "ENSBTAT00000043292": 1, "reaction_10044599": 3, "species_10044596": 3, "A0A3Q1LFK5": 4, "ENSBTAT00000071669": 1, "A0A452DIU3": 4, "ENSBTAT00000023908": 1, "reaction_10065225": 4, "species_2314693": 2, "species_2314690": 2, "reaction_10065216": 4, "reaction_10064452": 3, "species_2161634": 1, "species_10064449": 2, "ENSBTAT00000020065": 1, "reaction_10065223": 4, "species_10065221": 3, "reaction_10064511": 8, "species_2161639": 4, "CHEBI:63995": 1, "CHEBI:63994": 1, "CHEBI:63579": 1, "species_10064508": 4, "reaction_10064531": 8, "species_2142780": 1, "species_10064528": 10, "F1N3I8": 4, "ENSBTAT00000021785": 1, "F1MFI9": 3, "ENSBTAT00000017246": 2, "reaction_10064516": 8, "species_2142836": 1, "species_10064513": 8, "reaction_10047033": 5, "species_113535": 9, "species_389893": 3, "species_113575": 8, "species_389894": 2, "species_10047030": 4, "A0A3Q1LWZ7": 2, "ENSBTAT00000082299": 1, "F1MRF5": 3, "ENSBTAT00000005472": 1, "reaction_10047056": 5, "species_390305": 1, "reaction_10047042": 5, "species_10047039": 3, "A4IFA4": 2, "ENSBTAT00000044120": 1, "reaction_10047044": 3, "species_389569": 2, "species_10041183": 6, "ENSBTAT00000029075": 1, "reaction_10077835": 5, "species_6787810": 1, "species_6787814": 1, "species_10077832": 2, "Q3ZBW2": 2, "ENSBTAT00000000134": 1, "reaction_10077784": 6, "species_193465": 5, "species_6786723": 1, "species_113602": 3, "species_6786715": 1, "species_389556": 3, "species_10077781": 2, "ENSBTAT00000072961": 1, "reaction_10075576": 5, "species_5690520": 3, "species_5690539": 3, "species_10075573": 4, "A0A3Q1N6L4": 2, "A0A3S5ZPS3": 2, "ENSBTAT00000003683": 1, "E1BBG0": 2, "ENSBTAT00000013568": 1, "reaction_10047053": 5, "species_390241": 1, "species_390246": 1, "reaction_10082880": 3, "species_6809801": 1, "species_6809800": 1, "species_10082877": 2, "A0A3Q1LP28": 2, "ENSBTAT00000083505": 1, "reaction_10054592": 4, "species_977323": 1, "species_389536": 2, "species_10054589": 2, "ENSBTAT00000005562": 1, "reaction_10047058": 3, "species_390394": 1, "species_390260": 1, "species_10046704": 3, "Q2KJ57": 4, "reaction_10082889": 6, "species_6809811": 1, "species_389615": 3, "species_10082886": 2, "G3X6L7": 2, "ENSBTAT00000008962": 1, "reaction_10047001": 7, "species_389537": 1, "species_389594": 1, "species_389583": 1, "species_10046998": 3, "O18778": 4, "ENSBTAT00000010126": 1, "reaction_10046984": 6, "species_389636": 1, "species_192307": 1, "species_6811612": 2, "species_192305": 2, "species_10046981": 2, "A0A3Q1LJ52": 5, "ENSBTAT00000070862": 1, "reaction_10046989": 7, "species_389596": 1, "species_389573": 2, "species_389593": 2, "species_389620": 3, "species_10046986": 3, "ENSBTAT00000078122": 3, "reaction_10046992": 7, "reaction_10083389": 8, "species_428139": 2, "species_4085415": 1, "species_4085425": 1, "species_5690558": 1, "species_10083386": 2, "Q2KIA4": 2, "ENSBTAT00000025820": 1, "reaction_10051261": 6, "species_548812": 1, "species_10051258": 3, "A6QNQ7": 2, "ENSBTAT00000067475": 1, "reaction_10042961": 8, "species_3632881": 5, "species_10042958": 5, "Q1LZF6": 2, "ENSBTAT00000064114": 1, "A0A3Q1LPX2": 2, "ENSBTAT00000080693": 1, "F1MEX9": 2, "ENSBTAT00000022939": 2, "reaction_10074353": 4, "species_5676631": 1, "species_5676634": 1, "species_10074350": 2, "F1MXJ1": 2, "ENSBTAT00000046976": 1, "reaction_10051252": 6, "species_548816": 1, "reaction_10044985": 7, "species_352186": 5, "species_352036": 12, "species_29612": 12, "species_29642": 9, "species_352169": 5, "species_10044982": 2, "ENSBTAT00000011214": 1, "reaction_10044955": 3, "species_352101": 7, "CHEBI:58045": 9, "CHEBI:57427": 11, "species_174390": 13, "species_351993": 7, "species_29702": 10, "species_352114": 7, "species_10044952": 2, "ENSBTAT00000072259": 1, "reaction_10045501": 3, "species_375765": 4, "CHEBI:32551": 10, "species_113530": 14, "species_375781": 4, "species_10045498": 2, "ENSBTAT00000019060": 1, "reaction_10044978": 3, "species_352161": 4, "species_352006": 7, "species_352030": 6, "species_352139": 4, "species_10044975": 2, "ENSBTAT00000012176": 1, "reaction_10044948": 5, "species_352051": 13, "species_379717": 7, "species_351990": 5, "species_111707": 15, "species_379732": 9, "CHEBI:18240": 2, "species_352048": 13, "species_10044945": 2, "ENSBTAT00000076418": 1, "reaction_10045494": 3, "species_10045491": 2, "ENSBTAT00000009736": 1, "reaction_10088905": 3, "species_8959777": 7, "CHEBI:28229": 2, "species_113586": 3, "CHEBI:27747": 2, "species_8959775": 7, "species_10088902": 2, "ENSBTAT00000018163": 1, "reaction_10085384": 3, "species_352033": 2, "species_113538": 3, "species_10085378": 3, "ENSBTAT00000011246": 1, "reaction_10045480": 5, "species_375458": 13, "species_29424": 15, "species_375481": 13, "species_10045477": 2, "ENSBTAT00000064818": 1, "reaction_10044971": 3, "species_352128": 3, "species_352135": 3, "species_10044968": 2, "ENSBTAT00000070473": 1, "reaction_10044941": 7, "species_188972": 19, "species_352007": 5, "species_73590": 6, "species_428571": 7, "species_352015": 3, "CHEBI:48950": 2, "species_351982": 5, "species_10044938": 2, "ENSBTAT00000067153": 1, "reaction_10045487": 7, "species_375468": 14, "species_375459": 14, "species_10045484": 2, "ENSBTAT00000083685": 1, "reaction_10045473": 5, "species_375409": 3, "species_375414": 3, "species_10045470": 2, "ENSBTAT00000027731": 1, "reaction_10044962": 3, "species_10044959": 2, "ENSBTAT00000015260": 1, "reaction_10044964": 5, "species_352091": 10, "species_352088": 10, "species_10044458": 3, "ENSBTAT00000014749": 1, "reaction_10044934": 3, "species_266029": 2, "species_10044931": 2, "ENSBTAT00000016676": 1, "reaction_10039272": 3, "species_10039264": 3, "A0A3Q1LP06": 17, "ENSBTAT00000076924": 1, "species_10039258": 3, "ENSBTAT00000067057": 2, "species_10039266": 4, "A0A3Q1MJ18": 13, "reaction_10040684": 2, "species_10039569": 3, "species_10039684": 4, "reaction_10039270": 3, "species_10039268": 3, "reaction_10088473": 5, "species_10088246": 72, "A0A3Q1N5X6": 4, "ENSBTAT00000080120": 1, "P11116": 3, "ENSBTAT00000020080": 1, "A6QP39": 3, "ENSBTAT00000000202": 1, "E1BG36": 3, "ENSBTAT00000009958": 1, "E1BG25": 3, "ENSBTAT00000046533": 1, "A4FUZ9": 3, "ENSBTAT00000026336": 1, "A0A3Q1MS36": 3, "ENSBTAT00000076629": 1, "A0A452DII7": 3, "ENSBTAT00000016252": 1, "F1N5H2": 5, "ENSBTAT00000002297": 1, "F1MKR5": 3, "ENSBTAT00000013661": 1, "A0A3Q1N3Y2": 3, "ENSBTAT00000073105": 1, "Q3ZBZ6": 21, "ENSBTAT00000027192": 1, "E1BLA8": 3, "ENSBTAT00000044756": 1, "Q05717": 3, "ENSBTAT00000078855": 1, "P20959": 3, "ENSBTAT00000053426": 1, "P24591": 4, "ENSBTAT00000064194": 2, "Q95M18": 5, "ENSBTAT00000004364": 2, "P26892": 19, "ENSBTAT00000019865": 2, "F1MPP2": 3, "ENSBTAT00000025803": 1, "F1MI67": 5, "ENSBTAT00000025557": 1, "F6RJ01": 5, "ENSBTAT00000027753": 1, "Q2KJH1": 5, "ENSBTAT00000004992": 1, "G3X6N3": 10, "Q6PX77": 3, "ENSBTAT00000064918": 1, "E1B8P3": 3, "ENSBTAT00000002384": 1, "A0A452DJ03": 3, "ENSBTAT00000028372": 1, "A0A5H1ZRH6": 5, "ENSBTAT00000028238": 1, "E1BH06": 12, "ENSBTAT00000009019": 1, "F1MVK1": 12, "ENSBTAT00000045468": 1, "F1MEA1": 3, "ENSBTAT00000024433": 1, "A0A3Q1LMK4": 5, "ENSBTAT00000076179": 2, "G3N348": 3, "ENSBTAT00000082028": 1, "F1ME65": 9, "ENSBTAT00000015804": 3, "F1MAZ4": 3, "ENSBTAT00000005810": 1, "A0A3Q1LRR3": 3, "ENSBTAT00000074422": 1, "P01035": 7, "ENSBTAT00000000790": 1, "F6QH94": 3, "ENSBTAT00000002508": 1, "A0A452DHZ5": 3, "ENSBTAT00000003073": 1, "Q1LZE9": 3, "ENSBTAT00000020194": 1, "P01211": 7, "ENSBTAT00000087134": 1, "A0A3Q1NJR8": 7, "ENSBTAT00000071014": 2, "G3N2L2": 3, "ENSBTAT00000063521": 1, "A0A3Q1MEX5": 3, "ENSBTAT00000072231": 1, "A6QPR4": 3, "ENSBTAT00000044682": 2, "G3N2W6": 3, "ENSBTAT00000065790": 2, "A0A3Q1NAS1": 3, "ENSBTAT00000074235": 1, "A6QQR3": 3, "G3X724": 3, "A0A3Q1NIX0": 3, "ENSBTAT00000078756": 1, "E1BHJ7": 3, "ENSBTAT00000016190": 1, "A0A3Q1MB94": 3, "ENSBTAT00000069263": 1, "A6QP86": 3, "ENSBTAT00000054074": 1, "F6QSG5": 3, "ENSBTAT00000056456": 1, "A0A3Q1LIS3": 3, "ENSBTAT00000085388": 1, "P81644": 3, "ENSBTAT00000012138": 1, "F1MD94": 3, "ENSBTAT00000027836": 1, "A0A3Q1LVS2": 10, "ENSBTAT00000069650": 1, "A0A3Q1MY30": 7, "ENSBTAT00000082437": 1, "P02817": 3, "ENSBTAT00000016034": 1, "E1BDK6": 7, "ENSBTAT00000057452": 1, "E1BJF8": 4, "ENSBTAT00000022706": 1, "F1MD77": 7, "ENSBTAT00000015881": 1, "species_8931885": 1, "species_10088464": 72, "species_8931884": 1, "species_10088471": 3, "F1MJW4": 2, "ENSBTAT00000001439": 1, "reaction_10046621": 3, "species_10046613": 3, "species_10046617": 2, "species_10046619": 3, "reaction_10068959": 5, "species_10068951": 2, "ENSBTAT00000064363": 2, "species_10068947": 2, "ENSBTAT00000074434": 2, "species_10068943": 2, "ENSBTAT00000002664": 2, "species_10068955": 2, "ENSBTAT00000018360": 2, "species_10068957": 5, "G3X746": 2, "Q2KIG1": 2, "A0A3Q1NMK6": 2, "G3N0Y4": 2, "reaction_10061480": 4, "species_10061477": 6, "F1MCQ7": 17, "ENSBTAT00000029056": 1, "species_10057121": 5, "reaction_10061469": 4, "species_10061466": 6, "species_10057130": 5, "reaction_10057692": 3, "species_10057688": 5, "species_10057690": 8, "reaction_10057695": 5, "reaction_10086415": 3, "species_10084846": 3, "ENSBTAT00000068950": 2, "species_10086408": 2, "species_10086413": 3, "A0A3Q1M0B4": 2, "reaction_10057139": 4, "species_10057134": 6, "species_10057136": 6, "reaction_10083483": 5, "species_10083475": 7, "species_10057132": 9, "reaction_10083477": 3, "species_10083473": 3, "reaction_10057700": 5, "species_10057697": 6, "reaction_10077601": 3, "species_10077597": 2, "ENSBTAT00000085928": 2, "species_10077599": 7, "A0A3Q1N5P3": 3, "reaction_10077605": 3, "species_10073537": 6, "A0A3Q1LUD9": 15, "ENSBTAT00000083004": 1, "species_10077603": 9, "reaction_10084849": 5, "species_10084842": 5, "reaction_10061458": 3, "species_10061454": 2, "ENSBTAT00000069379": 2, "species_10061456": 6, "Q58D16": 2, "reaction_10057740": 4, "species_10057737": 7, "Q2KI91": 5, "ENSBTAT00000087037": 2, "Q0IIM6": 2, "ENSBTAT00000033814": 2, "species_10055232": 6, "species_10057726": 3, "reaction_10057742": 3, "species_10057709": 6, "reaction_10057744": 3, "species_10057066": 2, "ENSBTAT00000013790": 2, "species_10057714": 4, "A6QR62": 3, "reaction_10057712": 3, "reaction_10057719": 4, "species_10057716": 5, "reaction_10057735": 4, "species_10057730": 2, "species_10057732": 4, "reaction_10061492": 5, "species_10061489": 2, "reaction_10066602": 5, "species_3165253": 1, "species_196931": 3, "species_10066599": 3, "A0A3Q1N6I5": 2, "ENSBTAT00000083852": 1, "Q5E9R1": 2, "ENSBTAT00000084768": 1, "species_73524": 11, "species_29386": 3, "reaction_10041772": 5, "species_10041769": 2, "ENSBTAT00000081315": 1, "reaction_10041790": 5, "species_10041787": 2, "F1MNS5": 2, "ENSBTAT00000061365": 1, "reaction_10041781": 5, "species_10041778": 2, "E1B8A0": 2, "ENSBTAT00000006339": 1, "reaction_10041799": 5, "species_10041796": 3, "F6R223": 2, "ENSBTAT00000025762": 1, "reaction_10056185": 5, "species_10056174": 8, "A0A3Q1ME65": 43, "ENSBTAT00000084342": 7, "E1BJQ3": 18, "ENSBTAT00000024587": 3, "species_10056180": 9, "species_10056183": 8, "Q9BEG9": 13, "ENSBTAT00000011106": 2, "reaction_10056123": 2, "species_10056119": 6, "species_10056121": 7, "reaction_10056188": 3, "species_10056166": 10, "species_10051764": 3, "reaction_10056127": 4, "species_10056113": 3, "species_10056094": 3, "species_10056115": 4, "species_10056125": 3, "reaction_10056176": 3, "species_10046556": 5, "reaction_10056178": 2, "species_10051766": 5, "species_10052345": 4, "reaction_10056201": 3, "species_10056190": 9, "reaction_10056168": 4, "species_10056149": 7, "reaction_10056170": 4, "reaction_10056205": 4, "species_10056203": 7, "reaction_10056172": 2, "reaction_10056207": 3, "species_10051731": 3, "reaction_10056110": 4, "species_10049958": 7, "species_10056100": 5, "species_10056104": 6, "species_10056108": 5, "reaction_10091747": 3, "species_9715042": 1, "reaction_10056130": 3, "species_10056106": 2, "reaction_10056194": 3, "species_10040359": 10, "ENSBTAT00000072559": 4, "species_10056192": 8, "A0A3Q1LN00": 32, "reaction_10056132": 3, "species_10056117": 6, "reaction_10056199": 4, "species_10056196": 7, "reaction_10056102": 3, "species_10056098": 2, "reaction_10087338": 3, "species_10087334": 3, "F1MWT5": 3, "ENSBTAT00000023970": 2, "E1BD32": 4, "ENSBTAT00000023975": 4, "species_10083514": 4, "ENSBTAT00000007489": 2, "species_10087336": 4, "F1N3K3": 4, "reaction_10083522": 4, "species_10083510": 4, "G3MX81": 3, "ENSBTAT00000065203": 1, "F1N2N4": 3, "ENSBTAT00000002696": 1, "F1MYY4": 3, "ENSBTAT00000045402": 1, "species_10083516": 5, "species_10083520": 2, "reaction_10050024": 6, "species_10050013": 2, "ENSBTAT00000072083": 6, "species_10050007": 3, "species_10050005": 3, "species_10050017": 2, "species_10050015": 2, "species_10050021": 2, "reaction_10050011": 3, "species_10050009": 3, "A0A3Q1MFA5": 5, "reaction_10050028": 2, "species_10050026": 5, "reaction_10089595": 3, "species_10087332": 3, "species_10089593": 3, "reaction_10089597": 4, "species_10037699": 4, "species_10039514": 4, "reaction_10089591": 3, "species_10089589": 2, "species_10089587": 2, "reaction_10089625": 2, "species_10089617": 3, "ENSBTAT00000029311": 6, "species_10089623": 2, "reaction_10089819": 2, "species_10089810": 4, "E1BLE5": 4, "species_10089816": 4, "reaction_10089615": 4, "species_10053189": 3, "ENSBTAT00000023134": 3, "species_10089613": 2, "reaction_10083537": 3, "species_10083527": 2, "ENSBTAT00000001371": 2, "species_10083531": 3, "species_10083535": 3, "F1MJ29": 2, "reaction_10089843": 4, "species_10089814": 2, "reaction_10089621": 2, "species_10089619": 3, "reaction_10089812": 3, "reaction_10049721": 3, "species_10049717": 2, "ENSBTAT00000087066": 2, "species_10049713": 3, "F1ML75": 4, "ENSBTAT00000006938": 2, "Q2KIE7": 3, "ENSBTAT00000008322": 1, "species_10049719": 4, "A0A3Q1MKE9": 2, "reaction_10043867": 5, "species_10043854": 2, "ENSBTAT00000022183": 3, "species_10043858": 3, "species_10043864": 2, "ENSBTAT00000009995": 1, "reaction_10091757": 3, "species_9681804": 1, "species_10049707": 2, "species_10091755": 2, "reaction_10050428": 4, "species_10050418": 4, "Q1RMT8": 3, "ENSBTAT00000028115": 2, "A0A3Q1LQ14": 3, "ENSBTAT00000067567": 2, "species_10050425": 3, "reaction_10050420": 3, "species_10050416": 2, "species_10050412": 2, "reaction_10051095": 3, "species_10051091": 3, "A0A3Q1LPF2": 3, "ENSBTAT00000081015": 1, "species_10051093": 4, "reaction_10085017": 3, "species_10084951": 2, "ENSBTAT00000018087": 2, "species_10085013": 3, "P68432": 39, "ENSBTAT00000087179": 1, "P84227": 39, "ENSBTAT00000079615": 1, "species_10085015": 4, "F1MTQ0": 2, "reaction_10091731": 3, "species_10050577": 3, "ENSBTAT00000027857": 2, "species_9678772": 1, "species_10091729": 2, "E1BEL4": 11, "reaction_10089251": 4, "species_10089244": 4, "E1BPM3": 7, "ENSBTAT00000026608": 1, "G3X7G0": 5, "ENSBTAT00000026955": 1, "A0A3Q1M5G1": 4, "ENSBTAT00000072042": 2, "species_10089248": 4, "reaction_10089253": 3, "species_10089234": 2, "species_10089240": 3, "species_10089242": 4, "reaction_10087787": 2, "species_10087772": 4, "A0A3Q1MQM6": 3, "ENSBTAT00000074594": 2, "A0A3Q1LK84": 10, "ENSBTAT00000083936": 3, "species_10087785": 3, "reaction_10049946": 2, "species_10049938": 3, "A6QPV0": 15, "ENSBTAT00000017046": 1, "species_10049944": 5, "reaction_10087726": 4, "species_10087711": 9, "A5D7S4": 8, "ENSBTAT00000022524": 3, "species_10087723": 8, "reaction_10087774": 3, "species_10087770": 2, "species_10087768": 2, "reaction_10087793": 2, "species_10049962": 2, "species_10087791": 2, "reaction_10049970": 5, "species_10049964": 4, "species_10049966": 9, "species_10049968": 2, "reaction_10087671": 5, "species_10049940": 2, "reaction_10087783": 4, "reaction_10087766": 4, "species_10087736": 9, "species_10087734": 9, "reaction_10089321": 4, "species_10089313": 5, "species_10089319": 5, "reaction_10089329": 4, "species_10089325": 7, "species_10089327": 7, "reaction_10089331": 3, "species_10089323": 6, "reaction_10087763": 4, "species_10087752": 7, "species_10087760": 7, "reaction_10089333": 3, "species_10087758": 4, "reaction_10087780": 2, "species_10087776": 3, "species_10087778": 3, "reaction_10049928": 4, "species_10049924": 3, "F1MZJ0": 6, "ENSBTAT00000019945": 1, "species_10049904": 4, "F1MSN4": 7, "ENSBTAT00000005745": 1, "species_10049914": 3, "species_10049926": 7, "reaction_10087789": 2, "species_10087669": 3, "reaction_10087697": 4, "species_10087690": 9, "species_10087694": 8, "reaction_10088498": 3, "species_10087674": 2, "species_10087688": 7, "reaction_10051194": 2, "species_10051187": 4, "A0A3Q1LVP1": 3, "ENSBTAT00000084967": 2, "species_10051192": 3, "reaction_10051196": 3, "species_10047260": 2, "reaction_10050527": 3, "species_10050134": 2, "ENSBTAT00000074166": 2, "species_10049950": 6, "species_10050136": 3, "A0A3Q1LQZ1": 9, "reaction_10089736": 3, "species_10089732": 2, "ENSBTAT00000009944": 2, "species_10089734": 3, "F1MTF9": 2, "reaction_10089363": 2, "species_10089359": 2, "species_10089361": 2, "reaction_10050619": 3, "species_10050571": 3, "species_10050569": 9, "F1MXH7": 25, "ENSBTAT00000011947": 1, "A0A3Q1LK34": 19, "ENSBTAT00000085850": 1, "A0A3Q1MB14": 25, "ENSBTAT00000040022": 2, "P11052": 23, "ENSBTAT00000002054": 2, "species_10050617": 14, "A2VE30": 3, "ENSBTAT00000054113": 1, "reaction_10050623": 3, "species_10050621": 9, "reaction_10052254": 4, "species_10052252": 13, "reaction_10052337": 3, "species_10052333": 3, "E1BBJ7": 5, "ENSBTAT00000025510": 1, "A0A3Q1LJT8": 6, "ENSBTAT00000077857": 2, "species_10052335": 9, "reaction_10052343": 3, "species_10052339": 8, "A0A3Q1M739": 11, "ENSBTAT00000077529": 2, "species_10035485": 10, "species_10052341": 9, "reaction_10089291": 2, "species_10089255": 7, "Q28028": 7, "ENSBTAT00000084366": 2, "A0A3Q1M783": 7, "ENSBTAT00000083836": 2, "species_10089289": 6, "reaction_10089311": 3, "species_10089307": 1, "species_10089305": 8, "species_10089309": 8, "reaction_10089267": 4, "species_10089264": 6, "reaction_10089269": 3, "species_10050128": 2, "species_10050124": 2, "species_10050130": 3, "reaction_10089689": 3, "species_10089685": 4, "A6QL48": 5, "ENSBTAT00000076664": 2, "species_10077839": 3, "ENSBTAT00000016977": 2, "species_10089687": 4, "A7Z067": 3, "reaction_10089691": 3, "species_10089683": 2, "species_10049979": 3, "reaction_10090027": 3, "species_10090023": 2, "ENSBTAT00000069233": 2, "species_10050140": 3, "ENSBTAT00000017100": 2, "species_10090025": 3, "E1BGS4": 3, "A0A3Q1LYB4": 2, "reaction_10049983": 2, "species_10049981": 3, "reaction_10090031": 3, "species_10090029": 3, "reaction_10077843": 3, "species_10077841": 3, "reaction_10077945": 1, "species_10060767": 2, "reaction_10077723": 2, "species_10077719": 2, "ENSBTAT00000008311": 5, "species_10077721": 3, "F1MGJ4": 10, "reaction_10077870": 2, "species_10077866": 3, "species_10077868": 4, "reaction_10077633": 3, "species_10049908": 2, "species_10077629": 2, "ENSBTAT00000025754": 2, "species_10077631": 3, "G3X7E9": 2, "reaction_10077874": 2, "species_10077872": 3, "reaction_10077764": 2, "species_10077762": 2, "reaction_10052302": 3, "species_10052298": 5, "G3N016": 6, "ENSBTAT00000066024": 1, "E1BQ32": 6, "ENSBTAT00000007443": 1, "species_10039707": 3, "ENSBTAT00000066818": 2, "species_10052300": 5, "A0A3Q1LXN8": 3, "reaction_10052323": 3, "species_10052267": 4, "species_10052296": 3, "reaction_10052294": 3, "species_10052288": 8, "species_10052269": 4, "species_10052292": 4, "reaction_10051962": 3, "species_10051923": 8, "species_10051960": 7, "reaction_10051949": 4, "species_10051942": 5, "species_10051946": 5, "reaction_10052735": 2, "species_10052238": 9, "species_10052732": 8, "reaction_10051966": 2, "species_10051964": 6, "species_10051921": 8, "reaction_10052321": 3, "species_10037660": 2, "ENSBTAT00000000289": 3, "species_10052317": 6, "species_10052319": 7, "P63103": 15, "reaction_10051936": 5, "species_10051933": 6, "reaction_10052240": 3, "species_10047046": 4, "reaction_10051954": 4, "species_10051951": 6, "reaction_10052325": 3, "species_10050559": 2, "species_10050555": 2, "species_10050561": 4, "reaction_10052327": 3, "species_10051911": 3, "species_10051917": 5, "reaction_10089466": 4, "species_10089459": 4, "A0A3Q1M5P5": 12, "ENSBTAT00000066507": 2, "A6QNP0": 13, "ENSBTAT00000010919": 2, "species_10089463": 4, "reaction_10089530": 4, "species_10089527": 5, "G3MZC4": 6, "ENSBTAT00000063825": 1, "E1B7G0": 7, "ENSBTAT00000001456": 2, "species_10089450": 6, "reaction_10089523": 4, "species_10089520": 5, "species_10089490": 4, "reaction_10089427": 4, "species_10089417": 9, "E1B8Z4": 19, "ENSBTAT00000005749": 2, "species_10089424": 9, "reaction_10089431": 2, "species_10089429": 3, "reaction_10089480": 3, "species_10089476": 6, "species_10089478": 6, "reaction_10089453": 4, "species_10089413": 7, "reaction_10089516": 4, "species_10089513": 6, "reaction_10089455": 3, "species_10050036": 2, "ENSBTAT00000001455": 2, "species_10050038": 3, "F1MJR4": 4, "reaction_10089536": 2, "species_10089534": 2, "reaction_10089538": 3, "species_10089518": 1, "species_10089484": 4, "reaction_10089442": 4, "species_10089435": 4, "species_10089439": 4, "reaction_10089506": 3, "species_10049999": 2, "species_10050001": 3, "reaction_10089540": 3, "species_10089415": 4, "reaction_10089444": 3, "species_10089422": 4, "reaction_10089511": 4, "species_10089508": 4, "reaction_10089446": 3, "species_10050044": 2, "species_10050046": 4, "reaction_10050054": 3, "species_10050032": 2, "species_10050048": 4, "reaction_10089542": 3, "reaction_10061449": 3, "species_10061434": 2, "G3X812": 5, "ENSBTAT00000050083": 3, "species_10061443": 2, "species_10061447": 2, "ENSBTAT00000084118": 1, "reaction_10090834": 3, "species_10090824": 2, "species_10044414": 3, "species_10090832": 3, "reaction_10078393": 5, "species_10078383": 3, "CHEBI:25650": 1, "G3X6L0": 7, "species_10076429": 3, "ENSBTAT00000008936": 4, "species_10038774": 2, "species_10078386": 3, "species_10078390": 2, "ENSBTAT00000010820": 1, "reaction_10052056": 5, "species_379697": 2, "species_159549": 7, "species_10052053": 2, "F1MLG7": 2, "ENSBTAT00000010113": 1, "reaction_10047019": 5, "species_389822": 1, "species_389678": 2, "species_10047016": 4, "E1BC79": 2, "ENSBTAT00000061291": 1, "reaction_10078701": 5, "species_5359017": 1, "species_10078698": 3, "A0A3Q1LMP5": 2, "ENSBTAT00000079667": 1, "A0A3Q1M678": 2, "ENSBTAT00000080669": 1, "reaction_10047022": 6, "species_389819": 1, "reaction_10078366": 5, "species_10078353": 2, "ENSBTAT00000079686": 2, "species_10076427": 5, "species_10078359": 2, "species_10078363": 2, "ENSBTAT00000005171": 1, "reaction_10077458": 5, "species_6784236": 1, "species_6784229": 1, "species_113553": 5, "species_10033725": 4, "P12344": 2, "ENSBTAT00000009440": 1, "reaction_10078402": 7, "species_6793610": 1, "species_2162265": 1, "species_379705": 1, "species_6793613": 1, "species_10078399": 3, "Q5BIP7": 2, "ENSBTAT00000019299": 1, "CHEBI:49883": 2, "reaction_10076441": 5, "species_10076431": 4, "P20821": 3, "CHEBI:14949": 1, "species_10076438": 2, "E1BJQ1": 2, "ENSBTAT00000036700": 1, "reaction_10076459": 6, "species_10076443": 4, "CHEBI:50746": 1, "species_10076456": 3, "F1N206": 2, "ENSBTAT00000033787": 1, "reaction_10076450": 6, "species_200671": 3, "species_5693984": 3, "species_10076447": 2, "ENSBTAT00000002992": 1, "reaction_10051737": 6, "species_10051716": 7, "A0A3Q1LLQ7": 11, "ENSBTAT00000066996": 1, "P07353": 11, "ENSBTAT00000016634": 1, "species_10051722": 6, "species_10043836": 4, "species_10051735": 8, "F1MSN0": 5, "ENSBTAT00000005753": 1, "reaction_10091723": 3, "species_9678984": 1, "species_10051743": 5, "species_10051778": 5, "reaction_10051771": 4, "species_10051760": 7, "species_10051768": 7, "reaction_10051786": 3, "species_10051784": 7, "species_10051756": 7, "species_10051690": 3, "reaction_10051774": 4, "reaction_10051696": 2, "species_10051694": 4, "reaction_10052067": 5, "species_10052064": 4, "A0A3Q1MRR6": 12, "ENSBTAT00000078659": 5, "A0A3Q1MKC7": 7, "ENSBTAT00000073084": 1, "A0A3Q1M066": 3, "ENSBTAT00000071596": 1, "reaction_10051762": 3, "species_10051758": 4, "reaction_10051818": 4, "species_10051814": 6, "A0A3Q1M137": 4, "ENSBTAT00000084456": 4, "A0A3Q1M2W5": 4, "A0A3Q1M4Y4": 4, "A0A3Q1MRS5": 4, "species_10051796": 2, "ENSBTAT00000083334": 2, "species_10051816": 7, "A0A3Q1ML58": 2, "reaction_10055967": 5, "species_10055960": 2, "species_10055964": 2, "ENSBTAT00000074168": 1, "reaction_10051792": 3, "species_10051733": 4, "reaction_10051780": 5, "species_10051702": 2, "species_10051745": 6, "species_10051776": 2, "reaction_10051748": 4, "reaction_10078682": 3, "species_10078678": 2, "ENSBTAT00000043330": 2, "species_10046864": 5, "A0A3Q1M422": 6, "ENSBTAT00000066459": 2, "A0A3Q1MZF8": 6, "ENSBTAT00000074444": 2, "species_10078680": 4, "E1BPK8": 2, "reaction_10078674": 3, "species_10046862": 2, "species_10078670": 2, "ENSBTAT00000064547": 2, "species_10078672": 3, "G3N3T6": 7, "reaction_10046868": 3, "species_10046854": 5, "A0A3Q1MBH3": 3, "ENSBTAT00000073078": 1, "A0A3Q1M5L6": 3, "ENSBTAT00000081984": 1, "A0A3Q1LQ22": 3, "ENSBTAT00000075872": 1, "A0A3Q1M5X2": 3, "ENSBTAT00000069454": 1, "species_10046866": 7, "reaction_10078566": 3, "species_10078562": 7, "F1N5L8": 3, "ENSBTAT00000015639": 1, "F1MJJ9": 3, "ENSBTAT00000054494": 1, "E1B8X9": 3, "ENSBTAT00000013364": 1, "G3N2N1": 3, "ENSBTAT00000072588": 1, "F1MSM8": 3, "ENSBTAT00000005757": 1, "F1N513": 3, "ENSBTAT00000022827": 1, "species_10046858": 2, "species_10078564": 8, "reaction_10034944": 5, "species_73578": 7, "species_73566": 10, "species_10034941": 2, "Q2HJ58": 3, "ENSBTAT00000026261": 1, "reaction_10036903": 7, "species_110644": 1, "species_109386": 8, "species_10034933": 2, "reaction_10076792": 5, "species_5694568": 2, "species_5694580": 1, "species_5694567": 1, "species_10076789": 2, "ENSBTAT00000022154": 1, "reaction_10059002": 5, "species_1500581": 8, "species_1498738": 3, "species_1524021": 22, "species_10058940": 7, "A0A3Q1NMD6": 5, "ENSBTAT00000078451": 1, "A0A3Q1LR65": 6, "ENSBTAT00000067227": 1, "A0A3Q1LYR5": 5, "ENSBTAT00000078489": 1, "F1MG30": 9, "ENSBTAT00000003576": 1, "F1MNU5": 7, "ENSBTAT00000006775": 1, "reaction_10059853": 5, "species_1602372": 1, "species_1602366": 9, "species_10059844": 14, "F1MSG5": 2, "ENSBTAT00000005791": 1, "E1BGU4": 2, "ENSBTAT00000028684": 1, "Q56JZ2": 6, "ENSBTAT00000007570": 1, "A0A3Q1MFE1": 3, "ENSBTAT00000078105": 1, "A5D7L0": 2, "ENSBTAT00000020263": 1, "A0A3Q1MNU5": 2, "ENSBTAT00000080344": 1, "A0A3Q1M5P6": 2, "ENSBTAT00000077544": 1, "reaction_10059004": 5, "species_10058967": 5, "E1BE78": 2, "ENSBTAT00000017658": 1, "reaction_10084526": 5, "species_426925": 10, "species_6814253": 2, "species_10084523": 2, "reaction_10058899": 5, "species_10058882": 4, "G8JL05": 3, "ENSBTAT00000054491": 2, "F1MH02": 3, "ENSBTAT00000010729": 1, "reaction_10058885": 5, "species_1498729": 2, "reaction_10058980": 5, "species_10058977": 4, "reaction_10046888": 4, "species_10046882": 3, "A0A3Q1M2W6": 3, "ENSBTAT00000083184": 1, "C5NU11": 3, "ENSBTAT00000008067": 1, "species_10046872": 3, "ENSBTAT00000079165": 2, "species_10046884": 4, "A0A3Q1MQR6": 3, "species_10046886": 3, "reaction_10091743": 3, "species_9679406": 1, "reaction_10064439": 3, "species_2161525": 1, "species_2161185": 2, "species_10051266": 4, "A7MBE0": 2, "ENSBTAT00000004059": 1, "reaction_10064584": 6, "species_2162081": 1, "species_10034181": 3, "F1MZP8": 4, "ENSBTAT00000009185": 1, "reaction_10075063": 3, "species_10050549": 2, "species_10075061": 4, "reaction_10086241": 3, "species_10084943": 8, "ENSBTAT00000070567": 7, "species_10086237": 7, "A0A3Q1MF28": 5, "ENSBTAT00000078064": 1, "Q1JQE0": 6, "ENSBTAT00000010697": 2, "Q3SZ41": 5, "ENSBTAT00000004696": 2, "E1B8D6": 28, "ENSBTAT00000021556": 2, "A0A3Q1MLT2": 17, "ENSBTAT00000075969": 1, "F1MD32": 12, "ENSBTAT00000005092": 2, "species_10086239": 8, "A0A3Q1MYL2": 13, "reaction_10072913": 3, "species_10072911": 13, "F1MYF9": 25, "ENSBTAT00000023383": 5, "species_10043237": 7, "species_10065265": 14, "reaction_10072944": 4, "species_10072941": 14, "reaction_10072946": 4, "species_10061098": 5, "reaction_10073152": 4, "species_10073138": 13, "species_10073149": 13, "reaction_10073140": 3, "reaction_10073156": 3, "species_10073154": 15, "reaction_10073159": 5, "reaction_10073234": 5, "species_10065273": 15, "reaction_10073145": 4, "species_10073142": 14, "species_10065269": 15, "reaction_10073019": 5, "species_10073016": 15, "reaction_10073147": 3, "species_10065267": 14, "reaction_10073021": 3, "reaction_10087376": 5, "reaction_10073011": 5, "species_10073006": 13, "species_10073009": 12, "reaction_10073014": 3, "species_10072959": 6, "reaction_10062984": 5, "species_10062948": 9, "F1MZX8": 19, "ENSBTAT00000011475": 1, "F1MER7": 21, "A0A3Q1N5R3": 21, "ENSBTAT00000082452": 1, "A0A3Q1LTY7": 19, "ENSBTAT00000085269": 1, "A0A3Q1LZ29": 23, "ENSBTAT00000082766": 1, "E1BKS1": 21, "ENSBTAT00000020125": 1, "species_10062971": 8, "species_10062981": 3, "A8E4L2": 2, "ENSBTAT00000080227": 1, "reaction_10063610": 5, "species_10063045": 8, "species_10063068": 10, "species_10063607": 2, "ENSBTAT00000086518": 1, "reaction_10063633": 5, "species_10063091": 9, "species_10063630": 6, "Q0VD21": 2, "ENSBTAT00000085321": 1, "E1B729": 2, "ENSBTAT00000025630": 1, "E1BKQ1": 2, "ENSBTAT00000023123": 1, "E1BNJ7": 2, "ENSBTAT00000044024": 1, "E1BP03": 2, "ENSBTAT00000010350": 1, "reaction_10063216": 2, "species_10063132": 8, "species_10063214": 8, "reaction_10063603": 5, "species_10063114": 8, "species_10063130": 8, "species_10063600": 3, "A0A3Q1LS54": 2, "ENSBTAT00000078465": 1, "A0A3Q1LTK3": 2, "ENSBTAT00000075020": 1, "reaction_10063010": 5, "species_2022884": 4, "species_10063007": 8, "reaction_10063586": 5, "species_10063583": 2, "Q0VCB5": 2, "ENSBTAT00000009799": 1, "reaction_10051589": 5, "species_744229": 3, "species_735698": 1, "species_744234": 3, "species_10051584": 3, "ENSBTAT00000026562": 2, "reaction_10084090": 3, "species_10084086": 4, "species_10084084": 2, "ENSBTAT00000011655": 3, "species_10084088": 4, "F6Q0F9": 2, "reaction_10084096": 5, "species_10084093": 2, "reaction_10076112": 4, "species_10076107": 4, "A0A3Q1MUE2": 3, "ENSBTAT00000080652": 1, "species_10036828": 20, "species_10076109": 4, "reaction_10076119": 3, "species_10039539": 11, "species_10039537": 5, "species_10076116": 2, "ENSBTAT00000046166": 2, "reaction_10089947": 3, "species_10089943": 6, "A0A3Q1LHF1": 8, "ENSBTAT00000075877": 2, "A0A3Q1LSX9": 5, "ENSBTAT00000073284": 1, "A0A3Q1LM61": 5, "ENSBTAT00000075730": 1, "A0A3Q1LV55": 9, "ENSBTAT00000079495": 1, "species_10073483": 8, "Q1RMJ6": 14, "ENSBTAT00000018998": 1, "species_10089945": 8, "reaction_10092364": 2, "species_10092362": 3, "reaction_10089937": 5, "species_10089932": 4, "species_10089934": 12, "A0A3Q1LUW4": 4, "ENSBTAT00000069851": 1, "A0A3Q1N6F4": 5, "ENSBTAT00000072165": 1, "A0A3Q1MQP9": 16, "ENSBTAT00000086853": 3, "A0A3Q1MRV3": 7, "ENSBTAT00000083879": 2, "A0A3Q1LFQ5": 5, "ENSBTAT00000066417": 2, "A0A3Q1MN47": 5, "ENSBTAT00000081099": 2, "A0A3Q1LKT3": 4, "ENSBTAT00000074225": 2, "A0A3Q1LNE2": 4, "ENSBTAT00000077218": 1, "A0A3Q1LQ45": 3, "ENSBTAT00000078928": 1, "F1N2G5": 4, "ENSBTAT00000002373": 1, "F1MB21": 2, "ENSBTAT00000017829": 1, "reaction_10089952": 5, "species_10089949": 4, "E1BM23": 7, "ENSBTAT00000038690": 1, "reaction_10092392": 3, "species_10092388": 4, "A5PK69": 6, "ENSBTAT00000079280": 1, "species_10092384": 1, "species_10092390": 3, "reaction_10090330": 5, "species_10090323": 5, "species_10090325": 5, "species_10090327": 4, "F1MLS2": 8, "ENSBTAT00000061086": 1, "reaction_10092394": 2, "reaction_10090349": 3, "species_10090341": 1, "species_10090347": 3, "reaction_10090339": 5, "species_10090336": 6, "F1N6V1": 3, "ENSBTAT00000003400": 1, "A4IF90": 2, "ENSBTAT00000061453": 1, "reaction_10089930": 3, "species_10089926": 10, "A0A3Q1MFP5": 10, "ENSBTAT00000068010": 1, "A0A3Q1LJH7": 4, "ENSBTAT00000073587": 2, "G3X696": 3, "ENSBTAT00000001346": 1, "F1MBT6": 3, "ENSBTAT00000046371": 1, "species_10089928": 12, "reaction_10089149": 5, "species_10089146": 14, "Q08DB1": 2, "ENSBTAT00000039899": 1, "F1MGB9": 2, "ENSBTAT00000052139": 1, "A0A3Q1M2Q1": 2, "ENSBTAT00000076617": 1, "E1BI70": 6, "ENSBTAT00000027682": 1, "F1MYQ4": 2, "ENSBTAT00000011665": 1, "G3MXE8": 2, "ENSBTAT00000066138": 1, "E1BIM3": 2, "ENSBTAT00000035838": 1, "A4FV18": 2, "ENSBTAT00000020147": 1, "A0A3Q1LGT5": 2, "ENSBTAT00000075956": 1, "reaction_10089888": 3, "species_10089862": 4, "species_10089884": 2, "species_10089886": 4, "reaction_10089011": 5, "species_10089008": 20, "E1BH51": 2, "ENSBTAT00000005514": 1, "E1BQ24": 3, "ENSBTAT00000007450": 1, "A0A3Q1M8D9": 3, "ENSBTAT00000071999": 1, "E1BDY4": 2, "ENSBTAT00000082024": 1, "A0A3Q1LJS1": 3, "ENSBTAT00000068893": 1, "A0A3Q1N5A2": 3, "ENSBTAT00000067575": 1, "A0A3Q1MA88": 3, "ENSBTAT00000069507": 1, "A0A3Q1MD11": 4, "ENSBTAT00000081804": 1, "reaction_10089890": 2, "reaction_10089860": 3, "species_10089854": 3, "ENSBTAT00000007933": 2, "species_10089858": 4, "A0A452DIS6": 3, "reaction_10090125": 3, "species_10090093": 5, "Q1RMI2": 14, "ENSBTAT00000000453": 1, "species_10090123": 4, "reaction_10090145": 3, "species_10090117": 4, "species_10090141": 2, "species_10090143": 4, "reaction_10090115": 3, "species_10090111": 7, "A0A3Q1LX25": 3, "ENSBTAT00000069555": 1, "A0A3Q1LWX5": 6, "ENSBTAT00000081739": 1, "A0A3Q1MT94": 3, "ENSBTAT00000085032": 1, "F1MTR1": 5, "ENSBTAT00000001190": 1, "A0A3Q1NNR4": 3, "ENSBTAT00000083570": 1, "species_10037305": 6, "species_10090113": 9, "reaction_10090098": 5, "species_10090095": 3, "reaction_10090103": 5, "species_10090100": 2, "reaction_10090119": 2, "reaction_10090089": 2, "species_10037299": 8, "Q9TU25": 10, "ENSBTAT00000014666": 1, "species_10073712": 5, "reaction_10090091": 3, "species_10073714": 10, "reaction_10090077": 3, "species_10090073": 4, "A0A3Q1MFB9": 5, "ENSBTAT00000080368": 1, "species_10090075": 6, "reaction_10092380": 3, "species_10092374": 4, "species_10092376": 1, "species_10092378": 3, "reaction_10092382": 2, "reaction_10090082": 5, "species_10090033": 4, "species_10090079": 4, "reaction_10092370": 2, "species_10092368": 3, "reaction_10090087": 5, "species_10090084": 7, "A0A3Q1M4M7": 2, "ENSBTAT00000071096": 1, "A0A3Q1MKN5": 2, "ENSBTAT00000080659": 1, "reaction_10090203": 5, "species_10090193": 4, "A4FV20": 3, "ENSBTAT00000022858": 1, "species_10090191": 4, "species_10090200": 2, "E1BNA6": 2, "ENSBTAT00000002840": 1, "reaction_10090198": 5, "species_10090195": 4, "reaction_10091994": 3, "species_10091990": 7, "E1BLB2": 5, "ENSBTAT00000010671": 1, "A0A3Q1LPM3": 3, "ENSBTAT00000068488": 1, "F1N4C5": 3, "ENSBTAT00000002375": 1, "A0A3Q1M6F8": 5, "ENSBTAT00000077393": 1, "species_10091948": 4, "F1MUP6": 3, "ENSBTAT00000009719": 2, "species_10091992": 9, "reaction_10092022": 3, "species_10091946": 2, "reaction_10091832": 4, "species_10091827": 4, "Q3SZA1": 6, "ENSBTAT00000046161": 1, "species_10091829": 5, "reaction_10091864": 3, "species_10091860": 5, "A0A452DIN5": 3, "ENSBTAT00000020331": 1, "F1MXR0": 3, "ENSBTAT00000030984": 1, "F1MFC6": 3, "ENSBTAT00000072393": 1, "species_10091862": 7, "reaction_10091921": 5, "species_10091918": 2, "reaction_10090266": 3, "species_10090262": 6, "A0A3Q1MPX4": 3, "ENSBTAT00000082212": 1, "F1MS60": 3, "ENSBTAT00000012813": 1, "Q2KI46": 3, "ENSBTAT00000032505": 1, "A2VDU0": 3, "ENSBTAT00000018391": 1, "species_10090239": 5, "F1MK42": 5, "ENSBTAT00000018269": 1, "species_10090264": 8, "reaction_10090369": 2, "species_10090367": 3, "reaction_10090246": 5, "species_10090241": 3, "species_10090243": 3, "reaction_10092002": 3, "species_10091998": 2, "ENSBTAT00000045869": 2, "species_10092000": 4, "A5PKJ7": 3, "reaction_10092020": 3, "species_10092016": 4, "species_10092018": 6, "reaction_10063353": 5, "species_10047757": 3, "ENSBTAT00000061497": 2, "species_10047760": 3, "species_10047644": 2, "reaction_10073755": 6, "species_352327": 9, "species_3299686": 2, "species_10073752": 6, "E1BFF3": 2, "ENSBTAT00000018021": 1, "reaction_10091180": 5, "species_10091177": 4, "species_10091162": 5, "species_10040565": 3, "reaction_10091169": 3, "species_10091164": 2, "ENSBTAT00000022592": 3, "species_10091166": 6, "Q5BIN5": 7, "reaction_10073731": 8, "species_10073729": 10, "P28782": 4, "ENSBTAT00000066555": 1, "species_1629751": 1, "reaction_10073716": 3, "reaction_10091175": 5, "species_10091173": 5, "species_10070605": 5, "A0A3Q1MSP9": 9, "ENSBTAT00000070692": 1, "reaction_10063374": 3, "species_10043441": 4, "species_10063372": 10, "A0A3Q1M5Y2": 7, "ENSBTAT00000084883": 1, "Q148J6": 3, "ENSBTAT00000070990": 1, "Q3MHR7": 3, "ENSBTAT00000070600": 1, "G3MXC8": 7, "ENSBTAT00000064442": 1, "A0A3Q1NMB5": 3, "ENSBTAT00000082840": 1, "Q58CQ2": 3, "ENSBTAT00000064158": 1, "species_10061166": 9, "reaction_10073577": 3, "species_10073573": 2, "species_10073575": 4, "reaction_10072515": 3, "species_10072511": 2, "species_10072505": 4, "species_10072513": 6, "reaction_10073842": 3, "species_10055513": 5, "Q08DH4": 6, "ENSBTAT00000025752": 1, "A6H7H2": 6, "ENSBTAT00000023001": 1, "A0A3Q1MWH8": 6, "ENSBTAT00000071358": 1, "species_10073840": 8, "reaction_10073806": 3, "species_10073802": 5, "species_10050472": 2, "species_10073804": 6, "reaction_10073796": 4, "species_10073792": 2, "ENSBTAT00000076885": 2, "species_10073788": 2, "ENSBTAT00000029161": 2, "species_10073784": 5, "species_10073794": 7, "G5E5S3": 2, "Q2T9P1": 2, "reaction_10073561": 3, "species_10073541": 4, "ENSBTAT00000070929": 3, "species_10043459": 5, "species_10073543": 5, "A0A3Q1LLJ2": 4, "reaction_10073503": 3, "species_10073499": 2, "E1B718": 4, "ENSBTAT00000022075": 1, "species_10073501": 5, "reaction_10073525": 3, "species_10073521": 2, "ENSBTAT00000068363": 2, "species_10073517": 5, "A0A3Q1M6W5": 3, "ENSBTAT00000078036": 1, "species_10073523": 6, "A0A3Q1LMM5": 2, "reaction_10073493": 3, "species_10073489": 2, "species_10073491": 4, "reaction_10073557": 3, "species_10068967": 3, "species_10073553": 2, "ENSBTAT00000016981": 2, "species_10073555": 4, "E1BJP4": 3, "reaction_10073559": 2, "reaction_10073547": 5, "species_10073539": 2, "A0A3Q1MSR1": 5, "ENSBTAT00000069763": 1, "species_10073545": 7, "reaction_10068939": 3, "species_10068935": 4, "species_10068931": 5, "species_10068937": 6, "reaction_10073549": 3, "species_10073535": 2, "reaction_10073569": 3, "species_10073565": 2, "ENSBTAT00000072829": 2, "species_10073567": 4, "A0A3Q1M5I0": 2, "reaction_10073507": 3, "species_10073505": 6, "reaction_10043461": 3, "species_10043457": 2, "reaction_10068933": 3, "species_10068929": 2, "species_10068927": 2, "reaction_10092203": 3, "species_10092199": 7, "Q08DW1": 6, "ENSBTAT00000014511": 1, "Q3SX32": 5, "ENSBTAT00000015669": 2, "Q0VCB4": 5, "ENSBTAT00000026403": 1, "G3N2Y1": 9, "ENSBTAT00000064452": 1, "E1BL53": 12, "ENSBTAT00000030804": 1, "species_10083329": 6, "A0A3Q1M2K6": 5, "ENSBTAT00000080085": 2, "species_10092201": 9, "reaction_10092205": 3, "species_10083327": 2, "reaction_10092208": 4, "species_10083335": 4, "reaction_10071262": 3, "species_10044442": 4, "species_10071258": 2, "ENSBTAT00000011740": 2, "species_10071260": 3, "A7MB71": 2, "reaction_10064933": 1, "species_10064931": 6, "F1N727": 2, "ENSBTAT00000060953": 1, "E1BJ37": 2, "ENSBTAT00000005438": 1, "reaction_10043311": 3, "species_10042988": 3, "A0A3Q1LSA1": 3, "ENSBTAT00000078787": 1, "F1MCE7": 3, "ENSBTAT00000000282": 1, "species_10043000": 3, "A0A3Q1MGJ6": 5, "ENSBTAT00000077971": 2, "A0A3Q1LP90": 3, "ENSBTAT00000073964": 1, "species_10043002": 5, "reaction_10084542": 3, "species_10084532": 2, "F1MZL1": 3, "ENSBTAT00000019912": 1, "species_10084538": 2, "E1BHR7": 3, "ENSBTAT00000024657": 1, "species_10084540": 3, "reaction_10042976": 2, "species_10042969": 2, "ENSBTAT00000072746": 1, "reaction_10056354": 4, "species_10056341": 5, "P07995": 6, "ENSBTAT00000066382": 1, "F1MSQ2": 3, "ENSBTAT00000046665": 2, "species_10056351": 4, "reaction_10056356": 4, "species_10056339": 2, "species_10042992": 2, "species_10045724": 2, "reaction_10068704": 3, "species_10060420": 2, "ENSBTAT00000080996": 2, "species_10043116": 4, "species_10068702": 6, "F1N7M1": 5, "reaction_10068707": 5, "species_392417": 7, "reaction_10067694": 3, "species_10067672": 6, "A0A3Q1LJY1": 7, "ENSBTAT00000079758": 1, "A0A3Q1LTE2": 7, "ENSBTAT00000069289": 1, "A0A3Q1M3K5": 7, "ENSBTAT00000073140": 1, "G3MWG5": 7, "ENSBTAT00000067597": 3, "species_10067691": 6, "reaction_10067696": 3, "species_10067670": 3, "species_10067668": 6, "reaction_10067698": 3, "species_10067689": 4, "reaction_10068095": 5, "species_10068083": 6, "A0A3Q1M230": 6, "ENSBTAT00000085809": 1, "E1B8R5": 6, "ENSBTAT00000001917": 1, "Q3T139": 3, "ENSBTAT00000038099": 2, "species_10068071": 7, "species_10068092": 2, "ENSBTAT00000078346": 1, "reaction_10068073": 3, "species_10068054": 2, "species_10068069": 5, "reaction_10068088": 3, "species_10041524": 3, "species_10068067": 3, "species_10068075": 5, "reaction_10068078": 4, "species_197277": 4, "reaction_10068086": 3, "reaction_10067879": 5, "species_77087": 37, "species_10067848": 3, "P62803": 77, "ENSBTAT00000072717": 1, "A0A3Q1LMV7": 77, "ENSBTAT00000085055": 1, "species_77502": 37, "species_10067852": 3, "species_10067876": 9, "F1MHP8": 2, "ENSBTAT00000012057": 1, "E1BEP4": 13, "ENSBTAT00000001294": 1, "A0A3Q1MZ99": 4, "ENSBTAT00000068676": 1, "A0A3Q1MAN6": 6, "ENSBTAT00000079320": 1, "A4FUE3": 15, "ENSBTAT00000021204": 1, "E1BPF3": 2, "ENSBTAT00000080372": 1, "A0A3Q1M6V2": 2, "ENSBTAT00000067448": 1, "A0A3Q1N7T9": 13, "ENSBTAT00000083957": 1, "reaction_10071330": 3, "species_10071326": 4, "F1N5R1": 10, "ENSBTAT00000021312": 1, "species_10071324": 2, "ENSBTAT00000071795": 2, "species_10071328": 5, "A0A3Q1N0Q2": 2, "reaction_10069645": 3, "species_10069631": 7, "F1MH47": 5, "ENSBTAT00000029170": 1, "F1ME23": 5, "ENSBTAT00000078037": 1, "F6RLD1": 5, "ENSBTAT00000018083": 1, "A0A452DIK6": 5, "ENSBTAT00000017631": 1, "F1MLJ7": 14, "ENSBTAT00000061059": 2, "species_10069641": 3, "A0A3Q1MCX1": 4, "ENSBTAT00000083590": 1, "E1BNT4": 4, "ENSBTAT00000026797": 1, "species_10069643": 9, "reaction_10069647": 3, "species_10069615": 3, "species_10069629": 4, "reaction_10069664": 3, "species_10069661": 8, "reaction_10069607": 3, "species_10069603": 2, "ENSBTAT00000025871": 2, "species_10043149": 4, "species_10069605": 3, "F1MP88": 2, "reaction_10068923": 3, "species_10068919": 2, "species_10068917": 5, "F1N4K7": 3, "ENSBTAT00000002946": 1, "F1N4C0": 4, "ENSBTAT00000014355": 1, "species_10068921": 6, "reaction_10069896": 3, "species_10069892": 4, "E1BC57": 3, "ENSBTAT00000061589": 1, "species_10069894": 5, "reaction_10069882": 3, "species_10069874": 4, "F1MLJ8": 5, "ENSBTAT00000061370": 2, "species_10069878": 4, "reaction_10069876": 3, "species_10069862": 2, "reaction_10069299": 3, "species_10043451": 3, "P02584": 3, "ENSBTAT00000024367": 2, "E1BHJ0": 3, "species_10069297": 5, "reaction_10069448": 5, "species_10069445": 5, "species_10069441": 2, "species_10037002": 7, "reaction_10069456": 3, "species_10069452": 2, "species_10069454": 5, "reaction_10069459": 4, "reaction_10067128": 3, "species_10067122": 10, "A0A3Q1LVG1": 8, "ENSBTAT00000068978": 1, "F1MN70": 8, "ENSBTAT00000018592": 1, "F1N6L8": 8, "ENSBTAT00000002188": 1, "A0A3Q1MQ82": 8, "ENSBTAT00000083229": 1, "A0A3Q1MJR6": 8, "ENSBTAT00000085976": 1, "species_10066990": 2, "ENSBTAT00000077814": 4, "species_10067126": 11, "A0A3Q1MGH5": 7, "reaction_10067200": 3, "species_10067168": 12, "species_10067198": 18, "A0A3Q1M1A0": 2, "ENSBTAT00000086580": 1, "A6H6X8": 2, "ENSBTAT00000018985": 1, "A0A3Q1MPF5": 2, "ENSBTAT00000081055": 1, "A4D7S0": 2, "ENSBTAT00000010650": 1, "F1MEW8": 2, "ENSBTAT00000012148": 1, "F1MK64": 2, "ENSBTAT00000020402": 1, "species_10067130": 3, "reaction_10067202": 2, "reaction_10066994": 2, "species_10066988": 5, "Q1RMH8": 3, "ENSBTAT00000025026": 1, "Q0VD53": 3, "ENSBTAT00000022455": 1, "Q2HJG5": 3, "ENSBTAT00000003239": 1, "species_10066992": 5, "reaction_10068837": 2, "species_10068795": 11, "species_10068835": 10, "reaction_10067124": 2, "species_10067086": 9, "reaction_10067204": 2, "species_10066982": 2, "reaction_10068839": 2, "reaction_10041640": 5, "species_10041614": 10, "A0A3Q1LMC7": 11, "ENSBTAT00000086393": 2, "E1BEW4": 12, "ENSBTAT00000057200": 1, "P35507": 12, "ENSBTAT00000030064": 1, "A0A3Q1MI36": 12, "ENSBTAT00000064284": 1, "A0A3Q1NFM1": 12, "ENSBTAT00000052805": 1, "E1BL05": 11, "ENSBTAT00000011639": 2, "species_10041594": 10, "reaction_10041629": 5, "species_10041610": 10, "reaction_10041647": 4, "species_10041644": 9, "species_10041634": 10, "reaction_10041637": 5, "reaction_10063849": 3, "species_10063841": 13, "Q3ZCF3": 28, "ENSBTAT00000035306": 2, "A0A3Q1LNF8": 37, "ENSBTAT00000075328": 2, "F1MYD0": 29, "ENSBTAT00000068449": 2, "species_10063845": 15, "reaction_10087597": 3, "species_10087593": 3, "species_10087595": 6, "reaction_10071356": 3, "species_10071346": 2, "species_10071352": 2, "A0A3Q1M504": 3, "ENSBTAT00000066753": 1, "species_10071354": 3, "reaction_10069651": 2, "species_10069649": 4, "reaction_10041583": 7, "species_10041570": 2, "species_10041520": 5, "species_10041566": 7, "species_10041579": 2, "species_10041581": 10, "reaction_10070931": 4, "species_10041590": 9, "reaction_10063843": 3, "species_10043873": 7, "species_10041599": 12, "reaction_10041604": 4, "reaction_10041606": 2, "reaction_10060556": 5, "species_10060426": 5, "A0A3Q1MBL1": 3, "ENSBTAT00000076329": 2, "A6QLC5": 4, "ENSBTAT00000008015": 1, "reaction_10060448": 5, "species_1806240": 4, "species_10060445": 3, "F1MHR4": 6, "ENSBTAT00000024007": 1, "F1MHT2": 6, "ENSBTAT00000008517": 1, "reaction_10087531": 3, "species_10087525": 2, "A0A3Q1MWB8": 4, "ENSBTAT00000079180": 1, "species_10087523": 1, "species_10087529": 2, "reaction_10065099": 3, "species_10043178": 4, "species_10065097": 3, "species_6810412": 18, "reaction_10065227": 3, "reaction_10036981": 4, "species_10036972": 4, "A0A3Q1M5T5": 3, "ENSBTAT00000086155": 1, "species_10036978": 4, "reaction_10049478": 4, "species_10049470": 4, "E1BIP3": 5, "ENSBTAT00000009431": 1, "species_10049475": 4, "reaction_10037022": 4, "species_10037019": 5, "A0A3Q1MCV4": 2, "ENSBTAT00000066843": 1, "P14100": 4, "ENSBTAT00000052318": 1, "reaction_10037024": 3, "reaction_10037004": 5, "species_10036997": 9, "A0A3Q1MA58": 9, "ENSBTAT00000080069": 1, "E1B9K3": 9, "ENSBTAT00000069484": 1, "E1BM79": 9, "ENSBTAT00000073752": 1, "reaction_10041863": 5, "species_10041855": 2, "species_10041860": 2, "species_112275": 23, "reaction_10063544": 2, "species_10063538": 4, "F1MK73": 12, "ENSBTAT00000006112": 6, "A0A3Q1MEH9": 4, "ENSBTAT00000069935": 2, "species_10063542": 3, "reaction_10063550": 3, "species_10063333": 7, "ENSBTAT00000084991": 4, "species_10063546": 2, "ENSBTAT00000038824": 2, "species_10063548": 3, "F1N2D3": 5, "A0A3Q1NBB6": 6, "reaction_10063408": 3, "species_10063404": 2, "ENSBTAT00000019472": 2, "species_10063259": 4, "E1B9F9": 5, "ENSBTAT00000019161": 1, "E1BCH5": 5, "ENSBTAT00000020062": 1, "species_10063406": 4, "F1N3I6": 2, "reaction_10063568": 3, "species_10063336": 4, "species_10063566": 3, "reaction_10063346": 3, "species_10063303": 6, "A0A3Q1M4X1": 4, "ENSBTAT00000077481": 1, "A0A452DIV8": 4, "ENSBTAT00000025212": 1, "species_10063344": 4, "reaction_10063317": 5, "species_10057276": 7, "species_10063312": 2, "species_10063314": 5, "A0A3Q1M4W1": 5, "ENSBTAT00000081411": 1, "A0A3Q1MBK1": 5, "ENSBTAT00000081480": 1, "reaction_10063380": 2, "species_10063378": 3, "reaction_10063319": 3, "species_10063273": 3, "species_10063275": 5, "reaction_10063382": 2, "species_10057280": 5, "reaction_10063305": 6, "species_10063290": 3, "species_10063292": 5, "reaction_10063338": 6, "reaction_10063342": 3, "species_10063340": 4, "reaction_10063534": 5, "reaction_10063329": 3, "species_10037668": 6, "A0A140T894": 39, "ENSBTAT00000022411": 2, "species_10063327": 3, "reaction_10063554": 3, "species_10063536": 3, "species_10063552": 3, "reaction_10063556": 3, "reaction_10043753": 7, "species_10037714": 2, "ENSBTAT00000078264": 5, "species_10037676": 3, "ENSBTAT00000016610": 5, "species_10043750": 2, "species_10043747": 2, "reaction_10041333": 2, "species_10039497": 3, "reaction_10043739": 2, "species_10043729": 7, "A0A3Q1M6A8": 9, "ENSBTAT00000083119": 2, "species_10043737": 6, "reaction_10043744": 3, "species_10043741": 6, "species_10043723": 2, "reaction_10043778": 4, "species_10043719": 4, "species_10043727": 2, "species_10043761": 2, "reaction_10043877": 3, "species_10043875": 5, "Q8WNW7": 4, "reaction_10041470": 3, "species_10041467": 2, "reaction_10071524": 3, "species_10071516": 8, "Q3SYW8": 15, "ENSBTAT00000034719": 1, "A0A3Q1MT71": 15, "ENSBTAT00000070103": 1, "Q3SZK6": 33, "ENSBTAT00000008367": 2, "Q2KI74": 17, "ENSBTAT00000016776": 1, "E1B9D9": 25, "ENSBTAT00000013869": 1, "species_10071521": 8, "reaction_10071556": 3, "species_10071552": 4, "E1BMK3": 3, "ENSBTAT00000061147": 1, "Q1JPC8": 7, "ENSBTAT00000022612": 1, "E1BDF2": 3, "ENSBTAT00000049670": 1, "species_10071554": 9, "reaction_10071526": 3, "species_10036142": 4, "species_10071514": 5, "reaction_10037964": 4, "species_10035378": 3, "ENSBTAT00000024322": 2, "species_10036144": 4, "species_10037952": 7, "Q645M6": 19, "species_10037962": 3, "A0A3Q1NKI9": 9, "ENSBTAT00000069028": 2, "reaction_10067908": 4, "species_10036154": 2, "A0A452DJ61": 4, "ENSBTAT00000035815": 3, "species_10067885": 2, "species_10067899": 3, "species_10067905": 3, "E1B867": 2, "ENSBTAT00000001519": 1, "reaction_10092026": 3, "species_10067893": 8, "A0A3Q1MLX3": 9, "ENSBTAT00000085853": 5, "species_10092024": 8, "species_10068040": 3, "reaction_10092031": 3, "species_10092028": 7, "species_10071528": 3, "reaction_10071534": 4, "species_10071532": 5, "reaction_10084723": 4, "species_10084710": 2, "species_10084708": 2, "species_10084720": 3, "A0A3Q1MBP7": 2, "ENSBTAT00000077127": 1, "E1BKF8": 2, "ENSBTAT00000035792": 1, "reaction_10071541": 5, "species_10071539": 2, "ENSBTAT00000026221": 1, "reaction_10067895": 4, "species_10067887": 4, "species_10035384": 6, "reaction_10035726": 3, "species_10033920": 2, "ENSBTAT00000014282": 2, "species_10033916": 2, "ENSBTAT00000046575": 2, "species_10033922": 4, "A6H6Z6": 11, "A5D7R0": 11, "reaction_10036146": 3, "species_10035380": 5, "species_10035386": 7, "reaction_10036148": 3, "species_10033924": 4, "reaction_10033926": 2, "reaction_10045016": 5, "species_10045007": 6, "P61223": 7, "ENSBTAT00000019575": 1, "P62833": 16, "ENSBTAT00000068678": 1, "species_10045005": 6, "species_10045013": 4, "species_6797635": 8, "E1BG59": 4, "ENSBTAT00000029159": 1, "reaction_10053213": 5, "species_10047532": 4, "E1BPX7": 4, "ENSBTAT00000061074": 2, "A0A3Q1LHN3": 4, "ENSBTAT00000085533": 2, "reaction_10049279": 3, "species_10037443": 3, "species_10049276": 3, "reaction_10049506": 2, "species_10049502": 10, "species_10049504": 10, "reaction_10071673": 6, "species_975599": 4, "species_975622": 9, "species_10071670": 4, "F1MFZ4": 3, "ENSBTAT00000003769": 1, "reaction_10076840": 7, "species_5362565": 1, "species_5362520": 4, "species_10076837": 2, "ENSBTAT00000010485": 1, "reaction_10071691": 6, "species_10071688": 4, "F1MZD5": 2, "ENSBTAT00000023493": 1, "E1BM93": 4, "ENSBTAT00000002535": 2, "Q17QW3": 2, "ENSBTAT00000006933": 1, "reaction_10071659": 7, "species_5334816": 3, "species_10071656": 3, "P48644": 3, "ENSBTAT00000010661": 1, "F1MHR3": 2, "ENSBTAT00000012030": 1, "reaction_10072397": 3, "species_10071664": 3, "ENSBTAT00000017158": 2, "species_10071666": 4, "species_215573": 9, "P62964": 2, "reaction_10071678": 6, "species_30927": 2, "species_32737": 7, "species_10071675": 3, "Q27979": 3, "ENSBTAT00000065932": 1, "reaction_10072433": 6, "species_5623644": 1, "species_5623648": 1, "species_163953": 7, "species_5623650": 1, "species_5623649": 1, "species_10072430": 2, "ENSBTAT00000029403": 1, "reaction_10072225": 6, "reaction_10071648": 6, "species_10071645": 4, "Q8HYR6": 2, "ENSBTAT00000005986": 1, "Q0V8D0": 2, "ENSBTAT00000001829": 1, "Q8HZT6": 3, "ENSBTAT00000026830": 1, "reaction_10044211": 8, "species_5362524": 1, "species_10044208": 2, "ENSBTAT00000056396": 2, "reaction_10071668": 9, "species_5362521": 1, "species_10044290": 5, "F1MZS4": 2, "ENSBTAT00000028140": 1, "E1BHJ4": 2, "ENSBTAT00000016198": 1, "E1BDT5": 2, "reaction_10071407": 3, "species_10071399": 3, "G3X6X1": 6, "ENSBTAT00000015305": 1, "A6H7I6": 15, "ENSBTAT00000000860": 1, "species_10071403": 4, "A0A3Q1LX32": 4, "ENSBTAT00000087158": 3, "species_10071405": 6, "reaction_10071397": 3, "species_10071393": 2, "species_10071395": 4, "reaction_10072628": 3, "species_10072626": 4, "species_10071401": 2, "reaction_10072630": 2, "reaction_10090456": 3, "species_10090450": 14, "Q5E9B6": 12, "ENSBTAT00000071739": 2, "F1MPA7": 5, "ENSBTAT00000013888": 1, "B7TCI5": 9, "ENSBTAT00000084466": 1, "A0A3Q1MSZ9": 9, "ENSBTAT00000087441": 1, "F1N0W0": 9, "ENSBTAT00000023086": 1, "F1MGM4": 12, "ENSBTAT00000061343": 1, "A0A3Q1MY21": 12, "ENSBTAT00000086068": 1, "species_192060": 10, "CHEBI:67237": 8, "species_9024328": 10, "CHEBI:41633": 8, "species_10090454": 8, "species_10090444": 7, "reaction_10090559": 3, "species_10047785": 3, "ENSBTAT00000064008": 3, "species_10090557": 9, "G3N0C2": 7, "reaction_10090563": 3, "species_10053052": 10, "species_10090561": 9, "reaction_10090452": 3, "species_10090448": 9, "species_9024383": 6, "reaction_10090555": 3, "species_10090551": 5, "species_10090553": 10, "reaction_10090571": 3, "species_10090565": 8, "species_10090569": 8, "reaction_10090567": 3, "species_10044694": 5, "reaction_10090712": 3, "species_10045570": 2, "ENSBTAT00000005899": 2, "species_10090710": 3, "Q9XSB5": 8, "reaction_10092314": 3, "species_10086682": 5, "P26882": 3, "ENSBTAT00000022180": 1, "species_1254400": 6, "species_10086684": 6, "reaction_10089761": 3, "species_10089757": 9, "Q2HJ27": 6, "ENSBTAT00000076263": 2, "F2Z4J1": 3, "ENSBTAT00000056983": 1, "Q5E9F8": 38, "ENSBTAT00000034695": 2, "species_10089759": 10, "reaction_10091115": 5, "species_10091106": 2, "species_10091108": 2, "species_10040221": 3, "species_10091110": 1, "species_10091113": 4, "A6QR17": 6, "ENSBTAT00000015111": 2, "species_419305": 7, "reaction_10091275": 2, "species_10091269": 8, "species_10091273": 7, "reaction_10091260": 4, "species_10091252": 4, "species_10091257": 5, "reaction_10091271": 3, "reaction_10091151": 3, "species_10040243": 15, "species_10043033": 3, "ENSBTAT00000085237": 4, "species_10091149": 9, "A0A3Q1N508": 13, "reaction_10091156": 4, "species_10091153": 8, "reaction_10091118": 2, "species_10042685": 2, "ENSBTAT00000014920": 8, "species_10091011": 3, "reaction_10091267": 3, "species_10091263": 2, "ENSBTAT00000024297": 6, "species_10091265": 2, "species_10050265": 5, "ENSBTAT00000017629": 2, "reaction_10091158": 3, "species_5218688": 1, "species_10046309": 2, "reaction_10086662": 2, "species_10086658": 3, "species_10086660": 3, "reaction_10086575": 3, "species_10048262": 3, "ENSBTAT00000081022": 2, "species_10086571": 3, "F1MKP4": 3, "ENSBTAT00000025398": 1, "Q95MI6": 5, "ENSBTAT00000047063": 2, "species_10086573": 4, "A0A3Q1N5S8": 3, "reaction_10048270": 3, "species_10048266": 3, "species_10048268": 3, "reaction_10049681": 3, "species_10049677": 3, "A0A3Q1M8L4": 3, "ENSBTAT00000082095": 1, "A0A3Q1M0R0": 6, "ENSBTAT00000081916": 2, "species_10049679": 4, "reaction_10051907": 3, "species_10049671": 2, "species_10051903": 2, "ENSBTAT00000078403": 2, "species_10051905": 3, "A0A3Q1LQX2": 6, "reaction_10086565": 3, "species_10086561": 2, "ENSBTAT00000026905": 2, "species_10086563": 3, "A7MBA3": 2, "reaction_10048248": 3, "species_10048244": 2, "ENSBTAT00000000972": 7, "species_10048242": 2, "ENSBTAT00000006662": 2, "species_10048246": 3, "E1BAY1": 2, "P01272": 5, "reaction_10048282": 3, "species_10048278": 2, "ENSBTAT00000071185": 2, "species_10048274": 2, "ENSBTAT00000079270": 2, "species_10048280": 3, "A0A3Q1MB83": 2, "A0A3Q1M5G0": 2, "reaction_10048304": 3, "species_10048290": 2, "ENSBTAT00000017827": 2, "species_10048300": 3, "F1MIT6": 3, "ENSBTAT00000047461": 1, "F1MF07": 3, "ENSBTAT00000008625": 1, "species_10048302": 4, "P81401": 2, "reaction_10038918": 3, "species_10038912": 2, "ENSBTAT00000023275": 3, "species_10038908": 3, "species_10038916": 3, "A7MBH4": 6, "reaction_10048326": 3, "species_10048322": 3, "P58073": 3, "ENSBTAT00000043154": 1, "E1B9U9": 3, "ENSBTAT00000001408": 1, "species_10048312": 2, "ENSBTAT00000061196": 2, "species_10048324": 4, "E1B7Q8": 2, "reaction_10091763": 3, "species_10045862": 3, "ENSBTAT00000034352": 2, "species_9684615": 1, "species_10091761": 3, "A5PKG3": 6, "reaction_10047378": 3, "species_10045892": 3, "ENSBTAT00000008214": 2, "species_416372": 6, "CHEBI:15650": 8, "species_10046259": 5, "A2VEA2": 7, "reaction_10047396": 3, "species_10045934": 3, "Q3T181": 5, "ENSBTAT00000036478": 1, "F1MRY8": 5, "ENSBTAT00000054992": 1, "species_416436": 4, "species_10045936": 4, "reaction_10091812": 4, "species_10045864": 5, "reaction_10047398": 3, "species_10038914": 2, "species_10045866": 5, "reaction_10047374": 3, "species_416911": 8, "species_10047370": 2, "ENSBTAT00000008808": 2, "species_10047372": 3, "A0A452DI56": 2, "reaction_10047376": 3, "species_391930": 10, "species_10045990": 2, "ENSBTAT00000046806": 2, "species_10045992": 3, "F1MUY4": 4, "reaction_10047394": 3, "species_10047390": 3, "F1N2L8": 3, "ENSBTAT00000002800": 1, "F1MZJ8": 3, "ENSBTAT00000019930": 1, "species_10047392": 4, "reaction_10047380": 3, "species_391932": 11, "species_10045856": 3, "ENSBTAT00000019892": 2, "species_10045858": 3, "Q95125": 11, "reaction_10047366": 3, "species_10046263": 2, "ENSBTAT00000066986": 2, "species_10046265": 3, "A0A3Q1N2W9": 4, "reaction_10047364": 3, "species_416428": 4, "species_10046299": 2, "ENSBTAT00000005326": 2, "species_10046301": 3, "F1MCJ0": 4, "reaction_10049657": 3, "species_444840": 5, "species_5357505": 4, "species_193451": 6, "species_176655": 5, "CHEBI:16755": 5, "species_10049653": 2, "ENSBTAT00000005120": 2, "species_10049655": 6, "Q862A9": 2, "reaction_10047354": 3, "species_10047350": 5, "P01223": 4, "ENSBTAT00000008264": 2, "E1BD70": 3, "ENSBTAT00000009286": 1, "A0A0F7RPV8": 3, "ENSBTAT00000075524": 1, "species_10047338": 2, "ENSBTAT00000052615": 2, "species_10047352": 6, "F1N4F6": 2, "reaction_10047362": 3, "species_10047358": 2, "ENSBTAT00000022047": 2, "species_10047360": 4, "A0A140T893": 2, "reaction_10047334": 3, "species_10045798": 3, "Q0VBW7": 5, "ENSBTAT00000000188": 1, "A0A3Q1M7J7": 5, "ENSBTAT00000069568": 1, "species_10045788": 2, "ENSBTAT00000000559": 2, "species_10045800": 4, "P32236": 4, "reaction_10049659": 3, "species_3296262": 3, "CHEBI:20067": 4, "species_197230": 9, "species_10046459": 2, "ENSBTAT00000065393": 3, "species_10046461": 4, "G3N168": 5, "reaction_10048208": 3, "species_419777": 10, "species_10048204": 4, "Q9BGI7": 8, "ENSBTAT00000027054": 3, "P02699": 10, "ENSBTAT00000001730": 6, "P51490": 8, "ENSBTAT00000021912": 3, "species_10048206": 6, "reaction_10048214": 3, "species_10045850": 2, "ENSBTAT00000040059": 2, "species_10045852": 3, "E1BEK2": 4, "reaction_10045180": 3, "species_10045172": 2, "ENSBTAT00000013116": 2, "species_10045176": 2, "ENSBTAT00000026663": 2, "species_10045178": 3, "F1N2D2": 4, "E1BH62": 4, "reaction_10067358": 3, "species_10049514": 2, "ENSBTAT00000016850": 2, "species_10067354": 2, "ENSBTAT00000008096": 2, "species_10067356": 3, "Q0II78": 2, "Q3ZBN3": 4, "reaction_10045168": 3, "species_10045164": 2, "ENSBTAT00000028430": 2, "species_10045160": 3, "ENSBTAT00000037034": 2, "species_10045166": 3, "F1MT56": 5, "Q8SQB1": 4, "reaction_10045072": 3, "species_10045054": 2, "ENSBTAT00000082438": 2, "species_10045068": 4, "Q2HJ17": 5, "ENSBTAT00000010652": 1, "F1MP16": 5, "ENSBTAT00000001762": 1, "A6QLA5": 5, "ENSBTAT00000049352": 1, "species_10045070": 5, "O97919": 6, "reaction_10049520": 3, "species_10049510": 2, "ENSBTAT00000026082": 2, "species_10049516": 3, "Q1RMQ0": 6, "ENSBTAT00000007331": 2, "species_10049518": 4, "P35350": 2, "reaction_10045106": 3, "species_10045102": 2, "ENSBTAT00000078248": 2, "species_10045098": 2, "species_10045104": 3, "A4IF92": 4, "reaction_10045268": 3, "species_10045264": 2, "ENSBTAT00000077980": 2, "species_10045260": 3, "P25930": 7, "ENSBTAT00000001406": 1, "A4IF77": 5, "ENSBTAT00000024512": 1, "species_10045266": 4, "A0A3Q1M085": 6, "reaction_10083880": 3, "species_10046469": 2, "ENSBTAT00000047653": 2, "species_10045080": 2, "ENSBTAT00000020577": 2, "species_10046471": 3, "F6RDR3": 6, "E1BAG6": 4, "reaction_10045196": 3, "species_10045188": 2, "ENSBTAT00000020855": 2, "species_10045192": 2, "ENSBTAT00000024371": 2, "species_10045194": 3, "Q29RT9": 4, "Q5EA94": 4, "reaction_10045280": 3, "species_10045276": 2, "ENSBTAT00000019690": 2, "species_10045272": 2, "ENSBTAT00000075648": 2, "species_10045278": 3, "A9QWP9": 4, "Q5MD61": 4, "reaction_10049570": 3, "species_10049524": 2, "ENSBTAT00000068509": 2, "species_10049566": 12, "P28291": 3, "ENSBTAT00000013146": 1, "A5PKF1": 3, "ENSBTAT00000023564": 1, "Q17QA1": 5, "ENSBTAT00000009446": 1, "E1BGB8": 3, "ENSBTAT00000004257": 1, "P82943": 3, "ENSBTAT00000013399": 1, "A0A3Q1LTV3": 3, "ENSBTAT00000071668": 1, "A0A3Q1NB11": 3, "ENSBTAT00000085385": 1, "F1MYS4": 3, "ENSBTAT00000035430": 1, "Q9TTS6": 3, "ENSBTAT00000005406": 1, "F1MIF0": 3, "ENSBTAT00000001579": 1, "species_10049568": 13, "A0A3Q1LTZ4": 2, "reaction_10045156": 3, "species_10045142": 2, "ENSBTAT00000025420": 2, "species_10045152": 3, "F1MZ86": 5, "ENSBTAT00000019846": 1, "A6YT15": 5, "ENSBTAT00000002036": 1, "species_10045154": 4, "D9ZDE4": 4, "reaction_10049639": 3, "species_10046161": 2, "ENSBTAT00000011164": 2, "species_10046157": 2, "ENSBTAT00000063808": 2, "species_10046163": 3, "G3N3U0": 4, "Q56JW7": 4, "reaction_10045094": 3, "species_10045090": 2, "ENSBTAT00000079349": 2, "species_10045086": 4, "A0A3S5ZP45": 6, "ENSBTAT00000018066": 2, "A0JN72": 5, "ENSBTAT00000025880": 1, "species_10045092": 5, "A0A3Q1M976": 4, "reaction_10091037": 3, "species_9615246": 1, "species_10045250": 2, "ENSBTAT00000063575": 2, "species_10091035": 2, "P25104": 2, "reaction_10046731": 3, "species_10045814": 3, "ENSBTAT00000076190": 2, "species_10045810": 3, "F6PV87": 5, "ENSBTAT00000009443": 1, "F1ME85": 5, "ENSBTAT00000022994": 1, "species_10045816": 4, "A0A3Q1LXY0": 9, "reaction_10047483": 3, "species_10047479": 2, "ENSBTAT00000065044": 2, "species_10047481": 3, "P48044": 4, "reaction_10046733": 3, "species_10045970": 2, "ENSBTAT00000026346": 2, "species_10045966": 2, "ENSBTAT00000010554": 2, "species_10045972": 3, "P01175": 4, "P56449": 4, "reaction_10049661": 3, "species_10046036": 2, "ENSBTAT00000013959": 2, "species_10046032": 2, "ENSBTAT00000021097": 2, "species_10046038": 3, "Q8SPN1": 4, "F1MN36": 4, "reaction_10046729": 3, "species_10045940": 2, "ENSBTAT00000029067": 2, "species_10045944": 2, "ENSBTAT00000021612": 2, "species_10045946": 3, "F1N2X0": 4, "P08858": 4, "reaction_10045406": 3, "species_10045398": 3, "Q8MJV4": 5, "ENSBTAT00000018455": 1, "A0A3Q1LTH9": 5, "ENSBTAT00000078382": 1, "species_10045402": 2, "ENSBTAT00000021510": 2, "species_10045404": 4, "G5E5J0": 4, "reaction_10045362": 3, "species_10045358": 2, "ENSBTAT00000084136": 2, "species_10045354": 2, "ENSBTAT00000000695": 2, "species_10045360": 3, "O62647": 4, "A0A3Q1LWC2": 4, "reaction_10046773": 3, "species_10046769": 2, "species_10046767": 2, "ENSBTAT00000014661": 2, "species_10046771": 3, "P34974": 2, "P01190": 7, "reaction_10045332": 3, "species_10038198": 3, "species_10045328": 2, "ENSBTAT00000078035": 2, "species_10045330": 3, "A0A3Q1MXN7": 6, "reaction_10053335": 3, "species_10046114": 2, "ENSBTAT00000061371": 2, "species_10046110": 3, "F1MY53": 7, "ENSBTAT00000023519": 1, "A0A452DII4": 8, "ENSBTAT00000014782": 2, "species_10046116": 4, "E1BP23": 6, "reaction_10054775": 3, "species_10046102": 2, "ENSBTAT00000048447": 2, "species_10046098": 2, "species_10046104": 3, "A0A452DKE4": 6, "reaction_10046953": 3, "species_10045984": 4, "F1MCC4": 12, "ENSBTAT00000012283": 1, "F1N4J9": 7, "ENSBTAT00000026902": 4, "A4IFB7": 12, "ENSBTAT00000001191": 1, "species_10037577": 12, "A0A452DI66": 13, "ENSBTAT00000009406": 5, "species_10045986": 6, "reaction_10045384": 3, "species_10045366": 2, "ENSBTAT00000063299": 2, "species_10045380": 4, "E1BFV6": 5, "ENSBTAT00000008645": 1, "G3MWT4": 8, "ENSBTAT00000011728": 1, "F1MV99": 5, "ENSBTAT00000052225": 1, "species_10045382": 5, "G3N364": 4, "reaction_10046763": 3, "species_10046759": 5, "P47798": 3, "ENSBTAT00000032494": 1, "E1B8V8": 3, "ENSBTAT00000006185": 1, "Q9GLJ8": 3, "ENSBTAT00000026223": 1, "P56451": 3, "ENSBTAT00000012049": 1, "species_10046737": 2, "species_10046761": 6, "reaction_10049645": 3, "species_10046022": 2, "ENSBTAT00000067360": 2, "species_10046026": 2, "ENSBTAT00000018290": 2, "species_10046028": 3, "F1MJZ0": 4, "A0A3Q1MSN3": 4, "reaction_10049699": 3, "species_10049687": 2, "ENSBTAT00000020135": 2, "species_10049695": 2, "O77801": 3, "ENSBTAT00000027848": 1, "species_10049697": 3, "E1BKC2": 2, "reaction_10049683": 3, "species_10046333": 2, "ENSBTAT00000055041": 2, "species_10046329": 2, "F1MEV7": 5, "ENSBTAT00000036249": 1, "species_10046335": 3, "F1MSU3": 4, "reaction_10045292": 3, "species_10045284": 2, "ENSBTAT00000004179": 2, "species_10045288": 2, "ENSBTAT00000026275": 2, "species_10045290": 3, "P79255": 2, "F1N018": 2, "reaction_10045324": 3, "species_10045302": 3, "F1N083": 5, "ENSBTAT00000004157": 1, "Q2KIP6": 5, "ENSBTAT00000001209": 1, "species_10045320": 3, "species_10045322": 5, "reaction_10046735": 3, "species_10045876": 3, "P17322": 5, "ENSBTAT00000010649": 1, "Q867A9": 5, "ENSBTAT00000028571": 1, "species_10045886": 3, "P21450": 5, "ENSBTAT00000018173": 1, "P28088": 5, "ENSBTAT00000070002": 1, "species_10045888": 5, "reaction_10046915": 3, "species_10046293": 5, "B1H0W3": 5, "ENSBTAT00000022125": 1, "F1MKB6": 5, "ENSBTAT00000006247": 1, "A6QQX6": 5, "ENSBTAT00000057526": 1, "Q1RMU8": 5, "ENSBTAT00000087149": 1, "species_10046275": 2, "ENSBTAT00000062944": 2, "species_10046295": 6, "P51694": 4, "reaction_10046917": 3, "species_10045950": 2, "ENSBTAT00000006980": 2, "species_10045960": 3, "F1MWG2": 5, "ENSBTAT00000028963": 1, "E1BCZ7": 5, "ENSBTAT00000004808": 1, "species_10045962": 4, "P01156": 4, "reaction_10049637": 3, "species_10046006": 2, "ENSBTAT00000006982": 2, "species_10046002": 2, "ENSBTAT00000026634": 2, "species_10046018": 3, "O46639": 4, "A6QM11": 4, "reaction_10046919": 3, "species_10045902": 2, "ENSBTAT00000028248": 2, "species_10045898": 2, "ENSBTAT00000073562": 2, "species_10045904": 3, "A0A3Q1MXY0": 4, "E1BFS5": 4, "reaction_10045350": 3, "species_10045346": 2, "ENSBTAT00000039541": 2, "species_10045336": 2, "ENSBTAT00000026630": 2, "species_10045348": 3, "A0A452DJT3": 4, "A6QL98": 4, "reaction_10047864": 3, "species_10045826": 2, "ENSBTAT00000008730": 2, "species_417891": 14, "species_10045828": 3, "A6QL49": 4, "reaction_10047851": 3, "species_10045838": 2, "ENSBTAT00000004269": 2, "species_10045840": 3, "A4IFV1": 4, "reaction_10047866": 3, "species_417888": 4, "species_10045832": 2, "ENSBTAT00000057184": 2, "species_10045834": 3, "F1MTB2": 4, "reaction_10047853": 3, "species_114570": 2, "species_10045976": 2, "ENSBTAT00000018000": 2, "species_10045978": 3, "F1MU50": 4, "reaction_10047868": 3, "species_10046215": 2, "ENSBTAT00000054975": 2, "species_417877": 1, "species_10046217": 3, "species_29494": 9, "F1MDW9": 4, "reaction_10090956": 3, "species_9611319": 1, "species_10046221": 3, "ENSBTAT00000064076": 2, "species_10047855": 3, "Q0IIL0": 7, "reaction_10047870": 3, "species_114564": 2, "species_10045820": 2, "ENSBTAT00000001919": 2, "species_10045822": 3, "P48042": 4, "reaction_10047857": 4, "species_10046223": 3, "reaction_10047989": 3, "species_10045894": 3, "reaction_10047860": 3, "species_10045844": 2, "ENSBTAT00000011278": 2, "species_10045846": 3, "G3X6Q0": 4, "reaction_10047862": 3, "species_10046227": 2, "ENSBTAT00000027950": 2, "species_417855": 1, "species_10046229": 3, "Q3SX17": 4, "reaction_10047987": 3, "species_10046239": 3, "Q0VC81": 5, "ENSBTAT00000010057": 1, "P28190": 5, "ENSBTAT00000072690": 1, "species_83908": 2, "species_10046241": 4, "species_83909": 18, "reaction_10048003": 3, "species_10047999": 3, "Q1LZD0": 3, "ENSBTAT00000009974": 1, "E1BKU0": 3, "ENSBTAT00000077466": 1, "species_10048001": 5, "reaction_10078536": 5, "species_10078533": 2, "ENSBTAT00000025329": 1, "reaction_10048176": 3, "species_10045922": 5, "E1BLD8": 7, "ENSBTAT00000071208": 1, "F1MX11": 7, "ENSBTAT00000004931": 1, "Q3ZC80": 7, "ENSBTAT00000005968": 1, "A0A3Q1M9C6": 7, "ENSBTAT00000087152": 1, "species_10045924": 6, "reaction_10048180": 3, "species_10046319": 5, "F1ME98": 5, "ENSBTAT00000000492": 1, "F1MV28": 5, "ENSBTAT00000004608": 1, "A2VDV6": 5, "ENSBTAT00000003550": 1, "species_10046321": 6, "reaction_10049663": 3, "species_10046074": 5, "G3X6J0": 5, "ENSBTAT00000007420": 1, "Q1JQB3": 5, "ENSBTAT00000024480": 1, "A7MB13": 5, "ENSBTAT00000016931": 1, "O46685": 5, "ENSBTAT00000008858": 1, "species_10046076": 6, "reaction_10084702": 3, "species_9023982": 3, "CHEBI:81559": 2, "species_9022660": 3, "species_10084698": 2, "ENSBTAT00000029488": 2, "species_10084700": 4, "B9VR26": 2, "reaction_10051217": 3, "species_517533": 4, "species_10046339": 2, "ENSBTAT00000007469": 2, "species_10046341": 3, "Q3T0E9": 4, "reaction_10048178": 3, "species_444560": 3, "species_426030": 6, "species_10046255": 3, "E1B9P2": 5, "ENSBTAT00000025809": 1, "A0A3Q1LGC0": 5, "ENSBTAT00000067697": 1, "species_10046257": 5, "reaction_10053333": 3, "species_561075": 2, "species_10046447": 2, "ENSBTAT00000035454": 2, "species_10046449": 3, "F1MYN3": 4, "reaction_10067350": 3, "species_433123": 1, "species_10046441": 2, "ENSBTAT00000068791": 2, "species_10046443": 3, "A0A3Q1M1U4": 4, "species_113536": 5, "reaction_10049641": 3, "species_10046134": 2, "ENSBTAT00000065884": 2, "species_158417": 10, "species_10046136": 3, "G3MWJ9": 4, "reaction_10048172": 3, "species_419339": 4, "species_10046269": 2, "ENSBTAT00000068939": 2, "species_10046271": 3, "A0A3Q1MJK4": 4, "reaction_10081580": 3, "species_6805204": 2, "species_10081576": 2, "ENSBTAT00000021281": 2, "species_10081578": 3, "F1N600": 2, "reaction_10067362": 3, "species_3296330": 3, "CHEBI:37098": 4, "species_10046463": 2, "species_10046465": 4, "reaction_10067364": 3, "species_10046453": 2, "ENSBTAT00000001202": 2, "species_373863": 9, "species_10046455": 3, "B9UM28": 4, "reaction_10048174": 3, "species_419375": 4, "species_10045996": 2, "ENSBTAT00000038757": 2, "species_10045998": 3, "Q9TTY5": 8, "reaction_10083937": 3, "species_8851675": 1, "species_10046483": 2, "ENSBTAT00000007471": 2, "species_10046485": 3, "Q1RMI1": 4, "species_192184": 4, "reaction_10049643": 3, "species_10046501": 3, "F1N5V2": 5, "ENSBTAT00000038240": 1, "A0A3Q1NND8": 5, "ENSBTAT00000084207": 1, "species_444679": 5, "CHEBI:32111": 4, "species_188980": 5, "species_5696361": 5, "CHEBI:16296": 4, "species_10046503": 7, "reaction_10045138": 3, "species_10045134": 7, "E1BAB4": 5, "ENSBTAT00000001415": 1, "A0A3Q1LJN2": 5, "ENSBTAT00000072365": 1, "A5D7D8": 5, "ENSBTAT00000025275": 1, "E1B965": 5, "ENSBTAT00000018119": 1, "E1BLE8": 5, "ENSBTAT00000017342": 1, "F1MDE0": 7, "ENSBTAT00000085376": 2, "species_10045136": 8, "reaction_10067348": 3, "species_10046435": 18, "F1MVK0": 5, "ENSBTAT00000045470": 1, "A0A3Q1N090": 5, "ENSBTAT00000071230": 1, "F1MP17": 5, "ENSBTAT00000001761": 1, "Q2ABB3": 5, "ENSBTAT00000043009": 1, "A0A3Q1LRA2": 5, "ENSBTAT00000079249": 1, "A0A3Q1N0Q7": 5, "ENSBTAT00000082851": 1, "F1MZD2": 5, "ENSBTAT00000033179": 1, "A0A3Q1ML22": 5, "ENSBTAT00000071900": 1, "F1N2G6": 5, "ENSBTAT00000043010": 1, "Q2ABB1": 5, "ENSBTAT00000031637": 1, "Q2ABC5": 5, "ENSBTAT00000046105": 1, "E1B8B7": 5, "ENSBTAT00000055191": 1, "Q2ABC4": 5, "ENSBTAT00000022454": 1, "Q2ABC0": 5, "ENSBTAT00000042999": 1, "A0A3Q1LZA1": 5, "ENSBTAT00000076866": 1, "A0A3Q1MIP5": 5, "ENSBTAT00000071184": 1, "Q2ABC3": 5, "ENSBTAT00000024537": 1, "species_3296423": 44, "CHEBI:3193": 4, "species_76328": 6, "CHEBI:3768": 4, "CHEBI:10093": 4, "CHEBI:17814": 4, "species_40727": 5, "CHEBI:8206": 4, "CHEBI:48923": 4, "CHEBI:28973": 4, "CHEBI:73228": 4, "CHEBI:23359": 4, "CHEBI:28241": 4, "CHEBI:73226": 4, "CHEBI:73224": 4, "CHEBI:65408": 4, "CHEBI:3944": 4, "CHEBI:73235": 4, "CHEBI:73231": 4, "CHEBI:16226": 4, "CHEBI:27613": 4, "CHEBI:5547": 4, "CHEBI:2825": 4, "CHEBI:73232": 4, "CHEBI:18305": 4, "CHEBI:3445": 4, "CHEBI:36773": 4, "CHEBI:2622": 4, "CHEBI:73237": 4, "CHEBI:2366": 4, "CHEBI:3941": 4, "CHEBI:7939": 4, "CHEBI:351346": 4, "CHEBI:8692": 4, "CHEBI:73239": 4, "CHEBI:15854": 6, "CHEBI:9162": 4, "CHEBI:26948": 4, "CHEBI:50042": 4, "CHEBI:69236": 4, "CHEBI:73222": 4, "CHEBI:17698": 4, "CHEBI:73236": 4, "CHEBI:2853": 4, "species_10046437": 61, "reaction_10089211": 3, "species_10039640": 7, "Q3ZCA7": 15, "ENSBTAT00000017303": 1, "P63097": 15, "ENSBTAT00000003515": 1, "A7MBH9": 15, "ENSBTAT00000027511": 1, "G1K1V2": 16, "ENSBTAT00000023234": 1, "species_10089193": 14, "O46471": 10, "ENSBTAT00000005642": 1, "A0A3Q1MFC7": 4, "ENSBTAT00000075674": 1, "E1B7H3": 4, "ENSBTAT00000037643": 1, "E1BMB5": 8, "ENSBTAT00000048654": 1, "A7MBG6": 10, "ENSBTAT00000012221": 1, "F1MMH1": 4, "ENSBTAT00000022048": 1, "F1MUR0": 7, "ENSBTAT00000028880": 1, "F1N7R3": 8, "ENSBTAT00000005904": 1, "P79348": 7, "ENSBTAT00000004487": 1, "E1BIV2": 4, "ENSBTAT00000011200": 1, "A0A3Q1N2W6": 7, "ENSBTAT00000070104": 1, "E1BH23": 7, "ENSBTAT00000054620": 1, "species_10089209": 19, "reaction_10089197": 3, "species_10089195": 19, "species_10039660": 7, "reaction_10088940": 4, "species_10088932": 7, "species_10088937": 8, "reaction_10088942": 3, "species_10088935": 2, "reaction_10089214": 3, "reaction_10048370": 5, "species_10048361": 8, "P63212": 21, "ENSBTAT00000003959": 1, "P04695": 3, "ENSBTAT00000023990": 3, "species_10048367": 8, "reaction_10037037": 4, "species_10037034": 3, "A0A3Q1N6Q5": 3, "ENSBTAT00000072751": 1, "F1N5T6": 3, "ENSBTAT00000014100": 1, "reaction_10039658": 3, "species_10039620": 4, "A0A3Q1M3D6": 8, "ENSBTAT00000079386": 1, "species_10039655": 9, "reaction_10039674": 3, "species_10039669": 8, "reaction_10039667": 4, "reaction_10039671": 3, "species_10039646": 4, "reaction_10036959": 5, "species_114520": 11, "species_10036956": 7, "A0A3Q1LVV4": 5, "ENSBTAT00000074229": 2, "reaction_10037045": 5, "species_10036942": 2, "reaction_10039676": 3, "species_10039644": 13, "species_10039662": 12, "reaction_10039664": 4, "reaction_10039651": 3, "species_10039648": 12, "reaction_10039653": 3, "species_10039642": 10, "reaction_10046534": 5, "species_10046509": 197, "species_10046513": 197, "species_10046532": 3, "A0A3Q1MMQ2": 2, "ENSBTAT00000081300": 1, "A0A3Q1MKT3": 2, "ENSBTAT00000078547": 1, "reaction_10089224": 3, "species_10089219": 13, "F1N3V3": 5, "ENSBTAT00000026460": 1, "species_10089199": 10, "species_10037355": 5, "reaction_10047979": 3, "species_10047977": 4, "reaction_10048632": 3, "species_10048628": 3, "A0A3Q1M4W2": 4, "ENSBTAT00000077611": 1, "A0A3Q1LTG6": 4, "ENSBTAT00000070979": 1, "species_114519": 7, "species_10048630": 5, "reaction_10048543": 3, "species_10048539": 4, "F1MY82": 3, "ENSBTAT00000004240": 1, "E1BMG4": 13, "ENSBTAT00000060978": 2, "species_10048541": 5, "reaction_10048587": 6, "species_422506": 2, "species_10048584": 2, "ENSBTAT00000073448": 2, "reaction_10048580": 4, "species_426026": 1, "species_10048577": 3, "E1BBV2": 2, "ENSBTAT00000018523": 1, "F6RA94": 2, "ENSBTAT00000012173": 1, "reaction_10076743": 6, "species_5694509": 1, "species_10076740": 2, "ENSBTAT00000022100": 1, "reaction_10048660": 5, "species_10048657": 6, "F1MCG9": 2, "ENSBTAT00000031198": 1, "A0A3Q1NJA6": 2, "ENSBTAT00000066461": 1, "E1BGA9": 2, "ENSBTAT00000022905": 1, "A0A3Q1LYT4": 2, "ENSBTAT00000075621": 1, "A0A3Q1N4W0": 2, "ENSBTAT00000080144": 1, "reaction_10037549": 3, "species_10037544": 6, "species_10037546": 7, "reaction_10047823": 3, "species_10047819": 3, "species_10047821": 6, "reaction_10064910": 3, "species_10040201": 4, "species_10064908": 4, "reaction_10064915": 5, "species_10064912": 6, "reaction_10064919": 3, "reaction_10089203": 3, "species_10089201": 13, "reaction_10046149": 5, "species_10046140": 126, "B5U8Y5": 3, "ENSBTAT00000014446": 1, "Q9BDJ6": 3, "ENSBTAT00000016350": 10, "CHEBI:28716": 3, "CHEBI:28875": 4, "CHEBI:53460": 3, "CHEBI:27997": 3, "species_9024011": 9, "CHEBI:53487": 3, "CHEBI:53486": 3, "species_8934421": 5, "species_9608444": 7, "CHEBI:28661": 3, "species_2026977": 7, "E1BKC0": 4, "ENSBTAT00000000560": 1, "species_10046142": 126, "species_10046146": 4, "reaction_10089222": 3, "reaction_10047947": 4, "species_10047944": 9, "A0A3Q1MZ56": 3, "ENSBTAT00000078870": 1, "A0A3Q1MW13": 3, "ENSBTAT00000079827": 1, "E1BPD8": 3, "ENSBTAT00000021805": 1, "A0A3Q1M3R2": 2, "ENSBTAT00000085287": 1, "A0A3Q1M5L1": 2, "ENSBTAT00000082666": 1, "reaction_10089226": 3, "species_10083948": 6, "E1BP29": 3, "ENSBTAT00000061163": 2, "species_10083941": 3, "species_10084012": 5, "reaction_10089228": 3, "species_10083943": 6, "reaction_10091247": 4, "species_10091244": 2, "ENSBTAT00000072849": 1, "reaction_10083951": 4, "reaction_10084016": 3, "species_10047876": 4, "ENSBTAT00000050078": 2, "species_10084014": 5, "G3X811": 5, "reaction_10092055": 4, "species_10092052": 2, "reaction_10047498": 5, "species_10047495": 4, "A0A3Q1M2L5": 7, "ENSBTAT00000080364": 1, "E1BCV1": 7, "ENSBTAT00000007845": 1, "reaction_10043315": 3, "species_10037311": 2, "species_10043313": 3, "reaction_10088962": 3, "species_10047596": 2, "species_10048105": 3, "ENSBTAT00000083031": 2, "species_10088960": 3, "A0A3Q1LKT5": 4, "reaction_10051656": 4, "species_10051649": 7, "A0A3Q1MM27": 8, "ENSBTAT00000074311": 1, "species_10051653": 7, "reaction_10047468": 3, "species_10047464": 4, "species_10047466": 7, "reaction_10089167": 3, "species_10089163": 5, "species_10089165": 7, "reaction_10089217": 3, "species_10089205": 7, "reaction_10089207": 3, "species_10051645": 3, "reaction_10048170": 5, "species_10047839": 4, "species_10047841": 4, "species_10048167": 27, "E1B9G8": 2, "ENSBTAT00000014311": 1, "A0A3Q1MA97": 2, "ENSBTAT00000081198": 1, "A0A3Q1LXW7": 2, "ENSBTAT00000081961": 1, "A0A3Q1MA22": 3, "ENSBTAT00000069238": 1, "G5E6P3": 9, "ENSBTAT00000062941": 1, "Q58CS5": 2, "ENSBTAT00000009131": 1, "A0A3Q1N5H1": 2, "ENSBTAT00000068004": 1, "reaction_10047552": 3, "species_10047548": 2, "species_10047544": 5, "E1BIL1": 4, "ENSBTAT00000023757": 1, "species_10047550": 5, "reaction_10051667": 4, "species_10051664": 7, "species_10051660": 7, "reaction_10037330": 5, "species_10037327": 5, "reaction_10037332": 3, "species_10037325": 2, "species_10037321": 3, "reaction_10047956": 2, "species_10047953": 4, "reaction_10072123": 3, "species_10072119": 3, "ENSBTAT00000075908": 2, "species_10072115": 3, "species_10072121": 5, "A0A3Q1LM07": 2, "reaction_10072154": 3, "species_10072144": 2, "E1BE57": 3, "ENSBTAT00000017670": 1, "species_10072148": 2, "species_10072152": 2, "ENSBTAT00000064817": 4, "reaction_10072220": 6, "species_10072079": 6, "A6H727": 11, "ENSBTAT00000008704": 1, "F1MCY1": 11, "ENSBTAT00000015510": 1, "A0A3Q1MDV1": 6, "ENSBTAT00000068810": 2, "species_10072165": 6, "species_10072218": 5, "E1BKE3": 5, "ENSBTAT00000035821": 2, "A0A3Q1MNB3": 2, "ENSBTAT00000078675": 1, "Q32KR5": 2, "ENSBTAT00000087155": 1, "A0A452DIR3": 2, "ENSBTAT00000007606": 1, "species_10072197": 4, "E1BBF8": 2, "ENSBTAT00000025532": 1, "F1MDL2": 2, "ENSBTAT00000017038": 1, "species_10072183": 4, "F6RVK1": 2, "ENSBTAT00000049437": 1, "A0A3Q1LTC8": 2, "ENSBTAT00000082308": 1, "reaction_10072081": 3, "species_10072077": 2, "species_10072073": 3, "reaction_10072138": 4, "species_10072130": 3, "species_10072135": 3, "reaction_10072199": 5, "species_10072173": 4, "species_10072187": 2, "ENSBTAT00000036487": 1, "reaction_10072713": 3, "species_10072710": 4, "Q0VCW1": 3, "ENSBTAT00000007660": 1, "species_10072708": 4, "reaction_10072715": 3, "reaction_10072685": 3, "species_10072669": 3, "species_10072681": 2, "ENSBTAT00000022205": 2, "species_10072683": 4, "E1BPQ8": 2, "reaction_10072606": 2, "species_10072602": 3, "species_10072604": 2, "reaction_10072720": 3, "species_10072718": 3, "G3N1D5": 2, "reaction_10072677": 2, "species_10072675": 3, "species_10072663": 3, "reaction_10074038": 5, "species_10074035": 67, "A0A3Q1LI10": 5, "ENSBTAT00000073047": 1, "E1BMN5": 5, "ENSBTAT00000007787": 1, "F1MKE9": 5, "ENSBTAT00000006213": 1, "F1MMQ8": 5, "ENSBTAT00000061417": 1, "A0A3Q1LNC8": 9, "ENSBTAT00000066559": 1, "A0A452DJB1": 2, "ENSBTAT00000044847": 1, "A0A452DHX3": 19, "ENSBTAT00000003498": 2, "F1N5N3": 4, "ENSBTAT00000021391": 1, "F1MP52": 6, "ENSBTAT00000015112": 1, "F6S0Q2": 22, "ENSBTAT00000006816": 1, "E1BKU1": 22, "ENSBTAT00000000528": 1, "F1MS00": 26, "ENSBTAT00000000744": 2, "A0A3Q1N8H3": 25, "ENSBTAT00000083411": 2, "A0A3Q1M0Y1": 23, "ENSBTAT00000081398": 1, "E1BD76": 21, "ENSBTAT00000023553": 2, "E1BCL0": 21, "ENSBTAT00000027984": 2, "G3MZM3": 22, "ENSBTAT00000066172": 2, "A0A3Q1LSU3": 3, "ENSBTAT00000068365": 1, "A0A3Q1N010": 2, "ENSBTAT00000084300": 1, "reaction_10091515": 6, "species_10039726": 5, "species_8848337": 2, "species_10091512": 3, "species_10091502": 4, "A0A3Q1M5Z8": 3, "ENSBTAT00000081950": 1, "A7MBG2": 3, "ENSBTAT00000008957": 1, "species_10091504": 4, "reaction_10091458": 6, "species_10091448": 3, "species_10091454": 4, "species_10077880": 4, "G3N1V4": 3, "ENSBTAT00000064297": 1, "species_10091456": 3, "reaction_10091490": 5, "species_10091477": 4, "species_10091487": 3, "Q5EA55": 4, "ENSBTAT00000069302": 1, "Q58DA8": 2, "ENSBTAT00000075844": 1, "reaction_10091506": 3, "species_9647934": 1, "reaction_10091479": 2, "reaction_10091527": 3, "reaction_10074088": 5, "species_10074042": 11, "A0A452DI16": 9, "ENSBTAT00000006653": 1, "A0A3Q1LQP3": 17, "ENSBTAT00000074936": 1, "A0A3Q1M888": 17, "ENSBTAT00000079194": 1, "A0A3Q1M353": 31, "ENSBTAT00000086962": 2, "species_10074065": 6, "species_10074085": 1, "reaction_10073930": 5, "species_10073919": 5, "species_10073927": 5, "reaction_10073917": 3, "species_10073913": 4, "species_10073915": 5, "reaction_10073932": 3, "species_10073925": 3, "reaction_10091548": 3, "species_9657579": 1, "species_10074135": 10, "reaction_10073921": 3, "species_10073869": 4, "reaction_10073904": 4, "species_10073896": 3, "species_10073898": 7, "species_10073902": 2, "ENSBTAT00000070853": 1, "reaction_10073872": 4, "species_10073863": 4, "reaction_10074050": 4, "species_10074040": 5, "species_10074048": 5, "A6H716": 4, "ENSBTAT00000001552": 2, "reaction_10073940": 3, "species_10073938": 5, "species_10073936": 3, "reaction_10073942": 5, "reaction_10074184": 3, "species_10074180": 2, "ENSBTAT00000071243": 2, "species_10074182": 4, "A0A3Q1M5M4": 2, "reaction_10074221": 3, "species_10074213": 7, "species_10074217": 2, "ENSBTAT00000024107": 2, "species_10074219": 7, "P13696": 2, "reaction_10074156": 3, "species_10074144": 6, "species_10074153": 5, "reaction_10074238": 5, "species_10074225": 7, "species_10074235": 2, "ENSBTAT00000010538": 1, "reaction_10074146": 3, "species_10074046": 3, "reaction_10074148": 3, "reaction_10074231": 5, "species_10074229": 6, "reaction_10091534": 2, "reaction_10091580": 3, "species_10091578": 7, "reaction_10074137": 6, "species_10074123": 11, "Q0VD16": 15, "ENSBTAT00000048212": 1, "A0A3S5ZPX3": 15, "ENSBTAT00000011377": 1, "species_10074114": 13, "species_10074125": 12, "reaction_10091576": 3, "species_10074118": 11, "species_9657577": 1, "species_10091574": 10, "reaction_10074129": 7, "species_10074127": 11, "species_10074121": 11, "reaction_10091568": 3, "species_9657567": 1, "reaction_10074176": 4, "species_10074172": 7, "Q0VCN2": 3, "ENSBTAT00000082130": 1, "species_10074174": 7, "reaction_10074195": 4, "species_10074190": 4, "E1BP15": 3, "ENSBTAT00000060984": 1, "species_10074192": 4, "reaction_10091570": 3, "species_9657570": 1, "reaction_10091572": 3, "species_9657574": 1, "reaction_10091595": 3, "species_10091591": 3, "species_10091589": 3, "A0A3Q1NAC7": 3, "ENSBTAT00000076160": 1, "A0A3Q1M6Z6": 4, "ENSBTAT00000087412": 2, "species_10091593": 5, "reaction_10091529": 4, "reaction_10075256": 3, "species_10075220": 5, "F1MVV5": 8, "ENSBTAT00000013073": 1, "G5E577": 10, "ENSBTAT00000007709": 2, "F1MH23": 8, "ENSBTAT00000012303": 6, "species_10075236": 4, "species_10075202": 4, "reaction_10075260": 2, "species_10075208": 2, "species_10075258": 2, "reaction_10075262": 2, "species_10075234": 3, "species_10075226": 2, "reaction_10075251": 2, "species_10075241": 4, "species_10075249": 4, "reaction_10075218": 3, "species_10066851": 2, "species_10075214": 3, "species_10075216": 5, "reaction_10075253": 3, "reaction_10075223": 4, "reaction_10075916": 4, "species_10075904": 4, "Q3MI00": 5, "ENSBTAT00000036270": 2, "species_10075913": 3, "reaction_10076193": 3, "species_10076189": 2, "ENSBTAT00000075652": 2, "species_10076185": 2, "species_10076191": 4, "A0A3Q1MTC5": 3, "reaction_10075906": 3, "species_10067944": 2, "reaction_10075205": 5, "species_10075194": 3, "species_10047654": 4, "A0A3Q1M0G8": 8, "ENSBTAT00000082239": 1, "A0A3Q1LSY0": 8, "ENSBTAT00000085260": 1, "reaction_10076229": 5, "species_10042661": 3, "ENSBTAT00000061127": 5, "species_10076226": 2, "species_10066865": 2, "reaction_10075239": 5, "species_10075232": 2, "reaction_10076198": 4, "species_10076195": 3, "reaction_10039690": 3, "species_10039686": 2, "species_10039688": 5, "reaction_10090954": 4, "species_10090951": 6, "species_10090933": 6, "reaction_10039711": 3, "species_10039703": 5, "species_10039709": 6, "reaction_10039697": 4, "species_10039694": 4, "reaction_10090944": 4, "species_10090935": 8, "species_10090937": 9, "reaction_10090949": 4, "species_10090946": 8, "reaction_10039592": 5, "species_10039587": 3, "species_10039589": 3, "species_10039579": 7, "reaction_10039581": 2, "reaction_10039601": 4, "species_10039598": 4, "reaction_10074879": 3, "species_10073958": 4, "species_10073960": 6, "reaction_10039736": 3, "species_10039732": 2, "species_10039734": 5, "reaction_10040570": 5, "species_10040546": 2, "species_10040551": 3, "species_10040567": 4, "reaction_10090994": 4, "species_10090982": 2, "ENSBTAT00000008295": 2, "species_10090978": 2, "ENSBTAT00000019612": 2, "species_10090990": 2, "G3N0C9": 3, "ENSBTAT00000064240": 1, "species_10090992": 4, "F1N3F6": 2, "Q1RMU0": 2, "reaction_10041851": 5, "species_10041848": 6, "reaction_10041869": 3, "species_10041865": 5, "species_10041867": 8, "reaction_10041917": 2, "species_10041913": 2, "species_10041915": 2, "reaction_10040489": 3, "species_10040476": 3, "species_10040480": 3, "species_10040486": 3, "A0A3Q1MCD7": 2, "ENSBTAT00000077745": 2, "reaction_10040495": 4, "species_10040493": 2, "reaction_10090722": 3, "species_10090663": 5, "Q08DT3": 6, "ENSBTAT00000013493": 1, "species_10090411": 2, "species_10090720": 5, "reaction_10090727": 4, "species_10090724": 4, "reaction_10090666": 4, "species_10090654": 3, "reaction_10090675": 3, "species_10090673": 4, "reaction_10073244": 3, "species_10040423": 6, "species_10073210": 16, "reaction_10073215": 3, "species_10073212": 18, "reaction_10057337": 3, "species_10057334": 6, "Q08E39": 15, "ENSBTAT00000002324": 3, "A0A3Q1MJ84": 8, "ENSBTAT00000079589": 2, "A0A3Q1MJY7": 8, "Q0P594": 8, "ENSBTAT00000012182": 1, "P67774": 8, "ENSBTAT00000000596": 1, "species_10057300": 7, "reaction_10057323": 3, "species_10057316": 9, "species_10057321": 8, "reaction_10053082": 3, "species_10053077": 4, "species_10053079": 7, "reaction_10057327": 3, "species_10057325": 5, "reaction_10057329": 4, "species_10053062": 5, "reaction_10057314": 3, "species_10057312": 3, "species_10057310": 2, "species_10057306": 2, "reaction_10059156": 4, "reaction_10057302": 2, "species_10053066": 7, "reaction_10057318": 6, "species_10040307": 4, "species_10053072": 6, "reaction_10040761": 4, "species_10040755": 2, "species_10036461": 6, "species_10040759": 9, "reaction_10040779": 4, "species_10036473": 8, "reaction_10083933": 5, "species_735700": 6, "species_10083928": 2, "species_10083930": 3, "species_10052428": 2, "ENSBTAT00000018541": 2, "reaction_10083935": 2, "species_10036373": 2, "reaction_10040782": 4, "species_10040751": 12, "species_10036485": 11, "reaction_10040753": 4, "species_10040747": 2, "species_10036475": 9, "reaction_10073240": 5, "species_10065247": 17, "reaction_10073192": 3, "species_10073188": 17, "species_10035515": 5, "species_10073190": 19, "reaction_10073237": 5, "reaction_10073177": 3, "species_10073168": 16, "species_10073170": 17, "reaction_10073166": 4, "species_10073161": 14, "species_10073163": 14, "reaction_10073182": 5, "species_10073179": 18, "reaction_10073184": 3, "reaction_10073028": 5, "species_10073023": 16, "species_10065243": 15, "species_10073026": 15, "reaction_10073031": 3, "reaction_10073175": 4, "species_10073172": 17, "reaction_10087367": 5, "reaction_10072939": 3, "species_10072924": 16, "reaction_10072927": 4, "species_10072922": 17, "reaction_10072933": 4, "reaction_10073246": 3, "species_10073186": 16, "species_10073217": 19, "reaction_10073222": 3, "species_10073219": 21, "reaction_10040776": 4, "species_10040767": 14, "species_10036502": 13, "reaction_10040769": 4, "species_10036500": 11, "species_10040763": 3, "reaction_10057704": 5, "species_10036498": 2, "species_10036506": 2, "species_10057702": 6, "reaction_10057707": 4, "species_10036508": 4, "reaction_10040720": 4, "species_10036438": 10, "species_10040706": 2, "species_10040718": 13, "reaction_10040788": 4, "species_10036459": 12, "reaction_10040744": 5, "species_10036405": 6, "species_10040722": 2, "species_10040734": 9, "species_10040742": 6, "Q9MZ06": 2, "ENSBTAT00000044642": 2, "reaction_10040785": 4, "species_10036432": 8, "reaction_10073328": 3, "species_10040740": 2, "species_10040736": 4, "reaction_10072909": 4, "species_10072904": 19, "species_10072906": 18, "reaction_10072929": 3, "species_10065255": 19, "reaction_10072931": 4, "reaction_10073001": 3, "species_10072988": 18, "species_10072990": 20, "reaction_10073004": 4, "species_10072997": 18, "reaction_10072993": 5, "reaction_10072999": 3, "reaction_10073129": 3, "species_10065257": 19, "species_10073124": 19, "reaction_10087370": 5, "species_10065259": 20, "reaction_10073133": 3, "species_10073131": 20, "reaction_10072976": 5, "species_10072961": 18, "species_10072974": 17, "reaction_10073136": 5, "reaction_10072979": 3, "reaction_10073127": 4, "reaction_10073231": 5, "species_10065263": 20, "reaction_10073208": 3, "species_10073203": 21, "species_10073205": 23, "reaction_10073242": 3, "reaction_10073071": 3, "species_10073053": 3, "F1MQI5": 4, "ENSBTAT00000039444": 1, "species_10073067": 3, "A0A3Q1MP99": 3, "ENSBTAT00000068413": 1, "F1MH60": 3, "ENSBTAT00000046117": 1, "species_10073069": 4, "reaction_10073077": 4, "species_10073073": 6, "species_10073075": 8, "reaction_10073199": 3, "species_10073194": 20, "species_10073196": 22, "reaction_10073201": 3, "species_10065249": 17, "reaction_10040794": 4, "species_10040702": 12, "species_10036379": 11, "reaction_10040704": 4, "species_10036375": 9, "species_10040698": 3, "reaction_10040696": 4, "species_10040690": 2, "species_10036328": 5, "species_10040694": 8, "reaction_10040791": 4, "species_10036344": 7, "reaction_10040860": 4, "species_10040771": 6, "species_10036399": 5, "reaction_10040773": 4, "species_10036397": 3, "reaction_10073097": 4, "species_10073094": 15, "species_10072950": 15, "reaction_10073113": 4, "species_10073104": 18, "species_10073110": 18, "reaction_10073083": 3, "species_10065233": 19, "species_10073079": 17, "reaction_10072957": 5, "species_10072954": 19, "reaction_10087373": 5, "reaction_10073090": 4, "species_10065235": 16, "reaction_10073106": 3, "species_10072952": 17, "reaction_10073108": 3, "reaction_10073225": 5, "species_10065239": 18, "reaction_10073115": 3, "species_10065251": 18, "species_10065253": 20, "reaction_10073228": 5, "reaction_10073087": 3, "species_10073085": 17, "reaction_10073119": 3, "species_10073099": 17, "species_10073117": 19, "reaction_10073102": 4, "reaction_10073122": 5, "reaction_10073326": 3, "species_10073322": 4, "F1N0R7": 3, "ENSBTAT00000004298": 1, "G3MY74": 3, "ENSBTAT00000065908": 1, "F1MVT1": 3, "ENSBTAT00000028517": 1, "species_10073324": 18, "reaction_10072937": 4, "species_10072915": 18, "reaction_10072920": 4, "species_10072917": 17, "reaction_10072935": 3, "reaction_10091689": 3, "species_9674079": 1, "species_10040472": 3, "A0A3Q1ME99": 3, "ENSBTAT00000067659": 1, "A0A3Q1N3Z8": 3, "ENSBTAT00000086976": 1, "species_10091687": 3, "reaction_10046666": 2, "species_10046658": 3, "E1BJY4": 5, "ENSBTAT00000061070": 2, "species_10046664": 3, "reaction_10046677": 4, "species_10046672": 2, "species_10046670": 2, "species_10046674": 3, "A0A452DIF6": 8, "ENSBTAT00000001642": 2, "reaction_10046660": 2, "species_10046654": 2, "reaction_10057850": 4, "species_10043813": 10, "species_10057847": 9, "reaction_10057854": 3, "species_10057840": 8, "species_10057852": 9, "reaction_10057872": 5, "species_10057869": 10, "reaction_10058480": 3, "species_10058476": 9, "reaction_10091667": 3, "species_10043782": 3, "species_9669722": 1, "species_10091665": 2, "reaction_10057845": 3, "species_10043807": 8, "species_10043809": 9, "reaction_10043832": 3, "species_10043828": 9, "F1MRH8": 7, "ENSBTAT00000012781": 1, "species_10043830": 10, "reaction_10057867": 4, "species_10057864": 7, "species_10043826": 7, "reaction_10058474": 4, "species_10058471": 9, "reaction_10058478": 2, "reaction_10057857": 5, "species_10043817": 4, "reaction_10043815": 3, "species_10043811": 3, "reaction_10091751": 3, "species_9674322": 1, "species_10091749": 2, "reaction_10057862": 4, "species_10057859": 7, "reaction_10041657": 3, "species_10041653": 2, "ENSBTAT00000026471": 2, "species_10041655": 3, "E1BMX5": 10, "reaction_10041649": 2, "species_10041441": 2, "reaction_10070651": 5, "species_10070647": 3, "species_10070649": 3, "species_10070580": 7, "E1BLY9": 5, "ENSBTAT00000034285": 1, "reaction_10070589": 4, "species_10070586": 5, "reaction_10070657": 5, "species_10070655": 3, "reaction_10070628": 4, "species_10070612": 4, "species_10070626": 5, "reaction_10070615": 4, "reaction_10069535": 4, "species_10069530": 4, "A7Z041": 7, "ENSBTAT00000046702": 1, "species_10069532": 5, "reaction_10071504": 4, "species_10071501": 6, "A0A3Q1MRN2": 5, "ENSBTAT00000075025": 2, "species_10070638": 6, "reaction_10071506": 3, "species_10071499": 2, "reaction_10070645": 5, "species_10070642": 8, "reaction_10071508": 3, "species_10070640": 8, "reaction_10070676": 3, "species_10047604": 2, "species_10070672": 5, "Q1LZB2": 5, "ENSBTAT00000024518": 1, "species_10070674": 6, "reaction_10070624": 4, "species_10070619": 5, "species_10070621": 5, "reaction_10070594": 4, "species_10070591": 4, "species_10070578": 5, "reaction_10070596": 3, "reaction_10056781": 3, "species_10056771": 3, "species_10056765": 2, "species_10056779": 5, "reaction_10057151": 2, "species_10057149": 5, "reaction_10057166": 4, "reaction_10057184": 5, "species_10057181": 5, "reaction_10090971": 3, "species_10057248": 5, "species_10057211": 7, "species_10057250": 4, "reaction_10057262": 3, "species_10057257": 4, "Q32PG0": 3, "ENSBTAT00000020867": 2, "species_10057259": 6, "reaction_10057264": 3, "species_10055126": 2, "species_10057255": 2, "reaction_10057272": 3, "species_10057268": 3, "ENSBTAT00000086215": 2, "species_10057270": 3, "A0A3Q1LVN4": 3, "reaction_10057298": 2, "species_10057296": 2, "reaction_10057236": 3, "species_10057201": 2, "species_10057233": 6, "A0A3Q1LNM1": 2, "ENSBTAT00000068424": 1, "A0A3Q1MBH7": 2, "ENSBTAT00000086383": 1, "A0A3Q1MDC6": 4, "ENSBTAT00000075241": 1, "Q5G235": 2, "ENSBTAT00000024745": 1, "reaction_10057252": 3, "species_10057246": 2, "reaction_10057284": 2, "species_10057278": 4, "species_10057282": 3, "reaction_10057286": 3, "reaction_10084080": 4, "species_10084065": 4, "E1BCZ6": 5, "ENSBTAT00000020028": 1, "E1BDW7": 5, "ENSBTAT00000030663": 1, "species_10084077": 3, "reaction_10084067": 3, "species_10080868": 4, "species_10080866": 3, "reaction_10080870": 3, "species_10080858": 2, "reaction_10091705": 3, "species_10091695": 3, "ENSBTAT00000005126": 2, "species_10091703": 3, "Q3SZK1": 3, "reaction_10040393": 3, "species_10040366": 10, "species_10040388": 11, "reaction_10040458": 4, "species_10040455": 10, "species_10040395": 11, "reaction_10040460": 3, "species_10040449": 4, "reaction_10040447": 3, "species_10040440": 10, "A6QLQ1": 5, "ENSBTAT00000028307": 1, "species_10040444": 14, "reaction_10040462": 4, "species_10040382": 3, "reaction_10040369": 4, "species_10040361": 9, "reaction_10040432": 4, "species_10040425": 12, "species_10040430": 2, "ENSBTAT00000061187": 1, "reaction_10040451": 3, "reaction_10040386": 3, "species_10040374": 2, "species_10040384": 4, "reaction_10040453": 3, "reaction_10040421": 3, "species_10040417": 3, "Q08DX1": 3, "ENSBTAT00000018755": 1, "A0A3Q1M839": 3, "ENSBTAT00000073657": 1, "species_10040419": 11, "reaction_10040331": 5, "species_10040301": 11, "reaction_10040303": 3, "species_10040283": 9, "reaction_10040286": 4, "species_10040256": 9, "reaction_10040258": 3, "reaction_10040289": 4, "species_10040227": 9, "reaction_10036616": 3, "species_10035489": 4, "reaction_10040317": 5, "species_10040314": 10, "reaction_10040326": 3, "reaction_10040323": 4, "species_10040223": 6, "species_10040225": 8, "species_10040321": 2, "ENSBTAT00000030750": 1, "reaction_10040229": 2, "reaction_10044472": 3, "species_10044467": 9, "reaction_10044465": 3, "species_10043197": 4, "species_10044463": 9, "reaction_10044470": 4, "reaction_10040310": 5, "reaction_10035536": 3, "species_10035532": 3, "species_10035534": 4, "reaction_10075065": 3, "species_10036626": 4, "species_10036624": 4, "reaction_10075097": 3, "species_10036628": 5, "reaction_10083487": 3, "species_10083485": 3, "reaction_10083565": 5, "species_10083556": 6, "Q32KY4": 15, "ENSBTAT00000079975": 1, "A0A452DIV3": 17, "ENSBTAT00000023277": 4, "A6QLS3": 12, "species_10083562": 4, "reaction_10083558": 3, "species_10083554": 4, "reaction_10083646": 3, "species_10083642": 2, "ENSBTAT00000079568": 3, "species_10083644": 4, "A0A3Q1M4A0": 2, "reaction_10083632": 5, "reaction_10083652": 5, "species_10083649": 2, "reaction_10083638": 3, "species_10083635": 2, "reaction_10083690": 5, "species_10083682": 4, "species_10083687": 4, "reaction_10083581": 3, "species_10070667": 2, "ENSBTAT00000024101": 4, "species_10083579": 4, "F1MFD1": 3, "reaction_10083629": 5, "species_10083620": 4, "A0A3Q1MQ07": 2, "ENSBTAT00000073322": 3, "species_10083626": 2, "reaction_10083695": 4, "species_10083692": 5, "reaction_10083697": 3, "reaction_10083588": 5, "species_10083585": 2, "reaction_10083684": 3, "species_10083680": 2, "reaction_10083622": 3, "species_10083618": 2, "reaction_10083707": 5, "species_10083700": 2, "species_10083704": 2, "ENSBTAT00000002574": 1, "reaction_10083726": 3, "species_10055952": 4, "ENSBTAT00000008678": 2, "species_10083724": 4, "A6QQN2": 4, "reaction_10083729": 5, "reaction_10090428": 5, "species_10090425": 7, "F1MEQ7": 5, "ENSBTAT00000010781": 1, "reaction_10089841": 3, "species_10047493": 4, "species_10089837": 6, "species_10089839": 7, "reaction_10090501": 4, "species_10090415": 5, "reaction_10073851": 4, "species_10039143": 19, "F1N197": 5, "ENSBTAT00000007575": 2, "species_10073848": 16, "reaction_10046572": 3, "species_10042890": 7, "reaction_10046588": 3, "reaction_10046583": 5, "species_10042880": 6, "species_10046580": 2, "ENSBTAT00000024128": 1, "reaction_10049894": 5, "species_10039178": 15, "reaction_10088493": 3, "species_10039075": 2, "species_10039119": 11, "species_10039121": 12, "reaction_10073853": 3, "species_10039145": 2, "species_10039147": 16, "reaction_10088496": 3, "species_428011": 1, "reaction_10039059": 4, "species_10039055": 3, "species_10039057": 5, "reaction_10039209": 5, "species_10039204": 2, "ENSBTAT00000023487": 2, "species_10039207": 2, "species_10039168": 4, "ENSBTAT00000022415": 2, "reaction_10039160": 3, "species_10039133": 4, "Q0P5A7": 3, "ENSBTAT00000039828": 3, "A0A3Q1NEI6": 5, "ENSBTAT00000068997": 2, "species_10034357": 3, "species_10039131": 2, "reaction_10091741": 3, "species_9678687": 1, "species_10039151": 3, "ENSBTAT00000010928": 2, "species_10039153": 4, "P18203": 3, "reaction_10039180": 8, "species_10039164": 2, "reaction_10039200": 5, "species_10034529": 3, "A0A3Q1N412": 13, "ENSBTAT00000019214": 2, "E1B8K9": 13, "species_10039197": 3, "reaction_10039155": 8, "species_10034363": 4, "reaction_10072900": 3, "species_10039101": 3, "species_10039115": 4, "species_10039117": 7, "reaction_10073844": 3, "species_10039141": 15, "species_10037666": 4, "reaction_10039127": 3, "species_10039123": 13, "reaction_10072902": 3, "species_10039095": 5, "reaction_10046602": 4, "species_10046594": 3, "F1MM00": 3, "ENSBTAT00000022347": 2, "species_10046599": 2, "reaction_10046604": 2, "species_10046592": 2, "reaction_10085865": 3, "species_10085861": 2, "ENSBTAT00000065187": 2, "species_10085857": 2, "ENSBTAT00000015193": 2, "species_10085863": 3, "Q8SQ19": 2, "E1BPS0": 2, "reaction_10060285": 5, "species_2105007": 1, "species_2104997": 1, "species_1606845": 6, "species_10060282": 2, "F1MU84": 4, "ENSBTAT00000006001": 1, "reaction_10091293": 5, "species_2105012": 3, "species_2105010": 2, "species_1605658": 6, "species_10059946": 4, "H7BWW2": 6, "ENSBTAT00000048411": 1, "reaction_10060293": 5, "species_2104995": 1, "species_10060290": 2, "ENSBTAT00000023218": 2, "reaction_10060295": 5, "species_10059941": 6, "Q0V8R6": 3, "ENSBTAT00000017261": 1, "reaction_10063510": 2, "species_10063483": 4, "Q05443": 11, "ENSBTAT00000002279": 1, "P13605": 11, "ENSBTAT00000019854": 1, "species_10060854": 3, "reaction_10038201": 4, "species_10038157": 5, "Q3T0B6": 6, "ENSBTAT00000013734": 1, "species_10038196": 3, "species_10038188": 3, "reaction_10091546": 2, "species_10091544": 2, "species_10038209": 4, "reaction_10038205": 4, "species_10038143": 2, "species_10038203": 2, "species_10038145": 4, "reaction_10090718": 3, "species_9603327": 1, "species_10038217": 3, "reaction_10038129": 3, "species_10037535": 4, "F1N1G4": 4, "ENSBTAT00000019525": 1, "E1BG29": 4, "ENSBTAT00000017571": 1, "E1B863": 4, "ENSBTAT00000055945": 1, "species_10038121": 2, "A0A3Q1LT55": 4, "ENSBTAT00000087456": 1, "species_10038127": 6, "reaction_10091600": 2, "species_10076686": 2, "species_10038115": 2, "reaction_10091671": 3, "species_10071934": 3, "species_10091669": 2, "species_10071930": 2, "reaction_10038166": 3, "species_10038147": 5, "species_10038163": 2, "F1MAU4": 6, "ENSBTAT00000047906": 1, "reaction_10090185": 3, "species_9603311": 1, "species_10038215": 3, "reaction_10071946": 2, "species_10038174": 2, "reaction_10038221": 6, "species_10038182": 5, "species_10037829": 6, "species_10037843": 7, "CHEBI:18085": 2, "Q8HZY1": 3, "ENSBTAT00000011485": 1, "species_10038219": 3, "reaction_10038149": 3, "species_10038133": 2, "reaction_10038213": 3, "species_10038211": 3, "reaction_10035301": 3, "species_10035297": 2, "ENSBTAT00000006308": 2, "species_10035293": 11, "Q1RMP0": 4, "ENSBTAT00000045075": 1, "Q32P78": 7, "ENSBTAT00000043971": 1, "Q3SZ29": 4, "ENSBTAT00000016250": 1, "A7YWA1": 4, "ENSBTAT00000047621": 1, "E1BIX2": 4, "ENSBTAT00000008496": 1, "Q3ZBC0": 7, "ENSBTAT00000030510": 1, "F6QVL1": 4, "ENSBTAT00000032261": 1, "A6QLS0": 4, "ENSBTAT00000018830": 1, "Q32L22": 4, "ENSBTAT00000025246": 1, "F2Z4H3": 7, "ENSBTAT00000000606": 1, "species_10035299": 12, "E1B883": 2, "reaction_10035254": 5, "species_73682": 1, "species_10035051": 2, "ENSBTAT00000034806": 2, "species_10035053": 2, "F1MCZ7": 2, "species_10035231": 7, "species_10035252": 8, "G5E683": 2, "ENSBTAT00000053498": 2, "reaction_10034224": 5, "species_10034221": 2, "P37980": 2, "ENSBTAT00000010311": 1, "reaction_10050169": 5, "species_159450": 8, "species_10050166": 2, "A0A3Q1LXA8": 2, "ENSBTAT00000086411": 1, "species_109496": 2, "reaction_10038107": 3, "species_10038103": 3, "ENSBTAT00000005581": 5, "species_10038105": 3, "Q3SYU2": 6, "reaction_10038082": 3, "species_10034837": 47, "A0A452DJF6": 10, "ENSBTAT00000055065": 1, "Q9XSI3": 10, "ENSBTAT00000020266": 1, "Q861S4": 10, "ENSBTAT00000002160": 1, "A0A3Q1LR67": 10, "ENSBTAT00000071569": 1, "Q3T003": 10, "ENSBTAT00000021033": 1, "E1BII3": 10, "ENSBTAT00000037203": 1, "P61257": 10, "ENSBTAT00000016378": 1, "Q3T057": 10, "ENSBTAT00000004190": 1, "P61356": 10, "ENSBTAT00000023183": 1, "Q862I1": 10, "ENSBTAT00000017905": 1, "P39872": 10, "ENSBTAT00000004188": 1, "Q58DT1": 10, "ENSBTAT00000026826": 1, "A0A452DIZ2": 10, "ENSBTAT00000027850": 1, "Q58DQ3": 10, "ENSBTAT00000033359": 1, "Q5E9E6": 10, "ENSBTAT00000025963": 1, "Q3T0S6": 10, "ENSBTAT00000037367": 1, "A0A3Q1M4M0": 10, "ENSBTAT00000036905": 1, "Q2TBQ5": 10, "ENSBTAT00000015358": 1, "P61284": 10, "ENSBTAT00000009155": 1, "G8JKV5": 10, "ENSBTAT00000084955": 1, "Q3SYR7": 10, "ENSBTAT00000019298": 1, "A0A3Q1LH67": 9, "ENSBTAT00000035330": 2, "A0A3Q1LST0": 10, "ENSBTAT00000020729": 2, "Q5EAD6": 10, "Q3T171": 10, "ENSBTAT00000075433": 1, "E1BHM9": 10, "ENSBTAT00000015544": 1, "Q3MIC0": 10, "ENSBTAT00000071825": 1, "P79244": 10, "ENSBTAT00000006781": 1, "Q58DW0": 10, "ENSBTAT00000006866": 1, "F1MDN4": 10, "ENSBTAT00000055086": 1, "Q32PB9": 10, "ENSBTAT00000042547": 1, "Q58DW5": 10, "ENSBTAT00000002626": 1, "P42899": 10, "ENSBTAT00000002326": 1, "Q56K14": 10, "ENSBTAT00000024376": 1, "A0A452DJ34": 10, "ENSBTAT00000031754": 1, "Q56K03": 10, "ENSBTAT00000066379": 1, "F1MG09": 10, "ENSBTAT00000050149": 2, "Q3SZ59": 10, "Q3T0D5": 10, "ENSBTAT00000069699": 1, "Q58DW3": 10, "ENSBTAT00000024788": 1, "Q3SZQ6": 10, "ENSBTAT00000020323": 1, "Q3T051": 10, "ENSBTAT00000087168": 1, "Q3MHM7": 10, "ENSBTAT00000004161": 1, "F1ML72": 10, "ENSBTAT00000071912": 1, "species_10038080": 45, "species_10034641": 2, "reaction_10034365": 3, "species_10034361": 2, "reaction_10034855": 5, "species_10034839": 88, "Q3T0F4": 11, "ENSBTAT00000020719": 1, "Q32PD5": 11, "ENSBTAT00000032643": 2, "E1BHA5": 11, "Q3T0V4": 11, "ENSBTAT00000018491": 1, "Q76I82": 11, "ENSBTAT00000069480": 1, "A0A3Q1LLI8": 11, "ENSBTAT00000072836": 1, "Q56JV9": 11, "ENSBTAT00000013079": 1, "Q3T0X6": 11, "ENSBTAT00000028093": 1, "P62276": 11, "ENSBTAT00000077396": 1, "Q3T169": 11, "ENSBTAT00000003962": 1, "A0A3Q1MFH1": 11, "ENSBTAT00000084646": 1, "A0A3Q1LRX4": 11, "ENSBTAT00000085499": 2, "A0A3Q1MIM5": 11, "Q56JX6": 11, "ENSBTAT00000003201": 1, "Q56JU9": 11, "ENSBTAT00000073736": 1, "F1MR01": 11, "ENSBTAT00000075650": 2, "A0A3Q1LNR2": 11, "Q56JX5": 11, "ENSBTAT00000040046": 1, "Q2KHT7": 11, "ENSBTAT00000018414": 1, "Q56JX8": 11, "ENSBTAT00000055693": 1, "A0A3Q1M5N2": 11, "ENSBTAT00000085238": 1, "E1BEQ3": 11, "ENSBTAT00000063143": 2, "Q3T199": 11, "Q32PB8": 11, "ENSBTAT00000027713": 1, "A0A3Q1M9K1": 11, "ENSBTAT00000082341": 2, "A0A3Q1LNI8": 11, "E1B7E5": 11, "ENSBTAT00000080007": 3, "E1BCB7": 11, "ENSBTAT00000025298": 1, "A0A3Q1LNV2": 11, "A0A3Q1MSH8": 11, "A2VE06": 11, "ENSBTAT00000063866": 6, "G3N267": 11, "E1BGR7": 11, "F1MJH2": 11, "P79103": 11, "ENSBTAT00000025024": 1, "A0A3Q1LQD0": 11, "G3N0K3": 11, "A0A3Q1MBL4": 11, "ENSBTAT00000020462": 1, "Q3ZBH8": 11, "ENSBTAT00000025484": 1, "species_10034853": 3, "ENSBTAT00000023455": 2, "species_10034609": 43, "reaction_10034905": 3, "species_10034901": 52, "E1B7R4": 3, "ENSBTAT00000061515": 1, "E1BLZ8": 3, "ENSBTAT00000049219": 1, "A7MB16": 3, "ENSBTAT00000084055": 1, "Q3T0V3": 3, "ENSBTAT00000014888": 1, "Q5E966": 3, "ENSBTAT00000077067": 1, "Q3ZCK1": 3, "ENSBTAT00000014281": 1, "Q3T122": 3, "ENSBTAT00000037985": 1, "Q3SYW6": 3, "ENSBTAT00000023384": 1, "Q32LC3": 3, "species_10034385": 6, "Q2KHU8": 6, "ENSBTAT00000019064": 1, "P68102": 6, "ENSBTAT00000071779": 1, "A0A3Q1LQI5": 6, "ENSBTAT00000086329": 1, "species_10034903": 56, "reaction_10034383": 3, "species_10034379": 5, "species_10034381": 6, "reaction_10034387": 4, "species_72393": 1, "reaction_10060894": 3, "species_10060890": 88, "species_10060888": 6, "Q2T9U1": 3, "ENSBTAT00000025405": 1, "E1BB38": 3, "ENSBTAT00000014015": 1, "A6QQL9": 7, "ENSBTAT00000019085": 1, "A0A3Q1LYQ7": 3, "ENSBTAT00000076619": 1, "Q3ZBG7": 3, "ENSBTAT00000017007": 1, "species_10060892": 93, "reaction_10048380": 2, "species_10048376": 2, "species_10048378": 2, "reaction_10046723": 8, "species_10046709": 2, "species_10046626": 2, "species_10046721": 4, "E1B8Q3": 2, "ENSBTAT00000026313": 1, "A0A3Q1NGS8": 5, "ENSBTAT00000082648": 1, "species_10046717": 4, "G5E5H9": 2, "ENSBTAT00000019647": 1, "CHEBI:71466": 2, "species_10046130": 16, "species_70115": 15, "reaction_10045736": 5, "species_10045700": 2, "ENSBTAT00000014462": 2, "species_10041260": 5, "species_10045702": 3, "P04837": 2, "species_10045734": 4, "E1B7M7": 3, "ENSBTAT00000025401": 1, "E1BFT5": 3, "ENSBTAT00000008663": 1, "species_10045722": 5, "P07994": 2, "ENSBTAT00000013154": 1, "reaction_10045694": 3, "species_10043952": 2, "species_10043954": 5, "reaction_10045744": 3, "species_10045740": 2, "species_10045742": 3, "reaction_10045696": 3, "species_10041265": 2, "reaction_10091056": 5, "species_9619052": 1, "species_8878776": 2, "species_9619021": 1, "species_10076366": 2, "F1MTP2": 3, "ENSBTAT00000032461": 1, "reaction_10048461": 3, "species_10048434": 2, "species_10048438": 2, "species_10048458": 5, "P67810": 2, "ENSBTAT00000014925": 1, "Q2KI36": 2, "ENSBTAT00000015866": 1, "A0A3Q1MLX7": 2, "ENSBTAT00000083476": 1, "E1BEI2": 2, "ENSBTAT00000008726": 1, "reaction_10048429": 9, "species_10048421": 2, "species_10048413": 2, "species_10048423": 2, "species_10046085": 2, "species_10048427": 3, "ENSBTAT00000082606": 2, "species_422024": 1, "reaction_10048465": 4, "species_422042": 1, "species_10048398": 3, "species_10048463": 2, "species_10048404": 3, "ENSBTAT00000000986": 1, "reaction_10048407": 4, "species_422019": 1, "species_10048400": 2, "reaction_10049385": 3, "species_216785": 2, "species_10049382": 2, "ENSBTAT00000001343": 1, "reaction_10049392": 3, "species_10049389": 2, "ENSBTAT00000086579": 1, "reaction_10085101": 7, "species_10040838": 8, "species_10085076": 3, "species_10085098": 4, "G3N2U5": 2, "ENSBTAT00000064999": 1, "A7E2Z5": 2, "ENSBTAT00000017043": 1, "E1BKB4": 2, "ENSBTAT00000069658": 1, "reaction_10085250": 7, "species_10085237": 3, "species_10085247": 3, "F1N325": 2, "ENSBTAT00000034047": 1, "G3N3S4": 2, "ENSBTAT00000065735": 1, "reaction_10087993": 3, "species_10087978": 27, "E1BJ64": 13, "ENSBTAT00000028591": 4, "Q1RMW1": 4, "ENSBTAT00000037020": 2, "A0A3Q1MTL8": 5, "ENSBTAT00000087337": 1, "Q2KII4": 16, "ENSBTAT00000078734": 3, "A0A3Q1MXH0": 8, "ENSBTAT00000068692": 2, "Q3SZ32": 16, "ENSBTAT00000026036": 3, "Q0P5F4": 8, "ENSBTAT00000002831": 2, "E1BHZ2": 7, "ENSBTAT00000024202": 1, "Q3MHZ2": 7, "ENSBTAT00000022024": 1, "A0A3Q1MJT8": 7, "ENSBTAT00000070334": 1, "F1MWW0": 7, "ENSBTAT00000011810": 1, "A0A3Q1M5W3": 7, "ENSBTAT00000075739": 1, "E1BJ12": 7, "ENSBTAT00000025032": 1, "F1MTH7": 7, "ENSBTAT00000001270": 1, "F1N349": 7, "ENSBTAT00000002623": 1, "E1BKN8": 8, "ENSBTAT00000023144": 2, "A7MBH6": 7, "ENSBTAT00000044628": 1, "A0A452DJ71": 7, "ENSBTAT00000038842": 1, "H7BWV6": 7, "ENSBTAT00000009484": 1, "Q2HJ53": 7, "ENSBTAT00000030652": 1, "E1BCM1": 7, "ENSBTAT00000069213": 1, "E1B9S2": 7, "ENSBTAT00000013884": 1, "E1BEH6": 7, "ENSBTAT00000004378": 1, "E1BKE5": 7, "ENSBTAT00000064207": 1, "species_10087990": 26, "species_10087869": 3, "reaction_10087848": 6, "species_10075935": 5, "species_10087835": 3, "A0A3Q1MJI4": 5, "ENSBTAT00000077128": 1, "E1B8X4": 5, "ENSBTAT00000013367": 1, "species_10087845": 6, "reaction_10087883": 3, "species_10087871": 6, "species_10087880": 3, "reaction_10087885": 3, "species_10087850": 5, "reaction_10087852": 6, "reaction_10088734": 3, "species_10088730": 2, "ENSBTAT00000013112": 3, "species_10088728": 16, "A0A3Q1LKZ4": 8, "ENSBTAT00000072958": 1, "A0A3Q1MNL1": 8, "ENSBTAT00000086637": 1, "A0A452DJ09": 8, "ENSBTAT00000028740": 1, "Q32L87": 3, "ENSBTAT00000004550": 1, "F1MYV7": 3, "ENSBTAT00000019879": 1, "F1MVI8": 3, "ENSBTAT00000028594": 1, "A0A3Q1LPL4": 3, "ENSBTAT00000070605": 1, "G3MXE6": 3, "ENSBTAT00000015886": 1, "E1BMD0": 3, "ENSBTAT00000010105": 1, "A0A3Q1MY43": 3, "ENSBTAT00000086238": 1, "A0A3Q1LT78": 3, "ENSBTAT00000084712": 1, "Q5E9A9": 3, "ENSBTAT00000022696": 1, "F1N3H0": 3, "ENSBTAT00000086437": 1, "species_10088732": 17, "A7MBJ5": 8, "reaction_10087825": 3, "species_10075937": 4, "A0A3Q1MIW5": 3, "ENSBTAT00000079440": 2, "species_10075927": 2, "reaction_10088688": 3, "species_10076087": 3, "species_10088684": 63, "A6QPV4": 3, "ENSBTAT00000006480": 1, "Q29RM5": 3, "ENSBTAT00000004519": 1, "F1N162": 3, "ENSBTAT00000011028": 1, "A7MB89": 3, "ENSBTAT00000011464": 1, "A0A3Q1N1L9": 8, "ENSBTAT00000073772": 1, "Q58D00": 8, "ENSBTAT00000085937": 1, "A0A452DHW1": 8, "ENSBTAT00000003178": 1, "A0A3Q1MN48": 8, "ENSBTAT00000078511": 1, "A5PKK2": 8, "ENSBTAT00000052368": 1, "E1BK68": 8, "ENSBTAT00000016959": 1, "F6PQR5": 9, "ENSBTAT00000046646": 1, "A7MBH8": 8, "ENSBTAT00000086266": 1, "A0A3Q1LNU6": 8, "ENSBTAT00000085125": 1, "Q2KHT6": 8, "ENSBTAT00000021554": 1, "A0A452DI01": 8, "ENSBTAT00000003249": 1, "F1N1C5": 8, "ENSBTAT00000019285": 1, "F1N019": 11, "ENSBTAT00000004177": 3, "A0A3Q1MDP9": 8, "ENSBTAT00000067912": 1, "A0A3Q1MCW5": 8, "ENSBTAT00000083919": 1, "A0A3Q1LQM8": 8, "ENSBTAT00000080785": 1, "A7MB09": 18, "ENSBTAT00000018036": 1, "A0A3Q1MLW5": 8, "ENSBTAT00000080771": 1, "A6QP22": 8, "ENSBTAT00000025095": 1, "A5PJX0": 8, "ENSBTAT00000003665": 1, "E1B9Q3": 8, "ENSBTAT00000001868": 1, "A0A3Q1LFJ4": 8, "ENSBTAT00000086616": 1, "A0A452DIC0": 8, "ENSBTAT00000012776": 1, "F1MDA7": 8, "ENSBTAT00000027498": 1, "A0A3Q1M118": 11, "ENSBTAT00000075176": 1, "F1MSC9": 8, "ENSBTAT00000082146": 1, "A0A3Q1M680": 8, "ENSBTAT00000080715": 1, "A0A452DIA2": 8, "ENSBTAT00000011600": 1, "E1BGE6": 8, "ENSBTAT00000050675": 1, "Q17QK6": 8, "ENSBTAT00000009501": 1, "F1MLX8": 8, "ENSBTAT00000003367": 1, "species_10088686": 64, "reaction_10088787": 5, "species_10088761": 2, "ENSBTAT00000018046": 2, "species_10088764": 2, "species_10088774": 4, "E1BM39": 3, "ENSBTAT00000026522": 1, "species_10088785": 6, "F6R7X9": 2, "ENSBTAT00000024194": 1, "E1BK00": 2, "ENSBTAT00000061262": 1, "reaction_10088807": 4, "species_10088802": 60, "species_10088804": 25, "species_10084815": 10, "A0A3Q1ME43": 5, "ENSBTAT00000071522": 1, "G3X736": 5, "ENSBTAT00000025677": 1, "F6QE33": 5, "ENSBTAT00000014754": 1, "Q2KI56": 5, "ENSBTAT00000069661": 1, "Q3SZA0": 5, "ENSBTAT00000009128": 1, "F1MBP8": 5, "ENSBTAT00000003609": 1, "A4FV74": 5, "ENSBTAT00000007696": 1, "reaction_10075942": 4, "species_10075933": 3, "species_10075939": 2, "reaction_10038457": 5, "species_8855657": 1, "species_8855661": 1, "species_29416": 5, "species_10038454": 2, "ENSBTAT00000017653": 1, "reaction_10038464": 5, "species_8855663": 1, "species_162872": 1, "species_8855667": 1, "species_10038461": 2, "ENSBTAT00000012921": 1, "reaction_10052665": 5, "species_10052629": 12, "A0A3Q1M6U9": 19, "ENSBTAT00000075287": 1, "A0A3Q1LPY0": 19, "ENSBTAT00000066675": 1, "A0A3Q1M633": 19, "ENSBTAT00000072582": 1, "A0A3Q1N072": 19, "ENSBTAT00000071114": 1, "G5E5A7": 19, "ENSBTAT00000010897": 1, "A0A3Q1LQ52": 19, "ENSBTAT00000085382": 1, "A0A3Q1M2T0": 19, "ENSBTAT00000083797": 1, "species_10052652": 10, "species_10052662": 3, "Q7YQE1": 2, "ENSBTAT00000079217": 2, "A0A3Q1MUB2": 2, "ENSBTAT00000076540": 1, "reaction_10052521": 4, "species_10052400": 15, "species_10052519": 8, "reaction_10077688": 5, "species_10077681": 8, "species_10077685": 2, "ENSBTAT00000022569": 1, "reaction_10052461": 5, "species_10052377": 8, "species_10052458": 12, "A0A3Q1MQ00": 2, "ENSBTAT00000071740": 1, "A0A3Q1M986": 2, "ENSBTAT00000078875": 1, "E1BPR6": 2, "ENSBTAT00000061536": 1, "E1BDW8": 2, "ENSBTAT00000028329": 1, "E1BBP1": 2, "E1BHN6": 2, "ENSBTAT00000010847": 1, "A6QLX6": 2, "ENSBTAT00000077005": 1, "E1BKQ9": 2, "ENSBTAT00000023104": 1, "Q07537": 2, "ENSBTAT00000081582": 1, "A0A3Q1LM69": 2, "ENSBTAT00000087139": 1, "F6QA59": 2, "ENSBTAT00000023106": 1, "reaction_10052716": 5, "species_10052569": 9, "species_10052713": 8, "species_10052656": 2, "reaction_10052606": 5, "species_10052603": 8, "A0A3Q1MPZ8": 2, "ENSBTAT00000078680": 1, "A7YY64": 3, "ENSBTAT00000024024": 1, "F1MGN7": 2, "ENSBTAT00000063600": 1, "A0A3Q1LX89": 3, "ENSBTAT00000084108": 1, "A0A3Q1LVP5": 3, "ENSBTAT00000079485": 1, "F1MSS4": 3, "ENSBTAT00000005494": 1, "Q0VC83": 2, "ENSBTAT00000021344": 1, "reaction_10054575": 5, "species_10054573": 9, "reaction_10054766": 5, "species_10054701": 9, "species_10054759": 8, "species_10054763": 2, "reaction_10054722": 5, "reaction_10054773": 5, "species_10054770": 2, "reaction_10054550": 5, "species_10054548": 8, "reaction_10052496": 4, "species_10052494": 8, "reaction_10061538": 5, "species_10061535": 3, "Q0VC84": 2, "ENSBTAT00000068688": 1, "Q3SX46": 2, "ENSBTAT00000028542": 1, "reaction_10052546": 4, "species_10052544": 8, "reaction_10052690": 4, "species_10052688": 8, "reaction_10076773": 5, "species_10076766": 8, "species_10076770": 2, "ENSBTAT00000001899": 1, "reaction_10070145": 5, "species_10070064": 6, "F1MXR3": 3, "ENSBTAT00000081541": 1, "F1MVP0": 3, "ENSBTAT00000020085": 1, "A0A3Q1MX27": 3, "ENSBTAT00000086844": 1, "A0A3Q1M2R9": 7, "ENSBTAT00000085538": 1, "E1BK41": 3, "ENSBTAT00000061071": 1, "species_173594": 1, "species_158602": 5, "species_10070138": 6, "species_10070142": 2, "ENSBTAT00000047526": 1, "reaction_10077897": 5, "species_6788865": 3, "CHEBI:87176": 1, "CHEBI:87177": 1, "species_6788858": 3, "CHEBI:87180": 1, "CHEBI:87179": 1, "species_10077894": 2, "ENSBTAT00000020456": 1, "reaction_10077883": 5, "species_6788753": 1, "species_6788758": 1, "reaction_10038408": 2, "species_10038406": 2, "A0A452DIP8": 10, "ENSBTAT00000021789": 2, "species_10038394": 2, "reaction_10038416": 2, "species_10038412": 2, "ENSBTAT00000009746": 3, "species_10038414": 2, "reaction_10038438": 2, "species_10038436": 2, "species_10038384": 2, "reaction_10043698": 8, "species_10043683": 4, "Q6EWQ7": 4, "ENSBTAT00000084447": 1, "F1MN49": 4, "ENSBTAT00000079770": 1, "species_204628": 1, "species_204635": 5, "species_10043689": 3, "species_10043695": 2, "Q6EWQ6": 2, "ENSBTAT00000008200": 1, "reaction_10043717": 8, "species_10043708": 3, "species_10043714": 3, "Q0VC53": 2, "ENSBTAT00000006935": 1, "reaction_10060109": 6, "species_10060079": 10, "F1N665": 3, "ENSBTAT00000014061": 1, "Q148F3": 3, "ENSBTAT00000026877": 1, "A0A3Q1LZ44": 4, "ENSBTAT00000081469": 1, "A6QLZ3": 8, "ENSBTAT00000010988": 1, "G3N2T7": 3, "ENSBTAT00000072310": 1, "A0A3Q1LGQ6": 3, "ENSBTAT00000080500": 1, "E1BIN3": 3, "ENSBTAT00000017050": 1, "A5D7J7": 3, "ENSBTAT00000050377": 1, "E1BKH3": 3, "ENSBTAT00000023672": 1, "species_1663154": 1, "species_10060106": 10, "species_10060045": 2, "ENSBTAT00000055237": 1, "reaction_10091630": 5, "species_10091620": 2, "species_10091628": 2, "species_10088614": 3, "ENSBTAT00000000502": 1, "reaction_10071579": 5, "species_10071569": 2, "species_10071572": 2, "species_10071576": 2, "ENSBTAT00000025327": 1, "reaction_10071566": 7, "species_10071559": 2, "species_31633": 16, "species_10071563": 2, "ENSBTAT00000055382": 1, "reaction_10066409": 3, "species_10066405": 2, "ENSBTAT00000023029": 2, "species_10066407": 2, "species_10066369": 6, "E1BAI5": 2, "ENSBTAT00000002296": 1, "A0A3Q1MTU0": 2, "ENSBTAT00000080821": 1, "A0A3Q1MFX1": 2, "ENSBTAT00000078136": 1, "reaction_10066380": 3, "species_10066376": 2, "ENSBTAT00000081472": 2, "species_10066378": 2, "reaction_10066372": 3, "species_10066355": 5, "reaction_10077406": 3, "species_10056739": 2, "species_10077402": 2, "Q3T0Y1": 5, "ENSBTAT00000005174": 1, "species_10077404": 3, "reaction_10076001": 4, "species_10075996": 4, "E1B9S7": 4, "ENSBTAT00000021435": 1, "species_10075998": 5, "reaction_10085345": 4, "species_10085342": 4, "reaction_10075952": 3, "species_10075944": 4, "species_10075949": 3, "reaction_10075984": 3, "species_10037956": 2, "species_10075980": 4, "G3N2J6": 3, "ENSBTAT00000064143": 1, "E1BKS3": 3, "ENSBTAT00000020124": 1, "A0A3S5ZPJ2": 3, "ENSBTAT00000016836": 1, "species_10075982": 5, "reaction_10084931": 3, "species_10075838": 4, "species_10084928": 2, "ENSBTAT00000009023": 1, "reaction_10075970": 3, "species_10075966": 4, "P67939": 42, "ENSBTAT00000001420": 2, "species_10075962": 2, "species_10075968": 5, "reaction_10075989": 4, "species_10075986": 3, "reaction_10077371": 3, "species_10077367": 2, "ENSBTAT00000061390": 3, "species_10054896": 2, "ENSBTAT00000044404": 2, "species_10077369": 3, "F1MBM6": 6, "E1BMF7": 3, "reaction_10077339": 3, "species_10077335": 2, "ENSBTAT00000025198": 2, "species_10077337": 4, "F1MUD4": 4, "reaction_10075550": 4, "species_10075418": 4, "A6QLP0": 7, "ENSBTAT00000006418": 3, "species_10075422": 4, "species_10075547": 7, "reaction_10075902": 4, "species_10075897": 2, "A0A3Q1MY85": 3, "ENSBTAT00000087113": 1, "species_10075899": 2, "reaction_10077393": 4, "species_10077388": 5, "A0A3Q1LQ57": 5, "ENSBTAT00000079478": 1, "A0A3Q1MC38": 5, "ENSBTAT00000079399": 1, "A0A3Q1MME1": 5, "ENSBTAT00000043704": 1, "A0A3Q1MAX7": 5, "ENSBTAT00000031172": 1, "species_10075488": 4, "species_10077390": 5, "reaction_10075891": 4, "species_10075886": 5, "F1N3P2": 3, "species_10075888": 5, "reaction_10077363": 4, "species_10077358": 3, "A5PKF9": 3, "ENSBTAT00000022310": 1, "species_10077360": 3, "species_10075884": 6, "reaction_10077331": 4, "species_10077326": 3, "F1MRW5": 6, "ENSBTAT00000077512": 3, "E1BLZ0": 3, "ENSBTAT00000026571": 1, "species_10077328": 3, "reaction_10075561": 4, "species_10075556": 3, "A0A452DHT6": 3, "ENSBTAT00000000967": 1, "species_10075558": 3, "reaction_10077034": 4, "species_10077029": 3, "A0A3Q1MMX0": 3, "ENSBTAT00000075352": 1, "F1MKU1": 7, "ENSBTAT00000061377": 2, "species_10077031": 3, "reaction_10077292": 4, "species_10077171": 3, "F1MSB6": 3, "ENSBTAT00000029564": 1, "species_10077189": 3, "species_10077289": 4, "reaction_10077070": 4, "species_10077061": 6, "E1BJZ0": 3, "ENSBTAT00000010703": 1, "species_10077067": 6, "reaction_10075808": 4, "species_10075801": 8, "A0A3Q1N5C0": 3, "ENSBTAT00000087295": 1, "Q5EAE2": 3, "ENSBTAT00000047754": 1, "P0C8Z3": 3, "ENSBTAT00000011818": 1, "A5PJW1": 3, "ENSBTAT00000000926": 1, "E1BP59": 4, "ENSBTAT00000061193": 1, "E1BKJ5": 3, "ENSBTAT00000009365": 1, "G5E6P9": 3, "ENSBTAT00000013438": 1, "species_10075805": 8, "reaction_10077379": 3, "species_10077375": 3, "A0A3Q1N3E8": 5, "ENSBTAT00000080740": 1, "species_10077373": 2, "species_10077377": 4, "reaction_10077349": 4, "species_10077344": 3, "E1BL26": 3, "ENSBTAT00000045376": 1, "species_10077346": 3, "reaction_10077317": 4, "species_10077308": 4, "A0A3Q1LF69": 3, "ENSBTAT00000074281": 4, "A0A3Q1MAA7": 3, "ENSBTAT00000081720": 1, "species_10077314": 4, "reaction_10075374": 3, "species_10075366": 3, "ENSBTAT00000002506": 2, "species_10075370": 3, "ENSBTAT00000007611": 2, "species_10075372": 3, "A6H799": 4, "Q29RK4": 7, "reaction_10075397": 5, "species_10075394": 5, "A0A3Q1MF75": 2, "ENSBTAT00000067648": 1, "A0A3Q1M4J1": 2, "ENSBTAT00000073722": 1, "F1ME39": 2, "ENSBTAT00000008984": 1, "reaction_10086303": 5, "species_10086293": 2, "ENSBTAT00000061405": 2, "species_10086296": 2, "species_10086300": 2, "ENSBTAT00000084035": 1, "reaction_10086319": 5, "species_10038086": 3, "ENSBTAT00000087016": 4, "species_10086312": 2, "species_10086316": 2, "ENSBTAT00000085737": 1, "reaction_10086286": 5, "species_10086279": 2, "species_10086283": 2, "ENSBTAT00000065836": 1, "reaction_10077744": 5, "species_10037000": 3, "species_10077737": 2, "species_10077741": 2, "ENSBTAT00000046124": 1, "reaction_10083231": 3, "species_10037407": 2, "species_10083225": 5, "Q2HJA9": 3, "ENSBTAT00000043370": 2, "A5PKD6": 4, "ENSBTAT00000083809": 1, "P11017": 4, "ENSBTAT00000008508": 1, "species_10083229": 7, "reaction_10083808": 4, "species_10083806": 7, "species_10083195": 2, "reaction_10077947": 2, "species_10074840": 3, "ENSBTAT00000045134": 6, "species_10074859": 3, "P15781": 6, "reaction_10088922": 2, "species_10088918": 2, "P35246": 8, "ENSBTAT00000008579": 1, "species_10088920": 3, "reaction_10074686": 7, "species_5684863": 3, "species_1602402": 4, "species_5684869": 4, "species_10074683": 2, "ENSBTAT00000019840": 1, "reaction_10074833": 9, "species_10074821": 3, "ENSBTAT00000016672": 8, "species_10074817": 3, "species_5686242": 3, "species_10074827": 3, "species_10074825": 3, "species_10074831": 2, "ENSBTAT00000035930": 1, "reaction_10091120": 2, "species_10075101": 3, "reaction_10074707": 3, "species_10074703": 2, "ENSBTAT00000024905": 2, "species_10074699": 2, "ENSBTAT00000050784": 2, "species_10074705": 3, "A5PJN1": 2, "E1B9V4": 2, "reaction_10074869": 2, "species_10074865": 2, "species_10074867": 3, "reaction_10075125": 6, "species_10075103": 8, "A0A3Q1NJ66": 9, "ENSBTAT00000068360": 1, "A0A452DJB4": 2, "species_10075111": 2, "species_10075123": 2, "species_10075117": 2, "species_10075099": 4, "species_10075115": 2, "reaction_10091124": 2, "species_10091122": 2, "species_10074838": 3, "reaction_10075095": 5, "species_10075088": 2, "species_10075070": 3, "species_10075092": 2, "ENSBTAT00000064000": 1, "reaction_10074857": 6, "species_5685882": 2, "species_10074844": 2, "species_10074842": 2, "species_10074854": 4, "E1BJW6": 2, "ENSBTAT00000008917": 1, "F1N373": 2, "ENSBTAT00000019640": 1, "reaction_10075019": 2, "species_10075015": 2, "species_10075017": 4, "reaction_10075084": 2, "species_10075072": 4, "species_10075082": 3, "reaction_10075023": 5, "species_10075021": 2, "species_10074861": 3, "reaction_10074863": 4, "reaction_10075086": 3, "reaction_10075105": 6, "reaction_10081291": 4, "species_10081288": 5, "G5E5N0": 3, "ENSBTAT00000026157": 4, "A0A3Q1MBQ2": 3, "ENSBTAT00000071531": 2, "A0A3Q1MIB8": 2, "ENSBTAT00000071790": 4, "species_10081284": 5, "species_10043771": 2, "species_10043769": 2, "reaction_10081274": 5, "species_10081269": 2, "species_10081272": 3, "species_10074441": 8, "ENSBTAT00000040104": 2, "reaction_10081293": 3, "species_10043767": 2, "reaction_10081278": 2, "species_10081276": 3, "reaction_10081286": 3, "species_10081282": 2, "reaction_10080457": 5, "species_10053725": 7, "A0A3Q1ML53": 3, "ENSBTAT00000083153": 5, "G3N3R0": 3, "A0A3Q1MWH2": 3, "F1MJ74": 3, "A0A3Q1LXQ4": 3, "F1N3X9": 3, "ENSBTAT00000057355": 1, "species_10080455": 7, "reaction_10081305": 3, "species_10081301": 2, "ENSBTAT00000033862": 2, "species_10052892": 2, "species_10081303": 3, "Q3T013": 2, "reaction_10081323": 3, "species_10081319": 2, "Q32KN9": 3, "ENSBTAT00000006594": 1, "species_10081309": 2, "ENSBTAT00000016994": 2, "species_10081321": 4, "Q0P5E1": 2, "reaction_10081326": 3, "species_1500590": 4, "species_1524101": 3, "reaction_10080738": 2, "species_10080734": 2, "ENSBTAT00000004413": 2, "species_10080736": 3, "Q0VC75": 2, "reaction_10080789": 6, "species_6799725": 1, "species_6799726": 1, "reaction_10056702": 7, "species_29406": 16, "species_10056667": 2, "ENSBTAT00000075132": 3, "species_29434": 2, "species_10056691": 2, "species_10056699": 4, "F1MG82": 2, "ENSBTAT00000000101": 1, "reaction_10056679": 2, "species_10056671": 3, "A0A3Q1MIU5": 10, "A0A3Q1MKG5": 10, "ENSBTAT00000077844": 5, "species_10056677": 3, "reaction_10056761": 3, "species_10056629": 3, "species_10056659": 11, "A7MBA0": 5, "ENSBTAT00000010744": 1, "A0A3Q1M2B6": 4, "ENSBTAT00000066920": 1, "G5E5X0": 4, "ENSBTAT00000037007": 1, "species_10056685": 13, "reaction_10056719": 7, "species_10056675": 2, "species_113671": 18, "species_113685": 16, "species_10056704": 2, "species_159942": 17, "species_159939": 18, "species_10056716": 5, "A0A3Q1LUX2": 2, "ENSBTAT00000072600": 1, "reaction_10056737": 3, "species_10056723": 3, "species_10056733": 5, "species_10056735": 8, "reaction_10056688": 4, "species_10056683": 7, "species_10056661": 15, "species_10056681": 4, "reaction_10056754": 4, "species_10056747": 7, "species_10056751": 11, "species_10056745": 4, "reaction_10056757": 7, "species_10056669": 2, "species_10056627": 2, "reaction_10056759": 2, "species_10056633": 10, "reaction_10044776": 3, "species_10044772": 3, "F1N021": 4, "ENSBTAT00000044965": 1, "A0A3Q1LX71": 4, "ENSBTAT00000079466": 1, "species_10033775": 4, "ENSBTAT00000005575": 2, "species_10044774": 5, "P27117": 4, "reaction_10044794": 3, "species_10044788": 2, "ENSBTAT00000072826": 2, "species_10044792": 5, "A3KMV9": 2, "reaction_10044784": 3, "species_10044780": 2, "ENSBTAT00000079752": 2, "species_10044782": 3, "A0A3Q1MK02": 2, "reaction_10047519": 5, "species_10047512": 4, "A0A3Q1MI55": 2, "ENSBTAT00000066483": 1, "A0A3Q1MTG9": 4, "ENSBTAT00000077316": 1, "A0A3Q1LME0": 3, "ENSBTAT00000075439": 3, "species_10047517": 5, "reaction_10047536": 3, "species_10047534": 4, "reaction_10052466": 4, "species_10047510": 3, "species_10047515": 3, "species_10052464": 3, "reaction_10052471": 5, "species_427893": 2, "ENSBTAT00000030539": 1, "reaction_10071800": 3, "species_29804": 34, "species_74126": 28, "species_10071797": 5, "Q2KHV0": 3, "ENSBTAT00000001530": 1, "Q2NKS7": 3, "ENSBTAT00000037245": 1, "A0A3Q1MT75": 3, "ENSBTAT00000087044": 1, "A0A3Q1LPA7": 2, "ENSBTAT00000069177": 1, "reaction_10059961": 5, "species_1605590": 1, "species_1605647": 1, "reaction_10071483": 3, "species_1638840": 2, "species_5339515": 1, "species_10071480": 2, "ENSBTAT00000010025": 1, "reaction_10084410": 5, "species_8856243": 3, "species_1605641": 3, "CHEBI:28424": 1, "species_8856242": 3, "species_1605610": 3, "CHEBI:28648": 1, "species_10084407": 2, "Q58DI2": 2, "ENSBTAT00000005893": 1, "reaction_10060316": 5, "species_429776": 4, "species_429807": 6, "species_1610735": 2, "species_10060313": 2, "ENSBTAT00000002552": 1, "reaction_10059984": 5, "species_1605649": 1, "species_1605618": 1, "reaction_10059954": 3, "species_10059927": 3, "ENSBTAT00000029099": 2, "species_10059929": 4, "E1BI28": 4, "reaction_10060021": 5, "species_1606609": 1, "species_1861754": 1, "species_10060018": 1, "reaction_10060309": 5, "species_10060306": 2, "ENSBTAT00000064397": 1, "reaction_10059991": 5, "species_1605713": 1, "species_1605750": 1, "species_1605673": 1, "species_10059988": 2, "ENSBTAT00000020758": 1, "reaction_10059977": 5, "species_1605716": 2, "species_1605637": 1, "species_1605601": 2, "species_10059974": 2, "E1B725": 4, "ENSBTAT00000025636": 1, "reaction_10060041": 5, "species_1609648": 1, "species_1609650": 1, "species_1609649": 1, "species_10060038": 3, "reaction_10071497": 3, "species_5340315": 1, "species_5340299": 1, "species_10071494": 2, "ENSBTAT00000003355": 1, "reaction_10059944": 6, "reaction_10060012": 5, "species_10060009": 3, "F1N588": 2, "ENSBTAT00000010706": 1, "reaction_10059951": 5, "species_1605608": 1, "species_10059948": 3, "reaction_10060302": 5, "species_744227": 1, "species_428270": 5, "species_1660674": 1, "species_10060299": 2, "ENSBTAT00000043826": 1, "reaction_10059968": 5, "species_10059965": 2, "ENSBTAT00000019755": 1, "reaction_10048986": 4, "species_428203": 5, "species_428671": 2, "species_428686": 5, "species_10048983": 3, "ENSBTAT00000080801": 1, "reaction_10049116": 4, "species_10049108": 6, "A2VDZ9": 5, "ENSBTAT00000023164": 1, "A0A452DJG0": 5, "ENSBTAT00000053250": 1, "species_428256": 7, "Q9GKI7": 4, "ENSBTAT00000056797": 4, "species_10049110": 7, "species_10049114": 3, "ENSBTAT00000027095": 1, "reaction_10048860": 7, "species_200736": 9, "species_9695889": 1, "species_428182": 1, "species_10048843": 5, "Q5E978": 2, "ENSBTAT00000018578": 1, "Q0IIK4": 2, "ENSBTAT00000085219": 1, "Q3MHG1": 2, "ENSBTAT00000002872": 1, "A5PKM3": 2, "ENSBTAT00000027289": 1, "species_10048858": 4, "Q0VD15": 6, "ENSBTAT00000018402": 1, "Q29RQ9": 2, "ENSBTAT00000016673": 1, "Q5E972": 2, "ENSBTAT00000027540": 1, "reaction_10048988": 4, "species_428275": 3, "species_428663": 2, "reaction_10049182": 9, "species_429802": 6, "species_10049179": 2, "ENSBTAT00000072919": 1, "reaction_10048978": 5, "species_428694": 1, "species_10048975": 4, "A0JNA1": 2, "ENSBTAT00000005808": 1, "A0A3Q1N0W7": 2, "ENSBTAT00000067390": 1, "reaction_10048917": 5, "species_9025544": 2, "species_428237": 1, "species_3632878": 1, "species_10048914": 2, "ENSBTAT00000052101": 1, "reaction_10049161": 4, "species_10049158": 5, "reaction_10049163": 3, "species_10049100": 4, "species_10049147": 3, "reaction_10082058": 7, "species_6808468": 1, "species_2453691": 1, "species_10082055": 3, "A0A3Q1M3Q4": 2, "ENSBTAT00000085198": 1, "Q1JPA0": 6, "ENSBTAT00000076578": 2, "reaction_10048910": 8, "species_428126": 2, "species_10048907": 2, "ENSBTAT00000012243": 1, "reaction_10048896": 5, "species_428163": 2, "species_10048893": 3, "ENSBTAT00000074462": 2, "reaction_10049154": 5, "species_10049124": 3, "species_10049151": 2, "ENSBTAT00000022345": 1, "reaction_10048903": 9, "species_428193": 3, "species_428198": 2, "species_10048900": 2, "ENSBTAT00000010648": 1, "reaction_10048889": 5, "species_428248": 1, "species_10048886": 2, "ENSBTAT00000014354": 1, "reaction_10048882": 5, "species_10048879": 5, "A0A3Q1MVP2": 2, "ENSBTAT00000082150": 1, "A0A3Q1MJ30": 2, "ENSBTAT00000080491": 1, "A4FUG2": 2, "ENSBTAT00000036524": 1, "A5D7K4": 2, "ENSBTAT00000052579": 1, "reaction_10049141": 5, "species_10049119": 3, "species_10049138": 4, "A0A3Q1N9F5": 2, "ENSBTAT00000081006": 1, "F1MIA2": 2, "ENSBTAT00000020721": 1, "E1B7L9": 2, "ENSBTAT00000070039": 1, "reaction_10049143": 3, "reaction_10076151": 7, "species_10076148": 2, "reaction_10049004": 5, "species_428682": 2, "species_10049001": 3, "A0A3Q1MIK4": 2, "ENSBTAT00000069794": 2, "Q3SZE3": 2, "ENSBTAT00000015460": 1, "reaction_10049007": 5, "reaction_10049121": 3, "reaction_10076833": 7, "species_10076830": 2, "reaction_10091936": 3, "species_10091933": 2, "ENSBTAT00000009765": 1, "reaction_10048995": 5, "species_428662": 1, "species_10048992": 2, "reaction_10076389": 5, "species_5693768": 1, "species_10076386": 2, "ENSBTAT00000016212": 1, "reaction_10049189": 9, "species_429773": 2, "species_429789": 2, "species_10049186": 2, "ENSBTAT00000082007": 1, "reaction_10091941": 6, "species_10091939": 2, "A0A3Q1MBG6": 2, "reaction_10043933": 6, "species_29506": 1, "species_209849": 1, "species_71112": 3, "species_10043930": 3, "A0A3Q1MAN0": 2, "ENSBTAT00000077835": 1, "reaction_10073477": 3, "species_5662665": 1, "species_5662670": 1, "species_10073474": 3, "F1MC37": 2, "ENSBTAT00000034881": 1, "reaction_10044216": 8, "species_215075": 1, "species_10044213": 2, "Q148E6": 2, "ENSBTAT00000015892": 1, "reaction_10044195": 8, "species_352318": 1, "species_10044192": 5, "reaction_10044260": 8, "species_215062": 5, "species_10044257": 3, "reaction_10035958": 8, "species_42373": 1, "species_10035955": 2, "reaction_10048504": 6, "species_10048501": 3, "E1B7D0": 2, "ENSBTAT00000014410": 1, "A0A3Q1LST7": 2, "ENSBTAT00000077819": 1, "reaction_10072522": 7, "species_5626313": 1, "species_167012": 2, "species_425958": 1, "species_10072519": 2, "ENSBTAT00000006382": 1, "reaction_10048526": 7, "species_10048523": 5, "F1MD60": 2, "ENSBTAT00000008703": 1, "A0A3Q1M073": 2, "ENSBTAT00000074844": 1, "E1BM98": 2, "ENSBTAT00000061324": 1, "E1BGG7": 2, "ENSBTAT00000015768": 1, "reaction_10048533": 5, "species_425815": 1, "species_425810": 1, "species_10048530": 2, "ENSBTAT00000070502": 2, "reaction_10038895": 8, "species_73663": 1, "species_76633": 1, "species_10038882": 46, "P23934": 4, "ENSBTAT00000013078": 1, "P04394": 4, "ENSBTAT00000006405": 1, "A0A3Q1M7B1": 4, "ENSBTAT00000065530": 2, "A0A3Q1N0E1": 4, "P15690": 4, "ENSBTAT00000029301": 1, "A0A452DIK0": 4, "ENSBTAT00000019529": 1, "A0A3Q1MG52": 4, "ENSBTAT00000075840": 1, "Q02379": 3, "ENSBTAT00000077219": 2, "Q85BD6": 4, "ENSBTAT00000060577": 2, "Q6QTH1": 6, "ENSBTAT00000060571": 1, "P42026": 6, "ENSBTAT00000053067": 1, "P34943": 6, "ENSBTAT00000007189": 1, "Q02374": 6, "ENSBTAT00000029003": 1, "A0A3Q1LFL6": 6, "ENSBTAT00000035646": 1, "A0A3Q1MFA0": 6, "ENSBTAT00000071194": 2, "A0A3Q1M144": 6, "Q02377": 6, "ENSBTAT00000007925": 1, "Q02365": 6, "ENSBTAT00000016957": 1, "Q02827": 8, "ENSBTAT00000024209": 1, "P23935": 6, "ENSBTAT00000012287": 1, "A0A3Q1LW79": 6, "ENSBTAT00000067852": 1, "P42029": 6, "ENSBTAT00000005628": 1, "Q02369": 6, "ENSBTAT00000027191": 1, "Q02373": 6, "ENSBTAT00000012542": 1, "A0A452DIB4": 6, "ENSBTAT00000012512": 1, "Q02368": 6, "ENSBTAT00000016768": 1, "Q8HXG5": 6, "ENSBTAT00000070642": 1, "Q05752": 6, "ENSBTAT00000077911": 1, "Q02370": 6, "ENSBTAT00000020018": 1, "A0A3Q1LID6": 6, "ENSBTAT00000072963": 1, "Q95KV7": 6, "ENSBTAT00000010276": 1, "Q02371": 6, "ENSBTAT00000010193": 1, "Q02380": 6, "ENSBTAT00000003197": 1, "Q8HXG6": 6, "ENSBTAT00000025322": 1, "A0A3Q1MBM6": 7, "ENSBTAT00000084872": 1, "Q6QTH0": 7, "ENSBTAT00000060548": 1, "P03924": 6, "ENSBTAT00000060562": 2, "Q02367": 6, "ENSBTAT00000007761": 2, "P03898": 7, "ENSBTAT00000060547": 1, "Q5EA03": 7, "ENSBTAT00000030501": 1, "P03910": 4, "ENSBTAT00000060552": 2, "species_10038893": 3, "F1MK72": 2, "ENSBTAT00000006115": 1, "Q1RMM6": 2, "ENSBTAT00000005722": 1, "reaction_10080521": 3, "species_10080503": 12, "A0A3Q1MP25": 6, "ENSBTAT00000085097": 1, "Q3SX05": 6, "E1BAZ2": 6, "ENSBTAT00000074751": 1, "E1BCS4": 6, "ENSBTAT00000027441": 1, "species_10080485": 32, "Q2HJI2": 5, "ENSBTAT00000025174": 1, "A4FUH5": 5, "ENSBTAT00000004122": 1, "A7YVD7": 5, "ENSBTAT00000009959": 1, "species_10080505": 43, "reaction_10080515": 4, "species_10038704": 2, "species_10080511": 9, "species_10080507": 45, "species_10080513": 53, "reaction_10080517": 4, "species_10038708": 2, "species_10038712": 2, "reaction_10080519": 6, "species_10038740": 3, "species_10080501": 5, "species_10038720": 2, "species_10038716": 2, "species_10038730": 3, "reaction_10038647": 11, "species_10038546": 4, "CHEBI:38573": 1, "P62894": 3, "ENSBTAT00000007918": 4, "species_10038548": 4, "CHEBI:38574": 1, "species_10038606": 16, "E1BH77": 3, "ENSBTAT00000006474": 1, "P68530": 3, "ENSBTAT00000060549": 1, "A0A3Q1LKB8": 3, "ENSBTAT00000080485": 1, "Q6QTG5": 3, "ENSBTAT00000060566": 1, "A0A3Q1MBD7": 3, "ENSBTAT00000076309": 1, "Q6QTG9": 3, "ENSBTAT00000060569": 1, "A0A3Q1MB49": 3, "ENSBTAT00000067651": 1, "CHEBI:28694": 4, "Q01321": 3, "ENSBTAT00000014801": 1, "P00426": 3, "ENSBTAT00000022949": 1, "P00430": 3, "ENSBTAT00000079150": 1, "P00423": 3, "ENSBTAT00000053881": 1, "P13182": 3, "ENSBTAT00000071537": 1, "Q3T061": 3, "ENSBTAT00000000943": 1, "species_10038643": 5, "A6H784": 2, "ENSBTAT00000016742": 1, "A0A3Q1MQS6": 2, "ENSBTAT00000067855": 1, "E1BJK7": 2, "ENSBTAT00000013031": 1, "E1BPX9": 2, "ENSBTAT00000021773": 1, "species_10038611": 2, "ENSBTAT00000020289": 1, "species_10038625": 4, "A0A3Q1MMW4": 2, "ENSBTAT00000082257": 1, "F1N5P2": 2, "ENSBTAT00000007094": 1, "Q1RMH3": 2, "ENSBTAT00000001069": 1, "species_10038645": 17, "species_9709335": 3, "reaction_10084313": 2, "species_10084133": 11, "species_10074027": 11, "reaction_10084185": 4, "species_10084177": 13, "species_10084183": 13, "reaction_10084153": 3, "species_10074025": 17, "species_10084151": 10, "reaction_10085755": 3, "species_10074005": 3, "species_10084137": 4, "species_10084157": 5, "reaction_10084187": 3, "species_10073999": 3, "species_10084159": 6, "reaction_10084379": 3, "species_10084375": 3, "species_10084377": 11, "reaction_10085757": 3, "species_10074017": 2, "species_10084161": 4, "reaction_10084190": 4, "species_10084167": 10, "reaction_10084309": 3, "species_10084175": 12, "reaction_10084149": 3, "species_10084145": 3, "ENSBTAT00000081071": 2, "species_10084147": 10, "A0A3Q1LNN8": 6, "reaction_10084311": 3, "species_10074031": 11, "reaction_10084169": 2, "species_10084165": 9, "reaction_10084393": 3, "species_10084389": 5, "Q3SX40": 3, "ENSBTAT00000009662": 1, "species_10084391": 13, "reaction_10084330": 3, "species_10084328": 10, "reaction_10084141": 3, "species_10073976": 2, "species_10084139": 4, "reaction_10084352": 3, "species_10084348": 5, "G3N3X9": 3, "ENSBTAT00000064953": 1, "A7MBB8": 3, "ENSBTAT00000004337": 1, "A4IFJ7": 3, "ENSBTAT00000071968": 1, "Q0VCR5": 3, "ENSBTAT00000064819": 1, "species_10084350": 13, "reaction_10084131": 3, "species_10074029": 12, "reaction_10084194": 3, "species_10084192": 10, "reaction_10084196": 3, "species_10073972": 2, "species_10084155": 4, "reaction_10084135": 3, "reaction_10084198": 3, "species_10074013": 2, "species_10084163": 4, "reaction_10084326": 3, "species_10084324": 13, "reaction_10061049": 5, "species_2023891": 2, "species_2023901": 5, "species_10061028": 5, "ENSBTAT00000014872": 1, "reaction_10061017": 5, "species_2023922": 2, "species_10060948": 7, "Q0II95": 2, "ENSBTAT00000015405": 2, "F6Q4Q6": 2, "ENSBTAT00000030644": 1, "reaction_10061128": 5, "species_2023892": 1, "reaction_10061131": 5, "species_2023948": 1, "reaction_10061052": 5, "species_2023929": 2, "species_2023940": 2, "reaction_10061119": 5, "species_2023941": 1, "reaction_10061137": 5, "species_2023907": 1, "reaction_10060993": 5, "species_10060990": 2, "ENSBTAT00000015737": 2, "reaction_10061031": 5, "species_2023935": 1, "reaction_10060951": 5, "species_2023932": 1, "species_2023931": 1, "reaction_10067955": 4, "species_10067950": 7, "F1N6Q0": 5, "ENSBTAT00000021199": 1, "Q5E954": 5, "ENSBTAT00000021637": 1, "Q2HJ94": 5, "ENSBTAT00000004890": 1, "Q27975": 11, "ENSBTAT00000017500": 1, "species_10067952": 6, "species_10067948": 4, "reaction_10068022": 3, "species_10068020": 3, "species_10068018": 4, "reaction_10065708": 2, "species_10065697": 3, "ENSBTAT00000011761": 2, "species_10065705": 2, "F1MW01": 3, "reaction_10065726": 3, "species_10065722": 4, "G3N089": 3, "ENSBTAT00000066220": 3, "A0A452DIH5": 3, "G3MYU8": 3, "species_10065724": 5, "reaction_10091145": 3, "species_9624879": 1, "species_10091134": 5, "G3MZP2": 6, "ENSBTAT00000033457": 2, "G5E619": 6, "species_10091143": 4, "reaction_10091141": 5, "species_10043519": 4, "species_10091138": 2, "ENSBTAT00000066656": 1, "reaction_10091132": 3, "species_10044128": 3, "ENSBTAT00000008650": 2, "species_10091128": 2, "ENSBTAT00000011125": 3, "species_10091130": 3, "A6QQV8": 2, "E1BFV0": 12, "reaction_10091656": 3, "species_10091652": 2, "ENSBTAT00000065503": 2, "species_10091648": 12, "F1N7R5": 4, "ENSBTAT00000021129": 2, "E1B828": 6, "ENSBTAT00000020642": 2, "species_10091654": 12, "G3X8E2": 2, "reaction_10091658": 3, "species_10091644": 10, "species_10091640": 2, "species_10091646": 11, "reaction_10091661": 7, "species_10040834": 3, "reaction_10091634": 3, "species_10052771": 2, "species_10070769": 2, "species_10091632": 3, "reaction_10091663": 4, "species_10039904": 2, "ENSBTAT00000020389": 2, "species_10039900": 2, "ENSBTAT00000002226": 2, "species_10039896": 2, "ENSBTAT00000026311": 2, "species_10039906": 4, "E1B8Q4": 2, "P0CG11": 2, "F1MTU0": 2, "reaction_10057418": 3, "species_10057415": 4, "O19182": 2, "ENSBTAT00000010914": 1, "A0A3Q1M4V6": 2, "ENSBTAT00000078632": 1, "E1BCI4": 2, "ENSBTAT00000000089": 1, "reaction_10064591": 5, "species_2162214": 1, "species_2162213": 1, "species_2162207": 1, "species_10064588": 2, "ENSBTAT00000007549": 1, "reaction_10046968": 7, "species_389545": 1, "species_10046965": 2, "A0A140T8A5": 8, "ENSBTAT00000027348": 1, "reaction_10058524": 4, "species_1474124": 2, "species_1475054": 1, "species_1474179": 1, "species_10058521": 4, "A0A3Q1MA59": 3, "ENSBTAT00000030411": 1, "reaction_10058511": 8, "species_10058500": 3, "F1MZ14": 3, "ENSBTAT00000009020": 1, "species_29502": 4, "species_10058509": 4, "Q32L41": 3, "ENSBTAT00000017922": 1, "reaction_10058785": 5, "species_10058778": 2, "species_10058782": 2, "ENSBTAT00000003877": 1, "reaction_10058514": 3, "species_10058507": 2, "reaction_10085853": 2, "species_10085849": 4, "species_8874708": 3, "F1N086": 3, "ENSBTAT00000030426": 2, "species_10085851": 3, "reaction_10085855": 3, "species_10085847": 2, "reaction_10081928": 4, "species_6806366": 2, "species_6806362": 3, "species_10081925": 2, "ENSBTAT00000064807": 1, "reaction_10038427": 5, "species_10038422": 3, "Q6B4J2": 3, "ENSBTAT00000000519": 1, "species_10038425": 3, "reaction_10090493": 3, "species_9035082": 1, "reaction_10081935": 5, "species_6806891": 1, "species_6806657": 1, "species_6806656": 1, "species_10081932": 2, "ENSBTAT00000018617": 1, "reaction_10054393": 6, "species_10054390": 5, "A7MBG1": 3, "ENSBTAT00000078995": 2, "species_10054388": 5, "species_975590": 10, "species_10035574": 2, "reaction_10066249": 3, "species_2473610": 1, "species_10035554": 6, "A0A3Q1LU75": 5, "ENSBTAT00000012885": 1, "A0A452DJ95": 5, "ENSBTAT00000015936": 1, "species_10065443": 5, "reaction_10054395": 3, "species_10054386": 3, "reaction_10070971": 3, "species_10070967": 2, "ENSBTAT00000075540": 2, "species_5246487": 4, "species_10070969": 5, "A0A3Q1MB70": 2, "reaction_10065437": 3, "reaction_10069948": 5, "species_5164389": 1, "species_5164390": 1, "species_5164383": 1, "species_10069945": 3, "F1N2Z9": 2, "ENSBTAT00000048395": 1, "reaction_10054382": 5, "species_975591": 2, "species_10054379": 3, "ENSBTAT00000076923": 1, "reaction_10065441": 3, "species_2473616": 2, "species_10065439": 4, "reaction_10065445": 3, "reaction_10054404": 4, "species_975643": 1, "species_10054401": 3, "F1N3B7": 2, "ENSBTAT00000048748": 1, "reaction_10054375": 5, "species_10041236": 5, "A0JNQ7": 2, "ENSBTAT00000022391": 1, "E1BJQ9": 2, "ENSBTAT00000001012": 1, "reaction_10066247": 6, "species_10066244": 15, "F1N678": 2, "reaction_10042657": 5, "species_199238": 1, "species_199207": 4, "species_10042645": 5, "Q32LE7": 2, "ENSBTAT00000017091": 1, "F1MN65": 2, "ENSBTAT00000032961": 1, "reaction_10066401": 7, "species_10066388": 3, "species_10066394": 4, "species_10066398": 2, "ENSBTAT00000057284": 1, "reaction_10067733": 2, "reaction_10042936": 3, "species_111355": 5, "species_10042933": 2, "ENSBTAT00000048106": 1, "reaction_10081339": 5, "species_6801458": 2, "species_10081336": 4, "A0A452DI11": 2, "ENSBTAT00000006419": 1, "E1BNJ2": 2, "ENSBTAT00000061329": 1, "reaction_10042940": 3, "species_200716": 3, "species_197965": 6, "species_10042919": 4, "ENSBTAT00000035283": 1, "reaction_10082078": 8, "species_111353": 1, "species_197969": 1, "species_10082075": 2, "E1BMG9": 2, "ENSBTAT00000043693": 1, "reaction_10042929": 3, "species_200709": 1, "species_200665": 1, "species_10042926": 2, "ENSBTAT00000082124": 1, "reaction_10041840": 6, "species_73604": 4, "species_10041835": 3, "ENSBTAT00000010103": 2, "reaction_10087442": 3, "species_10086761": 4, "Q0VCN9": 6, "ENSBTAT00000027602": 2, "species_10086759": 3, "reaction_10092306": 6, "species_10092303": 2, "A0A140T872": 2, "reaction_10082068": 8, "species_6808499": 1, "species_200679": 1, "species_10082065": 2, "E1BDG9": 2, "ENSBTAT00000008298": 1, "reaction_10086763": 3, "reaction_10042922": 3, "reaction_10041838": 6, "reaction_10081346": 7, "species_6803257": 1, "species_200640": 1, "species_10081343": 2, "ENSBTAT00000026669": 1, "reaction_10076485": 6, "species_10076482": 2, "Q3SZ20": 2, "ENSBTAT00000038244": 1, "reaction_10081349": 4, "species_5389850": 1, "reaction_10041817": 5, "species_10041814": 3, "A0A3Q1NKT9": 2, "ENSBTAT00000069099": 1, "reaction_10042906": 5, "species_8938083": 1, "species_8938078": 1, "species_8938090": 1, "species_10042903": 3, "A0A3Q1NCV5": 2, "ENSBTAT00000074137": 1, "reaction_10088666": 6, "species_10088663": 2, "A0A3Q1LR42": 2, "ENSBTAT00000077253": 1, "reaction_10086748": 5, "species_352330": 4, "species_8940067": 2, "species_10036204": 6, "A0A3Q1MCG3": 2, "ENSBTAT00000074100": 1, "reaction_10086750": 5, "species_8940077": 1, "reaction_10085374": 6, "species_8870342": 3, "species_8870343": 2, "species_10085371": 2, "F1MLP3": 4, "ENSBTAT00000008097": 1, "reaction_10085362": 6, "species_8869377": 2, "species_8869353": 2, "species_10085356": 3, "ENSBTAT00000044763": 1, "reaction_10085365": 6, "species_10085349": 3, "ENSBTAT00000072443": 1, "reaction_10081977": 3, "species_6807473": 1, "species_6807477": 2, "species_10081974": 2, "A0A3Q1MF13": 2, "ENSBTAT00000080451": 1, "reaction_10071643": 5, "species_10039927": 3, "ENSBTAT00000040069": 1, "reaction_10086623": 5, "species_8938276": 1, "species_8938282": 1, "species_10086620": 4, "F6R6Y8": 2, "ENSBTAT00000029045": 1, "A0A3Q1M0E5": 2, "ENSBTAT00000084343": 1, "F1MRP9": 2, "ENSBTAT00000012765": 1, "reaction_10082143": 6, "species_6809289": 1, "species_10082140": 2, "ENSBTAT00000039965": 1, "reaction_10041824": 5, "species_197220": 5, "species_10041821": 2, "ENSBTAT00000083136": 1, "reaction_10041808": 7, "species_10041805": 2, "A0A3Q1N5S3": 4, "ENSBTAT00000084634": 1, "reaction_10081984": 7, "species_10081981": 2, "ENSBTAT00000015238": 1, "reaction_10088867": 6, "species_8956473": 3, "CHEBI:90174": 1, "CHEBI:90171": 1, "species_351629": 14, "species_10088864": 3, "A0A3Q1NF84": 2, "ENSBTAT00000069540": 1, "reaction_10049170": 5, "species_429739": 7, "CHEBI:32544": 2, "species_429748": 7, "species_10049167": 3, "ENSBTAT00000015315": 1, "reaction_10085352": 6, "species_8869365": 2, "reaction_10085359": 6, "reaction_10042915": 5, "species_200492": 1, "species_8878981": 1, "species_200499": 1, "species_10042912": 3, "Q0VD50": 2, "ENSBTAT00000082151": 1, "reaction_10041831": 7, "species_197238": 1, "species_10041828": 2, "ENSBTAT00000083204": 1, "reaction_10086630": 6, "species_10086627": 2, "ENSBTAT00000073897": 1, "reaction_10053298": 8, "species_947561": 1, "species_947496": 1, "species_947539": 3, "species_10053295": 3, "A0A3Q1ME13": 2, "ENSBTAT00000081310": 1, "reaction_10053266": 5, "species_947575": 1, "species_29432": 8, "species_10053263": 2, "ENSBTAT00000065375": 1, "reaction_10053287": 5, "species_10053272": 3, "A1A4L8": 3, "ENSBTAT00000070167": 1, "species_10053277": 3, "species_10053284": 2, "A5PKG4": 5, "ENSBTAT00000009149": 1, "reaction_10053352": 5, "species_965131": 2, "species_29390": 3, "species_10053345": 5, "Q0II59": 6, "ENSBTAT00000024203": 1, "reaction_10066619": 6, "species_3204324": 1, "species_10066616": 5, "CHEBI:33722": 1, "CHEBI:44074": 1, "A0A3Q1LJG6": 2, "ENSBTAT00000075745": 1, "reaction_10053361": 5, "species_964952": 2, "species_10053358": 4, "Q5E9K3": 2, "ENSBTAT00000016263": 1, "reaction_10053363": 7, "species_965146": 2, "reaction_10053348": 5, "species_964945": 1, "reaction_10053350": 5, "species_965053": 1, "reaction_10041753": 5, "species_196934": 2, "species_29480": 2, "species_10041750": 3, "A0A3Q1LMH4": 2, "ENSBTAT00000085465": 1, "reaction_10042799": 3, "species_199622": 1, "species_10042796": 3, "A7E352": 2, "ENSBTAT00000084175": 1, "E1BLU2": 2, "ENSBTAT00000027006": 1, "reaction_10066585": 5, "species_3159260": 1, "species_3159274": 1, "species_10066582": 2, "A0A3Q1NBS4": 2, "ENSBTAT00000056628": 1, "reaction_10066587": 3, "species_10033882": 3, "reaction_10066458": 3, "species_10066454": 2, "ENSBTAT00000015993": 2, "species_3000125": 4, "species_10066456": 3, "species_3000241": 10, "E1BCN2": 4, "reaction_10066461": 3, "species_10066428": 4, "Q9XSC9": 5, "ENSBTAT00000029446": 2, "species_10066440": 3, "ENSBTAT00000005777": 2, "species_10066438": 5, "A6QNY1": 2, "reaction_10076254": 5, "species_10076243": 2, "species_10076247": 2, "species_10076245": 2, "species_10076251": 2, "ENSBTAT00000071882": 1, "reaction_10066526": 3, "species_10066519": 5, "E1BCU6": 6, "ENSBTAT00000027423": 2, "species_10066523": 5, "reaction_10066430": 3, "species_10066426": 2, "reaction_10066576": 3, "species_10066565": 6, "A0A3Q1M6Z9": 3, "ENSBTAT00000087246": 2, "species_3149479": 3, "Q5E9C8": 4, "ENSBTAT00000022638": 2, "species_10066567": 4, "species_3149564": 1, "reaction_10066450": 2, "species_10066442": 4, "species_10066448": 4, "reaction_10066569": 3, "reaction_10066473": 2, "species_3000239": 1, "reaction_10066571": 3, "species_10066563": 2, "species_10066499": 5, "reaction_10066444": 3, "reaction_10066574": 7, "species_10066497": 3, "species_3149505": 1, "species_1130611": 1, "reaction_10066528": 4, "species_10066517": 3, "species_3132775": 2, "species_3132772": 1, "reaction_10066882": 3, "reaction_10066471": 2, "species_10066469": 3, "species_10066465": 3, "reaction_10066502": 6, "reaction_10042648": 5, "species_199192": 1, "species_196820": 3, "reaction_10041737": 7, "species_196786": 1, "species_196834": 2, "species_10041734": 2, "A0A3S5ZP75": 2, "ENSBTAT00000017259": 1, "reaction_10041756": 5, "species_196778": 2, "species_10041741": 3, "ENSBTAT00000072656": 1, "reaction_10042655": 3, "species_10042652": 2, "ENSBTAT00000031344": 1, "reaction_10041744": 5, "species_196767": 2, "reaction_10041765": 4, "species_10041762": 3, "A0A3Q1MNK4": 2, "ENSBTAT00000076608": 1, "reaction_10053048": 2, "species_10039550": 2, "ENSBTAT00000075628": 2, "species_10039554": 6, "A0A3Q1MWF9": 10, "reaction_10053046": 2, "species_10040193": 5, "reaction_10037203": 5, "species_10037126": 4, "A6QQS5": 3, "ENSBTAT00000023832": 1, "G5E5S2": 3, "ENSBTAT00000029144": 1, "F1MW69": 3, "ENSBTAT00000025006": 1, "species_10037171": 17, "A0A3Q1N7E3": 4, "ENSBTAT00000071171": 2, "A0A3Q1MQ76": 4, "ENSBTAT00000070366": 2, "E1BMM0": 15, "ENSBTAT00000061170": 2, "Q3ZBJ1": 15, "ENSBTAT00000011684": 2, "Q1JQ91": 4, "ENSBTAT00000074897": 1, "Q5E9B8": 4, "ENSBTAT00000012481": 1, "Q5EA53": 4, "ENSBTAT00000027988": 1, "Q2T9L9": 4, "ENSBTAT00000078070": 1, "Q32P79": 4, "ENSBTAT00000007165": 1, "G3MZY8": 4, "ENSBTAT00000069267": 1, "Q3T0Q3": 4, "ENSBTAT00000002420": 1, "A0A3Q1MWS0": 4, "ENSBTAT00000080412": 1, "species_30595": 6, "species_10037173": 21, "reaction_10037205": 3, "species_10037169": 14, "species_10037137": 4, "reaction_10086136": 6, "species_10086105": 8, "A0A3Q1MNB1": 14, "ENSBTAT00000080327": 2, "A0A3Q1MPF1": 14, "F1N2I0": 10, "ENSBTAT00000014310": 1, "P21856": 10, "ENSBTAT00000016093": 1, "F1MS24": 10, "ENSBTAT00000012631": 1, "species_10086115": 3, "species_10085883": 13, "species_10086133": 12, "A0A3Q1N5L8": 2, "ENSBTAT00000086931": 1, "A0A3Q1MK52": 2, "ENSBTAT00000082010": 1, "F1MXL8": 2, "ENSBTAT00000009769": 1, "reaction_10085932": 6, "species_10085911": 8, "A6QLS9": 5, "ENSBTAT00000001303": 1, "species_10085915": 3, "species_10085929": 4, "E1BJE1": 2, "ENSBTAT00000022733": 1, "F1N377": 2, "ENSBTAT00000034026": 1, "A0A3Q1NBE4": 2, "ENSBTAT00000073212": 1, "reaction_10086097": 6, "species_10086086": 8, "Q08DC2": 5, "ENSBTAT00000075871": 1, "species_10086090": 3, "species_10086094": 2, "ENSBTAT00000013748": 1, "reaction_10086209": 6, "species_10086188": 8, "G3X7D3": 5, "ENSBTAT00000024288": 1, "species_10086196": 3, "species_10086206": 3, "A0A3Q1MUN3": 2, "ENSBTAT00000069720": 1, "F1MQ87": 2, "ENSBTAT00000027075": 1, "reaction_10086019": 6, "species_10086008": 8, "Q3ZBG1": 5, "ENSBTAT00000023671": 1, "species_10086012": 3, "species_10086016": 2, "ENSBTAT00000067401": 1, "reaction_10085988": 6, "species_10085979": 8, "A6QPX8": 3, "ENSBTAT00000013671": 1, "species_10085983": 3, "species_10085985": 2, "A0A3Q1MCL3": 2, "ENSBTAT00000087265": 1, "reaction_10086054": 6, "species_10086037": 8, "F1MPP1": 3, "ENSBTAT00000025807": 1, "species_10086041": 3, "species_10086051": 3, "A0A3Q1M4Y7": 2, "ENSBTAT00000075635": 1, "A0A3Q1M373": 2, "ENSBTAT00000078087": 1, "reaction_10086182": 6, "species_10086161": 9, "E1BA60": 3, "ENSBTAT00000012905": 1, "E1B9C0": 3, "ENSBTAT00000020971": 1, "species_10086169": 4, "species_10086179": 3, "E1B7M9": 2, "ENSBTAT00000056415": 1, "A0A3Q1N720": 2, "ENSBTAT00000071404": 1, "reaction_10048567": 5, "species_10048564": 4, "E1BB11": 2, "ENSBTAT00000002235": 1, "F1MU00": 2, "ENSBTAT00000006073": 1, "E1B8Y0": 2, "ENSBTAT00000054801": 1, "reaction_10048550": 5, "species_425978": 1, "species_425971": 1, "species_10048547": 2, "ENSBTAT00000073706": 1, "reaction_10058841": 5, "species_1498733": 3, "species_10058838": 3, "ENSBTAT00000068283": 1, "reaction_10059000": 5, "species_10058905": 6, "reaction_10059851": 5, "species_426658": 6, "species_1602420": 1, "reaction_10058874": 5, "species_1498737": 2, "reaction_10058975": 5, "species_10058972": 4, "reaction_10059026": 5, "species_10059023": 3, "reaction_10048682": 3, "species_10035250": 6, "species_10035235": 2, "reaction_10048717": 6, "species_10048700": 6, "species_427523": 4, "species_427497": 4, "species_10044309": 8, "species_427498": 3, "species_10048714": 9, "E1BJI1": 2, "ENSBTAT00000039795": 1, "F1MQB8": 4, "ENSBTAT00000018630": 2, "reaction_10048720": 5, "species_10048712": 6, "reaction_10044361": 3, "species_10044357": 7, "Q3SZ25": 9, "ENSBTAT00000010324": 1, "A0A3Q1MSK4": 9, "ENSBTAT00000084115": 1, "A0A3Q1M792": 9, "ENSBTAT00000077887": 1, "Q3MHL3": 15, "ENSBTAT00000007758": 1, "A0A3Q1LPJ7": 4, "ENSBTAT00000083404": 1, "F1N6Y2": 4, "ENSBTAT00000022557": 1, "species_10044359": 13, "reaction_10044381": 4, "species_10044378": 12, "reaction_10044333": 3, "species_10044307": 4, "A0A3Q1M9H4": 5, "ENSBTAT00000086443": 2, "A0A3Q1LVT5": 4, "ENSBTAT00000069734": 1, "A0A452DII9": 4, "ENSBTAT00000003549": 1, "species_10044329": 10, "species_10044331": 14, "reaction_10044390": 4, "species_10044387": 13, "reaction_10070700": 4, "species_5221062": 1, "species_10036698": 3, "ENSBTAT00000072242": 2, "species_10036706": 6, "A0A3Q1LSS4": 5, "species_5221065": 1, "reaction_10070702": 4, "species_5220996": 1, "species_5221064": 1, "reaction_10071065": 5, "species_113560": 9, "species_2485002": 9, "species_10071014": 6, "species_10071062": 23, "A5PJQ1": 2, "ENSBTAT00000017097": 1, "E1B6X6": 3, "ENSBTAT00000072070": 1, "E1BKX3": 2, "ENSBTAT00000009771": 1, "F1MX61": 2, "ENSBTAT00000011734": 1, "A0A3Q1M384": 5, "ENSBTAT00000070441": 1, "F6QHI8": 2, "ENSBTAT00000019351": 1, "Q1JQD6": 2, "ENSBTAT00000043676": 1, "Q32LB6": 2, "ENSBTAT00000004611": 1, "F1MUD5": 2, "ENSBTAT00000056158": 1, "reaction_10065336": 3, "species_10065332": 2, "species_10065308": 2, "ENSBTAT00000075583": 2, "species_10065334": 3, "A0A3Q1LJU9": 2, "reaction_10065435": 3, "species_10065431": 5, "F1MLT0": 3, "ENSBTAT00000060945": 1, "E1B8X7": 3, "ENSBTAT00000001312": 1, "F1MT44": 3, "ENSBTAT00000005807": 1, "species_10065433": 6, "reaction_10064435": 3, "species_10064421": 5, "A0A3Q1MN12": 3, "ENSBTAT00000070645": 1, "E1BLS8": 3, "ENSBTAT00000015049": 1, "species_10064431": 3, "P55918": 3, "ENSBTAT00000008130": 1, "Q5EA98": 3, "ENSBTAT00000022877": 1, "species_10064433": 7, "reaction_10063839": 2, "species_10063825": 2, "reaction_10064437": 2, "species_10059655": 2, "species_10063809": 2, "reaction_10067346": 3, "species_10067343": 3, "E1BNX9": 2, "ENSBTAT00000008077": 1, "A0A3Q1M0Y5": 2, "ENSBTAT00000075032": 1, "reaction_10092050": 4, "species_10092047": 2, "G5E522": 3, "ENSBTAT00000002668": 1, "species_10067330": 7, "E1BKA8": 16, "ENSBTAT00000024511": 5, "E1BGC6": 9, "ENSBTAT00000082389": 2, "reaction_10067332": 4, "species_10067306": 16, "G3MY82": 2, "ENSBTAT00000065500": 2, "E1BPC8": 2, "ENSBTAT00000019509": 1, "G3N2S2": 2, "ENSBTAT00000066065": 1, "Q5EA32": 2, "ENSBTAT00000003922": 1, "A0A3Q1M893": 8, "ENSBTAT00000074148": 1, "F1MPF0": 2, "ENSBTAT00000044081": 1, "P79100": 2, "ENSBTAT00000065392": 1, "E1BAN3": 2, "ENSBTAT00000033438": 1, "F1N232": 2, "ENSBTAT00000068680": 1, "E1BDG0": 2, "ENSBTAT00000022589": 1, "E1BCP0": 2, "ENSBTAT00000085000": 1, "E1B6Y9": 2, "ENSBTAT00000002485": 1, "reaction_10039604": 5, "species_10039233": 6, "E1BME0": 4, "ENSBTAT00000021691": 1, "Q2KIJ0": 4, "ENSBTAT00000021633": 1, "Q3SZI5": 4, "ENSBTAT00000004810": 1, "species_170037": 5, "reaction_10039240": 2, "species_10039235": 6, "species_166216": 3, "species_10039237": 6, "reaction_10039242": 3, "species_166213": 1, "reaction_10039254": 3, "reaction_10073400": 8, "species_10073398": 1, "species_10066894": 2, "species_29478": 18, "species_10069751": 5, "ENSBTAT00000025492": 1, "reaction_10066651": 4, "species_10066642": 5, "species_10066644": 8, "species_10066648": 3, "ENSBTAT00000076721": 1, "reaction_10073402": 4, "species_10069756": 5, "reaction_10069754": 8, "reaction_10073404": 8, "species_10070273": 6, "species_10035060": 5, "reaction_10073406": 8, "species_10070419": 4, "reaction_10069747": 8, "species_10069723": 3, "species_10069744": 3, "ENSBTAT00000080313": 1, "reaction_10073394": 8, "species_10069811": 2, "species_10069721": 4, "species_10069737": 6, "A0A3Q1MT70": 2, "ENSBTAT00000078784": 1, "E1BB12": 2, "ENSBTAT00000002234": 1, "E1BPL5": 6, "ENSBTAT00000002687": 2, "A0A3Q1MI23": 2, "ENSBTAT00000070121": 1, "reaction_10073396": 8, "species_10072792": 1, "species_10069777": 2, "species_10069793": 4, "G3N2E9": 2, "ENSBTAT00000063826": 1, "G3N346": 3, "ENSBTAT00000063022": 2, "reaction_10069719": 8, "species_10069712": 4, "species_10069716": 4, "reaction_10069769": 8, "species_10069766": 4, "A0A3Q1MZ57": 2, "ENSBTAT00000071767": 1, "F1MUR2": 3, "ENSBTAT00000028871": 2, "reaction_10073384": 8, "species_10070949": 2, "reaction_10069740": 8, "reaction_10073380": 8, "species_10072735": 3, "reaction_10069796": 8, "species_10069785": 2, "reaction_10073382": 8, "reaction_10069937": 5, "species_10069934": 8, "F1MUT0": 2, "ENSBTAT00000004658": 1, "Q2NKU6": 12, "ENSBTAT00000012183": 1, "E1BLX2": 12, "ENSBTAT00000070677": 1, "F1MHA1": 12, "ENSBTAT00000024084": 1, "reaction_10072752": 5, "species_10069843": 3, "ENSBTAT00000034204": 1, "reaction_10072755": 5, "species_10044337": 5, "reaction_10069939": 3, "species_10069830": 2, "ENSBTAT00000000107": 2, "species_10069834": 2, "ENSBTAT00000086218": 2, "species_10069836": 4, "A0A3Q1M7L9": 2, "E1BKH5": 2, "reaction_10070962": 6, "species_10070959": 9, "Q0P5C5": 3, "ENSBTAT00000047138": 1, "G3X834": 2, "ENSBTAT00000056084": 1, "species_10070404": 2, "reaction_10072725": 5, "species_10072722": 8, "reaction_10072788": 5, "species_10072771": 2, "species_10072786": 1, "species_10072775": 4, "ENSBTAT00000082174": 1, "reaction_10072823": 5, "species_10072800": 4, "species_10072821": 3, "species_10072810": 4, "A0A3Q1M6A7": 2, "ENSBTAT00000075432": 1, "A0A3Q1MID6": 2, "ENSBTAT00000070396": 1, "reaction_10069846": 5, "reaction_10072790": 5, "species_10072763": 2, "reaction_10072778": 5, "reaction_10072813": 5, "species_10064889": 3, "reaction_10072655": 5, "species_10072636": 1, "species_10072642": 1, "species_10072652": 3, "F1MTF1": 2, "ENSBTAT00000025245": 1, "reaction_10069838": 6, "species_10069825": 4, "F1N6Y5": 2, "ENSBTAT00000022553": 1, "F1MXG0": 2, "ENSBTAT00000009641": 1, "A0A452DJ38": 2, "ENSBTAT00000013472": 1, "reaction_10072750": 5, "species_10072743": 1, "species_10072747": 2, "ENSBTAT00000084416": 1, "reaction_10068699": 6, "species_10068652": 3, "species_10068658": 5, "species_5566518": 3, "species_10068694": 11, "A0A3Q1MMC8": 3, "ENSBTAT00000063281": 1, "E1B806": 3, "ENSBTAT00000020692": 1, "Q0VC01": 3, "ENSBTAT00000075111": 1, "A0A3Q1MC43": 3, "ENSBTAT00000075576": 1, "Q1LZE0": 3, "ENSBTAT00000023526": 1, "E1BGK1": 3, "ENSBTAT00000025155": 1, "F1MFL5": 3, "ENSBTAT00000005222": 1, "species_10068697": 11, "reaction_10068844": 5, "species_10044720": 2, "ENSBTAT00000070733": 1, "reaction_10091745": 3, "species_9679795": 1, "reaction_10068725": 5, "species_10068722": 8, "CHEBI:57627": 1, "reaction_10068569": 5, "species_10068132": 1, "species_10068566": 1, "reaction_10067596": 5, "species_10067575": 3, "species_10067593": 4, "F1MP98": 2, "ENSBTAT00000013893": 1, "F1MRF9": 2, "ENSBTAT00000000991": 1, "E1BFW0": 2, "ENSBTAT00000030541": 1, "reaction_10071886": 3, "species_10071878": 2, "species_10071882": 2, "ENSBTAT00000013131": 2, "species_10071884": 3, "F1MTX0": 2, "reaction_10070409": 5, "species_10070394": 1, "species_10070406": 3, "A0A3Q1LQR4": 4, "ENSBTAT00000066577": 2, "Q5E9L5": 11, "ENSBTAT00000009750": 2, "reaction_10070377": 5, "species_10070328": 1, "species_10070374": 1, "species_10070277": 3, "reaction_10070520": 3, "species_10044297": 2, "species_10070518": 4, "reaction_10073416": 5, "species_10073414": 3, "species_10070279": 4, "A0A3Q1MR38": 2, "ENSBTAT00000068896": 2, "reaction_10070392": 5, "species_10070379": 1, "species_10070389": 1, "species_10047781": 3, "reaction_10070282": 5, "reaction_10070896": 5, "species_10070848": 1, "species_10070894": 1, "reaction_10070757": 5, "species_10070745": 1, "species_10070755": 1, "reaction_10070516": 5, "species_10070467": 1, "species_10070513": 1, "species_10066655": 2, "reaction_10056383": 5, "species_1183111": 1, "species_1183191": 1, "species_10056380": 6, "A6QLC1": 2, "ENSBTAT00000015977": 1, "F1N048": 4, "ENSBTAT00000004411": 1, "E1BD46": 2, "ENSBTAT00000015978": 1, "E1BCN3": 3, "ENSBTAT00000015991": 1, "reaction_10066966": 5, "species_10066920": 1, "species_10066951": 1, "species_76230": 1, "species_10066963": 2, "reaction_10092108": 8, "species_10092095": 7, "species_10092091": 14, "P35833": 4, "ENSBTAT00000028610": 1, "A0A3Q1MYA3": 4, "ENSBTAT00000072313": 1, "species_10055212": 2, "species_10055148": 2, "species_10055146": 2, "species_10055162": 2, "species_10092105": 9, "reaction_10092257": 2, "species_10092255": 8, "reaction_10073690": 3, "species_10073673": 15, "E1BL08": 12, "ENSBTAT00000009316": 4, "F1MTC1": 7, "ENSBTAT00000009960": 2, "E1BIP0": 9, "ENSBTAT00000011745": 1, "F1MX43": 7, "ENSBTAT00000045584": 1, "A0A3Q1LHY0": 6, "ENSBTAT00000081383": 2, "F1MJD0": 6, "ENSBTAT00000037660": 2, "B0LKN7": 9, "ENSBTAT00000065347": 1, "A6QQ46": 7, "ENSBTAT00000020355": 2, "Q06600": 7, "ENSBTAT00000000018": 1, "E1BK50": 7, "ENSBTAT00000027554": 1, "F1N0K4": 9, "ENSBTAT00000045141": 1, "species_10073687": 16, "reaction_10074280": 3, "species_10074276": 3, "E1BF06": 4, "ENSBTAT00000036452": 2, "species_10074270": 2, "ENSBTAT00000028109": 2, "species_10074278": 4, "A6QPW7": 2, "reaction_10074266": 3, "species_10074262": 2, "ENSBTAT00000064406": 2, "species_10074258": 2, "ENSBTAT00000079425": 2, "species_10074264": 3, "A0A3Q1M9X1": 2, "Q08DT5": 2, "reaction_10076237": 3, "species_10074274": 2, "species_10076233": 2, "ENSBTAT00000085571": 2, "species_10076235": 3, "A0A3Q1LIC4": 2, "reaction_10073765": 3, "species_10073621": 3, "species_10073761": 2, "ENSBTAT00000009759": 2, "species_10073763": 3, "A5D7R1": 2, "reaction_10076165": 3, "species_10076161": 2, "E1BGY4": 3, "ENSBTAT00000003763": 1, "species_10076155": 2, "ENSBTAT00000066801": 2, "species_10076163": 3, "A0A3Q1M5M3": 2, "reaction_10074340": 3, "species_10074326": 3, "Q3ZBM0": 4, "ENSBTAT00000000141": 3, "species_10074336": 3, "F1MU29": 3, "ENSBTAT00000020341": 1, "A0A3Q1M673": 3, "ENSBTAT00000085489": 1, "species_10074338": 5, "reaction_10074312": 3, "species_10073669": 6, "species_10073585": 8, "species_10073671": 9, "reaction_10074314": 3, "species_10073623": 4, "species_10073625": 7, "reaction_10073757": 3, "species_10073601": 2, "species_10073597": 2, "species_10073603": 4, "reaction_10074316": 3, "species_10073637": 4, "species_10073639": 7, "reaction_10074318": 3, "species_10073605": 7, "reaction_10074320": 3, "species_10073635": 2, "species_10073629": 2, "reaction_10074306": 3, "species_10073609": 3, "species_10074304": 4, "reaction_10074308": 3, "species_10073667": 5, "species_10073643": 2, "reaction_10074310": 3, "reaction_10073699": 3, "species_10073696": 15, "reaction_10071948": 2, "species_10047524": 5, "reaction_10073708": 4, "species_10073705": 2, "reaction_10071982": 4, "species_10071979": 4, "A7MBB7": 6, "ENSBTAT00000007904": 1, "F1MBB0": 6, "ENSBTAT00000055496": 1, "species_10071971": 5, "reaction_10072030": 2, "species_10071991": 3, "species_10072028": 3, "reaction_10071975": 3, "species_10056243": 6, "species_10071973": 7, "reaction_10057834": 3, "species_10054520": 7, "A0A3Q1LZG1": 11, "P01239": 8, "ENSBTAT00000020313": 1, "A0A3Q1M283": 9, "ENSBTAT00000082398": 1, "species_10054522": 11, "reaction_10054524": 4, "species_10054501": 4, "species_10054509": 4, "species_10054511": 10, "reaction_10060412": 2, "reaction_10057836": 4, "reaction_10057823": 2, "species_10054507": 3, "reaction_10056335": 3, "species_10056333": 6, "reaction_10054791": 5, "species_10054785": 6, "species_10054789": 6, "reaction_10054779": 2, "species_10054777": 2, "reaction_10056268": 4, "species_10056255": 4, "species_10056265": 4, "reaction_10090844": 6, "species_10084303": 4, "species_10036552": 14, "species_10090842": 3, "species_10090840": 2, "reaction_10092151": 3, "species_10037584": 5, "species_10092149": 4, "reaction_10092159": 4, "species_10092135": 5, "species_10092156": 4, "reaction_10077790": 3, "species_10036540": 2, "species_10077786": 3, "species_10077788": 4, "reaction_10084305": 3, "reaction_10092040": 6, "species_10092037": 3, "species_10080697": 2, "ENSBTAT00000081330": 2, "reaction_10092139": 3, "species_10055924": 2, "ENSBTAT00000079236": 2, "species_10092112": 5, "A0A3Q1MQG1": 4, "reaction_10092173": 4, "species_10092110": 5, "species_10092170": 4, "reaction_10092141": 3, "species_10092116": 2, "ENSBTAT00000081400": 2, "species_10092118": 5, "A0A3Q1MHK8": 2, "reaction_10092143": 3, "species_10092122": 2, "ENSBTAT00000026137": 2, "species_10092124": 5, "Q5BIM7": 2, "reaction_10092126": 6, "reaction_10092147": 3, "species_10087926": 2, "species_10092145": 4, "reaction_10092195": 2, "species_10092178": 4, "species_10092193": 3, "reaction_10092183": 4, "species_10092180": 4, "reaction_10092137": 3, "reaction_10092043": 5, "species_10040499": 3, "species_10083560": 2, "reaction_10092033": 3, "species_10036565": 5, "species_10065275": 6, "reaction_10092133": 3, "species_10046947": 3, "ENSBTAT00000020161": 2, "species_10092131": 4, "E1BKA6": 9, "reaction_10092165": 3, "species_10092161": 4, "species_10092163": 5, "reaction_10090916": 3, "species_10036554": 4, "species_10074033": 6, "reaction_10090919": 5, "reaction_10052217": 6, "species_10052144": 14, "Q04790": 12, "ENSBTAT00000029080": 1, "E1B7E8": 11, "ENSBTAT00000053863": 1, "E1BDZ1": 11, "ENSBTAT00000030158": 1, "F1N6A7": 11, "ENSBTAT00000054467": 1, "A0A3Q1MMI8": 11, "ENSBTAT00000073168": 1, "G3MYH9": 11, "ENSBTAT00000064849": 1, "A0A3Q1LPD3": 11, "ENSBTAT00000066449": 1, "A0A3Q1LZ20": 11, "ENSBTAT00000085216": 1, "species_10052194": 15, "reaction_10052347": 3, "species_10052187": 6, "Q58DC4": 4, "ENSBTAT00000036455": 2, "reaction_10052189": 3, "species_10052169": 5, "species_10052181": 4, "reaction_10055946": 5, "species_10055943": 13, "reaction_10055955": 5, "species_10052222": 14, "species_10055948": 13, "reaction_10055958": 5, "species_10052206": 14, "reaction_10052159": 3, "species_10052140": 2, "species_10052153": 14, "species_10052157": 13, "reaction_10070719": 3, "species_10070711": 2, "A5H027": 5, "ENSBTAT00000044248": 2, "species_10070715": 2, "ENSBTAT00000048747": 3, "species_10070717": 3, "A4IFE6": 3, "reaction_10052147": 5, "reaction_10052210": 4, "species_10052204": 10, "species_10052200": 4, "species_10052208": 4, "reaction_10052213": 3, "species_10052167": 4, "species_10052163": 2, "reaction_10052233": 4, "reaction_10091725": 3, "species_9678619": 1, "reaction_10052236": 4, "reaction_10052229": 5, "species_10052227": 14, "reaction_10052196": 3, "reaction_10056297": 8, "species_10056278": 10, "O02741": 13, "ENSBTAT00000019573": 2, "A0A452DII5": 7, "ENSBTAT00000017267": 2, "A2VEA3": 5, "ENSBTAT00000008822": 1, "A0A3Q1LPN8": 11, "ENSBTAT00000083455": 1, "species_10056293": 2, "ENSBTAT00000050064": 2, "species_10056295": 3, "O62830": 2, "species_10056276": 7, "species_10053116": 5, "reaction_10056315": 8, "species_10056311": 7, "F1MM71": 3, "ENSBTAT00000010366": 1, "species_10056313": 8, "reaction_10056283": 8, "species_10039246": 2, "ENSBTAT00000031869": 3, "species_10056280": 3, "Q4JF28": 15, "reaction_10060730": 4, "species_10060726": 6, "A0A3Q1MFK0": 3, "ENSBTAT00000075646": 1, "A0A3Q1M8U3": 3, "ENSBTAT00000086252": 1, "Q2NL22": 5, "ENSBTAT00000021327": 1, "Q3SZ54": 3, "ENSBTAT00000000144": 1, "species_10060706": 8, "A0A3Q1LSC2": 4, "ENSBTAT00000086202": 2, "A0A3Q1MRS1": 4, "species_10060724": 6, "species_10060728": 7, "reaction_10060732": 3, "species_10060704": 3, "reaction_10056287": 8, "species_10055358": 2, "species_10056285": 3, "reaction_10056289": 3, "species_10056270": 3, "reaction_10060694": 4, "species_141681": 1, "species_10060689": 2, "ENSBTAT00000086230": 1, "reaction_10089341": 3, "species_10053104": 3, "species_10089337": 2, "ENSBTAT00000004270": 2, "species_10089339": 3, "F1MXX7": 2, "reaction_10089696": 3, "species_170292": 1, "species_9009945": 1, "species_10089693": 3, "reaction_10089349": 3, "species_10089345": 2, "species_10089343": 2, "species_10089347": 3, "reaction_10089703": 6, "species_8983696": 2, "species_10089700": 2, "ENSBTAT00000020675": 1, "reaction_10057588": 3, "species_10057585": 4, "A0A3Q1LQ50": 2, "ENSBTAT00000074252": 1, "E1BGH7": 2, "ENSBTAT00000011399": 1, "F1MLI5": 2, "ENSBTAT00000025779": 1, "reaction_10091423": 3, "species_9647661": 1, "species_10037243": 7, "ENSBTAT00000087110": 8, "species_10091421": 3, "A0A3Q1MD51": 12, "species_8954419": 6, "reaction_10092350": 4, "species_10091431": 4, "species_10092343": 2, "species_10092345": 2, "species_10092347": 2, "reaction_10091409": 4, "species_10081899": 6, "species_1806180": 9, "species_10081901": 6, "species_10091407": 3, "reaction_10081905": 4, "species_10044670": 2, "ENSBTAT00000024094": 3, "species_10081502": 4, "species_10081903": 6, "E1BFC3": 4, "ENSBTAT00000080428": 4, "reaction_10092341": 4, "species_10091433": 3, "species_10092338": 2, "O75601": 2, "ENSBTAT00000027820": 1, "reaction_10091415": 3, "species_5620974": 6, "species_10091413": 6, "reaction_10091439": 5, "species_10091437": 2, "reaction_10091425": 4, "reaction_10092352": 3, "species_10091427": 6, "species_10037249": 5, "reaction_10092354": 4, "species_10091417": 2, "species_10091419": 2, "reaction_10091429": 3, "reaction_10037253": 5, "species_10037239": 3, "species_10037211": 2, "species_10037235": 4, "Q05KI7": 3, "ENSBTAT00000000549": 2, "species_10037245": 4, "species_10037251": 4, "reaction_10092356": 3, "reaction_10092358": 3, "reaction_10091817": 3, "species_9678991": 1, "species_10091815": 2, "reaction_10056239": 5, "species_10056236": 4, "reaction_10044568": 4, "species_10044551": 2, "ENSBTAT00000023373": 3, "species_10044555": 2, "species_10044553": 2, "species_10044565": 5, "G3X702": 3, "ENSBTAT00000016642": 1, "reaction_10090575": 2, "species_10044753": 3, "reaction_10044578": 4, "species_10044572": 2, "species_10044576": 2, "species_10044574": 2, "reaction_10036080": 3, "species_10036074": 15, "A0A3Q1MM18": 7, "ENSBTAT00000086549": 1, "A0A3Q1LW50": 7, "ENSBTAT00000076380": 3, "E1BHK8": 7, "F1N150": 7, "Q3T0Z8": 7, "ENSBTAT00000021643": 1, "A4IFN1": 4, "ENSBTAT00000033237": 1, "Q3ZBL0": 7, "ENSBTAT00000007241": 1, "F1MKH0": 4, "ENSBTAT00000013683": 1, "A0A3Q1M973": 7, "ENSBTAT00000001380": 1, "F1N038": 4, "ENSBTAT00000016000": 1, "A0A3Q1N0Z1": 4, "ENSBTAT00000074628": 2, "species_10036078": 4, "species_10036072": 14, "reaction_10036915": 3, "species_10036911": 14, "species_10036913": 3, "reaction_10083967": 3, "species_8851965": 2, "species_10083963": 2, "ENSBTAT00000049415": 2, "species_10083965": 2, "A6QNP4": 2, "reaction_10083959": 3, "species_10083955": 2, "ENSBTAT00000045031": 2, "species_10083957": 2, "F1MZI6": 2, "reaction_10046811": 3, "species_10046779": 3, "A0A3Q1ND77": 11, "ENSBTAT00000079588": 1, "species_10046793": 2, "A0A3S5ZP81": 14, "ENSBTAT00000079899": 1, "species_10046809": 3, "reaction_10046907": 6, "species_10037459": 4, "species_10046905": 4, "A0A3Q1MLL9": 13, "ENSBTAT00000081673": 2, "species_10046818": 7, "species_10043788": 7, "reaction_10047530": 5, "species_10047527": 2, "species_10047008": 2, "ENSBTAT00000080762": 1, "reaction_10046932": 5, "species_10046929": 6, "reaction_10046787": 3, "species_10046783": 2, "species_10046785": 3, "reaction_10046943": 5, "species_10046936": 7, "species_10046940": 7, "reaction_10046822": 3, "species_10046820": 6, "reaction_10046951": 3, "species_10046949": 6, "reaction_10046834": 3, "species_10046830": 2, "ENSBTAT00000019810": 2, "species_10046826": 2, "ENSBTAT00000028775": 2, "species_10046832": 3, "Q58DF9": 2, "E1BCU8": 2, "reaction_10046909": 6, "species_10046805": 5, "Q28090": 6, "ENSBTAT00000017527": 1, "species_10046899": 9, "reaction_10046959": 3, "species_10046801": 2, "species_10046803": 3, "reaction_10046807": 3, "species_10046795": 3, "reaction_10046903": 3, "species_10046901": 9, "reaction_10075923": 2, "species_10075919": 2, "ENSBTAT00000081458": 2, "species_10075921": 2, "A0A3Q1NI55": 2, "reaction_10065019": 3, "species_10065015": 15, "A0A3Q1MEG8": 14, "ENSBTAT00000074178": 2, "Q30309": 20, "ENSBTAT00000014072": 1, "A6H6Y1": 20, "ENSBTAT00000019939": 1, "A6QQE7": 20, "ENSBTAT00000003342": 1, "E1BLZ1": 20, "ENSBTAT00000034283": 1, "F1N0X9": 20, "ENSBTAT00000019800": 1, "F1N610": 20, "ENSBTAT00000026100": 1, "F1MJU5": 20, "ENSBTAT00000018484": 1, "A0A3Q1MI49": 20, "ENSBTAT00000085256": 2, "A0A3Q1MUX0": 20, "ENSBTAT00000078884": 1, "F1ML60": 20, "A0A3Q1M088": 20, "ENSBTAT00000075226": 1, "G3MWT2": 20, "ENSBTAT00000064718": 1, "Q70IB5": 20, "ENSBTAT00000063954": 1, "species_10064164": 15, "species_10065017": 15, "reaction_10064219": 3, "species_10063931": 15, "species_10063937": 16, "species_10064216": 2, "P25326": 7, "ENSBTAT00000022774": 1, "reaction_10065051": 4, "species_10065047": 19, "F1MHT7": 3, "ENSBTAT00000008504": 1, "Q5KTP6": 3, "ENSBTAT00000065976": 1, "F1MLV2": 3, "ENSBTAT00000020881": 1, "Q58DW7": 3, "ENSBTAT00000016520": 1, "species_2213226": 2, "species_10065045": 6, "species_10065049": 14, "reaction_10065021": 3, "species_10064275": 22, "species_10064116": 16, "species_10064225": 8, "reaction_10064221": 3, "species_2213225": 1, "species_10063969": 5, "Q0VCU3": 2, "ENSBTAT00000014587": 1, "reaction_10065055": 4, "species_10063941": 16, "species_10065053": 2, "reaction_10065009": 2, "species_10065007": 15, "species_10063925": 15, "reaction_10084401": 3, "species_10064210": 14, "species_10084397": 2, "ENSBTAT00000077596": 2, "species_10084399": 15, "A0A3Q1LYZ8": 2, "reaction_10065011": 3, "species_10064162": 9, "species_10064138": 6, "reaction_10064277": 3, "species_10064223": 15, "reaction_10064118": 2, "species_10064020": 16, "reaction_10064214": 2, "species_10064066": 16, "species_10064212": 15, "reaction_10064068": 2, "reaction_10063972": 3, "reaction_10042635": 3, "species_10042631": 2, "ENSBTAT00000027169": 2, "species_10042627": 2, "ENSBTAT00000001635": 2, "species_10042633": 3, "A5D7V5": 2, "Q3ZC60": 2, "reaction_10042253": 3, "species_10042245": 3, "F1MEF6": 3, "ENSBTAT00000012194": 1, "F6RKH9": 3, "ENSBTAT00000025279": 1, "species_10042249": 2, "ENSBTAT00000068738": 2, "species_10042251": 4, "A0A3Q1MBF2": 2, "reaction_10042623": 3, "species_10042615": 2, "ENSBTAT00000076490": 2, "species_10042619": 2, "ENSBTAT00000083396": 2, "species_10042621": 3, "A0A3Q1M4X8": 8, "A7YWT5": 2, "reaction_10042129": 3, "species_10042125": 12, "F1MC47": 3, "ENSBTAT00000046313": 1, "A0A3Q1M3D2": 3, "ENSBTAP00000064618": 1, "F1MBP3": 3, "ENSBTAT00000050022": 1, "A0A3Q1MT21": 3, "ENSBTAT00000067721": 1, "F1MJB8": 3, "ENSBTAT00000054092": 1, "E1BLJ5": 3, "ENSBTAT00000055909": 1, "A0A3Q1MYX4": 3, "ENSBTAT00000085379": 1, "Q0VCU4": 3, "ENSBTAT00000016878": 1, "Q28072": 5, "ENSBTAT00000008462": 1, "A7MAZ7": 3, "ENSBTAT00000028175": 1, "A7YW30": 3, "ENSBTAT00000033046": 1, "species_10042127": 22, "reaction_10074993": 3, "species_1006168": 4, "species_10074989": 6, "A0A3Q1MHX4": 9, "ENSBTAT00000081728": 1, "G3MZR7": 9, "ENSBTAT00000064604": 1, "E1B8E5": 9, "ENSBTAT00000052760": 1, "E1BKZ8": 9, "ENSBTAT00000011656": 1, "F1MST2": 9, "ENSBTAT00000031802": 1, "species_10074991": 7, "reaction_10075009": 3, "species_10074999": 2, "A5PJG8": 3, "ENSBTAT00000042955": 1, "species_10075005": 2, "A0A3Q1NBN7": 3, "ENSBTAT00000082969": 1, "species_10075007": 3, "reaction_10084672": 3, "species_10084640": 2, "ENSBTAT00000001412": 2, "species_10084668": 3, "E1B7F4": 3, "ENSBTAT00000017867": 1, "A6H6Y6": 3, "ENSBTAT00000065575": 1, "species_10084670": 4, "F1MJX3": 4, "reaction_10074899": 3, "species_10074895": 3, "F1MLN1": 3, "ENSBTAT00000034482": 2, "species_10074889": 3, "Q3ZBB1": 3, "ENSBTAT00000036966": 1, "A0A3Q1M4F1": 3, "ENSBTAT00000085516": 1, "species_10074897": 4, "reaction_10076963": 3, "species_5696348": 4, "species_1500646": 12, "species_10076959": 10, "F1MNL2": 3, "ENSBTAT00000020853": 1, "E1BI56": 3, "ENSBTAT00000008500": 1, "F1MGI2": 3, "ENSBTAT00000010642": 1, "E1BFU3": 7, "ENSBTAT00000040027": 1, "A0A3Q1ML46": 7, "ENSBTAT00000071567": 1, "A0A3Q1LX01": 3, "ENSBTAT00000070885": 1, "F1MG16": 3, "ENSBTAT00000003593": 1, "A0A3Q1MT87": 3, "ENSBTAT00000077738": 1, "species_10076961": 13, "reaction_10042786": 3, "species_10042782": 11, "species_10042780": 9, "G5E5W5": 3, "ENSBTAT00000011326": 2, "Q8SPQ5": 3, "ENSBTAT00000080712": 1, "A0A3Q1ME80": 3, "ENSBTAT00000077038": 1, "A0A3Q1MQ30": 3, "ENSBTAT00000081128": 1, "F1MQD8": 3, "ENSBTAT00000053352": 1, "G3X797": 3, "ENSBTAT00000022538": 1, "G5E5B4": 3, "G5E5G6": 3, "ENSBTAT00000018094": 1, "species_10042784": 19, "reaction_10084658": 3, "species_10084654": 2, "ENSBTAT00000087222": 2, "species_10084650": 3, "A0A3Q1MN37": 3, "ENSBTAT00000072757": 1, "species_10084656": 4, "A0A3Q1NN33": 2, "reaction_10074901": 2, "species_10074893": 2, "reaction_10043241": 3, "species_10043234": 2, "species_10043239": 3, "reaction_10043262": 5, "species_10043259": 3, "A0A3Q1MMD9": 11, "ENSBTAT00000074574": 5, "reaction_10043193": 3, "species_10043189": 2, "ENSBTAT00000074583": 2, "species_10043191": 6, "A0A3Q1MCW9": 2, "reaction_10043225": 3, "species_10043006": 2, "species_10043223": 4, "reaction_10043219": 5, "species_202247": 6, "species_10043216": 3, "reaction_10043252": 3, "species_10043248": 2, "ENSBTAT00000081933": 5, "species_10043180": 6, "species_1806238": 13, "species_10043250": 6, "A0A3S5ZPB2": 15, "reaction_10043304": 3, "species_10043279": 2, "species_10043295": 7, "species_10043281": 6, "reaction_10043274": 3, "species_10043267": 6, "species_10043265": 2, "species_10043272": 6, "reaction_10043244": 5, "reaction_10043212": 5, "species_10043202": 5, "species_10043209": 4, "reaction_10043182": 3, "species_202277": 3, "reaction_10043298": 5, "species_10043293": 7, "species_10041331": 2, "ENSBTAT00000020312": 1, "reaction_10043300": 3, "reaction_10043270": 5, "reaction_10043302": 3, "species_10043287": 6, "species_10043289": 7, "reaction_10055448": 3, "species_10055446": 57, "A0A3Q1LK96": 5, "ENSBTAT00000068172": 1, "A0A3Q1M231": 5, "ENSBTAT00000070128": 1, "A0A3Q1LV49": 5, "ENSBTAT00000082004": 1, "Q1RMK0": 5, "ENSBTAT00000010691": 1, "F1N7A0": 5, "ENSBTAT00000015476": 1, "M5FKI3": 5, "ENSBTAT00000070499": 1, "Q4U5R4": 5, "ENSBTAT00000039156": 1, "Q7YRV4": 6, "ENSBTAT00000018459": 2, "F1MEX6": 5, "ENSBTAT00000010969": 1, "E1BBI7": 5, "ENSBTAT00000081934": 1, "A0A3Q1MUP8": 5, "ENSBTAT00000079583": 1, "F1N0S2": 5, "ENSBTAT00000000291": 1, "G3X7V0": 5, "ENSBTAT00000009741": 1, "F1N7C1": 5, "ENSBTAT00000027362": 1, "F1N5X8": 5, "ENSBTAT00000048180": 1, "E1B964": 5, "ENSBTAT00000012816": 1, "A6QQD1": 6, "ENSBTAT00000005377": 1, "E1BCZ2": 5, "ENSBTAT00000012423": 1, "species_983123": 1, "species_10055330": 58, "reaction_10055451": 7, "species_10055428": 60, "species_10055422": 6, "A0A3Q1N1X1": 4, "ENSBTAT00000076465": 1, "species_10055420": 3, "reaction_10055453": 4, "species_983035": 1, "species_10055424": 61, "reaction_10055491": 4, "species_983036": 1, "species_8942986": 1, "species_10055488": 4, "E1BP91": 2, "ENSBTAT00000015199": 1, "E1BL29": 2, "ENSBTAT00000028490": 1, "reaction_10055431": 7, "reaction_10061657": 3, "species_10061653": 15, "Q50JB9": 10, "ENSBTAT00000072863": 1, "Q5W5I5": 8, "ENSBTAT00000069740": 1, "O02775": 8, "ENSBTAT00000009756": 1, "P25068": 8, "ENSBTAT00000074783": 7, "P46165": 8, "ENSBTAT00000018930": 1, "Q28880": 8, "ENSBTAT00000050266": 1, "F1MGE0": 8, "G3MWU3": 8, "G3MWY5": 8, "ENSBTAT00000064773": 1, "G3MXI5": 8, "A0A3Q1M0J5": 8, "ENSBTAT00000086067": 1, "A0A3Q1ME63": 8, "A0A452DIQ0": 8, "E1BHH4": 8, "species_10045084": 2, "species_10061655": 16, "reaction_10058456": 3, "species_10058452": 3, "species_1462049": 11, "species_10058454": 3, "reaction_10058492": 3, "species_10058488": 18, "A0A3Q1LWB5": 6, "ENSBTAT00000078433": 3, "A0A3Q1M5C9": 6, "A0A3Q1MT20": 6, "species_10058490": 19, "reaction_10058486": 2, "species_10058484": 18, "reaction_10063801": 5, "species_2090055": 2, "species_2090070": 1, "species_1678617": 3, "species_10060675": 4, "ENSBTAT00000075910": 1, "reaction_10063803": 5, "species_2090053": 2, "species_2065212": 3, "species_10060682": 3, "ENSBTAT00000071251": 1, "reaction_10060634": 5, "species_2090040": 1, "species_76183": 11, "species_2090069": 2, "species_10060631": 3, "A0A3Q1MIE9": 6, "ENSBTAT00000079230": 1, "reaction_10060685": 5, "species_2090080": 2, "reaction_10063805": 5, "species_2090045": 1, "reaction_10060671": 5, "species_10060650": 9, "species_2090023": 1, "species_10060664": 8, "species_10060668": 2, "ENSBTAT00000085333": 1, "reaction_10063022": 2, "species_10060394": 8, "reaction_10060625": 5, "species_10060622": 4, "F1N2D5": 2, "ENSBTAT00000014683": 1, "reaction_10060741": 6, "species_1678868": 3, "species_2090075": 1, "species_10060738": 4, "A3KMY8": 6, "ENSBTAT00000000941": 1, "species_427963": 3, "reaction_10060678": 5, "species_2090033": 1, "species_2090072": 1, "reaction_10072894": 5, "species_5653871": 1, "species_10072891": 4, "A0A3Q1LYQ2": 2, "ENSBTAT00000066421": 2, "reaction_10072898": 5, "species_10072896": 2, "species_10054442": 2, "species_5653875": 1, "reaction_10033611": 13, "species_29578": 11, "species_29800": 4, "species_10033608": 3, "P10096": 2, "ENSBTAT00000037753": 1, "Q2KJE5": 2, "ENSBTAT00000021166": 1, "reaction_10080765": 5, "species_10080762": 2, "A0A452DIC9": 2, "ENSBTAT00000000357": 1, "reaction_10033629": 9, "species_30014": 6, "species_10033626": 2, "A1A4J1": 6, "ENSBTAT00000056305": 1, "species_30533": 2, "species_76190": 2, "reaction_10034157": 10, "species_10034154": 5, "Q1JPG7": 2, "ENSBTAT00000086042": 1, "A5D984": 6, "ENSBTAT00000047412": 1, "reaction_10034140": 5, "species_29728": 4, "species_30485": 2, "species_10034049": 2, "Q3SZ62": 6, "ENSBTAT00000032937": 1, "reaction_10076815": 5, "species_70113": 15, "species_30537": 7, "species_10076812": 3, "A2VE47": 2, "ENSBTAT00000002065": 1, "reaction_10088737": 6, "species_8955759": 1, "species_10033547": 3, "A5PKH8": 3, "ENSBTAT00000001019": 1, "reaction_10033620": 5, "species_75970": 5, "species_10033617": 2, "A0A452DIX3": 2, "ENSBTAT00000026358": 1, "reaction_10034071": 7, "species_10034066": 3, "A0A3S5ZPB0": 8, "ENSBTAT00000017416": 1, "reaction_10078710": 3, "species_6798337": 1, "species_10078707": 2, "F1MX69": 2, "ENSBTAT00000070308": 1, "reaction_10045050": 9, "species_198498": 6, "species_10045047": 3, "ENSBTAT00000000538": 1, "reaction_10033757": 9, "reaction_10041885": 5, "species_113551": 9, "species_113782": 5, "species_10041882": 2, "ENSBTAT00000077820": 1, "reaction_10045692": 5, "species_10041875": 3, "P22292": 2, "ENSBTAT00000079666": 1, "reaction_10034238": 5, "species_113780": 3, "species_10034235": 2, "ENSBTAT00000013436": 1, "reaction_10045043": 6, "species_113573": 4, "species_372364": 1, "species_113525": 3, "species_10045040": 2, "ENSBTAT00000015834": 1, "reaction_10041878": 9, "reaction_10033718": 5, "species_76213": 3, "species_10033713": 3, "P33097": 2, "ENSBTAT00000015873": 1, "reaction_10067254": 5, "species_10067251": 2, "ENSBTAT00000005552": 1, "reaction_10067240": 5, "species_10067237": 2, "ENSBTAT00000069229": 1, "reaction_10067247": 5, "species_10067244": 2, "ENSBTAT00000021621": 1, "reaction_10045029": 5, "species_10045026": 3, "A0A3Q1M9V5": 2, "ENSBTAT00000083179": 1, "A0A3Q1LHX4": 2, "ENSBTAT00000073854": 1, "reaction_10033638": 6, "species_10033635": 3, "Q3SZB7": 2, "ENSBTAT00000012835": 1, "reaction_10033561": 7, "species_29532": 5, "species_31221": 1, "species_10033558": 2, "Q0II75": 2, "ENSBTAT00000015052": 1, "reaction_10083115": 7, "species_30393": 2, "species_6799497": 1, "species_10034172": 3, "reaction_10033570": 5, "species_10033567": 3, "A0A3Q1MGZ4": 2, "ENSBTAT00000085239": 1, "reaction_10072825": 6, "species_5652213": 1, "reaction_10063530": 5, "species_10063528": 4, "species_10063493": 4, "reaction_10063485": 2, "species_10063470": 4, "reaction_10063532": 5, "species_10063518": 4, "reaction_10063249": 5, "species_10063230": 4, "species_10063240": 4, "species_10063246": 6, "Q5EA01": 2, "ENSBTAT00000030023": 1, "reaction_10063232": 5, "species_10063222": 3, "reaction_10063520": 5, "reaction_10063477": 5, "species_10063464": 4, "species_10063474": 2, "ENSBTAT00000004844": 1, "reaction_10063508": 5, "species_10063505": 3, "E1BMN6": 2, "ENSBTAT00000015389": 1, "E1BK55": 2, "ENSBTAT00000056191": 1, "reaction_10060825": 5, "species_2065213": 2, "species_2065269": 3, "reaction_10091289": 5, "species_2105025": 3, "reaction_10060827": 5, "species_2104993": 1, "reaction_10060842": 4, "species_2065257": 5, "CHEBI:63512": 2, "CHEBI:63513": 2, "CHEBI:63515": 1, "species_2065239": 2, "species_10060839": 3, "F1MSK8": 2, "ENSBTAT00000000611": 1, "reaction_10060829": 5, "species_2065251": 3, "species_10060028": 4, "reaction_10062655": 4, "species_10062551": 7, "P21809": 24, "ENSBTAT00000047242": 2, "F1MY84": 23, "ENSBTAT00000016206": 1, "Q0VCM1": 23, "ENSBTAT00000002979": 1, "P21793": 24, "F1N2Y8": 23, "ENSBTAT00000002312": 1, "species_10062589": 7, "species_10062627": 6, "species_10062653": 6, "reaction_10060031": 5, "species_2065231": 1, "reaction_10063807": 5, "reaction_10061642": 5, "species_10061629": 7, "species_10061574": 8, "species_10061639": 3, "E1BMM8": 3, "ENSBTAT00000027366": 1, "F1N783": 3, "ENSBTAT00000019521": 1, "reaction_10061612": 5, "species_10061591": 6, "species_10061609": 5, "F1N663": 2, "ENSBTAT00000014069": 1, "A0A3Q1M362": 2, "ENSBTAT00000073469": 1, "A6QLZ9": 2, "ENSBTAT00000011567": 1, "A0A3Q1MTD8": 2, "ENSBTAT00000068924": 1, "reaction_10062463": 5, "species_10062450": 6, "species_10062460": 3, "G3X6P1": 2, "ENSBTAT00000010069": 1, "E1BPN4": 2, "ENSBTAT00000074793": 1, "reaction_10061651": 5, "species_1889970": 3, "species_10061557": 6, "species_10061648": 4, "E1B9D0": 2, "ENSBTAT00000019108": 1, "reaction_10063014": 2, "species_10063012": 6, "reaction_10061402": 5, "species_10061238": 14, "species_10061388": 14, "species_10061399": 2, "ENSBTAT00000035663": 1, "reaction_10061251": 5, "species_10061200": 13, "species_742361": 2, "species_10061248": 3, "F1N211": 2, "ENSBTAT00000007264": 1, "A0A3Q1LSF3": 2, "ENSBTAT00000070229": 1, "reaction_10061395": 5, "species_10061289": 15, "species_10061392": 2, "ENSBTAT00000057493": 1, "reaction_10061350": 5, "species_10061327": 14, "species_10061347": 5, "A0A3Q1M0B6": 2, "ENSBTAT00000083529": 1, "A0A3Q1LG25": 3, "ENSBTAT00000080834": 1, "F1MQ60": 2, "ENSBTAT00000070592": 1, "reaction_10091286": 5, "species_10061345": 3, "reaction_10062697": 5, "species_10062676": 6, "species_10062690": 6, "species_10062694": 2, "ENSBTAT00000005795": 1, "reaction_10062701": 2, "species_10062699": 6, "reaction_10062508": 3, "species_10062465": 6, "species_10062501": 6, "species_10062505": 2, "ENSBTAT00000056960": 1, "reaction_10062674": 5, "species_10062482": 6, "species_10062667": 6, "species_10062671": 2, "ENSBTAT00000068674": 1, "reaction_10039887": 5, "species_174370": 2, "species_158471": 18, "species_10039884": 4, "Q0VC88": 2, "ENSBTAT00000070040": 1, "F6R031": 2, "ENSBTAT00000017229": 1, "reaction_10039890": 5, "species_174375": 4, "reaction_10051570": 3, "species_10051567": 2, "ENSBTAT00000010620": 1, "reaction_10048727": 5, "species_427648": 2, "species_10048724": 2, "ENSBTAT00000019462": 1, "reaction_10064353": 3, "species_2142867": 1, "species_2142896": 2, "species_2162224": 10, "species_10064350": 2, "ENSBTAT00000071722": 1, "reaction_10064393": 4, "species_10064359": 2, "ENSBTAT00000070191": 2, "species_10064373": 4, "A0A3Q1MJE8": 4, "ENSBTAT00000080269": 1, "Q6UC88": 4, "ENSBTAT00000001061": 1, "F1MYW1": 4, "ENSBTAT00000007896": 1, "species_2160848": 2, "species_10064375": 6, "Q8SQG8": 3, "reaction_10091291": 5, "species_2162223": 3, "reaction_10064593": 5, "reaction_10064355": 4, "species_2160864": 2, "species_2160866": 3, "reaction_10064595": 5, "reaction_10064597": 5, "reaction_10064391": 3, "species_10064388": 9, "A0A3Q1LS44": 2, "ENSBTAT00000071051": 1, "species_2160894": 2, "reaction_10033579": 3, "species_29452": 1, "species_10033576": 3, "A0A452DIP2": 2, "ENSBTAT00000006586": 1, "reaction_10033594": 3, "species_10033549": 4, "F6QEU6": 7, "ENSBTAT00000007589": 1, "reaction_10090620": 5, "species_9033793": 3, "species_9033802": 1, "species_10090617": 3, "A0A3Q1M8N6": 5, "ENSBTAT00000081124": 1, "reaction_10090703": 5, "species_9036984": 4, "species_9037036": 1, "species_10090700": 4, "ENSBTAT00000028720": 1, "reaction_10090638": 5, "species_9034101": 2, "species_9034046": 1, "species_9037066": 1, "species_10090635": 3, "reaction_10090611": 5, "species_9033790": 3, "species_10090608": 2, "ENSBTAT00000023560": 1, "reaction_10090645": 5, "species_9034065": 1, "species_9037067": 1, "species_10090642": 3, "reaction_10090631": 5, "species_9033798": 1, "species_10090628": 3, "reaction_10090856": 5, "species_9605649": 2, "species_9605651": 1, "reaction_10090797": 5, "species_9605593": 2, "species_10090794": 4, "F1MDG4": 2, "ENSBTAT00000056091": 1, "F1MBS8": 3, "F1N751": 2, "ENSBTAT00000010501": 1, "reaction_10090799": 5, "species_9605607": 2, "reaction_10090819": 5, "species_9604808": 1, "species_10090816": 4, "Q2HJA3": 2, "ENSBTAT00000036248": 1, "F1MSJ4": 2, "ENSBTAT00000031889": 1, "Q3T0R9": 2, "ENSBTAT00000022206": 1, "reaction_10090851": 5, "species_9605685": 2, "species_10090848": 3, "reaction_10090867": 5, "species_9605661": 1, "species_10090864": 3, "G3MZR2": 2, "ENSBTAT00000066072": 1, "reaction_10090802": 5, "species_9605595": 3, "species_10054713": 2, "reaction_10090772": 5, "species_9605394": 1, "reaction_10090774": 5, "species_9605586": 1, "reaction_10090854": 5, "species_9605615": 1, "reaction_10090822": 5, "species_10069341": 2, "reaction_10034041": 9, "species_29790": 7, "species_29882": 3, "species_10034038": 5, "A7Z014": 2, "ENSBTAT00000004892": 1, "reaction_10033592": 6, "species_31467": 1, "species_10033589": 3, "A0A3Q1MM55": 2, "ENSBTAT00000067626": 1, "reaction_10034043": 9, "species_29878": 2, "reaction_10034013": 7, "species_29996": 1, "species_29732": 4, "species_10034010": 2, "A0A3S5ZPM3": 2, "ENSBTAT00000017988": 1, "reaction_10042801": 5, "species_10034029": 4, "A5D7P1": 2, "ENSBTAT00000082970": 1, "reaction_10034032": 3, "reaction_10088744": 5, "species_8955853": 1, "species_10088741": 2, "ENSBTAT00000044396": 1, "reaction_10089230": 3, "species_6787326": 1, "species_6787328": 1, "species_10033541": 4, "reaction_10077793": 3, "species_112016": 2, "reaction_10088898": 6, "species_8959707": 1, "species_10088895": 2, "ENSBTAT00000001095": 1, "reaction_10073438": 6, "species_5661264": 1, "species_5661268": 1, "species_10073435": 3, "ENSBTAT00000000630": 1, "reaction_10073431": 6, "species_5660036": 1, "species_5660033": 1, "species_10073428": 3, "A5PJR3": 2, "ENSBTAT00000085766": 2, "Q1JP75": 2, "reaction_10080747": 5, "species_6799540": 1, "species_429579": 1, "species_6799543": 1, "species_10080744": 3, "F1MWT0": 2, "ENSBTAT00000009690": 1, "reaction_10084129": 5, "species_8853396": 1, "species_6799577": 2, "species_6799594": 2, "species_10084126": 3, "Q29451": 4, "ENSBTAT00000070599": 1, "reaction_10080756": 5, "species_8853719": 1, "species_10080753": 3, "A0A3Q1MEZ5": 2, "ENSBTAT00000081381": 1, "reaction_10067610": 4, "species_10067605": 5, "A7MB78": 13, "ENSBTAT00000007423": 1, "A0A3Q1NLJ5": 22, "ENSBTAT00000077965": 1, "species_10067607": 5, "reaction_10067644": 5, "species_10067619": 5, "species_10067641": 5, "reaction_10068748": 4, "species_10068745": 5, "Q0VCR4": 5, "ENSBTAT00000019753": 2, "species_10068740": 5, "reaction_10067648": 3, "species_10067646": 4, "species_10067631": 3, "ENSBTAT00000083071": 1, "reaction_10068752": 3, "species_10067627": 5, "species_10068729": 2, "species_10068750": 6, "reaction_10068755": 4, "species_10068734": 5, "reaction_10067634": 3, "reaction_10067639": 4, "species_10067636": 4, "reaction_10067622": 4, "species_10067617": 4, "reaction_10090696": 5, "species_10090685": 3, "species_1605745": 1, "species_10090689": 3, "species_10090691": 2, "ENSBTAT00000021325": 2, "reaction_10034138": 4, "species_10034111": 5, "A0A3Q1LZJ1": 4, "ENSBTAT00000085404": 1, "species_10034135": 4, "species_10034115": 3, "ENSBTAT00000008518": 2, "reaction_10050637": 6, "species_10050635": 4, "F1MJ28": 3, "ENSBTAT00000001373": 1, "species_10034078": 3, "reaction_10034118": 3, "species_10034099": 4, "reaction_10033737": 17, "species_10033734": 2, "Q1LZA3": 2, "ENSBTAT00000079655": 1, "reaction_10078529": 5, "species_10078526": 2, "ENSBTAT00000066927": 1, "reaction_10033728": 5, "reaction_10076130": 5, "species_5691492": 2, "species_10076127": 3, "F1MUZ8": 2, "ENSBTAT00000069554": 1, "reaction_10033716": 9, "reaction_10076406": 4, "species_5693762": 2, "species_5693772": 1, "species_10076403": 3, "F1MUP1": 2, "ENSBTAT00000009723": 1, "F1MGS8": 2, "ENSBTAT00000000354": 1, "reaction_10043917": 5, "species_209793": 1, "species_10043914": 2, "ENSBTAT00000019543": 1, "reaction_10043948": 6, "species_29500": 4, "species_209911": 1, "species_10043945": 4, "F1N5Q8": 2, "ENSBTAT00000007030": 1, "E1BGX6": 2, "ENSBTAT00000027708": 1, "reaction_10033681": 5, "species_10033678": 2, "A0A452DIW8": 2, "ENSBTAT00000010309": 1, "reaction_10091773": 4, "species_10070522": 4, "species_10091771": 2, "species_10091769": 2, "reaction_10068030": 3, "species_10035394": 5, "species_10068026": 9, "species_10068028": 9, "reaction_10074240": 3, "species_10068034": 2, "species_10068032": 10, "reaction_10074254": 3, "species_10074251": 3, "reaction_10091806": 3, "species_10091797": 4, "E1B7G3": 5, "ENSBTAT00000025473": 2, "species_10091803": 3, "reaction_10091793": 5, "species_10091786": 2, "species_10091790": 2, "ENSBTAT00000045447": 1, "reaction_10091808": 4, "species_10072342": 2, "ENSBTAT00000023165": 2, "species_10045220": 4, "ENSBTAT00000026526": 2, "species_10072344": 7, "F6QH17": 6, "E1BKM4": 2, "reaction_10091779": 3, "species_10070680": 6, "species_10091777": 5, "reaction_10091810": 3, "species_10091795": 2, "reaction_10091783": 5, "species_994146": 2, "species_10070686": 5, "species_1629770": 7, "species_994141": 5, "species_10091781": 7, "reaction_10081481": 5, "species_6803725": 7, "CHEBI:85299": 1, "CHEBI:85263": 1, "CHEBI:71464": 1, "CHEBI:85262": 1, "species_6803745": 1, "species_6803778": 7, "species_10081478": 2, "F1MN16": 2, "ENSBTAT00000025945": 1, "reaction_10044540": 5, "species_264618": 7, "species_264643": 1, "species_10044537": 2, "ENSBTAT00000022369": 1, "reaction_10049090": 7, "species_264638": 5, "species_10049087": 2, "ENSBTAT00000005693": 1, "reaction_10071437": 4, "species_10071423": 3, "ENSBTAT00000071329": 2, "species_10071419": 2, "ENSBTAT00000079326": 2, "species_10071433": 3, "Q32LM6": 3, "ENSBTAT00000070192": 1, "A0A452DHU4": 3, "ENSBTAT00000001914": 1, "species_10071435": 5, "A0A3Q1MLH9": 2, "A0A3Q1LPV4": 4, "reaction_10049583": 7, "species_352003": 1, "species_352011": 4, "species_10049580": 3, "A5PJX7": 2, "ENSBTAT00000019308": 1, "E1BPI1": 2, "ENSBTAT00000038826": 1, "reaction_10052018": 3, "species_10052015": 2, "ENSBTAT00000063578": 2, "reaction_10052013": 5, "species_10052010": 3, "Q0VCA1": 3, "ENSBTAT00000009547": 1, "F1N6X2": 2, "ENSBTAT00000010598": 1, "reaction_10051999": 5, "species_10051996": 2, "reaction_10051989": 7, "species_880046": 1, "species_10051986": 2, "E1BDP3": 2, "ENSBTAT00000029203": 1, "reaction_10033755": 5, "species_113522": 1, "species_10033752": 2, "E1BHZ6": 2, "ENSBTAT00000012233": 1, "reaction_10044461": 5, "species_212615": 1, "reaction_10044076": 10, "species_10044069": 7, "F1MJN4": 2, "ENSBTAT00000025456": 1, "A6H774": 2, "ENSBTAT00000017953": 1, "P46411": 2, "ENSBTAT00000024287": 1, "F1MUT8": 2, "ENSBTAT00000016615": 1, "A0A3Q1MR13": 2, "ENSBTAT00000069455": 1, "species_10044074": 2, "ENSBTAT00000028661": 1, "reaction_10033746": 7, "species_10033743": 2, "P15103": 2, "ENSBTAT00000074216": 1, "reaction_10044086": 3, "species_10044083": 1, "reaction_10054361": 3, "species_10054358": 10, "A0A3Q1MA32": 2, "ENSBTAT00000068615": 1, "F1MHX4": 2, "ENSBTAT00000015688": 1, "Q08E50": 2, "ENSBTAT00000080524": 1, "E1BE96": 2, "ENSBTAT00000017637": 1, "P08219": 2, "ENSBTAT00000009483": 1, "P08220": 2, "ENSBTAT00000023711": 1, "E1BJH4": 2, "ENSBTAT00000060999": 1, "reaction_10054372": 3, "species_10054369": 3, "E1B988": 2, "ENSBTAT00000001857": 1, "reaction_10051085": 3, "species_10050486": 3, "species_10051083": 4, "reaction_10091067": 4, "species_10091060": 4, "species_10091064": 4, "reaction_10091075": 3, "species_10091071": 2, "ENSBTAT00000010230": 2, "species_10091073": 4, "F6RXS3": 2, "reaction_10090547": 2, "species_10090537": 3, "species_10090545": 3, "reaction_10054318": 7, "species_10054315": 7, "G3N1Q1": 2, "ENSBTAT00000062928": 1, "F1N4Y2": 4, "ENSBTAT00000014292": 1, "E1BAL4": 2, "ENSBTAT00000056946": 1, "F1N5G0": 2, "ENSBTAT00000055354": 1, "G5E5J6": 2, "ENSBTAT00000022113": 1, "reaction_10091521": 7, "species_10091518": 4, "reaction_10091525": 3, "species_10091523": 2, "reaction_10051521": 3, "species_10051518": 11, "F1MDD1": 3, "ENSBTAT00000039651": 1, "F1MF30": 5, "ENSBTAT00000039752": 1, "E1BHK0": 5, "ENSBTAT00000022855": 1, "F1MQ06": 5, "ENSBTAT00000018679": 1, "A0A3Q1MJN8": 5, "ENSBTAT00000075573": 1, "A6QPI7": 3, "ENSBTAT00000020942": 1, "Q8SPU7": 3, "ENSBTAT00000018151": 1, "F1N4T3": 5, "ENSBTAT00000002910": 1, "reaction_10051523": 3, "species_10051516": 9, "reaction_10051498": 3, "species_10051495": 8, "reaction_10051525": 3, "species_10051493": 6, "reaction_10065894": 3, "species_10065890": 2, "ENSBTAT00000070781": 2, "species_10065892": 3, "A0A3Q1M4J2": 2, "reaction_10039217": 3, "species_166005": 8, "species_10039213": 3, "ENSBTAT00000062921": 2, "species_10039215": 3, "G3N2G9": 3, "reaction_10039560": 2, "species_10039552": 4, "species_10039558": 4, "reaction_10040197": 2, "species_10040195": 3, "reaction_10085369": 3, "species_2186967": 2, "species_10085367": 3, "reaction_10081506": 3, "species_181015": 2, "species_10081504": 3, "P10103": 9, "reaction_10081510": 3, "species_10081508": 3, "reaction_10060783": 5, "species_10060771": 6, "A0A3Q1MIF7": 2, "ENSBTAT00000074388": 2, "A0A3Q1MK24": 7, "ENSBTAT00000079344": 2, "species_10060769": 3, "species_10060751": 3, "species_10060763": 3, "reaction_10060785": 2, "species_10060757": 4, "E1BBH4": 3, "ENSBTAT00000001581": 2, "species_10060781": 3, "reaction_10060773": 5, "species_10060749": 2, "reaction_10060759": 3, "species_10060755": 2, "reaction_10091739": 3, "species_10091735": 2, "species_9678628": 1, "species_10091737": 2, "reaction_10066168": 4, "species_10066165": 10, "reaction_10066059": 4, "species_10066057": 4, "reaction_10066141": 3, "species_10066131": 5, "species_10066139": 7, "reaction_10066172": 3, "species_10066124": 5, "species_10066109": 2, "species_10066170": 4, "reaction_10066127": 5, "species_10066122": 2, "reaction_10066147": 5, "species_10065638": 19, "G3N342": 4, "ENSBTAT00000065204": 1, "E1BNU1": 4, "ENSBTAT00000026773": 1, "Q9BDR7": 23, "ENSBTAT00000034054": 1, "reaction_10066180": 3, "species_10066178": 6, "reaction_10066120": 4, "species_10066117": 2, "species_10065617": 2, "reaction_10066065": 5, "species_10066061": 8, "species_10066063": 8, "reaction_10066082": 3, "species_10065484": 3, "species_10065486": 4, "reaction_10066151": 5, "species_10066149": 2, "species_10066049": 20, "reaction_10066080": 3, "species_10066076": 6, "species_10066078": 10, "reaction_10066144": 5, "reaction_10065642": 3, "species_10065640": 19, "reaction_10066094": 5, "species_10066091": 10, "F1MSH3": 5, "ENSBTAT00000046704": 1, "reaction_10066052": 5, "species_10066042": 10, "species_10066047": 11, "reaction_10066102": 4, "species_10066099": 10, "reaction_10081085": 2, "species_10081071": 67, "Q05204": 5, "ENSBTAT00000045121": 1, "A0A3Q1M4J0": 9, "ENSBTAT00000072837": 1, "A0A3Q1NMT9": 9, "ENSBTAT00000070673": 1, "F1MRG6": 9, "ENSBTAT00000012873": 1, "F1MZ44": 9, "ENSBTAT00000045380": 1, "E1BCF4": 7, "ENSBTAT00000012484": 1, "A0A3Q1MS24": 6, "ENSBTAT00000075240": 1, "P61285": 7, "ENSBTAT00000081563": 1, "A7YWC4": 5, "ENSBTAT00000012676": 1, "G3N3S2": 6, "ENSBTAT00000064122": 1, "A6QLZ0": 5, "ENSBTAT00000043753": 1, "A0A3Q1MCZ8": 5, "ENSBTAT00000067584": 1, "A0A3Q1LZT3": 7, "ENSBTAT00000069265": 1, "A0A3S5ZPJ1": 3, "ENSBTAT00000017459": 1, "F1MIW8": 3, "ENSBTAT00000018382": 1, "E1BGJ5": 9, "ENSBTAT00000005511": 1, "A0A3Q1NNM6": 7, "ENSBTAT00000081334": 1, "G5E574": 9, "ENSBTAT00000084846": 12, "G5E671": 9, "A0A3Q1NNG7": 9, "E1BFM6": 9, "E1BNM1": 9, "G3MXU0": 9, "ENSBTAT00000084657": 1, "A0A3Q1M953": 9, "A0A3Q1MX09": 9, "A0A3Q1N1V7": 9, "A0A3Q1NNA9": 9, "A0A3Q1LN32": 9, "A0A3Q1LWA7": 9, "A0A3Q1M1J2": 9, "ENSBTAT00000074686": 1, "A0A3Q1M411": 9, "Q9MYM4": 7, "A0A3Q1LWC4": 3, "ENSBTAT00000077476": 1, "E1BD53": 5, "ENSBTAT00000035679": 1, "Q2KII9": 5, "ENSBTAT00000019566": 1, "F1N0T3": 7, "ENSBTAT00000023242": 1, "F6PZJ9": 6, "ENSBTAT00000084844": 2, "A2VDP5": 3, "ENSBTAT00000004547": 1, "A2VDL2": 11, "G5E5N4": 5, "ENSBTAT00000026431": 1, "A0A3Q1LL92": 5, "ENSBTAT00000066802": 1, "A0A3Q1LVA6": 5, "ENSBTAT00000066593": 1, "E1B6Z4": 5, "ENSBTAT00000026429": 1, "E1BHT5": 7, "ENSBTAT00000020277": 1, "A5PJK0": 5, "ENSBTAT00000001458": 1, "G5E5S0": 7, "ENSBTAT00000028846": 1, "Q1RMS1": 12, "ENSBTAT00000000367": 1, "F1MHU6": 5, "ENSBTAT00000020198": 1, "A0A3Q1LMZ3": 4, "ENSBTAT00000069125": 2, "A0JN39": 7, "ENSBTAT00000008616": 1, "E1B876": 5, "ENSBTAT00000047448": 1, "Q3LUH2": 13, "ENSBTAT00000032346": 1, "A0A3Q1NBC9": 16, "ENSBTAT00000073497": 2, "A0A452DJ67": 16, "E1BDF5": 3, "ENSBTAT00000049662": 1, "F1N4H1": 9, "ENSBTAT00000055016": 1, "species_10081083": 67, "reaction_10079949": 2, "species_10079839": 66, "A7MBA7": 10, "ENSBTAT00000013758": 1, "F1MMD5": 12, "ENSBTAT00000008020": 1, "E1BA23": 6, "ENSBTAT00000021018": 1, "Q2HJ57": 5, "ENSBTAT00000021704": 1, "A0A452DI43": 5, "ENSBTAT00000008107": 1, "F1MRP0": 5, "ENSBTAT00000000876": 1, "Q5E987": 5, "ENSBTAT00000027507": 1, "P68401": 5, "ENSBTAT00000007398": 1, "Q3ZCI9": 7, "ENSBTAT00000018917": 1, "P79105": 3, "ENSBTAT00000063314": 1, "A0A3Q1MFC3": 3, "ENSBTAT00000069599": 1, "A5PKG9": 3, "ENSBTAT00000078914": 2, "Q5I2E5": 5, "ENSBTAT00000084171": 1, "Q17QP9": 5, "F1MWU9": 5, "ENSBTAT00000057500": 1, "Q2KJ46": 5, "ENSBTAT00000028608": 1, "A0A3Q1LMV5": 7, "ENSBTAT00000084460": 1, "F1MHT1": 5, "Q5E9F9": 5, "ENSBTAT00000065774": 1, "Q3SWY3": 7, "ENSBTAT00000025179": 1, "Q2KJ25": 5, "ENSBTAT00000003145": 1, "A0A452DJA8": 6, "ENSBTAT00000016346": 1, "A0A3Q1LX83": 5, "ENSBTAT00000001309": 2, "Q3T0Y5": 5, "F1MWE0": 5, "ENSBTAT00000028983": 1, "A0A3Q1MGS0": 8, "ENSBTAT00000074118": 1, "A0A140T831": 7, "ENSBTAT00000000683": 1, "P62935": 5, "ENSBTAT00000015924": 1, "A0A452DIT4": 8, "ENSBTAT00000023325": 2, "Q58DK5": 7, "ENSBTAT00000000315": 1, "P68103": 5, "A0A3Q1N1A3": 5, "ENSBTAT00000073135": 3, "A0A3Q1N4Z1": 5, "A0A3Q1NLY8": 5, "A0A452DIE3": 4, "ENSBTAT00000000841": 1, "A0A3Q1LPS7": 5, "ENSBTAT00000084564": 1, "species_10079947": 66, "reaction_10080063": 2, "species_10080039": 38, "A0A3Q1LRA9": 3, "ENSBTAT00000080425": 1, "P33046": 6, "ENSBTAT00000044788": 3, "E1BPI3": 5, "ENSBTAT00000026661": 1, "Q3ZCL0": 5, "ENSBTAT00000076131": 1, "Q2LGB5": 5, "ENSBTAT00000010835": 1, "A6QLB1": 3, "ENSBTAT00000016464": 1, "A0A3Q1M2J3": 7, "ENSBTAT00000079464": 1, "E1B8Y2": 5, "ENSBTAP00000001395": 1, "Q3ZC41": 5, "F6RMV5": 7, "ENSBTAT00000003618": 1, "E1B6Z6": 5, "ENSBTAT00000018806": 1, "F1MVJ8": 5, "ENSBTAT00000030920": 1, "F1MD23": 5, "ENSBTAT00000045994": 1, "O46675": 5, "ENSBTAT00000039536": 1, "P24627": 8, "ENSBTAT00000001704": 2, "A7YWG4": 7, "ENSBTAT00000009917": 1, "P80189": 8, "ENSBTAT00000038266": 2, "F1MW13": 3, "ENSBTAT00000009806": 1, "Q3MHQ1": 4, "ENSBTAT00000007133": 1, "A4IF76": 5, "ENSBTAT00000074688": 1, "species_10080061": 38, "reaction_10080719": 2, "species_10080687": 74, "Q29455": 5, "ENSBTAT00000070817": 1, "F1N3T5": 5, "ENSBTAT00000021761": 2, "A0A3Q1MAL1": 5, "ENSBTAT00000070277": 1, "A0A3Q1MP64": 5, "ENSBTAT00000068539": 1, "A0A3Q1M0A2": 3, "ENSBTAT00000074088": 1, "A0A3Q1LNV7": 5, "ENSBTAT00000083870": 1, "A6H797": 3, "ENSBTAT00000026715": 1, "A0A3Q1MFT3": 5, "ENSBTAT00000084806": 1, "A4IFU2": 5, "ENSBTAT00000083623": 1, "A0A3Q1N0X5": 5, "ENSBTAT00000068372": 1, "E1BFE2": 5, "ENSBTAT00000020345": 1, "F1N1F5": 3, "ENSBTAT00000021843": 1, "Q58DM3": 5, "ENSBTAT00000008479": 1, "E1BNL9": 5, "ENSBTAT00000027255": 1, "A0A3Q1M6K1": 3, "Q2KI97": 5, "ENSBTAT00000020710": 1, "A0A3Q1M4C7": 3, "A8E4P3": 7, "ENSBTAT00000052503": 1, "A0A3Q1NF89": 7, "ENSBTAT00000076616": 1, "F1MTY9": 3, "ENSBTAT00000047056": 2, "F1MN89": 3, "ENSBTAT00000008168": 1, "F1N680": 5, "ENSBTAT00000026019": 1, "F1MZS9": 4, "ENSBTAT00000035230": 1, "A0A3Q1MQ27": 8, "ENSBTAT00000069303": 2, "F1MMX5": 5, "ENSBTAT00000069044": 1, "A0A3Q1M2M7": 6, "ENSBTAT00000073921": 1, "Q32PA1": 5, "ENSBTAT00000002967": 1, "F1N3R7": 3, "ENSBTAT00000026770": 1, "A4IFF5": 5, "ENSBTAT00000026308": 1, "A0A3Q1LPK7": 12, "ENSBTAT00000075634": 2, "A0A3Q1MSR2": 12, "A0A3Q1M288": 5, "ENSBTAT00000085751": 1, "Q6QRN7": 3, "ENSBTAT00000005137": 1, "A0A3Q1LPW8": 5, "ENSBTAT00000075991": 1, "species_10080717": 74, "reaction_10079391": 2, "species_10079319": 41, "Q5W1C4": 5, "ENSBTAT00000080090": 1, "A0A3Q1MNC0": 6, "ENSBTAT00000034356": 3, "A0A3Q1NGZ9": 6, "F1MUL1": 6, "Q3MHK8": 3, "ENSBTAT00000034879": 1, "Q3ZBE7": 5, "ENSBTAT00000032525": 1, "P02070": 15, "ENSBTAT00000057323": 1, "species_10079389": 41, "reaction_10079199": 2, "species_10079131": 73, "A0A452DIB1": 3, "ENSBTAT00000013018": 1, "F1MDR7": 5, "ENSBTAT00000003865": 1, "E1BK38": 5, "ENSBTAT00000061018": 1, "P11023": 3, "ENSBTAT00000014062": 1, "F1MNI4": 3, "ENSBTAT00000018777": 1, "F1MCK4": 3, "ENSBTAT00000054453": 1, "Q673L2": 3, "ENSBTAT00000027807": 1, "Q2KI99": 13, "ENSBTAT00000071484": 3, "A0A3Q1NDL5": 5, "ENSBTAT00000086325": 1, "G3X6D0": 5, "ENSBTAT00000004058": 1, "A0A3Q1MBS7": 5, "ENSBTAT00000082349": 1, "E1BPL8": 3, "ENSBTAT00000002681": 1, "F1MIE6": 8, "ENSBTAT00000037678": 1, "F1MJS9": 4, "ENSBTAT00000013320": 2, "A0A3Q1MB09": 3, "ENSBTAT00000068383": 1, "species_10079197": 73, "reaction_10078929": 2, "species_10078881": 42, "Q2KIW2": 3, "ENSBTAT00000000146": 1, "Q3T0Q9": 3, "ENSBTAT00000015396": 1, "G3MY77": 3, "ENSBTAT00000065645": 2, "A5PJY9": 5, "ENSBTAT00000020644": 1, "A0A3Q1NHB1": 3, "ENSBTAT00000080189": 1, "Q0II86": 5, "ENSBTAT00000027666": 1, "F1MTK4": 6, "ENSBTAT00000001250": 2, "A0A3Q1MDS4": 3, "ENSBTAT00000073232": 1, "A0A3Q1MAZ1": 3, "ENSBTAT00000071382": 1, "species_10078927": 42, "reaction_10081265": 2, "species_10081245": 72, "F1MNS8": 3, "ENSBTAT00000061310": 1, "G3N0V2": 11, "ENSBTAT00000065029": 1, "Q29RY7": 3, "ENSBTAT00000012815": 1, "A4IFQ6": 3, "ENSBTAT00000018403": 1, "P07688": 3, "ENSBTAT00000036795": 1, "E1BB52": 4, "ENSBTAT00000002003": 2, "A0A452DJ01": 3, "ENSBTAT00000011678": 1, "F1MXZ0": 5, "species_10081263": 72, "reaction_10080435": 2, "species_10080307": 79, "F1MGY9": 3, "ENSBTAT00000022716": 1, "A0A3Q1MPJ7": 3, "ENSBTAT00000067144": 1, "A7MBA2": 3, "ENSBTAT00000006754": 1, "A6QPT4": 5, "ENSBTAT00000067752": 1, "O77834": 4, "ENSBTAT00000006383": 1, "A0A3Q1LYV0": 3, "ENSBTAT00000070714": 1, "A6QLB7": 3, "ENSBTAT00000017775": 1, "Q3ZBH5": 3, "ENSBTAT00000013796": 1, "Q3MHM5": 3, "ENSBTAT00000074704": 1, "A0A3Q1LUG9": 3, "ENSBTAT00000076880": 1, "O46415": 4, "ENSBTAT00000009965": 1, "F1N7I6": 3, "ENSBTAT00000024550": 1, "F1N1V6": 3, "ENSBTAT00000005121": 1, "F1MU24": 3, "ENSBTAT00000006069": 1, "Q2KJD0": 3, "ENSBTAT00000009158": 1, "A0A3Q1LQA6": 3, "ENSBTAT00000072426": 1, "E1BFP1": 3, "ENSBTAT00000000304": 1, "G3MXK8": 5, "ENSBTAT00000064845": 2, "A6QQ81": 3, "ENSBTAT00000034528": 1, "A0A452DJ87": 3, "ENSBTAT00000039203": 1, "A6QNX2": 3, "ENSBTAT00000064726": 1, "A0A3Q1NEU9": 3, "ENSBTAT00000066561": 1, "A0A3Q1LKA9": 3, "ENSBTAT00000084208": 1, "A0A3Q1ML33": 3, "ENSBTAT00000073654": 1, "A0A3Q1LMW6": 3, "ENSBTAT00000073103": 1, "E1B8B5": 3, "ENSBTAT00000053165": 1, "A0A3Q1LTS9": 3, "ENSBTAT00000068563": 1, "F1MMS7": 3, "ENSBTAT00000065330": 1, "A0A3Q1LY36": 3, "ENSBTAT00000068245": 1, "G3X8C3": 3, "ENSBTAT00000055709": 1, "A0A3Q1LIW8": 6, "ENSBTAT00000073870": 1, "P79345": 4, "ENSBTAT00000029271": 2, "F1MUP9": 3, "ENSBTAT00000009715": 1, "F1MGC2": 3, "ENSBTAT00000036230": 1, "G3N2H4": 3, "ENSBTAT00000063121": 1, "F6QIT9": 3, "ENSBTAT00000019270": 1, "P04272": 4, "ENSBTAT00000012655": 1, "A0A3Q1MS42": 3, "ENSBTAT00000074408": 1, "A0A3Q1LGT8": 5, "ENSBTAT00000083141": 1, "E1BKA1": 5, "ENSBTAT00000046857": 1, "Q28050": 5, "ENSBTAT00000010838": 1, "species_10080433": 79, "reaction_10079653": 2, "species_10079613": 77, "Q32LK2": 3, "ENSBTAT00000022077": 1, "species_10079651": 77, "reaction_10072392": 3, "species_10072358": 5, "CHEBI:28808": 6, "species_10072390": 6, "reaction_10072395": 4, "species_10072360": 6, "reaction_10084636": 3, "species_10084632": 8, "species_10084616": 2, "ENSBTAT00000054378": 2, "species_10084634": 9, "E1BJL5": 2, "reaction_10072364": 3, "species_10072362": 7, "species_10072008": 4, "reaction_10072383": 5, "species_10072378": 4, "species_10072380": 3, "reaction_10072388": 4, "species_10072385": 6, "reaction_10072374": 3, "species_10072370": 3, "species_5621138": 2, "species_10072372": 4, "reaction_10072057": 3, "species_10072055": 2, "ENSBTAT00000074019": 4, "species_10071996": 3, "species_10071998": 3, "A0A3Q1LKU2": 6, "reaction_10072011": 5, "reaction_10072045": 5, "species_10072038": 3, "CHEBI:37671": 2, "F1N2F3": 3, "ENSBTAT00000085840": 1, "species_10072043": 3, "reaction_10072061": 2, "species_10072059": 2, "reaction_10072015": 3, "species_10072000": 4, "species_10072013": 3, "reaction_10072032": 2, "species_10072004": 4, "species_10072019": 4, "reaction_10072002": 3, "reaction_10072053": 3, "species_10072049": 4, "species_10072051": 4, "reaction_10072006": 3, "species_10070610": 2, "reaction_10072022": 5, "species_10072017": 2, "reaction_10054649": 3, "species_10054645": 5, "A0A3Q1N570": 3, "ENSBTAT00000073079": 2, "species_10054492": 4, "A0A3Q1MF14": 3, "ENSBTAT00000076236": 3, "species_10054647": 6, "reaction_10054494": 3, "species_10054490": 2, "species_10054488": 2, "reaction_10066238": 3, "species_10039322": 5, "species_10066236": 3, "reaction_10090400": 2, "species_10084018": 21, "Q2KIV9": 7, "ENSBTAT00000014871": 1, "A0A3B0IZF8": 7, "ENSBTAT00000014865": 1, "Q5E9E3": 7, "ENSBTAT00000040146": 1, "A0A3Q1MGP1": 6, "ENSBTAT00000073935": 1, "species_10084063": 20, "reaction_10055971": 3, "species_1006146": 3, "species_10054484": 3, "A0A3Q1LSC6": 3, "ENSBTAT00000069343": 1, "F1MC45": 3, "ENSBTAT00000029340": 1, "species_10055969": 5, "reaction_10087797": 3, "species_10054643": 4, "species_10054624": 3, "reaction_10084020": 3, "species_10039462": 21, "reaction_10054678": 5, "species_10054675": 3, "species_10054657": 3, "reaction_10039465": 4, "species_10039302": 3, "species_10039310": 3, "reaction_10039778": 3, "species_10039759": 19, "species_10039765": 20, "species_10039776": 7, "C4T8B4": 2, "ENSBTAT00000018469": 1, "species_1524071": 3, "reaction_10039782": 2, "reaction_10054736": 3, "species_983438": 2, "reaction_10053134": 3, "species_10053126": 3, "ENSBTAT00000085261": 2, "species_10053130": 2, "ENSBTAT00000016601": 2, "species_10053132": 3, "F1MUU5": 2, "A0A3Q1MIH6": 3, "reaction_10053122": 3, "species_10053118": 4, "species_10053120": 5, "reaction_10053095": 3, "species_10053091": 2, "species_10053086": 3, "species_10053093": 3, "reaction_10056088": 3, "species_10056080": 4, "species_10053054": 5, "species_10056086": 5, "reaction_10053058": 3, "species_10053056": 4, "reaction_10092318": 3, "species_10070254": 2, "species_10092316": 3, "reaction_10056090": 4, "species_10039556": 5, "species_10056078": 4, "reaction_10056082": 6, "species_10040189": 4, "reaction_10056084": 3, "species_10056076": 4, "reaction_10066559": 3, "species_10066555": 2, "ENSBTAT00000008082": 2, "species_3134861": 1, "species_10066557": 2, "Q05B79": 2, "reaction_10090837": 2, "reaction_10066536": 4, "species_10061500": 4, "Q0VCP5": 2, "ENSBTAT00000022801": 2, "species_10066530": 3, "species_10055114": 3, "reaction_10061502": 3, "species_10061498": 3, "reaction_10066551": 4, "species_10054900": 2, "species_10066540": 3, "ENSBTAT00000043510": 2, "species_10066548": 3, "A3KN07": 3, "reaction_10066608": 3, "species_874088": 2, "species_10066604": 2, "ENSBTAT00000011748": 3, "species_10066606": 3, "E1BIN9": 35, "reaction_10065388": 2, "species_10039546": 3, "reaction_10063376": 2, "reaction_10067225": 2, "species_10067208": 3, "species_10067210": 3, "reaction_10067229": 4, "species_10046560": 2, "species_10065393": 2, "species_10067227": 5, "E1BKP4": 6, "reaction_10067231": 4, "species_10067220": 3, "reaction_10067233": 4, "species_10067218": 5, "reaction_10067216": 2, "species_10067214": 2, "reaction_10067223": 5, "species_10065404": 4, "reaction_10065402": 4, "species_10065395": 4, "species_10065400": 5, "reaction_10065407": 5, "reaction_10066880": 3, "species_3244587": 2, "species_10065409": 4, "species_10066878": 3, "reaction_10090019": 3, "species_8982080": 3, "species_2395973": 4, "CHEBI:47037": 2, "species_10090017": 4, "reaction_10065413": 3, "species_10065411": 3, "reaction_10066532": 3, "reaction_10081432": 3, "species_10081428": 5, "P08904": 4, "ENSBTAT00000011585": 1, "G3MZA1": 4, "ENSBTAT00000065979": 1, "species_6803074": 4, "CHEBI:55478": 2, "species_6789198": 10, "species_10081430": 7, "reaction_10082008": 2, "species_10081939": 3, "ENSBTAT00000083501": 3, "species_10082006": 3, "reaction_10056539": 3, "species_10056535": 3, "species_8879165": 4, "species_10056537": 2, "reaction_10082012": 3, "species_8931784": 8, "species_10082010": 3, "A0A3Q1LWA5": 3, "reaction_10083100": 3, "species_10083096": 2, "ENSBTAT00000025186": 2, "species_10083098": 3, "Q95JC3": 2, "reaction_10070906": 3, "species_10070902": 3, "CHEBI:17189": 2, "species_912516": 3, "species_10070904": 4, "species_917966": 9, "reaction_10056416": 4, "species_2101051": 2, "species_10056412": 2, "species_1222611": 1, "species_10056414": 4, "reaction_10078759": 3, "species_10078755": 5, "species_10078757": 6, "reaction_10082004": 3, "species_10081994": 2, "ENSBTAT00000077381": 2, "species_10082002": 3, "A0A3Q1LX31": 2, "reaction_10081559": 3, "species_10081555": 3, "G3N3R4": 3, "ENSBTAT00000064812": 1, "species_6804535": 4, "CHEBI:42976": 2, "CHEBI:59496": 2, "CHEBI:85986": 2, "species_10081557": 6, "reaction_10081943": 3, "species_10081941": 3, "reaction_10082967": 3, "species_10082963": 4, "A0A3Q1ME64": 3, "ENSBTAT00000078640": 1, "species_10082965": 4, "reaction_10084683": 3, "species_10079373": 2, "species_10084681": 4, "reaction_10080842": 7, "species_10080839": 4, "E1BH94": 3, "ENSBTAT00000047024": 1, "species_10080837": 4, "species_6799970": 3, "CHEBI:28881": 1, "species_6799975": 1, "reaction_10080844": 3, "reaction_10084686": 4, "species_6788991": 3, "CHEBI:21615": 1, "species_6788982": 1, "reaction_10058388": 2, "species_10058328": 18, "species_10058386": 18, "reaction_10081410": 3, "species_10081389": 4, "ENSBTAT00000086119": 4, "species_10081408": 3, "P23132": 4, "reaction_10082183": 3, "species_10082179": 5, "F1MLW2": 3, "ENSBTAT00000020875": 1, "F1MHQ2": 3, "ENSBTAT00000012052": 1, "F6RMF1": 3, "ENSBTAT00000044454": 1, "species_10082181": 5, "reaction_10081404": 4, "species_10081399": 2, "species_10081401": 2, "species_10058556": 2, "reaction_10080831": 4, "species_10080827": 2, "A0A3Q1M1U5": 3, "ENSBTAT00000078335": 1, "species_10080829": 3, "reaction_10081406": 3, "species_10081391": 4, "reaction_10087601": 3, "species_10087599": 5, "reaction_10081397": 3, "species_10081395": 3, "reaction_10081385": 3, "species_10081382": 2, "species_10080371": 2, "reaction_10082977": 3, "species_6803081": 1, "species_10082971": 2, "ENSBTAT00000056512": 2, "species_10082975": 3, "A1A4Q6": 2, "reaction_10083106": 3, "species_10083102": 4, "species_10083104": 4, "reaction_10084706": 3, "species_10059808": 3, "species_10084704": 4, "reaction_10051836": 3, "species_10051824": 2, "A0A3Q1M2Q8": 3, "ENSBTAT00000085633": 1, "species_10051832": 2, "A0A3Q1N8Q0": 3, "ENSBTAT00000066698": 1, "species_10051834": 3, "reaction_10077919": 6, "species_1222719": 3, "species_6788973": 2, "species_1470067": 5, "species_1222475": 3, "species_6789150": 2, "species_10077916": 4, "CHEBI:55376": 3, "reaction_10084322": 5, "species_8855492": 1, "species_8855489": 1, "species_10084319": 3, "P80025": 2, "ENSBTAT00000016986": 1, "reaction_10086405": 6, "species_6789221": 1, "species_8933637": 1, "species_10077914": 5, "reaction_10077924": 6, "reaction_10077926": 3, "reaction_10077921": 6, "species_1222561": 1, "species_1222461": 1, "reaction_10077904": 3, "species_10077901": 2, "reaction_10047907": 7, "species_202124": 1, "species_10047904": 2, "ENSBTAT00000069366": 1, "reaction_10056531": 3, "species_10056528": 20, "Q28029": 10, "ENSBTAT00000009961": 1, "P79251": 10, "ENSBTAT00000000240": 1, "Q0VCV6": 10, "ENSBTAT00000019267": 1, "E1BMV6": 10, "ENSBTAT00000026498": 1, "P31408": 10, "ENSBTAT00000024812": 1, "A0A3Q1M3I3": 10, "ENSBTAT00000073116": 1, "Q32LB7": 10, "ENSBTAT00000018250": 1, "P21282": 10, "ENSBTAT00000017968": 1, "A4IFJ9": 10, "ENSBTAT00000032875": 1, "P81103": 10, "ENSBTAT00000020094": 1, "A0A452DI38": 10, "ENSBTAT00000007912": 1, "O97681": 2, "ENSBTAT00000009563": 1, "E1BGJ7": 2, "ENSBTAT00000005588": 1, "reaction_10063368": 5, "species_1602448": 4, "species_10063365": 2, "reaction_10049304": 3, "species_10043043": 3, "ENSBTAT00000082561": 4, "species_10044490": 4, "A0A3Q1MRM3": 4, "ENSBTAT00000075471": 1, "A0A3Q1M8K4": 4, "ENSBTAT00000085126": 1, "species_10049302": 4, "A0A3Q1MRS3": 2, "reaction_10075165": 3, "species_10075149": 4, "G3N153": 5, "ENSBTAT00000065898": 1, "E1B8J2": 4, "ENSBTAT00000053203": 2, "species_10075161": 3, "Q32PI0": 4, "ENSBTAT00000011384": 1, "F1N7Q0": 4, "ENSBTAT00000005923": 1, "species_10075163": 6, "reaction_10075151": 3, "species_10075143": 2, "species_10075139": 2, "reaction_10050458": 2, "species_10050452": 2, "A2VE67": 3, "ENSBTAT00000023167": 1, "species_10050456": 2, "reaction_10040857": 2, "species_10040855": 2, "P18246": 8, "ENSBTAT00000002398": 2, "species_10040800": 3, "reaction_10040842": 3, "species_10040840": 4, "reaction_10036729": 3, "species_10036724": 2, "F1MUX1": 4, "ENSBTAT00000028844": 1, "species_10036726": 3, "species_29554": 4, "reaction_10036716": 3, "species_10036713": 2, "species_29692": 4, "reaction_10036767": 3, "species_10036764": 2, "F1MPV2": 4, "ENSBTAT00000010226": 3, "species_10036757": 3, "species_5636006": 1, "reaction_10036736": 3, "species_10036733": 2, "reaction_10036709": 3, "species_10036702": 2, "reaction_10036743": 3, "species_10036740": 2, "species_110233": 1, "reaction_10089640": 5, "species_10089633": 3, "E1B9S8": 19, "ENSBTAT00000021434": 2, "A0A3Q1MKY5": 7, "ENSBTAT00000066565": 5, "species_10086640": 4, "species_113541": 5, "species_10089637": 2, "ENSBTAT00000012404": 1, "reaction_10086716": 3, "species_10086213": 3, "species_10086712": 8, "species_10086714": 7, "reaction_10089679": 4, "species_10089672": 4, "species_10055082": 3, "species_10089674": 2, "reaction_10089681": 3, "species_10089668": 2, "reaction_10086724": 4, "species_10086719": 2, "reaction_10089610": 5, "species_10089605": 3, "species_10089607": 3, "reaction_10089357": 3, "species_10089353": 2, "ENSBTAT00000084141": 2, "species_10089355": 3, "A0A3Q1MN22": 2, "reaction_10074877": 3, "species_10055523": 3, "ENSBTAT00000020012": 2, "species_10074873": 2, "ENSBTAT00000013145": 2, "species_10074875": 3, "A0A452DJ33": 2, "F1MW99": 4, "reaction_10065177": 3, "species_10064869": 6, "E1BMZ9": 8, "ENSBTAT00000007705": 1, "F1MPS0": 6, "ENSBTAT00000039478": 1, "F1N535": 6, "ENSBTAT00000021476": 1, "F1MY41": 8, "ENSBTAT00000011562": 1, "species_10064891": 3, "species_10065175": 7, "reaction_10064904": 7, "species_10064897": 4, "species_10064901": 4, "reaction_10065563": 4, "species_10065559": 2, "ENSBTAT00000068774": 2, "species_10050283": 4, "Q2TBR3": 4, "ENSBTAT00000027913": 1, "A0A3Q1MQB1": 4, "ENSBTAT00000030281": 1, "species_10065561": 8, "A0A3Q1M8A5": 2, "reaction_10065201": 4, "species_10065186": 7, "species_10065198": 7, "reaction_10064733": 5, "species_10064715": 3, "A0A3Q1NDP8": 3, "ENSBTAT00000075206": 2, "A0A3Q1M3X4": 3, "species_10064723": 3, "species_10064730": 3, "ENSBTAT00000022950": 1, "reaction_10065572": 5, "species_10065567": 2, "ENSBTAT00000009379": 2, "species_10065570": 2, "reaction_10066345": 4, "species_10066322": 4, "F1MM88": 4, "ENSBTAT00000022098": 1, "A6H7J4": 4, "ENSBTAT00000070292": 1, "species_10066342": 3, "reaction_10066324": 3, "species_10066309": 2, "species_10066320": 2, "reaction_10070705": 5, "species_5221122": 1, "species_5221124": 1, "species_10069478": 3, "reaction_10069491": 5, "species_10069470": 2, "species_10069488": 3, "Q1RMV9": 2, "ENSBTAT00000025896": 1, "Q3ZBP2": 2, "ENSBTAT00000046962": 1, "reaction_10065095": 4, "species_10065087": 5, "species_10065092": 5, "reaction_10038371": 5, "species_159447": 2, "species_159564": 1, "species_10038368": 3, "A0A3Q1MBJ0": 2, "ENSBTAT00000077055": 1, "reaction_10038354": 7, "species_159446": 1, "species_159448": 6, "species_10038351": 3, "ENSBTAT00000025874": 2, "reaction_10039520": 3, "species_10037233": 4, "species_10037620": 4, "Q17QH5": 5, "reaction_10037237": 2, "reaction_10037622": 3, "reaction_10047809": 3, "reaction_10058908": 5, "species_426755": 7, "species_1500604": 4, "reaction_10077777": 5, "species_1602447": 2, "species_10077774": 3, "A0A3Q1MMR4": 2, "ENSBTAT00000085985": 1, "F1MSS2": 2, "ENSBTAT00000017473": 1, "reaction_10058896": 5, "species_10058855": 6, "reaction_10058834": 5, "species_1500580": 3, "species_10058831": 2, "ENSBTAT00000006476": 2, "reaction_10059860": 5, "reaction_10088649": 6, "species_189422": 1, "species_8954401": 1, "species_10088630": 2, "E1BE10": 2, "ENSBTAT00000010531": 1, "species_10088647": 3, "F1MNB3": 2, "ENSBTAT00000043938": 1, "Q1JPG0": 2, "ENSBTAT00000014090": 1, "reaction_10086248": 5, "species_8878780": 1, "species_10086245": 4, "F1N2M5": 2, "ENSBTAT00000043359": 1, "reaction_10058923": 5, "species_10058920": 2, "ENSBTAT00000015359": 1, "reaction_10035786": 5, "species_10035783": 9, "Q95JH2": 2, "ENSBTAT00000083979": 2, "A6H7D4": 2, "ENSBTAT00000007532": 2, "A0A3Q1LJ33": 2, "ENSBTAT00000076188": 2, "G5E5P6": 2, "E1BGF8": 2, "ENSBTAT00000023396": 1, "A0A3S5ZPU2": 2, "reaction_10058858": 5, "species_1524103": 1, "reaction_10059114": 5, "species_10059111": 3, "reaction_10051264": 5, "species_10035769": 2, "reaction_10035812": 6, "species_10035809": 3, "A0A452DJJ3": 2, "ENSBTAT00000021683": 1, "A0A3Q1MUU4": 2, "ENSBTAT00000057343": 1, "reaction_10044235": 8, "species_30321": 2, "species_213144": 2, "species_10044177": 5, "A0A3Q1LZ03": 6, "ENSBTAT00000067793": 1, "G3X6I4": 9, "ENSBTAT00000016177": 2, "Q29RV2": 6, "Q3T047": 6, "ENSBTAT00000063483": 1, "reaction_10044255": 8, "species_216547": 1, "species_216598": 1, "species_10044252": 2, "F1MXW1": 2, "ENSBTAT00000023544": 1, "reaction_10044158": 8, "species_215584": 2, "species_10044155": 2, "ENSBTAT00000024282": 1, "reaction_10044242": 8, "species_216620": 1, "species_10044239": 2, "reaction_10044247": 8, "species_216621": 1, "species_216612": 1, "species_10044244": 2, "reaction_10078408": 2, "species_10066675": 4, "species_10078406": 2, "reaction_10033535": 5, "species_10033519": 6, "species_10033524": 13, "species_10033532": 3, "ENSBTAT00000006518": 3, "reaction_10076341": 5, "species_10066677": 11, "reaction_10081470": 3, "species_10081466": 2, "ENSBTAT00000070196": 2, "species_10081468": 3, "A0A3Q1M6W9": 2, "reaction_10057800": 3, "species_10057796": 5, "Q5E9Y0": 6, "ENSBTAT00000005252": 1, "species_10056559": 6, "A0A3Q1MKK9": 7, "ENSBTAT00000076561": 2, "Q17QZ4": 10, "ENSBTAT00000084839": 2, "A0A3Q1M1Y7": 6, "ENSBTAT00000084739": 3, "F1MBE6": 6, "ENSBTAT00000015999": 1, "species_10057798": 6, "reaction_10057804": 3, "species_10056543": 2, "species_10057802": 3, "reaction_10057808": 3, "species_10056608": 6, "E1BMR3": 4, "ENSBTAT00000015333": 3, "species_10057806": 6, "reaction_10057812": 3, "species_10056606": 2, "species_10057810": 3, "reaction_10037433": 5, "species_10037427": 7, "species_10037431": 7, "species_10037342": 5, "reaction_10037353": 5, "species_10037346": 3, "species_10037350": 3, "reaction_10047880": 3, "species_10047872": 3, "species_10047878": 3, "reaction_10092299": 4, "species_10092295": 2, "species_10092297": 2, "reaction_10037580": 4, "species_10037563": 3, "species_10037569": 3, "reaction_10047886": 2, "species_10047884": 5, "reaction_10041337": 8, "species_193785": 2, "species_193747": 1, "species_10041101": 14, "ENSBTAT00000017935": 1, "reaction_10041339": 8, "species_193708": 2, "species_193716": 2, "reaction_10041341": 8, "species_193762": 2, "species_193741": 2, "species_10041314": 5, "reaction_10041343": 3, "species_193732": 2, "reaction_10041361": 6, "species_193707": 2, "species_193728": 1, "species_10041167": 7, "reaction_10041363": 8, "species_193777": 1, "species_193782": 2, "reaction_10041365": 6, "species_192189": 2, "species_193724": 2, "species_10041201": 4, "ENSBTAT00000003028": 1, "reaction_10041367": 8, "species_193720": 1, "reaction_10041335": 8, "species_193778": 2, "species_193739": 2, "species_10038344": 6, "ENSBTAT00000020170": 1, "reaction_10041193": 8, "species_193384": 5, "species_10041190": 2, "ENSBTAT00000068208": 1, "reaction_10041353": 6, "species_193760": 2, "species_213285": 1, "reaction_10041355": 3, "species_193793": 1, "species_193422": 1, "reaction_10041357": 8, "reaction_10041359": 8, "reaction_10041217": 8, "species_10041214": 2, "ENSBTAT00000004736": 1, "reaction_10041345": 8, "species_193757": 1, "reaction_10041347": 8, "reaction_10041349": 6, "species_10041108": 7, "ENSBTAT00000002172": 1, "reaction_10041351": 6, "species_193745": 1, "reaction_10047659": 4, "species_10047616": 14, "Q5E9H3": 6, "ENSBTAT00000003828": 2, "E1BFR4": 9, "ENSBTAT00000030589": 1, "F1N2P7": 9, "ENSBTAT00000019327": 1, "F1MIH8": 9, "ENSBTAT00000001558": 1, "F1N173": 9, "ENSBTAT00000030185": 1, "F1MEW1": 9, "ENSBTAT00000080859": 1, "species_10047656": 14, "reaction_10047763": 5, "reaction_10047618": 4, "species_10047612": 4, "species_10047592": 10, "species_10047614": 4, "reaction_10047753": 5, "species_10047714": 14, "Q02399": 5, "ENSBTAT00000010212": 1, "Q28199": 5, "ENSBTAT00000056064": 1, "A8E641": 5, "ENSBTAT00000085592": 1, "E1BER6": 5, "ENSBTAT00000005625": 1, "A2VDS7": 5, "ENSBTAT00000023643": 1, "species_10047750": 13, "reaction_10047717": 5, "species_10047695": 10, "species_10047675": 5, "reaction_10047735": 6, "species_10047586": 9, "species_10047732": 12, "species_10043848": 2, "reaction_10045244": 3, "species_10045232": 3, "ENSBTAT00000083792": 2, "species_10045240": 2, "ENSBTAT00000015162": 2, "species_10045242": 3, "E1BPB4": 2, "A0A3Q1LQU8": 3, "reaction_10045236": 3, "species_10045228": 2, "species_10045234": 3, "reaction_10089713": 3, "species_10089709": 2, "species_2299699": 4, "species_10089711": 3, "reaction_10090179": 3, "species_10043663": 3, "ENSBTAT00000061264": 2, "species_10090177": 3, "F1N739": 8, "reaction_10045517": 3, "species_10043669": 5, "species_10045513": 2, "ENSBTAT00000080797": 4, "species_10045515": 5, "A0A3Q1LI98": 3, "reaction_10049024": 4, "species_10049021": 4, "reaction_10089397": 3, "species_10089393": 3, "species_10089395": 5, "reaction_10048935": 3, "species_10048931": 3, "CHEBI:17421": 2, "species_10043667": 3, "species_10048933": 4, "reaction_10043671": 3, "reaction_10048951": 3, "species_10048947": 5, "F1N214": 3, "ENSBTAT00000021544": 1, "species_10048949": 5, "reaction_10047449": 3, "species_10047443": 8, "species_10047447": 10, "reaction_10047455": 3, "species_10047453": 11, "reaction_10047458": 5, "reaction_10045509": 2, "species_10045505": 2, "ENSBTAT00000082055": 2, "species_10045507": 2, "A0A3Q1MBH9": 2, "reaction_10045224": 3, "species_10045216": 2, "species_10045222": 3, "reaction_10069192": 3, "species_10069057": 9, "A0A3Q1LXH4": 21, "ENSBTAT00000086732": 1, "F1N0M5": 21, "ENSBTAT00000035350": 1, "F1ML02": 24, "ENSBTAT00000006988": 1, "E1BIE4": 24, "ENSBTAT00000037233": 1, "F1MII5": 24, "ENSBTAT00000020455": 1, "F1N3R6": 24, "ENSBTAT00000026780": 1, "species_10069161": 3, "species_10069190": 9, "reaction_10069226": 5, "species_10049739": 2, "ENSBTAT00000021328": 2, "species_10049762": 2, "species_10069218": 15, "A0A3Q1M7Q3": 4, "ENSBTAT00000073530": 2, "reaction_10069418": 3, "species_10069416": 8, "reaction_10069221": 4, "species_10069208": 14, "reaction_10069188": 3, "species_10069184": 2, "species_10069179": 11, "species_10069186": 11, "reaction_10069223": 3, "species_10045210": 2, "species_10069177": 9, "reaction_10069243": 3, "species_10068993": 6, "species_10069023": 8, "species_10069025": 13, "reaction_10069131": 3, "species_10069127": 20, "species_10069129": 20, "species_10069061": 20, "reaction_10069285": 4, "species_10069263": 5, "species_10069283": 5, "species_10069273": 5, "reaction_10069157": 4, "species_10069152": 25, "species_10069154": 24, "reaction_10069159": 3, "species_10069150": 23, "species_10048073": 2, "reaction_10069194": 3, "species_10069055": 5, "species_10069037": 3, "reaction_10069146": 2, "reaction_10069121": 4, "species_10069118": 19, "reaction_10069144": 5, "species_10069141": 10, "reaction_10069435": 4, "species_10069428": 9, "species_10069432": 9, "reaction_10069148": 3, "species_10069139": 8, "species_10069135": 2, "reaction_10091007": 2, "species_10090998": 2, "ENSBTAT00000079895": 2, "species_10091004": 4, "A0A3Q1MTZ4": 2, "reaction_10091009": 2, "reaction_10074603": 3, "species_10074599": 2, "ENSBTAT00000025189": 2, "species_10074595": 4, "A0A3Q1NF99": 6, "ENSBTAT00000081521": 1, "A0A3Q1MVZ5": 6, "ENSBTAT00000071985": 1, "A0A3Q1MPN5": 3, "ENSBTAT00000077549": 1, "species_10074601": 5, "A6QLD0": 2, "reaction_10074641": 3, "species_10074609": 4, "species_10074637": 2, "ENSBTAT00000006011": 2, "species_10074639": 4, "E1BFY8": 2, "reaction_10074613": 3, "species_10074607": 2, "ENSBTAT00000023124": 2, "species_10074611": 4, "F1MZT1": 2, "reaction_10081915": 2, "species_10081911": 40, "A0A3Q1LZF2": 9, "ENSBTAT00000074051": 1, "A0A3Q1M139": 9, "ENSBTAT00000087011": 1, "F1MI98": 9, "ENSBTAT00000006440": 1, "Q148I8": 9, "ENSBTAT00000018185": 1, "A0A3Q1MPF8": 9, "ENSBTAT00000072411": 1, "A6QP90": 9, "ENSBTAT00000013107": 1, "A0A3Q1LV22": 9, "ENSBTAT00000076314": 1, "F1N3T1": 9, "ENSBTAT00000026752": 1, "A7YWM2": 9, "ENSBTAT00000023156": 1, "Q0P5J4": 9, "ENSBTAT00000043116": 1, "A6H712": 9, "ENSBTAT00000043126": 1, "A0A3Q1M4F4": 9, "ENSBTAT00000071728": 1, "F6S1Q0": 9, "ENSBTAT00000001988": 1, "A0A3Q1LJB2": 9, "ENSBTAT00000083663": 1, "P08728": 9, "ENSBTAT00000006450": 1, "G3X7W8": 9, "ENSBTAT00000047914": 1, "F1MFW9": 9, "ENSBTAT00000027749": 1, "G3MX98": 9, "ENSBTAT00000064531": 1, "Q17QL7": 9, "ENSBTAT00000006445": 1, "A3KMY1": 9, "ENSBTAT00000009403": 1, "F1N362": 9, "ENSBTAT00000021519": 1, "A0A3Q1M0W3": 9, "ENSBTAT00000077014": 1, "A0A452DI61": 9, "ENSBTAT00000008857": 1, "E1B898": 9, "ENSBTAT00000018307": 1, "F1N566": 9, "ENSBTAT00000038457": 1, "Q148H4": 9, "ENSBTAT00000038458": 1, "A6QP32": 9, "ENSBTAT00000038471": 1, "Q148H8": 9, "ENSBTAT00000010391": 1, "A7YWK3": 9, "ENSBTAT00000010393": 1, "A4IFP2": 9, "ENSBTAT00000016832": 1, "A0A3Q1MDN1": 9, "ENSBTAT00000067366": 1, "F1MKE7": 9, "ENSBTAT00000057443": 1, "A6QNX5": 9, "ENSBTAT00000000815": 1, "G3MZ71": 9, "ENSBTAT00000063931": 1, "A0A452DIJ6": 9, "ENSBTAT00000016839": 1, "A0A3Q1MYR8": 9, "ENSBTAT00000072474": 1, "F1MUY2": 9, "ENSBTAT00000046815": 1, "M0QVY0": 9, "ENSBTAT00000000396": 1, "species_10081913": 41, "reaction_10081917": 2, "species_10081859": 41, "species_10081909": 40, "reaction_10081857": 3, "species_10081853": 21, "species_10081739": 20, "species_10081855": 41, "reaction_10081921": 2, "species_10081919": 41, "reaction_10081861": 2, "reaction_10082871": 3, "species_10082865": 50, "G3MYE1": 3, "ENSBTAT00000064142": 1, "G3MX57": 3, "ENSBTAT00000065975": 1, "Q24JX9": 3, "ENSBTAT00000064111": 1, "Q05B46": 3, "ENSBTAT00000049339": 1, "G3MWP0": 3, "ENSBTAT00000063461": 1, "G3N2U6": 3, "ENSBTAT00000064310": 1, "Q05B44": 3, "ENSBTAT00000024766": 1, "A0A3Q1M8D5": 3, "ENSBTAP00000066373": 1, "E1B9G9": 3, "ENSBTAP00000053063": 1, "A0A3Q1LRY2": 3, "ENSBTAT00000071483": 1, "A0A3Q1N0M4": 3, "ENSBTAT00000069096": 1, "A0A3Q1LY72": 3, "ENSBTAT00000083666": 2, "A0A3Q1N1L4": 3, "ENSBTAT00000084386": 2, "A0A3Q1M0F6": 3, "E1BAH7": 3, "A0A3Q1MWC2": 3, "ENSBTAT00000068881": 1, "F1N3V7": 3, "ENSBTAT00000043153": 1, "A0A3Q1LK19": 3, "ENSBTAT00000087153": 4, "A0A3Q1MEE6": 3, "A0A3Q1LNZ0": 3, "A6QP35": 3, "ENSBTAT00000043652": 1, "A0A3Q1LUM3": 3, "ENSBTAT00000068312": 1, "F6RZX2": 3, "ENSBTAT00000043662": 1, "A0A3Q1LYD7": 3, "A0A3Q1LUR9": 3, "ENSBTAT00000071394": 1, "G3N073": 3, "ENSBTAT00000063306": 1, "A0A3Q1LPJ2": 3, "ENSBTAT00000084954": 1, "A0A3Q1MLT3": 3, "ENSBTAT00000085549": 1, "A7YWJ9": 3, "ENSBTAT00000043142": 1, "E1BIW5": 3, "ENSBTAT00000034860": 1, "A0A3Q1MFR3": 3, "ENSBTAT00000075891": 1, "A0A3Q1NF50": 3, "ENSBTAT00000082065": 1, "A0A3Q1MN32": 3, "ENSBTAT00000084052": 5, "A7E345": 3, "ENSBTAT00000043148": 1, "A0A3Q1LFA4": 3, "A0A3Q1N1W4": 3, "E1BMY6": 3, "ENSBTAT00000043146": 1, "A0A3Q1LQD4": 3, "A0A3Q1N892": 3, "E1BMY7": 3, "ENSBTAT00000043145": 1, "A0A3Q1M5Z5": 3, "ENSBTAT00000078641": 1, "A0A3Q1LSL9": 3, "ENSBTAT00000080742": 1, "A0A3Q1NHC3": 3, "ENSBTAT00000072065": 1, "A0A3Q1N3D2": 3, "ENSBTAT00000082261": 1, "Q0VC31": 3, "ENSBTAT00000065867": 1, "A5PJJ0": 3, "ENSBTAT00000056985": 1, "A5PJJ4": 3, "ENSBTAT00000056308": 1, "F1MTA9": 3, "ENSBTAP00000021000": 1, "A0A3Q1N0A2": 3, "ENSBTAT00000075298": 1, "species_10082869": 89, "reaction_10050085": 5, "species_10050064": 2, "A0A3Q1NNL3": 5, "ENSBTAT00000079928": 1, "species_10050074": 4, "A0A3Q1LJZ7": 3, "ENSBTAT00000073649": 1, "species_10050082": 5, "reaction_10050116": 3, "species_10050080": 2, "species_10050112": 4, "P17667": 3, "ENSBTAT00000038612": 1, "Q7YS81": 3, "ENSBTAT00000007923": 1, "A0A3Q1LQN2": 3, "ENSBTAT00000071565": 1, "species_10050114": 5, "reaction_10044090": 2, "species_10042680": 2, "species_10044088": 3, "reaction_10071769": 3, "species_10071589": 2, "ENSBTAT00000082240": 2, "species_10071585": 2, "ENSBTAT00000022288": 2, "species_10071591": 4, "F1MPG0": 5, "A0A3Q1M1S8": 5, "reaction_10071640": 4, "species_10071626": 5, "Q3MHE4": 9, "ENSBTAT00000003556": 2, "E1B9Q4": 7, "ENSBTAT00000001867": 2, "species_10071603": 5, "reaction_10071628": 3, "species_5358514": 1, "species_10071624": 5, "reaction_10071630": 6, "species_5358610": 1, "species_109966": 1, "species_164121": 2, "species_10033501": 3, "ENSBTAT00000031920": 1, "reaction_10071767": 4, "species_10071599": 2, "species_10071595": 3, "reaction_10071607": 4, "species_10071605": 8, "reaction_10071622": 2, "species_10071619": 8, "reaction_10071638": 3, "species_10071634": 2, "ENSBTAT00000012365": 2, "species_10071636": 8, "E1BF15": 2, "reaction_10071617": 3, "species_5358527": 1, "species_10071613": 5, "A0A3Q1LUI6": 3, "ENSBTAT00000076740": 2, "species_10071615": 4, "reaction_10071765": 4, "species_10071611": 2, "reaction_10047196": 3, "species_10047192": 20, "A0A3Q1M4Y0": 5, "ENSBTAT00000082241": 1, "A0A3Q1LQC6": 5, "ENSBTAT00000076718": 1, "A6QP89": 5, "ENSBTAT00000043649": 1, "A6QPA6": 6, "ENSBTAT00000001120": 1, "F1N2G0": 6, "ENSBTAT00000007359": 1, "A0A3Q1LVZ9": 6, "ENSBTAT00000085880": 1, "A0JNJ5": 6, "ENSBTAT00000054271": 1, "A0A3Q1M165": 6, "ENSBTAT00000075504": 1, "Q1RMM7": 6, "ENSBTAT00000057007": 1, "O62654": 5, "ENSBTAT00000007041": 1, "Q6T8D8": 5, "ENSBTAT00000015579": 1, "P48616": 5, "ENSBTAT00000024572": 8, "A0A3Q1MC60": 5, "ENSBTAT00000086078": 1, "Q5KR48": 5, "ENSBTAT00000046179": 1, "P68138": 5, "ENSBTAT00000006534": 1, "A0A3Q1LWR2": 5, "ENSBTAT00000083316": 1, "F6QIC1": 5, "ENSBTAT00000014452": 1, "G3MYN5": 5, "ENSBTAT00000063025": 1, "G3N264": 5, "ENSBTAT00000065361": 1, "species_10047194": 23, "reaction_10047198": 3, "species_10047181": 23, "reaction_10047200": 3, "species_10047177": 23, "reaction_10047186": 4, "species_10047183": 7, "reaction_10071824": 3, "species_10071821": 4, "A0A3Q1LSF6": 3, "ENSBTAT00000067149": 1, "reaction_10077468": 3, "species_10071836": 3, "ENSBTAT00000008819": 6, "species_10077464": 2, "E1BN71": 3, "ENSBTAT00000008184": 1, "species_10077466": 3, "P07501": 2, "reaction_10071843": 6, "species_10071828": 2, "species_10071830": 2, "species_10071834": 2, "species_10071832": 2, "species_10071840": 2, "ENSBTAT00000085692": 1, "reaction_10071819": 3, "species_10071816": 6, "F1MY95": 3, "ENSBTAT00000044879": 1, "Q52PG9": 3, "ENSBTAT00000011882": 1, "F1MVI5": 3, "ENSBTAT00000045500": 1, "A0A3Q1LV43": 2, "ENSBTAT00000072593": 1, "A0A3Q1M5I5": 2, "ENSBTAT00000066696": 1, "reaction_10053180": 10, "species_10053175": 8, "Q3T0C6": 3, "ENSBTAT00000018795": 1, "A6QLL5": 3, "ENSBTAT00000018181": 1, "A2VDL6": 3, "ENSBTAT00000049161": 1, "E1B8N5": 3, "ENSBTAT00000013951": 1, "A0A3Q1MJB8": 3, "ENSBTAT00000077228": 1, "A0A3Q1LWV7": 3, "ENSBTAT00000073582": 1, "species_10053178": 8, "reaction_10091759": 3, "species_9684063": 1, "reaction_10048787": 6, "species_111875": 1, "species_10048770": 2, "ENSBTAT00000078158": 2, "species_10048785": 5, "reaction_10047893": 3, "species_10047890": 2, "ENSBTAT00000077323": 1, "reaction_10071876": 3, "species_10071873": 5, "E1BEH3": 2, "ENSBTAT00000004382": 1, "A0A3Q1MT89": 3, "ENSBTAT00000075452": 1, "Q0P5A0": 3, "ENSBTAT00000005929": 1, "F1MX91": 3, "ENSBTAT00000032182": 1, "reaction_10035579": 6, "species_10035564": 6, "P10123": 5, "ENSBTAT00000047900": 2, "species_2473611": 2, "species_10035566": 5, "species_10035576": 3, "reaction_10065597": 6, "species_10065594": 2, "reaction_10065644": 3, "species_10035562": 4, "reaction_10035406": 3, "species_10035401": 3, "species_10035404": 2, "reaction_10065646": 3, "species_2473615": 1, "species_2473604": 2, "species_10065601": 5, "ENSBTAT00000006585": 1, "reaction_10088914": 3, "species_8960974": 2, "reaction_10065604": 3, "reaction_10077751": 8, "species_6786220": 1, "species_6786225": 1, "species_10077748": 2, "ENSBTAT00000085962": 1, "reaction_10035558": 3, "species_10035556": 4, "reaction_10065606": 4, "species_2565923": 3, "reaction_10049433": 3, "species_10049430": 2, "ENSBTAT00000065246": 1, "reaction_10049464": 3, "species_10049461": 4, "Q3SYU3": 2, "ENSBTAT00000034015": 1, "E1BEU4": 2, "ENSBTAT00000001238": 1, "A0A3Q1LWM2": 2, "ENSBTAT00000075196": 1, "reaction_10049440": 3, "species_10049437": 2, "ENSBTAT00000007448": 1, "reaction_10049447": 3, "species_442320": 1, "species_10049444": 2, "ENSBTAT00000010771": 1, "reaction_10071469": 3, "species_10071466": 2, "ENSBTAT00000006554": 1, "reaction_10070735": 3, "species_113542": 1, "species_10070732": 2, "ENSBTAT00000017818": 1, "reaction_10071280": 3, "species_10071266": 2, "ENSBTAT00000037204": 2, "species_10071276": 3, "F1MCV8": 3, "ENSBTAT00000008743": 1, "A0A3Q1N598": 3, "ENSBTAT00000079328": 1, "species_10071278": 4, "A0A452DK44": 2, "reaction_10071490": 3, "species_114632": 3, "species_10071487": 2, "reaction_10087365": 3, "species_8941540": 3, "species_209785": 5, "species_8941541": 3, "species_10087362": 5, "A4IFE5": 2, "ENSBTAT00000027912": 1, "Q08E42": 2, "ENSBTAT00000084512": 1, "F6PRJ0": 2, "ENSBTAT00000005636": 1, "A5PK13": 2, "ENSBTAT00000085971": 1, "reaction_10071476": 3, "species_10071473": 2, "ENSBTAT00000012110": 1, "reaction_10086343": 3, "species_8932838": 4, "species_8932842": 4, "species_10086340": 2, "ENSBTAT00000018143": 1, "reaction_10071462": 3, "species_10071459": 2, "F1N136": 2, "ENSBTAT00000002985": 1, "reaction_10047930": 3, "species_30991": 2, "species_113578": 12, "species_10047927": 6, "A0A3Q1N569": 2, "ENSBTAT00000072103": 1, "reaction_10065369": 5, "species_2395852": 2, "species_2395817": 4, "species_10065366": 3, "ENSBTAT00000025978": 1, "reaction_10065371": 5, "species_2395868": 1, "species_2395878": 1, "species_10065356": 5, "F1MLL8": 2, "ENSBTAT00000003218": 1, "reaction_10065386": 5, "species_2395963": 1, "species_2395964": 1, "species_10065375": 4, "ENSBTAT00000004527": 1, "reaction_10065359": 5, "species_2395822": 1, "species_2395855": 1, "reaction_10065760": 6, "species_2509796": 1, "species_2509805": 4, "species_10065757": 3, "A1A4Q9": 2, "ENSBTAT00000053197": 1, "species_2509819": 2, "reaction_10065328": 5, "species_2393945": 1, "species_2393950": 1, "species_10065325": 3, "A7MBI8": 2, "ENSBTAT00000015090": 1, "reaction_10065763": 6, "species_2509811": 3, "species_2509792": 6, "reaction_10065362": 5, "reaction_10065378": 5, "species_2395880": 1, "species_2395877": 1, "reaction_10065381": 5, "species_2395883": 2, "reaction_10065383": 5, "reaction_10065319": 5, "species_1131972": 1, "species_10065316": 3, "F1MMR8": 2, "ENSBTAT00000068724": 1, "reaction_10072489": 3, "species_10072485": 2, "ENSBTAT00000007584": 2, "species_10072480": 2, "ENSBTAT00000009843": 2, "species_10072487": 4, "E1BIZ3": 3, "E1BP93": 3, "reaction_10072497": 2, "species_10072495": 3, "reaction_10033379": 2, "species_10033367": 2, "ENSBTAT00000083861": 3, "species_10033377": 3, "E1BG94": 2, "ENSBTAT00000005182": 1, "E1BD75": 2, "ENSBTAT00000023554": 1, "reaction_10033412": 4, "species_10033390": 3, "Q56JZ0": 4, "ENSBTAT00000023040": 2, "A0A3Q1LIW5": 3, "ENSBTAT00000067336": 3, "species_10033410": 5, "species_10033388": 2, "reaction_10085788": 3, "species_1524163": 1, "species_10085786": 3, "P02720": 2, "reaction_10086064": 3, "species_10086060": 2, "ENSBTAT00000071992": 2, "species_10086062": 3, "A0A3Q1LZP9": 2, "reaction_10085808": 4, "species_10035781": 5, "species_10085792": 2, "ENSBTAT00000071421": 2, "species_10085794": 5, "A0A3Q1MRL1": 3, "reaction_10085024": 5, "species_8865642": 1, "species_8865629": 1, "species_10085021": 2, "ENSBTAT00000017353": 1, "reaction_10059141": 5, "species_1500596": 10, "species_10059138": 5, "E1BLQ9": 2, "ENSBTAT00000012081": 1, "reaction_10059063": 5, "species_10059060": 3, "A0A3Q1LRY5": 3, "ENSBTAT00000082323": 1, "A0A3Q1MPV1": 3, "ENSBTAT00000074052": 1, "reaction_10085798": 3, "species_10085796": 3, "reaction_10059094": 5, "species_10059079": 4, "E1BCN8": 2, "ENSBTAT00000000037": 1, "reaction_10090489": 4, "species_9025001": 3, "species_9026761": 2, "species_10090486": 3, "Q2NKS0": 2, "ENSBTAT00000012836": 1, "reaction_10090480": 4, "species_10039964": 3, "F1MUX5": 3, "ENSBTAT00000016866": 1, "A0A3Q1LY34": 3, "ENSBTAT00000075425": 1, "reaction_10090491": 4, "species_9024768": 1, "species_9026915": 1, "reaction_10044835": 5, "species_353560": 3, "species_353575": 1, "species_10044832": 3, "ENSBTAT00000023087": 1, "reaction_10044837": 5, "species_353555": 1, "reaction_10076360": 6, "species_351627": 3, "species_351628": 3, "species_10076357": 3, "E1BMK1": 2, "ENSBTAT00000021618": 1, "E1BMS3": 2, "ENSBTAT00000021603": 1, "reaction_10043978": 5, "species_209818": 5, "species_10043975": 3, "ENSBTAT00000021031": 1, "reaction_10044828": 8, "species_351630": 2, "species_10043921": 6, "ENSBTAT00000071301": 1, "reaction_10043980": 6, "species_352329": 3, "species_351639": 2, "species_352331": 3, "reaction_10043986": 9, "reaction_10043924": 5, "species_622410": 1, "reaction_10043956": 5, "species_352326": 5, "reaction_10066745": 3, "species_10066741": 2, "ENSBTAT00000021980": 2, "species_10066743": 3, "Q3SYU1": 2, "reaction_10066712": 6, "species_10066701": 5, "E1B9B6": 3, "ENSBTAT00000013805": 3, "E1BCU9": 3, "ENSBTAT00000015459": 2, "species_10066709": 2, "species_10066690": 3, "species_10066699": 2, "reaction_10081563": 4, "species_10066694": 2, "species_10066696": 5, "reaction_10081595": 5, "species_10081585": 2, "species_10081592": 3, "reaction_10080730": 3, "species_10080726": 2, "ENSBTAT00000015051": 2, "species_10080728": 3, "E1BQ34": 2, "reaction_10081629": 5, "species_10081626": 2, "ENSBTAT00000039179": 1, "reaction_10066704": 4, "reaction_10080722": 6, "species_10066668": 6, "A0A3Q1MHM3": 3, "ENSBTAT00000072457": 1, "A0A3Q1MBC1": 2, "ENSBTAT00000084811": 2, "species_10066659": 3, "species_10066666": 4, "species_10078728": 3, "reaction_10066870": 5, "species_10066862": 2, "species_10066867": 5, "reaction_10081622": 5, "species_10081619": 7, "reaction_10078731": 5, "species_10078718": 3, "ENSBTAT00000009545": 2, "reaction_10066670": 4, "reaction_10078720": 5, "species_10078714": 2, "reaction_10081602": 5, "species_10081599": 2, "ENSBTAT00000008055": 1, "reaction_10039801": 3, "species_10038468": 3, "ENSBTAT00000083057": 2, "species_10039797": 2, "Q32L05": 3, "ENSBTAT00000074490": 1, "species_10039799": 3, "A0A3Q1M5V7": 3, "reaction_10039852": 3, "species_10039803": 2, "species_10039850": 3, "reaction_10038033": 3, "species_10038023": 3, "species_10038027": 3, "ENSBTAT00000065027": 2, "species_10038031": 3, "G3MX31": 3, "reaction_10038035": 5, "species_10038019": 2, "ENSBTAT00000057027": 2, "species_10038015": 2, "ENSBTAT00000009521": 2, "species_10038029": 5, "F1MWP1": 2, "Q1JQB2": 2, "reaction_10033833": 4, "species_30721": 1, "species_34979": 2, "species_10033830": 3, "A0A3Q1LXH7": 2, "ENSBTAT00000083727": 1, "reaction_10033849": 5, "species_30158": 2, "species_70919": 1, "species_10033846": 2, "A0A3Q1MBB6": 2, "ENSBTAT00000074746": 1, "reaction_10054585": 4, "species_175992": 1, "species_10054582": 2, "Q5EA83": 2, "ENSBTAT00000013083": 1, "reaction_10077758": 7, "species_6786250": 2, "species_10077755": 2, "ENSBTAT00000023529": 1, "reaction_10086033": 5, "species_8876775": 1, "species_10086030": 2, "ENSBTAT00000010790": 1, "reaction_10033840": 5, "species_10033837": 2, "ENSBTAT00000021647": 1, "reaction_10059066": 5, "species_1524042": 5, "species_1524064": 2, "species_1524072": 3, "species_1524067": 1, "species_10058823": 4, "ENSBTAT00000000072": 1, "reaction_10092237": 4, "species_9707575": 1, "species_10092233": 5, "E1BB01": 4, "ENSBTAT00000025702": 2, "E1BJL3": 7, "ENSBTAT00000005416": 4, "species_10055987": 4, "species_10092235": 3, "reaction_10092269": 2, "species_10092259": 4, "E1BE98": 4, "species_10092267": 3, "reaction_10092239": 3, "species_10092231": 3, "reaction_10092271": 3, "reaction_10092225": 3, "species_9707310": 4, "species_71185": 23, "species_10092221": 2, "E1BLL1": 3, "ENSBTAT00000053034": 1, "species_10092223": 3, "reaction_10092227": 3, "species_10064743": 7, "P01966": 11, "ENSBTAT00000037545": 1, "species_917955": 5, "species_10064749": 4, "reaction_10052914": 3, "species_9707308": 1, "reaction_10092214": 6, "species_10092210": 6, "species_9707624": 1, "species_9707647": 1, "species_10092212": 6, "reaction_10081561": 2, "species_10066422": 2, "reaction_10091685": 4, "species_10091677": 9, "F1MGU0": 3, "ENSBTAT00000036227": 1, "Q0VCT3": 10, "ENSBTAT00000020830": 1, "F1MMS4": 10, "ENSBTAT00000010016": 1, "A3KN17": 10, "ENSBTAT00000003522": 1, "E1BGK3": 10, "ENSBTAT00000017541": 1, "E1BGN3": 20, "ENSBTAT00000033058": 2, "species_10035227": 2, "species_10091683": 9, "species_10040161": 2, "reaction_10038540": 2, "species_10038538": 12, "CHEBI:15986": 4, "F1N079": 5, "ENSBTAT00000028108": 1, "Q3ZBF2": 5, "ENSBTAT00000036177": 1, "A7YWH5": 5, "ENSBTAT00000017339": 1, "A0A3Q1M1J8": 5, "ENSBTAT00000066873": 1, "A0A3Q1LGY5": 5, "ENSBTAT00000071579": 1, "Q5E950": 5, "ENSBTAT00000008363": 1, "species_10038529": 13, "reaction_10038947": 6, "species_30187": 4, "species_10038531": 15, "species_30185": 4, "species_29892": 3, "species_29604": 4, "species_10038542": 12, "reaction_10038949": 2, "reaction_10038534": 6, "reaction_10087577": 2, "species_10062035": 2, "ENSBTAT00000081723": 2, "species_10062840": 2, "A0A3Q1M646": 9, "reaction_10087579": 2, "species_10062810": 2, "A0A3Q1MQC5": 5, "ENSBTAT00000074238": 1, "species_10062812": 2, "reaction_10087581": 4, "species_10060135": 2, "species_10060159": 2, "species_10060111": 2, "species_10060183": 5, "reaction_10087583": 2, "species_10062400": 2, "ENSBTAT00000044319": 3, "species_10062823": 2, "E1BKJ9": 7, "reaction_10087569": 2, "species_10062025": 2, "ENSBTAT00000065364": 2, "species_10062790": 2, "G3MXK9": 4, "reaction_10087571": 2, "species_10062031": 2, "ENSBTAT00000017548": 2, "species_10062821": 2, "F1MSJ7": 5, "reaction_10087573": 4, "species_10062017": 2, "species_10062045": 2, "species_10062041": 2, "species_10062749": 4, "reaction_10062071": 2, "species_10062037": 2, "ENSBTAT00000067622": 2, "species_10062069": 2, "A0A3Q1LYA4": 4, "reaction_10087563": 2, "species_10062027": 2, "ENSBTAT00000063888": 2, "species_10062801": 2, "G3N021": 4, "reaction_10087565": 2, "species_10062023": 2, "species_10062781": 2, "reaction_10087567": 3, "species_10062019": 2, "species_10062043": 2, "species_10062763": 3, "reaction_10087585": 2, "species_10062033": 2, "species_10062832": 2, "reaction_10087587": 2, "species_10062021": 2, "species_10062772": 2, "reaction_10087589": 2, "species_10062015": 2, "species_10062709": 2, "reaction_10044446": 7, "species_10044438": 4, "species_10044434": 2, "species_10044410": 3, "species_10044424": 2, "species_10044444": 7, "reaction_10044726": 6, "species_10044722": 3, "A0A3Q1MXW3": 3, "ENSBTAT00000084577": 1, "species_10044704": 3, "species_10044724": 9, "reaction_10092287": 5, "species_10092281": 8, "A0A3Q1LUD8": 3, "ENSBTAT00000069043": 2, "species_10092277": 3, "species_10092284": 2, "reaction_10092273": 3, "species_10092261": 2, "species_3785707": 2, "reaction_10092289": 3, "species_10092279": 4, "reaction_10092293": 4, "reaction_10057639": 3, "species_10057636": 4, "E1B9M4": 2, "ENSBTAT00000014309": 1, "reaction_10065673": 5, "species_10065666": 3, "CHEBI:16254": 1, "species_10065670": 5, "ENSBTAT00000074877": 1, "reaction_10091560": 4, "species_10048186": 3, "species_10065649": 3, "reaction_10065675": 4, "reaction_10065677": 3, "species_2473606": 1, "reaction_10065679": 3, "species_2473607": 1, "species_2473617": 2, "reaction_10065664": 3, "species_10065654": 3, "species_10065662": 4, "reaction_10065683": 3, "species_10065681": 3, "reaction_10065687": 4, "species_10065685": 3, "reaction_10091558": 4, "species_10048190": 2, "species_10065652": 2, "reaction_10068899": 2, "species_10068891": 2, "ENSBTAT00000086463": 2, "species_10068893": 2, "A0A3Q1NLC4": 2, "reaction_10040355": 3, "species_10040351": 4, "E1BC36": 7, "ENSBTAT00000068675": 1, "species_10040345": 3, "A0A3Q1LYR9": 3, "ENSBTAT00000083400": 1, "A7MBB9": 3, "ENSBTAT00000014685": 1, "species_10040353": 6, "reaction_10088026": 5, "species_2173763": 1, "species_8954142": 1, "species_8952253": 1, "species_10088023": 2, "ENSBTAT00000009888": 1, "reaction_10058910": 5, "species_1524028": 4, "species_1498750": 3, "species_10058868": 7, "reaction_10058871": 5, "species_975614": 3, "reaction_10057007": 3, "species_1237009": 3, "species_10049238": 4, "P47865": 3, "ENSBTAT00000000993": 1, "reaction_10081968": 6, "species_10081949": 4, "species_10081955": 4, "species_10081965": 3, "A0A3Q1LIS5": 2, "ENSBTAT00000068812": 1, "A0A3Q1MXD6": 2, "ENSBTAT00000072609": 1, "reaction_10058790": 5, "species_10058787": 5, "Q1LZA1": 3, "ENSBTAT00000045723": 1, "F1N0H3": 3, "ENSBTAT00000023581": 1, "reaction_10057062": 5, "species_10057046": 6, "species_10057060": 5, "reaction_10037739": 2, "species_10037735": 2, "ENSBTAT00000071269": 3, "species_10037737": 2, "reaction_10058985": 5, "species_1524083": 1, "species_1498773": 2, "species_1524089": 1, "species_10058952": 3, "ENSBTAT00000079163": 1, "reaction_10058955": 5, "species_1524075": 1, "species_1524079": 1, "reaction_10058993": 5, "species_1524069": 2, "species_1524081": 1, "species_10035773": 3, "reaction_10058998": 5, "species_1524080": 1, "reaction_10045466": 3, "species_10045463": 2, "Q866T7": 2, "ENSBTAT00000028966": 1, "reaction_10045455": 3, "species_10045452": 2, "E1BLU3": 2, "ENSBTAT00000015039": 1, "reaction_10045444": 3, "species_10045441": 3, "D7R519": 2, "ENSBTAT00000015932": 1, "G5E5X7": 2, "ENSBTAT00000037612": 1, "reaction_10084238": 3, "species_10084224": 3, "ENSBTAT00000055485": 2, "species_10084234": 3, "G3N3N1": 3, "ENSBTAT00000063023": 1, "species_10084236": 4, "F1MB46": 3, "reaction_10084291": 5, "species_10084286": 3, "E1BJA0": 3, "ENSBTAT00000083670": 1, "species_10084288": 3, "species_10084272": 3, "ENSBTAT00000012236": 2, "reaction_10084261": 5, "species_10084252": 3, "Q08DE8": 3, "ENSBTAT00000016976": 1, "species_10084254": 3, "species_10084259": 2, "ENSBTAT00000082752": 1, "reaction_10084228": 3, "species_10084220": 2, "ENSBTAT00000077895": 2, "species_10084226": 3, "A0A3Q1M443": 2, "reaction_10084276": 3, "species_10084268": 3, "species_10084274": 4, "E1BHZ5": 2, "reaction_10084246": 3, "species_10084242": 2, "ENSBTAT00000061025": 2, "species_10083720": 3, "species_10084244": 4, "F1N746": 2, "reaction_10044801": 9, "species_351164": 4, "species_29610": 4, "species_10044798": 2, "ENSBTAT00000085149": 1, "reaction_10041177": 8, "species_192114": 2, "species_10041174": 2, "E1BM29": 2, "ENSBTAT00000006957": 1, "reaction_10041500": 9, "species_194634": 1, "species_194644": 2, "species_10041497": 2, "ENSBTAT00000002582": 1, "reaction_10041206": 8, "species_193846": 1, "reaction_10044232": 9, "species_211973": 1, "species_10044229": 2, "species_10035975": 6, "F1ML85": 3, "ENSBTAT00000010187": 1, "CHEBI:28119": 2, "F1MYL2": 2, "ENSBTAT00000016391": 2, "reaction_10041195": 8, "species_192148": 1, "species_10041094": 3, "A0A3Q1NAD5": 2, "ENSBTAT00000070426": 1, "reaction_10043964": 8, "species_8963870": 2, "species_8963879": 1, "species_10043961": 2, "ENSBTAT00000084891": 1, "reaction_10044225": 8, "species_215607": 1, "species_215622": 1, "species_10043907": 3, "ENSBTAT00000003588": 1, "reaction_10043971": 9, "species_209804": 6, "species_209800": 2, "species_10043968": 2, "ENSBTAT00000022485": 1, "reaction_10044293": 8, "reaction_10044280": 8, "species_213162": 1, "species_213163": 1, "species_10044277": 2, "G3MYW0": 2, "ENSBTAT00000063781": 1, "reaction_10044218": 8, "species_211892": 1, "species_211944": 1, "species_10044201": 4, "reaction_10044250": 8, "species_211993": 1, "species_211952": 1, "species_10035908": 3, "Q2KJJ2": 3, "ENSBTAT00000000869": 1, "reaction_10044477": 8, "species_156522": 1, "species_156523": 1, "species_10044474": 5, "reaction_10044223": 8, "species_213155": 1, "species_213151": 1, "species_10044220": 2, "reaction_10035865": 9, "species_143501": 3, "species_76424": 2, "species_10035858": 5, "reaction_10035861": 8, "species_47687": 1, "species_34889": 3, "reaction_10044275": 8, "species_211939": 1, "species_211927": 1, "species_10044272": 2, "F1MRH2": 2, "ENSBTAT00000040300": 1, "reaction_10044182": 8, "species_10044179": 5, "reaction_10035977": 9, "species_38985": 1, "species_38987": 2, "species_10035962": 2, "reaction_10044265": 8, "species_211855": 1, "species_211937": 1, "species_10044262": 2, "reaction_10044204": 8, "species_211906": 1, "species_211894": 1, "reaction_10044270": 8, "species_211977": 1, "species_211967": 1, "species_10044267": 2, "A0A3Q1MU42": 2, "ENSBTAT00000079854": 1, "reaction_10044167": 8, "species_76452": 2, "species_10044164": 2, "G3MYH2": 4, "ENSBTAT00000065779": 2, "reaction_10035911": 9, "species_39703": 1, "species_76455": 1, "reaction_10035878": 8, "species_10035875": 2, "reaction_10059035": 5, "species_1500603": 2, "species_10059032": 4, "Q17QM4": 2, "ENSBTAT00000010310": 1, "reaction_10059082": 5, "reaction_10059130": 5, "species_10059127": 2, "A0A3Q1MLB5": 2, "ENSBTAT00000070509": 1, "reaction_10059150": 5, "species_10059147": 4, "F1MRD9": 2, "ENSBTAT00000024637": 1, "reaction_10076994": 6, "species_5696414": 1, "species_113532": 2, "species_10076991": 2, "Q5E9S4": 2, "ENSBTAT00000013587": 1, "reaction_10077004": 5, "species_5696449": 1, "species_6782195": 1, "reaction_10058892": 5, "species_1498728": 4, "species_1500594": 4, "species_10058889": 5, "ENSBTAT00000004368": 1, "reaction_10059006": 5, "reaction_10058894": 4, "reaction_10058961": 5, "reaction_10058819": 5, "species_1500593": 1, "species_10058816": 2, "A0A3Q1LUK0": 2, "reaction_10058948": 5, "reaction_10083572": 5, "species_10083569": 2, "ENSBTAT00000010259": 1, "reaction_10038938": 3, "species_10038932": 4, "species_10038936": 5, "reaction_10083614": 3, "species_10083610": 3, "Q3T0U4": 3, "ENSBTAT00000040283": 1, "Q32KM7": 3, "ENSBTAT00000011923": 1, "species_10083594": 2, "A0A3Q1M564": 3, "ENSBTAT00000077795": 1, "species_10083612": 4, "reaction_10060553": 5, "species_1806289": 1, "species_1806212": 1, "species_10060465": 5, "ENSBTAT00000078957": 1, "reaction_10060537": 5, "species_1806195": 2, "species_1806198": 2, "species_10060489": 7, "E1BE68": 4, "ENSBTAT00000046627": 1, "reaction_10060468": 5, "reaction_10088526": 5, "species_8952909": 3, "species_8952905": 1, "species_10088523": 2, "ENSBTAT00000028950": 1, "reaction_10037674": 3, "species_10037670": 6, "A0A3Q1M2Q2": 8, "ENSBTAP00000064310": 1, "species_10037644": 2, "species_10037672": 6, "F1MUT9": 5, "reaction_10037678": 2, "species_10037626": 3, "reaction_10037630": 4, "species_10037275": 4, "F6R2C4": 4, "ENSBTAT00000025701": 2, "species_10037628": 3, "reaction_10047900": 5, "species_427899": 1, "species_139827": 1, "species_10047897": 2, "reaction_10076824": 5, "species_5696066": 3, "species_6814795": 3, "species_5696069": 1, "species_5696026": 1, "species_5696037": 3, "species_10076821": 3, "A0A3Q1MFM9": 2, "ENSBTAT00000074114": 1, "reaction_10085340": 5, "species_10085337": 4, "E1B9I9": 2, "ENSBTAT00000013851": 1, "A0A3Q1MUM3": 2, "ENSBTAT00000079883": 1, "A0A3Q1N293": 2, "ENSBTAT00000069345": 1, "reaction_10059091": 5, "species_426955": 2, "species_10059088": 3, "G3MZU2": 2, "ENSBTAT00000065725": 1, "reaction_10059044": 5, "species_426910": 7, "species_10059041": 4, "Q3T103": 2, "ENSBTAT00000010454": 1, "reaction_10071344": 4, "species_10071340": 3, "Q2KHY1": 3, "ENSBTAT00000002436": 1, "species_171142": 5, "species_10071342": 4, "reaction_10059849": 5, "species_33625": 2, "species_1602419": 1, "reaction_10058943": 5, "species_1498724": 3, "reaction_10085310": 5, "species_1806234": 3, "species_10085307": 4, "A0A3Q1MI45": 2, "ENSBTAT00000070851": 1, "F1MFD9": 2, "ENSBTAT00000012114": 1, "A0A3Q1LWY5": 2, "ENSBTAT00000073265": 1, "reaction_10058945": 5, "reaction_10058880": 5, "species_10058800": 3, "reaction_10058916": 5, "species_1498722": 2, "reaction_10059014": 5, "species_10059011": 4, "reaction_10059016": 5, "species_1483256": 5, "species_1498740": 3, "reaction_10059018": 5, "reaction_10058826": 5, "species_1524047": 2, "species_1524038": 2, "reaction_10059021": 5, "species_1498730": 2, "reaction_10058877": 5, "reaction_10058812": 5, "reaction_10058913": 5, "species_1524027": 2, "reaction_10058983": 5, "species_1524085": 2, "species_10058931": 3, "reaction_10059847": 5, "species_1602415": 1, "reaction_10058934": 5, "reaction_10058809": 5, "species_10058806": 6, "A0A3Q1MPE0": 2, "ENSBTAT00000079571": 1, "reaction_10058970": 5, "reaction_10058829": 5, "reaction_10058990": 5, "species_10058987": 5, "reaction_10059856": 5, "species_1602390": 2, "reaction_10059858": 5, "reaction_10085826": 5, "species_8874447": 3, "CHEBI:17810": 1, "CHEBI:17476": 1, "species_8874450": 3, "CHEBI:36313": 1, "CHEBI:36314": 1, "species_10085823": 2, "ENSBTAT00000076823": 1, "reaction_10058996": 5, "reaction_10059121": 5, "species_10059118": 2, "ENSBTAT00000018461": 1, "reaction_10059073": 5, "species_10059070": 2, "ENSBTAT00000077015": 1, "reaction_10059101": 5, "species_110577": 1, "species_10059098": 2, "ENSBTAT00000007970": 1, "reaction_10057390": 3, "species_10057387": 6, "E1BM97": 3, "ENSBTAT00000061021": 1, "E1BL87": 3, "ENSBTAT00000022679": 1, "E1BIS4": 3, "ENSBTAT00000023219": 1, "reaction_10057607": 3, "species_10057385": 4, "reaction_10049326": 5, "species_433138": 1, "species_10049323": 2, "ENSBTAT00000006144": 1, "reaction_10049333": 5, "species_10049330": 2, "ENSBTAT00000078998": 1, "reaction_10051305": 5, "species_561049": 3, "CHEBI:104011": 2, "species_561052": 3, "species_561078": 3, "species_10051302": 4, "F1MIJ1": 2, "ENSBTAT00000018132": 1, "G3N1R8": 2, "ENSBTAT00000064695": 1, "F1MII8": 2, "ENSBTAT00000018139": 1, "reaction_10051314": 5, "species_429056": 2, "species_30034": 4, "species_10051311": 2, "ENSBTAT00000068956": 1, "reaction_10051307": 4, "species_549266": 16, "CHEBI:46020": 6, "CHEBI:6801": 6, "CHEBI:16737": 4, "CHEBI:65133": 4, "CHEBI:641": 6, "CHEBI:31941": 2, "species_549237": 16, "species_10051281": 4, "ENSBTAT00000055483": 1, "reaction_10051325": 5, "species_597604": 1, "species_597623": 1, "species_10051322": 2, "ENSBTAT00000016935": 1, "reaction_10051276": 5, "species_549261": 1, "species_549260": 1, "species_10051273": 2, "ENSBTAT00000013203": 1, "reaction_10051283": 4, "reaction_10051269": 3, "species_549264": 16, "CHEBI:42820": 4, "species_549250": 16, "reaction_10051286": 3, "reaction_10067993": 3, "species_10048710": 2, "species_10067989": 3, "ENSBTAT00000007194": 3, "species_10067991": 3, "E1B9H3": 2, "reaction_10071241": 5, "species_10071123": 5, "species_10071232": 4, "species_10071238": 4, "Q1RMH9": 3, "ENSBTAT00000004925": 1, "F1N7H0": 3, "ENSBTAT00000003437": 1, "reaction_10068008": 5, "species_10067995": 2, "species_10068005": 3, "E1BEI6": 27, "A0A3Q1M8V1": 2, "ENSBTAT00000066572": 1, "reaction_10071208": 6, "species_10071171": 4, "Q56JY0": 3, "ENSBTAT00000026632": 3, "species_10071169": 2, "species_10071195": 3, "species_10071205": 4, "reaction_10071313": 6, "species_10071304": 6, "Q0IIM3": 2, "ENSBTAT00000006600": 1, "Q148J7": 2, "ENSBTAT00000023720": 1, "Q3ZBG5": 2, "ENSBTAT00000007039": 1, "F1MIU2": 2, "ENSBTAT00000018131": 1, "F1MSS9": 2, "ENSBTAT00000017468": 1, "species_10071311": 2, "A0A3Q1MQM3": 2, "ENSBTAT00000074682": 1, "reaction_10071127": 3, "species_10071069": 2, "species_10071125": 4, "reaction_10092312": 3, "species_9709326": 1, "reaction_10040636": 9, "species_189385": 1, "species_189396": 1, "species_10040633": 2, "reaction_10047807": 6, "species_10047799": 7, "P80425": 6, "ENSBTAT00000024032": 2, "species_10047793": 7, "Q0II51": 3, "ENSBTAT00000078286": 1, "F1N1K9": 3, "ENSBTAT00000007749": 2, "species_159151": 4, "species_10047777": 8, "F1MTR3": 11, "ENSBTAT00000013167": 1, "Q5EA13": 5, "ENSBTAT00000068423": 1, "species_10047797": 2, "species_10047805": 15, "species_10047771": 5, "reaction_10092308": 3, "reaction_10092310": 5, "reaction_10067416": 3, "species_10067409": 6, "E1BE86": 5, "ENSBTAT00000005683": 1, "species_3299744": 7, "species_10067413": 4, "species_10067395": 5, "species_209799": 6, "reaction_10056408": 6, "species_1222424": 2, "species_10056405": 7, "reaction_10076891": 5, "species_5696199": 1, "species_5696194": 1, "species_10076888": 2, "ENSBTAT00000045076": 1, "reaction_10087866": 2, "species_10068573": 6, "reaction_10067388": 5, "species_10067385": 5, "F6R4N7": 3, "ENSBTAT00000018580": 1, "reaction_10068575": 3, "species_10067407": 3, "species_10068571": 4, "reaction_10069854": 2, "species_10069852": 4, "reaction_10067731": 6, "species_1655882": 2, "species_10067728": 3, "E1BKZ1": 3, "ENSBTAT00000009363": 1, "reaction_10080786": 5, "species_1247892": 2, "species_3341331": 1, "species_10080783": 3, "A0A3Q1M7E3": 2, "ENSBTAT00000068263": 1, "F1MCF5": 2, "ENSBTAT00000015939": 1, "reaction_10067735": 4, "species_3341308": 2, "species_189461": 4, "reaction_10034166": 6, "species_10034163": 3, "reaction_10067722": 5, "species_10067702": 4, "ENSBTAT00000000014": 3, "species_1614617": 3, "species_10067705": 4, "species_10067719": 3, "P35705": 2, "ENSBTAT00000011505": 1, "Q9BGI1": 2, "ENSBTAT00000011403": 2, "reaction_10068716": 5, "species_189481": 3, "species_10068713": 4, "reaction_10067375": 5, "species_3299683": 1, "species_10067372": 3, "E1BHL1": 4, "ENSBTAT00000008569": 1, "reaction_10067744": 5, "species_10067741": 3, "reaction_10068578": 6, "species_3697881": 1, "species_3697842": 1, "species_10067717": 2, "reaction_10067398": 5, "reaction_10066873": 4, "species_10066855": 5, "reaction_10066779": 5, "species_10066768": 8, "species_10066770": 7, "species_10066776": 4, "reaction_10066876": 5, "species_10044327": 5, "reaction_10066832": 3, "species_10066828": 9, "A6QLQ0": 7, "ENSBTAT00000000025": 1, "A0A3Q1LR89": 9, "ENSBTAT00000086711": 1, "E1BFG7": 3, "ENSBTAT00000006041": 1, "A0A3Q1MBA7": 5, "ENSBTAT00000073548": 1, "Q32KX7": 5, "ENSBTAT00000073960": 1, "F1MKU2": 3, "ENSBTAT00000061326": 1, "A0A3Q1MDR6": 3, "ENSBTAT00000076497": 1, "A0A3Q1MCA3": 3, "ENSBTAT00000074913": 1, "species_10066830": 14, "reaction_10066857": 5, "species_10066853": 4, "reaction_10066786": 5, "species_10066783": 2, "ENSBTAT00000011949": 1, "reaction_10088964": 3, "species_10066774": 2, "species_111793": 2, "reaction_10076298": 5, "species_10074450": 7, "A0A3Q1MIR9": 26, "ENSBTAT00000083355": 1, "G3X6W2": 34, "ENSBTAT00000014945": 2, "F6PSE2": 34, "ENSBTAT00000017598": 3, "species_10076295": 7, "reaction_10074429": 3, "species_10074417": 5, "species_10074425": 4, "species_10074427": 7, "reaction_10074431": 3, "species_10035718": 7, "species_3785706": 1, "reaction_10074446": 5, "species_10074438": 7, "species_10074443": 6, "reaction_10078369": 4, "reaction_10074453": 4, "species_10074448": 7, "reaction_10069684": 3, "species_10069680": 2, "species_10069676": 2, "ENSBTAT00000027216": 2, "species_10069682": 3, "F1MLB1": 2, "reaction_10076343": 3, "species_10068852": 6, "reaction_10068854": 3, "species_75165": 1, "reaction_10066630": 2, "species_10066626": 2, "ENSBTAT00000000437": 2, "species_10066628": 2, "reaction_10091401": 4, "species_10091329": 27, "species_10091333": 27, "species_10091399": 4, "Q3B7L5": 2, "ENSBTAT00000010532": 1, "A0A3Q1MS15": 2, "ENSBTAT00000083520": 1, "A0A3Q1NF19": 2, "ENSBTAT00000067422": 1, "reaction_10091336": 4, "reaction_10091354": 3, "species_10091344": 29, "species_10091342": 26, "species_10091338": 4, "reaction_10091356": 3, "species_10091340": 28, "reaction_10091404": 3, "species_10091358": 28, "species_10091360": 30, "reaction_10091365": 3, "species_10091362": 29, "reaction_10091351": 5, "species_10091349": 2, "ENSBTAT00000087052": 1, "reaction_10073481": 3, "species_10073456": 4, "A0A3Q1M6Y6": 4, "ENSBTAT00000069619": 1, "P68301": 4, "ENSBTAT00000034373": 1, "species_10073479": 4, "reaction_10073464": 4, "species_10073444": 4, "P37359": 4, "ENSBTAT00000022460": 2, "species_10073462": 4, "reaction_10073468": 3, "species_10073442": 3, "species_1132098": 4, "species_10073466": 3, "reaction_10073460": 3, "species_10073458": 4, "reaction_10073446": 3, "reaction_10075304": 4, "species_10075297": 6, "A0A3Q1NLY2": 12, "ENSBTAT00000085498": 1, "species_10075301": 5, "species_30555": 3, "reaction_10075323": 3, "species_10036900": 4, "F1N2F9": 3, "ENSBTAT00000081405": 1, "A0A3Q1LF81": 3, "ENSBTAT00000075817": 1, "species_10075316": 6, "species_10075321": 8, "reaction_10075306": 3, "species_10074778": 4, "reaction_10075326": 5, "species_5687670": 1, "reaction_10075319": 5, "species_10075312": 6, "Q58DH8": 2, "ENSBTAT00000000071": 2, "species_68454": 1, "species_10036890": 2, "reaction_10086350": 6, "species_189227": 3, "species_188995": 3, "species_189254": 3, "species_10086347": 2, "ENSBTAT00000084455": 1, "reaction_10057350": 4, "species_10057347": 4, "Q2KHY6": 2, "ENSBTAT00000003307": 1, "A2VDS4": 4, "ENSBTAT00000021523": 1, "E1BKR6": 4, "ENSBTAT00000046676": 1, "reaction_10057399": 3, "species_10057396": 2, "A0A3Q1N684": 2, "ENSBTAT00000081253": 1, "reaction_10033473": 2, "species_10033469": 2, "species_10033471": 2, "reaction_10084497": 8, "species_8857725": 1, "species_8857850": 1, "species_10084494": 4, "A0A3Q1N5P9": 2, "ENSBTAT00000081168": 1, "A0A452DJ48": 2, "ENSBTAT00000034976": 1, "reaction_10090466": 4, "species_9025155": 2, "species_9025151": 3, "CHEBI:138674": 1, "CHEBI:138673": 1, "species_10064558": 9, "reaction_10090468": 4, "species_9025960": 1, "reaction_10090477": 4, "species_9026407": 1, "reaction_10090470": 4, "species_9026047": 1, "reaction_10090472": 4, "species_9026293": 1, "reaction_10090474": 5, "species_9025012": 3, "species_9026307": 1, "reaction_10052888": 2, "species_10052876": 5, "E1BIG6": 9, "ENSBTAT00000046421": 1, "species_10052886": 5, "reaction_10052923": 3, "species_917810": 2, "species_10052920": 2, "reaction_10052907": 2, "species_10052903": 4, "species_10052905": 4, "reaction_10052925": 3, "species_10052874": 4, "species_10052872": 4, "reaction_10052909": 3, "reaction_10052911": 3, "reaction_10076099": 3, "species_10076095": 2, "ENSBTAT00000017371": 2, "species_10076097": 3, "Q5EEZ1": 2, "reaction_10052901": 4, "species_917882": 1, "species_10052898": 2, "reaction_10036076": 3, "species_10036050": 5, "reaction_10036052": 3, "species_10036048": 2, "species_10036044": 4, "reaction_10085967": 5, "species_8876310": 4, "species_8876304": 4, "species_10085964": 2, "ENSBTAT00000029140": 1, "reaction_10048768": 5, "species_425425": 6, "species_10048765": 2, "ENSBTAT00000033777": 1, "reaction_10048740": 3, "species_10048737": 3, "E1BD54": 2, "ENSBTAT00000045797": 1, "E1B9J2": 2, "ENSBTAT00000001818": 1, "reaction_10052040": 5, "species_893599": 1, "species_10052037": 4, "F6Q816": 2, "ENSBTAT00000050582": 1, "reaction_10064346": 7, "species_2022135": 4, "species_2160466": 1, "species_10064343": 3, "F1N191": 2, "ENSBTAT00000007580": 1, "reaction_10033935": 4, "species_71129": 1, "species_10033932": 2, "Q3ZBD3": 2, "ENSBTAT00000015750": 1, "reaction_10076974": 6, "species_5359061": 1, "species_10076971": 2, "Q32LE5": 2, "ENSBTAT00000077904": 1, "reaction_10033944": 4, "species_30337": 1, "species_31135": 2, "species_10033941": 3, "A0A3Q1LS65": 2, "ENSBTAT00000087453": 1, "reaction_10033962": 5, "species_31175": 2, "species_29666": 1, "species_29586": 1, "species_10033959": 2, "A0A3Q1MPJ4": 2, "ENSBTAT00000072597": 1, "reaction_10033953": 3, "species_10033950": 3, "reaction_10075181": 5, "species_10035844": 3, "A2VE43": 3, "ENSBTAT00000055617": 2, "species_10075178": 2, "species_10075170": 4, "reaction_10035846": 2, "species_10035842": 2, "reaction_10040183": 5, "species_10040167": 2, "ENSBTAT00000026619": 2, "species_10040179": 2, "ENSBTAT00000022773": 2, "species_10040175": 2, "ENSBTAT00000012322": 2, "species_10040171": 2, "ENSBTAT00000061540": 2, "species_10040181": 5, "E1BC42": 2, "Q08E12": 2, "A2VE40": 2, "A4IFH4": 2, "reaction_10033504": 3, "species_68452": 1, "species_69172": 1, "reaction_10038904": 3, "species_10038900": 2, "ENSBTAT00000063305": 2, "species_164569": 1, "species_10038902": 2, "G3N2I6": 2, "reaction_10040864": 1, "species_10040862": 2, "reaction_10055833": 2, "species_10055577": 2, "ENSBTAT00000023059": 2, "species_10055579": 2, "F1N0Y3": 4, "reaction_10055515": 3, "species_10055511": 2, "species_10055501": 3, "reaction_10055645": 4, "species_10055643": 15, "E1BF29": 4, "ENSBTAT00000012347": 2, "E1BG49": 4, "ENSBTAT00000011898": 2, "F1MCP5": 5, "ENSBTAT00000076641": 1, "A0A3Q1MG61": 5, "ENSBTAT00000076936": 1, "E1BC41": 3, "ENSBTAT00000060943": 1, "reaction_10055823": 2, "species_10055559": 2, "species_10055561": 2, "reaction_10055647": 3, "species_10055641": 11, "reaction_10055827": 2, "species_10055825": 3, "species_10055555": 3, "reaction_10055829": 2, "species_10055565": 2, "species_10055567": 2, "reaction_10055831": 2, "species_10055533": 2, "species_10055535": 2, "reaction_10090460": 4, "species_9024012": 4, "species_9024883": 1, "reaction_10090386": 5, "species_9024522": 3, "species_9024893": 1, "reaction_10090708": 8, "species_9024886": 1, "species_9037755": 1, "species_10090705": 3, "reaction_10091753": 3, "species_9648300": 1, "species_10084440": 5, "A0A3Q1LVF9": 4, "ENSBTAT00000074327": 1, "Q08DS7": 4, "ENSBTAT00000076585": 1, "A0A3Q1MCG7": 4, "ENSBTAT00000050604": 1, "species_10085164": 5, "reaction_10084824": 3, "species_10084753": 4, "A0A3Q1MWJ5": 5, "ENSBTAT00000082605": 1, "species_10075931": 3, "species_10084779": 3, "reaction_10085116": 3, "species_10085112": 10, "species_10085114": 11, "reaction_10085166": 4, "species_10085160": 13, "P11456": 6, "ENSBTAT00000067687": 1, "E1BK36": 3, "ENSBTAT00000019955": 1, "F1MJK4": 3, "ENSBTAT00000037742": 1, "Q32L97": 3, "ENSBTAT00000071023": 1, "A0A3S5ZPN6": 3, "ENSBTAT00000014549": 1, "species_10085162": 16, "reaction_10085134": 3, "species_10085126": 2, "G5E628": 3, "ENSBTAT00000029117": 1, "species_10085130": 2, "ENSBTAT00000084618": 2, "species_10085132": 3, "A0A3Q1MSK9": 2, "reaction_10085264": 3, "species_10085260": 2, "A0A3Q1NKA6": 3, "ENSBTAT00000070874": 1, "species_10085262": 3, "reaction_10084819": 4, "species_10084793": 3, "A0A3Q1MQM0": 3, "ENSBTAT00000080374": 1, "species_10084817": 11, "reaction_10084757": 3, "species_10084743": 3, "A0A3Q1LZP6": 3, "ENSBTAT00000081053": 1, "A0A3Q1LXE7": 3, "ENSBTAT00000080553": 1, "species_10084755": 4, "reaction_10084822": 5, "reaction_10089048": 3, "species_10089044": 4, "P02192": 3, "ENSBTAT00000084629": 1, "species_10089046": 5, "reaction_10089058": 3, "species_10089054": 4, "Q6WZ19": 3, "ENSBTAT00000021661": 1, "species_10089056": 5, "reaction_10089060": 3, "reaction_10089062": 3, "reaction_10049869": 5, "species_140912": 4, "species_10049625": 3, "ENSBTAT00000080155": 1, "reaction_10049628": 5, "reaction_10049871": 5, "species_10049632": 3, "ENSBTAT00000050191": 1, "reaction_10049635": 5, "reaction_10049371": 5, "species_435347": 2, "species_10049368": 2, "ENSBTAT00000068742": 1, "reaction_10049402": 3, "species_437295": 1, "species_10049399": 2, "ENSBTAT00000072292": 1, "reaction_10049378": 3, "species_10049375": 2, "ENSBTAT00000014489": 1, "reaction_10088912": 3, "species_29418": 2, "species_266099": 1, "species_10088909": 2, "ENSBTAT00000005787": 1, "reaction_10049358": 5, "species_446589": 7, "CHEBI:8428": 2, "species_446597": 7, "species_10049355": 2, "ENSBTAT00000074816": 1, "reaction_10049060": 5, "species_429130": 1, "species_10049057": 2, "ENSBTAT00000061504": 1, "reaction_10049078": 5, "species_429652": 3, "CHEBI:27372": 2, "species_429648": 3, "species_10049075": 2, "ENSBTAT00000004510": 1, "reaction_10049592": 7, "species_10049589": 2, "ENSBTAT00000035184": 1, "reaction_10049613": 3, "species_444154": 6, "species_444152": 6, "species_10049610": 2, "ENSBTAT00000045811": 1, "reaction_10049599": 7, "species_10049596": 2, "ENSBTAT00000087022": 1, "reaction_10049319": 5, "species_433120": 1, "species_176483": 2, "species_10049316": 2, "ENSBTAT00000066284": 1, "reaction_10049606": 3, "species_432019": 3, "species_10049603": 2, "ENSBTAT00000002712": 1, "reaction_10049080": 5, "species_429605": 4, "CHEBI:16494": 2, "species_429627": 4, "reaction_10051577": 3, "species_10051574": 3, "ENSBTAT00000004376": 1, "reaction_10051580": 3, "species_742353": 1, "reaction_10051587": 5, "species_744239": 1, "species_744233": 1, "reaction_10039874": 5, "species_158601": 2, "species_3499326": 1, "species_174384": 4, "species_10039871": 2, "A2VE55": 2, "reaction_10051899": 3, "species_879521": 1, "species_879517": 1, "species_10051896": 2, "reaction_10051866": 3, "species_879603": 4, "species_879628": 4, "species_10051863": 5, "E1BC23": 2, "ENSBTAT00000026117": 1, "E1BPV8": 2, "ENSBTAT00000021795": 1, "F1MM56": 2, "ENSBTAT00000003345": 1, "F1MYV0": 2, "ENSBTAT00000030217": 3, "reaction_10051843": 3, "species_879566": 5, "CHEBI:15544": 4, "species_879614": 5, "species_10051840": 2, "ENSBTAT00000001747": 1, "reaction_10091250": 3, "species_10051847": 3, "reaction_10051879": 3, "species_10051868": 5, "species_10051872": 5, "species_10051876": 2, "ENSBTAT00000055950": 1, "reaction_10070928": 3, "species_10070924": 3, "A0A3Q1LZ62": 3, "ENSBTAT00000084009": 1, "E1B9Y3": 3, "ENSBTAT00000032576": 1, "species_5229279": 3, "species_10070926": 4, "reaction_10051892": 3, "species_879559": 2, "species_879544": 2, "species_10051889": 3, "Q0VCQ2": 2, "ENSBTAT00000020526": 1, "A6QQD5": 2, "ENSBTAT00000044112": 1, "reaction_10036297": 5, "species_179740": 5, "CHEBI:17596": 10, "CHEBI:16750": 10, "CHEBI:16704": 14, "species_179741": 5, "species_10036294": 2, "ENSBTAT00000021720": 1, "reaction_10051545": 3, "species_727774": 7, "species_727737": 7, "species_10051542": 3, "ENSBTAT00000010219": 1, "reaction_10071001": 2, "species_10070999": 5, "Q2TA37": 5, "ENSBTAT00000002890": 1, "Q32PC9": 4, "ENSBTAT00000006363": 2, "species_10070983": 5, "reaction_10036283": 5, "species_179738": 6, "species_83928": 12, "CHEBI:17562": 10, "CHEBI:17256": 7, "species_179739": 6, "species_10036280": 2, "ENSBTAT00000075356": 1, "reaction_10051547": 3, "reaction_10071003": 3, "species_10070997": 2, "species_10070995": 3, "reaction_10070991": 3, "species_10070987": 2, "ENSBTAT00000017580": 2, "species_10070989": 6, "P02722": 2, "reaction_10073838": 5, "reaction_10036290": 5, "species_179737": 7, "species_179743": 7, "species_10036287": 2, "ENSBTAT00000024328": 1, "reaction_10036274": 3, "species_179747": 14, "species_83956": 7, "species_29850": 4, "species_5635947": 3, "CHEBI:16040": 2, "species_179742": 14, "species_10036271": 3, "ENSBTAT00000015948": 1, "reaction_10036276": 3, "reaction_10038660": 5, "species_10038657": 2, "P32007": 2, "ENSBTAT00000063682": 1, "reaction_10048747": 5, "species_10048744": 2, "ENSBTAT00000010384": 1, "reaction_10085896": 5, "species_10085893": 2, "ENSBTAT00000001624": 1, "reaction_10049083": 5, "reaction_10060218": 5, "species_1614584": 2, "reaction_10048821": 5, "species_428548": 2, "species_428614": 1, "species_10048818": 4, "A4FV52": 2, "ENSBTAT00000009255": 1, "A6QLI1": 2, "ENSBTAT00000007935": 1, "E1BA07": 2, "ENSBTAT00000001445": 1, "reaction_10049173": 3, "reaction_10048601": 5, "species_10048598": 2, "ENSBTAT00000076302": 1, "reaction_10048618": 5, "species_10048615": 4, "E1BCI8": 2, "ENSBTAT00000024019": 1, "A0A3S5ZPL9": 2, "ENSBTAT00000018852": 1, "A0A3Q1NIV4": 2, "ENSBTAT00000082311": 1, "reaction_10048594": 7, "species_10048591": 2, "ENSBTAT00000046583": 1, "reaction_10048795": 5, "species_428037": 3, "CHEBI:90799": 3, "CHEBI:47923": 2, "species_428026": 3, "species_10048792": 2, "ENSBTAT00000001891": 1, "reaction_10048802": 5, "species_427984": 3, "species_428003": 3, "CHEBI:46761": 1, "species_10048799": 2, "ENSBTAT00000030236": 1, "reaction_10048965": 5, "species_428592": 3, "species_428632": 3, "species_10048962": 2, "reaction_10048804": 9, "species_428027": 4, "CHEBI:17364": 2, "species_427997": 4, "reaction_10048491": 5, "species_10048488": 3, "E1BBH7": 2, "ENSBTAT00000006425": 1, "E1BIN2": 2, "ENSBTAT00000029024": 1, "reaction_10048478": 5, "species_10048475": 3, "E1BKK3": 2, "ENSBTAT00000019936": 1, "A0A3Q1M051": 2, "ENSBTAT00000071207": 1, "reaction_10049053": 3, "species_10049050": 2, "ENSBTAT00000066412": 1, "reaction_10089038": 3, "species_10089035": 2, "Q27994": 2, "ENSBTAT00000012109": 1, "reaction_10089024": 3, "species_10089021": 3, "A0A3Q1MA30": 2, "ENSBTAT00000042945": 1, "reaction_10085907": 3, "species_10085904": 2, "ENSBTAT00000010116": 1, "reaction_10089029": 3, "species_10089026": 2, "reaction_10049046": 3, "species_429078": 4, "species_429148": 4, "species_10049043": 2, "ENSBTAT00000079223": 1, "reaction_10037913": 4, "species_10037857": 3, "species_10037859": 3, "species_10037807": 7, "species_10037910": 5, "P30931": 4, "ENSBTAT00000009341": 3, "P22457": 6, "reaction_10037899": 2, "species_10037897": 2, "species_10037864": 4, "reaction_10037915": 4, "species_10037903": 4, "reaction_10037887": 5, "species_10037884": 6, "reaction_10037937": 4, "species_10037931": 2, "ENSBTAT00000085417": 2, "species_10037935": 6, "A0A3Q1NLA0": 2, "reaction_10037906": 3, "species_10037893": 4, "reaction_10037895": 4, "reaction_10048635": 3, "species_426219": 4, "species_426221": 4, "reaction_10037607": 3, "species_10037604": 6, "Q5E9U1": 3, "ENSBTAT00000014321": 1, "F1MUF3": 3, "ENSBTAT00000020298": 1, "E1B742": 3, "ENSBTAT00000025626": 1, "reaction_10044680": 3, "species_10044676": 3, "P40673": 3, "ENSBTAT00000020096": 1, "species_29428": 1, "species_10044678": 3, "reaction_10044142": 2, "species_10044132": 4, "Q0VC37": 5, "ENSBTAT00000017999": 5, "F1N2E0": 6, "ENSBTAT00000026657": 3, "species_10044140": 4, "reaction_10044144": 5, "species_10044108": 3, "species_10044098": 2, "species_10044094": 3, "species_10044106": 2, "species_10044104": 2, "reaction_10044146": 3, "species_10044118": 2, "species_10044120": 2, "species_10044122": 3, "reaction_10044116": 2, "species_10044114": 2, "reaction_10066489": 3, "species_10066480": 2, "ENSBTAT00000026496": 2, "species_10066482": 6, "F1N3C9": 3, "reaction_10065938": 2, "species_10065934": 2, "ENSBTAT00000021808": 2, "species_10065936": 2, "reaction_10066487": 4, "species_10066484": 5, "reaction_10084216": 5, "species_10054914": 3, "species_10039822": 3, "species_10043871": 2, "species_10039818": 2, "species_10084098": 6, "reaction_10084206": 3, "species_10084100": 7, "species_10084203": 6, "reaction_10084102": 3, "reaction_10084214": 4, "species_10084209": 2, "species_10084211": 5, "reaction_10039612": 2, "species_10039608": 3, "ENSBTAT00000075264": 2, "species_10039610": 3, "reaction_10039614": 2, "reaction_10084043": 2, "species_10084039": 2, "ENSBTAT00000009339": 4, "species_10084041": 3, "reaction_10084028": 3, "species_10084024": 2, "species_10084026": 4, "F6Q0H8": 4, "reaction_10084047": 3, "species_10084045": 4, "reaction_10084051": 2, "species_10084049": 3, "reaction_10087635": 2, "species_10039037": 20, "A0A452DII8": 5, "ENSBTAT00000017710": 1, "P05631": 5, "ENSBTAT00000081996": 1, "P05630": 5, "ENSBTAT00000000721": 1, "P05632": 5, "ENSBTAT00000085877": 1, "P03929": 5, "ENSBTAT00000060553": 1, "A0A3Q1MP66": 5, "ENSBTAT00000072644": 1, "P00847": 5, "ENSBTAT00000060539": 1, "Q3ZC75": 5, "ENSBTAT00000003832": 1, "P13620": 5, "ENSBTAT00000074726": 1, "A0A3Q1M7G3": 5, "ENSBTAT00000077018": 3, "A0A3Q1MCR1": 5, "A0A3Q1N4G2": 5, "Q00361": 5, "ENSBTAT00000023255": 1, "A0A0N4STN0": 5, "ENSBTAT00000009643": 1, "A0A452DI29": 5, "ENSBTAT00000007538": 1, "P32876": 5, "ENSBTAT00000024402": 1, "P13621": 5, "ENSBTAT00000024326": 1, "species_10087633": 18, "reaction_10052963": 3, "species_10052929": 2, "ENSBTAT00000027868": 2, "species_10052959": 93, "A0A3Q1MH45": 5, "ENSBTAT00000017703": 1, "F6Q087": 5, "ENSBTAT00000004656": 1, "species_10052961": 94, "E1BEK9": 4, "reaction_10083789": 3, "species_10083783": 4, "species_10083785": 5, "G3MZS2": 4, "ENSBTAT00000063750": 1, "E1BDP0": 4, "ENSBTAT00000023907": 1, "F1MJL8": 5, "ENSBTAT00000053062": 2, "species_10083787": 7, "reaction_10083793": 2, "species_10083791": 4, "reaction_10084356": 3, "species_10083779": 2, "species_10084354": 4, "reaction_10087862": 3, "species_10087858": 4, "A0A3Q1N1G2": 6, "ENSBTAT00000067627": 2, "A0A3Q1M163": 6, "ENSBTAT00000074335": 2, "species_10087860": 5, "reaction_10087997": 4, "species_10087908": 6, "Q32S26": 5, "ENSBTAT00000014704": 1, "species_10056568": 2, "species_10087995": 5, "reaction_10087900": 4, "species_10087887": 5, "species_10087897": 5, "reaction_10087889": 3, "species_10084945": 4, "reaction_10087910": 3, "species_10087906": 3, "reaction_10088006": 5, "species_10088001": 5, "species_10088003": 4, "species_427486": 1, "reaction_10088012": 3, "species_10088010": 3, "reaction_10086231": 3, "species_10086227": 2, "ENSBTAT00000019489": 2, "species_10086229": 3, "E1BPV9": 2, "reaction_10086587": 5, "species_10086579": 4, "species_10086584": 2, "reaction_10088490": 5, "species_10088485": 2, "species_10088487": 2, "reaction_10086589": 3, "species_10086577": 3, "reaction_10084947": 3, "species_10084939": 2, "reaction_10088482": 2, "species_10088478": 2, "species_10088480": 2, "reaction_10086581": 3, "reaction_10040059": 3, "species_10040054": 7, "A0A3Q1LY33": 16, "ENSBTAT00000085991": 1, "A0A3Q1M1J3": 16, "ENSBTAT00000071469": 1, "Q2TBV1": 16, "ENSBTAT00000014278": 1, "A6QNK6": 3, "ENSBTAT00000002682": 1, "Q2KI86": 16, "ENSBTAT00000008174": 1, "Q3SZ11": 16, "ENSBTAT00000017525": 1, "species_10040050": 4, "F1MFW1": 3, "ENSBTAT00000024392": 1, "E1BG06": 3, "ENSBTAT00000017599": 1, "E1BB72": 3, "ENSBTAT00000025568": 1, "species_10040056": 10, "reaction_10040955": 4, "species_10040945": 5, "species_10040952": 4, "reaction_10040961": 3, "species_10040959": 3, "reaction_10040967": 2, "species_10040965": 4, "reaction_10085313": 5, "species_10060424": 2, "reaction_10083179": 3, "species_10083175": 5, "E1BFF9": 3, "ENSBTAT00000020327": 1, "E1BJZ4": 3, "ENSBTAT00000004036": 1, "A0A3Q1MPM7": 3, "ENSBTAT00000082501": 1, "F1MUW6": 3, "ENSBTAT00000046850": 1, "species_10083141": 6, "Q1RMQ3": 4, "ENSBTAT00000006825": 2, "Q32LJ2": 5, "ENSBTAT00000009858": 1, "Q2YDM1": 5, "ENSBTAT00000015767": 1, "species_10083177": 9, "reaction_10083149": 3, "species_10083119": 2, "species_10083147": 3, "species_10083128": 5, "reaction_10083340": 4, "species_10083331": 10, "Q5EA50": 4, "ENSBTAT00000074576": 1, "species_10083333": 6, "species_10083337": 3, "reaction_10083342": 3, "species_10083323": 7, "reaction_10083187": 3, "species_10083183": 2, "ENSBTAT00000065986": 2, "species_10083135": 4, "species_10083185": 4, "A0A3Q1M9K7": 2, "reaction_10083143": 3, "reaction_10083451": 3, "species_10060581": 4, "species_10083439": 4, "A0A3Q1LM77": 4, "ENSBTAT00000084376": 1, "A0A3Q1M9S8": 4, "ENSBTAT00000086938": 1, "A0A3Q1LS50": 4, "ENSBTAT00000086695": 1, "species_10083449": 7, "reaction_10083425": 3, "species_10083421": 2, "A0A3Q1MQ84": 4, "ENSBTAT00000084706": 2, "species_10083423": 4, "reaction_10083056": 3, "species_10082114": 8, "E1BK29": 4, "ENSBTAT00000007999": 1, "F1MQ89": 4, "ENSBTAT00000027073": 1, "A0A452DKB6": 4, "ENSBTAT00000045677": 1, "E1BGA6": 4, "ENSBTAT00000023803": 1, "F1N5R4": 4, "ENSBTAT00000002179": 1, "Q3MHG0": 4, "ENSBTAT00000017269": 1, "species_10083052": 7, "F1MDA6": 3, "ENSBTAT00000027499": 1, "E1BIQ3": 3, "ENSBTAT00000005055": 1, "A0A3Q1LTE3": 3, "ENSBTAT00000075149": 1, "species_10083054": 13, "reaction_10083458": 2, "species_10083455": 6, "reaction_10083767": 3, "species_10083763": 5, "E1BJ06": 3, "ENSBTAT00000017437": 1, "A0A3Q1M591": 3, "ENSBTAT00000073539": 1, "species_10083765": 11, "reaction_10065827": 3, "species_10065823": 2, "ENSBTAT00000045309": 2, "species_1297302": 2, "species_10065825": 3, "F1MZM9": 2, "reaction_10047292": 3, "species_10047270": 5, "species_10047288": 3, "species_10047290": 7, "reaction_10060207": 5, "species_174369": 5, "species_1614518": 2, "species_10060204": 3, "F1MEW4": 2, "ENSBTAT00000087445": 1, "reaction_10060231": 6, "species_936714": 3, "species_10060225": 6, "A0A3Q1M2L1": 2, "ENSBTAT00000005788": 1, "reaction_10060275": 5, "species_1614585": 1, "species_10060272": 3, "A0A452DHV7": 2, "ENSBTAT00000002916": 1, "reaction_10057032": 5, "species_353106": 2, "species_1237165": 2, "species_83951": 2, "species_10057029": 2, "Q3MHF7": 2, "ENSBTAT00000048509": 1, "reaction_10057023": 6, "species_1237176": 1, "species_1237155": 1, "species_10057020": 3, "Q0VD27": 2, "ENSBTAT00000019702": 1, "reaction_10057684": 3, "species_1237107": 1, "species_10057011": 2, "ENSBTAT00000003273": 1, "reaction_10090681": 4, "species_10090677": 4, "A0A3Q1M9D2": 2, "ENSBTAT00000069079": 3, "Q95108": 2, "species_10089847": 6, "species_1655881": 2, "reaction_10089850": 5, "species_9012724": 1, "species_9012592": 3, "species_1614595": 3, "reaction_10090013": 5, "species_9013199": 3, "species_9013191": 3, "reaction_10060252": 5, "species_1614532": 4, "reaction_10060255": 6, "reaction_10090015": 5, "species_9013543": 1, "reaction_10090679": 3, "species_10090669": 3, "reaction_10060361": 7, "species_1614538": 3, "species_10060358": 2, "ENSBTAT00000023735": 1, "reaction_10060216": 6, "species_10060213": 3, "Q3MHX0": 2, "ENSBTAT00000008101": 1, "reaction_10060250": 7, "species_10060239": 2, "ENSBTAT00000013690": 2, "species_10060241": 2, "species_10060247": 3, "Q3T094": 2, "ENSBTAT00000005747": 1, "reaction_10060264": 4, "species_1614519": 1, "species_10060261": 3, "A0A3Q1MCZ5": 2, "ENSBTAT00000079843": 1, "reaction_10060234": 4, "species_1614582": 1, "reaction_10090671": 4, "reaction_10083204": 5, "species_6814151": 1, "species_1655445": 1, "species_10083201": 3, "G3MZK0": 2, "ENSBTAT00000064438": 1, "reaction_10060228": 4, "species_1614594": 1, "reaction_10089959": 5, "species_9013207": 1, "species_10089956": 2, "ENSBTAT00000043317": 1, "reaction_10077124": 5, "species_4789070": 1, "species_10077121": 3, "F1N4C6": 2, "ENSBTAT00000048928": 1, "reaction_10078575": 5, "species_6797917": 1, "species_6797920": 1, "species_10078572": 3, "A0A3Q1MR10": 2, "ENSBTAT00000075705": 1, "reaction_10078582": 5, "species_6798162": 1, "species_6798194": 1, "species_10078579": 2, "ENSBTAT00000013227": 1, "reaction_10044844": 5, "species_353113": 3, "species_10044841": 2, "ENSBTAT00000006978": 1, "reaction_10044851": 7, "species_10044848": 2, "ENSBTAT00000054971": 1, "reaction_10033778": 4, "reaction_10033788": 9, "species_508182": 5, "species_508187": 5, "CHEBI:28654": 1, "CHEBI:17865": 1, "CHEBI:16530": 1, "species_10033785": 2, "A0A3Q1ML78": 2, "ENSBTAT00000086973": 1, "reaction_10033806": 7, "species_70772": 2, "species_70784": 2, "species_10033803": 2, "A0A3Q1M9N4": 2, "ENSBTAT00000068139": 1, "reaction_10051185": 11, "species_70836": 3, "species_70829": 2, "species_10033812": 2, "O02691": 2, "ENSBTAT00000023642": 1, "reaction_10033824": 5, "species_10033821": 3, "Q29RZ0": 2, "ENSBTAT00000017122": 1, "reaction_10033797": 5, "species_70715": 1, "species_70744": 1, "species_10033794": 3, "A0A452DI40": 2, "ENSBTAT00000005782": 1, "reaction_10052027": 4, "species_33179": 2, "species_10052024": 3, "E1BPE1": 2, "ENSBTAT00000007525": 1, "reaction_10052043": 7, "species_29970": 2, "species_893615": 1, "species_8939576": 3, "CHEBI:55528": 1, "CHEBI:43580": 1, "reaction_10033979": 5, "species_34351": 2, "species_30487": 2, "species_10033976": 2, "A0A3Q1MB81": 2, "ENSBTAT00000069075": 1, "reaction_10052030": 5, "species_893607": 1, "species_893617": 1, "species_10033856": 3, "A0A3Q1LKR3": 2, "ENSBTAT00000085694": 1, "reaction_10033969": 8, "species_10033966": 2, "ENSBTAT00000073847": 1, "reaction_10085381": 3, "reaction_10033988": 4, "species_36027": 1, "species_10033985": 3, "A0A452DIN3": 2, "ENSBTAT00000006132": 1, "reaction_10041894": 4, "species_10041891": 3, "A0A3Q1LFW8": 2, "ENSBTAT00000070085": 1, "reaction_10090155": 4, "species_9014643": 2, "species_10090152": 2, "A5PKH5": 2, "ENSBTAT00000011776": 1, "reaction_10090162": 4, "species_10090159": 2, "ENSBTAT00000016718": 1, "reaction_10065455": 6, "species_5359016": 1, "species_5357697": 1, "species_5357660": 1, "species_5359011": 1, "species_10065452": 2, "A2VDS1": 2, "ENSBTAT00000013719": 1, "reaction_10054601": 5, "species_936706": 2, "species_10054598": 3, "Q2KHU0": 2, "ENSBTAT00000017392": 1, "reaction_10054620": 6, "species_977329": 2, "species_10054617": 2, "A0A140T866": 2, "ENSBTAT00000008907": 1, "reaction_10090172": 7, "species_376186": 2, "species_10090169": 4, "A0JNI4": 2, "ENSBTAT00000005532": 1, "reaction_10090175": 5, "reaction_10054611": 5, "species_10054608": 2, "A0A3S5ZPF7": 2, "ENSBTAT00000018554": 1, "reaction_10086371": 3, "species_8932979": 1, "species_10086368": 3, "A4FUZ5": 2, "ENSBTAT00000002833": 1, "A0A3Q1LF32": 2, "ENSBTAT00000072137": 1, "reaction_10090647": 5, "reaction_10051165": 9, "species_31339": 1, "species_10051162": 2, "Q2KJH7": 2, "ENSBTAT00000015703": 1, "reaction_10077453": 6, "species_35305": 1, "species_10077450": 2, "Q58D08": 2, "ENSBTAT00000022364": 1, "reaction_10087455": 6, "species_10087452": 3, "Q0VCE9": 2, "ENSBTAT00000004262": 1, "F1N0M1": 2, "ENSBTAT00000023262": 1, "reaction_10052046": 5, "species_893598": 1, "reaction_10077444": 6, "species_113590": 1, "species_10077441": 2, "Q17QJ7": 2, "ENSBTAT00000000047": 1, "reaction_10077864": 5, "species_6788606": 1, "species_10077861": 2, "ENSBTAT00000067508": 1, "reaction_10077435": 5, "species_5693325": 2, "species_6783877": 1, "species_10077432": 2, "ENSBTAT00000010444": 1, "reaction_10045036": 9, "species_113577": 2, "species_70951": 4, "species_10045033": 2, "ENSBTAT00000077809": 1, "reaction_10051198": 9, "species_508531": 2, "reaction_10076261": 6, "species_5693311": 1, "species_10076258": 2, "ENSBTAT00000012972": 1, "reaction_10033997": 5, "species_113545": 1, "species_113543": 1, "species_10033994": 2, "Q2HJ74": 2, "ENSBTAT00000007338": 1, "reaction_10042847": 5, "species_29916": 3, "species_200351": 2, "species_10042844": 2, "Q9TTK8": 2, "ENSBTAT00000009871": 1, "reaction_10034004": 6, "species_30401": 1, "species_10034001": 2, "ENSBTAT00000005375": 1, "reaction_10042838": 5, "species_10042835": 2, "Q5EA61": 2, "ENSBTAT00000050490": 1, "reaction_10066232": 3, "species_10066224": 3, "A1A4I7": 2, "ENSBTAT00000046067": 1, "reaction_10084767": 3, "species_10065958": 6, "F1MTH0": 4, "ENSBTAT00000001283": 1, "F1MGK7": 4, "ENSBTAT00000061078": 1, "species_10084763": 2, "F1MCB3": 3, "ENSBTAT00000024268": 1, "species_10084765": 5, "reaction_10091583": 4, "species_10065970": 2, "ENSBTAT00000067569": 2, "reaction_10066206": 4, "species_10066203": 2, "ENSBTAT00000080053": 1, "reaction_10066270": 5, "species_10066267": 2, "ENSBTAT00000027774": 1, "reaction_10066289": 5, "species_2889081": 3, "species_8953505": 3, "species_2889062": 3, "species_10066286": 2, "ENSBTAT00000085969": 1, "reaction_10066227": 4, "reaction_10066034": 5, "species_2731008": 1, "species_74722": 1, "species_10066031": 3, "G3N3A9": 2, "ENSBTAT00000064202": 1, "E1BK15": 2, "ENSBTAT00000027587": 1, "reaction_10066004": 4, "species_1606834": 1, "species_10066001": 3, "A0A3Q1MQ38": 2, "ENSBTAT00000082890": 1, "A0A3Q1N2G9": 2, "ENSBTAT00000077727": 1, "species_2730676": 1, "reaction_10066199": 3, "species_10066196": 4, "E1BLQ0": 2, "ENSBTAT00000012099": 1, "E1BEP9": 2, "ENSBTAT00000017615": 1, "E1B792": 2, "ENSBTAT00000049019": 1, "reaction_10091542": 3, "species_10091540": 3, "reaction_10066282": 5, "species_2892454": 1, "species_10066279": 2, "ENSBTAT00000035648": 2, "reaction_10065965": 6, "species_2672379": 1, "species_2672383": 1, "species_10065963": 2, "ENSBTAT00000027364": 1, "reaction_10066021": 4, "species_10066018": 4, "A0A3Q1LL71": 2, "ENSBTAT00000082451": 1, "G3N0G4": 2, "ENSBTAT00000065331": 1, "F1MJ95": 2, "ENSBTAT00000020495": 1, "reaction_10066277": 3, "species_10066274": 2, "reaction_10065991": 4, "species_10065988": 6, "A0A3Q1MCG6": 2, "A0A3Q1LNC2": 2, "ENSBTAT00000071379": 1, "A0A3Q1MUE0": 2, "ENSBTAT00000078140": 1, "reaction_10049035": 4, "species_10049028": 6, "species_10049032": 6, "reaction_10091701": 4, "species_10091699": 3, "reaction_10049014": 4, "species_10049009": 7, "species_10049011": 7, "reaction_10048059": 3, "species_10048055": 4, "F1MUF6": 9, "ENSBTAT00000032332": 2, "species_10048049": 2, "ENSBTAT00000083796": 2, "species_10048057": 4, "A0A3Q1LN46": 2, "reaction_10048045": 3, "species_140648": 1, "species_10048041": 10, "E1BIA5": 3, "ENSBTAT00000084008": 1, "E1BQ10": 3, "ENSBTAT00000015083": 1, "A2VDQ6": 3, "ENSBTAT00000081011": 1, "F1MW29": 3, "ENSBTAT00000020042": 1, "A0A3Q1MB78": 3, "ENSBTAT00000075672": 1, "E1BF53": 3, "ENSBTAT00000031089": 1, "Q08DJ5": 3, "ENSBTAT00000031090": 1, "G3MZM2": 3, "ENSBTAT00000065042": 1, "species_10048043": 10, "reaction_10048348": 2, "species_10048344": 2, "A0A3Q1M7P7": 4, "ENSBTAT00000070841": 2, "species_10048346": 2, "reaction_10048065": 2, "species_10048061": 4, "species_10048063": 3, "reaction_10048334": 3, "species_10048053": 3, "species_10048330": 2, "species_10048332": 3, "reaction_10048352": 3, "species_10042235": 2, "ENSBTAT00000070790": 2, "species_10048350": 3, "A0A3Q1MRJ9": 2, "reaction_10048342": 3, "species_10048338": 2, "species_10048336": 2, "species_10048340": 3, "reaction_10049335": 2, "reaction_10044043": 3, "species_10044014": 7, "species_10044041": 3, "reaction_10049290": 5, "species_10049037": 3, "species_10040563": 3, "species_10049287": 2, "reaction_10049283": 3, "species_10049281": 2, "reaction_10044018": 3, "species_10044016": 3, "reaction_10049364": 4, "species_10044026": 3, "reaction_10085323": 5, "species_8869214": 1, "species_8869207": 1, "species_10085320": 2, "ENSBTAT00000006727": 1, "reaction_10048182": 3, "species_10037602": 4, "reaction_10072426": 5, "species_10072421": 6, "A0A3Q1LHY8": 3, "ENSBTAT00000075339": 1, "A0A3Q1M6P5": 3, "ENSBTAT00000067242": 1, "species_10072423": 5, "species_10072399": 4, "reaction_10072401": 5, "species_10072322": 4, "reaction_10072326": 3, "species_5623403": 2, "species_10072324": 4, "reaction_10072475": 3, "species_10072451": 13, "Q0IIM2": 4, "ENSBTAT00000013306": 1, "F1MU26": 5, "ENSBTAT00000032389": 2, "E1BHJ5": 5, "ENSBTAT00000008587": 2, "Q1JQ97": 5, "ENSBTAT00000010013": 2, "F1N4X0": 5, "ENSBTAT00000042964": 2, "A6QLF9": 5, "ENSBTAT00000014216": 2, "G3N2W1": 5, "ENSBTAT00000064380": 2, "E1BN34": 5, "ENSBTAT00000026844": 2, "F1MB52": 5, "ENSBTAT00000006505": 2, "species_10072467": 12, "species_10072473": 9, "reaction_10072435": 9, "species_10072245": 2, "species_10072229": 2, "species_10072257": 2, "species_10072241": 2, "species_10072253": 2, "species_10072237": 2, "species_10072249": 2, "species_10072233": 2, "species_10072259": 10, "reaction_10072453": 4, "species_10072449": 2, "species_10072441": 3, "reaction_10057569": 3, "species_10057566": 34, "Q4PJK1": 2, "ENSBTAT00000024576": 1, "A2VDT0": 2, "ENSBTAT00000019888": 1, "E1B7K3": 2, "ENSBTAT00000064709": 1, "F1MLD6": 2, "ENSBTAT00000022142": 1, "F1MTJ1": 2, "ENSBTAT00000009938": 1, "F1N0E8": 2, "ENSBTAT00000010960": 1, "G3N1T8": 2, "ENSBTAT00000065475": 1, "F1MKB0": 2, "ENSBTAT00000020543": 1, "E1B9N0": 2, "ENSBTAT00000021458": 1, "A0A3Q1MFH2": 2, "ENSBTAT00000086274": 1, "A0A3Q1MPE6": 2, "ENSBTAT00000074581": 1, "E1BDC5": 3, "ENSBTAT00000039169": 1, "F1ML52": 2, "ENSBTAT00000022193": 1, "F1MJA9": 3, "ENSBTAT00000018162": 1, "E1BCM0": 2, "ENSBTAT00000004406": 1, "F1MC54": 2, "ENSBTAT00000046307": 1, "F1MP51": 2, "ENSBTAT00000015122": 1, "F1MPV7": 2, "ENSBTAT00000010214": 1, "E1BKI8": 2, "ENSBTAT00000011681": 1, "F1N553": 2, "ENSBTAT00000007132": 1, "A0A3Q1M6H7": 2, "ENSBTAT00000071160": 1, "A4FV89": 2, "ENSBTAT00000028357": 1, "F1MXZ4": 2, "ENSBTAT00000011219": 1, "E1BII8": 2, "ENSBTAT00000023770": 1, "E1B760": 2, "ENSBTAT00000025668": 1, "E1BLH0": 2, "ENSBTAT00000005335": 1, "F1MDM5": 2, "ENSBTAT00000017003": 1, "E1BMA2": 2, "ENSBTAT00000022102": 1, "reaction_10057365": 3, "species_10057362": 3, "E1BGY2": 2, "ENSBTAT00000011376": 1, "F1N467": 2, "ENSBTAT00000014706": 1, "reaction_10057665": 3, "species_10057662": 2, "F1MW24": 2, "ENSBTAT00000020046": 1, "reaction_10057656": 3, "species_10057653": 3, "G3N1D1": 2, "ENSBTAT00000063834": 1, "reaction_10057682": 3, "species_10057679": 3, "Q8HZT2": 2, "ENSBTAT00000013646": 1, "E1BEH1": 2, "ENSBTAT00000030656": 1, "reaction_10057616": 3, "species_10057613": 2, "G3N1Q6": 2, "ENSBTAT00000065420": 1, "reaction_10090498": 8, "species_9027049": 1, "species_10090495": 6, "reaction_10084300": 4, "species_10084266": 2, "ENSBTAT00000071362": 2, "species_10084295": 2, "species_10084297": 2, "species_10045642": 2, "reaction_10083113": 5, "species_163579": 2, "species_8876730": 4, "species_216762": 3, "species_10083110": 2, "ENSBTAT00000026745": 1, "reaction_10085994": 3, "species_10085990": 3, "species_8848047": 1, "species_10085992": 4, "reaction_10086026": 5, "species_8876704": 4, "species_10086023": 2, "ENSBTAT00000033962": 1, "reaction_10086557": 5, "species_10086554": 2, "ENSBTAT00000056670": 1, "reaction_10086002": 4, "species_10085998": 3, "ENSBTAT00000085568": 2, "species_10086000": 4, "A0A3Q1LT67": 2, "reaction_10086004": 3, "reaction_10044020": 3, "species_10037447": 2, "ENSBTAT00000065426": 2, "species_10037453": 2, "species_10037455": 4, "G3MX19": 7, "reaction_10049300": 4, "species_10037463": 2, "species_10037465": 5, "reaction_10040521": 3, "species_10040517": 2, "ENSBTAT00000033975": 2, "species_10040513": 4, "species_10040519": 7, "Q0P5A5": 5, "reaction_10040542": 3, "species_10040537": 7, "A5PKM2": 9, "ENSBTAT00000011001": 3, "species_10040539": 10, "reaction_10040576": 2, "species_10040572": 2, "species_10040574": 2, "reaction_10040503": 2, "species_10040501": 2, "reaction_10033512": 3, "species_10033414": 2, "species_10033508": 2, "species_10033510": 3, "reaction_10033466": 3, "species_10033462": 4, "E1BIF0": 3, "ENSBTAT00000009882": 1, "Q3SZN5": 3, "ENSBTAT00000000316": 1, "A6QQ14": 3, "ENSBTAT00000047798": 1, "species_68419": 1, "species_10033464": 4, "reaction_10087385": 4, "species_10087381": 2, "species_10087383": 5, "reaction_10056616": 6, "species_10056566": 5, "species_10056614": 2, "species_10056599": 6, "reaction_10057816": 3, "species_10056564": 3, "species_10057814": 7, "reaction_10056602": 6, "reaction_10057821": 4, "species_10057818": 5, "reaction_10087487": 5, "species_10087392": 7, "species_10087465": 6, "species_10087484": 1, "reaction_10087503": 2, "species_10087491": 6, "species_10087501": 5, "reaction_10087394": 3, "species_10087390": 3, "reaction_10065794": 5, "species_10065782": 5, "F1N3G4": 3, "ENSBTAT00000019603": 1, "F1MH70": 3, "ENSBTAT00000017174": 1, "species_10065792": 5, "species_2529006": 1, "reaction_10035745": 2, "species_10035737": 3, "species_10035743": 3, "reaction_10035747": 2, "species_10035731": 2, "species_10035739": 2, "reaction_10074692": 2, "species_10074688": 2, "species_10074690": 3, "F6R5E4": 2, "reaction_10074695": 4, "reaction_10051465": 3, "species_10051445": 5, "E1BMQ3": 5, "ENSBTAT00000003380": 1, "A5D7N9": 5, "ENSBTAT00000022106": 1, "E1BAL2": 5, "ENSBTAT00000014256": 1, "species_10051395": 14, "A0A3Q1M302": 6, "ENSBTAT00000068526": 1, "A8WFK5": 6, "ENSBTAT00000048435": 1, "F1MLG9": 6, "ENSBTAT00000061053": 1, "Q5EA18": 6, "ENSBTAT00000009094": 1, "Q2NKU0": 9, "ENSBTAT00000005369": 1, "Q08DW5": 6, "ENSBTAT00000027600": 1, "E1BAK5": 6, "ENSBTAT00000001748": 1, "G3MXW4": 6, "ENSBTAT00000064627": 1, "Q3ZBK8": 6, "ENSBTAT00000032953": 1, "A7YWP8": 6, "ENSBTAT00000068875": 1, "Q2TBR7": 9, "ENSBTAT00000017996": 1, "A0A3Q1LTH6": 6, "ENSBTAT00000039939": 1, "species_10051453": 18, "reaction_10051451": 5, "species_10051447": 28, "G5E613": 5, "ENSBTAT00000049496": 1, "E1BB33": 5, "ENSBTAT00000042677": 1, "A7MBG8": 5, "ENSBTAT00000027964": 1, "species_10051335": 3, "A0A3Q1LP30": 3, "ENSBTAT00000083436": 1, "species_10051431": 8, "species_10051449": 19, "reaction_10051461": 4, "species_10035218": 1, "species_10051459": 28, "species_10035105": 1, "reaction_10051463": 3, "species_10051457": 11, "reaction_10058792": 5, "reaction_10057070": 5, "reaction_10063560": 4, "species_10043501": 4, "species_10060344": 5, "A0A3Q1M285": 6, "ENSBTAT00000072870": 1, "F1ML06": 6, "ENSBTAT00000018956": 1, "species_10063558": 5, "species_10060342": 3, "reaction_10063562": 2, "species_10060328": 3, "species_10060330": 4, "reaction_10060346": 2, "species_10060332": 5, "reaction_10063564": 3, "reaction_10090604": 4, "species_10090597": 2, "ENSBTAT00000052816": 3, "species_10090599": 2, "species_10090601": 2, "reaction_10037293": 3, "species_10037287": 5, "F1MD58": 5, "ENSBTAT00000008706": 1, "Q2NL36": 4, "ENSBTAT00000005496": 3, "species_10037229": 8, "species_10037291": 4, "reaction_10090504": 4, "species_9027547": 1, "reaction_10090506": 4, "species_9027614": 1, "reaction_10090508": 4, "species_9027622": 1, "reaction_10090510": 4, "species_9028280": 1, "reaction_10075037": 6, "species_10075030": 2, "species_10075034": 2, "ENSBTAT00000026521": 1, "reaction_10074798": 4, "species_10074795": 7, "species_10074789": 7, "reaction_10076339": 4, "species_10076336": 7, "species_10075051": 7, "reaction_10060476": 5, "species_10060456": 2, "ENSBTAT00000047316": 2, "reaction_10083369": 5, "species_2239407": 1, "species_6814794": 1, "species_10083366": 2, "ENSBTAT00000015375": 1, "reaction_10083211": 5, "species_10083208": 2, "ENSBTAT00000084401": 1, "reaction_10082931": 2, "species_10082927": 2, "ENSBTAT00000003561": 2, "species_10082929": 3, "reaction_10083092": 5, "species_6810408": 4, "species_10083089": 3, "reaction_10082934": 5, "reaction_10060569": 5, "species_10060566": 13, "F1MDQ5": 3, "ENSBTAT00000003878": 1, "E1B8D1": 3, "ENSBTAT00000043102": 1, "F1MBU9": 2, "ENSBTAT00000017388": 1, "reaction_10060473": 5, "species_10060470": 4, "reaction_10082136": 3, "species_10082132": 3, "ENSBTAT00000004852": 2, "species_10082128": 2, "ENSBTAT00000050192": 2, "species_10082134": 3, "F1ME94": 3, "A7MB43": 4, "reaction_10060600": 5, "species_1806224": 3, "species_10060532": 5, "A0A3Q1LYK5": 4, "ENSBTAT00000069408": 2, "reaction_10085784": 3, "species_10085767": 3, "ENSBTAT00000000317": 4, "species_1806200": 4, "species_10085782": 3, "F6R352": 2, "reaction_10060572": 5, "species_1806276": 6, "reaction_10060595": 5, "species_10060592": 3, "A6QNM5": 3, "ENSBTAT00000015257": 1, "E1BLB5": 4, "ENSBTAT00000022635": 2, "reaction_10085780": 5, "species_10085777": 2, "species_10085773": 3, "species_10044855": 2, "ENSBTAT00000000488": 1, "reaction_10060535": 5, "reaction_10082152": 5, "species_10082149": 5, "reaction_10082155": 5, "reaction_10060429": 5, "reaction_10060461": 5, "species_10060458": 5, "F1MK34": 2, "A6QLN5": 2, "ENSBTAT00000002604": 1, "reaction_10085775": 2, "reaction_10060590": 5, "species_10060585": 5, "ENSBTAT00000079052": 1, "reaction_10085697": 3, "species_10085693": 2, "E1B7V8": 3, "ENSBTAT00000061135": 1, "species_10085695": 3, "reaction_10060579": 5, "species_10060576": 6, "reaction_10082147": 3, "species_10060526": 2, "species_10082145": 3, "reaction_10060514": 5, "species_10060511": 5, "reaction_10060550": 5, "species_10060547": 7, "reaction_10083800": 5, "species_8849959": 4, "species_8849958": 4, "species_1806205": 2, "species_1806259": 3, "species_10083797": 2, "ENSBTAT00000029059": 1, "reaction_10060588": 5, "reaction_10060558": 5, "reaction_10060574": 5, "species_1806199": 3, "reaction_10060501": 5, "reaction_10060518": 5, "reaction_10060614": 5, "reaction_10060611": 5, "species_1806230": 2, "species_1806217": 5, "species_10060608": 2, "A0A3Q1MHQ7": 2, "ENSBTAT00000081928": 1, "reaction_10060483": 5, "species_1806165": 1, "species_10060480": 2, "ENSBTAT00000001784": 1, "reaction_10060498": 5, "species_10060495": 5, "reaction_10060597": 5, "species_1524146": 2, "reaction_10060516": 5, "species_1806159": 1, "reaction_10085843": 3, "species_8874484": 3, "species_8874460": 3, "species_10085840": 2, "A0A3Q1LVF0": 2, "ENSBTAT00000072298": 1, "reaction_10040152": 5, "species_176575": 1, "species_176501": 1, "species_158466": 17, "species_10040149": 4, "Q3ZC30": 6, "ENSBTAT00000015862": 1, "E1BG19": 5, "ENSBTAT00000031917": 1, "F1N0S6": 5, "ENSBTAT00000028234": 1, "reaction_10040120": 5, "species_176555": 1, "species_10040087": 4, "reaction_10040122": 5, "species_176565": 1, "reaction_10040157": 5, "species_176566": 1, "species_176500": 1, "species_10040154": 4, "A0A3Q1MP36": 3, "ENSBTAT00000072780": 1, "F1MBP4": 3, "ENSBTAT00000003629": 1, "P50227": 5, "ENSBTAT00000011388": 1, "reaction_10076799": 5, "species_5695960": 1, "species_5695950": 2, "species_10076796": 2, "ENSBTAT00000024782": 1, "reaction_10038320": 5, "species_158847": 1, "species_158859": 1, "species_10038228": 5, "reaction_10040112": 5, "species_176665": 1, "species_10040109": 3, "A1A4N6": 4, "ENSBTAT00000063187": 1, "reaction_10040147": 5, "species_176600": 1, "species_10040144": 3, "reaction_10040115": 5, "species_176492": 1, "species_10040075": 2, "reaction_10040117": 5, "species_176667": 1, "species_176564": 1, "species_10040095": 8, "F1MZX9": 2, "ENSBTAT00000011474": 1, "reaction_10038231": 5, "species_158469": 1, "species_158472": 1, "reaction_10088617": 5, "species_10088606": 2, "ENSBTAT00000043559": 2, "species_10088610": 2, "reaction_10040136": 5, "species_176496": 1, "species_10040133": 5, "reaction_10040107": 5, "species_176617": 2, "species_176502": 1, "species_10040104": 3, "reaction_10038318": 5, "species_158858": 1, "species_158850": 1, "reaction_10040129": 5, "species_10040126": 2, "ENSBTAT00000005311": 1, "reaction_10040131": 5, "species_176478": 1, "species_176618": 1, "reaction_10040098": 5, "species_176486": 1, "species_176519": 1, "reaction_10038340": 5, "species_159352": 1, "reaction_10088580": 6, "species_8851226": 3, "species_8953493": 1, "species_10088577": 3, "A0A452DIR7": 2, "ENSBTAT00000020766": 1, "reaction_10050342": 3, "species_450444": 1, "species_10050336": 2, "A0A3Q1M8I4": 3, "ENSBTAT00000075547": 1, "species_10050340": 2, "reaction_10082923": 3, "species_10069400": 3, "ENSBTAT00000066213": 2, "species_10082921": 3, "G3MY31": 4, "reaction_10086155": 3, "species_10086151": 3, "species_10086153": 4, "reaction_10083072": 4, "species_10083070": 5, "reaction_10083077": 5, "species_10083074": 4, "reaction_10090593": 3, "species_10090579": 2, "ENSBTAT00000022338": 2, "species_10090589": 4, "A0A3Q1NBU3": 3, "ENSBTAT00000081070": 1, "species_10090591": 5, "Q08DL6": 2, "reaction_10090770": 3, "species_10090766": 10, "A4FUD4": 3, "ENSBTAT00000026285": 1, "A0A3Q1M1S5": 3, "ENSBTAT00000047447": 1, "A0A3Q1MTZ2": 3, "ENSBTAT00000074727": 1, "Q148K5": 3, "ENSBTAT00000011022": 1, "A0A3Q1MSZ7": 3, "ENSBTAT00000082884": 1, "A6QQZ0": 3, "ENSBTAT00000016739": 1, "A0A452DI69": 3, "ENSBTAT00000009885": 1, "species_10090732": 2, "ENSBTAT00000009921": 2, "species_10090768": 11, "Q3SZD1": 2, "reaction_10039049": 4, "species_10039039": 21, "reaction_10039044": 3, "species_10039041": 20, "reaction_10039047": 5, "reaction_10035417": 7, "reaction_10035374": 11, "species_73911": 4, "species_73909": 5, "species_10035360": 3, "Q02337": 2, "ENSBTAT00000082799": 1, "reaction_10035415": 5, "species_10035412": 2, "A0A3Q1LIX4": 2, "ENSBTAT00000077723": 1, "reaction_10065944": 4, "species_10035617": 4, "A0A3Q1MAN7": 3, "ENSBTAT00000077886": 1, "species_10065942": 3, "species_2466098": 1, "reaction_10035596": 7, "species_10035583": 2, "ENSBTAT00000011564": 1, "species_10035592": 2, "ENSBTAT00000087322": 3, "species_10035594": 3, "P46065": 3, "species_10035590": 4, "reaction_10065808": 5, "species_10065796": 2, "species_2534019": 1, "species_10065799": 2, "species_10065805": 3, "Q9N181": 2, "ENSBTAT00000050460": 1, "F1MZK0": 2, "reaction_10035619": 7, "species_10035601": 2, "species_10035607": 3, "F1MBQ1": 2, "ENSBTAT00000068795": 1, "reaction_10065940": 3, "species_10035588": 2, "reaction_10078600": 3, "species_10078596": 1, "species_10078418": 4, "F1MMZ4": 7, "ENSBTAT00000061495": 1, "F1N119": 7, "ENSBTAT00000026956": 1, "species_10078598": 3, "reaction_10078488": 3, "species_10078484": 3, "A0A3Q1LWK1": 4, "ENSBTAT00000075847": 1, "E1B7S3": 4, "ENSBTAT00000061281": 1, "species_10078486": 5, "reaction_10078522": 3, "species_10078444": 7, "F6Q4B1": 6, "ENSBTAT00000045228": 1, "G3X7N7": 6, "ENSBTAT00000040145": 1, "F1N104": 6, "ENSBTAT00000026987": 1, "species_10078520": 9, "reaction_10078446": 3, "species_10078442": 4, "reaction_10078464": 3, "species_10078458": 5, "A0A3Q1LHC4": 4, "ENSBTAT00000083397": 1, "F1MW19": 4, "ENSBTAT00000001076": 1, "species_10078456": 4, "species_10078462": 4, "reaction_10078466": 3, "species_10045110": 2, "reaction_10078518": 3, "species_10078514": 11, "A0A3Q1MV08": 3, "ENSBTAT00000084157": 1, "E1BBJ2": 3, "ENSBTAT00000006420": 1, "A0A3Q1LRW9": 3, "ENSBTAT00000068330": 1, "species_10043423": 2, "species_10078516": 12, "reaction_10046648": 6, "species_10046644": 3, "species_10046646": 3, "species_10044632": 5, "species_10044626": 5, "reaction_10046623": 3, "species_10044624": 2, "reaction_10046642": 2, "species_10046640": 4, "reaction_10046630": 3, "species_10044630": 2, "reaction_10043885": 3, "species_209767": 2, "species_10043881": 4, "ENSBTAT00000075079": 2, "species_10043883": 4, "A0A3Q1LQ02": 6, "reaction_10043903": 2, "species_10043895": 5, "F1MKV7": 5, "ENSBTAT00000039417": 3, "species_10043901": 4, "reaction_10088926": 3, "reaction_10043984": 3, "species_209906": 1, "species_10043982": 4, "reaction_10088928": 3, "species_10044728": 3, "species_350136": 1, "species_10043899": 2, "reaction_10044739": 3, "species_10044732": 5, "species_10044736": 2, "ENSBTAT00000005988": 1, "reaction_10044741": 3, "species_10044730": 2, "reaction_10043910": 9, "species_350159": 1, "reaction_10040922": 7, "species_191265": 3, "species_191269": 2, "species_10040919": 4, "Q6IE76": 2, "ENSBTAT00000016504": 1, "reaction_10041664": 8, "species_195691": 2, "species_195655": 1, "species_10041661": 3, "ENSBTAT00000072112": 1, "reaction_10041728": 6, "species_196420": 1, "species_10041725": 3, "ENSBTAT00000080856": 1, "reaction_10041671": 3, "species_194691": 2, "species_10041668": 3, "ENSBTAT00000012234": 1, "reaction_10040892": 5, "species_191409": 2, "species_191385": 2, "species_10040889": 4, "P56966": 2, "ENSBTAT00000017376": 1, "reaction_10040924": 4, "reaction_10040895": 5, "species_191324": 2, "reaction_10041502": 7, "species_194657": 2, "species_194661": 1, "species_10041481": 3, "ENSBTAT00000012167": 1, "reaction_10040913": 3, "species_10040910": 3, "A0A140T853": 2, "ENSBTAT00000005323": 1, "reaction_10040881": 8, "species_191309": 1, "species_10040878": 3, "A5D9A8": 2, "ENSBTAT00000007228": 1, "reaction_10088019": 5, "species_8952135": 1, "species_10088016": 2, "ENSBTAT00000014674": 1, "reaction_10041493": 6, "species_194681": 1, "species_194725": 1, "species_194688": 1, "species_194668": 1, "species_194704": 1, "species_10041490": 2, "reaction_10083496": 5, "species_191293": 1, "species_10083493": 2, "A0A3Q1MLP4": 2, "ENSBTAT00000012548": 1, "reaction_10040904": 7, "species_191374": 1, "species_191424": 1, "species_10040901": 2, "A7Z064": 2, "ENSBTAT00000010315": 1, "reaction_10041484": 7, "species_194735": 2, "species_194667": 1, "reaction_10041486": 8, "species_194723": 1, "species_10041474": 3, "ENSBTAT00000003991": 1, "reaction_10081986": 3, "species_6807048": 2, "species_6807054": 2, "reaction_10081988": 8, "species_6807057": 1, "reaction_10081990": 6, "reaction_10041477": 8, "reaction_10038347": 8, "species_194096": 3, "species_194073": 3, "species_192356": 2, "CHEBI:28701": 1, "reaction_10041437": 6, "species_10041428": 2, "ENSBTAT00000014054": 2, "species_192483": 7, "CHEBI:17687": 2, "CHEBI:28865": 2, "CHEBI:36274": 2, "CHEBI:9407": 1, "species_10041430": 8, "A0A452DID8": 4, "CHEBI:16525": 1, "species_10041434": 2, "ENSBTAT00000021363": 1, "reaction_10085806": 4, "species_10085802": 2, "ENSBTAT00000014559": 2, "species_10085804": 4, "A1A4M6": 2, "reaction_10085291": 3, "species_8868399": 2, "species_8868400": 1, "species_10085288": 6, "A0A3Q1LYV2": 2, "ENSBTAT00000083446": 1, "E1BBD8": 2, "ENSBTAT00000017982": 1, "E1BL67": 2, "ENSBTAT00000044841": 1, "A0A3Q1M0E7": 2, "ENSBTAT00000066543": 2, "A0A3Q1MW81": 2, "reaction_10041097": 8, "species_192194": 2, "reaction_10041369": 6, "species_193829": 2, "species_193843": 1, "reaction_10041371": 6, "species_193835": 2, "reaction_10041373": 6, "species_9617026": 1, "reaction_10041375": 6, "species_193830": 2, "reaction_10041377": 6, "species_193842": 1, "reaction_10041208": 7, "species_192013": 2, "species_192096": 2, "reaction_10041179": 8, "species_191968": 2, "species_192161": 1, "reaction_10041210": 6, "species_191980": 2, "species_192030": 1, "reaction_10041308": 5, "reaction_10041310": 8, "species_193436": 1, "species_193387": 2, "reaction_10041104": 8, "species_192078": 1, "species_192201": 2, "reaction_10041170": 6, "species_192064": 2, "species_192087": 1, "reaction_10041301": 5, "species_193442": 2, "species_193459": 1, "species_10041223": 4, "reaction_10041204": 6, "species_192136": 2, "reaction_10041172": 6, "reaction_10041111": 6, "reaction_10041321": 7, "species_193505": 2, "species_193457": 2, "reaction_10041323": 3, "species_193429": 1, "reaction_10041226": 5, "species_192316": 2, "species_192342": 1, "reaction_10041197": 6, "species_192195": 1, "reaction_10041325": 8, "species_193435": 2, "species_193440": 1, "reaction_10041327": 6, "reaction_10041186": 3, "species_192308": 1, "reaction_10041317": 7, "reaction_10041319": 7, "reaction_10085316": 5, "species_8868393": 1, "reaction_10076009": 4, "species_10069573": 2, "ENSBTAT00000080567": 2, "species_10069565": 2, "ENSBTAT00000010319": 2, "species_10076007": 5, "Q2TBN3": 6, "A0A3Q1LPC8": 6, "reaction_10077396": 3, "species_10076069": 9, "species_10077087": 11, "reaction_10077108": 4, "species_10077089": 11, "species_10077106": 11, "reaction_10076071": 5, "species_10076067": 12, "species_5688114": 1, "species_10076065": 8, "reaction_10077016": 5, "species_10077009": 5, "Q1LZ75": 4, "ENSBTAT00000023078": 2, "species_10036653": 3, "species_10077013": 2, "ENSBTAT00000067380": 1, "reaction_10036661": 3, "species_10036657": 2, "ENSBTAT00000046336": 2, "species_10036659": 4, "E1BKV9": 3, "reaction_10037517": 4, "species_10037504": 6, "P02453": 5, "ENSBTAT00000017420": 1, "species_10037514": 8, "reaction_10049071": 2, "species_10049069": 2, "species_10037554": 3, "reaction_10049395": 5, "reaction_10049426": 5, "species_10049418": 4, "species_10049420": 4, "species_10049423": 2, "reaction_10037557": 4, "reaction_10037588": 3, "species_10037586": 7, "reaction_10050630": 3, "species_10050628": 7, "species_10050626": 2, "reaction_10047475": 4, "species_10047470": 9, "species_10047472": 9, "reaction_10049039": 5, "reaction_10047985": 2, "species_10047983": 2, "reaction_10037201": 3, "species_10037197": 2, "species_10037193": 2, "species_10037199": 3, "reaction_10037185": 3, "species_10037181": 2, "ENSBTAT00000027214": 2, "species_10037177": 2, "ENSBTAT00000073946": 2, "species_10037183": 3, "A6QQT5": 2, "E1BNP8": 2, "reaction_10037187": 3, "species_10037108": 3, "G3N172": 4, "ENSBTAT00000063128": 2, "A0A3Q1MA24": 3, "ENSBTAT00000074231": 1, "species_10037098": 2, "ENSBTAT00000006162": 2, "species_10037110": 4, "Q5EAB2": 2, "reaction_10037189": 3, "species_10037135": 2, "species_10037130": 2, "reaction_10037207": 2, "reaction_10081897": 2, "species_10081893": 2, "ENSBTAT00000086118": 3, "species_10081895": 2, "reaction_10037264": 3, "species_10037260": 2, "species_10037262": 3, "reaction_10091186": 2, "species_10037285": 5, "reaction_10049241": 3, "reaction_10049243": 3, "reaction_10049262": 3, "species_10049259": 2, "O77750": 3, "ENSBTAT00000082069": 1, "reaction_10049253": 3, "species_10049250": 2, "P79099": 3, "ENSBTAT00000011024": 1, "reaction_10049271": 3, "species_192438": 3, "species_10049268": 2, "F1N3R5": 4, "ENSBTAT00000026782": 1, "reaction_10051145": 3, "species_10051138": 4, "F1MNJ1": 4, "ENSBTAT00000006790": 1, "reaction_10051148": 3, "species_10051119": 3, "reaction_10051150": 3, "reaction_10051136": 3, "species_10051133": 10, "A0A3S5ZPM1": 2, "ENSBTAT00000026884": 1, "P06624": 2, "ENSBTAT00000013360": 1, "A0A3Q1LWN9": 2, "ENSBTAT00000085930": 1, "reaction_10051141": 3, "reaction_10051143": 3, "reaction_10041050": 3, "species_10041043": 18, "E1BEK3": 4, "ENSBTAT00000027878": 1, "Q2KHW8": 4, "ENSBTAT00000020624": 1, "F1MRW7": 4, "ENSBTAT00000024914": 1, "Q17QA0": 4, "ENSBTAT00000014112": 1, "F1MAW0": 4, "ENSBTAT00000017819": 1, "O18870": 4, "ENSBTAT00000007547": 1, "E1BJG3": 4, "ENSBTAT00000016037": 1, "Q1LZ79": 4, "ENSBTAT00000013582": 1, "Q3ZC10": 4, "ENSBTAT00000010912": 1, "CHEBI:2274": 1, "species_10041031": 19, "CHEBI:1604": 2, "species_10041047": 2, "reaction_10041039": 3, "species_10041035": 2, "ENSBTAT00000076267": 2, "species_10041037": 19, "Q2TBK8": 2, "reaction_10039916": 5, "species_174932": 3, "species_159154": 2, "CHEBI:17688": 1, "species_174918": 3, "CHEBI:63860": 1, "CHEBI:32663": 1, "species_10038333": 4, "ENSBTAT00000076879": 1, "reaction_10076785": 5, "species_5694574": 1, "species_5694569": 1, "species_5694565": 1, "species_10076782": 2, "ENSBTAT00000006038": 1, "reaction_10038336": 5, "species_159160": 2, "species_159149": 1, "reaction_10038338": 5, "reaction_10039749": 7, "species_10039746": 2, "P12378": 2, "ENSBTAT00000019302": 1, "reaction_10040682": 8, "species_189466": 1, "species_10040679": 2, "A0A452DI36": 2, "ENSBTAT00000005380": 1, "species_189444": 3, "reaction_10040654": 6, "species_189411": 1, "species_189480": 1, "species_189478": 2, "species_10040651": 2, "E1BKY9": 2, "ENSBTAT00000005398": 1, "reaction_10040688": 4, "species_190173": 2, "species_10040669": 4, "species_10040686": 4, "reaction_10040672": 5, "species_189489": 1, "species_189464": 2, "reaction_10066416": 6, "species_2162257": 1, "species_2995328": 1, "species_10066413": 2, "ENSBTAT00000020336": 1, "reaction_10040645": 5, "species_189449": 1, "species_10040642": 3, "CHEBI:36319": 1, "Q2KIN5": 2, "ENSBTAT00000007052": 1, "reaction_10040663": 5, "species_189463": 1, "species_10040660": 3, "P56602": 2, "ENSBTAT00000061124": 1, "reaction_10038380": 7, "species_159559": 1, "species_159557": 2, "species_10038377": 2, "A7MBE6": 2, "reaction_10038382": 5, "species_159572": 1, "reaction_10083864": 5, "species_8870906": 2, "species_8870962": 1, "species_10083858": 5, "A0A3Q1LNT1": 2, "ENSBTAT00000085096": 1, "reaction_10083852": 5, "species_8936166": 6, "CHEBI:16039": 1, "species_8851092": 6, "species_10083849": 4, "G3MZH7": 2, "ENSBTAT00000063714": 1, "reaction_10083873": 5, "species_8851224": 6, "CHEBI:18075": 3, "species_8851227": 5, "species_109366": 9, "species_10083870": 4, "A0A3Q1M496": 2, "ENSBTAT00000071190": 1, "reaction_10083889": 5, "species_8851462": 5, "species_8851461": 5, "species_10083886": 4, "Q2KJI4": 2, "ENSBTAT00000081265": 1, "reaction_10083861": 5, "species_8870907": 1, "reaction_10083876": 5, "species_8851233": 5, "reaction_10083926": 5, "species_8851517": 1, "species_8851509": 4, "species_8851513": 1, "species_8851518": 4, "species_10083923": 3, "G3MYV7": 2, "ENSBTAT00000062934": 1, "reaction_10066684": 5, "species_10066681": 2, "reaction_10081541": 4, "species_10081534": 2, "species_10081538": 2, "ENSBTAT00000083405": 1, "reaction_10066737": 3, "species_10066733": 2, "species_10066728": 2, "ENSBTAT00000069634": 2, "species_10066735": 3, "A0A3Q1M5Y5": 2, "reaction_10081877": 5, "species_10081870": 2, "species_10081874": 2, "ENSBTAT00000052840": 1, "reaction_10066724": 4, "species_10066720": 2, "ENSBTAT00000067101": 2, "species_10066722": 5, "A6QLF6": 3, "reaction_10072550": 4, "species_10072547": 4, "reaction_10080811": 3, "species_10080807": 3, "A0A3Q1LWL2": 3, "ENSBTAT00000083195": 1, "A0A3Q1NE67": 3, "ENSBTAT00000082457": 1, "species_10078666": 4, "G3X6J7": 7, "ENSBTAT00000007643": 1, "species_10080809": 5, "reaction_10081530": 3, "species_10081526": 2, "ENSBTAT00000007421": 2, "species_10081528": 3, "E1BLU8": 2, "reaction_10080797": 3, "species_10080793": 2, "ENSBTAT00000070207": 2, "species_10080795": 4, "A0A3Q1M2S9": 2, "reaction_10066764": 3, "species_10066754": 2, "ENSBTAT00000007321": 4, "species_10066760": 2, "species_10066762": 3, "E1BMS9": 2, "reaction_10081889": 2, "species_10081885": 2, "species_10081887": 2, "reaction_10081522": 3, "species_10081518": 2, "ENSBTAT00000077824": 2, "species_10081520": 3, "A0A3Q1MTW2": 2, "reaction_10078474": 3, "species_10078470": 2, "species_10037102": 2, "species_10078472": 3, "reaction_10072571": 4, "species_10072563": 2, "Q5E947": 4, "ENSBTAT00000004751": 1, "species_10072568": 3, "reaction_10072557": 5, "species_10072554": 2, "ENSBTAT00000022146": 1, "reaction_10072591": 3, "species_10072587": 4, "Q58CN8": 4, "ENSBTAT00000042886": 1, "A7MBI2": 4, "ENSBTAT00000034532": 1, "species_10072589": 4, "reaction_10072595": 3, "species_10072593": 9, "reaction_10072614": 3, "species_10072610": 2, "ENSBTAT00000000187": 2, "species_10072612": 6, "Q08E62": 2, "reaction_10053210": 9, "species_10053207": 4, "F1MXW4": 2, "ENSBTAT00000011569": 1, "A0A3Q1M1C8": 2, "ENSBTAT00000073742": 1, "E1BLX8": 2, "ENSBTAT00000026587": 1, "reaction_10053258": 7, "species_947594": 3, "species_947588": 3, "species_10053255": 5, "F1MZ89": 2, "ENSBTAT00000035192": 1, "A0A3Q1MCF3": 2, "ENSBTAT00000082277": 1, "A0A3Q1M082": 2, "ENSBTAT00000075591": 1, "F1N3G6": 2, "ENSBTAT00000021914": 1, "reaction_10076172": 7, "species_1981162": 1, "species_10076169": 2, "ENSBTAT00000009383": 1, "reaction_10076179": 7, "species_5692450": 1, "species_5692484": 1, "species_10076176": 2, "ENSBTAT00000010946": 1, "reaction_10053143": 7, "species_10053140": 3, "A0A3Q1LYD6": 2, "ENSBTAT00000086525": 1, "reaction_10071254": 7, "species_5252122": 1, "species_5252016": 1, "species_10071251": 3, "F1N272": 2, "ENSBTAT00000021694": 1, "A0A3Q1M0A4": 2, "ENSBTAT00000077002": 1, "reaction_10057787": 6, "species_379721": 1, "species_10057762": 7, "Q0VCG0": 4, "ENSBTAT00000044551": 1, "Q05B87": 4, "ENSBTAT00000001725": 1, "Q17QE6": 4, "ENSBTAT00000015648": 1, "species_10057776": 4, "CHEBI:33738": 1, "P00257": 3, "ENSBTAT00000015660": 1, "Q05B51": 3, "ENSBTAT00000013630": 1, "species_10057778": 6, "CHEBI:33739": 2, "species_10057784": 4, "CHEBI:33737": 1, "reaction_10057792": 3, "species_113531": 1, "species_10057790": 5, "reaction_10086272": 5, "species_10086254": 3, "A6QLZ6": 2, "ENSBTAT00000017860": 2, "species_10086264": 3, "Q3SZG8": 3, "ENSBTAT00000079550": 1, "Q2TBG7": 3, "ENSBTAT00000029272": 1, "species_10086252": 2, "species_10086266": 4, "species_10086270": 2, "ENSBTAT00000044111": 1, "reaction_10070682": 3, "species_10070678": 2, "species_10067320": 4, "reaction_10072346": 5, "species_10072328": 7, "species_10072338": 5, "Q08DN8": 2, "ENSBTAT00000013135": 1, "reaction_10070684": 2, "species_10067318": 4, "reaction_10070689": 4, "reaction_10070531": 5, "species_10070524": 4, "species_10070526": 4, "species_10070529": 4, "reaction_10070534": 6, "reaction_10061064": 5, "species_1629731": 2, "species_10060935": 6, "P20456": 2, "ENSBTAT00000015548": 1, "A0A3Q1LZI8": 2, "ENSBTAT00000077982": 1, "reaction_10061067": 5, "species_1629753": 2, "reaction_10060986": 5, "species_1629739": 2, "species_10060509": 2, "reaction_10060938": 5, "species_870330": 1, "reaction_10061134": 5, "species_994123": 3, "species_1629746": 2, "species_10061058": 4, "P21327": 2, "ENSBTAT00000084681": 1, "reaction_10061061": 5, "reaction_10061014": 5, "species_1629769": 1, "reaction_10061046": 5, "reaction_10044666": 7, "species_171095": 1, "species_10044663": 2, "A0A3Q1M833": 2, "ENSBTAT00000085091": 1, "reaction_10074493": 7, "species_5682283": 1, "species_10074490": 2, "ENSBTAT00000004518": 1, "reaction_10046707": 7, "species_382577": 1, "species_382571": 1, "reaction_10058216": 7, "species_1454930": 1, "species_1454919": 1, "species_10058213": 6, "A0A3Q1LZ85": 2, "ENSBTAT00000076899": 1, "E1BNL1": 2, "ENSBTAT00000007685": 1, "F1N4I6": 2, "ENSBTAT00000014417": 1, "F1N3Y6": 2, "ENSBTAT00000026744": 1, "F1MUC1": 2, "reaction_10074360": 7, "species_382539": 1, "species_10074357": 2, "ENSBTAT00000070307": 1, "reaction_10070728": 7, "species_5223341": 1, "species_5223344": 1, "species_10070725": 2, "A0A3Q1LZ87": 2, "ENSBTAT00000070992": 1, "reaction_10057832": 7, "species_1369066": 1, "species_1369027": 1, "species_10057829": 2, "A5D7P7": 2, "ENSBTAT00000027459": 1, "reaction_10046698": 7, "species_10046695": 2, "A0A3Q1MUB7": 2, "ENSBTAT00000085390": 1, "reaction_10058469": 7, "species_1131652": 1, "species_1467459": 1, "species_10058466": 3, "A0A3Q1MB23": 2, "ENSBTAT00000080713": 1, "A0A3Q1LS24": 2, "ENSBTAT00000073046": 1, "reaction_10070743": 3, "species_10070739": 2, "ENSBTAT00000070886": 2, "species_10070741": 5, "A0A3Q1NB13": 2, "reaction_10088584": 3, "species_10088550": 4, "ENSBTAT00000028703": 2, "species_10056555": 2, "species_10088582": 3, "Q08DY6": 7, "reaction_10088554": 3, "species_10056551": 2, "species_10088552": 4, "reaction_10089578": 6, "species_10089554": 2, "ENSBTAT00000013026": 2, "species_10089550": 3, "ENSBTAT00000076903": 2, "species_10066826": 3, "species_10081545": 2, "ENSBTAT00000085264": 2, "species_10089576": 7, "A0A3Q1MS74": 4, "A6H7C4": 3, "E1BJL2": 4, "reaction_10088564": 3, "species_10088560": 3, "E1BKB7": 5, "ENSBTAT00000020143": 1, "A0A3Q1MV00": 5, "ENSBTAT00000069877": 1, "species_10088562": 5, "reaction_10088596": 3, "species_10088592": 6, "E1BMR4": 3, "ENSBTAT00000077318": 1, "A0A3Q1LF83": 3, "ENSBTAT00000077335": 1, "species_10088586": 1, "species_10088594": 6, "reaction_10089574": 4, "species_10089570": 6, "F1N093": 3, "ENSBTAT00000016118": 1, "species_10089560": 6, "Q0VC56": 3, "ENSBTAT00000064422": 1, "species_10089572": 12, "reaction_10091049": 3, "species_10042669": 2, "species_10091047": 3, "reaction_10091096": 6, "species_10091084": 3, "species_10042665": 3, "species_10091093": 3, "G5E521": 3, "ENSBTAT00000002648": 1, "reaction_10091089": 6, "species_10091086": 2, "reaction_10091184": 3, "species_10091182": 3, "A0A452DJI7": 5, "reaction_10091017": 2, "species_10042696": 4, "F1N4K5": 4, "species_10091015": 4, "reaction_10091033": 3, "species_10091013": 2, "species_10037662": 2, "species_10091031": 3, "reaction_10091023": 3, "species_10091019": 4, "species_10091021": 5, "reaction_10091029": 3, "species_10091025": 4, "species_10091027": 5, "reaction_10088872": 5, "species_10088870": 3, "reaction_10088876": 3, "species_10078664": 3, "species_10088874": 3, "reaction_10088887": 2, "species_10088880": 2, "reaction_10086458": 4, "species_10086449": 16, "F1N6T0": 11, "ENSBTAT00000047968": 1, "E1BI59": 11, "ENSBTAT00000004135": 1, "species_10086455": 16, "reaction_10086493": 4, "species_10086477": 9, "species_10086490": 9, "reaction_10086509": 4, "species_10086504": 16, "species_10086506": 16, "reaction_10086525": 4, "species_10086520": 9, "species_10086522": 9, "reaction_10086541": 4, "species_10086536": 9, "species_10086538": 9, "reaction_10086502": 4, "species_10086497": 9, "species_10086499": 9, "reaction_10086518": 4, "species_10086513": 16, "species_10086515": 16, "reaction_10086534": 4, "species_10086529": 16, "species_10086531": 16, "reaction_10086638": 3, "species_10086634": 2, "ENSBTAT00000005068": 2, "species_10063945": 2, "species_10086636": 3, "E1BIP8": 2, "reaction_10084922": 3, "species_10084918": 2, "A0A3Q1M7U2": 7, "ENSBTAT00000072276": 1, "species_10084916": 2, "ENSBTAT00000002913": 2, "species_10084920": 3, "Q32LE1": 2, "reaction_10084911": 3, "species_10084905": 3, "ENSBTAT00000002671": 3, "species_10066845": 2, "species_10084907": 4, "Q0VC14": 8, "reaction_10084895": 5, "species_10084879": 5, "species_10084891": 3, "Q2HJ78": 3, "ENSBTAT00000020109": 1, "Q0VCT9": 3, "ENSBTAT00000014907": 1, "species_10084893": 7, "reaction_10084881": 2, "species_10084877": 3, "reaction_10084935": 4, "species_10069764": 2, "species_10077310": 2, "species_10066847": 2, "species_10084933": 4, "reaction_10084909": 3, "reaction_10084903": 3, "species_10084899": 2, "ENSBTAT00000068462": 2, "species_10084901": 4, "A0A3Q1MKM9": 2, "reaction_10063400": 3, "species_10063396": 3, "species_10063398": 4, "reaction_10063390": 3, "species_10063386": 2, "species_10063388": 3, "reaction_10085761": 3, "species_10063394": 2, "species_10085759": 3, "reaction_10046681": 3, "species_10045690": 35, "A0A3Q1MM20": 3, "ENSBTAT00000072859": 1, "A0A3Q1M5G9": 3, "ENSBTAT00000069224": 1, "F1MXG9": 3, "ENSBTAT00000052227": 1, "A0A3Q1M9Y9": 3, "ENSBTAT00000073553": 1, "F1ML62": 3, "ENSBTAT00000018926": 1, "A0A3Q1LKK0": 3, "ENSBTAT00000068928": 1, "A0A3Q1N5N2": 3, "ENSBTAT00000070997": 1, "Q7YRQ5": 3, "ENSBTAT00000016078": 1, "F1MGG2": 3, "ENSBTAT00000010892": 1, "A0A3S5ZPB3": 3, "ENSBTAT00000012145": 1, "Q04752": 3, "ENSBTAT00000011869": 1, "A0A3Q1LZI4": 3, "ENSBTAT00000074991": 1, "G5E5I7": 3, "ENSBTAT00000020641": 1, "Q08E53": 3, "ENSBTAT00000004758": 1, "A0A3Q1N8R7": 3, "ENSBTAT00000067712": 1, "Q08DY5": 3, "ENSBTAT00000024159": 1, "G3X7C1": 3, "ENSBTAT00000087040": 1, "F1N3S3": 3, "ENSBTAT00000014791": 1, "F1MBX3": 3, "ENSBTAT00000036417": 1, "F1N712": 3, "ENSBTAT00000010545": 1, "A0A3Q1M3W3": 3, "ENSBTAT00000068282": 1, "F1MWI2": 3, "ENSBTAT00000023994": 1, "Q0VC20": 3, "ENSBTAT00000022350": 1, "F1MN19": 3, "ENSBTAT00000077017": 1, "A0A3Q1LZU3": 3, "ENSBTAT00000077868": 1, "O18971": 3, "ENSBTAT00000083374": 1, "A2VDU4": 3, "ENSBTAT00000026059": 1, "E1BML7": 3, "ENSBTAT00000019772": 1, "F1MN68": 3, "ENSBTAT00000018594": 1, "species_10046679": 37, "reaction_10054279": 3, "species_10053367": 2, "ENSBTAT00000008424": 2, "species_10054275": 2, "Q17R08": 3, "ENSBTAT00000080509": 1, "species_10054277": 3, "E1BJG5": 2, "reaction_10065292": 3, "species_10065286": 2, "E1BBP4": 3, "ENSBTAT00000046062": 1, "species_10065288": 8, "species_10065290": 9, "reaction_10068042": 4, "species_10068038": 9, "reaction_10068046": 3, "species_10068044": 6, "reaction_10067891": 3, "species_10037981": 5, "E1BE56": 4, "ENSBTAT00000025281": 1, "species_10067889": 5, "reaction_10037985": 4, "species_10037983": 4, "reaction_10035396": 4, "species_10035390": 5, "reaction_10037991": 4, "species_10037987": 6, "species_10037989": 6, "reaction_10043049": 4, "species_10043047": 2, "species_10043045": 2, "reaction_10044762": 4, "species_10043014": 4, "species_10044758": 2, "species_10044760": 2, "reaction_10043021": 4, "species_10043018": 2, "species_10043016": 2, "reaction_10043059": 4, "species_10043053": 2, "ENSBTAT00000028855": 3, "species_10043057": 2, "species_10043055": 2, "reaction_10044756": 4, "species_10044743": 2, "species_10044745": 2, "reaction_10044923": 4, "species_10040063": 2, "species_10044912": 2, "species_10044910": 2, "species_10044920": 3, "reaction_10044906": 4, "species_10044900": 2, "ENSBTAT00000075747": 4, "species_10044902": 3, "species_10044904": 2, "reaction_10090573": 2, "reaction_10043039": 4, "species_10043037": 2, "species_10043035": 2, "reaction_10044896": 5, "species_10044887": 2, "species_10044893": 2, "species_10044891": 2, "species_10044889": 2, "species_10044867": 3, "reaction_10044995": 4, "species_10044989": 2, "ENSBTAT00000028199": 3, "species_10044993": 2, "species_10044991": 2, "reaction_10044927": 2, "species_10044925": 2, "reaction_10044869": 2, "reaction_10037723": 6, "species_10037716": 3, "A0A3Q1NJ55": 6, "species_10037718": 2, "species_10037721": 3, "reaction_10037727": 2, "species_10037725": 2, "reaction_10037706": 2, "species_10037695": 3, "ENSBTAT00000077917": 3, "species_10037704": 2, "reaction_10037702": 6, "species_10037690": 3, "Q3MHR3": 3, "ENSBTAT00000006190": 1, "Q05KI3": 4, "species_10037692": 2, "reaction_10051181": 3, "species_10037273": 3, "species_10051177": 3, "species_10051179": 4, "reaction_10037277": 3, "reaction_10051175": 3, "species_10051171": 2, "ENSBTAT00000076163": 2, "species_10051167": 5, "A0A3Q1NFP6": 3, "species_10051173": 6, "Q05KJ0": 2, "reaction_10037289": 3, "species_10037283": 4, "reaction_10091191": 3, "species_10037281": 4, "reaction_10091197": 3, "species_10091193": 2, "A0A3Q1MXU1": 3, "species_10091195": 3, "reaction_10091188": 4, "reaction_10039930": 5, "species_175973": 1, "species_175979": 1, "reaction_10038238": 6, "species_158619": 1, "species_158611": 1, "species_10038235": 2, "ENSBTAT00000025698": 1, "reaction_10076898": 5, "species_5696224": 2, "species_5696211": 1, "species_10076895": 3, "ENSBTAT00000069974": 1, "reaction_10071924": 7, "species_10071921": 5, "Q29RI9": 2, "ENSBTAT00000016399": 1, "A0A3Q1MZ37": 2, "ENSBTAT00000075325": 1, "reaction_10076900": 5, "species_5696216": 1, "species_5696214": 2, "reaction_10035863": 9, "species_76384": 1, "species_33153": 1, "reaction_10076903": 6, "species_10039980": 2, "E1BJ08": 3, "ENSBTAT00000017435": 1, "reaction_10037800": 5, "species_10037763": 3, "species_10037765": 3, "species_10037795": 6, "species_10037798": 5, "reaction_10037852": 5, "species_10037785": 4, "species_10037850": 4, "reaction_10037948": 2, "species_10037921": 5, "species_10037945": 5, "reaction_10037950": 3, "species_9693058": 2, "reaction_10037923": 3, "species_10037919": 3, "reaction_10071906": 3, "species_10037841": 3, "species_10037835": 3, "reaction_10090181": 3, "species_9038743": 2, "reaction_10037845": 6, "species_10037817": 2, "species_10037813": 4, "species_10037819": 2, "reaction_10037815": 3, "reaction_10090183": 3, "reaction_10037927": 3, "species_10037925": 2, "reaction_10055529": 3, "species_29868": 2, "species_10055525": 4, "E1BE93": 3, "ENSBTAT00000025252": 2, "species_10055527": 4, "reaction_10055995": 3, "species_10055991": 5, "A7YY73": 3, "ENSBTAT00000028574": 1, "A5PJV0": 3, "ENSBTAT00000000044": 1, "Q5EAD3": 3, "ENSBTAT00000066479": 1, "species_1008228": 1, "species_10055993": 5, "reaction_10055933": 3, "species_10055926": 3, "species_10055929": 2, "species_10055931": 4, "reaction_10055870": 3, "species_10055855": 2, "ENSBTAT00000008198": 2, "species_10055866": 4, "species_10055868": 5, "F2Z4J7": 2, "reaction_10055649": 3, "species_10055519": 2, "reaction_10055920": 3, "species_10055890": 3, "E1BBZ5": 3, "ENSBTAT00000002161": 1, "species_10055916": 7, "A0A3Q1MC01": 3, "ENSBTAT00000066877": 1, "F1N1M2": 3, "ENSBTAT00000007537": 1, "A0A3Q1MGB0": 3, "ENSBTAT00000071546": 1, "F1N551": 3, "ENSBTAT00000007134": 1, "Q3SZJ5": 3, "ENSBTAT00000027184": 1, "species_10055918": 9, "reaction_10056002": 5, "species_10055999": 2, "ENSBTAT00000022789": 1, "reaction_10055847": 2, "species_10055843": 2, "species_10055845": 2, "reaction_10085753": 3, "species_10085749": 5, "A0A3Q1LX90": 3, "ENSBTAT00000085051": 2, "A0A3Q1M7Z2": 3, "ENSBTAT00000081146": 1, "A0A3Q1MS45": 3, "species_10085701": 4, "species_10085751": 8, "reaction_10043323": 2, "species_10043319": 3, "ENSBTAT00000080737": 2, "species_10043321": 2, "A4IFI9": 3, "reaction_10043355": 2, "species_10043351": 2, "species_10043353": 2, "reaction_10043375": 3, "species_10043367": 2, "ENSBTAT00000014924": 2, "species_10043371": 2, "ENSBTAT00000084280": 2, "species_10043373": 3, "A0A3Q1LFU5": 2, "Q2KHZ6": 2, "reaction_10044024": 3, "species_10044022": 3, "reaction_10044030": 2, "species_10044028": 3, "reaction_10044034": 3, "species_10044032": 3, "reaction_10044039": 5, "species_10044036": 2, "reaction_10043393": 3, "species_10043379": 2, "ENSBTAT00000029578": 2, "species_10043389": 3, "P98107": 4, "ENSBTAT00000009612": 2, "Q2KJA9": 3, "ENSBTAT00000057091": 1, "species_10043391": 4, "F1MS77": 4, "reaction_10043363": 3, "species_10043359": 3, "ENSBTAT00000081263": 2, "species_10043361": 3, "A0A3Q1M4F2": 3, "reaction_10043347": 3, "species_10043343": 2, "species_10043339": 2, "ENSBTAT00000022936": 2, "species_10043345": 3, "Q148M9": 2, "reaction_10043397": 2, "species_10043395": 2, "reaction_10043335": 2, "species_10043331": 2, "ENSBTAT00000053223": 2, "species_10043333": 2, "F1N7U9": 2, "reaction_10066263": 3, "species_10066259": 4, "A0A3Q1LL67": 3, "ENSBTAT00000083484": 1, "A6QQP5": 3, "ENSBTAT00000037368": 1, "species_10043387": 2, "species_10066261": 5, "reaction_10038329": 3, "species_10038260": 5, "species_10038324": 2, "species_10038326": 3, "reaction_10038285": 4, "species_10038272": 4, "species_10038267": 6, "species_10038283": 3, "P60902": 2, "ENSBTAT00000020150": 1, "reaction_10038303": 4, "species_10038296": 3, "species_10038298": 3, "species_10038300": 3, "reaction_10038270": 3, "species_10038248": 5, "reaction_10038288": 3, "species_10038252": 3, "species_10038254": 4, "reaction_10038307": 4, "species_10038305": 3, "reaction_10038290": 3, "species_157771": 1, "species_10038265": 2, "reaction_10038292": 3, "reaction_10038263": 3, "reaction_10057598": 3, "species_10057594": 3, "ENSBTAT00000013434": 4, "species_10057592": 3, "species_10057596": 2, "G5E5C6": 2, "reaction_10057605": 3, "species_10057602": 2, "reaction_10091211": 3, "species_10091207": 8, "species_10091201": 2, "ENSBTAT00000084434": 2, "species_10091209": 10, "A0A3Q1M1H9": 6, "reaction_10091566": 2, "species_10091562": 2, "species_10091564": 2, "reaction_10035854": 3, "species_76050": 1, "species_10035850": 2, "ENSBTAT00000016732": 2, "species_10035852": 2, "F1MUY9": 2, "reaction_10036760": 3, "species_10036755": 2, "species_110242": 1, "reaction_10091240": 3, "species_10091237": 2, "species_9629439": 1, "species_10091230": 3, "reaction_10036782": 3, "species_10036777": 2, "F1N4K4": 3, "ENSBTAT00000014928": 1, "species_10036779": 2, "reaction_10036798": 3, "species_10036795": 2, "F1MKN2": 5, "ENSBTAT00000037548": 1, "species_10036788": 4, "species_110249": 1, "reaction_10091233": 3, "species_10091226": 2, "species_9629218": 2, "reaction_10036805": 3, "species_10036802": 2, "reaction_10036791": 3, "species_10036786": 2, "species_30947": 1, "reaction_10091222": 3, "species_10091219": 9, "reaction_10072876": 3, "species_10072868": 3, "ENSBTAT00000000131": 2, "species_10072872": 9, "A0A3Q1N5S1": 14, "ENSBTAT00000076791": 1, "species_10072874": 11, "E1BKF4": 2, "reaction_10072883": 5, "species_10072880": 2, "species_10072878": 8, "reaction_10073302": 3, "species_10073294": 2, "ENSBTAT00000054209": 2, "species_10073300": 5, "Q5E9B2": 2, "reaction_10044547": 5, "species_171149": 1, "species_194276": 1, "species_194236": 1, "species_171076": 1, "species_10044544": 2, "ENSBTAT00000024018": 1, "reaction_10088982": 5, "species_174602": 4, "species_10088979": 2, "A0A3Q1LR40": 2, "ENSBTAT00000075023": 1, "reaction_10084509": 3, "species_10077472": 3, "ENSBTAT00000071232": 2, "species_10077480": 4, "species_1678620": 4, "P11151": 4, "ENSBTAT00000017086": 2, "species_10077482": 5, "A0A3Q1MPP4": 2, "reaction_10077487": 5, "species_10077476": 2, "species_10077484": 2, "reaction_10077489": 3, "species_10077478": 2, "reaction_10077593": 3, "species_10077506": 2, "ENSBTAT00000071085": 2, "species_10077502": 2, "ENSBTAT00000065656": 2, "species_10077508": 3, "Q2KHY5": 5, "A0A3Q1MT39": 5, "reaction_10077625": 6, "species_10077619": 2, "E1BN11": 3, "ENSBTAT00000026896": 1, "species_10077582": 16, "E1BE83": 4, "ENSBTAT00000013299": 1, "A0A452DIP1": 4, "ENSBTAT00000018787": 1, "F1MWV7": 4, "ENSBTAT00000009509": 1, "E1B6X8": 4, "ENSBTAT00000002478": 1, "A6QQ29": 4, "ENSBTAT00000056722": 1, "G3X787": 4, "ENSBTAT00000082853": 1, "Q2TBN8": 4, "ENSBTAT00000007713": 1, "species_10077609": 2, "ENSBTAT00000085708": 2, "species_10077623": 23, "A0A3Q1MJE2": 2, "reaction_10077591": 4, "species_10077569": 13, "A0A3Q1MQ26": 3, "ENSBTAT00000068467": 1, "species_10077588": 5, "reaction_10035372": 5, "species_73917": 1, "species_10035369": 2, "ENSBTAT00000005088": 1, "reaction_10035363": 11, "reaction_10049883": 3, "species_10049879": 3, "ENSBTAT00000081787": 2, "species_10049875": 2, "species_10049881": 3, "A0A3Q1LMM6": 3, "reaction_10049312": 3, "species_10049308": 2, "ENSBTAT00000084501": 2, "species_10049310": 3, "A0A3Q1M7B6": 2, "reaction_10049891": 3, "species_10049887": 2, "ENSBTAT00000082961": 2, "species_10049889": 3, "A0A3Q1MET9": 2, "reaction_10038942": 1, "species_10035753": 2, "reaction_10036844": 3, "species_10036840": 11, "species_10036809": 2, "ENSBTAT00000066497": 2, "species_10036842": 13, "A0A3Q1MPW7": 3, "reaction_10036853": 3, "species_10036850": 12, "reaction_10073275": 5, "species_10073270": 15, "F1MZ79": 8, "ENSBTAT00000007900": 2, "A5D979": 4, "ENSBTAT00000008030": 2, "F1N7U2": 3, "ENSBTAT00000042613": 1, "species_10073272": 14, "species_10036857": 4, "reaction_10073290": 4, "species_10073277": 4, "A4IFE2": 2, "ENSBTAT00000009461": 2, "species_10073287": 5, "species_10036867": 4, "reaction_10036879": 4, "species_10036863": 13, "species_10036876": 13, "reaction_10073279": 3, "reaction_10036869": 4, "species_10036861": 11, "reaction_10036886": 4, "species_10036883": 13, "reaction_10073254": 3, "species_10073250": 2, "species_10073252": 13, "reaction_10090392": 4, "reaction_10090394": 4, "reaction_10090462": 5, "species_9024873": 1, "reaction_10090384": 4, "reaction_10090464": 5, "reaction_10090458": 5, "species_9024764": 1, "species_9024799": 3, "CHEBI:132797": 1, "CHEBI:132800": 1, "species_10064497": 4, "Q309F3": 2, "ENSBTAT00000027024": 1, "reaction_10090390": 6, "species_9024815": 1, "species_10090371": 5, "reaction_10090388": 6, "species_9024463": 1, "reaction_10062377": 4, "species_10062335": 7, "species_10058697": 7, "species_10062368": 3, "species_10062375": 3, "Q2HJB6": 2, "ENSBTAT00000027347": 1, "F1MKP1": 2, "ENSBTAT00000021330": 1, "reaction_10061787": 6, "species_10061734": 4, "CHEBI:29073": 2, "A6QLY3": 3, "ENSBTAT00000027999": 1, "species_1650779": 1, "species_1650769": 1, "species_10061784": 4, "reaction_10060187": 2, "species_10060185": 5, "reaction_10087626": 3, "species_10061921": 1, "species_10061791": 3, "ENSBTAT00000050322": 2, "species_10061923": 3, "F1N0V8": 3, "reaction_10062058": 4, "species_1981137": 1, "species_10062055": 3, "reaction_10087628": 3, "species_10062053": 1, "reaction_10060191": 2, "species_10060189": 4, "reaction_10064337": 2, "species_10062852": 4, "species_10064335": 4, "reaction_10062352": 3, "species_10062205": 6, "species_10062349": 4, "E1BC50": 2, "ENSBTAT00000061447": 1, "E1BFV4": 2, "ENSBTAT00000028224": 1, "reaction_10063799": 3, "species_10063637": 21, "Q2KJH6": 2, "ENSBTAT00000083385": 2, "species_10063797": 17, "species_10062846": 2, "reaction_10064491": 4, "species_9032038": 1, "species_2161856": 3, "CHEBI:6499": 1, "species_2161759": 2, "reaction_10064500": 6, "species_2142761": 1, "reaction_10065691": 3, "species_10062553": 2, "species_10065689": 5, "reaction_10065300": 3, "species_10065296": 5, "species_10065298": 6, "reaction_10064953": 2, "species_10058703": 7, "species_10064951": 6, "reaction_10064959": 2, "species_10064955": 6, "species_10064957": 9, "reaction_10058705": 2, "reaction_10065929": 4, "species_10065920": 3, "species_10065926": 3, "CHEBI:15858": 1, "A0A3Q1LMN6": 2, "ENSBTAT00000073028": 1, "reaction_10035464": 5, "species_30064": 1, "species_10035461": 3, "F1MLX9": 2, "ENSBTAT00000015339": 1, "reaction_10088571": 5, "species_109327": 5, "species_8953344": 1, "species_10088568": 2, "ENSBTAT00000026530": 1, "reaction_10035453": 9, "species_500172": 4, "CHEBI:28997": 4, "species_113599": 2, "species_500244": 10, "CHEBI:28542": 1, "species_10035450": 3, "reaction_10036207": 5, "species_500101": 5, "species_500104": 5, "reaction_10035455": 9, "species_500245": 4, "CHEBI:17172": 5, "reaction_10036238": 6, "species_10036235": 2, "ENSBTAT00000006950": 1, "reaction_10036256": 5, "species_500120": 5, "species_500118": 5, "species_10036253": 4, "G3X6X2": 2, "ENSBTAT00000015317": 1, "reaction_10036231": 6, "species_500125": 7, "species_500124": 7, "species_10036226": 4, "E1BF39": 2, "ENSBTAT00000003884": 1, "reaction_10053044": 4, "species_10053039": 100, "Q0VC92": 3, "ENSBTAT00000025615": 1, "A0A452DHY5": 3, "ENSBTAT00000004528": 1, "A0A3Q1LRF2": 3, "ENSBTAT00000075557": 1, "A6QR16": 3, "ENSBTAT00000078713": 1, "F1MBL6": 3, "ENSBTAT00000027632": 1, "species_10053041": 100, "reaction_10090377": 4, "species_9022921": 3, "species_9023653": 2, "species_9020583": 2, "reaction_10090440": 5, "species_9023963": 1, "reaction_10090396": 4, "species_9020474": 2, "species_9022679": 1, "reaction_10090374": 6, "reaction_10090379": 6, "species_9023651": 2, "reaction_10090382": 4, "species_9023644": 1, "reaction_10065866": 3, "species_10065861": 10, "E1B9V5": 3, "ENSBTAT00000024903": 1, "A0A452DHU9": 3, "ENSBTAT00000002352": 1, "F1MED0": 3, "ENSBTAT00000056871": 1, "E1BGU6": 3, "ENSBTAT00000045580": 1, "F1N390": 3, "ENSBTAT00000019622": 1, "G3MZP0": 3, "ENSBTAT00000063395": 1, "F1N4E7": 3, "ENSBTAT00000019586": 1, "reaction_10065884": 3, "species_1132304": 1, "species_10065881": 2, "reaction_10065886": 3, "species_10065863": 8, "species_1449667": 1, "reaction_10065875": 3, "species_10065872": 2, "A0A3S5ZP59": 2, "ENSBTAT00000038859": 1, "reaction_10076856": 8, "species_5696128": 1, "species_10076853": 4, "reaction_10077496": 5, "species_6784964": 1, "species_10077493": 2, "ENSBTAT00000008368": 1, "reaction_10076475": 4, "species_5694080": 1, "species_5694091": 1, "species_10076472": 2, "ENSBTAT00000083641": 1, "reaction_10076863": 8, "species_5696181": 1, "species_5696178": 1, "species_10076860": 2, "ENSBTAT00000042833": 1, "reaction_10076884": 8, "species_5696148": 1, "species_5696154": 1, "species_10076881": 6, "Q9TTK6": 2, "ENSBTAT00000081083": 2, "A0A452DHX8": 2, "ENSBTAT00000001383": 1, "Q29437": 2, "reaction_10076375": 6, "species_5693702": 1, "species_5693711": 1, "species_5693712": 1, "species_10076372": 3, "F1MU22": 2, "ENSBTAT00000032343": 1, "reaction_10086550": 5, "species_8937424": 1, "species_8937418": 1, "species_10086547": 2, "ENSBTAT00000024873": 1, "reaction_10044524": 8, "species_217269": 1, "species_10044521": 3, "A0A3Q1M207": 2, "ENSBTAT00000079411": 1, "reaction_10044533": 8, "species_217315": 1, "species_217320": 1, "species_10044530": 4, "G5E540": 2, "ENSBTAT00000003873": 1, "reaction_10034175": 7, "reaction_10034206": 6, "species_30203": 1, "species_10034203": 6, "E1BBW9": 2, "ENSBTAT00000020879": 1, "F1MZN9": 2, "ENSBTAT00000009191": 1, "reaction_10050160": 7, "species_113539": 2, "species_10050157": 2, "ENSBTAT00000086374": 1, "reaction_10076144": 6, "species_5692221": 1, "species_5692249": 1, "species_10076141": 3, "Q3ZC42": 2, "ENSBTAT00000021304": 1, "reaction_10034215": 7, "reaction_10034231": 7, "species_10034228": 2, "ENSBTAT00000078990": 2, "reaction_10075404": 5, "species_5689006": 1, "species_5689001": 1, "species_5688995": 1, "species_10075401": 2, "ENSBTAT00000015373": 1, "reaction_10086543": 3, "species_10035973": 2, "species_10035969": 3, "reaction_10086469": 7, "species_8936516": 1, "species_8936520": 1, "species_8936514": 1, "species_8936507": 1, "species_10086466": 3, "Q3SZT2": 2, "ENSBTAT00000072063": 1, "species_209934": 1, "species_1130942": 1, "reaction_10077734": 5, "species_6786175": 1, "species_6786194": 1, "species_6786179": 1, "species_10077731": 2, "ENSBTAT00000072469": 1, "reaction_10041241": 5, "reaction_10088973": 5, "species_10088970": 1, "reaction_10041239": 5, "reaction_10076274": 5, "species_5693375": 1, "species_5693410": 1, "species_10076271": 3, "P56965": 2, "ENSBTAT00000049235": 1, "Q3SX44": 2, "ENSBTAT00000085909": 1, "reaction_10040617": 5, "species_188973": 1, "species_10040614": 2, "E1BK89": 2, "ENSBTAT00000020185": 1, "reaction_10040872": 5, "species_191103": 5, "species_188986": 7, "species_10040626": 3, "reaction_10040620": 5, "species_189049": 1, "species_10040605": 6, "E1BGH5": 2, "ENSBTAT00000023366": 1, "reaction_10040608": 6, "species_189108": 2, "reaction_10040595": 5, "species_189075": 2, "species_10040592": 5, "F1MJQ3": 2, "ENSBTAT00000082976": 1, "F1MP21": 2, "ENSBTAT00000060970": 1, "A0A3Q1LQY4": 2, "ENSBTAT00000083621": 1, "reaction_10040866": 5, "reaction_10073378": 4, "species_5659875": 1, "reaction_10040629": 4, "reaction_10040868": 4, "reaction_10040870": 6, "species_189071": 2, "reaction_10086435": 3, "species_10086431": 2, "F1N5B2": 3, "ENSBTAT00000026286": 1, "species_10086425": 3, "E1BIM0": 3, "ENSBTAT00000009466": 1, "E1BIM1": 3, "ENSBTAT00000009465": 1, "species_10086433": 4, "reaction_10036917": 3, "reaction_10039865": 7, "species_174393": 2, "species_10039862": 3, "A0A3Q1MN33": 2, "ENSBTAT00000081594": 1, "Q2T9Y6": 2, "ENSBTAT00000026855": 1, "reaction_10087515": 5, "species_1247934": 1, "species_10071751": 3, "reaction_10077658": 4, "species_1247942": 2, "species_1247904": 1, "species_10077655": 3, "A6H738": 2, "ENSBTAT00000013689": 1, "Q0IIH4": 2, "ENSBTAT00000025922": 1, "reaction_10057079": 4, "species_10057076": 2, "Q32LE4": 2, "ENSBTAT00000014010": 1, "reaction_10075362": 6, "species_5688282": 1, "species_10075353": 2, "species_5688281": 1, "species_5688340": 1, "species_10075359": 3, "Q3ZBQ0": 2, "ENSBTAT00000072664": 1, "reaction_10075350": 6, "species_10075337": 4, "A0A3Q1MB37": 3, "species_5688337": 1, "species_5688274": 1, "species_10075341": 4, "species_10075347": 3, "reaction_10072271": 3, "species_10072269": 3, "Q58CS6": 2, "ENSBTAT00000084852": 2, "species_10072263": 2, "species_10072267": 2, "reaction_10058751": 5, "species_10058748": 7, "A0A3Q1MAE5": 2, "ENSBTAT00000071702": 1, "Q3SZX4": 2, "ENSBTAT00000020243": 1, "reaction_10058753": 5, "species_10058719": 5, "A0A3Q1MI50": 2, "ENSBTAT00000067395": 1, "E1BPA4": 2, "ENSBTAT00000015174": 1, "reaction_10058755": 5, "reaction_10058722": 5, "reaction_10058772": 5, "species_10058769": 5, "A0A3Q1LWK4": 2, "ENSBTAT00000068215": 1, "F1N5D1": 2, "ENSBTAT00000027210": 1, "reaction_10058774": 5, "reaction_10040030": 4, "species_158543": 1, "species_176065": 4, "species_159211": 3, "CHEBI:29132": 2, "species_176048": 4, "CHEBI:32639": 2, "CHEBI:2505": 1, "CHEBI:35896": 1, "species_10040027": 3, "Q2KJG4": 2, "ENSBTAT00000029028": 1, "reaction_10067425": 5, "species_3301954": 2, "species_3301969": 2, "species_10067422": 2, "F1MRG0": 2, "ENSBTAT00000012969": 1, "reaction_10040021": 4, "species_176070": 4, "CHEBI:30614": 1, "species_176049": 4, "CHEBI:34479": 1, "species_10040018": 14, "E1BKD8": 4, "ENSBTAT00000035828": 2, "F1MX44": 4, "O18879": 4, "ENSBTAT00000046354": 1, "Q2NL00": 2, "ENSBTAT00000007403": 1, "A1A4L7": 2, "ENSBTAT00000021896": 1, "A0A3Q1LSN6": 2, "ENSBTAT00000085178": 1, "reaction_10076133": 5, "species_5692212": 1, "species_5692216": 1, "reaction_10040185": 7, "species_177153": 1, "species_177137": 1, "reaction_10038316": 4, "species_10038311": 5, "ENSBTAT00000048506": 2, "species_10038314": 5, "reaction_10039918": 4, "reaction_10039921": 4, "species_174969": 5, "CHEBI:45373": 1, "CHEBI:30753": 1, "CHEBI:27565": 1, "species_174960": 5, "CHEBI:63845": 1, "CHEBI:16395": 2, "CHEBI:63815": 1, "CHEBI:63817": 1, "reaction_10039923": 4, "species_174971": 4, "CHEBI:6030": 1, "species_174958": 4, "CHEBI:7207": 1, "CHEBI:32643": 1, "reaction_10071722": 8, "species_5423605": 4, "species_5423660": 1, "species_10071719": 5, "reaction_10071754": 5, "species_5490253": 3, "CHEBI:78581": 2, "CHEBI:78587": 2, "species_5490235": 3, "CHEBI:78579": 1, "CHEBI:78584": 1, "reaction_10038060": 8, "species_10038057": 7, "reaction_10071727": 8, "species_5423663": 2, "species_10071724": 3, "reaction_10071729": 8, "species_5423629": 2, "reaction_10071712": 6, "species_5423727": 1, "species_5423729": 1, "species_10071709": 3, "F1MZC0": 2, "ENSBTAT00000016300": 1, "F1N6I4": 2, "ENSBTAT00000038217": 1, "reaction_10071715": 8, "species_5423657": 1, "species_10035869": 2, "reaction_10071763": 5, "species_5490236": 3, "CHEBI:78580": 1, "CHEBI:78585": 1, "species_5490231": 3, "CHEBI:78583": 1, "CHEBI:78578": 1, "species_10071760": 3, "F1MR63": 2, "ENSBTAT00000024787": 1, "reaction_10071717": 4, "species_5423723": 3, "species_5423730": 3, "reaction_10074761": 3, "species_10074753": 2, "species_10074751": 2, "ENSBTAT00000016216": 3, "species_10074755": 4, "Q3SYV6": 2, "reaction_10035720": 3, "species_10035716": 3, "species_10035710": 4, "reaction_10035712": 3, "species_10035708": 2, "species_10035704": 2, "reaction_10074759": 3, "species_10074757": 2, "reaction_10074747": 4, "species_10074743": 2, "ENSBTAT00000069360": 2, "species_10074733": 12, "species_10074745": 11, "A0A3Q1MU04": 2, "reaction_10074558": 4, "species_10074548": 15, "E1B782": 3, "ENSBTAT00000018496": 2, "E1BI26": 11, "ENSBTAT00000035900": 1, "A4FV15": 3, "ENSBTAT00000001000": 2, "species_10074555": 14, "reaction_10074736": 5, "species_10074724": 2, "ENSBTAT00000074020": 2, "species_10074727": 3, "reaction_10074739": 5, "species_10074663": 10, "reaction_10074677": 4, "species_10074674": 10, "species_10074667": 11, "reaction_10074679": 3, "species_10074542": 11, "species_10074544": 11, "reaction_10074550": 4, "species_10069303": 2, "species_10074546": 12, "species_10069553": 2, "reaction_10076329": 3, "species_10076288": 2, "species_10076290": 11, "reaction_10076332": 4, "species_10074530": 7, "reaction_10076303": 4, "species_10076300": 10, "reaction_10076334": 3, "species_10074715": 5, "reaction_10074670": 4, "reaction_10074720": 5, "species_10074711": 4, "species_10074717": 3, "reaction_10076293": 4, "species_10074665": 10, "reaction_10075173": 5, "species_10075167": 2, "reaction_10049230": 5, "species_429926": 1, "species_430042": 1, "species_429925": 1, "species_10049227": 2, "ENSBTAT00000003732": 1, "reaction_10049232": 3, "species_10049219": 7, "A6QQV3": 3, "ENSBTAT00000007405": 1, "A0A452DIA6": 3, "ENSBTAT00000009684": 1, "F1N6T3": 3, "ENSBTAT00000005939": 1, "A0A3Q1M2U2": 3, "ENSBTAT00000069947": 1, "A0A3Q1LMH1": 3, "ENSBTAT00000072254": 1, "A0A3Q1LRX5": 3, "ENSBTAT00000077566": 1, "species_429974": 1, "species_10049221": 7, "reaction_10061043": 5, "species_2024002": 1, "species_2024016": 1, "species_10060960": 4, "ENSBTAT00000007784": 1, "reaction_10060963": 5, "species_2024008": 1, "species_2024012": 1, "reaction_10061122": 5, "species_2024018": 1, "species_2564836": 1, "reaction_10036907": 5, "species_10035351": 6, "CHEBI:17909": 2, "F1MV22": 3, "ENSBTAT00000052667": 1, "species_10036905": 5, "species_29602": 5, "reaction_10035339": 6, "species_111369": 1, "species_111370": 2, "species_10035336": 4, "ENSBTAT00000012108": 1, "reaction_10035354": 13, "species_111292": 3, "reaction_10036909": 3, "reaction_10035308": 9, "species_111584": 3, "species_10035305": 2, "ENSBTAT00000084984": 1, "reaction_10091727": 3, "species_9678719": 1, "species_10035314": 3, "species_10035317": 3, "reaction_10035342": 5, "species_111338": 2, "species_419151": 1, "species_111354": 1, "reaction_10035345": 7, "reaction_10035329": 7, "species_111395": 2, "species_111399": 1, "species_10035326": 3, "F1MN04": 2, "ENSBTAT00000013985": 1, "reaction_10036928": 11, "species_35141": 2, "species_10036925": 3, "A7MBG0": 2, "ENSBTAT00000047061": 1, "reaction_10035332": 4, "reaction_10035319": 9, "reaction_10076312": 4, "species_10076309": 5, "E1BLB6": 7, "ENSBTAT00000022631": 2, "species_10075286": 4, "reaction_10076347": 3, "species_10076305": 2, "species_10076345": 3, "reaction_10075295": 4, "species_10075288": 4, "species_10075292": 5, "reaction_10076286": 2, "species_10076283": 5, "reaction_10076327": 3, "species_10076314": 4, "species_10076324": 1, "reaction_10036649": 5, "species_500759": 5, "species_500761": 5, "species_10036646": 2, "A0A3Q1LZ00": 2, "ENSBTAT00000077740": 1, "reaction_10034989": 5, "species_10034986": 2, "A0A452DII0": 2, "ENSBTAT00000014316": 1, "reaction_10035020": 5, "species_10035017": 2, "A0A3Q1NEX0": 2, "ENSBTAT00000073714": 1, "reaction_10035007": 5, "species_500829": 4, "CHEBI:15698": 3, "species_500430": 7, "CHEBI:16450": 5, "species_10035004": 3, "reaction_10088624": 5, "species_10088621": 2, "ENSBTAT00000071389": 1, "reaction_10034980": 5, "species_500828": 3, "species_109378": 7, "species_10034977": 4, "Q3MHR2": 2, "ENSBTAT00000016449": 1, "reaction_10035479": 9, "species_83962": 4, "species_10035476": 4, "F1N0Y0": 2, "ENSBTAT00000011088": 1, "A0A3Q1MGK3": 2, "ENSBTAT00000082335": 1, "reaction_10036614": 5, "species_500822": 4, "species_500823": 4, "species_500742": 6, "species_10036611": 2, "ENSBTAT00000064369": 1, "reaction_10069313": 3, "species_10069309": 6, "A0A3Q1N3A0": 5, "ENSBTAT00000073403": 1, "F1N0T1": 5, "ENSBTAT00000023245": 1, "species_10069311": 7, "reaction_10044515": 3, "species_10044511": 1, "species_10044513": 3, "reaction_10065555": 3, "species_10065551": 9, "A0A3Q1N9E9": 3, "ENSBTAT00000069112": 1, "F1MDD5": 3, "ENSBTAT00000060991": 1, "A6QNS6": 3, "ENSBTAT00000009531": 1, "species_10065553": 12, "reaction_10047065": 7, "species_8848577": 2, "species_10047062": 2, "ENSBTAT00000014725": 1, "reaction_10083577": 5, "species_30209": 2, "species_2534407": 2, "reaction_10083575": 5, "species_8848499": 1, "reaction_10091611": 3, "species_10091609": 7, "species_10091607": 6, "species_189386": 4, "reaction_10091613": 3, "reaction_10091598": 3, "species_9661418": 2, "reaction_10091605": 3, "species_10091602": 2, "reaction_10069412": 3, "species_10069410": 3, "reaction_10074474": 5, "species_10074459": 2, "F1MG24": 4, "ENSBTAT00000027538": 1, "species_10074467": 3, "species_10074471": 2, "ENSBTAT00000006197": 1, "reaction_10074486": 2, "species_10074478": 2, "reaction_10076091": 3, "species_10076089": 3, "reaction_10059181": 5, "species_5691103": 1, "species_10059178": 5, "reaction_10076083": 4, "species_10076005": 2, "ENSBTAT00000077304": 2, "species_10076074": 2, "species_10076080": 4, "reaction_10052866": 4, "species_917828": 1, "species_10052863": 3, "F1MLZ1": 2, "ENSBTAT00000010387": 1, "reaction_10052916": 3, "reaction_10087646": 5, "species_2889072": 1, "species_8949220": 1, "species_8949232": 1, "species_2889083": 1, "species_10087643": 2, "reaction_10061116": 5, "species_1629755": 2, "species_10060953": 6, "reaction_10060956": 5, "species_1629765": 5, "species_1629759": 1, "reaction_10061040": 5, "species_10060977": 8, "A2VDV0": 3, "ENSBTAT00000009797": 1, "A7MBH2": 2, "ENSBTAT00000085197": 1, "reaction_10061011": 5, "species_10061008": 2, "reaction_10060980": 5, "species_2023968": 4, "species_1629732": 3, "CHEBI:62924": 1, "reaction_10060983": 5, "species_2023943": 4, "species_1629736": 2, "CHEBI:62927": 1, "species_10060969": 4, "reaction_10061079": 5, "species_1629740": 3, "species_10061021": 3, "ENSBTAT00000072742": 1, "reaction_10061034": 5, "species_1629738": 1, "reaction_10063018": 5, "species_2023974": 4, "CHEBI:62922": 1, "reaction_10061037": 5, "reaction_10063020": 5, "reaction_10061024": 5, "reaction_10061125": 5, "reaction_10061113": 5, "species_10061110": 7, "E1BJE0": 2, "ENSBTAT00000034821": 1, "F1MTE8": 2, "ENSBTAT00000078103": 1, "A0A3Q1M8P8": 2, "ENSBTAT00000085120": 1, "reaction_10061084": 5, "species_994170": 2, "species_10061081": 4, "reaction_10061006": 5, "species_10061003": 4, "Q1RML2": 2, "ENSBTAT00000017574": 1, "reaction_10060917": 5, "species_10060914": 6, "A0A3Q1LNH2": 2, "ENSBTAT00000070709": 1, "F1MN32": 2, "ENSBTAT00000025930": 1, "A4FV33": 2, "ENSBTAT00000002194": 1, "reaction_10061076": 5, "species_2023856": 1, "species_10061073": 3, "A0A3Q1LJY0": 2, "ENSBTAT00000074483": 1, "reaction_10036003": 3, "species_10034244": 2, "species_10034248": 2, "species_10034250": 3, "reaction_10084424": 3, "species_10084420": 3, "A4FUX1": 3, "ENSBTAT00000083406": 1, "A0A3Q1LUM0": 3, "ENSBTAT00000079299": 1, "species_8866926": 5, "species_10084422": 6, "reaction_10084480": 3, "species_10084476": 3, "A4IFN5": 3, "ENSBTAT00000026679": 1, "A0A452DJ11": 3, "ENSBTAT00000028518": 1, "species_10084478": 4, "reaction_10084694": 3, "species_10084690": 2, "ENSBTAT00000038453": 2, "species_10084692": 5, "Q29RS1": 2, "reaction_10083544": 5, "species_10083541": 3, "ENSBTAT00000021067": 1, "reaction_10083547": 6, "reaction_10071388": 3, "species_10071384": 9, "F1MHQ4": 3, "ENSBTAT00000000079": 1, "Q09139": 3, "ENSBTAT00000017593": 1, "F1MFF7": 3, "ENSBTAT00000022662": 1, "F1MRS8": 3, "ENSBTAT00000000867": 1, "P10790": 3, "ENSBTAT00000022375": 1, "G3N125": 3, "ENSBTAT00000066006": 1, "species_10071386": 10, "reaction_10035435": 5, "species_10035432": 2, "reaction_10051215": 7, "species_10051212": 3, "F1MCZ0": 2, "ENSBTAT00000003519": 1, "F6R1R5": 2, "ENSBTAT00000020904": 1, "reaction_10036001": 5, "species_10035998": 4, "F1MLX6": 2, "ENSBTAT00000015348": 1, "A0A3Q1M723": 2, "ENSBTAT00000080896": 1, "reaction_10035426": 5, "species_500224": 4, "species_500222": 4, "species_10035423": 2, "Q2KIN2": 2, "ENSBTAT00000047239": 1, "reaction_10036306": 5, "species_500173": 3, "species_500088": 3, "species_10036303": 3, "A0A3Q1MB39": 2, "ENSBTAT00000071820": 1, "reaction_10036308": 5, "species_500201": 3, "species_500199": 3, "reaction_10035444": 5, "species_500259": 3, "species_500260": 3, "species_10035441": 3, "Q3SZ18": 2, "ENSBTAT00000019547": 1, "reaction_10050378": 5, "species_10050287": 3, "ENSBTAT00000000805": 4, "species_10050298": 3, "species_10050375": 2, "reaction_10050368": 3, "species_450613": 1, "species_10050289": 2, "Q3ZCE2": 7, "reaction_10050400": 3, "species_10050304": 9, "P51122": 2, "ENSBTAT00000016410": 2, "F1MH31": 2, "ENSBTAT00000029190": 2, "species_10050398": 2, "species_10050382": 2, "reaction_10051219": 3, "species_10050293": 2, "species_450605": 1, "species_10050295": 2, "reaction_10050306": 7, "species_10050261": 2, "species_10050273": 2, "species_10050302": 2, "species_10050269": 2, "reaction_10051221": 3, "species_517622": 1, "species_10050300": 2, "reaction_10051066": 3, "species_10050363": 3, "A7MB98": 6, "ENSBTAT00000084778": 2, "species_10051064": 3, "reaction_10050366": 5, "species_10050357": 3, "reaction_10050318": 3, "species_10050314": 2, "species_10050316": 3, "reaction_10050373": 3, "species_450523": 1, "species_10050355": 2, "reaction_10050408": 3, "species_10050402": 2, "species_10050371": 2, "ENSBTAT00000070369": 3, "species_10050406": 3, "A0A3Q1N6L6": 3, "reaction_10050380": 3, "species_10050322": 2, "species_450386": 1, "species_10050324": 2, "reaction_10049346": 3, "species_400452": 1, "species_10049343": 2, "reaction_10049351": 7, "species_1132084": 1, "species_10049348": 2, "reaction_10044634": 8, "species_10044615": 5, "species_6790050": 3, "species_10044619": 4, "reaction_10047765": 3, "reaction_10034971": 5, "species_109382": 2, "species_10034968": 2, "A6QQC3": 2, "ENSBTAT00000083533": 1, "reaction_10035038": 9, "species_10035035": 2, "A0JNE9": 2, "ENSBTAT00000068403": 1, "reaction_10035698": 9, "species_500006": 5, "CHEBI:28846": 4, "species_500009": 5, "species_10034909": 2, "ENSBTAT00000026582": 1, "reaction_10035029": 9, "species_499997": 4, "species_499999": 4, "CHEBI:28850": 2, "species_10035026": 2, "A0A3Q1N7A8": 2, "ENSBTAT00000069715": 1, "reaction_10036692": 7, "species_10036689": 2, "ENSBTAT00000023406": 1, "reaction_10034998": 5, "species_10034995": 3, "A0A3Q1NID0": 2, "ENSBTAT00000077973": 1, "reaction_10036683": 9, "species_6788782": 7, "CHEBI:16174": 3, "species_6788778": 7, "species_10036680": 5, "A0A3Q1MKM8": 2, "ENSBTAT00000076708": 1, "E1B7Q2": 2, "ENSBTAT00000061550": 1, "F1MUF5": 2, "ENSBTAT00000020294": 1, "reaction_10036938": 4, "species_10036935": 2, "ENSBTAT00000001575": 2, "species_10036932": 2, "reaction_10036685": 5, "reaction_10051075": 9, "species_482803": 10, "CHEBI:28862": 1, "species_482807": 10, "species_500739": 2, "species_10051072": 2, "F1N6T4": 2, "ENSBTAT00000047964": 1, "reaction_10077890": 5, "species_6788802": 5, "species_6788801": 5, "species_10077887": 2, "ENSBTAT00000043366": 1, "reaction_10082948": 5, "species_6810468": 1, "species_6810471": 1, "species_10082945": 2, "ENSBTAT00000000407": 1, "reaction_10035047": 5, "species_10035044": 2, "A0A3Q1MT44": 2, "ENSBTAT00000070515": 1, "reaction_10035481": 9, "reaction_10034953": 4, "species_73584": 1, "species_73588": 2, "species_10034950": 4, "E1BFN6": 2, "ENSBTAT00000029176": 1, "reaction_10036267": 5, "species_500420": 6, "CHEBI:28895": 2, "CHEBI:28070": 2, "species_500421": 4, "species_10036264": 3, "E1B8C1": 2, "ENSBTAT00000043576": 1, "reaction_10036209": 5, "species_500316": 4, "species_500318": 4, "reaction_10035009": 4, "species_73541": 1, "species_73617": 2, "reaction_10035011": 6, "species_73619": 1, "species_10034959": 4, "A0A3Q1MFR9": 2, "ENSBTAT00000086038": 1, "reaction_10036258": 5, "species_500414": 7, "CHEBI:46322": 1, "species_500415": 4, "reaction_10034962": 6, "reaction_10036229": 6, "species_500347": 7, "species_500346": 7, "reaction_10036247": 5, "species_10036244": 3, "Q32L46": 2, "ENSBTAT00000033700": 1, "reaction_10065163": 2, "species_10065129": 6, "P85521": 3, "ENSBTAT00000026215": 1, "species_10065161": 6, "reaction_10064765": 3, "species_10064755": 4, "A0A452DI25": 5, "ENSBTAT00000004635": 2, "species_10064761": 2, "ENSBTAT00000017556": 2, "species_10064763": 5, "E1BGJ0": 3, "reaction_10064753": 4, "species_10064747": 3, "species_10064751": 3, "reaction_10064757": 3, "reaction_10065173": 2, "species_10065171": 5 }, "max_value": 0, "max_stat": 1, "categories": [], "labels": null, "blocklist": null, "species_blocklist": [], "metadata": { "cmd": "curate", "output": "/scratch/general/lustre/u0690617/2654255/BTA/", "organism_id": "BTA", "organism_curation_file": "/scratch/general/lustre/u0690617/2654255/BTA/BTA.mvdb", "neighbor_dictionary_file": null, "graph_template_file": null, "output_file": "/scratch/general/lustre/u0690617/2654255/BTA/BTA.mvrs", "transcriptomics": "None", "proteomics": "None", "metabolomics": "None", "database_source": "reactome", "force_new_curation": true, "collapse_with_modifiers": false, "broadcast_genes": false, "broadcast_metabolites": false, "experiment_type": null, "experiment_name": null, "labels": null, "blocklist": null, "collapse_threshold": 0.3, "session_data": null, "progress_log": null, "path": "/scratch/local/u0690617/2654255/_MEIu0mISH/", "network": "/scratch/general/lustre/u0690617/2654255/BTA/BTA.mvdb", "curation": "BTA.mvdb", "max_value": 0, "max_stat": 1, "model_version": "0.7.1", "model_date": "2021-06-07", "curation_date": "2021-06-07", "curation_version": "0.7.1", "template_url": "/scratch/general/lustre/u0690617/2654255/BTA/BTA_template.mvrs", "template_version": "0.7.1", "template_date": "2021-06-07" }, "unmapped": [] }